JPS6023084B2 - 代用血液 - Google Patents

代用血液

Info

Publication number
JPS6023084B2
JPS6023084B2 JP54087910A JP8791079A JPS6023084B2 JP S6023084 B2 JPS6023084 B2 JP S6023084B2 JP 54087910 A JP54087910 A JP 54087910A JP 8791079 A JP8791079 A JP 8791079A JP S6023084 B2 JPS6023084 B2 JP S6023084B2
Authority
JP
Japan
Prior art keywords
hemoglobin
polyethylene glycol
mol
moles
molecular weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54087910A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5612308A (en
Inventor
雄二 岩下
勝美 鯵坂
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP54087910A priority Critical patent/JPS6023084B2/ja
Priority to GB8022583A priority patent/GB2055868B/en
Priority to US06/167,360 priority patent/US4301144A/en
Priority to CA000356067A priority patent/CA1146858A/en
Priority to DE19803026398 priority patent/DE3026398A1/de
Priority to FR8015568A priority patent/FR2460674A1/fr
Publication of JPS5612308A publication Critical patent/JPS5612308A/ja
Publication of JPS6023084B2 publication Critical patent/JPS6023084B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP54087910A 1979-07-11 1979-07-11 代用血液 Expired JPS6023084B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP54087910A JPS6023084B2 (ja) 1979-07-11 1979-07-11 代用血液
GB8022583A GB2055868B (en) 1979-07-11 1980-07-10 Blood substitute containing hemoglobin
US06/167,360 US4301144A (en) 1979-07-11 1980-07-10 Blood substitute containing modified hemoglobin
CA000356067A CA1146858A (en) 1979-07-11 1980-07-11 Blood substitute containing modified hemoglobin
DE19803026398 DE3026398A1 (de) 1979-07-11 1980-07-11 Modifiziertes haemoglobin enthaltender blutersatz
FR8015568A FR2460674A1 (fr) 1979-07-11 1980-07-11 Succedane du sang contenant de l'hemoglobine modifiee

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54087910A JPS6023084B2 (ja) 1979-07-11 1979-07-11 代用血液

Publications (2)

Publication Number Publication Date
JPS5612308A JPS5612308A (en) 1981-02-06
JPS6023084B2 true JPS6023084B2 (ja) 1985-06-05

Family

ID=13928063

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54087910A Expired JPS6023084B2 (ja) 1979-07-11 1979-07-11 代用血液

Country Status (6)

Country Link
US (1) US4301144A (OSRAM)
JP (1) JPS6023084B2 (OSRAM)
CA (1) CA1146858A (OSRAM)
DE (1) DE3026398A1 (OSRAM)
FR (1) FR2460674A1 (OSRAM)
GB (1) GB2055868B (OSRAM)

Families Citing this family (906)

* Cited by examiner, † Cited by third party
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JPS5959629A (ja) * 1982-09-27 1984-04-05 Nippon Chem Res Kk 効力持続性組成物
JPS59104323A (ja) * 1982-12-07 1984-06-16 Ajinomoto Co Inc 代用血液
DE3340592A1 (de) * 1983-11-10 1985-05-23 B. Braun Melsungen Ag, 3508 Melsungen Konjugate makromolekularer verbindungen an haemoglobine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
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US4598064A (en) * 1984-06-27 1986-07-01 University Of Iowa Research Foundation Alpha-alpha cross-linked hemoglobins
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US4301144A (en) 1981-11-17
DE3026398C2 (OSRAM) 1990-09-13
FR2460674A1 (fr) 1981-01-30
JPS5612308A (en) 1981-02-06
GB2055868B (en) 1983-04-07
FR2460674B1 (OSRAM) 1983-06-24
GB2055868A (en) 1981-03-11
DE3026398A1 (de) 1981-03-26

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