LT2004683T - Pc5, kaip faktoriaus ix pro-peptidą apdorojantis fermentas - Google Patents

Pc5, kaip faktoriaus ix pro-peptidą apdorojantis fermentas

Info

Publication number
LT2004683T
LT2004683T LTEP07753848.6T LT07753848T LT2004683T LT 2004683 T LT2004683 T LT 2004683T LT 07753848 T LT07753848 T LT 07753848T LT 2004683 T LT2004683 T LT 2004683T
Authority
LT
Lithuania
Prior art keywords
factor
processing enzyme
propeptide processing
propeptide
enzyme
Prior art date
Application number
LTEP07753848.6T
Other languages
English (en)
Inventor
Robert T. Peters
Alan Bitonti
Original Assignee
Biogen Hemophilia Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Hemophilia Inc. filed Critical Biogen Hemophilia Inc.
Publication of LT2004683T publication Critical patent/LT2004683T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6454—Dibasic site splicing serine proteases, e.g. kexin (3.4.21.61); furin (3.4.21.75) and other proprotein convertases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
LTEP07753848.6T 2006-03-24 2007-03-23 Pc5, kaip faktoriaus ix pro-peptidą apdorojantis fermentas LT2004683T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78542106P 2006-03-24 2006-03-24
PCT/US2007/007252 WO2007112005A2 (en) 2006-03-24 2007-03-23 Pc5 as a factor ix propeptide processing enzyme

Publications (1)

Publication Number Publication Date
LT2004683T true LT2004683T (lt) 2016-10-10

Family

ID=38541681

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP07753848.6T LT2004683T (lt) 2006-03-24 2007-03-23 Pc5, kaip faktoriaus ix pro-peptidą apdorojantis fermentas

Country Status (11)

Country Link
US (3) US7566565B2 (lt)
EP (2) EP2650305B1 (lt)
DK (1) DK2004683T3 (lt)
ES (1) ES2987558T3 (lt)
HR (1) HRP20160990T1 (lt)
HU (2) HUE067285T2 (lt)
LT (1) LT2004683T (lt)
PL (1) PL2650305T3 (lt)
SI (1) SI2004683T1 (lt)
TW (1) TWI428448B (lt)
WO (1) WO2007112005A2 (lt)

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Also Published As

Publication number Publication date
US20100015659A1 (en) 2010-01-21
TW200815599A (en) 2008-04-01
PL2650305T3 (pl) 2024-09-16
EP2004683A2 (en) 2008-12-24
EP2004683B1 (en) 2016-05-11
HUE067285T2 (hu) 2024-10-28
EP2650305B1 (en) 2024-05-08
EP2650305C0 (en) 2024-05-08
HK1125656A1 (zh) 2009-08-14
EP2650305A1 (en) 2013-10-16
US8021880B2 (en) 2011-09-20
US7566565B2 (en) 2009-07-28
US20070259402A1 (en) 2007-11-08
ES2987558T3 (es) 2024-11-15
SI2004683T1 (sl) 2016-09-30
DK2004683T3 (en) 2016-08-22
HUE030567T2 (en) 2017-05-29
WO2007112005A2 (en) 2007-10-04
TWI428448B (zh) 2014-03-01
HRP20160990T1 (hr) 2016-10-07
WO2007112005A3 (en) 2008-02-07
US20110053222A1 (en) 2011-03-03
US7795400B2 (en) 2010-09-14

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