NO955104L - Anvendelse av 5-acyl-1,4-dihydropyridiner - Google Patents

Anvendelse av 5-acyl-1,4-dihydropyridiner

Info

Publication number
NO955104L
NO955104L NO955104A NO955104A NO955104L NO 955104 L NO955104 L NO 955104L NO 955104 A NO955104 A NO 955104A NO 955104 A NO955104 A NO 955104A NO 955104 L NO955104 L NO 955104L
Authority
NO
Norway
Prior art keywords
alkyl
prepn
dichlorophenyl
fluorophenyl
chlorophenyl
Prior art date
Application number
NO955104A
Other languages
English (en)
Other versions
NO955104D0 (no
NO309125B1 (no
Inventor
Klaus Urbahns
Hans-Georg Heine
Thomas Glaser
Reilinde Wittka
Jean-Marie-Viktor De Vry
Henning Sommermeyer
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO955104D0 publication Critical patent/NO955104D0/no
Publication of NO955104L publication Critical patent/NO955104L/no
Publication of NO309125B1 publication Critical patent/NO309125B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO955104A 1994-12-16 1995-12-15 Anvendelse av 1-alkyl-5-acyl-1,4-dihydropyridiner for fremstilling av legemidler som har en selektiv modulerende virkning på kaliumkanaler, samt utvalgte nye dihydropyridiner NO309125B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4444864A DE4444864A1 (de) 1994-12-16 1994-12-16 Verwendung von 5-Acyl-1,4-dihydropyridinen

Publications (3)

Publication Number Publication Date
NO955104D0 NO955104D0 (no) 1995-12-15
NO955104L true NO955104L (no) 1996-06-17
NO309125B1 NO309125B1 (no) 2000-12-18

Family

ID=6535989

Family Applications (1)

Application Number Title Priority Date Filing Date
NO955104A NO309125B1 (no) 1994-12-16 1995-12-15 Anvendelse av 1-alkyl-5-acyl-1,4-dihydropyridiner for fremstilling av legemidler som har en selektiv modulerende virkning på kaliumkanaler, samt utvalgte nye dihydropyridiner

Country Status (25)

Country Link
US (2) US5646166A (no)
EP (1) EP0717036B1 (no)
JP (1) JPH08239364A (no)
KR (1) KR960022464A (no)
CN (1) CN1130505A (no)
AT (1) ATE177735T1 (no)
AU (1) AU704466B2 (no)
CA (1) CA2165130A1 (no)
CZ (1) CZ332995A3 (no)
DE (2) DE4444864A1 (no)
DK (1) DK0717036T3 (no)
EE (1) EE9500075A (no)
ES (1) ES2130506T3 (no)
FI (1) FI956015A (no)
GR (1) GR3030319T3 (no)
HU (1) HUT74185A (no)
IL (1) IL116387A (no)
NO (1) NO309125B1 (no)
NZ (1) NZ280662A (no)
PL (1) PL311845A1 (no)
RU (1) RU2158259C2 (no)
SI (1) SI0717036T1 (no)
SK (1) SK158195A3 (no)
TW (1) TW381023B (no)
ZA (1) ZA9510693B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2348165A1 (en) * 1998-10-28 2000-05-04 Abbott Laboratories Dihydropyridine compounds and methods of use
EP1377580B1 (en) * 2001-01-30 2006-09-27 Eli Lilly And Company Benzenesulfonic acid indol-5-yl esters as antagonists of the 5-ht6 receptor
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US20050075359A1 (en) * 2003-03-14 2005-04-07 Rikako Kono Large conductance calcium-activated K channel opener
AU2006203819A1 (en) * 2005-01-07 2006-07-13 Roskamp Research Llc Compounds for inhibiting beta-amyloid production and methods of identifying the compounds
WO2013076516A1 (en) * 2011-11-24 2013-05-30 Lipidart Kutató Fejlesztő És Tanácsadó Kft. 1,4- dihydropyridine derivatives with hsp modulating activity
CN103420900B (zh) * 2012-05-22 2015-06-03 中国科学院大连化学物理研究所 一种制备卤代-1,2-二氢吡啶的方法
CN103420901B (zh) * 2012-05-22 2015-06-17 中国科学院大连化学物理研究所 一种制备1,2-二氢吡啶衍生物的方法
CN103804286B (zh) * 2012-11-06 2016-07-06 中国科学院大连化学物理研究所 一种由3-氮杂-1,5-烯炔制备吡啶衍生物的方法
CN103804283B (zh) * 2012-11-06 2016-04-20 中国科学院大连化学物理研究所 一种制备1,2-二氢吡啶衍生物的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966948A (en) 1970-01-24 1976-06-29 Bayer Aktiengesellschaft Spasmolytic, vaso-dilating and anti-hypertensive compositions and methods
DE2018739A1 (en) 1970-04-18 1971-10-28 Farbenfabriken Bayer Ag, 5090 Leverkusen 1,4-dihydro-3,5-diacyl-4-arylpyridines,coronary active
DE2018738A1 (en) 1970-04-18 1971-10-28 Farbenfabriken Bayer Ag, 5090 Leverkusen Hydrogenated pyridines, quinolines andacridi
GB1430961A (en) * 1972-01-22 1976-04-07 Yamanouchi Pharma Co Ltd 1-substituted-1,4-dihyddrypyridine derivatives
FR2649395B1 (fr) * 1989-07-04 1992-11-06 Adir Nouveau derive de la dihydro-1,4 pyridine denomme (-) Ÿi1Ÿ(((amino-2 ethoxy)-2 ethoxy) methylŸi1Ÿ) -2 (dichloro-2,3 phenyl)-4 ethoxycarbonyl-3 methoxycarbonyl-5 methyl-6 dihydro-1,4 pyridine, son procede de preparation et les compositions qui le contiennent
US5446057A (en) * 1993-09-24 1995-08-29 Warner-Lambert Company Substituted tetrahydropyridine and piperidine carboxylic acids as muscarinic antagonists
JP3709997B2 (ja) * 1994-03-29 2005-10-26 日東電工株式会社 耐熱性ネガ型フォトレジスト組成物および感光性基材、ならびにネガ型パターン形成方法

Also Published As

Publication number Publication date
ES2130506T3 (es) 1999-07-01
SI0717036T1 (en) 1999-06-30
CA2165130A1 (en) 1996-06-17
KR960022464A (ko) 1996-07-18
PL311845A1 (en) 1996-06-24
CZ332995A3 (en) 1996-07-17
US5646166A (en) 1997-07-08
NO955104D0 (no) 1995-12-15
DE4444864A1 (de) 1996-06-20
DE59505373D1 (de) 1999-04-22
GR3030319T3 (en) 1999-09-30
FI956015A (fi) 1996-06-17
HU9503592D0 (en) 1996-02-28
AU704466B2 (en) 1999-04-22
IL116387A (en) 2000-11-21
NZ280662A (en) 1997-02-24
EE9500075A (et) 1996-06-17
IL116387A0 (en) 1996-03-31
JPH08239364A (ja) 1996-09-17
AU4029395A (en) 1996-06-27
CN1130505A (zh) 1996-09-11
US5942526A (en) 1999-08-24
EP0717036A1 (de) 1996-06-19
DK0717036T3 (da) 1999-10-11
ZA9510693B (en) 1996-07-03
SK158195A3 (en) 1996-09-04
RU2158259C2 (ru) 2000-10-27
HUT74185A (en) 1996-11-28
ATE177735T1 (de) 1999-04-15
FI956015A0 (fi) 1995-12-14
TW381023B (en) 2000-02-01
NO309125B1 (no) 2000-12-18
EP0717036B1 (de) 1999-03-17

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Free format text: LAPSED IN JUNE 2002