BR112019006930A2 - dispositivos e métodos para análise de amostra - Google Patents

dispositivos e métodos para análise de amostra

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Publication number
BR112019006930A2
BR112019006930A2 BR112019006930A BR112019006930A BR112019006930A2 BR 112019006930 A2 BR112019006930 A2 BR 112019006930A2 BR 112019006930 A BR112019006930 A BR 112019006930A BR 112019006930 A BR112019006930 A BR 112019006930A BR 112019006930 A2 BR112019006930 A2 BR 112019006930A2
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Brazil
Prior art keywords
nanopore
binding member
methods
devices
analyte
Prior art date
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BR112019006930A
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English (en)
Inventor
Davis Graham
B Huff Jeffrey
A Hayden Mark
Gershtein Sergey
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Abbott Lab
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Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BR112019006930A2 publication Critical patent/BR112019006930A2/pt

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    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
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    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
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Abstract

métodos, dispositivos, e sistemas para análise de analito usando um nanoporo são divulgados. os métodos, dispositivos, e sistemas utilizam um primeiro e um segundo membro de ligação de modo que cada um especificamente se ligue a um analito em uma amostra biológica. o método inclui ainda detectar e/ou contar um rótulo clivável ligado ao segundo membro de ligação e correlacionar a presença e/ou o número de rótulos à presença e/ou concentração do analito. a detecção e/ou a contagem podem ser realizadas deslocando-se o rótulo/segundo membro de ligação através de um nanoporo. também fornecidos aqui são instrumentos que são programados para operar um cartucho que inclui um arranjo de eletrodos para acionar uma gotícula e inclui ainda uma região de sensibilização de espécie eletroquímica. o instrumento pode ser usado para analisar uma amostra em um cartucho que inclui um arranjo de eletrodos para acionar uma gotícula e inclui ainda uma camada de nanoporo para detectar o deslocamento de um rótulo/segundo membro de ligação através de nanoporo.
BR112019006930A 2016-10-05 2017-10-05 dispositivos e métodos para análise de amostra BR112019006930A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662404722P 2016-10-05 2016-10-05
US201662424996P 2016-11-21 2016-11-21
PCT/US2017/055425 WO2018067878A1 (en) 2016-10-05 2017-10-05 Devices and methods for sample analysis

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BR112019006930A2 true BR112019006930A2 (pt) 2019-07-02

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US (2) US11016053B2 (pt)
EP (1) EP3523640B1 (pt)
JP (2) JP2020502478A (pt)
CN (1) CN109863391B (pt)
BR (1) BR112019006930A2 (pt)
WO (1) WO2018067878A1 (pt)
ZA (1) ZA201901985B (pt)

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