CL2017000888A1 - Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas - Google Patents

Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas

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Publication number
CL2017000888A1
CL2017000888A1 CL2017000888A CL2017000888A CL2017000888A1 CL 2017000888 A1 CL2017000888 A1 CL 2017000888A1 CL 2017000888 A CL2017000888 A CL 2017000888A CL 2017000888 A CL2017000888 A CL 2017000888A CL 2017000888 A1 CL2017000888 A1 CL 2017000888A1
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CL
Chile
Prior art keywords
antibody molecules
bind
affecting
disclosed
infectious
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CL2017000888A
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English (en)
Inventor
Dranoff Glenn
Gordon Freeman James
Arlene Sharpe Helen
Gerhard Frey Johann
Hwai Chang Wen
Jennifer Mataraza Marie
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Novartis Ag
Harvard College
Dana Farber Cancer Inst Inc
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Application filed by Novartis Ag, Harvard College, Dana Farber Cancer Inst Inc filed Critical Novartis Ag
Publication of CL2017000888A1 publication Critical patent/CL2017000888A1/es

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70532—B7 molecules, e.g. CD80, CD86

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Abstract

<p>SE DIVULGAN MOLÉCULAS DE ANTICUERPO QUE SE UNEN ESPECÍFICAMENTE A PD-L1. TAMBIÉN SE DIVULGAN TERAPIAS DE COMBINACIÓN QUE COMPRENDEN MOLÉCULAS DE ANTICUERPO ANTI-PD-LI. LAS MOLÉCULAS DE ANTICUERPO ANTI-PD-LI SE PUEDEN USAR PARA TRATAR, PREVENIR Y/O DIAGNOSTICAR AFECCIONES Y TRASTORNOS CANCEROSOS O INFECCIOSOS.</p>
CL2017000888A 2014-10-14 2017-04-11 Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas CL2017000888A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462063852P 2014-10-14 2014-10-14
US201462094847P 2014-12-19 2014-12-19
US201562198545P 2015-07-29 2015-07-29
US201562213076P 2015-09-01 2015-09-01

Publications (1)

Publication Number Publication Date
CL2017000888A1 true CL2017000888A1 (es) 2017-08-18

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ID=54347916

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CL2017000888A CL2017000888A1 (es) 2014-10-14 2017-04-11 Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas

Country Status (26)

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US (3) US9988452B2 (es)
EP (2) EP4245376A3 (es)
JP (3) JP6877339B2 (es)
KR (1) KR102513870B1 (es)
CN (2) CN107001478B (es)
AU (1) AU2015333687B2 (es)
BR (1) BR112017007379A2 (es)
CA (1) CA2964367C (es)
CL (1) CL2017000888A1 (es)
CO (1) CO2017003490A2 (es)
CR (1) CR20170143A (es)
CU (1) CU20170052A7 (es)
EA (1) EA201790834A1 (es)
EC (1) ECSP17029218A (es)
ES (1) ES2952717T3 (es)
GT (1) GT201700081A (es)
IL (1) IL251563B (es)
MA (1) MA40035A (es)
MX (1) MX2017004810A (es)
PE (1) PE20171067A1 (es)
PH (1) PH12017500692A1 (es)
SG (1) SG11201702401RA (es)
TN (1) TN2017000129A1 (es)
TW (1) TWI716362B (es)
UY (1) UY36351A (es)
WO (1) WO2016061142A1 (es)

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