AU2001251612A1 - Roles of jak/stat family members in tolerance induction - Google Patents
Roles of jak/stat family members in tolerance inductionInfo
- Publication number
- AU2001251612A1 AU2001251612A1 AU2001251612A AU5161201A AU2001251612A1 AU 2001251612 A1 AU2001251612 A1 AU 2001251612A1 AU 2001251612 A AU2001251612 A AU 2001251612A AU 5161201 A AU5161201 A AU 5161201A AU 2001251612 A1 AU2001251612 A1 AU 2001251612A1
- Authority
- AU
- Australia
- Prior art keywords
- jak
- roles
- family members
- tolerance induction
- stat family
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000024664 tolerance induction Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54965400A | 2000-04-14 | 2000-04-14 | |
US09/549,654 | 2000-04-14 | ||
PCT/US2001/012131 WO2001079555A2 (en) | 2000-04-14 | 2001-04-13 | Roles of jak/stat family members in tolerance induction |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001251612A1 true AU2001251612A1 (en) | 2001-10-30 |
Family
ID=24193892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001251612A Abandoned AU2001251612A1 (en) | 2000-04-14 | 2001-04-13 | Roles of jak/stat family members in tolerance induction |
Country Status (3)
Country | Link |
---|---|
US (1) | US6534277B1 (en) |
AU (1) | AU2001251612A1 (en) |
WO (1) | WO2001079555A2 (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7888324B2 (en) * | 2001-08-01 | 2011-02-15 | Genzyme Corporation | Antisense modulation of apolipoprotein B expression |
US7407943B2 (en) * | 2001-08-01 | 2008-08-05 | Isis Pharmaceuticals, Inc. | Antisense modulation of apolipoprotein B expression |
AU2003207273A1 (en) * | 2002-02-27 | 2003-09-09 | Genox Research, Inc. | Method of examining allergic disease |
US20040101853A1 (en) * | 2002-11-23 | 2004-05-27 | Isis Pharmaceuticals Inc. | Modulation of STAT2 expression |
JP4484708B2 (en) * | 2002-09-27 | 2010-06-16 | 穣 藤本 | Methods for treating autoimmune diseases and methods for screening for therapeutic compounds for autoimmune diseases |
US7511131B2 (en) | 2002-11-13 | 2009-03-31 | Genzyme Corporation | Antisense modulation of apolipoprotein B expression |
US20060009410A1 (en) * | 2002-11-13 | 2006-01-12 | Crooke Rosanne M | Effects of apolipoprotein B inhibition on gene expression profiles in animals |
DK1639014T3 (en) * | 2003-06-13 | 2011-01-17 | Biogen Idec Inc | Aglycosyl anti-CD154 (CD40 ligand) antibodies and uses thereof |
AU2011224032B2 (en) * | 2003-06-13 | 2013-01-31 | Biogen Ma Inc. | Aglycosyl Anti-CD154 (CD40 Ligand) Antibodies and Uses Thereof |
AU2004252395A1 (en) * | 2003-06-30 | 2005-01-06 | Biovitrum Ab (Publ) | Methods for identifying agents, which regulate cytokines |
JP4664815B2 (en) * | 2003-09-11 | 2011-04-06 | ヒュービットジェノミクス株式会社 | Method and kit for detecting proliferative disease causing sclerosis, prophylactic and / or therapeutic agent for proliferative disease causing sclerosis, and method and kit for identifying substances effective for prevention and / or treatment of proliferative disease causing sclerosis |
US20050287558A1 (en) * | 2004-05-05 | 2005-12-29 | Crooke Rosanne M | SNPs of apolipoprotein B and modulation of their expression |
US20060003940A1 (en) * | 2004-05-11 | 2006-01-05 | Rong-Hwa Lin | T-cell death-inducing epitopes |
RS20070027A (en) | 2004-07-26 | 2008-11-28 | Biogen Idec Ma Inc., | Anti-cd154 antibodies |
FI20041204A0 (en) | 2004-09-16 | 2004-09-16 | Riikka Lund | Methods for the utilization of new target genes associated with immune-mediated diseases |
WO2006044666A2 (en) * | 2004-10-15 | 2006-04-27 | Northeastern University | Detection of disease associated proteolysis by direct mass spectrometry analysis of low molecular weight peptides |
FR2877013A1 (en) | 2004-10-27 | 2006-04-28 | Assist Publ Hopitaux De Paris | INDENTIFICATION OF A JAK2 MUTATION INVOLVED IN THE VAQUEZ POLYGLOBULIA |
AU2007253909B2 (en) * | 2006-05-05 | 2012-08-09 | Isis Pharmaceuticals, Inc. | Compounds and methods for modulating expression of GCCR |
WO2008118883A1 (en) * | 2007-03-24 | 2008-10-02 | Isis Pharmaceuticals, Inc. | Administering antisense oligonucleotides complementary to human apolipoprotein b |
US9107933B2 (en) | 2009-03-16 | 2015-08-18 | Isis Pharmaceuticals, Inc. | Compositions and methods of targeting apolipoprotein B for the reduction of apolipoprotein C-III |
DE102009027754A1 (en) * | 2009-07-15 | 2011-05-05 | Schubert, Ulrich, Dr. | Method for inhibiting the maturation of dendritic cells |
TWI688395B (en) | 2010-03-23 | 2020-03-21 | 英翠克頌公司 | Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof |
US10633704B2 (en) | 2010-07-23 | 2020-04-28 | Raymond M. Johnson | Diagnostic and immunotherapy compositions and methods for disease states mediated by inhibitor-resistant CD8 T-cells |
WO2012012797A2 (en) * | 2010-07-23 | 2012-01-26 | Indiana University Research And Technology Corporation | Methods for isolating and using a subset of cd8 t-cells that are resistant to cyclosporin |
AU2017298385A1 (en) * | 2016-07-19 | 2019-03-07 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Oncolytic viruses targeting STAT3 |
JP6750443B2 (en) * | 2016-10-05 | 2020-09-02 | ソニー株式会社 | Platelet aggregation analysis method, platelet aggregation analysis device, platelet aggregation analysis program, and platelet aggregation analysis system |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0667901B2 (en) | 1991-10-25 | 2008-10-15 | Immunex Corporation | Novel cytokine |
US5961974A (en) | 1991-10-25 | 1999-10-05 | Immunex Corporation | Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same |
US5981724A (en) | 1991-10-25 | 1999-11-09 | Immunex Corporation | DNA encoding CD40 ligand, a cytokine that binds CD40 |
US5962406A (en) | 1991-10-25 | 1999-10-05 | Immunex Corporation | Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same |
US5474771A (en) | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
US5980954A (en) * | 1992-02-07 | 1999-11-09 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
CA2089229C (en) | 1992-02-14 | 2010-04-13 | Alejandro A. Aruffo | Cd40cr receptor and ligands therefor |
AU4535893A (en) * | 1992-06-15 | 1994-01-04 | Regents Of The University Of California, The | Screening assay for the identification of immunosuppressive drugs |
US5540926A (en) | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
US5565321A (en) | 1993-01-22 | 1996-10-15 | Immunex Corporation | Detection of mutations in a CD40 ligand gene |
DE69433399T2 (en) | 1993-01-22 | 2004-10-14 | Immunex Corp., Seattle | DETECTION AND TREATMENT OF MUTATIONS IN A GENE FOR A CD40 LIGAND |
ZA946765B (en) | 1993-09-02 | 1996-02-15 | Dartmouth College | Methods of prolonged suppression of humoral immunity |
EP0742721B1 (en) | 1993-09-02 | 1999-05-06 | Trustees of Dartmouth College | Methods of prolonged suppression of humoral immunity |
CN1127351C (en) | 1993-09-02 | 2003-11-12 | 达特茅斯学院理事 | Method for inducing antigen-specific T cell tolerance |
US5869049A (en) | 1993-09-02 | 1999-02-09 | Trustees Of Dartmouth College | Methods of inducing T cell unresponsiveness to bone marrow with gp39 antagonists |
US5527884A (en) * | 1993-12-21 | 1996-06-18 | President And Fellows Of Harvard College | Mediators of chronic allograft rejection and DNA molecules encoding them |
AU680102B2 (en) | 1993-12-23 | 1997-07-17 | Immunex Corporation | Method of preventing or treating disease characterized by neoplastic cells expressing CD40 |
US5580979A (en) | 1994-03-15 | 1996-12-03 | Trustees Of Tufts University | Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions |
US5683693A (en) | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
US5563036A (en) | 1994-04-29 | 1996-10-08 | Tularik, Inc. | Transcription factor-DNA binding assay |
US5583713A (en) * | 1994-07-22 | 1996-12-10 | Analog Devices, Inc. | Pipelined demodulation and ADC conversion scheme for disk drive servo system |
US5876950A (en) | 1995-01-26 | 1999-03-02 | Bristol-Myers Squibb Company | Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy |
US5821053A (en) * | 1995-02-10 | 1998-10-13 | Center For Blood Research, Inc. | LIL-Stat DNA binding sites and methods for identifying inhibitory binding agents |
US5710129A (en) | 1995-02-23 | 1998-01-20 | Ariad Pharmaceuticals, Inc. | Inhibitors of SH2-mediated processes |
US6066322A (en) * | 1995-03-03 | 2000-05-23 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of immune disorders |
US5712094A (en) | 1995-03-27 | 1998-01-27 | Ligand Pharmaceuticals, Inc. | Methods for detecting modulators of cytokine action |
KR100453314B1 (en) | 1995-06-07 | 2004-12-17 | 임뮤넥스 코포레이션 | CD40L Mutein |
US5833987A (en) | 1995-06-07 | 1998-11-10 | Trustees Of Dartmouth College | Treatment of T cell mediated autoimmune disorders |
US6440418B1 (en) | 1995-11-07 | 2002-08-27 | Idec Pharmaceuticals Corporation | Methods of treating autoimmune diseases with gp39-specific antibodies |
US6001358A (en) | 1995-11-07 | 1999-12-14 | Idec Pharmaceuticals Corporation | Humanized antibodies to human gp39, compositions containing thereof |
US6340459B1 (en) | 1995-12-01 | 2002-01-22 | The Trustees Of Columbia University In The City Of New York | Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients |
WO1997039722A2 (en) * | 1996-04-25 | 1997-10-30 | T Cell Sciences, Inc. | Method of isolating regulators of t cell activation |
DE69738767D1 (en) * | 1996-11-01 | 2008-07-24 | Inst Medical W & E Hall | THERAPEUTICS AND DIAGNOSTICS THAT REGULATE CELLULAR RESPONSABILITY ON CYTOKINES |
CA2277223A1 (en) | 1997-01-10 | 1998-07-16 | Biogen, Inc. | Methods of therapeutic administration of anti-cd40l compounds |
US5932425A (en) | 1997-02-18 | 1999-08-03 | Signal Pharmaceuticals, Inc. | Compositions and methods for modulating cellular NF-κB activation |
AU5623398A (en) | 1997-03-07 | 1998-09-22 | Biogen, Inc. | Methods of therapeutic administration of anti-cd40l compounds |
TR199902817T2 (en) | 1997-05-17 | 2000-09-21 | Biogen, Inc. | Use of a CD40:CD154 binding interfering agent for inhibition of counter-adaptive bonding reactions, in particular graft rejection . |
TR199903141T2 (en) | 1997-06-20 | 2000-09-21 | Biogen, Inc. | CD154 blockade therapy for therapeutic protein blocker syndrome. |
DE69835965T2 (en) | 1997-06-20 | 2007-06-14 | Biogen Idec Ma Inc., Cambridge | CD154-BLOCKADETHERAPY OF PANCREAS ISOLATED TRANSPLANTATION in primates |
AU8266798A (en) | 1997-06-27 | 1999-01-19 | Biogen, Inc. | Cd154 blockade therapy for autoimmune diseases |
WO1999045958A1 (en) | 1998-03-09 | 1999-09-16 | Biogen, Inc. | Cd154 blockade therapy for modulation of immune responses to implanted devices |
US6207391B1 (en) * | 1998-03-31 | 2001-03-27 | Tularik Inc. | High-throughput screening assays for modulators of STAT4 and STAT6 activity |
-
2001
- 2001-04-13 WO PCT/US2001/012131 patent/WO2001079555A2/en active Application Filing
- 2001-04-13 AU AU2001251612A patent/AU2001251612A1/en not_active Abandoned
- 2001-10-05 US US09/972,800 patent/US6534277B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6534277B1 (en) | 2003-03-18 |
WO2001079555A2 (en) | 2001-10-25 |
WO2001079555A3 (en) | 2003-02-27 |
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