MX2018010800A - Sistemas y metodos para la deteccion de alergenos. - Google Patents

Sistemas y metodos para la deteccion de alergenos.

Info

Publication number
MX2018010800A
MX2018010800A MX2018010800A MX2018010800A MX2018010800A MX 2018010800 A MX2018010800 A MX 2018010800A MX 2018010800 A MX2018010800 A MX 2018010800A MX 2018010800 A MX2018010800 A MX 2018010800A MX 2018010800 A MX2018010800 A MX 2018010800A
Authority
MX
Mexico
Prior art keywords
detection
sample
spns
allergens
methods
Prior art date
Application number
MX2018010800A
Other languages
English (en)
Inventor
Gilboa-Geffen Adi
Babu BROWN Renuka
Murphy Patrick
STIDHAM Sarah
Villareal Valerie
Glenn ANTHONY Joshua
H Kepler John
Jacobs Adam
J Young Adam
Original Assignee
Dots Tech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dots Tech Corp filed Critical Dots Tech Corp
Publication of MX2018010800A publication Critical patent/MX2018010800A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02—Food
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C12M1/3446—Photometry, spectroscopy, laser technology
    • C12M1/3476—Fluorescence spectroscopy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G01N33/5304—Reaction vessels, e.g. agglutination plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/10—Applications; Uses in screening processes
    • C12N2320/11—Applications; Uses in screening processes for the determination of target sites, i.e. of active nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices
    • G01N2001/1418—Depression, aspiration
    • G01N2001/1427—Positive displacement, piston, peristaltic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2866—Grinding or homogeneising

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Hydrology & Water Resources (AREA)
  • Plant Pathology (AREA)
  • Optics & Photonics (AREA)
  • Sustainable Development (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

La presente invención proporciona sistemas, dispositivos, polinucleótidos de señalización (SPN, por sus siglas en inglés), agentes de detección y métodos para determinar la presencia o ausencia de uno o más alergenos en una muestra, particularmente una muestra de alimentos. El sistema de detección incluye un muestreador por separado, al menos un recipiente de detección desechable para la recepción y procesamiento de una muestra, así como dispositivo de detección para medir una señal de fluorescencia. Se proporcionan como agentes de detección, SPN derivados de aptámeros que se unen a los alergenos. Los SPN tienen una estructura única abierta y están marcados con un fluoróforo. Se miden los cambios en la polarización de fluorescencia de los SPN cuando se unen a los alergenos, con el fin de calcular el contenido de alergenos en una muestra.
MX2018010800A 2016-03-15 2017-03-10 Sistemas y metodos para la deteccion de alergenos. MX2018010800A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662308377P 2016-03-15 2016-03-15
US201662308376P 2016-03-15 2016-03-15
PCT/US2017/021737 WO2017160616A1 (en) 2016-03-15 2017-03-10 Systems and methods for allergen detection

Publications (1)

Publication Number Publication Date
MX2018010800A true MX2018010800A (es) 2018-11-09

Family

ID=59851843

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018010800A MX2018010800A (es) 2016-03-15 2017-03-10 Sistemas y metodos para la deteccion de alergenos.

Country Status (9)

Country Link
US (2) US10908139B2 (es)
EP (1) EP3429741A4 (es)
JP (1) JP2019511715A (es)
CN (1) CN108780027A (es)
AU (1) AU2017234548B2 (es)
CA (1) CA3013386A1 (es)
MX (1) MX2018010800A (es)
SG (1) SG11201806647VA (es)
WO (1) WO2017160616A1 (es)

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FR3098917B1 (fr) * 2019-07-17 2024-04-26 Commissariat Energie Atomique Procédé et système de détection d'un analyte présent dans un échantillon liquide
US20220341824A1 (en) * 2019-09-11 2022-10-27 Global Biyomedikal Saglik Hizmetleri Sana Yi Ve Ti Caret Limited Sirketi Tissue Disaggregation, Homogenization, Photoactivation Device
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US10927404B1 (en) * 2020-06-26 2021-02-23 4233999 Canada Inc. Pathogen detection using aptamer molecular beacons using a mobile device
US11053556B1 (en) * 2020-06-26 2021-07-06 4233999 Canada Inc. Pathogen detection using aptamer molecular photonic beacons using a mobile device
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FR3128021B1 (fr) * 2021-10-12 2024-05-17 Univ Grenoble Alpes Procédé de détection d’un analyte cible dans un échantillon à l’aide de Bleu du Nil, composition pour la détection d’un analyte cible et son utilisation.
CN114075565B (zh) * 2022-01-19 2022-04-19 中国农业大学 一种用于检测β-乳球蛋白的双功能G-四链体变构生物传感器
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Also Published As

Publication number Publication date
SG11201806647VA (en) 2018-09-27
US20190079063A1 (en) 2019-03-14
US10908139B2 (en) 2021-02-02
JP2019511715A (ja) 2019-04-25
US20210109076A1 (en) 2021-04-15
CA3013386A1 (en) 2017-09-21
AU2017234548B2 (en) 2021-03-25
WO2017160616A1 (en) 2017-09-21
EP3429741A4 (en) 2019-11-27
EP3429741A1 (en) 2019-01-23
CN108780027A (zh) 2018-11-09
AU2017234548A1 (en) 2018-08-30

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