DK3094728T3 - Kiralt design - Google Patents

Kiralt design Download PDF

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Publication number
DK3094728T3
DK3094728T3 DK15719826.8T DK15719826T DK3094728T3 DK 3094728 T3 DK3094728 T3 DK 3094728T3 DK 15719826 T DK15719826 T DK 15719826T DK 3094728 T3 DK3094728 T3 DK 3094728T3
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kiralt
design
kiralt design
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DK15719826.8T
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Danish (da)
English (en)
Inventor
Meena
Naoki Iwamoto
Nenad Svrzikapa
Ivan Zlatev
Gregory L Verdine
David Butler
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Wave Life Sciences Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/31Chemical structure of the backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/31Chemical structure of the backbone
    • C12N2310/315Phosphorothioates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Window Of Vehicle (AREA)
  • Liquid Crystal Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK15719826.8T 2014-01-16 2015-01-16 Kiralt design DK3094728T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461928405P 2014-01-16 2014-01-16
US201462063359P 2014-10-13 2014-10-13
PCT/IB2015/000395 WO2015107425A2 (en) 2014-01-16 2015-01-16 Chiral design

Publications (1)

Publication Number Publication Date
DK3094728T3 true DK3094728T3 (da) 2022-05-16

Family

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Family Applications (1)

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DK15719826.8T DK3094728T3 (da) 2014-01-16 2015-01-16 Kiralt design

Country Status (19)

Country Link
US (4) US10160969B2 (enExample)
EP (2) EP4137572A1 (enExample)
JP (5) JP6382344B2 (enExample)
KR (5) KR20230152178A (enExample)
CN (2) CN113278617A (enExample)
AU (3) AU2015207773B2 (enExample)
BR (1) BR112016016400A2 (enExample)
CA (1) CA2936712A1 (enExample)
CL (1) CL2016001814A1 (enExample)
DK (1) DK3094728T3 (enExample)
ES (1) ES2917473T3 (enExample)
IL (1) IL246703A0 (enExample)
MX (1) MX2016009290A (enExample)
MY (1) MY193116A (enExample)
PL (1) PL3094728T3 (enExample)
PT (1) PT3094728T (enExample)
RU (1) RU2016133035A (enExample)
SG (2) SG11201605782UA (enExample)
WO (1) WO2015107425A2 (enExample)

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* Cited by examiner, † Cited by third party
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US10815482B2 (en) 2020-10-27
US20190106696A1 (en) 2019-04-11
RU2016133035A (ru) 2018-02-21
KR20220106232A (ko) 2022-07-28
KR20160107326A (ko) 2016-09-13
WO2015107425A3 (en) 2016-01-14
EP3094728B1 (en) 2022-03-09
KR20230152178A (ko) 2023-11-02
KR102423317B1 (ko) 2022-07-22
JP6757373B2 (ja) 2020-09-16
PL3094728T3 (pl) 2022-07-04

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