PT856002E - Feniloxazolidinonas com uma ligacao c-c a aneis heterociclicos de 4 a 8 membros - Google Patents

Feniloxazolidinonas com uma ligacao c-c a aneis heterociclicos de 4 a 8 membros

Info

Publication number
PT856002E
PT856002E PT96927316T PT96927316T PT856002E PT 856002 E PT856002 E PT 856002E PT 96927316 T PT96927316 T PT 96927316T PT 96927316 T PT96927316 T PT 96927316T PT 856002 E PT856002 E PT 856002E
Authority
PT
Portugal
Prior art keywords
alkyl
halo
aryl
methyl
substd
Prior art date
Application number
PT96927316T
Other languages
English (en)
Inventor
Michael Roberto Barbachyn
Michael D Ennis
Douglas K Hutchinson
Robert L Hoffman
Richard C Thomas
Toni-Jo Poel
Steven J Brickner
David J Anderson
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21704418&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT856002(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of PT856002E publication Critical patent/PT856002E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT96927316T 1995-09-01 1996-08-13 Feniloxazolidinonas com uma ligacao c-c a aneis heterociclicos de 4 a 8 membros PT856002E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US314995P 1995-09-01 1995-09-01

Publications (1)

Publication Number Publication Date
PT856002E true PT856002E (pt) 2002-04-29

Family

ID=21704418

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96927316T PT856002E (pt) 1995-09-01 1996-08-13 Feniloxazolidinonas com uma ligacao c-c a aneis heterociclicos de 4 a 8 membros

Country Status (26)

Country Link
US (7) US5968962A (pt)
EP (1) EP0856002B1 (pt)
JP (1) JPH11512386A (pt)
KR (1) KR100463772B1 (pt)
CN (1) CN1072222C (pt)
AT (1) ATE207487T1 (pt)
AU (1) AU716493B2 (pt)
BR (1) BR9610474A (pt)
CA (1) CA2228647A1 (pt)
CZ (1) CZ49398A3 (pt)
DE (1) DE69616366T2 (pt)
DK (1) DK0856002T3 (pt)
ES (1) ES2165516T3 (pt)
FI (1) FI980452A7 (pt)
HU (1) HUP9901979A3 (pt)
MX (1) MX9801578A (pt)
NO (1) NO311520B1 (pt)
NZ (1) NZ315469A (pt)
PL (1) PL186524B1 (pt)
PT (1) PT856002E (pt)
RU (1) RU2175324C2 (pt)
SK (1) SK283487B6 (pt)
TW (1) TW419468B (pt)
UA (1) UA52620C2 (pt)
WO (1) WO1997009328A1 (pt)
ZA (1) ZA966935B (pt)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1072222C (zh) * 1995-09-01 2001-10-03 法玛西雅厄普约翰公司 以c－c键连接于4－8元杂环环的苯基噁唑烷酮
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
CA2288750A1 (en) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
JP2002513424A (ja) * 1997-07-11 2002-05-08 ファルマシア・アンド・アップジョン・カンパニー チアジアゾリルおよびオキサジアゾリルフェニルオキサゾリジノン抗菌剤
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US6083967A (en) * 1997-12-05 2000-07-04 Pharmacia & Upjohn Company S-oxide and S,S-dioxide tetrahydrothiopyran phenyloxazolidinones
RU2205832C2 (ru) * 1997-12-05 2003-06-10 Фармация Энд Апджон Компани S-оксидо- и s,s-диоксидотетрагидротиопиранфенилоксазолидиноны и способ их тестирования
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6239152B1 (en) 1998-01-23 2001-05-29 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
CN1311787A (zh) * 1998-06-05 2001-09-05 阿斯特拉曾尼卡有限公司 噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物
ES2241920T3 (es) * 1999-02-01 2005-11-01 PHARMACIA & UPJOHN COMPANY LLC Derivados de 2-fluoro-(oxido-tiopiran-4-il)benceno.
EP1229033B8 (en) * 1999-02-01 2005-06-15 Pharmacia & Upjohn Company LLC 2-Fluoro-(oxid-thiopyran-4-yl)benzene derivatives
MY120189A (en) * 1999-11-04 2005-09-30 Upjohn Co Sultam and sultone derived oxazolidinones
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
HUP0203869A2 (hu) * 1999-12-21 2003-07-28 Pharmacia & Upjohn Co. Szulfoximin funkcionalitással rendelkező oxazolidinok és alkalmazásuk mikrobaellenes szerként, a vegyületeket tartalmazó gyógyszerkészítmények
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
MY127336A (en) * 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
PE20020044A1 (es) 2000-06-16 2002-01-30 Upjohn Co Tiazina oxazolidinona
WO2002002095A2 (en) 2000-06-30 2002-01-10 Pharmacia & Upjohn Company Compositions for treating bacterial infections containing oxazolidinone compound, sulbactam and an ampicillin
US20050032861A1 (en) * 2001-04-07 2005-02-10 Betts Michael John Oxazolidines containing a sulfonimid group as antibiotics
GB0108764D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
NZ528996A (en) * 2001-04-20 2006-01-27 Upjohn Co Process to prepare oxazolidinones
EP1379509A1 (en) 2001-04-20 2004-01-14 PHARMACIA & UPJOHN COMPANY A method for the preparation of oxazolidinones
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
JP2005520782A (ja) * 2001-07-12 2005-07-14 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 向上した水溶解度を有するアミド含有化合物およびアミド含有化合物の水溶解度を向上させる方法
US7125568B2 (en) 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
WO2003062231A1 (en) * 2002-01-24 2003-07-31 Pharmacia & Upjohn Company Antimicrobial dihydrothiazine and dihydrothiopyran oxazolidinones
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
US7141588B2 (en) 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
IL164195A0 (en) * 2002-03-29 2005-12-18 Upjohn Co Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
WO2003097640A1 (en) * 2002-05-22 2003-11-27 Orchid Chemicals & Pharmaceuticals Ltd. Oxazolidinone derivatives as antibacterial agents
TW200404069A (en) * 2002-06-28 2004-03-16 Upjohn Co Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
DE60304360T2 (de) 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate
US7141570B2 (en) * 2002-11-21 2006-11-28 Pharmacia & Upjohn Company N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
DE10300111A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
JP2006516991A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤
JP2006516989A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
WO2004099199A1 (en) * 2003-05-06 2004-11-18 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
WO2004113329A1 (en) * 2003-06-20 2004-12-29 Orchid Chemicals And Pharmaceuticals Ltd. Oxazole derivatives as antibacterial agents
US7304050B2 (en) 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
US7265140B2 (en) 2003-09-23 2007-09-04 Pfizer Inc Acyloxymethylcarbamate prodrugs of oxazolidinones
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
WO2005082892A2 (en) * 2004-02-17 2005-09-09 Dr. Reddy's Laboratories Ltd. Triazole compounds as antibacterial agents and pharmaceutical compositions containing them
BRPI0513083A (pt) * 2004-08-06 2008-04-22 Pharmacia & Upjohn Co Llc oxazolidinonas contendo oxindóis como agentes antibacterianos
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
EP1745784A1 (en) * 2005-06-27 2007-01-24 Ferrer Internacional, S.A. Oxazolidinone derivatives and use thereof as antibiotics
DE102005045518A1 (de) 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
CA2823159C (en) 2005-10-04 2014-10-21 Bayer Intellectual Property Gmbh Polymorphic form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
EP2181993A1 (en) 2006-03-31 2010-05-05 Research Foundation Itsuu Laboratory Antimicrobial oxazolidinone derivatives
US7875958B2 (en) * 2006-09-27 2011-01-25 Taiwan Semiconductor Manufacturing Company, Ltd. Quantum tunneling devices and circuits with lattice-mismatched semiconductor structures
WO2008143649A2 (en) * 2006-12-04 2008-11-27 Dr. Reddy's Laboratories Limited Novel oxazolidinone compounds as antiinfective agents
US7978614B2 (en) * 2007-01-11 2011-07-12 Foundry Network, LLC Techniques for detecting non-receipt of fault detection protocol packets
CL2008001003A1 (es) * 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
CN101883768A (zh) 2007-10-02 2010-11-10 财团法人乙卯研究所 具有7元杂环的噁唑烷酮衍生物
KR101023174B1 (ko) * 2008-09-24 2011-03-18 주식회사 레고켐 바이오사이언스 사이클릭 아미독심 또는 사이클릭 아미드라존 기를 가지는 신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물
KR20110092309A (ko) 2008-11-20 2011-08-17 파나세아 바이오테크 리미티드 신규 항균제
AU2011300365A1 (en) * 2010-09-07 2013-05-02 Symed Labs Limited Processes for the preparation of 4-{4-[5(S)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl} morpholin-3-one
AR093396A1 (es) * 2012-11-09 2015-06-03 Syngenta Participations Ag Derivados de dihidrotiofeno como compuestos insecticidas
EP3914587A4 (en) * 2019-01-18 2022-11-23 Merck Sharp & Dohme LLC OXAZOLIDINONE COMPOUNDS AND USES THEREOF AS ANTIBACTERIAL AGENTS
JP2024522718A (ja) 2021-06-16 2024-06-21 セルジーン コーポレーション 神経変性疾患の治療のための、カルボン酸基を含むアゼチジニル化合物
CN115724823B (zh) * 2021-08-27 2023-11-24 中国科学院大连化学物理研究所 一种制备二氢噻吩衍生物的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1250538A (pt) * 1969-03-18 1971-10-20
FR2356422A1 (fr) * 1976-03-01 1978-01-27 Delalande Sa Nouveaux hydroxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR2380780A2 (fr) * 1977-02-22 1978-09-15 Delalande Sa Application en therapeutique des hydroxymethyl-5 oxazolidinones-2, notamment comme antidepresseurs
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
JPS59118721A (ja) * 1982-12-25 1984-07-09 Nippon Zeon Co Ltd カルボキシル化合物の製造方法
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
DE3544601A1 (de) * 1984-12-18 1986-06-19 C.S. Kaseihin Co. Inc., Tokio/Tokyo Verfahren zur herstellung von siliciumhaltigen isocyanatverbindungen
US5130316A (en) * 1988-07-29 1992-07-14 Du Pont Merck Pharmaceutical Company Aminomethyloxooxazlidinyl arylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5254577A (en) * 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
ATE146783T1 (de) * 1991-11-01 1997-01-15 Upjohn Co Substituierte aryl- und heteroaryl- phenyloxazolidinone
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5668286A (en) * 1994-03-15 1997-09-16 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
CN1072222C (zh) * 1995-09-01 2001-10-03 法玛西雅厄普约翰公司 以c－c键连接于4－8元杂环环的苯基噁唑烷酮
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
CA2288750A1 (en) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9717807D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
ES2241920T3 (es) * 1999-02-01 2005-11-01 PHARMACIA & UPJOHN COMPANY LLC Derivados de 2-fluoro-(oxido-tiopiran-4-il)benceno.
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents

Also Published As

Publication number Publication date
BR9610474A (pt) 1999-03-02
DE69616366T2 (de) 2002-07-04
SK283487B6 (sk) 2003-08-05
CN1072222C (zh) 2001-10-03
AU6718196A (en) 1997-03-27
NZ315469A (en) 2000-01-28
ATE207487T1 (de) 2001-11-15
TW419468B (en) 2001-01-21
DK0856002T3 (da) 2002-02-11
FI980452L (fi) 1998-02-27
PL186524B1 (pl) 2004-01-30
HUP9901979A2 (hu) 2000-02-28
FI980452A0 (fi) 1998-02-27
KR19990044238A (ko) 1999-06-25
US5968962A (en) 1999-10-19
SK19598A3 (en) 1998-11-04
CZ49398A3 (cs) 1998-08-12
KR100463772B1 (ko) 2005-11-09
ZA966935B (en) 1998-02-16
WO1997009328A1 (en) 1997-03-13
UA52620C2 (uk) 2003-01-15
ES2165516T3 (es) 2002-03-16
DE69616366D1 (de) 2001-11-29
US6043266A (en) 2000-03-28
NO980855D0 (no) 1998-02-27
RU2175324C2 (ru) 2001-10-27
FI980452A7 (fi) 1998-02-27
US6166056A (en) 2000-12-26
NO311520B1 (no) 2001-12-03
AU716493B2 (en) 2000-02-24
CA2228647A1 (en) 1997-03-13
NO980855L (no) 1998-04-30
HK1014946A1 (en) 1999-10-08
HUP9901979A3 (en) 2000-03-28
US6358942B1 (en) 2002-03-19
JPH11512386A (ja) 1999-10-26
MX9801578A (es) 1998-08-30
US6313307B1 (en) 2001-11-06
EP0856002A1 (en) 1998-08-05
US6051716A (en) 2000-04-18
CN1197457A (zh) 1998-10-28
US20050054683A1 (en) 2005-03-10
EP0856002B1 (en) 2001-10-24
PL325152A1 (en) 1998-07-06

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