LU91497I2 - Rivaroxaban et ses sels pharmaceutiquement acceptables,hydrates,hydrates de ces sels et promédicaments - Google Patents

Rivaroxaban et ses sels pharmaceutiquement acceptables,hydrates,hydrates de ces sels et promédicaments

Info

Publication number
LU91497I2
LU91497I2 LU91497C LU91497C LU91497I2 LU 91497 I2 LU91497 I2 LU 91497I2 LU 91497 C LU91497 C LU 91497C LU 91497 C LU91497 C LU 91497C LU 91497 I2 LU91497 I2 LU 91497I2
Authority
LU
Luxembourg
Prior art keywords
hydrates
salts
prodrugs
benzo
optionally
Prior art date
Application number
LU91497C
Other languages
English (en)
Other versions
LU91497I9 (fr
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7934434&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU91497(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of LU91497I2 publication Critical patent/LU91497I2/fr
Publication of LU91497I9 publication Critical patent/LU91497I9/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
LU91497C 1999-12-24 2008-11-19 Rivaroxaban et ses sels pharmaceutiquement acceptables,hydrates,hydrates de ces sels et promédicaments LU91497I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19962924A DE19962924A1 (de) 1999-12-24 1999-12-24 Substituierte Oxazolidinone und ihre Verwendung
PCT/EP2000/012492 WO2001047919A1 (fr) 1999-12-24 2000-12-11 Oxazolidinones substituees et leur utilisation dans le domaine de la coagulation sanguine

Publications (2)

Publication Number Publication Date
LU91497I2 true LU91497I2 (fr) 2009-01-19
LU91497I9 LU91497I9 (fr) 2019-01-02

Family

ID=7934434

Family Applications (1)

Application Number Title Priority Date Filing Date
LU91497C LU91497I2 (fr) 1999-12-24 2008-11-19 Rivaroxaban et ses sels pharmaceutiquement acceptables,hydrates,hydrates de ces sels et promédicaments

Country Status (50)

Country Link
US (8) US7157456B2 (fr)
EP (2) EP1261606B1 (fr)
JP (2) JP4143297B2 (fr)
KR (3) KR20070094672A (fr)
CN (3) CN1900074B (fr)
AR (1) AR032436A1 (fr)
AT (1) ATE289605T1 (fr)
AU (2) AU775126C (fr)
BE (1) BE2008C046I2 (fr)
BG (1) BG65683B1 (fr)
BR (1) BR0017050B1 (fr)
CA (1) CA2396561C (fr)
CO (1) CO5251440A1 (fr)
CU (2) CU23208A3 (fr)
CY (2) CY2008019I1 (fr)
CZ (1) CZ301432B6 (fr)
DE (3) DE19962924A1 (fr)
DK (2) DK1261606T3 (fr)
DO (2) DOP2000000114A (fr)
EE (1) EE05169B1 (fr)
ES (2) ES2237497T3 (fr)
FR (1) FR08C0051I2 (fr)
GT (1) GT200000216A (fr)
HK (3) HK1092140A1 (fr)
HN (1) HN2000000267A (fr)
HR (2) HRP20020617B1 (fr)
HU (1) HU226522B1 (fr)
IL (2) IL149896A0 (fr)
LT (1) LTC1261606I2 (fr)
LU (1) LU91497I2 (fr)
MA (1) MA25646A1 (fr)
MX (1) MXPA02006241A (fr)
MY (1) MY140488A (fr)
NL (1) NL300370I2 (fr)
NO (4) NO323699B1 (fr)
NZ (2) NZ519730A (fr)
PE (1) PE20010963A1 (fr)
PL (2) PL200413B1 (fr)
PT (2) PT1261606E (fr)
RU (1) RU2297415C2 (fr)
SG (1) SG130939A1 (fr)
SI (2) SI1261606T1 (fr)
SK (1) SK287272B6 (fr)
SV (1) SV2002000245A (fr)
TR (2) TR200201636T2 (fr)
TW (2) TWI277615B (fr)
UA (1) UA73339C2 (fr)
UY (1) UY34152A (fr)
WO (1) WO2001047919A1 (fr)
ZA (1) ZA200204188B (fr)

Families Citing this family (246)

* Cited by examiner, † Cited by third party
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BG106825A (en) 2003-02-28
SK287272B6 (sk) 2010-05-07
NO2009001I1 (no) 2009-02-02
TR200201636T2 (tr) 2002-10-21
US7592339B2 (en) 2009-09-22
US8822458B2 (en) 2014-09-02
CA2396561C (fr) 2008-10-14
CN1900074B (zh) 2012-07-11
ATE289605T1 (de) 2005-03-15
DE122009000014I1 (de) 2009-11-05
HK1092140A1 (en) 2007-02-02
CY1115117T1 (el) 2016-12-14
US7585860B2 (en) 2009-09-08
NZ537058A (en) 2006-04-28
ES2457021T3 (es) 2014-04-24
CY2008019I1 (el) 2009-11-04
JP5190173B2 (ja) 2013-04-24
US20030153610A1 (en) 2003-08-14
US20130316999A1 (en) 2013-11-28
EP1526132A3 (fr) 2005-08-31

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