SI2342226T1 - Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe - Google Patents

Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe

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Publication number
SI2342226T1
SI2342226T1 SI200931522A SI200931522A SI2342226T1 SI 2342226 T1 SI2342226 T1 SI 2342226T1 SI 200931522 A SI200931522 A SI 200931522A SI 200931522 A SI200931522 A SI 200931522A SI 2342226 T1 SI2342226 T1 SI 2342226T1
Authority
SI
Slovenia
Prior art keywords
antibodies
human anti
human
Prior art date
Application number
SI200931522A
Other languages
English (en)
Slovenian (sl)
Inventor
Gordon J. Freeman
Rafi Ahmed
Timothy D. Jones
Francis J. Carr
James P. Gregson
Original Assignee
Dana-Farber Cancer Institute Inc.
Emory University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana-Farber Cancer Institute Inc., Emory University filed Critical Dana-Farber Cancer Institute Inc.
Publication of SI2342226T1 publication Critical patent/SI2342226T1/sl

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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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  • General Health & Medical Sciences (AREA)
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  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
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  • Hematology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
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SI200931522A 2008-09-26 2009-09-25 Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe SI2342226T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10053408P 2008-09-26 2008-09-26
PCT/US2009/058475 WO2010036959A2 (en) 2008-09-26 2009-09-25 Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses therefor
EP09816950.1A EP2342226B1 (en) 2008-09-26 2009-09-25 Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
SI2342226T1 true SI2342226T1 (sl) 2016-11-30

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SI200931522A SI2342226T1 (sl) 2008-09-26 2009-09-25 Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe

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US (5) US8552154B2 (enExample)
EP (3) EP3133086B1 (enExample)
JP (4) JP6087503B2 (enExample)
KR (4) KR101814408B1 (enExample)
CN (2) CN108484767B (enExample)
AU (4) AU2009296392B2 (enExample)
BR (1) BRPI0919377A2 (enExample)
CA (2) CA2998281C (enExample)
DK (1) DK2342226T3 (enExample)
ES (2) ES2982109T3 (enExample)
HU (1) HUE030807T2 (enExample)
IL (3) IL211830A (enExample)
MX (2) MX2011003195A (enExample)
PL (1) PL2342226T3 (enExample)
SI (1) SI2342226T1 (enExample)
WO (1) WO2010036959A2 (enExample)

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EP2262837A4 (en) * 2008-03-12 2011-04-06 Merck Sharp & Dohme PD-1 BINDING PROTEINS
WO2009137807A2 (en) 2008-05-08 2009-11-12 Asuragen, Inc. Compositions and methods related to mirna modulation of neovascularization or angiogenesis
US20110129499A1 (en) 2008-05-19 2011-06-02 Paulo Maciag Dual delivery system for heterologous antigens
US9650639B2 (en) 2008-05-19 2017-05-16 Advaxis, Inc. Dual delivery system for heterologous antigens
US9017660B2 (en) 2009-11-11 2015-04-28 Advaxis, Inc. Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors
US8552154B2 (en) 2008-09-26 2013-10-08 Emory University Anti-PD-L1 antibodies and uses therefor
CN102369008B (zh) 2009-03-30 2014-10-29 卫材R&D管理有限公司 脂质体组合物
EP2445932B1 (en) 2009-06-26 2018-02-28 Soricimed Biopharma Inc. Soricidin derived peptides and methods for the detection of trpv-6 cancers and drug delivery
US10016617B2 (en) 2009-11-11 2018-07-10 The Trustees Of The University Of Pennsylvania Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers
TW201134488A (en) * 2010-03-11 2011-10-16 Ucb Pharma Sa PD-1 antibodies
EP2545078A1 (en) 2010-03-11 2013-01-16 UCB Pharma, S.A. Pd-1 antibody
WO2012138377A2 (en) 2010-10-01 2012-10-11 Trustees Of The University Of Pennsylvania The use of listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals
EP2625292B1 (en) 2010-10-07 2018-12-05 The General Hospital Corporation Biomarkers of cancer
CA2829960A1 (en) 2011-03-11 2012-09-20 John Rothman Listeria-based adjuvants
JP6072771B2 (ja) * 2011-04-20 2017-02-01 メディミューン，エルエルシー Ｂ７−ｈ１およびｐｄ−１に結合する抗体およびその他の分子
CA2834548C (en) 2011-04-28 2021-06-01 The Broad Institute, Inc. Inhibitors of histone deacetylase
CN102298053B (zh) * 2011-05-20 2014-01-29 中山大学肿瘤防治中心 原发性肝细胞肝癌术后复发风险评估的组合抗体试剂盒
EP2723380B1 (en) 2011-06-24 2019-08-21 Stephen D. Gillies Light chain immunoglobulin fusion proteins and methods of use thereof
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