JP6087503B2 - ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 - Google Patents
ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 Download PDFInfo
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- JP6087503B2 JP6087503B2 JP2011529280A JP2011529280A JP6087503B2 JP 6087503 B2 JP6087503 B2 JP 6087503B2 JP 2011529280 A JP2011529280 A JP 2011529280A JP 2011529280 A JP2011529280 A JP 2011529280A JP 6087503 B2 JP6087503 B2 JP 6087503B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10053408P | 2008-09-26 | 2008-09-26 | |
| US61/100,534 | 2008-09-26 | ||
| PCT/US2009/058475 WO2010036959A2 (en) | 2008-09-26 | 2009-09-25 | Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses therefor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015107525A Division JP6663653B2 (ja) | 2008-09-26 | 2015-05-27 | ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012503984A JP2012503984A (ja) | 2012-02-16 |
| JP2012503984A5 JP2012503984A5 (enExample) | 2012-11-15 |
| JP6087503B2 true JP6087503B2 (ja) | 2017-03-08 |
Family
ID=42060416
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011529280A Expired - Fee Related JP6087503B2 (ja) | 2008-09-26 | 2009-09-25 | ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 |
| JP2015107525A Active JP6663653B2 (ja) | 2008-09-26 | 2015-05-27 | ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 |
| JP2018031722A Active JP6723273B2 (ja) | 2008-09-26 | 2018-02-26 | ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 |
| JP2020021417A Pending JP2020108376A (ja) | 2008-09-26 | 2020-02-12 | ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015107525A Active JP6663653B2 (ja) | 2008-09-26 | 2015-05-27 | ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 |
| JP2018031722A Active JP6723273B2 (ja) | 2008-09-26 | 2018-02-26 | ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 |
| JP2020021417A Pending JP2020108376A (ja) | 2008-09-26 | 2020-02-12 | ヒト抗pd−1、pd−l1、及びpd−l2抗体とその用途 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US8552154B2 (enExample) |
| EP (3) | EP3133086B1 (enExample) |
| JP (4) | JP6087503B2 (enExample) |
| KR (4) | KR101924874B1 (enExample) |
| CN (2) | CN108484767B (enExample) |
| AU (4) | AU2009296392B2 (enExample) |
| BR (1) | BRPI0919377A2 (enExample) |
| CA (2) | CA2998281C (enExample) |
| DK (1) | DK2342226T3 (enExample) |
| ES (2) | ES2592216T3 (enExample) |
| HU (1) | HUE030807T2 (enExample) |
| IL (3) | IL211830A (enExample) |
| MX (2) | MX2011003195A (enExample) |
| PL (1) | PL2342226T3 (enExample) |
| SI (1) | SI2342226T1 (enExample) |
| WO (1) | WO2010036959A2 (enExample) |
Families Citing this family (859)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ600758A (en) | 2007-06-18 | 2013-09-27 | Merck Sharp & Dohme | Antibodies to human programmed death receptor pd-1 |
| EP2262837A4 (en) * | 2008-03-12 | 2011-04-06 | Merck Sharp & Dohme | PD-1 BINDING PROTEINS |
| EP2285960B1 (en) | 2008-05-08 | 2015-07-08 | Asuragen, INC. | Compositions and methods related to mir-184 modulation of neovascularization or angiogenesis |
| ES2741730T3 (es) | 2008-05-19 | 2020-02-12 | Advaxis Inc | Sistema de administración doble para antígenos heterólogos que comprende una cepa de Listeria recombinante atenuada por la mutación de dal/dat y la deleción de ActA que comprende una molécula de ácido nucleico que codifica una proteína de fusión de listeriolisina O - antígeno prostático específico |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| ES2592216T3 (es) | 2008-09-26 | 2016-11-28 | Dana-Farber Cancer Institute, Inc. | Anticuerpos anti-PD-1, PD-L1 y PD-L2 humanos y sus usos |
| KR101495951B1 (ko) | 2009-03-30 | 2015-02-25 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 리포솜 조성물 |
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