UA83791C2 - Антитело против vla-1, фармацевтическая композиция, которая его содержит, и из применение для лечения индивидуума с иммунологическим расстройством, опосредованным vla-1 - Google Patents

Антитело против vla-1, фармацевтическая композиция, которая его содержит, и из применение для лечения индивидуума с иммунологическим расстройством, опосредованным vla-1

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Publication number
UA83791C2
UA83791C2 UA20031110207A UA20031110207A UA83791C2 UA 83791 C2 UA83791 C2 UA 83791C2 UA 20031110207 A UA20031110207 A UA 20031110207A UA 20031110207 A UA20031110207 A UA 20031110207A UA 83791 C2 UA83791 C2 UA 83791C2
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Ukraine
Prior art keywords
vla
mediated
antibody
pharmaceutical composition
immunological disorder
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UA20031110207A
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English (en)
Ukrainian (uk)
Inventor
Пол Д. Лайн
Эллен А. Гарбер
Хосе В. Салдана
Майкл Карпусас
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Байоджен Айдек Ма Инк.
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Application filed by Байоджен Айдек Ма Инк. filed Critical Байоджен Айдек Ма Инк.
Publication of UA83791C2 publication Critical patent/UA83791C2/ru

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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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Abstract

Изобретение относится к антителу против интегрина VLA-1, которое имеет уникальные гипервариабельные участки (CDR), выделенной последовательности нуклеиновой кислоты, которая его кодирует, вектору, клетки гибридомы и клетке клеточной линии, фармацевтической композиции, способу лечения индивидуума с иммунологическим расстройством, опосредованным VLA-1, способу определения уровня VLA-1 в ткани. Изобретение также относится к химерному и гуманизированному антителу против VLA-1.
UA20031110207A 2001-04-13 2002-04-12 Антитело против vla-1, фармацевтическая композиция, которая его содержит, и из применение для лечения индивидуума с иммунологическим расстройством, опосредованным vla-1 UA83791C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28379401P 2001-04-13 2001-04-13
US30368901P 2001-07-06 2001-07-06
PCT/US2002/011521 WO2002083854A2 (en) 2001-04-13 2002-04-12 Antibodies to vla-1

Publications (1)

Publication Number Publication Date
UA83791C2 true UA83791C2 (ru) 2008-08-26

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UA20031110207A UA83791C2 (ru) 2001-04-13 2002-04-12 Антитело против vla-1, фармацевтическая композиция, которая его содержит, и из применение для лечения индивидуума с иммунологическим расстройством, опосредованным vla-1

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US (7) US7358054B2 (ru)
EP (1) EP1423431B1 (ru)
JP (2) JP4303475B2 (ru)
KR (1) KR100927670B1 (ru)
CN (1) CN1561345B (ru)
AR (1) AR036330A1 (ru)
AT (1) ATE471344T1 (ru)
AU (1) AU2002258778C1 (ru)
BG (1) BG66334B1 (ru)
BR (1) BRPI0209792B8 (ru)
CA (1) CA2443903C (ru)
CZ (1) CZ303450B6 (ru)
DE (1) DE60236735D1 (ru)
EA (1) EA006705B1 (ru)
EE (1) EE200300509A (ru)
ES (1) ES2347532T3 (ru)
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HU (1) HUP0402250A3 (ru)
IL (3) IL158376A0 (ru)
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MX (1) MXPA03009390A (ru)
MY (1) MY138286A (ru)
NO (1) NO20034554L (ru)
NZ (1) NZ529494A (ru)
PL (1) PL367324A1 (ru)
SK (1) SK288124B6 (ru)
UA (1) UA83791C2 (ru)
WO (1) WO2002083854A2 (ru)
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