ES2516815T3 - Análogos de ácidos nucleicos bicíclicos modificados en la posición 6 - Google Patents

Análogos de ácidos nucleicos bicíclicos modificados en la posición 6 Download PDF

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Publication number
ES2516815T3
ES2516815T3 ES10176867.9T ES10176867T ES2516815T3 ES 2516815 T3 ES2516815 T3 ES 2516815T3 ES 10176867 T ES10176867 T ES 10176867T ES 2516815 T3 ES2516815 T3 ES 2516815T3
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oligomeric compound
mmol
nucleoside
substituted
group
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English (en)
Spanish (es)
Inventor
Eric E. Swayze
Punit P. Seth
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Ionis Pharmaceuticals Inc
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Isis Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES10176867.9T 2006-01-27 2007-01-27 Análogos de ácidos nucleicos bicíclicos modificados en la posición 6 Active ES2516815T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US76272206P 2006-01-27 2006-01-27
US762722P 2006-01-27
US80566006P 2006-06-23 2006-06-23
US805660P 2006-06-23

Publications (1)

Publication Number Publication Date
ES2516815T3 true ES2516815T3 (es) 2014-10-31

Family

ID=38328111

Family Applications (2)

Application Number Title Priority Date Filing Date
ES10176867.9T Active ES2516815T3 (es) 2006-01-27 2007-01-27 Análogos de ácidos nucleicos bicíclicos modificados en la posición 6
ES07762892T Active ES2351674T3 (es) 2006-01-27 2007-01-27 Análogos de ácidos nucleicos bicíclicos modificados en la posición 6.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES07762892T Active ES2351674T3 (es) 2006-01-27 2007-01-27 Análogos de ácidos nucleicos bicíclicos modificados en la posición 6.

Country Status (13)

Country Link
US (3) US7399845B2 (https=)
EP (3) EP2332951A3 (https=)
JP (2) JP5342881B2 (https=)
KR (2) KR101304071B1 (https=)
CN (3) CN102766630B (https=)
AT (1) ATE482965T1 (https=)
AU (1) AU2007211080B9 (https=)
CA (1) CA2640171C (https=)
DE (1) DE602007009487D1 (https=)
DK (2) DK1984381T3 (https=)
ES (2) ES2516815T3 (https=)
PL (2) PL1984381T3 (https=)
WO (1) WO2007090071A2 (https=)

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CN102766630B (zh) 2014-05-07
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KR20080088662A (ko) 2008-10-02
US20100216979A1 (en) 2010-08-26
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EP1984381B1 (en) 2010-09-29
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