DE69616366T2 - Phenyloxazolidinone mit einer c-c-bindung zu 4-8 gliedrigen heterocyclen - Google Patents

Phenyloxazolidinone mit einer c-c-bindung zu 4-8 gliedrigen heterocyclen

Info

Publication number
DE69616366T2
DE69616366T2 DE69616366T DE69616366T DE69616366T2 DE 69616366 T2 DE69616366 T2 DE 69616366T2 DE 69616366 T DE69616366 T DE 69616366T DE 69616366 T DE69616366 T DE 69616366T DE 69616366 T2 DE69616366 T2 DE 69616366T2
Authority
DE
Germany
Prior art keywords
alkyl
halo
aryl
methyl
substd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69616366T
Other languages
English (en)
Other versions
DE69616366D1 (de
Inventor
K Hutchinson
D Ennis
L Hoffman
C Thomas
Toni-Jo Poel
Robert Barbachyn
J Brickner
J Anderson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Application granted granted Critical
Publication of DE69616366D1 publication Critical patent/DE69616366D1/de
Publication of DE69616366T2 publication Critical patent/DE69616366T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
DE69616366T 1995-09-01 1996-08-13 Phenyloxazolidinone mit einer c-c-bindung zu 4-8 gliedrigen heterocyclen Expired - Fee Related DE69616366T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US314995P 1995-09-01 1995-09-01
PCT/US1996/012766 WO1997009328A1 (en) 1995-09-01 1996-08-13 Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings

Publications (2)

Publication Number Publication Date
DE69616366D1 DE69616366D1 (de) 2001-11-29
DE69616366T2 true DE69616366T2 (de) 2002-07-04

Family

ID=21704418

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69616366T Expired - Fee Related DE69616366T2 (de) 1995-09-01 1996-08-13 Phenyloxazolidinone mit einer c-c-bindung zu 4-8 gliedrigen heterocyclen

Country Status (27)

Country Link
US (7) US5968962A (de)
EP (1) EP0856002B1 (de)
JP (1) JPH11512386A (de)
KR (1) KR100463772B1 (de)
CN (1) CN1072222C (de)
AT (1) ATE207487T1 (de)
AU (1) AU716493B2 (de)
BR (1) BR9610474A (de)
CA (1) CA2228647A1 (de)
CZ (1) CZ49398A3 (de)
DE (1) DE69616366T2 (de)
DK (1) DK0856002T3 (de)
ES (1) ES2165516T3 (de)
FI (1) FI980452A0 (de)
HK (1) HK1014946A1 (de)
HU (1) HUP9901979A3 (de)
MX (1) MX9801578A (de)
NO (1) NO311520B1 (de)
NZ (1) NZ315469A (de)
PL (1) PL186524B1 (de)
PT (1) PT856002E (de)
RU (1) RU2175324C2 (de)
SK (1) SK283487B6 (de)
TW (1) TW419468B (de)
UA (1) UA52620C2 (de)
WO (1) WO1997009328A1 (de)
ZA (1) ZA966935B (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9901979A3 (en) * 1995-09-01 2000-03-28 Upjohn Co Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings and pharmaceutical compositions containing the same
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
KR20010021645A (ko) * 1997-07-11 2001-03-15 로렌스 티. 마이젠헬더 티아디아졸릴 및 옥사디아졸릴 페닐 옥사졸리디논 항균제
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US6083967A (en) * 1997-12-05 2000-07-04 Pharmacia & Upjohn Company S-oxide and S,S-dioxide tetrahydrothiopyran phenyloxazolidinones
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
CA2318969A1 (en) 1998-01-23 1999-07-29 Mikhail F. Gordeev Oxazolidinone combinatorial libraries, compositions and methods of preparation
EE200000707A (et) 1998-06-05 2002-04-15 Astrazeneca Ab Oksasolidinooni derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
EP1229033B8 (de) * 1999-02-01 2005-06-15 Pharmacia & Upjohn Company LLC 2-Fluoro-(oxido-Thiopyran-4-yl)Benzol Derivate
ATE235486T1 (de) 1999-02-01 2003-04-15 Upjohn Co Verfahren zu herstellung von o-fluorierten tetrahydrothiopyran carbamaten
MY120189A (en) * 1999-11-04 2005-09-30 Upjohn Co Sultam and sultone derived oxazolidinones
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
NZ519725A (en) * 1999-12-21 2004-05-28 Upjohn Co Oxazolidinones having a sulfoximine functionality and their use as antimicrobial agents
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
MY127336A (en) 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
PE20020044A1 (es) 2000-06-16 2002-01-30 Upjohn Co Tiazina oxazolidinona
DK1301207T3 (da) 2000-06-30 2005-10-10 Pharmacia & Upjohn Co Llc Sammensætninger til behandling af bakterieinfektioner indeholdende en oxazolidinonforbindelse, sulbactam og ampicillin
JP2004531518A (ja) * 2001-04-07 2004-10-14 アストラゼネカ アクチボラグ スルホンイミド基を含有する、抗生物質としてのオキサゾリジノン
GB0108764D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
MXPA03009645A (es) * 2001-04-20 2004-01-29 Upjohn Co Proceso para preparar oxazolidinonas.
CA2439959A1 (en) 2001-04-20 2002-10-31 Pharmacia & Upjohn Company A method for the preparation of oxazolidinones
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
CA2452513A1 (en) * 2001-07-12 2003-01-23 Pharmacia & Upjohn Company Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound
US7125568B2 (en) 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
ATE369362T1 (de) * 2002-01-24 2007-08-15 Pharmacia & Upjohn Co Llc Antimikrobielle dihydrothiazin- und dihydrothiopyranoxazolidinone
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
BR0308806A (pt) * 2002-03-29 2005-01-04 Upjohn Co Uso de oxazolidinonas para tratar infecções do tipo pé diabético
WO2003097640A1 (en) * 2002-05-22 2003-11-27 Orchid Chemicals & Pharmaceuticals Ltd. Oxazolidinone derivatives as antibacterial agents
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
TW200404069A (en) * 2002-06-28 2004-03-16 Upjohn Co Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent
ATE321760T1 (de) * 2002-08-12 2006-04-15 Pharmacia & Upjohn Co Llc N-aryl-2-oxazolidinone und deren derivate
ES2271660T3 (es) * 2002-11-21 2007-04-16 PHARMACIA & UPJOHN COMPANY LLC Derivados de n-(4-piperazin-1-il)-fenil-2-oxazolidinona-5-carboxamida y compuestos relacionados como agentes antibacterianos.
DE10300111A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
BRPI0407304A (pt) * 2003-02-07 2006-01-10 Warner Lambert Co Agentes antibacterianos
WO2004069832A2 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
WO2004099199A1 (en) * 2003-05-06 2004-11-18 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
WO2004113329A1 (en) * 2003-06-20 2004-12-29 Orchid Chemicals And Pharmaceuticals Ltd. Oxazole derivatives as antibacterial agents
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
US7265140B2 (en) 2003-09-23 2007-09-04 Pfizer Inc Acyloxymethylcarbamate prodrugs of oxazolidinones
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
WO2005082892A2 (en) * 2004-02-17 2005-09-09 Dr. Reddy's Laboratories Ltd. Triazole compounds as antibacterial agents and pharmaceutical compositions containing them
EA200700322A1 (ru) * 2004-08-06 2007-08-31 Фармация Энд Апджон Компани Ллс Оксазолидиноны, содержащие оксиндолы, в качестве антибактериальных агентов
EP1685841A1 (de) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prophylaxe und Behandlung von thrombolischen Erkrankungen
DE102005045518A1 (de) 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
WO2007039132A1 (de) 2005-10-04 2007-04-12 Bayer Healthcare Ag Neue polymorphe form und die amorphe form von 5-chlor-n- ( { ( 5s ) -2-0x0-3-[4-( 3-oxo-4-morpholinyl) - phenyl] -1,3-oxazolidin-5-yl} -methyl) -2- thiophencarboxamid
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
WO2007114326A1 (ja) 2006-03-31 2007-10-11 Research Foundation Itsuu Laboratory ヘテロ環を有する新規化合物
US7875958B2 (en) * 2006-09-27 2011-01-25 Taiwan Semiconductor Manufacturing Company, Ltd. Quantum tunneling devices and circuits with lattice-mismatched semiconductor structures
WO2008143649A2 (en) * 2006-12-04 2008-11-27 Dr. Reddy's Laboratories Limited Novel oxazolidinone compounds as antiinfective agents
US8395996B2 (en) * 2007-01-11 2013-03-12 Foundry Networks, Llc Techniques for processing incoming failure detection protocol packets
CL2008001003A1 (es) * 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
WO2009044777A1 (ja) 2007-10-02 2009-04-09 Research Foundation Itsuu Laboratory 7員ヘテロ環を有するオキサゾリジノン誘導体
KR101023174B1 (ko) * 2008-09-24 2011-03-18 주식회사 레고켐 바이오사이언스 사이클릭 아미독심 또는 사이클릭 아미드라존 기를 가지는 신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물
JP5662940B2 (ja) 2008-11-20 2015-02-04 パナセア バイオテック リミテッド 新規な抗微生物薬
AU2011300365A1 (en) * 2010-09-07 2013-05-02 Symed Labs Limited Processes for the preparation of 4-{4-[5(S)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl} morpholin-3-one
AR093396A1 (es) * 2012-11-09 2015-06-03 Syngenta Participations Ag Derivados de dihidrotiofeno como compuestos insecticidas
EP3914587A4 (de) * 2019-01-18 2022-11-23 Merck Sharp & Dohme LLC Oxazolidinonverbindungen und verwendungen davon als antibakterielle mittel
US11919879B2 (en) 2021-06-16 2024-03-05 Celgene Corporation Carboxylic acid containing azetidinyl compounds for the treatment of neurodegenerative diseases
CN115724823B (zh) * 2021-08-27 2023-11-24 中国科学院大连化学物理研究所 一种制备二氢噻吩衍生物的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1250538A (de) * 1969-03-18 1971-10-20
FR2356422A1 (fr) * 1976-03-01 1978-01-27 Delalande Sa Nouveaux hydroxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR2380780A2 (fr) * 1977-02-22 1978-09-15 Delalande Sa Application en therapeutique des hydroxymethyl-5 oxazolidinones-2, notamment comme antidepresseurs
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
JPS59118721A (ja) * 1982-12-25 1984-07-09 Nippon Zeon Co Ltd カルボキシル化合物の製造方法
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
FR2574796B1 (fr) * 1984-12-18 1990-11-02 Kaseihin Cy Inc C S Procede de preparation de composes d'isocyanate contenant du silicium
US5130316A (en) * 1988-07-29 1992-07-14 Du Pont Merck Pharmaceutical Company Aminomethyloxooxazlidinyl arylbenzene derivatives useful as antibacterial agents
US5254577A (en) * 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
CA2119556C (en) * 1991-11-01 2004-07-06 Michael Robert Barbachyn Substituted aryl- and heteroaryl-phenyloxazolidinones
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5668286A (en) * 1994-03-15 1997-09-16 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
HUP9901979A3 (en) * 1995-09-01 2000-03-28 Upjohn Co Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings and pharmaceutical compositions containing the same
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
ATE293609T1 (de) * 1997-05-30 2005-05-15 Upjohn Co Antibakteriell wirksam oxazolidinone mit einer thiocarbonylfunktionalität
GB9717807D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
ATE235486T1 (de) * 1999-02-01 2003-04-15 Upjohn Co Verfahren zu herstellung von o-fluorierten tetrahydrothiopyran carbamaten
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents

Also Published As

Publication number Publication date
KR19990044238A (ko) 1999-06-25
UA52620C2 (uk) 2003-01-15
CN1072222C (zh) 2001-10-03
HUP9901979A2 (hu) 2000-02-28
US6043266A (en) 2000-03-28
NO980855L (no) 1998-04-30
ATE207487T1 (de) 2001-11-15
CZ49398A3 (cs) 1998-08-12
AU716493B2 (en) 2000-02-24
SK19598A3 (en) 1998-11-04
US6051716A (en) 2000-04-18
FI980452A (fi) 1998-02-27
AU6718196A (en) 1997-03-27
BR9610474A (pt) 1999-03-02
PT856002E (pt) 2002-04-29
PL186524B1 (pl) 2004-01-30
SK283487B6 (sk) 2003-08-05
US5968962A (en) 1999-10-19
TW419468B (en) 2001-01-21
ZA966935B (en) 1998-02-16
KR100463772B1 (ko) 2005-11-09
HUP9901979A3 (en) 2000-03-28
FI980452A0 (fi) 1998-02-27
US6313307B1 (en) 2001-11-06
US6166056A (en) 2000-12-26
WO1997009328A1 (en) 1997-03-13
NO980855D0 (no) 1998-02-27
RU2175324C2 (ru) 2001-10-27
DE69616366D1 (de) 2001-11-29
US6358942B1 (en) 2002-03-19
DK0856002T3 (da) 2002-02-11
US20050054683A1 (en) 2005-03-10
EP0856002A1 (de) 1998-08-05
EP0856002B1 (de) 2001-10-24
ES2165516T3 (es) 2002-03-16
NO311520B1 (no) 2001-12-03
PL325152A1 (en) 1998-07-06
JPH11512386A (ja) 1999-10-26
NZ315469A (en) 2000-01-28
CN1197457A (zh) 1998-10-28
HK1014946A1 (en) 1999-10-08
CA2228647A1 (en) 1997-03-13
MX9801578A (es) 1998-08-30

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