|
WO2010077634A1
(en)
|
2008-12-09 |
2010-07-08 |
Genentech, Inc. |
Anti-pd-l1 antibodies and their use to enhance t-cell function
|
|
EP2445932B1
(en)
|
2009-06-26 |
2018-02-28 |
Soricimed Biopharma Inc. |
Soricidin derived peptides and methods for the detection of trpv-6 cancers and drug delivery
|
|
US9416132B2
(en)
|
2011-07-21 |
2016-08-16 |
Tolero Pharmaceuticals, Inc. |
Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors
|
|
JOP20200236A1
(ar)
|
2012-09-21 |
2017-06-16 |
Regeneron Pharma |
الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
|
|
TWI635098B
(zh)
|
2013-02-01 |
2018-09-11 |
再生元醫藥公司 |
含嵌合恆定區之抗體
|
|
AR095196A1
(es)
|
2013-03-15 |
2015-09-30 |
Regeneron Pharma |
Medio de cultivo celular libre de suero
|
|
HRP20210122T1
(hr)
|
2013-05-02 |
2021-04-16 |
Anaptysbio, Inc. |
Protutijela usmjerena protiv programirane smrti-1 (pd-1)
|
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
|
EP3757130A1
(en)
|
2013-09-26 |
2020-12-30 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
PE20160953A1
(es)
|
2013-12-12 |
2016-09-26 |
Shanghai hengrui pharmaceutical co ltd |
Anticuerpo pd-1, fragmento de union al antigeno de este y uso medico de este
|
|
TWI680138B
(zh)
*
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗ｐｄ-ｌ１之人類抗體
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對ｐｄ-１的人類抗體
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
US10519237B2
(en)
|
2014-03-12 |
2019-12-31 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
US10618963B2
(en)
|
2014-03-12 |
2020-04-14 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
US9394365B1
(en)
|
2014-03-12 |
2016-07-19 |
Yeda Research And Development Co., Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease
|
|
ES3040431T3
(en)
|
2014-03-12 |
2025-10-31 |
Yeda Res & Dev |
Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
|
|
WO2017042633A2
(en)
*
|
2015-09-10 |
2017-03-16 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
|
|
ME03558B
(me)
|
2014-03-14 |
2020-07-20 |
Novartis Ag |
Molekuli anti-lag-3 antiтela i njihove upotrebe
|
|
TWI701042B
(zh)
|
2014-03-19 |
2020-08-11 |
美商再生元醫藥公司 |
用於腫瘤治療之方法及抗體組成物
|
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
CA2957258C
(en)
|
2014-08-05 |
2023-11-07 |
MabQuest SA |
Immunological reagents
|
|
US9982052B2
(en)
|
2014-08-05 |
2018-05-29 |
MabQuest, SA |
Immunological reagents
|
|
KR20170060042A
(ko)
|
2014-09-13 |
2017-05-31 |
노파르티스 아게 |
Alk 억제제의 조합 요법
|
|
SI3221359T1
(sl)
|
2014-11-17 |
2020-08-31 |
Regeneron Pharmaceuticals, Inc. |
Metode zravljenja tumorja z uporabo bispecifičnega protitelesa CD3XCD20
|
|
JP6891112B2
(ja)
*
|
2014-11-20 |
2021-06-18 |
プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ |
免疫チェックポイントの調節因子を評価するためのシステム及び方法
|
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗ｐｄ－１抗體類和使用彼等之方法
|
|
JP6936784B2
(ja)
|
2015-03-30 |
2021-09-22 |
エスティーキューブ，インコーポレイテッド |
グリコシル化ｐｄ−ｌ１に特異的な抗体およびその使用方法
|
|
EP3277725B1
(en)
|
2015-03-30 |
2020-11-25 |
Regeneron Pharmaceuticals, Inc. |
Heavy chain constant regions with reduced binding to fc gamma receptors
|
|
US11933786B2
(en)
|
2015-03-30 |
2024-03-19 |
Stcube, Inc. |
Antibodies specific to glycosylated PD-L1 and methods of use thereof
|
|
JP6901400B2
(ja)
|
2015-04-03 |
2021-07-14 |
ゾーマ テクノロジー リミテッド |
ＴＧＦ−β及びＰＤ−１の阻害物質を使用する癌の治療法
|
|
KR20180029201A
(ko)
|
2015-05-18 |
2018-03-20 |
티씨알2 테라퓨틱스 인크. |
융합 단백질을 이용하는 tcr 리프로그래밍을 위한 조성물 및 방법
|
|
JP6510075B2
(ja)
|
2015-05-18 |
2019-05-08 |
トレロ ファーマシューティカルズ， インコーポレイテッド |
バイオアベイラビリティが高いアルボシジブプロドラッグ
|
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
|
TWI870335B
(zh)
|
2015-06-12 |
2025-01-21 |
美商宏觀基因股份有限公司 |
變異的嵌合4d5抗體及其與抗pd-1抗體聯合用於治療癌症的應用
|
|
EP3322732A2
(en)
|
2015-07-13 |
2018-05-23 |
Cytomx Therapeutics Inc. |
Anti-pd-1 antibodies, activatable anti-pd-1 antibodies, and methods of use thereof
|
|
HK1248115A1
(zh)
|
2015-07-16 |
2018-10-12 |
Bioxcel Therapeutics, Inc. |
一种使用免疫调节治疗癌症的新颖方法
|
|
CN116333138A
(zh)
|
2015-07-30 |
2023-06-27 |
宏观基因有限公司 |
Pd-1结合分子和其使用方法
|
|
TW202440903A
(zh)
|
2015-08-04 |
2024-10-16 |
美商再生元醫藥公司 |
補充牛磺酸之細胞培養基及用法（一）
|
|
EP3331901A1
(en)
|
2015-08-07 |
2018-06-13 |
Pieris Pharmaceuticals GmbH |
Novel fusion polypeptide specific for lag-3 and pd-1
|
|
FI3334763T3
(fi)
*
|
2015-08-11 |
2024-10-30 |
Wuxi Biologics Ireland Ltd |
Uusia pd-l1-vasta-aineita
|
|
AR105654A1
(es)
*
|
2015-08-24 |
2017-10-25 |
Lilly Co Eli |
Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
|
|
HK1257840A1
(zh)
*
|
2015-09-01 |
2019-11-01 |
Agenus Inc. |
抗-pd-1抗体及其使用方法
|
|
CN108290951B
(zh)
|
2015-09-23 |
2022-04-01 |
瑞泽恩制药公司 |
优化抗cd3双特异性抗体和其用途
|
|
KR20180063885A
(ko)
*
|
2015-09-24 |
2018-06-12 |
더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 |
전이 감소를 위한 방법 및 조성물
|
|
AU2016332725A1
(en)
|
2015-09-29 |
2018-03-22 |
Celgene Corporation |
PD-1 binding proteins and methods of use thereof
|
|
US10981991B2
(en)
|
2015-09-29 |
2021-04-20 |
Shanghai Zhangjiang Biotechnology Co., Ltd. |
PD-1 antibodies and uses thereof
|
|
US12030942B2
(en)
|
2015-10-02 |
2024-07-09 |
Les Laboratoires Servier |
Anti-PD-1 antibodies and compositions
|
|
US11034765B2
(en)
*
|
2015-10-02 |
2021-06-15 |
Symphogen A/S |
Anti-PD-1 antibodies and compositions
|
|
PE20180773A1
(es)
|
2015-10-02 |
2018-05-07 |
Hoffmann La Roche |
Anticuerpos biespecificos para pd1 y tim3
|
|
IL258521B2
(en)
|
2015-10-08 |
2024-01-01 |
Macrogenics Inc |
Combination therapy for the treatment of cancer
|
|
TWI756187B
(zh)
|
2015-10-09 |
2022-03-01 |
美商再生元醫藥公司 |
抗ｌａｇ３抗體及其用途
|
|
SI3370768T1
(sl)
|
2015-11-03 |
2022-04-29 |
Janssen Biotech, Inc. |
Protitelesa, ki se specifično vežejo na PD-1, in njihove uporabe
|
|
CN106699889A
(zh)
*
|
2015-11-18 |
2017-05-24 |
礼进生物医药科技（上海）有限公司 |
抗pd-1抗体及其治疗用途
|
|
SG10201911035QA
(en)
|
2015-11-18 |
2020-01-30 |
Merck Sharp & Dohme |
Pd1 and/or lag3 binders
|
|
EP3383412A4
(en)
|
2015-12-02 |
2019-06-05 |
Stcube, Inc. |
SPECIFIC ANTIBODIES TO GLYCOSED PD-1 AND METHOD OF USE THEREOF
|
|
TW202208440A
(zh)
|
2015-12-14 |
2022-03-01 |
美商宏觀基因股份有限公司 |
對於pd-1和ctla-4具有免疫反應性的雙特異性分子及其使用方法
|
|
US10392442B2
(en)
|
2015-12-17 |
2019-08-27 |
Bristol-Myers Squibb Company |
Use of anti-PD-1 antibody in combination with anti-CD27 antibody in cancer treatment
|
|
SI3394103T1
(sl)
*
|
2015-12-22 |
2023-10-30 |
Regeneron Pharmaceuticals, Inc. |
Kombinacija protiteles proti-PD-1 in bispecifičnih protiteles proti-CD20/proti-CD3 za zdravljenje raka
|
|
CN105669864B
(zh)
*
|
2015-12-23 |
2018-10-16 |
杭州尚健生物技术有限公司 |
抗人程序性死亡受体1抗体及其制备方法和用途
|
|
JP7026047B2
(ja)
*
|
2016-01-21 |
2022-02-25 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
免疫調節剤を併用するがんの治療
|
|
CA3012075A1
(en)
*
|
2016-01-22 |
2017-07-27 |
MabQuest SA |
Immunological reagents
|
|
US11214617B2
(en)
|
2016-01-22 |
2022-01-04 |
MabQuest SA |
Immunological reagents
|
|
EP3408671B1
(en)
|
2016-01-25 |
2023-11-01 |
F. Hoffmann-La Roche AG |
Methods for assaying t-cell dependent bispecific antibodies
|
|
SG11201805941WA
(en)
|
2016-02-17 |
2018-09-27 |
Novartis Ag |
Tgfbeta 2 antibodies
|
|
IL261188B
(en)
|
2016-03-04 |
2022-08-01 |
Jn Biosciences Llc |
An anti-tigit antibody that binds to the tigit polypeptide on one or more amino acid residues
|
|
EP3432924A1
(en)
*
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
US10894823B2
(en)
*
|
2016-03-24 |
2021-01-19 |
Gensun Biopharma Inc. |
Trispecific inhibitors for cancer treatment
|
|
US11542332B2
(en)
|
2016-03-26 |
2023-01-03 |
Bioatla, Inc. |
Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof
|
|
CA3039910A1
(en)
*
|
2016-03-28 |
2017-10-05 |
The Regents Of The University Of California |
Anti-ryk antibodies and methods of using the same
|
|
KR20180130541A
(ko)
|
2016-03-29 |
2018-12-07 |
주식회사 에스티큐브앤컴퍼니 |
글리코실화된 면역체크포인트 단백질에 특이적으로 결합하는 항체를 선택하는 방법
|
|
JP7241541B2
(ja)
|
2016-03-29 |
2023-03-17 |
エスティーキューブ，インコーポレイテッド |
グリコシル化ｐｄ－ｌ１に特異的な二重機能抗体およびその使用方法
|
|
CA3022961A1
(en)
*
|
2016-05-02 |
2017-11-09 |
Tetragenetics, Inc. |
Anti-kv1.3 antibodies, and methods of production and use thereof
|
|
TW202408578A
(zh)
*
|
2016-05-13 |
2024-03-01 |
美商再生元醫藥公司 |
藉由投予pd-1抑制劑治療皮膚癌之方法
|
|
BR112018074619A2
(pt)
|
2016-06-02 |
2019-03-06 |
Bristol Myers Squibb Co |
uso de um anticorpo anti-pd-1 em combinação com um anticorpo anti-cd30 em tratamento com câncer
|
|
FI3463457T3
(fi)
|
2016-06-02 |
2023-09-12 |
Bristol Myers Squibb Co |
Pd-1-esto nivolumabilla refraktaarinen hodgkinin lymfoomassa
|
|
KR20250107295A
(ko)
|
2016-06-03 |
2025-07-11 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법에 사용하기 위한 항-pd-1 항체
|
|
KR102702675B1
(ko)
|
2016-06-03 |
2024-09-05 |
브리스톨-마이어스 스큅 컴퍼니 |
결장직장암을 갖는 환자의 치료에서의 항-pd-1 항체의 용도
|
|
JP2019517498A
(ja)
|
2016-06-03 |
2019-06-24 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
再発性小細胞肺癌の処置方法において使用するための抗ｐｄ−１抗体
|
|
MX2018014950A
(es)
*
|
2016-06-07 |
2019-04-25 |
Macrogenics Inc |
Terapia de combinacion.
|
|
WO2017214182A1
(en)
*
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Fully human antibody targeting pdi for cancer immunotherapy
|
|
KR20190017767A
(ko)
*
|
2016-06-10 |
2019-02-20 |
노파르티스 아게 |
C-raf 억제제의 치료적 용도
|
|
KR102495601B1
(ko)
|
2016-06-10 |
2023-02-06 |
리제너론 파마슈티칼스 인코포레이티드 |
항-gitr 항체 및 그것의 사용
|
|
CA3029813A1
(en)
|
2016-06-13 |
2017-12-21 |
Torque Therapeutics, Inc. |
Methods and compositions for promoting immune cell function
|
|
BR112018076260A2
(pt)
|
2016-06-20 |
2019-03-26 |
Kymab Limited |
anticorpo ou fragmento do mesmo que se liga especificamente a hpd-l1, anticorpo biespecífico ou proteína de fusão, uso de um anticorpo ou fragmento, método, composição farmacêutica, método de modulação, método de inibição, método de tratamento, ácido nucleico, vetor, hospedeiro e imunocitocina
|
|
US9567399B1
(en)
|
2016-06-20 |
2017-02-14 |
Kymab Limited |
Antibodies and immunocytokines
|
|
GB2602935B
(en)
*
|
2016-07-18 |
2022-10-12 |
Harvard College |
Human lymphoid tissue-on-chip
|
|
CN109715666B
(zh)
|
2016-07-20 |
2023-02-21 |
斯特库比股份有限公司 |
癌症治疗方法和使用结合糖基化pd-l1的抗体的组合的疗法
|
|
NL2017267B1
(en)
|
2016-07-29 |
2018-02-01 |
Aduro Biotech Holdings Europe B V |
Anti-pd-1 antibodies
|
|
WO2018026953A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
WO2018026248A1
(ko)
*
|
2016-08-05 |
2018-02-08 |
주식회사 와이바이오로직스 |
프로그램화된 세포 사멸 단백질(pd-1)에 대한 신규 항체 및 이의 용도
|
|
UA125395C2
(uk)
*
|
2016-08-05 |
2022-03-02 |
І-Байолоджікс Інк. |
Антитіло проти білка-1 запрограмованої клітинної смерті (pd-1) і його застосування
|
|
CN116640214A
(zh)
|
2016-08-09 |
2023-08-25 |
科马布有限公司 |
分离抗体及其应用
|
|
EP4653462A2
(en)
|
2016-08-22 |
2025-11-26 |
Arbutus Biopharma Corporation |
Anti-pd-1 antibodies, or fragments thereof, for treating hepatitis b
|
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
|
CN106967172B
(zh)
|
2016-08-23 |
2019-01-08 |
康方药业有限公司 |
抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途
|
|
CN106977602B
(zh)
|
2016-08-23 |
2018-09-25 |
中山康方生物医药有限公司 |
一种抗pd1单克隆抗体、其药物组合物及其用途
|
|
WO2018039499A1
(en)
|
2016-08-24 |
2018-03-01 |
Regeneron Pharmaceuticals, Inc. |
Host cell protein modification
|
|
US10751414B2
(en)
|
2016-09-19 |
2020-08-25 |
Celgene Corporation |
Methods of treating psoriasis using PD-1 binding antibodies
|
|
JP2019534859A
(ja)
|
2016-09-19 |
2019-12-05 |
セルジーン コーポレイション |
Ｐｄ−１結合タンパク質を使用して白斑を治療する方法
|
|
IL265605B2
(en)
|
2016-09-29 |
2024-06-01 |
Beijing Hanmi Pharmaceutical Co Ltd |
Heterodimeric immunoglobulin constructs, pharmaceutical composition comprising the same, use and preparation methods thereof
|
|
IL302917A
(en)
|
2016-10-07 |
2023-07-01 |
Tcr2 Therapeutics Inc |
Compositions and methods for t-cell receptors reprogramming using fusion proteins
|
|
EP4491237A3
(en)
|
2016-10-28 |
2025-03-26 |
Bristol-Myers Squibb Company |
Methods of treating urothelial carcinoma using an anti-pd-1 antibody
|
|
EP3666794A1
(en)
|
2016-11-01 |
2020-06-17 |
AnaptysBio, Inc. |
Antibodies directed against programmed death- 1 (pd-1)
|
|
TWI781120B
(zh)
|
2016-11-02 |
2022-10-21 |
美商永斯醫療股份有限公司 |
Ｐｄ-１之抗體及其用途
|
|
KR102584340B1
(ko)
|
2016-11-03 |
2023-10-10 |
브리스톨-마이어스 스큅 컴퍼니 |
활성화가능한 항-ctla-4 항체 및 그의 용도
|
|
US11779604B2
(en)
|
2016-11-03 |
2023-10-10 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses and methods
|
|
AU2017356860A1
(en)
*
|
2016-11-08 |
2019-05-16 |
Qilu Puget Sound Biotherapeutics Corporation |
Anti-PD1 and anti-CTLA4 antibodies
|
|
AU2017359813B2
(en)
|
2016-11-18 |
2024-12-05 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
Anti-PD-1/anti-HER2 natural antibody structure-like bispecific antibody of heterodimeric form and preparation thereof
|
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
ES2991086T3
(es)
*
|
2016-11-18 |
2024-12-02 |
Servier Lab |
Anticuerpos y composiciones anti-PD-1
|
|
JP7291396B2
(ja)
|
2016-11-22 |
2023-06-15 |
ティーシーアール２ セラピューティクス インク． |
融合タンパク質を用いたｔｃｒの再プログラミングのための組成物及び方法
|
|
WO2018098352A2
(en)
|
2016-11-22 |
2018-05-31 |
Jun Oishi |
Targeting kras induced immune checkpoint expression
|
|
EP3548515A1
(en)
*
|
2016-12-01 |
2019-10-09 |
Regeneron Pharmaceuticals, Inc. |
Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging
|
|
EP3551225A1
(en)
|
2016-12-07 |
2019-10-16 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
CN110168105B
(zh)
|
2016-12-09 |
2024-05-24 |
瑞泽恩制药公司 |
用于对t细胞受体进行测序的系统和方法及其用途
|
|
EP3559044A4
(en)
*
|
2016-12-23 |
2020-12-02 |
REMD Biotherapeutics, Inc. |
IMMUNOTHERAPY USING ANTIBODIES THAT BINDING PROGRAMMED CELL DEATH 1 (PD-1)
|
|
CN106674209B
(zh)
*
|
2016-12-23 |
2020-03-06 |
深圳先进技术研究院 |
程序性死亡受体1基因抑制剂及其制备方法与应用
|
|
CN108203464B
(zh)
*
|
2016-12-25 |
2021-07-20 |
南京金斯瑞生物科技有限公司 |
高亲和力、高特异性、多抗原识别表位的具有更高功能性的抗人pd-1抗体
|
|
CN113480530A
(zh)
|
2016-12-26 |
2021-10-08 |
阿里根公司 |
芳香烃受体调节剂
|
|
CN109071656B
(zh)
|
2017-01-05 |
2021-05-18 |
璟尚生物制药公司 |
检查点调节物拮抗剂
|
|
CN110382545A
(zh)
|
2017-01-09 |
2019-10-25 |
泰萨罗公司 |
用抗pd-1抗体治疗癌症的方法
|
|
WO2018134279A1
(en)
|
2017-01-18 |
2018-07-26 |
Pieris Pharmaceuticals Gmbh |
Novel fusion polypeptides specific for lag-3 and pd-1
|
|
TW202506185A
(zh)
*
|
2017-01-20 |
2025-02-16 |
法商賽諾菲公司 |
抗TGF-β抗體及其用途
|
|
AR110755A1
(es)
|
2017-01-20 |
2019-05-02 |
Genzyme Corp |
Anticuerpos dirigidos a hueso
|
|
EP3570870A1
(en)
|
2017-01-20 |
2019-11-27 |
Novartis AG |
Combination therapy for the treatment of cancer
|
|
AR110904A1
(es)
*
|
2017-01-20 |
2019-05-15 |
Sanofi Sa |
ANTICUERPOS ANTI-TGF-b Y SU USO
|
|
EA201991729A1
(ru)
|
2017-01-20 |
2019-12-30 |
Санофи |
Антитела к tgf-бета и их применение
|
|
AU2018209556C1
(en)
|
2017-01-20 |
2020-10-15 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
Anti-PD-1 antibodies and uses thereof
|
|
BR112019016336A2
(pt)
|
2017-02-10 |
2020-03-31 |
Regeneron Pharmaceuticals, Inc. |
Conjugado de anticorpo radiorrotulado, método para imageamento de um tecido que expressa lag3 e para tratar um tumor, e, composto.
|
|
CA3051986A1
(en)
|
2017-02-10 |
2018-08-16 |
Novartis Ag |
1-(4-amino-5-bromo-6-(1 h-pyrazol-1-yl)pyrimidin-2-yl)-1 h-pyrazol-4-ol and use thereof in the treatment of cancer
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
US11292842B2
(en)
*
|
2017-02-21 |
2022-04-05 |
Regeneron Pharmaceuticals, Inc. |
Anti-PD-1 antibodies for treatment of lung cancer
|
|
EP3585431A4
(en)
|
2017-02-24 |
2020-12-16 |
MacroGenics, Inc. |
BISPECIFIC BINDING MOLECULES CAPABLE OF BINDING TO CD137 AND TUMOR ANTIGENS, AND THEIR USES
|
|
EP3589308A1
(en)
|
2017-02-28 |
2020-01-08 |
Sanofi |
Therapeutic rna
|
|
US11161905B2
(en)
|
2017-03-04 |
2021-11-02 |
Xiangtan Tenghua Bioscience |
Recombinant antibodies to programmed death 1 (PD-1) and uses thereof
|
|
JP7165717B2
(ja)
|
2017-03-15 |
2022-11-04 |
パンディオン・オペレーションズ・インコーポレイテッド |
標的免疫寛容
|
|
US20180289802A1
(en)
*
|
2017-03-29 |
2018-10-11 |
Celgene Corporation |
Formulations comprising pd-1 binding proteins and methods of making thereof
|
|
KR20250036268A
(ko)
|
2017-03-31 |
2025-03-13 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
MX2019011748A
(es)
*
|
2017-04-01 |
2020-01-23 |
Beijing hanmi pharm co ltd |
Anticuerpo biespecífico heterodimérico tipo estructura de anticuerpo natural anti-pd-l1/anti-pd-1 y preparación del mismo.
|
|
PT3606946T
(pt)
*
|
2017-04-03 |
2022-10-17 |
Hoffmann La Roche |
Imunoconjugados de um anticorpo anti-pd-1 com uma il-2 mutante ou com il-15
|
|
WO2018187227A1
(en)
|
2017-04-03 |
2018-10-11 |
Concologie, Inc. |
Methods for treating cancer using ps-targeting antibodies with immuno-oncology agents
|
|
CN110621698B
(zh)
|
2017-04-05 |
2024-04-12 |
法国施维雅药厂 |
靶向pd-1、tim-3及lag-3的组合疗法
|
|
CN116375876A
(zh)
|
2017-04-05 |
2023-07-04 |
豪夫迈·罗氏有限公司 |
特异性结合pd1和lag3的双特异性抗体
|
|
US11603407B2
(en)
*
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
AR111760A1
(es)
|
2017-05-19 |
2019-08-14 |
Novartis Ag |
Compuestos y composiciones para el tratamiento de tumores sólidos mediante administración intratumoral
|
|
WO2018217659A1
(en)
*
|
2017-05-22 |
2018-11-29 |
Oncoimmune, Inc. |
Methods of use of soluble cd24 for treating immune related adverse events in cancer therapies
|
|
MX2019013517A
(es)
|
2017-05-24 |
2020-08-17 |
Pandion Operations Inc |
Inmunotolerancia dirigida.
|
|
BR112019018759A2
(pt)
|
2017-05-30 |
2020-05-05 |
Bristol-Myers Squibb Company |
composições compreendendo uma combinação de um anticorpo anti-lag-3, um inibidor da via pd-1, e um agente imunoterápico
|
|
BR112019021847A2
(pt)
|
2017-05-30 |
2020-06-02 |
Bristol-Myers Squibb Company |
Composições compreendendo um anticorpo anti-lag-3 ou um anticorpo anti-lag-3 e um anticorpo anti-pd-1 ou anti-pd-l1
|
|
HUE065242T2
(hu)
|
2017-05-30 |
2024-05-28 |
Bristol Myers Squibb Co |
LAG-3-pozitív tumorok kezelése
|
|
JOP20190279A1
(ar)
|
2017-05-31 |
2019-11-28 |
Novartis Ag |
الصور البلورية من 5-برومو -2، 6-داي (1h-بيرازول -1-يل) بيريميدين -4- أمين وأملاح جديدة
|
|
US11566073B2
(en)
|
2017-06-01 |
2023-01-31 |
Bristol-Myers Squibb Company |
Methods of treating a tumor using an anti-PD-1 antibody
|
|
MX2019014577A
(es)
|
2017-06-05 |
2020-07-29 |
Janssen Biotech Inc |
Anticuerpos que se unen especificamente a pd-1 y metodos de uso.
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
GB201709808D0
(en)
|
2017-06-20 |
2017-08-02 |
Kymab Ltd |
Antibodies
|
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
EP3641812A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
|
WO2018235056A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Il-1beta binding antibodies for use in treating cancer
|
|
AU2018287519B2
(en)
|
2017-06-22 |
2021-07-22 |
Novartis Ag |
IL-1beta binding antibodies for use in treating cancer
|
|
JP7601635B2
(ja)
*
|
2017-06-25 |
2024-12-17 |
システィミューン， インク． |
抗ｐｄ－１抗体とその作製及び使用方法
|
|
AU2018292618A1
(en)
|
2017-06-27 |
2019-12-19 |
Novartis Ag |
Dosage regimens for anti-TIM-3 antibodies and uses thereof
|
|
EP3421494A1
(en)
|
2017-06-29 |
2019-01-02 |
Sanofi |
Use of isatuximab in combination with an anti-pd-1 antibody
|
|
MX2020000228A
(es)
|
2017-07-06 |
2020-08-10 |
Regeneron Pharma |
Proceso de cultivo celular para producir una glicoproteina.
|
|
SG11202000248UA
(en)
|
2017-07-14 |
2020-02-27 |
Innate Tumor Immunity Inc |
Nlrp3 modulators
|
|
KR20250025039A
(ko)
|
2017-07-20 |
2025-02-20 |
노파르티스 아게 |
항-lag-3 항체의 투여 요법 및 그의 용도
|
|
KR102880156B1
(ko)
*
|
2017-07-24 |
2025-11-05 |
리제너론 파마슈티칼스 인코포레이티드 |
항cd8 항체 및 이의 용도
|
|
TWI799432B
(zh)
|
2017-07-27 |
2023-04-21 |
美商再生元醫藥公司 |
抗ctla-4抗體及其用途
|
|
CN110997691B
(zh)
|
2017-07-28 |
2023-11-07 |
百时美施贵宝公司 |
作为抗癌剂的环二核苷酸
|
|
WO2019027847A1
(en)
*
|
2017-07-29 |
2019-02-07 |
University Of Southern California |
SYNTHETIC EXTRACELLULAR VESICLES FOR NEW THERAPIES
|
|
CA3071376A1
(en)
|
2017-08-03 |
2019-02-07 |
Amgen Inc. |
Interleukin-21 muteins and methods of treatment
|
|
US10947263B2
(en)
|
2017-08-31 |
2021-03-16 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
KR20250021628A
(ko)
|
2017-08-31 |
2025-02-13 |
브리스톨-마이어스 스큅 컴퍼니 |
항암제로서의 시클릭 디뉴클레오티드
|
|
EP3676279B1
(en)
|
2017-08-31 |
2021-12-01 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
JP2020532991A
(ja)
|
2017-09-07 |
2020-11-19 |
オーガスタ ユニバーシティ リサーチ インスティテュート，インコーポレーテッド |
プログラム細胞死タンパク質１に対する抗体
|
|
WO2019055579A1
(en)
|
2017-09-12 |
2019-03-21 |
Tolero Pharmaceuticals, Inc. |
TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR
|
|
RU2020113600A
(ru)
|
2017-09-20 |
2021-10-20 |
Ридженерон Фармасьютикалз, Инк. |
Способы иммунотерапии пациентов, опухоли которых характеризуются высокой нагрузкой пассажирскими генными мутациями
|
|
EP3691643A4
(en)
|
2017-09-29 |
2021-06-16 |
Bristol-Myers Squibb Company |
COMPOSITIONS AND METHODS OF TREATMENT OF CANCER
|
|
WO2019074887A1
(en)
|
2017-10-10 |
2019-04-18 |
Bristol-Myers Squibb Company |
CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS
|
|
JP2020536894A
(ja)
|
2017-10-15 |
2020-12-17 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
腫瘍処置法
|
|
JP7254821B2
(ja)
|
2017-10-16 |
2023-04-10 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗がん剤としての環状ジヌクレオチド
|
|
US20210040205A1
(en)
|
2017-10-25 |
2021-02-11 |
Novartis Ag |
Antibodies targeting cd32b and methods of use thereof
|
|
KR20200074993A
(ko)
*
|
2017-11-03 |
2020-06-25 |
노파르티스 아게 |
쇼그렌 증후군 치료에 사용하기 위한 항-cd40 항체
|
|
CN111315397A
(zh)
|
2017-11-06 |
2020-06-19 |
百时美施贵宝公司 |
治疗肿瘤的方法
|
|
AU2018359967A1
(en)
|
2017-11-06 |
2020-04-23 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
SG11202004167XA
(en)
*
|
2017-11-08 |
2020-06-29 |
Epiaxis Therapeutics Pty Ltd |
Immunogenic compositions and uses therefor
|
|
AU2018368731A1
(en)
|
2017-11-16 |
2020-05-14 |
Novartis Ag |
Combination therapies
|
|
WO2019099977A2
(en)
|
2017-11-20 |
2019-05-23 |
Ariagen, Inc. |
Indole compounds and their use
|
|
TW201925782A
(zh)
|
2017-11-30 |
2019-07-01 |
瑞士商諾華公司 |
靶向bcma之嵌合抗原受體及其用途
|
|
US10946068B2
(en)
|
2017-12-06 |
2021-03-16 |
Pandion Operations, Inc. |
IL-2 muteins and uses thereof
|
|
US10174091B1
(en)
|
2017-12-06 |
2019-01-08 |
Pandion Therapeutics, Inc. |
IL-2 muteins
|
|
CN109912577B
(zh)
*
|
2017-12-12 |
2021-10-22 |
深圳先进技术研究院 |
用于抑制eb病毒相关肿瘤的化合物及其制备方法和用途
|
|
EP3728314A1
(en)
|
2017-12-19 |
2020-10-28 |
Kymab Limited |
Bispecific antibody for icos and pd-l1
|
|
GB201721338D0
(en)
|
2017-12-19 |
2018-01-31 |
Kymab Ltd |
Anti-icos Antibodies
|
|
JP7321159B2
(ja)
|
2017-12-22 |
2023-08-04 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
薬剤生成物不純物を特性決定するためのシステム及び方法
|
|
TW201930591A
(zh)
|
2018-01-08 |
2019-08-01 |
瑞士商諾華公司 |
用於與嵌合抗原受體療法併用之免疫增強rna
|
|
AU2019207895A1
(en)
|
2018-01-12 |
2020-06-18 |
Amgen Inc. |
Anti-PD-1 antibodies and methods of treatment
|
|
WO2019143607A1
(en)
|
2018-01-16 |
2019-07-25 |
Bristol-Myers Squibb Company |
Methods of treating cancer with antibodies against tim3
|
|
MX2020007526A
(es)
|
2018-01-22 |
2020-09-09 |
Bristol Myers Squibb Co |
Composiciones y metodos para tratar el cancer.
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
EP3743061A1
(en)
|
2018-01-22 |
2020-12-02 |
Pascal Biosciences Inc. |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
|
BR112020013336A2
(pt)
|
2018-01-31 |
2020-12-01 |
Regeneron Pharmaceuticals, Inc. |
produto farmacêutico proteico, métodos para caracterizar as impurezas do produto farmacêutico proteico de alto peso molecular intermediário, para produção de um anticorpo, e para caracterizar as impurezas de fármaco com variação de carga, anticorpo, e, sistema para caracterizar impurezas de fármaco de alto peso molecular intermediário.
|
|
CA3090249A1
(en)
|
2018-01-31 |
2019-08-08 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
KR102171766B1
(ko)
*
|
2018-02-02 |
2020-10-29 |
주식회사 뉴라클제네틱스 |
Pd-l1 결합력이 증대된 pd-1 변이체
|
|
TWI786265B
(zh)
|
2018-02-02 |
2022-12-11 |
美商再生元醫藥公司 |
用於表徵蛋白質二聚合之系統及方法
|
|
WO2019153200A1
(zh)
|
2018-02-08 |
2019-08-15 |
北京韩美药品有限公司 |
抗pd-1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
|
WO2019160956A1
(en)
|
2018-02-13 |
2019-08-22 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
US10519187B2
(en)
|
2018-02-13 |
2019-12-31 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
GB201802573D0
(en)
*
|
2018-02-16 |
2018-04-04 |
Crescendo Biologics Ltd |
Therapeutic molecules that bind to LAG3
|
|
MX2020008988A
(es)
|
2018-02-28 |
2020-09-28 |
Regeneron Pharma |
Sistemas y metodos para la identificacion de contaminantes virales.
|
|
RU2756899C1
(ru)
|
2018-02-28 |
2021-10-06 |
ЭйПи БАЙОСАЙЕНСИЗ, ИНК. |
Бифункциональные белки, комбинирующие блокаду контрольной точки, для таргетной терапии
|
|
KR20200130362A
(ko)
|
2018-03-08 |
2020-11-18 |
브리스톨-마이어스 스큅 컴퍼니 |
항암제로서의 시클릭 디뉴클레오티드
|
|
US12259355B2
(en)
|
2018-03-19 |
2025-03-25 |
Regeneron Pharmaceuticals, Inc. |
Microchip capillary electrophoresis assays and reagents
|
|
DK3768709T3
(da)
|
2018-03-19 |
2024-01-29 |
Regeneron Pharma |
Mikrochip-kapillærelektroforese-assays og reagenser
|
|
US12253490B2
(en)
|
2018-03-19 |
2025-03-18 |
Regeneron Pharmaceuticals, Inc. |
Microchip capillary electrophoresis assays and reagents
|
|
CN119899267A
(zh)
*
|
2018-03-22 |
2025-04-29 |
赛因格先进生物技术弗朗哥塞尔瓦托有限责任公司 |
拮抗性pd-1、pd-l1和lag-3结合蛋白
|
|
AU2019237257A1
(en)
*
|
2018-03-23 |
2020-10-15 |
ISR Immune System Regulation Holding AB (publ) |
Combinations of macrolide compounds and immune checkpoint inhibitors
|
|
JP7351845B2
(ja)
|
2018-03-23 |
2023-09-27 |
ブリストル－マイヤーズ スクイブ カンパニー |
Ｍｉｃａおよび／またはｍｉｃｂに対する抗体ならびにそれらの使用
|
|
CN108546297B
(zh)
*
|
2018-03-29 |
2019-08-02 |
中国人民解放军军事科学院军事医学研究院 |
针对pd-1的单克隆抗体及其应用
|
|
KR20200139724A
(ko)
|
2018-03-30 |
2020-12-14 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
JP7680208B2
(ja)
|
2018-04-04 |
2025-05-20 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗ｃｄ２７抗体およびその使用
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
CN109336975B
(zh)
*
|
2018-04-18 |
2022-05-13 |
中国科学院微生物研究所 |
一种靶向pd-1的肿瘤抑制性抗体及其应用
|
|
WO2019209896A1
(en)
|
2018-04-25 |
2019-10-31 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
CN108840932B
(zh)
*
|
2018-04-28 |
2022-03-29 |
中国科学院微生物研究所 |
一种pd-1特异性抗体及其抗肿瘤应用
|
|
CN110404066B
(zh)
*
|
2018-04-28 |
2022-06-17 |
齐鲁制药有限公司 |
一种抗人pd-1的单克隆抗体制剂、联合用药物及其用途
|
|
WO2019211489A1
(en)
|
2018-05-04 |
2019-11-07 |
Merck Patent Gmbh |
COMBINED INHIBITION OF PD-1/PD-L1, TGFβ AND DNA-PK FOR THE TREATMENT OF CANCER
|
|
TW202016125A
(zh)
|
2018-05-10 |
2020-05-01 |
美商再生元醫藥公司 |
用於定量及調節蛋白質黏度之系統與方法
|
|
BR112020023195A2
(pt)
|
2018-05-14 |
2021-09-28 |
Immunocore Limited |
Polipeptídeos de ligação bifuncional, composição farmacêutica, ácido nucleico, vetor de expressão, célula hospedeira, método para preparar o polipeptídeo de ligação bifuncional, e método para tratar um distúrbio autoimune
|
|
US11136394B2
(en)
|
2018-05-17 |
2021-10-05 |
Nanjing Leads Biolabs Co., Ltd. |
Antibody binding PD-1 and use thereof
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Ｅｎｔｐｄ２抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
TW202017569A
(zh)
|
2018-05-31 |
2020-05-16 |
美商佩樂敦治療公司 |
用於抑制cd73之組合物及方法
|
|
TWI848951B
(zh)
|
2018-06-01 |
2024-07-21 |
瑞士商諾華公司 |
針對ｂｃｍａ之結合分子及其用途
|
|
CA3104467A1
(en)
|
2018-06-20 |
2019-12-26 |
Incyte Corporation |
Anti-pd-1 antibodies and uses thereof
|
|
US11548947B2
(en)
|
2018-06-21 |
2023-01-10 |
Regeneron Pharmaceuticals, Inc. |
Bispecific anti-PSMA X anti-CD28 antibodies and uses thereof
|
|
TWI890661B
(zh)
|
2018-06-21 |
2025-07-21 |
美商再生元醫藥公司 |
用雙特異性抗CD3xMUC16抗體及抗PD-1抗體治療癌症的方法
|
|
EP3810653A1
(en)
|
2018-06-23 |
2021-04-28 |
F. Hoffmann-La Roche AG |
Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor
|
|
US11795206B2
(en)
*
|
2018-06-24 |
2023-10-24 |
Yunbiao Lu |
Specific bifunctional BY-001 (active composition of homomultimer of chimeric protein pd-L1 / fc-gamma1) down regulates the activation of human immune cells and the use thereof
|
|
WO2020006516A1
(en)
|
2018-06-29 |
2020-01-02 |
Gensun Biopharma, Inc. |
Antitumor immune checkpoint regulator antagonists
|
|
US11535669B2
(en)
*
|
2018-07-09 |
2022-12-27 |
Precigen, Inc. |
Fusion constructs and methods of using thereof
|
|
CA3103385A1
(en)
|
2018-07-10 |
2020-01-16 |
Novartis Ag |
3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and their use in the treatment of ikaros family zinc finger 2 (ikzf2)-dependent diseases
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
MX2021000558A
(es)
|
2018-07-18 |
2021-04-13 |
Genentech Inc |
Metodos para tratar el cancer de pulmon con un antagonista de fijacion al eje pd-1, un antimetabolito y un agente de platino.
|
|
EP3823991A4
(en)
*
|
2018-07-19 |
2022-08-03 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
ANTI-PD-1 ANTIBODIES, DOSAGE FORMS AND USES THEREOF
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
WO2020021061A1
(en)
|
2018-07-26 |
2020-01-30 |
Pieris Pharmaceuticals Gmbh |
Humanized anti-pd-1 antibodies and uses thereof
|
|
KR20210040080A
(ko)
|
2018-07-26 |
2021-04-12 |
브리스톨-마이어스 스큅 컴퍼니 |
암의 치료를 위한 lag-3 조합 요법
|
|
JP7433291B2
(ja)
|
2018-08-16 |
2024-02-19 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
イミダゾ［４，５－ｃ］キノリン誘導体のＮＬＲＰ３モジュレーター
|
|
SG11202101486RA
(en)
|
2018-08-16 |
2021-03-30 |
Innate Tumor Immunity Inc |
Substitued 4-amino-1h-imidazo[4,5-c]quinoline compounds and improved methods for their preparation
|
|
EP3837014B1
(en)
|
2018-08-16 |
2022-10-19 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
TW202026423A
(zh)
|
2018-08-24 |
2020-07-16 |
法商賽諾菲公司 |
用於實體瘤癌症的治療性ｒｎａ
|
|
AU2019328632A1
(en)
|
2018-08-27 |
2021-03-25 |
Pieris Pharmaceuticals Gmbh |
Combination therapies comprising CD137/HER2 bispecific agents and PD-1 axis inhibitors and uses thereof
|
|
IL280880B2
(en)
|
2018-08-27 |
2025-04-01 |
Regeneron Pharma |
Using Raman Spectroscopy in Downstream Purification
|
|
BR112020026348A2
(pt)
|
2018-08-30 |
2021-03-30 |
Regeneron Pharmaceuticals, Inc. |
Método para avaliar a estequiometria e distribuição de tamanho de complexos de proteínas, para selecionar um medicamento de proteína principal e para caracterizar complexos de proteínas, e, composição farmacêutica
|
|
WO2020044252A1
(en)
|
2018-08-31 |
2020-03-05 |
Novartis Ag |
Dosage regimes for anti-m-csf antibodies and uses thereof
|
|
RS66543B1
(sr)
|
2018-08-31 |
2025-03-31 |
Regeneron Pharma |
Strategija doziranja koja ublažava sindrom oslobađanja citokina za cd3/cd20 bispecifična antitela
|
|
WO2020051099A1
(en)
|
2018-09-03 |
2020-03-12 |
Genentech, Inc. |
Carboxamide and sulfonamide derivatives useful as tead modulators
|
|
WO2020049534A1
(en)
|
2018-09-07 |
2020-03-12 |
Novartis Ag |
Sting agonist and combination therapy thereof for the treatment of cancer
|
|
KR20210072059A
(ko)
|
2018-10-09 |
2021-06-16 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하기 위한 항-MerTK 항체
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
JP2022504905A
(ja)
|
2018-10-16 |
2022-01-13 |
ノバルティス アーゲー |
標的化療法に対する応答を予測するためのバイオマーカーとしての単独の又は免疫マーカーと組み合わせた腫瘍突然変異負荷
|
|
PL3866850T3
(pl)
|
2018-10-19 |
2024-10-14 |
Bristol-Myers Squibb Company |
Terapia skojarzona czerniaka
|
|
KR20210081384A
(ko)
|
2018-10-23 |
2021-07-01 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
WO2020089811A1
(en)
|
2018-10-31 |
2020-05-07 |
Novartis Ag |
Dc-sign antibody drug conjugates
|
|
BR112021008582A8
(pt)
*
|
2018-11-05 |
2023-02-07 |
Merck Sharp & Dohme |
Regime de dosagem de anticorpo anti-tigit para tratamento de câncer
|
|
MX2021005594A
(es)
*
|
2018-11-13 |
2021-10-22 |
Compass Therapeutics Llc |
Constructos multiespecificos de union contra moleculas de puntos de control y usos de los mismos.
|
|
PT3880186T
(pt)
|
2018-11-14 |
2024-05-28 |
Regeneron Pharma |
Administração intralesional de inibidores de pd-1 para o tratamento do cancro de pele
|
|
TW202033555A
(zh)
|
2018-11-16 |
2020-09-16 |
美商必治妥美雅史谷比公司 |
抗nkg2a抗體及其用途
|
|
US20230054194A1
(en)
|
2018-11-19 |
2023-02-23 |
Ariagen, Inc. |
Methods of Treating Cancer
|
|
US20220016277A1
(en)
|
2018-11-20 |
2022-01-20 |
Cornell University |
Macrocyclic complexes of radionuclides and their use in radiotherapy of cancer
|
|
AU2019392090A1
(en)
|
2018-12-03 |
2021-06-17 |
Agensys, Inc. |
Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof
|
|
US11034710B2
(en)
|
2018-12-04 |
2021-06-15 |
Sumitomo Dainippon Pharma Oncology, Inc. |
CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
|
US20220099637A1
(en)
|
2018-12-04 |
2022-03-31 |
Bristol-Myers Squibb Company |
Methods of analysis using in-sample calibration curve by multiple isotopologue reaction monitoring
|
|
EP3666905A1
(en)
*
|
2018-12-11 |
2020-06-17 |
Sanofi |
E. coli positive for pks island as marker of positive response to anti-pd1 therapy in colorectal cancer
|
|
CN113195467A
(zh)
|
2018-12-11 |
2021-07-30 |
施万生物制药研发Ip有限责任公司 |
适用作alk5抑制剂的萘啶和喹啉衍生物
|
|
JP7637052B2
(ja)
|
2018-12-19 |
2025-02-27 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
二重特異性抗ｃｄ２８ｘ抗ｃｄ２２抗体及びその使用
|
|
US12304946B2
(en)
*
|
2018-12-19 |
2025-05-20 |
Humabs Biomed Sa |
Antibodies that neutralize hepatitis B virus and uses thereof
|
|
JP7588586B2
(ja)
|
2018-12-19 |
2024-11-22 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
二重特異性抗ｍｕｃ１６×抗ｃｄ２８抗体およびその使用
|
|
WO2020128972A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
KR20210126559A
(ko)
|
2018-12-20 |
2021-10-20 |
비르 바이오테크놀로지, 인코포레이티드 |
병용 hbv 요법
|
|
CN113166762B
(zh)
|
2018-12-21 |
2025-01-14 |
瓦莱里奥治疗公司 |
新的偶联核酸分子及其用途
|
|
EP3898674A1
(en)
|
2018-12-21 |
2021-10-27 |
Novartis AG |
Use of il-1beta binding antibodies
|
|
AU2019406840A1
(en)
|
2018-12-21 |
2021-06-03 |
Novartis Ag |
Use of IL-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome
|
|
EP3897613A1
(en)
|
2018-12-21 |
2021-10-27 |
Novartis AG |
Use of il-1beta binding antibodies
|
|
WO2020128637A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 binding antibodies in the treatment of a msi-h cancer
|
|
CN113228190B
(zh)
|
2018-12-23 |
2024-06-11 |
豪夫迈·罗氏有限公司 |
分类和/或鉴定癌症亚型的系统和方法
|
|
CA3124971A1
(en)
*
|
2018-12-27 |
2020-07-02 |
Gigagen, Inc. |
Anti-pd-1 binding proteins and methods of use thereof
|
|
CA3124837A1
(en)
|
2019-01-14 |
2020-07-23 |
Genentech, Inc. |
Methods of treating cancer with a pd-1 axis binding antagonist and an rna vaccine
|
|
WO2020150116A1
(en)
|
2019-01-14 |
2020-07-23 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
EP3911416B1
(en)
|
2019-01-14 |
2024-06-12 |
Innate Tumor Immunity, Inc. |
Substituted quinazolines as nlrp3 modulators, for use in the treatment of cancer
|
|
WO2020150114A1
(en)
|
2019-01-14 |
2020-07-23 |
Innate Tumor Immunity, Inc. |
Heterocyclic nlrp3 modulators, for use in the treatment of cancer
|
|
EP3911641A1
(en)
|
2019-01-14 |
2021-11-24 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
FI3857237T3
(fi)
|
2019-01-16 |
2023-05-03 |
Regeneron Pharma |
Disulfidisidosten luonnehtimismenetelmiä
|
|
JP2022518236A
(ja)
|
2019-01-21 |
2022-03-14 |
サノフイ |
進行期固形腫瘍がんに対する治療用ｒｎａおよび抗ｐｄ１抗体
|
|
CA3128064A1
(en)
|
2019-02-01 |
2020-08-06 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments for cancer comprising belantamab mafodotin and an anti ox40 antibody and uses and methods thereof
|
|
CA3127502A1
(en)
|
2019-02-12 |
2020-08-20 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
|
EP3923940B1
(en)
|
2019-02-12 |
2025-12-03 |
Novartis AG |
Pharmaceutical combination comprising tno155 and a pd-1 inhibitor
|
|
ES3032659T3
(en)
|
2019-02-15 |
2025-07-23 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
ES2982474T3
(es)
|
2019-02-15 |
2024-10-16 |
Novartis Ag |
Derivados de 3-(1-oxoisoindolin-2-il)piperidin-1,6-diona sustituidos y usos de estos
|
|
SG11202108089SA
(en)
*
|
2019-02-28 |
2021-08-30 |
Regeneron Pharma |
Administration of pd-1 inhibitors for treating skin cancer
|
|
CA3129963A1
(en)
*
|
2019-03-06 |
2020-09-10 |
Regeneron Pharmaceuticals, Inc. |
Il-4/il-13 pathway inhibitors for enhanced efficacy in treating cancer
|
|
AU2020234785A1
(en)
|
2019-03-13 |
2021-08-19 |
Merck Sharp & Dohme Llc |
Anti-cancer combination therapies comprising CTLA-4 and PD-1 blocking agents
|
|
US11793802B2
(en)
|
2019-03-20 |
2023-10-24 |
Sumitomo Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (AML) with venetoclax failure
|
|
WO2020198077A1
(en)
|
2019-03-22 |
2020-10-01 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Compositions comprising pkm2 modulators and methods of treatment using the same
|
|
EP3941941A1
(en)
|
2019-03-22 |
2022-01-26 |
Regeneron Pharmaceuticals, Inc. |
Egfr x cd28 multispecific antibodies
|
|
US20220041733A1
(en)
|
2019-03-28 |
2022-02-10 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
US20220195046A1
(en)
|
2019-03-28 |
2022-06-23 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
CA3134080A1
(en)
|
2019-04-12 |
2020-10-15 |
Vascular Biogenics Ltd. |
Methods of anti-tumor therapy
|
|
EP3956327A1
(en)
|
2019-04-15 |
2022-02-23 |
Ariagen, Inc. |
Chiral indole compounds and their use
|
|
EP3725370A1
(en)
|
2019-04-19 |
2020-10-21 |
ImmunoBrain Checkpoint, Inc. |
Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease
|
|
BR112021020867A2
(pt)
|
2019-04-19 |
2022-01-04 |
Genentech Inc |
Anticorpos, ácido nucleico, vetor, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, usos do anticorpo, método de tratamento de um indivíduo com câncer e método para reduzir a depuração
|
|
WO2020231766A1
(en)
|
2019-05-13 |
2020-11-19 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
|
PH12021552675A1
(en)
|
2019-05-13 |
2022-07-04 |
Regeneron Pharma |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating cancer
|
|
US20200363400A1
(en)
|
2019-05-13 |
2020-11-19 |
Regeneron Pharmaceuticals, Inc. |
Competitive Ligand Binding Assays
|
|
US12012374B2
(en)
|
2019-05-13 |
2024-06-18 |
Bristol-Myers Squibb Company |
Agonists of ROR GAMMAt
|
|
EP3972992A4
(en)
|
2019-05-20 |
2023-07-19 |
Pandion Operations, Inc. |
MADCAM TARGETED IMMUNOTLERANCE
|
|
CA3141531A1
(en)
|
2019-05-24 |
2020-12-03 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
|
US20220363760A1
(en)
|
2019-05-30 |
2022-11-17 |
Bristol-Myers Squibb Company |
Multi-tumor gene signature for suitability to immuno-oncology therapy
|
|
WO2020243570A1
(en)
|
2019-05-30 |
2020-12-03 |
Bristol-Myers Squibb Company |
Cell localization signature and combination therapy
|
|
JP2022534982A
(ja)
|
2019-05-30 |
2022-08-04 |
ブリストル－マイヤーズ スクイブ カンパニー |
細胞局在化シグネチャーおよびその使用
|
|
AU2020290971A1
(en)
*
|
2019-06-14 |
2021-12-23 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against PD-1 and methods of use thereof
|
|
WO2020255011A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 or anti-pd-l1 antibody
|
|
JP2022537324A
(ja)
|
2019-06-18 |
2022-08-25 |
ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー |
Ｂ型肝炎ウイルス（ｈｂｖ）ワクチンおよび抗ｐｄ－１抗体の組合せ
|
|
WO2020263312A1
(en)
|
2019-06-28 |
2020-12-30 |
Gensun Biopharma, Inc. |
ANTITUMOR ANTAGONIST CONSISTING OF A MUTATED TGFβ1 - RII EXTRACELLULAR DOMAIN AND AN IMMUNOGLOBULIN SCAFFOLD
|
|
US11529350B2
(en)
|
2019-07-03 |
2022-12-20 |
Sumitomo Pharma Oncology, Inc. |
Tyrosine kinase non-receptor 1 (TNK1) inhibitors and uses thereof
|
|
CA3145857A1
(en)
*
|
2019-07-03 |
2021-01-07 |
Regeneron Pharmaceuticals, Inc. |
Anti-new york esophageal squamous cell carcinoma 1 (ny-eso-1) antigen-binding proteins and methods of use thereof
|
|
TWI889320B
(zh)
|
2019-07-05 |
2025-07-01 |
日商小野藥品工業股份有限公司 |
以pd-1/cd3雙特異性蛋白質所進行之血液性癌症治療
|
|
WO2021005607A1
(en)
*
|
2019-07-09 |
2021-01-14 |
National Institute For Biotechnology In The Negev Ltd. |
Antibodies with reduced immunogenicity
|
|
US20210032322A1
(en)
*
|
2019-08-01 |
2021-02-04 |
Vaccinex, Inc. |
Combined inhibition of semaphorin-4d and tgf-beta and compositions therefor
|
|
WO2021026074A1
(en)
*
|
2019-08-02 |
2021-02-11 |
University Of Virginia Patent Foundation |
Bispecific antibody targeting of t regulatory cells for treatment of inflammatory conditions
|
|
WO2021026179A1
(en)
|
2019-08-06 |
2021-02-11 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
EP4011918A4
(en)
|
2019-08-08 |
2023-08-23 |
ONO Pharmaceutical Co., Ltd. |
DUAL SPECIFIC PROTEIN
|
|
US11629190B2
(en)
|
2019-08-15 |
2023-04-18 |
Oregon State University |
Canine antibody therapeutic for treating cancer
|
|
US20220348651A1
(en)
|
2019-09-18 |
2022-11-03 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與ｅｎｔｐｄ２抗體之組合療法
|
|
WO2021055994A1
(en)
|
2019-09-22 |
2021-03-25 |
Bristol-Myers Squibb Company |
Quantitative spatial profiling for lag-3 antagonist therapy
|
|
CN120334439A
(zh)
|
2019-09-24 |
2025-07-18 |
里珍纳龙药品有限公司 |
用于色谱介质的使用和再生的系统及方法
|
|
KR20220069964A
(ko)
|
2019-09-25 |
2022-05-27 |
씨젠 인크. |
조혈암의 치료를 위한 항-cd30 adc, 항-pd-1 및 화학치료제 조합
|
|
US20220339249A1
(en)
|
2019-09-25 |
2022-10-27 |
Bristol-Myers Squibb Company |
Composite biomarker for cancer therapy
|
|
CN114786680A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
Tim-3抑制剂及其用途
|
|
CN114786679A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
具有维奈托克和tim-3抑制剂的组合疗法
|
|
US12297451B1
(en)
|
2019-10-25 |
2025-05-13 |
Regeneron Pharmaceuticals, Inc. |
Cell culture medium
|
|
WO2021091964A1
(en)
|
2019-11-04 |
2021-05-14 |
Duke University |
Treatment for primary and metastatic cancer
|
|
CN114901677A
(zh)
*
|
2019-11-04 |
2022-08-12 |
艾诺奥医药品有限公司 |
治疗脑癌的联合疗法
|
|
KR20220092578A
(ko)
|
2019-11-05 |
2022-07-01 |
브리스톨-마이어스 스큅 컴퍼니 |
M-단백질 검정 및 이의 용도
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
IL291748A
(en)
|
2019-11-07 |
2022-06-01 |
Oncxerna Therapeutics Inc |
Classification of growth microenvironments
|
|
US20220411499A1
(en)
|
2019-11-08 |
2022-12-29 |
Bristol-Myers Squibb Company |
LAG-3 Antagonist Therapy for Melanoma
|
|
CN114728905B
(zh)
|
2019-11-13 |
2025-08-01 |
基因泰克公司 |
治疗性化合物及使用方法
|
|
EP4058465A1
(en)
|
2019-11-14 |
2022-09-21 |
Cohbar Inc. |
Cxcr4 antagonist peptides
|
|
JP2023502662A
(ja)
|
2019-11-22 |
2023-01-25 |
セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー |
Ａｌｋ５阻害剤としての置換１，５－ナフチリジンまたはキノリン
|
|
JP2023502264A
(ja)
|
2019-11-22 |
2023-01-23 |
スミトモ ファーマ オンコロジー， インコーポレイテッド |
固体用量医薬組成物
|
|
CN119318636A
(zh)
|
2019-11-25 |
2025-01-17 |
里珍纳龙药品有限公司 |
使用非水性乳液的持续释放调配物
|
|
BR112022011268A2
(pt)
|
2019-12-09 |
2022-09-06 |
Seagen Inc |
Terapia de combinação com antagonista de liv1-adc e pd1
|
|
BR112022009631A2
(pt)
|
2019-12-19 |
2022-08-09 |
Bristol Myers Squibb Co |
Combinações de inibidores de dgk e antagonistas do ponto de checagem
|
|
WO2021121373A1
(zh)
*
|
2019-12-20 |
2021-06-24 |
广东菲鹏制药股份有限公司 |
抗人程序死亡因子-1单克隆抗体
|
|
MX2022007759A
(es)
|
2019-12-20 |
2022-07-19 |
Novartis Ag |
Combinacion del anticuerpo anti tim-3 mbg453 y anticuerpo anti tgf-beta nis793, con o sin decitabina o el anticuerpo anti pd-1 spartalizumab, para el tratamiento de mielofibrosis y sindrome mielodisplasico.
|
|
KR20220127848A
(ko)
|
2020-01-10 |
2022-09-20 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
Nlrp3 조정제
|
|
EP4090335A1
(en)
|
2020-01-17 |
2022-11-23 |
Novartis AG |
Combination comprising a tim-3 inhibitor and a hypomethylating agent for use in treating myelodysplastic syndrome or chronic myelomonocytic leukemia
|
|
EP4354145B1
(en)
|
2020-01-21 |
2025-09-17 |
Regeneron Pharmaceuticals, Inc. |
Deglycosylation methods for electrophoresis of glycosylated proteins
|
|
KR20210095781A
(ko)
|
2020-01-24 |
2021-08-03 |
주식회사 에이프릴바이오 |
항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물
|
|
US20230086099A1
(en)
|
2020-01-30 |
2023-03-23 |
Ona Therapeutics, S.L. |
Combination therapy for treatment of cancer and cancer metastasis
|
|
EP4096708A1
(en)
|
2020-01-31 |
2022-12-07 |
Genentech, Inc. |
Methods of inducing neoepitope-specific t cells with a pd-1 axis binding antagonist and an rna vaccine
|
|
US20230087600A1
(en)
|
2020-02-06 |
2023-03-23 |
Bristol-Myers Squibb Company |
Il-10 and uses thereof
|
|
CN113244385A
(zh)
*
|
2020-02-07 |
2021-08-13 |
上海君实生物医药科技股份有限公司 |
抗pd-1抗体在治疗恶性肿瘤中的用途
|
|
WO2021168079A1
(en)
|
2020-02-21 |
2021-08-26 |
Pandion Operations, Inc. |
Tissue targeted immunotolerance with a cd39 effector
|
|
EP4110341A2
(en)
|
2020-02-28 |
2023-01-04 |
Novartis AG |
A triple pharmaceutical combination comprising dabrafenib, an erk inhibitor and a raf inhibitor
|
|
WO2021178814A1
(en)
|
2020-03-06 |
2021-09-10 |
Regeneron Pharmaceuticals, Inc. |
Anti-gitr antibodies and uses thereof
|
|
CA3170456A1
(en)
|
2020-03-06 |
2021-09-10 |
Ellen Filvaroff |
Combination of an lsd-1 inhibitor and nivolumab for use in treating sclc or sqnsclc
|
|
MX2022011050A
(es)
|
2020-03-06 |
2022-12-15 |
Ona Therapeutics S L |
Anticuerpos anti-cd36 y su uso para tratar cancer.
|
|
CA3172697A1
(en)
|
2020-03-23 |
2021-09-30 |
Ruth Yin-Zong LAN |
Anti-ccr8 antibodies for treating cancer
|
|
US20230107609A1
(en)
*
|
2020-03-26 |
2023-04-06 |
Cureimmune Therapeutics Inc. |
Anti-pd-1 antibodies and methods of use
|
|
WO2021191870A1
(en)
|
2020-03-27 |
2021-09-30 |
Dcprime B.V. |
Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
|
|
JP2023519673A
(ja)
|
2020-03-31 |
2023-05-12 |
セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー |
置換ピリミジンおよび使用方法
|
|
US20230287081A1
(en)
*
|
2020-04-16 |
2023-09-14 |
Nantong Yichen Biopharma. Co. Ltd. |
PD-1 mutant polypeptide and preparation and application thereof
|
|
IL296226A
(en)
|
2020-04-21 |
2022-11-01 |
Novartis Ag |
Dosing regimen for treating a disease modulated by csf-1r
|
|
KR20230004682A
(ko)
|
2020-04-22 |
2023-01-06 |
머크 샤프 앤드 돔 엘엘씨 |
인터류킨-2 수용체 베타 감마c 이량체에 대해 편향되고 비펩티드성 수용성 중합체에 접합된 인간 인터류킨-2 접합체
|
|
CN115666724A
(zh)
*
|
2020-05-26 |
2023-01-31 |
瑞泽恩制药公司 |
通过施用pd-1抑制剂抗体西米普利单抗来治疗宫颈癌的方法
|
|
LT4157876T
(lt)
|
2020-05-26 |
2024-10-25 |
Boehringer Ingelheim International Gmbh |
Anti-pd-1 antikūnai
|
|
US20230203157A1
(en)
*
|
2020-05-27 |
2023-06-29 |
Dana-Farber Cancer Institute, Inc. |
Bispecific molecules for selectively modulating t cells
|
|
CR20220611A
(es)
|
2020-06-02 |
2023-06-07 |
Arcus Biosciences Inc |
Anticuerpos anti-tigit
|
|
EP4165041A1
(en)
|
2020-06-10 |
2023-04-19 |
Theravance Biopharma R&D IP, LLC |
Naphthyridine derivatives useful as alk5 inhibitors
|
|
AR122644A1
(es)
|
2020-06-19 |
2022-09-28 |
Onxeo |
Nuevas moléculas de ácido nucleico conjugado y sus usos
|
|
MX2022015852A
(es)
|
2020-06-23 |
2023-01-24 |
Novartis Ag |
Regimen de dosificacion que comprende derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona.
|
|
EP4171617A1
(en)
|
2020-06-30 |
2023-05-03 |
Mendus B.V. |
Use of leukemia-derived cells in ovarian cancer vaccines
|
|
MX2023000197A
(es)
|
2020-07-07 |
2023-02-22 |
BioNTech SE |
Arn terapeutico para el cancer positivo para vph.
|
|
WO2022009157A1
(en)
|
2020-07-10 |
2022-01-13 |
Novartis Ag |
Lhc165 and spartalizumab combinations for treating solid tumors
|
|
WO2022011256A1
(en)
|
2020-07-10 |
2022-01-13 |
Precigen, Inc. |
Fusion constructs and methods of using thereof
|
|
US11787775B2
(en)
|
2020-07-24 |
2023-10-17 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
EP4188549A1
(en)
|
2020-08-03 |
2023-06-07 |
Novartis AG |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
JP2023540217A
(ja)
|
2020-08-26 |
2023-09-22 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
Ｐｄ－１阻害剤を投与することによりがんを処置する方法
|
|
CA3193421A1
(en)
|
2020-08-28 |
2022-03-03 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hepatocellular carcinoma
|
|
US20230321285A1
(en)
|
2020-08-31 |
2023-10-12 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
CN116348599A
(zh)
*
|
2020-08-31 |
2023-06-27 |
博奥信生物技术（南京）有限公司 |
Pd-1结合抗体及其用途
|
|
EP4204453A1
(en)
|
2020-08-31 |
2023-07-05 |
Bristol-Myers Squibb Company |
Cell localization signature and immunotherapy
|
|
EP4204020A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
BR112023003273A2
(pt)
|
2020-08-31 |
2023-05-02 |
Regeneron Pharma |
Estratégias de alimentação de asparagina para melhorar desempenho da cultura celular e mitigar variantes da sequência de asparagina
|
|
WO2022049526A1
(en)
|
2020-09-02 |
2022-03-10 |
Pharmabcine Inc. |
Combination therapy of a pd-1 antagonist and an antagonist for vegfr-2 for treating patients with cancer
|
|
CA3170207A1
(en)
|
2020-09-03 |
2022-03-10 |
Chieh-I CHEN |
Methods of treating cancer pain by administering a pd-1 inhibitor
|
|
MX2023002884A
(es)
|
2020-09-14 |
2023-03-31 |
Boehringer Ingelheim Int |
Vacuna heterologa de estimulo primario.
|
|
WO2022061098A1
(en)
|
2020-09-18 |
2022-03-24 |
Regeneron Pharmaceuticals, Inc. |
Antigen-binding molecules that bind cd38 and/or cd28, and uses thereof
|
|
EP4217394A1
(en)
|
2020-09-24 |
2023-08-02 |
Merck Sharp & Dohme LLC |
Stable formulations of programmed death receptor 1 (pd-1) antibodies and hyaluronidase variants and fragments thereof and methods of use thereof
|
|
US20230374160A1
(en)
|
2020-10-02 |
2023-11-23 |
Regeneron Pharmaceuticals, Inc. |
Combination of antibodies for treating cancer with reduced cytokine release syndrome
|
|
CN116406369A
(zh)
|
2020-10-05 |
2023-07-07 |
百时美施贵宝公司 |
用于浓缩蛋白质的方法
|
|
US20230364127A1
(en)
|
2020-10-06 |
2023-11-16 |
Codiak Biosciences, Inc. |
Extracellular vesicle-aso constructs targeting stat6
|
|
AR123855A1
(es)
|
2020-10-20 |
2023-01-18 |
Genentech Inc |
Anticuerpos anti-mertk conjugados con peg y métodos de uso
|
|
EP4232019A1
(en)
|
2020-10-23 |
2023-08-30 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for lung cancer
|
|
WO2022093981A1
(en)
|
2020-10-28 |
2022-05-05 |
Genentech, Inc. |
Combination therapy comprising ptpn22 inhibitors and pd-l1 binding antagonists
|
|
WO2022094567A1
(en)
|
2020-10-28 |
2022-05-05 |
Ikena Oncology, Inc. |
Combination of an ahr inhibitor with a pdx inhibitor or doxorubicine
|
|
TWI888665B
(zh)
|
2020-11-04 |
2025-07-01 |
美商建南德克公司 |
抗cd20/抗cd3雙特異性抗體之皮下給藥
|
|
CA3196191A1
(en)
|
2020-11-04 |
2022-05-12 |
Chi-Chung Li |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies and anti-cd79b antibody drug conjugates
|
|
US12351643B2
(en)
|
2020-11-04 |
2025-07-08 |
Genentech, Inc. |
Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
|
|
AU2021373366A1
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
EP4243852A4
(en)
*
|
2020-11-13 |
2024-12-11 |
Ludwig Institute for Cancer Research Ltd |
PD-1 DECOY VARIANTS FOR IMMUNOTHERAPY
|
|
CA3191141A1
(en)
|
2020-11-25 |
2022-06-02 |
Hunter Chen |
Sustained release formulations using non-aqueous membrane emulsification
|
|
WO2022118197A1
(en)
|
2020-12-02 |
2022-06-09 |
Pfizer Inc. |
Time to resolution of axitinib-related adverse events
|
|
WO2022119830A1
(en)
|
2020-12-02 |
2022-06-09 |
Genentech, Inc. |
Methods and compositions for neoadjuvant and adjuvant urothelial carcinoma therapy
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Ａｌｋ﹘５抑制劑和彼之用途
|
|
US20240082394A1
(en)
*
|
2020-12-15 |
2024-03-14 |
Bicara Therapeutics Inc. |
Combination therapy for the treatment of cancer
|
|
WO2022133135A1
(en)
|
2020-12-17 |
2022-06-23 |
Regeneron Pharmaceuticals, Inc. |
Fabrication of protein-encapsulating microgels
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性ｒｎａ
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
US20220233689A1
(en)
|
2020-12-28 |
2022-07-28 |
Bristol-Myers Squibb Company |
Methods of treating tumors
|
|
RS66849B1
(sr)
|
2020-12-28 |
2025-06-30 |
Bristol Myers Squibb Co |
Kompozicije antitela i postupci njihove upotrebe
|
|
TW202233827A
(zh)
|
2021-01-20 |
2022-09-01 |
美商再生元醫藥公司 |
改良細胞培養中蛋白質效價的方法
|
|
CA3203705A1
(en)
|
2021-01-22 |
2022-07-28 |
Erik Hans MANTING |
Methods of tumor vaccination
|
|
JP2024505049A
(ja)
|
2021-01-29 |
2024-02-02 |
ノバルティス アーゲー |
抗ｃｄ７３及び抗ｅｎｔｐｄ２抗体のための投与方式並びにその使用
|
|
US20240109899A1
(en)
|
2021-02-04 |
2024-04-04 |
Bristol-Myers Squibb Company |
Benzofuran compounds as sting agonists
|
|
JP2024507144A
(ja)
|
2021-02-11 |
2024-02-16 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ネオアジュバントｐｄ－１阻害剤を投与することによってがんを処置する方法
|
|
AR125585A1
(es)
|
2021-03-03 |
2023-08-02 |
Regeneron Pharma |
Sistemas y métodos para cuantificar y modificar la viscosidad de proteínas
|
|
US20220305100A1
(en)
|
2021-03-12 |
2022-09-29 |
Dcprime B.V. |
Methods of vaccination and use of cd47 blockade
|
|
WO2022195551A1
(en)
|
2021-03-18 |
2022-09-22 |
Novartis Ag |
Biomarkers for cancer and methods of use thereof
|
|
WO2022204672A1
(en)
|
2021-03-23 |
2022-09-29 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer in immunosuppressed or immunocompromised patients by administering a pd-1 inhibitor
|
|
IL306090A
(en)
|
2021-03-25 |
2023-11-01 |
Oncxerna Therapeutics Inc |
Targeted cancer treatments
|
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
|
IL305731A
(en)
|
2021-03-26 |
2023-11-01 |
Regeneron Pharma |
Methods and systems for developing mixing protocols
|
|
KR20240005700A
(ko)
|
2021-03-29 |
2024-01-12 |
주노 쎄러퓨티크스 인코퍼레이티드 |
체크포인트 억제제 요법 및 car t 세포 요법의 조합을 사용한 투여 및 치료 방법
|
|
US20240376224A1
(en)
|
2021-04-02 |
2024-11-14 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
EP4323356A1
(en)
|
2021-04-13 |
2024-02-21 |
Nuvalent, Inc. |
Amino-substituted heterocycles for treating cancers with egfr mutations
|
|
WO2022232503A1
(en)
|
2021-04-30 |
2022-11-03 |
Genentech, Inc. |
Therapeutic and diagnostic methods and compositions for cancer
|
|
MX2023012408A
(es)
|
2021-04-30 |
2023-10-31 |
Hoffmann La Roche |
Dosis para tratamiento conjunto con anticuerpo biespecifico anti-cd20/anti-cd3 y conjugado anticuerpo farmaco anti-cd79b.
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
CA3218786A1
(en)
|
2021-05-25 |
2022-12-01 |
Lifei HOU |
C-x-c motif chemokine receptor 6 (cxcr6) binding molecules, and methods of using the same
|
|
WO2022251359A1
(en)
|
2021-05-26 |
2022-12-01 |
Theravance Biopharma R&D Ip, Llc |
Bicyclic inhibitors of alk5 and methods of use
|
|
BR112023024984A2
(pt)
|
2021-06-01 |
2024-02-20 |
Regeneron Pharma |
Tampão de amostra de eletroforese aquosa, método para identificar contaminantes ou impurezas em uma amostra de droga proteica, e, kit
|
|
WO2022256534A1
(en)
|
2021-06-03 |
2022-12-08 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and pembrolizumab
|
|
GB202107994D0
(en)
|
2021-06-04 |
2021-07-21 |
Kymab Ltd |
Treatment of cancer
|
|
TW202317623A
(zh)
*
|
2021-06-14 |
2023-05-01 |
美商再生元醫藥公司 |
基於il2之治療劑及其使用方法
|
|
WO2022266510A1
(en)
|
2021-06-18 |
2022-12-22 |
Genzyme Corporation |
Anti-tgf-beta antibody formulations and their use
|
|
KR20240028452A
(ko)
|
2021-07-02 |
2024-03-05 |
제넨테크, 인크. |
암을 치료하기 위한 방법 및 조성물
|
|
CA3225254A1
(en)
|
2021-07-13 |
2023-01-19 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
|
AU2022314735A1
(en)
|
2021-07-19 |
2024-02-22 |
Regeneron Pharmaceuticals, Inc. |
Combination of checkpoint inhibitors and an oncolytic virus for treating cancer
|
|
US20250066441A1
(en)
|
2021-07-19 |
2025-02-27 |
Regeneron Pharmaceuticals, Inc. |
Il12 receptor agonists and methods of use thereof
|
|
MX2024001214A
(es)
|
2021-07-28 |
2024-02-12 |
Hoffmann La Roche |
Metodos y composiciones para tratar cancer.
|
|
JP2024527049A
(ja)
|
2021-07-28 |
2024-07-19 |
ジェネンテック， インコーポレイテッド |
がんを治療するための方法及び組成物
|
|
IL309934A
(en)
|
2021-07-30 |
2024-03-01 |
Ona Therapeutics S L |
Anti-cd36 antibodies and their use to treat cancer
|
|
JP2024531192A
(ja)
|
2021-08-13 |
2024-08-29 |
イノビオ ファーマシューティカルズ，インコーポレイティド |
脳がんを治療するための併用療法
|
|
WO2023022965A2
(en)
|
2021-08-16 |
2023-02-23 |
Regeneron Pharmaceuticals, Inc. |
Novel il27 receptor agonists and methods of use thereof
|
|
TW202326138A
(zh)
|
2021-09-08 |
2023-07-01 |
美商再生元醫藥公司 |
用於定量抗體及其他含Ｆｃ蛋白之高通量及基於質譜之方法
|
|
CN118139881A
(zh)
*
|
2021-09-20 |
2024-06-04 |
瑞泽恩制药公司 |
控制抗体异质性的方法
|
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
BioNTech SE |
Treatment involving non-immunogenic rna for antigen vaccination and pd-1 axis binding antagonists
|
|
TW202321308A
(zh)
|
2021-09-30 |
2023-06-01 |
美商建南德克公司 |
使用抗ｔｉｇｉｔ抗體、抗ｃｄ３８抗體及ｐｄ—１軸結合拮抗劑治療血液癌症的方法
|
|
WO2023057882A1
(en)
|
2021-10-05 |
2023-04-13 |
Pfizer Inc. |
Combinations of azalactam compounds with a pd-1 axis binding antagonist for the treatment of cancer
|
|
WO2023057534A1
(en)
|
2021-10-06 |
2023-04-13 |
Genmab A/S |
Multispecific binding agents against pd-l1 and cd137 in combination
|
|
JP2024540835A
(ja)
|
2021-10-07 |
2024-11-06 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ｐＨメーター較正及び補正
|
|
IL311245A
(en)
|
2021-10-07 |
2024-05-01 |
Regeneron Pharma |
Systems and methods for pH modeling and control
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
CN118176167A
(zh)
|
2021-10-26 |
2024-06-11 |
瑞泽恩制药公司 |
用于产生实验室用水和分配处于不同温度的实验室用水的系统和方法
|
|
WO2023077090A1
(en)
|
2021-10-29 |
2023-05-04 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hematological cancer
|
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
|
WO2023080900A1
(en)
|
2021-11-05 |
2023-05-11 |
Genentech, Inc. |
Methods and compositions for classifying and treating kidney cancer
|
|
WO2023083439A1
(en)
|
2021-11-09 |
2023-05-19 |
BioNTech SE |
Tlr7 agonist and combinations for cancer treatment
|
|
MX2024005722A
(es)
|
2021-11-12 |
2024-05-28 |
Novartis Ag |
Terapia de combinacion para el tratamiento del cancer de pulmon.
|
|
US12110276B2
(en)
|
2021-11-24 |
2024-10-08 |
Genentech, Inc. |
Pyrazolo compounds and methods of use thereof
|
|
US12275745B2
(en)
|
2021-11-24 |
2025-04-15 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
CN116333118B
(zh)
*
|
2021-12-16 |
2024-04-19 |
徕特康(苏州)生物制药有限公司 |
抗表皮生长因子受体抗体及其制备方法和用途
|
|
EP4452327A1
(en)
|
2021-12-20 |
2024-10-30 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and pembrolizumab
|
|
EP4460520A1
(en)
|
2022-01-07 |
2024-11-13 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating recurrent ovarian cancer with bispecific anti-muc16 x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
|
|
JP2025503962A
(ja)
|
2022-01-26 |
2025-02-06 |
ブリストル－マイヤーズ スクイブ カンパニー |
肝細胞がんのための併用療法
|
|
WO2023147470A2
(en)
|
2022-01-28 |
2023-08-03 |
Georgiamune Inc. |
Antibodies to programmed cell death protein 1 that are pd-1 agonists
|
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|
|
US20250152643A1
(en)
|
2022-02-17 |
2025-05-15 |
Regeneron Pharmaceuticals, Inc. |
Combinations of checkpoint inhibitors and oncolytic virus for treating cancer
|
|
JP2025507694A
(ja)
|
2022-02-25 |
2025-03-21 |
ブリストル－マイヤーズ スクイブ カンパニー |
結腸直腸癌に対する組み合わせ療法
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
AU2023230110A1
(en)
|
2022-03-08 |
2024-10-24 |
Alentis Therapeutics Ag |
Use of anti-claudin-1 antibodies to increase t cell availability
|
|
IL315405A
(en)
|
2022-03-17 |
2024-11-01 |
Regeneron Pharma |
Methods for treating recurrent epithelioid sarcoma using bispecific anti-MUC16 and anti-CD3 antibodies alone or in combination with anti-PD-1 antibodies
|
|
KR20240159621A
(ko)
|
2022-03-18 |
2024-11-05 |
브리스톨-마이어스 스큅 컴퍼니 |
폴리펩티드를 단리하는 방법
|
|
CN119137473A
(zh)
|
2022-03-18 |
2024-12-13 |
里珍纳龙药品有限公司 |
分析多肽变体的方法及系统
|
|
CN119487067A
(zh)
|
2022-04-01 |
2025-02-18 |
基因泰克公司 |
用抗fcrh5/抗cd3双特异性抗体进行治疗的给药
|
|
CN116925223A
(zh)
*
|
2022-04-02 |
2023-10-24 |
普米斯生物技术(珠海)有限公司 |
抗pd-1单克隆抗体及其衍生物和用途
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
IL315992A
(en)
|
2022-04-08 |
2024-11-01 |
Bristol Myers Squibb Co |
Identification, classification and quantification of tertiary lymphoid structures using machine learning
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
IL316738A
(en)
|
2022-05-11 |
2024-12-01 |
Genentech Inc |
Dosage for treatment with anti-FCRH5/anti-CD3 bispecific antibodies
|
|
CN119546628A
(zh)
|
2022-05-11 |
2025-02-28 |
再生元制药公司 |
多特异性结合分子前蛋白及其用途
|
|
IL316628A
(en)
|
2022-05-12 |
2024-12-01 |
Genmab As |
Binding agents capable of binding to CD27 in combination therapy
|
|
WO2023224912A1
(en)
|
2022-05-16 |
2023-11-23 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating metastatic castration-resistant prostate cancer with bispecific anti-psma x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
|
|
IL316767A
(en)
|
2022-05-18 |
2025-01-01 |
Regeneron Pharma |
Multispecific antigen binding molecules that bind CD38 and 4-1BB and uses thereof
|
|
WO2023230554A1
(en)
|
2022-05-25 |
2023-11-30 |
Pfizer Inc. |
Combination of a braf inhibitor, an egfr inhibitor, and a pd-1 antagonist for the treatment of braf v600e-mutant, msi-h/dmmr colorectal cancer
|
|
WO2023230594A1
(en)
|
2022-05-27 |
2023-11-30 |
Regeneron Pharmaceuticals, Inc. |
Interleukin-2 proproteins and uses thereof
|
|
AU2023281061A1
(en)
|
2022-06-02 |
2024-12-05 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
WO2023235848A1
(en)
|
2022-06-04 |
2023-12-07 |
Regeneron Pharmaceuticals, Inc. |
Interleukin-2 proproteins and uses thereof
|
|
JP2025523387A
(ja)
|
2022-06-07 |
2025-07-23 |
ジェネンテック， インコーポレイテッド |
抗ｐｄ－ｌ１アンタゴニストおよび抗ｔｉｇｉｔアンタゴニスト抗体を含む、肺がん治療の有効性を判定するための方法
|
|
EP4554978A1
(en)
|
2022-07-13 |
2025-05-21 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
TW202413433A
(zh)
|
2022-07-19 |
2024-04-01 |
美商建南德克公司 |
用抗ｆｃｒｈ５／抗ｃｄ３雙特異性抗體進行治療之給藥
|
|
EP4310197A1
(en)
|
2022-07-21 |
2024-01-24 |
Fundación para la Investigación Biomédica del Hospital Universitario Puerta de Hierro Majadahonda |
Method for identifying lung cancer patients for a combination treatment of immuno- and chemotherapy
|
|
US20250368738A1
(en)
|
2022-07-22 |
2025-12-04 |
Philogen S.P.A |
Anti-cd28 antibodies
|
|
AU2023313118A1
(en)
|
2022-07-27 |
2025-03-06 |
Astrazeneca Ab |
Combinations of recombinant virus expressing interleukin-12 with pd-1/pd-l1 inhibitors
|
|
JP2025530983A
(ja)
|
2022-08-02 |
2025-09-19 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
二重特異性抗ｐｓｍａ×抗ｃｄ２８抗体を抗ｐｄ－１抗体と組み合わせて、転移性去勢抵抗性前立腺癌を治療する方法
|
|
EP4573110A1
(en)
|
2022-08-18 |
2025-06-25 |
Regeneron Pharmaceuticals, Inc. |
Interferon proproteins and uses thereof
|
|
US20240067691A1
(en)
|
2022-08-18 |
2024-02-29 |
Regeneron Pharmaceuticals, Inc. |
Interferon receptor agonists and uses thereof
|
|
WO2024040229A2
(en)
*
|
2022-08-19 |
2024-02-22 |
Flagship Pioneering Innovations V, Inc. |
Combination therapies comprising myc modulators and checkpoint inhibitors
|
|
EP4581366A1
(en)
|
2022-09-01 |
2025-07-09 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
|
WO2024069009A1
(en)
|
2022-09-30 |
2024-04-04 |
Alentis Therapeutics Ag |
Treatment of drug-resistant hepatocellular carcinoma
|
|
AU2023356866A1
(en)
|
2022-10-03 |
2025-04-17 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer with bispecific egfr x cd28 antibodies alone or in combination with anti-pd-1 antibodies
|
|
EP4599089A1
(en)
|
2022-10-05 |
2025-08-13 |
Genentech, Inc. |
Methods and compositions for classifying and treating bladder cancer
|
|
EP4599088A1
(en)
|
2022-10-05 |
2025-08-13 |
Genentech, Inc. |
Methods and compositions for classifying and treating lung cancer
|
|
EP4609201A1
(en)
|
2022-10-25 |
2025-09-03 |
Genentech, Inc. |
Therapeutic and diagnostic methods for multiple myeloma
|
|
CN120187759A
(zh)
|
2022-11-01 |
2025-06-20 |
海德堡医药研究有限责任公司 |
抗gucy2c抗体及其用途
|
|
CN120390652A
(zh)
|
2022-12-01 |
2025-07-29 |
免疫医疗有限公司 |
用于治疗癌症的包含抗pd-l1抗体和抗cd73抗体的组合疗法
|
|
WO2024115725A1
(en)
|
2022-12-01 |
2024-06-06 |
BioNTech SE |
Multispecific antibody against cd40 and cd137 in combination therapy with anti-pd1 ab and chemotherapy
|
|
AU2023393653A1
(en)
|
2022-12-14 |
2025-05-22 |
Astellas Pharma Europe Bv |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and immune checkpoint inhibitors
|
|
EP4634659A1
(en)
|
2022-12-16 |
2025-10-22 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for assessing chromatographic column integrity
|
|
TW202440154A
(zh)
|
2022-12-20 |
2024-10-16 |
美商建南德克公司 |
用ｐｄ－１軸結合拮抗劑及ｒｎａ疫苗治療胰臟癌之方法
|
|
AU2023409221A1
(en)
|
2022-12-21 |
2025-06-12 |
Bristol-Myers Squibb Company |
Combination therapy for lung cancer
|
|
TW202430560A
(zh)
|
2023-01-06 |
2024-08-01 |
美商拉森醫療公司 |
抗ｉｌ－１８ｂｐ抗體
|
|
CN120530131A
(zh)
|
2023-01-06 |
2025-08-22 |
拉森医疗公司 |
抗il-18bp抗体
|
|
WO2024150177A1
(en)
|
2023-01-11 |
2024-07-18 |
Advesya |
Treatment methods for solid tumors
|
|
WO2024151978A1
(en)
|
2023-01-13 |
2024-07-18 |
Regeneron Pharmaceuticals, Inc. |
Il12 receptor agonists and methods of use thereof
|
|
WO2024158880A1
(en)
|
2023-01-25 |
2024-08-02 |
Regeneron Pharmaceuticals, Inc. |
Methods of modeling liquid protein composition stability
|
|
EP4655595A1
(en)
|
2023-01-25 |
2025-12-03 |
Regeneron Pharmaceuticals, Inc. |
Mass spectrometry-based characterization of antibodies co-expressed in vivo
|
|
EP4658310A1
(en)
|
2023-01-30 |
2025-12-10 |
Kymab Limited |
Antibodies
|
|
TW202445138A
(zh)
|
2023-02-01 |
2024-11-16 |
美商再生元醫藥公司 |
用於生物巨分子分析之具質譜法的不對稱流場流分離
|
|
WO2024165403A1
(en)
|
2023-02-06 |
2024-08-15 |
Philogen S.P.A. |
Anti-cea antibodies
|
|
WO2024178213A2
(en)
|
2023-02-22 |
2024-08-29 |
Regeneron Pharmaceuticals, Inc. |
System suitability parameters and column aging
|
|
AU2024225483A1
(en)
|
2023-02-23 |
2025-08-28 |
Imcheck Therapeutics |
Combination of btn3a activating antibody and immune checkpoint inhibitors
|
|
IL322890A
(en)
|
2023-02-28 |
2025-10-01 |
Regeneron Pharma |
Multispecific molecules containing an MHC-peptide complex containing an MHC domain and an antigenic peptide and a partially targeted immune cell antigen
|
|
KR20250155054A
(ko)
|
2023-03-13 |
2025-10-29 |
리제너론 파마슈티칼스 인코포레이티드 |
흑색종 치료에서의 효능 강화를 위한 pd-1 억제제와 lag-3 억제제의 병용
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024209072A1
(en)
|
2023-04-06 |
2024-10-10 |
Genmab A/S |
Multispecific binding agents against pd-l1 and cd137 for treating cancer
|
|
WO2024223299A2
(en)
|
2023-04-26 |
2024-10-31 |
Isa Pharmaceuticals B.V. |
Methods of treating cancer by administering immunogenic compositions and a pd-1 inhibitor
|
|
WO2024229136A1
(en)
|
2023-05-01 |
2024-11-07 |
Regeneron Pharmaceuticals, Inc. |
Multidose antibody drug products using phenol or benzyl alcohol
|
|
WO2024233341A1
(en)
|
2023-05-05 |
2024-11-14 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2024233646A1
(en)
|
2023-05-10 |
2024-11-14 |
Genentech, Inc. |
Methods and compositions for treating cancer
|
|
AR132668A1
(es)
|
2023-05-12 |
2025-07-16 |
Genmab As |
Anticuerpos capaces de unirse a ox40, variantes de los mismos y usos de los mismos
|
|
WO2024236048A1
(en)
|
2023-05-16 |
2024-11-21 |
Nh Theraguix |
Combination therapy for treating tumors with radiotherapy
|
|
WO2024263195A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024263904A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024261239A1
(en)
|
2023-06-23 |
2024-12-26 |
Imcheck Therapeutics |
Bispecific antibodies targeting btn3a and the pd-1/pd-l1 inhibitory axis
|
|
WO2025024257A1
(en)
|
2023-07-21 |
2025-01-30 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
WO2025030041A1
(en)
|
2023-08-02 |
2025-02-06 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating metastatic castration-resistant prostate cancer with bispecific anti-psma x anti-cd28 antibodies
|
|
WO2025030044A1
(en)
|
2023-08-02 |
2025-02-06 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating clear cell renal cell carcinoma with bispecific anti-psma x anti-cd28 antibodies
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
WO2025049277A1
(en)
|
2023-08-25 |
2025-03-06 |
Genentech, Inc. |
Methods and compositions for treating non-small cell lung cancer comprising an anti-tigit antagonist antibody and a pd-1 axis binding antagonist
|
|
TW202528736A
(zh)
|
2023-09-08 |
2025-07-16 |
美商再生元醫藥公司 |
用於評估層析管柱完整性的方法及系統
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
US20250095773A1
(en)
|
2023-09-18 |
2025-03-20 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for developing chromatography protocols
|
|
US20250109905A1
(en)
|
2023-09-29 |
2025-04-03 |
Regeneron Pharmaceuticals, Inc. |
Lyophilization using controlled nucleation
|
|
AR134008A1
(es)
|
2023-10-02 |
2025-11-26 |
Regeneron Pharma |
Sistema de seguridad de dispositivo de administración de fármaco
|
|
WO2025080538A1
(en)
|
2023-10-09 |
2025-04-17 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer with a combination of a pd1 inhibitor and a targeted immunocytokine
|
|
WO2025085404A1
(en)
|
2023-10-16 |
2025-04-24 |
Genentech, Inc. |
Diagnostic and therapeutic methods for treating lung cancer
|
|
WO2025085594A1
(en)
|
2023-10-18 |
2025-04-24 |
Regeneron Pharmaceuticals, Inc. |
Rapid purification of monoclonal antibody from in-process upstream cell culture material
|
|
WO2025096932A1
(en)
|
2023-11-02 |
2025-05-08 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing lipase activity using stress
|
|
WO2025106469A1
(en)
|
2023-11-14 |
2025-05-22 |
Regeneron Pharmaceuticals, Inc. |
Engineered heavy chain variable domains and uses thereof
|
|
WO2025106736A2
(en)
|
2023-11-15 |
2025-05-22 |
Regeneron Pharmaceuticals, Inc. |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating lung cancer
|
|
WO2025117869A1
(en)
|
2023-11-29 |
2025-06-05 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating recurrent ovarian cancer and endometrial cancer with bispecific anti-muc16 x anti-cd28 antibodies in combination with anti-pd-1 antibodies or bispecific anti-muc16 x anti-cd3 antibodies
|
|
WO2025117889A2
(en)
|
2023-11-30 |
2025-06-05 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer by administering a combination therapy including a neoadjuvant pd-1 inhibitor
|
|
WO2025114541A1
(en)
|
2023-11-30 |
2025-06-05 |
Genmab A/S |
Antibodies capable of binding to ox40 in combination therapy
|
|
WO2025122614A1
(en)
|
2023-12-05 |
2025-06-12 |
Regeneron Pharmaceuticals, Inc. |
Il18 receptor agonists and methods of use thereof
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025128652A1
(en)
|
2023-12-12 |
2025-06-19 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating endometrial cancer with bispecific anti-muc16 x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
|
|
WO2025145207A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg-depleting agent
|
|
WO2025155607A1
(en)
|
2024-01-16 |
2025-07-24 |
Genentech, Inc. |
Methods of treating urothelial carcinoma with a pd-1 axis binding antagonist and an rna vaccine
|
|
WO2025166281A1
(en)
|
2024-02-01 |
2025-08-07 |
Regeneron Pharmaceuticals, Inc. |
Platform for charge-detection mass spectrometry analysis of aavs
|
|
WO2025174933A1
(en)
|
2024-02-14 |
2025-08-21 |
Genentech, Inc. |
Methods for treatment of pancreatic cancer with anti-pd-l1 ab, anti-tigit ab, gemcitabine and nab-placlitaxel
|
|
WO2025175164A1
(en)
|
2024-02-16 |
2025-08-21 |
Regeneron Pharmaceuticals, Inc. |
Methods of producing concentrated formulated drug substances comprising proteins, and concentrated formulated drug substance made by the methods
|
|
US20250361320A1
(en)
|
2024-02-27 |
2025-11-27 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
EP4658320A1
(en)
|
2024-02-27 |
2025-12-10 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|
|
WO2025194043A1
(en)
|
2024-03-15 |
2025-09-18 |
Regeneron Pharmaceuticals, Inc. |
Polysorbate and polyoxyethylene sorbitan as excipients for stable protein formulations
|
|
WO2025199243A1
(en)
|
2024-03-20 |
2025-09-25 |
Regeneron Pharmaceuticals, Inc. |
Trivalent multispecific binding molecules and methods of use thereof
|
|
WO2025226695A1
(en)
|
2024-04-23 |
2025-10-30 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
WO2025232879A1
(en)
|
2024-05-10 |
2025-11-13 |
Cytocares (Shanghai) Inc. |
Anti-lilrb2 monospecific and bispecific antibody constructs and uses thereof
|
|
WO2025245489A1
(en)
|
2024-05-24 |
2025-11-27 |
Bristol-Myers Squibb Company |
Treatment of tumors in subjects having fgl-1 positive samples
|