SG11202009010RA - Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use - Google Patents

Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use

Info

Publication number
SG11202009010RA
SG11202009010RA SG11202009010RA SG11202009010RA SG11202009010RA SG 11202009010R A SG11202009010R A SG 11202009010RA SG 11202009010R A SG11202009010R A SG 11202009010RA SG 11202009010R A SG11202009010R A SG 11202009010RA SG 11202009010R A SG11202009010R A SG 11202009010RA
Authority
SG
Singapore
Prior art keywords
reactivity
methods
cross
virus
antibodies
Prior art date
Application number
SG11202009010RA
Inventor
Katja Fink
Cheng-I Wang
Lisa Fong Poh Ng
Laurent Renia
Zenjiro Sampei
Xing'er Christine Koo
Original Assignee
Chugai Pharmaceutical Co Ltd
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Agency Science Tech & Res filed Critical Chugai Pharmaceutical Co Ltd
Publication of SG11202009010RA publication Critical patent/SG11202009010RA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
SG11202009010RA 2018-03-15 2019-03-15 Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use SG11202009010RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201802164Y 2018-03-15
PCT/SG2019/050145 WO2019177543A1 (en) 2018-03-15 2019-03-15 Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use

Publications (1)

Publication Number Publication Date
SG11202009010RA true SG11202009010RA (en) 2020-10-29

Family

ID=67908433

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009010RA SG11202009010RA (en) 2018-03-15 2019-03-15 Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use

Country Status (13)

Country Link
US (1) US11891432B2 (en)
EP (1) EP3765494A4 (en)
JP (1) JP2021518343A (en)
KR (1) KR20200132938A (en)
CN (2) CN112119090B (en)
CA (1) CA3093729A1 (en)
IL (1) IL277375A (en)
MX (1) MX2020009296A (en)
PH (1) PH12020551492A1 (en)
SG (1) SG11202009010RA (en)
TW (1) TWI827585B (en)
WO (1) WO2019177543A1 (en)
ZA (1) ZA202005662B (en)

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MX2010003450A (en) 2007-09-26 2010-04-27 Chugai Pharmaceutical Co Ltd Modified antibody constant region.
CN114773470A (en) 2015-02-05 2022-07-22 中外制药株式会社 Antibodies comprising an ion concentration-dependent antigen-binding domain, FC region variants, IL-8-binding antibodies and uses thereof
CN116271014A (en) 2016-08-05 2023-06-23 中外制药株式会社 Compositions for preventing or treating IL-8 related diseases
CN116096415A (en) * 2020-08-14 2023-05-09 中外制药株式会社 Single-armed antigen binding molecules and uses thereof
CN114410588B (en) * 2022-01-29 2022-11-04 西安电子科技大学 Alpha 1 beta 1 integrin-dependent enhanced CAR macrophage and preparation method and application thereof
WO2024036265A2 (en) * 2022-08-12 2024-02-15 Takeda Vaccines, Inc. Novel anti-denv3 antibodies

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