IL117701A - Long-lasting contact lenses - Google Patents
Long-lasting contact lensesInfo
- Publication number
- IL117701A IL117701A IL11770196A IL11770196A IL117701A IL 117701 A IL117701 A IL 117701A IL 11770196 A IL11770196 A IL 11770196A IL 11770196 A IL11770196 A IL 11770196A IL 117701 A IL117701 A IL 117701A
- Authority
- IL
- Israel
- Prior art keywords
- lens
- opthalmic
- weight percent
- wear
- extended
- Prior art date
Links
- 239000000463 material Substances 0.000 claims abstract description 230
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 151
- 239000001301 oxygen Substances 0.000 claims abstract description 151
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 151
- 230000035699 permeability Effects 0.000 claims abstract description 121
- 230000010220 ion permeability Effects 0.000 claims abstract description 100
- 239000012530 fluid Substances 0.000 claims abstract description 31
- 230000036541 health Effects 0.000 claims abstract description 27
- 239000000203 mixture Substances 0.000 claims description 232
- 238000000034 method Methods 0.000 claims description 189
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 170
- 229910001868 water Inorganic materials 0.000 claims description 166
- -1 polysiloxane Polymers 0.000 claims description 161
- 229920000642 polymer Polymers 0.000 claims description 107
- 125000004432 carbon atom Chemical group C* 0.000 claims description 82
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- 239000000178 monomer Substances 0.000 claims description 62
- 238000006116 polymerization reaction Methods 0.000 claims description 60
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 57
- 229920001296 polysiloxane Polymers 0.000 claims description 53
- 238000012360 testing method Methods 0.000 claims description 47
- 125000000217 alkyl group Chemical group 0.000 claims description 46
- 150000002500 ions Chemical class 0.000 claims description 46
- 238000006243 chemical reaction Methods 0.000 claims description 44
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 claims description 38
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 35
- 230000008961 swelling Effects 0.000 claims description 34
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- 239000002904 solvent Substances 0.000 claims description 30
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- 239000011162 core material Substances 0.000 claims description 28
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 claims description 27
- 229910052757 nitrogen Inorganic materials 0.000 claims description 27
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- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical group CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 25
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 23
- 239000007789 gas Substances 0.000 claims description 22
- RBQRWNWVPQDTJJ-UHFFFAOYSA-N methacryloyloxyethyl isocyanate Chemical compound CC(=C)C(=O)OCCN=C=O RBQRWNWVPQDTJJ-UHFFFAOYSA-N 0.000 claims description 21
- 229910052786 argon Inorganic materials 0.000 claims description 19
- NIMLQBUJDJZYEJ-UHFFFAOYSA-N isophorone diisocyanate Chemical compound CC1(C)CC(N=C=O)CC(C)(CN=C=O)C1 NIMLQBUJDJZYEJ-UHFFFAOYSA-N 0.000 claims description 19
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- BESKSSIEODQWBP-UHFFFAOYSA-N 3-tris(trimethylsilyloxy)silylpropyl 2-methylprop-2-enoate Chemical group CC(=C)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C BESKSSIEODQWBP-UHFFFAOYSA-N 0.000 claims description 17
- 239000003054 catalyst Substances 0.000 claims description 17
- 150000003077 polyols Chemical class 0.000 claims description 17
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- DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical group FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 claims description 15
- 230000005540 biological transmission Effects 0.000 claims description 13
- 238000000576 coating method Methods 0.000 claims description 11
- 125000005442 diisocyanate group Chemical group 0.000 claims description 11
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 11
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 10
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims description 10
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- 125000002993 cycloalkylene group Chemical group 0.000 claims description 6
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- 239000000243 solution Substances 0.000 description 71
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- 239000000523 sample Substances 0.000 description 19
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95810221 | 1995-04-04 | ||
| CH149695 | 1995-05-19 | ||
| US08569816 US5760100B1 (en) | 1994-09-06 | 1995-12-08 | Extended wear ophthalmic lens |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL117701A0 IL117701A0 (en) | 1996-07-23 |
| IL117701A true IL117701A (en) | 2001-06-14 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11770196A IL117701A (en) | 1995-04-04 | 1996-03-28 | Long-lasting contact lenses |
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| US (6) | US5760100B1 (de) |
| EP (5) | EP1043605B1 (de) |
| JP (4) | JP4216332B2 (de) |
| KR (1) | KR100423467B1 (de) |
| CN (1) | CN1192251C (de) |
| AT (2) | ATE205606T1 (de) |
| AU (4) | AU704749C (de) |
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| HR (1) | HRP960144B1 (de) |
| HU (1) | HU223493B1 (de) |
| IL (1) | IL117701A (de) |
| MX (1) | MX9707553A (de) |
| MY (1) | MY114914A (de) |
| NO (2) | NO327093B1 (de) |
| NZ (1) | NZ304321A (de) |
| PE (1) | PE36797A1 (de) |
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| SI (1) | SI1043605T1 (de) |
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| TW (1) | TW464660B (de) |
| WO (1) | WO1996031792A1 (de) |
| ZA (1) | ZA962656B (de) |
Families Citing this family (729)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5034461A (en) | 1989-06-07 | 1991-07-23 | Bausch & Lomb Incorporated | Novel prepolymers useful in biomedical devices |
| US5760261A (en) * | 1990-02-28 | 1998-06-02 | Guttag; Alvin | Higher fatty acid derivatives of salicylic acid and salts thereof |
| US5760100B1 (en) | 1994-09-06 | 2000-11-14 | Ciba Vision Corp | Extended wear ophthalmic lens |
| US7468398B2 (en) * | 1994-09-06 | 2008-12-23 | Ciba Vision Corporation | Extended wear ophthalmic lens |
| US5923397A (en) * | 1996-03-25 | 1999-07-13 | Bausch & Lomb Incorporated | Bimodulus contact lens article |
| NZ332034A (en) * | 1996-03-27 | 2000-02-28 | Commw Scient Ind Res Org | Process for manufacture of a porous polymer and its use as an ophthalmic device or lens |
| JP3715021B2 (ja) * | 1996-04-09 | 2005-11-09 | Jsr株式会社 | 液状硬化性樹脂組成物 |
| US5807944A (en) * | 1996-06-27 | 1998-09-15 | Ciba Vision Corporation | Amphiphilic, segmented copolymer of controlled morphology and ophthalmic devices including contact lenses made therefrom |
| TW369617B (en) * | 1996-12-06 | 1999-09-11 | Toray Industries | Plastic articles for medical use |
| JPH10231341A (ja) * | 1997-02-20 | 1998-09-02 | Jsr Corp | 液状硬化性樹脂組成物 |
| PE65999A1 (es) * | 1997-09-02 | 1999-07-27 | Novartis Ag | Proceso para la fabricacion de un articulo moldeado |
| AU9743298A (en) * | 1997-09-16 | 1999-04-05 | Novartis Ag | Crosslinkable polyurea polymers |
| US6020445A (en) * | 1997-10-09 | 2000-02-01 | Johnson & Johnson Vision Products, Inc. | Silicone hydrogel polymers |
| US6451871B1 (en) | 1998-11-25 | 2002-09-17 | Novartis Ag | Methods of modifying surface characteristics |
| JPH11228643A (ja) | 1998-02-17 | 1999-08-24 | Menicon Co Ltd | 眼用レンズ材料およびその製法 |
| US6849671B2 (en) | 1998-03-02 | 2005-02-01 | Johnson & Johnson Vision Care, Inc. | Contact lenses |
| US5998498A (en) * | 1998-03-02 | 1999-12-07 | Johnson & Johnson Vision Products, Inc. | Soft contact lenses |
| US6822016B2 (en) * | 2001-09-10 | 2004-11-23 | Johnson & Johnson Vision Care, Inc. | Biomedical devices containing internal wetting agents |
| US7052131B2 (en) | 2001-09-10 | 2006-05-30 | J&J Vision Care, Inc. | Biomedical devices containing internal wetting agents |
| US6367929B1 (en) | 1998-03-02 | 2002-04-09 | Johnson & Johnson Vision Care, Inc. | Hydrogel with internal wetting agent |
| US7461937B2 (en) * | 2001-09-10 | 2008-12-09 | Johnson & Johnson Vision Care, Inc. | Soft contact lenses displaying superior on-eye comfort |
| US6943203B2 (en) | 1998-03-02 | 2005-09-13 | Johnson & Johnson Vision Care, Inc. | Soft contact lenses |
| US20070043140A1 (en) * | 1998-03-02 | 2007-02-22 | Lorenz Kathrine O | Method for the mitigation of symptoms of contact lens related dry eye |
| US5962548A (en) * | 1998-03-02 | 1999-10-05 | Johnson & Johnson Vision Products, Inc. | Silicone hydrogel polymers |
| US6039913A (en) * | 1998-08-27 | 2000-03-21 | Novartis Ag | Process for the manufacture of an ophthalmic molding |
| USRE38935E1 (en) | 1998-10-29 | 2006-01-10 | Advanced Medical Optics, Inc. | Intraocular lenses made from polymeric compositions and monomers useful in said compositions |
| US6245106B1 (en) * | 1998-10-29 | 2001-06-12 | Allergan Sales, Inc. | Intraocular lenses made from polymeric compositions and monomers useful in said compositions |
| US6610220B1 (en) * | 1998-12-28 | 2003-08-26 | Johnson & Johnson Vision Care, Inc. | Process of manufacturing contact lenses with measured exposure to oxygen |
| JP4489975B2 (ja) * | 1999-03-30 | 2010-06-23 | ノバルティス アーゲー | 有機化合物 |
| US6638451B1 (en) * | 1999-08-31 | 2003-10-28 | Novartis Ag | Plastic casting molds |
| US6348604B1 (en) | 1999-09-17 | 2002-02-19 | Ppg Industries Ohio, Inc. | Photochromic naphthopyrans |
| US6296785B1 (en) | 1999-09-17 | 2001-10-02 | Ppg Industries Ohio, Inc. | Indeno-fused photochromic naphthopyrans |
| EP1754728B1 (de) * | 1999-10-07 | 2010-02-24 | Johson & Johnson Vision Care Inc. | Weiche Kontaktlinsen |
| EP1235866B1 (de) * | 1999-10-07 | 2006-08-09 | Johnson & Johnson Vision Care, Inc. | Weiche kontaktlinsen |
| DE60021595T3 (de) † | 1999-10-27 | 2011-08-18 | Novartis AG, 4056 | Entformung von kontakt-linsen |
| US6271192B1 (en) * | 1999-11-10 | 2001-08-07 | National Starch And Chemical Investment Holding Company | Associative thickener for aqueous fabric softener |
| EP1927882B1 (de) | 1999-12-10 | 2015-09-23 | Novartis AG | Kontaktlinse |
| US6649722B2 (en) | 1999-12-10 | 2003-11-18 | Novartis Ag | Contact lens |
| CA2394939C (en) * | 1999-12-16 | 2007-10-30 | Asahikasei Aime Co., Ltd. | Long-wearable soft contact lens |
| AU4232701A (en) * | 2000-01-05 | 2001-07-16 | Novartis Ag | Hydrogels |
| TW490802B (en) * | 2000-01-07 | 2002-06-11 | Sony Corp | Polysilicon evaluating method, polysilicon inspection apparatus and method for preparation of thin film transistor |
| JP2001201723A (ja) * | 2000-01-18 | 2001-07-27 | Asahi Kasei Aimii Kk | 連続装用ソフトコンタクトレンズ |
| US6719929B2 (en) | 2000-02-04 | 2004-04-13 | Novartis Ag | Method for modifying a surface |
| US6793973B2 (en) | 2000-02-04 | 2004-09-21 | Novartis Ag | Single-dip process for achieving a layer-by-layer-like coating |
| JP2003522227A (ja) | 2000-02-07 | 2003-07-22 | バイオコンパティブルズ リミテッド | シリコン含有化合物 |
| JP3929014B2 (ja) * | 2000-02-24 | 2007-06-13 | Hoyaヘルスケア株式会社 | 側鎖にポリシロキサン構造を有するマクロマーからなるコンタクトレンズ材料 |
| US7521519B1 (en) * | 2000-03-14 | 2009-04-21 | Novartis Ag | Organic compounds |
| ATE268358T1 (de) * | 2000-03-22 | 2004-06-15 | Menicon Co Ltd | Material für eine okularlinse |
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| US6291543B1 (en) | 2000-05-24 | 2001-09-18 | Polyzen, Inc. | Surfacially cross-linked elastoplastic articles, and method of making the same |
| US6779888B2 (en) | 2000-07-28 | 2004-08-24 | Ocular Sciences, Inc. | Contact lenses with microchannels |
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| US6852353B2 (en) | 2000-08-24 | 2005-02-08 | Novartis Ag | Process for surface modifying substrates and modified substrates resulting therefrom |
| AU2001289826A1 (en) | 2000-08-24 | 2002-03-04 | Novartis Ag | Process for surface modifying substrates and modified substrates resulting therefrom |
| JP5076256B2 (ja) * | 2000-09-05 | 2012-11-21 | 東レ株式会社 | モノマー組成物、それを用いたポリマーおよび眼用レンズ |
| CA2420861C (en) | 2000-09-19 | 2007-04-24 | Joseph A. Mcgee | Method for applying polymeric lens coating |
| EP1193056A1 (de) * | 2000-09-29 | 2002-04-03 | International Business Machines Corporation | Stempel aus Silikonelastomer mit hydrophilen Oberflächen und Verfahren zu seiner Herstellung |
| AU2733102A (en) | 2000-11-03 | 2002-05-15 | Johnson & Johnson Vision Care | Solvents useful in the preparation of polymers containing hydrophilic and hydrophobic monomers |
| DE10055762A1 (de) | 2000-11-10 | 2002-06-06 | Woehlk Contact Linsen Gmbh | Hydrogelkontaktlinsen mit hoher Biokompatibilität |
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