CN105997305A - 用于使瓣膜假体与组织相接合的方法和装置 - Google Patents
用于使瓣膜假体与组织相接合的方法和装置 Download PDFInfo
- Publication number
- CN105997305A CN105997305A CN201610543000.5A CN201610543000A CN105997305A CN 105997305 A CN105997305 A CN 105997305A CN 201610543000 A CN201610543000 A CN 201610543000A CN 105997305 A CN105997305 A CN 105997305A
- Authority
- CN
- China
- Prior art keywords
- auricle
- valve
- skirt section
- ventricle
- atrium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2403—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with pivoting rigid closure members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2436—Deployment by retracting a sheath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2475—Venous valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
- A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0034—D-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
本发明公开一种假体瓣膜,其包含自扩张框架,该框架包括形成带凸缘的区域的自扩张心房裙部、自扩张心室裙部以及与该心室裙部相耦合的第一自扩张耳片。由心房裙部的外表面、心室裙部的外表面和第一耳片的内表面所界定的区域形成用于接纳瓣膜小叶的容器。该容器具有用于接纳瓣膜小叶的窗口,所述窗口由凸缘的边缘与第一耳片的尖端之间的间隙所限定。当第一耳片的尖端不受约束且第一耳片的基部至少部分地受约束时,所述间隙最大。当第一耳片的尖端及其基部不受约束时,所述间隙最小。
Description
本申请是申请日为2013年2月13日、申请号为201380017320.1、(国际申请号PCT/CA2013/000129)发明名称为“用于使瓣膜假体与组织相接合的方法和装置”的发明专利申请的分案申请。
交叉引用
本申请为提交于2012年2月14日的美国临时专利申请No.61/598,626(代理人案卷号42194-705.101)的非临时申请,并要求其权益;上述申请的全部内容通过引用并入于此。
本申请涉及提交于2011年4月28日的美国专利申请No.13/096,572(代理人案卷号42194-703.201);和提交于2012年11月16日的美国专利申请No.13/679,920(代理人案卷号42194-704.201),这些申请的全部内容通过引用并入于此。
发明背景
1.发明领域。本发明总体上涉及医疗装置和方法,并且更具体地涉及治疗瓣膜功能不全,如二尖瓣关闭不全,亦称为二尖瓣反流。瓣膜功能不全(亦称为反流)的一种可能的疗法是使用通过传统的外科植入法递送或者通过创伤较小的经皮导管或微创经心尖法递送的假体瓣膜。
脊椎动物的心脏分为四个腔室,并带有四个瓣膜(二尖瓣、主动脉瓣、肺动脉瓣和三尖瓣),它们确保由心脏泵送的血液在向前的方向上流过心血管系统。健康心脏的二尖瓣阻止血液从心脏的左心室向左心房中回流,且该二尖瓣包括当左心室收缩时闭合的两片柔性小叶(前小叶和后小叶)。所述小叶附接到纤维环,且它们的自由边通过瓣下腱索系至左心室中的乳头肌以防止它们在左心室收缩过程中脱垂入左心房中。
各种心脏疾病或退行性病变可导致二尖瓣器的这些部分中的任何部分的功能障碍,导致二尖瓣变得异常缩窄或扩张,或者允许血液从左心室回漏(即,反流)至左心房中。任何这样的损伤都会危害心脏的完好性,并且可能会使人衰弱或危及生命。
因此,已开发出许多外科方法和装置来治疗二尖瓣功能障碍,包括用于替换、修复或重塑天然二尖瓣器的心内直视外科技术,以及用以改变天然二尖瓣解剖结构的诸如瓣环成形术环等各种假体装置的外科植入。近来,已开发出用于递送置换二尖瓣组装件的创伤较小的经导管技术。在此类技术中,假体瓣膜一般以卷曲状态安装在柔性导管的末端并经患者的血管或身体推进,直至该瓣膜抵达植入部位。继而,假体瓣膜在有缺陷的天然瓣膜的部位处扩张至其功能尺寸。
尽管这些装置和方法是针对瓣膜功能不全的有效疗法,但它们可能难以递送,制造昂贵,或者可能不适用于所有患者。此外,这些装置通常通过接合诸如天然瓣膜小叶等组织而锚固至天然瓣膜中。捕获移动的瓣膜小叶可能具有挑战性。因此,期望提供用于治疗瓣膜功能不全、比如治疗二尖瓣功能不全的改进的装置和方法。期望这些装置能容易地接合组织并将装置锚固在治疗部位上。下文公开的装置和方法将会满足这些目标中的至少一些目标。
2.背景技术说明。举例而言,公开内容通过引用并入于此的PCT国际专利号PCT/US2008/0544 0(以PCT国际公开号WO2008/103722公开)描述了一种经导管二尖瓣假体,其包括:弹性环;多个小叶膜,它们与所述环相对地安装以允许血液沿一个方向从其中流过;以及多个组织接合定位元件,它们相对于所述环可移动地安装且尺寸设定为包握心脏瓣膜环、心脏瓣膜小叶和/或心脏壁的解剖结构。每个定位元件限定相应的近端、中间和远端组织接合区,它们被协同地配置和设定尺寸以便同时接合解剖结构的组织的单独的对应区域,且所述定位元件可包括相应的第一、第二和第三细长组织穿刺元件。瓣膜假体还可包括相对于弹性环安装的裙部,用于密封瓣膜假体的周边以防血液在瓣膜假体周围逆流。
公开内容通过引用并入于此的PCT国际专利号PCT/US2009/041754(以PCT国际公开号WO2009/134701公开)描述了一种假体二尖瓣组装件,其包括具有张开的上端和渐缩部以适配天然二尖瓣轮廓的锚固件或外支撑框架,以及安装在其中的基于组织的单向瓣膜。该组装件适于径向向外扩张并与天然心脏组织相接触以形成压配合,且该组装件还包括张紧构件,该张紧构件将瓣膜组装件的小叶锚固至心脏上的合适位置以发挥假体腱索的功能。
还已知利用卡爪结构将假体附接到心脏的假体二尖瓣组装件(例如,见Hermann等人的美国专利申请公开号US2007/0016286,其公开内容通过引用并入于此),这样的假体二尖瓣组装件依赖于轴向而非径向夹持力的施加,以便促进假体相对于天然解剖结构的自定位和自锚固。
作为二尖瓣反流的疗法而提出的另一方法是外科双孔成形(bow tie)法,其最近已适合基于微创导管的治疗,其中使用植入物将瓣膜小叶夹在一起。该手术更充分地公开于科学和专利文献中,诸如公开于St.Goar等人的美国专利号6,629,534中,该文献的全部内容通过引用并入本文。
其他相关的公开文献包括Carpentier等人的美国专利公开号2011/0015731和Lane等人的WO 2011137531。虽然这些装置和方法中的一些装置和方法是有前途的,但仍然存在对于将会进一步允许更精确地定位假体瓣膜并且还将会更牢固地将瓣膜锚固到位的改进的装置和方法的需求。本文所公开的示例性实施方式将会满足这些目标中的至少一些目标。
发明内容
本发明总体上涉及医疗装置和方法,并且更具体地涉及用于治疗二尖瓣反流的假体瓣膜。尽管本公开着眼于治疗二尖瓣反流的假体瓣膜的使用,但并不旨在仅限于此。本文所公开的假体瓣膜还可用于治疗其他身体瓣膜,包括其他心脏瓣膜或静脉瓣膜。示例心脏瓣膜包括主动脉瓣、三尖瓣或肺动脉瓣。本领域技术人员还将会认识到,还可以用本文所公开的装置和方法来治疗其他身体瓣膜。
在本发明的第一方面,一种假体瓣膜包括自扩张框架,该自扩张框架具有上端、下端和其间的中段。框架具有扩张配置和收缩配置。收缩配置适于被递送到患者的心脏,而扩张配置适于将自扩张框架锚固在患者的心脏中。框架包括与所述上端相邻的自扩张心房裙部、与所述下端相邻的自扩张心室裙部以及与所述下端相邻并与心室裙部相耦合的第一自扩张耳片。心房裙部在自扩张之后形成带凸缘的区域,并配置用于将自扩张框架锚固到心脏的心房表面。带凸缘的区域还包括凸缘的边缘。心室裙部在自扩张之后将自扩张框架锚固到心脏的心室表面。第一耳片与心室裙部相耦合,并具有尖端。当从第一耳片移除约束时,其径向自扩张。由心房裙部的外表面、心室裙部的外表面和第一耳片的内表面所界定的区域形成容器。该容器适于接纳瓣膜小叶。容器中的窗口适于接纳瓣膜小叶,并由凸缘的边缘与第一耳片的尖端之间的间隙所限定。当第一耳片的尖端不受约束且第一耳片的基部至少部分地受约束时,间隙最大。当第一耳片的尖端不受约束且第一耳片的基部也不受约束时,间隙最小。
当间隙最大时,窗口可适于在容器中接纳瓣膜小叶,而当间隙最小时,容器可适于接合瓣膜小叶,并向其锚固假体瓣膜。当从约束中释放第一耳片的基部时,第一耳片的尖端可朝向凸缘的边缘移动。耳片的尖端可适于接合纤维三角区或者前二尖瓣小叶或后二尖瓣小叶。角α可由第一耳片的内表面和心室裙部的外表面所限定。当从约束中释放第一耳片的基部且第一耳片的尖端也不受约束时,角α可变得更尖锐。当第一耳片的尖端不受约束且第一耳片的基部至少部分地受约束时,可使角α最大化。
假体可进一步包括连合杆,该连合杆与自扩张框架相耦合并且具有径向向内延伸的末端。角β可由连合杆的外表面和心室裙部的内表面所限定。当第一耳片的基部至少部分地受约束且第一耳片的尖端不受约束时,可使角β最小化。当第一耳片的基部不受约束且第一耳片的尖端不受约束时,可使角β最大化。连合杆可适于在第一耳片的基部和第一耳片的尖端不受约束之后保持耦合至递送导管。可以至少部分地在自扩张框架上安置覆盖物,并且该覆盖物可促进组织长入。覆盖物可包括织物、组织或聚合物。
在一些实施方式中,心房裙部可先于耳片扩张,并且因此在耳片将假体心脏瓣膜锚固到瓣膜小叶之前,心房裙部可将假体心脏瓣膜锚固到心房。耳片可扩张至横向于假体心脏瓣膜的纵轴线的位置,随后扩张至更加垂直定向的位置,并且该位置可更平行于或基本上平行于假体心脏瓣膜的纵轴线。
在本发明的另一方面,一种用于将假体瓣膜锚固到具有瓣膜小叶的心脏瓣膜的方法包括提供具有外鞘套的递送系统,以及提供假体瓣膜。假体瓣膜由递送系统所携带,并且假体瓣膜包括心房裙部、心室裙部和耦合至心室裙部的第一耳片。心房裙部的外表面、心室裙部的外表面以及第一耳片的内表面形成小叶容器。该小叶容器具有用于接纳瓣膜小叶的窗口。该窗口由心房裙部的边缘与第一耳片的尖端之间的间隙所限定。该方法还包括将假体瓣膜定位在与心脏瓣膜相邻之处,使心房裙部自扩张成与心脏瓣膜的心房表面相接合,以及使心室裙部自扩张成与心脏瓣膜的心室表面相接合。从所述第一耳片的一部分移除约束,从而允许第一耳片的尖端径向向外扩张。瓣膜小叶通过窗口被接纳,并进入小叶容器,并且窗口的部分或全部关闭将瓣膜小叶与小叶容器相接合,从而将假体瓣膜锚固到瓣膜小叶。
将假体瓣膜定位在与心脏瓣膜相邻之处可以包括假体瓣膜向心脏瓣膜的经中隔或经心尖递送。使心房裙部自扩张可以包括缩回外鞘套,从而从其移除约束。使心房裙部自扩张可以包括形成与心脏瓣膜的心房表面相接合的凸缘,从而将假体瓣膜锚固于其上。使心室裙部自扩张可以包括缩回外鞘套,从而从其移除约束。使心室裙部自扩张还可包括扩张心室裙部使之与心脏瓣膜的心室表面相接合,从而将假体瓣膜锚固于其上。从第一耳片的一部分移除约束可以包括从其缩回外鞘套。至少部分地关闭窗口可以包括进一步缩回外鞘套,以从第一耳片的基部移除约束,从而允许基部径向向外扩张,以使第一耳片的尖端朝向心房裙部的边缘移动。瓣膜小叶可包括前二尖瓣小叶,并且该方法可进一步包括使第一耳片的尖端与二尖瓣的纤维三角区相接合。假体瓣膜还可具有第二前耳片,该第二前耳片也具有接合纤维三角区的相对一侧的尖端。瓣膜小叶可包括后二尖瓣小叶,并且接合瓣膜小叶可以包括接合后二尖瓣小叶。
在本发明的又一方面,一种用于展开假体瓣膜的系统包括假体心脏瓣膜,该假体心脏瓣膜具有心房裙部、心室裙部以及耦合至心室裙部的耳片。该系统还包括具有外鞘套的递送系统,并且假体心脏瓣膜由该递送系统所携带。外鞘套包括位于外鞘套上与其远侧末端相邻的凸轮。外鞘套的部分回缩从心房裙部和心室裙部释放约束,从而允许其自扩张。外鞘套的进一步回缩从耳片释放约束,从而允许耳片的尖端径向向外自扩张,在心房裙部的边缘与耳片的尖端之间形成窗口。在凸轮保持与耳片的基部部分相接合的同时,尖端自扩张以使得窗口打开至其最大尺寸。外鞘套的进一步回缩使凸轮从耳片的基部部分脱离,从而从其释放约束。这允许耳片的基部径向向外扩张,并且耳片的尖端朝向心房裙部的边缘移动,从而至少部分地关闭窗口。
凸轮可包括安置在外鞘套的内表面上的环形凸缘。外鞘套可包括管腔,并且假体心脏瓣膜可安置在其中。窗口可适于在打开时接纳瓣膜小叶。在窗口至少部分地关闭之后,假体瓣膜可锚固到瓣膜小叶。该系统可进一步包括至少部分地安置于假体心脏瓣膜上的覆盖物。该覆盖物可促进组织长入。覆盖物可包括织物、组织或聚合物。耳片的尖端可适于接合纤维三角区。耳片可适于接合前二尖瓣小叶或后二尖瓣小叶。
在本发明的另一方面,一种用于将假体瓣膜锚固到具有瓣膜小叶的心脏瓣膜的方法包括提供包含心房裙部、心室裙部以及耦合至心室裙部的耳片的假体心脏瓣膜,并且还提供带有外鞘套的递送系统。外鞘套具有与其远侧末端相邻的凸轮,并且其中假体心脏瓣膜由该递送系统所携带。该方法还包括使心房裙部和心室裙部自扩张,以及使耳片自扩张以使耳片的尖端径向向外扩张,并由此在心房裙部的边缘与耳片的尖端之间形成窗口。将窗口打开至其最大尺寸,并在该窗口中接纳瓣膜小叶。当耳片的尖端朝向心房裙部的边缘移动时,耳片的基部部分径向向外自扩张并且窗口至少部分地关闭。
使心房裙部和心室裙部自扩张可以包括缩回外鞘套,从而从其释放约束。使心房裙部自扩张可允许心房裙部自扩张成与心脏瓣膜的心房表面相接合。使心室裙部自扩张可允许心室裙部自扩张成与心脏瓣膜的心室表面相接合。使耳片自扩张可以包括缩回外鞘套,从而从其释放约束。打开窗口可以包括保持凸轮与耳片的基部部分的接合,以使耳片的尖端独立于基部而自扩张。使基部部分自扩张可以包括使凸轮从耳片的基部部分脱离,从而从其释放约束。瓣膜小叶可包括前二尖瓣小叶,并且该方法可进一步包括使耳片的尖端与二尖瓣的纤维三角区相接合。瓣膜小叶可包括后二尖瓣小叶,并且该方法可进一步包括使耳片与后二尖瓣小叶相接合。
在本发明的又一方面,一种用于展开假体瓣膜的系统包括假体心脏瓣膜,该假体心脏瓣膜包括心房裙部、心室裙部以及耦合至心室裙部的耳片。该系统还包括具有外鞘套和推动器元件的递送系统。假体心脏瓣膜由递送系统所携带,并且推动器元件可滑动地安置在外鞘套之下。外鞘套的部分回缩从心房裙部和心室裙部释放约束,从而允许其自扩张。外鞘套的进一步回缩从耳片释放约束,从而允许耳片的尖端径向向外自扩张,在心房裙部的边缘与耳片的尖端之间形成窗口。耳片的基部部分保持受外鞘套的约束,并且推动器元件与基部部分相接合的致动对耳片的尖端加以致动,以将窗口打开至其最大尺寸。外鞘套的进一步回缩或推动器元件的进一步致动从耳片的基部部分移除约束,从而至少部分地关闭窗口。
当从基部部分释放约束时,其可径向向外自扩张,并且耳片的尖端可朝向心房裙部的边缘移动以关闭窗口。可以至少部分地在假体心脏瓣膜上安置覆盖物,以便促进组织长入。覆盖物可包括织物、组织或聚合物。耳片可适于接合纤维三角区,或者耳片可适于接合前二尖瓣小叶或后二尖瓣小叶。
在本发明的另一方面,一种用于将假体瓣膜锚固到具有瓣膜小叶的心脏瓣膜的方法包括提供假体心脏瓣膜和提供递送系统。该心脏瓣膜包括心房裙部、心室裙部以及耦合至心室裙部的耳片。递送系统包括外鞘套和推动器元件,其中所述心脏瓣膜由该递送系统所携带,并且推动器元件可滑动地安置在外鞘套之下。该方法还包括使心房裙部自扩张成与心脏瓣膜的心房表面相接合,使心室裙部自扩张成与心脏瓣膜的心室表面相接合,以及使耳片自扩张以使耳片的尖端径向向外扩张以便在心房裙部的边缘与耳片的尖端之间形成窗口。在耳片的基部部分保持受外鞘套的约束的同时,所述方法包括将窗口打开至其最大尺寸,并将瓣膜小叶接纳到窗口之中。继而关闭窗口。
使心房裙部自扩张可以包括缩回外鞘套,以从其移除约束。使心室裙部自扩张可以包括缩回外鞘套,以从其移除约束。使耳片自扩张可以包括缩回外鞘套,以从其移除约束。打开窗口可以包括对推动器元件加以致动以使之与基部部分相接合,从而将尖端移离心房裙部的边缘。关闭窗口可以包括外鞘套的进一步回缩,以从基部部分移除约束,从而允许基部部分径向向外扩张,以及允许尖端朝向心房裙部的边缘移动。关闭窗口可以包括使推动器元件从基部部分脱离,从而允许基部部分返回到无偏斜位置。无偏斜位置可径向向外远离递送系统。关闭窗口可以包括用推动器元件将基部部分推出外鞘套,从而允许基部部分径向向外扩张,以及允许尖端朝向心房裙部的边缘移动。瓣膜小叶可包括前二尖瓣小叶,并且所述方法可进一步包括使耳片的尖端与二尖瓣的纤维三角区相接合。瓣膜小叶可包括后二尖瓣小叶,并且所述方法可进一步包括使耳片与后二尖瓣小叶相接合。
在涉及附图的以下描述中进一步详细地描述这些实施方式和其他实施方式。
援引并入
本说明书中所提及的所有出版物、专利和专利申请均通过引用并入本文,程度如同具体地和个别地指出要通过引用而并入每一单个出版物、专利或专利申请。
附图说明
本发明的新颖特征在随附权利要求书中具体阐述。通过参考以下对其中利用到本发明原理的示例说明性实施方式加以阐述的详细描述和附图,将会对本发明的特征和优点获得更好的理解;在附图中:
图1是心脏的左心室的示意图,图中用箭头示出心缩期的血液流动。
图2是心脏的左心室的示意图,其具有二尖瓣中的脱垂小叶。
图3是患有心肌病的患者体内心脏的示意图,其中心脏扩张且小叶不相接。
图3A示出瓣膜小叶的正常闭合。
图3B示出瓣膜小叶的异常闭合。
图4图示了具有受损的乳头肌的心脏左心室中的二尖瓣反流。
图5A-图5B图示了二尖瓣的解剖结构。
图6图示了假体心脏瓣膜中的无覆盖框架的示例性实施方式,其中所述框架被展平和铺开。
图7图示了假体心脏瓣膜中的无覆盖框架的另一示例性实施方式,其中所述框架被展平和铺开。
图8图示了假体心脏瓣膜中的无覆盖框架的又一示例性实施方式,其中所述框架被展平和铺开。
图9A图示了假体心脏瓣膜中的无覆盖框架在其扩张之后的透视图。
图9B图示了图9A中的实施方式的俯视图。
图10图示了图9A的框架具有覆盖物从而形成假体心脏瓣膜。
图11A-图11D图示了用于经心尖递送假体心脏瓣膜的递送系统的示例性实施方式。
图12A-图12L图示了植入假体心脏瓣膜的示例性方法。
图13A-图13L图示了植入假体心脏瓣膜的另一示例性方法。
图14图示了假体瓣膜耳片与瓣膜小叶的接合。
图15A-图15B图示了从递送系统释放假体瓣膜。
图16A-图16B图示了从递送系统释放假体瓣膜。
图17A-图17B示意性地图示了从递送系统展开假体瓣膜。
图18A-图18B图示了假体瓣膜和控制假体瓣膜展开的递送系统的实施方式。
图19A-图19B图示了假体瓣膜和控制假体瓣膜展开的递送系统的另一实施方式。
图20A-图20B图示了假体瓣膜和控制假体瓣膜展开的递送系统的又一实施方式。
具体实施方式
现将参考附图来描述公开的装置、递送系统和方法的具体实施方式。这些详细描述中的内容并不旨在暗示任何特定组件、特征或步骤对于本发明而言是不可或缺的。
心脏解剖结构。图1中图示了处于心缩期的正常心脏H的左心室LV。左心室LV正在收缩并且血液在箭头方向上通过主动脉瓣AV、即三尖瓣向外流动。由于二尖瓣被构造成当左心室中的压强高于左心房LA中的压强时阻止回流的“止回阀”,因此阻止了通过二尖瓣MV的血液回流或“反流”。如图1中所示,二尖瓣MV包括一对小叶,所述小叶具有均匀接触以便闭合的自由边FE。小叶LF的相对端沿着被称为环AN的环形区附接到周围的心脏结构。小叶LF的自由边FE通过腱索CT(在本文也称为索)紧固至左心室LV的下部,该腱索包括紧固在每个瓣膜小叶LF的底面上的多个分支腱。索CT转而附接至从左心室下部和室间隔IVS向上延伸的乳头肌PM。
现参考图2-图4,心脏中的若干结构缺陷可能导致二尖瓣反流。如图2中所示,断裂的腱索RCT可能因经由腱索传递至小叶的张力不足而导致瓣膜小叶LF2脱垂。尽管另一小叶LF1保持正常外形,但两个瓣膜小叶不能正确地接触,因而会发生如箭头所示的从左心室LV向左心房LA中的泄漏。
反流还发生在患有心肌病的患者身上,其中,心脏如图3中所示地扩张,而增大的尺寸阻止了瓣膜小叶LF正确接触。心脏的增大导致二尖瓣环变大,使得自由边FE无法在心缩期相接触。如图3A中所示,前小叶和后小叶的自由边正常情况下沿着接合线C接触,但是如图3B中所示,在患有心肌病的患者体内可能留有显著的间隙G。
二尖瓣反流还可能在患有缺血性心脏病的患者身上发生,其中如图4中所示,乳头肌PM的功能受损。当左心室LV在心缩期收缩时,乳头肌PM不能充分收缩来实现正确的闭合。从而如图所示,小叶LF1和LF2脱垂。如箭头所示,再次发生从左心室LV向左心房LA的泄漏。
图5A更清楚地图示了二尖瓣MV的解剖结构,其为具有前侧ANT和后侧POST的二叶瓣。该瓣膜包括前(主动脉)小叶AL和后(壁)小叶PL。腱索CT将瓣膜小叶AL、PL与前外侧乳头肌ALPM和后内侧乳头肌PMPM相耦合。瓣膜小叶AL、PL沿着被称为前外侧连合部ALC和后内侧连合部PMC的线彼此接合。环AN包围瓣膜小叶,并且毗邻所述环的前部、位于前小叶的相对两侧上的两个区域被称为左纤维三角区LFT和右纤维三角区RFT。这些区域大体上以实线三角形标示。图5B更清楚地图示了左纤维三角区LFT和右纤维三角区RFT。
尽管已经提出了各种外科技术以及植入式装置,并且它们看起来是针对二尖瓣反流的有前途的疗法,但外科方法可能需要漫长的恢复期,而植入式装置具有不尽相同的临床结果。因此,仍然需要用于治疗二尖瓣反流的改进的装置和方法。尽管本文公开的实施方式针对用于治疗二尖瓣反流的植入式假体二尖瓣,但是本领域技术人员将会理解这并不旨在仅限于此,并且本文所公开的装置和方法还可用于治疗其他心脏瓣膜,诸如三尖瓣、主动脉瓣、肺动脉瓣等,以及体内的其他瓣膜,诸如静脉瓣膜以及肠胃系统和呼吸系统中的瓣膜,以及其他解剖瓣膜。
假体瓣膜。已通过外科手术将假体瓣膜植入在心脏之中作为对二尖瓣反流的治疗。这些瓣膜中的一些瓣膜是诸如猪瓣膜等取自动物的瓣膜、由刚性组件制造而成的其他机械瓣膜,以及由心包组织制造而成的其他瓣膜。近来,微创技术已被用于向心脏递送假体瓣膜。这些瓣膜通常包括用于将瓣膜紧固至患者心脏的锚固件,以及瓣膜机构——刚性瓣膜、带有动物组织的瓣膜,或者它们的组合。
假体瓣膜一旦被植入,就会接替功能失常的天然瓣膜,从而减小或消除瓣膜功能不全。尽管这些瓣膜中的一些瓣膜看起来是有效的,但仍然需要改进的瓣膜。在天然解剖结构中定位和锚固假体瓣膜仍是一个挑战。以下公开了克服与现有假体瓣膜相关联的一些挑战的假体瓣膜、用于该假体瓣膜的递送系统以及递送该瓣膜的方法的示例性实施方式。
图6图示了处于收缩配置下的假体心脏瓣膜的示例性实施方式。已经从框架移除覆盖物(例如,织物或组织),以允许观察下面的框架600。该框架已被铺开和展平。假体瓣膜框架600具有心房区606、环形区608和心室区610。框架600由多个互连的支柱所形成,所述支柱形成一系列凸峰和凹谷,所述凸峰和凹谷可相对于彼此扩张和收缩从而允许将框架以收缩配置装载到递送导管上,并继而使其在靶治疗部位处径向扩张以供植入。优选实施方式为自扩张式,并且可使用超弹性镍钛诺(super elastic nitinol)或其他自扩张材料制成。还可以使用在高于转变温度时弹开的形状记忆合金,并且还可以使用可扩张构件以在需要塑性变形(例如,球囊扩张)来敞开框架时扩张该框架。
心房区606具有裙部616,该裙部616包括形成一系列凸峰和凹谷的多个互连的支柱。在该区域中,所述支柱相对于彼此偏斜,并且因此,所产生的单元图案具有一个扩大的末端,而相对的末端渐缩成较小的末端。在优选实施方式中,心房裙部的前部不像后部那样具有带凸缘的区域,因此心房区的前部602可具有比后区604更短的支柱。因此,所述前部中的凸峰和凹谷从心房区的其余后部中的凸峰和凹谷轴向偏移。由于这防止了心房裙部的前部中的支柱向上突出而潜在地碰撞左心房并导致穿孔,因此可能是有利的。此外,缩短的支柱和偏移的凸峰与凹谷形成对准元件614,该对准元件614可协助医师对假体瓣膜向二尖瓣的递送以及在假体瓣膜的扩张之前的假体瓣膜的对准加以可视化。可选的不透射线标记614a安置在偏移的凸峰和凹谷的任一侧上,并且进一步帮助在瓣膜植入期间的可视化。心房区优选地自扩张成圆柱形,或者其可具有D形横截面,其中前部602基本上是平坦的,而后部604为圆柱形。这允许心房裙部吻合天然二尖瓣的解剖结构,从而防止主动脉的阻塞。此外,心房裙部还可形成为使得在扩张时该裙部向外张开并形成可抵靠二尖瓣的上表面的凸缘。带凸缘的区域优选地沿着心房裙部的后部,并且心房裙部的前部保持无凸缘,也有助于防止主动脉碰撞。或者,所述凸缘可在整个心房裙部周围延伸。心房区用连接支柱连接至相邻的环形区608,所述连接支柱优选地是直线的,并且基本上平行于框架的纵轴线。
环形区608也包含多个轴向定向并互连的支柱,所述支柱形成允许径向扩张的凸峰和凹谷。所述支柱优选地彼此平行,并且平行于框架的纵轴线。环形区也可为自扩张式,并且扩张成圆柱形,或者更优选地,环形区可扩张以具有如上文关于心房区所述的D形横截面。因此,环形区可类似地具有平坦的前部和圆柱形的后部。当递送时,环形区与二尖瓣环对准并且扩张成与二尖瓣环相接合。连接器支柱将环形区与心室区610接合起来。
心室区610也包括形成凸峰和凹谷的多个互连支柱。此外,心室区中的支柱形成小叶连合部613,所述小叶连合部613覆盖有织物、心包组织或其他材料,以形成假体瓣膜小叶。连合部中的孔允许向其附接缝合线。心室区中的支柱还形成向外扩张以接合前二尖瓣小叶和后二尖瓣小叶的心室裙部628,并且心室区中的支柱还形成前耳片624和后耳片630。前耳片被设计用于将前二尖瓣小叶捕获在前耳片的内表面与心室裙部的外表面之间。还可将任何相邻的腱索捕获在其间。另外,前耳片的尖端接合位于二尖瓣的前部上的纤维三角区,所述纤维三角区一个位于左侧,一个位于右侧。后耳片类似地将后二尖瓣小叶连同任何相邻的腱索一起捕获在后耳片的内表面与心室裙部的外表面之间。这将在下文中更详细地描述。
通过沿着框架控制前耳片或后耳片的支柱长度或轴向位置,可以控制耳片的展开。因此,在本示例性实施方式中,由于前耳片624和后耳片630中的支柱的长度及其沿着框架的相对位置彼此相同,因此当从耳片缩回约束鞘套时,前耳片和后耳片将会部分地一起向外弹出。随着约束鞘套被进一步缩回,前耳片的其余部分将会径向向外自扩张。约束鞘套的进一步回缩继而允许后耳片的其余部分完成其径向扩张,并且最终心室裙部将会径向向外扩张。虽然后耳片和心室裙部的支柱长度和轴向位置相似,但内部支柱将心室裙部与连合部相连接,而这稍微延迟了心室裙部的扩张,因而后耳片在心室裙部之前完成扩张。使用这样的假体瓣膜展开顺序可以允许更准确地递送瓣膜,并且还允许更牢固地将瓣膜锚固到位。
缝合孔621沿着环形区和心室区的支柱安置,以允许诸如心包或聚合物(诸如涤纶或ePTFE)等覆盖物的附接。缝合孔还可沿着框架的任何其他部分安置。倒刺623沿着心室裙部628安置,以帮助将假体瓣膜锚固到相邻的组织。连合耳片或耳片612安置在连合部613的尖端上,并且可如下文所述那样用于将连合部可释放地与递送系统相耦合。这允许框架首先扩张,并且继而可于随后从递送系统释放连合部。本领域技术人员将会理解,可以使用多种支柱几何结构,并且此外可以调整诸如长度、宽度、厚度等支柱尺寸,以便为锚固件提供期望的机械性能,诸如刚度、径向抗压强度、连合部挠曲等。因此,图示的几何结构并不旨在成为限制性的。
框架可通过EDM、激光切割、光化学蚀刻或本领域中已知的其他技术来形成。可以使用皮下注射管或平板来形成框架。一旦已切割出框架并将其形成为圆柱体,则可将其径向扩张成期望的几何形状并使用已知的工艺对其进行热处理以固化该形状。因此,可以将假体瓣膜以收缩配置装载到递送导管上并使用约束鞘套来将其约束于收缩配置。约束鞘套的移除将会允许锚固件自扩张成其无偏斜的预设形状。在其他实施方式中,可以使用诸如球囊等可扩张构件来将锚固件径向扩张成其优选的扩张配置。
图7图示了收缩配置下的假体心脏瓣膜的另一示例性实施方式,并且该假体心脏瓣膜与先前实施方式相似,主要区别在于前耳片、后耳片和心室裙部中的支柱长度。通过改变支柱长度而允许对前耳片和后耳片以及心室裙部的扩张顺序加以控制。已经从框架移除覆盖物(例如,织物或组织),以允许观察下面的框架700。该框架已被铺开和展平。假体瓣膜框架700具有心房区706、环形区708和心室区710。框架700由多个互连的支柱所形成,所述支柱形成一系列凸峰和凹谷,所述凸峰和凹谷可相对于彼此扩张和收缩从而允许将框架以收缩配置装载到递送导管上,并继而使其在靶治疗部位处径向扩张以供植入。优选实施方式为自扩张式,并且可使用超弹性镍钛诺或其他自扩张材料制成。还可以使用在高于转变温度时弹开的形状记忆合金,并且还可以使用可扩张构件以在需要塑性变形(例如,球囊扩张)来敞开框架时扩张该框架。
心房区706具有裙部716,该裙部616包括形成一系列凸峰和凹谷的多个互连的支柱。在该区域中,所述支柱相对于彼此偏斜,并且因此,所产生的单元图案具有一个扩大的末端,而相对的末端渐缩成较小的末端。心房区的前部702具有比后区704更短的支柱。因此,所述前部中的凸峰和凹谷从心房区的其余后部中的凸峰和凹谷轴向偏移。这允许创造出对准元件714来帮助医师将假体瓣膜递送到二尖瓣并在假体瓣膜的扩张之前对准假体瓣膜。心房区706的其他方面与图6中的心房区606的各方面相似。可选的不透射线标记714a安置在偏移的凸峰和凹谷的任一侧上,并且帮助在瓣膜植入期间的可视化。心房区优选地自扩张成圆柱形,或者其可具有D形横截面,其中前部702基本上是平坦的,而后部704为圆柱形。这允许心房裙部吻合天然二尖瓣的解剖结构,从而防止左心室流出道的阻塞。此外,心房裙部还可形成为使得在扩张时该裙部向外张开并形成可抵靠二尖瓣的上表面的凸缘。带凸缘的区域优选地沿着心房裙部的后部,并且心房裙部的前部保持无凸缘。或者,所述凸缘可在整个心房裙部周围延伸。心房区用连接支柱连接至相邻的环形区708,所述连接支柱优选地是直线的,并且基本上平行于框架的纵轴线。
环形区708也包含多个轴向定向并互连的支柱,所述支柱形成允许径向扩张的凸峰和凹谷。所述支柱优选地彼此平行,并且平行于框架的纵轴线。环形区也可为自扩张式,并且扩张成圆柱形,或者更优选地,环形区可扩张以具有如上文关于心房区所述的D形横截面。因此,环形区可类似地具有平坦的前部和圆柱形的后部。当递送时,环形区与二尖瓣环对准并且扩张成与二尖瓣环相接合。连接器支柱将环形区与心室区710接合起来。
心室区710也包括形成凸峰和凹谷的多个互连支柱。此外,心室区中的支柱形成小叶连合部713,所述小叶连合部713覆盖有织物、心包组织或其他材料,以形成假体瓣膜小叶。连合部中的孔允许向其附接缝合线。心室区中的支柱还形成向外扩张以接合前二尖瓣小叶和后二尖瓣小叶的心室裙部728,并且心室区中的支柱还形成前耳片724和后耳片730。前耳片被设计用于将前二尖瓣小叶捕获在前耳片的内表面与心室裙部的外表面之间。还可将任何相邻的腱索捕获在其间。另外,前耳片的尖端接合位于二尖瓣的前部上的纤维三角区,所述纤维三角区一个位于左侧,一个位于右侧。后耳片类似地将后二尖瓣小叶连同任何相邻的腱索一起捕获在后耳片的内表面与心室裙部的外表面之间。这将在下文中更详细地描述。
通过沿着框架控制前耳片或后耳片的支柱长度或轴向位置,可以控制耳片的展开。因此,在本示例性实施方式中,由于前耳片724和后耳片730中的支柱的长度及其沿着框架的相对位置彼此相同,因此当从耳片缩回约束鞘套时,前耳片和后耳片将会部分地一起向外弹出。随着约束鞘套被进一步缩回,前耳片的其余部分将会径向向外自扩张,这是因为它们相对于心室裙部和后耳片中的支柱是最短的。约束鞘套的进一步回缩继而允许心室裙部径向扩张,并且最终鞘套的进一步回缩允许后耳片的其余部分完成其径向扩张。使用这样的假体瓣膜展开顺序可以允许更准确地递送瓣膜,并且还允许更牢固地将瓣膜锚固到位。
缝合孔721沿着环形区和心室区的支柱安置,以允许诸如心包或聚合物(诸如涤纶或ePTFE)等覆盖物的附接。缝合孔还可沿着框架的任何其他部分安置。倒刺723沿着心室裙部728安置,以帮助将假体瓣膜锚固到相邻的组织。连合耳片或耳片712安置在连合部713的尖端上,并且可如下文所述那样用于将连合部可释放地与递送系统相耦合。这允许框架首先扩张,并且继而可于随后从递送系统释放连合部。本领域技术人员将会理解,可以使用多种支柱几何结构,并且此外可以调整诸如长度、宽度、厚度等支柱尺寸,以便为锚固件提供期望的机械性能,诸如刚度、径向抗压强度、连合部挠曲等。因此,图示的几何结构并不旨在成为限制性的。可以类似于上文关于图6所描述那样形成框架。
图8图示了收缩配置下的假体心脏瓣膜的另一示例性实施方式,并且该假体心脏瓣膜与先前实施方式相似,主要区别在于后耳片被设计用于扩张以形成细长的水平区段,所述细长水平区段允许后耳片与位于后小叶和心室壁之间的环下区域的接合和锚固。因此,所述细长水平区段与仅具有由支柱间的单一合页所形成的渐缩尖端的后耳片相比接触环下区域的更大区域。这提供了假体瓣膜的增强的锚固。在该示例性实施方式中,前耳片将会首选完全自扩张,随后是后耳片,继而是心室裙部。然而,在一些情况下,诸如递送系统、解剖结构等外部因素可改变扩张的顺序,因此这样的顺序并不旨在成为限制性的。已经从框架移除覆盖物(例如,织物或组织),以允许观察下面的框架800。该框架已被铺开和展平。假体瓣膜框架800具有心房区806、环形区808和心室区810。框架800由多个互连的支柱所形成,所述支柱形成一系列凸峰和凹谷,所述凸峰和凹谷可相对于彼此扩张和收缩从而允许将框架以收缩配置装载到递送导管上,并继而使其在靶治疗部位处径向扩张以供植入。优选实施方式为自扩张式,并且可使用超弹性镍钛诺或其他自扩张材料制成。还可以使用在高于转变温度时弹开的形状记忆合金,并且还可以使用可扩张构件以在需要塑性变形(例如,球囊扩张)来敞开框架时扩张该框架。
心房区806具有裙部816,该裙部816包括形成一系列凸峰和凹谷的多个互连的支柱。在该区域中,所述支柱相对于彼此偏斜,并且因此,所产生的单元图案具有一个扩大的末端,而相对的末端渐缩成较小的末端。心房区的前部802具有比后区804更短的支柱。因此,所述前部中的凸峰和凹谷从心房区的其余后部中的凸峰和凹谷轴向偏移。这允许创造出对准元件814来帮助医师将假体瓣膜递送到二尖瓣并在假体瓣膜的扩张之前对准假体瓣膜。心房区806的其他方面与图6中的心房区606的各方面相似。可选的不透射线标记814a安置在偏移的凸峰和凹谷的任一侧上,并且帮助在瓣膜植入期间的可视化。心房区优选地自扩张成圆柱形,或者其可具有D形横截面,其中前部802基本上是平坦的,而后部804为圆柱形。这允许心房裙部吻合天然二尖瓣的解剖结构,从而防止左心室流出道的阻塞。此外,心房裙部还可形成为使得在扩张时该裙部向外张开并形成可抵靠二尖瓣的上表面的凸缘。带凸缘的区域优选地沿着心房裙部的后部,并且心房裙部的前部保持无凸缘。或者,所述凸缘可在整个心房裙部周围延伸。心房区用连接支柱连接至相邻的环形区808,所述连接支柱优选地是直线的,并且基本上平行于框架的纵轴线。
环形区808也包含多个轴向定向并互连的支柱,所述支柱形成允许径向扩张的凸峰和凹谷。所述支柱优选地彼此平行,并且平行于框架的纵轴线。环形区也可为自扩张式,并且扩张成圆柱形,或者更优选地,环形区可扩张以具有如上文关于心房区所述的D形横截面。因此,环形区可类似地具有平坦的前部和圆柱形的后部。当递送时,环形区与二尖瓣环对准并且扩张成与二尖瓣环相接合。连接器支柱将环形区与心室区810接合起来。
心室区810也包括形成凸峰和凹谷的多个互连支柱。此外,心室区中的支柱形成小叶连合部813,所述小叶连合部813覆盖有织物、心包组织或其他材料,以形成假体瓣膜小叶。连合部中的孔允许向其附接缝合线。心室区中的支柱还形成向外扩张以接合前二尖瓣小叶和后二尖瓣小叶的心室裙部828,并且心室区中的支柱还形成前耳片824和后耳片830。前耳片被设计用于将前二尖瓣小叶捕获在前耳片的内表面与心室裙部的外表面之间。还可将任何相邻的腱索捕获在其间。另外,前耳片的尖端接合位于二尖瓣的前部上的纤维三角区,所述纤维三角区一个位于左侧,一个位于右侧。后耳片类似地将后二尖瓣小叶连同任何相邻的腱索一起捕获在后耳片的内表面与心室裙部的外表面之间。这将在下文中更详细地描述。后耳片与上文所述图6-图7中的后耳片相似,不同之处在于在本实施方式中,后耳片包括四个互连支柱而不是两个互连支柱。因此,在本实施方式中,所述多个互连支柱沿着耳片形成三个铰接区836。当后耳片扩张时,所述铰接区也将会扩张,从而形成细长的水平区段,所述细长水平区段允许后耳片与位于后小叶和心室壁之间的环下区域的接合和锚固。这样可以比仅具有较小的占位面积或单一的渐缩尖端的后耳片更好地帮助定位和锚固假体瓣膜以供接合二尖瓣的后部。本实施方式中的后小叶可由本说明书中描述的任何其他后耳片所替代。
通过沿着框架控制前耳片或后耳片的支柱长度或轴向位置,可以控制耳片的展开。因此,在本示例性实施方式中,由于前耳片824和后耳片830中的支柱的长度及其沿着框架的相对位置彼此相同,因此当从耳片缩回约束鞘套时,前耳片和后耳片将会部分地一起向外弹出。随着约束鞘套被进一步缩回,前耳片的其余部分将会径向向外自扩张,这是因为它们相对于心室裙部和后耳片中的支柱是最短的。约束鞘套的进一步回缩继而允许后耳片的其余部分完成自扩张,随后是心室裙部的自扩张。使用这样的假体瓣膜展开顺序可以允许更准确地递送瓣膜,并且还允许更牢固地将瓣膜锚固到位。
缝合孔821沿着环形区和心室区的支柱安置,以允许诸如心包或聚合物(诸如涤纶或ePTFE)等覆盖物的附接。缝合孔还可沿着框架的任何其他部分安置。倒刺823沿着心室裙部828安置,以帮助将假体瓣膜锚固到相邻的组织。连合耳片或耳片812安置在连合部813的尖端上,并且可如下文所述那样用于将连合部可释放地与递送系统相耦合。这允许框架首先扩张,并且继而可于随后从递送系统释放连合部。本领域技术人员将会理解,可以使用多种支柱几何结构,并且此外可以调整诸如长度、宽度、厚度等支柱尺寸,以便为锚固件提供期望的机械性能,诸如刚度、径向抗压强度、连合部挠曲等。因此,图示的几何结构并不旨在成为限制性的。可以类似于上文关于先前在上文描述的框架所描述的那样形成框架。
图9A图示了在已扩张之后的假体心脏瓣膜的框架900。由于每个上述框架都具有类似的几何结构,因此任何上述框架实施方式均可采取这种形式,但它们以不同的顺序扩张。框架包括具有前部914和后部916的心房裙部906。所述后部周围形成带凸缘的区域,而所述前部保持无凸缘。此外,前部大体上是平坦的,而后部为圆柱形,从而形成适应二尖瓣解剖结构的D形横截面。图9B为图9A中的实施方式的俯视图,并且更清楚地图示了所述D形横截面。
框架还包括环形区910和心室裙部912。前耳片904(在该视图中仅有一个可见)完全扩张,使得在前耳片的内表面与心室裙部的外表面之间存在空间。这允许将前小叶和相邻的腱索捕获于其间。类似地,后耳片902也完全展开,且在后耳片902的内表面与心室裙部的外表面之间具有类似的空间。这允许将后小叶和相邻的腱索捕获于其间。还可看到连合杆908,并且其安置在由框架所形成的内通道中。连合杆用于形成假体二尖瓣小叶。扩张的框架的整体形状为D形,其中前部是平坦的而后部为圆柱形。
图10图示了扩张的框架由附接至框架的诸如心包组织或者如ePTFE等聚合物或者如涤纶等织物之类的覆盖物1002所覆盖,从而形成假体心脏瓣膜1000。心房裙部可完全由材料所覆盖,或者在优选实施方式中,仅将覆盖物安置在心房裙部的带凸缘的部分中的相邻单元中的相邻支柱1012之间。位于相同单元内的相邻支柱之间的区域1014保持无覆盖。这允许在植入假体瓣膜的同时保持血液流动基本上不受妨碍。可以使用缝合线1010来将覆盖物附接至框架。在该视图中,只有假体瓣膜的后部上的后耳片1006连同心室裙部1008和心房裙部1004是可见的。
小叶锚固。
使用心房裙部、环形区和心室裙部将假体瓣膜锚固到天然二尖瓣。前耳片和后耳片通过接合前小叶和后小叶而进一步将假体瓣膜锚固到二尖瓣。由于瓣膜小叶在移动,因此接合小叶可能具有挑战性。除了本文所公开的锚固结构及其展开顺序之外,还可以控制假体瓣膜展开的其他方面,以便在装置的展开过程中成功捕获并容纳心脏的相关解剖结构。其中一些方面包括谨慎细致地设计通过激光切割过程实现的假体瓣膜框架的特定几何形状、通过框架形状固化实现的框架的特定几何形状,以及框架的特定部分与递送系统的相互作用,所述递送系统具有设计用于与框架以可控方式相互作用的专用组件。
图14图示了在具有前小叶AL和后小叶PL的二尖瓣MV中部分地展开的假体瓣膜1408。该图的放大部分突出图示了处于部分展开状态下的耳片,并继而还图示了处于完全展开状态下的耳片。图示的耳片可为假体瓣膜上的前耳片或后耳片。递送系统1402已在导丝GW上经心尖递送,以跨越左心室LV和右心房RA。随着递送系统外鞘套1404被缩回,心房裙部1410如前文所述随同环形区1412和心室裙部1414一起展开。外鞘套1404约束前耳片和后耳片1406的基部部分,从而只允许耳片在心房裙部之后部分地径向向外扩张至横向于假体的纵轴线的水平位置或基本上水平的位置。这在心房裙部1410的边缘与耳片1406的尖端之间形成了窗口1416,该窗口1416可接纳瓣膜小叶。优选地,该窗口间隙尽可能宽,以便确保瓣膜小叶进入窗口。一旦外鞘套1404完全缩回,则心室裙部1414随同耳片1406一起完全展开。从外鞘套的约束中释放耳片的基部部分,这允许耳片进一步从其水平位置或基本上水平的位置径向向外扩张至更加垂直的位置。所述更加垂直的位置可平行于或基本上平行于假体的纵轴线,并且可仍然横向于假体的纵轴线,但其间的角度相对于耳片的基部部分被释放时有所减小。因此,耳片1406的尖端也向心房裙部1410的边缘移近,从而关闭窗口1416并帮助确保瓣膜小叶将会被接合于其中。因此,期望在展开过程中控制窗口的尺寸,以确保在展开过程中的最大间隙,以及在完全展开之后的最小间隙。
图15A-图15B图示了假体瓣膜从递送系统的释放,并且还图示了小叶接纳窗口的配置在展开的各个阶段期间如何改变。在图15A中,递送系统1402的外鞘套1404已被部分地缩回远离假体瓣膜,使得心房裙部1410和环形区1412已经自扩张。类似地,心室裙部1414已随同心室耳片1406一起部分地自扩张。心室耳片1406可以是前耳片或后耳片。心室耳片1406的尖端1406a不受约束,并径向向外自扩张至横向于假体的纵轴线的几乎水平的位置或基本上水平的位置,而心室耳片1406的基部1406b保持被约束在外鞘套1404的尖端1404a之下。连合杆1420将假体瓣膜与递送导管相耦合,这是因为连合杆1420的一端保持在递送导管上的容器1422中,并且这由安置在内导管1424上的钟形导管1418所约束。因此,在图15A中,窗口1416形成于耳片1406的尖端1406a与心房裙部1410的边缘1410a之间。尖端1406a与边缘1410之间的间隙在此位置上最大,以便允许接纳瓣膜小叶。继而将瓣膜小叶接纳在小叶容器中,该小叶容器由心房裙部1410的内表面、环形区1412的外表面、心室裙部1414的外表面以及心室耳片1406的内表面所形成。
在图15B中,外鞘套1404已进一步缩回,因此从外鞘套1404的约束中释放心室耳片1406的基部1406b,从而允许心室裙部1414和心室耳片1406进一步径向向外自扩张。因此基部1406b向外自扩张并枢转或摆动远离递送系统。这导致心室耳片1406的尖端1406a旋转和平移,以使其向上移动并更加靠近心房裙部1410的边缘1410a,从而减小间隙并至少部分地关闭窗口1416。耳片还从其水平位置或基本上水平的位置径向向外扩张至更加垂直的位置,该位置可平行于或基本上平行于假体的纵轴线,并且可以仍然横向于假体的纵轴线。耳片与心室裙部之间的夹角因此相对于当耳片的基部部分被释放时减小,并且窗口优选地充分关闭,以使瓣膜小叶接合于小叶容器中,从而将假体瓣膜锚固到小叶。如本说明书中其他部分所述,连合杆1420保持耦合至递送系统,直到稍后缩回钟形导管。虽然本说明书只描述了一个心室耳片,但本领域技术人员将会理解,相同的公开内容可适用于假体瓣膜中的所有心室耳片,例如,在本文的实施方式中所述的两个前耳片和一个后耳片。
图16A-图16B与图15A相似,但提供了与假体瓣膜的展开有关的定点标记信息。为便于讨论,已经重新标记了特征。这些标志物用于帮助描述在假体瓣膜的展开过程中发生的机械相互作用。虽然不受任何特定理论的限制,以下操作变量和机制被认为是与假体瓣膜的相互作用和展开相关,并且它们被标记如下:
A=递送系统的容器中瓣膜连合部的锚固点
B=连合杆向心室裙部中的插入点
C=心房裙部的边缘
D=心室耳片的尖端
E=心室裙部支柱向心室耳片中的插入点
F=外鞘套导管的前缘
G=心室耳片的基部与钟形导管的接触点
Z=点C与点D之间的法向距离
β=线AB与线BE之间的夹角
α=线BE与线ED之间的夹角
图17A-图20B示意性地图示了假体瓣膜和递送系统以及各种替代实施方式,目的在于探究假体瓣膜的各个方面与递送系统的相应特征之间的相互作用。这些示图旨在提供支架的所有相关结构的简单示意图,并进一步详述所存在的固有的固体机械变形。示图在视觉上简化导致假体瓣膜的释放和展开的机制,并且还提供用于描述通过对假体瓣膜和/或递送系统的几何和机械操纵而控制展开的替代实施方式的架构。
图17A图示了从递送系统部分地展开的假体瓣膜。因此,在图17A中,如先前在上文中所述,由ED限定的心室耳片水平地或基本上水平地延伸。图17B图示了在进一步展开之后但尚未完全从递送系统释放的假体瓣膜。如先前在上文中所述,心室耳片改变位置以使其现在垂直定向并平行或基本上平行于假体的纵轴线。令点C和点D位于水平的平行平面内。令点C与点D之间的法向距离称为Z1。为了在假体瓣膜的展开过程中成功接纳并接合天然二尖瓣小叶,优选地使Z1最大化。这样做的原因很简单。由点C、点B、点E和点D所界定的区域可被认为是在其中发生小叶接纳和接合的窗口、容器或空间,并且将会成为在展开之后天然小叶所位于的空间(由图17B中的C、B、E、D所界定的区域)。因此,窗口(Z1)越大,在展开过程中捕捉小叶的几率就越大。如图17B中所示,最终杆展开配置展现了Z2显著小于Z1,图示了心室耳片(前耳片,或后耳片,或其他耳片)对于天然二尖瓣小叶所具有的接扣或“抓握”作用。由于优选的实施方式将会允许Z1最大化,因此在下文中描述可用于获得最大窗口尺寸的技术和方法。
如图17A中并关于假体瓣膜的形状设定所示,至少可以操纵三个主要属性以将Z1最大化。假设不对包括由B所指定的点上方的任何几何结构在内的假体瓣膜的心房侧作出改变。
对于第一属性,可对分支ED进行修改。通过逐渐向下并远离EB弯曲ED,点D被显著降低,并且距离Z1变得更大。还可通过对分支ED进行形状设定以使之处于与EB的更大夹角来增大角α1,在点E处开始弯曲并允许ED绕点E旋转。
第二属性是分支BE的长度。所有其他分支保持不变,如果使分支BE更长,则趋势是使分支FED下垂,从而使其绕点F旋转并增大α1。
第三属性是分支EG的形状,及其与点F的相互作用。随着心室耳片被释放,沿着点F拖动基部(分支EG),点F代表外鞘套导管的前缘。通过向下并远离分支EB弯曲分支EG,心室耳片既延迟释放(非常有用的特性),又以更大的角度α1展开。在保持分支GD的长度的同时减小分支EG的长度还具有杠杆作用,这样放大了分支EB与ED之间的角位移。在示意图中,这通过移动心室耳片的附接点(E)使其更靠近点F来实现。因此,EG关于E的任何角位移都将被放大,并且分支ED的角位移(α1)将会增大。在实践中,还可通过对递送系统的特定部分的几何形状进行精细操纵来产生这样的作用,而这些操纵在下文中更详细地描述。
图18A-图20B示意性地图示了假体瓣膜和具有帮助使窗口尺寸Z1最大化的特征的递送系统的各个实施方式。再次假设不对包括由B所指定的点上方的任何几何结构在内的假体瓣膜的心房侧作出改变。在这些情况下,所有用于影响Z1的方法都通过假体瓣膜与递送系统之间的相互作用来实现,而不是通过对假体瓣膜几何形状或形状设定过程的操纵而实现。心房裙部或凸缘首先展开并将假体锚固于心房中,并且继而将假体的其余部分锚固到二尖瓣环和心室。心室耳片与上文所述类似地展开;当首先部分地展开时,其为水平的或基本上水平的,并且在从递送系统释放耳片之后,耳片更加垂直地移动以使其平行或基本上平行于假体的纵轴线。
图18A图示了利用见于分支EG与分支ED之间的杠杆作用的第一实施方式。通过减小图18B中所示的点G与点F之间的水平距离,再次增大角位移(α1)。然而,在这种情况下通过外鞘套导管1404的直径的减小来实现改变,这使得其更靠近钟形导管1418,并从而发挥作用以缩短分支FG。在这种情况下,不同于当采用假体瓣膜修改时的点E,在点F处更易于感觉到支点。图18B示意性地图示了该实施方式以及由此产生的更大的窗口Z1。
图19A-图19B图示了用于增大窗口尺寸Z1的第二实施方式。第二属性利用可在鞘套导管1404的前缘上采用的凸轮作用。在图19A中,图示了凸轮形内表面1902。该凸轮形内表面1902可为环形内凸缘或其他与假体瓣膜上的分支FG的规定形状相互作用的结构,并且充当由分支ED所体现的、用于精确控制直动从动件的用途的直动凸轮。在这方面,可以通过使用凸轮作用来同时控制角位移率和角位移(α1)。因此,可以更精确地控制在展开过程中观察到的心室耳片的回弹速度,尽管其仍在很大程度上依赖于制作心室耳片所使用的材料的弹簧刚度。图19B图示了在展开过程中凸轮1902与心室耳片的基部的接合,这由于凸轮导致心室耳片的尖端在展开过程中采取更加水平的位置而促进了更宽的窗口Z1的形成。
图20A-图20B图示了用于增大窗口尺寸Z1的另一实施方式。第三属性采取推动机构的形式,诸如与点G和点F之间的心室耳片的基部的部分相互作用的推动器元件2012。通过在G的位置上对假体瓣膜直接向上施力,能够以可控的方式直接影响ED绕点E的旋转。图20B图示了推动器元件2012推抵心室耳片的基部,从而进一步打开窗口Z1。
递送系统。图11A-图11D图示了可用于递送本说明书中所公开的任何假体心脏瓣膜的递送系统的示例性实施方式。递送系统的制动允许假体心脏瓣膜如本说明书中其他部分所述那样展开。虽然该递送系统设计用于优选地经心尖递送假体心脏瓣膜,但本领域技术人员将会理解,还可对其做出修改以便可以诸如使用经中隔路径,腔内地经由导管递送假体瓣膜。本领域技术人员将会理解,使用经中隔路径可能要求修改各个轴的相对运动以便适应递送系统相对于二尖瓣的位置。
图11A图示了递送系统1100的透视图。递送系统1100包括靠近递送系统的近端的手柄1112和远侧组织穿透尖端1110。递送系统中包括4个细长轴,这些细长轴包括:外鞘套导管轴1102;钟形导管轴1104,其可滑动地安置在外鞘套导管轴1102中;衬套导管轴1106,其相对于其他的轴保持静止,但所述钟形导管轴相对于该衬套轴滑动;以及最后的内导丝导管轴1108,其也相对于其他的轴固定,并且具有管腔,该管腔的尺寸设定用于接纳从中穿过并穿出远侧组织穿透尖端的导丝。如下文将会更详细地解释,使用致动器机构1114来控制各轴的移动,并且使用具有鲁尔连接器(luer connector)的冲洗线1116、1118来冲洗相邻的轴之间的环形区域。冲洗线1118用于冲洗外鞘套导管轴1102与钟形导管轴1104之间的环形空间。冲洗线1116用于冲洗钟形导管1104与衬套导管1106之间的环形空间。内导丝导管轴1108相对于衬套导管1106静止,因此可以用O形环或其他材料来密封环形空间。鲁尔连接器1122允许对导丝管腔的冲洗,并且可以将诸如Tuohy-Borst之类的止血阀耦合至鲁尔连接器以允许在保持止血的同时推进导丝穿过导丝导管轴。螺杆1120保持手柄壳体耦合在一起。图11B图示了递送系统1100的侧视图。
图11C为递送系统1100的局部分解图,并且更清楚地图示了手柄1112中的组件以及它们如何相互作用。手柄1112包括具有两个半部1112a、1112b的壳体,所述两个半部1112a、1112b容纳所有的组件。手柄优选地由螺杆1120和螺母1120b保持在一起,但其还可使用诸如压配合、卡扣配合、粘接、超声焊接等其他技术来密封。致动器轮1114的旋转转化为螺纹嵌件1124的直线运动。外鞘套导管轴1102耦合至螺纹嵌件1124,因此致动器轮1114在一个方向上的旋转将会推进鞘套导管轴1102,而在相反方向上的旋转将会缩回鞘套导管轴1102。致动器轮1114的进一步旋转将螺纹嵌件1124缩回到足以碰到耦合至嵌件1128的销钉1126,从而还移动嵌件1128。钟形导管轴1106耦合至嵌件1128,因此致动器轮1114的进一步旋转将会移动外轴1102并且还移动钟形导管轴1106。致动器轮在相反方向上的旋转推进鞘套,并且螺纹嵌件1124从销钉1126脱离。弹簧1130使嵌件1128回到其无偏斜位置,从而使钟形导管轴回到其无偏斜位置。
本文所公开的任何假体心脏瓣膜均可由递送系统1100来携带。心房裙部、环形裙部、前耳片、后耳片和心室裙部被装载在钟形导管轴上,并且安置在外鞘套导管轴1102之下。心室裙部被装载在近端使得其最靠近手柄1112,并且心房裙部被装载在最远端因此其最靠近尖端1110。因此,外鞘套导管轴1102的回缩在控制假体心脏瓣膜的展开中发挥重要作用。心房裙部因此在外鞘套导管缩回时首先扩张。假体瓣膜连合部可与衬套导管1106的远侧部分上的衬套1106a相耦合,并且继而将钟形导管轴安置在其上,从而将连合部可释放地与递送导管相接合。一旦假体心脏瓣膜的其他部分已经扩张,即可释放连合部。
图11D突出图示了递送系统1100的远侧部分。外鞘套导管轴1102相对于可滑动地安置在外鞘套导管轴1102中的钟形导管轴1104推进和缩回。图中示出衬套导管轴1106可滑动地安置在钟形导管轴1104中并且钟形导管轴1104被缩回,以便暴露出具有容纳假体瓣膜连合部的槽1106b的衬套1106a。内导丝导管轴1108为最内层的轴,并且具有渐缩的锥形区段1130,该锥形区段1130为假体瓣膜提供平滑过渡并且防止假体心脏瓣膜框架的不期望的弯曲或屈曲。组织穿透尖端1110适于穿透组织,特别是在经心尖心脏手术中穿透组织。
递送方法。可以使用多种方法来将假体心脏瓣膜递送到心脏。递送假体二尖瓣的示例性方法可包括腔内递送路径,这还可以是一种穿过心脏的右侧与左侧之间的隔膜的经中隔技术,或者在更优选的实施方式中,可以使用诸如图12A-图12L中所图示的经心尖路径。可以使用先前在上文中所述的递送装置来递送本文所述的假体瓣膜的任何实施方式,或者还可使用其他递送装置和其他假体瓣膜,诸如在先前通过引用并入本文的美国专利申请No.13/096,572中所公开的递送装置和假体瓣膜。然而,在这个优选的示例性实施方式中,使用图6的假体心脏瓣膜,使得前耳片首先展开,随后展开后耳片,并继而展开心室裙部。
图12A图示了包括左心房LA和左心室LV在内的患者心脏左侧的基本解剖结构。肺静脉PV将血液从肺部返回到左心房,而血液继而从左心房跨二尖瓣MV被泵送到左心室中。二尖瓣包括位于瓣膜的前侧A上的前小叶AL和位于瓣膜的后侧P上的后小叶PL。所述小叶附接至腱索CT,所述腱索CT接着由乳头肌PM紧固到心脏壁。血液继而被泵出左心室而进入主动脉Ao,并有主动脉瓣AV阻止反流。
图12B图示了递送系统1202穿过心脏的顶点向左心房LA中的经心尖递送。递送系统1202可在导丝GW上推进到左心房中,并且组织穿透尖端1204通过扩张组织并形成用于让递送系统的其余部分穿过的较大的通道来帮助递送系统穿过心脏的顶点。递送导管携带假体心脏瓣膜1208。一旦已将递送系统的远侧部分推进到左心房中,即可向近侧(例如,朝向操作者)缩回外鞘套1206,从而从假体瓣膜1208的心房部分移除约束。这允许心房裙部1210首先径向向外自扩张。在图12C中,随着外鞘套被进一步缩回,心房裙部继续自扩张并向外探出,直到其如图12D中所示完全展开。心房裙部可具有圆柱形的形状,或者其可如上文所讨论那样为D形并具有平坦的前部和圆柱形的后部以便避免妨碍主动脉瓣和左心室流出道的其他方面。可以向上游或下游推进假体心脏瓣膜,以正确定位心房裙部。在优选实施方式中,心房裙部形成抵靠二尖瓣的上表面的凸缘,而这对假体瓣膜加以锚固并阻止其不期望地向下游移动到左心室中。首先将假体锚固于心房中是意料之外的,这是因为将假体锚固到移动的瓣膜小叶是具有挑战性的,并且通常将会首先进行,随后是可能更容易的心房锚固。然而,首先进行心房锚固可以帮助更牢固地放置假体。当然,本领域技术人员认识到,假体可以基于所使用的递送系统以及假体自身的设计而以任何期望的顺序展开。因此,当前的假体瓣膜可不同于先前的假体瓣膜而锚固自身。先前的假体瓣膜可被动锚固,这是因为它们可通过从递送系统抽出并继而被推动到小叶之后就位继而进行心房锚固而得到递送。由于这个原因,需要首先展开小叶锚固件,随后展开心房锚固件,所述心房锚固件由于相对较平的心房层面而更易于展开。在本实施方式中采用主动锚固,这是因为锚固件在展开顺序过程中改变位置和定向以捕获心室结构,并从而允许使用与先前的假体瓣膜相反的锚固顺序。
随着外鞘套1206继续向近侧缩回,接下来假体心脏瓣膜的环形区自扩张成与瓣膜环相接合。环形区也优选地具有D形几何形状,但其还可为圆柱形或者具有其他几何形状以匹配于天然解剖结构。在图12E中,鞘套1206的回缩最终允许前耳片1212和后耳片1214同时部分地向外自扩张而优选地不接合前小叶或后小叶或者腱索。耳片最初向外扩张至横向于假体的纵轴线的水平或基本上水平的位置。在该实施方式中,外鞘套1206的进一步回缩继而允许全部两个前耳片1212(在该视图中仅有一个可见)完成它们的自扩张,以便如图12F中所示将前小叶捕获在每个前耳片的内表面与心室裙部1216的外表面之间。前耳片扩张至平行于或基本上平行于假体的纵轴线的更加垂直的位置。耳片可仍然横向于假体的纵轴线。后耳片1214保持部分敞开,但尚未完成其扩张。此外,如将在下文中更详细地说明,前耳片的尖端还锚固到二尖瓣的左纤维三角区和右纤维三角区中。
在图12G中,外鞘套1206的进一步回缩继而从后耳片1214释放约束,从而允许其完成其自扩张,由此将后小叶PL捕获在后耳片1214的内表面与心室裙部1218的外表面之间。因此,后小叶从水平位置或基本上水平的位置移动至平行于或基本上平行于假体的纵轴线的更加垂直的位置。在图12H中,鞘套被进一步缩回,从而释放心室裙部1220并允许心室裙部1220径向向外扩张,进一步将前小叶和后小叶捕获在心室裙部的外表面与它们相应的前耳片或后耳片之间。心室裙部的扩张还向外推动前小叶和后小叶,从而确保天然小叶不妨碍假体瓣膜或假体瓣膜小叶的任何部分。现在,假体瓣膜在二尖瓣之上、沿着环部、向瓣膜小叶以及在二尖瓣之下被锚固到位,从而将其紧固就位。
现在,如图12I中所示,递送装置的进一步致动将外鞘套1206和钟形导管轴1222缩回,以便从衬套导管1224移除约束。这允许从衬套导管释放假体瓣膜连合部1226,因此连合部扩张成它们的偏斜配置。继而如图12J中所示,移除递送系统1202和导丝GW,将假体瓣膜1208留在其替代天然二尖瓣的位置上。
图12K和图12L突出图示了前耳片和后耳片与相应的前小叶和后小叶的接合。在图12K中,在前耳片1212已经完全扩张之后,它们将前小叶AL和相邻的腱索捕获在前耳片的内表面与心室裙部1220的外表面之间。此外,前耳片1212的尖端1228与二尖瓣的前侧的纤维三角区FT相接合。所述纤维三角区为瓣膜的纤维区,因此前耳片进一步将假体瓣膜锚固到天然二尖瓣解剖结构中。一个前耳片锚固到左纤维三角区中,而其他前耳片锚固到右纤维三角区中。所述三角区位于小叶的前侧的相对两侧上。图12L图示了后耳片1214与后小叶PL的接合,所述后小叶PL被捕获在后耳片的内表面与心室裙部1220的外表面之间。此外,相邻的腱索也被捕获在后耳片与心室裙部之间。
图13A-图13L图示了递送方法的另一示例性实施方式。该实施方式类似于先前所述的实施方式,主要区别在于假体心脏瓣膜自扩张成与二尖瓣相接合的顺序。本文所公开的任何递送装置或任何假体心脏瓣膜均可使用,然而在优选实施方式中,使用图7的实施方式。改变所述顺序可允许更好地定位植入物、更容易地捕获瓣膜小叶,以及更好地锚固植入物。该示例性方法还优选地使用经心尖路径,但还可使用经中隔路径。
图13A图示了包括左心房LA和左心室LV在内的患者心脏左侧的基本解剖结构。肺静脉PV将血液从肺部返回到左心房,而血液继而从左心房跨二尖瓣MV被泵送到左心室中。二尖瓣包括位于瓣膜的前侧A上的前小叶AL和位于瓣膜的后侧P上的后小叶PL。所述小叶附接至腱索CT,所述腱索CT接着由乳头肌PM紧固到心脏壁。血液继而被泵出左心室而进入主动脉AO,并有主动脉瓣AV阻止血液从主动脉反流回左心室中。
图13B图示了递送系统1302穿过心脏的顶点向左心房LA中的经心尖递送。递送系统1302可在导丝GW上推进到左心房中,并且组织穿透尖端1304通过扩张组织并形成用于让递送系统的其余部分穿过的较大的通道来帮助递送系统穿过心脏的顶点。递送导管携带假体心脏瓣膜1308。一旦已将递送系统的远侧部分推进到左心房中,即可向近侧(例如,朝向操作者)缩回外鞘套1306,从而从假体瓣膜1308的心房部分移除约束。这允许心房裙部1310径向向外自扩张。在图13C中,随着外鞘套被进一步缩回,心房裙部继续自扩张并向外探出,直到其如图13D中所示完全展开。心房裙部可具有圆柱形的形状,或者其可如上文所讨论那样为D形并具有平坦的前部和圆柱形的后部以便避免妨碍主动脉瓣和左心室流出道的其他方面。可以向上游或下游推进假体心脏瓣膜,以正确定位心房裙部。在优选实施方式中,心房裙部形成抵靠二尖瓣的上表面的凸缘,而这对假体瓣膜加以锚固并阻止其不期望地向下游移动到左心室中。因此,如前文所述,首先将假体锚固到心房是意料之外的,并且促进了假体的锚固。
随着外鞘套1306继续向近侧缩回,接下来假体心脏瓣膜的环形区自扩张成与瓣膜环相接合。环形区也优选地具有D形几何形状,但其还可为圆柱形或者具有其他几何形状以匹配于天然解剖结构。在图13E中,鞘套1306的回缩最终允许前耳片1312和后耳片1314同时部分地向外自扩张而优选地不接合前小叶或后小叶或者腱索。耳片具有与前文在先前的实施方式中所述相似的水平或基本上水平的位置。在该实施方式中,外鞘套1306的进一步回缩继而允许全部两个前耳片1312(在该视图中仅有一个可见)完成它们的自扩张,以便如图13F中所示将前小叶捕获在每个前耳片的内表面与心室裙部1316的外表面之间。因此,耳片将会具有如先前所述的平行于或基本上平行于假体的更加垂直的位置。后耳片1214保持部分敞开,并且具有大体上与前文所述相同的位置,但尚未完成其扩张。此外,如将在下文中更详细地说明,前耳片的尖端还锚固到二尖瓣的左纤维三角区和右纤维三角区中。
在图13G中,外鞘套1306的进一步回缩继而从心室裙部1320释放约束,从而允许心室裙部径向扩张。这继而进一步将前小叶AL捕获在前耳片1312与心室裙部1316之间。心室裙部的扩张还向外推动前小叶和后小叶,从而确保天然小叶不妨碍假体瓣膜或假体瓣膜小叶的任何部分。如图13H中所示的鞘套1306的进一步回缩从后耳片1314释放约束,从而允许其完成其自扩张,由此将后小叶PL捕获在后耳片1314的内表面与心室裙部1318的外表面之间。后耳片继而采取类似于先前在上文中所述的更加垂直的位置。现在,假体瓣膜在二尖瓣之上、沿着环部、向瓣膜小叶以及在二尖瓣之下被锚固到位,从而将其紧固就位。
现在,如图13I中所示,递送装置的进一步致动将外鞘套1306和钟形导管轴1322缩回,以便从衬套导管1324移除约束。这允许从衬套导管释放假体瓣膜连合部1326,因此连合部扩张成它们的偏斜配置。继而如图13J中所示,移除递送系统1302和导丝GW,将假体瓣膜1308留在其替代天然二尖瓣的位置上。
图13K和图13L突出图示了前耳片和后耳片与相应的前小叶和后小叶的接合。在图13K中,在前耳片1312已经完全扩张之后,它们将前小叶AL和相邻的腱索捕获在前耳片的内表面与心室裙部1320的外表面之间。此外,前耳片1312的尖端1328与二尖瓣的前侧的纤维三角区FT相接合。所述纤维三角区为瓣膜的纤维区,因此前耳片进一步将假体瓣膜锚固到天然二尖瓣解剖结构中。一个前耳片锚固到左纤维三角区中,而另一前耳片锚固到右纤维三角区中。所述三角区位于小叶的前侧的相对两侧上。图13L图示了后耳片1314与后小叶PL的接合,所述后小叶PL被捕获在后耳片的内表面与心室裙部1320的外表面之间。此外,相邻的腱索也被捕获在后耳片与心室裙部之间。
虽然本文已经示出和描述了本发明的优选实施方式,但对于本领域技术人员而言将会显而易见的是,此类实施方式只是以举例的方式提供的。本领域技术人员将会想到众多不偏离本发明的变化、改变和替换。应当理解,在实践本发明的过程中可以采用对本文所述发明的实施方式的各种替代方案。以下权利要求旨在限定本发明的范围,并因此涵盖这些权利要求范围内的方法和结构及其等效方案。
Claims (15)
1.一种假体瓣膜,包括:
自扩张框架,其具有上端、下端和其间的中段,其中该框架具有扩张配置和收缩配置,所述收缩配置适于递送到患者的心脏,而所述扩张配置适于将所述自扩张框架锚固在患者的心脏中,其中所述框架包括:
自扩张心房裙部,其与所述上端相邻,其中所述心房裙部在其自扩张之后形成带凸缘的区域,该带凸缘的区域配置用于将所述自扩张框架锚固到心脏的心房表面,并且其中所述带凸缘的区域包括凸缘的边缘;
自扩张心室裙部,其与所述下端相邻,其中所述心室裙部在其自扩张之后将所述自扩张框架锚固到心脏的心室表面;以及
第一自扩张耳片,其与所述下端相邻并与所述心室裙部相耦合,所述第一自扩张耳片具有尖端和基部,
其中所述第一自扩张耳片在从其移除约束时径向地自扩张,并且
其中由所述心房裙部的外表面、所述心室裙部的外表面和所述第一耳片的内表面所界定的区域形成容器,并且
其中由所述凸缘的边缘与所述第一耳片的尖端之间的间隙限定窗口,并且
其中当所述第一耳片的尖端不受约束且所述第一耳片的基部至少部分地受约束时,所述间隙最大,并且
其中当所述第一耳片的尖端不受约束且所述第一耳片的基部也不受约束时,所述间隙最小。
2.根据权利要求1所述的假体瓣膜,其中当所述间隙最大时,所述窗口适于在所述容器中接纳瓣膜小叶。
3.根据权利要求1所述的假体瓣膜,其中当所述第一耳片的基部被从约束中释放时,该第一耳片的尖端朝向所述凸缘的边缘移动。
4.根据权利要求1所述的假体瓣膜,其中由所述第一耳片的内表面和所述心室裙部的外表面限定角α,并且其中当所述第一耳片的基部被从约束中释放并且所述第一耳片的尖端不受约束时,α减小。
5.根据权利要求1所述的假体瓣膜,其中由所述第一耳片的内表面和所述心室裙部的外表面限定角α,并且其中当所述第一耳片的尖端不受约束并且所述第一耳片的基部至少部分地受约束时,α最大。
6.根据权利要求1所述的假体,进一步包括连合杆,该连合杆与所述自扩张框架相耦合并具有径向向内延伸的末端,并且其中由该连合杆的外表面和所述心室裙部的内表面限定角β,并且其中当所述第一耳片的基部至少部分地受约束并且所述第一耳片的尖端不受约束时,β最小。
7.根据权利要求1所述的假体,进一步包括连合杆,该连合杆与所述自扩张框架相耦合并具有径向向内延伸的末端,并且其中由该连合杆的外表面和所述心室裙部的内表面限定角β,并且其中当所述第一耳片的基部不受约束并且所述第一耳片的尖端不受约束时,β最大。
8.根据权利要求1所述的假体,进一步包括连合杆,该连合杆与所述自扩张框架相耦合并具有径向向内延伸的末端,其中所述连合杆适于在所述第一耳片的基部和所述第一耳片的尖端不受约束之后保持耦合至递送导管。
9.根据权利要求1所述的假体,进一步包括至少部分地安置在所述自扩张框架上的覆盖物,该覆盖物促进组织长入。
10.根据权利要求1所述的假体,其中当所述自扩张框架处于所述扩张配置时,所述耳片的尖端适于接合纤维三角区。
11.根据权利要求1所述的假体,其中当所述自扩张框架处于所述扩张配置时,所述耳片适于安置在前二尖瓣小叶或后二尖瓣小叶之后。
12.根据权利要求1所述的假体,其中所述心房裙部先于所述第一耳片扩张。
13.根据权利要求1所述的假体,其中在所述第一耳片将所述假体锚固到瓣膜小叶之前,所述心房裙部将所述假体锚固到心房。
14.根据权利要求1所述的假体,其中当所述第一耳片的尖端不受约束并且所述第一耳片的所述基部至少部分地受约束时,所述第一耳片扩张至横向于所述假体的纵轴线的位置。
15.根据权利要求1所述的假体,其中当所述第一耳片的尖端不受约束并且所述第一耳片的所述基部也不受约束时,所述第一耳片扩张至基本上平行于所述假体的纵轴线的位置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261598626P | 2012-02-14 | 2012-02-14 | |
US61/598,626 | 2012-02-14 | ||
CN201380017320.1A CN104203158B (zh) | 2012-02-14 | 2013-02-13 | 用于使瓣膜假体与组织相接合的方法和装置 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201380017320.1A Division CN104203158B (zh) | 2012-02-14 | 2013-02-13 | 用于使瓣膜假体与组织相接合的方法和装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105997305A true CN105997305A (zh) | 2016-10-12 |
CN105997305B CN105997305B (zh) | 2018-11-13 |
Family
ID=48983488
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201380017320.1A Active CN104203158B (zh) | 2012-02-14 | 2013-02-13 | 用于使瓣膜假体与组织相接合的方法和装置 |
CN201610543000.5A Active CN105997305B (zh) | 2012-02-14 | 2013-02-13 | 用于使瓣膜假体与组织相接合的方法和装置 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201380017320.1A Active CN104203158B (zh) | 2012-02-14 | 2013-02-13 | 用于使瓣膜假体与组织相接合的方法和装置 |
Country Status (7)
Country | Link |
---|---|
US (4) | US9554897B2 (zh) |
EP (1) | EP2814429A4 (zh) |
JP (2) | JP6209543B2 (zh) |
CN (2) | CN104203158B (zh) |
AU (2) | AU2013220881B2 (zh) |
CA (2) | CA2864160C (zh) |
WO (1) | WO2013120181A1 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109843219A (zh) * | 2016-08-26 | 2019-06-04 | 爱德华兹生命科学公司 | 多部分置换心脏瓣膜假体 |
CN109843218A (zh) * | 2016-12-02 | 2019-06-04 | 赛诺医疗科学技术股份有限公司 | 低轮廓心脏瓣膜和输送系统 |
CN110177525A (zh) * | 2017-02-01 | 2019-08-27 | 美敦力瓦斯科尔勒公司 | 包括扭矩锚定机构的心脏瓣膜假体和用于心脏瓣膜假体的递送装置 |
Families Citing this family (189)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1951352B1 (en) | 2005-11-10 | 2017-01-11 | Edwards Lifesciences CardiAQ LLC | Balloon-expandable, self-expanding, vascular prosthesis connecting stent |
US8652202B2 (en) | 2008-08-22 | 2014-02-18 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
EP2367505B1 (en) | 2008-09-29 | 2020-08-12 | Edwards Lifesciences CardiAQ LLC | Heart valve |
CN101919753A (zh) | 2009-03-30 | 2010-12-22 | 卡迪万蒂奇医药公司 | 人工主动脉瓣膜或二尖瓣膜的无缝合移植方法和装置 |
EP2810620B1 (en) | 2009-04-15 | 2022-09-14 | Edwards Lifesciences CardiAQ LLC | Vascular implant and delivery system |
US9730790B2 (en) | 2009-09-29 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Replacement valve and method |
US8449599B2 (en) | 2009-12-04 | 2013-05-28 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US8870950B2 (en) | 2009-12-08 | 2014-10-28 | Mitral Tech Ltd. | Rotation-based anchoring of an implant |
US9072603B2 (en) * | 2010-02-24 | 2015-07-07 | Medtronic Ventor Technologies, Ltd. | Mitral prosthesis and methods for implantation |
US20110224785A1 (en) | 2010-03-10 | 2011-09-15 | Hacohen Gil | Prosthetic mitral valve with tissue anchors |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
EP3061422B1 (en) | 2010-06-21 | 2021-11-03 | Edwards Lifesciences CardiAQ LLC | Replacement heart valve |
US9763657B2 (en) | 2010-07-21 | 2017-09-19 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US11653910B2 (en) | 2010-07-21 | 2023-05-23 | Cardiovalve Ltd. | Helical anchor implantation |
US9132009B2 (en) | 2010-07-21 | 2015-09-15 | Mitraltech Ltd. | Guide wires with commissural anchors to advance a prosthetic valve |
US8992604B2 (en) | 2010-07-21 | 2015-03-31 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
CN103491900B (zh) | 2010-12-23 | 2017-03-01 | 托尔福公司 | 用于二尖瓣修复和替换的系统 |
US9155619B2 (en) | 2011-02-25 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
EP2688516B1 (en) * | 2011-03-21 | 2022-08-17 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
CA2840084C (en) | 2011-06-21 | 2019-11-05 | Foundry Newco Xii, Inc. | Prosthetic heart valve devices and associated systems and methods |
US20140324164A1 (en) | 2011-08-05 | 2014-10-30 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US8852272B2 (en) | 2011-08-05 | 2014-10-07 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
EP3417813B1 (en) | 2011-08-05 | 2020-05-13 | Cardiovalve Ltd | Percutaneous mitral valve replacement |
WO2013021374A2 (en) | 2011-08-05 | 2013-02-14 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
EP2755602B1 (en) | 2011-09-12 | 2017-08-09 | Highlife SAS | Transcatheter valve prosthesis |
US10080651B2 (en) | 2011-09-12 | 2018-09-25 | Highlife Sas | Transcatheter valve prosthesis |
US9387075B2 (en) | 2011-09-12 | 2016-07-12 | Highlife Sas | Transcatheter valve prosthesis |
US9763780B2 (en) | 2011-10-19 | 2017-09-19 | Twelve, Inc. | Devices, systems and methods for heart valve replacement |
US11202704B2 (en) | 2011-10-19 | 2021-12-21 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9655722B2 (en) | 2011-10-19 | 2017-05-23 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
CN103889369B (zh) | 2011-10-19 | 2016-09-14 | 托尔福公司 | 用于心脏瓣膜置换术的装置 |
US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
CA2849030C (en) | 2011-10-19 | 2020-10-27 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9168131B2 (en) | 2011-12-09 | 2015-10-27 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US9579198B2 (en) | 2012-03-01 | 2017-02-28 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
US9427315B2 (en) | 2012-04-19 | 2016-08-30 | Caisson Interventional, LLC | Valve replacement systems and methods |
US9011515B2 (en) | 2012-04-19 | 2015-04-21 | Caisson Interventional, LLC | Heart valve assembly systems and methods |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US8628571B1 (en) | 2012-11-13 | 2014-01-14 | Mitraltech Ltd. | Percutaneously-deliverable mechanical valve |
EP4166111A1 (en) | 2013-01-24 | 2023-04-19 | Cardiovalve Ltd. | Ventricularly-anchored prosthetic valves |
US9675451B2 (en) | 2013-02-01 | 2017-06-13 | Medtronic CV Luxembourg S.a.r.l. | Anti-paravalvular leakage component for a transcatheter valve prosthesis |
US10583002B2 (en) * | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
US20140277427A1 (en) | 2013-03-14 | 2014-09-18 | Cardiaq Valve Technologies, Inc. | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US9730791B2 (en) | 2013-03-14 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
US11259923B2 (en) | 2013-03-14 | 2022-03-01 | Jc Medical, Inc. | Methods and devices for delivery of a prosthetic valve |
US11406497B2 (en) | 2013-03-14 | 2022-08-09 | Jc Medical, Inc. | Heart valve prosthesis |
JP2016512077A (ja) | 2013-03-14 | 2016-04-25 | カーディオヴァンテージ・メディカル・インク | 塞栓保護デバイスおよび使用方法 |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US10111747B2 (en) | 2013-05-20 | 2018-10-30 | Twelve, Inc. | Implantable heart valve devices, mitral valve repair devices and associated systems and methods |
US9561103B2 (en) | 2013-07-17 | 2017-02-07 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US9724083B2 (en) | 2013-07-26 | 2017-08-08 | Edwards Lifesciences Cardiaq Llc | Systems and methods for sealing openings in an anatomical wall |
US9421094B2 (en) | 2013-10-23 | 2016-08-23 | Caisson Interventional, LLC | Methods and systems for heart valve therapy |
US10646333B2 (en) * | 2013-10-24 | 2020-05-12 | Medtronic, Inc. | Two-piece valve prosthesis with anchor stent and valve component |
EP3107497B1 (en) | 2014-02-21 | 2020-07-22 | Edwards Lifesciences CardiAQ LLC | Delivery device for controlled deployment of a replacement valve |
US10064719B2 (en) * | 2014-03-11 | 2018-09-04 | Highlife Sas | Transcatheter valve prosthesis |
USD755384S1 (en) | 2014-03-05 | 2016-05-03 | Edwards Lifesciences Cardiaq Llc | Stent |
CN106456328A (zh) | 2014-05-19 | 2017-02-22 | 爱德华兹生命科学卡迪尔克有限责任公司 | 带有环形活瓣的二尖瓣膜替代品 |
FR3021208B1 (fr) * | 2014-05-23 | 2021-03-12 | Thomas Modine | Prothese de valve cardiaque mitrale ou tricuspide |
US9532870B2 (en) * | 2014-06-06 | 2017-01-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US9974647B2 (en) | 2014-06-12 | 2018-05-22 | Caisson Interventional, LLC | Two stage anchor and mitral valve assembly |
WO2016016899A1 (en) | 2014-07-30 | 2016-02-04 | Mitraltech Ltd. | Articulatable prosthetic valve |
EP2979664B1 (en) * | 2014-08-01 | 2019-01-09 | Alvimedica Tibbi Ürünler Sanayi Ve Dis Ticaret A.S | Aortic valve prosthesis, particularly suitable for transcatheter implantation |
US9750607B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
US9750605B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
CN104274259B (zh) * | 2014-10-30 | 2016-06-01 | 宁波健世生物科技有限公司 | 一种带瓣叶夹持装置的人工瓣膜假体 |
EP3226810A4 (en) | 2014-12-04 | 2018-08-15 | Edwards Lifesciences Corporation | Percutaneous clip for repairing a heart valve |
EP3028668A1 (en) * | 2014-12-05 | 2016-06-08 | Nvt Ag | Prosthetic heart valve system and delivery system therefor |
US9439757B2 (en) | 2014-12-09 | 2016-09-13 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
JP2017538540A (ja) * | 2014-12-19 | 2017-12-28 | 杭州啓明医療器械有限公司Venus Medtech (Hangzhou), Inc. | 低侵襲性の鍔付き僧帽弁の置換術 |
US9974651B2 (en) | 2015-02-05 | 2018-05-22 | Mitral Tech Ltd. | Prosthetic valve with axially-sliding frames |
EP3253333B1 (en) | 2015-02-05 | 2024-04-03 | Cardiovalve Ltd | Prosthetic valve with axially-sliding frames |
CN107613908B (zh) | 2015-03-19 | 2020-03-10 | 凯森因特万逊奈尔有限公司 | 用于心脏瓣膜疗法的系统和方法 |
US10441416B2 (en) | 2015-04-21 | 2019-10-15 | Edwards Lifesciences Corporation | Percutaneous mitral valve replacement device |
US10376363B2 (en) | 2015-04-30 | 2019-08-13 | Edwards Lifesciences Cardiaq Llc | Replacement mitral valve, delivery system for replacement mitral valve and methods of use |
US10849746B2 (en) | 2015-05-14 | 2020-12-01 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
AU2016262564B2 (en) | 2015-05-14 | 2020-11-05 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
CN110433010A (zh) | 2015-05-14 | 2019-11-12 | 爱德华兹生命科学公司 | 心脏瓣膜密封装置及其递送装置 |
US10226335B2 (en) | 2015-06-22 | 2019-03-12 | Edwards Lifesciences Cardiaq Llc | Actively controllable heart valve implant and method of controlling same |
US10092400B2 (en) | 2015-06-23 | 2018-10-09 | Edwards Lifesciences Cardiaq Llc | Systems and methods for anchoring and sealing a prosthetic heart valve |
JP7111610B2 (ja) | 2015-08-21 | 2022-08-02 | トゥエルヴ, インコーポレイテッド | 埋込可能な心臓弁デバイス、僧帽弁修復デバイス、ならびに関連するシステム及び方法 |
US10117744B2 (en) | 2015-08-26 | 2018-11-06 | Edwards Lifesciences Cardiaq Llc | Replacement heart valves and methods of delivery |
US10575951B2 (en) | 2015-08-26 | 2020-03-03 | Edwards Lifesciences Cardiaq Llc | Delivery device and methods of use for transapical delivery of replacement mitral valve |
US10350066B2 (en) | 2015-08-28 | 2019-07-16 | Edwards Lifesciences Cardiaq Llc | Steerable delivery system for replacement mitral valve and methods of use |
US10456243B2 (en) | 2015-10-09 | 2019-10-29 | Medtronic Vascular, Inc. | Heart valves prostheses and methods for percutaneous heart valve replacement |
US9872765B2 (en) * | 2015-10-12 | 2018-01-23 | Venus Medtech (Hangzhou) Inc | Mitral valve assembly |
FR3043907A1 (fr) * | 2015-11-23 | 2017-05-26 | Alain Dibie | Assemblage pour le remplacement de la valve atrio-ventriculaire tricuspide |
ES2875921T3 (es) * | 2015-12-22 | 2021-11-11 | Medira Ag | Dispositivo protésico de mejora de coaptación de válvula mitral |
EP3818963A1 (en) | 2015-12-30 | 2021-05-12 | Caisson Interventional, LLC | Systems for heart valve therapy |
CN106943207B (zh) * | 2016-01-07 | 2018-11-06 | 上海市同济医院 | 一种用于穿刺置入的房室瓣瓣膜支架及其输送系统 |
CN105496608A (zh) * | 2016-01-11 | 2016-04-20 | 北京迈迪顶峰医疗科技有限公司 | 一种经导管输送主动脉瓣瓣膜装置 |
EP3407835A4 (en) | 2016-01-29 | 2019-06-26 | Neovasc Tiara Inc. | PROSTHETIC VALVE FOR AVOIDING OBSTRUCTION PREVENTING FLOW |
US10321992B2 (en) | 2016-02-01 | 2019-06-18 | Medtronic, Inc. | Heart valve prostheses having multiple support arms and methods for percutaneous heart valve replacement |
US10531866B2 (en) | 2016-02-16 | 2020-01-14 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
US10835714B2 (en) | 2016-03-21 | 2020-11-17 | Edwards Lifesciences Corporation | Multi-direction steerable handles for steering catheters |
US11219746B2 (en) | 2016-03-21 | 2022-01-11 | Edwards Lifesciences Corporation | Multi-direction steerable handles for steering catheters |
US10799675B2 (en) | 2016-03-21 | 2020-10-13 | Edwards Lifesciences Corporation | Cam controlled multi-direction steerable handles |
DE102016106575A1 (de) * | 2016-04-11 | 2017-10-12 | Biotronik Ag | Herzklappenprothese |
USD815744S1 (en) | 2016-04-28 | 2018-04-17 | Edwards Lifesciences Cardiaq Llc | Valve frame for a delivery system |
CN116172753A (zh) | 2016-04-29 | 2023-05-30 | 美敦力瓦斯科尔勒公司 | 具有带系绳的锚定件的假体心脏瓣膜设备以及相关联的系统和方法 |
EP3791828B1 (en) * | 2016-06-02 | 2022-10-26 | Medtronic Vascular Inc. | Transcatheter valve delivery system with septum hole closure tip assembly |
US11331187B2 (en) | 2016-06-17 | 2022-05-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US10973638B2 (en) | 2016-07-07 | 2021-04-13 | Edwards Lifesciences Corporation | Device and method for treating vascular insufficiency |
US10350062B2 (en) * | 2016-07-21 | 2019-07-16 | Edwards Lifesciences Corporation | Replacement heart valve prosthesis |
GB201613219D0 (en) | 2016-08-01 | 2016-09-14 | Mitraltech Ltd | Minimally-invasive delivery systems |
US10856975B2 (en) | 2016-08-10 | 2020-12-08 | Cardiovalve Ltd. | Prosthetic valve with concentric frames |
USD800908S1 (en) | 2016-08-10 | 2017-10-24 | Mitraltech Ltd. | Prosthetic valve element |
US10646340B2 (en) | 2016-08-19 | 2020-05-12 | Edwards Lifesciences Corporation | Steerable delivery system for replacement mitral valve |
US10758348B2 (en) | 2016-11-02 | 2020-09-01 | Edwards Lifesciences Corporation | Supra and sub-annular mitral valve delivery system |
US10653862B2 (en) | 2016-11-07 | 2020-05-19 | Edwards Lifesciences Corporation | Apparatus for the introduction and manipulation of multiple telescoping catheters |
FR3058631B1 (fr) * | 2016-11-14 | 2019-01-25 | Laboratoires Invalv | Implant de traitement d'une valve biologique |
US10905554B2 (en) | 2017-01-05 | 2021-02-02 | Edwards Lifesciences Corporation | Heart valve coaptation device |
WO2018131042A1 (en) | 2017-01-11 | 2018-07-19 | Mitrassist Medical Ltd. | Heart valve prosthesis |
AU2018203053B2 (en) | 2017-01-23 | 2020-03-05 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
CA3051272C (en) | 2017-01-23 | 2023-08-22 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
EP3372199A1 (en) | 2017-03-08 | 2018-09-12 | Epygon | Delivery system for transcatheter prosthetic heart valves |
EP3558169B1 (en) | 2017-04-18 | 2022-01-19 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
US11224511B2 (en) | 2017-04-18 | 2022-01-18 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
US10575950B2 (en) | 2017-04-18 | 2020-03-03 | Twelve, Inc. | Hydraulic systems for delivering prosthetic heart valve devices and associated methods |
US10702378B2 (en) | 2017-04-18 | 2020-07-07 | Twelve, Inc. | Prosthetic heart valve device and associated systems and methods |
US10433961B2 (en) | 2017-04-18 | 2019-10-08 | Twelve, Inc. | Delivery systems with tethers for prosthetic heart valve devices and associated methods |
US10799312B2 (en) | 2017-04-28 | 2020-10-13 | Edwards Lifesciences Corporation | Medical device stabilizing apparatus and method of use |
US10959846B2 (en) | 2017-05-10 | 2021-03-30 | Edwards Lifesciences Corporation | Mitral valve spacer device |
US10792151B2 (en) | 2017-05-11 | 2020-10-06 | Twelve, Inc. | Delivery systems for delivering prosthetic heart valve devices and associated methods |
US10646338B2 (en) | 2017-06-02 | 2020-05-12 | Twelve, Inc. | Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods |
US10709591B2 (en) | 2017-06-06 | 2020-07-14 | Twelve, Inc. | Crimping device and method for loading stents and prosthetic heart valves |
US10729541B2 (en) | 2017-07-06 | 2020-08-04 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
CN114748212A (zh) | 2017-07-06 | 2022-07-15 | 爱德华兹生命科学公司 | 可操纵轨道递送系统 |
US10786352B2 (en) | 2017-07-06 | 2020-09-29 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US10888421B2 (en) | 2017-09-19 | 2021-01-12 | Cardiovalve Ltd. | Prosthetic heart valve with pouch |
US11304805B2 (en) | 2017-09-19 | 2022-04-19 | Cardiovalve Ltd. | Prosthetic valve with inflatable cuff configured to fill a volume between atrial and ventricular tissue anchors |
US11246704B2 (en) | 2017-08-03 | 2022-02-15 | Cardiovalve Ltd. | Prosthetic heart valve |
US10575948B2 (en) | 2017-08-03 | 2020-03-03 | Cardiovalve Ltd. | Prosthetic heart valve |
US11793633B2 (en) | 2017-08-03 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic heart valve |
US10537426B2 (en) | 2017-08-03 | 2020-01-21 | Cardiovalve Ltd. | Prosthetic heart valve |
EP3672530A4 (en) * | 2017-08-25 | 2021-04-14 | Neovasc Tiara Inc. | SEQUENTIALLY INSERTED TRANSCATHETER MITRAL VALVE PROSTHESIS |
US11051940B2 (en) | 2017-09-07 | 2021-07-06 | Edwards Lifesciences Corporation | Prosthetic spacer device for heart valve |
US11065117B2 (en) | 2017-09-08 | 2021-07-20 | Edwards Lifesciences Corporation | Axisymmetric adjustable device for treating mitral regurgitation |
US11110251B2 (en) | 2017-09-19 | 2021-09-07 | Edwards Lifesciences Corporation | Multi-direction steerable handles for steering catheters |
GB201720803D0 (en) | 2017-12-13 | 2018-01-24 | Mitraltech Ltd | Prosthetic Valve and delivery tool therefor |
CN110013350B (zh) | 2018-01-07 | 2023-06-27 | 苏州杰成医疗科技有限公司 | 假体心脏瓣膜输送系统 |
CN110013356B (zh) | 2018-01-07 | 2023-08-01 | 苏州杰成医疗科技有限公司 | 心脏瓣膜假体递送系统 |
US10076415B1 (en) | 2018-01-09 | 2018-09-18 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
US10105222B1 (en) | 2018-01-09 | 2018-10-23 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
US10238493B1 (en) | 2018-01-09 | 2019-03-26 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
US10231837B1 (en) | 2018-01-09 | 2019-03-19 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
US10245144B1 (en) | 2018-01-09 | 2019-04-02 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
US10159570B1 (en) | 2018-01-09 | 2018-12-25 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
US10111751B1 (en) | 2018-01-09 | 2018-10-30 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
US10973639B2 (en) | 2018-01-09 | 2021-04-13 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
BR112020010855A2 (pt) | 2018-01-09 | 2020-11-10 | Edwards Lifesciences Corporation | dispositivos e procedimentos de reparo de válvula nativa |
US10123873B1 (en) | 2018-01-09 | 2018-11-13 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
US10136993B1 (en) | 2018-01-09 | 2018-11-27 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
GB201800399D0 (en) | 2018-01-10 | 2018-02-21 | Mitraltech Ltd | Temperature-control during crimping of an implant |
CN111818877B (zh) | 2018-01-25 | 2023-12-22 | 爱德华兹生命科学公司 | 在部署后用于辅助置换瓣膜重新捕获和重新定位的递送系统 |
US11051934B2 (en) | 2018-02-28 | 2021-07-06 | Edwards Lifesciences Corporation | Prosthetic mitral valve with improved anchors and seal |
WO2019170698A1 (en) * | 2018-03-08 | 2019-09-12 | Symetis Sa | Implantable valve with attached polymeric components |
WO2019195860A2 (en) | 2018-04-04 | 2019-10-10 | Vdyne, Llc | Devices and methods for anchoring transcatheter heart valve |
US11389297B2 (en) | 2018-04-12 | 2022-07-19 | Edwards Lifesciences Corporation | Mitral valve spacer device |
US11207181B2 (en) | 2018-04-18 | 2021-12-28 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
US11344413B2 (en) | 2018-09-20 | 2022-05-31 | Vdyne, Inc. | Transcatheter deliverable prosthetic heart valves and methods of delivery |
US11278437B2 (en) | 2018-12-08 | 2022-03-22 | Vdyne, Inc. | Compression capable annular frames for side delivery of transcatheter heart valve replacement |
US11071627B2 (en) | 2018-10-18 | 2021-07-27 | Vdyne, Inc. | Orthogonally delivered transcatheter heart valve frame for valve in valve prosthesis |
US10595994B1 (en) | 2018-09-20 | 2020-03-24 | Vdyne, Llc | Side-delivered transcatheter heart valve replacement |
US10321995B1 (en) | 2018-09-20 | 2019-06-18 | Vdyne, Llc | Orthogonally delivered transcatheter heart valve replacement |
US10945844B2 (en) | 2018-10-10 | 2021-03-16 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
US11109969B2 (en) | 2018-10-22 | 2021-09-07 | Vdyne, Inc. | Guidewire delivery of transcatheter heart valve |
US11253359B2 (en) | 2018-12-20 | 2022-02-22 | Vdyne, Inc. | Proximal tab for side-delivered transcatheter heart valves and methods of delivery |
US10653522B1 (en) | 2018-12-20 | 2020-05-19 | Vdyne, Inc. | Proximal tab for side-delivered transcatheter heart valve prosthesis |
US11273032B2 (en) | 2019-01-26 | 2022-03-15 | Vdyne, Inc. | Collapsible inner flow control component for side-deliverable transcatheter heart valve prosthesis |
US11185409B2 (en) | 2019-01-26 | 2021-11-30 | Vdyne, Inc. | Collapsible inner flow control component for side-delivered transcatheter heart valve prosthesis |
MX2021009464A (es) | 2019-02-14 | 2021-09-10 | Edwards Lifesciences Corp | Dispositivos de sellado de valvulas cardiacas y dispositivos de suministro para los mismos. |
WO2020181154A2 (en) * | 2019-03-05 | 2020-09-10 | Vdyne, Inc. | Tricuspid regurgitation control devices for orthogonal transcatheter heart valve prosthesis |
US11173027B2 (en) | 2019-03-14 | 2021-11-16 | Vdyne, Inc. | Side-deliverable transcatheter prosthetic valves and methods for delivering and anchoring the same |
US10758346B1 (en) | 2019-03-14 | 2020-09-01 | Vdyne, Inc. | A2 clip for side-delivered transcatheter mitral valve prosthesis |
US11076956B2 (en) | 2019-03-14 | 2021-08-03 | Vdyne, Inc. | Proximal, distal, and anterior anchoring tabs for side-delivered transcatheter mitral valve prosthesis |
US10631983B1 (en) | 2019-03-14 | 2020-04-28 | Vdyne, Inc. | Distal subannular anchoring tab for side-delivered transcatheter valve prosthesis |
CA3135753C (en) * | 2019-04-01 | 2023-10-24 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
CN113924065A (zh) * | 2019-04-10 | 2022-01-11 | 内奥瓦斯克迪亚拉公司 | 具有自然血流的假体瓣膜 |
WO2020227249A1 (en) | 2019-05-04 | 2020-11-12 | Vdyne, Inc. | Cinch device and method for deployment of a side-delivered prosthetic heart valve in a native annulus |
WO2020257643A1 (en) * | 2019-06-20 | 2020-12-24 | Neovasc Tiara Inc. | Low profile prosthetic mitral valve |
WO2021035032A1 (en) | 2019-08-20 | 2021-02-25 | Vdyne, Inc. | Delivery and retrieval devices and methods for side-deliverable transcatheter prosthetic valves |
JP2022545728A (ja) | 2019-08-26 | 2022-10-28 | ブイダイン,インコーポレイテッド | 側方送達可能な経カテーテル人工弁ならびにそれらを送達及び固定するための方法 |
US11234813B2 (en) | 2020-01-17 | 2022-02-01 | Vdyne, Inc. | Ventricular stability elements for side-deliverable prosthetic heart valves and methods of delivery |
WO2021207695A1 (en) * | 2020-04-09 | 2021-10-14 | Sutra Medical, Inc. | Prosthetic hem i heart valve |
US11938022B2 (en) | 2020-06-26 | 2024-03-26 | Highlife Sas | Transcatheter valve prosthesis and method for implanting the same |
EP4272711A1 (en) * | 2022-05-06 | 2023-11-08 | Epygon | Compressing/loading a cardiovascular implant |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101484093A (zh) * | 2006-06-01 | 2009-07-15 | 爱德华兹生命科学公司 | 用于改善心瓣膜功能的人工插入物 |
WO2011069048A2 (en) * | 2009-12-04 | 2011-06-09 | Edward Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US20110208297A1 (en) * | 2010-02-24 | 2011-08-25 | Medtronic Ventor Technologies Ltd. | Mitral Prosthesis and Methods for Implantation |
CN103079498A (zh) * | 2010-05-05 | 2013-05-01 | 内奥瓦斯克公司 | 经导管二尖瓣假体 |
CN104302247A (zh) * | 2011-11-23 | 2015-01-21 | 内奥瓦斯克迪亚拉公司 | 依次展开的经导管二尖瓣假体 |
Family Cites Families (2040)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB243370A (en) | 1924-11-20 | 1926-08-26 | Charles Choffel | Improvements in or relating to carburettors for internal combustion engines |
GB264572A (en) | 1925-10-19 | 1927-01-19 | Charles Samuel Franklin | Improvements in or relating to aerial systems for use in wireless telegraphy and telephony |
NL246112A (zh) | 1958-01-27 | Eastman Kodak Co | ||
GB1264471A (zh) | 1968-01-12 | 1972-02-23 | ||
US3671979A (en) | 1969-09-23 | 1972-06-27 | Univ Utah | Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve |
US3657744A (en) | 1970-05-08 | 1972-04-25 | Univ Minnesota | Method for fixing prosthetic implants in a living body |
GB1315844A (en) | 1970-05-12 | 1973-05-02 | Nat Res Dev | Prosthetic cardiac valve |
US3739402A (en) | 1970-10-15 | 1973-06-19 | Cutter Lab | Bicuspid fascia lata valve |
AR206762A1 (es) | 1976-01-01 | 1976-08-13 | Pisanu A | Bioprotesis de bajo perfil derivada de la valvula aortica heterologa de porcino |
US4056854A (en) | 1976-09-28 | 1977-11-08 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Aortic heart valve catheter |
GB1603634A (en) | 1977-05-05 | 1981-11-25 | Nat Res Dev | Prosthetic valves |
US4222126A (en) | 1978-12-14 | 1980-09-16 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare | Unitized three leaflet heart valve |
US4265694A (en) | 1978-12-14 | 1981-05-05 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Method of making unitized three leaflet heart valve |
US4340977A (en) | 1980-09-19 | 1982-07-27 | Brownlee Richard T | Catenary mitral valve replacement |
US4339831A (en) | 1981-03-27 | 1982-07-20 | Medtronic, Inc. | Dynamic annulus heart valve and reconstruction ring |
US4470157A (en) | 1981-04-27 | 1984-09-11 | Love Jack W | Tricuspid prosthetic tissue heart valve |
DE3128704A1 (de) | 1981-07-21 | 1983-02-10 | Peter Dr. 5012 Bedburg Küpper | Herzklappenprothese |
US4865600A (en) | 1981-08-25 | 1989-09-12 | Baxter International Inc. | Mitral valve holder |
DE3250058C2 (zh) | 1981-09-16 | 1992-08-27 | Medinvent S.A., Lausanne, Ch | |
DE3365190D1 (en) | 1982-01-20 | 1986-09-18 | Martin Morris Black | Artificial heart valves |
SE445884B (sv) | 1982-04-30 | 1986-07-28 | Medinvent Sa | Anordning for implantation av en rorformig protes |
US4477930A (en) | 1982-09-28 | 1984-10-23 | Mitral Medical International, Inc. | Natural tissue heat valve and method of making same |
US5067957A (en) | 1983-10-14 | 1991-11-26 | Raychem Corporation | Method of inserting medical devices incorporating SIM alloy elements |
US5190546A (en) | 1983-10-14 | 1993-03-02 | Raychem Corporation | Medical devices incorporating SIM alloy elements |
US4733665C2 (en) | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
US4777951A (en) | 1986-09-19 | 1988-10-18 | Mansfield Scientific, Inc. | Procedure and catheter instrument for treating patients for aortic stenosis |
US4950227A (en) | 1988-11-07 | 1990-08-21 | Boston Scientific Corporation | Stent delivery system |
US4994077A (en) | 1989-04-21 | 1991-02-19 | Dobben Richard L | Artificial heart valve for implantation in a blood vessel |
US5439446A (en) | 1994-06-30 | 1995-08-08 | Boston Scientific Corporation | Stent and therapeutic delivery system |
GB2245495A (en) | 1990-05-11 | 1992-01-08 | John Stanley Webber | Artery support insertion instrument |
DK124690D0 (da) | 1990-05-18 | 1990-05-18 | Henning Rud Andersen | Klapprotes til implantering i kroppen for erstatning af naturlig klap samt kateter til brug ved implantering af en saadan klapprotese |
US5411552A (en) | 1990-05-18 | 1995-05-02 | Andersen; Henning R. | Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis |
GB9012716D0 (en) | 1990-06-07 | 1990-08-01 | Frater Robert W M | Mitral heart valve replacements |
US5163955A (en) | 1991-01-24 | 1992-11-17 | Autogenics | Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment |
US5197978B1 (en) | 1991-04-26 | 1996-05-28 | Advanced Coronary Tech | Removable heat-recoverable tissue supporting device |
USD390957S (en) | 1992-03-09 | 1998-02-17 | Cook Incorporated | Implantable intravascular stent |
USD484979S1 (en) | 1991-06-28 | 2004-01-06 | Cook Incorporated | Implantable intravascular stent |
US5795325A (en) | 1991-07-16 | 1998-08-18 | Heartport, Inc. | Methods and apparatus for anchoring an occluding member |
US5370685A (en) | 1991-07-16 | 1994-12-06 | Stanford Surgical Technologies, Inc. | Endovascular aortic valve replacement |
US5769812A (en) | 1991-07-16 | 1998-06-23 | Heartport, Inc. | System for cardiac procedures |
US5332402A (en) | 1992-05-12 | 1994-07-26 | Teitelbaum George P | Percutaneously-inserted cardiac valve |
US6336938B1 (en) | 1992-08-06 | 2002-01-08 | William Cook Europe A/S | Implantable self expanding prosthetic device |
FR2694491B1 (fr) | 1992-08-07 | 1994-09-30 | Celsa Lg | Filtres à pattes triangulées. |
US6074417A (en) | 1992-11-16 | 2000-06-13 | St. Jude Medical, Inc. | Total mitral heterologous bioprosthesis to be used in mitral or tricuspid heart replacement |
US6283127B1 (en) | 1992-12-03 | 2001-09-04 | Wesley D. Sterman | Devices and methods for intracardiac procedures |
US5474563A (en) | 1993-03-25 | 1995-12-12 | Myler; Richard | Cardiovascular stent and retrieval apparatus |
US5843167A (en) | 1993-04-22 | 1998-12-01 | C. R. Bard, Inc. | Method and apparatus for recapture of hooked endoprosthesis |
DE4336899C1 (de) | 1993-10-28 | 1994-12-01 | Novacor Gmbh | Doppelflügel-Herzklappenprothese |
EP0657147B1 (en) | 1993-11-04 | 1999-08-04 | C.R. Bard, Inc. | Non-migrating vascular prosthesis |
US5607444A (en) | 1993-12-02 | 1997-03-04 | Advanced Cardiovascular Systems, Inc. | Ostial stent for bifurcations |
US5509930A (en) | 1993-12-17 | 1996-04-23 | Autogenics | Stentless heart valve |
US5522885A (en) | 1994-05-05 | 1996-06-04 | Autogenics | Assembly tooling for an autologous tissue heart valve |
DE69518435T3 (de) | 1994-06-08 | 2004-07-22 | CardioVascular Concepts, Inc., Portola Valley | System zur Herstellung eines abzweigenden Transplantats |
US5554185A (en) | 1994-07-18 | 1996-09-10 | Block; Peter C. | Inflatable prosthetic cardiovascular valve for percutaneous transluminal implantation of same |
US5397355A (en) | 1994-07-19 | 1995-03-14 | Stentco, Inc. | Intraluminal stent |
US5575818A (en) | 1995-02-14 | 1996-11-19 | Corvita Corporation | Endovascular stent with locking ring |
US6203542B1 (en) | 1995-06-07 | 2001-03-20 | Arthrocare Corporation | Method for electrosurgical treatment of submucosal tissue |
US5807398A (en) | 1995-04-28 | 1998-09-15 | Shaknovich; Alexander | Shuttle stent delivery catheter |
US6602281B1 (en) | 1995-06-05 | 2003-08-05 | Avantec Vascular Corporation | Radially expansible vessel scaffold having beams and expansion joints |
US6231608B1 (en) | 1995-06-07 | 2001-05-15 | Crosscart, Inc. | Aldehyde and glycosidase-treated soft and bone tissue xenografts |
US6837887B2 (en) | 1995-06-07 | 2005-01-04 | Arthrocare Corporation | Articulated electrosurgical probe and methods |
US6149620A (en) | 1995-11-22 | 2000-11-21 | Arthrocare Corporation | System and methods for electrosurgical tissue treatment in the presence of electrically conductive fluid |
US5713952A (en) | 1995-09-11 | 1998-02-03 | St. Jude Medical, Inc. | Apparatus for attachment of heart valve holder to heart valve prosthesis |
WO1997014375A1 (en) | 1995-10-20 | 1997-04-24 | Bandula Wijay | Vascular stent |
US5843117A (en) | 1996-02-14 | 1998-12-01 | Inflow Dynamics Inc. | Implantable vascular and endoluminal stents and process of fabricating the same |
US6402780B2 (en) | 1996-02-23 | 2002-06-11 | Cardiovascular Technologies, L.L.C. | Means and method of replacing a heart valve in a minimally invasive manner |
EP1477133B9 (en) | 1996-03-05 | 2007-11-21 | Evysio Medical Devices Ulc | Expandable stent |
EP0795304B1 (en) | 1996-03-10 | 2004-05-19 | Terumo Kabushiki Kaisha | Implanting stent |
US8036741B2 (en) | 1996-04-30 | 2011-10-11 | Medtronic, Inc. | Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure |
SE510577C2 (sv) | 1996-05-08 | 1999-06-07 | Carag Ag | Anordning vid implantat |
US5855601A (en) | 1996-06-21 | 1999-01-05 | The Trustees Of Columbia University In The City Of New York | Artificial heart valve and method and device for implanting the same |
DE19625202A1 (de) | 1996-06-24 | 1998-01-02 | Adiam Medizintechnik Gmbh & Co | Prothetische Mitral-Herzklappe |
DE19624948A1 (de) | 1996-06-24 | 1998-01-02 | Adiam Medizintechnik Gmbh & Co | Prothetische Herzklappe |
US5669919A (en) | 1996-08-16 | 1997-09-23 | Medtronic, Inc. | Annuloplasty system |
US5954764A (en) | 1996-09-20 | 1999-09-21 | Parodi; Juan Carlos | Device for concurrently placing an endovascular expander with an endovascular prosthesis |
US5725519A (en) | 1996-09-30 | 1998-03-10 | Medtronic Instent Israel Ltd. | Stent loading device for a balloon catheter |
US6315791B1 (en) | 1996-12-03 | 2001-11-13 | Atrium Medical Corporation | Self-expanding prothesis |
NL1004827C2 (nl) | 1996-12-18 | 1998-06-19 | Surgical Innovations Vof | Inrichting voor het reguleren van de bloedsomloop. |
US7073504B2 (en) | 1996-12-18 | 2006-07-11 | Ams Research Corporation | Contraceptive system and method of use |
US6015431A (en) | 1996-12-23 | 2000-01-18 | Prograft Medical, Inc. | Endolumenal stent-graft with leak-resistant seal |
US5868782A (en) | 1996-12-24 | 1999-02-09 | Global Therapeutics, Inc. | Radially expandable axially non-contracting surgical stent |
EP0850607A1 (en) | 1996-12-31 | 1998-07-01 | Cordis Corporation | Valve prosthesis for implantation in body channels |
US6045497A (en) | 1997-01-02 | 2000-04-04 | Myocor, Inc. | Heart wall tension reduction apparatus and method |
US6183411B1 (en) | 1998-09-21 | 2001-02-06 | Myocor, Inc. | External stress reduction device and method |
US8353948B2 (en) | 1997-01-24 | 2013-01-15 | Celonova Stent, Inc. | Fracture-resistant helical stent incorporating bistable cells and methods of use |
US7241309B2 (en) | 1999-04-15 | 2007-07-10 | Scimed Life Systems, Inc. | Self-aggregating protein compositions and use as sealants |
US5928281A (en) | 1997-03-27 | 1999-07-27 | Baxter International Inc. | Tissue heart valves |
US5957949A (en) | 1997-05-01 | 1999-09-28 | World Medical Manufacturing Corp. | Percutaneous placement valve stent |
US6395024B1 (en) | 1997-05-20 | 2002-05-28 | Triflo Medical, Inc. | Mechanical heart valve |
US6168616B1 (en) | 1997-06-02 | 2001-01-02 | Global Vascular Concepts | Manually expandable stent |
US6004328A (en) | 1997-06-19 | 1999-12-21 | Solar; Ronald J. | Radially expandable intraluminal stent and delivery catheter therefore and method of using the same |
US5810873A (en) | 1997-07-15 | 1998-09-22 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool and method of use |
US6613278B1 (en) | 1998-11-13 | 2003-09-02 | Regeneration Technologies, Inc. | Tissue pooling process |
US8257725B2 (en) | 1997-09-26 | 2012-09-04 | Abbott Laboratories | Delivery of highly lipophilic agents via medical devices |
US6042606A (en) | 1997-09-29 | 2000-03-28 | Cook Incorporated | Radially expandable non-axially contracting surgical stent |
US5992000A (en) | 1997-10-16 | 1999-11-30 | Scimed Life Systems, Inc. | Stent crimper |
US5935108A (en) | 1997-11-14 | 1999-08-10 | Reflow, Inc. | Recanalization apparatus and devices for use therein and method |
US6530952B2 (en) | 1997-12-29 | 2003-03-11 | The Cleveland Clinic Foundation | Bioprosthetic cardiovascular valve system |
US6352543B1 (en) | 2000-04-29 | 2002-03-05 | Ventrica, Inc. | Methods for forming anastomoses using magnetic force |
ATE333896T1 (de) | 1998-03-24 | 2006-08-15 | Chugai Pharmaceutical Co Ltd | Vaskularisierungsinhibitoren |
US20040254635A1 (en) | 1998-03-30 | 2004-12-16 | Shanley John F. | Expandable medical device for delivery of beneficial agent |
US7208011B2 (en) | 2001-08-20 | 2007-04-24 | Conor Medsystems, Inc. | Implantable medical device with drug filled holes |
US6520983B1 (en) | 1998-03-31 | 2003-02-18 | Scimed Life Systems, Inc. | Stent delivery system |
US7713297B2 (en) | 1998-04-11 | 2010-05-11 | Boston Scientific Scimed, Inc. | Drug-releasing stent with ceramic-containing layer |
US7658727B1 (en) | 1998-04-20 | 2010-02-09 | Medtronic, Inc | Implantable medical device with enhanced biocompatibility and biostability |
US6221104B1 (en) | 1998-05-01 | 2001-04-24 | Cor Restore, Inc. | Anterior and interior segment cardiac restoration apparatus and method |
US6132458A (en) | 1998-05-15 | 2000-10-17 | American Medical Systems, Inc. | Method and device for loading a stent |
US6613059B2 (en) | 1999-03-01 | 2003-09-02 | Coalescent Surgical, Inc. | Tissue connector apparatus and methods |
US6250308B1 (en) | 1998-06-16 | 2001-06-26 | Cardiac Concepts, Inc. | Mitral valve annuloplasty ring and method of implanting |
ATE281796T1 (de) | 1998-07-13 | 2004-11-15 | Acorn Cardiovascular Inc | Vorrichtung zur behandlung von herzkrankheiten |
US7569062B1 (en) | 1998-07-15 | 2009-08-04 | St. Jude Medical, Inc. | Mitral and tricuspid valve repair |
EP2111800B1 (en) | 1998-07-29 | 2016-06-15 | Edwards Lifesciences AG | Transventricular implant tools and devices |
US6260552B1 (en) | 1998-07-29 | 2001-07-17 | Myocor, Inc. | Transventricular implant tools and devices |
US6406488B1 (en) | 1998-08-27 | 2002-06-18 | Heartstent Corporation | Healing transmyocardial implant |
US7118600B2 (en) | 1998-08-31 | 2006-10-10 | Wilson-Cook Medical, Inc. | Prosthesis having a sleeve valve |
US6641610B2 (en) | 1998-09-10 | 2003-11-04 | Percardia, Inc. | Valve designs for left ventricular conduits |
WO2000015147A1 (en) | 1998-09-10 | 2000-03-23 | Percardia, Inc. | Transmycardial shunt and its attachment mechanism, for left ventricular revascularization |
ATE322230T1 (de) | 1998-09-10 | 2006-04-15 | Percardia Inc | Tmr vorrichtung |
US6254564B1 (en) | 1998-09-10 | 2001-07-03 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
US6214054B1 (en) | 1998-09-21 | 2001-04-10 | Edwards Lifesciences Corporation | Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
US8257724B2 (en) | 1998-09-24 | 2012-09-04 | Abbott Laboratories | Delivery of highly lipophilic agents via medical devices |
US6200341B1 (en) | 1998-09-25 | 2001-03-13 | Sulzer Carbomedics Inc. | Mechanical heart valve assembly with super-elastic lock wire |
US6458092B1 (en) | 1998-09-30 | 2002-10-01 | C. R. Bard, Inc. | Vascular inducing implants |
US6248112B1 (en) | 1998-09-30 | 2001-06-19 | C. R. Bard, Inc. | Implant delivery system |
DE69922228T2 (de) | 1998-09-30 | 2005-12-01 | Medtronic, Inc., Minneapolis | Verfahren zur Reduzierung der Mineralisierung von Gewebe zum Gebrauch bei Transplantationen |
US6432126B1 (en) | 1998-09-30 | 2002-08-13 | C.R. Bard, Inc. | Flexible vascular inducing implants |
US6475239B1 (en) | 1998-10-13 | 2002-11-05 | Sulzer Carbomedics Inc. | Method for making polymer heart valves with leaflets having uncut free edges |
US6102945A (en) | 1998-10-16 | 2000-08-15 | Sulzer Carbomedics, Inc. | Separable annuloplasty ring |
EP1124592B1 (en) | 1998-10-28 | 2006-06-07 | Cellon S.A. | Textured and porous silicone rubber |
BE1012536A3 (fr) | 1998-11-04 | 2000-12-05 | Baxter Int | Element muni d'une couche de fibrine sa preparation et son utilisation. |
US6152937A (en) | 1998-11-06 | 2000-11-28 | St. Jude Medical Cardiovascular Group, Inc. | Medical graft connector and methods of making and installing same |
US6113612A (en) | 1998-11-06 | 2000-09-05 | St. Jude Medical Cardiovascular Group, Inc. | Medical anastomosis apparatus |
US6001056A (en) | 1998-11-13 | 1999-12-14 | Baxter International Inc. | Smooth ventricular assist device conduit |
US6322585B1 (en) | 1998-11-16 | 2001-11-27 | Endotex Interventional Systems, Inc. | Coiled-sheet stent-graft with slidable exo-skeleton |
US6540780B1 (en) | 1998-11-23 | 2003-04-01 | Medtronic, Inc. | Porous synthetic vascular grafts with oriented ingrowth channels |
US6733523B2 (en) | 1998-12-11 | 2004-05-11 | Endologix, Inc. | Implantable vascular graft |
US6692520B1 (en) | 1998-12-15 | 2004-02-17 | C. R. Bard, Inc. | Systems and methods for imbedded intramuscular implants |
AU2583200A (en) | 1998-12-28 | 2000-07-31 | Andrei Vasilievich Agafonov | Heart valve prosthesis |
WO2000042951A1 (en) | 1999-01-26 | 2000-07-27 | Edwards Lifesciences Corporation | Anatomical orifice sizers and methods of orifice sizing |
EP1990024A3 (en) | 1999-01-26 | 2014-05-28 | Edwards Lifesciences Corporation | Flexible heart valve |
US6896690B1 (en) | 2000-01-27 | 2005-05-24 | Viacor, Inc. | Cardiac valve procedure methods and devices |
ATE465693T1 (de) | 1999-01-27 | 2010-05-15 | Medtronic Inc | Vorrichtung für herzklappeneingriffe |
US7018401B1 (en) | 1999-02-01 | 2006-03-28 | Board Of Regents, The University Of Texas System | Woven intravascular devices and methods for making the same and apparatus for delivery of the same |
DE19904975A1 (de) | 1999-02-06 | 2000-09-14 | Impella Cardiotech Ag | Vorrichtung zur intravasalen Herzklappenoperation |
US6425916B1 (en) | 1999-02-10 | 2002-07-30 | Michi E. Garrison | Methods and devices for implanting cardiac valves |
US20030068815A1 (en) | 1999-02-11 | 2003-04-10 | Stone Kevin R. | Sterilized xenograft tissue |
NO308575B1 (no) | 1999-02-17 | 2000-10-02 | Sumit Roy | Flerbruksventil |
AU3729400A (en) | 1999-03-09 | 2000-09-28 | St. Jude Medical Cardiovascular Group, Inc. | Medical grafting methods and apparatus |
DE19910233A1 (de) | 1999-03-09 | 2000-09-21 | Jostra Medizintechnik Ag | Anuloplastieprothese |
US6325825B1 (en) | 1999-04-08 | 2001-12-04 | Cordis Corporation | Stent with variable wall thickness |
ATE484241T1 (de) | 1999-04-09 | 2010-10-15 | Evalve Inc | Verfahren und vorrichtung zur herzklappenreperation |
US8216256B2 (en) | 1999-04-09 | 2012-07-10 | Evalve, Inc. | Detachment mechanism for implantable fixation devices |
US6752813B2 (en) | 1999-04-09 | 2004-06-22 | Evalve, Inc. | Methods and devices for capturing and fixing leaflets in valve repair |
US7563267B2 (en) | 1999-04-09 | 2009-07-21 | Evalve, Inc. | Fixation device and methods for engaging tissue |
US20040044350A1 (en) | 1999-04-09 | 2004-03-04 | Evalve, Inc. | Steerable access sheath and methods of use |
US6231602B1 (en) | 1999-04-16 | 2001-05-15 | Edwards Lifesciences Corporation | Aortic annuloplasty ring |
US7147663B1 (en) | 1999-04-23 | 2006-12-12 | St. Jude Medical Atg, Inc. | Artificial heart valve attachment apparatus and methods |
AU4242800A (en) | 1999-04-23 | 2000-11-10 | St. Jude Medical Cardiovascular Group, Inc. | Artificial heart valve attachment apparatus |
US6620170B1 (en) | 1999-04-26 | 2003-09-16 | C. R. Bard, Inc. | Devices and methods for treating ischemia by creating a fibrin plug |
DE60035495T2 (de) | 1999-04-28 | 2008-03-20 | St. Jude Medical, Inc., St. Paul | Aortenherzklappenprothesenmess- und -markierungsvorrichtung |
DE19919625C2 (de) | 1999-04-29 | 2002-10-31 | Symetis Ag Zuerich | In-vitro-Verfahren zum Herstellen einer homologen Herzklappe und durch dieses Verfahren herstellbare Klappe |
US6245101B1 (en) | 1999-05-03 | 2001-06-12 | William J. Drasler | Intravascular hinge stent |
US6712836B1 (en) | 1999-05-13 | 2004-03-30 | St. Jude Medical Atg, Inc. | Apparatus and methods for closing septal defects and occluding blood flow |
WO2000069504A1 (en) | 1999-05-14 | 2000-11-23 | C.R. Bard, Inc. | Agent delivery systems |
US6858034B1 (en) | 1999-05-20 | 2005-02-22 | Scimed Life Systems, Inc. | Stent delivery system for prevention of kinking, and method of loading and using same |
US6790229B1 (en) | 1999-05-25 | 2004-09-14 | Eric Berreklouw | Fixing device, in particular for fixing to vascular wall tissue |
US6669687B1 (en) | 1999-06-25 | 2003-12-30 | Vahid Saadat | Apparatus and methods for treating tissue |
SE514718C2 (sv) | 1999-06-29 | 2001-04-09 | Jan Otto Solem | Anordning för behandling av bristande tillslutningsförmåga hos mitralisklaffapparaten |
US7192442B2 (en) | 1999-06-30 | 2007-03-20 | Edwards Lifesciences Ag | Method and device for treatment of mitral insufficiency |
US6312465B1 (en) | 1999-07-23 | 2001-11-06 | Sulzer Carbomedics Inc. | Heart valve prosthesis with a resiliently deformable retaining member |
US6610071B1 (en) | 1999-07-26 | 2003-08-26 | Beth Israel Deaconess Medical Center | Suture system |
AU6530800A (en) | 1999-08-05 | 2001-03-05 | Broncus Technologies, Inc. | Methods and devices for creating collateral channels in the lungs |
US6749606B2 (en) | 1999-08-05 | 2004-06-15 | Thomas Keast | Devices for creating collateral channels |
US7022088B2 (en) | 1999-08-05 | 2006-04-04 | Broncus Technologies, Inc. | Devices for applying energy to tissue |
US6293951B1 (en) | 1999-08-24 | 2001-09-25 | Spiration, Inc. | Lung reduction device, system, and method |
US6350281B1 (en) | 1999-09-14 | 2002-02-26 | Edwards Lifesciences Corp. | Methods and apparatus for measuring valve annuluses during heart valve-replacement surgery |
AU771470B2 (en) | 1999-09-20 | 2004-03-25 | Atritech, Inc. | Method and apparatus for closing a body lumen |
EP1214106B1 (en) | 1999-09-22 | 2003-11-19 | Baxter International Inc. | Cardiac valve and method for preparing a biological tissue |
US6358278B1 (en) | 1999-09-24 | 2002-03-19 | St. Jude Medical, Inc. | Heart valve prosthesis with rotatable cuff |
IT1307268B1 (it) | 1999-09-30 | 2001-10-30 | Sorin Biomedica Cardio Spa | Dispositivo per interventi di riparazione o sostituzione valvolarecardiaca. |
US6371983B1 (en) | 1999-10-04 | 2002-04-16 | Ernest Lane | Bioprosthetic heart valve |
US6416547B1 (en) | 1999-10-06 | 2002-07-09 | Edwards Lifesciences Corporation | Heart valve carrier and rinse cage |
FR2799364B1 (fr) | 1999-10-12 | 2001-11-23 | Jacques Seguin | Dispositif d'annuloplastie utilisable par voie mini-invasive |
US20010047200A1 (en) | 1999-10-13 | 2001-11-29 | Raymond Sun | Non-foreshortening intraluminal prosthesis |
CA2286929A1 (en) | 1999-10-18 | 2001-04-18 | Anthony Paolitto | Valve surgery apparatus |
US6440164B1 (en) | 1999-10-21 | 2002-08-27 | Scimed Life Systems, Inc. | Implantable prosthetic valve |
JP2001120582A (ja) | 1999-10-22 | 2001-05-08 | Gunze Ltd | 人工心臓弁およびその作製方法 |
US6551303B1 (en) | 1999-10-27 | 2003-04-22 | Atritech, Inc. | Barrier device for ostium of left atrial appendage |
GB9925636D0 (en) | 1999-10-29 | 1999-12-29 | Angiomed Ag | Method of, and device for, installing a stent in a sleeve |
AU1068800A (en) | 1999-11-10 | 2001-06-06 | Impsa International Incorporated | Prosthetic heart valve |
US8016877B2 (en) | 1999-11-17 | 2011-09-13 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
US7018406B2 (en) | 1999-11-17 | 2006-03-28 | Corevalve Sa | Prosthetic valve for transluminal delivery |
US20070043435A1 (en) | 1999-11-17 | 2007-02-22 | Jacques Seguin | Non-cylindrical prosthetic valve system for transluminal delivery |
US8579966B2 (en) | 1999-11-17 | 2013-11-12 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
FR2815844B1 (fr) | 2000-10-31 | 2003-01-17 | Jacques Seguin | Support tubulaire de mise en place, par voie percutanee, d'une valve cardiaque de remplacement |
FR2800984B1 (fr) | 1999-11-17 | 2001-12-14 | Jacques Seguin | Dispositif de remplacement d'une valve cardiaque par voie percutanee |
US7195641B2 (en) | 1999-11-19 | 2007-03-27 | Advanced Bio Prosthetic Surfaces, Ltd. | Valvular prostheses having metal or pseudometallic construction and methods of manufacture |
US6458153B1 (en) | 1999-12-31 | 2002-10-01 | Abps Venture One, Ltd. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US6280466B1 (en) | 1999-12-03 | 2001-08-28 | Teramed Inc. | Endovascular graft system |
GB0114345D0 (en) | 2001-06-13 | 2001-08-08 | Aortech Europ Ltd | Heart valve prosthesis and method of manufacture |
GB9928905D0 (en) | 1999-12-08 | 2000-02-02 | Aortech Europ Ltd | Prosthesis |
US7632309B1 (en) | 1999-12-13 | 2009-12-15 | St. Jude Medical, Inc. | Pyrolytic carbon and metal/metalloid carbide composites |
SE514886C2 (sv) | 1999-12-14 | 2001-05-14 | Jcl Technic Ab | Kärlventil, såsom hjärtklaff,samt förfarande för dess framställning |
AU2435801A (en) | 1999-12-23 | 2001-07-09 | Edwards Lifesciences Corporation | Enhanced visualization of medical implants |
NL1014095C2 (nl) | 2000-01-17 | 2001-07-18 | Cornelis Hendrikus Anna Witten | Implantaatklep voor implantatie in een bloedvat. |
US8241274B2 (en) | 2000-01-19 | 2012-08-14 | Medtronic, Inc. | Method for guiding a medical device |
CA2397377A1 (en) | 2000-01-25 | 2001-08-02 | Edwards Lifesciences Corporation | Bioactive coatings to prevent tissue overgrowth on artificial heart valves |
MXPA02007253A (es) | 2000-01-27 | 2003-09-22 | 3F Therapeutics Inc | Valvula cardiaca protesica. |
US7749245B2 (en) | 2000-01-27 | 2010-07-06 | Medtronic, Inc. | Cardiac valve procedure methods and devices |
US6872226B2 (en) | 2001-01-29 | 2005-03-29 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
DE60128069D1 (de) | 2000-01-31 | 2007-06-06 | Cook Biotech Inc | Stentventilklappen |
EP1900343B1 (en) | 2000-01-31 | 2015-10-21 | Cook Biotech Incorporated | Stent valves |
US7296577B2 (en) | 2000-01-31 | 2007-11-20 | Edwards Lifescience Ag | Transluminal mitral annuloplasty with active anchoring |
US6402781B1 (en) | 2000-01-31 | 2002-06-11 | Mitralife | Percutaneous mitral annuloplasty and cardiac reinforcement |
DE60111184T2 (de) | 2000-02-02 | 2005-10-27 | Robert V. Snyders | Künstiche herzklappe |
US6797002B2 (en) | 2000-02-02 | 2004-09-28 | Paul A. Spence | Heart valve repair apparatus and methods |
CA2397746C (en) | 2000-02-03 | 2010-07-27 | Cook Incorporated | Implantable vascular device |
DE10010073B4 (de) | 2000-02-28 | 2005-12-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verankerung für implantierbare Herzklappenprothesen |
DE10010074B4 (de) | 2000-02-28 | 2005-04-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung zur Befestigung und Verankerung von Herzklappenprothesen |
US6378221B1 (en) | 2000-02-29 | 2002-04-30 | Edwards Lifesciences Corporation | Systems and methods for mapping and marking the thickness of bioprosthetic sheet |
CA2401996C (en) | 2000-03-03 | 2009-12-08 | Patricia E. Thorpe | Bulbous valve and stent for treating vascular reflux |
US6679264B1 (en) | 2000-03-04 | 2004-01-20 | Emphasys Medical, Inc. | Methods and devices for use in performing pulmonary procedures |
AU2001238383A1 (en) | 2000-03-10 | 2001-09-24 | Paracor Surgical, Inc. | Expandable cardiac harness for treating congestive heart failure |
AU2001245734A1 (en) | 2000-03-15 | 2001-09-24 | Orbus Medical Technologies Inc. | Coating that promotes endothelial cell adherence |
US6537198B1 (en) | 2000-03-21 | 2003-03-25 | Myocor, Inc. | Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly |
IL153753A0 (en) | 2002-12-30 | 2003-07-06 | Neovasc Medical Ltd | Varying-diameter vascular implant and balloon |
US6953476B1 (en) | 2000-03-27 | 2005-10-11 | Neovasc Medical Ltd. | Device and method for treating ischemic heart disease |
US6478776B1 (en) | 2000-04-05 | 2002-11-12 | Biocardia, Inc. | Implant delivery catheter system and methods for its use |
US6454799B1 (en) | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
US6517573B1 (en) | 2000-04-11 | 2003-02-11 | Endovascular Technologies, Inc. | Hook for attaching to a corporeal lumen and method of manufacturing |
US20020049490A1 (en) | 2000-04-11 | 2002-04-25 | Pollock David T. | Single-piece endoprosthesis with high expansion ratios |
ITPC20000013A1 (it) | 2000-04-13 | 2000-07-13 | Paolo Ferrazzi | Dispositivo endoventricolare e metodo relativo per il trattamento e la correzione di miocardiopatie. |
DE50115407D1 (de) | 2000-04-27 | 2010-05-06 | Corlife Gbr | Individuelle venenklappenprothese |
US6610088B1 (en) | 2000-05-03 | 2003-08-26 | Shlomo Gabbay | Biologically covered heart valve prosthesis |
US8252044B1 (en) | 2000-11-17 | 2012-08-28 | Advanced Bio Prosthestic Surfaces, Ltd. | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
US8632583B2 (en) | 2011-05-09 | 2014-01-21 | Palmaz Scientific, Inc. | Implantable medical device having enhanced endothelial migration features and methods of making the same |
US6419695B1 (en) | 2000-05-22 | 2002-07-16 | Shlomo Gabbay | Cardiac prosthesis for helping improve operation of a heart valve |
SI1284688T1 (sl) | 2000-05-25 | 2006-04-30 | Bioring Sa | Priprava za zozitev in/ali ojacitev odprtin in srcnih zaklopk |
US8366769B2 (en) | 2000-06-01 | 2013-02-05 | Edwards Lifesciences Corporation | Low-profile, pivotable heart valve sewing ring |
US6902522B1 (en) | 2000-06-12 | 2005-06-07 | Acorn Cardiovascular, Inc. | Cardiac disease treatment and device |
US6358277B1 (en) | 2000-06-21 | 2002-03-19 | The International Heart Institute Of Montana Foundation | Atrio-ventricular valvular device |
EP1330189B1 (en) | 2000-06-23 | 2007-12-19 | Viacor Incorporated | Automated annular plication for mitral valve repair |
US6527800B1 (en) | 2000-06-26 | 2003-03-04 | Rex Medical, L.P. | Vascular device and method for valve leaflet apposition |
EP1512383B1 (en) | 2000-06-26 | 2013-02-20 | Rex Medical, L.P. | A vascular system for valve leaflet apposition |
US6695878B2 (en) | 2000-06-26 | 2004-02-24 | Rex Medical, L.P. | Vascular device for valve leaflet apposition |
US6676698B2 (en) | 2000-06-26 | 2004-01-13 | Rex Medicol, L.P. | Vascular device with valve for approximating vessel wall |
EP1401358B1 (en) | 2000-06-30 | 2016-08-17 | Medtronic, Inc. | Apparatus for performing a procedure on a cardiac valve |
US7077861B2 (en) | 2000-07-06 | 2006-07-18 | Medtentia Ab | Annuloplasty instrument |
US6419696B1 (en) | 2000-07-06 | 2002-07-16 | Paul A. Spence | Annuloplasty devices and related heart valve repair methods |
ES2249459T3 (es) | 2000-07-11 | 2006-04-01 | Alessandro Verona | Biomaterial que incluye tejido de cornea animal. |
DE60125177T2 (de) | 2000-07-12 | 2007-03-29 | Edwards Lifesciences Corp., Irvine | Verfahren und vorrichtung zum formen einer drahtform für eine herzklappenprothese |
DE10033858B4 (de) | 2000-07-12 | 2006-01-26 | Max Hauser Süddeutsche Chirurgiemechanik GmbH | Vorrichtung zum Spreizen von Gewebe, Gewebeteilen, Organen, Knochen oder anderen Körperteilen bei chirurgischen Eingriffen in menschlichen oder tierischen Körpern |
US6409758B2 (en) | 2000-07-27 | 2002-06-25 | Edwards Lifesciences Corporation | Heart valve holder for constricting the valve commissures and methods of use |
US7399271B2 (en) | 2004-01-09 | 2008-07-15 | Cardiokinetix, Inc. | Ventricular partitioning device |
US7862500B2 (en) | 2002-08-01 | 2011-01-04 | Cardiokinetix, Inc. | Multiple partitioning devices for heart treatment |
EP1179353A1 (de) | 2000-08-11 | 2002-02-13 | B. Braun Melsungen Ag | Antithrombogene Implantate mit Beschichtung aus Polyphosphazenen und einem pharmakologisch aktiven Wirkstoff |
ATE323517T1 (de) | 2000-08-15 | 2006-05-15 | Surmodics Inc | Matrix zur aufnahme von arzneimitteln |
US6572652B2 (en) | 2000-08-29 | 2003-06-03 | Venpro Corporation | Method and devices for decreasing elevated pulmonary venous pressure |
US6458155B1 (en) | 2000-09-01 | 2002-10-01 | Edwards Lifesciences Corporation | Fresh donor heart valve sizer and method of use |
AU2001287144A1 (en) | 2000-09-07 | 2002-03-22 | Viacor, Inc. | Fixation band for affixing a prosthetic heart valve to tissue |
US7510572B2 (en) | 2000-09-12 | 2009-03-31 | Shlomo Gabbay | Implantation system for delivery of a heart valve prosthesis |
WO2002022054A1 (en) | 2000-09-12 | 2002-03-21 | Gabbay S | Valvular prosthesis and method of using same |
DE10046550A1 (de) | 2000-09-19 | 2002-03-28 | Adiam Life Science Ag | Prothetische Mitral-Herzklappe |
US8956407B2 (en) | 2000-09-20 | 2015-02-17 | Mvrx, Inc. | Methods for reshaping a heart valve annulus using a tensioning implant |
US8784482B2 (en) | 2000-09-20 | 2014-07-22 | Mvrx, Inc. | Method of reshaping a heart valve annulus using an intravascular device |
US6893459B1 (en) | 2000-09-20 | 2005-05-17 | Ample Medical, Inc. | Heart valve annulus device and method of using same |
US7527646B2 (en) | 2000-09-20 | 2009-05-05 | Ample Medical, Inc. | Devices, systems, and methods for retaining a native heart valve leaflet |
CA2420049C (en) | 2000-09-21 | 2010-08-24 | St. Jude Medical, Inc. | Valved prostheses with reinforced polymer leaflets |
US6461382B1 (en) | 2000-09-22 | 2002-10-08 | Edwards Lifesciences Corporation | Flexible heart valve having moveable commissures |
US6602288B1 (en) | 2000-10-05 | 2003-08-05 | Edwards Lifesciences Corporation | Minimally-invasive annuloplasty repair segment delivery template, system and method of use |
US6616684B1 (en) | 2000-10-06 | 2003-09-09 | Myocor, Inc. | Endovascular splinting devices and methods |
AU2001296716A1 (en) | 2000-10-13 | 2002-04-22 | Rex Medical, Lp | Covered stents with side branch |
DE60115821T2 (de) | 2000-10-13 | 2006-08-31 | Medtronic AVE, Inc., Santa Rosa | Hydraulisches Stenteinbringungssystem |
WO2002032496A1 (en) | 2000-10-18 | 2002-04-25 | Nmt Medical, Inc. | Over-the-wire interlock attachment/detachment mechanism |
US6602286B1 (en) | 2000-10-26 | 2003-08-05 | Ernst Peter Strecker | Implantable valve system |
EP1339356B1 (en) | 2000-10-30 | 2005-04-13 | Children's Medical Center Corporation | Tissue-engineered vascular structures |
US6482228B1 (en) | 2000-11-14 | 2002-11-19 | Troy R. Norred | Percutaneous aortic valve replacement |
AU2002217770A1 (en) | 2000-11-16 | 2002-05-27 | Geoff Briggs | Automatic suture fixation apparatus and method |
WO2002041789A2 (en) | 2000-11-21 | 2002-05-30 | Rex Medical, L.P. | Percutaneous aortic valve |
US6974476B2 (en) | 2003-05-05 | 2005-12-13 | Rex Medical, L.P. | Percutaneous aortic valve |
US6953332B1 (en) | 2000-11-28 | 2005-10-11 | St. Jude Medical, Inc. | Mandrel for use in forming valved prostheses having polymer leaflets by dip coating |
DE10060660A1 (de) | 2000-12-06 | 2002-06-20 | Frey Rainer | Verfahren zur Konservierung von biologischen Prothesen, konservierte biologische Prothese und Konservierungslösung |
ES2253325T3 (es) | 2000-12-15 | 2006-06-01 | ANGIOMED GMBH & CO. MEDIZINTECHNIK KG | Protesis endovascular con valvula. |
DE10064948C1 (de) | 2000-12-20 | 2002-07-11 | Auto Tissue Gmbh | Verfahren zur Dezellularisierung von Fremdmaterial zur Herstellung von Bioprothesen und Vorrichtung zur Durchführung des Verfahrens |
US6964682B2 (en) | 2000-12-21 | 2005-11-15 | Edwards Lifesciences Corporation | Heart valve holder that resist suture looping |
US6929660B1 (en) | 2000-12-22 | 2005-08-16 | Advanced Cardiovascular Systems, Inc. | Intravascular stent |
DE10065824B4 (de) | 2000-12-28 | 2018-10-31 | Jotec Gmbh | Endovaskulärer Stent zur Implantation in den aufsteigenden Ast der Aorta |
US7591826B2 (en) | 2000-12-28 | 2009-09-22 | Cardiac Dimensions, Inc. | Device implantable in the coronary sinus to provide mitral valve therapy |
US7208002B2 (en) | 2001-01-04 | 2007-04-24 | Boston Scientific Scimed, Inc. | Expansion-assisting delivery system for self-expanding stent |
JP4195612B2 (ja) | 2001-01-30 | 2008-12-10 | エドワーズ ライフサイエンシーズ アーゲー | 管外組織構造を改善する医療システム及び方法 |
US20050182483A1 (en) | 2004-02-11 | 2005-08-18 | Cook Incorporated | Percutaneously placed prosthesis with thromboresistant valve portion |
US6941950B2 (en) | 2001-10-11 | 2005-09-13 | Emphasys Medical, Inc. | Bronchial flow control devices and methods of use |
US6955689B2 (en) | 2001-03-15 | 2005-10-18 | Medtronic, Inc. | Annuloplasty band and method |
US6503272B2 (en) | 2001-03-21 | 2003-01-07 | Cordis Corporation | Stent-based venous valves |
US7556646B2 (en) | 2001-09-13 | 2009-07-07 | Edwards Lifesciences Corporation | Methods and apparatuses for deploying minimally-invasive heart valves |
US6733525B2 (en) | 2001-03-23 | 2004-05-11 | Edwards Lifesciences Corporation | Rolled minimally-invasive heart valves and methods of use |
EP1245202B1 (en) | 2001-03-27 | 2004-08-04 | William Cook Europe ApS | An aortic graft device |
ATE397426T1 (de) | 2001-03-29 | 2008-06-15 | Viacor Inc | Gerät zur verbesserung der mitralklappenfunktion |
US6764505B1 (en) | 2001-04-12 | 2004-07-20 | Advanced Cardiovascular Systems, Inc. | Variable surface area stent |
WO2005074367A2 (en) | 2004-02-03 | 2005-08-18 | Atria Medical Inc. | Device and method for controlling in-vivo pressure |
WO2002087481A1 (en) | 2001-04-27 | 2002-11-07 | Myomend, Inc. | Prevention of myocardial infarction induced ventricular expansion and remodeling |
DE10121210B4 (de) | 2001-04-30 | 2005-11-17 | Universitätsklinikum Freiburg | Verankerungselement zur intraluminalen Verankerung eines Herzklappenersatzes und Verfahren zu seiner Herstellung |
EP1385455A1 (en) | 2001-05-01 | 2004-02-04 | Imperial Medical Devices Limited | Valve prosthesis |
EP1406608B1 (en) | 2001-05-02 | 2009-07-29 | Nitromed, Inc. | Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use |
US6800090B2 (en) | 2001-05-14 | 2004-10-05 | Cardiac Dimensions, Inc. | Mitral valve therapy device, system and method |
US6676702B2 (en) | 2001-05-14 | 2004-01-13 | Cardiac Dimensions, Inc. | Mitral valve therapy assembly and method |
US7935145B2 (en) | 2001-05-17 | 2011-05-03 | Edwards Lifesciences Corporation | Annuloplasty ring for ischemic mitral valve insuffuciency |
US6858039B2 (en) | 2002-07-08 | 2005-02-22 | Edwards Lifesciences Corporation | Mitral valve annuloplasty ring having a posterior bow |
ITMI20011012A1 (it) | 2001-05-17 | 2002-11-17 | Ottavio Alfieri | Protesi anulare per valvola mitrale |
US7087088B2 (en) | 2001-05-24 | 2006-08-08 | Torax Medical, Inc. | Methods and apparatus for regulating the flow of matter through body tubing |
CA2447998A1 (en) | 2001-05-24 | 2002-11-28 | Chase Medical, L.P. | Apparatus, kit, and method for use during ventricular restoration |
GB0113121D0 (en) | 2001-05-30 | 2001-07-18 | Univ Leeds | Biologically active photosensitisers |
US6926732B2 (en) | 2001-06-01 | 2005-08-09 | Ams Research Corporation | Stent delivery device and method |
CA2446596C (en) | 2001-06-08 | 2010-03-30 | Rex Medical, L.P. | Vascular device with valve for approximating vessel wall |
DE60106216T2 (de) | 2001-06-11 | 2005-11-17 | Sorin Biomedica Cardio S.P.A., Saluggia | Annuloplastieprothese und Herstellungsverfahren dafür |
US20030017775A1 (en) | 2001-06-11 | 2003-01-23 | Scimed Life Systems. Inc.. | Composite ePTFE/textile prosthesis |
NL1018302C1 (nl) | 2001-06-15 | 2002-07-17 | Eric Berreklouw | Applicator voor een prothese, samenstel omvattende een dergelijke applicator alsmede spanstelsel voor het laden van een dergelijke applicator. |
US8771302B2 (en) | 2001-06-29 | 2014-07-08 | Medtronic, Inc. | Method and apparatus for resecting and replacing an aortic valve |
US7544206B2 (en) | 2001-06-29 | 2009-06-09 | Medtronic, Inc. | Method and apparatus for resecting and replacing an aortic valve |
FR2826863B1 (fr) | 2001-07-04 | 2003-09-26 | Jacques Seguin | Ensemble permettant la mise en place d'une valve prothetique dans un conduit corporel |
US7547322B2 (en) | 2001-07-19 | 2009-06-16 | The Cleveland Clinic Foundation | Prosthetic valve and method for making same |
CA2455522C (en) | 2001-07-26 | 2009-12-08 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
FR2828091B1 (fr) | 2001-07-31 | 2003-11-21 | Seguin Jacques | Ensemble permettant la mise en place d'une valve prothetique dans un conduit corporel |
FR2828263B1 (fr) | 2001-08-03 | 2007-05-11 | Philipp Bonhoeffer | Dispositif d'implantation d'un implant et procede d'implantation du dispositif |
US20040249443A1 (en) | 2001-08-20 | 2004-12-09 | Shanley John F. | Expandable medical device for treating cardiac arrhythmias |
US6726716B2 (en) | 2001-08-24 | 2004-04-27 | Edwards Lifesciences Corporation | Self-molding annuloplasty ring |
US6845776B2 (en) | 2001-08-27 | 2005-01-25 | Richard S. Stack | Satiation devices and methods |
US6675809B2 (en) | 2001-08-27 | 2004-01-13 | Richard S. Stack | Satiation devices and methods |
US6908482B2 (en) | 2001-08-28 | 2005-06-21 | Edwards Lifesciences Corporation | Three-dimensional annuloplasty ring and template |
US6716158B2 (en) | 2001-09-07 | 2004-04-06 | Mardil, Inc. | Method and apparatus for external stabilization of the heart |
US6562069B2 (en) | 2001-09-19 | 2003-05-13 | St. Jude Medical, Inc. | Polymer leaflet designs for medical devices |
US6695769B2 (en) | 2001-09-25 | 2004-02-24 | The Foundry, Inc. | Passive ventricular support devices and methods of using them |
US7060023B2 (en) | 2001-09-25 | 2006-06-13 | The Foundry Inc. | Pericardium reinforcing devices and methods of using them |
EP1429690B1 (en) | 2001-09-26 | 2006-11-29 | Edwards Lifesciences Corporation | Low-profile heart valve sewing ring |
DE10148185B4 (de) | 2001-09-28 | 2005-08-11 | Alveolus, Inc. | Instrument zum Implantieren von Gefäßprothesen |
CA2981561C (en) | 2001-10-04 | 2020-08-25 | Neovasc Medical Ltd. | Flow reducing implant |
US6790237B2 (en) | 2001-10-09 | 2004-09-14 | Scimed Life Systems, Inc. | Medical stent with a valve and related methods of manufacturing |
US6893460B2 (en) | 2001-10-11 | 2005-05-17 | Percutaneous Valve Technologies Inc. | Implantable prosthetic valve |
US6893431B2 (en) | 2001-10-15 | 2005-05-17 | Scimed Life Systems, Inc. | Medical device for delivering patches |
US7192766B2 (en) | 2001-10-23 | 2007-03-20 | Medtronic Minimed, Inc. | Sensor containing molded solidified protein |
US6923936B2 (en) | 2001-10-23 | 2005-08-02 | Medtronic Minimed, Inc. | Sterile device and method for producing same |
GB0125925D0 (en) | 2001-10-29 | 2001-12-19 | Univ Glasgow | Mitral valve prosthesis |
JP2005517635A (ja) | 2001-11-07 | 2005-06-16 | フュアエスツェー アクチェンゲゼルシャフト | 選択的な抗菌剤 |
US6805710B2 (en) | 2001-11-13 | 2004-10-19 | Edwards Lifesciences Corporation | Mitral valve annuloplasty ring for molding left ventricle geometry |
US20050177180A1 (en) | 2001-11-28 | 2005-08-11 | Aptus Endosystems, Inc. | Devices, systems, and methods for supporting tissue and/or structures within a hollow body organ |
EP1465546B1 (en) | 2001-11-29 | 2007-07-18 | Cook Incorporated | Medical device delivery system |
US20030176914A1 (en) | 2003-01-21 | 2003-09-18 | Rabkin Dmitry J. | Multi-segment modular stent and methods for manufacturing stents |
US7294146B2 (en) | 2001-12-03 | 2007-11-13 | Xtent, Inc. | Apparatus and methods for delivery of variable length stents |
US6908478B2 (en) | 2001-12-05 | 2005-06-21 | Cardiac Dimensions, Inc. | Anchor and pull mitral valve device and method |
US20030105517A1 (en) | 2001-12-05 | 2003-06-05 | White Geoffrey Hamilton | Non-foreshortening stent |
US6976995B2 (en) | 2002-01-30 | 2005-12-20 | Cardiac Dimensions, Inc. | Fixed length anchor and pull mitral valve device and method |
US20080249504A1 (en) | 2007-04-06 | 2008-10-09 | Lattouf Omar M | Instrument port |
AU2002360765C1 (en) | 2001-12-20 | 2009-06-11 | Trivascular, Inc. | Advanced endovascular graft |
US6682537B2 (en) | 2001-12-20 | 2004-01-27 | The Cleveland Clinic Foundation | Apparatus and method for capturing a wire in a blood vessel |
US7014653B2 (en) | 2001-12-20 | 2006-03-21 | Cleveland Clinic Foundation | Furcated endovascular prosthesis |
US7147661B2 (en) | 2001-12-20 | 2006-12-12 | Boston Scientific Santa Rosa Corp. | Radially expandable stent |
US6641606B2 (en) | 2001-12-20 | 2003-11-04 | Cleveland Clinic Foundation | Delivery system and method for deploying an endovascular prosthesis |
EP1465555B1 (en) | 2001-12-21 | 2015-05-06 | QuickRing Medical Technologies Ltd. | Implantation system for annuloplasty rings |
US8123801B2 (en) | 2001-12-21 | 2012-02-28 | QuickRing Medical Technologies, Ltd. | Implantation system for annuloplasty rings |
US7201771B2 (en) | 2001-12-27 | 2007-04-10 | Arbor Surgical Technologies, Inc. | Bioprosthetic heart valve |
ATE462378T1 (de) | 2001-12-28 | 2010-04-15 | Edwards Lifesciences Ag | Speichervorrichtung mit verzögerung |
US7189258B2 (en) | 2002-01-02 | 2007-03-13 | Medtronic, Inc. | Heart valve system |
US7033390B2 (en) | 2002-01-02 | 2006-04-25 | Medtronic, Inc. | Prosthetic heart valve system |
US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
US8308797B2 (en) | 2002-01-04 | 2012-11-13 | Colibri Heart Valve, LLC | Percutaneously implantable replacement heart valve device and method of making same |
US20030130729A1 (en) | 2002-01-04 | 2003-07-10 | David Paniagua | Percutaneously implantable replacement heart valve device and method of making same |
JP2005515829A (ja) | 2002-01-28 | 2005-06-02 | オーバス メディカル テクノロジーズ インク. | フレア形の開口挿入人工器具および送出システム |
US6756449B2 (en) | 2002-02-27 | 2004-06-29 | Medtronic, Inc. | AnB block copolymers containing poly (vinyl pyrrolidone) units, medical devices, and methods |
US7048754B2 (en) | 2002-03-01 | 2006-05-23 | Evalve, Inc. | Suture fasteners and methods of use |
US6797001B2 (en) | 2002-03-11 | 2004-09-28 | Cardiac Dimensions, Inc. | Device, assembly and method for mitral valve repair |
ITPD20020064A1 (it) | 2002-03-12 | 2003-09-12 | Fidia Advanced Biopolymers Srl | Derivati esterei dell'acido ialuronico per la preparazione di idrogelda utilizzare in campo biomedico, sanitario e chirurgico e come sistem |
US6719786B2 (en) | 2002-03-18 | 2004-04-13 | Medtronic, Inc. | Flexible annuloplasty prosthesis and holder |
EP1348406B1 (en) | 2002-03-27 | 2009-12-09 | Sorin Biomedica Cardio S.R.L. | A prosthesis for annuloplasty comprising a perforated element |
NL1020288C1 (nl) | 2002-04-02 | 2003-05-07 | Eric Berreklouw | Samenstel omvattende een stabilisator en een in of rondom een door lichaamsweefsel, omgeven doorgang te positioneren instrument. |
US6752828B2 (en) | 2002-04-03 | 2004-06-22 | Scimed Life Systems, Inc. | Artificial valve |
CA2481488C (en) | 2002-04-09 | 2012-01-24 | Astra Tech Ab | Medical prosthetic device coated with a layer of corresponding metal hydroxide |
US7108685B2 (en) | 2002-04-15 | 2006-09-19 | Boston Scientific Scimed, Inc. | Patch stabilization of rods for treatment of cardiac muscle |
US7160320B2 (en) | 2002-04-16 | 2007-01-09 | The International Heart Institute Of Montana Foundation | Reed valve for implantation into mammalian blood vessels and heart with optional temporary or permanent support |
US8721713B2 (en) | 2002-04-23 | 2014-05-13 | Medtronic, Inc. | System for implanting a replacement valve |
US20030199971A1 (en) | 2002-04-23 | 2003-10-23 | Numed, Inc. | Biological replacement valve assembly |
FR2838631B1 (fr) | 2002-04-23 | 2004-12-24 | Engeneering And Technological | Procede de realisation d'une prothese de valve cardiaque aortique ou mitrale et prothese de valve cardiaque aortique ou mitrale ainsi obtenue |
US6761735B2 (en) | 2002-04-25 | 2004-07-13 | Medtronic, Inc. | Heart valve fixation process and apparatus |
US7331993B2 (en) | 2002-05-03 | 2008-02-19 | The General Hospital Corporation | Involuted endovascular valve and method of construction |
ES2318130T3 (es) | 2002-05-08 | 2009-05-01 | Cardiac Dimensions, Inc. | Dispositivo para modificar la forma de una valvula mitral. |
US7485141B2 (en) | 2002-05-10 | 2009-02-03 | Cordis Corporation | Method of placing a tubular membrane on a structural frame |
MXPA04011144A (es) | 2002-05-10 | 2005-08-16 | Johnson & Johnson | Metodos para hacer un dispositivo medico que tiene una membrana tubular de pared delgada sobre un armazon estructural. |
US7351256B2 (en) | 2002-05-10 | 2008-04-01 | Cordis Corporation | Frame based unidirectional flow prosthetic implant |
DE10221076A1 (de) | 2002-05-11 | 2003-11-27 | Ruesch Willy Gmbh | Stent |
US20030220683A1 (en) | 2002-05-22 | 2003-11-27 | Zarouhi Minasian | Endoluminal device having barb assembly and method of using same |
CN100341589C (zh) | 2002-05-24 | 2007-10-10 | 血管技术国际股份公司 | 用于涂覆医用植入物的组合物和方法 |
US6986775B2 (en) | 2002-06-13 | 2006-01-17 | Guided Delivery Systems, Inc. | Devices and methods for heart valve repair |
US20060122633A1 (en) | 2002-06-13 | 2006-06-08 | John To | Methods and devices for termination |
US9226825B2 (en) | 2002-06-13 | 2016-01-05 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
WO2004000138A1 (en) | 2002-06-19 | 2003-12-31 | Tyco Healthcare Group Lp | Method and apparatus for anastomosis |
US7044962B2 (en) | 2002-06-25 | 2006-05-16 | Scimed Life Systems, Inc. | Implantable prosthesis with displaceable skirt |
US7959674B2 (en) | 2002-07-16 | 2011-06-14 | Medtronic, Inc. | Suture locking assembly and method of use |
US7172625B2 (en) | 2002-07-16 | 2007-02-06 | Medtronic, Inc. | Suturing rings for implantable heart valve prostheses |
US7578843B2 (en) | 2002-07-16 | 2009-08-25 | Medtronic, Inc. | Heart valve prosthesis |
CA2487405A1 (en) | 2002-07-26 | 2004-02-05 | Emphasys Medical, Inc. | Bronchial flow control devices with membrane seal |
DE10235237A1 (de) | 2002-08-01 | 2004-02-12 | Symetis Ag | In-vitro-Verfahren zum Herstellen einer homologen "gestenteten" Tissue eingineerten Herzklappe |
US8292884B2 (en) | 2002-08-01 | 2012-10-23 | Levine Robert A | Cardiac devices and methods for minimally invasive repair of ischemic mitral regurgitation |
AU2003219503A1 (en) | 2002-08-08 | 2004-02-25 | Neovasc Medical Ltd. | Geometric flow regulator |
WO2004014474A1 (en) | 2002-08-08 | 2004-02-19 | Neovasc Medical Ltd. | Flow reducing implant |
DE10301026B4 (de) | 2002-08-13 | 2014-10-30 | Jenavalve Technology Inc. | Vorrichtung zur Verankerung und Ausrichtung von Herzklappenprothesen |
DE20321838U1 (de) | 2002-08-13 | 2011-02-10 | JenaValve Technology Inc., Wilmington | Vorrichtung zur Verankerung und Ausrichtung von Herzklappenprothesen |
AU2003265477B2 (en) | 2002-08-15 | 2009-08-13 | Cook Medical Technologies Llc | Stent and method of forming a stent with integral barbs |
WO2004016200A1 (en) | 2002-08-15 | 2004-02-26 | Cook Incorporated | Implantable vascular device |
CA2827984A1 (en) | 2002-08-28 | 2004-03-11 | Heart Leaflet Technologies, Inc. | Method and device for treating diseased valve |
WO2004019826A1 (en) | 2002-08-29 | 2004-03-11 | Md3 Technologies, Llc | Apparatus for implanting surgical devices |
KR100442330B1 (ko) | 2002-09-03 | 2004-07-30 | 주식회사 엠아이텍 | 스텐트 및 이 스텐트의 제조방법 |
DE10242154A1 (de) | 2002-09-05 | 2004-03-18 | Sievers, Hans-Heinrich, Prof.Dr. | Gefäßprothese, insbesondere zum Ersatz der Aorta ascendens |
US6875231B2 (en) | 2002-09-11 | 2005-04-05 | 3F Therapeutics, Inc. | Percutaneously deliverable heart valve |
US7137184B2 (en) | 2002-09-20 | 2006-11-21 | Edwards Lifesciences Corporation | Continuous heart valve support frame and method of manufacture |
CO5500017A1 (es) | 2002-09-23 | 2005-03-31 | 3F Therapeutics Inc | Valvula mitral protesica |
CA2498030A1 (en) | 2002-10-01 | 2004-04-15 | Ample Medical, Inc. | Devices, systems, and methods for reshaping a heart valve annulus |
AU2003282617B2 (en) | 2002-10-10 | 2006-06-29 | The Cleveland Clinic Foundation | Method and apparatus for replacing a mitral valve with a stentless bioprosthetic valve having chordae |
US8070743B2 (en) | 2002-11-01 | 2011-12-06 | Valentx, Inc. | Devices and methods for attaching an endolumenal gastrointestinal implant |
US6814746B2 (en) | 2002-11-01 | 2004-11-09 | Ev3 Peripheral, Inc. | Implant delivery system with marker interlock |
EP1862128B1 (en) | 2002-11-12 | 2011-07-20 | Edwards Lifesciences AG | Devices for heart valve treatment |
AU2003294293A1 (en) | 2002-11-13 | 2004-06-03 | Viacor, Inc. | Cardiac valve procedure methods and devices |
US7485143B2 (en) | 2002-11-15 | 2009-02-03 | Abbott Cardiovascular Systems Inc. | Apparatuses and methods for heart valve repair |
DE60328918D1 (de) | 2002-11-27 | 2009-10-01 | Carag Ag | Implantat zum verschliessen einer körperöffnung |
FR2847800B1 (fr) | 2002-11-28 | 2005-10-14 | Perouse Laboratoires | Valve prothetique interchangeable |
US7608114B2 (en) | 2002-12-02 | 2009-10-27 | Gi Dynamics, Inc. | Bariatric sleeve |
GB0229274D0 (en) | 2002-12-16 | 2003-01-22 | Anson Medical Ltd | Instrument for testing pulsatile endurance of vascular implants |
US8551162B2 (en) | 2002-12-20 | 2013-10-08 | Medtronic, Inc. | Biologically implantable prosthesis |
US8088158B2 (en) | 2002-12-20 | 2012-01-03 | Boston Scientific Scimed, Inc. | Radiopaque ePTFE medical devices |
US6945957B2 (en) | 2002-12-30 | 2005-09-20 | Scimed Life Systems, Inc. | Valve treatment catheter and methods |
EP1594569B1 (en) | 2003-01-27 | 2014-05-14 | Corassist Cardiovascular Ltd. | In vivo device for improving diastolic ventricular function |
US7767219B2 (en) | 2003-01-31 | 2010-08-03 | Boston Scientific Scimed, Inc. | Localized drug delivery using drug-loaded nanocapsules |
GB2398245B (en) | 2003-02-06 | 2007-03-28 | Great Ormond Street Hospital F | Valve prosthesis |
PT1444993E (pt) | 2003-02-10 | 2007-01-31 | Heraeus Gmbh W C | Liga metálica melhorada para dispositivos médicos e implantes |
US7077801B2 (en) | 2003-02-19 | 2006-07-18 | Corlife Gbr | Methods and devices for improving cardiac output |
US20040254600A1 (en) | 2003-02-26 | 2004-12-16 | David Zarbatany | Methods and devices for endovascular mitral valve correction from the left coronary sinus |
WO2004078073A1 (en) | 2003-02-28 | 2004-09-16 | Edward G Shifrin | Extravenous corrector for repair of incompetent venous valves |
US20040220655A1 (en) | 2003-03-03 | 2004-11-04 | Sinus Rhythm Technologies, Inc. | Electrical conduction block implant device |
US7402171B2 (en) | 2003-03-12 | 2008-07-22 | Cook Incorporated | Prosthetic valve that permits retrograde flow |
US7381210B2 (en) | 2003-03-14 | 2008-06-03 | Edwards Lifesciences Corporation | Mitral valve repair system and method for use |
WO2004082528A2 (en) | 2003-03-17 | 2004-09-30 | Cook Incorporated | Vascular valve with removable support component |
US7399315B2 (en) | 2003-03-18 | 2008-07-15 | Edwards Lifescience Corporation | Minimally-invasive heart valve with cusp positioners |
US8088404B2 (en) | 2003-03-20 | 2012-01-03 | Medtronic Vasular, Inc. | Biocompatible controlled release coatings for medical devices and related methods |
ES2311148T3 (es) | 2003-03-20 | 2009-02-01 | Aortech International Plc | Valvula. |
CH696185A5 (fr) | 2003-03-21 | 2007-02-15 | Afksendiyos Kalangos | Dispositif de renfort intraparietal pour prothèse biologique et prothèse biologique renforcée. |
US7771463B2 (en) | 2003-03-26 | 2010-08-10 | Ton Dai T | Twist-down implant delivery technologies |
KR100466839B1 (ko) | 2003-03-28 | 2005-01-17 | 주식회사 사이언씨티 | 대동맥판막 성형기구 세트 및 이를 이용한 치료방법 |
US8118732B2 (en) | 2003-04-01 | 2012-02-21 | Boston Scientific Scimed, Inc. | Force feedback control system for video endoscope |
WO2004089253A1 (en) | 2003-04-01 | 2004-10-21 | Cook Incorporated | Percutaneously deployed vascular valves |
DE602004024972D1 (de) | 2003-04-08 | 2010-02-25 | Cook Inc | Intraluminale stützvorrichtung mit graft |
US7530995B2 (en) | 2003-04-17 | 2009-05-12 | 3F Therapeutics, Inc. | Device for reduction of pressure effects of cardiac tricuspid valve regurgitation |
US7159593B2 (en) | 2003-04-17 | 2007-01-09 | 3F Therapeutics, Inc. | Methods for reduction of pressure effects of cardiac tricuspid valve regurgitation |
US7175656B2 (en) | 2003-04-18 | 2007-02-13 | Alexander Khairkhahan | Percutaneous transcatheter heart valve replacement |
WO2004096100A1 (en) | 2003-04-24 | 2004-11-11 | Cook Incorporated | Artificial valve prosthesis with improved flow dynamics |
GB0309616D0 (en) | 2003-04-28 | 2003-06-04 | Angiomed Gmbh & Co | Loading and delivery of self-expanding stents |
EP2335648A1 (en) | 2003-04-28 | 2011-06-22 | Kips Bay Medical, Inc. | Compliant venous graft |
EP1472995B1 (en) | 2003-04-30 | 2008-12-03 | Medtronic Vascular, Inc. | Perivascular leak repair system |
EP1472996B1 (en) | 2003-04-30 | 2009-09-30 | Medtronic Vascular, Inc. | Percutaneously delivered temporary valve |
US8791171B2 (en) | 2003-05-01 | 2014-07-29 | Abbott Cardiovascular Systems Inc. | Biodegradable coatings for implantable medical devices |
US8043854B2 (en) | 2003-05-15 | 2011-10-25 | Waseda University | Method of decellularizing tissues |
DE10322024A1 (de) | 2003-05-16 | 2004-12-02 | Symetis Ag | Bioreaktor zum Herstellen einer Gewebeprothese, insbesondere Herzklappe |
EP2191790A3 (en) | 2003-05-19 | 2012-10-17 | SeptRx, Inc. | Tissue distention device and related methods for therapeutic intervention |
US7128759B2 (en) | 2003-05-19 | 2006-10-31 | Cook Incorporated | Implantable medical device with constrained expansion |
ATE465694T1 (de) | 2003-05-20 | 2010-05-15 | Cleveland Clinic Foundation | Vorrichtung zur reparatur von herzklappen |
US7520947B2 (en) | 2003-05-23 | 2009-04-21 | Ati Properties, Inc. | Cobalt alloys, methods of making cobalt alloys, and implants and articles of manufacture made therefrom |
WO2004105651A1 (en) | 2003-05-28 | 2004-12-09 | Cook Incorporated | Prosthetic valve with vessel engaging member |
US7445593B2 (en) | 2003-06-18 | 2008-11-04 | The Texas A&M University System | Device for proactive modulation of cardiac strain patterns |
US6974862B2 (en) | 2003-06-20 | 2005-12-13 | Kensey Nash Corporation | High density fibrous polymers suitable for implant |
US7201772B2 (en) | 2003-07-08 | 2007-04-10 | Ventor Technologies, Ltd. | Fluid flow prosthetic device |
CA2531528C (en) | 2003-07-08 | 2013-09-03 | Ventor Technologies Ltd. | Implantable prosthetic devices particularly for transarterial delivery in the treatment of aortic stenosis, and methods of implanting such devices |
NZ527025A (en) | 2003-07-16 | 2007-01-26 | David Peter Shaw | Prosthetic valves for medical application |
IES20030531A2 (en) | 2003-07-17 | 2005-09-21 | Medtronic Vascular Connaught | Methods and devices for placing a fistula device in fluid communication with a target vessel |
WO2005018507A2 (en) | 2003-07-18 | 2005-03-03 | Ev3 Santa Rosa, Inc. | Remotely activated mitral annuloplasty system and methods |
DE602004023095D1 (de) | 2003-07-21 | 2009-10-22 | Univ Pennsylvania | Perkutane herzklappe |
US9498366B2 (en) | 2003-07-28 | 2016-11-22 | Baronova, Inc. | Devices and methods for pyloric anchoring |
DE10334868B4 (de) | 2003-07-29 | 2013-10-17 | Pfm Medical Ag | Implantierbare Einrichtung als Organklappenersatz, dessen Herstellungsverfahren sowie Grundkörper und Membranelement dafür |
US7153324B2 (en) | 2003-07-31 | 2006-12-26 | Cook Incorporated | Prosthetic valve devices and methods of making such devices |
FR2858543B1 (fr) | 2003-08-08 | 2006-02-03 | Assist Publ Hopitaux De Paris | Anneau aortique et ancillaire pour sa pose |
RU2360646C2 (ru) | 2003-08-14 | 2009-07-10 | Блу Медикел Дивайсиз Б.В. | Эндолюминальный протез, содержащий лечебное средство |
US7735493B2 (en) | 2003-08-15 | 2010-06-15 | Atritech, Inc. | System and method for delivering a left atrial appendage containment device |
US8021421B2 (en) | 2003-08-22 | 2011-09-20 | Medtronic, Inc. | Prosthesis heart valve fixturing device |
DE10340265A1 (de) | 2003-08-29 | 2005-04-07 | Sievers, Hans-Hinrich, Prof. Dr.med. | Prothese zum Ersatz der Aorten- und/oder Mitralklappe des Herzens |
DE10342757A1 (de) | 2003-09-16 | 2005-04-07 | Campus Gmbh & Co. Kg | Stent mit endständigen Verankerungselemeneten |
US7785653B2 (en) | 2003-09-22 | 2010-08-31 | Innovational Holdings Llc | Method and apparatus for loading a beneficial agent into an expandable medical device |
US20050075725A1 (en) | 2003-10-02 | 2005-04-07 | Rowe Stanton J. | Implantable prosthetic valve with non-laminar flow |
AU2004279391A1 (en) | 2003-10-03 | 2005-04-21 | Edwards Lifesciences Corporation | Annuloplasty rings for repair of abnormal mitral valves |
US7842084B2 (en) | 2005-06-21 | 2010-11-30 | 3F Therapeutics, Inc. | Method and systems for sizing, folding, holding, and delivering a heart valve prosthesis |
US20050075712A1 (en) | 2003-10-06 | 2005-04-07 | Brian Biancucci | Minimally invasive valve replacement system |
US9579194B2 (en) | 2003-10-06 | 2017-02-28 | Medtronic ATS Medical, Inc. | Anchoring structure with concave landing zone |
US10219899B2 (en) | 2004-04-23 | 2019-03-05 | Medtronic 3F Therapeutics, Inc. | Cardiac valve replacement systems |
US20060259137A1 (en) | 2003-10-06 | 2006-11-16 | Jason Artof | Minimally invasive valve replacement system |
WO2005046528A1 (en) | 2003-10-06 | 2005-05-26 | 3F Therapeutics, Inc. | Minimally invasive valve replacement system |
US7604650B2 (en) | 2003-10-06 | 2009-10-20 | 3F Therapeutics, Inc. | Method and assembly for distal embolic protection |
US7556647B2 (en) | 2003-10-08 | 2009-07-07 | Arbor Surgical Technologies, Inc. | Attachment device and methods of using the same |
US7425219B2 (en) | 2003-10-10 | 2008-09-16 | Arshad Quadri | System and method for endoluminal grafting of bifurcated and branched vessels |
EP1684656B1 (en) | 2003-10-17 | 2016-12-07 | Edwards Lifesciences AG | Heart valve leaflet locator |
US7635382B2 (en) | 2003-10-22 | 2009-12-22 | Medtronic Vascular, Inc. | Delivery system for long self-expanding stents |
ITBO20030631A1 (it) | 2003-10-23 | 2005-04-24 | Roberto Erminio Parravicini | Apparecchiatura protesica valvolare, in particolare per applicazioni cardiache. |
US7347869B2 (en) | 2003-10-31 | 2008-03-25 | Cordis Corporation | Implantable valvular prosthesis |
US7070616B2 (en) | 2003-10-31 | 2006-07-04 | Cordis Corporation | Implantable valvular prosthesis |
BRPI0416161A (pt) | 2003-11-03 | 2007-01-23 | Balloon Ltd B | tratamento de bifurcação vasculares |
SE526861C2 (sv) | 2003-11-17 | 2005-11-15 | Syntach Ag | Vävnadslesionsskapande anordning samt en uppsättning av anordningar för behandling av störningar i hjärtrytmregleringssystemet |
US7740656B2 (en) | 2003-11-17 | 2010-06-22 | Medtronic, Inc. | Implantable heart valve prosthetic devices having intrinsically conductive polymers |
WO2005056073A2 (en) | 2003-12-03 | 2005-06-23 | Mayo Foundation For Medical Education And Research | Kits, apparatus and methods for magnetically coating medical devices with living cells |
WO2006126979A2 (en) | 2003-12-04 | 2006-11-30 | Ev3, Inc. | System and method for delivering a left atrial appendage containment device |
WO2005060882A1 (en) | 2003-12-09 | 2005-07-07 | Gi Dynamics, Inc. | Apparatus to be anchored within the gastrointestinal tract and anchoring method |
US7186265B2 (en) | 2003-12-10 | 2007-03-06 | Medtronic, Inc. | Prosthetic cardiac valves and systems and methods for implanting thereof |
US8128681B2 (en) | 2003-12-19 | 2012-03-06 | Boston Scientific Scimed, Inc. | Venous valve apparatus, system, and method |
WO2005058210A1 (en) | 2003-12-19 | 2005-06-30 | Patrick Leahy | An anti-reflux system |
WO2005062837A2 (en) | 2003-12-19 | 2005-07-14 | Cardiac Dimensions, Inc. | Device for modifying the shape of a body organ |
US7261732B2 (en) | 2003-12-22 | 2007-08-28 | Henri Justino | Stent mounted valve |
EP2926767B2 (en) | 2003-12-23 | 2023-03-08 | Boston Scientific Scimed, Inc. | Repositionable heart valve |
US9005273B2 (en) | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
US7959666B2 (en) | 2003-12-23 | 2011-06-14 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US8182528B2 (en) | 2003-12-23 | 2012-05-22 | Sadra Medical, Inc. | Locking heart valve anchor |
US7381219B2 (en) | 2003-12-23 | 2008-06-03 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
US7445631B2 (en) | 2003-12-23 | 2008-11-04 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20120041550A1 (en) | 2003-12-23 | 2012-02-16 | Sadra Medical, Inc. | Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements |
AU2003299404A1 (en) | 2003-12-23 | 2005-08-11 | Laboratoires Perouse | Kit which is intended to be implanted in a conduit |
US7748389B2 (en) | 2003-12-23 | 2010-07-06 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US7329279B2 (en) | 2003-12-23 | 2008-02-12 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20050137687A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Heart valve anchor and method |
US20050137696A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Apparatus and methods for protecting against embolization during endovascular heart valve replacement |
US20050137694A1 (en) | 2003-12-23 | 2005-06-23 | Haug Ulrich R. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20050137691A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Two piece heart valve and anchor |
US8603160B2 (en) | 2003-12-23 | 2013-12-10 | Sadra Medical, Inc. | Method of using a retrievable heart valve anchor with a sheath |
US8828078B2 (en) | 2003-12-23 | 2014-09-09 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US7780725B2 (en) | 2004-06-16 | 2010-08-24 | Sadra Medical, Inc. | Everting heart valve |
US8287584B2 (en) | 2005-11-14 | 2012-10-16 | Sadra Medical, Inc. | Medical implant deployment tool |
US20050137686A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Externally expandable heart valve anchor and method |
US7824443B2 (en) | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Medical implant delivery and deployment tool |
DK2926766T3 (en) | 2003-12-23 | 2016-05-17 | Boston Scient Scimed Inc | REPONIBLE HEART VALVE |
EP2529699B1 (en) | 2003-12-23 | 2014-01-29 | Sadra Medical, Inc. | Repositionable heart valve |
US9526609B2 (en) | 2003-12-23 | 2016-12-27 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
EP1557138B1 (de) | 2004-01-21 | 2012-12-05 | Admedes Schuessler GmbH | Expandierbarer Stent mit Koppeleinrichtung |
US7871435B2 (en) | 2004-01-23 | 2011-01-18 | Edwards Lifesciences Corporation | Anatomically approximate prosthetic mitral heart valve |
US7597711B2 (en) | 2004-01-26 | 2009-10-06 | Arbor Surgical Technologies, Inc. | Heart valve assembly with slidable coupling connections |
CA2556077C (en) | 2004-02-05 | 2012-05-01 | Children's Medical Center Corporation | Transcatheter delivery of a replacement heart valve |
DE602004023812D1 (de) | 2004-02-06 | 2009-12-10 | Sangomed S R L | Externes Abstützelement zur Wiederherstellung der Funktionsfähigkeit von Venenklappen durch Zug an ihren Kommissurenwänden |
FR2865926B1 (fr) | 2004-02-11 | 2006-05-12 | Perouse Laboratoires | Prothese tubulaire. |
US7311730B2 (en) | 2004-02-13 | 2007-12-25 | Shlomo Gabbay | Support apparatus and heart valve prosthesis for sutureless implantation |
EP1727499B1 (en) | 2004-02-20 | 2012-06-13 | Cook Medical Technologies LLC | Prosthetic valve with spacing member |
US8206439B2 (en) | 2004-02-23 | 2012-06-26 | International Heart Institute Of Montana Foundation | Internal prosthesis for reconstruction of cardiac geometry |
US20090132035A1 (en) | 2004-02-27 | 2009-05-21 | Roth Alex T | Prosthetic Heart Valves, Support Structures and Systems and Methods for Implanting the Same |
ITTO20040135A1 (it) | 2004-03-03 | 2004-06-03 | Sorin Biomedica Cardio Spa | Protesi valvolare cardiaca |
EP1722716B1 (en) | 2004-03-08 | 2017-08-16 | Pulmonx, Inc | Implanted bronchial isolation devices and methods |
EP1734903B2 (en) | 2004-03-11 | 2022-01-19 | Percutaneous Cardiovascular Solutions Pty Limited | Percutaneous heart valve prosthesis |
US8777974B2 (en) | 2004-03-19 | 2014-07-15 | Aga Medical Corporation | Multi-layer braided structures for occluding vascular defects |
NL1025830C2 (nl) | 2004-03-26 | 2005-02-22 | Eric Berreklouw | Samenstel omvattende een ring voor bevestiging in een door lichaamsweefsel omgeven doorgang alsmede een applicator voor het in de doorgang plaatsen van de ring. |
US20050228494A1 (en) | 2004-03-29 | 2005-10-13 | Salvador Marquez | Controlled separation heart valve frame |
CA2561667C (en) | 2004-03-30 | 2010-04-06 | Toyo Advanced Technologies Co., Ltd. | Method for treating surface of material, surface-treated material, medical material, and medical instrument |
AU2005231356A1 (en) | 2004-03-31 | 2005-10-20 | Med Institute, Inc. | Endoluminal graft with a prosthetic valve |
US7993397B2 (en) | 2004-04-05 | 2011-08-09 | Edwards Lifesciences Ag | Remotely adjustable coronary sinus implant |
US8349001B2 (en) | 2004-04-07 | 2013-01-08 | Medtronic, Inc. | Pharmacological delivery implement for use with cardiac repair devices |
WO2005099627A1 (en) | 2004-04-12 | 2005-10-27 | Cook Incorporated | Stent graft repair device |
NL1026076C2 (nl) | 2004-04-29 | 2005-11-01 | Univ Eindhoven Tech | Vormdeel vervaardigd door middel van elektro-spinnen en een werkwijze voor de vervaardiging daarvan evenals de toepassing van een dergelijk vormdeel. |
US7294148B2 (en) | 2004-04-29 | 2007-11-13 | Edwards Lifesciences Corporation | Annuloplasty ring for mitral valve prolapse |
EP1740265B1 (en) | 2004-04-30 | 2019-10-16 | St. Jude Medical, Cardiology Division, Inc. | Devices for modulation of heart valve function |
JP5227588B2 (ja) | 2004-05-05 | 2013-07-03 | ダイレクト フロウ メディカル、 インク. | 現場形成支持構造を備えたステントレス心臓弁 |
US20060095115A1 (en) | 2004-05-10 | 2006-05-04 | Youssef Bladillah | Stent and method of manufacturing same |
EP3398522B1 (en) | 2004-05-14 | 2019-12-25 | Evalve, Inc. | Locking mechanisms for fixation devices |
US8052748B2 (en) | 2004-05-14 | 2011-11-08 | St. Jude Medical, Inc. | Systems and methods for holding annuloplasty rings |
US7803182B2 (en) | 2004-05-28 | 2010-09-28 | Cordis Corporation | Biodegradable vascular device with buffering agent |
US7785615B2 (en) | 2004-05-28 | 2010-08-31 | Cordis Corporation | Biodegradable medical implant with encapsulated buffering agent |
WO2005120380A1 (en) | 2004-06-07 | 2005-12-22 | Image-Guided Neurologics, Inc. | Fiducial marker and protective cap |
WO2006007401A2 (en) | 2004-06-16 | 2006-01-19 | Machine Solutions, Inc. | Tissue prothesis processing technology |
EP1629795B1 (de) | 2004-06-29 | 2008-01-16 | SIEVERS, Hans-Hinrich, Dr. | Ringprothese für Anuloplastie |
US7462191B2 (en) | 2004-06-30 | 2008-12-09 | Edwards Lifesciences Pvt, Inc. | Device and method for assisting in the implantation of a prosthetic valve |
US7276078B2 (en) | 2004-06-30 | 2007-10-02 | Edwards Lifesciences Pvt | Paravalvular leak detection, sealing, and prevention |
US7167746B2 (en) | 2004-07-12 | 2007-01-23 | Ats Medical, Inc. | Anti-coagulation and demineralization system for conductive medical devices |
EP1768601A4 (en) | 2004-07-15 | 2007-08-15 | Micardia Corp | MAGNETIC DEVICES AND METHOD FOR CIRCULATING THE HEART ANATOMY |
US7389874B2 (en) | 2004-07-19 | 2008-06-24 | St. Jude Medical, Inc. | Heart valve support and storing lid system and methods associated therewith |
US20140107761A1 (en) | 2004-07-26 | 2014-04-17 | Abbott Cardiovascular Systems Inc. | Biodegradable stent with enhanced fracture toughness |
US7585369B2 (en) | 2004-08-04 | 2009-09-08 | Larson Marian L | Apparatus for coating medical devices |
EP1796693A2 (en) | 2004-08-26 | 2007-06-20 | Chandrashekhar P. Pathak | Implantable tissue compositions and method |
CA2578259A1 (en) | 2004-08-27 | 2006-03-09 | Cook Incorporated | Placement of multiple intraluminal medical devices within a body vessel |
CA2578706A1 (en) | 2004-09-01 | 2006-03-16 | Cook Incorporated | Delivery system which facilitates hydration of an intraluminal medical device |
US7566343B2 (en) | 2004-09-02 | 2009-07-28 | Boston Scientific Scimed, Inc. | Cardiac valve, system, and method |
FR2874813B1 (fr) | 2004-09-07 | 2007-06-22 | Perouse Soc Par Actions Simpli | Prothese valvulaire |
FR2874812B1 (fr) | 2004-09-07 | 2007-06-15 | Perouse Soc Par Actions Simpli | Valve protheique interchangeable |
US20060052867A1 (en) | 2004-09-07 | 2006-03-09 | Medtronic, Inc | Replacement prosthetic heart valve, system and method of implant |
US8961583B2 (en) | 2004-09-08 | 2015-02-24 | Cordis Corporation | Optimized flex link for expandable stent |
US20060135962A1 (en) | 2004-09-09 | 2006-06-22 | Kick George F | Expandable trans-septal sheath |
EP1796597B1 (en) | 2004-09-14 | 2013-01-09 | Edwards Lifesciences AG | Device for treatment of heart valve regurgitation |
AU2005287010B2 (en) | 2004-09-17 | 2010-04-15 | Gi Dynamics, Inc. | Gastrointestinal anchor |
EP1793745B2 (en) | 2004-09-27 | 2022-03-16 | Evalve, Inc. | Devices for tissue grasping and assessment |
CA3050938C (en) | 2004-10-02 | 2021-10-19 | Edwards Lifesciences Cardiaq Llc | Methods and devices for repair or replacement of heart valves or adjacent tissue without the need for full cardiopulmonary support |
DE602005009974D1 (de) | 2004-10-13 | 2008-11-06 | Medtronic Inc | Eichung von biologischen oder pharmazeutischen substanzen |
US20060079736A1 (en) | 2004-10-13 | 2006-04-13 | Sing-Fatt Chin | Method and device for percutaneous left ventricular reconstruction |
EP2319492A3 (en) | 2004-10-21 | 2011-08-10 | Genentech, Inc. | Method for treating intraocular neovascular diseases |
US7563276B2 (en) | 2004-10-29 | 2009-07-21 | Cook Incorporated | Intraluminal medical device with cannula for controlled retrograde flow |
DE102004054275A1 (de) | 2004-11-09 | 2006-05-11 | Bühler AG | Vorrichtung zum Trennen von körnigem Gut |
US7771472B2 (en) | 2004-11-19 | 2010-08-10 | Pulmonx Corporation | Bronchial flow control devices and methods of use |
US8562672B2 (en) | 2004-11-19 | 2013-10-22 | Medtronic, Inc. | Apparatus for treatment of cardiac valves and method of its manufacture |
DE602005026573D1 (de) | 2004-12-01 | 2011-04-07 | Cook Inc | Messfähiges abgabesystem für intraluminale medizinprodukte |
US20060122634A1 (en) | 2004-12-03 | 2006-06-08 | Ino Takashi H | Apparatus and method for delivering fasteners during valve replacement |
US7758640B2 (en) | 2004-12-16 | 2010-07-20 | Valvexchange Inc. | Cardiovascular valve assembly |
US7674238B2 (en) | 2004-12-23 | 2010-03-09 | Boston Scientific Scimed, Inc. | Methods and apparatus for emboli removal |
AU2005318938B2 (en) | 2004-12-24 | 2011-04-21 | Anteris Aus Operations Pty Ltd | An implantable biomaterial and a method of producing same |
US8287583B2 (en) | 2005-01-10 | 2012-10-16 | Taheri Laduca Llc | Apparatus and method for deploying an implantable device within the body |
DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
US8155754B2 (en) | 2005-01-25 | 2012-04-10 | Medtronic, Inc. | Method for fabrication of low-polarization implantable stimulation electrode |
US8731658B2 (en) | 2005-01-31 | 2014-05-20 | Physio-Control, Inc | System and method for using diagnostic pulses in connection with defibrillation therapy |
US20060173490A1 (en) | 2005-02-01 | 2006-08-03 | Boston Scientific Scimed, Inc. | Filter system and method |
EP2410948B1 (en) | 2005-02-07 | 2016-07-20 | Abbott Vascular | Devices for cardiac valve repair |
AU2006212750B2 (en) | 2005-02-07 | 2011-11-17 | Evalve, Inc. | Methods, systems and devices for cardiac valve repair |
US7670368B2 (en) | 2005-02-07 | 2010-03-02 | Boston Scientific Scimed, Inc. | Venous valve apparatus, system, and method |
US20080243233A1 (en) | 2005-02-08 | 2008-10-02 | B-Balloon Ltd. | Device and Methods for Treatment of Vascular Bifurcations |
ITTO20050074A1 (it) | 2005-02-10 | 2006-08-11 | Sorin Biomedica Cardio Srl | Protesi valvola cardiaca |
EP1693025A1 (en) | 2005-02-17 | 2006-08-23 | Universität Zürich | Method of manufacturing a tissue-engineered prosthesis |
DK1850796T3 (en) | 2005-02-18 | 2016-01-18 | Cleveland Clinic Foundation | DEVICE FOR REPLACEMENT OF A HEART VALVE |
US8057538B2 (en) | 2005-02-18 | 2011-11-15 | Medtronic, Inc. | Valve holder |
US7867274B2 (en) | 2005-02-23 | 2011-01-11 | Boston Scientific Scimed, Inc. | Valve apparatus, system and method |
US8025694B2 (en) | 2005-02-25 | 2011-09-27 | Abbott Laboratories Vascular Enterprises Limited | Modular vascular prosthesis and methods of use |
US7955385B2 (en) | 2005-02-28 | 2011-06-07 | Medtronic Vascular, Inc. | Device, system, and method for aiding valve annuloplasty |
US8083793B2 (en) | 2005-02-28 | 2011-12-27 | Medtronic, Inc. | Two piece heart valves including multiple lobe valves and methods for implanting them |
CN102247225B (zh) | 2005-02-28 | 2015-07-22 | 梅德坦提亚国际有限公司 | 用于改善心脏瓣膜功能的装置和成套工具 |
US7717955B2 (en) | 2005-02-28 | 2010-05-18 | Medtronic, Inc. | Conformable prosthesis for implanting two-piece heart valves and methods for using them |
US9248015B2 (en) | 2005-03-11 | 2016-02-02 | Wake Forest University Health Services | Production of tissue engineered heart valves |
FR2882916B1 (fr) | 2005-03-14 | 2007-06-15 | Assist Publ Hopitaux De Paris | Dispositif de mesure du diametre d'un panneau aortique |
WO2006097931A2 (en) | 2005-03-17 | 2006-09-21 | Valtech Cardio, Ltd. | Mitral valve treatment techniques |
US8454678B2 (en) | 2005-03-19 | 2013-06-04 | Cook Biotech Incorporated | Prosthetic implants including ECM composite material |
KR100691503B1 (ko) | 2005-03-21 | 2007-03-09 | (주) 태웅메디칼 | 식도용 스텐트 |
JP5271697B2 (ja) | 2005-03-23 | 2013-08-21 | アボット ラボラトリーズ | 医療装置を介する高親油性薬剤の送達 |
US7842085B2 (en) | 2005-03-23 | 2010-11-30 | Vaso Adzich | Annuloplasty ring and holder combination |
US7575595B2 (en) | 2005-03-23 | 2009-08-18 | Edwards Lifesciences Corporation | Annuloplasty ring and holder combination |
WO2006102546A1 (en) | 2005-03-24 | 2006-09-28 | Cook Incorporated | Exchangeable delivery system with distal protection |
EP2767260B1 (en) | 2005-03-25 | 2019-07-03 | St. Jude Medical, Cardiology Division, Inc. | Apparatus for controlling the internal circumference of an anatomic orifice or lumen |
US20060224232A1 (en) | 2005-04-01 | 2006-10-05 | Trivascular, Inc. | Hybrid modular endovascular graft |
FR2883721B1 (fr) | 2005-04-05 | 2007-06-22 | Perouse Soc Par Actions Simpli | Necessaire destine a etre implante dans un conduit de circulation du sang, et endoprothese tubulaire associee |
US8062359B2 (en) | 2005-04-06 | 2011-11-22 | Edwards Lifesciences Corporation | Highly flexible heart valve connecting band |
US7513909B2 (en) | 2005-04-08 | 2009-04-07 | Arbor Surgical Technologies, Inc. | Two-piece prosthetic valves with snap-in connection and methods for use |
US7722666B2 (en) | 2005-04-15 | 2010-05-25 | Boston Scientific Scimed, Inc. | Valve apparatus, system and method |
US20060259135A1 (en) | 2005-04-20 | 2006-11-16 | The Cleveland Clinic Foundation | Apparatus and method for replacing a cardiac valve |
SE531468C2 (sv) | 2005-04-21 | 2009-04-14 | Edwards Lifesciences Ag | En anordning för styrning av blodflöde |
EP1874954B1 (en) | 2005-04-27 | 2017-12-27 | Stout Medical Group, L.P. | Expandable support device |
US20070118207A1 (en) | 2005-05-04 | 2007-05-24 | Aga Medical Corporation | System for controlled delivery of stents and grafts |
EP1719476B1 (en) | 2005-05-06 | 2011-11-23 | Sorin Biomedica Cardio S.R.L. | Annuloplasty prosthesis |
US7824436B2 (en) | 2005-05-13 | 2010-11-02 | Benechill, Inc. | Methods and devices for non-invasive cerebral and systemic cooling |
US7914569B2 (en) | 2005-05-13 | 2011-03-29 | Medtronics Corevalve Llc | Heart valve prosthesis and methods of manufacture and use |
AU2006247571A1 (en) | 2005-05-13 | 2006-11-23 | Cook Incorporated | Medical device delivery systems that facilitate medical device placement in the presence of ultrasonic waves |
WO2006125055A2 (en) | 2005-05-17 | 2006-11-23 | Cook Incorporated | Prosthetic valve devices and methods of making and using such devices |
CN101175453B (zh) | 2005-05-17 | 2011-09-14 | 赛恩泰克公司 | 用于治疗心率调节系统疾患的装置和套件 |
EP2901967B1 (en) | 2005-05-24 | 2019-10-02 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
US8663312B2 (en) | 2005-05-27 | 2014-03-04 | Hlt, Inc. | Intravascular cuff |
CN101247773B (zh) | 2005-05-27 | 2010-12-15 | 心叶科技公司 | 无展伸件的支撑构件 |
US8211169B2 (en) | 2005-05-27 | 2012-07-03 | Medtronic, Inc. | Gasket with collar for prosthetic heart valves and methods for using them |
US7739971B2 (en) | 2005-06-07 | 2010-06-22 | Edwards Lifesciences Corporation | Systems and methods for assembling components of a fabric-covered prosthetic heart valve |
US8012198B2 (en) | 2005-06-10 | 2011-09-06 | Boston Scientific Scimed, Inc. | Venous valve, system, and method |
US7780723B2 (en) | 2005-06-13 | 2010-08-24 | Edwards Lifesciences Corporation | Heart valve delivery system |
US8685083B2 (en) | 2005-06-27 | 2014-04-01 | Edwards Lifesciences Corporation | Apparatus, system, and method for treatment of posterior leaflet prolapse |
US20060293698A1 (en) | 2005-06-28 | 2006-12-28 | Medtronic Vascular, Inc. | Retainer device for mitral valve leaflets |
US8663277B2 (en) | 2005-06-29 | 2014-03-04 | Ethicon, Inc. | Braided barbed suture |
WO2007022682A1 (fr) | 2005-07-08 | 2007-03-01 | Beijing Balance Medical Co. Ltd. | Pièce à valve et tube à valve pour réparer un vaisseau d’écoulement cardiaque |
WO2007009117A1 (en) | 2005-07-13 | 2007-01-18 | Arbor Surgical Technologies, Inc. | Two-piece percutaneous prosthetic heart valves and methods for making and using them |
US7682391B2 (en) | 2005-07-13 | 2010-03-23 | Edwards Lifesciences Corporation | Methods of implanting a prosthetic mitral heart valve having a contoured sewing ring |
DE102005032974B4 (de) | 2005-07-14 | 2013-11-07 | Siemens Aktiengesellschaft | Verfahren zur 3D-Visualisierung vaskulärer Einsatzstücke im menschlichen Körper mit dem C-Bogen |
WO2007011799A1 (en) | 2005-07-15 | 2007-01-25 | The Cleveland Clinic Foundation | Apparatus and method for remodeling a cardiac valve annulus |
US20090112309A1 (en) | 2005-07-21 | 2009-04-30 | The Florida International University Board Of Trustees | Collapsible Heart Valve with Polymer Leaflets |
US8790396B2 (en) | 2005-07-27 | 2014-07-29 | Medtronic 3F Therapeutics, Inc. | Methods and systems for cardiac valve delivery |
JP4809894B2 (ja) | 2005-07-29 | 2011-11-09 | シーブイデバイシズ リミテッド ライアビリティ カンパニー | 逆かん流カニューレを用いて血圧をコントロールする機器及び方法 |
WO2007016165A1 (en) | 2005-07-29 | 2007-02-08 | Cook Incorporated | Elliptical implantable device |
CA2601869A1 (en) | 2005-08-12 | 2007-02-22 | Astellas Pharma Inc. | Method for identifying target protein of agent and method for screening therapeutic agent for diabetes using target protein |
WO2007022519A2 (en) | 2005-08-19 | 2007-02-22 | Chf Technologies, Inc. | Steerable heart implants for congestive heart failure |
WO2007025028A1 (en) | 2005-08-25 | 2007-03-01 | The Cleveland Clinic Foundation | Percutaneous atrioventricular valve and method of use |
JP5188971B2 (ja) | 2005-08-25 | 2013-04-24 | メドトロニック ヴァスキュラー インコーポレイテッド | 生分解性医療機器の製造及び医療機器コーティングとして有益な4−アザ−カプロラクトンを基材としたポリマー組成物 |
US7455689B2 (en) | 2005-08-25 | 2008-11-25 | Edwards Lifesciences Corporation | Four-leaflet stented mitral heart valve |
US9492277B2 (en) | 2005-08-30 | 2016-11-15 | Mayo Foundation For Medical Education And Research | Soft body tissue remodeling methods and apparatus |
US20070061002A1 (en) | 2005-09-01 | 2007-03-15 | Cook Incorporated | Attachment of material to an implantable frame by cross-linking |
WO2007030063A1 (en) | 2005-09-07 | 2007-03-15 | Medtentia Ab | A device and method for improving the function of a heart valve |
US7530253B2 (en) | 2005-09-09 | 2009-05-12 | Edwards Lifesciences Corporation | Prosthetic valve crimping device |
US7712606B2 (en) | 2005-09-13 | 2010-05-11 | Sadra Medical, Inc. | Two-part package for medical implant |
DE102005044009A1 (de) | 2005-09-14 | 2007-03-22 | Biophan Europe Gmbh | Biologische oder künstliche Klappenprothese zur Verwendung im menschlichen und/oder tierischen Körper zum Einsatz einer Organklappe oder Gefäßklappe |
US7972359B2 (en) | 2005-09-16 | 2011-07-05 | Atritech, Inc. | Intracardiac cage and method of delivering same |
CA2622433A1 (en) | 2005-09-21 | 2007-04-05 | Medtronic, Inc. | Composite heart valve apparatus manufactured using techniques involving laser machining of tissue |
JP2009508622A (ja) | 2005-09-21 | 2009-03-05 | ビー−バルーン リミティド | 分岐バルーン及びステント |
US7569071B2 (en) | 2005-09-21 | 2009-08-04 | Boston Scientific Scimed, Inc. | Venous valve, system, and method with sinus pocket |
WO2007038540A1 (en) | 2005-09-26 | 2007-04-05 | Medtronic, Inc. | Prosthetic cardiac and venous valves |
US20070073391A1 (en) | 2005-09-28 | 2007-03-29 | Henry Bourang | System and method for delivering a mitral valve repair device |
FR2891134B1 (fr) | 2005-09-29 | 2008-08-22 | Jean Noel Fabiani | Prothese annulaire pour plastie valvulaire aortique, procede pour plastie valvulaire aortique et combinaison de la prothese annulaire et d'une prothese pour segment aortique |
US8048152B2 (en) | 2005-09-30 | 2011-11-01 | Medtronic, Inc. | Method of implanting an annuloplasty prosthesis |
US9011528B2 (en) | 2005-09-30 | 2015-04-21 | Medtronic, Inc. | Flexible annuloplasty prosthesis |
US20070129794A1 (en) | 2005-10-05 | 2007-06-07 | Fidel Realyvasquez | Method and apparatus for prosthesis attachment using discrete elements |
US9265605B2 (en) | 2005-10-14 | 2016-02-23 | Boston Scientific Scimed, Inc. | Bronchoscopic lung volume reduction valve |
US8167932B2 (en) | 2005-10-18 | 2012-05-01 | Edwards Lifesciences Corporation | Heart valve delivery system with valve catheter |
US7503928B2 (en) | 2005-10-21 | 2009-03-17 | Cook Biotech Incorporated | Artificial valve with center leaflet attachment |
US7563277B2 (en) | 2005-10-24 | 2009-07-21 | Cook Incorporated | Removable covering for implantable frame projections |
US8092525B2 (en) | 2005-10-26 | 2012-01-10 | Cardiosolutions, Inc. | Heart valve implant |
US8449606B2 (en) | 2005-10-26 | 2013-05-28 | Cardiosolutions, Inc. | Balloon mitral spacer |
JP4820875B2 (ja) | 2005-10-26 | 2011-11-24 | セント ジュード メディカル インコーポレイテッド | 非対称を備えるサドル形状僧帽弁輪状形成人工器官及び関連方法 |
DE102005051849B4 (de) | 2005-10-28 | 2010-01-21 | JenaValve Technology Inc., Wilmington | Vorrichtung zur Implantation und Befestigung von Herzklappenprothesen |
EP1951155B1 (en) | 2005-11-02 | 2021-05-12 | MedicalTree Patents Ltd. | Artificial valve for implantation |
DE102005052628B4 (de) | 2005-11-04 | 2014-06-05 | Jenavalve Technology Inc. | Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter |
FR2892939B1 (fr) | 2005-11-10 | 2010-01-22 | Groupement Coeur Artificiel Total Carpentier Matra Carmat | Materiau hemocompatible composite et son procede d'obtention |
EP1951352B1 (en) | 2005-11-10 | 2017-01-11 | Edwards Lifesciences CardiAQ LLC | Balloon-expandable, self-expanding, vascular prosthesis connecting stent |
CN100362971C (zh) | 2005-11-16 | 2008-01-23 | 程英升 | 贲门支架 |
US8764820B2 (en) | 2005-11-16 | 2014-07-01 | Edwards Lifesciences Corporation | Transapical heart valve delivery system and method |
JP2007136199A (ja) | 2005-11-16 | 2007-06-07 | Micardia Corp | 磁気係合カテーテルを備えた植え込み可能な装置 |
GB0524087D0 (en) | 2005-11-25 | 2006-01-04 | Symetis Ag | Biodegradable scaffold |
FR2894131B1 (fr) | 2005-12-02 | 2008-12-05 | Perouse Soc Par Actions Simpli | Dispositif de traitement d'un vaisseau sanguin, et necessaire de traitement associe. |
EP1959864B1 (en) | 2005-12-07 | 2018-03-07 | Medtronic, Inc. | Connection systems for two piece prosthetic heart valve assemblies |
US9125742B2 (en) | 2005-12-15 | 2015-09-08 | Georgia Tech Research Foundation | Papillary muscle position control devices, systems, and methods |
US7901454B2 (en) | 2005-12-15 | 2011-03-08 | The Cleveland Clinic Foundation | Apparatus and method for treating a regurgitant valve |
EP3398560B8 (en) | 2005-12-22 | 2024-01-10 | Boston Scientific Medical Device Limited | Systems for surgery and stent valves for replacement |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
RU2302220C1 (ru) | 2005-12-23 | 2007-07-10 | Александр Петрович Мельников | Протез клапана сердца |
WO2007072469A2 (en) | 2005-12-23 | 2007-06-28 | Vysera Biomedical Limited | A medical device suitable for treating reflux from a stomach to an oesophagus |
DE602005015238D1 (de) | 2005-12-28 | 2009-08-13 | Sorin Biomedica Cardio Srl | Prothese für Annuloplastie mit auxetischer Struktur |
TW200731980A (en) | 2005-12-29 | 2007-09-01 | Alcon Mfg Ltd | RNAi-mediated inhibition of HIF1A for treatment of ocular angiogenesis |
US8777975B2 (en) | 2005-12-30 | 2014-07-15 | C.R. Bard, Inc. | Embolus blood clot filter with bio-resorbable coated filter members |
US20090069902A1 (en) | 2006-01-04 | 2009-03-12 | Nanopowers S.A. | Artificial contractile tissue |
US9717468B2 (en) | 2006-01-10 | 2017-08-01 | Mediguide Ltd. | System and method for positioning an artificial heart valve at the position of a malfunctioning valve of a heart through a percutaneous route |
US7799038B2 (en) | 2006-01-20 | 2010-09-21 | Boston Scientific Scimed, Inc. | Translumenal apparatus, system, and method |
US8083792B2 (en) | 2006-01-24 | 2011-12-27 | Cordis Corporation | Percutaneous endoprosthesis using suprarenal fixation and barbed anchors |
USD553747S1 (en) | 2006-01-25 | 2007-10-23 | Cornova, Inc. | Stent device |
US7627376B2 (en) | 2006-01-30 | 2009-12-01 | Medtronic, Inc. | Intravascular medical device |
US20090227992A1 (en) | 2006-02-02 | 2009-09-10 | Releaf Medical Ltd | Shock-Wave Generating Device, Such as for the Treatment of Calcific Aortic Stenosis |
US7637946B2 (en) | 2006-02-09 | 2009-12-29 | Edwards Lifesciences Corporation | Coiled implant for mitral valve repair |
EP1988851A2 (en) | 2006-02-14 | 2008-11-12 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
EP2583640B1 (en) | 2006-02-16 | 2022-06-22 | Venus MedTech (HangZhou), Inc. | Minimally invasive replacement heart valve |
US7910152B2 (en) | 2006-02-28 | 2011-03-22 | Advanced Cardiovascular Systems, Inc. | Poly(ester amide)-based drug delivery systems with controlled release rate and morphology |
US8043673B2 (en) | 2006-03-02 | 2011-10-25 | Boston Scientific Scimed, Inc. | Method to make tube-in-tube balloon |
US8219229B2 (en) | 2006-03-02 | 2012-07-10 | Edwards Lifesciences Corporation | Virtual heart valve |
US7431692B2 (en) | 2006-03-09 | 2008-10-07 | Edwards Lifesciences Corporation | Apparatus, system, and method for applying and adjusting a tensioning element to a hollow body organ |
ITMI20060436A1 (it) | 2006-03-10 | 2007-09-11 | Clay Paky Spa | Proiettore da palcoscenico |
EP1998719A1 (en) | 2006-03-10 | 2008-12-10 | Arbor Surgical Technologies, Inc. | Valve introducers and methods for making and using them |
DE102006013113B4 (de) | 2006-03-22 | 2008-12-11 | Vielberg, Heinrich, Dr. med. | Ventilgetriebe |
US8075615B2 (en) | 2006-03-28 | 2011-12-13 | Medtronic, Inc. | Prosthetic cardiac valve formed from pericardium material and methods of making same |
US7691151B2 (en) | 2006-03-31 | 2010-04-06 | Spiration, Inc. | Articulable Anchor |
RU2325874C2 (ru) | 2006-04-04 | 2008-06-10 | Александр Васильевич Самков | Протез клапана сердца |
FR2899096B1 (fr) | 2006-04-04 | 2008-12-05 | Perouse Soc Par Actions Simpli | Dispositif de traitement d'un conduit de circulation du sang et procede de preparation de ce dispositif |
US20070244556A1 (en) | 2006-04-12 | 2007-10-18 | Medtronic Vascular, Inc. | Annuloplasty Device Having a Helical Anchor and Methods for its Use |
US7806926B2 (en) | 2006-04-14 | 2010-10-05 | Edwards Lifesciences Corporation | Holders for prosthetic aortic heart valves |
EP2007313B1 (en) | 2006-04-19 | 2018-05-16 | Cook Medical Technologies, LLC | Stent graft |
US20070250151A1 (en) | 2006-04-24 | 2007-10-25 | Scimed Life Systems, Inc. | Endovascular aortic repair delivery system with anchor |
US8551161B2 (en) | 2006-04-25 | 2013-10-08 | Medtronic Vascular, Inc. | Cardiac valve annulus restraining device |
US8652201B2 (en) | 2006-04-26 | 2014-02-18 | The Cleveland Clinic Foundation | Apparatus and method for treating cardiovascular diseases |
US20070255394A1 (en) | 2006-04-28 | 2007-11-01 | Medtronic, Inc. | Method and apparatus for cardiac valve replacement |
WO2007130881A2 (en) | 2006-04-29 | 2007-11-15 | Arbor Surgical Technologies, Inc. | Multiple component prosthetic heart valve assemblies and apparatus and methods for delivering them |
JP5016667B2 (ja) | 2006-04-29 | 2012-09-05 | メドトロニック,インコーポレイテッド | 複数部材の人工心臓弁アセンブリ並びにそれを用いた装置及びその使用方法 |
US8070800B2 (en) | 2006-05-05 | 2011-12-06 | Children's Medical Center Corporation | Transcatheter heart valve prostheses |
GB2437921B (en) | 2006-05-10 | 2011-08-03 | Francis Wells | Heart valve repair |
US8986713B2 (en) | 2006-05-12 | 2015-03-24 | W. L. Gore & Associates, Inc. | Medical device capable of being compacted and expanded having anti-thrombin III binding activity |
EP2020964B1 (en) | 2006-05-12 | 2010-12-15 | EV3, Inc. | Implant and delivery system with multiple marker interlocks |
WO2007131513A1 (en) | 2006-05-15 | 2007-11-22 | Enovacor Aps | A system and a method for altering the geometry of the heart |
WO2007131553A1 (en) | 2006-05-17 | 2007-11-22 | Syntach Ag | A controllable device, a kit and a method for treatment of disorders in the heart rhythm regulation system |
FR2901146A1 (fr) | 2006-05-18 | 2007-11-23 | Ela Medical Soc Par Actions Si | Dispositif medical implantable actif de stimulation cardiaque, resynchronisation, cardioversion et/ou defibrillation, comportant des moyens de detection d'artefacts de bruit ventriculaire |
US8932348B2 (en) | 2006-05-18 | 2015-01-13 | Edwards Lifesciences Corporation | Device and method for improving heart valve function |
US8753384B2 (en) | 2006-05-19 | 2014-06-17 | Boston Scientific Scimed, Inc. | Apparatus and method for loading and delivering a stent |
US8535368B2 (en) | 2006-05-19 | 2013-09-17 | Boston Scientific Scimed, Inc. | Apparatus for loading and delivering a stent |
CA2654359A1 (en) | 2006-05-19 | 2007-11-29 | Mitralsolutions, Inc. | Implantable devices for controlling the size and shape of an anatomical structure or lumen |
US20090270972A1 (en) | 2006-05-23 | 2009-10-29 | All-Vascular Pty Ltd. | Endovenous valve transfer stent |
AU2007268123A1 (en) | 2006-05-25 | 2007-12-06 | Deep Vein Medical, Inc. | Device for regulating blood flow |
US7959940B2 (en) | 2006-05-30 | 2011-06-14 | Advanced Cardiovascular Systems, Inc. | Polymer-bioceramic composite implantable medical devices |
AU2007255072A1 (en) | 2006-05-30 | 2007-12-13 | Cook Incorporated | Artificial valve prosthesis |
WO2007138571A2 (en) | 2006-06-01 | 2007-12-06 | Mor Research Applications Ltd. | Membrane augmentation, such as of for treatment of cardiac valves, and fastening devices for membrane augmentation |
US8197538B2 (en) | 2006-06-02 | 2012-06-12 | Medtronic, Inc. | Annuloplasty prosthesis with in vivo shape identification and related methods of use |
JP2009539422A (ja) | 2006-06-02 | 2009-11-19 | メドトロニック・インコーポレーテッド | 弁輪形成用リング及び形成術 |
US9259336B2 (en) | 2006-06-06 | 2016-02-16 | Cook Medical Technologies Llc | Stent with a crush-resistant zone |
ITTO20060413A1 (it) | 2006-06-07 | 2007-12-08 | Arrigo Lessana | Dispositivo sostitutivo delle corde tendinee di una valvola atrioventricolare |
EP1864687B1 (en) | 2006-06-09 | 2013-07-31 | Eidgenössische Technische Hochschule Zürich | Scaffolds for artificial heart valves and vascular structures |
US8778376B2 (en) | 2006-06-09 | 2014-07-15 | Advanced Cardiovascular Systems, Inc. | Copolymer comprising elastin pentapeptide block and hydrophilic block, and medical device and method of treating |
US8114150B2 (en) | 2006-06-14 | 2012-02-14 | Advanced Cardiovascular Systems, Inc. | RGD peptide attached to bioabsorbable stents |
EP2059191A4 (en) | 2006-06-21 | 2010-03-31 | Aortx Inc | PROSTHETIC VALVE IMPLANTATION SYSTEMS |
DE102006028533A1 (de) | 2006-06-21 | 2008-01-03 | Iprm Intellectual Property Rights Management Ag | Vorrichtung und Computerprogramm zum Bestimmen eines Lungenzustands eines Patienten, welcher durch ein kardiopulmonales Blutvolumen dargestellt wird |
US8128688B2 (en) | 2006-06-27 | 2012-03-06 | Abbott Cardiovascular Systems Inc. | Carbon coating on an implantable device |
US8449605B2 (en) | 2006-06-28 | 2013-05-28 | Kardium Inc. | Method for anchoring a mitral valve |
US20080004696A1 (en) | 2006-06-29 | 2008-01-03 | Valvexchange Inc. | Cardiovascular valve assembly with resizable docking station |
US20080077231A1 (en) | 2006-07-06 | 2008-03-27 | Prescient Medical, Inc. | Expandable vascular endoluminal prostheses |
WO2008005666A1 (en) | 2006-07-07 | 2008-01-10 | Boston Scientific Limited | Endoprosthesis delivery system with stent holder |
JP4981374B2 (ja) | 2006-07-10 | 2012-07-18 | パーパス株式会社 | 細胞又は組織の培養装置及び培養方法 |
US8685430B1 (en) | 2006-07-14 | 2014-04-01 | Abbott Cardiovascular Systems Inc. | Tailored aliphatic polyesters for stent coatings |
US20080021546A1 (en) | 2006-07-18 | 2008-01-24 | Tim Patz | System for deploying balloon-expandable heart valves |
RU2325873C2 (ru) | 2006-07-20 | 2008-06-10 | Александр Васильевич Самков | Створка искусственного клапана сердца и способ ее изготовления |
WO2008013915A2 (en) | 2006-07-28 | 2008-01-31 | Arshad Quadri | Percutaneous valve prosthesis and system and method for implanting same |
GB2440809B (en) | 2006-07-28 | 2011-08-10 | Geoffrey Douglas Tansley | Improved heart valve prosthesis |
US8020503B2 (en) | 2006-07-31 | 2011-09-20 | Edwards Lifesciences Corporation | Automated surgical implant sewing system and method |
US8454684B2 (en) | 2006-08-02 | 2013-06-04 | Medtronic, Inc. | Heart valve holder for use in valve implantation procedures |
US7871432B2 (en) | 2006-08-02 | 2011-01-18 | Medtronic, Inc. | Heart valve holder for use in valve implantation procedures |
US7363821B2 (en) | 2006-08-28 | 2008-04-29 | Cordis Corporation | Systems and methods for fatigue testing stents |
US20080058924A1 (en) | 2006-09-01 | 2008-03-06 | Aaron Ingle | Saddle-shaped annuloplasty ring |
EP2063823B1 (en) | 2006-09-01 | 2018-10-31 | Carag AG | Devices, system, kit and method for epicardial access |
CN102247223B (zh) | 2006-09-08 | 2015-05-06 | 爱德华兹生命科学公司 | 一体的心脏瓣膜运送系统 |
US8460335B2 (en) | 2006-09-11 | 2013-06-11 | Embrella Cardiovascular, Inc. | Method of deflecting emboli from the cerebral circulation |
US20100179647A1 (en) | 2006-09-11 | 2010-07-15 | Carpenter Judith T | Methods of reducing embolism to cerebral circulation as a consequence of an index cardiac procedure |
US8834564B2 (en) | 2006-09-19 | 2014-09-16 | Medtronic, Inc. | Sinus-engaging valve fixation member |
US8052750B2 (en) | 2006-09-19 | 2011-11-08 | Medtronic Ventor Technologies Ltd | Valve prosthesis fixation techniques using sandwiching |
US9211115B2 (en) | 2006-09-28 | 2015-12-15 | Bioventrix, Inc. | Location, time, and/or pressure determining devices, systems, and methods for deployment of lesion-excluding heart implants for treatment of cardiac heart failure and other disease states |
FR2906454B1 (fr) | 2006-09-28 | 2009-04-10 | Perouse Soc Par Actions Simpli | Implant destine a etre place dans un conduit de circulation du sang. |
CA2664662A1 (en) | 2006-09-28 | 2008-04-03 | Heart Leaflet Technologies, Inc. | Delivery tool for percutaneous delivery of a prosthesis |
US7534261B2 (en) | 2006-10-02 | 2009-05-19 | Edwards Lifesciences Corporation | Sutureless heart valve attachment |
US7575592B2 (en) | 2006-10-03 | 2009-08-18 | St. Jude Medical, Inc. | Synthetic blood vessel grafts |
US8029556B2 (en) | 2006-10-04 | 2011-10-04 | Edwards Lifesciences Corporation | Method and apparatus for reshaping a ventricle |
US8163011B2 (en) | 2006-10-06 | 2012-04-24 | BioStable Science & Engineering, Inc. | Intra-annular mounting frame for aortic valve repair |
FR2906998B1 (fr) | 2006-10-16 | 2009-04-10 | Perouse Soc Par Actions Simpli | Implant destine a etre place dans un conduit de circulation du sang. |
WO2008047354A2 (en) | 2006-10-16 | 2008-04-24 | Ventor Technologies Ltd. | Transapical delivery system with ventriculo-arterial overflow bypass |
US8388680B2 (en) | 2006-10-18 | 2013-03-05 | Guided Delivery Systems, Inc. | Methods and devices for catheter advancement and delivery of substances therethrough |
US20080097571A1 (en) | 2006-10-21 | 2008-04-24 | Paragon Intellectual Properties, Llc | Deformable lumen support devices and methods of use |
CA2666485C (en) | 2006-10-27 | 2015-10-06 | Edwards Lifesciences Corporation | Biological tissue for surgical implantation |
DE102006052564B3 (de) | 2006-11-06 | 2007-12-13 | Georg Lutter | Mitralklappenstent |
US10624621B2 (en) | 2006-11-07 | 2020-04-21 | Corvia Medical, Inc. | Devices and methods for the treatment of heart failure |
EP2081515B1 (en) | 2006-11-07 | 2015-10-21 | Cook Medical Technologies LLC | Fenestrations for stent graft arrangements and stent graft including the same |
EP1920789A1 (en) | 2006-11-11 | 2008-05-14 | Universitätsklinikum Hamburg-Eppendorf | Pouch-like construct comprising mammalian tissue |
SE530568C2 (sv) | 2006-11-13 | 2008-07-08 | Medtentia Ab | Anordning och metod för förbättring av funktionen hos en hjärtklaff |
EP2091465B1 (en) | 2006-11-14 | 2018-01-31 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | Coronary artery and myocardial protection device |
US7615072B2 (en) | 2006-11-14 | 2009-11-10 | Medtronic Vascular, Inc. | Endoluminal prosthesis |
WO2010004546A1 (en) | 2008-06-16 | 2010-01-14 | Valtech Cardio, Ltd. | Annuloplasty devices and methods of delivery therefor |
US8926695B2 (en) | 2006-12-05 | 2015-01-06 | Valtech Cardio, Ltd. | Segmented ring placement |
EP2104470B1 (en) | 2006-12-06 | 2022-10-26 | Medtronic Corevalve, LLC. | System and method for transapical delivery of an annulus anchored self-expanding valve |
FR2909857B1 (fr) | 2006-12-14 | 2009-03-06 | Perouse Soc Par Actions Simpli | Endovalve. |
US8070799B2 (en) | 2006-12-19 | 2011-12-06 | Sorin Biomedica Cardio S.R.L. | Instrument and method for in situ deployment of cardiac valve prostheses |
EP1967164A3 (en) | 2006-12-19 | 2009-01-28 | Sorin Biomedica Cardio S.R.L. | Instrument for in situ deployment of cardiac valve prostheses |
WO2008079272A2 (en) | 2006-12-19 | 2008-07-03 | St. Jude Medical, Inc. | Prosthetic heart valve including stent structure and tissue leaflets, and related methods |
US8057539B2 (en) | 2006-12-19 | 2011-11-15 | Sorin Biomedica Cardio S.R.L. | System for in situ positioning of cardiac valve prostheses without occluding blood flow |
FR2910269B1 (fr) | 2006-12-22 | 2009-02-27 | Corevalve Inc | Materiel de traitement d'une valve cardiaque,en particulier d'une valve mitrale |
US8236045B2 (en) | 2006-12-22 | 2012-08-07 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method of making the same |
US9107750B2 (en) | 2007-01-03 | 2015-08-18 | St. Jude Medical, Cardiology Division, Inc. | Implantable devices for controlling the size and shape of an anatomical structure or lumen |
EP1943942B1 (en) | 2007-01-15 | 2010-01-06 | Jen-Ping Chang | Examining device for examining an aortic valve and a pulmonary valve competency |
EP2111190B1 (en) | 2007-01-19 | 2013-10-09 | Medtronic, Inc. | Stented heart valve devices for atrioventricular valve replacement |
US8105375B2 (en) | 2007-01-19 | 2012-01-31 | The Cleveland Clinic Foundation | Method for implanting a cardiovascular valve |
WO2008094469A2 (en) | 2007-01-26 | 2008-08-07 | Medtronic, Inc. | Annuloplasty device for tricuspid valve repair |
DE102007005900A1 (de) | 2007-02-01 | 2008-08-07 | Endosmart Gesellschaft für innovative Medizintechnik mbH | Instrument zum operativen Entfernen einer defekten Herzklappe |
EP2117469B1 (en) | 2007-02-05 | 2014-07-09 | Boston Scientific Limited | Percutaneous valve system |
CA2669564A1 (en) | 2007-02-05 | 2008-08-14 | Boston Scientific Limited | Synthetic composite structures |
US7967853B2 (en) | 2007-02-05 | 2011-06-28 | Boston Scientific Scimed, Inc. | Percutaneous valve, system and method |
US9415567B2 (en) | 2007-02-05 | 2016-08-16 | Boston Scientific Scimed, Inc. | Synthetic composite structures |
CN101605511B (zh) | 2007-02-09 | 2013-03-13 | 爱德华兹生命科学公司 | 大小逐渐变化的瓣环成形术环 |
WO2008101113A1 (en) | 2007-02-14 | 2008-08-21 | Edwards Lifesciences Corporation | Suture and method for repairing heart |
CA2677633C (en) | 2007-02-15 | 2015-09-08 | Medtronic, Inc. | Multi-layered stents and methods of implanting |
EP2120795B1 (en) | 2007-02-15 | 2011-07-06 | Cook Incorporated | Artificial valve prostheses with a free leaflet portion |
WO2008098777A1 (de) | 2007-02-16 | 2008-08-21 | Universität Zürich | Rohrförmige stützprothese mit herzklappe insbesondere für aortenklappenersatz |
EP2129332B1 (en) | 2007-02-16 | 2019-01-23 | Medtronic, Inc. | Replacement prosthetic heart valves |
EP1958598A1 (de) | 2007-02-16 | 2008-08-20 | Universität Zürich | Wachstumsfähige, rohrförmige Stützprothese |
DE102007010305A1 (de) | 2007-02-22 | 2008-08-28 | Jotec Gmbh | Vorrichtung zum Freisetzen eines selbstexpandierenden Stents in ein Körpergefäß |
US8221505B2 (en) | 2007-02-22 | 2012-07-17 | Cook Medical Technologies Llc | Prosthesis having a sleeve valve |
US8070802B2 (en) * | 2007-02-23 | 2011-12-06 | The Trustees Of The University Of Pennsylvania | Mitral valve system |
US7753949B2 (en) | 2007-02-23 | 2010-07-13 | The Trustees Of The University Of Pennsylvania | Valve prosthesis systems and methods |
US20080208327A1 (en) | 2007-02-27 | 2008-08-28 | Rowe Stanton J | Method and apparatus for replacing a prosthetic valve |
US8100959B2 (en) | 2007-03-09 | 2012-01-24 | Pulmonx Corporation | Loading device for a pulmonary implant |
US8303622B2 (en) | 2007-03-14 | 2012-11-06 | St. Jude Medical, Inc. | Heart valve chordae replacement methods and apparatus |
FR2913879B1 (fr) | 2007-03-21 | 2009-06-12 | Perouse Soc Par Actions Simpli | Dispositif de largage d'un implant expansible radialement, necessaire de traitement et procede de largage associe |
US8653632B2 (en) | 2007-03-28 | 2014-02-18 | Medtronic Ats Medical Inc. | System and method for conditioning implantable medical devices |
AU2007351026B2 (en) | 2007-04-13 | 2012-04-05 | Jenavalve Technology Inc. | Medical device for treating a heart valve insufficiency or stenosis |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
WO2008125145A1 (en) | 2007-04-13 | 2008-10-23 | Synergio Ag | A tissue penetration device and method |
US9138315B2 (en) | 2007-04-13 | 2015-09-22 | Jenavalve Technology Gmbh | Medical device for treating a heart valve insufficiency or stenosis |
US7806917B2 (en) | 2007-04-17 | 2010-10-05 | Medtronic Vascular, Inc. | Stent graft fixation system and method |
US8433422B2 (en) | 2007-04-20 | 2013-04-30 | Medtronic, Inc. | Implantable medical electrical lead and connector assembly |
JP5264264B2 (ja) | 2007-04-23 | 2013-08-14 | セント ジョセフズ トランスレーショナル リサーチ インスティテュート インコーポレイテッド | 交換用心臓弁およびその製造方法 |
US20080262603A1 (en) | 2007-04-23 | 2008-10-23 | Sorin Biomedica Cardio | Prosthetic heart valve holder |
US8409274B2 (en) | 2007-04-26 | 2013-04-02 | St. Jude Medical, Inc. | Techniques for attaching flexible leaflets of prosthetic heart valves to supporting structures |
US8529620B2 (en) | 2007-05-01 | 2013-09-10 | Ottavio Alfieri | Inwardly-bowed tricuspid annuloplasty ring |
FR2915678B1 (fr) | 2007-05-02 | 2010-04-16 | Lapeyre Ind Llc | Valve cardiaque prothetique mecanique |
US8147504B2 (en) | 2007-05-05 | 2012-04-03 | Medtronic, Inc. | Apparatus and methods for delivering fasteners during valve replacement |
FR2915903B1 (fr) | 2007-05-10 | 2010-06-04 | Carpentier Matra Carmat | Procede pour la realisation d'un objet hemocompatible de configuration complexe et objet ainsi obtenu. |
US8480730B2 (en) | 2007-05-14 | 2013-07-09 | Cardiosolutions, Inc. | Solid construct mitral spacer |
AU2008250552B2 (en) | 2007-05-15 | 2012-03-08 | Jenavalve Technology Inc. | Handle for manipulating a catheter tip, catheter system and medical insertion system for inserting a self-expandable heart valve stent |
US8403979B2 (en) | 2007-05-17 | 2013-03-26 | Cook Medical Technologies Llc | Monocuspid prosthetic valve having a partial sinus |
EP1994912B1 (en) | 2007-05-21 | 2010-03-03 | Berardino Della Sala | Electromagnetically closable non-return valve for biological liquid pumps |
FR2916627B1 (fr) | 2007-05-30 | 2010-09-17 | Perouse Lab | Necessaire de traitement d'un conduit de circulation du sang |
US9572660B2 (en) | 2007-06-04 | 2017-02-21 | St. Jude Medical, Inc. | Prosthetic heart valves |
FR2916959B1 (fr) | 2007-06-08 | 2009-09-04 | Perouse Soc Par Actions Simpli | Necessaire destine a etre implante dans un conduit de circulation de sang |
US8425591B1 (en) | 2007-06-11 | 2013-04-23 | Abbott Cardiovascular Systems Inc. | Methods of forming polymer-bioceramic composite medical devices with bioceramic particles |
US9101691B2 (en) | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
ES2475144T3 (es) | 2007-06-26 | 2014-07-10 | St. Jude Medical, Inc. | Aparato para la implantación de válvulas prot�sicas de corazón replegables / expansibles |
DE102007031148A1 (de) | 2007-06-27 | 2009-01-08 | Aesculap Ag | Aortensinusprothese |
DE102007031146A1 (de) | 2007-06-27 | 2009-01-08 | Aesculap Ag | Sinusflicken zum Ersatz von defekten Sinus an der Aortenwurzel |
US8006535B2 (en) | 2007-07-12 | 2011-08-30 | Sorin Biomedica Cardio S.R.L. | Expandable prosthetic valve crimping device |
DE602007009082D1 (de) | 2007-07-12 | 2010-10-21 | Sorin Biomedica Cardio Srl | Komprimierungsvorrichtung für eine erweiterbare Herzklappenprothese |
US8852620B2 (en) | 2007-07-20 | 2014-10-07 | Medtronic Vascular, Inc. | Medical devices comprising polymeric drug delivery systems with drug solubility gradients |
US8663319B2 (en) | 2007-07-23 | 2014-03-04 | Hocor Cardiovascular Technologies Llc | Methods and apparatus for percutaneous aortic valve replacement |
US9308086B2 (en) | 2010-09-21 | 2016-04-12 | Hocor Cardiovascular Technologies Llc | Method and system for balloon counterpulsation during aortic valve replacement |
US8663318B2 (en) | 2007-07-23 | 2014-03-04 | Hocor Cardiovascular Technologies Llc | Method and apparatus for percutaneous aortic valve replacement |
US8828079B2 (en) | 2007-07-26 | 2014-09-09 | Boston Scientific Scimed, Inc. | Circulatory valve, system and method |
US8182829B2 (en) | 2007-07-27 | 2012-05-22 | Abbott Cardiovascular Systems Inc. | Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat |
US9566178B2 (en) | 2010-06-24 | 2017-02-14 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US8961589B2 (en) | 2007-08-01 | 2015-02-24 | Abbott Cardiovascular Systems Inc. | Bioabsorbable coating with tunable hydrophobicity |
US8747458B2 (en) | 2007-08-20 | 2014-06-10 | Medtronic Ventor Technologies Ltd. | Stent loading tool and method for use thereof |
EP3045147B8 (en) | 2007-08-21 | 2017-05-31 | Symetis SA | A replacement valve |
JP5329542B2 (ja) | 2007-08-23 | 2013-10-30 | ダイレクト フロウ メディカル、 インク. | インプレース形成支持部を有する経腔的に移植可能な心臓弁 |
JP5419875B2 (ja) | 2007-08-24 | 2014-02-19 | セント ジュード メディカル インコーポレイテッド | 人工大動脈心臓弁 |
US8834551B2 (en) | 2007-08-31 | 2014-09-16 | Rex Medical, L.P. | Vascular device with valve for approximating vessel wall |
US20090093876A1 (en) | 2007-08-31 | 2009-04-09 | Edwards Lifesciences Corporation | Recoil inhibitor for prosthetic valve |
US8092363B2 (en) | 2007-09-05 | 2012-01-10 | Mardil, Inc. | Heart band with fillable chambers to modify heart valve function |
EP2185107B1 (en) | 2007-09-07 | 2017-01-25 | Edwards Lifesciences Corporation | Active holder for annuloplasty ring delivery |
US8114154B2 (en) | 2007-09-07 | 2012-02-14 | Sorin Biomedica Cardio S.R.L. | Fluid-filled delivery system for in situ deployment of cardiac valve prostheses |
EP2033593B1 (en) | 2007-09-07 | 2012-10-31 | Sorin Biomedica Cardio S.R.L. | "Microprocessor controlled delivery system for cardiac valve prosthesis" |
FR2932376B1 (fr) | 2008-06-11 | 2011-04-01 | Perouse Lab | Dispositif de traitement d'un conduit de circulation du sang |
FR2920664B1 (fr) | 2007-09-11 | 2010-09-10 | Perouse Lab | Dispositif de traitement d'un conduit de circulation du sang |
US8906081B2 (en) | 2007-09-13 | 2014-12-09 | W. L. Gore & Associates, Inc. | Stented vascular graft |
DE102007043830A1 (de) | 2007-09-13 | 2009-04-02 | Lozonschi, Lucian, Madison | Herzklappenstent |
US8220121B2 (en) | 2007-09-14 | 2012-07-17 | Cook Medical Technologies Llc | Device for loading a self-expandable prosthesis into a sheath |
US8273118B2 (en) | 2007-09-17 | 2012-09-25 | Medtronic, Inc. | Heart valve holder assembly for use in valve implantation procedures |
US20090076531A1 (en) | 2007-09-18 | 2009-03-19 | Richardson Charles L | Method and apparatus for bypass graft |
US20090082847A1 (en) | 2007-09-26 | 2009-03-26 | Boston Scientific Corporation | System and method of securing stent barbs |
US8066755B2 (en) | 2007-09-26 | 2011-11-29 | Trivascular, Inc. | System and method of pivoted stent deployment |
DE202008018589U1 (de) | 2007-09-26 | 2016-03-14 | St. Jude Medical, Inc. | Zusammenfaltbare Herzklappenprothesen |
US8454686B2 (en) | 2007-09-28 | 2013-06-04 | St. Jude Medical, Inc. | Two-stage collapsible/expandable prosthetic heart valves and anchoring systems |
US8784481B2 (en) | 2007-09-28 | 2014-07-22 | St. Jude Medical, Inc. | Collapsible/expandable prosthetic heart valves with native calcified leaflet retention features |
US8998978B2 (en) | 2007-09-28 | 2015-04-07 | Abbott Cardiovascular Systems Inc. | Stent formed from bioerodible metal-bioceramic composite |
US8180428B2 (en) | 2007-10-03 | 2012-05-15 | Medtronic, Inc. | Methods and systems for use in selecting cardiac pacing sites |
US9040646B2 (en) | 2007-10-04 | 2015-05-26 | W. L. Gore & Associates, Inc. | Expandable TFE copolymers, methods of making, and porous, expanded articles thereof |
US20090138079A1 (en) | 2007-10-10 | 2009-05-28 | Vector Technologies Ltd. | Prosthetic heart valve for transfemoral delivery |
US8136230B2 (en) | 2007-10-12 | 2012-03-20 | Spiration, Inc. | Valve loader method, system, and apparatus |
US8043301B2 (en) | 2007-10-12 | 2011-10-25 | Spiration, Inc. | Valve loader method, system, and apparatus |
CA2702672C (en) | 2007-10-15 | 2016-03-15 | Edwards Lifesciences Corporation | Transcatheter heart valve with micro-anchors |
US20090105813A1 (en) | 2007-10-17 | 2009-04-23 | Sean Chambers | Implantable valve device |
US20090157161A1 (en) | 2007-10-24 | 2009-06-18 | Edwards Lifesciences Corporation | Percutaneous Nitinol Stent Extraction Device |
BRPI0819217B8 (pt) | 2007-10-25 | 2021-06-22 | Symetis Sa | válvula de substituição para uso dentro de um corpo humano, sistema para substituir uma válvula dentro de um corpo humano e sistema de liberação da válvula cardíaca com stent |
US8009887B2 (en) | 2007-11-02 | 2011-08-30 | Siemens Corporation | Method and system for automatic quantification of aortic valve function from 4D computed tomography data using a physiological model |
ES2380555T3 (es) | 2007-11-05 | 2012-05-16 | St. Jude Medical, Inc. | Válvulas protésicas del corazón plegables/expansibles con soportes de stent no expansible y características de recuperación |
US8715337B2 (en) | 2007-11-09 | 2014-05-06 | Cook Medical Technologies Llc | Aortic valve stent graft |
US20090125096A1 (en) | 2007-11-12 | 2009-05-14 | Medtronic Vascular, Inc. | Stent Graft With Pins |
EP2222247B1 (en) | 2007-11-19 | 2012-08-22 | Cook Medical Technologies LLC | Valve frame |
US8784483B2 (en) | 2007-11-19 | 2014-07-22 | The Cleveland Clinic Foundation | Apparatus and method for treating a regurgitant heart valve |
US20090149946A1 (en) | 2007-12-05 | 2009-06-11 | Cook Incorporated | Stent having at least one barb and methods of manufacture |
US20090148491A1 (en) | 2007-12-05 | 2009-06-11 | Abbott Cardiovascular Systems Inc. | Dual-Targeted Drug Carriers |
DE102007061301A1 (de) | 2007-12-10 | 2009-06-18 | Aesculap Ag | Ummantelung zur Wiederherstellung der Klappenfunktion variköser Venen und Verwendung der Ummantelung in der Chirurgie |
DK2628464T3 (da) | 2007-12-14 | 2020-03-09 | Edwards Lifesciences Corp | Proteseklap |
US7892276B2 (en) | 2007-12-21 | 2011-02-22 | Boston Scientific Scimed, Inc. | Valve with delayed leaflet deployment |
US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
EP2072027B1 (en) | 2007-12-21 | 2020-06-17 | Medtentia International Ltd Oy | pre-annuloplasty device and method |
US9370437B2 (en) | 2007-12-26 | 2016-06-21 | Cook Medical Technologies Llc | Stent having less invasive ends |
US20090171456A1 (en) | 2007-12-28 | 2009-07-02 | Kveen Graig L | Percutaneous heart valve, system, and method |
AU2009204516A1 (en) | 2008-01-04 | 2009-07-16 | Interventional & Surgical Innovations, Llc | Device for regulating blood flow |
US8926688B2 (en) | 2008-01-11 | 2015-01-06 | W. L. Gore & Assoc. Inc. | Stent having adjacent elements connected by flexible webs |
WO2009091718A1 (en) | 2008-01-14 | 2009-07-23 | Boston Scientific Scimed, Inc. | Stent delivery device with luer or clamp-type suture release apparatus |
AU2009205739B2 (en) | 2008-01-16 | 2014-09-25 | St. Jude Medical, Inc. | Delivery and retrieval systems for collapsible/expandable prosthetic heart valves |
EP2254514B1 (en) | 2008-01-24 | 2018-10-03 | Medtronic, Inc | Stents for prosthetic heart valves |
US8628566B2 (en) | 2008-01-24 | 2014-01-14 | Medtronic, Inc. | Stents for prosthetic heart valves |
US8157852B2 (en) | 2008-01-24 | 2012-04-17 | Medtronic, Inc. | Delivery systems and methods of implantation for prosthetic heart valves |
AU2009206340B2 (en) | 2008-01-24 | 2012-06-14 | Medtronic Vascular Inc. | Infundibular reducer device delivery system and related methods |
WO2009094501A1 (en) | 2008-01-24 | 2009-07-30 | Medtronic, Inc. | Markers for prosthetic heart valves |
EP2082690B1 (en) | 2008-01-24 | 2012-06-20 | Kardium, Inc. | Medical device to assist diastolic function and prevent ventricular enlargement |
US7993395B2 (en) | 2008-01-25 | 2011-08-09 | Medtronic, Inc. | Set of annuloplasty devices with varying anterior-posterior ratios and related methods |
EP2249711B1 (en) | 2008-02-06 | 2021-10-06 | Ancora Heart, Inc. | Multi-window guide tunnel |
AU2009210744B2 (en) | 2008-02-08 | 2014-06-12 | Heartware, Inc. | Ventricular assist device for intraventricular placement |
WO2009101617A2 (en) | 2008-02-11 | 2009-08-20 | Corassist Cardiovascular Ltd. | Ventricular function assisting devices and methods of use thereof |
GB0803302D0 (en) | 2008-02-22 | 2008-04-02 | Barts & London Nhs Trust | Blood vessel prosthesis and delivery apparatus |
JP2011512948A (ja) | 2008-02-25 | 2011-04-28 | メドトロニック カルディオ ヴァスキュラー インコーポレイテッド | 漏斗部整復器具 |
ES2488119T3 (es) | 2008-02-26 | 2014-08-26 | Jenavalve Technology Gmbh | Estent para la colocación y el anclaje de una prótesis valvular en un sitio de implantación en el corazón de un paciente |
US8465540B2 (en) | 2008-02-26 | 2013-06-18 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis |
US8968393B2 (en) | 2008-02-28 | 2015-03-03 | Medtronic, Inc. | System and method for percutaneous mitral valve repair |
US20090264989A1 (en) | 2008-02-28 | 2009-10-22 | Philipp Bonhoeffer | Prosthetic heart valve systems |
AU2009219005B2 (en) | 2008-02-29 | 2013-07-11 | Edwards Lifesciences Corporation | Expandable member for deploying a prosthetic device |
DE102008012438B4 (de) | 2008-02-29 | 2014-12-24 | Nvt Ag | Mechanische Aortenklappe für die endovaskuläre Implantation |
DE102008012113A1 (de) | 2008-03-02 | 2009-09-03 | Transcatheter Technologies Gmbh | Stent, welcher vom expandierten Zustand erneut im Durchmesser kontrolliert verringerbar ist |
US8177836B2 (en) | 2008-03-10 | 2012-05-15 | Medtronic, Inc. | Apparatus and methods for minimally invasive valve repair |
US8313525B2 (en) | 2008-03-18 | 2012-11-20 | Medtronic Ventor Technologies, Ltd. | Valve suturing and implantation procedures |
US8377116B2 (en) | 2008-03-20 | 2013-02-19 | Abbott Cardiovascular Systems Inc. | Implantable medical device coatings with improved mechanical stability |
DE102008015781B4 (de) | 2008-03-26 | 2011-09-29 | Malte Neuss | Vorrichtung zum Verschluss von Defekten im Gefäßsystem |
ES2366266T5 (es) | 2008-03-27 | 2018-06-25 | Genomnia S.R.L. | Prótesis de válvula para implantación en conductos corporales |
US7815673B2 (en) | 2008-04-01 | 2010-10-19 | Medtronic Vascular, Inc. | Double-walled stent system |
US8430927B2 (en) | 2008-04-08 | 2013-04-30 | Medtronic, Inc. | Multiple orifice implantable heart valve and methods of implantation |
JP5734178B2 (ja) | 2008-04-09 | 2015-06-10 | ジョージア テック リサーチ コーポレイション | 心臓弁を修復するための弁形成リングおよび方法 |
WO2009140007A2 (en) | 2008-04-14 | 2009-11-19 | Ats Medical, Inc. | Tool for implantation of replacement heart valve |
US8262725B2 (en) | 2008-04-16 | 2012-09-11 | Cardiovascular Technologies, Llc | Transvalvular intraannular band for valve repair |
FR2930137B1 (fr) | 2008-04-18 | 2010-04-23 | Corevalve Inc | Materiel de traitement d'une valve cardiaque, en particulier d'une valve mitrale. |
CA2722233C (en) | 2008-04-21 | 2017-12-05 | Simcha Milo | Surgical stapling systems |
US8323336B2 (en) | 2008-04-23 | 2012-12-04 | Medtronic, Inc. | Prosthetic heart valve devices and methods of valve replacement |
US8312825B2 (en) | 2008-04-23 | 2012-11-20 | Medtronic, Inc. | Methods and apparatuses for assembly of a pericardial prosthetic heart valve |
EP3967274B1 (en) | 2008-04-23 | 2022-08-24 | Medtronic, Inc. | Stented heart valve devices |
US8136218B2 (en) | 2008-04-29 | 2012-03-20 | Medtronic, Inc. | Prosthetic heart valve, prosthetic heart valve assembly and method for making same |
US20090276040A1 (en) | 2008-05-01 | 2009-11-05 | Edwards Lifesciences Corporation | Device and method for replacing mitral valve |
JP5390597B2 (ja) | 2008-05-09 | 2014-01-15 | エドワーズ ライフサイエンシーズ コーポレイション | 変性弁膜症に特有の弁形成リング |
US9061119B2 (en) | 2008-05-09 | 2015-06-23 | Edwards Lifesciences Corporation | Low profile delivery system for transcatheter heart valve |
US8152844B2 (en) | 2008-05-09 | 2012-04-10 | Edwards Lifesciences Corporation | Quick-release annuloplasty ring holder |
US20090287303A1 (en) | 2008-05-13 | 2009-11-19 | Edwards Lifesciences Corporation | Physiologically harmonized tricuspid annuloplasty ring |
US8668668B2 (en) | 2008-05-14 | 2014-03-11 | Onset Medical Corporation | Expandable iliac sheath and method of use |
US8840661B2 (en) | 2008-05-16 | 2014-09-23 | Sorin Group Italia S.R.L. | Atraumatic prosthetic heart valve prosthesis |
GB0809357D0 (en) | 2008-05-22 | 2008-07-02 | Punjabi Prakash | Heart valve repair device |
US8202529B2 (en) | 2008-05-30 | 2012-06-19 | Abbott Cardiovascular Systems Inc. | Implantable drug delivery devices having alternating hydrophilic and amphiphilic polymer layers |
EP2293740B1 (en) | 2008-06-05 | 2014-08-13 | Medtronic, Inc. | Connection systems for two piece prosthetic heart valve assemblies and methods for making and using them |
ES2645920T3 (es) | 2008-06-06 | 2017-12-11 | Edwards Lifesciences Corporation | Válvula cardíaca transcatéter de perfil bajo |
US20110160836A1 (en) | 2008-06-20 | 2011-06-30 | Vysera Biomedical Limited | Valve device |
ES2659081T3 (es) | 2008-06-20 | 2018-03-13 | Coloplast A/S | Un biomaterial |
US8206635B2 (en) | 2008-06-20 | 2012-06-26 | Amaranth Medical Pte. | Stent fabrication via tubular casting processes |
CA3030661C (en) | 2008-06-20 | 2021-02-23 | Coloplast A/S | A valve |
US8323335B2 (en) | 2008-06-20 | 2012-12-04 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves and methods for using |
WO2010008451A2 (en) | 2008-06-23 | 2010-01-21 | Lumen Biomedical, Inc. | Embolic protection during percutaneous heart valve replacement and similar procedures |
EP3025681B1 (en) | 2008-07-15 | 2017-02-01 | St. Jude Medical, Inc. | Collabsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications |
US9226820B2 (en) | 2008-07-15 | 2016-01-05 | St. Jude Medical, Inc. | Axially anchoring collapsible and re-expandable prosthetic heart valves for various disease states |
EP2309949B1 (en) | 2008-07-17 | 2013-07-03 | Nvt Ag | Cardiac valve prosthesis system |
US8685080B2 (en) | 2008-07-21 | 2014-04-01 | Jenesis Surgical, Llc | Repositionable endoluminal support structure and its applications |
RU2373900C1 (ru) | 2008-07-23 | 2009-11-27 | Закрытое Акционерное Общество Научно-Производственное Предприятие "Мединж" | Протез клапана сердца |
US9232992B2 (en) | 2008-07-24 | 2016-01-12 | Aga Medical Corporation | Multi-layered medical device for treating a target site and associated method |
ES2659322T3 (es) | 2008-07-27 | 2018-03-14 | Pi-R-Squared Ltd. | Fracturación de calcificaciones en válvulas cardíacas |
BRPI0916696A2 (pt) | 2008-07-29 | 2015-11-17 | St Jude Medical Cardiology Div | método e sistema para ajuste a longo prazo de um dispositivo de implante |
US8337390B2 (en) | 2008-07-30 | 2012-12-25 | Cube S.R.L. | Intracardiac device for restoring the functional elasticity of the cardiac structures, holding tool for the intracardiac device, and method for implantation of the intracardiac device in the heart |
JP2012500074A (ja) | 2008-08-19 | 2012-01-05 | ディーエスエム アイピー アセッツ ビー.ブイ. | 植込み型弁プロテーゼ及びかかる弁の製造方法 |
US8652202B2 (en) | 2008-08-22 | 2014-02-18 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
CA2735091C (en) | 2008-08-25 | 2016-02-23 | Cardiokinetix, Inc. | Retrievable cardiac devices |
WO2010030882A1 (en) | 2008-09-11 | 2010-03-18 | Acist Medical Systems, Inc. | Physiological sensor delivery device and method |
WO2010031082A2 (en) | 2008-09-15 | 2010-03-18 | Arbor Surgical Technologies, Inc. | Tools, systems, and methods for remodeling tissue |
WO2010031060A1 (en) | 2008-09-15 | 2010-03-18 | Medtronic Ventor Technologies Ltd. | Prosthetic heart valve having identifiers for aiding in radiographic positioning |
US8721714B2 (en) | 2008-09-17 | 2014-05-13 | Medtronic Corevalve Llc | Delivery system for deployment of medical devices |
US9314335B2 (en) | 2008-09-19 | 2016-04-19 | Edwards Lifesciences Corporation | Prosthetic heart valve configured to receive a percutaneous prosthetic heart valve implantation |
US8287591B2 (en) | 2008-09-19 | 2012-10-16 | Edwards Lifesciences Corporation | Transformable annuloplasty ring configured to receive a percutaneous prosthetic heart valve implantation |
EP2344075B1 (en) | 2008-09-19 | 2018-12-05 | Edwards Lifesciences Corporation | Annuloplasty ring configured to receive a percutaneous prosthetic heart valve implantation |
EP4218675A3 (en) | 2008-09-19 | 2023-08-30 | Edwards Lifesciences Corporation | Prosthetic heart valve configured to receive a percutaneous prosthetic heart valve implantation |
EP2367505B1 (en) | 2008-09-29 | 2020-08-12 | Edwards Lifesciences CardiAQ LLC | Heart valve |
EP2341871B1 (en) | 2008-10-01 | 2017-03-22 | Edwards Lifesciences CardiAQ LLC | Delivery system for vascular implant |
NL1036038C (en) | 2008-10-09 | 2010-04-14 | Univ Eindhoven Tech | Multilayer preform obtained by electro-spinning, method for producing a preform as well as use thereof. |
US8702782B2 (en) | 2008-10-09 | 2014-04-22 | Strait Access Technologies Holdings (Pty) Limited | Stent deployment device |
AU2009302944A1 (en) | 2008-10-10 | 2010-04-15 | Milux Holding Sa | An improved artifical valve |
JP5607639B2 (ja) | 2008-10-10 | 2014-10-15 | サドラ メディカル インコーポレイテッド | 医療用デバイス・システム |
US8790387B2 (en) | 2008-10-10 | 2014-07-29 | Edwards Lifesciences Corporation | Expandable sheath for introducing an endovascular delivery device into a body |
US8690936B2 (en) | 2008-10-10 | 2014-04-08 | Edwards Lifesciences Corporation | Expandable sheath for introducing an endovascular delivery device into a body |
US9750592B2 (en) | 2008-10-10 | 2017-09-05 | Carsten Nils Gutt | Arrangement for implanting and method for implanting |
EP2349096B1 (en) | 2008-10-10 | 2021-01-27 | MedicalTree Patent Ltd. | An improved artificial valve |
US8137398B2 (en) | 2008-10-13 | 2012-03-20 | Medtronic Ventor Technologies Ltd | Prosthetic valve having tapered tip when compressed for delivery |
US8449625B2 (en) | 2009-10-27 | 2013-05-28 | Edwards Lifesciences Corporation | Methods of measuring heart valve annuluses for valve replacement |
US8986361B2 (en) | 2008-10-17 | 2015-03-24 | Medtronic Corevalve, Inc. | Delivery system for deployment of medical devices |
JP5539368B2 (ja) | 2008-10-20 | 2014-07-02 | コーアシスト・カーデイオバスキユラー・リミテツド | 心室機能補助デバイス及びそれを移植するための方法及び装置 |
US9119715B2 (en) | 2008-10-30 | 2015-09-01 | St. Jude Medical, Inc. | Collapsible/expandable prosthetic heart valve delivery system and methods |
US20100114305A1 (en) | 2008-10-30 | 2010-05-06 | Wei-Chang Kang | Implantable Valvular Prosthesis |
US9682242B2 (en) | 2008-11-14 | 2017-06-20 | Bal Seal Engineering, Inc. | Connector with low lead insertion force and method of reducing same |
WO2010057262A1 (en) | 2008-11-21 | 2010-05-27 | Percutaneous Cardiovascular Solutions Pty Limited | Heart valve prosthesis and method |
EP2370138B1 (en) | 2008-11-25 | 2020-12-30 | Edwards Lifesciences Corporation | Apparatus for in situ expansion of prosthetic device |
EP2385809B1 (en) | 2008-12-04 | 2016-08-31 | Georgia Tech Research Corporation | Apparatus for minimally invasive heart valve procedures |
US8591573B2 (en) | 2008-12-08 | 2013-11-26 | Hector Daniel Barone | Prosthetic valve for intraluminal implantation |
WO2010067300A1 (en) | 2008-12-12 | 2010-06-17 | Koninklijke Philips Electronics N. V. | Automatic road mapping for heart valve replacement |
US8177802B2 (en) | 2008-12-16 | 2012-05-15 | Medtronic Vascular, Inc. | Apparatus for percutaneously creating native tissue venous valves |
EP2358302B1 (en) | 2008-12-18 | 2012-12-05 | Cook Medical Technologies LLC | Stents and stent grafts |
US8308798B2 (en) | 2008-12-19 | 2012-11-13 | Edwards Lifesciences Corporation | Quick-connect prosthetic heart valve and methods |
WO2010071810A1 (en) | 2008-12-19 | 2010-06-24 | Andy Christopher Kiser | Methods and devices for endoscopic access to the heart |
US8158187B2 (en) | 2008-12-19 | 2012-04-17 | Medtronic Vascular, Inc. | Dry diazeniumdiolation methods for producing nitric oxide releasing medical devices |
CN102341063B (zh) | 2008-12-22 | 2015-11-25 | 瓦尔泰克卡迪欧有限公司 | 可调瓣环成形装置及其调节机构 |
US8911494B2 (en) | 2009-05-04 | 2014-12-16 | Valtech Cardio, Ltd. | Deployment techniques for annuloplasty ring |
US8808368B2 (en) | 2008-12-22 | 2014-08-19 | Valtech Cardio, Ltd. | Implantation of repair chords in the heart |
ES2551694T3 (es) | 2008-12-23 | 2015-11-23 | Sorin Group Italia S.R.L. | Válvula protésica expansible dotada de apéndices de anclaje |
EP2381895B1 (en) | 2008-12-31 | 2021-07-07 | Medtronic, Inc. | Semi-rigid annuloplasty ring and band and method of making an annuloplasty ring |
WO2010078603A2 (en) | 2009-01-02 | 2010-07-08 | Deep Vein Medical, Inc. | Device for regulating blood flow |
WO2010080884A1 (en) | 2009-01-07 | 2010-07-15 | Cook Incorporated | Implantable valve prosthesis with independent frame elements |
AU325341S (en) | 2009-01-08 | 2009-03-25 | Kk Kyoto Iryo Sekkei | Stent |
AU325342S (en) | 2009-01-08 | 2009-03-25 | Kk Kyoto Iryo Sekkei | Stent |
US8998982B2 (en) | 2009-01-12 | 2015-04-07 | Valve Medical Ltd. | Method and apparatus for fine adjustment of a percutaneous valve structure |
US9681950B2 (en) | 2009-01-12 | 2017-06-20 | Valve Medical Ltd. | System and method for placing a percutaneous valve device |
US9402720B2 (en) | 2009-01-12 | 2016-08-02 | Valve Medical Ltd. | Modular percutaneous valve structure and delivery method |
US9204965B2 (en) | 2009-01-14 | 2015-12-08 | Lc Therapeutics, Inc. | Synthetic chord |
WO2010085649A1 (en) | 2009-01-22 | 2010-07-29 | St. Jude Medical | Post-operative adjustment tool, minimally invasive attachment apparatus, and adjustable tricuspid ring |
JP2012515625A (ja) | 2009-01-22 | 2012-07-12 | セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド | 移植可能な装置の長期的な調整のための磁気的ドッキングシステムおよび方法 |
EP2393449B1 (en) | 2009-02-06 | 2016-09-07 | St. Jude Medical, Inc. | Support for adjustable annuloplasty ring |
JP5662353B2 (ja) | 2009-02-06 | 2015-01-28 | セント・ジュード・メディカル,インコーポレイテッド | 心臓弁輪サイザー |
EP2393442A4 (en) | 2009-02-09 | 2017-08-09 | St. Jude Medical, Cardiology Division, Inc. | Inflatable minimally invasive system for delivering and securing an annular implant |
WO2010091653A1 (de) | 2009-02-11 | 2010-08-19 | Georg Lutter | Katheter |
US20120010636A1 (en) | 2009-02-11 | 2012-01-12 | Nanyang Technological University | Multi-layered surgical prosthesis |
GB0902339D0 (en) | 2009-02-12 | 2009-04-01 | St Georges Healthcare Nhs Trus | Percutaneous guidewire |
DE102009009158B4 (de) | 2009-02-16 | 2010-11-04 | Siemens Aktiengesellschaft | Lokalisierung eines medizinischen Instruments in einem präinvasiv aufgenommenen Tomographie-Bilddatensatz |
EP2398421B1 (en) | 2009-02-20 | 2017-09-27 | St. Jude Medical, Inc. | Devices and methods for collapsing prosthetic heart valves |
EP3610833B1 (en) | 2009-02-24 | 2024-05-29 | Cook Medical Technologies LLC | Low profile support frame |
US8348997B2 (en) | 2009-02-24 | 2013-01-08 | Medtronic Vascular, Inc. | One-way replacement valve |
EP2400923B1 (en) | 2009-02-25 | 2017-01-04 | JenaValve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US20100217382A1 (en) | 2009-02-25 | 2010-08-26 | Edwards Lifesciences | Mitral valve replacement with atrial anchoring |
US8740930B2 (en) | 2009-02-25 | 2014-06-03 | Medtronic Vascular, Inc. | Embolic filter device independent of treatment device |
EP2400924B1 (en) | 2009-02-27 | 2017-06-28 | St. Jude Medical, Inc. | Prosthetic heart valve |
US8021420B2 (en) | 2009-03-12 | 2011-09-20 | Medtronic Vascular, Inc. | Prosthetic valve delivery system |
USD635262S1 (en) | 2009-03-12 | 2011-03-29 | Biocore Biotechnologia S/A | Stent |
USD635261S1 (en) | 2009-03-12 | 2011-03-29 | Biocore Biotechnologia S/A | Stent |
US20100233266A1 (en) | 2009-03-13 | 2010-09-16 | Cleek Robert L | Articles and methods of treating vascular conditions |
CA2759242A1 (en) | 2009-03-17 | 2010-09-23 | Mitrassist Medical Ltd. | Heart valve prosthesis with collapsible valve and method of delivery thereof |
US8715207B2 (en) | 2009-03-19 | 2014-05-06 | Sorin Group Italia S.R.L. | Universal valve annulus sizing device |
RU2393818C1 (ru) | 2009-03-19 | 2010-07-10 | Закрытое Акционерное Общество Научно-Производственное Предприятие "Мединж" | Реимплантируемый протез клапана сердца и инструмент для его установки |
ES2543460T3 (es) | 2009-03-26 | 2015-08-19 | Sorin Group Usa, Inc. | Dispositivos de dimensionamiento de anuloplastia para intervenciones mínimamente invasivas |
CN101919753A (zh) | 2009-03-30 | 2010-12-22 | 卡迪万蒂奇医药公司 | 人工主动脉瓣膜或二尖瓣膜的无缝合移植方法和装置 |
GB0905444D0 (en) | 2009-03-30 | 2009-05-13 | Ucl Business Plc | Heart valve prosthesis |
US9980818B2 (en) | 2009-03-31 | 2018-05-29 | Edwards Lifesciences Corporation | Prosthetic heart valve system with positioning markers |
US20100256723A1 (en) | 2009-04-03 | 2010-10-07 | Medtronic Vascular, Inc. | Prosthetic Valve With Device for Restricting Expansion |
EP2416739B1 (en) | 2009-04-10 | 2016-06-08 | Lon Sutherland Annest | An implantable scaffolding containing an orifice for use with a prosthetic or bio-prosthetic valve |
CA2758067A1 (en) | 2009-04-10 | 2010-10-14 | Cardiokinetix, Inc. | Sealing and filling ventricular partitioning devices to improve cardiac function |
US20100262157A1 (en) | 2009-04-14 | 2010-10-14 | Medtronic Vascular, Inc. | Methods and Systems for Loading a Stent |
US9968358B2 (en) | 2009-04-15 | 2018-05-15 | Microvention, Inc. | Implant delivery system |
EP2810620B1 (en) | 2009-04-15 | 2022-09-14 | Edwards Lifesciences CardiAQ LLC | Vascular implant and delivery system |
US8500688B2 (en) | 2009-04-16 | 2013-08-06 | Medtronic, Inc. | Retrograde coronary sinus perfusion cannula and methods of using same |
US8500801B2 (en) | 2009-04-21 | 2013-08-06 | Medtronic, Inc. | Stents for prosthetic heart valves and methods of making same |
US8734484B2 (en) | 2009-04-21 | 2014-05-27 | Medtronic, Inc. | System and method for closure of an internal opening in tissue, such as a trans-apical access opening |
US9011524B2 (en) | 2009-04-24 | 2015-04-21 | Medtronic, Inc. | Prosthetic heart valves and methods of attaching same |
US8876883B2 (en) | 2009-04-24 | 2014-11-04 | Medtronic Vascular, Inc. | Self-flaring active fixation element for a stent graft |
EP2246011B1 (en) | 2009-04-27 | 2014-09-03 | Sorin Group Italia S.r.l. | Prosthetic vascular conduit |
CA2778129C (en) | 2009-04-28 | 2014-09-02 | Dc Devices, Inc. | Devices, systems and methods to treat heart failure |
EP2424428B1 (en) | 2009-04-29 | 2015-03-04 | St. Jude Medical AB | Implantable coronary perfusion monitoring device |
AU2010241596B2 (en) | 2009-04-29 | 2013-10-24 | The Cleveland Clinic Foundation | Apparatus and method for replacing a diseased cardiac valve |
US9034034B2 (en) | 2010-12-22 | 2015-05-19 | V-Wave Ltd. | Devices for reducing left atrial pressure, and methods of making and using same |
WO2010128501A1 (en) | 2009-05-04 | 2010-11-11 | V-Wave Ltd. | Device and method for regulating pressure in a heart chamber |
US8523881B2 (en) | 2010-07-26 | 2013-09-03 | Valtech Cardio, Ltd. | Multiple anchor delivery tool |
RU2542378C2 (ru) | 2009-05-08 | 2015-02-20 | Конинклейке Филипс Электроникс Н.В. | Ультразвуковое планирование и наведение имплантируемых медицинских устройств |
US8403982B2 (en) | 2009-05-13 | 2013-03-26 | Sorin Group Italia S.R.L. | Device for the in situ delivery of heart valves |
US8353953B2 (en) | 2009-05-13 | 2013-01-15 | Sorin Biomedica Cardio, S.R.L. | Device for the in situ delivery of heart valves |
EP2250976B1 (en) | 2009-05-13 | 2015-08-26 | Sorin Group Italia S.r.l. | Device for the in situ delivery of heart valves |
EP2250970B1 (en) | 2009-05-13 | 2012-12-26 | Sorin Biomedica Cardio S.r.l. | Device for surgical interventions |
FR2945440B1 (fr) | 2009-05-14 | 2012-12-07 | Perouse Lab | Dispositif de traitement et necessaire de traitement d'un conduit de circulation du sang |
US8449466B2 (en) | 2009-05-28 | 2013-05-28 | Edwards Lifesciences Corporation | System and method for locating medical devices in vivo using ultrasound Doppler mode |
US8075611B2 (en) | 2009-06-02 | 2011-12-13 | Medtronic, Inc. | Stented prosthetic heart valves |
DE102009024648B4 (de) | 2009-06-03 | 2018-05-09 | Aesculap Ag | Markierte Venen-Ummantelung, insbesondere zur Wiederherstellung der Venenklappenfunktion variköser Venen |
US8348998B2 (en) | 2009-06-26 | 2013-01-08 | Edwards Lifesciences Corporation | Unitary quick connect prosthetic heart valve and deployment system and methods |
CA2767035C (en) | 2009-07-02 | 2015-07-21 | The Cleveland Clinic Foundation | Apparatus and method for replacing a diseased cardiac valve |
FR2947716B1 (fr) | 2009-07-10 | 2011-09-02 | Cormove | Implant prothetique ameliore |
ES2653948T3 (es) | 2009-07-14 | 2018-02-09 | Edwards Lifesciences Corporation | Sistema de colocación transapical de válvulas cardíacas |
US8439970B2 (en) | 2009-07-14 | 2013-05-14 | Edwards Lifesciences Corporation | Transapical delivery system for heart valves |
EP2453942B1 (en) | 2009-07-15 | 2014-08-13 | Technical University of Denmark | Polymer coating comprising 2-methoxyethyl acrylate units synthesized by surface-initiated atom transfer radical polymerization |
EP2453843B1 (en) | 2009-07-17 | 2015-09-30 | Kirk Promotion LTD. | Artificial valve for implantation |
US8821570B2 (en) | 2009-07-20 | 2014-09-02 | Micardia Corporation | Adjustable annuloplasty ring with subcutaneous activation port |
US8119704B2 (en) | 2009-07-21 | 2012-02-21 | Abbott Cardiovascular Systems Inc. | Implantable medical device comprising copolymer of L-lactide with improved fracture toughness |
EP2456483B1 (en) | 2009-07-22 | 2017-11-01 | The Texas A&M University System | Diastolic recoil device for treatment of cardiac pathologies |
US20110022165A1 (en) | 2009-07-23 | 2011-01-27 | Edwards Lifesciences Corporation | Introducer for prosthetic heart valve |
EP2459127B1 (en) | 2009-07-27 | 2015-09-23 | Endologix, Inc. | Stent graft |
US8500757B2 (en) | 2009-07-28 | 2013-08-06 | Edwards Lifesciences Corporation | Surgical puncture cinch and closure system |
US8876712B2 (en) | 2009-07-29 | 2014-11-04 | Edwards Lifesciences Corporation | Intracardiac sheath stabilizer |
EP2467104B1 (en) | 2009-08-20 | 2016-11-02 | Cook Medical Technologies LLC | Loading apparatus and system for expandable intraluminal medical devices |
EP3524256A1 (en) | 2009-08-24 | 2019-08-14 | Stealth Peptides International, Inc. | Methods and copositions for preventing or treating opthalmic conditions |
US8414645B2 (en) | 2009-08-27 | 2013-04-09 | Medtronic, Inc. | Transcatheter valve delivery systems and methods |
JP5866668B2 (ja) | 2009-08-28 | 2016-02-17 | メドトロニック 3エフ セラピュティックス インコーポレイテッド | クリンプ装置及び使用方法 |
US8545742B2 (en) | 2009-08-28 | 2013-10-01 | Abbott Cardiovascular Systems Inc. | Method of fabricating a low crystallinity poly(L-lactide) tube |
JP5906553B2 (ja) | 2009-08-28 | 2016-04-20 | メドトロニック 3エフ セラピュティックス インコーポレイテッド | 外科的搬送装置及び使用方法 |
JP5665149B2 (ja) | 2009-08-28 | 2015-02-04 | メドトロニック 3エフ セラピュティックス インコーポレイテッド | 経心尖搬送装置及び使用方法 |
US9757107B2 (en) | 2009-09-04 | 2017-09-12 | Corvia Medical, Inc. | Methods and devices for intra-atrial shunts having adjustable sizes |
WO2011031733A2 (en) | 2009-09-09 | 2011-03-17 | The Cleveland Clinic Foundation | Apparatus and method for delivering an implantable medical device to a diseased cardiac valve |
AU2010292118B9 (en) | 2009-09-11 | 2014-01-09 | Gi Dynamics, Inc. | Anchors with open heads |
EP3042615A1 (en) | 2009-09-15 | 2016-07-13 | Evalve, Inc. | Methods, systems and devices for cardiac valve repair |
WO2011035154A1 (en) | 2009-09-18 | 2011-03-24 | The Regents Of The University Of California | Endovascular prosthetic heart valve replacement |
AU2010295291B2 (en) | 2009-09-21 | 2013-10-24 | Medtronic Inc. | Stented transcatheter prosthetic heart valve delivery system and method |
WO2011038353A2 (en) | 2009-09-28 | 2011-03-31 | Ryan Timothy J | Charged grafts and methods for using them |
US9730790B2 (en) | 2009-09-29 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Replacement valve and method |
WO2011041571A2 (en) | 2009-10-01 | 2011-04-07 | Kardium Inc. | Medical device, kit and method for constricting tissue or a bodily orifice, for example, a mitral valve |
CA2777067A1 (en) | 2009-10-14 | 2011-04-21 | Cardiovascular Technologies, Llc | Percutaneous transvalvular intraannular band for mitral valve repair |
FR2951549B1 (fr) | 2009-10-15 | 2013-08-23 | Olivier Schussler | Procede d'obtention de bioprotheses medicales implantables |
CA2777495A1 (en) | 2009-10-26 | 2011-05-12 | Cardiokinetix, Inc. | Ventricular volume reduction |
US8277502B2 (en) | 2009-10-29 | 2012-10-02 | Valtech Cardio, Ltd. | Tissue anchor for annuloplasty device |
CN105167886B (zh) | 2009-11-02 | 2017-11-07 | 西美蒂斯股份公司 | 主动脉生物假体及用于其递送的系统 |
WO2011057087A1 (en) | 2009-11-05 | 2011-05-12 | The Trustees University Of Pennsylvania | Valve prosthesis |
GR1007028B (el) | 2009-11-11 | 2010-10-22 | Ευσταθιος-Ανδρεας Αγαθος | Υποστηρικτης βιοπροσθετικων βαλβιδων με διαγλωχινικο συνδεσμο σχηματος καρδιας |
DE102009055969A1 (de) | 2009-11-27 | 2011-06-01 | Transcatheter Technologies Gmbh | Vorrichtung und Set zum Falten oder Entfalten eines medizinischen Implantats und Verfahren |
US8734467B2 (en) | 2009-12-02 | 2014-05-27 | Valtech Cardio, Ltd. | Delivery tool for implantation of spool assembly coupled to a helical anchor |
AU2010328106A1 (en) | 2009-12-08 | 2012-07-05 | Avalon Medical Ltd. | Device and system for transcatheter mitral valve replacement |
CN102858272B (zh) | 2009-12-15 | 2015-07-15 | 爱德华兹生命科学公司 | 治疗脉管通道的膨胀设备 |
DK2513200T3 (en) | 2009-12-18 | 2018-06-14 | Coloplast As | A biomaterial |
US8869982B2 (en) | 2009-12-18 | 2014-10-28 | Edwards Lifesciences Corporation | Prosthetic heart valve packaging and deployment system |
US20110146361A1 (en) | 2009-12-22 | 2011-06-23 | Edwards Lifesciences Corporation | Method of Peening Metal Heart Valve Stents |
DE102009060228B4 (de) | 2009-12-23 | 2014-12-04 | Acandis Gmbh & Co. Kg | Medizinische Vorrichtungen |
CN102113921A (zh) | 2009-12-30 | 2011-07-06 | 微创医疗器械(上海)有限公司 | 一种介入式心脏瓣膜 |
US20110160838A1 (en) | 2009-12-31 | 2011-06-30 | Blanzy Jeffrey S | Endoprosthesis containing multi-phase ferrous steel |
US9504562B2 (en) | 2010-01-12 | 2016-11-29 | Valve Medical Ltd. | Self-assembling modular percutaneous valve and methods of folding, assembly and delivery |
US8449608B2 (en) | 2010-01-22 | 2013-05-28 | Edwards Lifesciences Corporation | Tricuspid ring |
EP2351540A1 (en) | 2010-01-27 | 2011-08-03 | Jönsson, Anders | Device and method for reducing cardiac valve regurgitation |
US10932907B2 (en) | 2010-02-03 | 2021-03-02 | Medtronic, Inc. | Semi-flexible annuloplasty ring |
US20110190697A1 (en) | 2010-02-03 | 2011-08-04 | Circulite, Inc. | Vascular introducers having an expandable section |
US9107749B2 (en) | 2010-02-03 | 2015-08-18 | Edwards Lifesciences Corporation | Methods for treating a heart |
US8839957B2 (en) | 2010-02-15 | 2014-09-23 | Michael C. Murad | Prosthetic heart valve packaging system |
DE102010008360A1 (de) | 2010-02-17 | 2011-09-29 | Transcatheter Technologies Gmbh | Medizinisches Implantat, in welchem beim Crimpen bzw. Falten Lücken verbleiben, Verfahren und Einrichtung zum Verbringen |
US8926693B2 (en) | 2010-02-17 | 2015-01-06 | Medtronic, Inc. | Heart valve delivery catheter with safety button |
US8292948B2 (en) | 2010-02-17 | 2012-10-23 | Medtronic Vascular, Inc. | Apparatus and methods for creating a venous valve from autologous tissue |
US8518106B2 (en) | 2010-02-17 | 2013-08-27 | Medtronic, Inc. | Catheter assembly with valve crimping accessories |
DE102010008382A1 (de) | 2010-02-17 | 2011-08-18 | Transcatheter Technologies GmbH, 93053 | Verfahren zum Crimpen bzw. Falten eines medizinischen Implantats an einer Einrichtung zum Verbringen oder Einführen desselben unter Einsatz von Zero-Pressure-Crimping sowie Einrichtungen |
DE102010008362A1 (de) | 2010-02-17 | 2011-08-18 | Transcatheter Technologies GmbH, 93053 | Medizinisches Implantat, welches aus einem nicht expandierten Zustand expandierbar ist |
DE102010008338A1 (de) | 2010-02-17 | 2011-08-18 | Transcatheter Technologies GmbH, 93053 | Einrichtung, vorgesehen, um an einem Katheter befestigt oder mit diesem verbunden zu werden, Katheter und Verfahren |
US8475523B2 (en) | 2010-02-17 | 2013-07-02 | Medtronic, Inc. | Distal tip assembly for a heart valve delivery catheter |
US20110208293A1 (en) | 2010-02-23 | 2011-08-25 | Medtronic, Inc. | Catheter-Based Heart Valve Therapy System with Sizing Balloon |
US9226826B2 (en) | 2010-02-24 | 2016-01-05 | Medtronic, Inc. | Transcatheter valve structure and methods for valve delivery |
US9414914B2 (en) | 2010-02-24 | 2016-08-16 | Medtronic Ventor Technologies Ltd. | Catheter assembly with valve crimping accessories |
EP2538878B1 (en) | 2010-02-25 | 2021-11-24 | JenaValve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
SG186837A1 (en) | 2010-03-01 | 2013-02-28 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve and methods associated therewith |
US8679404B2 (en) | 2010-03-05 | 2014-03-25 | Edwards Lifesciences Corporation | Dry prosthetic heart valve packaging system |
US8795354B2 (en) | 2010-03-05 | 2014-08-05 | Edwards Lifesciences Corporation | Low-profile heart valve and delivery system |
ES2922283T3 (es) | 2010-03-05 | 2022-09-12 | Edwards Lifesciences Corp | Mecanismos de retención para válvulas protésicas |
US20110224785A1 (en) | 2010-03-10 | 2011-09-15 | Hacohen Gil | Prosthetic mitral valve with tissue anchors |
ES2365317B1 (es) | 2010-03-19 | 2012-08-03 | Xavier Ruyra Baliarda | Banda protésica, en particular para la reparación de una válvula mitral. |
BR112012023769B1 (pt) | 2010-03-23 | 2020-11-10 | Edwards Lifesciences Corporation | método para preparar material de membrana de tecido bioprotético |
CN102892382B (zh) | 2010-03-23 | 2015-09-02 | 波士顿科技西姆德股份有限公司 | 瓣环成形术装置 |
DE102010012677B4 (de) | 2010-03-24 | 2017-08-10 | Fehling Instruments Gmbh & Co. Kg | Spreizer für die Aortenklappenrekonstruktion |
SE535140C2 (sv) | 2010-03-25 | 2012-04-24 | Jan Otto Solem | En implanterbar anordning, kit och system för förbättring av hjärtfunktionen, innefattande medel för generering av longitudinell rörelse av mitralisklaffen |
US9480557B2 (en) | 2010-03-25 | 2016-11-01 | Medtronic, Inc. | Stents for prosthetic heart valves |
SE535690C2 (sv) | 2010-03-25 | 2012-11-13 | Jan Otto Solem | En implanterbar anordning och kit för hjärtunderstöd, innefattande medel för generering av longitudinell rörelse av mitralisklaffen |
EP2552356B1 (en) | 2010-03-26 | 2019-03-13 | Thubrikar Aortic Valve Inc. | Valve component, frame component and prosthetic valve device including the same for implantation in a body lumen |
US9320597B2 (en) | 2010-03-30 | 2016-04-26 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery system with recapturing feature and method |
US8491650B2 (en) | 2010-04-08 | 2013-07-23 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery system and method with stretchable stability tube |
US8998980B2 (en) | 2010-04-09 | 2015-04-07 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery system with recapturing feature and method |
US8512400B2 (en) | 2010-04-09 | 2013-08-20 | Medtronic, Inc. | Transcatheter heart valve delivery system with reduced area moment of inertia |
US8512401B2 (en) | 2010-04-12 | 2013-08-20 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery system with funnel recapturing feature and method |
US8579963B2 (en) | 2010-04-13 | 2013-11-12 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery device with stability tube and method |
US8357195B2 (en) | 2010-04-15 | 2013-01-22 | Medtronic, Inc. | Catheter based annuloplasty system and method |
US9833314B2 (en) | 2010-04-16 | 2017-12-05 | Abiomed, Inc. | Percutaneous valve deployment |
US10512537B2 (en) | 2010-04-16 | 2019-12-24 | Abiomed, Inc. | Flow optimized polymeric heart valve |
US8465541B2 (en) | 2010-04-19 | 2013-06-18 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery system and method with expandable stability tube |
US8764811B2 (en) | 2010-04-20 | 2014-07-01 | Medtronic Vascular, Inc. | Controlled tip release stent graft delivery system and method |
US8876892B2 (en) | 2010-04-21 | 2014-11-04 | Medtronic, Inc. | Prosthetic heart valve delivery system with spacing |
US8623075B2 (en) | 2010-04-21 | 2014-01-07 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery system and method with controlled expansion of prosthetic heart valve |
US8740976B2 (en) | 2010-04-21 | 2014-06-03 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery system with flush report |
EP3581151B1 (en) | 2010-04-21 | 2021-03-10 | Medtronic, Inc. | Prosthetic valve with sealing members |
US8623079B2 (en) | 2010-04-23 | 2014-01-07 | Medtronic, Inc. | Stents for prosthetic heart valves |
US9629719B2 (en) | 2010-04-23 | 2017-04-25 | Medtronic, Inc. | Delivery systems and methods of implantation for prosthetic heart valves |
EP2422823B1 (en) | 2010-07-30 | 2014-03-19 | Institut Quimic De Sarria | Bioactive implant |
US8568474B2 (en) | 2010-04-26 | 2013-10-29 | Medtronic, Inc. | Transcatheter prosthetic heart valve post-dilatation remodeling devices and methods |
WO2011139746A1 (en) | 2010-04-27 | 2011-11-10 | Medtronic Inc. | Transcatheter prosthetic heart valve delivery device with passive trigger release |
US8852271B2 (en) | 2010-04-27 | 2014-10-07 | Medtronic Vascular, Inc. | Transcatheter prosthetic heart valve delivery device with biased release features |
WO2011137252A1 (en) | 2010-04-29 | 2011-11-03 | Vinay Badhwar | Automatic suturing apparatus and methods of use |
US8974475B2 (en) | 2010-04-30 | 2015-03-10 | Medtronic, Inc. | Methods and devices for cardiac valve repair or replacement |
EP3795119A1 (en) | 2010-05-10 | 2021-03-24 | Edwards Lifesciences Corporation | Prosthetic heart valve with collapsible frame and cantilevered commissure portions |
US9554901B2 (en) | 2010-05-12 | 2017-01-31 | Edwards Lifesciences Corporation | Low gradient prosthetic heart valve |
US9433501B2 (en) | 2010-05-19 | 2016-09-06 | Direct Flow Medical, Inc. | Inflation media for implants |
US10856978B2 (en) | 2010-05-20 | 2020-12-08 | Jenavalve Technology, Inc. | Catheter system |
PL2387977T3 (pl) | 2010-05-20 | 2014-05-30 | Jenavalve Tech Inc | System cewnikowania do wprowadzania rozprężalnego stentu zastawki serca do ciała pacjenta |
IT1400327B1 (it) | 2010-05-21 | 2013-05-24 | Sorin Biomedica Cardio Srl | Dispositivo di supporto per protesi valvolari e corrispondente corredo. |
US8790394B2 (en) | 2010-05-24 | 2014-07-29 | Valtech Cardio, Ltd. | Adjustable artificial chordeae tendineae with suture loops |
WO2011147849A1 (en) | 2010-05-25 | 2011-12-01 | Jenavalve Technology Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
US9387077B2 (en) | 2010-05-27 | 2016-07-12 | Medtronic Vascular Galway | Catheter assembly with prosthesis crimping and prosthesis retaining accessories |
WO2011148299A1 (en) | 2010-05-27 | 2011-12-01 | Koninklijke Philips Electronics N.V. | Determining the specific orientation of an object |
US9561102B2 (en) | 2010-06-02 | 2017-02-07 | Medtronic, Inc. | Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve |
EP3441045B1 (en) | 2010-06-07 | 2020-07-29 | Valtech Cardio, Ltd. | Apparatus to draw first and second portions of tissue toward each other |
IT1400544B1 (it) | 2010-06-09 | 2013-06-11 | Sorin Biomedica Cardio Srl | Procedimento di detossificazione di tessuto biologico. |
EP3061422B1 (en) | 2010-06-21 | 2021-11-03 | Edwards Lifesciences CardiAQ LLC | Replacement heart valve |
JP5833832B2 (ja) | 2010-06-30 | 2015-12-16 | テルモ株式会社 | 生体移植片移送器具及び生体移植片の移送方法 |
US8408214B2 (en) | 2010-07-08 | 2013-04-02 | Benjamin Spenser | Method for implanting prosthetic valve |
CN103189015B (zh) | 2010-07-09 | 2016-07-06 | 海莱夫简易股份公司 | 经导管的房室瓣假体 |
EP3552655B1 (en) | 2010-07-13 | 2020-12-23 | Loma Vista Medical, Inc. | Inflatable medical devices |
US9526483B2 (en) | 2010-07-15 | 2016-12-27 | Medtronic Vascular Galway | Apical closure system |
BR112013001024A2 (pt) | 2010-07-15 | 2016-05-24 | St Jude Medical | dispositivo de colocação para um dispositivo médico implantável, sistema para colocação de dispositivo médico implantável, e, método de colocação de válvula protética |
USD665080S1 (en) | 2010-07-16 | 2012-08-07 | Biocore Biotechnologia S/A | Coronary prosthesis |
USD665079S1 (en) | 2010-07-16 | 2012-08-07 | Biocore Biotechnologia S/A | Coronary prosthesis |
US8992604B2 (en) | 2010-07-21 | 2015-03-31 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US9132009B2 (en) | 2010-07-21 | 2015-09-15 | Mitraltech Ltd. | Guide wires with commissural anchors to advance a prosthetic valve |
US20120130468A1 (en) | 2010-07-27 | 2012-05-24 | Fred Khosravi | Methods and apparatus for treating neurovascular venous outflow obstruction |
WO2012018599A1 (en) | 2010-08-03 | 2012-02-09 | Cook Medical Technologies Llc | Two valve caval stent for functional replacement of incompetent tricuspid valve |
EP2600799B1 (en) | 2010-08-04 | 2017-05-17 | ValCare, Inc. | Percutaneous transcatheter repair of heart valves |
JP2013539381A (ja) | 2010-08-17 | 2013-10-24 | セント・ジュード・メディカル,インコーポレイテッド | 折畳み可能な心臓弁用送達システム |
AU2011292463B2 (en) | 2010-08-17 | 2014-01-23 | St. Jude Medical, Inc. | Tip for medical implant delivery system |
US10426606B2 (en) | 2010-08-23 | 2019-10-01 | Edwards Lifesciences Corporation | Color-coded prosthetic valve system and methods for using the same |
US10524911B2 (en) | 2010-08-24 | 2020-01-07 | Edwards Lifesciences Corporation | Flexible annuloplasty ring with select control points |
WO2012026965A2 (en) | 2010-08-24 | 2012-03-01 | St. Jude Medical, Inc. | Staged deployment devices and methods for transcatheter heart valve delivery systems |
US9039759B2 (en) | 2010-08-24 | 2015-05-26 | St. Jude Medical, Cardiology Division, Inc. | Repositioning of prosthetic heart valve and deployment |
EP2608815B1 (en) | 2010-08-24 | 2018-03-21 | Collagen Solutions NZ Limited | Biomaterials with enhanced properties and devices made therefrom |
BR122019025550B1 (pt) | 2010-08-31 | 2020-09-29 | Edwards Lifesciences Corporation | Anel de anuloplastia tricúspide protético |
EP2422748B1 (de) | 2010-08-31 | 2016-01-27 | Biotronik AG | Medizinisches Implantat, insbesondere Klappenimplantat, zur Implantation in einen tierischen und/oder menschlichen Körper sowie Verfahren, insbesondere Herstellungsverfahren, zur Herstellung einer Implantationsvorrichtung für das medizinische Implantat |
WO2012031141A2 (en) | 2010-09-01 | 2012-03-08 | Maurice Buchbinder | Cardiac valve support structure |
EP4052682A1 (en) | 2010-09-01 | 2022-09-07 | Medtronic Vascular Galway | Prosthetic valve support structure |
US9333075B2 (en) | 2010-09-10 | 2016-05-10 | Symetis Sa | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
US8641757B2 (en) | 2010-09-10 | 2014-02-04 | Edwards Lifesciences Corporation | Systems for rapidly deploying surgical heart valves |
DE102010037529A1 (de) | 2010-09-14 | 2012-03-15 | Transcatheter Technologies Gmbh | Einrichtung, vorgesehen, um an einem Katheter befestigt oder mit diesem verbunden zu werden, Katheter und Verfahren |
FR2964855B1 (fr) | 2010-09-17 | 2013-10-18 | Ct Hospitalier Regional Universitaire D Amiens | Implant destine a etre place dans un passage sanguin auriculo-ventriculaire |
BR112013006288A2 (pt) | 2010-09-17 | 2016-06-07 | St Jude Medical Cardiology Div | dispositivo de colocação para uma válvula cardíaca protética colapsável, e, método para colocar uma válvula cardíaca protética colapsável em um paciente |
EP2616006B1 (en) | 2010-09-17 | 2018-08-29 | St. Jude Medical, Cardiology Division, Inc. | Retainers for transcatheter heart valve delivery systems |
JP5883452B2 (ja) | 2010-09-17 | 2016-03-15 | セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド | 自己拡張型折り畳み可能心臓弁を装着するためのアセンブリ及び方法 |
ES2651744T3 (es) | 2010-09-20 | 2018-01-29 | St. Jude Medical, Cardiology Division, Inc. | Dispositivo de entrega provisto de un vástago curvado y un miembro de enderezamiento para la implantación transcatéter de una válvula aórtica |
JP2013540484A (ja) | 2010-09-20 | 2013-11-07 | セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド | 折畳み可能な人工弁における弁尖の取付装置 |
US20120078360A1 (en) | 2010-09-23 | 2012-03-29 | Nasser Rafiee | Prosthetic devices, systems and methods for replacing heart valves |
US10321998B2 (en) | 2010-09-23 | 2019-06-18 | Transmural Systems Llc | Methods and systems for delivering prostheses using rail techniques |
WO2012040655A2 (en) | 2010-09-23 | 2012-03-29 | Cardiaq Valve Technologies, Inc. | Replacement heart valves, delivery devices and methods |
JP5926265B2 (ja) | 2010-09-24 | 2016-05-25 | シメティス・ソシエテ・アノニムSymetis Sa | ステント弁、送達装置、および送達方法 |
US8845720B2 (en) | 2010-09-27 | 2014-09-30 | Edwards Lifesciences Corporation | Prosthetic heart valve frame with flexible commissures |
EP2623068B1 (en) | 2010-09-29 | 2022-03-23 | Tau-PNU Medical Co., Ltd. | Tissue protective device for coronary sinus and tricuspid valve for mitral valve cerclage |
WO2012044901A2 (en) | 2010-09-30 | 2012-04-05 | BioStable Science & Engineering, Inc. | Intra-annular mounting frame for aortic valve repair |
CA2813254A1 (en) | 2010-09-30 | 2012-04-12 | BioStable Science & Engineering, Inc. | Aortic valve devices |
RS60735B1 (sr) | 2010-10-05 | 2020-09-30 | Edwards Lifesciences Corp | Protetski srčani zalistak |
WO2012054776A1 (en) | 2010-10-21 | 2012-04-26 | Medtronic Inc | Mitral bioprosthesis with low ventricular profile |
GB201017921D0 (en) | 2010-10-22 | 2010-12-01 | Ucl Business Plc | Prothesis delivery system |
US8562663B2 (en) | 2010-10-26 | 2013-10-22 | Medtronic Ventor Technologies Ltd. | Devices and methods for loading a prosthesis onto a delivery system |
US8584849B2 (en) | 2010-10-28 | 2013-11-19 | Medtronic Ventor Technologies Ltd. | Tray for loading a medical device |
US20120116496A1 (en) | 2010-11-05 | 2012-05-10 | Chuter Timothy A | Stent structures for use with valve replacements |
US20120116498A1 (en) | 2010-11-05 | 2012-05-10 | Chuter Timothy A | Aortic valve prostheses |
IT1402571B1 (it) | 2010-11-12 | 2013-09-13 | Ht Consultant Di Giovanni Righini | Sistema protesico per valvola cardio-vascolare con struttura di ancoraggio separata |
US20120191174A1 (en) | 2010-11-16 | 2012-07-26 | Trivascular, Inc. | Advanced endovascular graft and delivery system |
DE102010051632B4 (de) | 2010-11-17 | 2013-09-12 | Hans-Hinrich Sievers | Gestentete biologische Herzklappe |
US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
EP2640316B1 (en) | 2010-11-18 | 2017-03-15 | Pavilion Medical Innovations, LLC | Tissue restraining devices and methods of use |
US8932350B2 (en) | 2010-11-30 | 2015-01-13 | Edwards Lifesciences Corporation | Reduced dehiscence annuloplasty ring |
US9078750B2 (en) | 2010-11-30 | 2015-07-14 | Edwards Lifesciences Corporation | Ergonomic mitral heart valve holders |
CA2819424C (en) | 2010-12-14 | 2020-07-21 | Transcatheter Technologies Gmbh | Apparatus comprising an aligning device, set and method |
US9579197B2 (en) | 2010-12-15 | 2017-02-28 | Medtronic Vascular, Inc. | Systems and methods for positioning a heart valve using visual markers |
DE102010061371A1 (de) | 2010-12-20 | 2012-06-21 | Transcatheter Technologies Gmbh | Vorrichtung mit individuellen Schaftfasern und Set zum Falten oder Entfalten eines medizinischen Implantats und Verfahren |
EP2468215A1 (en) | 2010-12-22 | 2012-06-27 | Centre Hospitaller Universitaire Vaudois (CHUV) | Annuloplasty ring |
WO2012141757A1 (en) | 2010-12-29 | 2012-10-18 | Neochord, Inc. | Exchangeable system for minimally invasive beating heart repair of heart valve leaflets |
US8948848B2 (en) | 2011-01-07 | 2015-02-03 | Innovative Cardiovascular Solutions, Llc | Angiography catheter |
DK2663258T3 (en) | 2011-01-11 | 2019-03-11 | Hans Reiner Figulla | PROTEST VALVE TO REPLACE AN ATRIOVENTRICULAR HEART VALVE |
US9687342B2 (en) | 2011-01-11 | 2017-06-27 | Hans Reiner Figulla | Valve prosthesis for replacing an atrioventricular valve of the heart with anchoring element |
EP2474287A1 (en) | 2011-01-11 | 2012-07-11 | Symetis Sa | Delivery catheter for stent-valve, and sub-assembly therefor |
JP6002150B2 (ja) | 2011-01-11 | 2016-10-05 | シメティス・ソシエテ・アノニムSymetis Sa | ガイドカテーテルおよびそれを含む組み合わせ |
KR102022518B1 (ko) | 2011-01-18 | 2019-09-18 | 로마 비스타 메디컬, 인코포레이티드. | 팽창 가능 의료 장치 |
DE102011009555A1 (de) | 2011-01-21 | 2012-07-26 | Aesculap Ag | Gefäßprothese mit integrierter Aortenklappe |
US8845717B2 (en) | 2011-01-28 | 2014-09-30 | Middle Park Medical, Inc. | Coaptation enhancement implant, system, and method |
WO2012106351A1 (en) | 2011-01-31 | 2012-08-09 | St. Jude Medical, Inc. | Tool for the adjustment of a prosthetic anatomical device |
EP2670353B1 (en) | 2011-01-31 | 2016-03-30 | St. Jude Medical, Inc. | Adjustment assembly for an adjustable prosthetic valve device |
EP2670356B1 (en) | 2011-01-31 | 2016-09-28 | St. Jude Medical, Inc. | Adjustable prosthetic anatomical device holder and handle for the implantation of an annuloplasty ring |
EP2670354B1 (en) | 2011-01-31 | 2016-04-27 | St. Jude Medical, Inc. | Adjustable annuloplasty ring sizing indicator |
ES2589503T3 (es) | 2011-01-31 | 2016-11-14 | St. Jude Medical, Inc. | Característica de bloqueo antirrotación |
US9717593B2 (en) | 2011-02-01 | 2017-08-01 | St. Jude Medical, Cardiology Division, Inc. | Leaflet suturing to commissure points for prosthetic heart valve |
AU2012212188A1 (en) | 2011-02-02 | 2013-08-29 | St. Jude Medical, Inc. | System and method for loading a collapsile heart valve into a delivery device |
EP2484309B1 (en) | 2011-02-02 | 2019-04-10 | Shlomo Gabbay | Heart valve prosthesis |
CN107334512B (zh) | 2011-02-10 | 2021-04-13 | 可维亚媒体公司 | 用于建立和保持房内压力释放孔的装置 |
US20120209375A1 (en) | 2011-02-11 | 2012-08-16 | Gilbert Madrid | Stability device for use with percutaneous delivery systems |
ES2641902T3 (es) | 2011-02-14 | 2017-11-14 | Sorin Group Italia S.R.L. | Dispositivo de anclaje sin sutura para prótesis valvulares cardiacas |
EP2486894B1 (en) | 2011-02-14 | 2021-06-09 | Sorin Group Italia S.r.l. | Sutureless anchoring device for cardiac valve prostheses |
CN103429193B (zh) | 2011-02-15 | 2015-09-16 | 梅迪瓦尔夫有限公司 | 经皮定位装置 |
WO2012111137A1 (ja) | 2011-02-18 | 2012-08-23 | 株式会社パイオラックスメディカルデバイス | 腹腔-静脈シャント用ステント |
GB2488530A (en) | 2011-02-18 | 2012-09-05 | David J Wheatley | Heart valve |
WO2012161786A1 (en) | 2011-02-25 | 2012-11-29 | University Of Connecticut | Prosthetic heart valve |
US9155619B2 (en) | 2011-02-25 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
PL218575B1 (pl) | 2011-02-28 | 2014-12-31 | Fundacja Rozwoju Kardiochirurgii Im Prof Zbigniewa Religi | Sposób wytwarzania warstw powierzchniowych na implantach medycznych |
US9445898B2 (en) | 2011-03-01 | 2016-09-20 | Medtronic Ventor Technologies Ltd. | Mitral valve repair |
WO2012118508A1 (en) | 2011-03-03 | 2012-09-07 | Empire Technology Development Llc | Temporary perfusion channel percutaneous delivery of balloon-expandable stents |
EP2688516B1 (en) | 2011-03-21 | 2022-08-17 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus |
EP3536282A1 (en) | 2011-03-23 | 2019-09-11 | Daidalos Solutions B.V. | Medical instrument, ring prosthesis, stent and stented valve |
US8900862B2 (en) | 2011-03-23 | 2014-12-02 | The Regents Of The University Of California | Mesh enclosed tissue constructs |
US10016461B2 (en) | 2012-12-03 | 2018-07-10 | The Regents Of The University Of California | Apparatus and process for growing a heart valve in three-dimensions |
US9055937B2 (en) | 2011-04-01 | 2015-06-16 | Edwards Lifesciences Corporation | Apical puncture access and closure system |
US8945212B2 (en) | 2011-04-01 | 2015-02-03 | W. L. Gore & Associates, Inc. | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
US8961599B2 (en) | 2011-04-01 | 2015-02-24 | W. L. Gore & Associates, Inc. | Durable high strength polymer composite suitable for implant and articles produced therefrom |
US11213393B2 (en) | 2011-04-01 | 2022-01-04 | Edwards Lifesciences Corporation | Compressible heart valve annulus sizing templates |
JP6204905B2 (ja) | 2011-04-04 | 2017-09-27 | ザ メディカル リサーチ,インフラストラクチュア,アンド ヘルス サービシーズ ファンド オブ ザ テル アビブ メディカル センター | 心臓弁修復のための装置および方法 |
US20120259405A1 (en) | 2011-04-05 | 2012-10-11 | Boston Scientific Scimed, Inc | Radial Radiopaque Markers |
JP6157007B2 (ja) | 2011-04-20 | 2017-07-05 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・リーランド・スタンフォード・ジュニア・ユニバーシティThe Board Of Trustees Of The Leland Stanford Junior University | 腔内弁作製のためのシステムおよび方法 |
US9381082B2 (en) | 2011-04-22 | 2016-07-05 | Edwards Lifesciences Corporation | Devices, systems and methods for accurate positioning of a prosthetic valve |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
EP2520250B1 (en) | 2011-05-04 | 2014-02-19 | Medtentia International Ltd Oy | Medical device for a cardiac valve implant |
EP2520251A1 (en) | 2011-05-05 | 2012-11-07 | Symetis SA | Method and Apparatus for Compressing Stent-Valves |
EP2522307B1 (en) | 2011-05-08 | 2020-09-30 | ITSO Medical AB | Device for delivery of medical devices to a cardiac valve |
EP2522308B1 (de) | 2011-05-10 | 2015-02-25 | Biotronik AG | Mechanische Transkatheter-Herzklappenprothese |
US9144494B2 (en) | 2011-05-12 | 2015-09-29 | Medtronic, Inc. | Delivery catheter system with micro and macro movement control |
US9486604B2 (en) | 2011-05-12 | 2016-11-08 | Medtronic, Inc. | Packaging and preparation tray for a delivery system |
AU2012256089B2 (en) | 2011-05-13 | 2016-08-04 | Heartware, Inc. | Intravascular blood pump and method of implantation |
JP5925300B2 (ja) | 2011-05-16 | 2016-05-25 | エイチエルティー, インコーポレイテッド | 人工器官のための反転送達デバイスおよび方法 |
EP2709560B1 (en) | 2011-05-17 | 2015-08-05 | Boston Scientific Scimed, Inc. | Annuloplasty ring with piercing wire and segmented wire lumen |
WO2012158189A1 (en) | 2011-05-17 | 2012-11-22 | Boston Scientific Scimed, Inc. | Annuloplasty ring with anchors fixed by curing polymer |
US8945209B2 (en) | 2011-05-20 | 2015-02-03 | Edwards Lifesciences Corporation | Encapsulated heart valve |
ES2841108T3 (es) | 2011-05-26 | 2021-07-07 | On X Life Tech Inc | Manguito de costura de válvula cardíaca |
CA2835862A1 (en) | 2011-05-27 | 2012-12-06 | Cormatrix Cardiovascular, Inc. | Extracellular matrix material valve conduit and methods of making thereof |
US9289282B2 (en) | 2011-05-31 | 2016-03-22 | Edwards Lifesciences Corporation | System and method for treating valve insufficiency or vessel dilatation |
CN103813757A (zh) | 2011-06-01 | 2014-05-21 | 尼奥绰德有限公司 | 心脏瓣膜小叶的微创修复 |
ES2439070T3 (es) | 2011-06-01 | 2014-01-21 | Nvt Ag | Sistema de despliegue de prótesis de válvula cardiaca |
US9402721B2 (en) | 2011-06-01 | 2016-08-02 | Valcare, Inc. | Percutaneous transcatheter repair of heart valves via trans-apical access |
US9101471B2 (en) | 2011-06-13 | 2015-08-11 | Edwards Lifesciences Corporation | Systems and delivery handles for delivering prosthetic heart valves disposed on valve holders |
US20120315260A1 (en) | 2011-06-13 | 2012-12-13 | Svetlana A. Ivanova | Compositions and Methods to Prevent and Treat Biofilms |
JP6257515B2 (ja) | 2011-06-15 | 2018-01-10 | フラクシス インコーポレイテッド | 吻合コネクターおよび送達のためのシステム |
WO2012173995A2 (en) | 2011-06-15 | 2012-12-20 | St. Jude Medical, Inc. | Multi-layer stent |
US8840664B2 (en) | 2011-06-15 | 2014-09-23 | Edwards Lifesciences Corporation | Heart valve prosthesis anchoring device and methods |
US9011523B2 (en) | 2011-06-20 | 2015-04-21 | Jacques Seguin | Prosthetic leaflet assembly for repairing a defective cardiac valve and methods of using the same |
CA2840084C (en) | 2011-06-21 | 2019-11-05 | Foundry Newco Xii, Inc. | Prosthetic heart valve devices and associated systems and methods |
EP3725269A1 (en) | 2011-06-23 | 2020-10-21 | Valtech Cardio, Ltd. | Closure element for use with annuloplasty structure |
EP2723272A4 (en) | 2011-06-24 | 2015-01-28 | Inceptus Medical LLC | SYSTEM FOR PERCUTANEOUS IMPLANTABLE ARTIFICIAL CARDIAC VALVES AND METHODS AND DEVICES THEREOF |
WO2013003228A1 (en) | 2011-06-27 | 2013-01-03 | University Of Maryland, Baltimore | Transapical mitral valve repair device |
US9364326B2 (en) | 2011-06-29 | 2016-06-14 | Mitralix Ltd. | Heart valve repair devices and methods |
US9358107B2 (en) | 2011-06-30 | 2016-06-07 | Edwards Lifesciences Corporation | Systems, dies, and methods for processing pericardial tissue |
US8926588B2 (en) | 2011-07-05 | 2015-01-06 | Medtronic Vascular, Inc. | Steerable delivery catheter |
DE102011106928B4 (de) | 2011-07-08 | 2019-02-07 | Admedes Schuessler Gmbh | Verfahren, Vorrichtung und Verwendung eines Verfahrens zum elektrochemischen Abtragen eines Werkstoffs |
DE102011107551B4 (de) | 2011-07-11 | 2015-05-28 | Universitätsklinikum Schleswig-Holstein | Anuloplastiering |
CA2835893C (en) | 2011-07-12 | 2019-03-19 | Boston Scientific Scimed, Inc. | Coupling system for medical devices |
US8795357B2 (en) | 2011-07-15 | 2014-08-05 | Edwards Lifesciences Corporation | Perivalvular sealing for transcatheter heart valve |
WO2013011502A2 (en) | 2011-07-21 | 2013-01-24 | 4Tech Inc. | Method and apparatus for tricuspid valve repair using tension |
US10010412B2 (en) | 2011-07-27 | 2018-07-03 | Edwards Lifesciences Corporation | Conical crimper |
US9339384B2 (en) | 2011-07-27 | 2016-05-17 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US8893370B2 (en) | 2011-07-28 | 2014-11-25 | St. Jude Medical, Cardiology Division, Inc. | System for loading a collapsible heart valve |
WO2013016519A2 (en) | 2011-07-28 | 2013-01-31 | St. Jude Medical, Cardiology Division, Inc. | System for loading a collapsible heart valve |
GB201113060D0 (en) | 2011-07-29 | 2011-09-14 | Univ Ulster | Tissue scaffold |
WO2013019756A2 (en) | 2011-07-29 | 2013-02-07 | Carnegie Mellon University | Artificial valved conduits for cardiac reconstructive procedures and methods for their production |
US20140324164A1 (en) | 2011-08-05 | 2014-10-30 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US8852272B2 (en) | 2011-08-05 | 2014-10-07 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
CN103857361B (zh) | 2011-08-05 | 2017-03-29 | 加州理工学院 | 经皮的心瓣膜递送系统 |
EP2554139A1 (en) | 2011-08-05 | 2013-02-06 | Centre Hospitalier Universitaire Vaudois | Actuating device for a surgical implant |
EP3417813B1 (en) | 2011-08-05 | 2020-05-13 | Cardiovalve Ltd | Percutaneous mitral valve replacement |
US9872770B2 (en) | 2011-08-11 | 2018-01-23 | St. Jude Medical, Inc. | Apparatus and method for heart valve repair |
AU2012299311B2 (en) | 2011-08-11 | 2016-03-03 | Tendyne Holdings, Inc. | Improvements for prosthetic valves and related inventions |
US9060860B2 (en) | 2011-08-18 | 2015-06-23 | St. Jude Medical, Cardiology Division, Inc. | Devices and methods for transcatheter heart valve delivery |
US11185403B2 (en) | 2011-08-31 | 2021-11-30 | Cook Medical Technologies Llc | Endoluminal prosthesis assembly |
EP2564811B1 (en) | 2011-08-31 | 2021-03-10 | The Cleveland Clinic Foundation | Delivery system for an endoluminal device |
EP2754414A4 (en) | 2011-09-09 | 2015-09-02 | Shinkan Kogyo K K | VALVULE ENDOPROTHESIS, BASIC MATERIAL FOR FORMING VALVULE ENDOPROTHESIS, AND METHOD FOR MANUFACTURING VALVULE ENDOPROTHESIS |
DE102011054176B4 (de) | 2011-09-12 | 2016-02-04 | Highlife Sas | Behandlungs-Katheter-System |
WO2013037805A1 (en) | 2011-09-12 | 2013-03-21 | Highlife Sas | Treatment catheter system |
EP2755602B1 (en) | 2011-09-12 | 2017-08-09 | Highlife SAS | Transcatheter valve prosthesis |
DE102014102725A1 (de) | 2014-02-28 | 2015-09-17 | Highlife Sas | Transkatheter-Klappenprothese |
DE102014102653A1 (de) | 2014-02-28 | 2015-09-03 | Highlife Sas | Transkatheter-Klappenprothese |
US9011468B2 (en) | 2011-09-13 | 2015-04-21 | Abbott Cardiovascular Systems Inc. | Independent gripper |
US8945177B2 (en) | 2011-09-13 | 2015-02-03 | Abbott Cardiovascular Systems Inc. | Gripper pusher mechanism for tissue apposition systems |
US9422615B2 (en) | 2011-09-16 | 2016-08-23 | W. L. Gore & Associates, Inc. | Single step shape memory alloy expansion |
US8870947B2 (en) | 2011-09-16 | 2014-10-28 | W.L. Gore & Associates, Inc. | Medical device fixation anchors |
US8920493B2 (en) | 2011-09-16 | 2014-12-30 | St. Jude Medical, Cardiology Division, Inc. | Systems and methods for holding annuloplasty rings |
WO2013131069A1 (en) | 2012-03-02 | 2013-09-06 | Mehr Medical Llc | Prostheses |
EP2572684B1 (de) | 2011-09-23 | 2016-05-04 | Biotronik AG | Freigabevorrichtung zum Lösen eines medizinischen Implantats von einem Katheter sowie Katheter mit einer Freigabevorrichtung |
US8900295B2 (en) | 2011-09-26 | 2014-12-02 | Edwards Lifesciences Corporation | Prosthetic valve with ventricular tethers |
US9554904B2 (en) | 2011-09-28 | 2017-01-31 | Medtronic CV Luxembourg S.a.r.l. | Distal tip assembly for a heart valve delivery catheter |
EP3689258A1 (en) | 2011-09-30 | 2020-08-05 | Bioventrix, Inc. | Trans-catheter ventricular reconstruction structures, methods, and systems for treatment of confestive heart failure and other conditions |
EP2763708B1 (en) | 2011-10-05 | 2022-01-05 | Boston Scientific Scimed, Inc. | Profile reduction seal for prosthetic heart valve |
FR2980968B1 (fr) | 2011-10-10 | 2013-12-27 | Assist Publ Hopitaux De Paris | Prothese cardiovasculaire en polymere biodegradable comprenant un element tubulaire logeant une valve et procede de fabrication de ladite prothese |
US9655720B2 (en) | 2011-10-13 | 2017-05-23 | The Research Foundation For The State University Of New York | Polymeric heart valve |
CN103889369B (zh) | 2011-10-19 | 2016-09-14 | 托尔福公司 | 用于心脏瓣膜置换术的装置 |
CA2849030C (en) | 2011-10-19 | 2020-10-27 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9827093B2 (en) | 2011-10-21 | 2017-11-28 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US8945146B2 (en) | 2011-10-24 | 2015-02-03 | Medtronic, Inc. | Delivery system assemblies and associated methods for implantable medical devices |
CN102423505B (zh) | 2011-10-27 | 2014-12-10 | 上海微创医疗器械(集团)有限公司 | 膜式渗透汽化式固定人工生物瓣的方法及装置 |
US8986368B2 (en) | 2011-10-31 | 2015-03-24 | Merit Medical Systems, Inc. | Esophageal stent with valve |
WO2013066883A1 (en) | 2011-10-31 | 2013-05-10 | Merit Medical Systems, Inc. | Delivery systems and methods for sheathing and deploying an implantable device |
CN102499993B (zh) | 2011-11-01 | 2014-01-15 | 上海微创医疗器械(集团)有限公司 | 一种边缘刚性化人工生物瓣膜的制备方法 |
EP2591754B1 (en) | 2011-11-10 | 2015-02-25 | Medtentia International Ltd Oy | A device and a method for improving the function of a heart valve |
US9131926B2 (en) | 2011-11-10 | 2015-09-15 | Boston Scientific Scimed, Inc. | Direct connect flush system |
CA3183330A1 (en) | 2011-11-10 | 2013-05-16 | Medtronic, Inc. | System for deploying a device to a distal location across a diseased vessel |
EP2591755A1 (en) | 2011-11-12 | 2013-05-15 | Medtentia International Ltd Oy | Device and method for improving fixation of a medical device |
US8851286B2 (en) | 2011-11-15 | 2014-10-07 | Boston Scientific Scimed Inc. | Dual sterilization containment vessel |
US20130123796A1 (en) | 2011-11-15 | 2013-05-16 | Boston Scientific Scimed, Inc. | Medical device with keyed locking structures |
FR2982763B1 (fr) | 2011-11-17 | 2015-07-17 | Ct Hospitalier Regional Universitaire D Amiens | Implant destine a etre place dans un passage de circulation du sang et dispositif de traitement associe |
US8721587B2 (en) | 2011-11-17 | 2014-05-13 | Medtronic, Inc. | Delivery system assemblies and associated methods for implantable medical devices |
US8951243B2 (en) | 2011-12-03 | 2015-02-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US9480558B2 (en) | 2011-12-05 | 2016-11-01 | Medtronic, Inc. | Transcatheter valve having reduced seam exposure |
EP2787925B1 (en) | 2011-12-06 | 2018-04-18 | Aortic Innovations LLC | Device for endovascular aortic repair |
US9345574B2 (en) | 2011-12-09 | 2016-05-24 | Edwards Lifesciences Corporation | Force-based heart valve sizer |
US9168131B2 (en) | 2011-12-09 | 2015-10-27 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
EP2881083B1 (en) | 2011-12-12 | 2017-03-22 | David Alon | Heart valve repair device |
EP2793969B1 (en) | 2011-12-13 | 2016-09-14 | Boston Scientific Scimed, Inc. | Decalcifying heart valve |
US9078645B2 (en) | 2011-12-19 | 2015-07-14 | Edwards Lifesciences Corporation | Knotless suture anchoring devices and tools for implants |
JP5978312B2 (ja) | 2011-12-20 | 2016-08-24 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 心臓弁を血管内で置換するための装置 |
US9510945B2 (en) | 2011-12-20 | 2016-12-06 | Boston Scientific Scimed Inc. | Medical device handle |
EP2793751B1 (en) | 2011-12-21 | 2019-08-07 | The Trustees of The University of Pennsylvania | Platforms for mitral valve replacement |
US9078747B2 (en) | 2011-12-21 | 2015-07-14 | Edwards Lifesciences Corporation | Anchoring device for replacing or repairing a heart valve |
AU2012268911B2 (en) | 2011-12-22 | 2014-04-24 | Cook Medical Technologies Llc | Endoluminal prosthesis comprising a valve replacement and at least one fenestration |
EP2793743B1 (en) | 2011-12-23 | 2020-11-04 | MyoPowers Medical Technologies France SAS | Medical device comprising an artificial contractile structure |
US9675473B2 (en) | 2011-12-29 | 2017-06-13 | Boston Scientific Scimed, Inc. | Stent with anti-migration features |
ES2523223T3 (es) | 2011-12-29 | 2014-11-24 | Sorin Group Italia S.R.L. | Un kit para la implantación de conductos vasculares protésicos |
EP2609894B1 (en) | 2011-12-31 | 2015-04-01 | Fundacja Rozwoju Kardiochirurgii Im. Prof. Zbigniewa Religi | Heart valve |
US9492265B2 (en) | 2012-01-06 | 2016-11-15 | Emboline, Inc. | Integrated embolic protection devices |
JP6250553B2 (ja) | 2012-01-10 | 2017-12-20 | エドワーズ ライフサイエンシーズ カーディアック エルエルシー | 第2の支柱フィーチャを用いた連接型支持構造 |
FR2985659B1 (fr) | 2012-01-13 | 2015-03-06 | Assist Publ Hopitaux De Paris | Dispositif d'ancrage d'une valve cardiaque prothetique. |
EP2620125B1 (en) | 2012-01-24 | 2017-10-11 | Medtentia International Ltd Oy | An arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve |
CA2986656A1 (en) | 2012-01-25 | 2013-08-01 | Intact Vascular, Inc. | Endoluminal device and method |
WO2013112795A1 (en) | 2012-01-25 | 2013-08-01 | St. Jude Medical, Inc. | Apparatus and method for heart valve repair |
FR2986149B1 (fr) | 2012-01-26 | 2014-12-26 | Ct Hospitalier Universitaire De Clermont Fd | Dispositif de remplacement d'au moins un cordage de la valve mitrale et kit comprenant au moins deux dispositifs |
US9226812B2 (en) | 2012-01-30 | 2016-01-05 | Kawasumi Laboratories, Inc. | Biliary stent |
CN110403735A (zh) | 2012-01-31 | 2019-11-05 | 米特拉尔维尔福科技有限责任公司 | 二尖瓣停放装置、系统和方法 |
CN104540473B (zh) | 2012-02-01 | 2017-06-23 | Hlt 公司 | 可翻转的组织瓣膜和方法 |
WO2013116093A1 (en) | 2012-02-01 | 2013-08-08 | St. Jude Medical, Inc. | Clip delivery system for heart valve repair and method of use |
ES2631652T3 (es) | 2012-02-02 | 2017-09-01 | St. Jude Medical, Cardiology Division, Inc. | Aparato para la reparación de una válvula cardíaca |
EP2811923B1 (en) | 2012-02-07 | 2019-10-16 | Intervene, Inc. | System for endoluminal valve creation |
EP3281608B1 (en) | 2012-02-10 | 2020-09-16 | CVDevices, LLC | Medical product comprising a frame and visceral pleura |
US10420645B2 (en) | 2012-02-15 | 2019-09-24 | Children's Medical Center Corporation | Right ventricular papillary approximation |
US20140100651A1 (en) | 2012-02-21 | 2014-04-10 | California Institute Of Technology | Medical Device Fastener Mechanisms |
CA2865013C (en) | 2012-02-22 | 2020-12-15 | Syntheon Cardiology, Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
CN104334119B (zh) | 2012-02-28 | 2016-10-12 | M阀门技术有限公司 | 单环心脏瓣膜支撑结构 |
EP2819619B1 (en) | 2012-02-29 | 2019-01-16 | ValCare, Inc. | Percutaneous annuloplasty system with anterior-posterior adjustment |
CN104244841B (zh) | 2012-03-06 | 2017-08-29 | 海莱夫简易股份公司 | 具备环绕功能的医疗导管件 |
JP6001280B2 (ja) | 2012-03-09 | 2016-10-05 | 学校法人金沢医科大学 | 心臓矯正ネットの製造方法 |
JP6084775B2 (ja) | 2012-03-09 | 2017-02-22 | 学校法人金沢医科大学 | 心臓矯正ネット |
US10071186B2 (en) | 2012-03-12 | 2018-09-11 | Colorado State University Research Foundation | Glycosaminoglycan and synthetic polymer material for blood-contacting applications |
US10245042B2 (en) | 2012-03-13 | 2019-04-02 | Medtronic Xomed, Inc. | Check valve vented sterilizable powered surgical handpiece |
EP2825107B1 (en) | 2012-03-14 | 2017-07-19 | Université Catholique de Louvain | Device for minimally invasive excision of a heart valve |
GB2500432A (en) | 2012-03-22 | 2013-09-25 | Stephen Brecker | Replacement heart valve with resiliently deformable securing means |
US20130274873A1 (en) | 2012-03-22 | 2013-10-17 | Symetis Sa | Transcatheter Stent-Valves and Methods, Systems and Devices for Addressing Para-Valve Leakage |
EP2886083B1 (en) | 2012-03-23 | 2018-05-16 | Sorin Group Italia S.r.l. | A collapsible valve prosthesis |
US9066800B2 (en) | 2012-03-28 | 2015-06-30 | Medtronic, Inc. | Dual valve prosthesis for transcatheter valve implantation |
US8926694B2 (en) | 2012-03-28 | 2015-01-06 | Medtronic Vascular Galway Limited | Dual valve prosthesis for transcatheter valve implantation |
US9023098B2 (en) | 2012-03-28 | 2015-05-05 | Medtronic, Inc. | Dual valve prosthesis for transcatheter valve implantation |
US9101467B2 (en) | 2012-03-30 | 2015-08-11 | Medtronic CV Luxembourg S.a.r.l. | Valve prosthesis |
ES2552382T3 (es) | 2012-04-04 | 2015-11-27 | Sorin Group Italia S.R.L. | Dispositivo de soporte para prótesis de válvulas cardíacas |
EP2833836B1 (en) | 2012-04-05 | 2018-05-30 | Mvalve Technologies Ltd. | Cardiac valve support structure |
EP2836165B1 (en) | 2012-04-12 | 2015-10-14 | Medivalve Ltd. | Intracorporeal imaging aid (ima) |
WO2013155474A1 (en) | 2012-04-12 | 2013-10-17 | California Institute Of Technology | Percutaneous heart valve delivery systems |
US9999501B2 (en) | 2012-04-18 | 2018-06-19 | Medtronic CV Luxembourg S.a.r.l. | Valve prosthesis |
US9011515B2 (en) | 2012-04-19 | 2015-04-21 | Caisson Interventional, LLC | Heart valve assembly systems and methods |
CN102764169B (zh) | 2012-04-19 | 2015-07-29 | 杭州启明医疗器械有限公司 | 人工心脏瓣膜及其瓣膜支架 |
US9168122B2 (en) | 2012-04-26 | 2015-10-27 | Rex Medical, L.P. | Vascular device and method for valve leaflet apposition |
WO2013163283A2 (en) | 2012-04-27 | 2013-10-31 | Cook Medical Technologies Llc | Anti-aspiration prosthesis |
US9427303B2 (en) | 2012-04-27 | 2016-08-30 | Cook Medical Technologies Llc | Anti-aspiration valve |
US20130289699A1 (en) | 2012-04-30 | 2013-10-31 | St. Jude Medical, Cardiology Division, Inc. | Aortic valve holder with stent protection and/or ability to decrease valve profile |
WO2013169748A1 (en) | 2012-05-09 | 2013-11-14 | Boston Scientific Scimed, Inc. | Reduced profile valve with locking elements |
JP5904429B2 (ja) | 2012-05-15 | 2016-04-13 | バルブ メディカル リミテッド | 折り畳み式経皮弁を組み立てるためのシステムおよび方法 |
CA2872611C (en) | 2012-05-16 | 2020-09-15 | Edwards Lifesciences Corporation | Systems and methods for placing a coapting member between valvular leaflets |
CN104470471B (zh) | 2012-05-16 | 2017-05-31 | 耶拿阀门科技有限责任公司 | 用于引入可扩张的心脏瓣膜假体的导管递送系统和用于治疗心脏瓣膜缺陷的医疗设备 |
WO2016177647A1 (en) | 2015-05-01 | 2016-11-10 | Feops Nv | Method and system for determining a risk of cardiac conduction abnormalities |
CA2871156C (en) | 2012-05-16 | 2020-06-30 | Edwards Lifesciences Corporation | Devices and methods for reducing cardiac valve regurgitation |
AU2013264730B2 (en) | 2012-05-20 | 2018-02-01 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Prosthetic mitral valve |
US9474600B2 (en) | 2012-05-24 | 2016-10-25 | Shanghai Cingular Biotech Corporation | Prosthetic heart valve |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US9642700B2 (en) | 2012-05-31 | 2017-05-09 | St. Jude Medical, Cardiology Division, Inc. | Prosthetic heart valve having a polymeric stent |
US20130325121A1 (en) | 2012-05-31 | 2013-12-05 | Clemson University | Protein based materials, plastic albumin devices and related methods |
DE102012010798A1 (de) | 2012-06-01 | 2013-12-05 | Universität Duisburg-Essen | Implantierbare Vorrichtung zur Verbesserung oder Behebung einer Herzklappeninsuffizienz |
US9301835B2 (en) | 2012-06-04 | 2016-04-05 | Edwards Lifesciences Corporation | Pre-assembled bioprosthetic valve and sealed conduit |
ES2804583T3 (es) | 2012-06-05 | 2021-02-08 | Kardiozis | Endoprótesis y dispositivo de colocación para implantar tal endoprótesis |
FR2991162B1 (fr) | 2012-06-05 | 2015-07-17 | Ass Marie Lannelongue | Endoprothese, notamment vasculaire ou cardiaque, avec elements thrombogenes |
KR102313261B1 (ko) | 2012-06-05 | 2021-10-14 | 메리트 메디컬 시스템즈, 인크. | 식도 스텐트 |
KR102165138B1 (ko) | 2012-06-06 | 2020-10-14 | 로마 비스타 메디컬, 인코포레이티드. | 팽창가능 의료용 디바이스 |
US9597205B2 (en) | 2012-06-06 | 2017-03-21 | Magenta Medical Ltd. | Prosthetic renal valve |
ES2641998T3 (es) | 2012-06-07 | 2017-11-14 | Boston Scientific Scimed, Inc. | Aparato de sustitución de una válvula cardíaca nativa |
US9095428B2 (en) | 2012-06-08 | 2015-08-04 | Cameron International Corporation | Artificial heart system |
US9526610B2 (en) | 2012-06-12 | 2016-12-27 | Medtronic, Inc. | Method and device for percutaneous valve annuloplasty |
US9883941B2 (en) | 2012-06-19 | 2018-02-06 | Boston Scientific Scimed, Inc. | Replacement heart valve |
CA2877230C (en) | 2012-06-22 | 2019-06-25 | Pierre Squara | Heart valve prostheses |
US9289292B2 (en) | 2012-06-28 | 2016-03-22 | St. Jude Medical, Cardiology Division, Inc. | Valve cuff support |
US9918837B2 (en) | 2012-06-29 | 2018-03-20 | St. Jude Medical, Cardiology Division, Inc. | System to assist in the release of a collapsible stent from a delivery device |
US20140005776A1 (en) | 2012-06-29 | 2014-01-02 | St. Jude Medical, Cardiology Division, Inc. | Leaflet attachment for function in various shapes and sizes |
US9241791B2 (en) | 2012-06-29 | 2016-01-26 | St. Jude Medical, Cardiology Division, Inc. | Valve assembly for crimp profile |
US9615920B2 (en) | 2012-06-29 | 2017-04-11 | St. Jude Medical, Cardiology Divisions, Inc. | Commissure attachment feature for prosthetic heart valve |
EP2866847B1 (en) | 2012-07-02 | 2018-08-22 | Boston Scientific Scimed, Inc. | Prosthetic heart valve formation |
US9498202B2 (en) | 2012-07-10 | 2016-11-22 | Edwards Lifesciences Corporation | Suture securement devices |
CN104487026B (zh) | 2012-07-12 | 2016-11-02 | 波士顿科学国际有限公司 | 小外形心脏瓣膜输送系统 |
AU2013292413B2 (en) | 2012-07-20 | 2017-02-02 | Cook Medical Technologies Llc | Implantable medical device having a sleeve |
US9271856B2 (en) | 2012-07-25 | 2016-03-01 | Medtronic Vascular Galway | Delivery catheter with distal moving capsule for transapical prosthetic heart valve delivery |
US9283072B2 (en) | 2012-07-25 | 2016-03-15 | W. L. Gore & Associates, Inc. | Everting transcatheter valve and methods |
US10376360B2 (en) | 2012-07-27 | 2019-08-13 | W. L. Gore & Associates, Inc. | Multi-frame prosthetic valve apparatus and methods |
US9364358B2 (en) | 2012-07-27 | 2016-06-14 | Medinol Ltd. | Catheter with retractable cover and pressurized fluid |
WO2014022124A1 (en) | 2012-07-28 | 2014-02-06 | Tendyne Holdings, Inc. | Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
US9254141B2 (en) | 2012-08-02 | 2016-02-09 | St. Jude Medical, Inc. | Apparatus and method for heart valve repair |
ES2735536T3 (es) | 2012-08-10 | 2019-12-19 | Sorin Group Italia Srl | Una prótesis de válvula y un kit |
US11458007B2 (en) | 2012-08-10 | 2022-10-04 | W. L. Gore & Associates, Inc. | Devices and methods for limiting a depth of penetration for an anchor within an anatomy |
US9468525B2 (en) | 2012-08-13 | 2016-10-18 | Medtronic, Inc. | Heart valve prosthesis |
US10206775B2 (en) | 2012-08-13 | 2019-02-19 | Medtronic, Inc. | Heart valve prosthesis |
US9232995B2 (en) | 2013-01-08 | 2016-01-12 | Medtronic, Inc. | Valve prosthesis and method for delivery |
CN102805676B (zh) | 2012-08-14 | 2015-06-17 | 杭州启明医疗器械有限公司 | 人造瓣膜置换装置的压缩装置 |
DE102012107465A1 (de) | 2012-08-15 | 2014-05-22 | Pfm Medical Ag | Implantierbare Einrichtung zur Verwendung im menschlichen und/oder tierischen Körper zum Ersatz einer Organklappe |
US10022224B2 (en) | 2012-08-17 | 2018-07-17 | On-X Life Technologies, Inc. | Biological chord repair system and methods |
US9649212B2 (en) | 2012-08-30 | 2017-05-16 | Biotronik Ag | Release device for releasing a medical implant from a catheter and catheter comprising a release device |
US9717595B2 (en) | 2012-09-05 | 2017-08-01 | Medtronic Vascular Galway | Trans-aortic delivery system with containment capsule centering device |
DE102012216742A1 (de) | 2012-09-19 | 2014-03-20 | Hans-Hinrich Sievers | Herzklappenprothese |
WO2014044789A1 (en) | 2012-09-21 | 2014-03-27 | Materialise N.V. | Patient-specific intraluminal implants |
US9597436B2 (en) | 2012-09-21 | 2017-03-21 | Osaka University | Advanced heart failure treatment material as myocardial/cardiovascular regeneration device |
CN103655004B (zh) | 2012-09-21 | 2015-11-25 | 上海微创医疗器械(集团)有限公司 | 植入体输送系统 |
US9585748B2 (en) | 2012-09-25 | 2017-03-07 | Edwards Lifesciences Corporation | Methods for replacing a native heart valve and aorta with a prosthetic heart valve and conduit |
CA2885354A1 (en) | 2012-09-29 | 2014-04-03 | Mitralign, Inc. | Plication lock delivery system and method of use thereof |
EP2712633B1 (de) | 2012-10-02 | 2015-04-29 | Biotronik AG | Bioprosthetische Komponenten für ein Implantat, insbesondere teilvernetzte biologische Herzklappen |
WO2014056644A1 (en) | 2012-10-09 | 2014-04-17 | Biotronik Ag | Crimping tool for a prosthetic device and method for crimping a prosthetic device with a crimping tool |
FR2996747B1 (fr) | 2012-10-11 | 2015-02-06 | Cormove | Implant destine a etre insere dans un conduit de circulation du sang |
US9295549B2 (en) | 2012-10-12 | 2016-03-29 | St. Jude Medical, Cardiology Division, Inc. | Valve holder and loading integration |
FR2996748B1 (fr) | 2012-10-12 | 2015-02-06 | Cormove | Dispositif de traitement d'un conduit de circulation du sang |
US9801721B2 (en) | 2012-10-12 | 2017-10-31 | St. Jude Medical, Cardiology Division, Inc. | Sizing device and method of positioning a prosthetic heart valve |
KR102172813B1 (ko) | 2012-10-18 | 2020-11-03 | 로마 비스타 메디컬, 인코포레이티드. | 보강된 팽창가능 의료 장치 |
ES2617182T3 (es) | 2012-10-19 | 2017-06-15 | Boston Scientific Scimed, Inc. | Elemento antitrómbico para dispositivos médicos implantados |
EP2911593B1 (en) | 2012-10-23 | 2020-03-25 | Valtech Cardio, Ltd. | Percutaneous tissue anchor techniques |
EP3517052A1 (en) | 2012-10-23 | 2019-07-31 | Valtech Cardio, Ltd. | Controlled steering functionality for implant-delivery tool |
WO2014066081A1 (en) | 2012-10-24 | 2014-05-01 | Cook Medical Technologies Llc | Anti-reflux prosthesis |
FR2997288B1 (fr) | 2012-10-25 | 2015-01-23 | Cormove | Dispositif de mise en place d'une etancheite autour d'un implant dans un passage de circulation du sang, et necessaire de traitement associe |
US9192751B2 (en) | 2012-10-26 | 2015-11-24 | Medtronic, Inc. | Elastic introducer sheath |
DE102012219752A1 (de) | 2012-10-29 | 2014-04-30 | Aesculap Ag | Stabilisator für Operationen am schlagenden Herzen |
US9636441B2 (en) | 2012-11-05 | 2017-05-02 | Robert Jarvik | Support stent for transvalvular conduit |
US20140128964A1 (en) | 2012-11-08 | 2014-05-08 | Symetis Sa | Stent Seals and Methods for Sealing an Expandable Stent |
US20140135907A1 (en) | 2012-11-09 | 2014-05-15 | Medtronic CV Luxembourg S.a.r.l. | Medical Device Delivery System and Methods of Delivering Medical Devices |
FR2998166B1 (fr) | 2012-11-16 | 2016-02-26 | Engin Oder | Prothese annulaire pour la therapie de la valve mitrale par annulo-plastie |
KR102213051B1 (ko) | 2012-11-20 | 2021-02-08 | 이노브하르트 에세.에레.엘레. | 인공 보철 심장 판막을 이식하기 위해 심방실 내에 가이드 와이어들의 시스템을 전개하는 전개 장치 |
BR112015011672B1 (pt) | 2012-11-20 | 2021-08-31 | Innovheart S.R.L. | Sistema protético para substituição de válvula cardíaca |
EP2922593B1 (en) | 2012-11-21 | 2020-04-08 | Concert Medical, LLC | Preformed guidewire |
US20140142689A1 (en) | 2012-11-21 | 2014-05-22 | Didier De Canniere | Device and method of treating heart valve malfunction |
US9199348B2 (en) | 2012-11-27 | 2015-12-01 | Medtronic, Inc. | Prosthetic valve crimping |
EP2928538B1 (en) | 2012-12-07 | 2018-11-21 | Valcare, Inc. | Devices for percutaneously anchoring annuloplasty rings |
EP2742911A1 (de) | 2012-12-17 | 2014-06-18 | Hans Reiner Figulla | Klappenprothese zum Ersatz einer Atrioventricularklappe |
US9398952B2 (en) | 2012-12-19 | 2016-07-26 | W. L. Gore & Associates, Inc. | Planar zone in prosthetic heart valve leaflet |
US10966820B2 (en) | 2012-12-19 | 2021-04-06 | W. L. Gore & Associates, Inc. | Geometric control of bending character in prosthetic heart valve leaflets |
US10039638B2 (en) | 2012-12-19 | 2018-08-07 | W. L. Gore & Associates, Inc. | Geometric prosthetic heart valves |
US10321986B2 (en) | 2012-12-19 | 2019-06-18 | W. L. Gore & Associates, Inc. | Multi-frame prosthetic heart valve |
US9737398B2 (en) | 2012-12-19 | 2017-08-22 | W. L. Gore & Associates, Inc. | Prosthetic valves, frames and leaflets and methods thereof |
US9101469B2 (en) | 2012-12-19 | 2015-08-11 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with leaflet shelving |
US9144492B2 (en) | 2012-12-19 | 2015-09-29 | W. L. Gore & Associates, Inc. | Truncated leaflet for prosthetic heart valves, preformed valve |
US9968443B2 (en) | 2012-12-19 | 2018-05-15 | W. L. Gore & Associates, Inc. | Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet |
US9008769B2 (en) | 2012-12-21 | 2015-04-14 | Backbeat Medical, Inc. | Methods and systems for lowering blood pressure through reduction of ventricle filling |
CA2933278C (en) | 2013-12-19 | 2023-03-14 | Backbeat Medical, Inc. | Methods and systems for controlling blood pressure by controlling atrial pressure |
US9795479B2 (en) | 2012-12-27 | 2017-10-24 | Venus Medtech (Hangzhou), Inc. | Apparatus and set for folding or unfolding a medical implant comprising a clamping mechanism, implant and method |
WO2014105741A1 (en) | 2012-12-31 | 2014-07-03 | Edwards Lifesciences Corporation | Surgical heart valves adapted for post implant expansion |
EP2752170B1 (en) | 2013-01-08 | 2017-02-22 | Cook Medical Technologies LLC | Multi valve anti-reflux prosthesis |
DE102013200152A1 (de) | 2013-01-08 | 2014-07-10 | AdjuCor GmbH | Herzunterstützungsvorrichtung mit einer selbst-expandierenden Schale |
US9066801B2 (en) | 2013-01-08 | 2015-06-30 | Medtronic, Inc. | Valve prosthesis and method for delivery |
CN105007832B (zh) | 2013-01-09 | 2018-01-23 | 4科技有限公司 | 组织锚状物设备 |
EP2943151B1 (en) | 2013-01-10 | 2017-07-19 | Intervene, Inc. | System for endoluminal valve creation |
US9132007B2 (en) | 2013-01-10 | 2015-09-15 | Medtronic CV Luxembourg S.a.r.l. | Anti-paravalvular leakage components for a transcatheter valve prosthesis |
FR3001121B1 (fr) | 2013-01-18 | 2016-01-15 | Ladjali Mustapha Dr | Pince de traitement d'un tissu corporel et necessaire de traitement associe |
US10130471B2 (en) | 2013-01-25 | 2018-11-20 | Medtentia International Ltd. Oy | Medical system, a device for collecting chordae and/or leaflets and a method therefor |
BR112015017366A8 (pt) | 2013-01-25 | 2019-11-12 | Medtentia Int Ltd Oy | dispositivo médico para facilitar a seleção de um implante de anuloplastia |
CN105101910A (zh) | 2013-01-25 | 2015-11-25 | 梅德坦提亚国际有限公司 | 临时心房支撑装置 |
JP6430404B2 (ja) | 2013-01-25 | 2018-11-28 | メドテンチア インターナショナル エルティーディ オーワイ | 天然の心臓内弁膜の機能代行、および/または、天然の心臓内弁膜の一時的または部分的支援に用いる短期型置換用弁、並びに、この弁の送達方法 |
US10856983B2 (en) | 2013-01-25 | 2020-12-08 | Medtentia International Ltd. Oy | System for cardiac valve repair |
US9308346B2 (en) | 2013-02-01 | 2016-04-12 | Medtronic, Inc. | Devices and methods for crimping and loading a collapsible device into a delivery system |
US9675451B2 (en) | 2013-02-01 | 2017-06-13 | Medtronic CV Luxembourg S.a.r.l. | Anti-paravalvular leakage component for a transcatheter valve prosthesis |
US9439763B2 (en) | 2013-02-04 | 2016-09-13 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
WO2014121280A2 (en) | 2013-02-04 | 2014-08-07 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
EP2953579B1 (en) | 2013-02-06 | 2017-05-31 | Symetis SA | A delivery catheter for a prosthetic valve |
EP2958520B1 (en) | 2013-02-21 | 2018-12-19 | St. Jude Medical, Cardiology Division, Inc. | Transapical delivery system |
EP2769742A1 (en) | 2013-02-22 | 2014-08-27 | Cardiatis S.A. | MRI visible medical device. |
EP2769681B1 (en) | 2013-02-22 | 2019-08-21 | Biotronik AG | Release device for detaching a medical implant from an insertion device and an insertion device comprising a release device |
US9155616B2 (en) | 2013-02-28 | 2015-10-13 | St. Jude Medical, Cardiology Division, Inc. | Prosthetic heart valve with expandable microspheres |
CA2902907C (en) | 2013-02-28 | 2017-07-18 | Mark Wood | Implantable medical devices for reduced tissue inflammation |
JP6205436B2 (ja) | 2013-03-01 | 2017-09-27 | コーマトリックス カーディオバスキュラー, インコーポレイテッドCorMatrix Cardiovascular, Inc. | アンカーで固定される心臓血管弁 |
EP2964152B1 (en) | 2013-03-07 | 2021-04-28 | Medtronic Vascular Galway | Prosthesis for transcatheter valve implantation |
ITPI20130015A1 (it) | 2013-03-07 | 2014-09-08 | S M Scienzia Machinale S R L | Apparecchiatura e metodo per la produzione di un oggetto tridimensionale biocompatibile |
WO2014137805A1 (en) | 2013-03-08 | 2014-09-12 | St. Jude Medical, Cardiology Division, Inc. | Method of preparing a tissue swatch for a bioprosthetic device |
WO2014138599A1 (en) | 2013-03-08 | 2014-09-12 | Carnegie Mellon University | Expandable implantable conduit |
US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
US9119713B2 (en) | 2013-03-11 | 2015-09-01 | St. Jude Medical, Cardiology Division, Inc. | Transcatheter valve replacement |
US9808364B2 (en) | 2013-03-11 | 2017-11-07 | Cook Medical Technologies Llc | Systems and methods for maintaining perfusion of branch vessels |
US9744032B2 (en) | 2013-03-11 | 2017-08-29 | Cook Medical Technologies Llc | Endoluminal prosthesis comprising a valve and an axially extendable segment |
EP2967853B1 (en) | 2013-03-12 | 2019-11-06 | Medtronic Inc. | Heart valve prosthesis |
US8986375B2 (en) | 2013-03-12 | 2015-03-24 | Medtronic, Inc. | Anti-paravalvular leakage component for a transcatheter valve prosthesis |
US9398951B2 (en) | 2013-03-12 | 2016-07-26 | St. Jude Medical, Cardiology Division, Inc. | Self-actuating sealing portions for paravalvular leak protection |
WO2014164832A1 (en) | 2013-03-12 | 2014-10-09 | Edwards Lifesciences Corporation | Rapidly deployable surgical heart valves |
CN105142578B (zh) | 2013-03-12 | 2017-05-24 | 爱德华兹生命科学公司 | 用于确保人工心脏瓣膜安全和快速部署的系统和方法 |
CA2905828C (en) | 2013-03-13 | 2023-03-07 | Jenesis Surgical, Llc | Articulated commissure valve stents and methods |
WO2014163795A1 (en) | 2013-03-13 | 2014-10-09 | W. L. Gore & Associates, Inc. | Durable high strength polymer composites suitable for implant and articles produced therefrom |
US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
EP2967807B1 (en) | 2013-03-14 | 2020-07-22 | Valve Medical Ltd. | Temporary valve |
US20140277427A1 (en) | 2013-03-14 | 2014-09-18 | Cardiaq Valve Technologies, Inc. | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
WO2014160330A1 (en) | 2013-03-14 | 2014-10-02 | Millepede, Llc. | Systems and methods for reshaping a heart valve |
JP2016512077A (ja) | 2013-03-14 | 2016-04-25 | カーディオヴァンテージ・メディカル・インク | 塞栓保護デバイスおよび使用方法 |
EP2777616B1 (en) | 2013-03-14 | 2020-08-19 | Edwards Lifesciences CardiAQ LLC | Prosthesis for atraumatically grasping intralumenal tissue |
US9730791B2 (en) | 2013-03-14 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US9326856B2 (en) | 2013-03-14 | 2016-05-03 | St. Jude Medical, Cardiology Division, Inc. | Cuff configurations for prosthetic heart valve |
US9687346B2 (en) | 2013-03-14 | 2017-06-27 | Edwards Lifesciences Corporation | Multi-stranded heat set annuloplasty rings |
US9907681B2 (en) | 2013-03-14 | 2018-03-06 | 4Tech Inc. | Stent with tether interface |
WO2014145811A1 (en) | 2013-03-15 | 2014-09-18 | Edwards Lifesciences Corporation | Valved aortic conduits |
US9289297B2 (en) | 2013-03-15 | 2016-03-22 | Cardiosolutions, Inc. | Mitral valve spacer and system and method for implanting the same |
US8906086B2 (en) | 2013-03-15 | 2014-12-09 | Cook Medical Technologies Llc | Endovascular stent graft with self-closing perfusion branch |
US20140276979A1 (en) | 2013-03-15 | 2014-09-18 | Lsi Solutions, Inc. | Method and devices for securing bidirectional suture loops using coaxial mechanical fasteners |
EP2967861B1 (en) | 2013-03-15 | 2017-11-29 | Hlt, Inc. | Low-profile prosthetic valve structure |
CN105188609B (zh) | 2013-03-15 | 2017-11-10 | 西美蒂斯股份公司 | 涉及经导管支架‑瓣膜的改进 |
US9232998B2 (en) | 2013-03-15 | 2016-01-12 | Cardiosolutions Inc. | Trans-apical implant systems, implants and methods |
US9232994B2 (en) | 2013-03-15 | 2016-01-12 | Medtronic Vascular Galway Limited | Stented prosthetic heart valve and methods for making |
EP2967700B1 (en) | 2013-03-15 | 2020-11-25 | Valcare, Inc. | Systems for delivery of annuloplasty rings |
CN103190968B (zh) | 2013-03-18 | 2015-06-17 | 杭州启明医疗器械有限公司 | 一种支架以及具有该支架的安装稳固的人造瓣膜置换装置 |
FR2998167B1 (fr) | 2013-03-20 | 2015-01-09 | Marco Vola | Dispositif pour realiser une annuloplastie par voie transapicale de la valve mitrale |
DE102013205519B4 (de) | 2013-03-27 | 2019-05-23 | Fehling Instruments Gmbh & Co. Kg | Spreizer für den Vorhof des Herzens |
US9486306B2 (en) | 2013-04-02 | 2016-11-08 | Tendyne Holdings, Inc. | Inflatable annular sealing device for prosthetic mitral valve |
EP2789312A1 (en) | 2013-04-09 | 2014-10-15 | Epygon Sasu | Expandable stent-valve and method for manufacturing a stent |
FR3004638B1 (fr) | 2013-04-19 | 2015-05-29 | Invalv Lab | Implant, notamment destine a etre place dans une valve auriculo-ventriculaire cardiaque, comportant un systeme d'ecartement des bras proximaux |
RU2661057C2 (ru) | 2013-04-19 | 2018-07-11 | Стрейт Эксесс Текнолоджиз Холдингз (Пти) Лтд | Искусственный клапан сердца |
FR3004917B1 (fr) | 2013-04-25 | 2016-06-10 | Bernard Pain | Appareil de mesure du diametre d'une valve aortique |
JP6557217B2 (ja) | 2013-05-01 | 2019-08-07 | アニュメド, インコーポレイテッド | 個別化された大動脈弁補綴具 |
DE102013208038B4 (de) | 2013-05-02 | 2016-09-08 | Michael Siegenthaler | Katheterbasierendes Herzunterstützungssystem |
US9375311B2 (en) | 2013-05-03 | 2016-06-28 | Medtronic, Inc. | Prosthetic valves and associated appartuses, systems and methods |
KR101429005B1 (ko) | 2013-05-06 | 2014-08-12 | 부산대학교 산학협력단 | 심장판막 고정장치 |
US9937330B2 (en) | 2013-05-07 | 2018-04-10 | Cook Medical Technologies Llc | System, method, and kit for providing the diameter of a balloon during treatment |
CN105377192A (zh) | 2013-05-09 | 2016-03-02 | 米塔埃瑟斯医疗有限公司 | 心脏瓣膜辅助修复体 |
EP2994075B1 (en) | 2013-05-10 | 2021-08-04 | Medtronic, Inc. | System for deploying a device to a distal location across a diseased vessel |
EP2803335B1 (en) | 2013-05-14 | 2017-09-27 | Venus MedTech (HangZhou), Inc. | Apparatus for folding or unfolding a medical implant, and implant |
CN107334563B (zh) | 2013-05-20 | 2019-05-14 | 爱德华兹生命科学公司 | 人工心脏瓣膜递送装置 |
US9713696B2 (en) | 2013-05-21 | 2017-07-25 | V-Wave Ltd. | Apparatus and methods for delivering devices for reducing left atrial pressure |
EP2805695A1 (en) | 2013-05-21 | 2014-11-26 | Medtentia International Ltd Oy | Medical system for annuloplasty |
EP2805678B1 (en) | 2013-05-22 | 2017-05-17 | Medtentia International Ltd Oy | Stitching device |
US20160089235A1 (en) | 2013-05-22 | 2016-03-31 | Valcare, Inc. | Transcatheter prosthetic valve for mitral or tricuspid valve replacement |
EP3003452B1 (en) | 2013-05-24 | 2019-09-11 | Bioventrix, Inc. | Cardiac tissue penetrating devices |
CN104173121B (zh) | 2013-05-27 | 2016-05-25 | 上海微创心通医疗科技有限公司 | 用于输送植入体的电动手柄及输送系统 |
US20140358224A1 (en) | 2013-05-30 | 2014-12-04 | Tendyne Holdlings, Inc. | Six cell inner stent device for prosthetic mitral valves |
FR3006582B1 (fr) | 2013-06-05 | 2015-07-17 | Mustapha Ladjali | Dispositif de traitement d'un tissu corporel et necessaire de traitement associe |
WO2014195786A2 (en) | 2013-06-06 | 2014-12-11 | David Alon | Heart valve repair and replacement |
US9980812B2 (en) | 2013-06-14 | 2018-05-29 | Cardiosolutions, Inc. | Mitral valve spacer and system and method for implanting the same |
CN105451684B (zh) | 2013-06-16 | 2017-04-19 | 皮-卡尔迪亚有限公司 | 经皮栓塞保护套 |
WO2014204840A1 (en) | 2013-06-18 | 2014-12-24 | St. Jude Medical, Cardiology Division, Inc. | Transapical introducer |
DE102013106352A1 (de) | 2013-06-18 | 2014-12-18 | Universität Zu Lübeck | Herzunterstützungssystem sowie Herzunterstützungsverfahren |
FR3006884B1 (fr) | 2013-06-18 | 2016-06-24 | Laboratoires Invalv | Dispositif atraumatique d'introduction d'un element tubulaire creux dans un organe biologique |
US10321991B2 (en) | 2013-06-19 | 2019-06-18 | St. Jude Medical, Cardiology Division, Inc. | Collapsible valve having paravalvular leak protection |
US9320841B2 (en) | 2013-06-21 | 2016-04-26 | Corvivo, Inc. | Ventricular assist device |
CN108814772B (zh) | 2013-06-25 | 2020-09-08 | 坦迪尼控股股份有限公司 | 用于假体心脏瓣膜的血栓管理和结构顺应特征 |
WO2015006575A1 (en) | 2013-07-10 | 2015-01-15 | Medtronic Inc. | Helical coil mitral valve annuloplasty systems and methods |
US9237948B2 (en) | 2013-07-11 | 2016-01-19 | Medtronic, Inc. | Delivery system with projections |
WO2015006739A1 (en) | 2013-07-11 | 2015-01-15 | Edwards Lifesciences Corporation | Knotless suture fastener installation system |
US10524904B2 (en) | 2013-07-11 | 2020-01-07 | Medtronic, Inc. | Valve positioning device |
EP2826443B1 (en) | 2013-07-16 | 2017-06-28 | Venus MedTech (HangZhou), Inc. | Set comprising an apparatus and a medical implant |
US9561103B2 (en) | 2013-07-17 | 2017-02-07 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
CN105517616B (zh) | 2013-07-22 | 2019-04-09 | 梅约医学教育与研究基金会 | 用于使引导导管自对中的装置 |
FR3008885B1 (fr) | 2013-07-26 | 2016-12-30 | Landanger | Dispositif chirurgical notamment pour la pose de prothese de cordage mitrale |
US9724083B2 (en) | 2013-07-26 | 2017-08-08 | Edwards Lifesciences Cardiaq Llc | Systems and methods for sealing openings in an anatomical wall |
EP2832318B1 (en) | 2013-07-31 | 2017-04-05 | Venus MedTech (HangZhou), Inc. | Handle assembly for implant delivery apparatus comprising a force limiter, a displacement limiter and/or a brake frame assembly |
EP2832316B1 (en) | 2013-07-31 | 2017-03-29 | Venus MedTech (HangZhou), Inc. | Handle assembly for implant delivery apparatus comprising a displacement limiter, a force limiter and/or a brake frame assembly |
US10363354B2 (en) | 2013-07-31 | 2019-07-30 | Cvdevices, Llc | Unitary body systems and devices and methods to use the same for retroperfusion |
EP2918246B1 (en) | 2014-03-14 | 2018-08-08 | Venus MedTech (HangZhou), Inc. | Heart valve assembly comprising twofold sealing |
EP2918245B1 (en) | 2014-03-14 | 2017-05-03 | Venus MedTech (HangZhou), Inc. | Heart valve comprising a crown piece interconnected to leaflets, a top cuff and a bottom cuff; and a medical implant |
EP2832317B1 (en) | 2013-07-31 | 2017-02-15 | Venus MedTech (HangZhou), Inc. | Implant delivery device for folding or unfolding a medical implant based on a knot |
EP2832315B1 (en) | 2013-07-31 | 2017-11-22 | Venus MedTech (HangZhou), Inc. | Handle assembly for implant delivery apparatus comprising a brake frame assembly, a force limiter and/or a displacement limiter |
JP6465883B2 (ja) | 2013-08-01 | 2019-02-06 | テンダイン ホールディングス,インコーポレイテッド | 心外膜アンカーデバイス及び方法 |
EP2835112B1 (en) | 2013-08-08 | 2021-01-27 | Sorin Group Italia S.r.l. | Heart valve prosthesis |
CN105451686B (zh) | 2013-08-14 | 2018-03-20 | 索林集团意大利有限责任公司 | 用于腱索置换的装置和方法 |
US20150051696A1 (en) | 2013-08-14 | 2015-02-19 | Boston Scientific Scimed, Inc. | Medical guidewire |
WO2015023862A2 (en) | 2013-08-14 | 2015-02-19 | Mitral Valve Technologies Sa | Replacement heart valve apparatus and methods |
WO2015031124A1 (en) | 2013-08-29 | 2015-03-05 | St. Jude Medical, Cardiology Division, Inc. | Transcatheter valve with lyophilized tissue |
AU2014312033A1 (en) | 2013-08-30 | 2016-03-10 | Bioventrix, Inc. | Heart anchor positioning devices, methods, and systems for treatment of congestive heart failure and other conditions |
DK2842581T3 (en) | 2013-08-30 | 2019-02-18 | Georg August Univ Goettingen Stiftung Oeffentlichen Rechts Univsmedizin | Bag-like structure with paracrine activity and process for its preparation |
JP6563394B2 (ja) | 2013-08-30 | 2019-08-21 | イェーナヴァルヴ テクノロジー インコーポレイテッド | 人工弁のための径方向に折り畳み自在のフレーム及び当該フレームを製造するための方法 |
US10123870B2 (en) | 2013-09-12 | 2018-11-13 | St. Jude Medical, Cardiology Division, Inc. | Alignment of an implantable medical device |
EP3043745B1 (en) | 2013-09-12 | 2020-10-21 | St. Jude Medical, Cardiology Division, Inc. | Stent designs for prosthetic heart valves |
GB201316349D0 (en) | 2013-09-13 | 2013-10-30 | Ucl Business Plc | Vascular implant |
JP6659934B2 (ja) | 2013-09-16 | 2020-03-04 | ボストン サイエンティフィック リミテッド | ステントバルブを圧縮/装填するための方法および装置 |
EP2853237A1 (en) | 2013-09-25 | 2015-04-01 | Universität Zürich | Biological heart valve replacement, particularly for pediatric patients, and manufacturing method |
EP3049025B1 (en) | 2013-09-27 | 2018-01-10 | Universität Zürich | Controlling tissue engineered heart valve geometry by using predefined inserts during culture |
EP3052052B1 (en) | 2013-09-30 | 2018-01-17 | The Cleveland Clinic Foundation | Apparatus for treating a regurgitant heart valve |
WO2015057407A1 (en) | 2013-10-05 | 2015-04-23 | Sino Medical Sciences Technology, Inc. | Device and method for mitral valve regurgitation method |
US10869681B2 (en) | 2013-10-17 | 2020-12-22 | Cedars-Sinai Medical Center | Device to percutaneously treat heart valve embolization |
US9788944B2 (en) | 2013-10-21 | 2017-10-17 | St. Jude Medical, Cardiology Division, Inc. | Transcatheter valve implantation access sheaths |
JP6220969B2 (ja) | 2013-10-22 | 2017-10-25 | コンシーヴァルブ エルエルシー | ステント装着した心臓弁または生体補綴弁の狭窄、閉塞、または石灰化を阻害するための方法 |
US10182910B2 (en) | 2013-10-23 | 2019-01-22 | Biotronik Ag | Method for fitting an implant to a catheter |
US10646333B2 (en) | 2013-10-24 | 2020-05-12 | Medtronic, Inc. | Two-piece valve prosthesis with anchor stent and valve component |
US9662202B2 (en) | 2013-10-24 | 2017-05-30 | Medtronic, Inc. | Heart valve prosthesis |
US9414913B2 (en) | 2013-10-25 | 2016-08-16 | Medtronic, Inc. | Stented prosthetic heart valve |
EP3062745B1 (en) | 2013-10-28 | 2018-06-06 | Symetis SA | Stent-valve, delivery apparatus and method of use |
CN104586542B (zh) | 2013-10-31 | 2017-01-04 | 上海微创心通医疗科技有限公司 | 一种将植入体装载到输送系统中的装置和方法 |
EP2870946B1 (en) | 2013-11-06 | 2018-10-31 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular leak sealing mechanism |
ES2582336T3 (es) | 2013-11-08 | 2016-09-12 | Nvt Ag | Sistema de despliegue para implantes vasculares |
CN106456320B (zh) | 2013-11-11 | 2020-01-21 | 爱德华兹生命科学卡迪尔克有限责任公司 | 用于制造支架框架的系统和方法 |
US9839765B2 (en) | 2013-11-12 | 2017-12-12 | St. Jude Medical, Cardiology Division, Inc. | Transfemoral mitral valve repair delivery device |
WO2015073815A1 (en) | 2013-11-15 | 2015-05-21 | Guy's And St. Thomas' Nhs Foundation Trust | Information markers for heart prostheses and methods of using same |
US9889004B2 (en) | 2013-11-19 | 2018-02-13 | St. Jude Medical, Cardiology Division, Inc. | Sealing structures for paravalvular leak protection |
US9848880B2 (en) | 2013-11-20 | 2017-12-26 | James E. Coleman | Adjustable heart valve implant |
US9603600B2 (en) | 2013-11-20 | 2017-03-28 | James E. Coleman | Actuator for deployable implant |
US9622863B2 (en) | 2013-11-22 | 2017-04-18 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
US10098734B2 (en) | 2013-12-05 | 2018-10-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US9504565B2 (en) | 2013-12-06 | 2016-11-29 | W. L. Gore & Associates, Inc. | Asymmetric opening and closing prosthetic valve leaflet |
US9610162B2 (en) | 2013-12-26 | 2017-04-04 | Valtech Cardio, Ltd. | Implantation of flexible implant |
CN103735337B (zh) | 2013-12-31 | 2016-08-17 | 金仕生物科技(常熟)有限公司 | 人工心脏瓣膜成形环 |
CN103750922B (zh) | 2013-12-31 | 2016-07-13 | 金仕生物科技(常熟)有限公司 | 制备人工心脏瓣膜瓣叶的方法 |
US9943408B2 (en) | 2014-01-08 | 2018-04-17 | St. Jude Medical, Cardiology Division, Inc. | Basket delivery system |
US9539090B2 (en) | 2014-01-16 | 2017-01-10 | Cook Medical Technologies Llc | Transaortic valve access device |
EP2896387A1 (en) | 2014-01-20 | 2015-07-22 | Mitricares | Heart valve anchoring device |
US10327890B2 (en) | 2014-01-22 | 2019-06-25 | Biotronik Ag | Thermochemically treated miniature tubes as semifinished products for vascular stents |
WO2015112839A1 (en) | 2014-01-23 | 2015-07-30 | President And Fellows Of Harvard College | Engineered polymeric valves, tubular structures, and sheets and uses thereof |
US20150209141A1 (en) | 2014-01-24 | 2015-07-30 | St. Jude Medical, Cardiology Division, Inc. | Stationary intra-annular halo designs for paravalvular leak (pvl) reduction-passive channel filling cuff designs |
US9820852B2 (en) | 2014-01-24 | 2017-11-21 | St. Jude Medical, Cardiology Division, Inc. | Stationary intra-annular halo designs for paravalvular leak (PVL) reduction—active channel filling cuff designs |
US9750603B2 (en) | 2014-01-27 | 2017-09-05 | Medtronic Vascular Galway | Stented prosthetic heart valve with variable stiffness and methods of use |
CA2937794A1 (en) | 2014-01-28 | 2015-08-06 | Sanford Health | Pararenal and thoracic arch stent graft and methods for use |
EP3099345B1 (en) | 2014-01-31 | 2018-10-10 | Cedars-Sinai Medical Center | Pigtail for optimal aortic valvular complex imaging and alignment |
KR102432831B1 (ko) | 2014-02-04 | 2022-08-12 | 이노브하르트 에세.에레.엘레. | 심장 판막용 인공 디바이스 |
EP2904989A1 (en) | 2014-02-11 | 2015-08-12 | Kephalios S.A.S. | Adjustable annuloplasty device |
EP3104812B1 (en) | 2014-02-14 | 2020-05-13 | Edwards Lifesciences Corporation | Percutaneous leaflet augmentation |
EP2907479A1 (en) | 2014-02-18 | 2015-08-19 | Medtentia International Ltd Oy | A system and a method for delivery of an annuloplasty implant |
EP3107496B1 (en) | 2014-02-18 | 2018-07-04 | St. Jude Medical, Cardiology Division, Inc. | Bowed runners for paravalvular leak protection |
WO2015126711A1 (en) | 2014-02-18 | 2015-08-27 | St. Jude Medical, Cardiology Division, Inc. | Bowed runners and corresponding valve assemblies for paravalvular leak protection |
PL4062874T3 (pl) | 2014-02-18 | 2024-03-04 | Edwards Lifesciences Corporation | Elastyczna ramka dla spojenia |
EP3782585B1 (en) | 2014-02-21 | 2023-06-28 | Mitral Valve Technologies Sàrl | Prosthetic mitral valve and anchoring device |
EP3107497B1 (en) | 2014-02-21 | 2020-07-22 | Edwards Lifesciences CardiAQ LLC | Delivery device for controlled deployment of a replacement valve |
WO2015130768A2 (en) | 2014-02-25 | 2015-09-03 | KUSHWAHA, Sudhir | Ventricular assist device and method |
WO2015128741A2 (en) | 2014-02-28 | 2015-09-03 | Highlife Sas | Transcatheter valve prosthesis |
EP3110370B1 (en) | 2014-02-28 | 2019-05-22 | Highlife SAS | Transcatheter valve prosthesis |
USD755384S1 (en) | 2014-03-05 | 2016-05-03 | Edwards Lifesciences Cardiaq Llc | Stent |
EP2918248A1 (en) | 2014-03-11 | 2015-09-16 | Epygon Sasu | An expandable stent-valve and a delivery device |
EP2918247A1 (en) | 2014-03-11 | 2015-09-16 | Epygon Sasu | A prosthetic valve and a delivery device |
EP2918249B1 (de) | 2014-03-14 | 2020-04-29 | Venus MedTech (HangZhou), Inc. | Supraclaviculäres kathetersystem für einen transseptalen zugang zum linken vorhof und linken ventrikel |
US9668861B2 (en) | 2014-03-15 | 2017-06-06 | Rex Medical, L.P. | Vascular device for treating venous valve insufficiency |
GB2527075A (en) | 2014-03-17 | 2015-12-16 | Daassist As | Percutaneous system, devices and methods |
US10390943B2 (en) | 2014-03-17 | 2019-08-27 | Evalve, Inc. | Double orifice device for transcatheter mitral valve replacement |
CR20160398A (es) | 2014-03-18 | 2016-11-10 | St Jude Medical Cardiology Div Inc | Fijador/sujetador de celda basculante/ alterna para reemplazo de válvula mitral |
ES2711663T3 (es) | 2014-03-18 | 2019-05-06 | Nvt Ag | Implante de válvula cardiaca |
PL2921135T3 (pl) | 2014-03-18 | 2017-09-29 | Nvt Ag | System manipulacyjny protezy zastawki serca |
JP6411043B2 (ja) | 2014-03-20 | 2018-10-24 | 学校法人東邦大学 | 弁尖形成用テンプレート |
EP2923665B1 (de) | 2014-03-26 | 2018-10-17 | Biotronik AG | Kathetervorrichtung zur minimalinvasiven Implantation eines Gefäßimplantats, insbesondere für die interventionelle, kathetergestützte Aortenklappenimplantation |
US10143551B2 (en) | 2014-03-31 | 2018-12-04 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular sealing via extended cuff mechanisms |
EP3967271A1 (en) | 2014-04-01 | 2022-03-16 | Medtronic CV Luxembourg S.à.r.l. | Anti-paravalvular leakage component for a transcatheter valve prosthesis |
EP2926840B1 (de) | 2014-04-02 | 2018-05-09 | Biotronik AG | Verfahren zur Aufbereitung von biologischem Gewebe zur trockenen Verwendung in einem Implantat |
PL2929860T3 (pl) | 2014-04-07 | 2018-01-31 | Nvt Ag | Urządzenie do wszczepiania w serce ssaka |
US11116496B2 (en) | 2014-04-08 | 2021-09-14 | Lsi Solutions, Inc. | Surgical suturing device for a replacement anatomical structure and methods thereof |
US9987129B2 (en) | 2014-04-16 | 2018-06-05 | Alma Mater Studiorum—Università di Bologna | Heart valve prosthesis with integrated electronic circuit for measuring intravalvular electrical impedance, and system for monitoring functionality of the prosthesis |
CN106170270B (zh) | 2014-04-17 | 2019-09-17 | 美敦力瓦斯科尔勒戈尔韦公司 | 铰接的经导管假体关节心脏瓣膜递送系统 |
US10321987B2 (en) | 2014-04-23 | 2019-06-18 | Medtronic, Inc. | Paravalvular leak resistant prosthetic heart valve system |
FR3020265B1 (fr) | 2014-04-24 | 2019-09-06 | Cormove | Dispositif de mise en place d'une etancheite autour d'un implant dans un passage de circulation du sang, et necessaire de traitement associe |
US10154904B2 (en) | 2014-04-28 | 2018-12-18 | Edwards Lifesciences Corporation | Intravascular introducer devices |
WO2015169866A1 (en) | 2014-05-06 | 2015-11-12 | Dsm Ip Assets B.V. | Prosthetic valve and method of making a prosthetic valve |
CN106572907B (zh) | 2014-05-06 | 2019-07-26 | 帝斯曼知识产权资产管理有限公司 | 制造人工瓣膜的方法和利用所述方法得到的瓣膜 |
EP3139861B1 (en) | 2014-05-06 | 2020-05-27 | DSM IP Assets B.V. | Method of making a prosthetic valve and valve obtained therewith |
US10195025B2 (en) | 2014-05-12 | 2019-02-05 | Edwards Lifesciences Corporation | Prosthetic heart valve |
USRE49792E1 (en) | 2014-05-14 | 2024-01-09 | Corcym S.R.L. | Implant device and implantation kit |
ES2795358T3 (es) | 2014-05-16 | 2020-11-23 | St Jude Medical Cardiology Div Inc | Sellado subanular para protección de fugas paravalvulares |
CN106456328A (zh) | 2014-05-19 | 2017-02-22 | 爱德华兹生命科学卡迪尔克有限责任公司 | 带有环形活瓣的二尖瓣膜替代品 |
EP3145451B1 (en) | 2014-05-21 | 2020-11-11 | Maleti, Oscar | Prosthetic valve for treating diseases causing reflux affecting the lower limbs |
JP6806670B2 (ja) | 2014-05-21 | 2021-01-06 | スウァット メディカル エービー | 改善された塞栓防御デバイスおよび方法 |
WO2015179468A1 (en) | 2014-05-21 | 2015-11-26 | St. Jude Medical, Cardiology Division, Inc. | Self-expanding heart valves for coronary perfusion and sealing |
US9757232B2 (en) | 2014-05-22 | 2017-09-12 | Edwards Lifesciences Corporation | Crimping apparatus for crimping prosthetic valve with protruding anchors |
EP3145450B1 (en) | 2014-05-22 | 2019-07-17 | St. Jude Medical, Cardiology Division, Inc. | Stents with anchoring sections |
FR3021208B1 (fr) | 2014-05-23 | 2021-03-12 | Thomas Modine | Prothese de valve cardiaque mitrale ou tricuspide |
EP3134033B1 (en) | 2014-05-29 | 2018-04-04 | Edwards Lifesciences CardiAQ LLC | Prosthesis and delivery device |
FR3021860A1 (fr) | 2014-06-05 | 2015-12-11 | Bernard Pain | Dispositif transcatheter pour l'ablation de tissus calcifies au niveau des volets d'une valve aortique |
FR3021863A1 (fr) | 2014-06-05 | 2015-12-11 | Bernard Pain | Dispositif d'introduction transcatheter dans la racine aortique au niveau de la jonction sino tubulaire |
US9532870B2 (en) | 2014-06-06 | 2017-01-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US9855140B2 (en) | 2014-06-10 | 2018-01-02 | St. Jude Medical, Cardiology Division, Inc. | Stent cell bridge for cuff attachment |
FR3021862B1 (fr) | 2014-06-10 | 2016-05-20 | Vygon | Kit d'operation pour mise en place de valve aortique |
ES2675559T3 (es) | 2014-06-12 | 2018-07-11 | The Cleveland Clinic Foundation | Dispositivo y sistema para tratar una válvula cardíaca regurgitante |
PL3157467T3 (pl) | 2014-06-17 | 2019-01-31 | Consiglio Nazionale Delle Ricerche | Sposób wytwarzania zastawki serca z materiału polimerowego i zastawka serca uzyskana tym sposobem |
WO2015195823A1 (en) | 2014-06-18 | 2015-12-23 | Middle Peak Medical, Inc. | Mitral valve implants for the treatment of valvular regurgitation |
WO2015193728A2 (en) | 2014-06-19 | 2015-12-23 | 4Tech Inc. | Cardiac tissue cinching |
JP6740140B2 (ja) | 2014-06-24 | 2020-08-12 | ポラレス・メディカル・インコーポレイテッド | インプラントを固定するためのシステムおよび方法 |
US9700412B2 (en) | 2014-06-26 | 2017-07-11 | Mitralix Ltd. | Heart valve repair devices for placement in ventricle and delivery systems for implanting heart valve repair devices |
WO2016001382A2 (en) | 2014-07-02 | 2016-01-07 | Medtentia International Ltd Oy | Clip for a medical implant |
EP3193782B1 (en) | 2014-07-03 | 2022-03-02 | Medtentia International Ltd Oy | An annuloplasty system |
CN104055604B (zh) | 2014-07-07 | 2016-06-01 | 宁波健世生物科技有限公司 | 一种带锚定装置的心脏瓣膜植入器械 |
FR3023704B1 (fr) | 2014-07-15 | 2016-08-26 | Mustapha Ladjali | Dispositif de traitement endovasculaire d'une valve cardiaque en vue d'un remplacement valvulaire percutane |
WO2016008526A1 (de) | 2014-07-16 | 2016-01-21 | Universitätsklinikum Jena | Herzklappenprothese zum perkutanen ersatz einer trikuspidalklappe und system mit einer derartigen herzklappenprothese |
EP3154474B1 (de) | 2014-07-16 | 2021-11-10 | P+F Products + Features GmbH | Herzklappenprothese zum perkutanen ersatz einer trikuspidalklappe, set und system mit einer derartigen herzklappenprothese |
US9180005B1 (en) | 2014-07-17 | 2015-11-10 | Millipede, Inc. | Adjustable endolumenal mitral valve ring |
CN106999174B (zh) | 2014-07-17 | 2019-08-23 | 核心医疗股份公司 | 用于心瓣修复的医疗设备及方法 |
WO2016016899A1 (en) | 2014-07-30 | 2016-02-04 | Mitraltech Ltd. | Articulatable prosthetic valve |
EP2979667B2 (de) | 2014-07-30 | 2020-10-28 | Biotronik AG | Einführvorrichtung für ein medizinisches implantat in einen menschlichen und/oder tierischen körper |
EP2979664B1 (en) | 2014-08-01 | 2019-01-09 | Alvimedica Tibbi Ürünler Sanayi Ve Dis Ticaret A.S | Aortic valve prosthesis, particularly suitable for transcatheter implantation |
US9801719B2 (en) | 2014-08-15 | 2017-10-31 | Edwards Lifesciences Corporation | Annulus rings with suture clips |
EP3182930B1 (en) | 2014-08-18 | 2020-09-23 | St. Jude Medical, Cardiology Division, Inc. | Sensors for prosthetic heart devices |
EP3182932B1 (en) | 2014-08-18 | 2019-05-15 | St. Jude Medical, Cardiology Division, Inc. | Annuloplasty ring with sensor |
JP5738461B1 (ja) | 2014-09-08 | 2015-06-24 | 重之 尾崎 | 弁尖サイザー |
WO2016038017A1 (en) | 2014-09-08 | 2016-03-17 | Medtentia International Ltd Oy | Annuloplasty implant |
EP3193791B1 (en) | 2014-09-09 | 2018-08-22 | Occlutech Holding AG | A flow regulating device in the heart |
US9827094B2 (en) | 2014-09-15 | 2017-11-28 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with retention elements |
GB2536538B (en) | 2014-09-17 | 2018-07-18 | Cardiomech As | Anchor for implantation in body tissue |
EP3000436B1 (de) | 2014-09-24 | 2017-04-05 | Alexander Lauten | System zum Ersatz einer an einer Entzündung oder einer Infektion erkrankten Klappe des Herzens |
CN105705116B (zh) | 2014-09-24 | 2017-09-29 | 索林集团意大利有限责任公司 | 用于心脏瓣膜假体的托架、相应的存储布置、输送仪器和组件 |
ES2676060T3 (es) | 2014-09-26 | 2018-07-16 | Nvt Ag | Dispositivo implantable para el tratamiento de la regurgitación de la válvula mitral |
US10751183B2 (en) | 2014-09-28 | 2020-08-25 | Edwards Lifesciences Corporation | Apparatuses for treating cardiac dysfunction |
US10390950B2 (en) | 2014-10-03 | 2019-08-27 | St. Jude Medical, Cardiology Division, Inc. | Flexible catheters and methods of forming same |
DE102014114762B3 (de) | 2014-10-10 | 2016-03-03 | Asanus Medizintechnik Gmbh | Aortenklappenklemme und Instrumentensatz zur Aortenklappenrekonstruktion |
WO2016059084A2 (en) | 2014-10-13 | 2016-04-21 | Symetis Sa | Catheter delivery system for stent valve |
EP3009104B1 (en) | 2014-10-14 | 2019-11-20 | St. Jude Medical, Cardiology Division, Inc. | Flexible catheter and methods of forming same |
EP4331503A3 (en) | 2014-10-14 | 2024-06-05 | Edwards Lifesciences Innovation (Israel) Ltd. | Leaflet-restraining techniques |
FR3027212A1 (fr) | 2014-10-16 | 2016-04-22 | Seguin Jacques | Implant intervalvulaire pour valve mitrale |
US10105225B2 (en) | 2014-10-22 | 2018-10-23 | Medtronic, Inc. | Devices, systems and methods for tissue approximation, including approximating mitral valve leaflets |
US10456168B2 (en) | 2014-10-30 | 2019-10-29 | Peter Osypka Stiftung | Transmyocardial insertion unit and its use |
US10213307B2 (en) | 2014-11-05 | 2019-02-26 | Medtronic Vascular, Inc. | Transcatheter valve prosthesis having an external skirt for sealing and preventing paravalvular leakage |
CA2967241C (en) | 2014-11-17 | 2023-01-31 | Mitrassist Medical Ltd. | Heart valve prosthesis |
DE102014223522A1 (de) | 2014-11-18 | 2016-05-19 | Hans-Hinrich Sievers | Biologische Herzklappenprothese |
WO2016083351A1 (en) | 2014-11-24 | 2016-06-02 | Biotronik Ag | Method for producing a storable molded body made of bacterial cellulose and a molded body produced according to the method |
US9907547B2 (en) | 2014-12-02 | 2018-03-06 | 4Tech Inc. | Off-center tissue anchors |
CR20170245A (es) | 2014-12-05 | 2017-09-14 | Edwards Lifesciences Corp | Cateter dirigible con cable de tracción |
CR20170313A (es) | 2014-12-18 | 2017-08-29 | Gore & Ass | Válvulas protésicas con valvas mécanicamente acopladas |
EP3037064B1 (en) | 2014-12-23 | 2018-03-14 | Venus MedTech (HangZhou), Inc. | Minimally invasive mitral valve replacement with brim |
CN109893298A (zh) | 2014-12-19 | 2019-06-18 | 国立研究开发法人国立循环器病研究中心 | 人工瓣膜 |
US20170340786A1 (en) | 2014-12-22 | 2017-11-30 | Synergio Ag | An Implantable Hydraulic Displacement Actuator, System, Manufacturing And Methods Thereof |
US10092428B2 (en) | 2014-12-30 | 2018-10-09 | Cook Medical Technologies Llc | Low profile prosthesis delivery device |
WO2016110735A1 (en) | 2015-01-05 | 2016-07-14 | David Alon | Heart ventricle remodeling |
US9579195B2 (en) | 2015-01-13 | 2017-02-28 | Horizon Scientific Corp. | Mitral bileaflet valve |
WO2016118522A1 (en) | 2015-01-21 | 2016-07-28 | Medtronic Inc. | Prosthetic valve sizer and assembly including same |
WO2016124615A2 (en) | 2015-02-02 | 2016-08-11 | Symetis Sa | Stent seals and method of production |
JP6636527B2 (ja) | 2015-02-03 | 2020-01-29 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 心膜組織を処理する方法、装置およびシステム |
CN107896484B (zh) | 2015-02-05 | 2020-09-08 | 坦迪尼控股股份有限公司 | 可膨胀的心外膜垫及其递送装置和方法 |
US10231834B2 (en) | 2015-02-09 | 2019-03-19 | Edwards Lifesciences Corporation | Low profile transseptal catheter and implant system for minimally invasive valve procedure |
US10039637B2 (en) | 2015-02-11 | 2018-08-07 | Edwards Lifesciences Corporation | Heart valve docking devices and implanting methods |
US20160235525A1 (en) | 2015-02-12 | 2016-08-18 | Medtronic, Inc. | Integrated valve assembly and method of delivering and deploying an integrated valve assembly |
CA2973346C (en) | 2015-02-13 | 2021-07-20 | W.L. Gore & Associates, Inc. | Coherent single layer high strength synthetic polymer composites for prosthetic valves |
EP3261583B1 (en) | 2015-02-24 | 2019-02-13 | Rijksuniversiteit Groningen | Mechanical heart valve prosthesis for the right ventricle |
FR3033494B1 (fr) | 2015-03-10 | 2017-03-24 | Carmat | Endoprothese tissulaire et procede pour sa realisation |
US10758349B2 (en) | 2015-03-13 | 2020-09-01 | Medtronic Vascular, Inc. | Delivery device for prosthetic heart valve with capsule adjustment device |
WO2016150806A1 (en) | 2015-03-20 | 2016-09-29 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath |
WO2016154166A1 (en) | 2015-03-24 | 2016-09-29 | St. Jude Medical, Cardiology Division, Inc. | Prosthetic mitral valve |
CN107157622B (zh) | 2015-03-26 | 2019-12-17 | 杭州启明医疗器械股份有限公司 | 使用安全的瓣膜支架以及具有该瓣膜支架的瓣膜置换装置 |
DE102015206097A1 (de) | 2015-04-02 | 2016-10-06 | Hans-Hinrich Sievers | Herzklappenprothese |
DE102015206098B4 (de) | 2015-04-02 | 2018-09-27 | Hans-Hinrich Sievers | Implantationshilfe für eine biologische Herzklappenprothese sowie Herzklappenprothesensystem |
FR3034642B1 (fr) | 2015-04-07 | 2021-01-15 | Benjamin Faurie | Introducteur pour ensemble de remplacement d'une valve cardiaque ou pour ensemble d'angioplastie coronaire |
EP3078350B1 (en) | 2015-04-09 | 2018-01-31 | Frid Mind Technologies | 3d filter for prevention of stroke |
US10792471B2 (en) | 2015-04-10 | 2020-10-06 | Edwards Lifesciences Corporation | Expandable sheath |
US10327896B2 (en) | 2015-04-10 | 2019-06-25 | Edwards Lifesciences Corporation | Expandable sheath with elastomeric cross sectional portions |
US10368986B2 (en) | 2015-04-15 | 2019-08-06 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery system and method |
ES2818128T3 (es) | 2015-04-16 | 2021-04-09 | Tendyne Holdings Inc | Aparato para el suministro y el reposicionamiento de válvulas protésicas transcatéter |
US9931790B2 (en) | 2015-04-16 | 2018-04-03 | Siemens Healthcare Gmbh | Method and system for advanced transcatheter aortic valve implantation planning |
US10064718B2 (en) | 2015-04-16 | 2018-09-04 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10441416B2 (en) | 2015-04-21 | 2019-10-15 | Edwards Lifesciences Corporation | Percutaneous mitral valve replacement device |
KR101588310B1 (ko) | 2015-04-22 | 2016-01-25 | (주)태웅메디칼 | 심낭막을 이용한 인공심장판막 및 그 제조방법 |
US9782256B2 (en) | 2015-04-27 | 2017-10-10 | Venus Medtech (Hangzhou) Inc | Heart valve assembly |
US10232564B2 (en) | 2015-04-29 | 2019-03-19 | Edwards Lifesciences Corporation | Laminated sealing member for prosthetic heart valve |
CN106175985B (zh) | 2015-04-29 | 2018-08-24 | 上海微创心通医疗科技有限公司 | 用于输送植入体的驱动手柄及输送系统 |
EP3087952A1 (en) | 2015-04-29 | 2016-11-02 | Kephalios S.A.S. | An annuloplasty system and a method for monitoring the effectiveness of an annuloplasty treatment |
US10376363B2 (en) | 2015-04-30 | 2019-08-13 | Edwards Lifesciences Cardiaq Llc | Replacement mitral valve, delivery system for replacement mitral valve and methods of use |
WO2016177562A1 (en) | 2015-05-01 | 2016-11-10 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
US9629720B2 (en) | 2015-05-04 | 2017-04-25 | Jacques Seguin | Apparatus and methods for treating cardiac valve regurgitation |
GB2538072B (en) | 2015-05-05 | 2017-11-15 | Strait Access Tech Holdings (Pty) Ltd | A non-occlusive dilation and deployment catheter device |
JP6595210B2 (ja) | 2015-05-08 | 2019-10-23 | 株式会社日本医療機器開発機構 | 大動脈弁再建術トレーニングキット |
DE102015107242B4 (de) | 2015-05-08 | 2022-11-03 | Highlife Sas | System zum Implantieren eines Implantats um eine umfängliche Gewebestruktur in einem Herz und Verfahren zum Anordnen und Vorbringen eines Implantats auf einem Führungsdraht eines solchen Systems |
US10980973B2 (en) | 2015-05-12 | 2021-04-20 | Ancora Heart, Inc. | Device and method for releasing catheters from cardiac structures |
CN110433010A (zh) | 2015-05-14 | 2019-11-12 | 爱德华兹生命科学公司 | 心脏瓣膜密封装置及其递送装置 |
GB2538749B (en) | 2015-05-27 | 2017-08-02 | Univ Dublin City | Inflatable balloon |
WO2016191338A1 (en) | 2015-05-28 | 2016-12-01 | St. Jude Medical, Cardiology Division, Inc. | System for loading a collapsible heart valve having a leaflet restraining member |
CN110755176B (zh) | 2015-05-28 | 2022-07-08 | 4科技有限公司 | 用于在约束状态下在部署工具内递送的装置 |
DK3539509T3 (da) | 2015-06-01 | 2021-10-11 | Edwards Lifesciences Corp | Indretninger til udbedring af hjerteklapper, der er konfigureret til perkutan indgivelse |
CA2987309C (en) | 2015-06-04 | 2024-01-16 | Epygon | Atrio-ventricular valve stent with native leaflet grasping and holding mechanism |
GB2539444A (en) | 2015-06-16 | 2016-12-21 | Ucl Business Plc | Prosthetic heart valve |
US10881508B2 (en) | 2015-06-30 | 2021-01-05 | Robert V. Snyders | Lifetime regenerative heart valve |
US10695170B2 (en) | 2015-07-02 | 2020-06-30 | Edwards Lifesciences Corporation | Hybrid heart valves adapted for post-implant expansion |
US10716671B2 (en) | 2015-07-02 | 2020-07-21 | Boston Scientific Scimed, Inc. | Prosthetic heart valve composed of composite fibers |
WO2017004374A1 (en) | 2015-07-02 | 2017-01-05 | Edwards Lifesciences Corporation | Integrated hybrid heart valves |
CN108348332A (zh) | 2015-07-03 | 2018-07-31 | 赛姆斯股份公司 | 用于人工瓣膜的球囊导管 |
DE102015212699A1 (de) | 2015-07-07 | 2017-01-12 | AdjuCor GmbH | Implantierbare Vorrichtung zur ortsgenauen Zuführung und Applikation von Substanzen in das Perikard oder auf die Herzoberfläche |
WO2017200956A1 (en) | 2016-05-16 | 2017-11-23 | Elixir Medical Corporation | Uncaging stent |
WO2017011199A1 (en) | 2015-07-16 | 2017-01-19 | St. Jude Medical, Cardiology Division, Inc. | Sutureless prosthetic heart valve |
ITUB20152409A1 (it) | 2015-07-22 | 2017-01-22 | Sorin Group Italia Srl | Manicotto valvolare per protesi valvolari e corrispondente dispositivo |
EP3328318B1 (en) | 2015-07-28 | 2019-08-21 | Boston Scientific Scimed, Inc. | Valve delivery system with pinless release mechanism |
EP3334354B1 (en) | 2015-08-11 | 2021-03-03 | Terumo Corporation | System for implant delivery |
US10709553B2 (en) | 2015-08-12 | 2020-07-14 | Boston Scientific Scimed, Inc. | V-Clip post with pivoting |
US10368983B2 (en) | 2015-08-12 | 2019-08-06 | St. Jude Medical, Cardiology Division, Inc. | Collapsible heart valve including stents with tapered struts |
US10925726B2 (en) | 2015-08-12 | 2021-02-23 | Boston Scientific Scimed, Inc. | Everting leaflet delivery system with pivoting |
AU2016308017B2 (en) | 2015-08-14 | 2020-10-29 | Caisson Interventional Llc | Systems and methods for heart valve therapy |
US10179046B2 (en) | 2015-08-14 | 2019-01-15 | Edwards Lifesciences Corporation | Gripping and pushing device for medical instrument |
US9895222B2 (en) | 2015-08-17 | 2018-02-20 | Venus Medtech (Hangzhou) Inc. | Aortic replacement valve |
US11357499B2 (en) | 2015-08-18 | 2022-06-14 | Lsi Solutions, Inc. | Apparatus for mitral valve repair and methods thereof |
US11026788B2 (en) | 2015-08-20 | 2021-06-08 | Edwards Lifesciences Corporation | Loader and retriever for transcatheter heart valve, and methods of crimping transcatheter heart valve |
US10350066B2 (en) | 2015-08-28 | 2019-07-16 | Edwards Lifesciences Cardiaq Llc | Steerable delivery system for replacement mitral valve and methods of use |
JP2018526109A (ja) | 2015-09-03 | 2018-09-13 | セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド | 拡張可能な部分を有するイントロデューサシース |
WO2017040926A1 (en) | 2015-09-04 | 2017-03-09 | The Trustees Of The University Of Pennsylvania | Systems and methods for percutaneous removal of objects from an internal body space |
EP3347182B1 (en) | 2015-09-11 | 2022-07-13 | S.M. Scienzia Machinale S.r.l | Apparatus and method for producing a biocompatible three-dimensional object |
US10195023B2 (en) | 2015-09-15 | 2019-02-05 | Boston Scientific Scimed, Inc. | Prosthetic heart valves including pre-stressed fibers |
US10478288B2 (en) | 2015-09-30 | 2019-11-19 | Clover Life Sciences Inc. | Trileaflet mechanical prosthetic heart valve |
ES2554296B1 (es) | 2015-10-02 | 2017-01-18 | Jose Ignacio ARAMENDI GALLARDO | Anillo subaórtico reabsorbible |
US10195024B2 (en) | 2015-10-07 | 2019-02-05 | Boston Scientific Scimed, Inc. | Porcine small intestine submucosa leaflet material |
US9872765B2 (en) | 2015-10-12 | 2018-01-23 | Venus Medtech (Hangzhou) Inc | Mitral valve assembly |
US10350067B2 (en) | 2015-10-26 | 2019-07-16 | Edwards Lifesciences Corporation | Implant delivery capsule |
JP6873121B2 (ja) | 2015-10-28 | 2021-05-19 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 大動脈弁状態の情報伝達 |
US10266657B2 (en) | 2015-10-29 | 2019-04-23 | Commonwealth Scientific And Industrial Research Organisation | Polyurethane/urea compositions |
US10321996B2 (en) | 2015-11-11 | 2019-06-18 | Edwards Lifesciences Corporation | Prosthetic valve delivery apparatus having clutch mechanism |
EP3377000B1 (en) | 2015-11-17 | 2023-02-01 | Boston Scientific Scimed, Inc. | Implantable device and delivery system for reshaping a heart valve annulus |
DE102015121501A1 (de) | 2015-12-10 | 2017-06-14 | Biotronik Ag | Einführkatheter und Katheteranordnung |
DK3389557T3 (en) | 2015-12-15 | 2022-08-01 | Neovasc Tiara Inc | Transseptalt leveringssystem |
ES2875921T3 (es) | 2015-12-22 | 2021-11-11 | Medira Ag | Dispositivo protésico de mejora de coaptación de válvula mitral |
AU2016380259B2 (en) | 2015-12-28 | 2020-10-22 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
EP3818963A1 (en) | 2015-12-30 | 2021-05-12 | Caisson Interventional, LLC | Systems for heart valve therapy |
US10426619B2 (en) | 2015-12-30 | 2019-10-01 | Avvie Gmbh | Implant and method for improving coaptation of an atrioventricular valve |
CN108697517B (zh) | 2016-01-14 | 2020-12-01 | 凯雅提斯有限公司 | 用于涉及主动脉瓣功能障碍的胸主动脉疾病的可植入假体 |
CN108882978B (zh) | 2016-01-22 | 2020-11-06 | 梅德坦提亚国际有限公司 | 瓣膜成形术植入物 |
US20170209268A1 (en) | 2016-01-27 | 2017-07-27 | Medtronic, Inc. | Systems and methods for repositioning a fully deployed valve assembly |
US10342660B2 (en) | 2016-02-02 | 2019-07-09 | Boston Scientific Inc. | Tensioned sheathing aids |
US10363130B2 (en) | 2016-02-05 | 2019-07-30 | Edwards Lifesciences Corporation | Devices and systems for docking a heart valve |
WO2017137868A1 (en) | 2016-02-08 | 2017-08-17 | Innoventric Ltd. | Treatment of tricuspid insufficiency |
US10376681B2 (en) | 2016-02-29 | 2019-08-13 | Edwards Lifesciences Corporation | Vacuum-based compliance restoration |
DE102016103843A1 (de) | 2016-03-03 | 2017-09-07 | Biotronik Ag | Reduktion von paravalvulärer Leckage durch kontrollierten Thrombusaufbau |
EP3213714A1 (de) | 2016-03-03 | 2017-09-06 | Biotronik AG | Einführkatheter und katheteranordnung |
US10398549B2 (en) | 2016-03-15 | 2019-09-03 | Abbott Cardiovascular Systems Inc. | System and method for transcatheter heart valve platform |
EP3432832A1 (en) | 2016-03-22 | 2019-01-30 | Assistance Publique - Hôpitaux de Paris | Vascular valved prosthesis and manufacturing method |
CN109561960B (zh) | 2016-03-25 | 2021-11-19 | 项目莫里股份有限公司 | 用于导管、连续体操纵器和其它用途的流体致动的护套位移和铰接特性改进的系统、设备以及方法 |
GB2548891B (en) | 2016-03-31 | 2018-07-04 | I Birdi Ltd | A prosthetic device for mitral valve repair |
DE102016106575A1 (de) | 2016-04-11 | 2017-10-12 | Biotronik Ag | Herzklappenprothese |
US10159569B2 (en) | 2016-04-12 | 2018-12-25 | Lars Erickson | Minimally invasive atrio-ventricular valve treatment by chordae adjustment |
US10624743B2 (en) | 2016-04-22 | 2020-04-21 | Edwards Lifesciences Corporation | Beating-heart mitral valve chordae replacement |
US10485658B2 (en) | 2016-04-22 | 2019-11-26 | Backbeat Medical, Inc. | Methods and systems for controlling blood pressure |
US10406011B2 (en) | 2016-04-28 | 2019-09-10 | Medtronic Vascular, Inc. | Implantable medical device delivery system |
US10231829B2 (en) | 2016-05-04 | 2019-03-19 | Boston Scientific Scimed Inc. | Leaflet stitching backer |
US20170325952A1 (en) | 2016-05-13 | 2017-11-16 | Boston Scientific Scimed, Inc. | Implant release system |
US10583005B2 (en) | 2016-05-13 | 2020-03-10 | Boston Scientific Scimed, Inc. | Medical device handle |
EP3454785B1 (en) | 2016-05-13 | 2021-11-17 | St. Jude Medical, Cardiology Division, Inc. | Heart valve with stent having varying cell densities |
US10667907B2 (en) | 2016-05-13 | 2020-06-02 | St. Jude Medical, Cardiology Division, Inc. | Systems and methods for device implantation |
US11116630B2 (en) | 2016-05-16 | 2021-09-14 | Boston Scientific Scimed, Inc. | Sheathing aid |
US10201416B2 (en) | 2016-05-16 | 2019-02-12 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
ES2924882T3 (es) | 2016-05-16 | 2022-10-11 | Valve Medical Ltd | Vaina de válvula temporal inversora |
US10368982B2 (en) | 2016-05-19 | 2019-08-06 | Boston Scientific Scimed, Inc. | Prosthetic valves, valve leaflets and related methods |
EP3791828B1 (en) | 2016-06-02 | 2022-10-26 | Medtronic Vascular Inc. | Transcatheter valve delivery system with septum hole closure tip assembly |
EP3463120B1 (en) | 2016-06-03 | 2022-07-27 | Intervene, Inc. | Devices for manipulating blood vessel walls and associated systems |
DE102016111323A1 (de) | 2016-06-21 | 2017-12-21 | Biotronik Ag | Einführkatheter und Katheteranordnung |
US10639147B2 (en) | 2016-06-24 | 2020-05-05 | Edwards Lifesciences Corporation | System and method for crimping a prosthetic valve |
CN107550524B (zh) | 2016-07-01 | 2020-01-03 | 先健科技(深圳)有限公司 | 输送装置 |
US10736632B2 (en) | 2016-07-06 | 2020-08-11 | Evalve, Inc. | Methods and devices for valve clip excision |
CN109475408A (zh) | 2016-07-06 | 2019-03-15 | 卫理公会医院 | 包含环形心室耦合机制的假体二尖瓣 |
US10973638B2 (en) | 2016-07-07 | 2021-04-13 | Edwards Lifesciences Corporation | Device and method for treating vascular insufficiency |
US10828150B2 (en) | 2016-07-08 | 2020-11-10 | Edwards Lifesciences Corporation | Docking station for heart valve prosthesis |
WO2018011725A1 (en) | 2016-07-12 | 2018-01-18 | Medtronic, Inc. | Prosthetic valve for regulating fluid flow |
GB201612180D0 (en) | 2016-07-13 | 2016-08-24 | Ucl Business Plc | Bioprosthetic heart valve |
US10058426B2 (en) | 2016-07-20 | 2018-08-28 | Abbott Cardiovascular Systems Inc. | System for tricuspid valve repair |
US10478304B2 (en) | 2016-07-20 | 2019-11-19 | Abbott Cardiovascular Systems Inc. | Independent system for tricuspid valve repair |
US10561423B2 (en) | 2016-07-25 | 2020-02-18 | Virender K. Sharma | Cardiac shunt device and delivery system |
CN106175986B (zh) | 2016-07-26 | 2017-12-01 | 复旦大学附属中山医院 | 一种瓣膜夹合器 |
CA3045638A1 (en) | 2016-07-27 | 2018-02-01 | Sainath Intellectual Properties, Llc | Stent with one-way sock valve |
US11096781B2 (en) | 2016-08-01 | 2021-08-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10856975B2 (en) | 2016-08-10 | 2020-12-08 | Cardiovalve Ltd. | Prosthetic valve with concentric frames |
US10383725B2 (en) | 2016-08-11 | 2019-08-20 | 4C Medical Technologies, Inc. | Heart chamber prosthetic valve implant with base, mesh and dome sections with single chamber anchoring for preservation, supplementation and/or replacement of native valve function |
WO2018035378A1 (en) | 2016-08-18 | 2018-02-22 | 4Tech Inc. | Tissue anchors with flexible tips for insertion into the pericardial cavity |
CR20190069A (es) | 2016-08-26 | 2019-05-14 | Edwards Lifesciences Corp | Valvulas y sistemas de acoplamiento de valvulas corazon |
ES2902516T3 (es) | 2016-08-26 | 2022-03-28 | St Jude Medical Cardiology Div Inc | Válvula cardiaca protésica con características de mitigación de fuga paravalvular |
CN109843219B (zh) | 2016-08-26 | 2022-04-05 | 爱德华兹生命科学公司 | 多部分置换心脏瓣膜假体 |
US10751485B2 (en) | 2016-08-29 | 2020-08-25 | Cephea Valve Technologies, Inc. | Methods, systems, and devices for sealing and flushing a delivery system |
US10575946B2 (en) | 2016-09-01 | 2020-03-03 | Medtronic Vascular, Inc. | Heart valve prosthesis and separate support flange for attachment thereto |
US10786356B2 (en) | 2016-09-15 | 2020-09-29 | Cardiac Implants Llc | Multi-channel apparatus for delivering a constricting cord or a ring to a cardiac valve annulus |
US10456249B2 (en) | 2016-09-15 | 2019-10-29 | St. Jude Medical, Cardiology Division, Inc. | Prosthetic heart valve with paravalvular leak mitigation features |
US10052201B2 (en) | 2016-09-21 | 2018-08-21 | Peijia Medical Co., Ltd. | Valved stent for mitral and tricuspid heart valve replacement |
US10874512B2 (en) | 2016-10-05 | 2020-12-29 | Cephea Valve Technologies, Inc. | System and methods for delivering and deploying an artificial heart valve within the mitral annulus |
FR3057154B1 (fr) | 2016-10-07 | 2018-10-19 | Electroducer | Electrode transcutanee pour ensemble de remplacement d'une valve cardiaque ou ensemble d'angioplastie coronaire comprenant un catheter de delivrance ou un introducteur |
JP7073355B2 (ja) | 2016-10-07 | 2022-05-23 | エレクトロデューサー | 心臓弁を置換するためのアセンブリまたは冠動脈形成アセンブリ |
EP3311774B1 (en) | 2016-10-19 | 2022-05-11 | P+F Products + Features Vertriebs GmbH | Self-expandable atrioventricular valve and system of cardiac valves |
CN107374782B (zh) | 2016-10-20 | 2023-04-18 | 上海微创心通医疗科技有限公司 | 植入体输送装置 |
DE202016105963U1 (de) | 2016-10-24 | 2018-01-25 | Nvt Ag | Intraluminale Gefäßprothese zur Implantation in das Herz oder Herzgefäße eines Patienten |
CA3042021A1 (en) | 2016-10-31 | 2018-05-03 | Cardiac Implants Llc | Flexible radio-opaque protrusions for revealing the position of a constricting cord or annulus ring prior to installation onto a cardiac valve annulus |
US10722356B2 (en) | 2016-11-03 | 2020-07-28 | Edwards Lifesciences Corporation | Prosthetic mitral valve holders |
US11376121B2 (en) | 2016-11-04 | 2022-07-05 | Highlife Sas | Transcatheter valve prosthesis |
US9999502B2 (en) | 2016-11-04 | 2018-06-19 | Highlife Sas | Transcather valve prosthesis |
US10653862B2 (en) | 2016-11-07 | 2020-05-19 | Edwards Lifesciences Corporation | Apparatus for the introduction and manipulation of multiple telescoping catheters |
US10363138B2 (en) | 2016-11-09 | 2019-07-30 | Evalve, Inc. | Devices for adjusting the curvature of cardiac valve structures |
US10398553B2 (en) | 2016-11-11 | 2019-09-03 | Evalve, Inc. | Opposing disk device for grasping cardiac valve tissue |
DE102016013480A1 (de) | 2016-11-11 | 2018-05-17 | Peter Osypka Stiftung | Vorrichtung zur Ballondilatation einer verengten Herzklappe |
FR3058631B1 (fr) | 2016-11-14 | 2019-01-25 | Laboratoires Invalv | Implant de traitement d'une valve biologique |
FR3058632B1 (fr) | 2016-11-14 | 2019-01-25 | Laboratoires Invalv | Dispositif de traitement d'une valve biologique avec organe de poussee de la valve |
US20180133006A1 (en) | 2016-11-15 | 2018-05-17 | Medtronic Vascular, Inc. | Stabilization and advancement system for direct aortic transcatheter aortic valve implantation |
US10959841B2 (en) | 2016-11-15 | 2021-03-30 | Hancock Jaffe Laboratories, Inc. | Implantable vein frame |
CN110177594B (zh) | 2016-11-22 | 2022-07-29 | 波士顿科学国际有限公司 | 抗压缩和/或拉伸的医疗装置轴 |
US11013588B2 (en) | 2016-11-23 | 2021-05-25 | St. Jude Medical, Cardiology Division, Inc. | Tissue heart valve (THV) humidor packaging system |
US10548614B2 (en) | 2016-11-29 | 2020-02-04 | Evalve, Inc. | Tricuspid valve repair system |
WO2018102694A1 (en) | 2016-12-01 | 2018-06-07 | Boston Scientific Scimed, Inc. | Heart valve remodeling device |
FR3060292B1 (fr) | 2016-12-15 | 2019-01-25 | Cmi'nov | Dispositif pour realiser ou preparer une annuloplastie mitrale par voie transfemorale |
JP7440263B2 (ja) | 2016-12-16 | 2024-02-28 | エドワーズ ライフサイエンシーズ コーポレイション | 人工弁用のアンカリングデバイスを送達するための展開システム、ツール、および方法 |
CA3047396A1 (en) | 2016-12-20 | 2018-06-28 | Edwards Lifesciences Corporation | Systems and mechanisms for deploying a docking device for a replacement heart valve |
EP3342355B1 (en) | 2016-12-29 | 2020-04-22 | Medtentia International Ltd Oy | Medical securing device for securing an object with a securing member |
US10463517B2 (en) | 2017-01-16 | 2019-11-05 | Cook Medical Technologies Llc | Controlled expansion stent graft delivery system |
US11185406B2 (en) | 2017-01-23 | 2021-11-30 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
WO2018142275A1 (en) | 2017-02-02 | 2018-08-09 | Valfix Medical Ltd. | Percutaneous valve repair and replacement |
US10682229B2 (en) | 2017-02-08 | 2020-06-16 | 4Tech Inc. | Post-implantation tensioning in cardiac implants |
DE102017202159A1 (de) | 2017-02-10 | 2018-08-16 | Tribio Gmbh | Biologische Transkatheterklappe |
US10492779B2 (en) | 2017-02-20 | 2019-12-03 | Edwards Lifesciences Corporation | Suturing devices for heart valve surgery |
EP3372198B1 (en) | 2017-03-06 | 2019-06-19 | AVVie GmbH | Implant for improving coaptation of an atrioventricular valve |
US10631968B2 (en) | 2017-03-06 | 2020-04-28 | Edwards Lifesciences Corporation | Humidity-management packaging systems and methods |
US10772727B2 (en) | 2017-03-09 | 2020-09-15 | Medtronic Vascular, Inc. | Tension management devices for stented prosthesis delivery device |
US10799685B2 (en) | 2017-03-09 | 2020-10-13 | Edwards Lifesciences Corporation | Expandable sheath with longitudinally extending reinforcing members |
FR3063631B1 (fr) | 2017-03-13 | 2019-03-22 | Cmi'nov | Dispositif de reparation des cordages de la valve mitrale d'un cœur par voie transfemorale |
US11219520B2 (en) | 2017-03-14 | 2022-01-11 | Shape Memory Medical, Inc. | Shape memory polymer foams to seal space around valves |
CN113081391A (zh) | 2017-03-22 | 2021-07-09 | 爱德华兹生命科学公司 | 用于将生物假体装置植入和固定到湿组织的系统和方法 |
WO2018178966A1 (en) | 2017-03-27 | 2018-10-04 | Truleaf Medical Ltd. | Docking elements |
CN110650710B (zh) | 2017-04-06 | 2022-04-26 | 哈珀恩医疗有限公司 | 用于二尖瓣修复的远侧锚固件器械和方法 |
US11224511B2 (en) | 2017-04-18 | 2022-01-18 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
EP3558169B1 (en) | 2017-04-18 | 2022-01-19 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
EP3619136B1 (en) | 2017-05-02 | 2021-04-21 | Medtronic Vascular Inc. | Packaging for dry tissue prosthetic heart valve |
US10959846B2 (en) | 2017-05-10 | 2021-03-30 | Edwards Lifesciences Corporation | Mitral valve spacer device |
IT201700052909A1 (it) | 2017-05-16 | 2018-11-16 | Star Tric S R L | Protesi articolata per valvola tricuspide o mitrale e relativo dispositivo di afferraggio |
HRP20231444T1 (hr) | 2017-05-31 | 2024-03-01 | Edwards Lifesciences Corporation | Brtveni element za protetski srčani zalistak |
CN110740693B (zh) | 2017-06-08 | 2020-07-10 | 4科技有限公司 | 具有绳索停止件的组织锚固件 |
EP3417831B2 (en) | 2017-06-19 | 2023-05-24 | HVR Cardio Oy | Delivery device for an annuloplasty implant |
JP7143340B2 (ja) | 2017-06-30 | 2022-09-28 | ギオラ ウェイズ, | 体内空間内での多次元ナビゲーション |
CN114748212A (zh) | 2017-07-06 | 2022-07-15 | 爱德华兹生命科学公司 | 可操纵轨道递送系统 |
EP4085853A1 (en) | 2017-07-31 | 2022-11-09 | Boston Scientific Scimed, Inc. | Introducer system with expandable capabilities |
DE202017104793U1 (de) | 2017-08-09 | 2018-11-14 | Nvt Ag | Ladesystem für Herzklappenprothesen |
US10973628B2 (en) | 2017-08-18 | 2021-04-13 | Edwards Lifesciences Corporation | Pericardial sealing member for prosthetic heart valve |
US10722353B2 (en) | 2017-08-21 | 2020-07-28 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
IL254099B (en) | 2017-08-22 | 2021-02-28 | Geonovation Medical Tech Ltd | Collapsible one-way valve bushing |
JP7312178B2 (ja) | 2017-08-26 | 2023-07-20 | トランスミューラル システムズ エルエルシー | 心臓弁輪形成及びペーシング処置、関連する装置及び方法 |
EP3681439B1 (en) | 2017-09-12 | 2021-07-28 | Boston Scientific Scimed, Inc. | Percutaneous papillary muscle relocation |
US11786375B2 (en) | 2017-09-13 | 2023-10-17 | Mayo Foundation For Medical Education And Research | Methods and devices for securing epicardial devices |
US10856982B2 (en) | 2017-09-19 | 2020-12-08 | St. Jude Medical, Cardiology Division, Inc. | Transapical mitral valve delivery system |
US20190091013A1 (en) | 2017-09-22 | 2019-03-28 | St. Jude Medical, Cardiology Division, Inc. | Prosthetic Heart Valve with Atraumatic Aortic Portion |
WO2019060821A1 (en) | 2017-09-22 | 2019-03-28 | Boston Scientific Scimed, Inc. | DOME STRUCTURE FOR ENHANCED LEFT VENTRICLE FUNCTION |
FR3071716B1 (fr) | 2017-10-04 | 2023-02-24 | Mdb Texinov | Insert textile a finalite medicale et son procede de fabrication |
FR3072013B1 (fr) | 2017-10-09 | 2019-09-27 | Cmi'nov | Dispositif de suture d'une prothese valvulaire cardiaque |
EP3470105B1 (de) | 2017-10-13 | 2020-04-22 | BIOTRONIK SE & Co. KG | Einführelement für eine medizinische einführeinrichtung |
US10426473B2 (en) | 2017-10-19 | 2019-10-01 | Abbott Cardiovascular Systems Inc. | System and method for plicating a heart valve |
US9895226B1 (en) | 2017-10-19 | 2018-02-20 | Mitral Tech Ltd. | Techniques for use with prosthetic valve leaflets |
JP6761120B2 (ja) | 2017-10-19 | 2020-09-23 | シャンハイ ヘーニュー メディカル テクノロジー カンパニー リミティドShanghai Hanyu Medical Technology Co., Ltd | 弁膜留め具 |
EP3697346B1 (en) | 2017-10-20 | 2022-01-19 | Boston Scientific Scimed, Inc. | Heart valve repair implant for treating tricuspid regurgitation |
EP3476366B1 (en) | 2017-10-27 | 2020-12-16 | Medtentia International Ltd Oy | Annuloplasty implant |
US10912664B2 (en) | 2017-11-21 | 2021-02-09 | Cook Medical Technologies, LLC | Stent with induction responsive muscles that facilitate implantation adjustments |
KR102053451B1 (ko) | 2017-11-24 | 2020-01-08 | (주) 타우피엔유메디칼 | 서클라지 심방 제세동장치 |
EP3498223A1 (en) | 2017-12-13 | 2019-06-19 | Epygon | Crimping device for collapsible valves |
CN108065970B (zh) | 2017-12-14 | 2019-06-25 | 谭雄进 | 一种可多次调节的人工腱索固定组件 |
IT201800000671A1 (it) | 2018-01-10 | 2019-07-10 | Matteo Montorfano | Dispositivo di inserimento di un filo di guida in un vaso sanguigno |
HUE058254T2 (hu) | 2018-01-19 | 2022-07-28 | Edwards Lifesciences Corp | Szívbillentyû-protézis borítással |
DE102018102940B4 (de) | 2018-02-09 | 2019-10-31 | Francisco Javier Carrero Gomez | Vorrichtung zur Prüfung der Funktion einer Aortenklappe |
EP3527170B1 (en) | 2018-02-20 | 2020-11-18 | Institut National des Sciences Appliquées de Lyon | Device for assisting a practitioner in adjusting the length of an artificial chordae implanted in an atrio-ventricular heart valve |
FR3079404B1 (fr) | 2018-03-29 | 2020-03-06 | Electroducer | Ensemble de remplacement d’une valve cardiaque avec assistance de stimulation par voie arterielle ou veineuse peripherique |
DK3787561T3 (da) | 2018-04-30 | 2022-05-30 | Edwards Lifesciences Corp | Indretninger til krympning af proteseimplantat |
US11154389B2 (en) | 2018-05-07 | 2021-10-26 | Medtronic Vascular, Inc. | Assemblies and methods of sterilizing a wet stored implant |
US11147673B2 (en) | 2018-05-22 | 2021-10-19 | Boston Scientific Scimed, Inc. | Percutaneous papillary muscle relocation |
US20210307903A1 (en) | 2018-05-23 | 2021-10-07 | Corcym S.R.L. | A device for the in-situ delivery of heart valve prosthesis |
US11504231B2 (en) | 2018-05-23 | 2022-11-22 | Corcym S.R.L. | Cardiac valve prosthesis |
EP3581232B1 (en) | 2018-06-11 | 2021-02-17 | Dentsply IH AB | Urethral stent and bladder control assembly comprising such a urethral stent |
WO2020032925A1 (en) | 2018-08-07 | 2020-02-13 | 4Tech Inc. | Post-implantation tensioning in cardiac implants |
EP3620133A1 (en) | 2018-09-07 | 2020-03-11 | AVVie GmbH | Implant for improving coaptation of an artrioventricular valve |
FR3085835B1 (fr) | 2018-09-13 | 2020-08-28 | Univ Compiegne Tech | Implant pour valve cardiaque |
US11395738B2 (en) | 2018-09-25 | 2022-07-26 | Truleaf Medical Ltd. | Docking elements |
EP3860530B1 (en) | 2018-10-04 | 2022-02-09 | Stryker Corporation | Medical implant delivery system |
WO2020126001A1 (de) | 2018-12-20 | 2020-06-25 | Medizinische Universität Wien | Stentgraft und vorrichtung zum zuführen und setzen eines solchen stentgrafts in die aorta ascendens |
CN111437065A (zh) | 2019-01-17 | 2020-07-24 | TauPNU医疗有限公司 | 位置可调节的三尖瓣返流手术用器械 |
WO2020174590A1 (ja) | 2019-02-26 | 2020-09-03 | 株式会社iCorNet研究所 | 心臓サポートネット及び植込み型除細動器 |
CA3122187C (en) | 2020-03-17 | 2023-09-05 | Cardiovalve Ltd. | Leaflet-grouping system |
EP3915493B1 (en) | 2020-03-30 | 2022-08-10 | Lepu Medical Technology (Beijing) Co., Ltd. | Heart valve clip |
-
2013
- 2013-02-08 US US13/762,671 patent/US9554897B2/en active Active
- 2013-02-13 CN CN201380017320.1A patent/CN104203158B/zh active Active
- 2013-02-13 EP EP13749578.4A patent/EP2814429A4/en active Pending
- 2013-02-13 AU AU2013220881A patent/AU2013220881B2/en active Active
- 2013-02-13 CN CN201610543000.5A patent/CN105997305B/zh active Active
- 2013-02-13 CA CA2864160A patent/CA2864160C/en active Active
- 2013-02-13 WO PCT/CA2013/000129 patent/WO2013120181A1/en active Application Filing
- 2013-02-13 CA CA3066262A patent/CA3066262C/en active Active
- 2013-02-13 JP JP2014555904A patent/JP6209543B2/ja active Active
-
2016
- 2016-12-14 US US15/378,892 patent/US10363133B2/en active Active
-
2017
- 2017-09-11 JP JP2017174120A patent/JP2018008100A/ja not_active Withdrawn
- 2017-10-06 AU AU2017239620A patent/AU2017239620B2/en active Active
-
2019
- 2019-06-12 US US16/439,170 patent/US11497602B2/en active Active
-
2022
- 2022-10-13 US US17/965,469 patent/US20230036649A1/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101484093A (zh) * | 2006-06-01 | 2009-07-15 | 爱德华兹生命科学公司 | 用于改善心瓣膜功能的人工插入物 |
WO2011069048A2 (en) * | 2009-12-04 | 2011-06-09 | Edward Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US20110208297A1 (en) * | 2010-02-24 | 2011-08-25 | Medtronic Ventor Technologies Ltd. | Mitral Prosthesis and Methods for Implantation |
CN103079498A (zh) * | 2010-05-05 | 2013-05-01 | 内奥瓦斯克公司 | 经导管二尖瓣假体 |
CN104302247A (zh) * | 2011-11-23 | 2015-01-21 | 内奥瓦斯克迪亚拉公司 | 依次展开的经导管二尖瓣假体 |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109843219A (zh) * | 2016-08-26 | 2019-06-04 | 爱德华兹生命科学公司 | 多部分置换心脏瓣膜假体 |
CN109843219B (zh) * | 2016-08-26 | 2022-04-05 | 爱德华兹生命科学公司 | 多部分置换心脏瓣膜假体 |
CN109843218A (zh) * | 2016-12-02 | 2019-06-04 | 赛诺医疗科学技术股份有限公司 | 低轮廓心脏瓣膜和输送系统 |
CN110177525A (zh) * | 2017-02-01 | 2019-08-27 | 美敦力瓦斯科尔勒公司 | 包括扭矩锚定机构的心脏瓣膜假体和用于心脏瓣膜假体的递送装置 |
CN110177525B (zh) * | 2017-02-01 | 2022-04-19 | 美敦力瓦斯科尔勒公司 | 包括扭矩锚定机构的心脏瓣膜假体和用于心脏瓣膜假体的递送装置 |
Also Published As
Publication number | Publication date |
---|---|
EP2814429A1 (en) | 2014-12-24 |
JP2015506768A (ja) | 2015-03-05 |
JP2018008100A (ja) | 2018-01-18 |
US11497602B2 (en) | 2022-11-15 |
CN104203158B (zh) | 2016-08-17 |
AU2013220881A1 (en) | 2014-08-28 |
US20190358032A1 (en) | 2019-11-28 |
WO2013120181A1 (en) | 2013-08-22 |
US9554897B2 (en) | 2017-01-31 |
AU2017239620B2 (en) | 2019-02-07 |
CN105997305B (zh) | 2018-11-13 |
JP6209543B2 (ja) | 2017-10-04 |
CA2864160C (en) | 2020-03-10 |
AU2017239620A1 (en) | 2017-10-26 |
US10363133B2 (en) | 2019-07-30 |
AU2013220881B2 (en) | 2017-10-26 |
CA3066262C (en) | 2023-09-12 |
US20170231760A1 (en) | 2017-08-17 |
CA2864160A1 (en) | 2013-08-22 |
CA3066262A1 (en) | 2013-08-22 |
CN104203158A (zh) | 2014-12-10 |
US20140052237A1 (en) | 2014-02-20 |
US20230036649A1 (en) | 2023-02-02 |
EP2814429A4 (en) | 2015-03-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104203158B (zh) | 用于使瓣膜假体与组织相接合的方法和装置 | |
CN104302247B (zh) | 依次展开的经导管二尖瓣假体 | |
US11793640B2 (en) | Sequentially deployed transcatheter mitral valve prosthesis | |
CN104507424B (zh) | 用于向递送系统上装载假体的方法和设备 | |
US20200222180A1 (en) | Prosthetic valve with anti-pivoting mechanism | |
CN104918583A (zh) | 瓣膜假体和递送方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |