KR102197527B1 - 인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 - Google Patents
인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 Download PDFInfo
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- KR102197527B1 KR102197527B1 KR1020197026614A KR20197026614A KR102197527B1 KR 102197527 B1 KR102197527 B1 KR 102197527B1 KR 1020197026614 A KR1020197026614 A KR 1020197026614A KR 20197026614 A KR20197026614 A KR 20197026614A KR 102197527 B1 KR102197527 B1 KR 102197527B1
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10053408P | 2008-09-26 | 2008-09-26 | |
| US61/100,534 | 2008-09-26 | ||
| PCT/US2009/058475 WO2010036959A2 (en) | 2008-09-26 | 2009-09-25 | Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses therefor |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187034308A Division KR102097887B1 (ko) | 2008-09-26 | 2009-09-25 | 인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20190107756A KR20190107756A (ko) | 2019-09-20 |
| KR102197527B1 true KR102197527B1 (ko) | 2020-12-31 |
Family
ID=42060416
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197026614A Active KR102197527B1 (ko) | 2008-09-26 | 2009-09-25 | 인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 |
| KR1020117009345A Active KR101814408B1 (ko) | 2008-09-26 | 2009-09-25 | 인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 |
| KR1020177037176A Active KR101924874B1 (ko) | 2008-09-26 | 2009-09-25 | 인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 |
| KR1020187034308A Active KR102097887B1 (ko) | 2008-09-26 | 2009-09-25 | 인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020117009345A Active KR101814408B1 (ko) | 2008-09-26 | 2009-09-25 | 인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 |
| KR1020177037176A Active KR101924874B1 (ko) | 2008-09-26 | 2009-09-25 | 인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 |
| KR1020187034308A Active KR102097887B1 (ko) | 2008-09-26 | 2009-09-25 | 인간 항-pd-1, pd-l1, 및 pd-l2 항체 및 그의 용도 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US8552154B2 (enExample) |
| EP (3) | EP3133086B1 (enExample) |
| JP (4) | JP6087503B2 (enExample) |
| KR (4) | KR102197527B1 (enExample) |
| CN (2) | CN102264762B (enExample) |
| AU (4) | AU2009296392B2 (enExample) |
| BR (1) | BRPI0919377A2 (enExample) |
| CA (2) | CA2738252C (enExample) |
| DK (1) | DK2342226T3 (enExample) |
| ES (2) | ES2592216T3 (enExample) |
| HU (1) | HUE030807T2 (enExample) |
| IL (3) | IL211830A (enExample) |
| MX (2) | MX349463B (enExample) |
| PL (1) | PL2342226T3 (enExample) |
| SI (1) | SI2342226T1 (enExample) |
| WO (1) | WO2010036959A2 (enExample) |
Families Citing this family (881)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101586617B1 (ko) | 2007-06-18 | 2016-01-20 | 머크 샤프 앤 도메 비.브이. | 사람 프로그램된 사멸 수용체 pd-1에 대한 항체 |
| US8168757B2 (en) * | 2008-03-12 | 2012-05-01 | Merck Sharp & Dohme Corp. | PD-1 binding proteins |
| US8258111B2 (en) | 2008-05-08 | 2012-09-04 | The Johns Hopkins University | Compositions and methods related to miRNA modulation of neovascularization or angiogenesis |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| EP2853269B1 (en) | 2008-05-19 | 2019-05-01 | Advaxis, Inc. | Dual delivery system for heterologous antigens comprising a recombinant Listeria strain attenuated by mutation of dal/dat and deletion of ActA comprising a nucleic acid molecule encoding an listeriolysin O - prostate specific anigen fusion protein |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004056875A1 (en) | 2002-12-23 | 2004-07-08 | Wyeth | Antibodies against pd-1 and uses therefor |
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