BE889855A - Procede d'analyse immunometrique - Google Patents

Procede d'analyse immunometrique

Info

Publication number
BE889855A
BE889855A BE0/205580A BE205580A BE889855A BE 889855 A BE889855 A BE 889855A BE 0/205580 A BE0/205580 A BE 0/205580A BE 205580 A BE205580 A BE 205580A BE 889855 A BE889855 A BE 889855A
Authority
BE
Belgium
Prior art keywords
assay process
immunometric assay
immunometric
assay
Prior art date
Application number
BE0/205580A
Other languages
English (en)
French (fr)
Inventor
G S David
H E Greene
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22639055&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE889855(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hybritech Inc filed Critical Hybritech Inc
Publication of BE889855A publication Critical patent/BE889855A/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
BE0/205580A 1980-08-04 1981-08-04 Procede d'analyse immunometrique BE889855A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/175,133 US4376110A (en) 1980-08-04 1980-08-04 Immunometric assays using monoclonal antibodies

Publications (1)

Publication Number Publication Date
BE889855A true BE889855A (fr) 1982-02-04

Family

ID=22639055

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/205580A BE889855A (fr) 1980-08-04 1981-08-04 Procede d'analyse immunometrique

Country Status (5)

Country Link
US (1) US4376110A (OSRAM)
JP (2) JPS57118159A (OSRAM)
BE (1) BE889855A (OSRAM)
CA (1) CA1281640C (OSRAM)
IT (1) IT1225944B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474892A (en) * 1983-02-16 1984-10-02 Board Of Trustees Of The Leland Stanford Junior University Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same

Families Citing this family (1556)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677132A (en) * 1971-05-20 1997-10-14 Strahilevitz; Meir Immunological assay reagent package
US6406920B1 (en) 1980-06-20 2002-06-18 Inverness Medical Switzerland Gmbh Processes and apparatus for carrying out specific binding assays
EP0146654A3 (en) * 1980-06-20 1986-08-20 Unilever Plc Processes and apparatus for carrying out specific binding assays
EP0044219A1 (en) * 1980-07-16 1982-01-20 Unilever Plc Methods of immuno analysis using monoclonal antibodies
NL185309C (nl) * 1980-07-28 1990-03-01 Akzo Nv Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4879219A (en) * 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US4514507A (en) * 1980-11-07 1985-04-30 Secher David S Assay for interferon
US4837167A (en) * 1981-01-30 1989-06-06 Centocor, Inc. Immunoassay for multi-determinant antigens using high-affinity
US4680258A (en) * 1981-03-24 1987-07-14 Sloan-Kettering Institute For Cancer Research Process for sex determination in man by use of monoclonal antibodies to the H-Y antigen
JPS585659A (ja) * 1981-06-24 1983-01-13 ハイブリテツク　インコ−ポレ−テツド 単クロ−ン性抗体を使用する免疫学的、抑制試験
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
EP0072902B1 (de) * 1981-08-21 1985-04-24 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Bestimmung von carcinoembryonalem Antigen (CEA) und zur Bestimmung geeignete Antikörperlösung
US4661586A (en) * 1981-11-17 1987-04-28 The Board Of Trustees Of The Leland Stanford Junior University Monoclonal anti-idiotype antibodies
DE3279029D1 (en) * 1981-12-11 1988-10-20 Welsh Nat School Med Luminescent labelling materials and procedures
USRE32011E (en) * 1981-12-14 1985-10-22 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4444878A (en) * 1981-12-21 1984-04-24 Boston Biomedical Research Institute, Inc. Bispecific antibody determinants
ES521370A0 (es) * 1982-04-12 1985-04-16 Hybritech Inc Un procedimiento para obtener un polidoma.
US4483929A (en) * 1982-05-03 1984-11-20 Liposome Technology Incorporated Liposomes with glycolipid-linked antibodies
US4514505A (en) * 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
US4792528A (en) * 1982-05-21 1988-12-20 The Trustees Of Columbia University In The City Of New York Methods for obtaining monoclonal antibodies useful in enhanced sensitivity immunoassays
US4443427A (en) * 1982-06-21 1984-04-17 Sidney Farber Cancer Institute, Inc. Monoclonal antibody
US4623621A (en) * 1982-06-24 1986-11-18 Hoffmann-La Roche Inc. Immunoassay for peptide and protein oligomers
DE3225027A1 (de) * 1982-07-05 1984-01-05 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemisches messverfahren
US4471058A (en) * 1982-07-26 1984-09-11 Board Of Trustees Operating Michigan State University Method for the detection and/or determination of a polyvalent antigen using at least two different monoclonal antibodies
US4879218A (en) * 1982-09-13 1989-11-07 Virginia Tech Intellectual Properties, Inc. Antibody for C.difficile
JPS5954966A (ja) * 1982-09-22 1984-03-29 Mochida Pharmaceut Co Ltd 免疫学的測定試薬
US4596771A (en) * 1982-09-27 1986-06-24 Research Corporation Monoclonal antibodies to vitamin B-6 and immunossay method
US4659678A (en) * 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
US4845027B1 (en) * 1982-10-13 1994-05-10 Biowhittaker Inc Fluorometric assay of allergic reactions
US4844966A (en) * 1982-10-13 1989-07-04 Minnesota Mining And Manufacturing Company Assaying total IgE levels with fluorogenic enzyme labeled antibody
US4539292A (en) * 1982-12-29 1985-09-03 Reid Michael J Immunoassay technique for specific immunoglobulin E
WO1984002983A1 (en) * 1983-01-21 1984-08-02 Frederick James Primus Specific cea-family antigens, antibodies specific thereto and their methods of use
US4818709A (en) * 1983-01-21 1989-04-04 Primus Frederick J CEA-family antigens, Anti-CEA antibodies and CEA immunoassay
US4525452A (en) * 1983-01-24 1985-06-25 Btc Diagnostics Limited Partnership Enzyme immunoassay with step of immersing sample in deionized water
US4994373A (en) 1983-01-27 1991-02-19 Enzo Biochem, Inc. Method and structures employing chemically-labelled polynucleotide probes
US4849337A (en) * 1983-01-31 1989-07-18 Minnesota Mining And Manufacturing Company Assaying allergen specific IgE levels with fluorogenic enzyme labeled antibody
US4558006A (en) * 1983-02-04 1985-12-10 Kirin-Amgen, Inc. A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin
US5106760A (en) * 1983-02-04 1992-04-21 Kirin-Amgen ATCC HB8209, its monoclonal antibody to erythropoietin and assay using same
FR2541304A1 (fr) * 1983-02-21 1984-08-24 Centre Nat Rech Scient Anticorps monoclonaux anti-legionella, procede d'obtention et application au diagnostic de pneumonies
US5084379A (en) * 1983-04-29 1992-01-28 Biowhittaker, Inc. Fluorometric assay of chymopapain hypersensitivity and reagents therefor
US4851356A (en) * 1983-05-06 1989-07-25 The Trustees Of Columbia University In The City Of New York Immunoassay for human chorionic gonadotropin
JPS60501271A (ja) * 1983-05-06 1985-08-08 ザ・トラステイ−ズ・オブ・コロンビア・ユニヴア−シテイ・イン・ザ・シテイ・オブ・ニユ−・ヨ−ク ヒト絨毛性ゴナドトロピンのイムノアツセイ
US4642284A (en) * 1983-06-13 1987-02-10 Scripps Clinic And Research Foundation Method and system for detection of complement pathway activation
GB8317124D0 (en) * 1983-06-23 1983-07-27 Ekins R P Free ligand assay
USRE34405E (en) * 1983-08-01 1993-10-12 Abbott Laboratories Determination of analytes in particle-containing medium
AU576499B2 (en) * 1983-08-18 1988-09-01 Quidel Suppressive factor of allergy
US4828981A (en) * 1983-08-24 1989-05-09 Synbiotics Corporation Immunoassays for determining Dirofilaria immitis infection using antiidiotype monoclonal antibody reagents
JPS6060557A (ja) * 1983-09-13 1985-04-08 Eisai Co Ltd Ｐｉｖｋａ−２の測定方法および試薬
JPS6080768A (ja) * 1983-10-12 1985-05-08 Eisai Co Ltd 塩基性胎児蛋白の測定方法および試薬
US4595661A (en) * 1983-11-18 1986-06-17 Beckman Instruments, Inc. Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect
US6846654B1 (en) 1983-11-29 2005-01-25 Igen International, Inc. Catalytic antibodies as chemical sensors
US6057121A (en) * 1983-11-29 2000-05-02 Igen International, Inc. Method of catalyzing stereochemical reactions
US5229272A (en) * 1989-04-25 1993-07-20 Igen, Inc. Catalytic antibody components
US4839275A (en) * 1983-12-01 1989-06-13 The Jewish Hospital Circulating antigens of dirofilaria immitis, monoclonal antibodies specific therefor and methods of preparing such antibodies and detecting such antigens
US4683196A (en) * 1983-12-12 1987-07-28 Meru, Inc. Method and materials for the identification of lipopolysaccharide producing microorganisms
EP0168422A1 (en) * 1983-12-12 1986-01-22 Meru, Inc. Method and materials for the identification of lipopolysaccharide producing microorganisms
US4610960A (en) * 1983-12-21 1986-09-09 Wisconsin Alumni Research Foundation Monoclonal antibody to thrombospondin and method for assaying for and isolating thrombospondin
US4666865A (en) * 1984-01-13 1987-05-19 Centocor, Inc. Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies
US4757001A (en) * 1984-02-16 1988-07-12 Fujirebio Kabushiki Kaisha Method of measuring biological ligand by utilizing amylase
GB8404368D0 (en) * 1984-02-20 1984-03-28 Cogent Ltd Monoclonal antibodies to human cytomegalovirus
US4865997A (en) * 1984-02-23 1989-09-12 Becton Dickinson And Company Assay for ligands by separating bound and free tracer from sample
US4690890A (en) * 1984-04-04 1987-09-01 Cetus Corporation Process for simultaneously detecting multiple antigens using dual sandwich immunometric assay
US4780401A (en) * 1984-04-09 1988-10-25 Ciba-Geigy Corporation Novel monoclonal antibodies to human renin and hybridoma cells, processes for their preparation and their applications
GR850899B (OSRAM) * 1984-04-12 1985-11-25 Gen Hospital Corp
US5011771A (en) * 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
CA1260372A (en) * 1984-04-27 1989-09-26 Elazar Rabbani Hybridization method for the detection of genetic materials
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
ZA853756B (en) * 1984-06-01 1986-01-29 Miles Lab Nucleic acid hybridization assay employing immobilized rna probes
US4731326A (en) * 1984-06-04 1988-03-15 Ortho Diagnostic Systems Inc. Disease diagnosis by detection of shed normal tissue antigens
US4636478A (en) * 1984-07-16 1987-01-13 Becton, Dickinson And Company Monoclonal antibodies recognizing L-thyroxine
AU4637185A (en) * 1984-08-01 1986-02-25 Advanced Biotechnology Associates Inc. A salmonella specific analysis reagent
US4707438A (en) * 1984-08-22 1987-11-17 Tel Aviv University Immunoassay for breast cancer employing monoclonal antibodies
BR8506892A (pt) * 1984-08-28 1986-12-09 Hybritech Inc Artigo para ensaios diagnosticos
US4745075A (en) * 1984-09-06 1988-05-17 Burroughs Wellcome Co. Diagnostic test methods
JPS63501096A (ja) * 1984-10-29 1988-04-21 エクス　インコ−ポレ−テツド 小型分子の免疫測定法
DE3587835T2 (de) * 1984-10-31 1994-10-20 Alcon Lab Inc Sandwich-immunotestverfahren für antigene bei ophthalmischen störungen.
US4713347A (en) * 1985-01-14 1987-12-15 Sensor Diagnostics, Inc. Measurement of ligand/anti-ligand interactions using bulk conductance
JPH0672893B2 (ja) * 1985-08-16 1994-09-14 富士薬品工業株式会社 ヒト血中のヒトプロリルヒドロキシラーゼの放射性免疫学的測定法による定量法
DE3508384A1 (de) * 1985-03-08 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Hemmung humaner speichel- und pankreasamylase durch monoklonale antikoerper
DE3509958A1 (de) * 1985-03-20 1986-09-25 Bayer Ag, 5090 Leverkusen Monoklonale antikoerper gegen atriale, natriuretische peptide vom menschen
US4722889A (en) * 1985-04-02 1988-02-02 Leeco Diagnostics, Inc. Immunoassays using multiple monoclonal antibodies and scavenger antibodies
US4707443A (en) * 1985-04-19 1987-11-17 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Soluble interleukin-2 receptor as a disease indicator and a method of assaying the same
US4935339A (en) * 1985-05-07 1990-06-19 Nichols Institute Diagnostics Delayed solid phase immunologic assay
US4737456A (en) * 1985-05-09 1988-04-12 Syntex (U.S.A.) Inc. Reducing interference in ligand-receptor binding assays
US5273882A (en) * 1985-06-13 1993-12-28 Amgen Method and kit for performing nucleic acid hybridization assays
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
US5112738A (en) * 1985-07-03 1992-05-12 Miles Inc. Histamine derivatives, immunogen conjugates and antibodies raised thereto
US4910133A (en) * 1985-08-29 1990-03-20 Ube Industries, Limited Diagnostic test drug comprising monoclonal antibody to human copper.zinc-superoxide dismutase and diagnostic test method using the same
US5063151A (en) * 1985-09-20 1991-11-05 Biometallics, Inc. Immunoassay method and kit
US5595908A (en) * 1985-09-26 1997-01-21 University Of Southern Mississipi Piezoelectric device for detection of polynucleotide hybridization
US4933275A (en) * 1985-10-24 1990-06-12 The General Hospital Corporation Method for the detection of a polypeptide subunit in the presence of a quaternary protein containing the subunit
US6265176B1 (en) 1985-10-29 2001-07-24 Cordis Corporation Dot immunoassay on plastic sheets
US4770993A (en) * 1985-10-31 1988-09-13 Beatrice Companies, Inc. Hybridoma tumor cell lines and their monoclonal antibodies to thaumatin
US5501949A (en) * 1985-12-10 1996-03-26 Murex Diagnostics Corporation Particle bound binding component immunoassay
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
US4810639A (en) * 1985-12-20 1989-03-07 E. I. Du Pont De Nemours And Company Immunoassay for CK-MB using bound and soluble antibodies
US4772551A (en) * 1985-12-26 1988-09-20 Neogen Corporation Method and test kit for detecting a trichothecene using novel monoclonal antibodies
US5175113A (en) * 1986-01-16 1992-12-29 Novo Nordisk A/S Modified β2 -microglobulin
US4741999A (en) * 1986-02-26 1988-05-03 The Research Foundation Of State University Of New York Monoclonal antibodies useful in the identification of microorganisms causing periodontal disease
JPS62231168A (ja) 1986-03-21 1987-10-09 ハイブリテツク・インコ−ポレイテツド アナライト−レセプタ−分析用内部標準を設けるための改良法
WO1987006004A1 (en) * 1986-03-26 1987-10-08 Murex Corporation Device and method for determining microbial resistance to antimicrobic agents
US5292636A (en) * 1986-03-31 1994-03-08 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using soluble T cell surface molecules
US5006459A (en) * 1986-03-31 1991-04-09 T Cell Sciences, Inc. Therapeutic and diagnostic methods using soluble T cell surface molecules
US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
US6881536B1 (en) * 1986-04-30 2005-04-19 Bioveris Corporation Particle based electrochemiluminescent assays
US4963355A (en) * 1986-06-23 1990-10-16 Igen, Inc. Production of antibody catalysts
US5120504A (en) * 1986-07-14 1992-06-09 Hybritech Incorporated Apparatus for immunoassays with vent chennels in the container side wall
ATE120233T1 (de) * 1986-08-06 1995-04-15 Scripps Clinic Res Monoklonale antikörper, b-spezifisch für apolipoprotein, die von zwei hybridomen erzeugt werden.
US4935343A (en) * 1986-08-08 1990-06-19 Syntex (U.S.A.) Inc. Monoclonal antibodies for interleukin-1β
US5316914A (en) * 1986-09-04 1994-05-31 Fuji Yakuhin Kogyo Kabushiki Kaisha Method for determining human collagen peptides by way of enzyme immunoassay
JP2617299B2 (ja) * 1986-09-17 1997-06-04 ダイナボット 株式会社 エラスターゼ１の免疫学的測定方法
US20010023075A1 (en) * 1992-04-03 2001-09-20 Siu-Yin Wong A immunodiagnositc device having a dessicant incorporated therein
US5763262A (en) * 1986-09-18 1998-06-09 Quidel Corporation Immunodiagnostic device
US4828986A (en) * 1986-09-29 1989-05-09 Scripps Clinic And Research Foundation Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample
US4804626A (en) * 1986-10-22 1989-02-14 The General Hospital Corporation Immunometric assay for the detection of human chorionic gonadotropin
US4911909A (en) * 1987-01-02 1990-03-27 E. I. Du Pont De Nemours And Company Method of controlling hypertension using monoclonal antibodies to angiotensin-II
US4940659A (en) * 1987-02-20 1990-07-10 Monoclonetics International, Inc. Screening extra-cellular body fluids for superoxide dismutase (SOD-1) for determining fetal trisomy 21 down syndrome
US5789235A (en) * 1987-03-23 1998-08-04 Tackett; Scott E. Modifying cell metabolism via extra-cellular nucleases
DE3714147A1 (de) * 1987-04-28 1988-11-17 Boehringer Mannheim Gmbh Immunchemisches verfahren und reagenz zur bestimmung eines polyvalenten antigens in einer fluessigen probe
US4788138A (en) * 1987-04-30 1988-11-29 Beckman Instruments, Inc. Method to achieve a linear standard curve in a sandwich immunoassay
US5474899A (en) * 1987-05-13 1995-12-12 Cistron Biotechnology, Inc. Selective immunoassay for IL-1 β
US5149626A (en) * 1987-05-14 1992-09-22 Mclean Hospital Corporation Multiple antigen immunoassay
FR2615622B1 (fr) * 1987-05-19 1994-05-06 Ire Medgenix Sa Dosage plasmatique de monokines
US5009998A (en) * 1987-06-26 1991-04-23 E. I. Du Pont De Nemours And Company Method for performing heterogeneous immunoassay
US4971904A (en) * 1987-06-26 1990-11-20 E. I. Du Pont De Nemours And Company Heterogeneous immunoassay
US5179000A (en) * 1987-07-24 1993-01-12 Nippon Kayaku Kabushiki Kaisha Method for assaying basic fetoprotein in urine and assay kit therefor
US5447837A (en) * 1987-08-05 1995-09-05 Calypte, Inc. Multi-immunoassay diagnostic system for antigens or antibodies or both
AU2425788A (en) * 1987-09-02 1989-03-31 Neville R. Kallenbach Production of immunoproximity catalysts
US6461825B1 (en) * 1987-09-30 2002-10-08 Sanofi (Societe Anonyme) Immunometric assay kit and method applicable to whole cells
US4859612A (en) * 1987-10-07 1989-08-22 Hygeia Sciences, Inc. Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
US5231000A (en) * 1987-10-08 1993-07-27 The Mclean Hospital Antibodies to A4 amyloid peptide
US5300425A (en) * 1987-10-13 1994-04-05 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5217869A (en) * 1987-10-13 1993-06-08 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5256372A (en) * 1987-11-06 1993-10-26 Idexx Corporation Dipstick test device including a removable filter assembly
US5094941A (en) * 1987-12-31 1992-03-10 Zymogenetics, Inc. Monoclonal antibodies to PDGF
US4891313A (en) * 1988-01-21 1990-01-02 Boehringer Manheim Corporation Method for determination of a component of a sample
WO1989009393A1 (en) * 1988-03-24 1989-10-05 Igen, Inc. Luminescent chimeric proteins
US5202267A (en) * 1988-04-04 1993-04-13 Hygeia Sciences, Inc. Sol capture immunoassay kit and procedure
US6702705B1 (en) 1988-05-04 2004-03-09 Igen International, Inc. Prodrugs activated by targeted catalytic proteins
US5620845A (en) * 1988-06-06 1997-04-15 Ampcor, Inc. Immunoassay diagnostic kit
US5173399A (en) * 1988-06-10 1992-12-22 Abbott Laboratories Mouse monoclonal antibodies to hiv-1p24 and their use in diagnostic tests
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
CA1335880C (en) 1988-07-14 1995-06-13 Thomas P. O'connor Detection of an antibody and antigen in an immunoassay
US5096809A (en) * 1988-07-25 1992-03-17 Pacific Biotech, Inc. Whole blood assays using porous membrane support devices
US5059522A (en) * 1988-08-18 1991-10-22 Wayne Lawrence G Intrinsic enzyme dot blot immunoassay or indentification of microorganisms
US5030555A (en) * 1988-09-12 1991-07-09 University Of Florida Membrane-strip reagent serodiagnostic apparatus and method
DE3836348A1 (de) * 1988-10-25 1990-04-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung von fuer ein antigen klassenspezifischen antikoerpern und dazu geeignetes reagenz
EP0368674A3 (en) * 1988-11-11 1991-10-09 SANYO CHEMICAL INDUSTRIES, Ltd. Immunoassay and test kits therefor
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US6306594B1 (en) 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
US5322838A (en) * 1988-11-16 1994-06-21 Brigham & Women's Hospital Use of INHIB (the C3 β-chain) in the detection and inhibition of inflammation
US5264370A (en) * 1988-12-12 1993-11-23 Bainbridge Laboratories, Inc. Detection of basement membrane components as diagnostic of cancer and other diseases
US5512657A (en) * 1988-12-12 1996-04-30 Bainbridge Sciences, Inc. Detection of complexes which include basement membrane components as diagnostic of cancer and other diseases
CA2008304C (en) * 1989-01-31 2001-03-27 Craig S. Hill Assay for bone alkaline phosphatase
EP0456727A4 (en) * 1989-02-03 1992-01-15 Commonwealth Scientific And Industrial Research Organization Monoclonal antibodies directed against vitronectin and fibronectin, and uses thereof
US5106761A (en) * 1989-03-13 1992-04-21 International Canine Genetics, Inc. Method for detecting molecules in a liquid medium
US5599538A (en) * 1989-04-25 1997-02-04 Igen, Inc. Autoantibodies which enhance the rate of a chemical reaction
US5194585A (en) * 1989-04-25 1993-03-16 Igen, Inc. Inhibitors of catalytic antibodies
US6048717A (en) * 1989-04-25 2000-04-11 Igen International, Inc. Inhibitors of catalytic antibodies
US5658753A (en) * 1989-04-25 1997-08-19 Paul; Sudhir Catalytic antibody components
US5318897A (en) * 1989-04-25 1994-06-07 Igen, Inc. Monoclonal antibody and antibody components elicited to a polypeptide antigen ground state
US5236836A (en) * 1989-04-25 1993-08-17 Igen, Inc. Autoantibodies which enhance the rate of a chemical reaction
US6258360B1 (en) 1989-05-04 2001-07-10 Igen International, Inc. Prodrugs activated by targeted catalytic proteins
ATE130099T1 (de) * 1989-06-02 1995-11-15 Univ Georgetown Verfahren zum nachweis von antikörpern gegen streptokinase.
EP0477235B1 (en) * 1989-06-06 1998-01-07 Ampcor, Inc. Immunoassay diagnostic kit
US5187068A (en) * 1989-06-09 1993-02-16 Nicolae Luca Method for determination of lipid moiety and apolipoprotein expressed epitope immunoreactivity on intact lipoprotein
US5484735A (en) * 1989-08-23 1996-01-16 Northwestern University Immunoassay of glycosylated proteins employing antibody directed to reductively glycosylated N-terminal amino acids
US6008057A (en) * 1989-08-25 1999-12-28 Roche Diagnostics Corporation Immunoassay system
US5202264A (en) * 1989-10-27 1993-04-13 Health Research, Incorporated ELISA using multi-species antibodies for detection of von Willebrand factor in multiple species
US5196311A (en) * 1989-10-27 1993-03-23 Health Research, Incorporated Elisa test for von willebrand factor
US5830709A (en) * 1989-10-27 1998-11-03 Benson; Roger E. Detection method for homologous portions of a class of substances
EP0678744B1 (en) * 1989-11-03 1999-09-15 MORTON, Donald L. Method for detecting urinary tumor associated antigens
US5624898A (en) 1989-12-05 1997-04-29 Ramsey Foundation Method for administering neurologic agents to the brain
US6407061B1 (en) * 1989-12-05 2002-06-18 Chiron Corporation Method for administering insulin-like growth factor to the brain
US5196324A (en) * 1989-12-15 1993-03-23 Eli Lilly And Company Monoclonal antibodies reactive with a human atheroma associated antigen
KR910014706A (ko) * 1990-01-10 1991-08-31 원본미기재 세척이 필요없는 개량된 이뮤노어세이(immunoassay)장치
AU639311B2 (en) * 1990-01-26 1993-07-22 Washington Research Foundation Immune reactivity to expressed activated oncogenes for diagnosis and treatment of malignancy
US6190885B1 (en) 1990-02-02 2001-02-20 Cancer Research Fund Of Contra Costa Fusion protein containing HMFG Epitop E (S)
US5532135A (en) * 1990-02-02 1996-07-02 Cancer Research Fund Of Contra Costa Solid-phase competitive assay utilizing a fusion protein
WO1991012333A1 (fr) * 1990-02-07 1991-08-22 Kanebo, Ltd. Anticorps monoclonal antiprocollagenase et essai de depistage de procollagenase au moyen de cet anticorps
US5096837A (en) * 1990-02-08 1992-03-17 Pacific Biotech, Inc. Immunochromatographic assay and method of using same
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
US5223220A (en) * 1990-03-27 1993-06-29 Pacific Biotech, Inc. Solid phase immunoassay device and method of making same
WO1992002817A1 (en) * 1990-08-02 1992-02-20 Biocarb, Inc. Adhesion receptors for pathogenic or opportunistic microorganisms
FI922164L (fi) * 1990-09-14 1992-05-13 Biosite Diagnostics Inc Antikroppar mot komplex av ligandreceptorer och ligander och anvaendningen daerav vid bestaemning av ligandreceptorer.
JPH085920B2 (ja) * 1991-01-21 1996-01-24 富士薬品工業株式会社 抗ヒトストロムライシンモノクローナル抗体及び酵素免疫測定法
US5997878A (en) 1991-03-07 1999-12-07 Connaught Laboratories Recombinant poxvirus-cytomegalovirus, compositions and uses
AU657102B2 (en) * 1991-04-12 1995-03-02 Bio-Rad Laboratories, Inc. CA 195-like immunoreactive antigen from human amniotic fluid
US5223396A (en) * 1991-05-03 1993-06-29 Boehringer Ingelheim Pharmaceuticals, Inc. Method for detecting organ transplant rejection
WO1992020820A1 (en) * 1991-05-15 1992-11-26 Vanderbilt University Method to determine metastatic potential of tumor cells
US5869345A (en) * 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5468648A (en) * 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5607863A (en) * 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
WO1992022668A1 (en) * 1991-06-14 1992-12-23 Vanderbilt University Method and compositions to assess oxidative stress in vivo
US5338660A (en) * 1991-07-12 1994-08-16 Board Of Supervisors Of Louisiana State University And Agricutural And Mechanical College Diagnosis of Fasciola infections by detection of antigens in feces or intestinal content
ATE184703T1 (de) * 1991-07-19 1999-10-15 Cytimmune Sciences Inc Verfahren und testsatz zur messung von endogenen zytokinen
US5965379A (en) * 1991-07-19 1999-10-12 Cytimmune Sciences Inc. Method for measuring endogenous cytokines
US5726010A (en) * 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US6007999A (en) * 1991-07-31 1999-12-28 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US5369006A (en) * 1991-08-20 1994-11-29 E. I. Du Pont De Nemours And Company Determination of CK isoenzymes and CK isoforms
EP0668918A1 (en) 1991-08-28 1995-08-30 Institute Diagnostics Nichols Disease associated human autoantibodies specific for human thyroid peroxidase
DE4134297A1 (de) * 1991-10-17 1993-04-22 Behringwerke Ag Monoclonale antikoerper gegen mycoplasma pneumoniae, diese produzierende hybridome, verfahren zu deren herstellung sowie deren verwendung
DE69230502T3 (de) * 1991-10-23 2006-05-24 Thomas Jefferson University Synthese von humanen prokollagenen und kollagenen in rekombinanten dna-systemen
WO1993008473A1 (en) * 1991-10-24 1993-04-29 Beth Israel Hospital Association Assay for malignant effusions
US5525461A (en) * 1991-11-01 1996-06-11 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using total leukocyte surface antigens
AU3359493A (en) * 1992-01-17 1993-08-03 Selective Antibodies Limited Determination of haptens
DE69302719T2 (de) * 1992-02-17 1996-09-19 Akzo Nv Kalibrator und Verwendung davon in einer Immuntest
US5851787A (en) * 1992-04-20 1998-12-22 The General Hospital Corporation Nucleic acid encoding amyloid precursor-like protein and uses thereof
US5708141A (en) * 1992-05-11 1998-01-13 Corvas International, Inc. Neutrophil inhibitors
DE4218257A1 (de) * 1992-06-03 1993-12-09 Behringwerke Ag Verfahren zur immunchemischen Bestimmung eines Analyten
US5688936A (en) * 1992-06-11 1997-11-18 The Regents Of The University Of California Vesicle membrane transport proteins
US5395754A (en) * 1992-07-31 1995-03-07 Hybritech Incorporated Membrane-based immunoassay method
US5447838A (en) * 1992-08-05 1995-09-05 Hybritech Incorporated Protein-dye conjugate for confirmation of correct dilution of calibrators
US5789183A (en) * 1992-08-14 1998-08-04 University Of Arkansas Serological detection and identification of rice blast
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
AU689091B2 (en) * 1992-12-18 1998-03-26 Cell Med, Inc. Assay and treatment for demyelinating diseases such as multiple sclerosis
DE69322847T2 (de) * 1993-01-13 1999-05-27 Idemitsu Kosan Co. Ltd., Tokio/Tokyo Monoklonaler Antikörper gegen menschliches Ceruloplasmin
US5914241A (en) * 1993-01-19 1999-06-22 Biosite Diagnostics, Inc. Assays and kits for detecting analytes in the presence of cross-reacting substances
FR2700855B1 (fr) * 1993-01-28 1995-03-03 Commissariat Energie Atomique Dosage immunométrique d'un antigène ou d'un haptène.
US7713528B1 (en) 1993-02-18 2010-05-11 Enzo Therapeutics, Inc. Method for in vivo delivery of active compounds using reagent conjugate
US5374531A (en) * 1993-03-22 1994-12-20 Zynaxis, Inc. Immunoassay for determination of cells
DE4314254A1 (de) * 1993-04-30 1994-11-03 Boehringer Mannheim Gmbh Monoklonale Antikörper gegen CK-MB
CA2164725A1 (en) * 1993-06-08 1994-12-22 Alexander Saunders Two-phase optical assay method and apparatus
SG63596A1 (en) * 1993-07-29 1999-03-30 Cor Therapeutics Inc Receptor function assays
US5837546A (en) * 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
AU7732894A (en) * 1993-09-22 1995-04-10 Nichols Institute Diagnostics Graves' ophthalmopathy associated antibodies, graves' ophthalmopathy orbital antigen, and methods of use thereof
JP3356556B2 (ja) * 1993-10-22 2002-12-16 第一化学薬品株式会社 変性リポプロテイン類の測定法
US7312052B1 (en) 1993-12-08 2007-12-25 Stratagene California Polymerase compositions and uses thereof
US5695928A (en) 1993-12-10 1997-12-09 Novartis Corporation Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic reaction
US6045797A (en) * 1994-03-14 2000-04-04 New York University Medical Center Treatment or diagnosis of diseases or conditions associated with a BLM domain
US5877016A (en) 1994-03-18 1999-03-02 Genentech, Inc. Human trk receptors and neurotrophic factor inhibitors
US6040137A (en) * 1995-04-27 2000-03-21 Tripep Ab Antigen/antibody specification exchanger
US6417324B1 (en) * 2000-04-21 2002-07-09 Tripep Ab Synthetic peptides that bind to the hepatitis B virus core and e antigens
US6933366B2 (en) * 1996-12-27 2005-08-23 Tripep Ab Specificity exchangers that redirect antibodies to bacterial adhesion receptors
US6660842B1 (en) * 1994-04-28 2003-12-09 Tripep Ab Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen
US6140099A (en) * 1994-05-20 2000-10-31 The Trustees Of The University Of Pennsylvania Method of delaying fetal membrane rupture by inhibiting matrix metalloproteinase-9 activity
US5708142A (en) 1994-05-27 1998-01-13 Genentech, Inc. Tumor necrosis factor receptor-associated factors
US6107045A (en) * 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
WO1996005307A2 (en) 1994-08-12 1996-02-22 Myriad Genetics, Inc. 17q-LINKED BREAST AND OVARIAN CANCER SUSCEPTIBILITY GENE
CA2196797C (en) 1994-08-12 2000-10-10 Donna M. Shattuck-Eidens In vivo mutations and polymorphisms in the 17q-linked breast and ovarian cancer susceptibility gene
US5556752A (en) * 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US6974666B1 (en) 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US8236493B2 (en) * 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
JP2729159B2 (ja) * 1994-10-31 1998-03-18 日清製粉株式会社 ヒトグリセンチンのモノクローナル抗体、この抗体を産生するハイブリドーマおよびそれを用いるヒトグリセンチンの定量法
AU697465B2 (en) 1994-11-02 1998-10-08 Research Foundation Of The State University Of New York, The Peripheral nervous system specific sodium channels, DNA encoding therefor, crystallization, x-ray diffraction, computer molecular modeling, rational drug design, drug screening, and methods of making and using thereof
US5837815A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polypeptide products
IL114615A0 (en) 1995-07-16 1995-11-27 Yeda Res & Dev Modulators of the function of fas receptors and other proteins
US5837524A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polynucleotide products
US5807989A (en) * 1994-12-23 1998-09-15 New York University Methods for treatment or diagnosis of diseases or disorders associated with an APB domain
US6300482B1 (en) * 1995-01-03 2001-10-09 Max-Flanck-Gesellschaft Zuer For{Overscore (D)}Erung Der MDKI, a novel receptor tyrosine kinase
US5569608A (en) * 1995-01-30 1996-10-29 Bayer Corporation Quantitative detection of analytes on immunochromatographic strips
US5783387A (en) * 1995-02-06 1998-07-21 The Regents Of The University Of California Method for identifying and quantifying nucleic acid sequence aberrations
US5731153A (en) * 1996-08-26 1998-03-24 The Regents Of The University Of California Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions
US5741462A (en) * 1995-04-25 1998-04-21 Irori Remotely programmable matrices with memories
US5874214A (en) * 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US6416714B1 (en) * 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US6017496A (en) * 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US5751629A (en) * 1995-04-25 1998-05-12 Irori Remotely programmable matrices with memories
US5686257A (en) * 1995-04-26 1997-11-11 Schering Corporation Binding compositions for mammalian T cell antigens and related reagents
US6147106A (en) * 1997-08-20 2000-11-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
EP0873363B1 (en) 1995-06-14 2010-10-06 The Regents of The University of California High affinity human antibodies to tumor antigens
US5616465A (en) 1995-08-09 1997-04-01 The Regents Of The University Of California Detection and isolation of nucleic acid sequences using competitive hybridization probes
US7635597B2 (en) * 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
US6027879A (en) * 1995-08-09 2000-02-22 The Regents Of The University Of California Detection and isolation of nucleic acid sequences using a bifunctional hybridization probe
US5660990A (en) * 1995-08-18 1997-08-26 Immunivest Corporation Surface immobilization of magnetically collected materials
US5733728A (en) * 1995-08-18 1998-03-31 Regents Of The University Of Colorado Detecting and treating heart failure
US7455964B1 (en) 1996-07-15 2008-11-25 The Hospital For Sick Children Genes from the 20q13 amplicon and their uses
US6716575B2 (en) 1995-12-18 2004-04-06 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
US7119174B2 (en) * 1995-12-18 2006-10-10 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
DE69637895D1 (de) 1995-12-22 2009-05-20 Univ Utah Res Found Ein gen des "langen qt syndroms" (long qt syndrom), welches kvlqt1 kodiert und seine wechselwirkung mit mink
US7888466B2 (en) 1996-01-11 2011-02-15 Human Genome Sciences, Inc. Human G-protein chemokine receptor HSATU68
US5770086A (en) * 1996-01-25 1998-06-23 Eureka| Science Corp. Methods and apparatus using hydrogels
US5942385A (en) * 1996-03-21 1999-08-24 Sugen, Inc. Method for molecular diagnosis of tumor angiogenesis and metastasis
US6531578B1 (en) 1996-04-12 2003-03-11 Robert Webber Immunoassay method employing monoclonal antibody reactive to human iNOS
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
AU737243B2 (en) 1996-07-03 2001-08-16 Merial, Inc. Recombinant canine adenovirus (CAV) containing exogenous DNA
US6524578B1 (en) 1996-07-10 2003-02-25 Scott E. Tackett Use of nuclease to reduce wrinkles and discolorations in humans
DE19629444A1 (de) * 1996-07-22 1998-01-29 Behringwerke Ag Sensitivitätssteigerung bei der immunchemischen Bestimmung eines Analyten
US6277592B1 (en) 1996-07-31 2001-08-21 Purina Mills, Inc. Porcine leptin protein, nucleic acid sequences coding therefor and uses thereof
US6297027B1 (en) 1996-07-31 2001-10-02 Purina Mills, Inc. Bovine leptin protein, nucleic acid sequences coding therefor and uses thereof
US6159462A (en) * 1996-08-16 2000-12-12 Genentech, Inc. Uses of Wnt polypeptides
US5851984A (en) * 1996-08-16 1998-12-22 Genentech, Inc. Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
US6001658A (en) * 1996-09-13 1999-12-14 Diagnostic Chemicals Limited Test strip apparatus and method for determining presence of analyte in a fluid sample
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
CA2645721C (en) 1996-10-01 2015-05-12 Geron Corporation Human telomerase reverse transcriptase
US6004791A (en) 1996-11-13 1999-12-21 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Protein tyrosine phosphatase PTP20 and related products and methods
ES2160985T3 (es) * 1996-12-09 2001-11-16 Osteometer Biotech As Ensayos de tipo sandwich para fragmentos de colageno.
SI1019500T1 (sl) 1997-01-15 2007-02-28 Yeda Res & Dev Proteini, ki vezejo receptor 1 za ifn, dna, ki jih kodira, in postopki za regulacijo celicnega odziva na interferone
US5879951A (en) * 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
JP3394540B2 (ja) 1997-01-31 2003-04-07 ジェネンテク・インコーポレイテッド Ｏ−フコシルトランスフェラーゼ
US20040241645A1 (en) * 1997-01-31 2004-12-02 Genentech, Inc. O-fucosyltransferase
AU737406B2 (en) 1997-02-07 2001-08-16 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Activity dependent neurotrophic factor III (ADNF III)
US20050101032A1 (en) * 1997-02-10 2005-05-12 Metrika, Inc. Assay device, composition, and method of optimizing assay sensitivity
JP4245084B2 (ja) 1997-03-21 2009-03-25 ストラタジーン ポリメラーゼ増強因子（ｐｅｆ）抽出物、ｐｅｆタンパク質複合体、単離されたｐｅｆタンパク質、並びに精製及び単離方法
US5866412A (en) * 1997-03-27 1999-02-02 Millennium Pharmaceuticals, Inc. Chromosome 18 marker
US5939316A (en) * 1997-03-27 1999-08-17 Millennium Pharmaceuticals, Inc. Chromosome 18 marker
US5914394A (en) * 1997-03-27 1999-06-22 Millenium Pharmaceuticals, Inc. Methods and compositions for the diagnosis and treatment of neuropsychiatric disorders
US5955355A (en) * 1997-03-27 1999-09-21 Millennium Pharmaceuticals, Inc. Chromosome 18 marker
WO1999027098A2 (en) 1997-11-21 1999-06-03 Genentech, Inc. A-33 related antigens and their pharmacological uses
EP1787999B1 (en) 1997-04-07 2010-08-04 Genentech, Inc. Anti-VEGF antibodies
SI0973804T1 (sl) 1997-04-07 2007-06-30 Genentech Inc Proti-VEGF protitelesa
EP0994728B1 (en) 1997-04-09 2008-07-30 Intellect Neurosciences, Inc. Recombinant antibodies specific for beta-amyloid ends, dna encoding and methods of use thereof
US6818440B2 (en) * 1997-04-28 2004-11-16 Sugen, Inc. Diagnosis and treatment of alk-7 related disorders
US6103536A (en) 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
US5939252A (en) * 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US6228641B1 (en) 1997-05-20 2001-05-08 Sugen, Inc. Diagnosis and treatment of PTP04 related disorders
CA2293718A1 (en) 1997-06-10 1998-12-17 Medlyte Diagnostics, Inc. Methods for early detection of heart disease
US6342593B1 (en) 1997-06-11 2002-01-29 Sugen, Inc. Diagnosis and treatment of ALP related disorders
WO1998056892A1 (en) 1997-06-11 1998-12-17 Human Genome Sciences, Inc. Human tumor necrosis factor receptor tr9
US7115710B2 (en) * 1997-06-11 2006-10-03 Sugen, Inc. Diagnosis and treatment of PTP related disorders
US6388063B1 (en) * 1997-06-18 2002-05-14 Sugen, Inc. Diagnosis and treatment of SAD related disorders
US6235769B1 (en) 1997-07-03 2001-05-22 Sugen, Inc. Methods of preventing and treating neurological disorders with compounds that modulate the function of the C-RET receptor protein tyrosine kinase
US7087420B1 (en) 1997-07-17 2006-08-08 Cambia Microbial β-glucuronidase genes, gene products and uses thereof
US6391547B1 (en) * 1997-09-09 2002-05-21 Center For The Application Of Molecular Biology To International Agriculture Microbial β-glucuronidase genes, gene products and uses thereof
US20040067531A1 (en) * 1997-08-20 2004-04-08 Sugen, Inc. Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
US6960457B1 (en) * 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
US20140080177A1 (en) * 1997-09-26 2014-03-20 Pieris Ag Anticalins
KR20010015672A (ko) * 1997-09-29 2001-02-26 유니버시티 오브 메릴랜드, 볼티모어 악성의 생체표지로서의 변형된 ｄｎａ 신테좀 성분
EP2386629A1 (en) 1997-10-14 2011-11-16 Darwin Molecular Corporation Thymidine kinase mutants and fusion proteins having thymidine kinase and guanylate kinase activities
US6455283B1 (en) 1998-03-17 2002-09-24 Genentech, Inc. Nucleic acids encoding vascular endothelial cell growth factor-E (VEGF-E)
DK1027437T3 (da) 1997-10-29 2008-11-24 Genentech Inc Anvendelse af det WNT-1 inducerede udskilte polypeptid WISP-1
ATE409225T1 (de) 1997-10-29 2008-10-15 Genentech Inc Durch wnt-1 induzierbare gene
AU753157B2 (en) 1997-11-03 2002-10-10 Georgetown University Medical Center VEGI, an inhibitor of angiogenesis and tumor growth
US6224882B1 (en) 1997-11-07 2001-05-01 Protein Science Corp. Insect cells or fractions as adjuvant for antigens
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
US6437563B1 (en) 1997-11-21 2002-08-20 Quantum Design, Inc. Method and apparatus for making measurements of accumulations of magnetically susceptible particles combined with analytes
US6221585B1 (en) 1998-01-15 2001-04-24 Valigen, Inc. Method for identifying genes underlying defined phenotypes
US6531502B1 (en) 1998-01-21 2003-03-11 Sugen, Inc. 3-Methylidenyl-2-indolinone modulators of protein kinase
WO1999037787A2 (en) 1998-01-21 1999-07-29 Sugen, Inc. Human orthologues of wart
US6764830B1 (en) 1998-01-23 2004-07-20 The Regents Of The University Of California Thermomyces lanuginosus kinesin motor protein and methods of screening for modulators of kinesin proteins
US20040176572A1 (en) * 1998-03-16 2004-09-09 Freimer Nelson B. Methods of compositions for diagnosing and treating chromosome-18p related disorders
US6342351B1 (en) 1998-03-16 2002-01-29 Millennium Pharmaceuticals, Inc. Methods and compositions for diagnosing and treating chromosome-18p related disorders
US6274314B1 (en) * 1998-04-02 2001-08-14 Nyxis Neurotherapies, Inc. Diagnostic assay for the modified nucleosides pseudouridine, 7-methyladenosine, or 1-methyladenosine
US6514981B1 (en) * 1998-04-02 2003-02-04 Sugen, Inc. Methods of modulating tyrosine protein kinase function with indolinone compounds
AU3642499A (en) 1998-04-14 1999-11-01 Sugen, Inc. Ste20-related protein kinases
US7157083B2 (en) * 1998-04-17 2007-01-02 Surrogate Pharmaceutical Pathways, Llc Compositions and methods for treating retroviral infections
US20060019404A1 (en) * 1998-05-06 2006-01-26 Blatt Joel M Quantitative assay with extended dynamic range
CN1307473A (zh) 1998-05-19 2001-08-08 研究发展基金会 三萜组合物和它们的使用方法
EP1086231A2 (en) 1998-06-12 2001-03-28 Henry M. Jackson Foundation For The Advancement Of Military Medicine ENHANCEMENT OF B CELL ACTIVATION AND IMMUNOGLOBULIN SECRETION BY CO-STIMULATION OF RECEPTORS FOR ANTIGEN AND EBV Gp350/220
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
EP1806362B1 (en) 1998-07-28 2010-07-21 The Regents of the University of California Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
NZ510497A (en) * 1998-08-21 2003-09-26 Immunex Corp Human IL-1 epsilon DNA and polypeptides
WO2000014200A2 (en) 1998-09-09 2000-03-16 Millennium Pharmaceuticals, Inc. Essential bacterial genes and their use
US20070178475A1 (en) * 1998-09-17 2007-08-02 Nehls Michael C Novel human polynucleotides and polypeptides encoded thereby
US6680335B2 (en) 1998-09-28 2004-01-20 Sugen, Inc. Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
US6368793B1 (en) * 1998-10-14 2002-04-09 Microgenomics, Inc. Metabolic selection methods
US7091324B2 (en) 1998-11-05 2006-08-15 Board Of Trustees Of Leland Stanford Junior University Prevention and treatment of HCV infection employing antibodies directed against conformational epitopes
SI1135498T1 (sl) 1998-11-18 2008-06-30 Genentech Inc Variante protitelesa z višjo vezavno afiniteto vprimerjavi z izvirnimi protitelesi
ATE338120T2 (de) 1998-11-27 2006-09-15 Ucb Sa Zusammensetzungen und verfahren zur erhöhung der knochenmineralisierung
US20040009535A1 (en) 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
US7273618B2 (en) * 1998-12-09 2007-09-25 Chiron Corporation Method for administering agents to the central nervous system
WO2000037502A2 (en) 1998-12-22 2000-06-29 Genentech, Inc. Vascular endothelial cell growth factor antagonists and uses thereof
US6861442B1 (en) 1998-12-30 2005-03-01 Sugen, Inc. PYK2 and inflammation
US20020164784A1 (en) * 2000-10-27 2002-11-07 Walke D. Wade Novel human 7TM proteins and polynucleotides encoding the same
US20020031802A1 (en) * 2000-05-12 2002-03-14 Yi Hu Novel seven transmembrane proteins and polynucleotides encoding the same
US20020061556A1 (en) * 2000-04-27 2002-05-23 Walke D. Wade Novel membrane proteins and polynucleotides encoding the same
US6570003B1 (en) * 2001-01-09 2003-05-27 Lexion Genetics Incorporated Human 7TM proteins and polynucleotides encoding the same
AU777909B2 (en) 1999-01-19 2004-11-04 Lexicon Genetics Incorporated Mammalian cortexin-like proteins and polynucleotides encoding the same
US7625859B1 (en) * 2000-02-16 2009-12-01 Oregon Health & Science University HER-2 binding antagonists
US7393823B1 (en) 1999-01-20 2008-07-01 Oregon Health And Science University HER-2 binding antagonists
US7396810B1 (en) * 2000-08-14 2008-07-08 Oregon Health Sciences University Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
US6303749B1 (en) 1999-01-29 2001-10-16 Amgen Inc. Agouti and agouti-related peptide analogs
US6403784B1 (en) 1999-02-09 2002-06-11 Lexicon Genetics Incorporated Human uncoupling proteins and polynucleotides encoding the same
GB9903841D0 (en) * 1999-02-20 1999-04-14 Imp College Innovations Ltd Diagnosis and treatment of cancer
US6864235B1 (en) * 1999-04-01 2005-03-08 Eva A. Turley Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans
US6911429B2 (en) * 1999-04-01 2005-06-28 Transition Therapeutics Inc. Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans
AU773675B2 (en) 1999-04-12 2004-06-03 Dainippon Sumitomo Pharma Co., Ltd. Method for analyzing the amount of intraabdominal adipose tissue
US20080145347A1 (en) * 1999-04-29 2008-06-19 Steiner Mitchell S p-Hyde sequences in the Rat
US20020110809A1 (en) * 1999-04-30 2002-08-15 Nehls Michael C. Novel human polynucleotides and polypeptides encoded thereby
US7566452B1 (en) 1999-05-04 2009-07-28 New York University Cancer treatment with endothelin receptor antagonists
US20020095031A1 (en) * 1999-05-04 2002-07-18 Nehls Michael C. Novel human polynucleotides and polypeptides encoded thereby
US20030186311A1 (en) * 1999-05-21 2003-10-02 Bioforce Nanosciences, Inc. Parallel analysis of molecular interactions
IL130225A0 (en) 1999-05-31 2000-06-01 Yissum Res Dev Co Novel uses of antibodies against ache and peptides thereof
CA2382765A1 (en) * 1999-08-24 2001-03-01 Lexicon Genetics Incorporated Sequence derived from a human mammary gland cdna library
KR100510795B1 (en) * 1999-08-31 2005-08-30 Compositions and Methods for the Treatment of Tumor
US20080003673A1 (en) * 1999-09-02 2008-01-03 Alejandro Abuin Novel human proteases and polynucleotides encoding the same
US6448388B1 (en) 2000-08-16 2002-09-10 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
US7374933B2 (en) * 2000-04-12 2008-05-20 Lexicon Pharmaceuticals, Inc. Human metalloprotease and polynucleotides encoding the same
US20050153323A1 (en) * 2000-07-28 2005-07-14 Yi Hu Novel human proteases and polynucleotides encoding the same
US20020165376A1 (en) * 1999-12-22 2002-11-07 Walke D. Wade Novel human proteases and polynucleotides encoding the same
US6433153B1 (en) 1999-09-02 2002-08-13 Lexicon Genetics Incorporated Human calcium dependent proteases and polynucleotides encoding the same
US20030050464A1 (en) * 2000-07-28 2003-03-13 Yi Hu Novel human proteases and polynucleotides encoding the same
US6716614B1 (en) 1999-09-02 2004-04-06 Lexicon Genetics Incorporated Human calcium dependent proteases, polynucleotides encoding the same, and uses thereof
US7459540B1 (en) 1999-09-07 2008-12-02 Amgen Inc. Fibroblast growth factor-like polypeptides
US7408047B1 (en) * 1999-09-07 2008-08-05 Amgen Inc. Fibroblast growth factor-like polypeptides
CA2384663A1 (en) * 1999-09-08 2001-03-15 Lexicon Genetics Incorporated Human g-protein coupled 7 transmembrane receptor and polynucleotides encoding the same
EP1425578A2 (en) 1999-09-13 2004-06-09 Equitech Laboratories, Inc. Materials and methods for the determination of an analyte
US6900043B1 (en) 1999-09-21 2005-05-31 Amgen Inc. Phosphatases which activate map kinase pathways
AU783897B2 (en) * 1999-09-24 2005-12-22 Lexicon Genetics Incorporated Novel human protease inhibitor-like proteins and polynucleotides encoding the same
US6867291B1 (en) * 2000-09-15 2005-03-15 Lexicon Genetics Incorporated Human hemicentin proteins and polynucleotides encoding the same
US20030028907A1 (en) * 2001-07-03 2003-02-06 Walke D. Wade Novel human kielin-like proteins and polynucleotides encoding the same
CA2385813A1 (en) * 1999-09-24 2001-03-29 Lexicon Genetics Incorporated Human endothelin converting enzyme-like proteins and polynucleotides encoding the same
US6790660B1 (en) * 2001-09-18 2004-09-14 Lexicon Genetics Incorporated Human kielin-like proteins and polynucleotides encoding the same
US20080050809A1 (en) * 1999-09-28 2008-02-28 Alejandro Abuin Novel human kinases and polynucleotides encoding the same
US6716616B1 (en) 1999-09-28 2004-04-06 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
US6777545B2 (en) * 2001-04-06 2004-08-17 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6797510B1 (en) * 2001-05-24 2004-09-28 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6511840B1 (en) 2000-06-15 2003-01-28 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
US6759527B2 (en) 2001-03-20 2004-07-06 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
US6841377B1 (en) * 2001-06-13 2005-01-11 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
US6720173B1 (en) 1999-11-08 2004-04-13 Lexicon Genetics Incorporated Human kinase protein and polynucleotides encoding the same
US6541252B1 (en) 2000-05-19 2003-04-01 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6734009B2 (en) 2000-12-27 2004-05-11 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6586230B1 (en) * 2000-10-27 2003-07-01 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
EP1220932B1 (en) * 1999-09-29 2005-11-09 Lexicon Genetics Incorporated Human carboxypeptidases and polynucleotides encoding the same
US6794132B2 (en) 1999-10-02 2004-09-21 Biosite, Inc. Human antibodies
US7135287B1 (en) 1999-10-02 2006-11-14 Biosite, Inc. Human antibodies
US20070111259A1 (en) * 1999-10-02 2007-05-17 Medarex, Inc. Human antibodies
WO2001027274A1 (en) 1999-10-12 2001-04-19 Lexicon Genetics Incorporated Human ldl receptor family proteins and polynucleotides encoding the same
AU1198701A (en) * 1999-10-13 2001-04-23 Lexicon Genetics Incorporated Novel human membrane proteins
DE60039708D1 (de) * 1999-10-18 2008-09-11 Lexicon Pharmaceuticals Inc Menschliches chordin und polynukleotiden die dafür kodieren
US6815538B2 (en) * 2000-03-20 2004-11-09 Lexicon Genetics Incorporated Human secreted proteins and polynucleotides encoding the same
US6750054B2 (en) 2000-05-18 2004-06-15 Lexicon Genetics Incorporated Human semaphorin homologs and polynucleotides encoding the same
US6743907B1 (en) * 1999-10-19 2004-06-01 Lexicon Genetics Incorporated Human proteins and polynucleotides encoding the same
US20080213878A1 (en) * 1999-10-19 2008-09-04 Gregory Donoho Novel human membrane proteins and polynucleotides encoding the same
US7268222B1 (en) 1999-11-02 2007-09-11 Lexicon Pharmaceuticals, Inc. Polynucleotides encoding human transporter proteins
EP1230366A2 (en) * 1999-11-10 2002-08-14 Lexicon Genetics Incorporated Human atpases and polynucleotides encoding the same
EP1242588A2 (en) 1999-11-12 2002-09-25 Lexicon Genetics Incorporated Human proteins with homology to carboxypeptidases and polynucleotides encoding the same
CN100399030C (zh) 1999-11-16 2008-07-02 杰南技术公司 用于vegf的elisa
US6943010B1 (en) 1999-11-19 2005-09-13 Hortense W. Dodo Down-regulation and silencing of allergen genes in transgenic peanut seeds
PT1234031T (pt) 1999-11-30 2017-06-26 Mayo Foundation B7-h1, uma nova molécula imunoregulatória
US6680209B1 (en) * 1999-12-06 2004-01-20 Biosite, Incorporated Human antibodies as diagnostic reagents
EP1244694A2 (en) * 1999-12-07 2002-10-02 Lexicon Genetics Incorporated Putative human g-protein coupled receptors
EP1240187A2 (en) * 1999-12-07 2002-09-18 Lexicon Genetics Incorporated Novel human kinase proteins and polynucleotides encoding the same
CA2393723A1 (en) * 1999-12-09 2001-06-14 Lexicon Genetics Incorporated Human adam-ts proteases and polynucleotides encoding the same
WO2001042477A1 (en) * 1999-12-13 2001-06-14 Lexicon Genetics Incorporated Novel human transferase proteins and polynucleotides encoding the same
JP2003529341A (ja) * 1999-12-22 2003-10-07 レキシコン・ジェネティクス・インコーポレーテッド ヒト膜タンパクおよびそれをコードするポリヌクレオチド
WO2001045689A2 (en) 1999-12-22 2001-06-28 Sugen, Inc. Indolinone derivatives for modulation of c-kit tyrosine protein kinase
EP1897946B1 (en) 1999-12-23 2012-07-11 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
CA2402360A1 (en) * 2000-01-06 2001-07-12 Lexicon Genetics Incorporated Novel human proteases and polynucleotides encoding the same
WO2001053493A2 (en) * 2000-01-18 2001-07-26 Lexicon Genetics Incorporated Human kinase protein and polynucleotides encoding the same
AU2001253117B8 (en) * 2000-01-26 2006-08-03 Lexicon Pharmaceuticals, Inc. Human neurexin-like proteins and polynucleotides encoding the same
EP1301600A2 (en) * 2000-01-28 2003-04-16 Lexicon Genetics Incorporated Human enzymes and polynucleotides encoding the same
JP2003520607A (ja) * 2000-01-28 2003-07-08 レキシコン・ジェネティクス・インコーポレーテッド ヒト膜タンパクおよびそれをコードするポリヌクレオチド
AU782817B2 (en) * 2000-02-04 2005-09-01 Lexicon Pharmaceuticals, Inc. Novel human G protein coupled receptor proteins and polynucleotides encoding the same
WO2001057220A2 (en) * 2000-02-04 2001-08-09 Lexicon Genetics Incorporated Human enzymes and polynucleotides encoding the same
AU3690801A (en) 2000-02-11 2001-08-20 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
EA005996B1 (ru) * 2000-02-15 2005-08-25 Сьюджен, Инк. Пирролзамещенный 2-индолинон, фармацевтическая композиция (варианты), способ модулирования каталитической активности протеинкиназы, способ лечения или профилактики нарушения в организме, связанного с протеинкиназой
AU2001238503A1 (en) * 2000-02-17 2001-08-27 Lexicon Genetics Incorporated Novel human thrombospondin repeat proteins and polynucleotides encoding the same
AU2001245370A1 (en) * 2000-02-29 2001-09-12 Lexicon Genetics Incorporated Novel human transferase proteins and polynucleotides encoding the same
CA2401645A1 (en) * 2000-02-29 2001-09-07 Lexicon Genetics Incorporated Novel human transporter proteins and polynucleotides encoding the same
US20040002068A1 (en) 2000-03-01 2004-01-01 Corixa Corporation Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
AU2001247283A1 (en) * 2000-03-06 2001-09-17 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
AU4352101A (en) * 2000-03-10 2001-09-24 Lexicon Genetics Inc Novel human g-coupled protein receptor kinases and polynucleotides encoding the same
CA2402936A1 (en) * 2000-03-13 2001-09-20 Lexicon Genetics Incorporated Human phospholipases and polynucleotides encoding the same
WO2001071352A2 (en) * 2000-03-17 2001-09-27 The Salk Institute For Biological Studies Compositions associated with complex formation
AU2001218871A1 (en) * 2000-03-21 2001-10-03 Takao Arai Monoclonal antibody and method and kit for the immunoassay of soluble human st2 with the use of the same
US7514239B2 (en) 2000-03-28 2009-04-07 Amgen Inc. Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
WO2001074404A2 (en) 2000-03-31 2001-10-11 Novarx Compositions containing genetically modified lung cancer cells expressing a tgf-beta inhibitor
CA2404896A1 (en) * 2000-04-03 2001-10-11 Lexicon Genetics Incorporated Human ion channel protein and polynucleotides encoding the same
US7364867B2 (en) * 2000-04-17 2008-04-29 The Mount Sinai School Of Medicine Method of identifying bitter compounds by employing TRP8, a transient receptor potential channel expressed in taste receptor cells
AU5719501A (en) 2000-04-25 2001-11-07 Lexicon Genetics Inc Novel human kinase proteins and polynucleotides encoding the same
US7030219B2 (en) * 2000-04-28 2006-04-18 Johns Hopkins University B7-DC, Dendritic cell co-stimulatory molecules
DK1287364T3 (da) 2000-04-29 2009-03-02 Univ Iowa Res Found Diagnostisk og terapi til makulære degenerationsrelaterede lidelser
JP2003533205A (ja) * 2000-05-12 2003-11-11 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトリポカリン相同体およびそれをコードするポリヌクレオチド
WO2001087238A2 (en) * 2000-05-17 2001-11-22 Oregon Health & Sciences University Induction of apoptosis and cell growth inhibition by protein 4.33
WO2001090179A2 (en) * 2000-05-23 2001-11-29 Lexicon Genetics Incorporated Novel human thrombospondin-like proteins and polynucleotides encoding the same
US6790667B1 (en) 2000-05-30 2004-09-14 Lexicon Genetics Incorporated Human mitochondrial proteins and polynucleotides encoding the same
US6703495B2 (en) * 2000-06-07 2004-03-09 Lexicon Genetics Incorporated Polynucleotides encoding human transporter protein
US6465632B1 (en) 2000-06-09 2002-10-15 Lexicon Genetics Incorporated Human phosphatases and polynucleotides encoding the same
AU2001266844A1 (en) * 2000-06-09 2001-12-17 Lexicon Genetics Incorporated Novel human seven transmembrane proteins and polynucleotides encoding the same
US20040168209A1 (en) * 2000-06-12 2004-08-26 Alejandro Abuin Novel murine polynucleotide sequences and mutant cells and mutant animals defined thereby
EP1294949A4 (en) 2000-06-15 2004-08-25 Human Genome Sciences Inc HUMAN TUMORNESCROSE FACTOR DELTA AND EPSILON
ES2444710T3 (es) 2000-06-22 2014-02-26 Amgen, Inc. Uso de un anticuerpo específico para un polipéptido similar a IL-17
EP2042597B1 (en) 2000-06-23 2014-05-07 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
EP2077276A1 (en) 2000-06-23 2009-07-08 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogensis
US20030032791A1 (en) * 2000-06-26 2003-02-13 Alan Robertson Scott Novel melanocortin-4 receptor sequences and screening assays to identify compounds useful in regulating animal appetite and metabolic rate
US6528321B1 (en) 2000-06-26 2003-03-04 Beckman Coulter, Inc. Opposable-element chromatographic assay device for detection of analytes in whole blood samples
US7074591B2 (en) * 2000-06-27 2006-07-11 Lexicon Genetics Incorporated Polynucleotides encoding human GABA receptors
US20060034828A1 (en) * 2000-06-28 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a GlcNAcMAN5GLCNAC2 glycoform
US20060024304A1 (en) * 2000-06-28 2006-02-02 Gerngross Tillman U Immunoglobulins comprising predominantly a Man5GlcNAc2 glycoform
US20060034830A1 (en) * 2000-06-28 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a GalGlcNAcMan5GLcNAc2 glycoform
US20060029604A1 (en) * 2000-06-28 2006-02-09 Gerngross Tillman U Immunoglobulins comprising predominantly a GlcNAc2Man3GlcNAc2 glycoform
MXPA02012747A (es) 2000-06-28 2003-09-25 Amgen Inc Moleculas del receptor de linfopoietina estromica timica y sus usos.
US20060257399A1 (en) * 2000-06-28 2006-11-16 Glycofi, Inc. Immunoglobulins comprising predominantly a Man5GIcNAc2 glycoform
JP2004515220A (ja) * 2000-07-21 2004-05-27 インサイト・ゲノミックス・インコーポレイテッド プロテアーゼ
US6632681B1 (en) 2000-07-24 2003-10-14 Ey Laboratories Reagent delivery device and method of use
US6887685B1 (en) * 2000-07-25 2005-05-03 Lexicon Genetics Incorporated Human thymosin protein and polynucleotides encoding the same
US20020076780A1 (en) * 2000-08-16 2002-06-20 Turner C. Alexander Novel human ion channel proteins and polynucleotides encoding the same
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6858590B2 (en) * 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
KR100801123B1 (ko) 2000-08-17 2008-02-05 트리펩 아베 리바비린 함유 백신 및 이것의 사용 방법
US6680059B2 (en) * 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
EP1311690B1 (en) * 2000-08-22 2006-07-26 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
JP2004506447A (ja) * 2000-08-22 2004-03-04 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒト７ｔｍタンパクおよびそれをコードするポリヌクレオチド
JP2003000268A (ja) * 2000-08-25 2003-01-07 Pfizer Prod Inc 血管新生にかかわる疾患を診断および治療するための方法および組成物
AU2001288478B2 (en) 2000-08-25 2006-11-02 Basf Plant Science Gmbh Plant polynucleotides encoding prenyl proteases
EP1197550A3 (en) * 2000-08-25 2002-11-20 Pfizer Products Inc. Methods and compositions for diagnosing and treating disorders involving angiogenesis
WO2002018555A2 (en) * 2000-08-31 2002-03-07 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
US7229790B2 (en) * 2000-09-01 2007-06-12 Lexicon Pharmaceuticals, Inc. Human GABA transporter protein and polynucleotides encoding the same
AU2001288436A1 (en) * 2000-09-01 2002-03-22 International Bioimmune Systems, Inc The identification and development of specific monoclonal antibodies to squamous cell carcinoma
US20030176344A1 (en) * 2000-09-14 2003-09-18 Decode Genetics Ehf. Human osteoporosis gene
US7186521B2 (en) * 2000-09-25 2007-03-06 The Regents Of The University Of California Determining the effect of a substance on sequestration, uptake, and accumulation of amyloid in brain cells
DE60119757T2 (de) 2000-09-27 2007-04-26 Lexicon Genetics Inc., The Woodlands Menschliche ionenaustauschproteine und dafür kodierende polynukleotiden
AU2001293084A1 (en) * 2000-09-27 2002-04-08 Lexicon Genetics Incorporated Human protease inhibitor proteins and polynucleotides encoding the same
US6777232B1 (en) * 2000-10-02 2004-08-17 Lexicon Genetics Incorporated Human membrane proteins and polynucleotides encoding the same
AU2002230390A1 (en) * 2000-10-05 2002-04-29 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Ixodes scapularis tissue factor pathway inhibitor
AU2002213183A1 (en) 2000-10-12 2002-04-22 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
ATE316653T1 (de) * 2000-10-17 2006-02-15 Besst Test Aps Test zum direkten nachweis eines inflammatorischen anzeiger in einer körperflüssigkeitsprobe
US7001763B1 (en) 2000-10-17 2006-02-21 Lexicon Genetics Incorporated Human semaphorin proteins and polynucleotides encoding the same
AU2002232593A1 (en) * 2000-10-27 2002-05-06 Oregon Health And Science University Novel mutant igbp-3 molecules that do not bind to igfs, but retain their ability to functionally bind igfbp-3 receptor
JP2004531209A (ja) * 2000-10-30 2004-10-14 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒト７ｔｍタンパクおよびそれをコードするポリヌクレオチド
CA2427828A1 (en) * 2000-11-01 2002-05-10 Lexicon Genetics Incorporated Novel human proteases and polynucleotides encoding the same
JP2004535154A (ja) * 2000-11-15 2004-11-25 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒト分泌タンパク質およびそれをコードするポリヌクレオチド
US20060148732A1 (en) * 2000-11-17 2006-07-06 Gutterman Jordan U Inhibition of NF-kappaB by triterpene compositions
WO2002042438A2 (en) 2000-11-20 2002-05-30 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6989247B2 (en) 2000-11-28 2006-01-24 Celltech R & D, Inc. Compositions and methods for diagnosing or treating psoriasis
US7393921B2 (en) * 2000-12-04 2008-07-01 Institute For Systems Biology Prostate-specific polypeptide pamp and encoding nucleic acid molecules
US9249229B2 (en) * 2000-12-08 2016-02-02 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US20040198661A1 (en) * 2000-12-08 2004-10-07 Bowdish Katherine S. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
EP1341902A2 (en) * 2000-12-08 2003-09-10 Alexion Pharmaceuticals, Inc. Chronic lymphocytic leukemia cell line and its use for producing an antibody
US7408041B2 (en) * 2000-12-08 2008-08-05 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US20060057651A1 (en) 2000-12-08 2006-03-16 Bowdish Katherine S Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
JP2004517622A (ja) 2000-12-11 2004-06-17 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼ及び該キナーゼをコードするポリヌクレオチド
CA2431210A1 (en) * 2000-12-12 2002-06-20 Lexicon Genetics Incorporated Novel human kinases and uses thereof
US6583269B1 (en) 2000-12-18 2003-06-24 Lexicon Genetics Incorporated Human protease inhibitor and polynucleotides encoding the same
JP2005502307A (ja) * 2000-12-20 2005-01-27 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトイオンチャンネルタンパクおよびそれをコードするポリヌクレオチド
US6852844B1 (en) * 2000-12-20 2005-02-08 Lexicon Genetics Incorporated Human protocadherin proteins and polynucleotides encoding the same
IL140537A0 (en) * 2000-12-25 2002-02-10 Hadasit Med Res Service Educated nk t cells and their uses in the treatment of immune-related disorders
US7445802B2 (en) * 2000-12-26 2008-11-04 Yeda Research And Development Co. Ltd Site-specific in situ generation of allicin using a targeted alliinase delivery system for the treatment of cancers, tumors, infectious diseases and other allicin-sensitive diseases
AU2001297533A1 (en) * 2000-12-28 2002-09-12 Lexicon Genetics Incorporated Novel human ion channel-related proteins and polynucleotides encoding the same
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US20020115844A1 (en) * 2001-01-05 2002-08-22 Yu Xuanchuan Sean Novel human lipase and polynucleotides encoding the same
AU2002236717A1 (en) * 2001-01-08 2002-07-16 Lexicon Genetics Incorporated Human protease and polynucleotides encoding the same
JP2004524835A (ja) * 2001-01-23 2004-08-19 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼおよびそれをコードするポリヌクレオチド
JP2005502311A (ja) * 2001-01-24 2005-01-27 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトリパーゼ及び該リパーゼをコードするポリヌクレオチド
US20020127674A1 (en) * 2001-02-02 2002-09-12 Xuanchuan Yu Novel human transporter protein and polynucleotides encoding the same
NZ541541A (en) 2001-02-14 2007-04-27 Anthrogenesis Corp A composition suitable for transplantation which comprises a population of hematopoietic stem cells comprising placental stem cells that are CD34+ and CD38-
AR042586A1 (es) * 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
CA2473197A1 (en) * 2001-02-20 2002-08-29 Lexicon Genetics Incorporated Novel human protease and polynucleotides encoding the same
US20020117169A1 (en) 2001-02-27 2002-08-29 Kurz Daniel R. Cover and applicator for a portion of a mammalian body
JP3929250B2 (ja) * 2001-03-08 2007-06-13 株式会社ルネサステクノロジ 半導体装置
AU2002306696B2 (en) * 2001-03-12 2007-12-20 Lexicon Pharmaceuticals, Inc. Novel human EGF-family proteins and polynucleotides encoding the same
WO2002072603A2 (en) * 2001-03-12 2002-09-19 Lexicon Genetics Incorporated Novel human dectin proteins and polynucleotides encoding the same
AU2002252296A1 (en) * 2001-03-12 2002-09-24 Lexicon Genetics Incorporated Novel human transporter proteins and polynucleotides encoding the same
CA2441042A1 (en) * 2001-03-15 2002-09-26 International Bioimmune Systems, Inc. Monoclonal antibody therapy for pancreas cancer
US6994995B1 (en) 2001-03-16 2006-02-07 Lexicon Genetics Incorporated Human synaptotagmin and polynucleotides encoding the same
US20030228639A1 (en) * 2001-03-19 2003-12-11 Wright George L Prostate cancer markers
US6613534B2 (en) 2001-03-20 2003-09-02 Wake Forest University Health Sciences MAP-2 as a determinant of metastatic potential
US7071303B2 (en) * 2001-03-28 2006-07-04 Institute For Systems Biology Androgen regulated prostate specific nucleic acids
EP1383880A1 (en) * 2001-04-06 2004-01-28 Lexicon Genetics Incorporated Novel human kinase and polynucleotides encoding the same
EP1377680B1 (en) 2001-04-12 2011-10-05 Imperial Innovations Limited Diagnosis and treatment of breast cancer based upon scn5a
US20070128229A1 (en) * 2002-04-12 2007-06-07 Wyeth Surface proteins of Streptococcus pyogenes
BR0208874A (pt) * 2001-04-13 2004-06-22 Wyeth Corp Proteìnas superficiais de streptococcus pyogenes
US6607895B2 (en) 2001-04-16 2003-08-19 Lexicon Genetics Incorporated Human adenylsuccinate synthetase and polynucleotides encoding the same
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
EP1572871A4 (en) * 2001-04-20 2007-11-14 Sinai School Medicine T1R3, A NEW TASTE RECEPTOR
AU2002259011A1 (en) * 2001-04-30 2002-11-11 Lexicon Genetics Incorporated Novel human nuclear transporters and polynucleotides encoding the same
US20030211464A1 (en) * 2001-05-02 2003-11-13 Charles Pidgeon Method and compositions for drug discovery
ATE405586T1 (de) 2001-05-08 2008-09-15 Darwin Molecular Corp Verfahren zur regulierung der immunfunktion in primaten unter verwendung des foxp3-proteins
WO2002090517A2 (en) * 2001-05-09 2002-11-14 Lexicon Genetics Incorporated Novel human kinases and polynucleotides encoding the same
US20020193585A1 (en) * 2001-05-25 2002-12-19 Walke D. Wade Novel human transporter proteins and polynucleotides encoding the same
CA2448347C (en) 2001-05-29 2010-09-21 Lexicon Genetics Incorporated Novel human hydroxylases and polynucleotides encoding the same
MXPA03010804A (es) 2001-06-01 2004-11-22 Cornell Res Foundation Inc Anticuerpos modificados para antigeno de membrana especifico de la prostata y usos de los mismos.
US20070160576A1 (en) 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
US7026121B1 (en) * 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US7235358B2 (en) * 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US20030027301A1 (en) * 2001-06-14 2003-02-06 Yi Hu Novel human transporter proteins and polynucleotides encoding the same
EP1423428B2 (en) * 2001-06-20 2012-11-14 Fibron Ltd. Antibodies that block fgfr3 activation, methods of screening for and uses thereof
US20020197694A1 (en) * 2001-06-20 2002-12-26 Weiping Shao Conjugates of reduced antibodies and biomolecules
US20030018009A1 (en) * 2001-06-20 2003-01-23 Collins Douglas A. Adenosyl-cobalamin fortified compositions
AU2002326315B2 (en) 2001-06-26 2007-07-05 Senomyx, Inc. T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7300633B2 (en) * 2001-07-25 2007-11-27 Oakville Hong Kong Company Limited Specimen collection container
JP4265149B2 (ja) * 2001-07-25 2009-05-20 セイコーエプソン株式会社 電気光学装置、電気光学装置の製造方法
US7270959B2 (en) 2001-07-25 2007-09-18 Oakville Hong Kong Company Limited Specimen collection container
AUPR673001A0 (en) 2001-07-31 2001-08-23 Prince Henry's Institute Of Medical Research Pregnancy-related enzyme activity
US7744888B2 (en) 2001-08-03 2010-06-29 Abgenomics Cooperatief U.A. Methods of modulating T cell or natural killer cell activity with anti-P-selectin glycoprotein ligand 1 antibodies
AU2002365248A1 (en) 2001-08-09 2003-09-02 Cornell Research Foundation, Inc. Detection of bovine viral diarrhea virus in hair samples
WO2003016481A2 (en) * 2001-08-14 2003-02-27 Lexicon Genetics Incorporated Novel human collagen proteins and polynucleotides encoding the same
WO2003018769A2 (en) * 2001-08-27 2003-03-06 Tularik Inc. Amplified gene involved in cancer
EP1423427A2 (en) * 2001-08-27 2004-06-02 Novartis AG Nogo receptor homologues and their use
CA2459183A1 (en) * 2001-08-27 2003-03-06 Tularik Inc. Amplified oncogenes and their involvement in cancer
JP2003076656A (ja) * 2001-09-05 2003-03-14 Sony Corp 情報処理システム、情報処理装置および方法、記録媒体、並びにプログラム
WO2003024308A2 (en) 2001-09-18 2003-03-27 Fibrogen, Inc. Methods of assaying connective tissue growth factor
ATE443259T1 (de) 2001-09-20 2009-10-15 Univ Texas Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper- komplexe mit elisa-tests
ES2559668T3 (es) * 2001-09-27 2016-02-15 Gangagen, Inc. Bacteriófagos deficientes en lisina, que tienen inmunogenicidad reducida
EP1437936A4 (en) 2001-09-27 2005-10-12 Pioneer Hi Bred Int PHYTATE POLYNUCLEOTIDES AND METHOD FOR THEIR USE
CA2461710C (en) * 2001-09-27 2013-01-15 Gangagen, Inc. Incapacitated whole-cell immunogenic bacterial compositions
US20030110518A1 (en) * 2001-09-28 2003-06-12 Houseknecht Karen L. Melanocortin-5 receptor sequences and uses thereof
US7393696B2 (en) * 2001-09-28 2008-07-01 Aspenbio Pharma, Inc. Bovine pregnancy test
AU2002340118B2 (en) 2001-10-04 2007-09-13 Immunex Corporation UL16 Binding protein 4
EP1434774A1 (en) 2001-10-10 2004-07-07 Sugen, Inc. 3-(4-substituted heterocyclyl)-pyrrol-2-ylmethylidene)-2-indolinone derivatives as protein kinase inhibitors
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
DE10151511A1 (de) 2001-10-18 2003-05-08 Basf Lynx Bioscience Ag ee3-Proteinfamilie und zugrundeliegende DNA-Sequenzen
JP2005519584A (ja) * 2001-10-22 2005-07-07 ノバルティス アクチエンゲゼルシャフト Ｎｏｇｏレセプターホモログおよびそれらの使用
GB0126378D0 (en) 2001-11-02 2002-01-02 Oxford Biomedica Ltd Antigen
WO2003051174A2 (en) * 2001-11-09 2003-06-26 Neurogenetics, Inc. Single nucleotide polymorphisms and mutations on alpha-2-macroglobulin
WO2003039600A1 (en) * 2001-11-09 2003-05-15 Neopharm, Inc. Selective treatment of il-13 expressing tumors
US20040067512A1 (en) * 2001-11-09 2004-04-08 Neurogenetics, Inc. Single nucleotide polymorphisms and mutations on Alpha-2-Macroglobulin
WO2003044161A2 (en) * 2001-11-15 2003-05-30 Tularik Inc. Gene amplification and overexpression in cancer
US20030099621A1 (en) 2001-11-29 2003-05-29 Robert Chow Stem cell screening and transplantation therapy for HIV infection
AU2002348131A1 (en) 2001-12-05 2003-06-23 Baylor College Of Medicine Methods and compositions for control of bone formation via modulation of sympathetic tone
WO2003054226A2 (en) * 2001-12-10 2003-07-03 Novartis Ag Methods of treating psychosis and schizophrenia based on a polymorphism in the ctf gene
AU2002359697A1 (en) * 2001-12-20 2003-07-09 Tularik Inc. Identification of an amplified gene and target for drug intervention
US20060034829A1 (en) * 2001-12-27 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a MAN3GLCNAC2 glycoform
US20060024292A1 (en) * 2001-12-27 2006-02-02 Gerngross Tillman U Immunoglobulins comprising predominantly a Gal2GlcNAc2Man3GlcNAc2 glycoform
US20040137440A1 (en) * 2002-01-15 2004-07-15 Biaoyang Lin Androgen regulated nucleic acid molecules and encoded proteins
US7462491B2 (en) * 2002-01-31 2008-12-09 Baylor College Of Medicine Methods and compositions for diagnosis and monitoring of prostate cancer progression by detection of serum caveolin
US7704700B2 (en) * 2002-02-12 2010-04-27 Burnham Institute For Medical Research Methods for determining the prognosis for patients with a prostate neoplastic condition using inhibitor of apoptosis polypeptides
ATE524739T1 (de) 2002-02-13 2011-09-15 American Diagnostica Inc Verfahren zur auswahl von behandlungsschemata und vorhersage von behandlungsresultaten bei krebspatienten
EP1485461A4 (en) * 2002-02-21 2005-06-22 Eastern Virginia Med School PROTEIN BIOMARKERS DISTINGUISHING PROSTATIC CANCER OF NON-MALIGNANT CELLS
WO2003072738A2 (en) * 2002-02-22 2003-09-04 Board Of Trustees Of The University Of Illinois Beta chain-associated regulator of apoptosis
EP2388265A1 (en) 2002-02-22 2011-11-23 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US7662924B2 (en) * 2002-02-22 2010-02-16 The Board Of Trustees Of The University Of Illinois Beta chain-associated regulator of apoptosis
US7294471B2 (en) * 2002-02-27 2007-11-13 Cskeys, Llc Method for purifying cancer-specific proliferating cell nuclear antigen
US7494655B2 (en) 2002-03-05 2009-02-24 Ramot At Tel-Aviv University Ltd. Immunizing composition and method for inducing an immune response against the β-secretase cleavage site of amyloid precursor protein
AU2003221506A1 (en) 2002-03-19 2003-09-29 Novartis Ag Methods for the identification of compounds useful for the suppression of chronic neuropathic pain and compositions thereof
CA2479724A1 (en) * 2002-03-19 2003-10-02 Tularik Inc. Gene amplification in cancer
WO2003087763A2 (en) 2002-04-03 2003-10-23 Celltech R & D, Inc. Association of polymorphisms in the sost gene region with bone mineral density
AU2003241359A1 (en) * 2002-05-06 2003-11-11 Functional Genetics, Inc. Mammalian genes involed in rapamycin resistance and tumorgenesis: annexin xiii genes
AU2003299469A1 (en) * 2002-05-06 2004-05-25 Dana-Farber Cancer Institute, Inc. Use of a computer to design a molecule
US20040005615A1 (en) * 2002-05-24 2004-01-08 Jing Li Amplification and overexpression of oncogenes
EP2305710A3 (en) 2002-06-03 2013-05-29 Genentech, Inc. Synthetic antibody phage libraries
GB0213745D0 (en) 2002-06-14 2002-07-24 Univ Edinburgh Enzyme
JP2006517384A (ja) 2002-07-08 2006-07-27 ジェネンテック・インコーポレーテッド 免疫関連疾患の治療のための組成物と方法
US20040219609A1 (en) * 2002-07-12 2004-11-04 Day Anthony G. Methods for modulating proteins not previously known as proteases
AU2003251986A1 (en) * 2002-07-17 2004-02-02 U.S.Genomics, Inc. Methods and compositions for analyzing polymers using chimeric tags
ATE541047T1 (de) 2002-08-01 2012-01-15 Univ California Therapeutische monoklonale antikörper zur neutralisierung von botulinum neurotoxinen
AU2003254064A1 (en) * 2002-08-07 2004-02-25 Tularik Inc. Amplification and overexpression of oncogenes
AU2003259751C1 (en) 2002-08-13 2009-09-17 Qiagen Sciences, Llc Devices and methods for detecting amniotic fluid in vaginal secretions
WO2004020581A2 (en) * 2002-08-15 2004-03-11 Functional Genetics, Inc. Mammalian genes involved in rapamycin resistance and tumorgenesis: rapr7 genes
WO2004020582A2 (en) * 2002-08-15 2004-03-11 Functional Genetics, Inc. Mammalian genes involved in rapamycin resistance and tumorgenesis: rapr6 genes
US7906620B2 (en) 2002-08-16 2011-03-15 Yeda Research And Development Co. Ltd. Tumor associated antigen, peptides thereof, and use of same as anti-tumor vaccines
EP1953556B1 (en) 2002-08-23 2010-07-28 Bayer Schering Pharma Aktiengesellschaft Polypeptide biomarkers for diagnosing alzheimer's disease
US7785608B2 (en) * 2002-08-30 2010-08-31 Wyeth Holdings Corporation Immunogenic compositions for the prevention and treatment of meningococcal disease
WO2004022096A1 (en) 2002-09-06 2004-03-18 Alexion Pharmaceuticals, Inc. Method of treatment of asthma using antibodies to complement component c5
AU2003276874B2 (en) 2002-09-11 2009-09-03 Genentech, Inc. Novel compositions and methods for the treatment of immune related diseases
CA2497661A1 (en) 2002-09-11 2004-03-25 Genentech, Inc. Compositions and methods for the diagnosis of immune related diseases using pro71061
CA2498008C (en) 2002-09-11 2014-02-04 Genentech, Inc. Novel composition and methods for the treatment of immune related diseases
EP2444409A2 (en) 2002-09-16 2012-04-25 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US7094551B2 (en) * 2002-09-17 2006-08-22 Zahradnik Richard J Immunoassays, assay methods, antibodies and method of creating antibodies for detecting FGF-23
WO2004028479A2 (en) 2002-09-25 2004-04-08 Genentech, Inc. Nouvelles compositions et methodes de traitement du psoriasis
CA2498854A1 (en) * 2002-10-02 2004-04-15 Harald Kropshofer Novel mhc ii associated peptides
US7432351B1 (en) 2002-10-04 2008-10-07 Mayo Foundation For Medical Education And Research B7-H1 variants
EP1554584B1 (en) * 2002-10-11 2008-05-07 Sentina Biotechnology Incorporated Methods for detection of breast cancer
US20080293750A1 (en) * 2002-10-17 2008-11-27 Anna Helgadottir Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
JP3447009B1 (ja) * 2002-10-29 2003-09-16 實 平垣 構築物用構成体およびその製造方法
CA2503330A1 (en) 2002-10-29 2004-05-13 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
ES2463420T3 (es) * 2002-11-01 2014-05-27 Iris International, Inc. Inmuno-PCR sándwich por desplazamiento
EP2364716A3 (en) 2002-11-08 2012-01-11 Genentech, Inc. Compositions and methods for the treatment of natural killer cell related diseases
US20050129711A1 (en) * 2002-11-14 2005-06-16 Janakiraman Ramachandran Incapacitated whole-cell immunogenic bacterial compositions produced by recombinant expression
CA2506127C (en) 2002-11-15 2013-07-09 Morphotek, Inc. Methods of generating high-production of antibodies from hybridomas created by in vitro immunization
EP2314676A1 (en) 2002-11-26 2011-04-27 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US20040259226A1 (en) * 2003-05-30 2004-12-23 Robey W. Wade Monitoring for and detecting microbes used in bioterrorism
US20040101860A1 (en) * 2002-11-27 2004-05-27 Jones Alison M. Predicting animal performance
WO2004050873A1 (en) * 2002-11-29 2004-06-17 The University Of Hong Kong Genetically modified plants expressing proteinase inhibitors, sapina2a or sapin2b, and methods of use thereof for the inhibition of trypsin-and chymotrypsin-like activities
US20060275764A1 (en) * 2002-12-03 2006-12-07 Aarhus Universitet Method for determining predisposition to manifestation of immune system related diseases
JP2006518989A (ja) * 2002-12-31 2006-08-24 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー イヌのダイオキシン／アリール炭化水素受容体配列
AU2003288649A1 (en) * 2002-12-31 2004-07-22 Pharmacia & Upjohn Company Llc Canine cyp1a2 sequences
AU2003285724A1 (en) * 2002-12-31 2004-07-22 Pharmacia & Upjohn Company Llc Canine l-pbe sequences
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
WO2004065551A2 (en) * 2003-01-21 2004-08-05 Bristol-Myers Squibb Company Polynucleotide encoding a novel acyl coenzyme a, monoacylglycerol acyltransferase-3 (mgat3), and uses thereof
US7449321B2 (en) * 2003-01-22 2008-11-11 National University Of Singapore Molecules, compositions, methods and kits for applications associated with flaviviruses
DK2000481T3 (en) 2003-02-01 2016-06-06 Tanox Inc High affinity anti-human IgE antibodies
CA2514270A1 (en) * 2003-02-06 2004-08-19 Tripep Ab Antigen/antibody or ligand/receptor glycosylated specificity exchangers
US7335359B2 (en) 2003-02-06 2008-02-26 Tripep Ab Glycosylated specificity exchangers
US8021833B2 (en) * 2003-02-12 2011-09-20 Functional Genetics, Inc. Method for reducing HIV viral budding by administering a VPS28-specfic antibody that disrupts Gag-TSG101-VPS28 binding interactions
US7157551B2 (en) * 2003-02-14 2007-01-02 Cephalon, Inc. Compositions and methods for the detection and treatment of methylthioadenosine phosphorylase deficient cancers
GB0304515D0 (en) * 2003-02-27 2003-04-02 Dakocytomation Denmark As Standard
US20040178714A1 (en) * 2003-03-11 2004-09-16 Pan Wun Fang Decorative bulb of a series connected light string
US20040185446A1 (en) * 2003-03-18 2004-09-23 Jones Alison M. Cpn60 targets for quantification of microbial species
US20040185434A1 (en) * 2003-03-21 2004-09-23 Robey W. Wade Detecting microbial contamination in animal by-products
US20040185454A1 (en) * 2003-03-21 2004-09-23 Jones Alison M. Identification and quantification of microbial species in a sample
WO2004087758A2 (en) * 2003-03-26 2004-10-14 Neopharm, Inc. Il 13 receptor alpha 2 antibody and methods of use
DE602004022150D1 (de) * 2003-03-27 2009-09-03 Childrens Hosp Medical Center Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung
BRPI0409459A (pt) * 2003-04-16 2006-05-02 Wyeth Corp novas composições imunogênicas para a prevenção e tratamento de doença meningocócica
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
US7892745B2 (en) * 2003-04-24 2011-02-22 Xdx, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
KR100531760B1 (ko) * 2003-04-28 2005-11-29 대한민국(관리부서 : 농림부 국립수의과학검역원) 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트
US7892563B2 (en) * 2003-05-20 2011-02-22 Wyeth Holdings Corporation Methods for treatment of severe acute respiratory syndrome (SARS)
AU2004251161A1 (en) * 2003-05-30 2005-01-06 Genentech, Inc. Polypeptides that bind an anti-tissue factor antibody and uses thereof
US20040241662A1 (en) * 2003-05-30 2004-12-02 Robey W. Wade Detecting microbial contamination in grain and related products
US20050250094A1 (en) * 2003-05-30 2005-11-10 Nanosphere, Inc. Method for detecting analytes based on evanescent illumination and scatter-based detection of nanoparticle probe complexes
US7405274B2 (en) 2003-06-04 2008-07-29 Fibrogen, Inc. Connective tissue growth factor antibodies
AU2004247146A1 (en) * 2003-06-12 2004-12-23 Vaxgen, Inc. HIV-1 envelope glycoproteins having unusual disulfide structure
NZ544618A (en) * 2003-06-16 2009-02-28 Celltech R & D Inc Antibodies specific for sclerostin and methods for increasing bone mineralization
IL156495A0 (en) * 2003-06-17 2004-01-04 Prochon Biotech Ltd Use of fgfr3 antagonists for treating t cell mediated diseases
US8541003B2 (en) 2003-06-20 2013-09-24 Protein Sciences Corporation Vectors expressing SARS immunogens, compositions containing such vectors or expression products thereof, methods and assays for making and using
US20050026194A1 (en) * 2003-06-20 2005-02-03 Tularik Inc. Gene amplification and overexpression in cancer
HUE045709T2 (hu) 2003-07-08 2020-01-28 Genentech Inc Antagonista antitestek IL-17A/F heterológ polipeptidekhez
GB0315991D0 (en) * 2003-07-08 2003-08-13 Dakocytomation Denmark As Standard
US20050014734A1 (en) * 2003-07-18 2005-01-20 Genovate Biotechnology Co., Ltd. Modulation of interleukin-10 by DHEA
AU2004261941B2 (en) 2003-07-25 2008-04-10 Amgen Inc. Antagonists and agonists of LDCAM and methods of use
ES2391975T3 (es) * 2003-07-25 2012-12-03 Genvec, Inc. Vacunas a base de vector adenovírico
GB0317592D0 (en) * 2003-07-26 2003-08-27 Astrazeneca Ab Method
US20050106667A1 (en) 2003-08-01 2005-05-19 Genentech, Inc Binding polypeptides with restricted diversity sequences
JP5036310B2 (ja) 2003-08-06 2012-09-26 セノミックス インコーポレイテッド 新規な風味、風味改質剤、味覚剤、味覚向上剤、旨味および甘味味覚剤、および／またはそれらの向上剤および使用
WO2005019258A2 (en) 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
CA2536086C (en) 2003-08-20 2013-03-19 University Of Miami Inhibition of dr3 in the treatment of allergic lung inflammation
US7517495B2 (en) * 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
US20050048589A1 (en) * 2003-08-25 2005-03-03 Moncef Jendoubi Lung cancer specific gene products: their coding sequence, their antibodies and their use in diagnostic, therapeutic and disease management of lung cancer
JP4739207B2 (ja) 2003-08-29 2011-08-03 ダイアックス コーポレーション ポリペグ化されたプロテアーゼインヒビター
US7604994B2 (en) * 2003-09-03 2009-10-20 Morphotek, Inc. Genetically altered antibody-producing cell lines with improved antibody characteristics
CA2537984A1 (en) * 2003-09-05 2005-03-17 The Scripps Research Institute Detection of cholesterol ozonation products
CA2538664A1 (en) * 2003-09-19 2005-05-06 Decode Genetics Ehf. Inversion on chromosome 8p23 is a risk factor for anxiety disorders, depression and bipolar disorders
US20050214279A1 (en) * 2003-09-19 2005-09-29 Silverstein Samuel C Methods for stimulating human leukocytes to kill bacteria, yeast and fungi in biofilms that have formed in/on prosthetic devices, catheters, tissues and organs in vivo
US20050069958A1 (en) * 2003-09-26 2005-03-31 Mills Rhonda A. Method for simultaneous evaluation of a sample containing a cellular target and a soluble analyte
US20050069546A1 (en) 2003-09-30 2005-03-31 Yaron Ilan Educated NKT cells and their uses in the treatment of immune-related disorders
IL158287A0 (en) 2003-10-07 2004-05-12 Yeda Res & Dev Antibodies to nik, their preparation and use
ATE553218T1 (de) 2003-10-21 2012-04-15 Orion Genomics Llc Differentielle enzymatische fragmetierung
DE602004027291D1 (de) 2003-11-25 2010-07-01 Us Gov Health & Human Serv Mutierte anti-cd22-antikörper und immunkonjugate
CA2547351A1 (en) 2003-12-01 2005-07-07 Dade Behring Marburg Gmbh Homogeneous detection method
US20050118727A1 (en) * 2003-12-01 2005-06-02 Carsten Schelp Conjugates and their use in detection methods
SG10201404273QA (en) 2003-12-23 2014-10-30 Genentech Inc Novel anti-il 13 antibodies and uses thereof
EP2251695B1 (en) 2003-12-23 2013-07-17 Mount Sinai Hospital Corporation Markers associated with endometrial disease
US7150995B2 (en) * 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
EP2816351A3 (en) * 2004-01-27 2015-03-25 Compugen Ltd. Methods and systems for annotating biomolecular sequences
US8158362B2 (en) * 2005-03-30 2012-04-17 Decode Genetics Ehf. Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
US20100216863A1 (en) * 2004-01-30 2010-08-26 Decode Genetics Ehf. Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
WO2005079508A2 (en) * 2004-02-17 2005-09-01 Cancervax Corporation Method and composition for angiogenesis inhibition
EP2168986A3 (en) 2004-02-19 2010-07-28 Genentech, Inc. CDR-repaired antibodies
US7604956B2 (en) * 2004-03-01 2009-10-20 Biotraces, Inc. Supersensitive immunoassays
EP1731907B1 (en) * 2004-03-05 2010-10-13 Prima Meat Packers, Ltd. Method of detecting allergen
US20050227370A1 (en) * 2004-03-08 2005-10-13 Ramel Urs A Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays
PL2712617T3 (pl) 2004-03-12 2017-06-30 Intercept Pharmaceuticals, Inc. Leczenie zwłóknienia z zastosowaniem ligandów FXR
US20050221408A1 (en) * 2004-03-19 2005-10-06 U.S. Genomics, Inc. Compositions and methods for detection of single molecules
US7794713B2 (en) * 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
EP1745149A4 (en) 2004-04-15 2008-08-06 Univ Florida NEURALE PROTEINS AS BIOMARKERS FOR INJURY TO THE NERVOUS SYSTEM AND OTHER NEURAL DISORDERS
WO2005108989A2 (en) * 2004-04-16 2005-11-17 Genentech, Inc. Assay for antibodies
WO2005115394A2 (en) * 2004-04-20 2005-12-08 New York University School Of Medicine Prenyl-electrostatic switch, and methods of use
MXPA06012216A (es) 2004-04-23 2007-01-17 Pharmacia & Upjohn Co Llc Factor de tolerancia celular para virus y uso del mismo.
ES2389047T3 (es) 2004-04-29 2012-10-22 Otsuka Pharmaceutical Co., Ltd. Anticuerpos específicos contra la glicoproteína VI y procedimientos de producción de estos anticuerpos
EP1753449A4 (en) * 2004-04-30 2009-09-23 Corthera Inc METHOD AND COMPOSITIONS FOR CONTROLLING FEDERAL GROWTH BY RELAXIN MODULATION
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
US20050272101A1 (en) * 2004-06-07 2005-12-08 Prasad Devarajan Method for the early detection of renal injury
MY148646A (en) 2004-05-10 2013-05-15 Abgenomics Cooperatief Ua Anti-psgl-1 antibodies
UA105492C2 (uk) 2004-05-11 2014-05-26 Абдженомікс Коеператіеф У.А. Спосіб одержання антитіла для викликання смерті активованих т-клітин, спосіб визначення прийнятної сполуки для викликання смерті активованих т-клітин та фармацевтична композиція
AU2005246289A1 (en) * 2004-05-15 2005-12-01 Genentech, Inc. Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
US7504205B2 (en) * 2004-05-17 2009-03-17 The Burnham Institute Uncharacterized ORF3 in SARS-coronavirus is a cyclic-AMP-dependent kinase and a target for SARS therapy
US7604947B2 (en) * 2004-06-09 2009-10-20 Cornell Research Foundation, Inc. Detection and modulation of cancer stem cells
US20060040876A1 (en) 2004-06-10 2006-02-23 Rong-Hwa Lin Modulation of peroxisome proliferator-activated receptors
ES2660765T3 (es) 2004-06-21 2018-03-26 The Board Of Trustees Of The Leland Stanford Junior University Genes y rutas expresadas de forma diferencial en trastorno bipolar y/o trastorno depresivo mayor
US8034553B2 (en) 2004-06-24 2011-10-11 Kimberly-Clark Worldwide, Inc. Biomarkers for wound healing
US7973134B2 (en) * 2004-07-07 2011-07-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
WO2006012451A2 (en) 2004-07-22 2006-02-02 Five Prime Therapeutics, Inc. Compositions and methods of use for mgd-csf in disease treatment
US7342093B2 (en) 2004-07-23 2008-03-11 University Of Massachusetts Compounds that inhibit Hsp90 protein-protein interactions with IAP proteins
US20060024744A1 (en) * 2004-07-28 2006-02-02 Mills Rhonda A Methods for substantially simultaneous evaluation of a sample containing a cellular target and a soluble analyte
EP1784510A4 (en) * 2004-08-02 2010-08-04 Janssen Pharmaceutica Nv IRAK1C SPLICE VARIANT AND USE THEREOF
WO2006023312A2 (en) * 2004-08-20 2006-03-02 Carl Deirmengian Diagnostic assay for source of inflammation
US7893197B2 (en) * 2004-08-25 2011-02-22 Janssen Pharmaceutica N.V. Relaxin-3 chimeric polypeptides and their preparation and use
JP2008511336A (ja) * 2004-09-01 2008-04-17 アメリカ合衆国 免疫原性が増加したアデノウイルスベクターをインビボで用いる方法
US7645575B2 (en) * 2004-09-08 2010-01-12 Xdx, Inc. Genes useful for diagnosing and monitoring inflammation related disorders
FI20041204A0 (fi) 2004-09-16 2004-09-16 Riikka Lund Menetelmät immuunivälitteisiin sairauksiin liittyvien uusien kohdegeenien hyödyntämiseksi
GB0421639D0 (en) 2004-09-29 2004-10-27 Proteome Sciences Plc Methods and compositions relating to alzheimer's disease
US7935790B2 (en) * 2004-10-04 2011-05-03 Cell Singaling Technology, Inc. Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
WO2006042002A2 (en) * 2004-10-05 2006-04-20 Oregon Health And Science University Compositions and methods for treating disease
SI3428191T1 (sl) 2004-10-06 2025-03-31 Mayo Foundation For Medical Education And Research B7-H1 in PD-1 v zdravljenju karcinoma ledvičnih celic
US8969291B2 (en) 2004-10-08 2015-03-03 Enzo Therapeutics, Inc. Methods for decreasing leptin levels or activity for treating inflammation
WO2006047417A2 (en) 2004-10-21 2006-05-04 University Of Florida Research Foundation, Inc. Detection of cannabinoid receptor biomarkers and uses thereof
HUE026826T2 (en) 2004-10-29 2016-07-28 Ratiopharm Gmbh Modeling and glycopegylation of fibroblast growth factor (FGF)
PT1815028E (pt) 2004-11-03 2012-01-24 Iris Molecular Diagnostics Inc Microbolhas para separação por afinidade
KR20070105967A (ko) * 2004-11-03 2007-10-31 아이리스 몰레큘라 다이아그노스틱스, 인코오포레이티드 균질 분석물 탐지
AU2005302083A1 (en) * 2004-11-04 2006-05-11 Fibron Limited Treatment of B-cell malignancies
JP5341350B2 (ja) 2004-11-16 2013-11-13 トラスティーズ オブ ボストン ユニバーシティ 高血圧および血管新生におけるエンドセリン−１／アンジオテンシンｉｉ二重レセプター（ｄｅａｒ）の役割
EP1659407A1 (en) * 2004-11-19 2006-05-24 Norwegian Antibodies AS Diagnostic control system
US7704955B2 (en) 2004-11-24 2010-04-27 Neopro Pain, Inc. Methods and compositions for modulating conditions in both mammals and plants
US7608277B2 (en) 2004-12-01 2009-10-27 Gene Therapy Systems, Inc. Tuberculosis nucleic acids, polypeptides and immunogenic compositions
EP3489689B1 (en) * 2004-12-20 2020-06-17 Antibodyshop A/S Determination of neutrophil gelatinase-associated lipocalin (ngal) as a diagnostic marker for renal disorders
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
JP2008525041A (ja) 2004-12-22 2008-07-17 ジェネンテック・インコーポレーテッド 可溶性多膜貫通型タンパク質の産生方法
CA2531616A1 (en) * 2004-12-28 2006-06-28 Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd.) High strength thin steel sheet having high hydrogen embrittlement resisting property and high workability
US8697674B2 (en) 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
EP1831366A2 (en) 2004-12-30 2007-09-12 Agency for Science, Technology and Research Chinese hamster apoptosis-related genes
JP2008528060A (ja) 2005-01-27 2008-07-31 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ボツリヌス神経毒素を中和する治療的モノクローナル抗体
WO2006089125A2 (en) * 2005-02-16 2006-08-24 Dana-Farber Cancer Institute Methods of detecting ovarian cancer
WO2006095348A2 (en) * 2005-03-10 2006-09-14 Hadasit Medical Research Services & Development Ltd. Antigen specific lymphocytes, compositions thereof, and methods for isolation and preparation thereof
EP2481424A1 (en) 2005-03-19 2012-08-01 Medical Research Council Improvements in or relating to treatment and prevention of hepatitis C viral infections
WO2006102497A2 (en) * 2005-03-22 2006-09-28 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for diagnosis, monitoring and development of therapeutics for treatment of atherosclerotic disease
DK2567976T3 (en) 2005-03-23 2017-10-23 Genmab As ANTIBODIES AGAINST CD38 FOR TREATMENT OF MULTIPLE MYLOMA
US8323645B2 (en) 2005-03-24 2012-12-04 Millennium Pharmaceuticals, Inc. Antibodies that bind OV064 and methods of use therefor
US20070037232A1 (en) * 2005-03-31 2007-02-15 Barasch Jonathan M Detection of NGAL in chronic renal disease
WO2006107846A2 (en) 2005-04-01 2006-10-12 University Of Florida Research Foundation, Inc. Biomakers of liver injury
US8048638B2 (en) * 2005-04-01 2011-11-01 University Of Florida Research Foundation, Inc. Biomarkers of liver injury
US8124350B2 (en) 2005-04-04 2012-02-28 Biogen Idec Ma Inc. Methods and products for evaluating an immune response to a therapeutic protein
US9187546B2 (en) 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
EP3321359B1 (en) 2005-04-11 2020-12-02 Horizon Pharma Rheumatology LLC Variant forms of urate oxidase and use thereof
US20090099340A1 (en) * 2007-10-12 2009-04-16 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
JP2008541051A (ja) * 2005-05-02 2008-11-20 ザ・キュレーターズ・オブ・ザ・ユニバーシティ・オブ・ミズーリ 炭水化物バイオマーカーの検出
US7592429B2 (en) 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
US8003108B2 (en) 2005-05-03 2011-08-23 Amgen Inc. Sclerostin epitopes
WO2006122295A2 (en) * 2005-05-11 2006-11-16 Expression Diagnostics, Inc. Methods of monitoring functional status of transplants using gene panels
WO2006125021A2 (en) * 2005-05-16 2006-11-23 Dana Farber Cancer Institute, Inc. Fibrinogen alpha and hemoglobin polypeptides as cancer markers
NZ563913A (en) 2005-05-18 2010-03-26 Decode Genetics Ehf Markers for prostate cancer in LD Block A on chromosome 8q24.21
CA2608162C (en) * 2005-05-23 2013-11-12 Phadia Ab Two step lateral flow assay methods and devices
US7968697B2 (en) * 2005-05-25 2011-06-28 Chrontech Pharma Ab Hepatitis C virus non-structural NS3/4A fusion gene
ES2397355T5 (es) 2005-06-08 2020-11-10 Dana Farber Cancer Inst Inc Métodos y composiciones para el tratamiento de infecciones persistentes y cáncer por inhibición de la vía de muerte celular programada (PD-1)
AU2006260477B2 (en) * 2005-06-20 2012-02-23 Decode Genetics Ehf. Genetic variants in the TCF7L2 gene as diagnostic markers for risk of type 2 diabetes mellitus
WO2007008604A2 (en) * 2005-07-08 2007-01-18 Bristol-Myers Squibb Company Single nucleotide polymorphisms associated with dose-dependent edema and methods of use thereof
US7906297B2 (en) 2005-07-20 2011-03-15 Cell Signaling Technology, Inc. Reagents for the detection of phosphorylated ATR kinase (Ser 428) and uses thereof
AU2006278260B2 (en) * 2005-08-08 2012-03-08 Onconon, Llc. Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility
US20070202512A1 (en) * 2005-08-19 2007-08-30 Bristol-Myers Squibb Company Human single nucleotide polymorphisms associated with dose-dependent weight gain and methods of use thereof
WO2007027751A2 (en) 2005-08-30 2007-03-08 University Of Miami Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins
EP2182057A1 (en) 2005-08-31 2010-05-05 Cell Signaling Technology, Inc. Antibody agains phosphorylated Tyrosine for the detection of protein phosphorylation in carcinoma signaling pathways
US20100151495A9 (en) * 2005-08-31 2010-06-17 Cell Signaling Technolgy, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
EP1934867A2 (en) * 2005-08-31 2008-06-25 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
US8193328B2 (en) * 2005-09-08 2012-06-05 Philadelphia Health & Education Corporation Identification of modulators of serine protease inhibitor Kazal and their use as anti-cancer and anti-viral agents
WO2007029054A1 (en) * 2005-09-09 2007-03-15 Glycofi, Inc. Immunoglobulin comprising predominantly a man7glcnac2, man8glcnac2 glycoform
US7611834B2 (en) * 2005-09-30 2009-11-03 Sandia Corporation Methods and devices for protein assays
IL172297A (en) 2005-10-03 2016-03-31 Compugen Ltd Soluble vegfr-1 variants for the diagnosis of preeclampsia
US8119358B2 (en) 2005-10-11 2012-02-21 Tethys Bioscience, Inc. Diabetes-related biomarkers and methods of use thereof
AU2006302031A1 (en) 2005-10-11 2007-04-19 Tethys Bioscience, Inc. Diabetes-associated markers and methods of use thereof
US20080090304A1 (en) * 2006-10-13 2008-04-17 Barasch Jonathan Matthew Diagnosis and monitoring of chronic renal disease using ngal
US20090155850A1 (en) * 2005-10-28 2009-06-18 The Florida International University Board Of Trustees Horse:Human Chimeric Antibodies
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US8399201B2 (en) * 2005-10-31 2013-03-19 Janssen Pharmaceutica N.V. Polypeptide complex of TRPM8 and calmodulin and its uses thereof
CN101346393B (zh) 2005-11-02 2015-07-22 普洛体维生物治疗公司 修饰的siRNA分子及其应用
EP2998318A1 (en) 2005-11-04 2016-03-23 Genentech, Inc. Use of complement pathway inhibitors to treat ocular diseases
ZA200804082B (en) 2005-11-07 2010-02-24 Scripps Research Inst Compositions and methods for controlling tissue factor signaling specificity
US20070161089A1 (en) * 2005-11-08 2007-07-12 Genentech, Inc. Method of Producing Pan-Specific Antibodies
UA96139C2 (uk) 2005-11-08 2011-10-10 Дженентек, Інк. Антитіло до нейропіліну-1 (nrp1)
DK2564864T3 (en) 2005-11-12 2015-04-07 Trustees Of The Leland Board Of FGF-2 related methods for the diagnosis and treatment of depression
EP2299267A3 (en) 2005-11-16 2011-05-04 Novartis AG Biomarkers for anti-NogoA antibody treatment in spinal cord injury
MY147669A (en) 2005-11-18 2012-12-31 Glenmark Pharmaceuticals Sa Anti-alpha2 integrin antibodies and their uses
AU2006340750B2 (en) 2005-11-28 2013-03-07 Zymogenetics, Inc. IL-21 antagonists
CN103710430B (zh) 2005-11-29 2016-03-30 剑桥企业有限公司 乳腺癌标志物
US7822474B2 (en) * 2005-11-30 2010-10-26 Cedars-Sinai Medical Center Methods for the prediction of arrhythmias and prevention of sudden cardiac death
CN105859886A (zh) 2005-12-02 2016-08-17 健泰科生物技术公司 牵涉与il-22和il-22r结合的抗体的组合物和方法
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
CA2634797A1 (en) 2005-12-22 2007-07-05 Abbott Laboratories Methods and marker combinations for screening for predisposition to lung cancer
US9347945B2 (en) 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
US20100015642A1 (en) * 2006-01-05 2010-01-21 Kwon Eugene D B7-h1 and survivin in cancer
US20090215084A1 (en) * 2006-01-05 2009-08-27 Mayo Foundation For Medical Education And Research B7-h1 and b7-h4 in cancer
JP5404052B2 (ja) 2006-01-12 2014-01-29 アレクシオン ファーマシューティカルズ， インコーポレイテッド Ｏｘ−２／ｃｄ２００への抗体およびその使用
WO2007084397A2 (en) * 2006-01-12 2007-07-26 Janssen Pharmaceutica N.V. Processing of slpi by chymase
WO2007080597A2 (en) 2006-01-16 2007-07-19 Compugen Ltd. Polynucleotide and polypeptide sequences and methods for diagnosis
EP3360965A1 (en) 2006-01-20 2018-08-15 Cell Signaling Technology, Inc. Translocation and mutant ros kinase in human non-small cell lung carcinoma
US20120208824A1 (en) 2006-01-20 2012-08-16 Cell Signaling Technology, Inc. ROS Kinase in Lung Cancer
WO2007100580A2 (en) * 2006-02-22 2007-09-07 The Texas A & M University System Antibodies recognizing a highly expressed putative antigen of ca-mrsa and methods of use
US7994126B2 (en) 2006-02-22 2011-08-09 Zhenglun Zhu Treatment of cellular proliferative disorders with compositions comprising Hom polypeptide (also known as Xom, VENTX2)
LT2676967T (lt) 2006-02-28 2019-09-10 Biogen Ma Inc. Uždegiminių ir autoimuninių ligų gydymo būdai su natalizumabu
EP1991267B1 (en) 2006-03-03 2017-12-20 Biogen MA Inc. Methods of treating inflammatory and autoimmune diseases with natalizumab
AU2007227218A1 (en) 2006-03-22 2007-09-27 Viral Logic Systems Technology Corp. Methods for identifying polypeptide targets and uses thereof for treating immunological diseases
US8129334B2 (en) 2006-03-31 2012-03-06 The Regents Of The University Of California Methods and compositions for treating neurodegenerative disorders and Alzheimer'S disease and improving normal memory
CN101578297A (zh) * 2006-04-07 2009-11-11 美国政府健康及人类服务部 治疗肿瘤疾病的抗体组合物和方法
AU2007309726A1 (en) * 2006-04-07 2008-05-02 Xdx, Inc. Steroid responsive nucleic acid expression and prediction of disease activity
JP5033177B2 (ja) * 2006-04-12 2012-09-26 サビエント ファーマセウティカルズ インク． 陽イオン界面活性剤によるタンパク質の精製
SI2450437T1 (sl) 2006-04-14 2017-12-29 Cell Signaling Technology Inc. Okvarjenost genov in mutantna ALK kinaza v človeških solidnih tumorjih
WO2007124361A2 (en) * 2006-04-20 2007-11-01 Mayo Foundation For Medical Education And Research Soluble b7-h1
DK3235811T3 (en) 2006-04-21 2018-11-12 Senomyx Inc PROCEDURE FOR THE PREPARATION OF OXALAMIDS
US20090298093A1 (en) * 2006-04-27 2009-12-03 Roberto Polakiewicz Reagents for the Detection of Protein Phosphorylation in ATM & ATR Kinase Signaling Pathways
BRPI0710407A2 (pt) 2006-05-04 2012-04-17 Genentech Inc poliptìdeos, peixes-zebra transgênicos, modelos de sistemas, métodos de identificação de compostos, de identificação de agentes, métodos de tratamento de disfunções relativas a apoptose, método de identificação de agentes de prevenção ou redução da apoptose, composição de aumento da apoptose, composições de redução ou prevenção de apoptose, composição de apoptose, método de detecção, kits e artigo industrializado
EP2021495A4 (en) * 2006-05-09 2009-06-24 Musc Found For Res Dev Detecting diastolic heart failure by protease and protease inhibitor plasma profiling
US20080131431A1 (en) * 2006-05-15 2008-06-05 Viral Logic Systems Technology Corp. CD47 related compositions and methods for treating immunological diseases and disorders
US8377448B2 (en) * 2006-05-15 2013-02-19 The Board Of Trustees Of The Leland Standford Junior University CD47 related compositions and methods for treating immunological diseases and disorders
US7745584B2 (en) * 2006-05-22 2010-06-29 California Institute Of Technology Antibodies to sulfated carbohydrates
US20100196336A1 (en) 2006-05-23 2010-08-05 Dongsu Park Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
EP1862538A1 (en) * 2006-05-29 2007-12-05 IMBA-Institut für Molekulare Biotechnologie GmbH siRNA kinase and methods of use
US20090197280A1 (en) 2006-05-30 2009-08-06 Kristian Bangert Methods and Devices for Rapid Assessment of Severity of Injury
US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
CA2659082A1 (en) 2006-06-07 2007-12-21 Tethys Bioscience, Inc. Markers associated with arteriovascular events and methods of use thereof
EP2046384A4 (en) * 2006-06-15 2009-12-02 Fibron Ltd ANTIBODIES BLOCKING FIBROBLAST GROWTH FACTOR RECEPTOR ACTIVATION AND METHODS OF USING THE SAME
WO2007150069A2 (en) 2006-06-23 2007-12-27 Myriad Genetics, Inc. Dpyd gene variants and use thereof
AU2007264672B2 (en) 2006-06-28 2013-03-14 Hadasit Medical Research Services & Development Ltd Caspase-8 and inflammation, infection and wound healing
US20080004410A1 (en) * 2006-06-30 2008-01-03 Yu-Chin Lai Hydrophilic macromonomers having alpha,beta-conjugated carboxylic terminal group and medical devices incorporating same
US7572618B2 (en) 2006-06-30 2009-08-11 Bristol-Myers Squibb Company Polynucleotides encoding novel PCSK9 variants
KR20090046825A (ko) * 2006-07-11 2009-05-11 무스크 파운데이션 포 리서치 디벨롭먼트 프로테아제 및 프로테아제 저해제 프로파일링으로 심근 경색 후 심부전을 예측하는 방법
MY150687A (en) 2006-07-21 2014-02-28 Femalon S P R L Assay and kit for predicting implantation success in assisted fertilisation
ATE465179T1 (de) 2006-07-24 2010-05-15 Pasteur Institut Antikörper, antikörperfragmente und scfv die an posttranslational modifizierte neurotrophine binden
EP2064553B2 (en) * 2006-08-07 2023-06-07 Antibodyshop A/S Diagnostic test to exclude significant renal injury
WO2008021954A2 (en) * 2006-08-09 2008-02-21 Biogen Idec Ma Inc. Method for distribution of a drug
US7939636B2 (en) * 2006-08-11 2011-05-10 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in c-Src signaling pathways
WO2008021431A2 (en) * 2006-08-14 2008-02-21 Xdx, Inc. Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders
US20090258442A1 (en) * 2006-08-31 2009-10-15 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US7951776B2 (en) 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US20090203602A1 (en) * 2006-09-01 2009-08-13 Cohava Gelber Compositions and methods for diagnosis and treatment of type 2 diabetes
US20080300170A1 (en) * 2006-09-01 2008-12-04 Cohava Gelber Compositions and methods for diagnosis and treatment for type 2 diabetes
US20100267052A1 (en) * 2006-09-01 2010-10-21 American Type Culture Collection Compositions and methods for diagnosis and treatment of type 2 diabetes
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
JP5926475B2 (ja) 2006-09-21 2016-05-25 ユニバーシティー オブ ロチェスター 筋緊張性ジストロフィーのためのタンパク質置換治療に関する組成物および方法
EP3753576A1 (en) 2006-09-26 2020-12-23 Genmab A/S Combination treatment of cd38-expressing tumors
HRP20140675T1 (hr) 2006-10-04 2014-10-10 Genentech, Inc. Elisa za vegf
WO2008066626A2 (en) * 2006-10-25 2008-06-05 The Rockefeller University METHODS FOR THE TREATMENT OF Aβ RELATED DISORDERS AND COMPOSITIONS THEREFOR
US8329399B2 (en) 2006-10-27 2012-12-11 Siu K W Michael Endometrial biomarkers
KR101581279B1 (ko) 2006-10-27 2015-12-31 엘파스, 인크. 스핑고신-1-포스페이트 결합을 위한 조성물 및 방법
AU2007313822A1 (en) 2006-10-27 2008-05-08 Lpath, Inc. Compositions and methods for treating ocular diseases and conditions
US20080125368A1 (en) * 2006-10-31 2008-05-29 Imperial Innovations Limited Methods
US20100104572A1 (en) * 2006-11-02 2010-04-29 Sylvie Luria Methods for screening for therapeutic molecules and use of the molecules therefrom
KR101645144B1 (ko) 2006-11-02 2016-08-03 제넨테크, 인크. 인간화 항-ｄ 인자 항체
WO2008140484A2 (en) * 2006-11-09 2008-11-20 Xdx, Inc. Methods for diagnosing and monitoring the status of systemic lupus erythematosus
WO2008061013A2 (en) * 2006-11-10 2008-05-22 Amgen Inc. Antibody-based diagnostics and therapeutics
WO2008133722A2 (en) * 2006-11-10 2008-11-06 Ucb Pharma S.A. Anti human sclerostin antibodies
US20080112847A1 (en) * 2006-11-15 2008-05-15 Nancy Yu Chen Collecting and testing device and method of use
WO2008064040A2 (en) * 2006-11-22 2008-05-29 The Board Of Regents Of The University Of Texas System Methods and compositions using chelator-antibody conjugates
CA2683909A1 (en) * 2006-11-30 2008-06-05 Decode Genetics Ehf. Genetic susceptibility variants of type 2 diabetes mellitus
EP2094850B1 (en) 2006-12-01 2013-06-12 Agency for Science, Technology And Research Cancer-related protein kinases
CA2673123C (en) * 2006-12-05 2019-04-30 Decode Genetics Ehf. Genetic markers for risk management of cardiac arrhythmia
BRPI0719409A2 (pt) 2006-12-18 2014-02-11 Genentch Inc "regiões variáveis da cadeia pesada ("vh"), sequências da cadeia vh, ácido nucléico, vetor, célula, anticorpos, uso do anticorpo, método para produzir um anticorpo, anticorpo anti-notch3 e forma humanizada do anticorpo"
US20090186034A1 (en) * 2006-12-19 2009-07-23 Genetech, Inc. Gene expression markers for inflammatory bowel disease
WO2008079322A1 (en) * 2006-12-22 2008-07-03 Beckman Coulter, Inc. Methods, kits and materials for diagnosing disease states by measuring isoforms or proforms of myeloperoxidase
US20100129358A1 (en) 2006-12-22 2010-05-27 University Of Utah Research Foundation Method of detecting ocular diseases and pathologic conditions and treatment of same
AR064642A1 (es) * 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
US20090142342A1 (en) * 2006-12-27 2009-06-04 Johns Hopkins University B7-h4 receptor agonist compositions and methods for treating inflammation and auto-immune diseases
AU2007339762B2 (en) * 2006-12-27 2011-03-31 The Johns Hopkins University Compositions and methods for treating inflammation and auto-immune diseases
US7989173B2 (en) 2006-12-27 2011-08-02 The Johns Hopkins University Detection and diagnosis of inflammatory disorders
US8930178B2 (en) 2007-01-04 2015-01-06 Children's Hospital Medical Center Processing text with domain-specific spreading activation methods
WO2008085895A2 (en) * 2007-01-04 2008-07-17 Musc Foundation For Research Development Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling
WO2008097461A2 (en) * 2007-02-02 2008-08-14 Amgen Inc Hepcidin and hepcidin antibodies
JP2010520745A (ja) 2007-02-07 2010-06-17 デコード・ジェネティクス・イーエイチエフ 前立腺癌のリスクに寄与する遺伝子変異体
CN101668865B (zh) * 2007-02-21 2015-05-06 解码遗传学私营有限责任公司 与心血管疾病相关联的遗传易感性变体
US20090081659A1 (en) 2007-03-07 2009-03-26 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
WO2008113363A1 (en) * 2007-03-21 2008-09-25 Bioporto Diagnostics A/S Diagnostic test for renal injury
US7960139B2 (en) 2007-03-23 2011-06-14 Academia Sinica Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
US20090092631A1 (en) * 2007-03-26 2009-04-09 Tripep Ab Glycosylated specificity exchangers that induce an antibody dependent cellular cytotoxicity (adcc) response
EP1975184A3 (en) 2007-03-26 2008-11-26 Cell Signaling Technology, Inc. Serine or threonine phosphorylation sites
WO2008118324A2 (en) 2007-03-26 2008-10-02 Macrogenics, Inc. Composition and method of treating cancer with an anti-uroplakin ib antibody
WO2008117314A2 (en) * 2007-03-26 2008-10-02 Decode Genetics Ehf Genetic variants on chr2 and chr16 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment
AU2008231575A1 (en) 2007-03-27 2008-10-02 Immunovia Ab Protein signature/markers for the detection of adenocarcinoma
US20080238709A1 (en) * 2007-03-28 2008-10-02 Faramarz Vaziri One-way communication apparatus with dynamic key generation
EP2144935A2 (en) 2007-03-29 2010-01-20 Technion Research & Development Foundation Ltd. Antibodies, methods and kits for diagnosing and treating melanoma
US20100291562A1 (en) * 2007-04-04 2010-11-18 Michael Adler Method for the detection of an analyte in biological matrix
US20090182035A1 (en) * 2007-04-11 2009-07-16 Alcon Research, Ltd. Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
CA2682730A1 (en) * 2007-04-11 2008-10-23 Alcon Research, Ltd. Use of an inhibitor of tnf.alpha. plus an antihistamine to treat allergic rhinitis and allergic conjunctivitis
EP2891885A3 (en) 2007-04-18 2015-10-14 Health Diagnostic Laboratory, Inc. Diabetes-related biomarkers and methods of use thereof
US7977462B2 (en) 2007-04-19 2011-07-12 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
EP1983003A3 (en) 2007-04-19 2009-03-11 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
EP1983002A3 (en) 2007-04-19 2009-03-11 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
WO2008132516A1 (en) 2007-04-26 2008-11-06 Opsona Therapeutics Limited Toll-like receptor binding epitope and compositions for binding thereto
US20090004677A1 (en) * 2007-04-27 2009-01-01 The Board Of Trustees Of The University Of Illinois Quantitative determination of bcl10
US20090053831A1 (en) 2007-05-01 2009-02-26 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
RU2504586C2 (ru) 2007-05-01 2014-01-20 Хилл'С Пет Ньютришн, Инк. Способы и композиции для диагностики остеоартрита у животного семейства кошачьих
GB0709092D0 (en) * 2007-05-11 2007-06-20 Borrebaeck Carl Diagnosis and method of disease
US20100256464A1 (en) * 2007-05-14 2010-10-07 Dr. Susan Love Research Foundation Device for determining risk of developing breast cancer and method thereof
AU2008256219B2 (en) 2007-05-25 2014-06-05 Decode Genetics Ehf. Genetic variants on Chr 5p12 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment
WO2008150841A1 (en) 2007-05-30 2008-12-11 Lpath, Inc. Compositions and methods for binding lysophosphatidic acid
US9163091B2 (en) * 2007-05-30 2015-10-20 Lpath, Inc. Compositions and methods for binding lysophosphatidic acid
EP2544006A1 (en) 2007-06-04 2013-01-09 Diagnoplex Biomarker combinations for colorectal cancer
US9273134B2 (en) 2007-06-05 2016-03-01 Yale University Inhibitors of receptor tyrosine kinases and methods of use thereof
CA2917355C (en) 2007-06-08 2018-07-17 Genentech, Inc. Gene expression markers of tumor resistance to her2 inhibitor treatment
WO2009009127A2 (en) * 2007-07-12 2009-01-15 U.S. Genomics, Inc. Method and system for transferring and/or concentrating a sample
EP2170946A2 (en) 2007-07-13 2010-04-07 The Johns Hopkins University B7-dc variants
WO2009014744A1 (en) * 2007-07-25 2009-01-29 Alexion Pharmaceutical, Inc. Methods and compositions for treating autoimmune disease
WO2009019260A2 (en) 2007-08-03 2009-02-12 Opsona Therapeutics Limited Composition and method for treatment of reperfusion injury and tissue damage
US8071561B2 (en) * 2007-08-16 2011-12-06 Chrontech Pharma Ab Immunogen platform
CN101842115B (zh) 2007-08-29 2014-07-30 塞诺菲-安万特股份有限公司 人源化的抗-cxcr5抗体、其衍生物及它们的应用
HUE042982T2 (hu) 2007-09-04 2019-07-29 Compugen Ltd Polipeptidek és polinukleotidok, és alkalmazásuk drogcélpontként drogok és biológiai szerek elõállítására
US20090111131A1 (en) * 2007-09-13 2009-04-30 Seth Fishman Method of detecting protein losing enteropathy in animals
CL2008002775A1 (es) 2007-09-17 2008-11-07 Amgen Inc Uso de un agente de unión a esclerostina para inhibir la resorción ósea.
WO2009048530A2 (en) 2007-10-05 2009-04-16 Panomics, Inc. Highly multiplexed particle-based assays
AU2008310530A1 (en) * 2007-10-12 2009-04-16 Decode Genetics Ehf Sequence variants for inferring human pigmentation patterns
EP2050764A1 (en) 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
DK2203558T3 (en) 2007-10-18 2016-06-27 Cell Signaling Technology Inc TRANSLOCATION AND mutant ROS kinase IN HUMAN NON-small cell lung carcinoma
EP2573113A3 (en) 2007-10-23 2013-07-24 The Cleveland Clinic Foundation Oxidant resistant apolipoprotein a-1 and mimetic peptides
US8361465B2 (en) * 2007-10-26 2013-01-29 Lpath, Inc. Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
WO2009062102A2 (en) 2007-11-07 2009-05-14 Genentech, Inc. Compositions and methods for treatment of microbial disorders
JP5710978B2 (ja) 2007-11-08 2015-04-30 ネオジェニックス オンコロジー， インコーポレイテッド 結腸癌および膵臓癌に対する組み換えモノクローナル抗体および対応抗原
CN101910845A (zh) * 2007-11-15 2010-12-08 比奥波托诊断股份公司 个体分子形式的生物标志的诊断用途
EP2728017B1 (en) 2007-11-19 2016-08-24 Celera Corporation Lung cancer markers and uses thereof
US20090203043A1 (en) 2007-11-21 2009-08-13 Peter Hornbeck Protein phosphorylation by basophilic serine/threonine kinases in insulin signaling pathways
US8912149B1 (en) 2007-11-28 2014-12-16 California Institute Of Technology Glycosaminoglycan mimetics
JP2011509071A (ja) 2007-11-29 2011-03-24 ジェネンテック， インコーポレイテッド 炎症性腸疾患のための遺伝子発現マーカー
US8697360B2 (en) 2007-11-30 2014-04-15 Decode Genetics Ehf. Genetic variants on CHR 11Q and 6Q as markers for prostate and colorectal cancer predisposition
EP2217268B1 (en) 2007-12-07 2016-05-04 ZymoGenetics, Inc. Anti-human il-21 monoclonal antibodies
CN101952442A (zh) 2007-12-13 2011-01-19 菲利普莫里斯生产公司 就减少的镉转运进行修饰的转基因植物、衍生产物和相关方法
MX2010006519A (es) * 2007-12-14 2010-10-15 Amgen Inc Metodo para tratar una fractura de hueso con anticuerpos anti-esclerostina.
AU2008342535B2 (en) 2007-12-27 2015-02-05 Arbutus Biopharma Corporation Silencing of polo-like kinase expression using interfering RNA
DE202008000834U1 (de) 2008-01-21 2008-05-29 Chin, Li-Te Zusammensetzung und Reagenz für CTLA-4 und Verwendungen derselben
EP2803675A3 (en) 2008-01-25 2014-12-24 Amgen, Inc Ferroportin antibodies and methods of use
AU2009208607B2 (en) * 2008-01-31 2013-08-01 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
CA2618163A1 (en) 2008-02-07 2009-08-07 K. W. Michael Siu Head and neck cancer biomarkers
WO2009101639A1 (en) 2008-02-14 2009-08-20 Decode Genetics Ehf. Susceptibility variants for lung cancer
EP2252893B1 (en) * 2008-02-21 2013-10-23 Iris International, Inc. Method for early determination of recurrence after therapy for prostate cancer
WO2009111315A2 (en) * 2008-02-29 2009-09-11 Mayo Foundation For Medical Education And Research Methods for reducing granulomatous inflammation
US20090220991A1 (en) * 2008-02-29 2009-09-03 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
WO2009151693A2 (en) 2008-03-14 2009-12-17 Eastern Virginia Medical School Imaging mass spectrometry for improved prostate cancer diagnostics
US8993231B2 (en) * 2008-03-18 2015-03-31 Marshall University Research Corporation Methods for stem cell production and therapy
US8808985B2 (en) 2008-04-01 2014-08-19 Decode Genetics Ehf. Susceptibility variants for peripheral arterial disease and abdominal aortic aneurysm
MX2010010737A (es) 2008-04-02 2010-12-20 Macrogenics Inc Anticuerpos especificos para her2/neu y metodos para utilizar los mismos.
ES2654937T3 (es) 2008-04-02 2018-02-15 Macrogenics, Inc. Anticuerpos específicos para el complejo BCR y procedimientos de uso de los mismos
KR101855381B1 (ko) 2008-04-09 2018-05-09 제넨테크, 인크. 면역 관련 질병의 치료를 위한 신규한 조성물 및 방법
US10000568B2 (en) 2008-04-10 2018-06-19 Cell Signaling Technology, Inc. Compositions and methods for detecting EGFR in cancer
EP2770057A1 (en) 2008-04-15 2014-08-27 Protiva Biotherapeutics Inc. Silencing of CSN5 gene expression using interfering RNA
PL2279254T3 (pl) 2008-04-15 2017-11-30 Protiva Biotherapeutics Inc. Nowe preparaty lipidowe do dostarczania kwasów nukleinowych
WO2009130588A2 (en) * 2008-04-22 2009-10-29 Tripep Ab Immunogen platform
TWI453031B (zh) 2008-04-25 2014-09-21 Dyax Corp Ｆｃ受體結合蛋白
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
AU2009246946B2 (en) 2008-05-01 2013-09-26 Amgen Inc. Anti-hepcidin antibodies and methods of use
EP2116261A1 (en) 2008-05-07 2009-11-11 Institut Pasteur Sub-region of a plasmodium protein with improved vaccine potential and medical uses thereof
EP2304047A4 (en) 2008-05-07 2012-12-26 Eutropics Pharmaceuticals Inc ANTIBODIES TAKEN UPON HETERODIMES OF THE BCL-2 FAMILY AND THEIR USES
SG157299A1 (en) 2008-05-09 2009-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
WO2009148896A2 (en) 2008-05-29 2009-12-10 Nuclea Biotechnologies, LLC Anti-phospho-akt antibodies
JOP20190083A1 (ar) 2008-06-04 2017-06-16 Amgen Inc بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
EP2282770B1 (en) 2008-06-04 2018-03-07 MacroGenics, Inc. Antibodies with altered binding to fcrn and methods of using same
WO2009156994A1 (en) * 2008-06-24 2009-12-30 Hadasit Medical Research Services And Development Ltd. Ccl20-specific antibodies for cancer therapy
RU2567100C2 (ru) 2008-06-25 2015-10-27 ИЭсБиЭйТЕК, ЭН АЛЬКОН БАЙОМЕДИКАЛ РИСЕРЧ ЮНИТ ЭлЭлСи СТАБИЛЬНЫЕ И РАСТВОРИМЫЕ АНТИТЕЛА, ИНГИБИРУЮЩИЕ TNFα
PT3722310T (pt) 2008-06-25 2024-11-12 Novartis Ag Anticorpos estáveis e solúveis que inibem o vegf
RU2011102743A (ru) * 2008-06-26 2012-08-10 Дана-Фарбер Кэнсер Инститьют, Инк. (Us) Характерные признаки и детерминанты, связанные с метастазированием, и способы их применения
CA2729012A1 (en) 2008-06-27 2009-12-30 Amgen Inc. Ang-2 inhibition to treat multiple sclerosis
CN102137938B (zh) * 2008-07-04 2015-01-21 解码遗传学私营有限责任公司 预测精神分裂症的风险的拷贝数变异
KR20110036608A (ko) 2008-07-07 2011-04-07 디코드 제네틱스 이에이치에프 유방암 위험도 평가를 위한 유전적 변이
EP2405022A3 (en) 2008-07-08 2012-05-02 Genomic Health, Inc. Gene expression profiling for predicting the survivability of prostate cancer subjects
DK2318832T3 (da) 2008-07-15 2014-01-20 Academia Sinica Glycan-arrays på PTFE-lignende aluminiumcoatede objektglas og relaterede fremgangsmåder
ES2433691T3 (es) 2008-07-17 2013-12-12 Ikfe Institut Für Klinische Forschung Und Entwicklung Gmbh Biomarcadores para la insulinorresistencia y disfunción de células beta
EP2338051B1 (en) 2008-07-17 2013-11-20 IKFE Institut für klinische Forschung und Entwicklung GmbH Biomarkers for cardiodiabetes
US20100021472A1 (en) * 2008-07-25 2010-01-28 Geetha Srikrishna Methods for diagnosing and treating cancer
US8795981B2 (en) * 2008-08-08 2014-08-05 Molecular Devices, Llc Cell detection
EP4235181A3 (en) 2008-08-11 2024-02-28 Banyan Biomarkers Inc Biomarker detection process and assay of neurological condition
AU2009280807A1 (en) * 2008-08-12 2010-02-18 Decode Genetics Ehf Genetic variants useful for risk assessment of thyroid cancer
WO2010018601A2 (en) * 2008-08-15 2010-02-18 Decode Genetics Ehf Genetic variants predictive of cancer risk
MX2011001900A (es) 2008-08-18 2011-08-17 Seoul Nat Univ Ind Foundation Metodo para controlar metastasis de cancer o migracion de celulas de cancer modulando el nivel celular de lisil-tarn sintetasa.
RS54233B1 (sr) 2008-08-25 2015-12-31 Amplimmune Inc. Kompozicije pd-1 antagonista i postupci za njihovu primenu
US20110159023A1 (en) 2008-08-25 2011-06-30 Solomon Langermann Pd-1 antagonists and methods for treating infectious disease
KR101442323B1 (ko) 2008-09-07 2014-09-25 글라이코넥스 인코포레이티드 항-연장된 ⅰ형 글라이코스핑고지질 항체, 이의 유도체 및 용도
BRPI0913476A2 (pt) 2008-09-10 2015-12-01 Genentech Inc "usos de um antagonista tspan12 e usos de um antagonista de norrin"
EP2334826A4 (en) 2008-09-12 2012-01-25 Cancer Res Initiative Foundation PROCEDURE FOR THE DETECTION AND DIAGNOSIS OF ORAL AND NASOPHARYNGEAL TUMORS
US8417011B2 (en) 2008-09-18 2013-04-09 Molecular Devices (New Milton) Ltd. Colony detection
US20110200525A1 (en) * 2008-10-09 2011-08-18 Patz Jr Edward F Vhh antibody fragments for use in the detection and treatment of cancer
EP2358749B1 (en) 2008-10-10 2018-07-18 Amgen, Inc Fgf21 mutants and uses thereof
AU2009303453B2 (en) 2008-10-14 2015-02-26 Dyax Corp. Use of IGF-II/IGF-IIE binding for the treatment and prevention of systemic sclerosis associated pulmonary fibrosis
US8147847B2 (en) * 2008-10-21 2012-04-03 International Vaccine Institute Shigella protein antigens and methods
US8871202B2 (en) 2008-10-24 2014-10-28 Lpath, Inc. Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
KR20110081282A (ko) 2008-11-05 2011-07-13 와이어쓰 엘엘씨 베타―용혈성 연쇄구균 (ｂｈｓ) 질환의 예방을 위한 다성분 면역원성 조성물
NZ614351A (en) 2008-11-10 2015-05-29 Alexion Pharma Inc Methods and compositions for treating complement-associated disorders
AT507604A1 (de) 2008-11-19 2010-06-15 Affiris Forschungs & Entwicklungs Gmbh Behandlung von atherosklerose
EP2189539B2 (en) * 2008-11-21 2018-06-13 Chimera Biotec GmbH Conjugate complexes for analyte detection
CA2744555A1 (en) 2008-11-26 2010-06-03 Five Prime Therapeutics, Inc. Compositions and methods for regulating collagen and smooth muscle actin expression by serpine2
WO2010061393A1 (en) 2008-11-30 2010-06-03 Compugen Ltd. He4 variant nucleotide and amino acid sequences, and methods of use thereof
CA2745603A1 (en) 2008-12-03 2010-06-10 Proyecto De Biomedicina Cima, S.L. Use of phenol soluble modulins for the development of vaccines
CA2743707A1 (en) 2008-12-04 2010-06-10 Pioneer Hi-Bred International, Inc. Methods and compositions for enhanced yield by targeted expression of knotted1
US8436145B2 (en) 2008-12-04 2013-05-07 Yeda Research And Development Co. Ltd. Compositions and methods for diagnosing and treating cancer and neurodegenerative diseases related to Beclin-1
US20100256196A1 (en) 2008-12-04 2010-10-07 Ikfe Biomarkers for Atherosclerosis
US20110229905A1 (en) * 2008-12-04 2011-09-22 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Compositions and methods for diagnosing and treating cancer and neurodegenerative diseases rlated to beclin-1
CN102300874B (zh) 2008-12-08 2015-08-05 卡姆普根有限公司 Tmem154多肽和多核苷酸及其作为产生药物和生物制品的药物靶标的用途
AU2009325962A1 (en) 2008-12-11 2011-07-28 Ikfe Institut Fur Klinische Forschung Und Entwicklung Gmbh Biomarkers for insulin sensitizer drug response
WO2010076655A1 (en) 2008-12-30 2010-07-08 Ikfe Gmbh Biomarkers for adipose tissue activity
WO2010079428A2 (en) 2009-01-07 2010-07-15 Ikfe Gmbh Biomarkers for appetite regulation
EP2392351A4 (en) 2009-01-28 2012-12-12 Univ Tokai Educational System INHIBITOR OF HIV REPLICATION AND USE
DK2391653T3 (en) 2009-01-28 2015-02-09 Ind Tech Res Inst Biomarkers associated nephropathy
ES2805347T3 (es) 2009-02-11 2021-02-11 Caris Mpi Inc Perfilado molecular de tumores
US20110014190A1 (en) 2009-02-12 2011-01-20 Human Genome Sciences, Inc. Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance
AU2010213578B2 (en) 2009-02-12 2015-01-29 Cell Signaling Technology, Inc. Mutant ROS expression in human cancer
PL2939683T3 (pl) 2009-02-16 2017-07-31 Cerenis Therapeutics Holding Sa Mimetyki apolipoproteiny A-I
US20100248265A1 (en) * 2009-02-27 2010-09-30 The Salk Institute For Biological Studies Compositions and methods for diagnosis and treatment of cancer
US8772238B2 (en) 2009-03-18 2014-07-08 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Use of ixolaris, a tissue factor inhibitor, for the treatment of cancer
EP2233496A1 (en) 2009-03-26 2010-09-29 Ruhr-Universität Bochum Fluorescent proteins
PT2411410E (pt) * 2009-03-27 2015-10-09 Gojo Ind Inc Composições e métodos para screening e utilização de compostos que antagonizam interações esporo-superfície
WO2010112033A2 (en) 2009-03-31 2010-10-07 Østjysk Innovation A/S Method for estimating the risk of having or developing multiple sclerosis using sequence polymorphisms in a specific region of chromosome x
AU2010231494B2 (en) 2009-04-03 2016-01-07 Decode Genetics Ehf Genetic markers for risk management of atrial fibrillation and stroke
PL3248610T3 (pl) 2009-05-05 2024-04-02 Amgen Inc. Mutanty fgf21 i ich zastosowania
US20120052069A1 (en) 2009-05-05 2012-03-01 Amgen Inc Fgf21 mutants and uses thereof
EP2451975A4 (en) * 2009-05-08 2013-08-14 Decode Genetics Ehf GENETIC VARIANTS CONTRIBUTING TO A RISK OF PROSTATE CANCER
AU2010262927A1 (en) * 2009-06-17 2012-01-19 Amgen Inc. Chimeric FGF19 polypeptides and uses thereof
CA2766309A1 (en) 2009-06-25 2010-12-29 Savient Pharmaceuticals, Inc. Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
IL199618A0 (en) 2009-06-29 2010-04-29 Two To Biotech Ltd Novel antibodies and their use in diagnostic methods
WO2011000805A1 (en) 2009-06-29 2011-01-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Biomarkers of oocyte competency and method of use
JP5766188B2 (ja) 2009-07-01 2015-08-19 プロチバ バイオセラピューティクス インコーポレイティッド 固形腫瘍に治療剤を送達するための脂質製剤
IE20090514A1 (en) 2009-07-06 2011-02-16 Opsona Therapeutics Ltd Humanised antibodies and uses therof
US8796182B2 (en) 2009-07-10 2014-08-05 Decode Genetics Ehf. Genetic markers associated with risk of diabetes mellitus
WO2011004379A1 (en) 2009-07-10 2011-01-13 Tel Hashomer Medical Research Infrastructure And Services Ltd. Compositions and methods for treating cancer
JP2012533322A (ja) 2009-07-20 2012-12-27 ジェネンテック， インコーポレイテッド クローン病のための遺伝子発現マーカー
WO2011011447A1 (en) 2009-07-20 2011-01-27 Protiva Biotherapeutics, Inc. Compositions and methods for silencing ebola virus gene expression
EP2459742B1 (en) 2009-07-29 2016-04-06 Pharnext New diagnostic tools for alzheimer disease
IL200202A0 (en) 2009-08-02 2010-05-31 Orly Devary Novel proteins
JP2013501057A (ja) 2009-08-03 2013-01-10 ユニバーシティー・オブ・マイアミ 制御性ｔ細胞のｉｎｖｉｖｏにおける増殖
US20120148604A1 (en) 2009-08-20 2012-06-14 Transposagen Biopharmaceuticals, Inc. Trp inhibitors and uses thereof
WO2011026036A1 (en) * 2009-08-28 2011-03-03 Inova Diagnostics, Inc. Detecting circulating cartilage oligomeric matrix protein in liver cirrhosis
CN102741279A (zh) 2009-08-31 2012-10-17 艾普利穆恩公司 B7-h4融合蛋白和其使用方法
DK2477652T3 (en) 2009-09-16 2015-07-20 Vaxart Inc Immunization strategy for the prevention of infection H1Ni
EP2480668A2 (en) 2009-09-23 2012-08-01 Protiva Biotherapeutics Inc. Compositions and methods for silencing genes expressed in cancer
WO2011038301A2 (en) 2009-09-25 2011-03-31 Xoma Technology Ltd. Screening methods
US8926976B2 (en) 2009-09-25 2015-01-06 Xoma Technology Ltd. Modulators
WO2011041640A1 (en) * 2009-10-01 2011-04-07 Alcon Research, Ltd. Olopatadine compositions and uses thereof
ES2666372T3 (es) 2009-10-11 2018-05-04 Biogen Ma Inc. Ensayos relacionados con anti-VLA-4
EP2488659B1 (en) 2009-10-15 2019-12-11 Crescendo Bioscience, Inc. Biomarkers and methods for measuring and monitoring inflammatory disease activity
US20120263719A1 (en) 2009-10-22 2012-10-18 Yeda Research And Development Co., Ltd. Compositions and methods for treating aspergillosis
AU2010310545C1 (en) 2009-10-23 2015-04-30 Amgen British Columbia Anti-GCC antibody molecules and related compositions and methods
SI2494356T1 (sl) * 2009-10-26 2017-07-31 Genentech, Inc. Preizkusi za detektiranje protiteles, specifičnih za terapevtska protitelesa proti IgE, in njihova uporaba pri anafilaksi
EP2494077A4 (en) 2009-10-27 2013-08-21 Caris Mpi Inc MOLECULAR PROFILING FOR PERSONALIZED MEDICINE
EP2494364A1 (en) 2009-10-29 2012-09-05 Tethys Bioscience, Inc. Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes
JP2013509587A (ja) 2009-10-29 2013-03-14 テシス バイオサイエンス， インコーポレイテッド 糖尿病のリスクを決定する方法
WO2011058367A2 (en) 2009-11-13 2011-05-19 Astrazeneca Ab Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
WO2011067711A2 (en) 2009-12-01 2011-06-09 Compugen Ltd Novel heparanase splice variant
US8372952B2 (en) * 2009-12-02 2013-02-12 Amgen Inc. Binding proteins that bind to human FGFR1C, human β-klotho and both human FGFR1C and human β-klotho
US11377485B2 (en) 2009-12-02 2022-07-05 Academia Sinica Methods for modifying human antibodies by glycan engineering
US10087236B2 (en) 2009-12-02 2018-10-02 Academia Sinica Methods for modifying human antibodies by glycan engineering
UA109888C2 (uk) 2009-12-07 2015-10-26 ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
CA2779562C (en) 2009-12-07 2019-12-31 Pieris Ag Muteins of human lipocalin 2 (lcn2, hngal) with affinity for a given target
US9689801B2 (en) 2009-12-22 2017-06-27 Agency For Science, Technology And Research SERS-based analyte detection
WO2011076922A1 (en) 2009-12-23 2011-06-30 Synimmune Gmbh Anti-flt3 antibodies and methods of using the same
HRP20181419T1 (hr) 2010-01-06 2018-11-16 Dyax Corp. Plazma kalikrein vezni proteini
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
IN2012DN06309A (OSRAM) 2010-01-11 2015-09-25 Alexion Pharma Inc
ES3012733T3 (en) 2010-01-11 2025-04-10 Biogen Ma Inc Assay for jc virus antibodies
WO2011089211A1 (en) 2010-01-22 2011-07-28 Synimmune Gmbh Anti-cd133 antibodies and methods of using the same
AU2011354597B2 (en) 2010-01-26 2016-09-22 Bioregency Inc. Compositions and methods relating to argininosuccinate synthetase
WO2011092700A1 (en) 2010-01-27 2011-08-04 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
EP2531261B1 (en) 2010-02-01 2016-08-31 The Board of Trustees of the Leland Stanford Junior University Methods for diagnosis and treatment of non-insulin dependent diabetes mellitus
TWI518325B (zh) 2010-02-04 2016-01-21 自治醫科大學 對ａｌｋ抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
JP4686639B1 (ja) * 2010-02-25 2011-05-25 田中貴金属工業株式会社 生豚肉検出法およびその検出キット
WO2011106738A2 (en) 2010-02-25 2011-09-01 Fred Hutchinson Cancer Research Center Use of tcr clonotypes as biomarkers for disease
US20110212088A1 (en) * 2010-02-26 2011-09-01 Sabbadini Roger A Anti-paf antibodies
WO2011109398A2 (en) 2010-03-02 2011-09-09 President And Fellows Of Harvard College Methods and compositions for treatment of angelman syndrome and autism spectrum disorders
US20110237000A1 (en) * 2010-03-11 2011-09-29 Agency For Science, Technology And Research Method for detecting an analyte molecule
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
MX342017B (es) 2010-03-26 2016-09-09 Dartmouth College Proteina mediadora de celula t regulatoria vista, agentes de enlace de vista y uso de los mismos.
EP2556169B1 (en) 2010-04-07 2018-02-14 Imperial Innovations Limited Methods for categorising cancer such as breast cancer
WO2011130332A1 (en) 2010-04-12 2011-10-20 Academia Sinica Glycan arrays for high throughput screening of viruses
MX2012011986A (es) 2010-04-15 2013-03-05 Amgen Inc RECEPTOR FGF HUMANO Y PROTEINAS ENLAZADAS A ß-KLOTHO.
CA2796601C (en) 2010-04-19 2019-03-26 Research Development Foundation Rtef-1 variants and uses thereof
CN103119444B (zh) 2010-04-21 2016-10-26 米密德诊断学有限公司 区分细菌与病毒感染的标记物和决定因素以及其使用方法
SMT202000095T1 (it) 2010-05-14 2020-03-13 Amgen Inc Formulazioni di anticorpi anti-sclerostina ad alta concentrazione
CN103118701B (zh) 2010-05-14 2017-10-24 百深公司 Ospa嵌合体及其在疫苗中的用途
EP2572197A4 (en) 2010-05-18 2013-08-28 Texas A & M Univ Sys METHOD AND COMPOSITIONS FOR DIAGNOSIS AND MONITORING OF INFLAMMATORY DISEASES
WO2011146725A1 (en) 2010-05-19 2011-11-24 Bayer Healthcare Llc Biomarkers for a multikinase inhibitor
WO2011145085A2 (en) 2010-05-21 2011-11-24 Procognia (Israel) Ltd Novel antibodies and methods of use for the treatment and diagnosis of cancer
WO2011161545A2 (en) 2010-06-04 2011-12-29 The Netherlands Cancer Institute Non-hydrolyzable protein conjugates, methods and compositions related thereto
WO2011156715A2 (en) 2010-06-10 2011-12-15 The Regents Of The University Of Michigan Methods of treating metabolic disorders and cardiovascular diseases
GB201009798D0 (en) 2010-06-11 2010-07-21 Immunovia Ab Method,array and use thereof
EP2585476A4 (en) 2010-06-22 2014-01-22 Neogenix Oncology Inc ANTIGENS AND ANTIBODIES SPECIFIC TO COLON AND PANCREATIC CANCER
JP2013538555A (ja) 2010-07-15 2013-10-17 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド Ｍｈｃクラスｉｉとグルタミン酸デカルボキシラーゼ（ｇａｄ）自己抗原性ペプチドとの天然型複合体に対するｔ細胞受容体様特異性を有する単離された高親和性実体
JP2013535963A (ja) 2010-07-15 2013-09-19 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド Ｍｈｃクラスｉｉと糖尿病関連自己抗原性ペプチドとの天然型複合体に対するｔ細胞受容体様特異性を有する単離された高親和性実体
CA2807440A1 (en) 2010-08-04 2012-02-09 Cizzle Biotechnology Limited Methods and compounds for the diagnosis and treatment of cancer
US20120101108A1 (en) 2010-08-06 2012-04-26 Cell Signaling Technology, Inc. Anaplastic Lymphoma Kinase In Kidney Cancer
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
EP2606165B1 (en) 2010-08-16 2016-10-12 Sinai Health System Markers of the male urogenital tract
EP3192880B1 (en) 2010-08-18 2019-10-09 Fred Hutchinson Cancer Research Center Nucleic acid agents for use in treating facioscapulohumeral dystrophy (fshd)
US10088490B2 (en) 2010-08-20 2018-10-02 Siemens Healthcare Diagnostics Inc. Assay for analytes using multiple receptors
HUE034544T2 (hu) 2010-08-23 2018-02-28 Wyeth Llc Neisseria meningitidis rLP2086 antigént tartalmazó stabil készítmények
WO2012030738A2 (en) 2010-08-30 2012-03-08 Beckman Coulter, Inc. Complex phosphoprotein activation profiles
US9982304B2 (en) 2010-09-03 2018-05-29 The Johns Hopkins University ARID1A and PPP2R1A mutations in cancer
GB201014837D0 (en) 2010-09-07 2010-10-20 Immunovia Ab Biomarker signatures and uses thereof
JP5976652B2 (ja) 2010-09-10 2016-08-24 ワイス・エルエルシー 髄膜炎菌ｏｒｆ２０８６抗原の非脂質化変異体
WO2012035518A1 (en) 2010-09-17 2012-03-22 Compugen Ltd. Compositions and methods for treatment of drug resistant multiple myeloma
WO2012038744A2 (en) 2010-09-22 2012-03-29 Genome Research Limited Detecting mutations
CA2812556C (en) 2010-09-23 2023-02-14 Xue-Ping Wang Colon and pancreas cancer peptidomimetics
US8497138B2 (en) 2010-09-30 2013-07-30 Genetix Limited Method for cell selection
US9006458B2 (en) 2010-10-12 2015-04-14 Agency For Science, Technology And Research Surface Enhanced Raman Spectroscopy (SERS) compounds and methods of their preparation
EP2444084A1 (en) 2010-10-21 2012-04-25 Centro Nacional de Investigaciones Oncológicas (CNIO) Use of PI3K inibitors for the treatment of obesity
CA2815416A1 (en) 2010-10-21 2012-04-26 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
UY33679A (es) 2010-10-22 2012-03-30 Esbatech Anticuerpos estables y solubles
GB201018014D0 (en) 2010-10-26 2010-12-08 Senzagen Ab Analytical methods and arrays for use in the same
EP2632956B1 (en) 2010-10-28 2018-06-20 Yeda Research and Development Co. Ltd. Methods of generating antibodies to metalloenzymes
US8361720B2 (en) 2010-11-15 2013-01-29 Exact Sciences Corporation Real time cleavage assay
WO2012068355A2 (en) 2010-11-18 2012-05-24 Tufts Medical Center, Inc. Treating aortic aneurysm by modulating toll-like receptors
PE20141173A1 (es) 2010-11-23 2014-09-25 Pantheryx Inc Composiciones y metodos para el tratamiento en aplicaciones clinicas de amplio espectro, no diferenciadas o combinadas
EP2643018B1 (en) 2010-11-23 2020-10-14 AlderBio Holdings LLC Anti-il-6 antibodies for the treatment of oral mucositis
EP2477032A1 (en) 2011-01-18 2012-07-18 Baxter International Inc Measurement of anti-amyloid antibodies in human blood
KR20130139153A (ko) 2011-01-18 2013-12-20 백스터 인터내셔널 인코포레이티드 인간 혈액 중 항-베타 아밀로이드 항체의 측정
US9447187B2 (en) 2011-02-03 2016-09-20 Alexion Pharmaceuticals, Inc. Use of an anti-CD200 antibody for prolonging the survival of allografts
FR2971258B1 (fr) 2011-02-09 2020-12-04 Bio Rad Pasteur Combinaison de biomarqueurs pour le pronostic d'une reponse ou non-reponse a un traitement anti-vhc
FR2971256B1 (fr) 2011-02-09 2024-09-27 Bio Rad Pasteur Combinaison de biomarqueurs pour la detection et l'evaluation d'une fibrose hepatique
FR2971257B1 (fr) 2011-02-09 2020-12-04 Bio Rad Pasteur Combinaison de biomarqueurs pour le pronostic d'une reponse ou non-reponse a un traitement anti-vhc
EP2675473A1 (en) 2011-02-15 2013-12-25 Immune Design Corp. Methods for enhancing immunogen specific immune responses by vectored vaccines
CN102675460B (zh) 2011-02-28 2015-08-19 珠海市丽珠单抗生物技术有限公司 抗肿瘤坏死因子α的人源化抗体
US8658171B2 (en) 2011-02-28 2014-02-25 Livzon Mabpharm Inc. Humanized anti-TNFα antibodies
CA2828000A1 (en) 2011-03-01 2012-09-07 Amgen Inc. Bispecific binding agents
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
WO2012125623A2 (en) 2011-03-14 2012-09-20 Ludwig Institute For Cancer Research Ltd. Cleavage inhibitors of transforming growth factor beta type i receptor and uses thereof in cancer therapy
AR085911A1 (es) 2011-03-16 2013-11-06 Sanofi Sa Dosis terapeutica segura de una proteina similar a un anticuerpo con region v dual
JP2014511842A (ja) 2011-03-25 2014-05-19 アムジエン・インコーポレーテツド 抗スクレロスチン抗体結晶およびその製剤
WO2012141984A1 (en) 2011-04-08 2012-10-18 Immune Design Corp. Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
JP2014513289A (ja) 2011-04-08 2014-05-29 バイオジェン・アイデック・エムエイ・インコーポレイテッド ＩＦＮβに対する治療応答性を予測するバイオマーカーおよびその使用
US9150644B2 (en) 2011-04-12 2015-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
RU2623161C2 (ru) 2011-04-15 2017-06-22 Компуджен Лтд. Полипептиды и полинуклеотиды и их применение для лечения иммунологических нарушений и рака
US20140065164A1 (en) 2011-04-29 2014-03-06 Bristol-Myers Squibb Company Ip-10 antibody dosage escalation regimens
SG194793A1 (en) 2011-05-06 2013-12-30 Nvip Pty Ltd Anti-nerve growth factor antibodies and methods of preparing and using the same
RU2640252C2 (ru) 2011-05-06 2017-12-27 Нексвет Австралия Пти Лтд Антитела против фактора роста нервов и способы их получения и применения
HUE057288T2 (hu) 2011-05-06 2022-04-28 Zoetis Services Llc Idegi növekedési faktor elleni ellenanyagok és eljárások elõállításukra és alkalmazásukra
GB201114858D0 (en) 2011-08-29 2011-10-12 Nvip Pty Ltd Anti-nerve growth factor antibodies and methods of using the same
CA2835094C (en) 2011-05-06 2020-12-22 David Gearing Anti-nerve growth factor antibodies and methods of preparing and using the same
WO2012156825A1 (en) 2011-05-17 2012-11-22 Genoscience Pharma Peptide-based hiv pre-integration complex inhibitors
TWI560200B (en) 2011-05-25 2016-12-01 Innate Pharma Sa Anti-kir antibodies for the treatment of inflammatory and autoimmune disorders
KR102039751B1 (ko) 2011-05-31 2019-11-01 바이오젠 엠에이 인코포레이티드 Pml의 위험을 판단하는 방법
EP2714084B1 (en) 2011-06-02 2019-05-22 Dyax Corp. Fc RECEPTOR BINDING PROTEINS
JP2014527036A (ja) 2011-06-27 2014-10-09 ザ ジャクソン ラボラトリー 癌および自己免疫疾患の処置のための方法および組成物
AU2012277376B2 (en) 2011-06-30 2016-11-24 Compugen Ltd. Polypeptides and uses thereof for treatment of autoimmune disorders and infection
EP2734543B1 (en) 2011-07-24 2018-10-03 Carmel-Haifa University Economic Corp. Lactoferrin fragments and use thereof
EP2737318B1 (en) 2011-07-27 2017-03-01 Bio-Rad Innovations A2m fragments and applications thereof
RU2014102935A (ru) 2011-08-02 2015-09-10 Пфайзер Инк. Кризотиниб для применения в лечении рака
EP2739975B1 (en) 2011-08-03 2015-06-17 Quidel Corporation N-acetyl-d-glucosamine for enhanced specificity of strep a immunoassay
HUE039786T2 (hu) 2011-08-04 2019-02-28 Amgen Inc Csonthiány-defektusok kezelési módszere
SG10201606991RA (en) 2011-08-23 2016-10-28 Foundation Medicine Inc Novel kif5b-ret fusion molecules and uses thereof
CN103958545A (zh) 2011-08-30 2014-07-30 Nvip私人有限公司 犬源化肿瘤坏死因子抗体及其使用方法
JP6166263B2 (ja) 2011-09-22 2017-07-19 メディシナル バイオコンバージェンス リサーチ センター ロイシンｔＲＮＡ合成酵素の新規用途（ＮｏｖｅｌｕｓｅｏｆｌｅｕｃｙｌｔＲＮＡｓｙｎｔｈｅｔａｓｅ）
WO2013045863A1 (fr) 2011-09-29 2013-04-04 Institut Pasteur Detection de souches e.coli de serotype o104
EP2581384A1 (en) 2011-10-11 2013-04-17 Institut Pasteur Products useful for the treatment of malignant neoplasms of the human nervous system
CA2850032C (en) 2011-10-14 2022-06-07 Genentech, Inc. Anti-htra1 antibodies and methods of use
WO2013056178A2 (en) 2011-10-14 2013-04-18 Foundation Medicine, Inc. Novel estrogen receptor mutations and uses thereof
BR112014009310A2 (pt) 2011-10-17 2017-04-11 Westfaelische Wilhelms-Universitaet Muenster métodos de avaliação de riscos de lmp e aparelhos relacionados
JP6338530B2 (ja) 2011-11-10 2018-06-06 ジェネンテック， インコーポレイテッド アルツハイマー病を治療、診断、および監視するための方法
WO2013071066A1 (en) 2011-11-11 2013-05-16 The Broad Institute, Inc. Signatures associated with the response to cancer therapy
WO2013075031A1 (en) 2011-11-16 2013-05-23 Becton, Dickinson And Company Methods and systems for detecting an analyte in a sample
US9554736B2 (en) 2011-11-29 2017-01-31 Teleflex Medical Incorporated Device with integrated allergy testing
WO2013082301A1 (en) 2011-11-29 2013-06-06 Teleflex Medical, Inc. Device with integrated allergy testing
WO2013082308A1 (en) 2011-11-30 2013-06-06 Children's Hospital Medical Center Personalized pain management and anesthesia: preemptive risk identification and therapeutic decision support
CA2857114A1 (en) 2011-11-30 2013-06-06 Genentech, Inc. Erbb3 mutations in cancer
PL2790687T3 (pl) 2011-12-16 2019-03-29 Poseida Therapeutics, Inc. Modulatory trpc4 do stosowania w leczeniu lub zapobieganiu bólowi
US9035039B2 (en) 2011-12-22 2015-05-19 Protiva Biotherapeutics, Inc. Compositions and methods for silencing SMAD4
CN104039805B (zh) 2011-12-22 2016-11-16 糖模拟物有限公司 E-选择蛋白拮抗剂化合物、组合物及使用方法
IN2014CN04634A (OSRAM) 2011-12-28 2015-09-18 Amgen Inc
WO2013098813A1 (en) 2012-01-01 2013-07-04 Qbi Enterprises Ltd. Endo180-targeted particles for selective delivery of therapeutic and diagnostic agents
RU2663141C2 (ru) 2012-01-20 2018-08-01 Джензим Корпорейшн Анти-cxcr3 антитела
CA2862499C (en) 2012-01-24 2020-10-27 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
BR112014018481A2 (pt) 2012-02-01 2017-07-04 Compugen Ltd anticorpo monoclonal ou policlonal ou um fragmento de ligação a antígeno do mesmo, polinucleotídeo, anticorpo monoclonal, vetor, hibridoma, anticorpo, hibridoma 5166-2 e/ou 5166-9, anticorpo ou fragmento de ligação a antígeno, composição farmacêutica, uso do anticorpo ou fragmento de ligação a anticorpo, método para tratar câncer, método para diagnosticar câncer em um indivíduo, anticorpo, método, composição ou uso
ES2679107T3 (es) 2012-02-09 2018-08-22 Memed Diagnostics Ltd. Distintivos y determinantes para diagnosticar infecciones y métodos para usarlos
KR20220045089A (ko) 2012-02-24 2022-04-12 아뷰터스 바이오파마 코포레이션 트리알킬 양이온성 지질 및 그의 사용 방법
KR101784644B1 (ko) 2012-03-09 2017-10-11 화이자 인코포레이티드 수막염균 조성물 및 이의 사용 방법
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
WO2013142796A2 (en) 2012-03-23 2013-09-26 Bristol-Myers Squibb Company Methods of treatments using ctla4 antibodies
US9592289B2 (en) 2012-03-26 2017-03-14 Sanofi Stable IgG4 based binding agent formulations
RU2014143251A (ru) 2012-03-28 2016-05-20 Дженентек, Инк. Антиидиотипические антитела к hcmv и их применение
EP2647995B8 (en) 2012-04-02 2015-02-18 Roche Diagnostics GmbH Methods and use for assessing chronic obstructive pulmonary disease (COPD) severity
US10130714B2 (en) 2012-04-14 2018-11-20 Academia Sinica Enhanced anti-influenza agents conjugated with anti-inflammatory activity
DK2838998T3 (en) 2012-04-18 2018-01-15 Cell Signaling Technology Inc EGFR AND ROS1 IN CANCER
US9156915B2 (en) 2012-04-26 2015-10-13 Thomas Jefferson University Anti-GCC antibody molecules
GB201207297D0 (en) 2012-04-26 2012-06-06 Senzagen Ab Analytical methods and arrays for use in the same
WO2013170051A1 (en) 2012-05-09 2013-11-14 Advanced Animal Diagnostics, Inc. Sample cartridge and sample stage
JP6377054B2 (ja) 2012-05-11 2018-08-22 リセット セラピューティークス， インコーポレイテッド クリプトクロム調節薬としてのカルバゾール含有スルホンアミド
WO2013180652A1 (en) 2012-05-31 2013-12-05 Agency For Science, Technology And Research Surface enhanced raman spectroscopy (sers) marker conjugates and methods of their preparation
US10155987B2 (en) 2012-06-12 2018-12-18 Dana-Farber Cancer Institute, Inc. Methods of predicting resistance to JAK inhibitor therapy
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
TWI677507B (zh) 2012-06-22 2019-11-21 達特茅斯學院基金會 新穎之ｖｉｓｔａ－ｉｇ構築體及ｖｉｓｔａ－ｉｇ用於治療自體免疫、過敏及發炎病症之用途
JP6770312B2 (ja) 2012-07-05 2020-10-14 ユセベ ファルマ ソシエテ アノニム 骨疾患の治療
DE102012013888A1 (de) 2012-07-09 2014-05-22 Schebo Biotech Ag Testkit (Kombi-Schnelltest) zum synchronen Nachweis von Biomarkern im Stuhl zur Erkennung pathologischer Veränderungen im Gastrointestinaltrakt, insbesondere im Darm
DE202012012084U1 (de) 2012-07-09 2013-04-15 Schebo Biotech Ag Testkit (Kombi-Schnelltest) zum synchronen Nachweis von Biomarkern im Stuhl zur Erkennung pathologischer Veränderungen im Gastrointestinaltrakt, insbesondere im Darm
US9610324B2 (en) 2012-07-11 2017-04-04 Esperion Therapeutics, Inc. Apolipoprotein mixtures
EP2687850A1 (en) 2012-07-19 2014-01-22 Roche Diagniostics GmbH Methods of stratifying for respiratory support therapy
WO2014015217A1 (en) 2012-07-19 2014-01-23 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
WO2014018375A1 (en) 2012-07-23 2014-01-30 Xenon Pharmaceuticals Inc. Cyp8b1 and uses thereof in therapeutic and diagnostic methods
JP2015524802A (ja) 2012-07-27 2015-08-27 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ キメラｏｓｐａ分子を含む組成物およびその使用方法
CA2880764C (en) 2012-08-03 2022-08-30 Foundation Medicine, Inc. Human papilloma virus as predictor of cancer prognosis
EP2885319B1 (en) 2012-08-14 2019-10-09 Nanyang Technological University Angiopoietin-like 4 antibody and a method of its use in cancer treatment
WO2014028572A2 (en) 2012-08-15 2014-02-20 The Procter & Gamble Company Systems, models and methods for identifying and evaluating skin-active agents effective for treating an array of skin disorders
CA2880701A1 (en) 2012-08-18 2014-02-27 Academia Sinica Cell-permeable probes for identification and imaging of sialidases
US20140056901A1 (en) 2012-08-21 2014-02-27 The Institute For Molecular Medicine Anti-tau antibodies and compositions for and methods of making and using in treatment, diagnosis and monitoring of tauopathies
AU2013312211B2 (en) 2012-09-07 2018-03-29 King's College London VISTA modulators for diagnosis and treatment of cancer
JP6502851B2 (ja) 2012-09-10 2019-04-17 ヴェストファーリッシュ ヴィルヘルム−ユニバーシテート ミュンスター 炎症性状態の予防、処置、および診断のための方法および化合物
US10288626B2 (en) 2012-09-14 2019-05-14 University Of Kentucky Research Foundation Secreted tumor-associated cytochrome as a blood-based biomarker for cancer
WO2014043633A1 (en) 2012-09-17 2014-03-20 Agios Pharmaceuticals, Inc. Use of e-cadherin and vimentin for selection of treatment responsive patients
WO2014047285A1 (en) 2012-09-19 2014-03-27 Paraskevi Giannakakou Identifying taxane sensitivity in prostate cancer patients
EP2906954B1 (en) 2012-10-09 2018-04-11 Ramot at Tel-Aviv University Ltd. Methods and kits for predicting prognosis of cancer using soluble mortalin in blood
WO2014063205A1 (en) 2012-10-26 2014-05-01 The University Of Queensland Use of endocytosis inhibitors and antibodies for cancer therapy
US11230589B2 (en) 2012-11-05 2022-01-25 Foundation Medicine, Inc. Fusion molecules and uses thereof
WO2014071358A2 (en) 2012-11-05 2014-05-08 Foundation Medicine, Inc. Novel ntrk1 fusion molecules and uses thereof
KR20150087270A (ko) 2012-11-05 2015-07-29 프로나이 테라퓨틱스, 인코포레이티드 Bcl2 발현 조절에 의한 암치료용 바이오마커 이용 방법
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
JP6333280B2 (ja) 2012-11-21 2018-05-30 アジオス ファーマシューティカルズ， インコーポレイテッド グルタミナーゼ阻害剤およびその使用方法
WO2014079011A1 (en) 2012-11-22 2014-05-30 Agios Pharmaceuticals, Inc. Heterocyclic compounds for inhibiting glutaminase and their methods of use
PL2928476T3 (pl) 2012-12-07 2018-07-31 Glycomimetics, Inc. Związki, kompozycje i sposoby wykorzystujące antagonistów e-selektyny do mobilizacji komórek hematopoietycznych
GB201223053D0 (en) 2012-12-20 2013-02-06 Medical Res Council Receptor
JP6576831B2 (ja) 2012-12-28 2019-09-18 プレシジョン・バイオロジクス・インコーポレイテッド 結腸癌及び膵臓癌の診断ならびに治療のための、ヒト化モノクローナル抗体及び使用方法
EP2941644B1 (en) 2013-01-02 2019-09-11 Qiagen Sciences, LLC Methods for predicting time-to-delivery in pregnant women
EP2943253B1 (en) 2013-01-09 2021-10-20 University Of Miami Compositions and methods for the regulation of t regulatory cells using tl1a-ig fusion protein and il-2
WO2014113729A2 (en) 2013-01-18 2014-07-24 Foundation Mecicine, Inc. Methods of treating cholangiocarcinoma
WO2014122166A1 (en) 2013-02-06 2014-08-14 Pieris Ag Novel lipocalin-mutein assays for measuring hepcidin concentration
EP2964665B1 (en) 2013-03-08 2018-08-01 Pfizer Inc Immunogenic fusion polypeptides
PE20151873A1 (es) 2013-03-14 2016-01-06 Kasing Cheng Sistema de carcasa de tira de prueba
US9151747B1 (en) 2013-03-14 2015-10-06 Mercyhurst University Sucralose antibody and immunoassay
US9052314B2 (en) 2013-03-14 2015-06-09 Silver Lake Research Corporation Biomarkers for detecting the presence of bacteria
US9302005B2 (en) 2013-03-14 2016-04-05 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
CA2907394A1 (en) 2013-03-15 2014-09-18 Velo Bio, Llc Method for treating eclampsia and preeclampsia
PL2970980T3 (pl) 2013-03-15 2019-01-31 Janssen Biotech, Inc Sposoby wytwarzania kontrolujące zawartość C-końcowej lizyny, galaktozy i kwasu sjalowego w rekombinowanych białkach
WO2014140197A1 (en) 2013-03-15 2014-09-18 Westfaelische Wilhelms-Universitaet Muenster Detection of acute renal allograft rejection
CN105228641A (zh) 2013-03-21 2016-01-06 密歇根大学董事会 治疗代谢紊乱的方法
GB201305940D0 (en) 2013-04-02 2013-05-15 Immunovia Ab Methods and arrays for use in the same
GB201306147D0 (en) 2013-04-05 2013-05-22 Univ Ha Il Novel biomarker signature and uses thereof
EP2994167B1 (en) 2013-05-06 2020-05-06 Alnylam Pharmaceuticals, Inc. Dosages and methods for delivering lipid formulated nucleic acid molecules
WO2014193804A1 (en) 2013-05-28 2014-12-04 Biogen Idec Ma Inc. Method of assessing risk of pml
SG11201509742QA (en) 2013-06-03 2015-12-30 Novartis Ag Combinations of an anti-pd-l1 antibody and a mek inhibitor and/or a braf inhibitor
JP2016520846A (ja) * 2013-06-06 2016-07-14 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 多量体の標的分子の検出に対する粒子ベースの試験において凝集を防ぐ試薬、方法及び装置
WO2014210397A1 (en) 2013-06-26 2014-12-31 Academia Sinica Rm2 antigens and use thereof
US9981030B2 (en) 2013-06-27 2018-05-29 Academia Sinica Glycan conjugates and use thereof
WO2015000014A1 (en) 2013-07-01 2015-01-08 Newsouth Innovations Pty Limited Diagnosis and treatment of autoimmune diseases
CA2918225C (en) 2013-07-17 2023-11-21 Foundation Medicine, Inc. Methods of treating urothelial carcinomas
US10227370B2 (en) 2013-08-02 2019-03-12 California Institute Of Technology Heparan sulfate/heparin mimetics with anti-chemokine and anti-inflammatory activity
US9770461B2 (en) 2013-08-02 2017-09-26 California Institute Of Technology Tailored glycopolymers as anticoagulant heparin mimetics
US9782476B2 (en) 2013-09-06 2017-10-10 Academia Sinica Human iNKT cell activation using glycolipids with altered glycosyl groups
EP3042208A4 (en) 2013-09-06 2017-04-19 Theranos, Inc. Systems and methods for detecting infectious diseases
CN105492021B (zh) 2013-09-08 2018-12-04 辉瑞公司 脑膜炎奈瑟氏球菌组合物及其方法
EP3055695A1 (en) 2013-09-12 2016-08-17 Institut National de la Santé et de la Recherche Médicale Method for in vitro quantifying allo-antibodies, auto-antibodies and/or therapeutic antibodies
KR102332302B1 (ko) 2013-09-13 2021-12-01 제넨테크, 인크. 세포주에서 숙주 세포 단백질 및 재조합 폴리펩티드 생성물을 검출 및 정량화하기 위한 조성물 및 방법
KR102373930B1 (ko) 2013-09-13 2022-03-11 제넨테크, 인크. 정제된 재조합 폴리펩티드를 포함하는 방법 및 조성물
KR102100419B1 (ko) 2013-09-13 2020-04-14 베이진 스위찰랜드 게엠베하 항-pd1 항체 및 이의 치료 및 진단 용도
EP3470081A1 (en) 2013-10-01 2019-04-17 Mayo Foundation for Medical Education and Research Methods for treating cancer in patients with elevated levels of bim
WO2015050959A1 (en) 2013-10-01 2015-04-09 Yale University Anti-kit antibodies and methods of use thereof
EP3052102B1 (en) 2013-10-04 2019-12-04 Aptose Biosciences Inc. Compositions for treating cancers
WO2015063604A2 (en) 2013-11-01 2015-05-07 Imberti Luisa BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO IFNβ AND USES THEREOF
GB201319878D0 (en) 2013-11-11 2013-12-25 Immunovia Ab Method, Array and use thereof
AU2014349828B2 (en) 2013-11-15 2021-01-28 Centre National De La Recherche Scientifique A molecular marker of Plasmodium falciparum artemisinin resistance
WO2015078711A2 (en) 2013-11-18 2015-06-04 Westfaelische Wilhelms-Universitaet Muenster Methods, peptides and antibodies for preventing, treating and diagnosing an inflammatory condition
WO2015084625A1 (en) 2013-12-02 2015-06-11 Baylor College Of Medicine Identification of a new polypeptide hormone for maintenance of optimal body weight and blood glucose
US9309314B2 (en) 2013-12-03 2016-04-12 Agency For Science, Technology And Research (A*Star) Polypeptides, nucleic acids and uses thereof
GB201322094D0 (en) 2013-12-13 2014-01-29 Electrophoretics Ltd Methods and compositions relating to alzheimers disease
EP3083670A2 (en) 2013-12-17 2016-10-26 Westfälische Wilhelms-Universität Münster Means and methods for treating a pruritus-like skin-disease
EP2960252A1 (en) 2014-06-26 2015-12-30 Institut Pasteur Phospholipase for treatment of immunosuppression
US10273301B2 (en) 2013-12-24 2019-04-30 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
US10344073B2 (en) 2014-01-09 2019-07-09 Hadasit Medical Research Services And Development Ltd. Cell compositions and methods for cancer therapy
CN106029075A (zh) 2014-01-09 2016-10-12 细胞内治疗公司 有机化合物
US10150818B2 (en) 2014-01-16 2018-12-11 Academia Sinica Compositions and methods for treatment and detection of cancers
US9982041B2 (en) 2014-01-16 2018-05-29 Academia Sinica Compositions and methods for treatment and detection of cancers
US10151754B2 (en) 2014-01-17 2018-12-11 Minomic International Ltd. Cell surface prostate cancer antigen for diagnosis
SG11201605883UA (en) 2014-01-21 2016-08-30 Immune Design Corp Compositions for use in the treatment of allergic conditions
ES2738582T3 (es) 2014-02-14 2020-01-23 Immune Design Corp Inmunoterapia del cáncer a través de combinación de inmunoestimulación local y sistémica
GB201403115D0 (en) 2014-02-21 2014-04-09 Qbd Qs Ip Ltd Red blood cell detection
CA2940422A1 (en) 2014-02-24 2015-08-27 Children's Hospital Medical Center Methods and compositions for personalized pain management
EP3757224A3 (en) 2014-02-27 2021-03-17 Biogen MA Inc. Method of assessing risk of pml
EA201691896A1 (ru) 2014-03-21 2017-01-30 Аджиос Фармасьютикалз, Инк. Соединения и способы их применения
TWI687428B (zh) 2014-03-27 2020-03-11 中央研究院 反應性標記化合物及其用途
SG10201808565QA (en) 2014-03-31 2018-11-29 Debiopharm Int Sa Fgfr fusions
CA2943821A1 (en) 2014-04-02 2015-10-08 Crescendo Bioscience Biomarkers and methods for measuring and monitoring juvenile idiopathic arthritis activity
TWI690521B (zh) 2014-04-07 2020-04-11 美商同步製藥公司 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
US9176113B1 (en) 2014-04-11 2015-11-03 Synapdx Corporation Methods and systems for determining autism spectrum disorder risk
EP3134439B1 (en) 2014-04-21 2018-12-26 Millennium Pharmaceuticals, Inc. Anti-psyk antibody molecules and use of same for syk-targeted therapy
EP3502698A1 (en) 2014-05-05 2019-06-26 MicroBPlex, Inc. Media elaborated with newly synthesized antibodies and uses thereof
WO2015169884A2 (en) 2014-05-07 2015-11-12 Westfaelische Wilhelms-Universitaet Muenster Compounds and methods for the treatment of itch
WO2015172083A1 (en) 2014-05-08 2015-11-12 Biogen Ma Inc. Dimethylfumarate and prodrugs for treatment of multiple sclerosis
US20170269075A1 (en) 2014-05-12 2017-09-21 Biogen Ma Inc. Biomarkers predictive of lupus progression and uses thereof
IL248511B (en) 2014-05-13 2022-07-01 Bavarian Nordic As Combination therapy for treating cancer with a poxvirus expressing a tumor antigen and a monoclonal antibody against tim-3
US10302653B2 (en) 2014-05-22 2019-05-28 Mayo Foundation For Medical Education And Research Distinguishing antagonistic and agonistic anti B7-H1 antibodies
US10118969B2 (en) 2014-05-27 2018-11-06 Academia Sinica Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
IL249188B2 (en) 2014-05-27 2024-03-01 Academia Sinica Anti-her2 glycoantibodies and uses thereof
KR20170003720A (ko) 2014-05-27 2017-01-09 아카데미아 시니카 항-ｃｄ20 글리코항체 및 이의 용도
KR20170010003A (ko) 2014-05-27 2017-01-25 아카데미아 시니카 박테로이드 기원의 푸코시다제 및 이의 사용 방법
JP7063538B2 (ja) 2014-05-28 2022-05-09 アカデミア シニカ 抗ＴＮＦα糖操作抗体群およびその使用
GB201410226D0 (en) 2014-06-09 2014-07-23 Immunovia Ab Methods and arrays for use in the same
WO2015191613A1 (en) 2014-06-10 2015-12-17 Crescendo Bioscience Biomarkers and methods for measuring and monitoring axial spondyloarthritis disease activity
WO2015191881A2 (en) 2014-06-11 2015-12-17 Green Kathy A Use of vista agonists and antagonists to suppress or enhance humoral immunity
EP3161480B1 (en) 2014-06-25 2020-02-12 Tel HaShomer Medical Research Infrastructure and Services Ltd. Identification of cancer stem cell markers and use of same for diagnosis and treatment
FR3023003B1 (fr) 2014-06-27 2016-07-15 Bio-Rad Innovations Combinaison synergique de biomarqueurs pour la detection et l'evaluation d'une fibrose hepatique
US20170196954A1 (en) 2014-07-15 2017-07-13 Immune Design Corp. Prime-boost regimens with a tlr4 agonist adjuvant and a lentiviral vector
EP3171896A4 (en) 2014-07-23 2018-03-21 Mayo Foundation for Medical Education and Research Targeting dna-pkcs and b7-h1 to treat cancer
CN107531800B (zh) 2014-07-25 2021-08-10 赛拉福柯蒂斯公司 用于嵌合抗原受体分子的调控表达的慢病毒载体
US10422004B2 (en) 2014-08-08 2019-09-24 Children's Hospital Medical Center Diagnostic method for distinguishing forms of esophageal eosinophilia
CN107076746B (zh) 2014-08-14 2020-05-29 米密德诊断学有限公司 使用流形和超平面进行生物学数据的计算机分析
WO2016026978A1 (en) 2014-08-22 2016-02-25 Universite Nice Sophia Antipolis Methods and pharmaceutical compositions for treating drug addiction
WO2016040369A2 (en) 2014-09-08 2016-03-17 Academia Sinica HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
WO2016057683A2 (en) 2014-10-07 2016-04-14 Ann And Robert H. Lurie Children's Hospital Of Chicago Novel anti-nodal antibodies and methods of using same
CN106973568B (zh) 2014-10-08 2021-07-23 诺华股份有限公司 预测针对嵌合抗原受体疗法的治疗应答性的生物标志及其用途
DE102015220401B4 (de) 2014-10-20 2022-12-29 Gen-Probe Incorporated Erythrozyten-Lyselösung
US9107906B1 (en) 2014-10-28 2015-08-18 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
EP3221340B1 (en) 2014-11-19 2024-05-22 P & M Venge AB Diagnostic method employing human neutrophil lipocalin (hnl)
CN107405398A (zh) 2014-12-05 2017-11-28 伊穆奈克斯特股份有限公司 鉴定vsig8作为推定vista受体及其用以产生vista/vsig8激动剂和拮抗剂的用途
CA2968650A1 (en) 2014-12-11 2016-06-16 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
MA41142A (fr) 2014-12-12 2017-10-17 Amgen Inc Anticorps anti-sclérostine et utilisation de ceux-ci pour traiter des affections osseuses en tant qu'élements du protocole de traitement
US10495645B2 (en) 2015-01-16 2019-12-03 Academia Sinica Cancer markers and methods of use thereof
US9975965B2 (en) 2015-01-16 2018-05-22 Academia Sinica Compositions and methods for treatment and detection of cancers
WO2016118191A1 (en) 2015-01-24 2016-07-28 Academia Sinica Novel glycan conjugates and methods of use thereof
WO2016123329A2 (en) 2015-01-28 2016-08-04 Genentech, Inc. Gene expression markers and treatment of multiple sclerosis
CN107249626A (zh) 2015-02-19 2017-10-13 辉瑞大药厂 脑膜炎奈瑟球菌组合物及其方法
AR103852A1 (es) 2015-03-06 2017-06-07 Genentech Inc DsbA Y DsbC ULTRAPURIFICADOS Y SUS MÉTODOS DE PREPARACIÓN Y USO
WO2016149537A1 (en) 2015-03-17 2016-09-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
GB201504432D0 (en) 2015-03-17 2015-04-29 Electrophoretics Ltd Materials and methods for diagnosis and treatment of alzheimers disease
US10435755B2 (en) 2015-03-27 2019-10-08 Exact Sciences Development Company, Llc Detecting esophageal disorders
US11279768B1 (en) 2015-04-03 2022-03-22 Precision Biologics, Inc. Anti-cancer antibodies, combination therapies, and uses thereof
US9758575B2 (en) 2015-04-06 2017-09-12 Yung Shin Pharmaceutical Industrial Co. Ltd. Antibodies which specifically bind to canine vascular endothelial growth factor and uses thereof
WO2016170022A1 (en) 2015-04-21 2016-10-27 Institut Gustave Roussy Therapeutic methods, products and compositions inhibiting znf555
US20180259516A1 (en) 2015-05-04 2018-09-13 Westfälische Wilhelms-Universität Münster Means and methods for diagnosing and treating inflammatory disorders
US10865250B2 (en) 2015-05-04 2020-12-15 Pieris Pharmaceuticals Gmbh Anti-cancer fusion polypeptide
US20180161300A1 (en) 2015-05-11 2018-06-14 Yeda Research And Development Co., Ltd. Citrin inhibitors for the treatment of cancer
MA42137A (fr) 2015-05-22 2021-04-07 Huahui Health Ltd Anticorps vhb anti-pre-s1
GB201509134D0 (en) 2015-05-28 2015-07-15 Electrophoretics Ltd Biomolecules involved in Alzheimer's disease
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
CN107922497B (zh) 2015-06-24 2022-04-12 詹森药业有限公司 抗vista抗体和片段
DK3341725T3 (da) 2015-08-25 2021-09-06 Prothena Biosciences Ltd Fremgangsmåder til detektering af phosphoryleret alpha-synuklein
JP6914919B2 (ja) 2015-08-28 2021-08-04 ジェネンテック， インコーポレイテッド 抗ヒプシン抗体及びその使用
CN116334205A (zh) 2015-09-03 2023-06-27 诺华股份有限公司 预测细胞因子释放综合征的生物标志物
GB201516801D0 (en) 2015-09-22 2015-11-04 Immunovia Ab Method, array and use thereof
CN108137681B (zh) 2015-09-23 2024-06-18 豪夫迈·罗氏有限公司 抗-vegf抗体的优化的变体
WO2017058999A2 (en) 2015-09-29 2017-04-06 Crescendo Bioscience Biomarkers and methods for assessing response to inflammatory disease therapy withdrawal
JP6830105B2 (ja) 2015-09-29 2021-02-17 クレッシェンド バイオサイエンス インコーポレイテッド 乾癬性関節炎の疾患活動性を評価するためのバイオマーカーおよび方法
US20180280474A1 (en) 2015-10-01 2018-10-04 Amgen Inc. Treatment of bile acid disorders
WO2017066645A1 (en) 2015-10-15 2017-04-20 Inbios International, Inc. Multiplexed lateral flow assay systems and methods for their use
JP6750010B2 (ja) 2015-10-30 2020-09-02 ジェネンテック， インコーポレイテッド 抗ＨｔｒＡ１抗体及びその使用方法
WO2017075045A2 (en) 2015-10-30 2017-05-04 Mayo Foundation For Medical Education And Research Antibodies to b7-h1
KR20250073555A (ko) 2015-10-30 2025-05-27 이그잭트 사이언시즈 코포레이션 복합 증폭 검출 분석 및 혈장으로부터 dna의 분리 및 검출 방법
EP3371222A1 (en) 2015-11-03 2018-09-12 GlycoMimetics, Inc. Methods and compositions for the production of monoclonal antibodies, hematopoietic stem cells, and methods of using the same
BR112018008962A8 (pt) 2015-11-03 2019-02-26 Glycomimetics Inc anticorpos para direcionar células tronco cancerígenas e tratar cânceres agressivos
GB201520258D0 (en) 2015-11-17 2015-12-30 Academisch Ziekenhuis Leiden Modulation of ciliogenesis
EP3391048B1 (en) 2015-12-15 2021-07-07 Case Western Reserve University Oral squamous cell carcinoma evaluation using beta defensin
US10821094B2 (en) 2016-01-13 2020-11-03 Children's Hospital Medical Center Compositions and methods for treating allergic inflammatory conditions
EP3410849B1 (en) 2016-02-05 2023-07-05 Institut Pasteur Use of inhibitors of adam12 as adjuvants in tumor therapies
US10899836B2 (en) 2016-02-12 2021-01-26 Janssen Pharmaceutica Nv Method of identifying anti-VISTA antibodies
EP3423488A4 (en) 2016-02-29 2019-11-06 Foundation Medicine, Inc. METHOD FOR THE TREATMENT OF CANCER
AU2017225854B2 (en) 2016-02-29 2020-11-19 Foundation Medicine, Inc. Therapeutic and diagnostic methods for cancer
US10336784B2 (en) 2016-03-08 2019-07-02 Academia Sinica Methods for modular synthesis of N-glycans and arrays thereof
GB201604124D0 (en) 2016-03-10 2016-04-27 Ucb Biopharma Sprl Pharmaceutical formulation
WO2017161357A1 (en) 2016-03-18 2017-09-21 Caris Science, Inc. Oligonucleotide probes and uses thereof
GB201700138D0 (en) 2017-01-05 2017-02-22 Senzagen Ab Analytical methods and arrays for use in the same
AU2017238455B2 (en) 2016-03-23 2023-01-19 Senzagen Ab Analytical methods and arrays for use in the same
WO2017175058A1 (en) 2016-04-07 2017-10-12 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
KR102564248B1 (ko) 2016-04-15 2023-08-09 이뮤넥스트, 인크. 항-인간 vista 항체 및 이의 용도
CA3021343C (en) 2016-04-20 2024-05-28 Crescendo Bioscience Biomarkers and methods for assessing response to inflammatory disease therapy
US11162091B2 (en) 2016-04-27 2021-11-02 Gen-Probe Incorporated Blood cell lysis reagent
GB201608192D0 (en) 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
US11293017B2 (en) 2016-05-25 2022-04-05 Caris Science, Inc. Oligonucleotide probes and uses thereof
GB201609950D0 (en) 2016-06-07 2016-07-20 Immunovia Ab Biomarkers signatures and uses thereof
GB201609951D0 (en) 2016-06-07 2016-07-20 Immunovia Ab Biomarkers signatures and uses thereof
EP3264087B1 (en) 2016-06-27 2020-04-22 Chimera Biotec GmbH Method and device for quantification of target molecules
JP7112966B2 (ja) 2016-06-30 2022-08-04 シーメンス ヘルシニアーズ ネイザランド ビー．ブイ． 複数の細胞を含む体液試料内で分析物を検出するための装置、システム及び方法
EP3482200B1 (en) 2016-07-10 2022-05-04 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
CN109804245B (zh) 2016-07-10 2022-10-25 米密德诊断学有限公司 感染的早期诊断
US11832801B2 (en) 2016-07-11 2023-12-05 Arizona Board Of Regents On Behalf Of Arizona State University Sweat as a biofluid for analysis and disease identification
WO2018029690A1 (en) 2016-08-10 2018-02-15 Memed Diagnostics Ltd. System and method for analysis of biological data
MA45934A (fr) 2016-08-10 2019-06-19 Centre Nat Rech Scient Procédés et réactifs utilisés pour la détection du paludisme à plasmodium falciparum résistant à la pipéraquine
US11701357B2 (en) 2016-08-19 2023-07-18 Beigene Switzerland Gmbh Treatment of B cell cancers using a combination comprising Btk inhibitors
CA3034057A1 (en) 2016-08-22 2018-03-01 CHO Pharma Inc. Antibodies, binding fragments, and methods of use
EP3504243B1 (en) 2016-08-26 2024-07-24 BeiGene Switzerland GmbH Anti-tim-3 antibodies and use thereof
WO2018045162A1 (en) 2016-09-01 2018-03-08 Biogen Ma Inc. Biomarkers predictive of primary progressive multiple sclerosis and uses thereof
EP3510047A1 (en) 2016-09-07 2019-07-17 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Anti-nkp46 antibodies and therapeutic use of same
WO2018075408A1 (en) 2016-10-17 2018-04-26 Alexion Pharmaceuticals, Inc. Methods of treating acute myeloid leukemia (aml) with combinations of anti-cd200 antibodies, cytarabine, and daunorubicin
US11078298B2 (en) 2016-10-28 2021-08-03 Banyan Biomarkers, Inc. Antibodies to ubiquitin C-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) and related methods
US20180128545A1 (en) 2016-11-08 2018-05-10 Berry Metal Company Modular furnace cooling wall
US20200237881A1 (en) 2019-01-30 2020-07-30 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
WO2018102594A1 (en) 2016-12-01 2018-06-07 Alexion Pharmaceuticals, Inc. Methods of treating solid tumors with anti-cd200 antibodies
US10935555B2 (en) 2016-12-22 2021-03-02 Qiagen Sciences, Llc Determining candidate for induction of labor
US10656164B2 (en) 2016-12-22 2020-05-19 Qiagen Sciences, Llc Screening asymptomatic pregnant woman for preterm birth
KR20190104411A (ko) 2017-01-18 2019-09-09 제넨테크, 인크. 항-pd-l1 항체에 대한 이디오타입 항체 및 이의 용도
WO2018136728A1 (en) 2017-01-20 2018-07-26 Children's Hospital Medical Center Methods and compositions relating to oprm1 dna methylation for personalized pain management
KR102667067B1 (ko) 2017-01-27 2024-05-17 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 메틸화된 dna 분석에 의한 결장 신조직형성의 검출
GB201701572D0 (en) 2017-01-31 2017-03-15 Immunovia Ab Methods, arrays and uses thereof
EP3577130A2 (en) 2017-01-31 2019-12-11 Pfizer Inc Neisseria meningitidis compositions and methods thereof
WO2018148180A2 (en) 2017-02-07 2018-08-16 Immune Design Corp. Materials and methods for identifying and treating cancer patients
US12282029B2 (en) 2017-05-08 2025-04-22 MPB Fertility, Inc. Portable diagnostic system for ovulation cycle monitoring
US11061026B2 (en) 2017-02-17 2021-07-13 MFB Fertility, Inc. System of evaluating corpus luteum function by recurrently evaluating progesterone non-serum bodily fluids on multiple days
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
WO2018200505A1 (en) 2017-04-24 2018-11-01 Genentech, Inc. Erbb2/her2 mutations in the transmbrane or juxtamembrane domain
GB201706464D0 (en) 2017-04-24 2017-06-07 Senzagen Ab Analytical methods and arrays for use in the same
WO2018202471A1 (en) 2017-05-02 2018-11-08 Bayer Aktiengesellschaft Tmem16a modulation for diagnostic or therapeutic use in pulmonary hypertension (ph)
JP7146286B2 (ja) 2017-05-10 2022-10-04 ローワン・ユニバーシティ 多発性硬化症の進行を検出する、サブタイプ分類する、および／または評価するための、診断用バイオマーカー
EP4296678A3 (en) 2017-09-14 2024-06-12 Laboratory Corporation of America Holdings Assessing myocardial infarction and serious infection risk in rheumatoid arthritis patients
GB201715445D0 (en) 2017-09-25 2017-11-08 Senzagen Ab Novel cell line and uses thereof
US20200225244A1 (en) 2017-09-26 2020-07-16 Sanford Burnham Prebys Medical Discovery Institute Compositions and methods for assessing painful demyelinating and nondemyelinating diseases
US11761963B2 (en) 2017-09-27 2023-09-19 Alexion Pharmaceuticals, Inc. Biomarker signature for predicting tumor response to anti-CD200 therapy
EP3697809A1 (en) 2017-10-20 2020-08-26 Institut Curie Dap10/12 based cars adapted for rush
AU2018358804A1 (en) 2017-11-02 2020-04-09 Bayer Aktiengesellschaft Bispecific antibodies binding ALK-1 and BMPR-2
CN111587123A (zh) 2017-11-09 2020-08-25 品通治疗有限公司 用于生成和使用人源化构象特异性磷酸化的τ抗体的方法和组合物
JP7731196B2 (ja) 2017-11-14 2025-08-29 中外製薬株式会社 抗Ｃ１ｓ抗体および使用方法
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
WO2019126536A1 (en) 2017-12-20 2019-06-27 Alexion Pharmaceuticals Inc. Humanized anti-cd200 antibodies and uses thereof
US12139533B2 (en) 2017-12-20 2024-11-12 Alexion Pharmaceuticals, Inc. Liquid formulations of anti-CD200 antibodies
WO2019121687A2 (en) 2017-12-21 2019-06-27 Friedrich-Alexander-Universität Erlangen-Nürnberg Immunotoxin conjugates for use in therapy
TWI816729B (zh) 2017-12-30 2023-10-01 英屬開曼群島商百濟神州有限公司 抗tigit抗體及其作為治療和診斷的用途
MX2020006171A (es) 2018-01-12 2020-09-03 Bristol Myers Squibb Co Terapia de combinacion con anticuerpos anti interleucina-8 (il-8) y anticuerpos anti receptor de muerte programada (pd-1) para tratar cancer.
JP7458318B2 (ja) 2018-02-12 2024-03-29 ハダシット メディカル リサーチ サービシーズ アンド ディベロップメント リミテッド 癌治療のためのｓｌａｍｆ６スプライスバリアントの調節
US11859250B1 (en) 2018-02-23 2024-01-02 Children's Hospital Medical Center Methods for treating eosinophilic esophagitis
EP3530282A1 (en) 2018-02-27 2019-08-28 Diaccurate Therapeutic methods
EP3775900A1 (en) 2018-03-26 2021-02-17 Alexion Pharmaceuticals, Inc. High throughput method for measuring the protease activity of complement c3 convertase
SG11202008206TA (en) 2018-03-30 2020-09-29 Amgen Inc C-terminal antibody variants
CN112334485B (zh) 2018-04-06 2024-09-27 百进生物科技公司 抗-四次穿膜蛋白33药剂及其组合物以及制备和使用方法
US12360103B2 (en) 2018-04-20 2025-07-15 Children's Hospital Medical Center Blood biomarker for eosinophilic gastrointestinal disorders
WO2019237119A1 (en) 2018-06-08 2019-12-12 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services New compositions and detection methods for onchocerca volvulus infection
JP2021528476A (ja) 2018-06-28 2021-10-21 サルアクア ダイアグノスティックス， インコーポレイテッド ハプトグロビン関連タンパク質と関係する組成物および方法
WO2020023418A1 (en) 2018-07-23 2020-01-30 Enclear Therapies, Inc. Methods of treating neurological disorders
AU2019310039A1 (en) 2018-07-23 2021-02-18 Enclear Therapies, Inc. Methods of treating neurological disorders
US12181465B2 (en) 2018-08-22 2024-12-31 MFB Fertility, Inc. Method for evaluating urine of a subject to estimate the fertile window by evaluating for the presence of analytes of estrogen and progesterone
WO2020043693A1 (en) 2018-08-29 2020-03-05 Westfälische Wilhelms-Universität Münster Diagnosis of multiple sclerosis
WO2020051277A1 (en) 2018-09-06 2020-03-12 Board Of Regents, The University Of Texas System Treatment and prevention of hemophilic arthropathy with an antibody against endothelial cell protein c receptor (epcr)
JP2022501374A (ja) 2018-09-21 2022-01-06 プレジデント アンド フェローズ オブ ハーバード カレッジ 糖尿病を治療するための方法及び組成物、ならびに分泌タンパク質をコードするｍＲＮＡを濃縮する方法
EP3856343A1 (en) 2018-09-25 2021-08-04 Biolegend, Inc. Anti-tlr9 agents and compositions and methods for making and using the same
DE102018124022A1 (de) 2018-09-28 2020-04-02 Rheinisch-Westfälische Technische Hochschule (Rwth) Aachen Hyaluronsäurestabilisator
US20240269254A1 (en) 2018-10-05 2024-08-15 Bavarian Nordic A/S Combination Therapy for Treating Cancer with an Intravenous Administration of a Recombinant MVA and an Immune Checkpoint Antagonist or Agonist
US11674961B2 (en) 2018-10-12 2023-06-13 Quidel Corporation Extraction reagent for use in an assay for detection of group A Streptococcus
WO2020081493A1 (en) 2018-10-16 2020-04-23 Molecular Templates, Inc. Pd-l1 binding proteins
US12264189B2 (en) 2018-10-31 2025-04-01 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
SG11202104918PA (en) 2018-11-20 2021-06-29 Bavarian Nordic As Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l
CA3121170A1 (en) 2018-11-30 2020-06-04 Caris Mpi, Inc. Next-generation molecular profiling
US12428484B2 (en) 2018-12-06 2025-09-30 Alexion Pharmaceuticals, Inc. Anti-ALK2 antibodies and uses thereof
KR20210111261A (ko) 2019-01-03 2021-09-10 센자겐 아베 호흡기 감작을 유도할 수 있는 작용제의 식별 방법 및 그 방법에 사용하기 위한 어레이 및 분석용 키트
WO2020160322A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Tolerization reduces intolerance to pegloticase and prolongs the urate lowering effect (triple)
CN113365661A (zh) 2019-01-31 2021-09-07 新加坡科技研究局 用于治疗或预防癌症的cnx/erp57抑制剂
EP3693063A1 (en) 2019-02-06 2020-08-12 Diaccurate Methods and compositions for treating cancer
IL264768A (en) 2019-02-10 2020-08-31 Sagi Irit ANTI-MATRIX METALLOPROTEINASE 7 (MMP-7) inhibitory antibody and its use
CN113661175A (zh) 2019-02-15 2021-11-16 整体分子公司 包含共同轻链的抗体及其用途
CN113767113B (zh) 2019-02-15 2025-01-03 因特格尔莫来库乐有限公司 密封蛋白6抗体及其用途
US12297501B2 (en) 2019-02-25 2025-05-13 Children's Hospital Medical Center Methods for diagnosing and treating eosinophilic gastritis
WO2020176637A1 (en) 2019-02-26 2020-09-03 Pantheryx, Inc. Compositions for management of disorders of the gastrointestinal tract
US20220177581A1 (en) 2019-03-11 2022-06-09 Memorial Sloan Kettering Cancer Center Cd22 antibodies and methods of using the same
GB201904472D0 (en) 2019-03-29 2019-05-15 Immunovia Ab Methods, arrays and uses thereof
KR20220011123A (ko) 2019-04-11 2022-01-27 엔클리어 테라피스, 인크. 뇌척수액 개선 방법 및 이를 위한 디바이스 및 시스템
US12337140B2 (en) 2020-09-29 2025-06-24 Enclear Therapies, Inc. Subarachnoid fluid management method and system with varying rates
EP3976646A4 (en) 2019-05-28 2023-04-19 Shanghaitech University COMPOSITION AND METHODS FOR THE TREATMENT OF ECTODERMAL DYSPLASIA 2, CLOUSTON TYPE
EP3990488A4 (en) 2019-06-27 2023-09-13 Ramot at Tel-Aviv University Ltd. SEMAPHORIN 3A ANTIBODIES AND THEIR USES
US12007388B2 (en) 2019-08-22 2024-06-11 The Hong Kong University Of Science And Technology System for single-molecule isolation for cell populations and single cells, and methods and uses thereof
CN115605222A (zh) 2019-09-27 2023-01-13 辉瑞公司（Us） 脑膜炎奈瑟氏菌组合物及其方法
AU2020384953A1 (en) 2019-11-11 2022-06-23 Ibi-Ag Innovative Bio Insecticides Ltd. Insect control nanobodies and uses thereof
WO2021099586A1 (en) 2019-11-20 2021-05-27 Bavarian Nordic A/S Recombinant mva viruses for intratumoral and/or intravenous administration for treating cancer
KR20220130108A (ko) 2019-12-02 2022-09-26 캐리스 엠피아이, 아이엔씨. 범-암 백금 반응 예측기
JP2023507083A (ja) 2019-12-19 2023-02-21 クイデル コーポレーション モノクローナル抗体融合物
EP4090681A1 (en) 2020-01-17 2022-11-23 Biolegend, Inc. Anti-tlr7 agents and compositions and methods for making and using the same
US20230094142A1 (en) 2020-01-29 2023-03-30 Memed Diagnostics Ltd. Methods of diagnosing and classifying viral infections
WO2021188389A2 (en) 2020-03-17 2021-09-23 Genevant Sciences Gmbh Cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
US12326451B2 (en) 2020-04-01 2025-06-10 Institut Pasteur Severe acute respiratory syndrome (SARS)—associated coronavirus diagnostics
US11815513B2 (en) 2020-04-01 2023-11-14 Institut Pasteur Severe acute respiratory syndrome (SARS)-associated coronavirus diagnostics
WO2021209824A1 (en) 2020-04-17 2021-10-21 Institut Pasteur Methods and products for serological analysis of sars-cov-2 infection
AU2021263767A1 (en) 2020-04-30 2022-09-08 Genentech, Inc. KRas specific antibodies and uses thereof
WO2021239666A1 (en) 2020-05-26 2021-12-02 Diaccurate Therapeutic methods
CN115667294A (zh) 2020-06-01 2023-01-31 基因泰克公司 制备细胞外囊泡的方法及细胞外囊泡的用途
TW202216771A (zh) 2020-06-26 2022-05-01 德商拜耳廠股份有限公司 用於治療應用之ccr8抗體
WO2022008976A1 (en) 2020-07-10 2022-01-13 Institut Pasteur Use of gdf11 to diagnose and treat anxiety and depression
GB202010970D0 (en) 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
US20240053339A1 (en) 2020-09-21 2024-02-15 Theravectys High throughput methods and products for sars-cov-2 sero-neutralization assay
WO2022093641A1 (en) 2020-10-30 2022-05-05 BioLegend, Inc. Anti-nkg2a agents and compositions and methods for making and using the same
WO2022093640A1 (en) 2020-10-30 2022-05-05 BioLegend, Inc. Anti-nkg2c agents and compositions and methods for making and using the same
EP4262883B1 (en) 2020-12-18 2025-05-28 Genevant Sciences Gmbh Peg lipids and lipid nanoparticles
WO2022157094A2 (en) 2021-01-22 2022-07-28 Bayer Aktiengesellschaft Lrrc15 antibodies and conjugates thereof
EP4046652A1 (en) 2021-02-23 2022-08-24 Johann Wolfgang Goethe-Universität Frankfurt Compositions and methods for diagnosing, treating and preventing carrion's disease
US20240317847A1 (en) 2021-02-26 2024-09-26 Bayer Aktiengesellschaft INHIBITORS OF IL-11 OR IL-11Ra FOR USE IN THE TREATMENT OF ABNORMAL UTERINE BLEEDING
GB202104422D0 (en) 2021-03-29 2021-05-12 Orre Lukas Methods
US20240183855A1 (en) 2021-03-30 2024-06-06 Westfaelische Wilhelms-Universitaet Muenster Classification of neurological or psychiatric disease manifestations using multi-dimensional cerebrospinal fluid analysis
EP4070814A1 (en) 2021-04-07 2022-10-12 Lama France Sars-cov-2 polypeptides and uses thereof
AR125344A1 (es) 2021-04-15 2023-07-05 Chugai Pharmaceutical Co Ltd Anticuerpo anti-c1s
WO2023118508A1 (en) 2021-12-23 2023-06-29 Bavarian Nordic A/S Recombinant mva viruses for intraperitoneal administration for treating cancer
AU2023214198A1 (en) 2022-01-31 2024-08-15 Genevant Sciences Gmbh Ionizable cationic lipids for lipid nanoparticles
WO2023192478A1 (en) 2022-04-01 2023-10-05 Bristol-Myers Squibb Company Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
CN119585444A (zh) 2022-05-18 2025-03-07 巴斯德研究所 人圆环病毒的鉴定
EP4558523A1 (en) 2022-07-19 2025-05-28 Biolegend, Inc. Anti-cd157 antibodies, antigen-binding fragments thereof and compositions and methods for making and using the same
EP4572854A2 (en) 2022-08-18 2025-06-25 Biolegend, Inc. Anti-axl antibodies, antigen-binding fragments thereof and methods for making and using the same
WO2024044675A1 (en) 2022-08-25 2024-02-29 Beigene, Ltd. Methods of cancer treatment using anti-pd1 antibodies in combination with anti-tim3 antibodies
CA3266915A1 (en) 2022-09-09 2024-03-14 Bayer Ag MEDICAL USE OF ANTI-CCR8 ANTIBODIES AND DOSING PROGRAM
WO2024052922A1 (en) 2022-09-11 2024-03-14 Yeda Research And Development Co. Ltd. Anti-klk4 antibodies and uses thereof
KR20250111207A (ko) 2022-11-24 2025-07-22 비원 메디슨즈 아이 게엠베하 항체 약물 접합체
TW202430574A (zh) 2022-11-30 2024-08-01 美商積分分子股份有限公司 針對密連蛋白６之抗體，包括其雙特異性格式
EP4379375A1 (en) 2022-12-01 2024-06-05 Universität Münster Classification of connective tissue disease with neurological manifestation using multi-dimensional peripheral blood analysis
WO2024149703A1 (en) 2023-01-09 2024-07-18 Inserm (Institut National De La Sante Et De La Recherche Medicale) Diagnosis of alzheimer disease
TW202430570A (zh) 2023-01-19 2024-08-01 英屬開曼群島商百濟神州有限公司 抗cmet抗體及使用方法
WO2024165468A1 (en) 2023-02-06 2024-08-15 Bayer Aktiengesellschaft Combination of ccr8 antibodies with dgk inhibitors in the treatment of cancer
CN120813603A (zh) 2023-03-03 2025-10-17 广州百济神州生物制药有限公司 Cd16a抗体和使用方法
AU2024231640A1 (en) 2023-03-03 2025-10-16 Beone Medicines I Gmbh Muc1 and cd16a antibodies and methods of use
WO2024183637A1 (en) 2023-03-03 2024-09-12 Beigene Switzerland Gmbh Muc1 antibodies and methods of use
TW202436354A (zh) 2023-03-06 2024-09-16 瑞士商百濟神州瑞士有限責任公司 抗cldn6抗體以及其使用方法
WO2024184811A1 (en) 2023-03-06 2024-09-12 Beigene Switzerland Gmbh Anti-cd3 multispecific antibodies and methods of use
TW202436353A (zh) 2023-03-06 2024-09-16 瑞士商百濟神州瑞士有限責任公司 抗ｃｌｄｎ６與抗ｃｄ３多重特異性抗體以及使用方法
WO2024200655A1 (en) 2023-03-28 2024-10-03 Westfälische Wilhelms-Universität Münster Predictive level of pd-l1 on microvesicles in the evaluation whether being a responder to a treatment of nsclc
WO2024243217A1 (en) 2023-05-25 2024-11-28 BioLegend, Inc. Ceacam6 binding antibodies and antigen-binding fragments thereof
GB2630774A (en) 2023-06-07 2024-12-11 Curenetics Ltd Lung cancer biomarkers
WO2024261762A2 (en) 2023-06-21 2024-12-26 Metasight Diagnostics Ltd Liver fibrosis, nash and "at-risk" nash biomarkers and methods
WO2025008404A1 (en) 2023-07-04 2025-01-09 Universitaet Regensburg In Vertretung Des Freistaates Bayern Use of soluble cd46 concentration from peripheral blood as a parameter for the diagnosis of non-alcoholic fatty liver disease
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers
WO2025052278A1 (en) 2023-09-05 2025-03-13 Genevant Sciences Gmbh Pyrrolidine based cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
EP4527851A1 (en) 2023-09-22 2025-03-26 Bayer Aktiengesellschaft Bispecific antibodies binding ltbr and lrrc15
WO2025072313A1 (en) 2023-09-27 2025-04-03 BioLegend, Inc. Anti-gpc4 antibodies
TW202515903A (zh) 2023-10-12 2025-04-16 瑞士商百濟神州瑞士有限責任公司 手術前後基於抗ｐｄ－１之治療
GB202316762D0 (en) 2023-11-01 2023-12-13 Rna Guardian Ltd Determination of cancer status
WO2025133951A1 (en) 2023-12-21 2025-06-26 Genevant Sciences Gmbh Ionizable lipids suitable for lipid nanoparticles
WO2025146131A1 (en) 2024-01-05 2025-07-10 Beigene, Ltd. ANTI-FGFR2b ANTIBODIES, CONJUGATES AND METHODS OF USE
WO2025154056A1 (en) 2024-01-21 2025-07-24 Ibi-Ag Innovative Bio Insecticides Ltd. Anti-insect cda nanobodies and uses thereof
WO2025154058A1 (en) 2024-01-21 2025-07-24 Ibi-Ag Innovative Bio Insecticides Ltd. Anti-insect hsp70 nanobodies and uses thereof
WO2025186043A1 (en) 2024-03-06 2025-09-12 Bayer Aktiengesellschaft Pharmaceutical formulation for anti-ccr8 antibodies
WO2025210195A1 (en) 2024-04-03 2025-10-09 Institut Pasteur Apsab combines a nuclease/helicase protein and an argonaute-like protein to cleave dna
WO2025233675A1 (en) 2024-05-10 2025-11-13 Institut Pasteur Use of talosaminidase to regulate populations of archaeal methanogens in industrial, agricultural and medical settings

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) * 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
US3867517A (en) * 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
US4016043A (en) * 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
JPS5347518A (en) * 1976-10-07 1978-04-28 Mochida Pharm Co Ltd Immunologically measuring method
US4098876A (en) * 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
NL185309C (nl) * 1980-07-28 1990-03-01 Akzo Nv Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474892A (en) * 1983-02-16 1984-10-02 Board Of Trustees Of The Leland Stanford Junior University Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same

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