HRP20180962T1 - Liječenje bolesti zgrušavanja primjenom rekombinantnog vwf - Google Patents
Liječenje bolesti zgrušavanja primjenom rekombinantnog vwfInfo
- Publication number
- HRP20180962T1 HRP20180962T1 HRP20180962TT HRP20180962T HRP20180962T1 HR P20180962 T1 HRP20180962 T1 HR P20180962T1 HR P20180962T T HRP20180962T T HR P20180962TT HR P20180962 T HRP20180962 T HR P20180962T HR P20180962 T1 HRP20180962 T1 HR P20180962T1
- Authority
- HR
- Croatia
- Prior art keywords
- administration
- treatment
- recombinant vwf
- coagulation disease
- coagulation
- Prior art date
Links
- 230000015271 coagulation Effects 0.000 title 1
- 238000005345 coagulation Methods 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161495884P | 2011-06-10 | 2011-06-10 | |
| US201161511901P | 2011-07-26 | 2011-07-26 | |
| US201161523790P | 2011-08-15 | 2011-08-15 | |
| PCT/US2012/041957 WO2012171031A1 (en) | 2011-06-10 | 2012-06-11 | Treatment of coagulation disease by administration of recombinant vwf |
| EP12728919.7A EP2717905B1 (en) | 2011-06-10 | 2012-06-11 | Treatment of coagulation disease by administration of recombinant vwf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20180962T1 true HRP20180962T1 (hr) | 2018-10-19 |
Family
ID=46321496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20180962TT HRP20180962T1 (hr) | 2011-06-10 | 2018-06-26 | Liječenje bolesti zgrušavanja primjenom rekombinantnog vwf |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US9272021B2 (hr) |
| EP (3) | EP3858375B1 (hr) |
| JP (3) | JP6347468B2 (hr) |
| KR (3) | KR101969515B1 (hr) |
| CN (3) | CN103732244A (hr) |
| AR (1) | AR086904A1 (hr) |
| AU (5) | AU2012267458A1 (hr) |
| BR (1) | BR112013031795A2 (hr) |
| CA (1) | CA2838845C (hr) |
| DK (3) | DK2717905T3 (hr) |
| ES (2) | ES2860450T3 (hr) |
| FI (1) | FI3858375T3 (hr) |
| HK (1) | HK1257436A1 (hr) |
| HR (1) | HRP20180962T1 (hr) |
| HU (1) | HUE039317T2 (hr) |
| LT (1) | LT2717905T (hr) |
| MX (2) | MX350582B (hr) |
| PL (2) | PL2717905T3 (hr) |
| PT (2) | PT2717905T (hr) |
| RU (2) | RU2680402C2 (hr) |
| SG (2) | SG10202002591QA (hr) |
| SI (1) | SI2717905T1 (hr) |
| TR (1) | TR201808823T4 (hr) |
| WO (1) | WO2012171031A1 (hr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012171031A1 (en) * | 2011-06-10 | 2012-12-13 | Baxter International Inc. | Treatment of coagulation disease by administration of recombinant vwf |
| CN102776260B (zh) * | 2012-07-26 | 2015-04-29 | 上海泰龙生物医药科技有限公司 | 一种高效表达重组人凝血八因子的方法 |
| ES2657291T3 (es) * | 2013-04-22 | 2018-03-02 | Csl Ltd. | Un complejo covalente de factor de von Willebrand y factor VIII asociado por un puente disulfuro |
| WO2017180807A1 (en) | 2016-04-15 | 2017-10-19 | Baxalta Incorporated | Method and apparatus for providing a pharmacokinetic drug dosing regiment |
| NL2013007B1 (en) | 2014-06-16 | 2016-07-05 | Ablynx Nv | Methods of treating TTP with immunoglobulin single variable domains and uses thereof. |
| FR3034669B1 (fr) | 2015-04-07 | 2020-02-14 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Nouvelle utilisation du facteur von willebrand |
| US10896749B2 (en) | 2017-01-27 | 2021-01-19 | Shire Human Genetic Therapies, Inc. | Drug monitoring tool |
| BR112020000322A2 (pt) * | 2017-07-07 | 2020-07-14 | Baxalta Incorporated | uso de fator de von willebrand recombinante (rvwf) |
| EP3648788A1 (en) * | 2017-07-07 | 2020-05-13 | Baxalta Incorporated | Treatment of gastrointestinal bleeding in patients with severe von willebrand disease by administration of recombinant vwf |
| SG11202009213TA (en) * | 2018-03-21 | 2020-10-29 | Baxalta Inc | Separation of vwf and vwf propeptide by chromatographic methods |
| MX2021009114A (es) * | 2019-02-01 | 2021-10-13 | Takeda Pharmaceuticals Co | Métodos de tratamiento profiláctico que usan factor de von willebrand recombinante (rvwf). |
| JP2022547556A (ja) | 2019-09-11 | 2022-11-14 | 武田薬品工業株式会社 | フォン・ヴィレブランド因子と補体ｃ１ｑの複合体に関連する治療法 |
| AU2021216945A1 (en) | 2020-02-04 | 2022-09-01 | Takeda Pharmaceutical Company Limited | Treatment of menorrhagia in patients with severe von Willebrand Disease by administration of recombinant VWF |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US4638028A (en) | 1985-04-08 | 1987-01-20 | Goodyear Tire & Rubber Company | Rubber polymerases and methods for their production and use |
| WO1986006096A1 (en) | 1985-04-11 | 1986-10-23 | The Children's Medical Center Corporation | Von willebrand factor |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| SE504074C2 (sv) * | 1993-07-05 | 1996-11-04 | Pharmacia Ab | Proteinberedning för subkutan, intramuskulär eller intradermal administrering |
| DE4435485C1 (de) * | 1994-10-04 | 1996-03-21 | Immuno Ag | Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor |
| AT403764B (de) * | 1996-03-15 | 1998-05-25 | Immuno Ag | Stabiler faktor viii/vwf-komplex |
| AT406373B (de) * | 1997-02-27 | 2000-04-25 | Immuno Ag | Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie |
| AT405403B (de) * | 1997-02-27 | 1999-08-25 | Immuno Ag | Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie |
| US6531577B1 (en) | 1997-12-15 | 2003-03-11 | Hemasure Denmark A/S | von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations |
| US6864403B1 (en) | 1998-10-15 | 2005-03-08 | E. I. Du Pont De Nemours And Company | Plant protein disulfide isomerases |
| US20040014657A1 (en) * | 2001-11-05 | 2004-01-22 | Jan Ohrstrom | Use of blood coagulation factor XIII for treating haemophilia A |
| WO2005012354A1 (en) * | 2003-07-31 | 2005-02-10 | Zlb Behring Gmbh | Method for extending the half-life of fviii |
| EP1593388A1 (en) | 2004-05-05 | 2005-11-09 | ZLB Behring GmbH | Therapeutic plasma protein-concentrates containing von willebrand factor as high molecular weight multimers |
| US20060094104A1 (en) | 2004-10-29 | 2006-05-04 | Leopold Grillberger | Animal protein-free media for cultivation of cells |
| EP1835938B1 (en) * | 2004-12-27 | 2013-08-07 | Baxter International Inc. | Polymer-von willebrand factor-conjugates |
| ES2790887T3 (es) | 2006-01-04 | 2020-10-29 | Baxalta Inc | Medio de cultivo celular sin oligopéptidos |
| EP2486936A1 (en) * | 2007-06-13 | 2012-08-15 | CSL Behring GmbH | A composition comprising VWF and FVIII preparations for use in treating of bleeding disorders |
| EP2222329A1 (en) | 2007-11-09 | 2010-09-01 | Baxter International Inc. | Modified recombinant factor viii and von willebrand factor and methods of use |
| JP2009127455A (ja) | 2007-11-20 | 2009-06-11 | Bando Kiko Co Ltd | 往復動エンジン |
| TWI515006B (zh) * | 2007-12-28 | 2016-01-01 | 巴克斯特國際公司 | 重組ｖｗｆ調配物 |
| ES2298096B1 (es) * | 2008-01-08 | 2009-01-01 | Grifols, S.A. | Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos. |
| US8575104B2 (en) * | 2008-06-24 | 2013-11-05 | Csl Behring Gmbh | Factor VIII, von willebrand factor or complexes thereof with prolonged in vivo half-life |
| CN102387784B (zh) * | 2008-10-21 | 2014-04-02 | 巴克斯特国际公司 | 冻干的重组vwf配方 |
| JP2013500743A (ja) * | 2009-08-04 | 2013-01-10 | バクスター・インターナショナル・インコーポレイテッド | Ｆｖｉｉｉおよびｖｗｆがノックアウトされた遺伝子導入マウス−血友病ａモデル |
| AU2011274467B2 (en) * | 2010-07-08 | 2015-01-15 | Takeda Pharmaceutical Company Limited | Method of producing recombinant high molecular weight vWF in cell culture |
| US20120006800A1 (en) | 2010-07-09 | 2012-01-12 | Illinois Tool Works Inc. | Weld bead feature communication systems and devices |
| WO2012171031A1 (en) * | 2011-06-10 | 2012-12-13 | Baxter International Inc. | Treatment of coagulation disease by administration of recombinant vwf |
-
2012
- 2012-06-11 WO PCT/US2012/041957 patent/WO2012171031A1/en active Application Filing
- 2012-06-11 KR KR1020147000709A patent/KR101969515B1/ko active IP Right Grant
- 2012-06-11 CN CN201280038870.7A patent/CN103732244A/zh active Pending
- 2012-06-11 ES ES18173179T patent/ES2860450T3/es active Active
- 2012-06-11 SG SG10202002591QA patent/SG10202002591QA/en unknown
- 2012-06-11 CN CN201611071108.5A patent/CN107412743B/zh active Active
- 2012-06-11 FI FIEP20216368.9T patent/FI3858375T3/fi active
- 2012-06-11 RU RU2017102679A patent/RU2680402C2/ru active
- 2012-06-11 CA CA2838845A patent/CA2838845C/en active Active
- 2012-06-11 PT PT127289197T patent/PT2717905T/pt unknown
- 2012-06-11 MX MX2013014543A patent/MX350582B/es active IP Right Grant
- 2012-06-11 PL PL12728919T patent/PL2717905T3/pl unknown
- 2012-06-11 PT PT181731795T patent/PT3412305T/pt unknown
- 2012-06-11 AR ARP120102073A patent/AR086904A1/es not_active Application Discontinuation
- 2012-06-11 LT LTEP12728919.7T patent/LT2717905T/lt unknown
- 2012-06-11 JP JP2014514934A patent/JP6347468B2/ja active Active
- 2012-06-11 KR KR1020207020667A patent/KR102319868B1/ko active IP Right Grant
- 2012-06-11 CN CN201810079423.5A patent/CN108210889A/zh active Pending
- 2012-06-11 DK DK12728919.7T patent/DK2717905T3/en active
- 2012-06-11 EP EP20216368.9A patent/EP3858375B1/en active Active
- 2012-06-11 KR KR1020197010327A patent/KR20190041032A/ko not_active IP Right Cessation
- 2012-06-11 RU RU2014100107A patent/RU2628537C2/ru active
- 2012-06-11 EP EP18173179.5A patent/EP3412305B1/en active Active
- 2012-06-11 AU AU2012267458A patent/AU2012267458A1/en not_active Abandoned
- 2012-06-11 EP EP12728919.7A patent/EP2717905B1/en active Active
- 2012-06-11 BR BR112013031795A patent/BR112013031795A2/pt not_active Application Discontinuation
- 2012-06-11 ES ES12728919.7T patent/ES2682249T3/es active Active
- 2012-06-11 TR TR2018/08823T patent/TR201808823T4/tr unknown
- 2012-06-11 SG SG10201604684WA patent/SG10201604684WA/en unknown
- 2012-06-11 US US13/493,926 patent/US9272021B2/en active Active
- 2012-06-11 DK DK20216368.9T patent/DK3858375T3/da active
- 2012-06-11 PL PL18173179T patent/PL3412305T3/pl unknown
- 2012-06-11 DK DK18173179.5T patent/DK3412305T3/da active
- 2012-06-11 SI SI201231321T patent/SI2717905T1/sl unknown
- 2012-06-11 HU HUE12728919A patent/HUE039317T2/hu unknown
-
2013
- 2013-12-10 MX MX2020000083A patent/MX2020000083A/es unknown
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2015
- 2015-12-30 US US14/985,212 patent/US20160184403A1/en active Pending
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2016
- 2016-04-13 AU AU2016202299A patent/AU2016202299B2/en active Active
- 2016-07-12 JP JP2016137381A patent/JP6527114B2/ja active Active
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2017
- 2017-07-20 AU AU2017206235A patent/AU2017206235B2/en active Active
-
2018
- 2018-06-26 HR HRP20180962TT patent/HRP20180962T1/hr unknown
- 2018-12-27 HK HK18116648.2A patent/HK1257436A1/zh unknown
- 2018-12-28 JP JP2018246475A patent/JP2019048892A/ja active Pending
-
2020
- 2020-01-02 AU AU2020200026A patent/AU2020200026A1/en not_active Abandoned
-
2022
- 2022-03-04 AU AU2022201518A patent/AU2022201518A1/en active Pending
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