DE69927844T2 - N-substituierte 2-cyanopyrrolidine - Google Patents

N-substituierte 2-cyanopyrrolidine Download PDF

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Publication number
DE69927844T2
DE69927844T2 DE69927844T DE69927844T DE69927844T2 DE 69927844 T2 DE69927844 T2 DE 69927844T2 DE 69927844 T DE69927844 T DE 69927844T DE 69927844 T DE69927844 T DE 69927844T DE 69927844 T2 DE69927844 T2 DE 69927844T2
Authority
DE
Germany
Prior art keywords
amino
cyano
adamantyl
acetyl
pyrrolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE69927844T
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German (de)
English (en)
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DE69927844D1 (de
Inventor
Bernard Edwin VILLHAUER
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Novartis AG
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Novartis AG
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22777194&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69927844(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE69927844D1 publication Critical patent/DE69927844D1/de
Application granted granted Critical
Publication of DE69927844T2 publication Critical patent/DE69927844T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69927844T 1998-12-10 1999-12-09 N-substituierte 2-cyanopyrrolidine Expired - Lifetime DE69927844T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US209068 1980-11-21
US20906898A 1998-12-10 1998-12-10
PCT/EP1999/009708 WO2000034241A1 (en) 1998-12-10 1999-12-09 N-substituted 2-cyanopyrrolidines

Publications (2)

Publication Number Publication Date
DE69927844D1 DE69927844D1 (de) 2006-03-02
DE69927844T2 true DE69927844T2 (de) 2006-07-27

Family

ID=22777194

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69927844T Expired - Lifetime DE69927844T2 (de) 1998-12-10 1999-12-09 N-substituierte 2-cyanopyrrolidine
DE122008000007C Pending DE122008000007I1 (de) 1998-12-10 1999-12-09 N-substituierte 2-cyanopyrrolidine
DE122008000017C Pending DE122008000017I1 (de) 1998-12-10 1999-12-09 N-substituierte 2-cyanopyrrolidine

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE122008000007C Pending DE122008000007I1 (de) 1998-12-10 1999-12-09 N-substituierte 2-cyanopyrrolidine
DE122008000017C Pending DE122008000017I1 (de) 1998-12-10 1999-12-09 N-substituierte 2-cyanopyrrolidine

Country Status (34)

Country Link
US (1) US6166063A (cg-RX-API-DMAC7.html)
EP (1) EP1137635B1 (cg-RX-API-DMAC7.html)
JP (2) JP3681110B2 (cg-RX-API-DMAC7.html)
KR (2) KR20050047561A (cg-RX-API-DMAC7.html)
CN (1) CN1160330C (cg-RX-API-DMAC7.html)
AR (1) AR023719A1 (cg-RX-API-DMAC7.html)
AT (1) ATE307112T1 (cg-RX-API-DMAC7.html)
BR (1) BRPI9915985B8 (cg-RX-API-DMAC7.html)
CA (1) CA2350609C (cg-RX-API-DMAC7.html)
CO (1) CO5150173A1 (cg-RX-API-DMAC7.html)
CY (3) CY1105355T1 (cg-RX-API-DMAC7.html)
CZ (1) CZ299151B6 (cg-RX-API-DMAC7.html)
DE (3) DE69927844T2 (cg-RX-API-DMAC7.html)
DK (1) DK1137635T3 (cg-RX-API-DMAC7.html)
ES (1) ES2251847T3 (cg-RX-API-DMAC7.html)
FR (1) FR08C0005I2 (cg-RX-API-DMAC7.html)
HK (1) HK1040394B (cg-RX-API-DMAC7.html)
HU (1) HU226769B1 (cg-RX-API-DMAC7.html)
ID (1) ID28796A (cg-RX-API-DMAC7.html)
IL (2) IL143091A0 (cg-RX-API-DMAC7.html)
LU (2) LU91409I2 (cg-RX-API-DMAC7.html)
MY (1) MY123244A (cg-RX-API-DMAC7.html)
NL (2) NL300333I2 (cg-RX-API-DMAC7.html)
NO (3) NO318741B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ511935A (cg-RX-API-DMAC7.html)
PE (1) PE20001317A1 (cg-RX-API-DMAC7.html)
PL (1) PL199443B1 (cg-RX-API-DMAC7.html)
RU (1) RU2251544C2 (cg-RX-API-DMAC7.html)
SK (1) SK286635B6 (cg-RX-API-DMAC7.html)
TR (1) TR200101478T2 (cg-RX-API-DMAC7.html)
TW (1) TW509674B (cg-RX-API-DMAC7.html)
UY (1) UY25843A1 (cg-RX-API-DMAC7.html)
WO (1) WO2000034241A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200104581B (cg-RX-API-DMAC7.html)

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