CL2016000341A1 - Métodos para tratar la miositis por cuerpos de inclusión esporádica - Google Patents
Métodos para tratar la miositis por cuerpos de inclusión esporádicaInfo
- Publication number
- CL2016000341A1 CL2016000341A1 CL2016000341A CL2016000341A CL2016000341A1 CL 2016000341 A1 CL2016000341 A1 CL 2016000341A1 CL 2016000341 A CL2016000341 A CL 2016000341A CL 2016000341 A CL2016000341 A CL 2016000341A CL 2016000341 A1 CL2016000341 A1 CL 2016000341A1
- Authority
- CL
- Chile
- Prior art keywords
- methods
- inclusion bodies
- sporadic inclusion
- myositis
- treat
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epidemiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
Abstract
Métodos para tratar la miositis por cuerpos de inclusión esporadica que comprende el uso de un antagonista de miostatina, que es un antagonista del receptor ActRII. El antagonista es un anticuerpo, que puede ser Bimagrumab.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361865861P | 2013-08-14 | 2013-08-14 | |
US201461983567P | 2014-04-24 | 2014-04-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2016000341A1 true CL2016000341A1 (es) | 2016-10-28 |
Family
ID=51492992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2016000341A CL2016000341A1 (es) | 2013-08-14 | 2016-02-12 | Métodos para tratar la miositis por cuerpos de inclusión esporádica |
Country Status (18)
Country | Link |
---|---|
US (2) | US20160200818A1 (es) |
EP (1) | EP3033358A2 (es) |
JP (1) | JP2016528247A (es) |
KR (1) | KR20160042987A (es) |
CN (1) | CN105960414A (es) |
AU (2) | AU2014307589A1 (es) |
BR (1) | BR112016002198A2 (es) |
CA (1) | CA2918300A1 (es) |
CL (1) | CL2016000341A1 (es) |
HK (1) | HK1219280A1 (es) |
IL (1) | IL243883A0 (es) |
MX (1) | MX2016001969A (es) |
PH (1) | PH12016500141A1 (es) |
RU (1) | RU2016108652A (es) |
SG (2) | SG11201600212VA (es) |
TN (1) | TN2016000057A1 (es) |
TW (1) | TW201536318A (es) |
WO (1) | WO2015022658A2 (es) |
Families Citing this family (36)
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CN103432568A (zh) | 2005-11-23 | 2013-12-11 | 阿塞勒隆制药公司 | Activin-ActRIIa拮抗剂及其促进骨骼生长的应用 |
US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
US11046784B2 (en) | 2006-03-31 | 2021-06-29 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
MX2009008222A (es) | 2007-02-01 | 2009-10-12 | Acceleron Pharma Inc | Antagonistas de activina-actriia y usos para tratar o prevenir cancer de mama. |
TW202021980A (zh) | 2007-02-02 | 2020-06-16 | 美商艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
KR20200054317A (ko) | 2007-02-09 | 2020-05-19 | 악셀레론 파마 인코포레이티드 | 액티빈-ActRⅡA 길항제 및 암 환자에서 골 생장을 촉진시키기 위한 이의 용도 |
CN103877564A (zh) | 2007-09-18 | 2014-06-25 | 阿塞勒隆制药公司 | 活化素-actriia拮抗剂和减少或抑制fsh分泌的用途 |
MX369784B (es) | 2007-09-26 | 2019-11-21 | Chugai Pharmaceutical Co Ltd | Metodo de modificacion del punto isoelectrico de anticuerpos mediante la sustitucion de aminoacidos en region de determinacion de complementariedad (cdr). |
DK2708559T3 (en) | 2008-04-11 | 2018-06-14 | Chugai Pharmaceutical Co Ltd | Antigen-binding molecule capable of repeatedly binding two or more antigen molecules |
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TW201919685A (zh) | 2008-08-14 | 2019-06-01 | 美商艾瑟勒朗法瑪公司 | 使用gdf阱以增加紅血球水平 |
AU2010263182B2 (en) | 2009-06-12 | 2016-05-12 | Acceleron Pharma Inc. | Truncated ActRIIB-Fc fusion proteins |
US8710016B2 (en) | 2009-11-17 | 2014-04-29 | Acceleron Pharma, Inc. | ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy |
WO2012064771A1 (en) | 2010-11-08 | 2012-05-18 | Acceleron Pharma, Inc. | Actriia binding agents and uses thereof |
CN108715614A (zh) | 2010-11-30 | 2018-10-30 | 中外制药株式会社 | 与多分子的抗原重复结合的抗原结合分子 |
AU2012339722B2 (en) | 2011-11-14 | 2017-09-14 | Regeneron Pharmaceuticals, Inc. | Compositions and methods for increasing muscle mass and muscle strength by specifically antagonizing GDF8 and/or Activin A |
CA2882272C (en) | 2012-08-24 | 2023-08-29 | Chugai Seiyaku Kabushiki Kaisha | Fc.gamma.riib-specific fc region variant |
EP3597747B1 (en) | 2012-08-24 | 2023-03-15 | Chugai Seiyaku Kabushiki Kaisha | Mouse fcgammarii-specific fc antibody |
KR102279522B1 (ko) | 2012-11-02 | 2021-07-19 | 셀진 코포레이션 | 골 및 다른 장애를 치료하기 위한 액티빈-actrii 길항제 및 용도 |
AU2014250434B2 (en) | 2013-04-02 | 2019-08-08 | Chugai Seiyaku Kabushiki Kaisha | Fc region variant |
TN2016000553A1 (en) | 2014-06-13 | 2018-04-04 | Acceleron Pharma Inc | Methods and compositions for treating ulcers |
CN106999589A (zh) * | 2014-12-08 | 2017-08-01 | 诺华股份有限公司 | 用于治疗肌肉减少症的肌肉生长抑制素或激活素拮抗剂 |
JP6227191B1 (ja) | 2014-12-19 | 2017-11-08 | 中外製薬株式会社 | 抗ミオスタチン抗体、変異Fc領域を含むポリペプチド、および使用方法 |
KR102605798B1 (ko) | 2015-02-05 | 2023-11-23 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용 |
MA49661A (fr) * | 2015-04-15 | 2020-06-03 | Regeneron Pharma | Méthode pour augmenter la résistance et la fonctionnalité avec des inhibiteurs de gdf-8 |
CA3002422C (en) * | 2015-12-18 | 2024-04-16 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use |
JP7141336B2 (ja) | 2015-12-25 | 2022-09-22 | 中外製薬株式会社 | 抗ミオスタチン抗体および使用方法 |
AU2017230091B2 (en) * | 2016-03-10 | 2022-04-07 | Acceleron Pharma Inc. | Activin type 2 receptor binding proteins and uses thereof |
JP6527643B2 (ja) | 2016-08-05 | 2019-06-05 | 中外製薬株式会社 | Il−8関連疾患の治療用又は予防用組成物 |
KR102628323B1 (ko) * | 2017-03-24 | 2024-01-22 | 노바르티스 아게 | 심장질환 예방 및 치료 방법 |
AU2018292579A1 (en) * | 2017-06-28 | 2019-12-05 | Novartis Ag | Methods for preventing and treating urinary incontinence |
CN111787981A (zh) | 2018-03-01 | 2020-10-16 | 瑞泽恩制药公司 | 改变身体组成的方法 |
CN114175082A (zh) * | 2019-07-24 | 2022-03-11 | 索尼集团公司 | 信息处理设备、信息处理方法和信息处理程序 |
KR20230131207A (ko) * | 2021-01-13 | 2023-09-12 | 아스텔라스세이야쿠 가부시키가이샤 | ActRIIA, ActRIIB 및 Fn14에 결합하는 다중 특이성항체 |
WO2024044782A1 (en) * | 2022-08-26 | 2024-02-29 | Versanis Bio, Inc. | Actrii antibody fixed unit dose treatments |
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2014
- 2014-08-13 BR BR112016002198A patent/BR112016002198A2/pt not_active IP Right Cessation
- 2014-08-13 SG SG11201600212VA patent/SG11201600212VA/en unknown
- 2014-08-13 SG SG10201801063TA patent/SG10201801063TA/en unknown
- 2014-08-13 MX MX2016001969A patent/MX2016001969A/es unknown
- 2014-08-13 CN CN201480056363.5A patent/CN105960414A/zh not_active Withdrawn
- 2014-08-13 TW TW103127832A patent/TW201536318A/zh unknown
- 2014-08-13 AU AU2014307589A patent/AU2014307589A1/en not_active Abandoned
- 2014-08-13 CA CA2918300A patent/CA2918300A1/en not_active Abandoned
- 2014-08-13 TN TN2016000057A patent/TN2016000057A1/en unknown
- 2014-08-13 EP EP14761413.5A patent/EP3033358A2/en not_active Ceased
- 2014-08-13 US US14/911,333 patent/US20160200818A1/en not_active Abandoned
- 2014-08-13 WO PCT/IB2014/063904 patent/WO2015022658A2/en active Application Filing
- 2014-08-13 RU RU2016108652A patent/RU2016108652A/ru not_active Application Discontinuation
- 2014-08-13 JP JP2016533986A patent/JP2016528247A/ja active Pending
- 2014-08-13 KR KR1020167006266A patent/KR20160042987A/ko not_active Application Discontinuation
-
2016
- 2016-01-21 PH PH12016500141A patent/PH12016500141A1/en unknown
- 2016-02-01 IL IL243883A patent/IL243883A0/en unknown
- 2016-02-12 CL CL2016000341A patent/CL2016000341A1/es unknown
- 2016-06-22 HK HK16107243.2A patent/HK1219280A1/zh unknown
-
2017
- 2017-09-13 AU AU2017228600A patent/AU2017228600A1/en not_active Abandoned
- 2017-09-28 US US15/718,091 patent/US20180066061A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
SG10201801063TA (en) | 2018-04-27 |
US20180066061A1 (en) | 2018-03-08 |
WO2015022658A3 (en) | 2015-05-28 |
AU2014307589A1 (en) | 2016-02-11 |
US20160200818A1 (en) | 2016-07-14 |
AU2017228600A1 (en) | 2017-10-05 |
JP2016528247A (ja) | 2016-09-15 |
CA2918300A1 (en) | 2015-02-19 |
HK1219280A1 (zh) | 2017-03-31 |
RU2016108652A3 (es) | 2018-04-28 |
TN2016000057A1 (en) | 2017-07-05 |
MX2016001969A (es) | 2016-06-02 |
BR112016002198A2 (pt) | 2017-09-12 |
EP3033358A2 (en) | 2016-06-22 |
IL243883A0 (en) | 2016-04-21 |
WO2015022658A2 (en) | 2015-02-19 |
PH12016500141A1 (en) | 2016-04-18 |
KR20160042987A (ko) | 2016-04-20 |
TW201536318A (zh) | 2015-10-01 |
SG11201600212VA (en) | 2016-02-26 |
CN105960414A (zh) | 2016-09-21 |
RU2016108652A (ru) | 2017-09-14 |
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