CN103554205A - 调节gccr的表达的化合物和方法 - Google Patents

调节gccr的表达的化合物和方法 Download PDF

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Publication number
CN103554205A
CN103554205A CN201310168425.9A CN201310168425A CN103554205A CN 103554205 A CN103554205 A CN 103554205A CN 201310168425 A CN201310168425 A CN 201310168425A CN 103554205 A CN103554205 A CN 103554205A
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China
Prior art keywords
antisense compounds
nucleotide
certain embodiments
short antisense
target
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Pending
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CN201310168425.9A
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English (en)
Chinese (zh)
Inventor
S·巴诺特
R·S·吉尔里
R·麦凯
B·P·莫尼亚
P·P·塞思
A·M·休科夫斯基
E·E·施韦策
E·万斯维奇
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Ionis Pharmaceuticals Inc
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Isis Pharmaceuticals Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40134111&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN103554205(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US2007/061183 external-priority patent/WO2007090071A2/en
Application filed by Isis Pharmaceuticals Inc filed Critical Isis Pharmaceuticals Inc
Publication of CN103554205A publication Critical patent/CN103554205A/zh
Pending legal-status Critical Current

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    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/323—Chemical structure of the sugar modified ring structure
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    • C12N2310/341—Gapmers, i.e. of the type ===---===
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    • C12N2310/351—Conjugate
    • C12N2310/3515—Lipophilic moiety, e.g. cholesterol

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CN201310168425.9A 2006-05-05 2007-05-07 调节gccr的表达的化合物和方法 Pending CN103554205A (zh)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US74663106P 2006-05-05 2006-05-05
US60/746,631 2006-05-05
US74705906P 2006-05-11 2006-05-11
US60/747,059 2006-05-11
US80566006P 2006-06-23 2006-06-23
US60/805,660 2006-06-23
US86455406P 2006-11-06 2006-11-06
US60/864,554 2006-11-06
USPCT/US2007/061183 2007-01-27
PCT/US2007/061183 WO2007090071A2 (en) 2006-01-27 2007-01-27 6-modified bicyclic nucleic acid analogs

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CNA2007800254167A Division CN101553236A (zh) 2006-05-05 2007-05-07 调节gccr的表达的化合物和方法

Publications (1)

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CN103554205A true CN103554205A (zh) 2014-02-05

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CN201310168425.9A Pending CN103554205A (zh) 2006-05-05 2007-05-07 调节gccr的表达的化合物和方法

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US (14) US20090326042A1 (enExample)
EP (10) EP2505646A1 (enExample)
JP (7) JP5731115B2 (enExample)
KR (1) KR101441700B1 (enExample)
CN (1) CN103554205A (enExample)
AT (2) ATE513912T1 (enExample)
AU (4) AU2007258117B2 (enExample)
BR (1) BRPI0711429A2 (enExample)
CA (3) CA2651309C (enExample)
DK (5) DK2015758T3 (enExample)
ES (2) ES2471978T3 (enExample)
MX (1) MX2008014100A (enExample)
NO (1) NO20084738L (enExample)
PT (1) PT2015758E (enExample)
WO (9) WO2007143316A2 (enExample)

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