HK1251592A1 - 與多分子的抗原重複結合的抗原結合分子 - Google Patents

與多分子的抗原重複結合的抗原結合分子

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Publication number
HK1251592A1
HK1251592A1 HK18111105.9A HK18111105A HK1251592A1 HK 1251592 A1 HK1251592 A1 HK 1251592A1 HK 18111105 A HK18111105 A HK 18111105A HK 1251592 A1 HK1251592 A1 HK 1251592A1
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HK
Hong Kong
Prior art keywords
antigen
binding
molecule capable
binding molecule
molecules repeatedly
Prior art date
Application number
HK18111105.9A
Other languages
English (en)
Inventor
井川智之
石井慎也
舩木美步
廣庭奈緒香
前田敦彥
根津淳一
類家慶直
馬場威
清水駿
Original Assignee
中外制藥株式會社
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Filing date
Publication date
Application filed by 中外制藥株式會社 filed Critical 中外制藥株式會社
Publication of HK1251592A1 publication Critical patent/HK1251592A1/zh

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007Carcino-embryonic Antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C07ORGANIC CHEMISTRY
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    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
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    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/248IL-6
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/4283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
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    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
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    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/5375Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

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HK18111105.9A 2010-11-30 2013-12-05 與多分子的抗原重複結合的抗原結合分子 HK1251592A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010266121 2010-11-30
JP2011217886 2011-09-30

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HK1251592A1 true HK1251592A1 (zh) 2019-02-01

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HK19100448.7A HK1258068A1 (zh) 2010-11-30 2013-12-05 與多分子的抗原重複結合的抗原結合分子
HK18111105.9A HK1251592A1 (zh) 2010-11-30 2013-12-05 與多分子的抗原重複結合的抗原結合分子

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US (3) US20140234340A1 (zh)
EP (2) EP4231014A3 (zh)
JP (5) JP6030452B2 (zh)
KR (2) KR102385507B1 (zh)
CN (3) CN108715614A (zh)
AU (1) AU2011337704B2 (zh)
BR (1) BR112013013354A2 (zh)
CA (1) CA2819356C (zh)
HK (2) HK1258068A1 (zh)
MX (2) MX365235B (zh)
RU (3) RU2658504C9 (zh)
SG (2) SG10201509790YA (zh)
TW (5) TWI654204B (zh)
WO (1) WO2012073992A1 (zh)

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