HRP20160990T1 - Pc5 kao enzim obrade faktor ix propeptida - Google Patents

Pc5 kao enzim obrade faktor ix propeptida

Info

Publication number
HRP20160990T1
HRP20160990T1 HRP20160990TT HRP20160990T HRP20160990T1 HR P20160990 T1 HRP20160990 T1 HR P20160990T1 HR P20160990T T HRP20160990T T HR P20160990TT HR P20160990 T HRP20160990 T HR P20160990T HR P20160990 T1 HRP20160990 T1 HR P20160990T1
Authority
HR
Croatia
Prior art keywords
factor
processing enzyme
propeptide processing
propeptide
enzyme
Prior art date
Application number
HRP20160990TT
Other languages
English (en)
Inventor
Robert T. Peters
Alan Bitonti
Original Assignee
Biogen Hemophilia Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Hemophilia Inc. filed Critical Biogen Hemophilia Inc.
Publication of HRP20160990T1 publication Critical patent/HRP20160990T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6454—Dibasic site splicing serine proteases, e.g. kexin (3.4.21.61); furin (3.4.21.75) and other proprotein convertases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HRP20160990TT 2006-03-24 2016-08-04 Pc5 kao enzim obrade faktor ix propeptida HRP20160990T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78542106P 2006-03-24 2006-03-24
EP07753848.6A EP2004683B1 (en) 2006-03-24 2007-03-23 Pc5 as a factor ix propeptide processing enzyme
PCT/US2007/007252 WO2007112005A2 (en) 2006-03-24 2007-03-23 Pc5 as a factor ix propeptide processing enzyme

Publications (1)

Publication Number Publication Date
HRP20160990T1 true HRP20160990T1 (hr) 2016-10-07

Family

ID=38541681

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20160990TT HRP20160990T1 (hr) 2006-03-24 2016-08-04 Pc5 kao enzim obrade faktor ix propeptida

Country Status (10)

Country Link
US (3) US7566565B2 (hr)
EP (2) EP2004683B1 (hr)
DK (1) DK2004683T3 (hr)
HK (1) HK1125656A1 (hr)
HR (1) HRP20160990T1 (hr)
HU (1) HUE030567T2 (hr)
LT (1) LT2004683T (hr)
SI (1) SI2004683T1 (hr)
TW (1) TWI428448B (hr)
WO (1) WO2007112005A2 (hr)

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Also Published As

Publication number Publication date
HK1125656A1 (zh) 2009-08-14
HUE030567T2 (en) 2017-05-29
SI2004683T1 (sl) 2016-09-30
US20100015659A1 (en) 2010-01-21
US20110053222A1 (en) 2011-03-03
WO2007112005A2 (en) 2007-10-04
US8021880B2 (en) 2011-09-20
EP2004683B1 (en) 2016-05-11
LT2004683T (lt) 2016-10-10
EP2004683A2 (en) 2008-12-24
TW200815599A (en) 2008-04-01
TWI428448B (zh) 2014-03-01
US20070259402A1 (en) 2007-11-08
US7566565B2 (en) 2009-07-28
US7795400B2 (en) 2010-09-14
EP2650305A1 (en) 2013-10-16
EP2650305B1 (en) 2024-05-08
WO2007112005A3 (en) 2008-02-07
DK2004683T3 (en) 2016-08-22

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