BR112016002198A2 - métodos de tratamento de miosite por corpos de inclusão esporádica - Google Patents
métodos de tratamento de miosite por corpos de inclusão esporádicaInfo
- Publication number
- BR112016002198A2 BR112016002198A2 BR112016002198A BR112016002198A BR112016002198A2 BR 112016002198 A2 BR112016002198 A2 BR 112016002198A2 BR 112016002198 A BR112016002198 A BR 112016002198A BR 112016002198 A BR112016002198 A BR 112016002198A BR 112016002198 A2 BR112016002198 A2 BR 112016002198A2
- Authority
- BR
- Brazil
- Prior art keywords
- inclusion body
- body myositis
- methods
- sporadic inclusion
- antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Abstract
a presente invenção refere-se ao tratamento de miosite por corpos de inclusão esporádica e outros transtornos de desgaste mus-cular com novos regimes, o qual emprega uma quantidade terapeuti-camente eficaz de um antagonista de miostatina, por exemplo, uma molécula de ligação com miostatina, por exemplo, um anticorpo de mi-ostatina ou uma molécula de ligação com receptor actrii, um anticorpo de receptor actrii, tal como o anticorpo de bimagrumab.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361865861P | 2013-08-14 | 2013-08-14 | |
US201461983567P | 2014-04-24 | 2014-04-24 | |
PCT/IB2014/063904 WO2015022658A2 (en) | 2013-08-14 | 2014-08-13 | Methods of treating sporadic inclusion body myositis |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112016002198A2 true BR112016002198A2 (pt) | 2017-09-12 |
Family
ID=51492992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016002198A BR112016002198A2 (pt) | 2013-08-14 | 2014-08-13 | métodos de tratamento de miosite por corpos de inclusão esporádica |
Country Status (18)
Country | Link |
---|---|
US (2) | US20160200818A1 (pt) |
EP (1) | EP3033358A2 (pt) |
JP (1) | JP2016528247A (pt) |
KR (1) | KR20160042987A (pt) |
CN (1) | CN105960414A (pt) |
AU (2) | AU2014307589A1 (pt) |
BR (1) | BR112016002198A2 (pt) |
CA (1) | CA2918300A1 (pt) |
CL (1) | CL2016000341A1 (pt) |
HK (1) | HK1219280A1 (pt) |
IL (1) | IL243883A0 (pt) |
MX (1) | MX2016001969A (pt) |
PH (1) | PH12016500141A1 (pt) |
RU (1) | RU2016108652A (pt) |
SG (2) | SG11201600212VA (pt) |
TN (1) | TN2016000057A1 (pt) |
TW (1) | TW201536318A (pt) |
WO (1) | WO2015022658A2 (pt) |
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IN2014DN10515A (pt) | 2006-03-31 | 2015-08-21 | Chugai Pharmaceutical Co Ltd | |
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BRPI0806861A2 (pt) | 2007-02-01 | 2014-08-05 | Acceleron Pharma Inc | Antagonistas de ativina-actriia e usos para tratar ou prevenir câncer de mama |
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BRPI0807506B1 (pt) | 2007-02-09 | 2022-02-15 | Acceleron Pharma, Inc | Uso de uma proteína de fusão actriia-fc para a fabricação de um medicamento para tratar ou previnir mieloma múltiplo |
CN103877564A (zh) | 2007-09-18 | 2014-06-25 | 阿塞勒隆制药公司 | 活化素-actriia拮抗剂和减少或抑制fsh分泌的用途 |
CA2700701C (en) | 2007-09-26 | 2020-12-29 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in cdr |
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DK2780368T3 (en) | 2011-11-14 | 2018-02-05 | Regeneron Pharma | COMPOSITIONS AND PROCEDURES FOR INCREASING MUSCLE MASS AND MUSCLE STRENGTH BY SPECIFIC ANTAGONIZATION OF GDF8 AND / OR ACTIVIN A |
DK2889377T3 (da) | 2012-08-24 | 2020-03-30 | Chugai Pharmaceutical Co Ltd | Fc?RIIb-Specifik Fc-regionsvariant |
WO2014030750A1 (ja) | 2012-08-24 | 2014-02-27 | 中外製薬株式会社 | マウスFcγRII特異的Fc抗体 |
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WO2014163101A1 (ja) | 2013-04-02 | 2014-10-09 | 中外製薬株式会社 | Fc領域改変体 |
BR122023023170A2 (pt) | 2014-06-13 | 2024-02-20 | Acceleron Pharma Inc. | Uso de um antagonista de actrii no tratamento ou prevenção de úlcera cutânea associada com beta-talassemia |
RU2017123880A (ru) * | 2014-12-08 | 2019-01-10 | Новартис Аг | Антагонисты миостатина или активина для лечения саркопении |
CR20170326A (es) | 2014-12-19 | 2017-08-22 | Chugai Pharmaceutical Co Ltd | Anticuerpos antimiostatina, polipéptidos que contienen regiones fc variantes, y métodos de uso |
WO2016125495A1 (en) | 2015-02-05 | 2016-08-11 | Chugai Seiyaku Kabushiki Kaisha | Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof |
WO2016168613A1 (en) * | 2015-04-15 | 2016-10-20 | Regeneron Pharmaceuticals, Inc. | Methods of increasing strength and functionality with gdf8 inhibitors |
JP6142069B1 (ja) * | 2015-12-18 | 2017-06-07 | 中外製薬株式会社 | 抗ミオスタチン抗体、変異Fc領域を含むポリペプチド、および使用方法 |
WO2017110981A1 (en) | 2015-12-25 | 2017-06-29 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
KR20230152153A (ko) | 2016-03-10 | 2023-11-02 | 악셀레론 파마 인코포레이티드 | 액티빈 타입 2 수용체 결합 단백질 및 이의 용도 |
KR20230079499A (ko) | 2016-08-05 | 2023-06-07 | 추가이 세이야쿠 가부시키가이샤 | Il-8 관련 질환의 치료용 또는 예방용 조성물 |
WO2018175460A1 (en) * | 2017-03-24 | 2018-09-27 | Novartis Ag | Methods for preventing and treating heart disease |
WO2019003104A1 (en) * | 2017-06-28 | 2019-01-03 | Novartis Ag | METHOD FOR PREVENTING AND TREATING URINARY INCONTINENCE |
EA202092064A1 (ru) | 2018-03-01 | 2020-12-21 | Ридженерон Фармасьютикалз, Инк. | Способы изменения состава тела |
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-
2014
- 2014-08-13 TN TN2016000057A patent/TN2016000057A1/en unknown
- 2014-08-13 MX MX2016001969A patent/MX2016001969A/es unknown
- 2014-08-13 BR BR112016002198A patent/BR112016002198A2/pt not_active IP Right Cessation
- 2014-08-13 SG SG11201600212VA patent/SG11201600212VA/en unknown
- 2014-08-13 AU AU2014307589A patent/AU2014307589A1/en not_active Abandoned
- 2014-08-13 KR KR1020167006266A patent/KR20160042987A/ko not_active Application Discontinuation
- 2014-08-13 WO PCT/IB2014/063904 patent/WO2015022658A2/en active Application Filing
- 2014-08-13 SG SG10201801063TA patent/SG10201801063TA/en unknown
- 2014-08-13 JP JP2016533986A patent/JP2016528247A/ja active Pending
- 2014-08-13 CN CN201480056363.5A patent/CN105960414A/zh not_active Withdrawn
- 2014-08-13 TW TW103127832A patent/TW201536318A/zh unknown
- 2014-08-13 US US14/911,333 patent/US20160200818A1/en not_active Abandoned
- 2014-08-13 RU RU2016108652A patent/RU2016108652A/ru not_active Application Discontinuation
- 2014-08-13 EP EP14761413.5A patent/EP3033358A2/en not_active Ceased
- 2014-08-13 CA CA2918300A patent/CA2918300A1/en not_active Abandoned
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2016
- 2016-01-21 PH PH12016500141A patent/PH12016500141A1/en unknown
- 2016-02-01 IL IL243883A patent/IL243883A0/en unknown
- 2016-02-12 CL CL2016000341A patent/CL2016000341A1/es unknown
- 2016-06-22 HK HK16107243.2A patent/HK1219280A1/zh unknown
-
2017
- 2017-09-13 AU AU2017228600A patent/AU2017228600A1/en not_active Abandoned
- 2017-09-28 US US15/718,091 patent/US20180066061A1/en not_active Abandoned
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HK1219280A1 (zh) | 2017-03-31 |
TN2016000057A1 (en) | 2017-07-05 |
US20160200818A1 (en) | 2016-07-14 |
AU2014307589A1 (en) | 2016-02-11 |
CA2918300A1 (en) | 2015-02-19 |
AU2017228600A1 (en) | 2017-10-05 |
CL2016000341A1 (es) | 2016-10-28 |
US20180066061A1 (en) | 2018-03-08 |
TW201536318A (zh) | 2015-10-01 |
EP3033358A2 (en) | 2016-06-22 |
RU2016108652A (ru) | 2017-09-14 |
WO2015022658A3 (en) | 2015-05-28 |
JP2016528247A (ja) | 2016-09-15 |
SG10201801063TA (en) | 2018-04-27 |
KR20160042987A (ko) | 2016-04-20 |
PH12016500141A1 (en) | 2016-04-18 |
IL243883A0 (en) | 2016-04-21 |
WO2015022658A2 (en) | 2015-02-19 |
CN105960414A (zh) | 2016-09-21 |
RU2016108652A3 (pt) | 2018-04-28 |
SG11201600212VA (en) | 2016-02-26 |
MX2016001969A (es) | 2016-06-02 |
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