JP5944313B2 - 特定の化学物質、組成物および方法 - Google Patents
特定の化学物質、組成物および方法 Download PDFInfo
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- JP5944313B2 JP5944313B2 JP2012520630A JP2012520630A JP5944313B2 JP 5944313 B2 JP5944313 B2 JP 5944313B2 JP 2012520630 A JP2012520630 A JP 2012520630A JP 2012520630 A JP2012520630 A JP 2012520630A JP 5944313 B2 JP5944313 B2 JP 5944313B2
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- 0 BN(C1=O)C(N(CC2=NCNc3c2nc[n]3N)O*)=C(*)C(C2*)C1=C(*)C(*)C2(CCC)[As] Chemical compound BN(C1=O)C(N(CC2=NCNc3c2nc[n]3N)O*)=C(*)C(C2*)C1=C(*)C(*)C2(CCC)[As] 0.000 description 14
- NMASYHOFIZHNNO-UHFFFAOYSA-N C/C(/N)=N\CCN Chemical compound C/C(/N)=N\CCN NMASYHOFIZHNNO-UHFFFAOYSA-N 0.000 description 1
- XUDBXNYPRKQWCD-OZUDNVCOSA-N C[C@@H](C(N(C1O)/C=C/C(/N=C)=C\C=C/I)=Cc2c1cccc2)Nc1ncnc2c1nc[nH]2 Chemical compound C[C@@H](C(N(C1O)/C=C/C(/N=C)=C\C=C/I)=Cc2c1cccc2)Nc1ncnc2c1nc[nH]2 XUDBXNYPRKQWCD-OZUDNVCOSA-N 0.000 description 1
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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- C07D473/36—Sulfur atom
- C07D473/38—Sulfur atom attached in position 6
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- C07D473/32—Nitrogen atom
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/503,776 US8193182B2 (en) | 2008-01-04 | 2009-07-15 | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
US12/503,776 | 2009-07-15 | ||
PCT/US2010/002020 WO2011008302A1 (en) | 2009-07-15 | 2010-07-15 | Certain chemical entities, compositions and methods |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016103832A Division JP6158395B2 (ja) | 2009-07-15 | 2016-05-25 | 特定の化学物質、組成物および方法 |
Publications (3)
Publication Number | Publication Date |
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JP2012533541A JP2012533541A (ja) | 2012-12-27 |
JP2012533541A5 JP2012533541A5 (en:Method) | 2016-03-17 |
JP5944313B2 true JP5944313B2 (ja) | 2016-07-05 |
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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JP2012520630A Active JP5944313B2 (ja) | 2009-07-15 | 2010-07-15 | 特定の化学物質、組成物および方法 |
JP2016103832A Active JP6158395B2 (ja) | 2009-07-15 | 2016-05-25 | 特定の化学物質、組成物および方法 |
Family Applications After (1)
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JP2016103832A Active JP6158395B2 (ja) | 2009-07-15 | 2016-05-25 | 特定の化学物質、組成物および方法 |
Country Status (33)
Families Citing this family (176)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1583562E (pt) * | 2003-01-06 | 2011-09-19 | Angiochem Inc | Angiopep-1, compostos relacionados, e suas utilizações |
EP1831225A2 (en) | 2004-11-19 | 2007-09-12 | The Regents of the University of California | Anti-inflammatory pyrazolopyrimidines |
US7834181B2 (en) * | 2005-02-01 | 2010-11-16 | Slaon-Kettering Institute For Cancer Research | Small-molecule Hsp90 inhibitors |
US9403828B2 (en) | 2005-02-01 | 2016-08-02 | Sloan-Kettering Institute For Cancer Research | Small-molecule Hsp90 inhibitors |
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