|
JPS57206622A
(en)
*
|
1981-06-10 |
1982-12-18 |
Ajinomoto Co Inc |
Blood substitute
|
|
JPS5959629A
(ja)
*
|
1982-09-27 |
1984-04-05 |
Nippon Chem Res Kk |
効力持続性組成物
|
|
JPS58225025A
(ja)
*
|
1982-06-24 |
1983-12-27 |
Nippon Chem Res Kk |
効力持続性組成物
|
|
JPS59104323A
(ja)
*
|
1982-12-07 |
1984-06-16 |
Ajinomoto Co Inc |
代用血液
|
|
DE3340592A1
(de)
*
|
1983-11-10 |
1985-05-23 |
B. Braun Melsungen Ag, 3508 Melsungen |
Konjugate makromolekularer verbindungen an haemoglobine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
|
|
US4598064A
(en)
*
|
1984-06-27 |
1986-07-01 |
University Of Iowa Research Foundation |
Alpha-alpha cross-linked hemoglobins
|
|
US4600531A
(en)
*
|
1984-06-27 |
1986-07-15 |
University Of Iowa Research Foundation |
Production of alpha-alpha cross-linked hemoglobins in high yield
|
|
USRE34271E
(en)
*
|
1984-06-27 |
1993-06-01 |
University Of Iowa Research Foundation |
Production of alpha-alpha cross-linked hemoglobins in high yield
|
|
JPS6153223A
(ja)
*
|
1984-08-22 |
1986-03-17 |
Ajinomoto Co Inc |
ヘモグロビン−ポリアルキレングリコ−ル結合体の製造方法
|
|
EP0206448B1
(en)
*
|
1985-06-19 |
1990-11-14 |
Ajinomoto Co., Inc. |
Hemoglobin combined with a poly(alkylene oxide)
|
|
US4917888A
(en)
*
|
1985-06-26 |
1990-04-17 |
Cetus Corporation |
Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation
|
|
US5206344A
(en)
*
|
1985-06-26 |
1993-04-27 |
Cetus Oncology Corporation |
Interleukin-2 muteins and polymer conjugation thereof
|
|
US4766106A
(en)
*
|
1985-06-26 |
1988-08-23 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polymer conjugation
|
|
US4791192A
(en)
*
|
1986-06-26 |
1988-12-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified protein with polyethyleneglycol
|
|
US5449759A
(en)
*
|
1987-05-16 |
1995-09-12 |
Somatogen, Inc. |
Hemoglobins with intersubunit desulfide bonds
|
|
US5336603A
(en)
*
|
1987-10-02 |
1994-08-09 |
Genentech, Inc. |
CD4 adheson variants
|
|
US6710169B2
(en)
*
|
1987-10-02 |
2004-03-23 |
Genentech, Inc. |
Adheson variants
|
|
US4847325A
(en)
*
|
1988-01-20 |
1989-07-11 |
Cetus Corporation |
Conjugation of polymer to colony stimulating factor-1
|
|
US5565519A
(en)
*
|
1988-11-21 |
1996-10-15 |
Collagen Corporation |
Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
|
|
US5306500A
(en)
*
|
1988-11-21 |
1994-04-26 |
Collagen Corporation |
Method of augmenting tissue with collagen-polymer conjugates
|
|
US5510418A
(en)
*
|
1988-11-21 |
1996-04-23 |
Collagen Corporation |
Glycosaminoglycan-synthetic polymer conjugates
|
|
US5162430A
(en)
*
|
1988-11-21 |
1992-11-10 |
Collagen Corporation |
Collagen-polymer conjugates
|
|
US5166322A
(en)
*
|
1989-04-21 |
1992-11-24 |
Genetics Institute |
Cysteine added variants of interleukin-3 and chemical modifications thereof
|
|
US5312808A
(en)
*
|
1989-11-22 |
1994-05-17 |
Enzon, Inc. |
Fractionation of polyalkylene oxide-conjugated hemoglobin solutions
|
|
US5650388A
(en)
*
|
1989-11-22 |
1997-07-22 |
Enzon, Inc. |
Fractionated polyalkylene oxide-conjugated hemoglobin solutions
|
|
US5234903A
(en)
*
|
1989-11-22 |
1993-08-10 |
Enzon, Inc. |
Chemically modified hemoglobin as an effective, stable non-immunogenic red blood cell substitute
|
|
US6172039B1
(en)
|
1990-04-16 |
2001-01-09 |
Apex Bioscience, Inc. |
Expression of recombinant hemoglobin and hemoglobin variants in yeast
|
|
US5239061A
(en)
*
|
1990-06-20 |
1993-08-24 |
Research Corporation Technologies, Inc. |
Modified human hemoglobin, blood substitutes containing the same, and vectors for expressing the modified hemoglobin
|
|
US5248766A
(en)
*
|
1990-08-17 |
1993-09-28 |
Baxter International Inc. |
Oxirane-modified hemoglobin based composition
|
|
US5595732A
(en)
*
|
1991-03-25 |
1997-01-21 |
Hoffmann-La Roche Inc. |
Polyethylene-protein conjugates
|
|
WO1992020371A1
(en)
|
1991-05-10 |
1992-11-26 |
Celtrix Pharmaceuticals, Inc. |
Targeted delivery of bone growth factors
|
|
US5334705A
(en)
*
|
1991-08-15 |
1994-08-02 |
Duke University |
Benzenetricarboxylate derivative-crosslinked low oxygen affinity hemoglobin
|
|
EP0611306B1
(en)
*
|
1991-11-08 |
1998-07-08 |
Somatogen, Inc. |
Hemoglobins as drug delivery agents
|
|
US5344393A
(en)
*
|
1992-02-28 |
1994-09-06 |
Alliance Pharmaceutical Corp. |
Use of synthetic oxygen carriers to facilitate oxygen delivery
|
|
US6187744B1
(en)
|
1992-03-11 |
2001-02-13 |
Michael W. Rooney |
Methods and compositions for regulating the intravascular flow and oxygenating activity of hemoglobin in a human or animal subject
|
|
US5382657A
(en)
*
|
1992-08-26 |
1995-01-17 |
Hoffmann-La Roche Inc. |
Peg-interferon conjugates
|
|
US5612310A
(en)
*
|
1993-05-24 |
1997-03-18 |
Duke University |
Methods for improving therapeutic effectiveness of agents for the treatment of solid tumors and other disorders
|
|
US5554638A
(en)
*
|
1993-05-24 |
1996-09-10 |
Duke University |
Methods for improving therapeutic effectiveness of agents for the treatment of solid tumors and other disorders
|
|
US5578564A
(en)
*
|
1993-07-23 |
1996-11-26 |
Somatogen, Inc. |
Nickel-free hemoglobin and methods for producing such hemoglobin
|
|
US5840851A
(en)
*
|
1993-07-23 |
1998-11-24 |
Plomer; J. Jeffrey |
Purification of hemoglobin
|
|
US5804561A
(en)
*
|
1993-08-16 |
1998-09-08 |
Hsia; Jen-Chang |
Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
|
|
TW381022B
(en)
|
1993-08-16 |
2000-02-01 |
Hsia Jen Chang |
Compositions and methods utilizing nitroxides to avoid oxygen toxicity, particularly in stabilized, polymerized, conjugated, or encapsulated hemoglobin used as a red cell substitute
|
|
US5741893A
(en)
*
|
1993-08-16 |
1998-04-21 |
Hsia; Jen-Chang |
Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
|
|
US5767089A
(en)
*
|
1993-08-16 |
1998-06-16 |
Hsia; Jen-Chang |
Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
|
|
US5817632A
(en)
*
|
1993-08-16 |
1998-10-06 |
Hsia; Jen-Chang |
Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
|
|
US5725839A
(en)
*
|
1993-08-16 |
1998-03-10 |
Hsia; Jen-Chang |
Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules for ERI or MRI
|
|
US5840701A
(en)
*
|
1993-08-16 |
1998-11-24 |
Hsia; Jen-Chang |
Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
|
|
US5824781A
(en)
*
|
1993-08-16 |
1998-10-20 |
Hsia; Jen-Chang |
Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
|
|
US5807831A
(en)
*
|
1993-08-16 |
1998-09-15 |
Hsia; Jen-Chang |
Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
|
|
US5665869A
(en)
*
|
1993-11-15 |
1997-09-09 |
Somatogen, Inc. |
Method for the rapid removal of protoporphyrin from protoporphyrin IX-containing solutions of hemoglobin
|
|
US6242417B1
(en)
|
1994-03-08 |
2001-06-05 |
Somatogen, Inc. |
Stabilized compositions containing hemoglobin
|
|
US5631219A
(en)
*
|
1994-03-08 |
1997-05-20 |
Somatogen, Inc. |
Method of stimulating hematopoiesis with hemoglobin
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
GEP20002180B
(en)
*
|
1994-03-31 |
2000-07-25 |
Amgen Inc |
Composition and Methods for Stimulating Megakaryocyte Growth and Differentiation
|
|
US5795569A
(en)
*
|
1994-03-31 |
1998-08-18 |
Amgen Inc. |
Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
|
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
|
DE4423131A1
(de)
*
|
1994-07-01 |
1996-01-04 |
Bayer Ag |
Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4
|
|
US6306454B1
(en)
*
|
1994-10-17 |
2001-10-23 |
Baxter International Inc. |
Method for producing improved medical devices and devices so produced
|
|
US5585484A
(en)
*
|
1995-04-19 |
1996-12-17 |
Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University |
Hemoglobin crosslinkers
|
|
US6083913A
(en)
|
1995-06-07 |
2000-07-04 |
Glaxo Wellcome Inc. |
Peptides and compounds that bind to a thrombopoietin receptor
|
|
US5869451A
(en)
|
1995-06-07 |
1999-02-09 |
Glaxo Group Limited |
Peptides and compounds that bind to a receptor
|
|
US5865784A
(en)
*
|
1995-06-07 |
1999-02-02 |
Alliance Pharmaceutical Corp. |
Method of hemodilution facilitated by monitoring oxygenation status
|
|
US6833408B2
(en)
|
1995-12-18 |
2004-12-21 |
Cohesion Technologies, Inc. |
Methods for tissue repair using adhesive materials
|
|
WO1997022371A1
(en)
|
1995-12-18 |
1997-06-26 |
Collagen Corporation |
Crosslinked polymer compositions and methods for their use
|
|
US6458889B1
(en)
|
1995-12-18 |
2002-10-01 |
Cohesion Technologies, Inc. |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
|
US7883693B2
(en)
|
1995-12-18 |
2011-02-08 |
Angiodevice International Gmbh |
Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
|
|
US6046048A
(en)
*
|
1996-01-09 |
2000-04-04 |
Genetech, Inc. |
Apo-2 ligand
|
|
US6998116B1
(en)
|
1996-01-09 |
2006-02-14 |
Genentech, Inc. |
Apo-2 ligand
|
|
US20050089958A1
(en)
*
|
1996-01-09 |
2005-04-28 |
Genentech, Inc. |
Apo-2 ligand
|
|
US6030945A
(en)
*
|
1996-01-09 |
2000-02-29 |
Genentech, Inc. |
Apo-2 ligand
|
|
US20020165157A1
(en)
*
|
1996-04-01 |
2002-11-07 |
Genentech, Inc. |
Apo-2LI and Apo-3 polypeptides
|
|
CA2249206A1
(en)
|
1996-04-01 |
1997-10-09 |
Genentech, Inc. |
Apo-2li and apo-3 apoptosis polypeptides
|
|
US7091311B2
(en)
*
|
1996-06-07 |
2006-08-15 |
Smithkline Beecham Corporation |
Peptides and compounds that bind to a receptor
|
|
US6159462A
(en)
*
|
1996-08-16 |
2000-12-12 |
Genentech, Inc. |
Uses of Wnt polypeptides
|
|
US5851984A
(en)
*
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
|
US6462176B1
(en)
|
1996-09-23 |
2002-10-08 |
Genentech, Inc. |
Apo-3 polypeptide
|
|
US20040241645A1
(en)
*
|
1997-01-31 |
2004-12-02 |
Genentech, Inc. |
O-fucosyltransferase
|
|
DE69737457T2
(de)
|
1997-01-31 |
2007-11-29 |
Genentech, Inc., South San Francisco |
O-fukosyltransferase
|
|
US5814601A
(en)
*
|
1997-02-28 |
1998-09-29 |
The Regents Of The University Of California |
Methods and compositions for optimization of oxygen transport by cell-free systems
|
|
ATE302019T1
(de)
*
|
1997-02-28 |
2005-09-15 |
Univ California |
Verfahren und zusammensetzungen zur optimierung des sauerstofftransportes in zellfreien systemen
|
|
US20020102706A1
(en)
*
|
1997-06-18 |
2002-08-01 |
Genentech, Inc. |
Apo-2DcR
|
|
KR100816621B1
(ko)
|
1997-04-07 |
2008-03-24 |
제넨테크, 인크. |
항-vegf 항체
|
|
PT971959E
(pt)
|
1997-04-07 |
2006-05-31 |
Genentech Inc |
Anticorpos humanizados e metodos para formar anticorpos humanizados
|
|
US20100152426A1
(en)
*
|
1997-05-15 |
2010-06-17 |
Ashkenazi Avi J |
Apo-2 receptor fusion proteins
|
|
US6342369B1
(en)
*
|
1997-05-15 |
2002-01-29 |
Genentech, Inc. |
Apo-2-receptor
|
|
ES2293682T5
(es)
|
1997-05-15 |
2011-11-17 |
Genentech, Inc. |
Anticuerpo anti-apo2.
|
|
US6291643B1
(en)
|
1997-06-05 |
2001-09-18 |
Board Of Reports, The University Of Texas System |
Apaf-1 an activator of caspase-3
|
|
IL133122A0
(en)
|
1997-06-18 |
2001-03-19 |
Genentech Inc |
Apo-2dcr polypeptides
|
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
|
AU8485098A
(en)
*
|
1997-08-26 |
1999-03-16 |
Genentech Inc. |
Rtd receptor
|
|
US20030175856A1
(en)
*
|
1997-08-26 |
2003-09-18 |
Genetech, Inc. |
Rtd receptor
|
|
CA2382409A1
(en)
|
1997-09-17 |
1999-03-25 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20040231011A1
(en)
*
|
2001-06-28 |
2004-11-18 |
Genentech, Inc. |
DcR3 polypeptide, a TNFR homolog
|
|
JP4303883B2
(ja)
|
1997-09-18 |
2009-07-29 |
ジェネンテック・インコーポレーテッド |
DcR3ポリペプチドというTNFR相同体
|
|
EP1021542B1
(en)
|
1997-10-10 |
2009-03-04 |
Genentech, Inc. |
Apo-3 ligand
|
|
DK1027437T3
(da)
|
1997-10-29 |
2008-11-24 |
Genentech Inc |
Anvendelse af det WNT-1 inducerede udskilte polypeptid WISP-1
|
|
JP2001520885A
(ja)
|
1997-10-29 |
2001-11-06 |
ジェネンテック・インコーポレーテッド |
Wnt−1誘導遺伝子
|
|
US7192589B2
(en)
|
1998-09-16 |
2007-03-20 |
Genentech, Inc. |
Treatment of inflammatory disorders with STIgMA immunoadhesins
|
|
ATE410512T1
(de)
|
1997-11-21 |
2008-10-15 |
Genentech Inc |
Plättchen-spezifische antigene und deren pharmazeutische verwendung
|
|
JP2002508962A
(ja)
|
1998-01-15 |
2002-03-26 |
ジェネンテク・インコーポレイテッド |
Apo−2リガンド
|
|
NZ525914A
(en)
|
1998-03-10 |
2004-03-26 |
Genentech Inc |
Novel polypeptides and nucleic acids encoding the same
|
|
ATE405651T1
(de)
|
1998-03-17 |
2008-09-15 |
Genentech Inc |
Zu vegf und bmp1 homologe polypeptide
|
|
EP1865061A3
(en)
|
1998-05-15 |
2007-12-19 |
Genentech, Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
|
AU740405B2
(en)
|
1998-05-15 |
2001-11-01 |
Genentech Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
|
EP3112468A1
(en)
|
1998-05-15 |
2017-01-04 |
Genentech, Inc. |
Il-17 homologous polypeptides and therapeutic uses thereof
|
|
WO2001060397A1
(en)
|
2000-02-16 |
2001-08-23 |
Genentech, Inc. |
Uses of agonists and antagonists to modulate activity of tnf-related molecules
|
|
ATE443723T1
(de)
*
|
1998-06-12 |
2009-10-15 |
Genentech Inc |
Monoklonale antikörper, kreuz-reaktive antikörper und deren produktionsverfahren
|
|
US20020172678A1
(en)
|
2000-06-23 |
2002-11-21 |
Napoleone Ferrara |
EG-VEGF nucleic acids and polypeptides and methods of use
|
|
MEP42108A
(en)
*
|
1998-10-23 |
2011-02-10 |
Kiren Amgen Inc |
Dimeric thrombopoietin peptide mimetics binding to mp1 receptor and having thrombopoietic activity
|
|
EP1950300A3
(en)
|
1998-11-18 |
2011-03-23 |
Genentech, Inc. |
Antibody variants with higher binding affinity compared to parent antibodies
|
|
AUPP785098A0
(en)
|
1998-12-21 |
1999-01-21 |
Victor Chang Cardiac Research Institute, The |
Treatment of heart disease
|
|
EP2075335A3
(en)
|
1998-12-22 |
2009-09-30 |
Genentech, Inc. |
Methods and compositions for inhibiting neoplastic cell growth
|
|
EP1141299A2
(en)
|
1998-12-23 |
2001-10-10 |
Genentech, Inc. |
Il-1 related polypeptides
|
|
JP2000230000A
(ja)
*
|
1999-02-08 |
2000-08-22 |
Hokkaido Univ |
一酸化窒素代謝物−ポリオキシアルキレン−ヘモグロビン結合体
|
|
CA2266174A1
(en)
*
|
1999-03-18 |
2000-09-18 |
Hemosol Inc. |
Hemoglobin-antioxidant conjugates
|
|
KR100316154B1
(ko)
*
|
1999-03-26 |
2001-12-12 |
노광 |
폴리에틸렌글리콜-헤모글로빈 결합체
|
|
WO2000061746A1
(en)
|
1999-04-12 |
2000-10-19 |
Agensys, Inc. |
13 transmembrane protein expressed in prostate cancer
|
|
EP1792989A1
(en)
|
1999-04-12 |
2007-06-06 |
Agensys, Inc. |
13 Transmembrane protein expressed in prostate cancer
|
|
US6635249B1
(en)
|
1999-04-23 |
2003-10-21 |
Cenes Pharmaceuticals, Inc. |
Methods for treating congestive heart failure
|
|
DE60043367D1
(de)
|
1999-06-15 |
2009-12-31 |
Genentech Inc |
Sekretierte und Transmembran-Polypeptide sowie Nukleinsäuren zu deren Kodierung
|
|
PT1200590E
(pt)
|
1999-08-12 |
2009-03-24 |
Agensys Inc |
Antigénio transmembranar lectina tipo c expresso em cancro da próstata humano e utilizações do mesmo
|
|
US7459540B1
(en)
*
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
HK1048494B
(en)
|
1999-10-05 |
2009-06-12 |
Agensys, Inc. |
G protein-coupled receptor up-regulated in prostate cancer and uses thereof
|
|
US6180598B1
(en)
|
1999-10-07 |
2001-01-30 |
Deanna J. Nelson |
Covalently modified hemoglobin having low temperature-dependent oxygen-binding function
|
|
US7668658B2
(en)
|
1999-10-13 |
2010-02-23 |
Sequenom, Inc. |
Methods for generating databases and databases for identifying polymorphic genetic markers
|
|
US6893818B1
(en)
*
|
1999-10-28 |
2005-05-17 |
Agensys, Inc. |
Gene upregulated in cancers of the prostate
|
|
IL149340A0
(en)
|
1999-11-18 |
2002-11-10 |
Corvas Int Inc |
Nucleic acids encoding endotheliases, endotheliases and uses thereof
|
|
US6703480B1
(en)
|
1999-11-24 |
2004-03-09 |
Palani Balu |
Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use
|
|
CA2491433A1
(en)
|
1999-12-01 |
2001-06-07 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7109299B1
(en)
|
1999-12-16 |
2006-09-19 |
Affymax, Inc. |
Peptides and compounds that bind to the IL-5 receptor
|
|
DK1897945T3
(da)
|
1999-12-23 |
2012-05-07 |
Genentech Inc |
IL-17 homologe polypeptider og terapeutiske anvendelser deraf.
|
|
US7700341B2
(en)
|
2000-02-03 |
2010-04-20 |
Dendreon Corporation |
Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
|
|
US7101974B2
(en)
|
2000-03-02 |
2006-09-05 |
Xencor |
TNF-αvariants
|
|
US6740520B2
(en)
*
|
2000-03-21 |
2004-05-25 |
Genentech, Inc. |
Cytokine receptor and nucleic acids encoding the same
|
|
US20040086970A1
(en)
*
|
2000-03-22 |
2004-05-06 |
Genentech, Inc. |
Novel cytokine receptors and nucleic acids encoding the same
|
|
WO2004043361A2
(en)
|
2002-11-08 |
2004-05-27 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
|
US6667300B2
(en)
*
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
|
EP2275549A1
(en)
|
2000-06-23 |
2011-01-19 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
CA2648046A1
(en)
|
2000-06-23 |
2002-01-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
DE10031740A1
(de)
|
2000-06-29 |
2002-02-14 |
Sanguibio Tech Ag |
Künstliche Sauerstoffträger aus vernetztem modifizierten Human- oder Schweinehämoglobin mit verbesserten Eigenschaften, Verfahren zu ihrer technisch einfachen Herstellung aus gereinigtem Material in hohen Ausbeuten, sowie deren Verwendung
|
|
DE10031744A1
(de)
|
2000-06-29 |
2002-01-17 |
Sanguibio Tech Ag |
Mit Blutplasma verträgliche, vernetzte und mit Polyalkylenoxiden konjugierte Säugetierhämoglobine als künstliche medizinische Sauerstoffträger, ihre Herstellung und ihre Verwendung
|
|
FR2811323B1
(fr)
*
|
2000-07-07 |
2006-10-06 |
Fuma Tech Gmbh |
Materiau hybride, utilisation dudit materiau hybride et procede de sa fabrication
|
|
ATE412009T1
(de)
|
2000-08-24 |
2008-11-15 |
Genentech Inc |
Methode zur inhibierung von il-22 induziertem pap1
|
|
CA2705366A1
(en)
|
2000-08-28 |
2002-03-07 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled 85p1b3 useful in treatment and detection of cancer
|
|
EP1944317A3
(en)
|
2000-09-01 |
2008-09-17 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20020115058A1
(en)
*
|
2000-09-22 |
2002-08-22 |
Pedersen Finn Skou |
Methods for diagnosis and treatment of diseases associated with altered expression of Pik3r1
|
|
US20030044803A1
(en)
*
|
2000-09-22 |
2003-03-06 |
Pedersen Finn Skou |
Methods for diagnosis and treatment of diseases associated with altered expression of JAK1
|
|
US20020164576A1
(en)
*
|
2000-09-22 |
2002-11-07 |
Pedersen Finn Skou |
Methods for diagnosis and treatment of diseases associated with altered expression of Nrf2
|
|
US6576452B1
(en)
|
2000-10-04 |
2003-06-10 |
Genencor International, Inc. |
2,5-diketo-L-gluconic acid reductases and methods of use
|
|
US6673580B2
(en)
|
2000-10-27 |
2004-01-06 |
Genentech, Inc. |
Identification and modification of immunodominant epitopes in polypeptides
|
|
US6747132B2
(en)
|
2000-11-29 |
2004-06-08 |
Apex Biosciences, Inc. |
Methods for the synthesis of a modified hemoglobin solution
|
|
US7892730B2
(en)
|
2000-12-22 |
2011-02-22 |
Sagres Discovery, Inc. |
Compositions and methods for cancer
|
|
US7820447B2
(en)
|
2000-12-22 |
2010-10-26 |
Sagres Discovery Inc. |
Compositions and methods for cancer
|
|
US20030165878A1
(en)
*
|
2000-12-22 |
2003-09-04 |
Morris David W. |
Novel compositions and methods in cancer associated with altered expression of MCM3AP
|
|
US20030087252A1
(en)
*
|
2000-12-22 |
2003-05-08 |
Morris David W. |
Novel compositions and methods in cancer associated with altered expression of PRDM11
|
|
US7700274B2
(en)
*
|
2000-12-22 |
2010-04-20 |
Sagres Discovery, Inc. |
Compositions and methods in cancer associated with altered expression of KCNJ9
|
|
US20030099963A1
(en)
*
|
2000-12-22 |
2003-05-29 |
Morris David W. |
Novel compositions and methods in cancer associated with altered expression of TBX21
|
|
US20030232334A1
(en)
|
2000-12-22 |
2003-12-18 |
Morris David W. |
Novel compositions and methods for cancer
|
|
US7645441B2
(en)
*
|
2000-12-22 |
2010-01-12 |
Sagres Discovery Inc. |
Compositions and methods in cancer associated with altered expression of PRLR
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7087726B2
(en)
|
2001-02-22 |
2006-08-08 |
Genentech, Inc. |
Anti-interferon-α antibodies
|
|
US6924358B2
(en)
|
2001-03-05 |
2005-08-02 |
Agensys, Inc. |
121P1F1: a tissue specific protein highly expressed in various cancers
|
|
WO2002072786A2
(en)
|
2001-03-13 |
2002-09-19 |
Corvas International, Inc. |
Nucleic acid molecules encoding a transmembrane serine protease 7, the encoded polypeptides and methods based thereon
|
|
US7271240B2
(en)
|
2001-03-14 |
2007-09-18 |
Agensys, Inc. |
125P5C8: a tissue specific protein highly expressed in various cancers
|
|
AU2002254357A1
(en)
|
2001-03-22 |
2002-10-08 |
Dendreon Corporation |
Nucleic acid molecules encoding serine protease cvsp14, the encoded polypeptides and methods based thereon
|
|
CA2442089A1
(en)
|
2001-03-27 |
2002-10-03 |
Dendreon San Diego Llc |
Nucleic acid molecules encoding a transmembran serine protease 9, the encoded polypeptides and methods based thereon
|
|
WO2002083921A2
(en)
|
2001-04-10 |
2002-10-24 |
Agensys, Inc. |
Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers
|
|
US20030191073A1
(en)
|
2001-11-07 |
2003-10-09 |
Challita-Eid Pia M. |
Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer
|
|
US7112430B2
(en)
|
2001-05-14 |
2006-09-26 |
Dendreon Corporation |
Nucleic acid molecules encoding a transmembrane serine protease 10, the encoded polypeptides and methods based thereon
|
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
|
PT2000545E
(pt)
|
2001-06-20 |
2011-12-21 |
Genentech Inc |
Composições e métodos para o diagnóstico e tratamento do tumor pulmonar
|
|
AU2002320628A1
(en)
|
2001-07-19 |
2003-03-03 |
Albert Einstein College Of Medecine Of Yeshiva University |
Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy akylene glycols
|
|
BR0211614A
(pt)
*
|
2001-08-03 |
2006-10-31 |
Genentech Inc |
polipeptìdeo tacis e br3 e empregos dos mesmos
|
|
EP2311960A3
(en)
|
2001-08-29 |
2011-06-01 |
Genentech, Inc. |
Bv8 nucleic acids and polypeptides with mitogenic activity
|
|
US20040235068A1
(en)
*
|
2001-09-05 |
2004-11-25 |
Levinson Arthur D. |
Methods for the identification of polypeptide antigens associated with disorders involving aberrant cell proliferation and compositions useful for the treatment of such disorders
|
|
EP2287186B1
(en)
|
2001-09-06 |
2014-12-31 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
|
|
DE60238143D1
(de)
|
2001-09-18 |
2010-12-09 |
Genentech Inc |
Zusammensetzungen und verfahren für die diagnose von tumoren
|
|
US20070098728A1
(en)
*
|
2001-09-24 |
2007-05-03 |
Pedersen Finn S |
Novel compositions and methods in cancer
|
|
US7320789B2
(en)
|
2001-09-26 |
2008-01-22 |
Wyeth |
Antibody inhibitors of GDF-8 and uses thereof
|
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
US20040126762A1
(en)
*
|
2002-12-17 |
2004-07-01 |
Morris David W. |
Novel compositions and methods in cancer
|
|
US20040166490A1
(en)
*
|
2002-12-17 |
2004-08-26 |
Morris David W. |
Novel therapeutic targets in cancer
|
|
AU2002357004A1
(en)
*
|
2001-11-20 |
2003-06-10 |
Dendreon San Diego Llc |
Nucleic acid molecules encoding serine protease 17, the encoded polypeptides and methods based thereon
|
|
US20040197778A1
(en)
*
|
2002-12-26 |
2004-10-07 |
Sagres Discovery, Inc. |
Novel compositions and methods in cancer
|
|
US20060040262A1
(en)
*
|
2002-12-27 |
2006-02-23 |
Morris David W |
Novel compositions and methods in cancer
|
|
US20040180344A1
(en)
*
|
2003-03-14 |
2004-09-16 |
Morris David W. |
Novel therapeutic targets in cancer
|
|
AU2002314790A1
(en)
*
|
2001-12-05 |
2003-06-23 |
Dow Global Technologies Inc. |
Method for immobilizing a biologic in a polyurethane-hydrogel composition, a composition prepared from the method, and biomedical applications
|
|
AU2002367318B2
(en)
|
2002-01-02 |
2007-07-12 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20030153491A1
(en)
|
2002-01-11 |
2003-08-14 |
Winslow Robert M. |
Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
|
|
US20050164915A1
(en)
*
|
2002-04-01 |
2005-07-28 |
Sangart, Inc. |
Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
|
|
BR0307871A
(pt)
|
2002-02-21 |
2005-04-12 |
Wyeth Corp |
Proteìnas contendo domìnio de folistatina
|
|
EP1575480A4
(en)
|
2002-02-22 |
2008-08-06 |
Genentech Inc |
COMPOSITIONS AND METHODS OF TREATING IMMUNE-INFLAMMATORY DISEASES
|
|
SI1485477T1
(sl)
|
2002-02-25 |
2009-10-31 |
Genentech Inc |
Novi citokinski receptor GLM-R tipa 1
|
|
US20100311954A1
(en)
*
|
2002-03-01 |
2010-12-09 |
Xencor, Inc. |
Optimized Proteins that Target Ep-CAM
|
|
KR100508358B1
(ko)
*
|
2002-03-20 |
2005-08-17 |
주식회사 바이오폴리메드 |
생체적합성 고분자가 시스테인 잔기에 화학양론적으로 결합된 g-csf의 제조 방법
|
|
EP2093233A1
(en)
|
2002-03-21 |
2009-08-26 |
Sagres Discovery, Inc. |
Novel compositions and methods in cancer
|
|
US7452533B2
(en)
*
|
2002-03-26 |
2008-11-18 |
Biosynexus Incorporated |
Antimicrobial polymer conjugate containing lysostaphin and polyethylene glycol
|
|
JP2005536190A
(ja)
|
2002-04-16 |
2005-12-02 |
ジェネンテック・インコーポレーテッド |
腫瘍の診断と治療のための組成物と方法
|
|
WO2003093296A2
(en)
|
2002-05-03 |
2003-11-13 |
Sequenom, Inc. |
Kinase anchor protein muteins, peptides thereof, and related methods
|
|
US7351542B2
(en)
|
2002-05-20 |
2008-04-01 |
The Regents Of The University Of California |
Methods of modulating tubulin deacetylase activity
|
|
US20040001801A1
(en)
*
|
2002-05-23 |
2004-01-01 |
Corvas International, Inc. |
Conjugates activated by cell surface proteases and therapeutic uses thereof
|
|
AU2002304965A1
(en)
|
2002-05-24 |
2003-12-12 |
Zensun (Shanghai) Sci-Tech.Ltd |
Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
|
|
EP2305710A3
(en)
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
EP1553912A4
(en)
*
|
2002-06-07 |
2007-08-08 |
Genentech Inc |
COMPOSITIONS AND METHODS FOR TUMOR DIAGNOSIS AND TREATMENT
|
|
JP3912206B2
(ja)
*
|
2002-07-05 |
2007-05-09 |
株式会社日立製作所 |
筒内直接燃料噴射装置用燃料ポンプ
|
|
WO2004004649A2
(en)
|
2002-07-08 |
2004-01-15 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
WO2004011611A2
(en)
*
|
2002-07-25 |
2004-02-05 |
Genentech, Inc. |
Taci antibodies and uses thereof
|
|
DE60335195D1
(de)
*
|
2002-08-12 |
2011-01-13 |
Danisco Us Inc |
Mutante e. coli-appa-phytaseenzyme und natürliche varianten davon, solche phytaseenzyme codierende nukleinsäuren, diese enthaltende vektoren und wirtszellen und verfahren zur herstellung und verwendung davon
|
|
AU2003243151A1
(en)
|
2002-08-16 |
2004-03-03 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
|
|
WO2004019860A2
(en)
*
|
2002-08-28 |
2004-03-11 |
Pharmacia Corporation |
Formulations of modified antibodies and methods of making the same
|
|
US20040091490A1
(en)
*
|
2002-08-28 |
2004-05-13 |
Robert Johnson |
Stable pH optimized formulation of a modified antibody
|
|
EP1578373A4
(en)
|
2002-09-11 |
2007-10-24 |
Genentech Inc |
NEW COMPOSITIONS AND METHOD FOR THE TREATMENT OF ILLNESSES OF THE IMMUNE SYSTEM
|
|
JP5401001B2
(ja)
|
2002-09-11 |
2014-01-29 |
ジェネンテック, インコーポレイテッド |
免疫関連疾患の治療のための新規組成物と方法
|
|
US20070010434A1
(en)
|
2002-09-16 |
2007-01-11 |
Genetech, Inc. |
Novel compositions and methods for the treatment of immune related diseases
|
|
ES2781475T3
(es)
|
2002-09-18 |
2020-09-02 |
Janssen Pharmaceuticals Inc |
Métodos para aumentar la producción de células madre hematopoyéticas y plaquetas
|
|
CA2499843A1
(en)
|
2002-09-25 |
2004-04-08 |
Genentech, Inc. |
Novel compositions and methods for the treatment of psoriasis
|
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
|
US20040149235A1
(en)
*
|
2002-10-04 |
2004-08-05 |
Pogue Albert S. |
Apparatus and method for removal of waste from animal production facilities
|
|
EP2322200A3
(en)
|
2002-10-29 |
2011-07-27 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
JP2011516026A
(ja)
|
2002-11-26 |
2011-05-26 |
ジェネンテック・インコーポレーテッド |
免疫関連疾患の治療のための組成物と方法
|
|
EP1565200A4
(en)
|
2002-11-27 |
2009-06-24 |
Agensys Inc |
NUCLEIC ACID 24P4C12 AND CORRESPONDING PROTEIN FOR THE TREATMENT AND DETECTION OF CANCER
|
|
WO2004054473A1
(en)
*
|
2002-12-12 |
2004-07-01 |
Baxter International Inc. |
Method for producing medical devices and devices so produced
|
|
GEP20084487B
(en)
*
|
2002-12-26 |
2008-09-25 |
Mountain View Pharmaceuticals |
Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof
|
|
JP5207590B2
(ja)
*
|
2002-12-26 |
2013-06-12 |
マウンテン ビュー ファーマシューティカルズ,インコーポレイテッド |
増強された生物学的能力を有するインターフェロン−βのポリマー結合体
|
|
AU2003300076C1
(en)
|
2002-12-30 |
2010-03-04 |
Angiotech International Ag |
Drug delivery from rapid gelling polymer composition
|
|
US20050221443A1
(en)
*
|
2003-01-06 |
2005-10-06 |
Xencor, Inc. |
Tumor necrosis factor super family agonists
|
|
US20060014248A1
(en)
*
|
2003-01-06 |
2006-01-19 |
Xencor, Inc. |
TNF super family members with altered immunogenicity
|
|
US20050130892A1
(en)
*
|
2003-03-07 |
2005-06-16 |
Xencor, Inc. |
BAFF variants and methods thereof
|
|
US7553930B2
(en)
*
|
2003-01-06 |
2009-06-30 |
Xencor, Inc. |
BAFF variants and methods thereof
|
|
EP1581904A2
(en)
*
|
2003-01-08 |
2005-10-05 |
Xencor, Inc. |
Novel proteins with altered immunogenicity
|
|
JP2007524361A
(ja)
|
2003-02-10 |
2007-08-30 |
アジェンシス, インコーポレイテッド |
膀胱癌及びその他の癌の治療及び検出に有用な名称158p1d7の核酸及び対応タンパク質
|
|
JP2007524362A
(ja)
|
2003-02-14 |
2007-08-30 |
サイグレス ディスカバリー, インコーポレイテッド |
癌における治療gpcr標的
|
|
US20040170982A1
(en)
*
|
2003-02-14 |
2004-09-02 |
Morris David W. |
Novel therapeutic targets in cancer
|
|
US7767387B2
(en)
|
2003-06-13 |
2010-08-03 |
Sagres Discovery, Inc. |
Therapeutic targets in cancer
|
|
US20070218071A1
(en)
*
|
2003-09-15 |
2007-09-20 |
Morris David W |
Novel therapeutic targets in cancer
|
|
JP4912144B2
(ja)
|
2003-03-12 |
2012-04-11 |
ジェネンテック, インコーポレイテッド |
造血促進のためのbv8及び/又はeg−vegfの使用
|
|
NZ542306A
(en)
*
|
2003-03-14 |
2008-04-30 |
Wyeth Corp |
Antibodies against human IL-21 receptor and uses therefor
|
|
US7235639B2
(en)
|
2003-04-23 |
2007-06-26 |
Ezio Panzeri |
Hemoglobin conjugates
|
|
US20050025763A1
(en)
|
2003-05-08 |
2005-02-03 |
Protein Design Laboratories, Inc. |
Therapeutic use of anti-CS1 antibodies
|
|
US7709610B2
(en)
|
2003-05-08 |
2010-05-04 |
Facet Biotech Corporation |
Therapeutic use of anti-CS1 antibodies
|
|
UA101945C2
(uk)
|
2003-05-30 |
2013-05-27 |
Дженентек, Инк. |
Лікування злоякісного новоутворення за допомогою бевацизумабу
|
|
CA2526274C
(en)
|
2003-05-30 |
2015-12-01 |
Agensys, Inc. |
Prostate stem cell antigen (psca) variants and subsequences thereof
|
|
US20050163775A1
(en)
*
|
2003-06-05 |
2005-07-28 |
Genentech, Inc. |
Combination therapy for B cell disorders
|
|
JP2007526220A
(ja)
*
|
2003-06-05 |
2007-09-13 |
ジェネンテック・インコーポレーテッド |
B細胞疾患の併用療法
|
|
US7939058B2
(en)
|
2003-07-03 |
2011-05-10 |
University Of Southern California |
Uses of IL-12 in hematopoiesis
|
|
EP2784084B2
(en)
|
2003-07-08 |
2023-10-04 |
Novartis Pharma AG |
Antagonist antibodies to IL-17A/F heterologous polypeptides
|
|
AR046071A1
(es)
|
2003-07-10 |
2005-11-23 |
Hoffmann La Roche |
Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos
|
|
TWI476206B
(zh)
|
2003-07-18 |
2015-03-11 |
Amgen Inc |
對肝細胞生長因子具專一性之結合劑
|
|
WO2005019258A2
(en)
|
2003-08-11 |
2005-03-03 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
US20050054614A1
(en)
*
|
2003-08-14 |
2005-03-10 |
Diacovo Thomas G. |
Methods of inhibiting leukocyte accumulation
|
|
WO2005016348A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
|
AR045614A1
(es)
*
|
2003-09-10 |
2005-11-02 |
Hoffmann La Roche |
Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos
|
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
|
US20070281896A1
(en)
*
|
2003-09-30 |
2007-12-06 |
Morris David W |
Novel compositions and methods in cancer
|
|
WO2005035569A2
(en)
*
|
2003-10-10 |
2005-04-21 |
Five Prime Therapeutics, Inc. |
Kiaa0779, splice variants thereof, and methods of their use
|
|
EP1675871A2
(en)
|
2003-10-10 |
2006-07-05 |
Xencor Inc. |
Protein based tnf-alpha variants for the treatment of tnf-alpha related disorders
|
|
DK2295073T3
(da)
|
2003-11-17 |
2014-07-28 |
Genentech Inc |
Antistof mod cd22 til behandling af tumor af hæmatopoietisk oprindelse
|
|
SI2311873T1
(sl)
|
2004-01-07 |
2018-12-31 |
Novartis Vaccines And Diagnostics, Inc. |
M-CSF-specifična monoklonska protitelesa in njihova uporaba
|
|
US20050169970A1
(en)
*
|
2004-02-02 |
2005-08-04 |
Unilever Bestfoods, North America |
Food composition with fibers
|
|
EP1740615B1
(en)
|
2004-03-31 |
2014-11-05 |
Genentech, Inc. |
Humanized anti-tgf-beta antibodies
|
|
US7794713B2
(en)
|
2004-04-07 |
2010-09-14 |
Lpath, Inc. |
Compositions and methods for the treatment and prevention of hyperproliferative diseases
|
|
PT1737891E
(pt)
|
2004-04-13 |
2013-04-16 |
Hoffmann La Roche |
Anticorpos anti p-selectina
|
|
EP1586334A1
(en)
*
|
2004-04-15 |
2005-10-19 |
TRASTEC scpa |
G-CSF conjugates with peg
|
|
CN104174071A
(zh)
|
2004-04-28 |
2014-12-03 |
安希奥设备国际有限责任公司 |
用于形成交联生物材料的组合物和系统及关联的制备方法与用途
|
|
WO2005113556A1
(en)
|
2004-05-13 |
2005-12-01 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
|
WO2005117889A1
(en)
*
|
2004-05-25 |
2005-12-15 |
Icos Corporation |
Methods for treating and/or preventing aberrant proliferation of hematopoietic
|
|
NZ551627A
(en)
|
2004-05-28 |
2010-02-26 |
Agensys Inc |
Antibodies and related molecules that bind to PSCA proteins
|
|
US20060014680A1
(en)
*
|
2004-07-13 |
2006-01-19 |
Caiding Xu |
Peptides and compounds that bind to the IL-5 receptor
|
|
US20060024677A1
(en)
|
2004-07-20 |
2006-02-02 |
Morris David W |
Novel therapeutic targets in cancer
|
|
SI1771474T1
(sl)
|
2004-07-20 |
2010-06-30 |
Genentech Inc |
Inhibitorji angiopoetinu podobnega proteina kombinacije in njihova uporaba
|
|
TWI380996B
(zh)
*
|
2004-09-17 |
2013-01-01 |
Hoffmann La Roche |
抗ox40l抗體
|
|
EP1796602A4
(en)
|
2004-09-17 |
2016-10-19 |
Angiotech Pharm Inc |
MULTIFUNCTIONAL COMPOUNDS FOR PRODUCING NETWORKED BIOMATERIALS AND MANUFACTURING AND USE METHOD THEREFOR
|
|
CA2581423A1
(en)
|
2004-09-23 |
2006-03-30 |
Vasgene Therapeutics, Inc. |
Polipeptide compounds for inhibiting angiogenesis and tumor growth
|
|
WO2006036834A2
(en)
*
|
2004-09-24 |
2006-04-06 |
Amgen Inc. |
MODIFIED Fc MOLECULES
|
|
AU2005295640B2
(en)
|
2004-10-15 |
2011-07-28 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Multi-domain amphipathic helical peptides and methods of their use
|
|
AU2005304624B2
(en)
|
2004-11-12 |
2010-10-07 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
DE602005022928D1
(de)
|
2004-11-30 |
2010-09-23 |
Abgenix Inc |
Antikörper gegen gpnmb und ihre verwendungen
|
|
US20060134698A1
(en)
*
|
2004-12-20 |
2006-06-22 |
Evanston Northwestern Healthcare Research Institute |
Methods for treating cardiac disease by modifying an N-terminal domain of troponin I
|
|
US7906625B2
(en)
*
|
2005-01-24 |
2011-03-15 |
Amgen Inc. |
Humanized anti-amyloid antibody
|
|
WO2006089106A2
(en)
*
|
2005-02-17 |
2006-08-24 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
|
RU2413735C2
(ru)
|
2005-03-31 |
2011-03-10 |
Эдженсис, Инк. |
Антитела и родственные молекулы, связывающиеся с белками 161p2f10b
|
|
TW200720289A
(en)
|
2005-04-01 |
2007-06-01 |
Hoffmann La Roche |
Antibodies against CCR5 and uses thereof
|
|
CA2604844A1
(en)
|
2005-04-07 |
2006-10-19 |
Novartis Vaccines And Diagnostics, Inc. |
Cancer-related genes
|
|
EP1865981A2
(en)
|
2005-04-07 |
2007-12-19 |
Chiron Corporation |
Cacna1e in cancer diagnosis, detection and treatment
|
|
US8003108B2
(en)
|
2005-05-03 |
2011-08-23 |
Amgen Inc. |
Sclerostin epitopes
|
|
US7592429B2
(en)
|
2005-05-03 |
2009-09-22 |
Ucb Sa |
Sclerostin-binding antibody
|
|
TWI299257B
(en)
*
|
2005-05-16 |
2008-08-01 |
Tung Hai Biotechnology Corp |
γ-POLYGLUTAMIC ACID (γ-PGA, H FORM), γ-POLYGLUTAMATES AND γ-POLYGLUTAMATE HYDROGEL FOR USE AS NUTRITION SUPPLEMENTS IN DIETARY PRODUCTS
|
|
US20060271262A1
(en)
*
|
2005-05-24 |
2006-11-30 |
Mclain Harry P Iii |
Wireless agricultural network
|
|
WO2008018854A2
(en)
*
|
2005-06-06 |
2008-02-14 |
The Rockefeller University |
Bactiophage lysins for bacillus anthracis
|
|
WO2006132788A2
(en)
|
2005-06-06 |
2006-12-14 |
Genentech, Inc. |
Transgenic models for different genes and their use for gene characterization
|
|
WO2006138145A1
(en)
|
2005-06-14 |
2006-12-28 |
Northwestern University |
Nucleic acid functionalized nanoparticles for therapeutic applications
|
|
US7582291B2
(en)
*
|
2005-06-30 |
2009-09-01 |
The Rockefeller University |
Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
|
|
WO2007008943A2
(en)
|
2005-07-08 |
2007-01-18 |
Xencor, Inc. |
Optimized anti-ep-cam antibodies
|
|
RU2423381C2
(ru)
|
2005-07-25 |
2011-07-10 |
Трабьон Фармасьютикалз, Инк. |
Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул
|
|
JP5457671B2
(ja)
*
|
2005-07-28 |
2014-04-02 |
ノバルティス アーゲー |
M−csf特異的モノクローナル抗体およびその使用
|
|
EP2277916A3
(en)
*
|
2005-07-28 |
2011-04-27 |
Novartis AG |
Use of antibody to M-CSF
|
|
US20070092482A1
(en)
*
|
2005-08-04 |
2007-04-26 |
Bossard Mary J |
Conjugates of a G-CSF moiety and a polymer
|
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
|
EP1922410A2
(en)
|
2005-08-15 |
2008-05-21 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
CA2620903A1
(en)
|
2005-08-24 |
2007-03-01 |
The Rockefeller University |
Ply-gbs mutant lysins
|
|
CA2624900A1
(en)
*
|
2005-10-04 |
2007-04-19 |
The Research Foundation Of State University Of New York |
Fibronectin polypeptides and methods of use
|
|
US20090155850A1
(en)
*
|
2005-10-28 |
2009-06-18 |
The Florida International University Board Of Trustees |
Horse:Human Chimeric Antibodies
|
|
AU2006315037C1
(en)
|
2005-11-18 |
2013-05-02 |
Ichnos Sciences SA |
Anti-alpha2 integrin antibodies and their uses
|
|
EP1962584A2
(en)
|
2005-11-21 |
2008-09-03 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
|
ES2618543T3
(es)
*
|
2005-11-23 |
2017-06-21 |
Genentech, Inc. |
Métodos y composiciones relacionados con ensayos de linfocitos B
|
|
US20070213264A1
(en)
|
2005-12-02 |
2007-09-13 |
Mingdong Zhou |
Neuregulin variants and methods of screening and using thereof
|
|
ES2530526T3
(es)
|
2005-12-30 |
2015-03-03 |
Zensun Shanghai Science And Technology Ltd |
Liberación extendida de neurregulina para mejorar la función cardíaca
|
|
WO2007102946A2
(en)
|
2006-01-23 |
2007-09-13 |
Amgen Inc. |
Crystalline polypeptides
|
|
EP2050335A1
(en)
|
2006-02-17 |
2009-04-22 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
TW200745163A
(en)
|
2006-02-17 |
2007-12-16 |
Syntonix Pharmaceuticals Inc |
Peptides that block the binding of IgG to FcRn
|
|
TWI417301B
(zh)
|
2006-02-21 |
2013-12-01 |
Wyeth Corp |
對抗人類介白素-22(il-22)之抗體及其用途
|
|
TW200744634A
(en)
|
2006-02-21 |
2007-12-16 |
Wyeth Corp |
Methods of using antibodies against human IL-22
|
|
JP2009529915A
(ja)
|
2006-03-20 |
2009-08-27 |
ゾーマ テクノロジー リミテッド |
ガストリン物質に対して特異的なヒト抗体および方法
|
|
NZ615012A
(en)
|
2006-03-21 |
2015-11-27 |
Genentech Inc |
Combinatorial therapy involving alpha5beta1 antagonists
|
|
RU2494108C2
(ru)
|
2006-04-07 |
2013-09-27 |
Аерпио Терапетикс, Инк. |
Антитела, которые связывают человеческий белок бета-тирозин фосфатазу (нртрвета), и их использование
|
|
CA2649387A1
(en)
|
2006-04-19 |
2008-03-27 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之c-kit抗體
|
|
US7862812B2
(en)
|
2006-05-31 |
2011-01-04 |
Lpath, Inc. |
Methods for decreasing immune response and treating immune conditions
|
|
NZ573646A
(en)
|
2006-06-12 |
2012-04-27 |
Wyeth Llc |
Single-chain multivalent binding proteins with effector function
|
|
EP2041174A2
(en)
*
|
2006-06-16 |
2009-04-01 |
Lipid Sciences, Inc. |
Novel peptides that promote lipid efflux
|
|
US20080227686A1
(en)
*
|
2006-06-16 |
2008-09-18 |
Lipid Sciences, Inc. |
Novel Peptides that Promote Lipid Efflux
|
|
US20080206142A1
(en)
*
|
2006-06-16 |
2008-08-28 |
Lipid Sciences, Inc. |
Novel Peptides That Promote Lipid Efflux
|
|
US7981425B2
(en)
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
|
US20080096900A1
(en)
|
2006-06-26 |
2008-04-24 |
Amgen Inc. |
Methods for treating atherosclerosis
|
|
CA2659820A1
(en)
*
|
2006-08-04 |
2008-02-14 |
Novartis Ag |
Ephb3-specific antibody and uses thereof
|
|
AR064801A1
(es)
|
2006-08-18 |
2009-04-29 |
Xoma Technology Ltd |
Anticuerpo especifico prlr (receptor de prolactina) y sus usos
|
|
CL2007002567A1
(es)
|
2006-09-08 |
2008-02-01 |
Amgen Inc |
Proteinas aisladas de enlace a activina a humana.
|
|
WO2008039843A2
(en)
*
|
2006-09-26 |
2008-04-03 |
Lipid Sciences, Inc. |
Novel peptides that promote lipid efflux
|
|
CN101516914A
(zh)
|
2006-09-29 |
2009-08-26 |
霍夫曼-拉罗奇有限公司 |
针对ccr5的抗体及其应用
|
|
US7767206B2
(en)
|
2006-10-02 |
2010-08-03 |
Amgen Inc. |
Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto
|
|
EP1914303A1
(en)
*
|
2006-10-09 |
2008-04-23 |
Qiagen GmbH |
Thermus eggertssonii DNA polymerases
|
|
PL2087002T3
(pl)
|
2006-10-27 |
2015-02-27 |
Lpath Inc |
Kompozycje i sposoby do wiązania sfingozyno-1 fosforanu
|
|
US8614103B2
(en)
|
2006-10-27 |
2013-12-24 |
Lpath, Inc. |
Compositions and methods for treating sphingosine-1-phosphate (S1P) related ocular diseases and conditions
|
|
KR20090105913A
(ko)
|
2006-11-02 |
2009-10-07 |
다니엘 제이 카폰 |
이동 부분을 갖는 하이브리드 면역글로불린
|
|
EP2423226A3
(en)
|
2006-11-10 |
2012-05-30 |
Amgen Inc. |
Antibody-based diagnostics and therapeutics
|
|
KR20090087027A
(ko)
|
2006-11-13 |
2009-08-14 |
일라이 릴리 앤드 캄파니 |
염증 질환 및 암의 치료를 위한 티에노피리미디논
|
|
ES2437110T3
(es)
|
2006-11-14 |
2014-01-08 |
Genentech, Inc. |
Moduladores de la regeneración neuronal
|
|
MX2009005466A
(es)
|
2006-11-22 |
2009-08-17 |
Adnexus A Bristol Myers Sqibb |
Terapeuticos dirigidos a base de proteinas manipuladas para receptores de tirosina cinasas, incluyendo receptor de factor de crecimiento tipo insulina-i.
|
|
WO2008070780A1
(en)
|
2006-12-07 |
2008-06-12 |
Novartis Ag |
Antagonist antibodies against ephb3
|
|
CN101199856B
(zh)
*
|
2006-12-15 |
2011-04-20 |
天津协和生物科技发展有限公司 |
一种携氧抗休克药物
|
|
US8183201B2
(en)
*
|
2006-12-26 |
2012-05-22 |
National Cheng Kung University |
Methods of treating αvβ3 integrin-associated diseases by administering polypeptides selective for αvβ3 integrin
|
|
US7943728B2
(en)
*
|
2006-12-26 |
2011-05-17 |
National Cheng Kung University |
Disintegrin variants and their use in treating osteoporosis-induced bone loss and angiogenesis-related diseases
|
|
JP2010517944A
(ja)
*
|
2007-01-26 |
2010-05-27 |
バイオインヴェント インターナショナル アーベー |
Dll4シグナリング阻害薬およびその使用
|
|
TW201307390A
(zh)
|
2007-02-02 |
2013-02-16 |
Amgen Inc |
海帕西啶(hepcidin)、海帕西啶拮抗劑及使用方法
|
|
EP2111228B1
(en)
|
2007-02-02 |
2011-07-20 |
Bristol-Myers Squibb Company |
10Fn3 domain for use in treating diseases associated with inappropriate angiogenesis
|
|
EP2121987B1
(en)
|
2007-02-09 |
2012-06-13 |
Northwestern University |
Particles for detecting intracellular targets
|
|
US8415453B2
(en)
*
|
2007-02-13 |
2013-04-09 |
Academia Sinica |
Lung cancer-targeted peptides and applications thereof
|
|
US8088887B2
(en)
*
|
2007-02-13 |
2012-01-03 |
Academia Sinica |
Peptide-conjugates that bind to VEGF-stimulated or tumor vasculature and methods of treatment
|
|
AU2008218199B2
(en)
|
2007-02-22 |
2013-10-31 |
Genentech, Inc. |
Methods for detecting inflammatory bowel disease
|
|
CN101686939B
(zh)
*
|
2007-04-17 |
2013-03-27 |
巴克斯特国际公司 |
用于肺部投送的核酸微粒
|
|
EP2160464B1
(en)
|
2007-05-30 |
2014-05-21 |
Northwestern University |
Nucleic acid functionalized nanoparticles for therapeutic applications
|
|
ES2585702T3
(es)
|
2007-05-30 |
2016-10-07 |
Lpath, Inc |
Composiciones y métodos para la unión al ácido lisofosfatídico
|
|
US9163091B2
(en)
*
|
2007-05-30 |
2015-10-20 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
|
WO2008157483A2
(en)
*
|
2007-06-14 |
2008-12-24 |
The Research Foundation Of State University Of New York |
Polypeptides and methods of use
|
|
EP2176295B1
(en)
|
2007-07-16 |
2014-11-19 |
Genentech, Inc. |
Humanized anti-cd79b antibodies and immunoconjugates and methods of use
|
|
PE20090943A1
(es)
|
2007-07-16 |
2009-08-05 |
Genentech Inc |
Anticuerpos anti-cd79b e inmunoconjugados
|
|
HRP20140315T1
(hr)
|
2007-07-26 |
2014-05-09 |
Amgen Inc. |
Modificirani enzimi lecitin-kolesterol aciltransferaze
|
|
CN101361968B
(zh)
|
2007-08-06 |
2011-08-03 |
健能隆医药技术(上海)有限公司 |
白介素-22在治疗脂肪肝中的应用
|
|
TW200911289A
(en)
*
|
2007-08-09 |
2009-03-16 |
Syntonix Pharmaceuticals Inc |
Immunomodulatory peptides
|
|
EP2615114B1
(en)
|
2007-08-23 |
2022-04-06 |
Amgen Inc. |
Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
|
|
JOP20080381B1
(ar)
|
2007-08-23 |
2023-03-28 |
Amgen Inc |
بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
|
|
MX338397B
(es)
|
2007-08-29 |
2016-04-15 |
Sanofi Aventis |
Anticuerpos anti - cxcr5 humanizados, derivados de los mismos y su uso.
|
|
US7982016B2
(en)
|
2007-09-10 |
2011-07-19 |
Amgen Inc. |
Antigen binding proteins capable of binding thymic stromal lymphopoietin
|
|
US20090156488A1
(en)
*
|
2007-09-12 |
2009-06-18 |
Zensun (Shanghai) Science & Technology Limited |
Use of neuregulin for organ preservation
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
US8361465B2
(en)
*
|
2007-10-26 |
2013-01-29 |
Lpath, Inc. |
Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
|
|
EP2612867A1
(en)
|
2007-11-01 |
2013-07-10 |
Perseid Therapeutics LLC |
Immunosuppressive polypeptides and nucleic acids
|
|
US8541543B2
(en)
*
|
2007-11-20 |
2013-09-24 |
Academia Sinica |
Peptides specific for hepatocellular carcinoma cells and applications thereof
|
|
RU2559782C2
(ru)
|
2007-12-17 |
2015-08-10 |
Марфл Аб |
Набор для детекции спор, происходящих из микобактерий
|
|
EP2235058A2
(en)
|
2007-12-21 |
2010-10-06 |
Amgen, Inc |
Anti-amyloid antibodies and uses thereof
|
|
HRP20150279T1
(hr)
|
2007-12-26 |
2015-05-08 |
Xencor, Inc. |
Fc inaäśice s promijenjenim vezanjem na fcrn
|
|
WO2009094551A1
(en)
|
2008-01-25 |
2009-07-30 |
Amgen Inc. |
Ferroportin antibodies and methods of use
|
|
KR101607346B1
(ko)
|
2008-01-31 |
2016-03-29 |
제넨테크, 인크. |
항-cd79b 항체 및 면역접합체 및 사용 방법
|
|
EP2238170B1
(en)
|
2008-01-31 |
2016-11-23 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Antibodies against human cd39 and use thereof for inhibiting t regulatory cells activity
|
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
WO2009126725A1
(en)
*
|
2008-04-09 |
2009-10-15 |
The Regents Of The University Of Michigan |
Method of modulating neovascularization
|
|
SG10202112838YA
(en)
|
2008-04-09 |
2021-12-30 |
Genentech Inc |
Novel compositions and methods for the treatment of immune related diseases
|
|
RU2531754C2
(ru)
|
2008-04-11 |
2014-10-27 |
ЭМЕРДЖЕНТ ПРОДАКТ ДИВЕЛОПМЕНТ СИЭТЛ,ЭлЭлСи,US |
Связывающееся с cd37 иммунотерапевтическое средство и его комбинация с бифункциональным химиотерапевтическим средством
|
|
US8921315B1
(en)
|
2008-04-24 |
2014-12-30 |
Neumedicines, Inc. |
Method of increasing survival of a human subject having exposure to an acute exposure to non-therapeutic whole body ionization by administering a therapeutically effective dose of IL-12
|
|
US9315577B2
(en)
|
2008-05-01 |
2016-04-19 |
Amgen Inc. |
Anti-hepcidin antibodies and methods of use
|
|
US7833530B2
(en)
|
2008-05-15 |
2010-11-16 |
Selexys Pharmaceuticals Corporation |
Methods of inhibiting the PSGL-1-mediated adhesion and chemokine-mediated migration with PSGL-1-specific antibodies
|
|
US8093018B2
(en)
|
2008-05-20 |
2012-01-10 |
Otsuka Pharmaceutical Co., Ltd. |
Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same
|
|
WO2009142773A2
(en)
|
2008-05-22 |
2009-11-26 |
Bristol-Myers Squibb Company |
Multivalent fibronectin based scaffold domain proteins
|
|
US8034770B2
(en)
|
2008-06-04 |
2011-10-11 |
Amgen Inc. |
FGF21 polypeptides comprising two or more mutations
|
|
JP2011526916A
(ja)
*
|
2008-06-30 |
2011-10-20 |
ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
全身性紅斑性狼瘡を同定および処置するための診断標的および治療標的としてのリソソームホスホリパーゼa2(lpla2)活性
|
|
WO2010014909A1
(en)
*
|
2008-08-01 |
2010-02-04 |
Syntonix Pharmaceuticals, Inc. |
Immunomodulatory peptides
|
|
NZ591488A
(en)
|
2008-09-07 |
2012-11-30 |
Glyconex Inc |
Anti-extended type i glycosphingolipid antibody, derivatives thereof and use
|
|
NO2344540T3
(enExample)
|
2008-10-02 |
2018-04-28 |
|
|
|
WO2010040766A1
(en)
|
2008-10-07 |
2010-04-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Neutralizing antibodies and fragments thereof directed against platelet factor-4 variant 1 (pf4v1)
|
|
CA2739615C
(en)
|
2008-10-10 |
2017-12-05 |
Amgen Inc. |
Fgf21 mutants comprising polyethylene glycol and uses thereof
|
|
JP5851838B2
(ja)
|
2008-10-22 |
2016-02-03 |
ジェネンテック, インコーポレイテッド |
軸索変性の調節
|
|
US8871202B2
(en)
|
2008-10-24 |
2014-10-28 |
Lpath, Inc. |
Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
|
|
WO2010052556A1
(en)
*
|
2008-11-06 |
2010-05-14 |
Glenmark Pharmaceuticals S.A. |
Treatment with anti-alpha2 integrin antibodies
|
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
KR20160091440A
(ko)
|
2008-11-13 |
2016-08-02 |
길리아드 칼리스토가 엘엘씨 |
혈액 종양에 대한 요법
|
|
EP2365803B1
(en)
|
2008-11-24 |
2017-11-01 |
Northwestern University |
Polyvalent rna-nanoparticle compositions
|
|
KR101792032B1
(ko)
|
2008-12-19 |
2017-11-02 |
백스터 인터내셔널 인코포레이티드 |
Tfpi 억제제 및 사용 방법
|
|
US20100233270A1
(en)
|
2009-01-08 |
2010-09-16 |
Northwestern University |
Delivery of Oligonucleotide-Functionalized Nanoparticles
|
|
US20100294952A1
(en)
*
|
2009-01-15 |
2010-11-25 |
Northwestern University |
Controlled agent release and sequestration
|
|
EP3002296B1
(en)
|
2009-03-17 |
2020-04-29 |
Université d'Aix-Marseille |
Btla antibodies and uses thereof
|
|
CA2755336C
(en)
|
2009-03-20 |
2015-07-14 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
|
BRPI1012333A2
(pt)
|
2009-03-24 |
2016-03-29 |
Gilead Calistoga Llc |
atropisômeros de derivados de 2-purinil-3-tolil-quinazolinonas e métodos de uso
|
|
NZ594343A
(en)
|
2009-03-25 |
2013-10-25 |
Genentech Inc |
Novel anti-alpha5beta1 antibodies and uses thereof
|
|
RU2587621C2
(ru)
|
2009-04-01 |
2016-06-20 |
Дженентек, Инк. |
АНТИТЕЛА К FcRH5, ИХ ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
|
MA33248B1
(fr)
|
2009-04-01 |
2012-05-02 |
Genentech Inc |
Traitement de troubles résistant à l'insuline
|
|
WO2010112034A2
(en)
|
2009-04-02 |
2010-10-07 |
Aarhus Universitet |
Compositions and methods for treatment and diagnosis of synucleinopathies
|
|
US8067201B2
(en)
*
|
2009-04-17 |
2011-11-29 |
Bristol-Myers Squibb Company |
Methods for protein refolding
|
|
AP2011005956A0
(en)
*
|
2009-04-20 |
2011-10-31 |
Gilead Calistoga Llc |
Methods of treatment for solid tumors.
|
|
EP2248903A1
(en)
|
2009-04-29 |
2010-11-10 |
Universitat Autònoma De Barcelona |
Methods and reagents for efficient and targeted gene transfer to monocytes and macrophages
|
|
WO2010129503A1
(en)
|
2009-05-05 |
2010-11-11 |
Amgen Inc. |
Fgf21 mutants and uses thereof
|
|
WO2010129600A2
(en)
|
2009-05-05 |
2010-11-11 |
Amgen Inc. |
Fgf21 mutants and uses thereof
|
|
TW201102086A
(en)
|
2009-06-04 |
2011-01-16 |
Hoffmann La Roche |
Antibodies against human CCN1 and uses thereof
|
|
AU2010260145B2
(en)
|
2009-06-15 |
2015-08-20 |
Valerion Therapeutics, Llc |
Methods and compositions for treatment of Myotubular Myopathy using chimeric polypeptides comprising myotubularin 1 (MTM1) polypeptides
|
|
MX2011013903A
(es)
|
2009-06-17 |
2012-05-08 |
Amgen Inc |
Polipeptidos quimericos y usos de los mismos.
|
|
KR20120097481A
(ko)
*
|
2009-07-20 |
2012-09-04 |
내셔날 쳉쿵 유니버시티 |
사람 혈청 알부민(HSA)의 변이체와 컨쥬게이션된 αvβ3 인테그린에 대해 선택적인 폴리펩타이드 및 이의 약제학적 용도
|
|
CA2768843A1
(en)
|
2009-07-21 |
2011-01-27 |
Gilead Calistoga Llc |
Treatment of liver disorders with pi3k inhibitors
|
|
NZ597531A
(en)
|
2009-07-31 |
2014-05-30 |
Genentech Inc |
Inhibition of tumor metastasis using bv8- or g-csf-antagonists
|
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
EP2480888B1
(en)
|
2009-09-25 |
2016-11-30 |
XOMA Technology Ltd. |
Screening methods
|
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
|
WO2011045704A1
(en)
|
2009-10-12 |
2011-04-21 |
Pfizer Inc. |
Cancer treatment
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
KR101952453B1
(ko)
*
|
2009-10-15 |
2019-02-26 |
제넨테크, 인크. |
수용체 특이성이 변경된 키메라 섬유모세포 성장 인자
|
|
WO2011049625A1
(en)
|
2009-10-20 |
2011-04-28 |
Mansour Samadpour |
Method for aflatoxin screening of products
|
|
JP5819308B2
(ja)
|
2009-10-22 |
2015-11-24 |
ジェネンテック, インコーポレイテッド |
マクロファージ刺激タンパク質のヘプシン活性化を調節するための方法及び組成物
|
|
EP3011970A3
(en)
|
2009-10-22 |
2016-06-08 |
F. Hoffmann-La Roche AG |
Modulation of axon degeneration
|
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
|
WO2011056494A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor-like kinase-1 antagonist and vegfr3 antagonist combinations
|
|
CA2779099C
(en)
|
2009-10-30 |
2021-08-10 |
Northwestern University |
Templated nanoconjugates
|
|
NZ599830A
(en)
|
2009-11-05 |
2014-08-29 |
Rhizen Pharmaceuticals Sa |
Novel kinase modulators
|
|
US20110110942A1
(en)
|
2009-11-12 |
2011-05-12 |
Genentech, Inc. |
Method of promoting dendritic spine density
|
|
US9260517B2
(en)
|
2009-11-17 |
2016-02-16 |
Musc Foundation For Research Development |
Human monoclonal antibodies to human nucleolin
|
|
US20120231006A1
(en)
|
2009-11-20 |
2012-09-13 |
Amgen Inc. |
Anti-orai1 antigen binding proteins and uses thereof
|
|
WO2011066511A1
(en)
|
2009-11-30 |
2011-06-03 |
The U.S.A., As Represented By The Secretary Department Of Health And Human Services |
Synthetic apoa-1 mimetic amphipathic peptides and methods of use thereof
|
|
PH12012500982A1
(en)
|
2009-11-30 |
2019-07-10 |
Genentech Inc |
Antibodies for treating and diagnosing tumors expressing slc34a2 (tat211=seqid2)
|
|
EP2679234A3
(en)
*
|
2009-12-02 |
2014-04-23 |
Amgen Inc. |
Binding proteins that bind to human FGFR1C, human beta-klotho and both human FGFR1C and human beta-klotho
|
|
UA109888C2
(uk)
*
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
|
US20120288507A1
(en)
|
2009-12-18 |
2012-11-15 |
Amgen Inc. |
Wise binding agents and epitopes
|
|
RS54795B1
(sr)
|
2009-12-22 |
2016-10-31 |
Roche Glycart Ag |
Anti-her3 antitela i njihova korišćenja
|
|
NZ600544A
(en)
|
2009-12-23 |
2014-06-27 |
Univ Nat Cheng Kung |
Compositions and methods for the treatment of angiogenesis-related eye diseases
|
|
WO2011079308A2
(en)
|
2009-12-23 |
2011-06-30 |
Emergent Product Development Seattle, Llc |
Compositions comprising tnf-alpha and il-6 antagonists and methods of use thereof
|
|
CA2785907A1
(en)
|
2009-12-29 |
2011-07-28 |
Emergent Product Development Seattle, Llc |
Ron binding constructs and methods of use thereof
|
|
WO2011097527A2
(en)
|
2010-02-04 |
2011-08-11 |
Xencor, Inc. |
Immunoprotection of therapeutic moieties using enhanced fc regions
|
|
US20110189178A1
(en)
*
|
2010-02-04 |
2011-08-04 |
Xencor, Inc. |
Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions
|
|
KR20130020765A
(ko)
|
2010-02-16 |
2013-02-28 |
메디뮨 엘엘씨 |
Hsa-관련 조성물 및 사용방법
|
|
CA2790866C
(en)
|
2010-02-23 |
2019-02-12 |
Sanofi |
Anti-alpha2 integrin antibodies and their uses
|
|
MA34057B1
(fr)
|
2010-02-23 |
2013-03-05 |
Genentech Inc |
Compositions et methodes pour le diagnostic et le traitement d'une tumeur
|
|
CN102859364A
(zh)
|
2010-02-25 |
2013-01-02 |
桑格特公司 |
通过减少反应物比例制备聚乙二醇-血红蛋白缀合物的方法
|
|
US20110212088A1
(en)
*
|
2010-02-26 |
2011-09-01 |
Sabbadini Roger A |
Anti-paf antibodies
|
|
CN106432474A
(zh)
|
2010-03-12 |
2017-02-22 |
艾伯维生物医疗股份有限公司 |
Ctla4蛋白和其用途
|
|
DK2547355T3
(en)
|
2010-03-19 |
2017-03-20 |
Baxalta GmbH |
TFPI INHIBITORS AND METHODS OF USE
|
|
HUE049849T2
(hu)
|
2010-03-31 |
2020-10-28 |
Boehringer Ingelheim Int |
Anti-CD40 antitestek
|
|
DK2552443T3
(da)
|
2010-04-01 |
2021-09-27 |
Oncorena Ab |
Forbedret behandling af nyrecellekarcinom
|
|
CA2796055A1
(en)
|
2010-04-15 |
2011-10-20 |
Amgen Inc. |
Human fgf receptor and .beta.-klotho binding proteins
|
|
SG185027A1
(en)
|
2010-05-03 |
2012-11-29 |
Genentech Inc |
Compositions and methods for the diagnosis and treatment of tumor
|
|
NZ604306A
(en)
|
2010-05-17 |
2015-02-27 |
Incozen Therapeutics Pvt Ltd |
Novel 3,5-disubstitued-3h-imidazo[4,5-b]pyridine and 3,5- disubstitued -3h-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of protein kinases
|
|
US9878012B2
(en)
|
2010-05-18 |
2018-01-30 |
Neumedicines, Inc. |
IL-12 formulations for enhancing hematopoiesis
|
|
JP6023703B2
(ja)
|
2010-05-26 |
2016-11-09 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
改善された安定性を有するフィブロネクチンをベースとする足場タンパク質
|
|
CA2802994A1
(en)
|
2010-06-17 |
2011-12-22 |
The United States Of America As Represented By The Secretary, National I Nstitutes Of Health |
Compositions and methods for treating inflammatory conditions
|
|
WO2012007495A1
(en)
|
2010-07-15 |
2012-01-19 |
F. Hoffmann-La Roche Ag |
Antibodies specifically binding to human tslpr and methods of use
|
|
US9040671B2
(en)
|
2010-07-23 |
2015-05-26 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods for cancer management targeting Co-029
|
|
AU2011283694B2
(en)
|
2010-07-29 |
2017-04-13 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
JP2013537416A
(ja)
|
2010-08-13 |
2013-10-03 |
メディミューン リミテッド |
変異型Fc領域を含むモノマーポリペプチド及び使用方法
|
|
CN105198981B
(zh)
|
2010-08-20 |
2019-07-16 |
惠氏有限责任公司 |
经设计的成骨蛋白
|
|
US9688735B2
(en)
|
2010-08-20 |
2017-06-27 |
Wyeth Llc |
Designer osteogenic proteins
|
|
CN102380091A
(zh)
|
2010-08-31 |
2012-03-21 |
健能隆医药技术(上海)有限公司 |
白介素-22在治疗病毒性肝炎中的应用
|
|
MX360946B
(es)
|
2010-09-22 |
2018-10-29 |
Amgen Inc Star |
Inmunoglobulinas portadoras y usos de las mismas.
|
|
EP3828205A1
(en)
|
2010-10-01 |
2021-06-02 |
Oxford BioTherapeutics Ltd |
Anti-ror1 antibodies
|
|
US9445990B2
(en)
|
2010-10-06 |
2016-09-20 |
Medtronic, Inc. |
TNF inhibitor formulation for use in implantable infusion devices
|
|
US20120201821A1
(en)
|
2010-10-25 |
2012-08-09 |
Gonzalez Jr Lino |
Treatment of Gastrointestinal Inflammation and Psoriasis and Asthma
|
|
MX2019000046A
(es)
|
2010-11-04 |
2023-10-05 |
Boehringer Ingelheim Int |
Anticuerpos anti-il-23.
|
|
US9023791B2
(en)
|
2010-11-19 |
2015-05-05 |
Novartis Ag |
Fibroblast growth factor 21 mutations
|
|
WO2012080769A1
(en)
|
2010-12-15 |
2012-06-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-cd277 antibodies and uses thereof
|
|
EP2654781B1
(en)
|
2010-12-21 |
2018-01-24 |
Selexys Pharmaceuticals Corporation |
Anti-p-selectin antibodies and methods of their use and identification
|
|
EP2654789B1
(en)
|
2010-12-22 |
2018-05-30 |
Orega Biotech |
Antibodies against human cd39 and use thereof
|
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
|
SG10201600531TA
(en)
|
2011-01-24 |
2016-02-26 |
Univ Singapore |
Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
|
|
WO2012101125A1
(en)
|
2011-01-24 |
2012-08-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Specific antibodies against human cxcl4 and uses thereof
|
|
EP2678358B1
(en)
|
2011-02-23 |
2015-07-22 |
F.Hoffmann-La Roche Ag |
Antibodies against human il33r and uses thereof
|
|
TWI719112B
(zh)
|
2011-03-16 |
2021-02-21 |
賽諾菲公司 |
雙重v區類抗體蛋白質之用途
|
|
EP3147297B1
(en)
|
2011-03-31 |
2018-12-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies directed against icos and uses thereof
|
|
US8628773B2
(en)
|
2011-04-07 |
2014-01-14 |
Amgen Inc. |
Antigen binding proteins
|
|
DK2699598T3
(en)
|
2011-04-19 |
2019-04-23 |
Pfizer |
COMBINATIONS OF ANTI-4-1BB ANTIBODIES AND ADCC-INducing ANTIBODIES FOR TREATMENT OF CANCER
|
|
PH12013502240B1
(en)
|
2011-05-04 |
2018-06-27 |
Rhizen Pharmaceuticals Sa |
Novel compounds as modulators of protein kinase
|
|
JOP20200043A1
(ar)
|
2011-05-10 |
2017-06-16 |
Amgen Inc |
طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
|
|
CN108892709A
(zh)
|
2011-05-18 |
2018-11-27 |
欧莫德里斯制药公司 |
改良的肽药物
|
|
DK2710031T3
(en)
|
2011-05-18 |
2018-01-02 |
Mederis Diabetes Llc |
IMPROVED PEPTID MEDICINALS FOR INSULIN RESISTANCE
|
|
JP2014516960A
(ja)
|
2011-05-19 |
2014-07-17 |
インサーム(インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル) |
抗ヒトher3抗体及びその使用
|
|
CN103732623B
(zh)
|
2011-06-03 |
2017-09-29 |
佐马技术有限公司 |
对TGF‑β具有特异性的抗体
|
|
DK3412305T3
(da)
|
2011-06-10 |
2021-03-01 |
Baxalta GmbH |
Behandling af koagulationssygdom ved administration af rekombinant vwf
|
|
WO2012174056A1
(en)
|
2011-06-13 |
2012-12-20 |
Neumedicines, Inc. |
Mitigation of cutaneous injury with il-12
|
|
WO2012178063A1
(en)
|
2011-06-23 |
2012-12-27 |
The Regents Of The University Of Michigan |
Compound and method for modulating opioid receptor activity
|
|
EP2543679A1
(en)
|
2011-07-08 |
2013-01-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the treatment and prevention of thrombosis
|
|
EP2543678A1
(en)
|
2011-07-08 |
2013-01-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the treatment and prevention of thrombosis
|
|
EP2543677A1
(en)
|
2011-07-08 |
2013-01-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the treatment and prevention of thrombosis
|
|
WO2013012855A1
(en)
|
2011-07-18 |
2013-01-24 |
Amgen Inc. |
Apelin antigen-binding proteins and uses thereof
|
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
|
WO2013022855A1
(en)
|
2011-08-05 |
2013-02-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points and immunofiltering
|
|
WO2013025479A1
(en)
|
2011-08-16 |
2013-02-21 |
Emory University |
Jaml specific binding agents, antibodies, and uses related thereto
|
|
KR20140068877A
(ko)
|
2011-08-17 |
2014-06-09 |
제넨테크, 인크. |
불응성 종양에서의 혈관신생의 억제
|
|
MX2014002260A
(es)
|
2011-08-31 |
2014-08-18 |
Amgen Inc |
Factor de crecimiento de fibroblasto 21 para usar en el tratamiento de diabetes tipo 1.
|
|
AU2012308302A1
(en)
|
2011-09-14 |
2014-03-20 |
Northwestern University |
Nanoconjugates able to cross the blood-brain barrier
|
|
MX353958B
(es)
|
2011-09-22 |
2018-02-07 |
Amgen Inc |
Proteinas de union al antigeno cd27l.
|
|
UY34347A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de función dual para tratar trastornos metabólicos
|
|
AU2012323287B2
(en)
|
2011-10-10 |
2018-02-01 |
Xencor, Inc. |
A method for purifying antibodies
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
WO2013053076A1
(en)
|
2011-10-10 |
2013-04-18 |
Zensun (Shanghai)Science & Technology Limited |
Compositions and methods for treating heart failure
|
|
WO2013056240A1
(en)
|
2011-10-13 |
2013-04-18 |
Aerpio Therapeutics, Inc. |
Methods for treating vascular leak syndrome and cancer
|
|
BR112014008759A8
(pt)
|
2011-10-13 |
2017-09-12 |
Aerpio Therapeutics Inc |
Tratamento de doença ocular
|
|
JP2015504038A
(ja)
|
2011-10-31 |
2015-02-05 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
低減した免疫原性を有するフィブロネクチン結合ドメイン
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
|
SI3536710T1
(sl)
|
2011-11-16 |
2026-04-30 |
Boehringer Ingelheim International Gmbh |
Protitelesa proti IL-36R
|
|
BR112014012590A8
(pt)
|
2011-11-23 |
2017-12-19 |
Igenica Inc |
Anticorpos anti-cd98 e métodos de uso dos mesmos
|
|
HK1202433A1
(en)
|
2011-12-16 |
2015-10-02 |
Kalos Therapeutics, Inc. |
Methods and uses of anp (atrial natriuretic peptide), bnp (brain natriuretic peptide) and cnp (c-type natriuretic peptide)-related peptides and derivatives thereof for treatment of retinal disorders and diseases
|
|
WO2013096948A1
(en)
|
2011-12-23 |
2013-06-27 |
Lydon Nicholas B |
Immunoglobulins and variants directed against pathogenic microbes
|
|
US9988439B2
(en)
|
2011-12-23 |
2018-06-05 |
Nicholas B. Lydon |
Immunoglobulins and variants directed against pathogenic microbes
|
|
JP2015505326A
(ja)
|
2012-01-18 |
2015-02-19 |
ニューメディシンズ,インコーポレーテッド |
放射線防護及び放射線誘発性毒性緩和のためのil−12
|
|
KR101855242B1
(ko)
|
2012-01-26 |
2018-05-09 |
크리스토퍼 제이. 소레스 |
펩타이드 호르몬의 칼시토닌 cgrp 패밀리의 펩타이드 길항제 및 그의 용도
|
|
NZ629684A
(en)
|
2012-03-05 |
2016-10-28 |
Gilead Calistoga Llc |
Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
|
|
CA2867444C
(en)
|
2012-03-16 |
2021-04-13 |
University Health Network |
Compositions containing soluble toso protein and uses thereof
|
|
BR112014022435B1
(pt)
|
2012-03-21 |
2023-02-14 |
Takeda Pharmaceutical Company Limited |
Inibidores de tfpi e métodos de uso
|
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
|
CA2868883C
(en)
|
2012-03-30 |
2022-10-04 |
Sorrento Therapeutics Inc. |
Fully human antibodies that bind to vegfr2
|
|
CN107082779A
(zh)
|
2012-03-30 |
2017-08-22 |
理森制药股份公司 |
作为c‑met 蛋白激酶调节剂的新化合物
|
|
WO2013151649A1
(en)
|
2012-04-04 |
2013-10-10 |
Sialix Inc |
Glycan-interacting compounds
|
|
WO2013155346A1
(en)
|
2012-04-11 |
2013-10-17 |
The Regents Of The University Of California |
Diagnostic tools for response to 6-thiopurine therapy
|
|
EA039663B1
(ru)
|
2012-05-03 |
2022-02-24 |
Амген Инк. |
Применение антитела против pcsk9 для снижения сывороточного холестерина лпнп и лечения связанных с холестерином расстройств
|
|
PL3326649T3
(pl)
|
2012-05-03 |
2022-04-25 |
Boehringer Ingelheim International Gmbh |
Przeciwciała anty-il-23p19
|
|
US9441039B2
(en)
|
2012-05-07 |
2016-09-13 |
Amgen Inc. |
Anti-erythropoietin antibodies
|
|
WO2013172954A1
(en)
|
2012-05-17 |
2013-11-21 |
Ra Pharmaceuticals, Inc |
Peptide and peptidomimetic inhibitors
|
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
|
KR20220084444A
(ko)
|
2012-05-31 |
2022-06-21 |
소렌토 쎄라퓨틱스, 인코포레이티드 |
Pd-l1에 결합하는 항원 결합 단백질
|
|
NZ703724A
(en)
|
2012-06-11 |
2017-06-30 |
Amgen Inc |
Dual receptor antagonistic antigen-binding proteins and uses thereof
|
|
CN105050618B
(zh)
|
2012-06-21 |
2018-11-16 |
索伦托治疗有限公司 |
与c-Met结合的抗原结合蛋白
|
|
WO2013192596A2
(en)
|
2012-06-22 |
2013-12-27 |
Sorrento Therapeutics Inc. |
Antigen binding proteins that bind ccr2
|
|
WO2014001368A1
(en)
|
2012-06-25 |
2014-01-03 |
Orega Biotech |
Il-17 antagonist antibodies
|
|
EP3431497B1
(en)
|
2012-06-27 |
2022-07-27 |
The Trustees of Princeton University |
Split inteins, conjugates and uses thereof
|
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
|
US9873739B2
(en)
|
2012-08-01 |
2018-01-23 |
Ikaika Therapeutics, Llc |
Mitigating tissue damage and fibrosis via latent transforming growth factor beta binding protein (LTBP4)
|
|
EP2879710B1
(en)
|
2012-08-03 |
2019-11-13 |
Dana-Farber Cancer Institute, Inc. |
Medical uses of agents that modulate immune cell activation and corresponding screening methods
|
|
US9695247B2
(en)
|
2012-09-03 |
2017-07-04 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Antibodies directed against ICOS for treating graft-versus-host disease
|
|
TWI595007B
(zh)
|
2012-09-10 |
2017-08-11 |
Neotope Biosciences Ltd |
抗mcam抗體及相關使用方法
|
|
EP3738605A1
(en)
|
2012-09-10 |
2020-11-18 |
Xencor, Inc. |
Methods of treating neurological diseases
|
|
CA2887129A1
(en)
|
2012-10-09 |
2014-04-17 |
Igenica, Inc. |
Anti-c16orf54 antibodies and methods of use thereof
|
|
MX360816B
(es)
|
2012-11-20 |
2018-11-15 |
Mederis Diabetes Llc |
Productos farmacéuticos peptídicos mejorados para la resistencia a la insulina.
|
|
ES2906975T3
(es)
|
2012-11-20 |
2022-04-21 |
Eumederis Pharmaceuticals Inc |
Productos farmacéuticos de péptidos mejorados
|
|
DK3199552T3
(da)
|
2012-11-20 |
2020-03-30 |
Sanofi Sa |
Anti-ceacam5-antistoffer og anvendelser heraf
|
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
|
HK1210713A1
(en)
|
2012-12-27 |
2016-05-06 |
Sanofi |
Anti-lamp1 antibodies and antibody drug conjugates, and uses thereof
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
KR102211837B1
(ko)
|
2013-01-14 |
2021-02-03 |
젠코어 인코포레이티드 |
신규한 이형이량체 단백질
|
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
WO2014113510A1
(en)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
EP2948478B1
(en)
|
2013-01-25 |
2019-04-03 |
Amgen Inc. |
Antibodies targeting cdh19 for melanoma
|
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
|
EP2951206A2
(en)
|
2013-02-01 |
2015-12-09 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold proteins
|
|
AU2014212014A1
(en)
|
2013-02-01 |
2015-08-27 |
Amgen Inc. |
Administration of an anti-activin-A compound to a subject
|
|
US9580486B2
(en)
|
2013-03-14 |
2017-02-28 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
|
EP2970486B1
(en)
|
2013-03-15 |
2018-05-16 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
US9260527B2
(en)
|
2013-03-15 |
2016-02-16 |
Sdix, Llc |
Anti-human CXCR4 antibodies and methods of making same
|
|
PT3611180T
(pt)
|
2013-03-15 |
2022-03-15 |
Biomolecular Holdings Llc |
Imunoglobulina híbrida que contém uma ligação não peptídica
|
|
PL2970449T3
(pl)
|
2013-03-15 |
2020-04-30 |
Amgen Research (Munich) Gmbh |
Jednołańcuchowe cząsteczki wiążące zawierające N-końcowy ABP
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
|
JP6594855B2
(ja)
|
2013-03-15 |
2019-10-23 |
ゼンコア インコーポレイテッド |
ヘテロ二量体タンパク質
|
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
WO2014152006A2
(en)
|
2013-03-15 |
2014-09-25 |
Intrinsic Lifesciences, Llc |
Anti-hepcidin antibodies and uses thereof
|
|
WO2014145016A2
(en)
|
2013-03-15 |
2014-09-18 |
Genentech, Inc. |
Il-22 polypeptides and il-22 fc fusion proteins and methods of use
|
|
EP2970446A1
(en)
|
2013-03-15 |
2016-01-20 |
Amgen Research (Munich) GmbH |
Antibody constructs for influenza m2 and cd3
|
|
RS61778B1
(sr)
|
2013-05-06 |
2021-06-30 |
Scholar Rock Inc |
Kompozicije i postupci za modulaciju faktora rasta
|
|
WO2014183885A1
(en)
|
2013-05-17 |
2014-11-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antagonist of the btla/hvem interaction for use in therapy
|
|
HUE056580T2
(hu)
|
2013-05-30 |
2022-02-28 |
Kiniksa Pharmaceuticals Ltd |
Onkosztatin-M-receptor antigénjét kötõ fehérjék
|
|
WO2014194302A2
(en)
|
2013-05-31 |
2014-12-04 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-1
|
|
CA2916259C
(en)
|
2013-06-28 |
2024-02-20 |
Amgen Inc. |
Methods for treating homozygous familial hypercholesterolemia
|
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
|
WO2015048312A1
(en)
|
2013-09-26 |
2015-04-02 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
CA2924386C
(en)
|
2013-10-04 |
2021-07-20 |
F. Hoffmann-La Roche Ag |
Antibodies specifically binding to her3
|
|
CN105745224B
(zh)
|
2013-10-11 |
2019-11-05 |
牛津生物疗法有限公司 |
用于治疗癌症的针对ly75的偶联抗体
|
|
WO2015057583A1
(en)
|
2013-10-14 |
2015-04-23 |
The United States Of America, As Represented By The Secretary |
Treatment of chronic kidney disease with sahps
|
|
EP3057605A1
(en)
|
2013-10-18 |
2016-08-24 |
Novartis AG |
Methods of treating diabetes and related disorders
|
|
EP3063317B1
(en)
|
2013-10-28 |
2020-06-03 |
DOTS Technology Corp. |
Allergen detection
|
|
HRP20192080T1
(hr)
|
2013-10-31 |
2020-02-07 |
Resolve Therapeutics, Llc |
Terapeutske fuzije nukleaza-albumine i postupci
|
|
CN104623637A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
Il-22二聚体在制备静脉注射药物中的应用
|
|
NZ736970A
(en)
|
2013-12-20 |
2018-11-30 |
Gilead Calistoga Llc |
Process methods for phosphatidylinositol 3-kinase inhibitors
|
|
WO2015095605A1
(en)
|
2013-12-20 |
2015-06-25 |
Gilead Calistoga Llc |
Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
|
|
AU2015204446A1
(en)
|
2014-01-13 |
2016-07-14 |
Valerion Therapeutics, Llc |
Internalizing moieties
|
|
PE20170256A1
(es)
|
2014-01-24 |
2017-04-22 |
Ngm Biopharmaceuticals Inc |
Proteinas de union y sus metodos de uso
|
|
EA033604B1
(ru)
|
2014-01-31 |
2019-11-08 |
Boehringer Ingelheim Int |
Молекула анти-baff антитела, фармацевтическая композиция, содержащая эту молекулу, способы ее применения и кодирующий ее изолированный полинуклеотид
|
|
WO2015127134A2
(en)
|
2014-02-20 |
2015-08-27 |
Allergan, Inc. |
Complement component c5 antibodies
|
|
CN110724691A
(zh)
|
2014-02-27 |
2020-01-24 |
阿勒根公司 |
补体因子Bb抗体
|
|
AU2015225867B2
(en)
|
2014-03-07 |
2020-02-06 |
University Health Network |
Methods and compositions for modifying the immune response
|
|
KR102587838B1
(ko)
|
2014-03-14 |
2023-10-12 |
바이오몰레큘러 홀딩스 엘엘씨 |
비-펩티드 결합을 함유하는 하이브리드 면역글로불린
|
|
EP3699195A3
(en)
|
2014-03-28 |
2020-11-04 |
Xencor, Inc. |
Bispecific antibodies that bind to cd38 and cd3
|
|
US10544231B2
(en)
|
2014-04-16 |
2020-01-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the prevention or the treatment of bleeding episodes
|
|
FR3020063A1
(fr)
|
2014-04-16 |
2015-10-23 |
Gamamabs Pharma |
Anticorps humain anti-her4
|
|
PT3155017T
(pt)
|
2014-05-28 |
2024-05-14 |
Mederis Diabetes Llc |
Farmacêuticos peptídicos melhorados para resistência à insulina
|
|
EP3613433B1
(en)
|
2014-05-30 |
2022-01-05 |
Shanghai Henlius Biotech, Inc. |
Anti-epidermal growth factor receptor (egfr) antibodies
|
|
EP3973994A1
(en)
|
2014-06-12 |
2022-03-30 |
RA Pharmaceuticals, Inc. |
Modulation of complement activity
|
|
MA40059A
(fr)
|
2014-06-13 |
2015-12-17 |
Gilead Sciences Inc |
Inhibiteurs de la phosphatidylinositol 3-kinase
|
|
JP6655074B2
(ja)
|
2014-06-20 |
2020-02-26 |
ジェネンテック, インコーポレイテッド |
シャガシンに基づく足場組成物、方法及び使用
|
|
MX384418B
(es)
|
2014-07-31 |
2025-03-14 |
Amgen Res Munich Gmbh |
Constructo de anticuerpo de cadena individual biespecífico con distribución mejorada de tejido.
|
|
EP3174901B1
(en)
|
2014-07-31 |
2019-06-26 |
Amgen Research (Munich) GmbH |
Optimized cross-species specific bispecific single chain antibody constructs
|
|
UY36245A
(es)
|
2014-07-31 |
2016-01-29 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
|
EA201790437A1
(ru)
|
2014-08-22 |
2017-08-31 |
Сорренто Терапьютикс, Инк. |
Антигенсвязывающие белки, связывающиеся с cxcr3
|
|
MX382490B
(es)
|
2014-08-27 |
2025-03-13 |
Amgen Inc |
Variantes de inhibidor de tejido de metaloproteinasa tipo tres (timp-3), composiciones y metodos
|
|
US10323088B2
(en)
|
2014-09-22 |
2019-06-18 |
Intrinsic Lifesciences Llc |
Humanized anti-hepcidin antibodies and uses thereof
|
|
KR20230128139A
(ko)
|
2014-10-24 |
2023-09-01 |
아스트라제네카 아베 |
조합물
|
|
US9879087B2
(en)
|
2014-11-12 |
2018-01-30 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
FI3218005T3
(fi)
|
2014-11-12 |
2023-03-31 |
Seagen Inc |
Glykaanin kanssa vuorovaikutteisia yhdisteitä ja käyttömenetelmiä
|
|
US11213593B2
(en)
|
2014-11-21 |
2022-01-04 |
Northwestern University |
Sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
EP3223907A2
(en)
|
2014-11-26 |
2017-10-04 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cd38
|
|
PE20171324A1
(es)
|
2014-11-26 |
2017-09-11 |
Xencor Inc |
Anticuerpos heterodimericos que se unen a cd3 y a antigenos tumorales
|
|
CN111018987B
(zh)
|
2014-12-05 |
2023-11-21 |
鸿运华宁(杭州)生物医药有限公司 |
一种能与人内皮素受体特异性结合的抗体及其应用
|
|
ES3015000T3
(en)
|
2014-12-08 |
2025-04-28 |
Dana Farber Cancer Inst Inc |
Methods for upregulating immune responses using combinations of anti-rgmb and anti-pd-1 agents
|
|
US11697825B2
(en)
|
2014-12-12 |
2023-07-11 |
Voyager Therapeutics, Inc. |
Compositions and methods for the production of scAAV
|
|
DK3237446T3
(en)
|
2014-12-22 |
2021-07-26 |
Pd 1 Acquisition Group Llc |
Anti-PD-1-antistoffer
|
|
WO2016105450A2
(en)
|
2014-12-22 |
2016-06-30 |
Xencor, Inc. |
Trispecific antibodies
|
|
PL3240801T3
(pl)
|
2014-12-31 |
2021-06-14 |
Checkmate Pharmaceuticals, Inc. |
Skojarzona immunoterapia nowotworów
|
|
CN120988137A
(zh)
|
2015-01-23 |
2025-11-21 |
赛诺菲 |
抗cd3抗体、抗cd123抗体和与cd3和/或cd123特异性结合的双特异性抗体
|
|
US9937222B2
(en)
|
2015-01-28 |
2018-04-10 |
Ra Pharmaceuticals, Inc. |
Modulators of complement activity
|
|
AU2016215535B2
(en)
|
2015-02-04 |
2021-09-16 |
Boehringer Ingelheim International Gmbh |
Methods of treating inflammatory diseases
|
|
US10266584B2
(en)
|
2015-02-09 |
2019-04-23 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Antibodies specific to glycoprotein (GP) of Ebolavirus and uses for the treatment and diagnosis of ebola virus infection
|
|
EP3256165B1
(en)
|
2015-02-13 |
2021-07-14 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind ctla4
|
|
WO2016138160A1
(en)
|
2015-02-24 |
2016-09-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Middle east respiratory syndrome coronavirus immunogens, antibodies, and their use
|
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
|
US9951144B2
(en)
|
2015-04-08 |
2018-04-24 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind CD38
|
|
CR20170510A
(es)
|
2015-04-10 |
2018-02-26 |
Amgen Inc |
Muteínas de interuquina 2 para la expansión de células t regulatorias
|
|
CN107750255B
(zh)
|
2015-04-17 |
2022-08-30 |
安进研发(慕尼黑)股份有限公司 |
用于cdh3和cd3的双特异性抗体构建体
|
|
US20160347848A1
(en)
|
2015-05-28 |
2016-12-01 |
Medimmune Limited |
Therapeutic combinations and methods for treating neoplasia
|
|
US10519207B2
(en)
|
2015-06-12 |
2019-12-31 |
Georgia State University Research Foundation, Inc. |
Compositions and methods for treating opioid tolerance
|
|
CA2992660A1
(en)
|
2015-07-29 |
2017-02-02 |
Allergan, Inc. |
Heavy chain only antibodies to ang-2
|
|
EA039859B1
(ru)
|
2015-07-31 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
|
TWI793062B
(zh)
|
2015-07-31 |
2023-02-21 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
|
EP3334762A1
(en)
|
2015-08-14 |
2018-06-20 |
Allergan, Inc. |
Heavy chain only antibodies to pdgf
|
|
CN107922501A
(zh)
|
2015-09-01 |
2018-04-17 |
勃林格殷格翰国际有限公司 |
抗cd40抗体用于治疗狼疮性肾炎的用途
|
|
TWI799366B
(zh)
|
2015-09-15 |
2023-04-21 |
美商建南德克公司 |
胱胺酸結骨架平臺
|
|
WO2017053469A2
(en)
|
2015-09-21 |
2017-03-30 |
Aptevo Research And Development Llc |
Cd3 binding polypeptides
|
|
BR112018006237A2
(pt)
|
2015-09-29 |
2018-10-09 |
Celgene Corp |
proteínas de ligação a pd-1 e métodos de uso das mesmas
|
|
EP3356415B1
(en)
|
2015-09-29 |
2024-05-01 |
Amgen Inc. |
Asgr inhibitors for reduzing cholesterol levels
|
|
US20180280474A1
(en)
|
2015-10-01 |
2018-10-04 |
Amgen Inc. |
Treatment of bile acid disorders
|
|
EP3359575B1
(en)
|
2015-10-09 |
2020-07-22 |
Florida State University Research Foundation, Inc. |
Antibodies specific for 4,6-diamino-5-(formylamino) pyrimidine and uses thereof
|
|
US11207393B2
(en)
|
2015-10-16 |
2021-12-28 |
President And Fellows Of Harvard College |
Regulatory T cell PD-1 modulation for regulating T cell effector immune responses
|
|
CA3002097A1
(en)
|
2015-11-12 |
2017-05-18 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
CN109069871A
(zh)
|
2015-12-04 |
2018-12-21 |
加利福尼亚大学董事会 |
用于治疗癌症的新抗体
|
|
CA3007030A1
(en)
|
2015-12-07 |
2017-06-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and psma
|
|
RU2733720C2
(ru)
|
2015-12-16 |
2020-10-06 |
Ра Фармасьютикалз, Инк. |
Модуляторы активности комплемента
|
|
WO2017132562A1
(en)
|
2016-01-29 |
2017-08-03 |
Heyue Zhou |
Antigen binding proteins that bind pd-l1
|
|
EA201891753A1
(ru)
|
2016-02-03 |
2019-01-31 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкции антител к psma и cd3, вовлекающие т-клетки
|
|
IL313507A
(en)
|
2016-02-03 |
2024-08-01 |
Amgen Res Munich Gmbh |
Constructs of bispecific antibodies to BCMA and CD3 that bind to T cells, preparations containing the same and uses thereof
|
|
CN109071669A
(zh)
|
2016-03-07 |
2018-12-21 |
查尔斯顿制药有限责任公司 |
抗核仁素抗体
|
|
GB201604458D0
(en)
|
2016-03-16 |
2016-04-27 |
Immatics Biotechnologies Gmbh |
Peptides and combination of peptides for use in immunotherapy against cancers
|
|
US11510966B2
(en)
|
2016-04-15 |
2022-11-29 |
Evive Biotechnology (Shanghai) Ltd |
Use of IL-22 in treating necrotizing enterocolitis
|
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
|
JP7422480B2
(ja)
|
2016-05-04 |
2024-01-26 |
アムジエン・インコーポレーテツド |
制御性t細胞の増殖のためのインターロイキン-2変異タンパク質
|
|
TWI826351B
(zh)
|
2016-05-31 |
2023-12-21 |
大陸商鴻運華寧(杭州)生物醫藥有限公司 |
R抗體,其藥物組合物及其應用
|
|
JP7010854B2
(ja)
|
2016-06-14 |
2022-01-26 |
ゼンコア インコーポレイテッド |
二重特異性チェックポイント阻害剤抗体
|
|
CN109715663B
(zh)
|
2016-06-28 |
2022-11-25 |
Xencor股份有限公司 |
结合生长抑素受体2的异源二聚抗体
|
|
CA3029627A1
(en)
|
2016-07-01 |
2018-01-04 |
Resolve Therapeutics, Llc |
Optimized binuclease fusions and methods
|
|
MA45674A
(fr)
|
2016-07-15 |
2019-05-22 |
Takeda Pharmaceuticals Co |
Méthodes et matériaux permettant d'évaluer une réponse à des traitements de déplétion de plasmoblastes et de plasmocytes
|
|
TWI790206B
(zh)
|
2016-07-18 |
2023-01-21 |
法商賽諾菲公司 |
特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
CA3035561A1
(en)
|
2016-09-02 |
2018-03-08 |
Christopher J. Soares |
Use of cgrp receptor antagonists in neuroprotection and neurological disorders
|
|
EP3509616A1
(en)
|
2016-09-09 |
2019-07-17 |
H. Hoffnabb-La Roche Ag |
Selective peptide inhibitors of frizzled
|
|
CA3037144A1
(en)
|
2016-09-16 |
2018-03-22 |
Shanghai Henlius Biotech, Inc. |
Anti-pd-1 antibodies
|
|
MX2019002867A
(es)
|
2016-09-19 |
2019-11-12 |
Celgene Corp |
Metodos de tratamiento de trastornos inmunologicos usando proteinas de union a pd-1.
|
|
JP2019534859A
(ja)
|
2016-09-19 |
2019-12-05 |
セルジーン コーポレイション |
Pd−1結合タンパク質を使用して白斑を治療する方法
|
|
WO2018067754A1
(en)
|
2016-10-04 |
2018-04-12 |
Fairbanks Pharmaceuticals, Inc. |
Anti-fstl3 antibodies and uses thereof
|
|
IL266023B2
(en)
|
2016-10-14 |
2024-07-01 |
Neomatrix Therapeutics Inc |
Peptides Derived from Fibronectin with Improved Bioactivity and Reduced Susceptibility to Neutrophil Elastase Degradation for Use in Treating Wounds
|
|
MY203000A
(en)
|
2016-10-14 |
2024-06-01 |
Xencor Inc |
Il15/il15r� heterodimeric fc-fusion proteins
|
|
AU2017332960B2
(en)
|
2016-10-20 |
2019-09-12 |
I-Mab Biopharma Us Limited |
Novel CD47 monoclonal antibodies and uses thereof
|
|
TW202300515A
(zh)
|
2016-10-20 |
2023-01-01 |
法商賽諾菲公司 |
抗chikv抗體及其用途
|
|
US10960070B2
(en)
|
2016-10-25 |
2021-03-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Prefusion coronavirus spike proteins and their use
|
|
JP7136468B2
(ja)
|
2016-11-08 |
2022-09-13 |
ユニバーシティ オブ マイアミ |
抗セクレトグラニンiii(scg3)抗体およびその使用
|
|
WO2018094143A1
(en)
|
2016-11-17 |
2018-05-24 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
WO2018106895A1
(en)
|
2016-12-07 |
2018-06-14 |
Molecular Templates, Inc. |
Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
|
|
KR20190093196A
(ko)
|
2016-12-07 |
2019-08-08 |
라 파마슈티컬스 인코포레이티드 |
보체 활성의 조절인자
|
|
TW202130652A
(zh)
|
2017-01-19 |
2021-08-16 |
美國衛生與公眾服務部 |
Apoc-ii擬肽
|
|
SMT202500367T1
(it)
|
2017-02-02 |
2025-11-10 |
Amgen Res Munich Gmbh |
Composizione farmaceutica a basso ph comprendente costrutti di anticorpo che reclutano le cellule t
|
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
|
WO2018160909A1
(en)
|
2017-03-03 |
2018-09-07 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
GB201703876D0
(en)
|
2017-03-10 |
2017-04-26 |
Berlin-Chemie Ag |
Pharmaceutical combinations
|
|
IL269150B2
(en)
|
2017-03-16 |
2025-04-01 |
Innate Pharma |
Cancer treatment preparations and methods
|
|
JP2020512344A
(ja)
|
2017-03-27 |
2020-04-23 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
抗il−36r抗体併用治療
|
|
US10729741B2
(en)
|
2017-03-27 |
2020-08-04 |
Neomatrix Therapeutics Inc. |
Methods of treating burns with i.v. cP12 in a window from 2 to 6 hours after injury
|
|
EP3615569A1
(en)
|
2017-04-25 |
2020-03-04 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
|
|
UY37726A
(es)
|
2017-05-05 |
2018-11-30 |
Amgen Inc |
Composición farmacéutica que comprende constructos de anticuerpos biespecíficos para almacenamiento y administración mejorados
|
|
CA3102086A1
(en)
|
2017-06-06 |
2018-12-13 |
Relinia, Inc. |
Single-chain tnf receptor 2 agonist fusion proteins
|
|
US10793634B2
(en)
|
2017-06-09 |
2020-10-06 |
Boehringer Ingelheim International Gmbh |
Anti-TrkB antibodies
|
|
WO2019006472A1
(en)
|
2017-06-30 |
2019-01-03 |
Xencor, Inc. |
TARGETED HETETRODIMERIC FUSION PROTEINS CONTAINING IL-15 / IL-15RA AND ANTIGEN-BINDING DOMAINS
|
|
EP4424366A3
(en)
|
2017-07-07 |
2024-12-04 |
Takeda Pharmaceutical Company Limited |
Treatment of gastrointestinal bleeding in patients with severe von willebrand disease by administration of recombinant vwf
|
|
KR102788331B1
(ko)
|
2017-07-07 |
2025-03-27 |
다케다 야쿠힌 고교 가부시키가이샤 |
재조합 vwf의 투여에 의해 대기 수술을 받은 중증 폰 빌레브란트 병을 가지고 있는 환자의 치료
|
|
WO2019018629A1
(en)
|
2017-07-19 |
2019-01-24 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING INFECTION WITH HEPATITIS B VIRUS
|
|
CN111201030B
(zh)
|
2017-07-25 |
2024-11-01 |
真和制药有限公司 |
通过阻断tim-3和其配体的相互作用治疗癌症
|
|
CA3073537A1
(en)
|
2017-08-22 |
2019-02-28 |
Sanabio, Llc |
Soluble interferon receptors and uses thereof
|
|
WO2019070086A2
(en)
*
|
2017-09-20 |
2019-04-11 |
RIM, Chang Ho |
BLOOD SUBSTITUTE CARRYING OXYGEN OBTAINED FROM PORK BLOOD AND METHOD OF MAKING SAME
|
|
AU2018361819B2
(en)
|
2017-11-02 |
2025-01-09 |
Oxford Biotherapeutics Ltd |
Antibodies and methods of use
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
JP2021502100A
(ja)
|
2017-11-08 |
2021-01-28 |
ゼンコア インコーポレイテッド |
新規抗pd−1配列を用いた二重特異性および単一特異性抗体
|
|
RS67119B1
(sr)
|
2017-11-14 |
2025-09-30 |
Arcellx Inc |
Polipeptidi koji obuhvataju d domen i njihove upotrebe
|
|
AU2018383679B2
(en)
|
2017-12-11 |
2025-10-09 |
Amgen Inc. |
Continuous manufacturing process for bispecific antibody products
|
|
IL275426B2
(en)
|
2017-12-19 |
2025-03-01 |
Xencor Inc |
Engineered il-2 fc fusion proteins
|
|
TW201940518A
(zh)
|
2017-12-29 |
2019-10-16 |
美商安進公司 |
針對muc17和cd3之雙特異性抗體構建體
|
|
JP7490565B2
(ja)
|
2017-12-29 |
2024-05-27 |
アレクトル エルエルシー |
抗tmem106b抗体及びその使用方法
|
|
EP4506017A3
(en)
|
2018-01-03 |
2025-05-14 |
Mederis Diabetes, LLC |
Improved peptide pharmaceuticals for treatment of nash and other disorders
|
|
CR20200327A
(es)
|
2018-01-26 |
2020-11-05 |
Genentech Inc |
Proteínas de fusión fc il-22 y métodos de uso
|
|
CN112020365A
(zh)
|
2018-01-26 |
2020-12-01 |
豪夫迈·罗氏有限公司 |
组合物和使用方法
|
|
US11472874B2
(en)
|
2018-01-31 |
2022-10-18 |
Alector Llc |
Anti-MS4A4A antibodies and methods of use thereof
|
|
WO2019160866A2
(en)
|
2018-02-13 |
2019-08-22 |
Checkmate Pharmaceuticals, Inc. |
Compositions and methods for tumor immunotherapy
|
|
KR20250139415A
(ko)
|
2018-02-14 |
2025-09-23 |
호라이즌 테라퓨틱스 아일랜드 디에이씨 |
고양이 맥도너 육종(fms)-유사 티로신 키나제 3 수용체 리간드(flt3l)에 대한 항체 및 자가면역 및 염증 질환을 치료하기 위한 이의 용도
|
|
KR20200123118A
(ko)
|
2018-02-21 |
2020-10-28 |
제넨테크, 인크. |
IL-22 Fc 융합 단백질로 치료를 위한 투약
|
|
WO2019168897A2
(en)
|
2018-02-28 |
2019-09-06 |
Dana-Farber Cancer Institute, Inc. |
Methods for treating cancer using combinations of anti-btnl2 and immune checkpoint blockade agents
|
|
EP3765522A4
(en)
|
2018-03-14 |
2022-05-18 |
Beijing Xuanyi Pharmasciences Co., Ltd. |
ANTI-CLAUDIN 18.2 ANTIBODIES
|
|
CN117126279A
(zh)
|
2018-03-20 |
2023-11-28 |
鸿运华宁(杭州)生物医药有限公司 |
Gipr抗体及其与glp-1的融合蛋白质,以及其药物组合物和应用
|
|
IL277464B1
(en)
|
2018-03-21 |
2026-04-01 |
Baxalta Inc |
Separation of VWF and VWF propeptide using chromatographic methods
|
|
CA3096052A1
(en)
|
2018-04-04 |
2019-10-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
|
JP7429192B2
(ja)
|
2018-04-06 |
2024-02-07 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
Hhla2受容体としてのkir3dl3、抗hhla2抗体、およびその使用
|
|
EP3774916A2
(en)
|
2018-04-06 |
2021-02-17 |
Biolegend, Inc. |
Anti-tetraspanin 33 agents and compositions and methods for making and using the same
|
|
BR112020020479A2
(pt)
|
2018-04-09 |
2021-01-12 |
Checkmate Pharmaceuticals |
Empacotamento de oligonucleotídeos em partículas similares a vírus
|
|
CN110357959B
(zh)
|
2018-04-10 |
2023-02-28 |
鸿运华宁(杭州)生物医药有限公司 |
Gcgr抗体及其与glp-1的融合蛋白质,以及其药物组合物和应用
|
|
SG11202010163QA
(en)
|
2018-04-18 |
2020-11-27 |
Xencor Inc |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
EP3781598A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
|
KR20210005097A
(ko)
|
2018-04-30 |
2021-01-13 |
메디뮨 리미티드 |
응집체를 표적화하고 제거하는 접합체
|
|
WO2019211665A1
(en)
|
2018-04-30 |
2019-11-07 |
Takeda Pharmaceutical Company Limited |
Cannabinoid receptor type 1 (cb1) binding proteins and uses thereof
|
|
WO2019213416A1
(en)
|
2018-05-02 |
2019-11-07 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
|
|
JP7337099B2
(ja)
|
2018-05-25 |
2023-09-01 |
アレクトル エルエルシー |
抗sirpa抗体およびその使用法
|
|
TWI851577B
(zh)
|
2018-06-07 |
2024-08-11 |
美商思進公司 |
喜樹鹼結合物
|
|
CN110655577A
(zh)
|
2018-06-13 |
2020-01-07 |
鸿运华宁(杭州)生物医药有限公司 |
APJ抗体及其与Elabela的融合蛋白质,以及其药物组合物和应用
|
|
GB201809746D0
(en)
|
2018-06-14 |
2018-08-01 |
Berlin Chemie Ag |
Pharmaceutical combinations
|
|
DK3807316T3
(da)
|
2018-06-18 |
2024-07-29 |
Innate Pharma |
Sammensætninger og fremgangsmåder til behandling af cancer
|
|
EP3806889A4
(en)
|
2018-06-18 |
2022-07-13 |
Anwita Biosciences, Inc. |
CYTOKI FUSION PROTEINS AND USES THEREOF
|
|
KR20250156190A
(ko)
|
2018-06-22 |
2025-10-31 |
큐진 인크. |
인터루킨-2 변이체 및 이의 사용 방법
|
|
BR112020026819A2
(pt)
|
2018-06-29 |
2021-04-20 |
Alector Llc |
anticorpos isolados, ácido nucleico, vetor, células hospedeiras, método de produção de um anticorpo, composição farmacêutica, métodos para tratar o câncer e para tratar uma doença e usos de um anticorpo
|
|
WO2020006347A1
(en)
|
2018-06-29 |
2020-01-02 |
Boehringer Ingelheim International Gmbh |
Anti-cd40 antibodies for use in treating autoimmune disease
|
|
TW202519260A
(zh)
|
2018-07-02 |
2025-05-16 |
美商安進公司 |
抗steap1抗原結合蛋白
|
|
LT3618928T
(lt)
|
2018-07-13 |
2023-04-11 |
Alector Llc |
Anti-sortilino antikūnai ir jų panaudojimo būdai
|
|
WO2020021061A1
(en)
|
2018-07-26 |
2020-01-30 |
Pieris Pharmaceuticals Gmbh |
Humanized anti-pd-1 antibodies and uses thereof
|
|
CA3107186A1
(en)
|
2018-07-30 |
2020-02-06 |
Amgen Research (Munich) Gmbh |
Prolonged administration of a bispecific antibody construct binding to cd33 and cd3
|
|
WO2020025792A1
(en)
|
2018-08-03 |
2020-02-06 |
Amgen Research (Munich) Gmbh |
Antibody constructs for cldn18.2 and cd3
|
|
US20210347848A1
(en)
|
2018-08-31 |
2021-11-11 |
ALX Oncology Inc. |
Decoy polypeptides
|
|
WO2020068653A1
(en)
|
2018-09-24 |
2020-04-02 |
Aerpio Pharmaceuticals, Inc. |
MULTISPECIFIC ANTIBODIES THAT TARGET HPTP - β (VE-PTP) AND VEGF
|
|
CN113365697B
(zh)
|
2018-09-25 |
2024-07-19 |
百进生物科技公司 |
抗tlr9药剂和组合物及其制备方法和使用方法
|
|
BR112021005585A2
(pt)
|
2018-09-27 |
2021-06-29 |
Celgene Corporation |
proteínas de ligação a sirpa e métodos de uso das mesmas
|
|
WO2020065594A1
(en)
|
2018-09-28 |
2020-04-02 |
Kyowa Kirin Co., Ltd. |
Il-36 antibodies and uses thereof
|
|
AU2019355971B2
(en)
|
2018-10-03 |
2025-05-08 |
Xencor, Inc. |
IL-12 heterodimeric Fc-fusion proteins
|
|
JP7644706B2
(ja)
|
2018-10-11 |
2025-03-12 |
アムジエン・インコーポレーテツド |
二重特異性抗体コンストラクトの下流プロセシング
|
|
JP2022513082A
(ja)
|
2018-11-19 |
2022-02-07 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
免疫応答を調節するためのIRE1α-XBP1シグナル伝達経路バイオマーカーの使用
|
|
AU2019392090A1
(en)
|
2018-12-03 |
2021-06-17 |
Agensys, Inc. |
Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof
|
|
WO2020142740A1
(en)
|
2019-01-04 |
2020-07-09 |
Resolve Therapeutics, Llc |
Treatment of sjogren's disease with nuclease fusion proteins
|
|
WO2020160156A2
(en)
|
2019-01-30 |
2020-08-06 |
Immutics, Inc. |
Anti-gal3 antibodies and uses thereof
|
|
EA202192140A1
(ru)
|
2019-02-01 |
2021-12-15 |
Такеда Фармасьютикал Компани Лимитед |
СПОСОБЫ ПРОФИЛАКТИЧЕСКОГО ЛЕЧЕНИЯ РЕКОМБИНАНТНЫМ ФВ (рФВ)
|
|
EP3693023A1
(en)
|
2019-02-11 |
2020-08-12 |
Sanofi |
Use of anti-ceacam5 immunoconjugates for treating lung cancer
|
|
WO2020161214A1
(en)
|
2019-02-07 |
2020-08-13 |
Sanofi |
Use of anti-ceacam5 immunoconjugates for treating lung cancer
|
|
AU2020227824B2
(en)
|
2019-02-27 |
2025-07-10 |
Ionis Pharmaceuticals, Inc. |
Modulators of MALAT1 expression
|
|
CA3132185A1
(en)
|
2019-03-01 |
2020-09-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
|
WO2020191365A1
(en)
|
2019-03-21 |
2020-09-24 |
Gigamune, Inc. |
Engineered cells expressing anti-viral t cell receptors and methods of use thereof
|
|
CN114096559B
(zh)
|
2019-03-27 |
2026-03-20 |
蒂嘉特克斯公司 |
工程化iga抗体及其使用方法
|
|
AU2020272939A1
(en)
|
2019-04-09 |
2021-11-11 |
Abcuro, Inc. |
Killer cell lectin-like receptor subfamily G member 1 (KLRG1) depleting antibodies
|
|
EP3962529A4
(en)
|
2019-04-30 |
2023-11-01 |
Dana-Farber Cancer Institute, Inc. |
Methods for treating cancer using combinations of anti-cx3cr1 and immune checkpoint blockade agents
|
|
CN113728003A
(zh)
|
2019-04-30 |
2021-11-30 |
吉加根公司 |
重组多克隆蛋白及其使用方法
|
|
WO2020225400A1
(en)
|
2019-05-09 |
2020-11-12 |
Boehringer Ingelheim International Gmbh |
Anti-sema3a antibodies and their uses for treating eye or ocular diseases
|
|
JP2022535411A
(ja)
|
2019-06-04 |
2022-08-08 |
ラ ファーマシューティカルズ インコーポレイテッド |
補体阻害剤による炎症性疾患治療
|
|
MX2021014644A
(es)
|
2019-06-13 |
2022-04-06 |
Amgen Inc |
Control de perfusion basado en biomasa automatizado en la fabricacion de productos biologicos.
|
|
TWI877179B
(zh)
|
2019-06-27 |
2025-03-21 |
德商百靈佳殷格翰國際股份有限公司 |
抗-angpt2抗體
|
|
AU2020298833A1
(en)
|
2019-07-03 |
2022-01-20 |
Oxford Biotherapeutics Ltd |
Antibodies and methods of use
|
|
CN112239507A
(zh)
|
2019-07-17 |
2021-01-19 |
鸿运华宁(杭州)生物医药有限公司 |
ETA抗体与TGF-β Trap的融合蛋白质,以及其药物组合物和应用
|
|
CN112300279A
(zh)
|
2019-07-26 |
2021-02-02 |
上海复宏汉霖生物技术股份有限公司 |
针对抗cd73抗体和变体的方法和组合物
|
|
CA3145885A1
(en)
|
2019-07-31 |
2021-02-04 |
Jeonghoon Sun |
Anti-ms4a4a antibodies and methods of use thereof
|
|
WO2021023624A1
(en)
|
2019-08-02 |
2021-02-11 |
Orega Biotech |
Novel il-17b antibodies
|
|
US20210032370A1
(en)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Recruiting agent further binding an mhc molecule
|
|
DE102019121007A1
(de)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Antigenbindende Proteine, die spezifisch an MAGE-A binden
|
|
PH12022550326A1
(en)
|
2019-08-13 |
2023-03-13 |
Amgen Inc |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
|
TW202535466A
(zh)
|
2019-09-09 |
2025-09-16 |
德商百靈佳殷格翰國際股份有限公司 |
抗-il-23p19抗體調配物
|
|
US20220306741A1
(en)
|
2019-09-10 |
2022-09-29 |
Amgen Inc. |
Purification Method for Bispecific antigen-binding Polypeptides with Enhanced Protein L Capture Dynamic Binding Capacity
|
|
CN114929260A
(zh)
|
2019-09-11 |
2022-08-19 |
武田药品工业株式会社 |
与冯维勒布兰德因子和补体c1q的复合物相关的治疗方法
|
|
CN112521501A
(zh)
|
2019-09-18 |
2021-03-19 |
鸿运华宁(杭州)生物医药有限公司 |
Gipr抗体及其与glp-1的融合蛋白质,以及其药物组合物和应用
|
|
TWI859339B
(zh)
|
2019-09-24 |
2024-10-21 |
德商百靈佳殷格翰國際股份有限公司 |
抗nrp1a抗體及其用於治療眼或眼部疾病之用途
|
|
WO2021091885A2
(en)
|
2019-11-04 |
2021-05-14 |
Alector Llc |
Siglec-9 ecd fusion molecules and methods of use thereof
|
|
US20220396599A1
(en)
|
2019-11-13 |
2022-12-15 |
Amgen Inc. |
Method for Reduced Aggregate Formation in Downstream Processing of Bispecific Antigen-Binding Molecules
|
|
AU2020397416A1
(en)
|
2019-12-03 |
2022-07-14 |
Evotec International Gmbh |
Interferon-associated antigen binding proteins for use in treating hepatitis B infection
|
|
US20230242655A1
(en)
|
2019-12-03 |
2023-08-03 |
Evotec International Gmbh |
Interferon-associated antigen binding proteins and uses thereof
|
|
US20210221886A1
(en)
|
2019-12-05 |
2021-07-22 |
Sorrento Therapeutics, Inc. |
Compositions and Methods Comprising an Anti-CD47 Antibody in Combination with a Tumor Targeting Antibody
|
|
MX2022007231A
(es)
|
2019-12-13 |
2022-07-12 |
Alector Llc |
Anticuerpos anti-mertk y metodos de uso de los mismos.
|
|
IL293471A
(en)
|
2019-12-17 |
2022-08-01 |
Amgen Inc |
Dual interleukin-2 / tnf receptor agonist for use in medicine
|
|
CA3162011A1
(en)
|
2019-12-19 |
2021-06-24 |
Rodolphe SORET |
Use of glial cell line-derived neurotrophic factor (gdnf) for the treatment of enteric neuropathies
|
|
EP4090365A1
(en)
|
2020-01-15 |
2022-11-23 |
Immatics Biotechnologies GmbH |
Antigen binding proteins specifically binding prame
|
|
WO2021146383A1
(en)
|
2020-01-17 |
2021-07-22 |
BioLegend, Inc. |
Anti-tlr7 agents and compositions and methods for making and using the same
|
|
US20230093169A1
(en)
|
2020-01-22 |
2023-03-23 |
Amgen Research (Munch) Gmbh |
Combinations of antibody constructs and inhibitors of cytokine release syndrome and uses thereof
|
|
EP4093513A4
(en)
|
2020-01-24 |
2024-05-08 |
Dana-Farber Cancer Institute, Inc. |
Uses of biomarkers for improving immunotherapy
|
|
CN115335074A
(zh)
|
2020-02-04 |
2022-11-11 |
武田药品工业株式会社 |
通过施用重组vwf来治疗患有重度冯维勒布兰德病的患者的月经过多
|
|
EP4106794A4
(en)
|
2020-02-19 |
2024-03-20 |
Evive Biotechnology (Shanghai) Ltd |
METHOD FOR TREATING TRANSPLANT AND HOST DISEASE
|
|
CA3168986A1
(en)
|
2020-02-26 |
2021-09-02 |
Sorrento Therapeutics, Inc. |
Activatable antigen binding proteins with universal masking moieties
|
|
TW202200615A
(zh)
|
2020-03-12 |
2022-01-01 |
美商安進公司 |
用於治療和預防患者的crs之方法
|
|
WO2021195089A1
(en)
|
2020-03-23 |
2021-09-30 |
Sorrento Therapeutics, Inc. |
Fc-coronavirus antigen fusion proteins, and nucleic acids, vectors, compositions and methods of use thereof
|
|
CN116075525A
(zh)
|
2020-03-31 |
2023-05-05 |
艾莱克特有限责任公司 |
抗mertk抗体及其使用方法
|
|
WO2021207662A1
(en)
|
2020-04-10 |
2021-10-14 |
Genentech, Inc. |
Use of il-22fc for the treatment or prevention of pneumonia, acute respiratory distress syndrome, or cytokine release syndrome
|
|
JP7713956B2
(ja)
|
2020-04-15 |
2025-07-28 |
ボイジャー セラピューティクス インコーポレイテッド |
タウ結合化合物
|
|
US20230158125A1
(en)
|
2020-04-20 |
2023-05-25 |
Sorrento Therapeutics, Inc. |
Pulmonary Administration of ACE2 Polypeptides
|
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
|
CA3183756A1
(en)
|
2020-05-19 |
2021-11-25 |
Amgen Inc. |
Mageb2 binding constructs
|
|
CR20220596A
(es)
|
2020-05-26 |
2023-01-23 |
Boehringer Ingelheim Int |
Anticuerpos anti-pd-1
|
|
EP4157338A4
(en)
|
2020-05-26 |
2024-11-13 |
TrueBinding, Inc. |
METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
|
|
US20240209085A1
(en)
|
2020-05-29 |
2024-06-27 |
Amgen Inc. |
Adverse effects-mitigating administration of a bispecific construct binding to cd33 and cd3
|
|
WO2021253002A1
(en)
|
2020-06-12 |
2021-12-16 |
Gigagen, Inc. |
Recombinant polyclonal proteins targeting covid-19 and methods of use thereof
|
|
CN116670285A
(zh)
|
2020-06-23 |
2023-08-29 |
江苏康缘药业股份有限公司 |
抗cd38抗体及其用途
|
|
US20230235059A1
(en)
|
2020-06-26 |
2023-07-27 |
Sorrento Therapeutics, Inc. |
Anti-pd1 antibodies and uses thereof
|
|
CA3165342A1
(en)
|
2020-06-29 |
2022-01-06 |
James Arthur Posada |
Treatment of sjogren's syndrome with nuclease fusion proteins
|
|
JP7846667B2
(ja)
|
2020-07-16 |
2026-04-15 |
レジェンド バイオテック アイルランド リミテッド |
Cd20結合分子及びその使用
|
|
JP2023537470A
(ja)
|
2020-08-03 |
2023-09-01 |
ヤンセン バイオテツク,インコーポレーテツド |
ウイルス治療における多方向バイオ輸送のための材料及び方法
|
|
WO2022031834A1
(en)
|
2020-08-05 |
2022-02-10 |
Gigagen, Inc. |
Recombinant polyclonal proteins targeting zika and methods of use thereof
|
|
AU2021335257A1
(en)
|
2020-09-04 |
2023-03-09 |
Merck Patent Gmbh |
Anti-CEACAM5 antibodies and conjugates and uses thereof
|
|
EP4213939A1
(en)
|
2020-09-21 |
2023-07-26 |
Boehringer Ingelheim International GmbH |
Use of anti-cd40 antibodies for treatment of inflammatory conditions
|
|
US20230381293A1
(en)
|
2020-10-14 |
2023-11-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic |
Stabilized norovirus virus-like particles as vaccine immunogens
|
|
US20220127344A1
(en)
|
2020-10-23 |
2022-04-28 |
Boehringer Ingelheim International Gmbh |
Anti-sema3a antibodies and their uses for treating a thrombotic disease of the retina
|
|
WO2022093641A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2a agents and compositions and methods for making and using the same
|
|
WO2022093640A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2c agents and compositions and methods for making and using the same
|
|
CR20230229A
(es)
|
2020-11-06 |
2023-09-05 |
Amgen Res Munich Gmbh |
Moléculas de unión a antígeno biespecíficas con múltiples dianas de selectividad aumentada
|
|
UY39507A
(es)
|
2020-11-06 |
2022-03-31 |
Amgen Res Munich Gmbh |
Construcciones polipeptídicas que se unen selectivamente a cldn6 y cd3
|
|
WO2022096704A1
(en)
|
2020-11-06 |
2022-05-12 |
Amgen Inc. |
Antigen binding domain with reduced clipping rate
|
|
TW202225188A
(zh)
|
2020-11-06 |
2022-07-01 |
德商安美基研究(慕尼黑)公司 |
與cd3結合的多肽構建體
|
|
AU2021379882A1
(en)
|
2020-11-10 |
2023-06-29 |
Sanofi |
Ceacam5 antibody-drug conjugate formulation
|
|
CN117202924A
(zh)
|
2020-12-07 |
2023-12-08 |
斯皮特弗尔制药有限责任公司 |
使用glp-1r和gcgr平衡激动剂降低血糖和/或体重的治疗方案和方法
|
|
CN117043183A
(zh)
|
2020-12-16 |
2023-11-10 |
沃雅戈治疗公司 |
Tau结合化合物
|
|
JP2024502832A
(ja)
|
2020-12-31 |
2024-01-23 |
アラマー バイオサイエンシーズ, インコーポレイテッド |
高親和性及び/または特異性を有する結合剤分子ならびにその製造及び使用方法
|
|
US20250282870A1
(en)
|
2021-01-20 |
2025-09-11 |
Bioentre Llc |
Ctla4-binding proteins and methods of treating cancer
|
|
EP4284828A1
(en)
|
2021-01-28 |
2023-12-06 |
Talem Therapeutics LLC |
Anti-sars-cov-2 spike glycoprotein antibodies and the therapeutic use thereof
|
|
CN117062836A
(zh)
|
2021-02-05 |
2023-11-14 |
勃林格殷格翰国际有限公司 |
抗il1rap抗体
|
|
US11739144B2
(en)
|
2021-03-09 |
2023-08-29 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and CLDN6
|
|
EP4305065A1
(en)
|
2021-03-10 |
2024-01-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
|
BR112023018676A2
(pt)
|
2021-03-18 |
2023-10-10 |
Seagen Inc |
Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco
|
|
WO2022197947A1
(en)
|
2021-03-18 |
2022-09-22 |
Alector Llc |
Anti-tmem106b antibodies and methods of use thereof
|
|
JP2024511610A
(ja)
|
2021-03-23 |
2024-03-14 |
アレクトル エルエルシー |
コロナウイルス感染の治療及び予防のための抗tmem106b抗体
|
|
CA3212311A1
(en)
|
2021-03-26 |
2022-09-29 |
Abcuro, Inc. |
Anti-klrg1 antibodies
|
|
WO2022204529A1
(en)
|
2021-03-26 |
2022-09-29 |
Abcuro, Inc. |
Anti-klrg1 antibodies
|
|
CN115141276A
(zh)
|
2021-03-31 |
2022-10-04 |
鸿运华宁(杭州)生物医药有限公司 |
一种能与人内皮素受体特异性结合的抗体及其在糖尿病肾病和慢性肾病治疗中的应用
|
|
WO2022212836A1
(en)
|
2021-04-01 |
2022-10-06 |
Pyxis Oncology, Inc. |
Gpnmb antibodies and methods of use
|
|
US20250282887A1
(en)
|
2021-04-02 |
2025-09-11 |
Amgen Inc. |
Mageb2 binding constructs
|
|
JP2024518369A
(ja)
|
2021-05-06 |
2024-05-01 |
アムジェン リサーチ (ミュニック) ゲゼルシャフト ミット ベシュレンクテル ハフツング |
増殖性疾患で使用されるcd20及びcd22標的化抗原結合分子
|
|
TW202317620A
(zh)
|
2021-06-04 |
2023-05-01 |
德商百靈佳殷格翰國際股份有限公司 |
抗SIRPα抗體
|
|
US20240280561A1
(en)
|
2021-06-08 |
2024-08-22 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating and/or identifying an agent for treating intestinal cancers
|
|
EP4351732A1
(en)
|
2021-06-09 |
2024-04-17 |
Evotec International GmbH |
Interferon-associated antigen binding proteins for use for the treatment or prevention of coronavirus infection
|
|
WO2022266221A1
(en)
|
2021-06-16 |
2022-12-22 |
Alector Llc |
Monovalent anti-mertk antibodies and methods of use thereof
|
|
EP4355786A1
(en)
|
2021-06-16 |
2024-04-24 |
Alector LLC |
Bispecific anti-mertk and anti-pdl1 antibodies and methods of use thereof
|
|
WO2023009498A1
(en)
|
2021-07-26 |
2023-02-02 |
Abcuro, Inc. |
Killer cell lectin-like receptor subfamily g member 1 (klrg1) depleting antibodies
|
|
WO2023069919A1
(en)
|
2021-10-19 |
2023-04-27 |
Alector Llc |
Anti-cd300lb antibodies and methods of use thereof
|
|
WO2023097119A2
(en)
|
2021-11-29 |
2023-06-01 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions to modulate riok2
|
|
AU2022402334A1
(en)
|
2021-12-02 |
2024-07-18 |
Sanofi |
Ceacam5 adc–anti-pd1/pd-l1 combination therapy
|
|
EP4440603A1
(en)
|
2021-12-02 |
2024-10-09 |
Sanofi |
Cea assay for patient selection in cancer therapy
|
|
CR20240265A
(es)
|
2021-12-22 |
2024-10-16 |
Boehringer Ingelheim Int |
Anticuerpos anti-c3 y fragmentos de unión al antígeno de estos y sus usos para tratar enfermedades oftálmicas u oculares
|
|
UY40097A
(es)
|
2022-01-07 |
2023-07-14 |
Johnson & Johnson Entpr Innovation Inc |
Materiales y métodos de proteínas de unión a il-1b
|
|
WO2023172968A1
(en)
|
2022-03-09 |
2023-09-14 |
Merck Patent Gmbh |
Anti-gd2 antibodies, immunoconjugates and therapeutic uses thereof
|
|
US20250179210A1
(en)
|
2022-03-09 |
2025-06-05 |
Merck Patent Gmbh |
Anti-ceacam5 antibodies and conjugates and uses thereof
|
|
WO2023194333A1
(en)
|
2022-04-04 |
2023-10-12 |
Swiftpharma Bv |
Recombinant spider silk-reinforced collagen proteins produced in plants and the use thereof
|
|
EP4522651A1
(en)
|
2022-05-12 |
2025-03-19 |
Amgen Research (Munich) GmbH |
Multichain multitargeting bispecific antigen-binding molecules of increased selectivity
|
|
WO2023240287A1
(en)
|
2022-06-10 |
2023-12-14 |
Bioentre Llc |
Combinations of ctla4 binding proteins and methods of treating cancer
|
|
EP4543473A1
(en)
|
2022-06-22 |
2025-04-30 |
Voyager Therapeutics, Inc. |
Tau binding compounds
|
|
JP2025525530A
(ja)
|
2022-07-15 |
2025-08-05 |
ヤンセン バイオテツク,インコーポレーテツド |
抗原結合可変領域の改善された生物工学による対合のための材料及び方法
|
|
EP4558523A1
(en)
|
2022-07-19 |
2025-05-28 |
Biolegend, Inc. |
Anti-cd157 antibodies, antigen-binding fragments thereof and compositions and methods for making and using the same
|
|
MA71628A
(fr)
|
2022-07-29 |
2025-05-30 |
Alector Llc |
Anticorps anti-gpnmb et leurs méthodes d'utilisation
|
|
CN119968395A
(zh)
|
2022-08-18 |
2025-05-09 |
百进生物科技公司 |
抗axl抗体、其抗原结合片段及其制备和使用方法
|
|
CN119744271A
(zh)
|
2022-09-08 |
2025-04-01 |
鸿运华宁(杭州)生物医药有限公司 |
Gipr抗体及其与fgf21的融合蛋白,以及其药物组合物和应用
|
|
TW202421650A
(zh)
|
2022-09-14 |
2024-06-01 |
美商安進公司 |
雙特異性分子穩定組成物
|
|
WO2024081918A1
(en)
|
2022-10-14 |
2024-04-18 |
Talem Therapeutics Llc |
Anti-trkb/cd3 antibodies and uses thereof
|
|
WO2024086796A1
(en)
|
2022-10-20 |
2024-04-25 |
Alector Llc |
Anti-ms4a4a antibodies with amyloid-beta therapies
|
|
EP4615480A1
(en)
|
2022-11-07 |
2025-09-17 |
Alector LLC |
Uses of siglec-9 ecd fusion molecules in cancer treatment
|
|
EP4619045A1
(en)
|
2022-11-17 |
2025-09-24 |
Sanofi |
Ceacam5 antibody-drug conjugates and methods of use thereof
|
|
WO2024126293A1
(en)
|
2022-12-13 |
2024-06-20 |
Evotec International Gmbh |
Interferon-associated antigen binding proteins for use for the treatment or prevention of respiratory syncytial virus infection
|
|
WO2024126294A1
(en)
|
2022-12-13 |
2024-06-20 |
Evotec International Gmbh |
Interferon-associated antigen binding proteins for use for the treatment or prevention of parainfluenza virus infection
|
|
WO2024126289A1
(en)
|
2022-12-13 |
2024-06-20 |
Evotec International Gmbh |
Interferon-associated antigen binding proteins for use for the treatment or prevention of influenza virus infection
|
|
WO2024148232A2
(en)
|
2023-01-06 |
2024-07-11 |
Alector Llc |
Anti-il18 binding protein antibodies and methods of use thereof
|
|
CN121127494A
(zh)
|
2023-01-06 |
2025-12-12 |
武田药品工业株式会社 |
用于治疗自身免疫性疾病的抗cd38抗体
|
|
WO2024213635A1
(en)
|
2023-04-12 |
2024-10-17 |
Evotec International Gmbh |
Interferon-associated antigen binding proteins for use for the treatment or prevention of hepatitis delta virus infection
|
|
WO2024243217A1
(en)
|
2023-05-25 |
2024-11-28 |
BioLegend, Inc. |
Ceacam6 binding antibodies and antigen-binding fragments thereof
|
|
CN121712787A
(zh)
|
2023-06-14 |
2026-03-20 |
马里亚纳肿瘤学公司 |
靶向dll3的肽及其构建体
|
|
KR20260026051A
(ko)
|
2023-06-14 |
2026-02-25 |
마리아나 온콜로지 인크. |
Dll3 표적화 펩티드 및 이의 구성체
|
|
CN121712788A
(zh)
|
2023-06-14 |
2026-03-20 |
马里亚纳肿瘤学公司 |
靶向dll3的肽及其构建体
|
|
UY40797A
(es)
|
2023-06-14 |
2024-12-31 |
Amgen Inc |
Moléculas captadoras de enmascaramiento de células t
|
|
CN121358777A
(zh)
|
2023-07-27 |
2026-01-16 |
伊玛提克斯生物技术有限公司 |
抗mageb2的抗原结合蛋白
|
|
WO2025037108A2
(en)
|
2023-08-15 |
2025-02-20 |
Board Of Trustees Of The Leland Stanford Junior University |
Modified thrombopoietin
|
|
WO2025038732A1
(en)
|
2023-08-15 |
2025-02-20 |
Gigagen, Inc. |
Recombinant polyclonal proteins targeting hepatitis b virus (hbv) and methods of use thereof
|
|
CN121816366A
(zh)
|
2023-09-27 |
2026-04-07 |
百进公司 |
抗gpc4抗体
|
|
WO2025072726A1
(en)
|
2023-09-29 |
2025-04-03 |
Trex Bio, Inc. |
Tnf-alpha variant fusion molecules
|
|
WO2025074337A1
(en)
|
2023-10-06 |
2025-04-10 |
Boehringer Ingelheim International Gmbh |
Use of anti-sirp-alpha antibodies to treat a liver disease or disorder
|
|
WO2025074328A1
(en)
|
2023-10-06 |
2025-04-10 |
Boehringer Ingelheim International Gmbh |
Use of anti-sirp-alpha antibodies to treat cancer
|
|
WO2025117586A1
(en)
|
2023-11-27 |
2025-06-05 |
Mariana Oncology Inc. |
Dll3 targeting peptides and constructs thereof
|
|
WO2025122615A1
(en)
|
2023-12-05 |
2025-06-12 |
Mariana Oncology Inc. |
Enriched and stable radioligand therapy formulations and pharmaceutical compositions comprising same
|
|
WO2025147544A1
(en)
|
2024-01-02 |
2025-07-10 |
Abcuro, Inc. |
Methods of treating inclusion body myositis (ibm)
|
|
WO2025147696A1
(en)
|
2024-01-05 |
2025-07-10 |
Resolve Therapeutics, Llc |
Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
|
|
WO2025155843A1
(en)
|
2024-01-19 |
2025-07-24 |
Akero Therapeutics, Inc. |
Method of treating liver or lung injury
|
|
TW202600175A
(zh)
|
2024-02-15 |
2026-01-01 |
德商馬克專利公司 |
用於治療gd2陽性癌症之抗gd2抗體及免疫結合物
|
|
WO2025181215A1
(en)
|
2024-03-01 |
2025-09-04 |
Boehringer Ingelheim International Gmbh |
Antibodies to connective tissue growth factor (ctgf) and uses thereof
|
|
WO2025193746A1
(en)
|
2024-03-12 |
2025-09-18 |
Takeda Pharmaceutical Company Limited |
Dosing regimens of anti-cd38 antibodies for treatment of subjects with immune thrombocytopenia
|
|
WO2025196639A1
(en)
|
2024-03-21 |
2025-09-25 |
Seagen Inc. |
Cd25 antibodies, antibody-drug conjugates, and uses thereof
|
|
WO2025210264A1
(en)
|
2024-04-04 |
2025-10-09 |
Merck Patent Gmbh |
Antibody-drug-conjugates binding napi2b
|
|
WO2025235919A1
(en)
|
2024-05-09 |
2025-11-13 |
Takeda Pharmaceutical Company Limited |
Dosing regimens of anti-cd38 antibodies for treatment of subjects with immunoglobulin a nephropathy
|
|
WO2025242845A1
(en)
|
2024-05-22 |
2025-11-27 |
Merck Patent Gmbh |
Colorectal cancer treatment
|
|
WO2025254987A1
(en)
|
2024-06-03 |
2025-12-11 |
Alector Llc |
Siglec-9 ecd fusion molecule variants and methods of use thereof
|
|
WO2026024904A1
(en)
|
2024-07-24 |
2026-01-29 |
Gigagen, Inc. |
Custom recombinant polyclonal proteins and methods of use thereof
|
|
WO2026033259A1
(en)
|
2024-08-05 |
2026-02-12 |
Lys Therapeutics |
Antibodies for treating neurological and neurovascular disorders
|
|
WO2026072990A1
(en)
|
2024-09-27 |
2026-04-02 |
Abcuro, Inc. |
Methods of treating t-cell large granular lymphocytic leukemia
|
|
WO2026082894A1
(en)
|
2024-10-17 |
2026-04-23 |
Sanofi |
Ceacam5 antibody-drug conjugate for use in cancer therapy
|