|
US7605238B2
(en)
*
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
EP1792991A1
(en)
|
1999-08-24 |
2007-06-06 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
TW201305214A
(zh)
|
2000-02-10 |
2013-02-01 |
Abbott Gmbh & Co Kg |
與人類間白素－１８結合之抗體，及其製法及用途
|
|
AU2002231736A1
(en)
|
2000-12-22 |
2002-07-08 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Use of repulsive guidance molecule (rgm) and its modulators
|
|
ME00502B
(me)
|
2001-01-05 |
2011-10-10 |
Amgen Fremont Inc |
Antitjela za insulinu sličan receptor faktora i rasta
|
|
JP4307845B2
(ja)
|
2001-04-26 |
2009-08-05 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
Ｃｒｉｐｔｏをブロックする抗体およびその使用
|
|
JP2005519580A
(ja)
|
2001-05-16 |
2005-07-07 |
アルバート アインシュタイン カレッジ オブ メディシン オブ イエシバ ユニバーシティ |
非ヒト動物由来のヒト抗肺炎球菌抗体
|
|
IL149701A0
(en)
*
|
2001-05-23 |
2002-11-10 |
Pfizer Prod Inc |
Use of anti-ctla-4 antibodies
|
|
BRPI0210579B8
(pt)
|
2001-06-26 |
2021-05-25 |
Amgen Fremont Inc |
anticorpo e composição farmacêutica
|
|
AU2006228095B2
(en)
*
|
2001-10-11 |
2010-11-04 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
US7521053B2
(en)
*
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
ATE435239T1
(de)
|
2002-03-29 |
2009-07-15 |
Schering Corp |
Menschliche monoklonale antikörper gegen interleukin-5 sowie diese umfassende verfahren und zusammensetzungen
|
|
CN1652820A
(zh)
|
2002-04-12 |
2005-08-10 |
梅达雷克斯公司 |
使用ctla－4抗体的治疗方法
|
|
EP1549678A4
(en)
*
|
2002-09-30 |
2006-01-18 |
Pfizer Prod Inc |
HYBRIDOMAS THAT PRODUCE HIGH CONCENTRATIONS OF ANTIBODIES TO THE HUMAN SEQUENCE
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US7465446B2
(en)
|
2003-05-30 |
2008-12-16 |
Medarex, Inc. |
Surrogate therapeutic endpoint for anti-CTLA4-based immunotherapy of disease
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
JP2007528721A
(ja)
|
2003-08-14 |
2007-10-18 |
ダイアックス コーポレイション |
エンドセリアーゼ−２リガンド
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
US20050100965A1
(en)
|
2003-11-12 |
2005-05-12 |
Tariq Ghayur |
IL-18 binding proteins
|
|
ATE501174T1
(de)
|
2004-01-09 |
2011-03-15 |
Pfizer |
Antikörper gegen madcam
|
|
RU2346702C2
(ru)
*
|
2004-03-26 |
2009-02-20 |
Пфайзер Продактс Инк. |
Применение антител к ctla-4
|
|
US7494779B2
(en)
|
2004-06-14 |
2009-02-24 |
Li-Te Chin |
Method for producing human antibodies to human CD152 with properties of agonist, antagonist, or inverse agonist
|
|
WO2006003179A2
(en)
|
2004-07-01 |
2006-01-12 |
Novo Nordisk A/S |
Antibodies binding to receptors kir2dl1, -2, 3 but not kir2ds4 and their therapeutic use
|
|
AU2005264063B2
(en)
|
2004-07-16 |
2009-09-10 |
Pfizer Products Inc. |
Combination treatment for non-hematologic malignancies using an anti-igf-1r antibody
|
|
US7892827B2
(en)
|
2004-11-26 |
2011-02-22 |
Pieris Ag |
Compound with affinity for the cytotoxic T lymphocyte-associated antigen (CTLA-4)
|
|
AU2012200203B2
(en)
*
|
2005-03-08 |
2014-07-03 |
Pfizer Products Inc. |
Anti-CTLA-4 Antibody Compositions
|
|
BRPI0608815B1
(pt)
*
|
2005-03-08 |
2021-10-13 |
Pfizer Products Inc |
Composições de anticorpo anti-ctla-4
|
|
AU2014240252B2
(en)
*
|
2005-03-08 |
2016-10-06 |
Pfizer Products Inc |
Anti-CTLA-4 Antibody Compositions
|
|
JP2006265155A
(ja)
*
|
2005-03-23 |
2006-10-05 |
Link Genomics Kk |
癌の免疫療法
|
|
WO2006101691A1
(en)
*
|
2005-03-23 |
2006-09-28 |
Pfizer Products Inc. |
Therapy of prostate cancer with ctla4 antibodies and hormonal therapy
|
|
ES2432091T5
(es)
|
2005-03-25 |
2022-03-18 |
Gitr Inc |
Moléculas de unión GITR y usos de las mismas
|
|
WO2006116269A2
(en)
|
2005-04-25 |
2006-11-02 |
Pfizer Inc. |
Antibodies to myostatin
|
|
EP2444421A1
(en)
|
2005-04-26 |
2012-04-25 |
Pfizer Inc. |
P-Cadherin antibodies
|
|
JP5224707B2
(ja)
*
|
2005-04-28 |
2013-07-03 |
持田製薬株式会社 |
抗血小板膜糖蛋白質ｖｉモノクローナル抗体
|
|
US20090041783A1
(en)
|
2005-04-28 |
2009-02-12 |
Mochida Pharmaceutical Co., Ltd. |
Anti-platelet membrane glycoprotein vi monoclonal antibody
|
|
KR101318469B1
(ko)
|
2005-05-09 |
2013-10-23 |
메다렉스, 인코포레이티드 |
예정 사멸 인자 1(ｐｄ-1)에 대한 인간 모노클로날 항체,및 항-ｐｄ-1 항체를 단독 사용하거나 기타 면역 요법제와병용한 암 치료 방법
|
|
KR101804078B1
(ko)
|
2005-06-08 |
2017-12-01 |
다나-파버 캔서 인스티튜트 인크. |
예정 세포사 1(ｐｄ-1) 경로를 억제함으로써 지속 감염 및 암을 치료하기 위한 방법 및 조성물
|
|
WO2007008463A2
(en)
*
|
2005-07-07 |
2007-01-18 |
Coley Pharmaceutical Group, Inc. |
Anti-ctla-4 antibody and cpg-motif-containing synthetic oligodeoxynucleotide combination therapy for cancer treatment
|
|
CN100443503C
(zh)
*
|
2005-07-18 |
2008-12-17 |
四川大学华西医院 |
人源化ctla-4单链抗体与人穿孔素通道形成肽p34的重组免疫毒素
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
EP2500355A3
(en)
|
2005-08-19 |
2012-10-24 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
RU2515108C2
(ru)
|
2005-08-19 |
2014-05-10 |
Эббви Инк |
Иммуноглобулин с двойными вариабельными доменами и его применения
|
|
AP2723A
(en)
|
2005-09-07 |
2013-08-31 |
Amgen Fremont Inc |
Human monoclonal antibodies to activ in receptor-like Kinase-1
|
|
US7700567B2
(en)
|
2005-09-29 |
2010-04-20 |
Supergen, Inc. |
Oligonucleotide analogues incorporating 5-aza-cytosine therein
|
|
WO2007039256A2
(de)
|
2005-09-30 |
2007-04-12 |
Abbott Gmbh & Co. Kg |
Bindungsdomänen von proteinen der repulsive guidance molecule (rgm) proteinfamilie und funktionale fragmente davon sowie deren verwendung
|
|
CA2626859A1
(en)
|
2005-11-08 |
2007-05-18 |
Medarex, Inc. |
Tnf-alpha blocker treatment for enterocolitis associated with immunostimulatory therapeutic antibody therapy
|
|
PL2289909T3
(pl)
|
2005-11-30 |
2015-04-30 |
Abbvie Inc |
Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał
|
|
CN102898519B
(zh)
|
2005-11-30 |
2015-10-28 |
Abbvie公司 |
抗淀粉样β蛋白的单克隆抗体及其用途
|
|
EP1954311A4
(en)
|
2005-12-07 |
2009-12-23 |
Medarex Inc |
CTLA-4 ANTIBODY DOSAGE ESCALATION THERAPY
|
|
US8216996B2
(en)
|
2006-03-03 |
2012-07-10 |
Ono Pharmaceutical Co., Ltd. |
Multimer of extracellular domain of cell surface functional molecule
|
|
WO2007123737A2
(en)
|
2006-03-30 |
2007-11-01 |
University Of California |
Methods and compositions for localized secretion of anti-ctla-4 antibodies
|
|
US7919079B2
(en)
*
|
2006-03-31 |
2011-04-05 |
Biosante Pharmaceuticals, Inc. |
Cancer immunotherapy compositions and methods of use
|
|
US8071323B2
(en)
|
2006-04-07 |
2011-12-06 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Human monoclonal antibodies that bind human insulin like growth factors and their use
|
|
MX2009001291A
(es)
|
2006-08-04 |
2009-03-10 |
Astrazeneca Ab |
Anticuerpos para erbb2.
|
|
NZ599144A
(en)
|
2006-09-08 |
2013-10-25 |
Abbott Lab |
Interleukin -13 binding proteins
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
EP2124952A2
(en)
|
2007-02-27 |
2009-12-02 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
US20090081237A1
(en)
|
2007-03-12 |
2009-03-26 |
Dana-Farber Cancer Institute |
Prognostic, diagnostic, and cancer therapeutic uses of FANCI and FANCI modulating agents
|
|
CN101808661A
(zh)
|
2007-04-02 |
2010-08-18 |
安进弗里蒙特公司 |
抗IgE抗体
|
|
ES2591281T3
(es)
|
2007-07-12 |
2016-11-25 |
Gitr, Inc. |
Terapias de combinación que emplean moléculas de enlazamiento a GITR
|
|
RU2499599C2
(ru)
|
2007-09-28 |
2013-11-27 |
Интрексон Корпорейшн |
Конструкции терапевтического переключения генов и биореакторы для экспрессии биотерапевтических молекул и их применение
|
|
EP2222697B1
(en)
|
2007-11-01 |
2012-12-05 |
Perseid Therapeutics LLC |
Immunosuppressive polypeptides and nucleic acids
|
|
SG186656A1
(en)
|
2007-12-14 |
2013-01-30 |
Bristol Myers Squibb Co |
Binding molecules to the human ox40 receptor
|
|
AU2009204194A1
(en)
|
2008-01-08 |
2009-07-16 |
Bristol-Myers Squibb Company |
Combination of anti-CTLA4 antibody with tubulin modulating agents for the treatment of proliferative diseases
|
|
WO2009100140A1
(en)
*
|
2008-02-04 |
2009-08-13 |
Medarex, Inc. |
Anti-clta-4 antibodies with reduced blocking of binding of ctla-4 to b7 and uses thereof
|
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
WO2009134776A2
(en)
|
2008-04-29 |
2009-11-05 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
|
NZ588713A
(en)
|
2008-05-09 |
2012-10-26 |
Abbott Gmbh & Co Kg |
Antibodies to receptor of advanced glycation end products (rage) and uses thereof
|
|
AR072001A1
(es)
|
2008-06-03 |
2010-07-28 |
Abbott Lab |
Inmunoglobulina con dominio variable dual y usos de la misma
|
|
KR20110016959A
(ko)
|
2008-06-03 |
2011-02-18 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
WO2010006059A1
(en)
|
2008-07-08 |
2010-01-14 |
Abbott Laboratories |
Prostaglandin e2 binding proteins and uses thereof
|
|
US8822645B2
(en)
|
2008-07-08 |
2014-09-02 |
Abbvie Inc. |
Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
|
|
WO2010014784A2
(en)
|
2008-08-01 |
2010-02-04 |
Bristol-Myers Squibb Company |
Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
NZ591471A
(en)
|
2008-08-18 |
2012-08-31 |
Pfizer |
Antibodies to ccr2
|
|
KR101012267B1
(ko)
*
|
2008-08-29 |
2011-02-08 |
주식회사 세이프로드 |
파손이 방지되는 차선규제봉 및 차선규제봉 시공방법
|
|
US8475790B2
(en)
|
2008-10-06 |
2013-07-02 |
Bristol-Myers Squibb Company |
Combination of CD137 antibody and CTLA-4 antibody for the treatment of proliferative diseases
|
|
US8685898B2
(en)
|
2009-01-15 |
2014-04-01 |
Imdaptive, Inc. |
Adaptive immunity profiling and methods for generation of monoclonal antibodies
|
|
CN102781470B
(zh)
|
2009-03-05 |
2016-01-20 |
Abbvie公司 |
Il-17结合蛋白
|
|
US8283162B2
(en)
|
2009-03-10 |
2012-10-09 |
Abbott Laboratories |
Antibodies relating to PIVKAII and uses thereof
|
|
KR101733255B1
(ko)
|
2009-07-20 |
2017-05-08 |
브리스톨-마이어스 스큅 컴퍼니 |
증식성 질환의 상승작용적 치료를 위한 항ｃｔｌａ４ 항체와 다양한 치료 요법의 조합
|
|
MY159837A
(en)
|
2009-08-29 |
2017-02-15 |
Abbvie Inc |
Therapeutic dll4 binding proteins
|
|
CA2772628A1
(en)
|
2009-09-01 |
2011-03-10 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
|
US8435516B2
(en)
|
2009-10-12 |
2013-05-07 |
Pfizer Inc. |
Cancer treatment
|
|
WO2011047262A2
(en)
|
2009-10-15 |
2011-04-21 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
US8420083B2
(en)
|
2009-10-31 |
2013-04-16 |
Abbvie Inc. |
Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
|
|
EP2510001B1
(en)
|
2009-12-08 |
2015-12-02 |
AbbVie Deutschland GmbH & Co KG |
Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
|
|
EP2542582A4
(en)
|
2010-03-02 |
2013-12-04 |
Abbvie Inc |
THERAPEUTIC PROTEINS LINKING TO DLL4
|
|
CN104744591B
(zh)
|
2010-04-15 |
2022-09-27 |
Abbvie德国有限责任两合公司 |
β淀粉样蛋白结合蛋白
|
|
MX2012013187A
(es)
|
2010-05-14 |
2013-03-22 |
Abbvie Inc |
Proteinas de union de il-1.
|
|
EP2571577A1
(en)
|
2010-05-17 |
2013-03-27 |
Bristol-Myers Squibb Company |
Improved immunotherapeutic dosing regimens and combinations thereof
|
|
US20120009196A1
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
US9120862B2
(en)
|
2010-07-26 |
2015-09-01 |
Abbott Laboratories |
Antibodies relating to PIVKA-II and uses thereof
|
|
KR20130100118A
(ko)
|
2010-08-03 |
2013-09-09 |
아비에 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
CA2808187A1
(en)
|
2010-08-14 |
2012-02-23 |
Abbvie Inc. |
Amyloid-beta binding proteins
|
|
HUE058226T2
(hu)
|
2010-08-19 |
2022-07-28 |
Zoetis Belgium S A |
NGF elleni antitestek és alkalmazásuk
|
|
PE20140229A1
(es)
|
2010-08-26 |
2014-03-27 |
Abbvie Inc |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
WO2012072806A1
(en)
*
|
2010-12-02 |
2012-06-07 |
Pieris Ag |
Muteins of human lipocalin 2 with affinity for ctla-4
|
|
MX348152B
(es)
|
2010-12-14 |
2017-06-02 |
Nat Univ Singapore |
Anticuerpo monoclonal humano con especificidad para el virus del dengue serotipo 1 proteina e y sus usos.
|
|
US20120275996A1
(en)
|
2010-12-21 |
2012-11-01 |
Abbott Laboratories |
IL-1 Binding Proteins
|
|
MX2013007332A
(es)
|
2010-12-21 |
2014-01-23 |
Abbvie Inc |
Inmunoglobulinas de dominio variable doble biespecificas de il-1 alfa y beta y su uso.
|
|
GB201103955D0
(en)
|
2011-03-09 |
2011-04-20 |
Antitope Ltd |
Antibodies
|
|
WO2012142164A1
(en)
|
2011-04-12 |
2012-10-18 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
|
|
RU2719132C2
(ru)
|
2011-06-30 |
2020-04-17 |
Чугаи Сейяку Кабусики Кайся |
Гетеродимеризованный полипептид
|
|
AU2012283039A1
(en)
|
2011-07-13 |
2014-01-30 |
Abbvie Inc. |
Methods and compositions for treating asthma using anti-IL-13 antibodies
|
|
WO2013013029A1
(en)
|
2011-07-19 |
2013-01-24 |
The Board Of Trustees Of The University Of Illinois |
Anti-clta4, anti-glut2 protein for the treatment of type 1 diabetes
|
|
CA2845585C
(en)
|
2011-08-30 |
2020-02-18 |
Astex Pharmaceuticals, Inc. |
Decitabine derivative formulations
|
|
CA2853258A1
(en)
|
2011-10-24 |
2013-05-02 |
Abbvie Inc. |
Immunobinders directed against sclerostin
|
|
UY34409A
(es)
|
2011-10-24 |
2013-05-31 |
Abbvie Inc |
Inmunoenlazadores dirigidos contra el tnf
|
|
IN2014CN04183A
(GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
|
2011-11-08 |
2015-07-17 |
Pfizer |
|
|
CA3204283A1
(en)
|
2011-12-14 |
2013-06-20 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
|
JP6336397B2
(ja)
|
2011-12-14 |
2018-06-06 |
アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー |
鉄関連障害を診断および治療するための組成物および方法
|
|
EP2797955A2
(en)
|
2011-12-30 |
2014-11-05 |
AbbVie Inc. |
Dual variable domain immunoglobulins against il-13 and/or il-17
|
|
PE20190907A1
(es)
|
2012-01-27 |
2019-06-26 |
AbbVie Deutschland GmbH and Co KG |
Composicion y metodo para el diagnostico y el tratamiento de las enfermedades asociadas a la degeneracion de las neuritas
|
|
WO2013138702A2
(en)
|
2012-03-15 |
2013-09-19 |
Bristol-Myers Squibb Company |
Methods for predicting gastrointestinal immune-related adverse events (gi-irae) in patients treated with modulation of the co-stimulatory pathway
|
|
US20150079100A1
(en)
|
2012-03-23 |
2015-03-19 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla-4 antibodies
|
|
WO2013155447A1
(en)
|
2012-04-13 |
2013-10-17 |
Children's Medical Center Corporation |
Tiki inhibitors
|
|
RU2737765C2
(ru)
|
2012-05-04 |
2020-12-02 |
Пфайзер Инк. |
Простатоассоциированные антигены и иммунотерапевтические схемы на основе вакцин
|
|
WO2013169971A1
(en)
|
2012-05-10 |
2013-11-14 |
Bristol-Myers Squibb Company |
Anti-tumor antibodies as predictive or prognostic biomarkers of efficacy and survival in ipilimumab-treated patients
|
|
IL289750B1
(en)
|
2012-05-15 |
2025-06-01 |
Bristol Myers Squibb Co |
Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
|
|
WO2013184871A1
(en)
|
2012-06-06 |
2013-12-12 |
Zoetis Llc |
Caninized anti-ngf antibodies and methods thereof
|
|
AR091649A1
(es)
|
2012-07-02 |
2015-02-18 |
Bristol Myers Squibb Co |
Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
|
|
TW201402608A
(zh)
|
2012-07-12 |
2014-01-16 |
Abbvie Inc |
Ｉｌ－１結合蛋白質
|
|
PT2887959T
(pt)
*
|
2012-08-23 |
2019-02-01 |
Seattle Genetics Inc |
Conjugados anticorpo-fármaco (adc) que se ligam a proteínas 158p1d7
|
|
MY194330A
(en)
|
2012-11-01 |
2022-11-28 |
Abbvie Inc |
Anti-dll4/vegf dual variable domain immunoglobulin and uses thereof
|
|
WO2014100542A1
(en)
|
2012-12-21 |
2014-06-26 |
Abbvie, Inc. |
High-throughput antibody humanization
|
|
HUE044430T2
(hu)
|
2013-03-01 |
2019-10-28 |
Astex Pharmaceuticals Inc |
Gyógyszerkombinációk
|
|
BR112015023212A2
(pt)
|
2013-03-14 |
2017-11-21 |
Gill Parkash |
tratamento do câncer utilizando anticorpos que se ligam à grp78 da superfície celular
|
|
CA2906421C
(en)
|
2013-03-14 |
2022-08-16 |
George J. Dawson |
Hcv antigen-antibody combination assay and methods and compositions for use therein
|
|
BR112015023355A8
(pt)
|
2013-03-14 |
2018-01-30 |
Abbott Lab |
antígenos recombinantes ns3 de hcv e mutantes dos mesmos para detecção de anticorpos aprimorada.
|
|
CA2906417C
(en)
|
2013-03-14 |
2022-06-21 |
Robert Ziemann |
Hcv core lipid binding domain monoclonal antibodies
|
|
BR112015023797A2
(pt)
|
2013-03-15 |
2017-10-24 |
Abbvie Inc |
proteínas de ligação de especificidade dupla dirigidas contra il-1b e/ou il-17
|
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
|
EP3632467B1
(en)
|
2013-06-07 |
2023-09-27 |
Duke University |
Inhibitors of complement factor h
|
|
BR112016002614B8
(pt)
|
2013-08-08 |
2023-11-07 |
Hopitaux Paris Assist Publique |
Imunocitoquina e composição farmacêutica
|
|
EP3030262B1
(en)
|
2013-08-08 |
2019-10-09 |
Cytune Pharma |
Combined pharmaceutical composition
|
|
LT3178849T
(lt)
|
2013-09-20 |
2019-06-10 |
Bristol-Myers Squibb Company |
Anti-lag-3 antikūnų ir anti-pd-1 antikūnų derinys, skirtas navikų gydymui
|
|
EP3062815B1
(en)
|
2013-11-01 |
2019-01-16 |
Pfizer Inc |
Vectors for expression of prostate-associated antigens
|
|
EP4461372A3
(en)
|
2013-11-05 |
2025-01-22 |
Cognate Bioservices, Inc. |
Combinations of checkpoint inhibitors and therapeutics to treat cancer
|
|
EP3066127A1
(en)
|
2013-11-06 |
2016-09-14 |
Bristol-Myers Squibb Company |
Immunotherapeutic dosing regimens and combinations thereof
|
|
EP3094650A2
(en)
|
2014-01-13 |
2016-11-23 |
Pieris Pharmaceuticals GmbH |
Multi-specific polypeptide useful for localized tumor immunomodulation
|
|
DK3148579T3
(da)
|
2014-05-28 |
2021-03-08 |
Agenus Inc |
Anti-gitr antistoffer og fremgangsmåder til anvendelse deraf
|
|
SI3151921T1
(sl)
|
2014-06-06 |
2019-12-31 |
Bristol-Myers Squibb Company |
Protitelesa proti z glukortikoidom induciranim receptorjem za faktor nekroze tumorja(GITR) in njihova uporaba
|
|
CN105296433B
(zh)
*
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
|
DK3186281T3
(da)
|
2014-08-28 |
2019-06-11 |
Halozyme Inc |
Kombinationsterapi med et hyaluronan-nedbrydende enzym og en immun-checkpoint-inhibitor
|
|
EP3110447B1
(en)
|
2014-09-16 |
2020-04-29 |
Synermore Biologics Co., Ltd. |
Anti-egfr antibody and uses of same
|
|
CN115040532A
(zh)
|
2014-10-10 |
2022-09-13 |
伊黛拉制药有限公司 |
使用tlr9激动剂与检查点抑制剂对癌症的治疗
|
|
CN108064282A
(zh)
|
2014-10-14 |
2018-05-22 |
哈洛齐梅公司 |
腺苷脱氨酶-2(ada2)、其变体的组合物及使用其的方法
|
|
WO2016070769A1
(zh)
*
|
2014-11-04 |
2016-05-12 |
北京韩美药品有限公司 |
同时阻断b7/cd28和il6/il6r/gp130信号通路的重组融合蛋白
|
|
CN105597090B
(zh)
*
|
2014-11-14 |
2022-08-23 |
中国科学院上海营养与健康研究所 |
一种提高cd4阳性t淋巴细胞存活率和活性的试剂及其应用
|
|
HUE052526T2
(hu)
|
2014-11-21 |
2021-05-28 |
Bristol Myers Squibb Co |
Antitestek, amelyek tartalmaznak módosított nehéz konstans régiókat
|
|
BR112017010110A2
(pt)
|
2014-11-21 |
2018-01-30 |
Bristol-Myers Squibb Company |
anticorpos contra cd73 e usos do mesmo
|
|
EA201791049A1
(ru)
|
2014-12-04 |
2017-10-31 |
Бристол-Майерс Сквибб Компани |
Комбинация анти-cs1 и анти-pd1 антител для лечения рака (миеломы)
|
|
CN104387453A
(zh)
*
|
2014-12-08 |
2015-03-04 |
深圳市同康生物医药有限公司 |
树突状细胞靶向肽及编码基因及应用
|
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
|
SG10202006538TA
(en)
|
2014-12-23 |
2020-08-28 |
Bristol Myers Squibb Co |
Antibodies to tigit
|
|
EP3240801B1
(en)
|
2014-12-31 |
2021-01-20 |
Checkmate Pharmaceuticals, Inc. |
Combination tumor immunotherapy
|
|
US10983128B2
(en)
|
2015-02-05 |
2021-04-20 |
Bristol-Myers Squibb Company |
CXCL11 and SMICA as predictive biomarkers for efficacy of anti-CTLA4 immunotherapy
|
|
CN114014930A
(zh)
*
|
2015-02-13 |
2022-02-08 |
索伦托药业有限公司 |
结合ctla4的抗体治疗剂
|
|
US20180133327A1
(en)
|
2015-03-16 |
2018-05-17 |
Amal Therapeutics Sa |
Cell Penetrating Peptides and Complexes Comprising the Same
|
|
US10376535B2
(en)
|
2015-03-26 |
2019-08-13 |
University Of Rochester |
Therapy for malignant disease
|
|
EP3797794A1
(en)
|
2015-04-07 |
2021-03-31 |
Cytlimic Inc. |
Medicine comprising a toll like receptor 3 agonist and a lag-3 protein
|
|
IL293646B2
(en)
|
2015-05-06 |
2024-07-01 |
Snipr Tech Ltd |
Changing bacterial populations and microbiota adaptation
|
|
JP7028765B2
(ja)
|
2015-05-22 |
2022-03-02 |
トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー |
ベンズアミドおよび活性化合物組成物および使用方法
|
|
HRP20230060T1
(hr)
|
2015-05-29 |
2023-03-17 |
Bristol-Myers Squibb Company |
Antitijela protiv ox40 i njihova primjena
|
|
JP6518917B2
(ja)
|
2015-05-29 |
2019-05-29 |
アッヴィ・インコーポレイテッド |
抗ｃｄ４０抗体およびその使用
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
|
|
EP3313528B1
(en)
|
2015-06-29 |
2021-08-04 |
Bristol-Myers Squibb Company |
Immunotherapeutic dosing regimens comprising pomalidomide and an anti-cs1 antibody for treating cancer
|
|
CN107922500A
(zh)
|
2015-06-29 |
2018-04-17 |
洛克菲勒大学 |
具有增强的激动剂活性的抗cd40抗体
|
|
CN108024535A
(zh)
|
2015-07-02 |
2018-05-11 |
大塚制药株式会社 |
冻干药物组合物
|
|
CN116059219A
(zh)
|
2015-07-16 |
2023-05-05 |
比奥克斯塞尔医疗股份有限公司 |
一种使用免疫调节治疗癌症的新颖方法
|
|
WO2017009843A2
(en)
|
2015-07-16 |
2017-01-19 |
Biokine Therapeutics Ltd. |
Compositions, articles of manufacture and methods for treating cancer
|
|
WO2017021913A1
(en)
|
2015-08-04 |
2017-02-09 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
|
EP3331919A1
(en)
|
2015-08-07 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
|
CA2998132A1
(en)
|
2015-09-11 |
2017-03-16 |
Nascent Biotech, Inc. |
Enhanced delivery of drugs to the brain
|
|
SI3370733T1
(sl)
|
2015-11-02 |
2021-11-30 |
Board Of Regents The University Of Texas System |
Postopek za aktivacijo CD40 in blokada imunske nadzorne točke
|
|
CN108350077A
(zh)
|
2015-11-03 |
2018-07-31 |
糖模拟物有限公司 |
产生单克隆抗体、造血干细胞的方法和组合物以及利用所述抗体和造血干细胞的方法
|
|
KR20180104597A
(ko)
|
2015-11-07 |
2018-09-21 |
멀티비르 인코포레이티드 |
암 치료를 위한 종양 억제 유전자 요법 및 면역관문 봉쇄를 포함하는 조성물
|
|
JP6983776B2
(ja)
|
2015-11-19 |
2021-12-17 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
グルココルチコイド誘発腫瘍壊死因子受容体（ｇｉｔｒ）に対する抗体およびその使用
|
|
TW202134282A
(zh)
|
2015-12-02 |
2021-09-16 |
美商艾吉納斯公司 |
抗體和使用彼之方法
|
|
MX2018007089A
(es)
|
2015-12-14 |
2019-01-30 |
Macrogenics Inc |
Moleculas biespecificas que tienen inmunorreactividad con pd-1 y ctla-4, y metodos de uso de las mismas.
|
|
EP3400023A1
(en)
|
2016-01-10 |
2018-11-14 |
ModernaTX, Inc. |
Therapeutic mrnas encoding anti ctla-4 antibodies
|
|
KR20180118725A
(ko)
|
2016-03-04 |
2018-10-31 |
브리스톨-마이어스 스큅 컴퍼니 |
항-cd73 항체와의 조합 요법
|
|
WO2017160599A1
(en)
|
2016-03-14 |
2017-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Use of cd300b antagonists to treat sepsis and septic shock
|
|
MX2018011204A
(es)
|
2016-03-15 |
2019-03-07 |
Mersana Therapeutics Inc |
Conjugados de anticuerpo-farmaco dirigidos a napi2b y sus metodos de uso.
|
|
LT3429618T
(lt)
|
2016-03-16 |
2024-05-10 |
Amal Therapeutics Sa |
Imuninės sistemos patikros taško moduliatoriaus ir komplekso, apimančio į ląsteles prasiskverbiantį peptidą, krovinį ir tlr peptido agonistą, derinys, skirtas naudoti medicinoje
|
|
US11046782B2
(en)
|
2016-03-30 |
2021-06-29 |
Musc Foundation For Research Development |
Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination
|
|
WO2017173334A1
(en)
|
2016-04-01 |
2017-10-05 |
Checkmate Pharmaceuticals, Inc. |
Fc receptor-mediated drug delivery
|
|
BR112018071307A2
(pt)
|
2016-04-18 |
2019-02-26 |
Celldex Therapeutics, Inc. |
anticorpos agonistas que ligam cd40 humana e usos dos mesmos
|
|
WO2017189976A1
(en)
|
2016-04-29 |
2017-11-02 |
Board Of Regents, The University Of Texas System |
Targeted measure of transcriptional activity related to hormone receptors
|
|
WO2017192874A1
(en)
|
2016-05-04 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Albumin-binding immunomodulatory compositions and methods of use thereof
|
|
AU2017268399B2
(en)
|
2016-05-18 |
2023-01-12 |
Modernatx, Inc. |
mRNA combination therapy for the treatment of cancer
|
|
US11052148B2
(en)
|
2016-05-30 |
2021-07-06 |
Geo Vax, Inc. |
Compositions and methods for generating an immune response to hepatitis B virus
|
|
US10994033B2
(en)
|
2016-06-01 |
2021-05-04 |
Bristol-Myers Squibb Company |
Imaging methods using 18F-radiolabeled biologics
|
|
GB201609811D0
(en)
|
2016-06-05 |
2016-07-20 |
Snipr Technologies Ltd |
Methods, cells, systems, arrays, RNA and kits
|
|
KR102531889B1
(ko)
|
2016-06-20 |
2023-05-17 |
키맵 리미티드 |
항-pd-l1 및 il-2 사이토카인
|
|
SG11201811600PA
(en)
|
2016-06-30 |
2019-01-30 |
Oncorus Inc |
Pseudotyped oncolytic viral delivery of therapeutic polypeptides
|
|
SG10201911972QA
(en)
|
2016-07-14 |
2020-02-27 |
Bristol Myers Squibb Co |
Antibodies against tim3 and uses thereof
|
|
NL2017270B1
(en)
*
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
|
WO2018025221A1
(en)
|
2016-08-04 |
2018-02-08 |
Glaxosmithkline Intellectual Property Development Limited |
Anti-icos and anti-pd-1 antibody combination therapy
|
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
|
IL265479B
(en)
|
2016-09-21 |
2022-09-01 |
Amal Therapeutics Sa |
Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer
|
|
JP7542946B2
(ja)
|
2016-09-27 |
2024-09-02 |
ボード オブ リージェンツ， ザ ユニヴァーシティー オブ テキサス システム |
マイクロバイオームをモジュレートすることにより、免疫チェックポイント遮断療法を増強するための方法
|
|
JP2019530875A
(ja)
|
2016-10-03 |
2019-10-24 |
アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ |
患者サンプルにおけるｕｃｈ−ｌ１状況を評価する改善された方法
|
|
US10618962B2
(en)
*
|
2016-10-10 |
2020-04-14 |
Crown Bioscience (Taicang) Inc. |
Anti-CTLA4 antibodies
|
|
WO2018070069A1
(ja)
|
2016-10-11 |
2018-04-19 |
サイトリミック株式会社 |
医薬
|
|
KR102661905B1
(ko)
|
2016-10-12 |
2024-04-29 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
Tusc2 면역요법을 위한 방법 및 조성물
|
|
JP7258747B2
(ja)
|
2016-10-28 |
2023-04-17 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗ｐｄ－１抗体を用いた尿路上皮癌の処置方法
|
|
CN118480125A
(zh)
|
2016-11-08 |
2024-08-13 |
齐鲁皮吉特湾生物治疗有限公司 |
抗pd1和抗ctla4抗体
|
|
US11883430B2
(en)
|
2016-11-09 |
2024-01-30 |
Musc Foundation For Research Development |
CD38-NAD+ regulated metabolic axis in anti-tumor immunotherapy
|
|
MA46770A
(fr)
|
2016-11-09 |
2019-09-18 |
Agenus Inc |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
|
US11446302B2
(en)
|
2016-11-17 |
2022-09-20 |
Board Of Regents, The University Of Texas System |
Compounds with anti-tumor activity against cancer cells bearing EGFR or HER2 exon 20 mutations
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
JP7080234B2
(ja)
|
2016-11-23 |
2022-06-03 |
トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー |
ベンズアミドおよび活性化合物組成物および使用方法
|
|
BR112019010878A2
(pt)
|
2016-11-29 |
2019-10-01 |
Lindhofer Horst |
combinação de anticorpos multifuncionais de redirecionamento de células t com moduladores de ponto de verificação imunológico e usos dos mesmos
|
|
JP2020500878A
(ja)
|
2016-12-01 |
2020-01-16 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ |
併用療法
|
|
KR20190090823A
(ko)
|
2016-12-01 |
2019-08-02 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
조합 요법
|
|
BR112019011794A2
(pt)
|
2016-12-12 |
2019-10-29 |
Daiichi Sankyo Co Ltd |
composição farmacêutica, e, método terapêutico.
|
|
US20200009203A1
(en)
|
2016-12-12 |
2020-01-09 |
Multivir Inc. |
Methods and compositions comprising viral gene therapy and an immune checkpoint inhibitor for treatment and prevention of cancer and infectious diseases
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
EP3585430A4
(en)
*
|
2017-02-21 |
2020-12-09 |
REMD Biotherapeutics, Inc. |
TREATMENT OF CANCER WITH ANTIBODIES THAT BIND TO T-CYTOTOXIC T-LYMPHOCYTES ANTIGEN-4 (CTLA-4)
|
|
EP3586136B1
(en)
|
2017-02-24 |
2023-11-08 |
Board Of Regents, The University Of Texas System |
Assay for detection of early stage pancreatic cancer
|
|
TW201834697A
(zh)
|
2017-02-28 |
2018-10-01 |
美商梅爾莎納醫療公司 |
Her2標靶抗體－藥物結合物之組合療法
|
|
EP3366703B1
(en)
|
2017-02-28 |
2019-04-03 |
Ralf Kleef |
Immune checkpoint therapy with hyperthermia
|
|
EP3596469A1
(en)
|
2017-03-12 |
2020-01-22 |
Yeda Research and Development Co., Ltd. |
Methods of diagnosing and prognosing cancer
|
|
WO2018167780A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of prognosing and treating cancer
|
|
CA3052513A1
(en)
|
2017-03-23 |
2018-09-27 |
Abbott Laboratories |
Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1
|
|
BR112019019795A2
(pt)
|
2017-03-31 |
2020-04-22 |
Bristol-Myers Squibb Company |
métodos para tratar tumor
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
JP7344797B2
(ja)
|
2017-04-15 |
2023-09-14 |
アボット・ラボラトリーズ |
早期バイオマーカーを使用する、ヒト対象における外傷性脳損傷の、超急性の診断及び決定の一助となるための方法
|
|
US11760777B2
(en)
|
2017-04-26 |
2023-09-19 |
Bristol-Myers Squibb Company |
Methods of antibody production that minimize disulfide bond reduction
|
|
CA3053410A1
(en)
|
2017-04-28 |
2018-11-01 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
|
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
|
CN108948194B
(zh)
*
|
2017-05-19 |
2023-02-17 |
上海药明生物技术有限公司 |
一种新的ctla-4单克隆抗体
|
|
EA201992755A1
(ru)
*
|
2017-05-19 |
2020-04-22 |
Уси Байолоджикс (Шанхай) Ко. Лтд. |
Новые моноклональные антитела к белку 4, ассоциированному с цитотоксическими т-лимфоцитами, (ctla-4)
|
|
AU2018272054B2
(en)
|
2017-05-25 |
2024-10-31 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
|
KR20220167342A
(ko)
|
2017-05-25 |
2022-12-20 |
브리스톨-마이어스 스큅 컴퍼니 |
변형된 중쇄 불변 영역을 포함하는 항체
|
|
CN110720041B
(zh)
|
2017-05-30 |
2024-04-26 |
雅培实验室 |
用心肌肌钙蛋白i和早期生物标记物帮助诊断和评价人受试者中轻度创伤性脑损伤的方法
|
|
PL3631454T3
(pl)
|
2017-05-30 |
2024-01-29 |
Bristol-Myers Squibb Company |
Leczenie guzów lag-3 pozytywnych
|
|
KR20200010500A
(ko)
|
2017-05-30 |
2020-01-30 |
브리스톨-마이어스 스큅 컴퍼니 |
항-lag-3 항체, pd-1 경로 억제제, 및 면역요법제의 조합을 포함하는 조성물
|
|
KR102721137B1
(ko)
|
2017-05-30 |
2024-10-25 |
브리스톨-마이어스 스큅 컴퍼니 |
항-lag-3 항체 또는 항-lag-3 항체 및 항-pd-1 또는 항-pd-l1 항체를 포함하는 조성물
|
|
WO2018226336A1
(en)
|
2017-06-09 |
2018-12-13 |
Providence Health & Services - Oregon |
Utilization of cd39 and cd103 for identification of human tumor reactive cells for treatment of cancer
|
|
EP3649474A1
(en)
|
2017-07-03 |
2020-05-13 |
Abbott Laboratories |
Improved methods for measuring ubiquitin carboxy-terminal hydrolase l1 levels in blood
|
|
BR112020000523A2
(pt)
|
2017-07-14 |
2020-07-14 |
Innate Tumor Immunity, Inc. |
moduladores de nlrp3
|
|
EA202090286A1
(ru)
|
2017-07-14 |
2020-05-12 |
Пфайзер, Инк. |
АНТИТЕЛА К MAdCAM
|
|
TWI799432B
(zh)
*
|
2017-07-27 |
2023-04-21 |
美商再生元醫藥公司 |
抗ctla-4抗體及其用途
|
|
EP3661522A2
(en)
|
2017-08-03 |
2020-06-10 |
Otsuka Pharmaceutical Co., Ltd. |
Drug compound and purification methods thereof
|
|
WO2019036855A1
(en)
|
2017-08-21 |
2019-02-28 |
Adagene Inc. |
Anti-cd137 molecules and use thereof
|
|
CA3078458A1
(en)
|
2017-10-06 |
2019-04-11 |
The Wistar Institute Of Anatomy And Biology |
Dna monoclonal antibodies targeting ctla-4 for the treatment and prevention of cancer
|
|
US11230601B2
(en)
|
2017-10-10 |
2022-01-25 |
Tilos Therapeutics, Inc. |
Methods of using anti-lap antibodies
|
|
CN111247169A
(zh)
|
2017-10-15 |
2020-06-05 |
百时美施贵宝公司 |
治疗肿瘤的方法
|
|
KR20200074214A
(ko)
|
2017-11-01 |
2020-06-24 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하는데 사용하기 위한 면역자극 효능작용 항체
|
|
EP3707165A4
(en)
|
2017-11-07 |
2021-09-08 |
The Board of Regents of The University of Texas System |
TARGETING LILRB4 WITH CAR-T OR CAR-NK CELLS IN CANCER TREATMENT
|
|
US11638760B2
(en)
|
2017-11-27 |
2023-05-02 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
CN108003238B
(zh)
*
|
2017-11-30 |
2021-02-02 |
常州费洛斯药业科技有限公司 |
一种能特异识别ctla-4的全人源单克隆抗体或抗体片段及其方法和用途
|
|
WO2019113525A2
(en)
|
2017-12-09 |
2019-06-13 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
|
|
CA3067055A1
(en)
|
2017-12-09 |
2019-06-13 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of gfap and uch-l1
|
|
KR102476887B1
(ko)
*
|
2017-12-20 |
2022-12-13 |
하버 바이오메드 (상하이) 컴퍼니 리미티드 |
Ctla-4에 결합하는 항체 및 이의 용도
|
|
CN111757757A
(zh)
|
2017-12-21 |
2020-10-09 |
梅尔莎纳医疗公司 |
吡咯并苯并二氮呯抗体共轭物
|
|
JP7284759B2
(ja)
|
2017-12-27 |
2023-05-31 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗ｃｄ４０抗体およびその使用
|
|
EP3731850A4
(en)
|
2017-12-29 |
2021-12-01 |
Oncorus, Inc. |
ONCOLYTIC VIRUS DELIVERY OF THERAPEUTIC POLYPEPTIDES
|
|
US12129297B2
(en)
|
2018-01-12 |
2024-10-29 |
Bristol-Myers Squibb Company |
Antibodies against TIM3 and uses thereof
|
|
US20190224205A1
(en)
|
2018-01-22 |
2019-07-25 |
Bristol-Myers Squibb Company |
Compositions and methods of treating cancer
|
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
|
US12246031B2
(en)
|
2018-02-13 |
2025-03-11 |
Checkmate Pharmaceuticals, Inc. |
Compositions and methods for tumor immunotherapy
|
|
JP2021517589A
(ja)
|
2018-03-12 |
2021-07-26 |
アンセルム（アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル） |
癌の治療のための化学免疫療法を増強するためのカロリー制限模倣物の使用
|
|
EP3765499A1
(en)
|
2018-03-12 |
2021-01-20 |
Zoetis Services LLC |
Anti-ngf antibodies and methods thereof
|
|
US20230167177A1
(en)
*
|
2018-03-19 |
2023-06-01 |
WuXi Biologics Ireland Limited |
Novel anti-ctla-4 antibody polypeptide
|
|
US20210094991A1
(en)
|
2018-03-19 |
2021-04-01 |
Multivir Inc. |
Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer
|
|
CN111971304A
(zh)
|
2018-03-21 |
2020-11-20 |
戊瑞治疗有限公司 |
在酸性pH结合至VISTA的抗体
|
|
EP3768715A1
(en)
|
2018-03-23 |
2021-01-27 |
Bristol-Myers Squibb Company |
Antibodies against mica and/or micb and uses thereof
|
|
SG11202009504YA
(en)
|
2018-03-25 |
2020-10-29 |
Snipr Biome Aps |
Treating & preventing microbial infections
|
|
US10760075B2
(en)
|
2018-04-30 |
2020-09-01 |
Snipr Biome Aps |
Treating and preventing microbial infections
|
|
CA3094108A1
(en)
|
2018-03-27 |
2019-10-03 |
Board Of Regents, The University Of Texas Systems |
Compounds with anti-tumor activity against cancer cells bearing her2 exon 19 mutations
|
|
JP2021519771A
(ja)
|
2018-03-30 |
2021-08-12 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
腫瘍を処置する方法
|
|
IL319506A
(en)
|
2018-04-09 |
2025-05-01 |
Checkmate Pharmaceuticals Inc |
Packaging of oligonucleotides in virus-like particles
|
|
AU2019256539A1
(en)
|
2018-04-18 |
2020-11-26 |
Xencor, Inc. |
PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof
|
|
WO2019204592A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Il-15/il-15ra heterodimeric fc fusion proteins and uses thereof
|
|
EP3784670B1
(en)
|
2018-04-25 |
2023-11-29 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
EP3810109B1
(en)
|
2018-05-31 |
2024-08-07 |
Peloton Therapeutics, Inc. |
Compounds and compositions for inhibiting cd73
|
|
CN112566643A
(zh)
|
2018-06-12 |
2021-03-26 |
加利福尼亚大学董事会 |
用于治疗癌症的单链双特异性嵌合抗原受体
|
|
TW202428604A
(zh)
|
2018-07-09 |
2024-07-16 |
美商戊瑞治療有限公司 |
結合至ilt4的抗體
|
|
CA3106143A1
(en)
|
2018-07-11 |
2020-01-16 |
Actym Therapeutics, Inc. |
Engineered immunostimulatory bacterial strains and uses thereof
|
|
JP7700036B2
(ja)
|
2018-07-11 |
2025-06-30 |
ファイヴ プライム セラピューティクス インク |
酸性ｐＨでＶＩＳＴＡと結合する抗体
|
|
EP3823673A4
(en)
|
2018-07-20 |
2022-05-11 |
Surface Oncology, Inc. |
Anti-cd112r compositions and methods
|
|
ES2974964T3
(es)
|
2018-08-16 |
2024-07-02 |
Innate Tumor Immunity Inc |
Moduladores de NLRP3 derivados de imidazo[4,5-c]quinolina
|
|
WO2020037091A1
(en)
|
2018-08-16 |
2020-02-20 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
JP2021534180A
(ja)
|
2018-08-16 |
2021-12-09 |
イネイト・テューマー・イミュニティ・インコーポレイテッドInnate Tumor Immunity, Inc. |
置換４−アミノ−１Ｈ−イミダゾ［４，５−ｃ］キノリン化合物およびその製造の改良法
|
|
EP3617230A1
(en)
|
2018-09-03 |
2020-03-04 |
BioInvent International AB |
Novel antibodies and nucleotide sequences, and uses thereof
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
WO2020058372A1
(en)
|
2018-09-19 |
2020-03-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of cancers resistant to immune checkpoint therapy
|
|
WO2020057645A1
(zh)
|
2018-09-21 |
2020-03-26 |
信达生物制药(苏州)有限公司 |
新型白介素2及其用途
|
|
US12269855B2
(en)
|
2018-09-21 |
2025-04-08 |
Innovent Biologics (Suzhou) Co., Ltd. |
Interleukin-2 and use thereof
|
|
WO2020070053A1
(en)
|
2018-10-01 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
MA53822A
(fr)
|
2018-10-03 |
2021-08-11 |
Xencor Inc |
Protéines de fusion fc hétérodimères d'il -12
|
|
US11130802B2
(en)
|
2018-10-10 |
2021-09-28 |
Tilos Therapeutics, Inc. |
Anti-lap antibody variants
|
|
CR20210239A
(es)
|
2018-10-12 |
2021-12-15 |
Xencor Inc |
Proteínas de fusión de il-15/il-15ralfa-fc dirigidas a pd-1 y usos de las mismas en terapias combinadas
|
|
EP3870609A1
(en)
|
2018-10-23 |
2021-09-01 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
AU2019369340A1
(en)
|
2018-10-29 |
2021-05-20 |
Mersana Therapeutics, Inc. |
Cysteine engineered antibody-drug conjugates with peptide-containing linkers
|
|
NZ777032A
(en)
|
2018-11-16 |
2024-07-26 |
Bristol Myers Squibb Co |
Anti-nkg2a antibodies and uses thereof
|
|
EP3883955A1
(en)
|
2018-11-19 |
2021-09-29 |
Board of Regents, The University of Texas System |
A modular, polycistronic vector for car and tcr transduction
|
|
BR112021010297A2
(pt)
|
2018-11-28 |
2021-08-24 |
Board Of Regents, The University Of Texas System |
Edição de genomas multiplexadores de células imunes para aumentar a funcionalidade e resistência ao ambiente supressivo
|
|
JP2022513653A
(ja)
|
2018-11-28 |
2022-02-09 |
ブリストル－マイヤーズ スクイブ カンパニー |
修飾された重鎖定常領域を含む抗体
|
|
ES2971964T3
(es)
|
2018-11-28 |
2024-06-10 |
Inst Nat Sante Rech Med |
Métodos y kit para someter a ensayo el potencial lítico de células efectoras inmunitarias
|
|
CN113316455A
(zh)
|
2018-11-29 |
2021-08-27 |
得克萨斯大学体系董事会 |
用于离体扩增自然杀伤细胞的方法及其用途
|
|
WO2020115262A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
CA3117710A1
(en)
|
2018-12-11 |
2020-06-18 |
Theravance Biopharma R&D Ip, Llc |
Alk5 inhibitors
|
|
EP3897624A1
(en)
|
2018-12-17 |
2021-10-27 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of sulconazole as a furin inhibitor
|
|
CN113490688B
(zh)
|
2018-12-26 |
2025-07-29 |
希望之城公司 |
可活化的被掩蔽的抗ctla4结合蛋白质
|
|
WO2020136235A1
(en)
|
2018-12-28 |
2020-07-02 |
Transgene Sa |
M2-defective poxvirus
|
|
US12338228B2
(en)
|
2019-01-14 |
2025-06-24 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
|
JP7373571B2
(ja)
|
2019-01-14 |
2023-11-02 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
がん治療に用いるためのｎｌｒｐ３モジュレーターとしての置換キナゾリン
|
|
EP3911641A1
(en)
|
2019-01-14 |
2021-11-24 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
JP7506079B2
(ja)
|
2019-01-14 |
2024-06-25 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
がんの治療に用いるためのヘテロ環ｎｌｒｐ３モジュレーター
|
|
US20220098264A1
(en)
|
2019-01-15 |
2022-03-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Mutated interleukin-34 (il-34) polypeptides and uses thereof in therapy
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
JP7650507B2
(ja)
|
2019-03-13 |
2025-03-25 |
イーザアールエヌーエー イムノセラピーズ エンヴェー |
ｍＲＮＡワクチン
|
|
JP2022527177A
(ja)
|
2019-03-28 |
2022-05-31 |
ブリストル－マイヤーズ スクイブ カンパニー |
腫瘍を処置する方法
|
|
WO2020198676A1
(en)
|
2019-03-28 |
2020-10-01 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3947640A4
(en)
|
2019-04-02 |
2022-12-14 |
The Brigham & Women's Hospital, Inc. |
METHODS OF IDENTIFYING THE PROGRESSION OF A PRIMARY MELANOMA
|
|
JP2022527972A
(ja)
|
2019-04-02 |
2022-06-07 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
前悪性病変を有する患者において癌を予測及び予防する方法
|
|
EP3952850A1
(en)
|
2019-04-09 |
2022-02-16 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
|
US20220220480A1
(en)
|
2019-04-17 |
2022-07-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
|
KR20220007879A
(ko)
|
2019-05-09 |
2022-01-19 |
후지필름 셀룰러 다이내믹스, 인코포레이티드 |
간세포 생성 방법
|
|
CA3139162A1
(en)
|
2019-05-17 |
2020-11-26 |
Cancer Prevention Pharmaceuticals, Inc. |
Methods for treating familial adenomatous polyposis
|
|
JP2022534967A
(ja)
|
2019-05-30 |
2022-08-04 |
ブリストル－マイヤーズ スクイブ カンパニー |
多腫瘍遺伝子シグネチャーおよびその使用
|
|
JP2022534981A
(ja)
|
2019-05-30 |
2022-08-04 |
ブリストル－マイヤーズ スクイブ カンパニー |
細胞局在化シグネチャーおよび組み合わせ治療
|
|
KR20220016155A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
면역-종양학 (i-o) 요법에 적합한 대상체를 확인하는 방법
|
|
EP3976111A4
(en)
|
2019-06-03 |
2023-07-05 |
The University of Chicago |
Methods and compositions for treating cancer with collagen binding drug carriers
|
|
MX2021014867A
(es)
|
2019-06-03 |
2022-03-25 |
Univ Chicago |
Metodos y composiciones para el tratamiento del cancer con adyuvantes dirigidos al cancer.
|
|
US20210038684A1
(en)
|
2019-06-11 |
2021-02-11 |
Alkermes Pharma Ireland Limited |
Compositions and Methods for Cancer Immunotherapy
|
|
BR112021025170A2
(pt)
|
2019-06-27 |
2022-01-25 |
Etherna Immunotherapies Nv |
Terapia de combinação
|
|
EP3994270A1
(en)
|
2019-07-02 |
2022-05-11 |
Fred Hutchinson Cancer Research Center |
Recombinant ad35 vectors and related gene therapy improvements
|
|
CN114174337B
(zh)
|
2019-07-15 |
2024-10-25 |
英特维特国际股份有限公司 |
针对犬ctla-4的犬源化抗体
|
|
BR112022000604A2
(pt)
|
2019-07-15 |
2022-03-03 |
Intervet Int Bv |
Anticorpos caninizados para ctla-4 humana
|
|
WO2021024742A1
(ja)
*
|
2019-08-06 |
2021-02-11 |
国立大学法人筑波大学 |
細胞傷害アッセイ方法
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
BR112022004791A2
(pt)
|
2019-09-17 |
2022-06-21 |
Bial R&D Invest S A |
Carboxamidas de imidazol substituídas e seu uso no tratamento de distúrbios médicos
|
|
EP4031535A1
(en)
|
2019-09-17 |
2022-07-27 |
Bial-R&D Investments, S.A. |
Substituted n-heterocyclic carboxamides as acid ceramidase inhibitors and their use as medicaments
|
|
CN114901652A
(zh)
|
2019-09-17 |
2022-08-12 |
比亚尔R&D投资股份公司 |
用于治疗医学病症的经取代的饱和和不饱和n-杂环甲酰胺及相关化合物
|
|
JP7650867B2
(ja)
|
2019-09-19 |
2025-03-25 |
ブリストル－マイヤーズ スクイブ カンパニー |
酸性ｐＨでＶＩＳＴＡと結合する抗体
|
|
CN114450028A
(zh)
|
2019-09-22 |
2022-05-06 |
百时美施贵宝公司 |
Lag-3拮抗剂治疗的定量空间剖析
|
|
CA3151747A1
(en)
|
2019-09-23 |
2021-04-01 |
James J. MOON |
Compositions and methods for increasing the efficacy of immunotherapies and vaccines
|
|
JP2022549854A
(ja)
|
2019-09-25 |
2022-11-29 |
サーフィス オンコロジー インコーポレイテッド |
抗ｉｌ－２７抗体及びその使用
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
WO2021067863A2
(en)
|
2019-10-03 |
2021-04-08 |
Xencor, Inc. |
Targeted il-12 heterodimeric fc-fusion proteins
|
|
US20220363776A1
(en)
|
2019-10-04 |
2022-11-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
US20240190961A1
(en)
|
2019-10-25 |
2024-06-13 |
Daiichi Sankyo Company, Limited |
Combination of anti-garp antibody and immunomodulator
|
|
US20220380765A1
(en)
|
2019-11-02 |
2022-12-01 |
Board Of Regents, The University Of Texas System |
Targeting nonsense-mediated decay to activate p53 pathway for the treatment of cancer
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
AU2020380384A1
(en)
|
2019-11-08 |
2022-05-26 |
Bristol-Myers Squibb Company |
LAG-3 antagonist therapy for melanoma
|
|
KR20220104208A
(ko)
|
2019-11-22 |
2022-07-26 |
세라밴스 바이오파마 알앤디 아이피, 엘엘씨 |
Alk5 억제제로서 치환된 1,5-나프티리딘 또는 퀴놀린
|
|
TW202128155A
(zh)
|
2019-11-27 |
2021-08-01 |
日商賽多利克公司 |
醫藥組成物
|
|
WO2021113644A1
(en)
|
2019-12-05 |
2021-06-10 |
Multivir Inc. |
Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer
|
|
IL294085A
(en)
|
2019-12-19 |
2022-08-01 |
Bristol Myers Squibb Co |
Combinations of dgk inhibitors and checkpoint antagonists
|
|
WO2021131021A1
(ja)
|
2019-12-27 |
2021-07-01 |
中外製薬株式会社 |
抗ｃｔｌａ－４抗体およびその使用
|
|
CA3161733A1
(en)
|
2020-01-07 |
2021-05-15 |
Everett Stone |
Improved human methylthioadenosine/adenosine depleting enzyme variants for cancer therapy
|
|
US20230348458A1
(en)
|
2020-01-10 |
2023-11-02 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
EP4100435A1
(en)
|
2020-02-05 |
2022-12-14 |
Larimar Therapeutics, Inc. |
Tat peptide binding proteins and uses thereof
|
|
JP2023514152A
(ja)
|
2020-02-06 |
2023-04-05 |
ブリストル－マイヤーズ スクイブ カンパニー |
Ｉｌ－１０およびその使用
|
|
EP4107173A1
(en)
|
2020-02-17 |
2022-12-28 |
Board of Regents, The University of Texas System |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
|
US20230045494A1
(en)
|
2020-02-28 |
2023-02-09 |
Orega Biotech |
Combination therapies based on ctla4 and il-17b inhibitors
|
|
WO2022074464A2
(en)
|
2020-03-05 |
2022-04-14 |
Neotx Therapeutics Ltd. |
Methods and compositions for treating cancer with immune cells
|
|
KR20220151189A
(ko)
|
2020-03-09 |
2022-11-14 |
브리스톨-마이어스 스큅 컴퍼니 |
증진된 효능제 활성을 갖는 cd40에 대한 항체
|
|
JP2023519346A
(ja)
|
2020-03-27 |
2023-05-10 |
メンドゥス・ベスローテン・フェンノートシャップ |
養子細胞療法の有効性を増強するための白血病由来の改変細胞のエクスビボ（ｅｘ ｖｉｖｏ）使用
|
|
JP2023519673A
(ja)
|
2020-03-31 |
2023-05-12 |
セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー |
置換ピリミジンおよび使用方法
|
|
WO2021207449A1
(en)
|
2020-04-09 |
2021-10-14 |
Merck Sharp & Dohme Corp. |
Affinity matured anti-lap antibodies and uses thereof
|
|
EP4136459A1
(en)
|
2020-04-13 |
2023-02-22 |
Abbott Laboratories |
Methods, complexes and kits for detecting or determining an amount of a ss-coronavirus antibody in a sample
|
|
JP2023522691A
(ja)
|
2020-04-21 |
2023-05-31 |
ユニバーシティ オブ ロチェスター |
ヒト精巣上体タンパク質４の阻害剤
|
|
AU2021258257A1
(en)
|
2020-04-22 |
2022-11-10 |
Iovance Biotherapeutics, Inc. |
Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy
|
|
BR112022022986A2
(pt)
|
2020-05-13 |
2023-01-17 |
Disc Medicine Inc |
Anticorpos anti-hemojuvelina (hjv) para tratar mielofibrose
|
|
WO2021228178A1
(en)
|
2020-05-13 |
2021-11-18 |
Adagene Ag |
Compositions and methods for treating cancer
|
|
US20230192867A1
(en)
|
2020-05-15 |
2023-06-22 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
CA3178726A1
(en)
|
2020-05-21 |
2021-11-25 |
Gregory LIZEE |
T cell receptors with vgll1 specificity and uses thereof
|
|
WO2021247908A1
(en)
|
2020-06-03 |
2021-12-09 |
Bionecure Therapeutics, Inc. |
Trophoblast cell-surface antigen-2 (trop-2) antibodies
|
|
WO2021247836A1
(en)
|
2020-06-03 |
2021-12-09 |
Board Of Regents, The University Of Texas System |
Methods for targeting shp-2 to overcome resistance
|
|
JP2023528071A
(ja)
|
2020-06-03 |
2023-07-03 |
エムヴィ バイオセラピューティクス エスエー |
Ａｔｐ加水分解酵素と免疫チェックポイントモジュレーターとの組合せ、並びにその使用
|
|
JP2023530275A
(ja)
|
2020-06-10 |
2023-07-14 |
セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー |
Ａｌｋ５阻害剤として有用なナフチリジン誘導体
|
|
US20230293530A1
(en)
|
2020-06-24 |
2023-09-21 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
|
CN116133679A
(zh)
|
2020-06-30 |
2023-05-16 |
门德斯有限公司 |
白血病衍生细胞在卵巢癌疫苗中的用途
|
|
WO2022003156A1
(en)
|
2020-07-02 |
2022-01-06 |
Oncurious Nv |
Ccr8 non-blocking binders
|
|
EP4178611A1
(en)
|
2020-07-07 |
2023-05-17 |
BioNTech SE |
Therapeutic rna for hpv-positive cancer
|
|
AU2021305084A1
(en)
|
2020-07-07 |
2023-02-02 |
Cancure, Llc |
MIC antibodies and binding agents and methods of using the same
|
|
JP2023534987A
(ja)
|
2020-07-24 |
2023-08-15 |
アムジエン・インコーポレーテツド |
Ｓａｒｓ－ｃｏｖ２スパイクタンパク質に由来する免疫原
|
|
US20230295146A1
(en)
|
2020-07-24 |
2023-09-21 |
The University Of Rochester |
Inhibitors of interleukin-1 receptor-associated kinases 1 and 4
|
|
EP4193149A1
(en)
|
2020-08-04 |
2023-06-14 |
Abbott Laboratories |
Improved methods and kits for detecting sars-cov-2 protein in a sample
|
|
CN112359052B
(zh)
*
|
2020-08-20 |
2023-01-03 |
山东兴瑞生物科技有限公司 |
抗EpCAM嵌合抗原受体的编码基因、制备方法、具有该基因的质粒、免疫细胞及其应用
|
|
IL300813A
(en)
|
2020-08-28 |
2023-04-01 |
Bristol Myers Squibb Co |
LAG-3 antagonist therapy for hepatocellular carcinoma
|
|
EP4204453A1
(en)
|
2020-08-31 |
2023-07-05 |
Bristol-Myers Squibb Company |
Cell localization signature and immunotherapy
|
|
JP2023548051A
(ja)
|
2020-10-23 |
2023-11-15 |
ブリストル－マイヤーズ スクイブ カンパニー |
肺がんのためのｌａｇ－３アンタゴニスト療法
|
|
EP4240377A4
(en)
|
2020-11-05 |
2025-01-15 |
Board of Regents, The University of Texas System |
Engineered t cell receptors targeting egfr antigens and methods of use
|
|
IL302728A
(en)
|
2020-11-13 |
2023-07-01 |
Catamaran Bio Inc |
Genetically modified natural killer cells and methods of use thereof
|
|
AU2021388155A1
(en)
|
2020-11-25 |
2023-06-15 |
Catamaran Bio, Inc. |
Cellular therapeutics engineered with signal modulators and methods of use thereof
|
|
WO2022119841A1
(en)
|
2020-12-01 |
2022-06-09 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
PH12023500013A1
(en)
|
2020-12-04 |
2024-03-11 |
Tidal Therapeutics Inc |
Ionizable cationic lipids and lipi nanoparticles, and methods of synthesis and use thereof
|
|
US20240034786A1
(en)
*
|
2020-12-10 |
2024-02-01 |
WuXi Biologics Ireland Limited |
An antibody against p-cadherin and uses thereof
|
|
WO2022130206A1
(en)
|
2020-12-16 |
2022-06-23 |
Pfizer Inc. |
TGFβr1 INHIBITOR COMBINATION THERAPIES
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性ｒｎａ
|
|
EP4267618A1
(en)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Non-blocking human ccr8 binders
|
|
US20240076391A1
(en)
|
2020-12-24 |
2024-03-07 |
Oncurious Nv |
Human ccr8 binders
|
|
WO2022136650A1
(en)
|
2020-12-24 |
2022-06-30 |
Oncurious Nv |
Murine cross-reactive human ccr8 binders
|
|
WO2022146948A1
(en)
|
2020-12-28 |
2022-07-07 |
Bristol-Myers Squibb Company |
Subcutaneous administration of pd1/pd-l1 antibodies
|
|
EP4566674A3
(en)
|
2020-12-28 |
2025-08-06 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
WO2022147147A1
(en)
|
2020-12-30 |
2022-07-07 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
|
CA3205538A1
(en)
|
2021-01-19 |
2022-07-28 |
Han XIAO |
Bone-specific delivery of polypeptides
|
|
CN116723854A
(zh)
|
2021-01-22 |
2023-09-08 |
门德斯有限公司 |
肿瘤疫苗接种方法
|
|
KR20230150295A
(ko)
|
2021-01-29 |
2023-10-30 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
키나제 억제제를 이용한 암의 치료 방법
|
|
EP4304633A1
(en)
|
2021-03-12 |
2024-01-17 |
Mendus B.V. |
Methods of vaccination and use of cd47 blockade
|
|
WO2022212876A1
(en)
|
2021-04-02 |
2022-10-06 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
EP4070799A1
(en)
|
2021-04-08 |
2022-10-12 |
Nuvamid SA |
Compositions for the improvement of sport performance
|
|
EP4319820A1
(en)
|
2021-04-10 |
2024-02-14 |
Profoundbio Us Co. |
Folr1 binding agents, conjugates thereof and methods of using the same
|
|
EP4079310A1
(en)
|
2021-04-20 |
2022-10-26 |
Nuvamid SA |
Nmn and derivatives for its use in the treatment of alpha-synucleinopathies
|
|
EP4079311A1
(en)
|
2021-04-20 |
2022-10-26 |
Nuvamid SA |
Nmn and derivatives for its use in the treatment of depression and/or anxiety in patients having a form of parkinsonism
|
|
US20240424090A1
(en)
|
2021-04-20 |
2024-12-26 |
Institut Curie |
Compositions and methods for use in immunotherapy
|
|
WO2022226317A1
(en)
|
2021-04-23 |
2022-10-27 |
Profoundbio Us Co. |
Anti-cd70 antibodies, conjugates thereof and methods of using the same
|
|
WO2022245920A1
(en)
|
2021-05-18 |
2022-11-24 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
|
WO2022251359A1
(en)
|
2021-05-26 |
2022-12-01 |
Theravance Biopharma R&D Ip, Llc |
Bicyclic inhibitors of alk5 and methods of use
|
|
KR20240049794A
(ko)
|
2021-06-07 |
2024-04-17 |
프로비던스 헬스 앤드 서비시즈 - 오레곤 |
Cxcr5, pd-1, 및 icos 발현 종양 반응성 cd4 t 세포 및 그의 용도
|
|
US20240118279A1
(en)
|
2021-06-14 |
2024-04-11 |
Abbott Laboratories |
Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
|
|
WO2022270611A1
(ja)
|
2021-06-25 |
2022-12-29 |
中外製薬株式会社 |
抗ｃｔｌａ－４抗体
|
|
AR126236A1
(es)
|
2021-06-25 |
2023-10-04 |
Chugai Pharmaceutical Co Ltd |
Uso del anticuerpo anti-ctla-4
|
|
EP4367269A1
(en)
|
2021-07-05 |
2024-05-15 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
CA3225254A1
(en)
|
2021-07-13 |
2023-01-19 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
|
WO2023014922A1
(en)
|
2021-08-04 |
2023-02-09 |
The Regents Of The University Of Colorado, A Body Corporate |
Lat activating chimeric antigen receptor t cells and methods of use thereof
|
|
KR20240099138A
(ko)
|
2021-08-23 |
2024-06-28 |
이뮤니타스 테라퓨틱스, 인크. |
항-cd161 항체 및 그의 용도
|
|
JP2024534849A
(ja)
|
2021-08-31 |
2024-09-26 |
アボット・ラボラトリーズ |
脳の損傷を診断する方法及びシステム
|
|
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(zh)
|
2021-08-31 |
2024-09-27 |
雅培实验室 |
诊断脑损伤的方法和系统
|
|
WO2023056268A1
(en)
|
2021-09-30 |
2023-04-06 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
EP4413117A1
(en)
|
2021-10-05 |
2024-08-14 |
Cytovia Therapeutics, Llc. |
Natural killer cells and methods of use thereof
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
PE20242001A1
(es)
|
2021-10-20 |
2024-09-27 |
Takeda Pharmaceuticals Co |
Composiciones que actuan sobre bcma y metodos de uso de estas
|
|
US20240409934A1
(en)
|
2021-10-25 |
2024-12-12 |
Board Of Regents, The University Of Texas System |
Foxo1-targeted therapy for the treatment of cancer
|
|
AU2022375806A1
(en)
|
2021-10-29 |
2023-12-14 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hematological cancer
|
|
EP4433096A1
(en)
|
2021-11-19 |
2024-09-25 |
Ardeagen Corporation |
Gpc3 binding agents, conjugates thereof and methods of using the same
|
|
KR20240123846A
(ko)
*
|
2021-11-24 |
2024-08-14 |
다나-파버 캔서 인스티튜트 인크. |
Ctla-4에 대한 항체 및 이의 사용 방법
|
|
CA3240822A1
(en)
|
2021-12-17 |
2023-06-22 |
Tony Lee |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
|
TW202332687A
(zh)
|
2021-12-23 |
2023-08-16 |
比利時商ｅＴｈｅＲＮＡ免疫治療公司 |
免疫刺激性mrna組成物及其用途
|
|
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(ko)
|
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2024-09-11 |
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간세포성 암종에 대한 조합 요법
|
|
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(en)
|
2022-02-04 |
2024-12-11 |
Abbott Laboratories |
Lateral flow methods, assays, and devices for detecting the presence or measuring the amount of ubiquitin carboxy-terminal hydrolase l1 and/or glial fibrillary acidic protein in a sample
|
|
MX2024010310A
(es)
|
2022-02-25 |
2024-08-28 |
Bristol Myers Squibb Co |
Terapia de combinacion para carcinoma colorrectal.
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
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Methods of treating a tumor
|
|
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(ko)
|
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2025-01-08 |
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T 세포 가용성을 증가시키기 위한 항-클라우딘-1 항체의 사용
|
|
MX2024011278A
(es)
|
2022-03-15 |
2024-09-25 |
Compugen Ltd |
Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer.
|
|
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(ko)
|
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2024-11-13 |
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다중 특이적 분자와 면역 체크 포인트 저해제의 조합
|
|
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(ko)
|
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2024-11-05 |
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폴리펩티드를 단리하는 방법
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
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Methods of treating tumor
|
|
JP2025512401A
(ja)
|
2022-04-15 |
2025-04-17 |
アイオバンス バイオセラピューティクス，インコーポレイテッド |
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|
|
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(en)
|
2022-04-28 |
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Medical University Of South Carolina |
Chimeric antigen receptor modified regulatory t cells for treating cancer
|
|
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(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
|
|
WO2023213763A1
(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
|
|
CN119255825A
(zh)
|
2022-05-24 |
2025-01-03 |
第一三共株式会社 |
抗-cdh6抗体-药物缀合物的剂量方案
|
|
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(ko)
|
2022-06-02 |
2025-02-14 |
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항체 조성물 및 이의 이용 방법
|
|
TW202423482A
(zh)
|
2022-06-08 |
2024-06-16 |
美商泰德治療公司 |
可電離陽離子脂質和脂質奈米顆粒、及其合成方法和用途
|
|
WO2024006876A1
(en)
|
2022-06-29 |
2024-01-04 |
Abbott Laboratories |
Magnetic point-of-care systems and assays for determining gfap in biological samples
|
|
GB202209518D0
(en)
|
2022-06-29 |
2022-08-10 |
Snipr Biome Aps |
Treating & preventing E coli infections
|
|
CN119654339A
(zh)
|
2022-07-01 |
2025-03-18 |
特兰斯吉恩股份有限公司 |
包含表面活性蛋白-d和tnfsf成员的融合蛋白
|
|
AU2023313120A1
(en)
|
2022-07-28 |
2025-02-06 |
Astrazeneca Uk Limited |
Combination of antibody-drug conjugate and bispecific checkpoint inhibitor
|
|
WO2024028794A1
(en)
|
2022-08-02 |
2024-02-08 |
Temple Therapeutics BV |
Methods for treating endometrial and ovarian hyperproliferative disorders
|
|
EP4583860A1
(en)
|
2022-09-06 |
2025-07-16 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
|
KR20250068723A
(ko)
|
2022-09-15 |
2025-05-16 |
아보트 러보러터리즈 |
경증 및 초경증 외상성 뇌 손상을 구분하기 위한 바이오마커 및 방법
|
|
WO2024086827A2
(en)
|
2022-10-20 |
2024-04-25 |
Repertoire Immune Medicines, Inc. |
Cd8 t cell targeted il2
|
|
CN120584182A
(zh)
|
2022-11-21 |
2025-09-02 |
艾欧凡斯生物治疗公司 |
肿瘤浸润淋巴细胞扩增的二维过程及其疗法
|
|
IL321098A
(en)
|
2022-12-14 |
2025-07-01 |
Astellas Pharma Europe Bv |
Combination therapy including bispecific binding agents that bind to CLDN18.2- and CD3- and immune checkpoint inhibitors
|
|
AU2023409221A1
(en)
|
2022-12-21 |
2025-06-12 |
Bristol-Myers Squibb Company |
Combination therapy for lung cancer
|
|
WO2024163477A1
(en)
|
2023-01-31 |
2024-08-08 |
University Of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024211475A1
(en)
|
2023-04-04 |
2024-10-10 |
Abbott Laboratories |
Use of biomarkers to determine whether a subject has sustained, may have sustained or is suspected of sustaining a subacute acquired brain injury (abi)
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
WO2024226971A1
(en)
|
2023-04-28 |
2024-10-31 |
Abbott Point Of Care Inc. |
Improved assays, cartridges, and kits for detection of biomarkers, including brain injury biomarkers
|
|
WO2024261302A1
(en)
|
2023-06-22 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Nlrp3 inhibitors, pak1/2 inhibitors and/or caspase 1 inhibitors for use in the treatment of rac2 monogenic disorders
|
|
WO2025003193A1
(en)
|
2023-06-26 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Sertraline and indatraline for disrupting intracellular cholesterol trafficking and subsequently inducing lysosomal damage and anti-tumor immunity
|
|
TW202515608A
(zh)
|
2023-06-26 |
2025-04-16 |
以色列商坎布根有限公司 |
Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途
|
|
EP4484445A1
(en)
|
2023-06-26 |
2025-01-01 |
Universität zu Köln |
Hcmv neutralizing antibodies
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
WO2025050009A2
(en)
|
2023-09-01 |
2025-03-06 |
Children's Hospital Medical Center |
Identification of targets for immunotherapy in melanoma using splicing-derived neoantigens
|
|
EP4590714A1
(en)
|
2023-09-21 |
2025-07-30 |
Domain Therapeutics |
Anti-ccr8 monoclonal antibodies and their therapeutic use
|
|
WO2025061994A1
(en)
|
2023-09-21 |
2025-03-27 |
Domain Therapeutics |
Anti-ccr8 monoclonal antibodies and their therapeutic use
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
EP4574165A1
(en)
|
2023-12-21 |
2025-06-25 |
Egle Therapeutics |
Immunocytokine for cancer treatment
|
|
WO2025133175A1
(en)
|
2023-12-21 |
2025-06-26 |
Egle Therapeutics |
Immunocytokine for cancer treatment
|
|
WO2025145207A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg-depleting agent
|
|
WO2025174825A2
(en)
|
2024-02-12 |
2025-08-21 |
Aera Therapeutics, Inc. |
Delivery compositions
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
US20250269052A1
(en)
|
2024-02-27 |
2025-08-28 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|