JP2012500855A - Ｐｄ−１アンタゴニストおよび感染性疾患を処置するための方法 - Google Patents

Ｐｄ−１アンタゴニストおよび感染性疾患を処置するための方法 Download PDF

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JP2012500855A
JP2012500855A JP2011525158A JP2011525158A JP2012500855A JP 2012500855 A JP2012500855 A JP 2012500855A JP 2011525158 A JP2011525158 A JP 2011525158A JP 2011525158 A JP2011525158 A JP 2011525158A JP 2012500855 A JP2012500855 A JP 2012500855A
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antagonist
cell
polypeptide
virus
cells
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JP2012500855A5 (OSRAM
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ソロモン、ランガーマン
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Amplimmune Inc
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Amplimmune Inc
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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JP2011525158A 2008-08-25 2009-08-25 Ｐｄ−１アンタゴニストおよび感染性疾患を処置するための方法 Pending JP2012500855A (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US9170508P 2008-08-25 2008-08-25
US9150208P 2008-08-25 2008-08-25
US9169408P 2008-08-25 2008-08-25
US9170908P 2008-08-25 2008-08-25
US61/091,502 2008-08-25
US61/091,694 2008-08-25
US61/091,705 2008-08-25
US61/091,709 2008-08-25
US14254809P 2009-01-05 2009-01-05
US61/142,548 2009-01-05
US16565209P 2009-04-01 2009-04-01
US61/165,652 2009-04-01
PCT/US2009/054970 WO2010098788A2 (en) 2008-08-25 2009-08-25 Pd-i antagonists and methods for treating infectious disease

Publications (2)

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JP2012500855A true JP2012500855A (ja) 2012-01-12
JP2012500855A5 JP2012500855A5 (OSRAM) 2012-10-11

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JP2011525159A Pending JP2012510429A (ja) 2008-08-25 2009-08-25 Ｐｄ−１アンタゴニストおよびその使用方法
JP2011525158A Pending JP2012500855A (ja) 2008-08-25 2009-08-25 Ｐｄ−１アンタゴニストおよび感染性疾患を処置するための方法
JP2011525157A Withdrawn JP2012500652A (ja) 2008-08-25 2009-08-25 標的化共刺激ポリペプチドおよび癌を処置するための使用方法
JP2015040548A Pending JP2015129172A (ja) 2008-08-25 2015-03-02 Ｐｄ−１アンタゴニストおよびその使用方法

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JP2011525157A Withdrawn JP2012500652A (ja) 2008-08-25 2009-08-25 標的化共刺激ポリペプチドおよび癌を処置するための使用方法
JP2015040548A Pending JP2015129172A (ja) 2008-08-25 2015-03-02 Ｐｄ−１アンタゴニストおよびその使用方法

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US (4) US20110223188A1 (OSRAM)
EP (4) EP2328919A2 (OSRAM)
JP (4) JP2012510429A (OSRAM)
KR (1) KR20110074850A (OSRAM)
CN (2) CN102203125A (OSRAM)
AU (1) AU2009288289B2 (OSRAM)
BR (1) BRPI0917891A2 (OSRAM)
CA (1) CA2735006A1 (OSRAM)
EA (1) EA201170375A1 (OSRAM)
IL (1) IL211299A (OSRAM)
MX (1) MX2011002250A (OSRAM)
WO (3) WO2010027828A2 (OSRAM)
ZA (1) ZA201101119B (OSRAM)

Cited By (3)

* Cited by examiner, † Cited by third party
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JP2012510429A (ja) * 2008-08-25 2012-05-10 アンプリミューン、インコーポレーテッド Ｐｄ−１アンタゴニストおよびその使用方法
JP2017525354A (ja) * 2014-08-08 2017-09-07 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 高親和性ｐｄ−１薬剤とその使用方法
JP2020534352A (ja) * 2017-09-07 2020-11-26 キュー バイオファーマ，インコーポレーテッド コンジュゲーション部位を有するｔ細胞調節多量体ポリペプチド及びその使用方法

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HRP20170908T1 (hr) 2008-12-09 2017-09-22 F. Hoffmann - La Roche Ag Protutijela anti-pd-l1 i njihova uporaba za poboljšanje funkcije t-stanice
EP3269799A1 (en) 2009-03-04 2018-01-17 The Trustees of the University of Pennsylvania Compositions comprising angiogenic factors and uses thereof
RU2568066C2 (ru) 2009-03-25 2015-11-10 Дженентек, Инк. Антитела против fgfr3 и способы их применения
MY160203A (en) 2009-03-30 2017-02-28 Eisai R&D Man Co Ltd Liposome composition
US9724404B2 (en) 2009-04-13 2017-08-08 INSERM (Institut National de la Santé et de la Recherche Médicale) HPV particles and uses thereof
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JP2013512251A (ja) * 2009-11-24 2013-04-11 アンプリミューン、インコーポレーテッド Ｐｄ−ｌ１／ｐｄ−ｌ２の同時阻害
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MX386545B (es) 2010-05-05 2025-03-19 Univ New York Leucocidinas de staphylococcus aureus, composiciones terapéuticas y usos de las mismas.
JP5981436B2 (ja) 2010-10-01 2016-08-31 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 寄生的に感染している対象におけるワクチン不応答性を反転させるためのリステリアワクチンベクターの使用
WO2012062218A1 (en) 2010-11-11 2012-05-18 The University Of Hong Kong Soluble pd-1 variants, fusion constructs, and uses thereof
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
WO2012113413A1 (en) * 2011-02-21 2012-08-30 Curevac Gmbh Vaccine composition comprising complexed immunostimulatory nucleic acids and antigens packaged with disulfide-linked polyethyleneglycol/peptide conjugates
WO2012125551A1 (en) 2011-03-11 2012-09-20 Advaxis Listeria-based adjuvants
US9675561B2 (en) 2011-04-28 2017-06-13 President And Fellows Of Harvard College Injectable cryogel vaccine devices and methods of use thereof
CA2840409A1 (en) 2011-06-28 2013-01-03 Whitehead Institute For Biomedical Research Using sortases to install click chemistry handles for protein ligation
JP6105578B2 (ja) 2011-07-21 2017-03-29 トレロ ファーマシューティカルズ， インコーポレイテッド 複素環式プロテインキナーゼ阻害剤
AU2012290121B2 (en) 2011-08-01 2015-11-26 Genentech, Inc. Methods of treating cancer using PD-1 axis binding antagonists and MEK inhibitors
JP6259763B2 (ja) * 2011-10-17 2018-01-10 ヘルレフ ホスピタルＨｅｒｌｅｖ Ｈｏｓｐｉｔａｌ Ｐｄ−ｌ１に基づく免疫療法
HK1205944A1 (en) 2012-03-12 2015-12-31 阿德瓦希斯公司 Suppressor cell function inhibition following listeria vaccine treatment
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
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US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
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JP2012510429A (ja) 2012-05-10
CN102203125A (zh) 2011-09-28
JP2015129172A (ja) 2015-07-16
US20110195068A1 (en) 2011-08-11
CN104740610A (zh) 2015-07-01

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