CA2636855C - Microfluidic devices and methods of use in the formation and control of nanoreactors - Google Patents

Microfluidic devices and methods of use in the formation and control of nanoreactors Download PDF

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Publication number
CA2636855C
CA2636855C CA2636855A CA2636855A CA2636855C CA 2636855 C CA2636855 C CA 2636855C CA 2636855 A CA2636855 A CA 2636855A CA 2636855 A CA2636855 A CA 2636855A CA 2636855 C CA2636855 C CA 2636855C
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droplets
droplet
channel
fluid
cells
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French (fr)
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CA2636855A1 (en
Inventor
Darren R. Link
Laurent Boitard
Jeffrey Branciforte
Yves Charles
Gilbert Feke
John Q. Lu
David Marran
Ahmadali Tabatabai
Michael Weiner
Wolfgang Hinz
Jonathan M. Rothberg
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Bio Rad Laboratories Inc
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Raindance Technologies Inc
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1075Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
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