BR112023024984A2 - Tampão de amostra de eletroforese aquosa, método para identificar contaminantes ou impurezas em uma amostra de droga proteica, e, kit - Google Patents

Tampão de amostra de eletroforese aquosa, método para identificar contaminantes ou impurezas em uma amostra de droga proteica, e, kit

Info

Publication number
BR112023024984A2
BR112023024984A2 BR112023024984A BR112023024984A BR112023024984A2 BR 112023024984 A2 BR112023024984 A2 BR 112023024984A2 BR 112023024984 A BR112023024984 A BR 112023024984A BR 112023024984 A BR112023024984 A BR 112023024984A BR 112023024984 A2 BR112023024984 A2 BR 112023024984A2
Authority
BR
Brazil
Prior art keywords
protein drug
impurities
kit
sample
identifying contaminants
Prior art date
Application number
BR112023024984A
Other languages
English (en)
Inventor
Gabriel Carreau
Jeffrey Schneiderheinze
M Nall Nicole
Timothy Riehlman
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/335,756 external-priority patent/US20210293749A1/en
Priority claimed from US17/368,377 external-priority patent/US20210333235A1/en
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of BR112023024984A2 publication Critical patent/BR112023024984A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44747—Composition of gel or of carrier mixture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/24—Extraction; Separation; Purification by electrochemical means
    • C07K1/26—Electrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus

Abstract

tampão de amostra de eletroforese aquosa, método para identificar contaminantes ou impurezas em uma amostra de droga proteica, e, kit. são fornecidos ensaios e reagentes de eletroforese capilar microchip (mce) para avaliar pureza e identificar impurezas em amostras de produto de droga de proteína. são fornecidos métodos para analisar analitos em uma amostra de droga de proteína.
BR112023024984A 2021-06-01 2022-06-01 Tampão de amostra de eletroforese aquosa, método para identificar contaminantes ou impurezas em uma amostra de droga proteica, e, kit BR112023024984A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17/335,756 US20210293749A1 (en) 2018-03-19 2021-06-01 Microchip capillary electrophoresis assays and reagents
US17/368,377 US20210333235A1 (en) 2018-03-19 2021-07-06 Microchip capillary electrophoresis assays and reagents
PCT/US2022/031738 WO2022256383A1 (en) 2021-06-01 2022-06-01 Micropchip capillary electrophoresis assays and reagents

Publications (1)

Publication Number Publication Date
BR112023024984A2 true BR112023024984A2 (pt) 2024-02-20

Family

ID=82608737

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023024984A BR112023024984A2 (pt) 2021-06-01 2022-06-01 Tampão de amostra de eletroforese aquosa, método para identificar contaminantes ou impurezas em uma amostra de droga proteica, e, kit

Country Status (8)

Country Link
EP (1) EP4348234A1 (pt)
KR (1) KR20240015646A (pt)
AU (1) AU2022286340A1 (pt)
BR (1) BR112023024984A2 (pt)
CA (1) CA3220848A1 (pt)
IL (1) IL308864A (pt)
TW (1) TW202314240A (pt)
WO (1) WO2022256383A1 (pt)

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Also Published As

Publication number Publication date
KR20240015646A (ko) 2024-02-05
TW202314240A (zh) 2023-04-01
CA3220848A1 (en) 2022-12-08
IL308864A (en) 2024-01-01
WO2022256383A1 (en) 2022-12-08
EP4348234A1 (en) 2024-04-10
AU2022286340A1 (en) 2024-01-04

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