JP2002355074A - 腸管出血性病原性大腸菌ｏ１５７：ｈ７に特異的な核酸分子およびポリペプチド並びにこれらの使用方法 - Google Patents

Abstract

(57)【要約】 【課題】 腸管出血性病原性大腸菌Ｏ１５７：Ｈ７感染
の検出および／または治療に有用となりうる核酸および
アミノ酸配列並びにこれらの使用方法を提供する。 【解決手段】 Ｏ１５７の全遺伝情報を解析することに
より、Ｏ１５７特異的な新規核酸分子、これに包含され
る新規遺伝子、前記遺伝子によりコードされる新規ポリ
ペプチドの遺伝情報を明らかにする。

Description

【発明の詳細な説明】

【０００１】

【産業上の利用分野】本発明は、新規なＯ１５７：Ｈ７
に特異的な核酸分子およびポリペプチド、並びにそれら
の使用に関する。

【０００２】

【従来の技術】大腸菌は健康な人の大腸内などにも生息
し、特にほとんどの大腸菌は病気を起こすことはない。
しかし一部の大腸菌は、ヒトの腸管に感染して胃腸炎や
下痢症など食中毒を引き起こすものがあり、これらは病
原性大腸菌と称され、下記するように主に５つのカテゴ
リーに分類されている： 毒素原性大腸菌(Enterotoxigenic Escherichia coli；E
TEC) 組織侵入性大腸菌(Enteroinvasive Escherichia coli；
EIEC) 腸管病原性大腸菌(Enteropathogenic Escherichia col
i；EPEC) 腸管出血性大腸菌 (Enterohemorrhagic Escherichia co
li；EHEC) 腸管付着性大腸菌 (Enteroadherent Escherichia coli
; EAEC)

【０００３】その中の腸管出血性大腸菌には、激しい腹
痛、下痢および／または血便を主な症状として、特に小
児や高齢者に腎臓障害、溶血性尿毒症症候群（ＨＵＳ）
など重篤な合併症を引き起こし、場合により患者を死に
至らしめる大腸菌も含まれている。その主な原因菌はＯ
１５７：Ｈ７（以後、Ｏ１５７と称する）である。Ｏ１
５７は、それまでに報告されていた腸管病原性大腸菌や
腸管侵入性大腸菌の血清型とは異なる血清型に属し、且
つ易熱性エンテロトキシン（ＬＴ）および耐熱性エンテ
ロトキシン（ＳＴ）を産生しない病原性大腸菌として、
Riley等（RileyLW, et al., N. Engl. J. Med. 308 (19
83), p.681-685 ）により報告された。また、Ｏ１５７
を含めて腸管出血性大腸菌は、産生する細胞外毒素がベ
ロ毒素（Verotoxin；ＶＴ）であることが明らかになっ
たことから、近年はベロ毒素産生性大腸菌(Verotoxin-p
roducing Escherichia coli ；ＶＴＥＣ)とも称されて
いる。

【０００４】ＥＨＥＣ（またはＶＴＥＣ）により産生さ
れるベロ毒素（ＶＴ）は、アフリカミドリザルの腎臓由
来細胞であるベロ細胞に対して強い細胞毒性を有してい
るものとして同定された。O'Brien等（O'Brien et al.,
J. Infect Dis. 146 (1982), p.763-769）は、この毒
性が赤痢菌が産生する志賀毒素に対する抗体で中和され
ることを報告し、志賀毒素様毒素（Shiga-1ike toxin）
と呼称した。ベロ毒素には二つの主要なタイプ（ＶＴ１
およびＶＴ２）があり、志賀毒素に似ているところから
それぞれＳＬＴ１（Shiga-Like Toxin １）およびＳＬ
Ｔ２とも称されている。ＶＴ１は志賀毒素と同一かまた
は１アミノ酸においてのみ相違している。ＶＴ２はＶＴ
１とアミノ酸レベルで約５６％の相同性を有している
（JacksonM.P. et al., FEMS Micorobial Lett. 44 (19
87) p. 109-114）が、その抗原性についてはほとんど共
通性はない。このベロ毒素や志賀毒素は植物由来の強力
な植物毒素のリシンと同じRNA N-グリコシダーゼ活性を
有している。その作用機序は、哺乳動物真核生物の60S
リボソームを構成する28SリボソームRNA中のアデノシン
のN-グリコシド結合を加水分解することにより、アミノ
アシルtRNAのリボソームへの結合を阻害してタンパク合
成を阻害するというものであり、このため細胞は死に至
る。特にベロ毒素は、大腸等の血管内皮細胞、尿細管の
細胞に障害を与え、溶血性尿毒症候群等を引き起こす。

【０００５】上述のように、Ｏ１５７は出血性大腸炎を
引き起こし、さらには患者の生命の危険を伴う溶血性尿
毒症候群や脳症を併発することがある。これまで溶血性
尿毒症候群への進展を防止または予防する有効な方法は
確立されておらず、また抗生物質などの抗菌剤の投与に
より菌体外へのＶＴの放出を促進して、却って症状を悪
化させてしまう場合がある。このため、感染初期におい
て確定的な感染の診断が重要である。

【０００６】Ｏ１５７感染の診断方法、即ちＯ１５７と
非病原性または他の病原性大腸菌とを区別する方法とし
て、いくつかの方法が知られている。その１つは、Ｏ１
５７:Ｈ７菌が一般の大腸菌や他の既知腸管病原性大腸
菌と異なりβ−グルクロニダーゼを産生せず，また糖類
のソルビト−ルを非または遅れて発酵するという特徴を
利用するものであり、広く利用されている。しかし、こ
れらの方法は検査に時間を要し、迅速性に欠けるという
欠点がある。また、ソルビトール分解能を有するＯ１５
７の存在も報告されており、これらの方法はそのような
菌を検出できない。他方、Ｏ１５７リポポリサッカライ
ド抗原に対する抗体またはベロ毒素に対する抗体を利用
した逆受身ラテックス凝集反応が知られている。これら
の方法は、迅速簡便にVT産生の菌を検出することができ
るが、検出感度が十分ではない。特にベロ毒素について
は毒素産生菌はＯ１５７に限定されているわけではな
く、Ｏ１５７の検出法としては問題がある。

【０００７】さらにＯ１５７の検出法として、分子生物
学的方法、具体的にはハイブリダイゼーション法および
ＰＣＲ法が行われている。特にＰＣＲ法は極めて検出感
度が高く、且つ簡便・迅速性が高いため、近年その利用
が増えてきている。ＰＣＲ法等が標的とするのは主にＯ
１５７などＶＴＥＣが有するＶＴ遺伝子である。しか
し、上述のようにＶＴ遺伝子はＯ１５７以外の大腸菌も
有しており、さらにＶＴ遺伝子には複数の変異体が知ら
れており、Ｏ１５７の確定的な診断方法としては問題が
ある。また、パルスフィールドゲル電気泳動法（PFGE;
pulsed-field gel electrophoresis）がＯ１５７の検出
に使用されているが、該方法に必要な装置は高価であ
り、検査に要する時間も長く、且つかなり熟練した技術
を要する。また、一度の解析できる菌株の数も限られる
ほか、異なる施設間でのＯ１５７のデータの比較も容易
ではない。そこで、迅速・簡便で検出感度が高く、且つ
信頼性が高く、異なる施設間でのデータの比較・交換が
容易な方法が求められている。

【０００８】一方、Ｏ１５７またはＶＴＥＣに有効とさ
れる抗生物質などの抗菌剤が知られているが、薬剤耐性
菌の存在も報告されている。また上述のように抗生物質
の投与によりＶＴが菌体外に放出され、患者の症状を悪
化させてしまう場合もある。このため、これら抗菌剤に
よるＯ１５７感染症の治療法とは別の方法の開発、ＶＴ
により引き起こされる症状の治療および／または予防方
法、並びにその手がかりとなりうるＯ１５７の詳細な遺
伝情報が求められている。

【０００９】

【発明が解決しようとする課題】そこで、本発明の課題
は、腸管出血性病原性大腸菌Ｏ１５７：Ｈ７感染の検出
および／または治療に有用となりうる核酸分子およびポ
リペプチド、並びにこれらの遺伝情報および使用方法を
提供することである。

【００１０】

【課題を解決するための手段】本発明者等は、腸管出血
性病原性大腸菌Ｏ１５７：Ｈ７堺株（RIMD 0509952）の
全遺伝情報を解析し、非病原性大腸菌を含め他の大腸菌
にはなく、Ｏ１５７：Ｈ７に特異的な遺伝情報を見出し
た。故に、本発明は、Ｏ１５７：Ｈ７に特異的な遺伝情
報およびそれらの使用に関する。遺伝情報には、ゲノム
上のヌクレオチド配列、遺伝子およびこれにコードされ
るポリペプチドおよびそのアミノ酸配列等が包含される
が、これらに限定されるわけでない。

【００１１】従って、本発明は、腸管出血性病原性大腸
菌Ｏ１５７：Ｈ７に特異的な核酸分子に関する。好まし
い態様において本発明は、（ａ）SEQ ID NO：1, SEQ ID
NO：132, SEQ ID NO：244, SEQ ID NO：337, SEQID N
O：410, SEQ ID NO：484, SEQ ID NO：554, SEQ ID N
O：630, SEQ ID NO：689, SEQ ID NO：755, SEQ ID N
O：816, SEQ ID NO：876, SEQ ID NO：927, SEQID NO：
978, SEQ ID NO：1013, SEQ ID NO：1029, SEQ ID NO：
1055, SEQ ID NO：1060, SEQ ID NO：1093, SEQ ID N
O：1128, SEQ ID NO：1157, SEQ ID NO：1191, SEQ ID
NO：1212, SEQ ID NO：1240, SEQ ID NO：1258, SEQ ID
NO：1274,SEQ ID NO：1288, SEQ ID NO：1302, SEQ ID
NO：1309, SEQ ID NO：1321, SEQID NO：1329, SEQ ID
NO：1338, SEQ ID NO：1348, SEQ ID NO：1359, SEQ I
D NO：1366, SEQ ID NO：1374, SEQ ID NO：1380, SEQ
ID NO：1386, SEQ ID NO：1394, SEQ ID NO：1401, SEQ
ID NO：1408, SEQ ID NO：1411, SEQ ID NO：1418,SEQ
ID NO：1426, SEQ ID NO：1436, SEQ ID NO：1443, SE
Q ID NO：1450, SEQID NO：1457, SEQ ID NO：1460, SE
Q ID NO：1467, SEQ ID NO：1471, SEQ IDNO：1473, SE
Q ID NO：1478, SEQ ID NO：1487, SEQ ID NO：1489, S
EQ ID NO：1494, SEQ ID NO：1499, SEQ, ID NO：1501,
SEQ ID NO：1506, SEQ ID NO：1508, SEQ ID NO：151
0, SEQ ID NO：1511, SEQ ID NO：1516, SEQ ID NO：15
20, SEQ ID NO：1526, SEQ ID NO：1532, SEQ ID NO：1
537, SEQ ID NO：1540, SEQ ID NO：1545, SEQ ID NO：
1547, SEQ ID NO：1549, SEQ ID NO：1551, SEQ ID N
O：1553, SEQ ID NO：1555, SEQ ID NO：1558, SEQ ID
NO：1563, SEQ ID NO：1566, SEQ ID NO：1569, SEQ ID
NO：1571, SEQ ID NO：1576, SEQ ID NO：1580,SEQ ID
NO：1584, SEQ ID NO：1587, SEQ ID NO：1591, SEQ I
D NO：1594, SEQID NO：1596, SEQ ID NO：1599, SEQ I
D NO：1601, SEQ ID NO：1603, SEQ ID NO：1604, SEQ
ID NO：1605, SEQ ID NO：1607, SEQ ID NO：1612, SEQ
ID NO：1615, SEQ ID NO：1617, SEQ ID NO：1619, SE
Q ID NO：1622, SEQ ID NO：1624,SEQ ID NO：1626, SE
Q ID NO：1627, SEQ ID NO：1629, SEQ ID NO：1632, S
EQID NO：1635, SEQ ID NO：1636, SEQ ID NO：1637, S
EQ ID NO：1639, SEQ IDNO：1640, SEQ ID NO：1643, S
EQ ID NO：1646, SEQ ID NO：1649, SEQ ID NO：1652,
SEQ ID NO：1655, SEQ ID NO：1658, SEQ ID NO：1660,
SEQ ID NO：1662, SEQ ID NO：1664, SEQ ID NO：166
6, SEQ ID NO：1668, SEQ ID NO：1669, SEQ ID NO：16
70, SEQ ID NO：1672, SEQ ID NO：1673, SEQ ID NO：1
675, SEQ IDNO：1677, SEQ ID NO：1680, SEQ ID NO：1
682, SEQ ID NO：1683, SEQ ID NO：1685, SEQ ID NO：
1688, SEQ ID NO：1690, SEQ ID NO：1691, SEQ ID N
O：1694, SEQ ID NO：1696, SEQ ID NO：1699, SEQ ID
NO：1700, SEQ ID NO：1701,SEQ ID NO：1704, SEQ ID
NO：1705, SEQ ID NO：1706, SEQ ID NO：1707, SEQID
NO：1708, SEQ ID NO：1709, SEQ ID NO：1710, SEQ ID
NO：1711, SEQ ID NO：1712, SEQ ID NO：1713, SEQ I
D NO：1715, SEQ ID NO：1716, SEQ ID NO：1717, SEQ
ID NO：1718,, SEQ ID NO：1719, SEQ ID NO：1720, SE
Q ID NO：1721, SEQ ID NO：1722, SEQ ID NO：1723, S
EQ ID NO：1724, SEQ ID NO：1725, SEQ ID NO：1726,
SEQ ID NO：1727, SEQ ID NO：1728, SEQ ID NO：1729,
SEQ IDNO：1730, SEQ ID NO：1731, SEQ ID NO：1732,
SEQ ID NO：1733, SEQ ID NO：1734, SEQ ID NO：173
5, SEQ ID NO：1736, SEQ ID NO：1737, SEQ ID NO：17
38, SEQ ID NO：1739, SEQ ID NO：1740, SEQ ID NO：1
741, SEQ ID NO：1742,SEQ ID NO：1743, SEQ ID NO：1
744, SEQ ID NO：1745, SEQ ID NO：1746, SEQID NO：1
747, SEQ ID NO：1748, SEQ ID NO：1749, SEQ ID NO：
1750, SEQ ID NO：1751, SEQ ID NO：1752, SEQ ID N
O：1753, SEQ ID NO：1754, SEQ ID NO：1755, SEQ ID
NO：1756, SEQ ID NO：1757, SEQ ID NO：1758, SEQ ID
NO：1759,SEQ ID NO：1760, SEQ ID NO：1761, SEQ ID
NO：1762, SEQ ID NO：1763, SEQID NO：1764, SEQ ID
NO：1765, SEQ ID NO：1766, SEQ ID NO：1767, SEQ I
DNO：1768, SEQ ID NO：1769, SEQ ID NO：1770, SEQ I
D NO：1771, SEQ ID NO：1772, SEQ ID NO：1773, SEQ
ID NO：1774, SEQ ID NO：1775, SEQ ID NO：1776, SEQ
ID NO：1777, SEQ ID NO：1778, SEQ ID NO：1779, SE
Q ID NO：1780, SEQ ID NO：1781, SEQ ID NO：1782, S
EQ ID NO：1783, SEQ ID NO：1784, SEQ IDNO：1785, S
EQ ID NO：1786, SEQ ID NO：1787, SEQ ID NO：1788,
SEQ ID NO：1789, SEQ ID NO：1790, SEQ ID NO：1791,
SEQ ID NO：1792, SEQ ID NO：1793, SEQ ID NO：179
4, SEQ ID NO：1795, SEQ ID NO：1796, SEQ ID NO：17
97,SEQ ID NO：1798, SEQ ID NO：1799, SEQ ID NO：18
00, SEQ ID NO：1801, SEQID NO：1802, SEQ ID NO：18
03, SEQ ID NO：1804, SEQ ID NO：1805, SEQ ID NO：1
806, SEQ ID NO：1807, SEQ ID NO：1808, SEQ ID NO：
1809, SEQ ID NO：1810, SEQ ID NO：1811, SEQ ID N
O：1812, SEQ ID NO：1813, SEQ ID NO：1814,SEQ ID N
O：1815, SEQ ID NO：1816, SEQ ID NO：1817, SEQ ID
NO：1818, SEQID NO：1819, SEQ ID NO：1820, SEQ ID
NO：1821, SEQ ID NO：1822, SEQ IDNO：1823, SEQ ID
NO：1824, SEQ ID NO：1825, SEQ ID NO：1826, SEQ ID
NO：1827, SEQ ID NO：1828, SEQ ID NO：1829, SEQ I
D NO：1830, SEQ ID NO：1831, SEQ ID NO：1832, SEQ
ID NO：1833, SEQ ID NO：1834, SEQ ID NO：1835, SEQ
ID NO：1836, SEQ ID NO：1837, SEQ ID NO：1838, SE
Q ID NO：1839, SEQ IDNO：1840, SEQ ID NO：1841, SE
Q ID NO：1842, SEQ ID NO：1843, SEQ ID NO：1844, S
EQ ID NO：1845, SEQ ID NO：1846, SEQ ID NO：1847,
SEQ ID NO：1848, SEQ ID NO：1849, SEQ ID NO：1850,
SEQ ID NO：1851, SEQ ID NO：1852,SEQ ID NO：1853,
SEQ ID NO：1854, SEQ ID NO：1855, SEQ ID NO：185
6, SEQID NO：1857, SEQ ID NO：1858, SEQ ID NO：185
9, SEQ ID NO：1860, SEQ ID NO：1861, SEQ ID NO：18
62, SEQ ID NO：1863, SEQ ID NO：1864, SEQ ID NO：1
865, およびSEQ ID NO：1866からなる群から選択される
ヌクレオチド配列；（ｂ）（ａ）に記載のヌクレオチド
配列の部分配列；（ｃ）（ａ）もしくは（ｂ）に記載の
ヌクレオチド配列と相補的なヌクレオチド配列；または
（ｄ）（ａ）、（ｂ）もしくは（ｃ）に記載のヌクレオ
チド配列とストリンジェントな条件下でハイブリダイズ
するヌクレオチド配列を有することを特徴とする核酸分
子に関する。これら本発明の核酸分子は、多数のＯ１５
７特異的遺伝子を包含し、これらはO157特異的なタンパ
ク質またはポリペプチドをコードしている。

【００１２】従って、本発明は、腸管出血性病原性大腸
菌Ｏ１５７：Ｈ７に特異的なポリペプチドをコードする
核酸分子であって、（ａ）SEQ ID NO：2, SEQ ID NO：
3, SEQ ID NO：4, SEQ ID NO：5, SEQ ID NO：6, SEQ I
D NO：7, SEQ ID NO：8, SEQ ID NO：9, SEQ ID NO：1
0, SEQ ID NO：11, SEQ ID NO：12, SEQ ID NO：13, SE
Q ID NO：14, SEQ ID NO：15, SEQ IDNO：16, SEQ ID N
O：17, SEQ ID NO：18, SEQ ID NO：19, SEQ ID NO：2
0, SEQID NO：21, SEQ ID NO：22, SEQ ID NO：23, SEQ
ID NO：24, SEQ ID NO：25,SEQ ID NO：26, SEQ ID N
O：27, SEQ ID NO：28, SEQ ID NO：29, SEQ ID NO：3
0, SEQ ID NO：31, SEQ ID NO：32, SEQ ID NO：33, SE
Q ID NO：34, SEQ ID NO：35, SEQ ID NO：36, SEQ ID
NO：37, SEQ ID NO：38, SEQ ID NO：39, SEQ IDNO：4
0, SEQ ID NO：41, SEQ ID NO：42, SEQ ID NO：43, SE
Q ID NO：44, SEQID NO：45, SEQ ID NO：46, SEQ ID N
O：47, SEQ ID NO：48, SEQ ID NO：49,SEQ ID NO：50,
SEQ ID NO：51, SEQ ID NO：52, SEQ ID NO：53, SEQ
ID NO：54, SEQ ID NO：55, SEQ ID NO：56, SEQ ID N
O：57, SEQ ID NO：58, SEQ ID NO：59, SEQ ID NO：6
0, SEQ ID NO：61, SEQ ID NO：62, SEQ ID NO：63, SE
Q IDNO：64, SEQ ID NO：65, SEQ ID NO：66, SEQ ID N
O：67, SEQ ID NO：68, SEQID NO：69, SEQ ID NO：70,
SEQ ID NO：71, SEQ ID NO：72, SEQ ID NO：73,SEQ I
D NO：74, SEQ ID NO：75, SEQ ID NO：76, SEQ ID N
O：77, SEQ ID NO：78, SEQ ID NO：79, SEQ ID NO：8
0, SEQ ID NO：81, SEQ ID NO：82, SEQ ID NO：83, SE
Q ID NO：84, SEQ ID NO：85, SEQ ID NO：86, SEQ ID
NO：87, SEQ IDNO：88, SEQ ID NO：89, SEQ ID NO：9
0, SEQ ID NO：91, SEQ ID NO：92, SEQID NO：93, SEQ
ID NO：94, SEQ ID NO：95, SEQ ID NO：96, SEQ ID N
O：97,SEQ ID NO：98, SEQ ID NO：99, SEQ ID NO：10
0, SEQ ID NO：101, SEQ ID NO：102, SEQ ID NO：103,
SEQ ID NO：104, SEQ ID NO：105, SEQ ID NO：106, S
EQ ID NO：107, SEQ ID NO：108, SEQ ID NO：109, SEQ
ID NO：110, SEQ ID NO：111, SEQ ID NO：112, SEQ I
D NO：113, SEQ ID NO：114, SEQ ID NO：115, SEQ ID
NO：116, SEQ ID NO：117, SEQ ID NO：118, SEQ ID N
O：119, SEQ ID NO：120, SEQ ID NO：121, SEQ ID N
O：122, SEQ ID NO：123, SEQ ID NO：124, SEQ ID N
O：125, SEQ ID NO：126, SEQ ID NO：127, SEQ ID N
O：128, SEQ ID NO：129, SEQ ID NO：130, SEQ ID N
O：131, SEQ ID NO：133, SEQ ID NO：134, SEQ ID N
O：135, SEQ ID NO：136, SEQ ID NO：137, SEQ ID N
O：138, SEQ ID NO：139, SEQ ID NO：140, SEQ ID N
O：141, SEQ ID NO：142, SEQ ID NO：143, SEQ ID N
O：144, SEQ ID NO：145, SEQ ID NO：146, SEQ ID N
O：147, SEQ ID NO：148, SEQ ID NO：149, SEQ ID N
O：150, SEQ ID NO：151, SEQ ID NO：152, SEQ ID N
O：153, SEQ ID NO：154, SEQ ID NO：155, SEQ ID N
O：156, SEQ ID NO：157, SEQ ID NO：158, SEQ ID N
O：159, SEQ ID NO：160, SEQ ID NO：161, SEQ ID N
O：162, SEQ ID NO：163, SEQ ID NO：164, SEQ ID N
O：165, SEQ ID NO：166, SEQ ID NO：167, SEQ ID N
O：168, SEQ ID NO：169, SEQ ID NO：170, SEQ ID N
O：171, SEQ ID NO：172, SEQ ID NO：173, SEQ ID N
O：174, SEQ ID NO：175, SEQ ID NO：176, SEQ ID N
O：177, SEQ ID NO：178, SEQ ID NO：179, SEQ ID N
O：180, SEQ ID NO：181, SEQ ID NO：182, SEQ ID N
O：183, SEQ ID NO：184, SEQ ID NO：185, SEQ ID N
O：186, SEQ ID NO：187, SEQ ID NO：188, SEQ ID N
O：189, SEQ ID NO：190, SEQ ID NO：191, SEQ ID N
O：192, SEQ ID NO：193, SEQ ID NO：194, SEQ ID N
O：195, SEQ ID NO：196, SEQ ID NO：197, SEQ ID N
O：198, SEQ ID NO：199, SEQ ID NO：200, SEQ ID N
O：201, SEQ ID NO：202, SEQ ID NO：203, SEQ ID N
O：204, SEQ ID NO：205, SEQ ID NO：206, SEQ ID N
O：207, SEQ ID NO：208, SEQ ID NO：209, SEQ ID N
O：210, SEQ ID NO：211, SEQ ID NO：212, SEQ ID N
O：213, SEQ ID NO：214, SEQ ID NO：215, SEQ ID N
O：216, SEQ ID NO：217, SEQ ID NO：218, SEQ ID N
O：219, SEQ ID NO：220, SEQ ID NO：221, SEQ ID N
O：222, SEQ ID NO：223, SEQ ID NO：224, SEQ ID N
O：225, SEQ ID NO：226, SEQ ID NO：227, SEQ ID N
O：228, SEQ ID NO：229, SEQ ID NO：230, SEQ ID N
O：231, SEQ ID NO：232, SEQ ID NO：233, SEQ ID N
O：234, SEQ ID NO：235, SEQ ID NO：236, SEQ ID N
O：237, SEQ ID NO：238, SEQ ID NO：239, SEQ ID N
O：240, SEQ ID NO：241, SEQ ID NO：242, SEQ ID N
O：243, SEQ ID NO：245, SEQ ID NO：246, SEQ ID N
O：247, SEQ ID NO：248, SEQ ID NO：249, SEQ ID N
O：250, SEQ ID NO：251, SEQ ID NO：252, SEQ ID N
O：253, SEQ ID NO：254, SEQ ID NO：255, SEQ ID N
O：256, SEQ ID NO：257, SEQ ID NO：258, SEQ ID N
O：259, SEQ ID NO：260, SEQ ID NO：261, SEQ ID N
O：262, SEQ ID NO：263, SEQ ID NO：264, SEQ ID N
O：265, SEQ ID NO：266, SEQ ID NO：267, SEQ ID N
O：268, SEQ ID NO：269, SEQ ID NO：270, SEQ ID N
O：271, SEQ ID NO：272, SEQ ID NO：273, SEQ ID N
O：274, SEQ ID NO：275, SEQ ID NO：276, SEQ ID N
O：277, SEQ ID NO：278, SEQ ID NO：279, SEQ ID N
O：280, SEQ ID NO：281, SEQ ID NO：282, SEQ ID N
O：283, SEQ ID NO：284, SEQ ID NO：285, SEQ ID N
O：286, SEQ ID NO：287, SEQ ID NO：288, SEQ ID N
O：289, SEQ ID NO：290, SEQ ID NO：291, SEQ ID N
O：292, SEQ ID NO：293, SEQ ID NO：294, SEQ ID N
O：295, SEQ ID NO：296, SEQ ID NO：297, SEQ ID N
O：298, SEQ ID NO：299, SEQ ID NO：300, SEQ ID N
O：301, SEQ ID NO：302, SEQ ID NO：303, SEQ ID N
O：304, SEQ ID NO：305, SEQ ID NO：306, SEQ ID N
O：307, SEQ ID NO：308, SEQ ID NO：309, SEQ ID N
O：310, SEQ ID NO：311, SEQ ID NO：312, SEQ ID N
O：313, SEQ ID NO：314, SEQ ID NO：315, SEQ ID N
O：316, SEQ ID NO：317, SEQ ID NO：318, SEQ ID N
O：319, SEQ ID NO：320, SEQ ID NO：321, SEQ ID N
O：322, SEQ ID NO：323, SEQ ID NO：324, SEQ ID N
O：325, SEQ ID NO：326, SEQ ID NO：327, SEQ ID N
O：328, SEQ ID NO：329, SEQ ID NO：330, SEQ ID N
O：331, SEQ ID NO：332, SEQ ID NO：333, SEQ ID N
O：334, SEQ ID NO：335, SEQ ID NO：336, SEQ ID N
O：338, SEQ ID NO：339, SEQ ID NO：340, SEQ ID N
O：341, SEQ ID NO：342, SEQ ID NO：343, SEQ ID N
O：344, SEQ ID NO：345, SEQ ID NO：346, SEQ ID N
O：347, SEQ ID NO：348, SEQ ID NO：349, SEQ ID N
O：350, SEQ ID NO：351, SEQ ID NO：352, SEQ ID N
O：353, SEQ ID NO：354, SEQ ID NO：355, SEQ ID N
O：356, SEQ ID NO：357, SEQ ID NO：358, SEQ ID N
O：359, SEQ ID NO：360, SEQ ID NO：361, SEQ ID N
O：362, SEQ ID NO：363, SEQ ID NO：364, SEQ ID N
O：365, SEQ ID NO：366, SEQ ID NO：367, SEQ ID N
O：368, SEQ ID NO：369, SEQ ID NO：370, SEQ ID N
O：371, SEQ ID NO：372, SEQ ID NO：373, SEQ ID N
O：374, SEQ ID NO：375, SEQ ID NO：376, SEQ ID N
O：377, SEQ ID NO：378, SEQ ID NO：379, SEQ ID N
O：380, SEQ ID NO：381, SEQ ID NO：382, SEQ ID N
O：383, SEQ ID NO：384, SEQ ID NO：385, SEQ ID N
O：386, SEQ ID NO：387, SEQ ID NO：388, SEQ ID N
O：389, SEQ ID NO：390, SEQ ID NO：391, SEQ ID N
O：392, SEQ ID NO：393, SEQ ID NO：394, SEQ ID N
O：395, SEQ ID NO：396, SEQ ID NO：397, SEQ ID N
O：398, SEQ ID NO：399, SEQ ID NO：400, SEQ ID N
O：401, SEQ ID NO：402, SEQ ID NO：403, SEQ ID N
O：404, SEQ ID NO：405, SEQ ID NO：406, SEQ ID N
O：407, SEQ ID NO：408, SEQ ID NO：409, SEQ ID N
O：411, SEQ ID NO：412, SEQ ID NO：413, SEQ ID N
O：414, SEQ ID NO：415, SEQ ID NO：416, SEQ ID N
O：417, SEQ ID NO：418, SEQ ID NO：419, SEQ ID N
O：420, SEQ ID NO：421, SEQ ID NO：422, SEQ ID N
O：423, SEQ ID NO：424, SEQ ID NO：425, SEQ ID N
O：426, SEQ ID NO：427, SEQ ID NO：428, SEQ ID N
O：429, SEQ ID NO：430, SEQ ID NO：431, SEQ ID N
O：432, SEQ ID NO：433, SEQ ID NO：434, SＥＱ Ｉ
Ｄ ＮＯ：435, SEQ ID NO：436, SEQ ID NO：437, SEQ
ID NO：438, SEQ ID NO：439, SEQ ID NO：440, SEQ I
D NO：441, SEQ ID NO：442, SEQ ID NO：443, SEQ ID
NO：444, SEQ ID NO：445, SEQ ID NO：446, SEQ ID N
O：447, SEQ ID NO：448, SEQ ID NO：449, SEQ ID N
O：450, SEQ ID NO：451, SEQ ID NO：452, SEQ ID N
O：453, SEQ ID NO：454, SEQ ID NO：455, SEQ ID N
O：456, SEQ ID NO：457, SEQ ID NO：458, SEQ ID N
O：459, SEQ ID NO：460, SEQ ID NO：461, SEQ ID N
O：462, SEQ ID NO：463, SEQ ID NO：464, SEQ ID N
O：465, SEQ ID NO：466, SEQ ID NO：467, SEQ ID N
O：468, SEQ ID NO：469, SEQ ID NO：470, SEQ ID N
O：471, SEQ ID NO：472, SEQ ID NO：473, SEQ ID N
O：474, SEQ ID NO：475, SEQ ID NO：476, SEQ ID N
O：477, SEQ ID NO：478, SEQ ID NO：479, SEQ ID N
O：480, SEQ ID NO：481, SEQ ID NO：482, SEQ ID N
O：483, SEQ ID NO：485, SEQ ID NO：486, SEQ ID N
O：487, SEQ ID NO：488, SEQ ID NO：489, SEQ ID N
O：490, SEQ ID NO：491, SEQ ID NO：492, SEQ ID N
O：493, SEQ ID NO：494, SEQ ID NO：495, SEQ ID N
O：496, SEQ ID NO：497, SEQ ID NO：498, SEQ ID N
O：499, SEQ ID NO：500, SEQ ID NO：501, SEQ ID N
O：502, SEQ ID NO：503, SEQ ID NO：504, SEQ ID N
O：505, SEQ ID NO：506, SEQ ID NO：507, SEQ ID N
O：508, SEQ ID NO：509, SEQ ID NO：510, SEQ ID N
O：511, SEQ ID NO：512, SEQ ID NO：513, SEQ ID N
O：514, SEQ ID NO：515, SEQ ID NO：516, SEQ ID N
O：517, SEQ ID NO：518, SEQ ID NO：519, SEQ ID N
O：520, SEQ ID NO：521, SEQ ID NO：522, SEQ ID N
O：523, SEQ ID NO：524, SEQ ID NO：525, SEQ ID N
O：526, SEQ ID NO：527, SEQ ID NO：528, SEQ ID N
O：529, SEQ ID NO：530, SEQ ID NO：531, SEQ ID N
O：532, SEQ ID NO：533, SEQ ID NO：534, SEQ ID N
O：535, SEQ ID NO：536, SEQ ID NO：537, SEQ ID N
O：538, SEQ ID NO：539, SEQ ID NO：540, SEQ ID N
O：541, SEQ ID NO：542, SEQ ID NO：543, SEQ ID N
O：544, SEQ ID NO：545, SEQ ID NO：546, SEQ ID N
O：547, SEQ ID NO：548, SEQ ID NO：549, SEQ ID N
O：550, SEQ ID NO：551, SEQ ID NO：552, SEQ ID N
O：553, SEQ ID NO：555, SEQ ID NO：556, SEQ ID N
O：557, SEQ ID NO：558, SEQ ID NO：559, SEQ ID N
O：560, SEQ ID NO：561, SEQ ID NO：562, SEQ ID N
O：563, SEQ ID NO：564, SEQ ID NO：565, SEQ ID N
O：566, SEQ ID NO：567, SEQ ID NO：568, SEQ ID N
O：569, SEQ ID NO：570, SEQ ID NO：571, SEQ ID N
O：572, SEQ ID NO：573, SEQ ID NO：574, SEQ ID N
O：575, SEQ ID NO：576, SEQ ID NO：577, SEQ ID N
O：578, SEQ ID NO：579, SEQ ID NO：580, SEQ ID N
O：581, SEQ ID NO：582, SEQ ID NO：583, SEQ ID N
O：584, SEQ ID NO：585, SEQ ID NO：586, SEQ ID N
O：587, SEQ ID NO：588, SEQ ID NO：589, SEQ ID N
O：590, SEQ ID NO：591, SEQ ID NO：592, SEQ ID N
O：593, SEQ ID NO：594, SEQ ID NO：595, SEQ ID N
O：596, SEQ ID NO：597, SEQ ID NO：598, SEQ ID N
O：599, SEQ ID NO：600, SEQ ID NO：601, SEQ ID N
O：602, SEQ ID NO：603, SEQ ID NO：604, SEQ ID N
O：605, SEQ ID NO：606, SEQ ID NO：607, SEQ ID N
O：608, SEQ ID NO：609, SEQ ID NO：610, SEQ ID N
O：611, SEQ ID NO：612, SEQ ID NO：613, SEQ ID N
O：614, SEQ ID NO：615, SEQ ID NO：616, SEQ ID N
O：617, SEQ ID NO：618, SEQ ID NO：619, SEQ ID N
O：620, SEQ ID NO：621, SEQ ID NO：622, SEQ ID N
O：623, SEQ ID NO：624, SEQ ID NO：625, SEQ ID N
O：626, SEQ ID NO：627, SEQ ID NO：628, SEQ ID N
O：629, SEQ ID NO：631, SEQ ID NO：632, SEQ ID N
O：633, SEQ ID NO：634, SEQ ID NO：635, SEQ ID N
O：636, SEQ ID NO：637, SEQ ID NO：638, SEQ ID N
O：639, SEQ ID NO：640, SEQ ID NO：641, SEQ ID N
O：642, SEQ ID NO：643, SEQ ID NO：644, SEQ ID N
O：645, SEQ ID NO：646, SEQ ID NO：647, SEQ ID N
O：648, SEQ ID NO：649, SEQ ID NO：650, SEQ ID N
O：651, SEQ ID NO：652, SEQ ID NO：653, SEQ ID N
O：654, SEQ ID NO：655, SEQ ID NO：656, SEQ ID N
O：657, SEQ ID NO：658, SEQ ID NO：659, SEQ ID N
O：660, SEQ ID NO：661, SEQ ID NO：662, SEQ ID N
O：663, SEQ ID NO：664, SEQ ID NO：665, SEQ ID N
O：666, SEQ ID NO：667, SEQ ID NO：668, SEQ ID N
O：669, SEQ ID NO：670, SEQ ID NO：671, SEQ ID N
O：672, SEQ ID NO：673, SEQ ID NO：674, SEQ ID N
O：675, SEQ ID NO：676, SEQ ID NO：677, SEQ ID N
O：678, SEQ ID NO：679, SEQ ID NO：680, SEQ ID N
O：681, SEQ ID NO：682, SEQ ID NO：683, SEQ ID N
O：684, SEQ ID NO：685, SEQ ID NO：686, SEQ ID N
O：687, SEQ ID NO：688, SEQ ID NO：690, SEQ ID N
O：691, SEQ ID NO：692, SEQ ID NO：693, SEQ ID N
O：694, SEQ ID NO：695, SEQ ID NO：696, SEQ ID N
O：697, SEQ ID NO：698, SEQ ID NO：699, SＥＱ Ｉ
Ｄ ＮＯ：700, SEQ ID NO：701, SEQ ID NO：702, SEQ
ID NO：703, SEQ ID NO：704, SEQ ID NO：705, SEQ I
D NO：706, SEQ ID NO：707, SEQ ID NO：708, SEQ ID
NO：709, SEQ ID NO：710, SEQ ID NO：711, SEQ ID N
O：712, SEQ ID NO：713, SEQ ID NO：714, SEQ ID N
O：715, SEQ ID NO：716, SEQ ID NO：717, SEQ ID N
O：718, SEQ ID NO：719, SEQ ID NO：720, SEQ ID N
O：721, SEQ ID NO：722, SEQ ID NO：723, SEQ ID N
O：724, SEQ ID NO：725, SEQ ID NO：726, SEQ ID N
O：727, SEQ ID NO：728, SEQ ID NO：729, SEQ ID N
O：730, SEQ ID NO：731, SEQ ID NO：732, SEQ ID N
O：733, SEQ ID NO：734, SEQ ID NO：735, SEQ ID N
O：736, SEQ ID NO：737, SEQ ID NO：738, SEQ ID N
O：739, SEQ ID NO：740, SEQ ID NO：741, SEQ ID N
O：742, SEQ ID NO：743, SEQ ID NO：744, SEQ ID N
O：745, SEQ ID NO：746, SEQ ID NO：747, SEQ ID N
O：748, SEQ ID NO：749, SEQ ID NO：750, SEQ ID N
O：751, SEQ ID NO：752, SEQ ID NO：753, SEQ ID N
O：754, SEQ ID NO：756, SEQ ID NO：757, SEQ ID N
O：758, SEQ ID NO：759, SEQ ID NO：760, SEQ ID N
O：761, SEQ ID NO：762, SEQ ID NO：763, SEQ ID N
O：764, SEQ ID NO：765, SEQ ID NO：766, SEQ ID N
O：767, SEQ ID NO：768, SEQ ID NO：769, SEQ ID N
O：770, SEQ ID NO：771, SEQ ID NO：772, SEQ ID N
O：773, SEQ ID NO：774, SEQ ID NO：775, SEQ ID N
O：776, SEQ ID NO：777, SEQ ID NO：778, SEQ ID N
O：779, SEQ ID NO：780, SEQ ID NO：781, SEQ ID N
O：782, SEQ ID NO：783, SEQ ID NO：784, SEQ ID N
O：785, SEQ ID NO：786, SEQ ID NO：787, SEQ ID N
O：788, SEQ ID NO：789, SEQ ID NO：790, SEQ ID N
O：791, SEQ ID NO：792, SEQ ID NO：793, SEQ ID N
O：794, SEQ ID NO：795, SEQ ID NO：796, SEQ ID N
O：797, SEQ ID NO：798, SEQ ID NO：799, SEQ ID N
O：800, SEQ ID NO：801, SEQ ID NO：802, SEQ ID N
O：803, SEQ ID NO：804, SEQ ID NO：805, SEQ ID N
O：806, SEQ ID NO：807, SEQ ID NO：808, SEQ ID N
O：809, SEQ ID NO：810, SEQ ID NO：811, SEQ ID N
O：812, SEQ ID NO：813, SEQ ID NO：814, SEQ ID N
O：815, SEQ ID NO：817, SEQ ID NO：818, SEQ ID N
O：819, SEQ ID NO：820, SEQ ID NO：821, SEQ ID N
O：822, SEQ ID NO：823, SEQ ID NO：824, SEQ ID N
O：825, SEQ ID NO：826, SEQ ID NO：827, SEQ ID N
O：828, SEQ ID NO：829, SEQ ID NO：830, SEQ ID N
O：831, SEQ ID NO：832, SEQ ID NO：833, SEQ ID N
O：834, SEQ ID NO：835, SEQ ID NO：836, SEQ ID N
O：837, SEQ ID NO：838, SEQ ID NO：839, SEQ ID N
O：840, SEQ ID NO：841, SEQ ID NO：842, SEQ ID N
O：843, SEQ ID NO：844, SEQ ID NO：845, SEQ ID N
O：846, SEQ ID NO：847, SEQ ID NO：848, SEQ ID N
O：849, SEQ ID NO：850, SEQ ID NO：851, SEQ ID N
O：852, SEQ ID NO：853, SEQ ID NO：854, SEQ ID N
O：855, SEQ ID NO：856, SEQ ID NO：857, SEQ ID N
O：858, SEQ ID NO：859, SEQ ID NO：860, SEQ ID N
O：861, SEQ ID NO：862, SEQ ID NO：863, SEQ ID N
O：864, SEQ ID NO：865, SEQ ID NO：866, SEQ ID N
O：867, SEQ ID NO：868, SEQ ID NO：869, SEQ ID N
O：870, SEQ ID NO：871, SEQ ID NO：872, SEQ ID N
O：873, SEQ ID NO：874, SEQ ID NO：875, SEQ ID N
O：877, SEQ ID NO：878, SEQ ID NO：879, SEQ ID N
O：880, SEQ ID NO：881, SEQ ID NO：882, SEQ ID N
O：883, SEQ ID NO：884, SEQ ID NO：885, SEQ ID N
O：886, SEQ ID NO：887, SEQ ID NO：888, SEQ ID N
O：889, SEQ ID NO：890, SEQ ID NO：891, SEQ ID N
O：892, SEQ ID NO：893, SEQ ID NO：894, SEQ ID N
O：895, SEQ ID NO：896, SEQ ID NO：897, SEQ ID N
O：898, SEQ ID NO：899, SEQ ID NO：900, SEQ ID N
O：901, SEQ ID NO：902, SEQ ID NO：903, SEQ ID N
O：904, SEQ ID NO：905, SEQ ID NO：906, SEQ ID N
O：907, SEQ ID NO：908, SEQ ID NO：909, SEQ ID N
O：910, SEQ ID NO：911, SEQ ID NO：912, SEQ ID N
O：913, SEQ ID NO：914, SEQ ID NO：915, SEQ ID N
O：916, SEQ ID NO：917, SEQ ID NO：918, SEQ ID N
O：919, SEQ ID NO：920, SEQ ID NO：921, SEQ ID N
O：922, SEQ ID NO：923, SEQ ID NO：924, SEQ ID N
O：925, SEQ ID NO：926, SEQ ID NO：928, SEQ ID N
O：929, SEQ ID NO：930, SEQ ID NO：931, SEQ ID N
O：932, SEQ ID NO：933, SEQ ID NO：934, SEQ ID N
O：935, SEQ ID NO：936, SEQ ID NO：937, SEQ ID N
O：938, SEQ ID NO：939, SEQ ID NO：940, SEQ ID N
O：941, SEQ ID NO：942, SEQ ID NO：943, SEQ ID N
O：944, SEQ ID NO：945, SEQ ID NO：946, SEQ ID N
O：947, SEQ ID NO：948, SEQ ID NO：949, SEQ ID N
O：950, SEQ ID NO：951, SEQ ID NO：952, SEQ ID N
O：953, SEQ ID NO：954, SEQ ID NO：955, SEQ ID N
O：956, SEQ ID NO：957, SEQ ID NO：958, SEQ ID N
O：959, SEQ ID NO：960, SEQ ID NO：961, SEQ ID N
O：962, SEQ ID NO：963, SEQ ID NO：964, SＥＱ Ｉ
Ｄ ＮＯ：965, SEQ ID NO：966, SEQ ID NO：967, SEQ
ID NO：968, SEQ ID NO：969, SEQ ID NO：970, SEQ I
D NO：971, SEQ ID NO：972, SEQ ID NO：973, SEQ ID
NO：974, SEQ ID NO：975, SEQ ID NO：976, SEQ ID N
O：977, SEQ ID NO：979, SEQ ID NO：980, SEQ ID N
O：981, SEQ ID NO：982, SEQ ID NO：983, SEQ ID N
O：984, SEQ ID NO：985, SEQ ID NO：986, SEQ ID N
O：987, SEQ ID NO：988, SEQ ID NO：989, SEQ ID N
O：990, SEQ ID NO：991, SEQ ID NO：992, SEQ ID N
O：993, SEQ ID NO：994, SEQ ID NO：995, SEQ ID N
O：996, SEQ ID NO：997, SEQ ID NO：998, SEQ ID N
O：999, SEQ ID NO：1000, SEQ ID NO：1001,SEQ ID N
O：1002, SEQ ID NO：1003, SEQ ID NO：1004, SEQ ID
NO：1005, SEQID NO：1006, SEQ ID NO：1007, SEQ ID
NO：1008, SEQ ID NO：1009, SEQ IDNO：1010, SEQ ID
NO：1011, SEQ ID NO：1012, SEQ ID NO：1014, SEQ ID
NO：1015, SEQ ID NO：1016, SEQ ID NO：1017, SEQ I
D NO：1018, SEQ ID NO：1019, SEQ ID NO：1020, SEQ
ID NO：1021, SEQ ID NO：1022, SEQ ID NO：1023, SEQ
ID NO：1024, SEQ ID NO：1025, SEQ ID NO：1026, SE
Q ID NO：1027, SEQ IDNO：1028, SEQ ID NO：1030, SE
Q ID NO：1031, SEQ ID NO：1032, SEQ ID NO：1033, S
EQ ID NO：1034, SEQ ID NO：1035, SEQ ID NO：1036,
SEQ ID NO：1037, SEQ ID NO：1038, SEQ ID NO：1039,
SEQ ID NO：1040, SEQ ID NO：1041,SEQ ID NO：1042,
SEQ ID NO：1043, SEQ ID NO：1044, SEQ ID NO：104
5, SEQID NO：1046, SEQ ID NO：1047, SEQ ID NO：104
8, SEQ ID NO：1049, SEQ ID NO：1050, SEQ ID NO：10
51, SEQ ID NO：1052, SEQ ID NO：1053, SEQ ID NO：1
054, SEQ ID NO：1056, SEQ ID NO：1057, SEQ ID NO：
1058, SEQ ID NO：1059,SEQ ID NO：1061, SEQ ID NO：
1062, SEQ ID NO：1063, SEQ ID NO：1064, SEQID NO：
1065, SEQ ID NO：1066, SEQ ID NO：1067, SEQ ID N
O：1068, SEQ IDNO：1069, SEQ ID NO：1070, SEQ ID N
O：1071, SEQ ID NO：1072, SEQ ID NO：1073, SEQ ID
NO：1074, SEQ ID NO：1075, SEQ ID NO：1076, SEQ ID
NO：1077, SEQ ID NO：1078, SEQ ID NO：1079, SEQ I
D NO：1080, SEQ ID NO：1081, SEQ ID NO：1082, SEQ
ID NO：1083, SEQ ID NO：1084, SEQ ID NO：1085, SEQ
IDNO：1086, SEQ ID NO：1087, SEQ ID NO：1088, SEQ
ID NO：1089, SEQ ID NO：1090, SEQ ID NO：1091, SE
Q ID NO：1092, SEQ ID NO：1094, SEQ ID NO：1095, S
EQ ID NO：1096, SEQ ID NO：1097, SEQ ID NO：1098,
SEQ ID NO：1099,SEQ ID NO：1100, SEQ ID NO：1101,
SEQ ID NO：1102, SEQ ID NO：1103, SEQID NO：1104,
SEQ ID NO：1105, SEQ ID NO：1106, SEQ ID NO：1107,
SEQ ID NO：1108, SEQ ID NO：1109, SEQ ID NO：111
0, SEQ ID NO：1111, SEQ ID NO：1112, SEQ ID NO：11
13, SEQ ID NO：1114, SEQ ID NO：1115, SEQ ID NO：1
116,SEQ ID NO：1117, SEQ ID NO：1118, SEQ ID NO：1
119, SEQ ID NO：1120, SEQID NO：1121, SEQ ID NO：1
122, SEQ ID NO：1123, SEQ ID NO：1124, SEQ IDNO：1
125, SEQ ID NO：1126, SEQ ID NO：1127, SEQ ID NO：
1129, SEQ ID NO：1130, SEQ ID NO：1131, SEQ ID N
O：1132, SEQ ID NO：1133, SEQ ID NO：1134, SEQ ID
NO：1135, SEQ ID NO：1136, SEQ ID NO：1137, SEQ ID
NO：1138, SEQ ID NO：1139, SEQ ID NO：1140, SEQ I
D NO：1141, SEQ ID NO：1142, SEQ IDNO：1143, SEQ I
D NO：1144, SEQ ID NO：1145, SEQ ID NO：1146, SEQ
ID NO：1147, SEQ ID NO：1148, SEQ ID NO：1149, SEQ
ID NO：1150, SEQ ID NO：1151, SEQ ID NO：1152, SE
Q ID NO：1153, SEQ ID NO：1154, SEQ ID NO：1155,SE
Q ID NO：1156, SEQ ID NO：1158, SEQ ID NO：1159, S
EQ ID NO：1160, SEQID NO：1161, SEQ ID NO：1162, S
EQ ID NO：1163, SEQ ID NO：1164, SEQ ID NO：1165,
SEQ ID NO：1166, SEQ ID NO：1167, SEQ ID NO：1168,
SEQ ID NO：1169, SEQ ID NO：1170, SEQ ID NO：117
1, SEQ ID NO：1172, SEQ ID NO：1173,SEQ ID NO：117
4, SEQ ID NO：1175, SEQ ID NO：1176, SEQ ID NO：11
77, SEQID NO：1178, SEQ ID NO：1179, SEQ ID NO：11
80, SEQ ID NO：1181, SEQ IDNO：1182, SEQ ID NO：11
83, SEQ ID NO：1184, SEQ ID NO：1185, SEQ ID NO：1
186, SEQ ID NO：1187, SEQ ID NO：1188, SEQ ID NO：
1189, SEQ ID NO：1190, SEQ ID NO：1192, SEQ ID N
O：1193, SEQ ID NO：1194, SEQ ID NO：1195, SEQ ID
NO：1196, SEQ ID NO：1197, SEQ ID NO：1198, SEQ ID
NO：1199, SEQ IDNO：1200, SEQ ID NO：1201, SEQ ID
NO：1202, SEQ ID NO：1203, SEQ ID NO：1204, SEQ I
D NO：1205, SEQ ID NO：1206, SEQ ID NO：1207, SEQ
ID NO：1208, SEQ ID NO：1209, SEQ ID NO：1210, SEQ
ID NO：1211, SEQ ID NO：1213,SEQ ID NO：1214, SEQ
ID NO：1215, SEQ ID NO：1216, SEQ ID NO：1217, SE
QID NO：1218, SEQ ID NO：1219, SEQ ID NO：1220, SE
Q ID NO：1221, SEQ ID NＯ：1222, SEQ ID NO：1223,
SEQ ID NO：1224, SEQ ID NO：1225, SEQ ID NO：1226,
SEQ ID NO：1227, SEQ ID NO：1228, SEQ ID NO：122
9, SEQ ID NO：1230,SEQ ID NO：1231, SEQ ID NO：123
2, SEQ ID NO：1233, SEQ ID NO：1234, SEQID NO：123
5, SEQ ID NO：1236, SEQ ID NO：1237, SEQ ID NO：12
38, SEQ IDNO：1239, SEQ ID NO：1241, SEQ ID NO：12
42, SEQ ID NO：1243, SEQ ID NO：1244, SEQ ID NO：1
245, SEQ ID NO：1246, SEQ ID NO：1247, SEQ ID NO：
1248, SEQ ID NO：1249, SEQ ID NO：1250, SEQ ID N
O：1251, SEQ ID NO：1252, SEQ ID NO：1253, SEQ ID
NO：1254, SEQ ID NO：1255, SEQ ID NO：1256, SEQ ID
NO：1257, SEQ ID NO：1259, SEQ ID NO：1260, SEQ ID
NO：1261, SEQ ID NO：1262, SEQ ID NO：1263, SEQ I
D NO：1264, SEQ ID NO：1265, SEQ ID NO：1266, SEQ
ID NO：1267, SEQ ID NO：1268, SEQ ID NO：1269, SEQ
ID NO：1270,SEQ ID NO：1271, SEQ ID NO：1272, SEQ
ID NO：1273, SEQ ID NO：1275, SEQID NO：1276, SEQ
ID NO：1277, SEQ ID NO：1278, SEQ ID NO：1279, SE
Q ID NO：1280, SEQ ID NO：1281, SEQ ID NO：1282, S
EQ ID NO：1283, SEQ ID NO：1284, SEQ ID NO：1285,
SEQ ID NO：1286, SEQ ID NO：1287, SEQ ID NO：1289,
SEQ ID NO：1290, SEQ ID NO：1291, SEQ ID NO：1292,
SEQ ID NO：1293, SEQID NO：1294, SEQ ID NO：1295,
SEQ ID NO：1296, SEQ ID NO：1297, SEQ IDNO：1298,
SEQ ID NO：1299, SEQ ID NO：1300, SEQ ID NO：130
1, SEQ ID NO：1303, SEQ ID NO：1304, SEQ ID NO：13
05, SEQ ID NO：1306, SEQ ID NO：1307, SEQ ID NO：1
308, SEQ ID NO：1310, SEQ ID NO：1311, SEQ ID NO：
1312, SEQ ID NO：1313, SEQ ID NO：1314, SEQ ID N
O：1315, SEQ ID NO：1316, SEQ IDNO：1317, SEQ ID N
O：1318, SEQ ID NO：1319, SEQ ID NO：1320, SEQ ID
NO：1322, SEQ ID NO：1323, SEQ ID NO：1324, SEQ ID
NO：1325, SEQ ID NO：1326, SEQ ID NO：1327, SEQ I
D NO：1328, SEQ ID NO：1330, SEQ ID NO：1331,SEQ I
D NO：1332, SEQ ID NO：1333, SEQ ID NO：1334, SEQ
ID NO：1335, SEQID NO：1336, SEQ ID NO：1337, SEQ
ID NO：1339, SEQ ID NO：1340, SEQ ID NO：1341, SEQ
ID NO：1342, SEQ ID NO：1343, SEQ ID NO：1344, SE
Q ID NO：1345, SEQ ID NO：1346, SEQ ID NO：1347, S
EQ ID NO：1349, SEQ ID NO：1350,SEQ ID NO：1351, S
EQ ID NO：1352, SEQ ID NO：1353, SEQ ID NO：1354,
SEQID NO：1355, SEQ ID NO：1356, SEQ ID NO：1357,
SEQ ID NO：1358, SEQ IDNO：1360, SEQ ID NO：1361,
SEQ ID NO：1362, SEQ ID NO：1363, SEQ ID NO：1364,
SEQ ID NO：1365, SEQ ID NO：1367, SEQ ID NO：136
8, SEQ ID NO：1369, SEQ ID NO：1370, SEQ ID NO：13
71, SEQ ID NO：1375, SEQ ID NO：1376, SEQ ID NO：1
377, SEQ ID NO：1378, SEQ ID NO：1379, SEQ ID NO：
1381, SEQ IDNO：1382, SEQ ID NO：1383, SEQ ID NO：
1384, SEQ ID NO：1385, SEQ ID NO：1387, SEQ ID N
O：1388, SEQ ID NO：1389, SEQ ID NO：1390, SEQ ID
NO：1391, SEQ ID NO：1392, SEQ ID NO：1393, SEQ ID
NO：1395, SEQ ID NO：1396,SEQ ID NO：1397, SEQ ID
NO：1398, SEQ ID NO：1399, SEQ ID NO：1400, SEQID
NO：1402, SEQ ID NO：1403, SEQ ID NO：1404, SEQ I
D NO：1405, SEQ ID NO：1406, SEQ ID NO：1407, SEQ
ID NO：1409, SEQ ID NO：1410, SEQ ID NO：1412, SEQ
ID NO：1413, SEQ ID NO：1414, SEQ ID NO：1415, SE
Q ID NO：1416,SEQ ID NO：1417, SEQ ID NO：1419, SE
Q ID NO：1420, SEQ ID NO：1421, SEQID NO：1422, SE
Q ID NO：1423, SEQ ID NO：1424, SEQ ID NO：1425, S
EQ IDNO：1427, SEQ ID NO：1428, SEQ ID NO：1429, S
EQ ID NO：1430, SEQ ID NO：1431, SEQ ID NO：1432,
SEQ ID NO：1433, SEQ ID NO：1434, SEQ ID NO：1435,
SEQ ID NO：1437, SEQ ID NO：1438, SEQ ID NO：143
9, SEQ ID NO：1440, SEQ ID NO：1441, SEQ ID NO：14
42, SEQ ID NO：1444, SEQ ID NO：1445, SEQ IDNO：14
46, SEQ ID NO：1447, SEQ ID NO：1448, SEQ ID NO：1
449, SEQ ID NO：1451, SEQ ID NO：1452, SEQ ID NO：
1453, SEQ ID NO：1454, SEQ ID NO：1455, SEQ ID N
O：1456, SEQ ID NO：1458, SEQ ID NO：1459, SEQ ID
NO：1461,SEQ ID NO：1462, SEQ ID NO：1463, SEQ ID
NO：1464, SEQ ID NO：1465, SEQID NO：1466, SEQ ID
NO：1468, SEQ ID NO：1469, SEQ ID NO：1470, SEQ ID
NO：1472, SEQ ID NO：1474, SEQ ID NO：1475, SEQ I
D NO：1476, SEQ ID NO：1477, SEQ ID NO：1479, SEQ
ID NO：1480, SEQ ID NO：1481, SEQ ID NO：1482,SEQ
ID NO：1483, SEQ ID NO：1484, SEQ ID NO：1485, SEQ
ID NO：1486, SEQID NO：1488, SEQ ID NO：1490, SEQ
ID NO：1491, SEQ ID NO：1492, SEQ IDNO：1493, SEQ
ID NO：1495, SEQ ID NO：1496, SEQ ID NO：1497, SE
Q ID NO：1498, SEQ ID NO：1500, SEQ ID NO：1502, S
EQ ID NO：1503, SEQ ID NO：1504， ＳＥＱ ＩＤ
ＮＯ：1505, SEQ ID NO：1507, SEQ ID NO：1509, SEQ
ID NO：1512, SEQ ID NO：1513, SEQ ID NO：1514, SEQ
ID NO：1515, SEQ ID NO：1517, SEQ IDNO：1518, SEQ
ID NO：1519, SEQ ID NO：1521, SEQ ID NO：1522, SE
Q ID NO：1523, SEQ ID NO：1524, SEQ ID NO：1525, S
EQ ID NO：1527, SEQ ID NO：1528, SEQ ID NO：1529,
SEQ ID NO：1530, SEQ ID NO：1531, SEQ ID NO：1533,
SEQ ID NO：1534, SEQ ID NO：1535, SEQ ID NO：1536,
SEQ ID NO：1538, SEQID NO：1539, SEQ ID NO：1541,
SEQ ID NO：1542, SEQ ID NO：1543, SEQ ID NO：154
4, SEQ ID NO：1546, SEQ ID NO：1548, SEQ ID NO：15
50, SEQ ID NO：1552, SEQ ID NO：1554, SEQ ID NO：1
556, SEQ ID NO：1557, SEQ ID NO：1559,SEQ ID NO：1
560, SEQ ID NO：1561, SEQ ID NO：1562, SEQ ID NO：
1564, SEQID NO：1565, SEQ ID NO：1567, SEQ ID NO：
1568, SEQ ID NO：1570, SEQ IDNO：1572, SEQ ID NO：
1573, SEQ ID NO：1574, SEQ ID NO：1575, SEQ ID N
O：1577, SEQ ID NO：1578, SEQ ID NO：1579, SEQ ID
NO：1581, SEQ ID NO：1582, SEQ ID NO：1583, SEQ ID
NO：1585, SEQ ID NO：1586, SEQ ID NO：1588, SEQ I
D NO：1589, SEQ ID NO：1590, SEQ ID NO：1592, SEQ
ID NO：1593, SEQ IDNO：1595, SEQ ID NO：1597, SEQ
ID NO：1598, SEQ ID NO：1600, SEQ ID NO：1602, SEQ
ID NO：1606, SEQ ID NO：1608, SEQ ID NO：1609, SE
Q ID NO：1610, SEQ ID NO：1611, SEQ ID NO：1613, S
EQ ID NO：1614, SEQ ID NO：1616,SEQ ID NO：1618, S
EQ ID NO：1620, SEQ ID NO：1621, SEQ ID NO：1623,
SEQID NO：1625, SEQ ID NO：1628, SEQ ID NO：1630,
SEQ ID NO：1631, SEQ ID NO：1633, SEQ ID NO：1634,
SEQ ID NO：1638, SEQ ID NO：1641, SEQ ID NO：164
2, SEQ ID NO：1644, SEQ ID NO：1645, SEQ ID NO：16
47, SEQ ID NO：1648,SEQ ID NO：1650, SEQ ID NO：16
51, SEQ ID NO：1653, SEQ ID NO：1654, SEQID NO：16
56, SEQ ID NO：1657, SEQ ID NO：1659, SEQ ID NO：1
661, SEQ IDNO：1663, SEQ ID NO：1665, SEQ ID NO：1
667, SEQ ID NO：1671, SEQ ID NO：1674, SEQ ID NO：
1676, SEQ ID NO：1678, SEQ ID NO：1679, SEQ ID N
O：1681, SEQ ID NO：1684, SEQ ID NO：1686, SEQ ID
NO：1687, SEQ ID NO：1689, SEQ ID NO：1692, SEQ ID
NO：1693, SEQ ID NO：1695, SEQ ID NO：1697, SEQ I
DNO：1698, SEQ ID NO：1702, およびSEQ ID NO：1703
からなる群から選択されるアミノ酸配列もしくはその断
片、または（ｂ）（ａ）のアミノ酸配列において、数個
のアミノ酸が欠失、置換または付加されたアミノ酸配列
からなるポリペプチドをコードするポリヌクレオチド配
列を有することを特徴とする核酸分子に関する。

【００１３】他の態様において、本発明は腸管出血性病
原性大腸菌Ｏ１５７：Ｈ７に特異的なポリペプチドに関
する。好ましい態様において、本発明は、（ａ）SEQ ID
NO：2, SEQ ID NO：3, SEQ ID NO：4, SEQ ID NO：5,
SEQ ID NO：6, SEQ ID NO：7, SEQ ID NO：8, SEQ ID N
O：9, SEQ ID NO：10, SEQ ID NO：11, SEQ ID NO：12,
SEQ ID NO：13, SEQ ID NO：14, SEQ ID NO：15, SEQ
IDNO：16, SEQ ID NO：17, SEQ ID NO：18, SEQ ID N
O：19, SEQ ID NO：20, SEQID NO：21, SEQ ID NO：22,
SEQ ID NO：23, SEQ ID NO：24, SEQ ID NO：25,SEQ I
D NO：26, SEQ ID NO：27, SEQ ID NO：28, SEQ ID N
O：29, SEQ ID NO：30, SEQ ID NO：31, SEQ ID NO：3
2, SEQ ID NO：33, SEQ ID NO：34, SEQ ID NO：35, SE
Q ID NO：36, SEQ ID NO：37, SEQ ID NO：38, SEQ ID
NO：39, SEQ IDNO：40, SEQ ID NO：41, SEQ ID NO：4
2, SEQ ID NO：43, SEQ ID NO：44, SEQID NO：45, SEQ
ID NO：46, SEQ ID NO：47, SEQ ID NO：48, SEQ ID N
O：49,SEQ ID NO：50, SEQ ID NO：51, SEQ ID NO：52,
SEQ ID NO：53, SEQ ID NO：54, SEQ ID NO：55, SEQ
ID NO：56, SEQ ID NO：57, SEQ ID NO：58, SEQ ID N
O：59, SEQ ID NO：60, SEQ ID NO：61, SEQ ID NO：6
2, SEQ ID NO：63, SEQ IDNO：64, SEQ ID NO：65, SEQ
ID NO：66, SEQ ID NO：67, SEQ ID NO：68, SEQID N
O：69, SEQ ID NO：70, SEQ ID NO：71, SEQ ID NO：7
2, SEQ ID NO：73,SEQ ID NO：74, SEQ ID NO：75, SEQ
ID NO：76, SEQ ID NO：77, SEQ ID NO：78, SEQ ID N
O：79, SEQ ID NO：80, SEQ ID NO：81, SEQ ID NO：8
2, SEQ ID NO：83, SEQ ID NO：84, SEQ ID NO：85, SE
Q ID NO：86, SEQ ID NO：87, SEQ IDNO：88, SEQ ID N
O：89, SEQ ID NO：90, SEQ ID NO：91, SEQ ID NO：9
2, SEQID NO：93, SEQ ID NO：94, SEQ ID NO：95, SEQ
ID NO：96, SEQ ID NO：97,SEQ ID NO：98, SEQ ID N
O：99, SEQ ID NO：100, SEQ ID NO：101, SEQ ID NO：
102, SEQ ID NO：103, SEQ ID NO：104, SEQ ID NO：10
5, SEQ ID NO：106, SEQ ID NO：107, SEQ ID NO：108,
SEQ ID NO：109, SEQ ID NO：110, SEQ ID NO：111, S
EQ ID NO：112, SEQ ID NO：113, SEQ ID NO：114, SEQ
ID NO：115, SEQ ID NO：116, SEQ ID NO：117, SEQ I
D NO：118, SEQ ID NO：119, SEQ ID NO：120, SEQ ID
NO：121, SEQ ID NO：122, SEQ ID NO：123, SEQ ID N
O：124, SEQ ID NO：125, SEQ ID NO：126, SEQ ID N
O：127, SEQ ID NO：128, SEQ ID NO：129, SEQ ID N
O：130, SEQ ID NO：131, SEQ ID NO：133, SEQ ID N
O：134, SEQ ID NO：135, SEQ ID NO：136, SEQ ID N
O：137, SEQ ID NO：138, SEQ ID NO：139, SEQ ID N
O：140, SEQ ID NO：141, SEQ ID NO：142, SEQ ID N
O：143, SEQ ID NO：144, SEQ ID NO：145, SEQ ID N
O：146, SEQ ID NO：147, SEQ ID NO：148, SEQ ID N
O：149, SEQ ID NO：150, SEQ ID NO：151, SEQ ID N
O：152, SEQ ID NO：153, SEQ ID NO：154, SEQ ID N
O：155, SEQ ID NO：156, SEQ ID NO：157, SEQ ID N
O：158, SEQ ID NO：159, SEQ ID NO：160, SEQ ID N
O：161, SEQ ID NO：162, SEQ ID NO：163, SEQ ID N
O：164, SEQ ID NO：165, SEQ ID NO：166, SEQ ID N
O：167, SEQ ID NO：168, SEQ ID NO：169, SEQ ID N
O：170, SEQ ID NO：171, SEQ ID NO：172, SEQ ID N
O：173, SEQ ID NO：174, SEQ ID NO：175, SEQ ID N
O：176, SEQ ID NO：177, SEQ ID NO：178, SEQ ID N
O：179, SEQ ID NO：180, SEQ ID NO：181, SEQ ID N
O：182, SEQ ID NO：183, SEQ ID NO：184, SEQ ID N
O：185, SEQ ID NO：186, SEQ ID NO：187, SEQ ID N
O：188, SEQ ID NO：189, SEQ ID NO：190, SEQ ID N
O：191, SEQ ID NO：192, SEQ ID NO：193, SEQ ID N
O：194, SEQ ID NO：195, SEQ ID NO：196, SEQ ID N
O：197, SEQ ID NO：198, SEQ ID NO：199, SEQ ID N
O：200, SEQ ID NO：201, SEQ ID NO：202, SEQ ID N
O：203, SEQ ID NO：204, SEQ ID NO：205, SEQ ID N
O：206, SEQ ID NO：207, SEQ ID NO：208, SEQ ID N
O：209, SEQ ID NO：210, SEQ ID NO：211, SEQ ID N
O：212, SEQ ID NO：213, SEQ ID NO：214, SEQ ID N
O：215, SEQ ID NO：216, SEQ ID NO：217, SEQ ID N
O：218, SEQ ID NO：219, SEQ ID NO：220, SEQ ID N
O：221, SEQ ID NO：222, SEQ ID NO：223, SEQ ID N
O：224, SEQ ID NO：225, SEQ ID NO：226, SEQ ID N
O：227, SEQ ID NO：228, SEQ ID NO：229, SEQ ID N
O：230, SEQ ID NO：231, SEQ ID NO：232, SEQ ID N
O：233, SＥＱ ＩＤ ＮＯ：234, SEQ ID NO：235, SE
Q ID NO：236, SEQ ID NO：237, SEQ ID NO：238, SEQ
ID NO：239, SEQ ID NO：240, SEQ ID NO：241, SEQ ID
NO：242, SEQ ID NO：243, SEQ ID NO：245, SEQ ID N
O：246, SEQ ID NO：247, SEQ ID NO：248, SEQ ID N
O：249, SEQ ID NO：250, SEQ ID NO：251, SEQ ID N
O：252, SEQ ID NO：253, SEQ ID NO：254, SEQ ID N
O：255, SEQ ID NO：256, SEQ ID NO：257, SEQ ID N
O：258, SEQ ID NO：259, SEQ ID NO：260, SEQ ID N
O：261, SEQ ID NO：262, SEQ ID NO：263, SEQ ID N
O：264, SEQ ID NO：265, SEQ ID NO：266, SEQ ID N
O：267, SEQ ID NO：268, SEQ ID NO：269, SEQ ID N
O：270, SEQ ID NO：271, SEQ ID NO：272, SEQ ID N
O：273, SEQ ID NO：274, SEQ ID NO：275, SEQ ID N
O：276, SEQ ID NO：277, SEQ ID NO：278, SEQ ID N
O：279, SEQ ID NO：280, SEQ ID NO：281, SEQ ID N
O：282, SEQ ID NO：283, SEQ ID NO：284, SEQ ID N
O：285, SEQ ID NO：286, SEQ ID NO：287, SEQ ID N
O：288, SEQ ID NO：289, SEQ ID NO：290, SEQ ID N
O：291, SEQ ID NO：292, SEQ ID NO：293, SEQ ID N
O：294, SEQ ID NO：295, SEQ ID NO：296, SEQ ID N
O：297, SEQ ID NO：298, SEQ ID NO：299, SEQ ID N
O：300, SEQ ID NO：301, SEQ ID NO：302, SEQ ID N
O：303, SEQ ID NO：304, SEQ ID NO：305, SEQ ID N
O：306, SEQ ID NO：307, SEQ ID NO：308, SEQ ID N
O：309, SEQ ID NO：310, SEQ ID NO：311, SEQ ID N
O：312, SEQ ID NO：313, SEQ ID NO：314, SEQ ID N
O：315, SEQ ID NO：316, SEQ ID NO：317, SEQ ID N
O：318, SEQ ID NO：319, SEQ ID NO：320, SEQ ID N
O：321, SEQ ID NO：322, SEQ ID NO：323, SEQ ID N
O：324, SEQ ID NO：325, SEQ ID NO：326, SEQ ID N
O：327, SEQ ID NO：328, SEQ ID NO：329, SEQ ID N
O：330, SEQ ID NO：331, SEQ ID NO：332, SEQ ID N
O：333, SEQ ID NO：334, SEQ ID NO：335, SEQ ID N
O：336, SEQ ID NO：338, SEQ ID NO：339, SEQ ID N
O：340, SEQ ID NO：341, SEQ ID NO：342, SEQ ID N
O：343, SEQ ID NO：344, SEQ ID NO：345, SEQ ID N
O：346, SEQ ID NO：347, SEQ ID NO：348, SEQ ID N
O：349, SEQ ID NO：350, SEQ ID NO：351, SEQ ID N
O：352, SEQ ID NO：353, SEQ ID NO：354, SEQ ID N
O：355, SEQ ID NO：356, SEQ ID NO：357, SEQ ID N
O：358, SEQ ID NO：359, SEQ ID NO：360, SEQ ID N
O：361, SEQ ID NO：362, SEQ ID NO：363, SEQ ID N
O：364, SEQ ID NO：365, SEQ ID NO：366, SEQ ID N
O：367, SEQ ID NO：368, SEQ ID NO：369, SEQ ID N
O：370, SEQ ID NO：371, SEQ ID NO：372, SEQ ID N
O：373, SEQ ID NO：374, SEQ ID NO：375, SEQ ID N
O：376, SEQ ID NO：377, SEQ ID NO：378, SEQ ID N
O：379, SEQ ID NO：380, SEQ ID NO：381, SEQ ID N
O：382, SEQ ID NO：383, SEQ ID NO：384, SEQ ID N
O：385, SEQ ID NO：386, SEQ ID NO：387, SEQ ID N
O：388, SEQ ID NO：389, SEQ ID NO：390, SEQ ID N
O：391, SEQ ID NO：392, SEQ ID NO：393, SEQ ID N
O：394, SEQ ID NO：395, SEQ ID NO：396, SEQ ID N
O：397, SEQ ID NO：398, SEQ ID NO：399, SEQ ID N
O：400, SEQ ID NO：401, SEQ ID NO：402, SEQ ID N
O：403, SEQ ID NO：404, SEQ ID NO：405, SEQ ID N
O：406, SEQ ID NO：407, SEQ ID NO：408, SEQ ID N
O：409, SEQ ID NO：411, SEQ ID NO：412, SEQ ID N
O：413, SEQ ID NO：414, SEQ ID NO：415, SEQ ID N
O：416, SEQ ID NO：417, SEQ ID NO：418, SEQ ID N
O：419, SEQ ID NO：420, SEQ ID NO：421, SEQ ID N
O：422, SEQ ID NO：423, SEQ ID NO：424, SEQ ID N
O：425, SEQ ID NO：426, SEQ ID NO：427, SEQ ID N
O：428, SEQ ID NO：429, SEQ ID NO：430, SEQ ID N
O：431, SEQ ID NO：432, SEQ ID NO：433, SEQ ID N
O：434, SEQ ID NO：435, SEQ ID NO：436, SEQ ID N
O：437, SEQ ID NO：438, SEQ ID NO：439, SEQ ID N
O：440, SEQ ID NO：441, SEQ ID NO：442, SEQ ID N
O：443, SEQ ID NO：444, SEQ ID NO：445, SEQ ID N
O：446, SEQ ID NO：447, SEQ ID NO：448, SEQ ID N
O：449, SEQ ID NO：450, SEQ ID NO：451, SEQ ID N
O：452, SEQ ID NO：453, SEQ ID NO：454, SEQ ID N
O：455, SEQ ID NO：456, SEQ ID NO：457, SEQ ID N
O：458, SEQ ID NO：459, SEQ ID NO：460, SEQ ID N
O：461, SEQ ID NO：462, SEQ ID NO：463, SEQ ID N
O：464, SEQ ID NO：465, SEQ ID NO：466, SEQ ID N
O：467, SEQ ID NO：468, SEQ ID NO：469, SEQ ID N
O：470, SEQ ID NO：471, SEQ ID NO：472, SEQ ID N
O：473, SEQ ID NO：474, SEQ ID NO：475, SEQ ID N
O：476, SEQ ID NO：477, SEQ ID NO：478, SEQ ID N
O：479, SEQ ID NO：480, SEQ ID NO：481, SEQ ID N
O：482, SEQ ID NO：483, SEQ ID NO：485, SEQ ID N
O：486, SEQ ID NO：487, SEQ ID NO：488, SEQ ID N
O：489, SEQ ID NO：490, SEQ ID NO：491, SEQ ID N
O：492, SEQ ID NO：493, SEQ ID NO：494, SEQ ID N
O：495, SEQ ID NO：496, SEQ ID NO：497, SEQ ID N
O：498, SＥＱ ＩＤ ＮＯ：499, SEQ ID NO：500, SE
Q ID NO：501, SEQ ID NO：502, SEQ ID NO：503, SEQ
ID NO：504, SEQ ID NO：505, SEQ ID NO：506, SEQ ID
NO：507, SEQ ID NO：508, SEQ ID NO：509, SEQ ID N
O：510, SEQ ID NO：511, SEQ ID NO：512, SEQ ID N
O：513, SEQ ID NO：514, SEQ ID NO：515, SEQ ID N
O：516, SEQ ID NO：517, SEQ ID NO：518, SEQ ID N
O：519, SEQ ID NO：520, SEQ ID NO：521, SEQ ID N
O：522, SEQ ID NO：523, SEQ ID NO：524, SEQ ID N
O：525, SEQ ID NO：526, SEQ ID NO：527, SEQ ID N
O：528, SEQ ID NO：529, SEQ ID NO：530, SEQ ID N
O：531, SEQ ID NO：532, SEQ ID NO：533, SEQ ID N
O：534, SEQ ID NO：535, SEQ ID NO：536, SEQ ID N
O：537, SEQ ID NO：538, SEQ ID NO：539, SEQ ID N
O：540, SEQ ID NO：541, SEQ ID NO：542, SEQ ID N
O：543, SEQ ID NO：544, SEQ ID NO：545, SEQ ID N
O：546, SEQ ID NO：547, SEQ ID NO：548, SEQ ID N
O：549, SEQ ID NO：550, SEQ ID NO：551, SEQ ID N
O：552, SEQ ID NO：553, SEQ ID NO：555, SEQ ID N
O：556, SEQ ID NO：557, SEQ ID NO：558, SEQ ID N
O：559, SEQ ID NO：560, SEQ ID NO：561, SEQ ID N
O：562, SEQ ID NO：563, SEQ ID NO：564, SEQ ID N
O：565, SEQ ID NO：566, SEQ ID NO：567, SEQ ID N
O：568, SEQ ID NO：569, SEQ ID NO：570, SEQ ID N
O：571, SEQ ID NO：572, SEQ ID NO：573, SEQ ID N
O：574, SEQ ID NO：575, SEQ ID NO：576, SEQ ID N
O：577, SEQ ID NO：578, SEQ ID NO：579, SEQ ID N
O：580, SEQ ID NO：581, SEQ ID NO：582, SEQ ID N
O：583, SEQ ID NO：584, SEQ ID NO：585, SEQ ID N
O：586, SEQ ID NO：587, SEQ ID NO：588, SEQ ID N
O：589, SEQ ID NO：590, SEQ ID NO：591, SEQ ID N
O：592, SEQ ID NO：593, SEQ ID NO：594, SEQ ID N
O：595, SEQ ID NO：596, SEQ ID NO：597, SEQ ID N
O：598, SEQ ID NO：599, SEQ ID NO：600, SEQ ID N
O：601, SEQ ID NO：602, SEQ ID NO：603, SEQ ID N
O：604, SEQ ID NO：605, SEQ ID NO：606, SEQ ID N
O：607, SEQ ID NO：608, SEQ ID NO：609, SEQ ID N
O：610, SEQ ID NO：611, SEQ ID NO：612, SEQ ID N
O：613, SEQ ID NO：614, SEQ ID NO：615, SEQ ID N
O：616, SEQ ID NO：617, SEQ ID NO：618, SEQ ID N
O：619, SEQ ID NO：620, SEQ ID NO：621, SEQ ID N
O：622, SEQ ID NO：623, SEQ ID NO：624, SEQ ID N
O：625, SEQ ID NO：626, SEQ ID NO：627, SEQ ID N
O：628, SEQ ID NO：629, SEQ ID NO：631, SEQ ID N
O：632, SEQ ID NO：633, SEQ ID NO：634, SEQ ID N
O：635, SEQ ID NO：636, SEQ ID NO：637, SEQ ID N
O：638, SEQ ID NO：639, SEQ ID NO：640, SEQ ID N
O：641, SEQ ID NO：642, SEQ ID NO：643, SEQ ID N
O：644, SEQ ID NO：645, SEQ ID NO：646, SEQ ID N
O：647, SEQ ID NO：648, SEQ ID NO：649, SEQ ID N
O：650, SEQ ID NO：651, SEQ ID NO：652, SEQ ID N
O：653, SEQ ID NO：654, SEQ ID NO：655, SEQ ID N
O：656, SEQ ID NO：657, SEQ ID NO：658, SEQ ID N
O：659, SEQ ID NO：660, SEQ ID NO：661, SEQ ID N
O：662, SEQ ID NO：663, SEQ ID NO：664, SEQ ID N
O：665, SEQ ID NO：666, SEQ ID NO：667, SEQ ID N
O：668, SEQ ID NO：669, SEQ ID NO：670, SEQ ID N
O：671, SEQ ID NO：672, SEQ ID NO：673, SEQ ID N
O：674, SEQ ID NO：675, SEQ ID NO：676, SEQ ID N
O：677, SEQ ID NO：678, SEQ ID NO：679, SEQ ID N
O：680, SEQ ID NO：681, SEQ ID NO：682, SEQ ID N
O：683, SEQ ID NO：684, SEQ ID NO：685, SEQ ID N
O：686, SEQ ID NO：687, SEQ ID NO：688, SEQ ID N
O：690, SEQ ID NO：691, SEQ ID NO：692, SEQ ID N
O：693, SEQ ID NO：694, SEQ ID NO：695, SEQ ID N
O：696, SEQ ID NO：697, SEQ ID NO：698, SEQ ID N
O：699, SEQ ID NO：700, SEQ ID NO：701, SEQ ID N
O：702, SEQ ID NO：703, SEQ ID NO：704, SEQ ID N
O：705, SEQ ID NO：706, SEQ ID NO：707, SEQ ID N
O：708, SEQ ID NO：709, SEQ ID NO：710, SEQ ID N
O：711, SEQ ID NO：712, SEQ ID NO：713, SEQ ID N
O：714, SEQ ID NO：715, SEQ ID NO：716, SEQ ID N
O：717, SEQ ID NO：718, SEQ ID NO：719, SEQ ID N
O：720, SEQ ID NO：721, SEQ ID NO：722, SEQ ID N
O：723, SEQ ID NO：724, SEQ ID NO：725, SEQ ID N
O：726, SEQ ID NO：727, SEQ ID NO：728, SEQ ID N
O：729, SEQ ID NO：730, SEQ ID NO：731, SEQ ID N
O：732, SEQ ID NO：733, SEQ ID NO：734, SEQ ID N
O：735, SEQ ID NO：736, SEQ ID NO：737, SEQ ID N
O：738, SEQ ID NO：739, SEQ ID NO：740, SEQ ID N
O：741, SEQ ID NO：742, SEQ ID NO：743, SEQ ID N
O：744, SEQ ID NO：745, SEQ ID NO：746, SEQ ID N
O：747, SEQ ID NO：748, SEQ ID NO：749, SEQ ID N
O：750, SEQ ID NO：751, SEQ ID NO：752, SEQ ID N
O：753, SEQ ID NO：754, SEQ ID NO：756, SEQ ID N
O：757, SEQ ID NO：758, SEQ ID NO：759, SEQ ID N
O：760, SEQ ID NO：761, SEQ ID NO：762, SEQ ID N
O：763, SＥＱ ＩＤ ＮＯ：764, SEQ ID NO：765, SE
Q ID NO：766, SEQ ID NO：767, SEQ ID NO：768, SEQ
ID NO：769, SEQ ID NO：770, SEQ ID NO：771, SEQ ID
NO：772, SEQ ID NO：773, SEQ ID NO：774, SEQ ID N
O：775, SEQ ID NO：776, SEQ ID NO：777, SEQ ID N
O：778, SEQ ID NO：779, SEQ ID NO：780, SEQ ID N
O：781, SEQ ID NO：782, SEQ ID NO：783, SEQ ID N
O：784, SEQ ID NO：785, SEQ ID NO：786, SEQ ID N
O：787, SEQ ID NO：788, SEQ ID NO：789, SEQ ID N
O：790, SEQ ID NO：791, SEQ ID NO：792, SEQ ID N
O：793, SEQ ID NO：794, SEQ ID NO：795, SEQ ID N
O：796, SEQ ID NO：797, SEQ ID NO：798, SEQ ID N
O：799, SEQ ID NO：800, SEQ ID NO：801, SEQ ID N
O：802, SEQ ID NO：803, SEQ ID NO：804, SEQ ID N
O：805, SEQ ID NO：806, SEQ ID NO：807, SEQ ID N
O：808, SEQ ID NO：809, SEQ ID NO：810, SEQ ID N
O：811, SEQ ID NO：812, SEQ ID NO：813, SEQ ID N
O：814, SEQ ID NO：815, SEQ ID NO：817, SEQ ID N
O：818, SEQ ID NO：819, SEQ ID NO：820, SEQ ID N
O：821, SEQ ID NO：822, SEQ ID NO：823, SEQ ID N
O：824, SEQ ID NO：825, SEQ ID NO：826, SEQ ID N
O：827, SEQ ID NO：828, SEQ ID NO：829, SEQ ID N
O：830, SEQ ID NO：831, SEQ ID NO：832, SEQ ID N
O：833, SEQ ID NO：834, SEQ ID NO：835, SEQ ID N
O：836, SEQ ID NO：837, SEQ ID NO：838, SEQ ID N
O：839, SEQ ID NO：840, SEQ ID NO：841, SEQ ID N
O：842, SEQ ID NO：843, SEQ ID NO：844, SEQ ID N
O：845, SEQ ID NO：846, SEQ ID NO：847, SEQ ID N
O：848, SEQ ID NO：849, SEQ ID NO：850, SEQ ID N
O：851, SEQ ID NO：852, SEQ ID NO：853, SEQ ID N
O：854, SEQ ID NO：855, SEQ ID NO：856, SEQ ID N
O：857, SEQ ID NO：858, SEQ ID NO：859, SEQ ID N
O：860, SEQ ID NO：861, SEQ ID NO：862, SEQ ID N
O：863, SEQ ID NO：864, SEQ ID NO：865, SEQ ID N
O：866, SEQ ID NO：867, SEQ ID NO：868, SEQ ID N
O：869, SEQ ID NO：870, SEQ ID NO：871, SEQ ID N
O：872, SEQ ID NO：873, SEQ ID NO：874, SEQ ID N
O：875, SEQ ID NO：877, SEQ ID NO：878, SEQ ID N
O：879, SEQ ID NO：880, SEQ ID NO：881, SEQ ID N
O：882, SEQ ID NO：883, SEQ ID NO：884, SEQ ID N
O：885, SEQ ID NO：886, SEQ ID NO：887, SEQ ID N
O：888, SEQ ID NO：889, SEQ ID NO：890, SEQ ID N
O：891, SEQ ID NO：892, SEQ ID NO：893, SEQ ID N
O：894, SEQ ID NO：895, SEQ ID NO：896, SEQ ID N
O：897, SEQ ID NO：898, SEQ ID NO：899, SEQ ID N
O：900, SEQ ID NO：901, SEQ ID NO：902, SEQ ID N
O：903, SEQ ID NO：904, SEQ ID NO：905, SEQ ID N
O：906, SEQ ID NO：907, SEQ ID NO：908, SEQ ID N
O：909, SEQ ID NO：910, SEQ ID NO：911, SEQ ID N
O：912, SEQ ID NO：913, SEQ ID NO：914, SEQ ID N
O：915, SEQ ID NO：916, SEQ ID NO：917, SEQ ID N
O：918, SEQ ID NO：919, SEQ ID NO：920, SEQ ID N
O：921, SEQ ID NO：922, SEQ ID NO：923, SEQ ID N
O：924, SEQ ID NO：925, SEQ ID NO：926, SEQ ID N
O：928, SEQ ID NO：929, SEQ ID NO：930, SEQ ID N
O：931, SEQ ID NO：932, SEQ ID NO：933, SEQ ID N
O：934, SEQ ID NO：935, SEQ ID NO：936, SEQ ID N
O：937, SEQ ID NO：938, SEQ ID NO：939, SEQ ID N
O：940, SEQ ID NO：941, SEQ ID NO：942, SEQ ID N
O：943, SEQ ID NO：944, SEQ ID NO：945, SEQ ID N
O：946, SEQ ID NO：947, SEQ ID NO：948, SEQ ID N
O：949, SEQ ID NO：950, SEQ ID NO：951, SEQ ID N
O：952, SEQ ID NO：953, SEQ ID NO：954, SEQ ID N
O：955, SEQ ID NO：956, SEQ ID NO：957, SEQ ID N
O：958, SEQ ID NO：959, SEQ ID NO：960, SEQ ID N
O：961, SEQ ID NO：962, SEQ ID NO：963, SEQ ID N
O：964, SEQ ID NO：965, SEQ ID NO：966, SEQ ID N
O：967, SEQ ID NO：968, SEQ ID NO：969, SEQ ID N
O：970, SEQ ID NO：971, SEQ ID NO：972, SEQ ID N
O：973, SEQ ID NO：974, SEQ ID NO：975, SEQ ID N
O：976, SEQ ID NO：977, SEQ ID NO：979, SEQ ID N
O：980, SEQ ID NO：981, SEQ ID NO：982, SEQ ID N
O：983, SEQ ID NO：984, SEQ ID NO：985, SEQ ID N
O：986, SEQ ID NO：987, SEQ ID NO：988, SEQ ID N
O：989, SEQ ID NO：990, SEQ ID NO：991, SEQ ID N
O：992, SEQ ID NO：993, SEQ ID NO：994, SEQ ID N
O：995, SEQ ID NO：996, SEQ ID NO：997, SEQ ID N
O：998, SEQ ID NO：999, SEQ ID NO：1000, SEQ ID N
O：1001,SEQ ID NO：1002, SEQ ID NO：1003, SEQ ID N
O：1004, SEQ ID NO：1005, SEQID NO：1006, SEQ ID N
O：1007, SEQ ID NO：1008, SEQ ID NO：1009, SEQ IDN
O：1010, SEQ ID NO：1011, SEQ ID NO：1012, SEQ ID
NO：1014, SEQ ID NO：1015, SEQ ID NO：1016, SEQ ID
NO：1017, SEQ ID NO：1018, SEQ ID NO：1019, SEQ I
D NO：1020, SEQ ID NO：1021, SEQ ID NO：1022, SEQ
ID NO：1023, SEQ ID NO：1024, SEQ ID NO：1025, SEQ
ID NO：1026, SEQ ID NO：1027, SEQ IDNO：1028, SEQ
ID NO：1030, SEQ ID NO：1031, SEQ ID NO：1032, SE
Q ID NO：1033, SEQ ID NO：1034, SEQ ID NO：1035, S
EQ ID NO：1036, SEQ ID NO：1037, SEQ ID NO：1038,
SEQ ID NO：1039, SEQ ID NO：1040, SEQ ID NO：1041,
SEQ ID NO：1042, SEQ ID NO：1043, SEQ ID NO：1044,
SEQ ID NO：1045, SEQID NO：1046, SEQ ID NO：1047,
SEQ ID NO：1048, SEQ ID NO：1049, SEQ ID NO：105
0, SEQ ID NO：1051, SEQ ID NO：1052, SEQ ID NO：10
53, SEQ ID NO：1054, SEQ ID NO：1056, SEQ ID NO：1
057, SEQ ID NO：1058, SEQ ID NO：1059,SEQ ID NO：1
061, SEQ ID NO：1062, SEQ ID NO：1063, SEQ ID NO：
1064, SEQID NO：1065, SEQ ID NO：1066, SEQ ID NO：
1067, SEQ ID NO：1068, SEQ IDNO：1069, SEQ ID NO：
1070, SEQ ID NO：1071, SEQ ID NO：1072, SEQ ID N
O：1073, SEQ ID NO：1074, SEQ ID NO：1075, SEQ ID
NO：1076, SEQ ID NO：1077, SEQ ID NO：1078, SEQ ID
NO：1079, SEQ ID NO：1080, SEQ ID NO：1081, SEQ I
D NO：1082, SEQ ID NO：1083, SEQ ID NO：1084, SEQ
ID NO：1085, SEQ IDNO：1086, SEQ ID NO：1087, SEQ
ID NO：1088, SEQ ID NO：1089, SEQ ID NO：1090, SEQ
ID NO：1091, SEQ ID NO：1092, SEQ ID NO：1094, SE
Q ID NO：1095, SEQ ID NO：1096, SEQ ID NO：1097, S
EQ ID NO：1098, SEQ ID NO：1099,SEQ ID NO：1100, S
EQ ID NO：1101, SEQ ID NO：1102, SEQ ID NO：1103,
SEQID NO：1104, SEQ ID NO：1105, SEQ ID NO：1106,
SEQ ID NO：1107, SEQ ID NO：1108, SEQ ID NO：1109,
SEQ ID NO：1110, SEQ ID NO：1111, SEQ ID NO：111
2, SEQ ID NO：1113, SEQ ID NO：1114, SEQ ID NO：11
15, SEQ ID NO：1116,SEQ ID NO：1117, SEQ ID NO：11
18, SEQ ID NO：1119, SEQ ID NO：1120, SEQID NO：11
21, SEQ ID NO：1122, SEQ ID NO：1123, SEQ ID NO：1
124, SEQ IDNO：1125, SEQ ID NO：1126, SEQ ID NO：1
127, SEQ ID NO：1129, SEQ ID NO：1130, SEQ ID NO：
1131, SEQ ID NO：1132, SEQ ID NO：1133, SEQ ID N
O：1134, SEQ ID NO：1135, SEQ ID NO：1136, SEQ ID
NO：1137, SEQ ID NO：1138, SEQ ID NO：1139, SEQ ID
NO：1140, SEQ ID NO：1141, SEQ ID NO：1142, SEQ I
DNO：1143, SEQ ID NO：1144, SEQ ID NO：1145, SEQ I
D NO：1146, SEQ ID NO：1147, SEQ ID NO：1148, SEQ
ID NO：1149, SEQ ID NO：1150, SEQ ID NO：1151, SEQ
ID NO：1152, SEQ ID NO：1153, SEQ ID NO：1154, SE
Q ID NO：1155,SEQ ID NO：1156, SEQ ID NO：1158, SE
Q ID NO：1159, SEQ ID NO：1160, SEQID NO：1161, SE
Q ID NO：1162, SEQ ID NO：1163, SEQ ID NO：1164, S
EQ ID NO：1165, SEQ ID NO：1166, SEQ ID NO：1167,
SEQ ID NO：1168, SEQ ID NO：1169, SEQ ID NO：1170,
SEQ ID NO：1171, SEQ ID NO：1172, SEQ ID NO：117
3,SEQ ID NO：1174, SEQ ID NO：1175, SEQ ID NO：117
6, SEQ ID NO：1177, SEQID NO：1178, SEQ ID NO：117
9, SEQ ID NO：1180, SEQ ID NO：1181, SEQ IDNO：118
2, SEQ ID NO：1183, SEQ ID NO：1184, SEQ ID NO：11
85, SEQ ID NO：1186, SEQ ID NO：1187, SEQ ID NO：1
188, SEQ ID NO：1189, SEQ ID NO：1190, SEQ ID NO：
1192, SEQ ID NO：1193, SEQ ID NO：1194, SEQ ID N
O：1195, SEQ ID NO：1196, SEQ ID NO：1197, SEQ ID
NO：1198, SEQ ID NO：1199, SEQ IDNO：1200, SEQ ID
NO：1201, SEQ ID NO：1202, SEQ ID NO：1203, SEQ ID
NO：1204, SEQ ID NO：1205, SEQ ID NO：1206, SEQ I
D NO：1207, SEQ ID NO：1208, SEQ ID NO：1209, SEQ
ID NO：1210, SEQ ID NO：1211, SEQ ID NO：1213,SEQ
ID NO：1214, SEQ ID NO：1215, SEQ ID NO：1216, SEQ
ID NO：1217, SEQID NO：1218, SEQ ID NO：1219, SEQ
ID NO：1220, SEQ ID NO：1221, SEQ ID NO：1222, SE
Q ID NO：1223, SEQ ID NO：1224, SEQ ID NO：1225, S
EQ ID NO：1226, SEQ ID NO：1227, SEQ ID NO：1228,
SEQ ID NO：1229, SEQ ID NO：1230,SEQ ID NO：1231,
SEQ ID NO：1232, SEQ ID NO：1233, SEQ ID NO：1234,
SEQID NO：1235, SEQ ID NO：1236, SEQ ID NO：1237,
SEQ ID NO：1238, SEQ IDNO：1239, SEQ ID NO：1241,
SEQ ID NO：1242, SEQ ID NO：1243, SEQ ID NO：124
4, SEQ ID NO：1245, SEQ ID NO：1246, SEQ ID NO：12
47, SEQ ID NO：1248, SEQ ID NO：1249, SEQ ID NO：1
250, SEQ ID NO：1251, SEQ ID NO：1252, SEQ ID NO：
1253, SEQ ID NO：1254, SEQ ID NO：1255, SEQ ID N
O：1256, SEQ IDNO：1257, SEQ ID NO：1259, SEQ ID N
O：1260, SEQ ID NO：1261, SEQ ID NO：1262, SEQ ID
NO：1263, SEQ ID NO：1264, SEQ ID NO：1265, SEQ ID
NO：1266, SEQ ID NO：1267, SEQ ID NO：1268, SEQ I
D NO：1269, SEQ ID NO：1270,SEQ ID NO：1271, SEQ I
D NO：1272, SEQ ID NO：1273, SEQ ID NO：1275, SEQI
D NO：1276, SEQ ID NO：1277, SEQ ID NO：1278, SEQ
ID NO：1279, SEQ ID NO：1280, SEQ ID NO：1281, SEQ
ID NO：1282, SEQ ID NO：1283, SEQ ID NO：1284, SE
Q ID NO：1285, SEQ ID NO：1286, SEQ ID NO：1287, S
EQ ID NO：1289,SEQ ID NO：1290, SEQ ID NO：1291, S
EQ ID NO：1292, SEQ ID NO：1293, SEQID NO：1294, S
EQ ID NO：1295, SEQ ID NO：1296, SEQ ID NO：1297,
SEQ IDNO：1298, SEQ ID NO：1299, SEQ ID NO：1300,
SEQ ID NO：1301, SEQ ID NO：1303, SEQ ID NO：1304,
SEQ ID NO：1305, SEQ ID NO：1306, SEQ ID NO：130
7, SEQ ID NO：1308, SEQ ID NO：1310, SEQ ID NO：13
11, SEQ ID NO：1312, SEQ ID NO：1313, SEQ ID NO：1
314, SEQ ID NO：1315, SEQ ID NO：1316, SEQ IDNO：1
317, SEQ ID NO：1318, SEQ ID NO：1319, SEQ ID NO：
1320, SEQ ID NO：1322, SEQ ID NO：1323, SEQ ID N
O：1324, SEQ ID NO：1325, SEQ ID NO：1326, SEQ ID
NO：1327, SEQ ID NO：1328, SEQ ID NO：1330, SEQ ID
NO：1331,SEQ ID NO：1332, SEQ ID NO：1333, SEQ ID
NO：1334, SEQ ID NO：1335, SEQID NO：1336, SEQ ID
NO：1337, SEQ ID NO：1339, SEQ ID NO：1340, SEQ I
D NO：1341, SEQ ID NO：1342, SEQ ID NO：1343, SEQ
ID NO：1344, SEQ ID NO：1345, SEQ ID NO：1346, SEQ
ID NO：1347, SEQ ID NO：1349, SEQ ID NO：1350,SEQ
ID NO：1351, SEQ ID NO：1352, SEQ ID NO：1353, SE
Q ID NO：1354, SEQID NO：1355, SEQ ID NO：1356, SE
Q ID NO：1357, SEQ ID NO：1358, SEQ IDNO：1360, SE
Q ID NO：1361, SEQ ID NO：1362, SEQ ID NO：1363, S
EQ ID NO：1364, SEQ ID NO：1365, SEQ ID NO：1367,
SEQ ID NO：1368, SEQ ID NO：1369, SEQ ID NO：1370,
SEQ ID NO：1371, SEQ ID NO：1375, SEQ ID NO：137
6, SEQ ID NO：1377, SEQ ID NO：1378, SEQ ID NO：13
79, SEQ ID NO：1381, SEQ IDNO：1382, SEQ ID NO：13
83, SEQ ID NO：1384, SEQ ID NO：1385, SEQ ID NO：1
387, SEQ ID NO：1388, SEQ ID NO：1389, SEQ ID NO：
1390, SEQ ID NO：1391, SEQ ID NO：1392, SEQ ID N
O：1393, SEQ ID NO：1395, SEQ ID NO：1396,SEQ ID N
O：1397, SEQ ID NO：1398, SEQ ID NO：1399, SEQ ID
NO：1400, SEQID NO：1402, SEQ ID NO：1403, SEQ ID
NO：1404, SEQ ID NO：1405, SEQ ID NO：1406, SEQ ID
NO：1407, SEQ ID NO：1409, SEQ ID NO：1410, SEQ I
D NO：1412, SEQ ID NO：1413, SEQ ID NO：1414, SEQ
ID NO：1415, SEQ ID NO：1416,SEQ ID NO：1417, SEQ
ID NO：1419, SEQ ID NO：1420, SEQ ID NO：1421, SEQ
ID NO：1422, SEQ ID NO：1423, SEQ ID NO：1424, SEQ
ID NO：1425, SEQ IDNO：1427, SEQ ID NO：1428, SEQ
ID NO：1429, SEQ ID NO：1430, SEQ ID NO：1431, SE
Q ID NO：1432, SEQ ID NO：1433, SEQ ID NO：1434, S
EQ ID NO：1435, SEQ ID NO：1437, SEQ ID NO：1438,
SEQ ID NO：1439, SEQ ID NO：1440, SEQ ID NO：1441,
SEQ ID NO：1442, SEQ ID NO：1444, SEQ ID NO：144
5, SEQ IDNO：1446, SEQ ID NO：1447, SEQ ID NO：144
8, SEQ ID NO：1449, SEQ ID NO：1451, SEQ ID NO：14
52, SEQ ID NO：1453, SEQ ID NO：1454, SEQ ID NO：1
455, SEQ ID NO：1456, SEQ ID NO：1458, SEQ ID NO：
1459, SEQ ID NO：1461,SEQ ID NO：1462, SEQ ID NO：
1463, SEQ ID NO：1464, SEQ ID NO：1465, SEQID NO：
1466, SEQ ID NO：1468, SEQ ID NO：1469, SEQ ID N
O：1470, SEQ ID NO：1472, SEQ ID NO：1474, SEQ ID
NO：1475, SEQ ID NO：1476, SEQ ID NO：1477, SEQ ID
NO：1479, SEQ ID NO：1480, SEQ ID NO：1481, SEQ I
D NO：1482,SEQ ID NO：1483, SEQ ID NO：1484, SEQ I
D NO：1485, SEQ ID NO：1486, SEQID NO：1488, SEQ I
D NO：1490, SEQ ID NO：1491, SEQ ID NO：1492, SEQ
IDNO：1493, SEQ ID NO：1495, SEQ ID NO：1496, SEQ
ID NO：1497, SEQ ID NO：1498, SEQ ID NO：1500, SEQ
ID NO：1502, SEQ ID NO：1503, SEQ ID NO：1504, SE
Q ID NO：1505, SEQ ID NO：1507, SEQ ID NO：1509, S
EQ ID NO：1512, SEQ ID NO：1513, SEQ ID NO：1514,
SEQ ID NO：1515, SEQ ID NO：1517, SEQ IDNO：1518,
SEQ ID NO：1519, SEQ ID NO：1521, SEQ ID NO：1522,
SEQ ID NO：1523, SEQ ID NO：1524, SEQ ID NO：152
5, SEQ ID NO：1527, SEQ ID NO：1528, SEQ ID NO：15
29, SEQ ID NO：1530, SEQ ID NO：1531, SEQ ID NO：1
533,SEQ ID NO：1534, SEQ ID NO：1535, SEQ ID NO：1
536, SEQ ID NO：1538, SEQID NO：1539, SEQ ID NO：1
541, SEQ ID NO：1542, SEQ ID NO：1543, SEQ ID NO：
1544, SEQ ID NO：1546, SEQ ID NO：1548, SEQ ID N
O：1550, SEQ ID NO：1552, SEQ ID NO：1554, SEQ ID
NO：1556, SEQ ID NO：1557, SEQ ID NO：1559,SEQ ID
NO：1560, SEQ ID NO：1561, SEQ ID NO：1562, SEQ ID
NO：1564, SEQID NO：1565, SEQ ID NO：1567, SEQ ID
NO：1568, SEQ ID NO：1570, SEQ IDNO：1572, SEQ ID
NO：1573, SEQ ID NO：1574, SEQ ID NO：1575, SEQ I
D NO：1577, SEQ ID NO：1578, SEQ ID NO：1579, SEQ
ID NO：1581, SEQ ID NO：1582, SEQ ID NO：1583, SEQ
ID NO：1585, SEQ ID NO：1586, SEQ ID NO：1588, SE
Q ID NO：1589, SEQ ID NO：1590, SEQ ID NO：1592, S
EQ ID NO：1593, SEQ IDNO：1595, SEQ ID NO：1597, S
EQ ID NO：1598, SEQ ID NO：1600, SEQ ID NO：1602,
SEQ ID NO：1606, SEQ ID NO：1608, SEQ ID NO：1609,
SEQ ID NO：1610, SEQ ID NO：1611, SEQ ID NO：161
3, SEQ ID NO：1614, SEQ ID NO：1616,SEQ ID NO：161
8, SEQ ID NO：1620, SEQ ID NO：1621, SEQ ID NO：16
23, SEQID NO：1625, SEQ ID NO：1628, SEQ ID NO：16
30, SEQ ID NO：1631, SEQ ID NO：1633, SEQ ID NO：1
634, SEQ ID NO：1638, SEQ ID NO：1641, SEQ ID NO：
1642, SEQ ID NO：1644, SEQ ID NO：1645, SEQ ID N
O：1647, SEQ ID NO：1648,SEQ ID NO：1650, SEQ ID N
O：1651, SEQ ID NO：1653, SEQ ID NO：1654, SEQID N
O：1656, SEQ ID NO：1657, SEQ ID NO：1659, SEQ ID
NO：1661, SEQ IDNO：1663, SEQ ID NO：1665, SEQ ID
NO：1667, SEQ ID NO：1671, SEQ ID NO：1674, SEQ ID
NO：1676, SEQ ID NO：1678, SEQ ID NO：1679, SEQ I
D NO：1681, SEQ ID NO：1684, SEQ ID NO：1686, SEQ
ID NO：1687, SEQ ID NO：1689, SEQ ID NO：1692, SEQ
ID NO：1693, SEQ ID NO：1695, SEQ ID NO：1697, SE
Q IDNO：1698, SEQ ID NO：1702, およびSEQ ID NO：17
03からなる群から選択されるアミノ酸配列もしくはその
断片、または（ｂ）（ａ）のアミノ酸配列において、数
個のアミノ酸が欠失、置換または付加されたアミノ酸配
列からなる、Ｏ１５７：Ｈ７に特異的なポリペプチドに
関する。

【００１４】本発明の腸管出血性病原性大腸菌Ｏ１５
７：Ｈ７に特異的な核酸分子、当該核酸分子に包含され
る遺伝子およびこれにコードされるタンパク質またはポ
リペプチドは、Ｏ１５７：Ｈ７堺株の染色体の全ヌクレ
オチド配列を決定し、非病原性大腸菌Ｋ−１２には存在
しないＯ１５７：Ｈ７特異的領域およびヌクレオチド配
列を同定することにより見出されたものである。本発明
において決定したＯ１５７：Ｈ７の染色体のヌクレオチ
ド配列は、遺伝子データバンクＤＤＢＪにおいて２００
０年６月２６日にアクセッション番号：ＢＡ０００００
７として登録されている。

【００１５】なお、本発明によりＯ１５７：Ｈ７堺株の
染色体の全ヌクレオチド配列が登録された後に、本発明
のものと非常に類似するヌクレオチド配列が２０００年
１０月２２日付けで登録された（ＧｅｎＢａｎｋ／ Ａ
Ｅ００５１７Ｈ）。しかしながら、登録時においてこの
配列データには２つのギャップが存在し、ＡＧＣＴ以外
の文字（未確定塩基）が２６００個以上含まれており、
故に不完全なものである。また、このデータは、２００
１年９月２５日と２００１年１０月２６日付けで更新さ
れているが、一方のギャップの配列のみが決定されてい
るだけであり、２６００以上存在する未確定塩基も残っ
たままである。

【００１６】また、得られた遺伝情報について、ホモロ
ジー検索、予測されるＯＲＦ、その機能等の予測は、ア
ミノ酸配列をＧｅｎＢａｎｋ、ＤＤＢＪ、ＳＷＩＳＳ-
ＰＲＯＴならびにＰＩＲデータベースに見出されるすべ
ての配列との比較当該時術分野において知られたアルゴ
リズム、例えばＢＬＡＳＴアルゴリズム等を用いて実施
することができる。

【００１７】本発明のＯ１５７：Ｈ７に特異的なポリペ
プチドは、以下の表に示す特徴を有するタンパク質また
はポリペプチドであり、そのアミノ酸配列の情報から、
１）機能等が不明なタンパク質、２）機能等は不明であ
るが、他の菌体由来のものと有意なホモロジーを有する
タンパク質、３）挿入配列（Insertion Sequence; IS）
を含むタンパク質、４）ファージ由来のタンパク質、
５）調節因子、６）線毛に関連するタンパク質、７）物
質の輸送に関連するタンパク質、８）リポ多糖合成に関
連するタンパク質、９）代謝に関連するタンパク質、１
０）ＤＮＡ／ＲＮＡのプロセッシングするタンパク質、
１１）病原性に関連するタンパク質、および１２）その
他のタンパク質に分類される。

【００１８】表：腸管出血性病原性大腸菌Ｏ１５７：Ｈ
７に特異的なポリペプチド １）機能が新規なタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 143： 0.610526, 39, 新規 SEQ ID NO: 1438： -0.041667, 109, 新規 SEQ ID NO: 1439： -0.505392, 817, 外膜usherタンパ
ク質前駆体, 外膜usherタンパク質前駆体、例えばYehB
[Escherichia coli K-12] gi|465572|sp|P33341|YEHB#E
COLI (アミノ酸のうち58%一致)に類似 SEQ ID NO: 1440： -0.23304, 228, 推定fimbrial chap
erone, fimbrial, chaperones, 例えばYehC [Escherich
ia coli] gi|465573|sp| P33342|YEHC#ECOLI (221アミ
ノ酸のうち56%一致)に類似, GTGスタート SEQ ID NO: 1441： -0.121469, 178, fimbrial majorタ
ンパク質に類似, YehD[Escherichia coli] gi|465574|s
p|P33343|YEHD#ECOLI (177アミノ酸のうち26%一致), ま
たlong polar fimbrial majorタンパク質 [Salmonella
typhimurium] gi|1170815|sp|P43660|LPFA#SALTY (175
アミノ酸のうち25%一致)に類似 SEQ ID NO: 1442： -0.445877, 474, 新規 SEQ ID NO: 1702： -0.448052, 78, Fプラスミド[Esche
richia coli]のCcdAタンパク質(LetA タンパク質) gi|9
507755|ref|NP#061421.1 (70アミノ酸のうち30%一致)に
類似 SEQ ID NO: 1703： 0.210577, 105, FプラスミドのCcd
Bタンパク質 (LetB タンパク質)[Escherichia coli] gi
|9507756|ref|NP#061422.1 (104アミノ酸のうち35%一
致) に類似 SEQ ID NO: 1663： -0.478836, 190, YABP#ECOLI gi|2
506583|sp|P39220 (168アミノ酸のうち38%一致)に類似 SEQ ID NO: 1387: 0.060434, 370, 推定fimbrial タン
パク質, 推定fimbrial タンパク質 例えば[Escherichia
coli] gi|538781|pir||B47152 (アミノ酸のうち27%一
致), long polar fimbrial minorタンパク質LpfE [Salm
onella typhimurium] gi|1170819|sp|P43664|LPFE#SALT
Y (157アミノ酸のうち27%一致)に類似 SEQ ID NO: 1388： -0.140816 197, 推定 fimbrialタ
ンパク質, 推定 fimbrial タンパク質 YadK [Escherich
ia coli] gi|549488|sp|P37016|YADK#ECOLI (190アミノ
酸のうち40%一致)に類似 SEQ ID NO: 1389： -0.034826, 202, 推定fimbrialタン
パク質, 推定fimbrialタンパク質YadL[Escherichia col
i] gi|549489|sp|P37017|YADL#ECOLI (192アミノ酸のう
ち41%一致)に類似 SEQ ID NO: 1390： -0.011828, 187, 推定fimbrialタン
パク質, 推定fimbrial-様タンパク質 YadM [Escherichi
a coli] gi|549490|sp|P37018|YADM#ECOLI (173アミノ
酸のうち49%一致)に類似 SEQ ID NO: 1391： -0.387529, 867, HTRE#ECOLI gi|17
86332 (849アミノ酸のうち60%一致)に類似 [推定 外膜
porin タンパク質] SEQ ID NO: 1392： -0.250623, 242, ECPD#ECOLI gi|17
86333 (239アミノ酸のうち60%一致) に類似 [推定 pili
n chaperone] SEQ ID NO: 1393： 0.058586, 199, YADN#ECOLI gi|17
86334 (195アミノ酸のうち39%一致)に類似 [推定 fimbr
ial-様タンパク質] SEQ ID NO: 979： -0.333674 99, 新規 SEQ ID NO: 980： -0.245638 150, 新規 SEQ ID NO: 981： -0.622325 216, 新規, TTG スター
ト SEQ ID NO: 982： -0.842466 74, 新規 SEQ ID NO: 983： -0.172956 160, 新規, ハイポセテ
ィカル44.2kDタンパク質YhhZ [Escherichia coli (stra
in K-12)] gi|1176284|sp|P46855|YHHZ#ECOLI (148アミ
ノ酸のうち38%一致); hemolysin-coregulated タンパク
質 Hcp [Vibrio cholerae] gi|7467495|pir||T10891 (1
49アミノ酸のうち32%一致)に類似 SEQ ID NO: 984： -0.448614 470, 新規 SEQ ID NO: 985： -0.402126 1036, 新規, IcmF タン
パク質 [L例えばionellapneumophila] gi|7465644|pir|
|T18341 (1037アミノ酸のうち20%一致)に類似 SEQ ID NO: 986： 0.637097 63, 新規, GTGスター
ト SEQ ID NO: 987： -0.321591 265, 新規, GTGスター
ト SEQ ID NO: 988： -0.206311 207, 新規 SEQ ID NO: 989： 0.001619 248, 新規 SEQ ID NO: 990： -0.129036 924, 推定ATP-依存性Cl
pプロテイナーゼ ATP-結合 chain, ATP-依存性 Clpプロ
テイナーゼ ATP-結合 chains ClpB 例えばgi|7428220|p
ir||T07807 (753アミノ酸のうち40%一致)に類似 SEQ ID NO: 991： -0.11502 254, 新規 [推定 膜タ
ンパク質; IMP]ＳＥＱ ＩＤ ＮＯ： ９９２： -0.34
5146 444, 新規, C-末端部分がハイポセティカルタン
パク質 z29f [Vibrio cholerae] gi|3341578|emb|Caa13
133.1|(104アミノ酸のうち51%一致)に類似 SEQ ID NO: 993： -0.308046, 175, 新規 [ハイポセテ
ィカルリポタンパク質] SEQ ID NO: 994： -0.442019, 427, 新規 SEQ ID NO: 995： -0.298333, 361, 新規 SEQ ID NO: 996： -0.314935, 617, 新規 SEQ ID NO: 997： -0.648175, 138, 新規, base plate
タンパク質 and acidiclysozyme [coliphage T4] gi|13
7980|sp|P09425|VG25#BPT4 (62アミノ酸のうち34%一致)
に類似(低い) SEQ ID NO: 998： -0.380777, 464, 新規, ハイポセテ
ィカル54.5 kDa タンパク質 [Edwardsiella ictaluri]
gi|2708666|gb|aaB92576.1| (461アミノ酸のうち41%一
致)に類似 SEQ ID NO: 999： 0.109459, 75, 新規 SEQ ID NO: 1000： -0.366868, 167, 新規, ハイポセテ
ィカルタンパク質 [Escherichia coli] gi|2920642|gb|
aaC32477.1| (166アミノ酸のうち99%一致); ハイポセテ
ィカル19.5 kDa タンパク質 [Edwardsiella ictaluri]
gi|2708667|gb|aaB92577.1| (148アミノ酸のうち32%一
致)に類似 SEQ ID NO: 1001： -0.39593, 173, 新規 SEQ ID NO: 1002： -0.16, 46, 新規 SEQ ID NO: 1003： -0.416269, 714, 新規, VgrG タン
パク質 例えば[Escherichia coli strain ec11] gi|292
0640|gb|aaC32475.1| (713アミノ酸のうち98%一致)に類
似 1004： -0.707907, 1405, Rhs タンパク質, RhsH タン
パク質 例えば[Escherichia coli strain EC45] gi|292
0634|gb|aaC32471.1| (1264アミノ酸のうち92%一致)に
類似 SEQ ID NO: 1005： -0.704433, 204, 新規, YbeQ [Esch
erichia coli] gi|3025010|sp|P77234| (172アミノ酸の
うち23%一致); YibG [Escherichia coli] gi|418454|sp
|P32106|YIBG#ECOLI (89アミノ酸のうち30%一致)に類似 SEQ ID NO: 1006： -0.305, 61, 新規 SEQ ID NO: 1007： 1.333333, 97, 新規 [ハイポセテ
ィカル膜タンパク質; IMP] SEQ ID NO: 1008： -0.33836, 379, 新規, H repeat-as
sociated タンパク質 例えば[Escherichia coli RhsB e
lement] gi|140772|sp|P28912| (378アミノ酸のうち97%
一致)に類似 SEQ ID NO: 1009： -0.746417, 587, Rhs タンパク質,
Rhs core タンパク質 例えばRhsE [Escherichia coli]
gi|2507113|sp|P24211|RHSE#ECOLIに類似, TTGスタート SEQ ID NO: 1010： 0.701786, 57, 新規, ハイポセティ
カルタンパク質 例えばORF E2 in Rhs element [Escher
ichia coli] gi|2851489|sp|P31991|のN-末端部分 (56
アミノ酸のうち92%一致)に類似 SEQ ID NO: 1011： -0.614943, 88, 新規, ハイポセテ
ィカルタンパク質 例えばORF E2 in Rhs element [Esch
erichia coli] gi|2851489|sp|P31991|のC-末端部分(10
8アミノ酸のうち99%一致)に類似 SEQ ID NO: 1012： -0.31718, 391, 新規, H repeat-as
sociated タンパク質 例えば[Escherichia coli RhsB e
lement] gi|7465875|pir||E64898 (372アミノ酸のうち5
8%一致) に類似, GTGスタート SEQ ID NO: 1094： -0.673765, 325, 推定 インテグラ
ーゼ, インテグラーゼs例えば[Shigella flexneri bact
eriophage V] gi|2465477|gb|aaB72135.1| (305アミノ
酸のうち88%一致)に類似 SEQ ID NO: 1095： -1.175308, 82, 転写 antiterminat
ion タンパク質, 転写 antitermination タンパク質 N
[Bacteriophage lambda] gi|73111|pir||VNBPL (42アミ
ノ酸のうち90%一致) に部分的に類似, may be disrupte
d SEQ ID NO: 1096： -0.473644, 130, 新規, ハイポセテ
ィカルタンパク質 HP1334 [Helicobacter pylori (stra
in 26695)] gi|7464516|pir||F64686のN-末端部分 (111
アミノ酸のうち36%一致)； ハイポセティカルタンパク
質 [Neisseria meningitidis] gi|6900422|emb|CAB7203
2.1|のN-末端部分 (113アミノ酸のうち31%一致)に類似 SEQ ID NO: 1097： -0.28903, 238, prophage リプレッ
サー CI, prophage リプレッサー CI 例えば[Bacteriophage HK9
7] gi|6901592|gb|aaF31095.1|AF069529#8 (AF069529)
(237アミノ酸のうち99%一致)に類似 SEQ ID NO: 1098： -0.486364, 67, Cro リプレッサー,
調節タンパク質 Cro [phage lambda] gi|73101|pir||R
CBPLと同じ; Cro タンパク質 例えば[Bacteriophage HK
97] gi|6901626|gb|aaF31129.1| (66アミノ酸のうち98%
一致)に類似 SEQ ID NO: 1099： -0.309278, 98, 調節 タンパク質 c
II, 調節 タンパク質 cII [Bacteriophage lambda] gi|
73106|pir||QCBP2Lと同じ SEQ ID NO: 1100： -0.622772, 203, ファージ複製タン
パク質, ファージ複製タンパク質 例えばO タンパク質
[Bacteriophage lambda] gi|75891|pir||ORBPLのN-末端
部分(163アミノ酸のうち88%一致)に類似, フレームシフ
トにより中断 SEQ ID NO: 1101： -0.811764, 171, ファージ複製 タ
ンパク質, 複製 タンパク質 例えばタンパク質 O [Bact
eriophage lambda] gi|75891|pir||ORBPLのC-末端部分
(168アミノ酸のうち98%一致)に類似, フレームシフトに
より中断 SEQ ID NO: 1102： -0.002913, 104, 複製タンパク質,
N-末端部分 (1-21アミノ酸)が複製 タンパク質 P 例え
ば[Bacteriophage lambda] gi|75893|pir||PQBPLと同
じ, probably disrupted SEQ ID NO: 1103： -0.026894, 265, 推定 tail fiber
タンパク質, tail fiberタンパク質 例えば[Bacterioph
age HK97] gi|6901608|gb|aaF31111.1| (AF069529) (15
5アミノ酸のうち42%一致)に部分的に類似; Sc/SvQ タン
パク質 (DNA inversion product) [Escherichia coli
プラスミド p15B] 例えばgi|96420|pir||S18690 (159ア
ミノ酸のうち45%一致)に類似 SEQ ID NO: 1104： -0.33198, 198, 新規, ハイポセテ
ィカルタンパク質 例えばYcfA タンパク質 [Escherichi
a coli] gi|2506641|sp|P09153|YCFA#ECOLI (196アミノ
酸のうち65%一致); Gp29 [Bacteriophage HK97] gi|690
1609|gb|aaF31112.1| (192アミノ酸のうち66%一致); T
タンパク質 [Escherichia coli プラスミドp15B] gi|96
096|pir||S18684 (184アミノ酸のうち55%一致) に類似 SEQ ID NO: 1105： -0.586394, 148, 新規, ハイポセテ
ィカルタンパク質 例えばYfdK [Escherichia coli(stra
in K-12)] gi|3915468|sp|P77656|YFDK#ECOLI (144アミ
ノ酸のうち68%一致)に類似 SEQ ID NO: 1106： -0.114706, 137, 推定 tail fiber
タンパク質, ハイポセティカルタンパク質 例えばYfdL
[Escherichia coli (strain K-12)] gi|2495635|sp|P76
508|YFDL#ECOLI (67アミノ酸のうち52%一致); putaive
tail fiberタンパク質 YcfE [Escherichia coli crypti
c prophage e14] gi|7444558|pir||B64861(45ミノ酸の
うち%51一致)に類似 SEQ ID NO: 1107： -0.234783, 185, DNA-invertase, D
NA-invertases 例えばPin [Escherichia coli] gi|7297
8|pir||JWEC (184アミノ酸のうち96%一致)に類似1108
-0.386771, 258, 新規, ハイポセティカルタンパク質 [Deinococcus radioduran
s (strain R1)] gi|7472205|pir||B75431 (249アミノ酸
のうち32%一致)に類似 SEQ ID NO: 1109： 0.763265, 50, 新規 SEQ ID NO: 1110： 0.052227, 248, 推定 転写 調節因
子, 転写調節因子 例えば推定 AraC-type 調節タンパク
質 YdeO gi|6176587|sp|P76135|YDEO#ECOLI (247アミノ
酸のうち34%一致)に類似 SEQ ID NO: 1111： -0.741026, 118, 新規, ハイポセテ
ィカルタンパク質 例えば[Escherichia coli insertion
sequence IS2] gi|140808|sp|P19777|YI22#ECOLIのC-
末端部分(113アミノ酸のうち77%一致)に類似, may be d
isrupted SEQ ID NO: 1112： -0.510941, 394, 推定インテグラー
ゼ, インテグラーゼ 例えば[phage phi-R73] gi|93827|
pir||A42465 (388アミノ酸のうち61%一致)に類似 SEQ ID NO: 1113： -0.468841, 139, 新規, GTGスター
ト SEQ ID NO: 1114： -0.227805, 206, 新規 SEQ ID NO: 1115： -0.045395, 153, 新規 SEQ ID NO: 1116： -0.460952, 211, 新規 SEQ ID NO: 1117： -0.462755, 197, 新規, ハイポセテ
ィカルタンパク質 PFB0765w [malaria parasite] gi|74
94317|pir||E71606 (193アミノ酸のうち24%一致)に類似
(低い), TTGスタート SEQ ID NO: 1118： -0.432979, 189, 新規 SEQ ID NO: 1119： -0.854445, 91, 推定 転写 アクチ
ベーター, Ogr family 例えばLsrS [Rahnellaaquatili
s] gi|93826|pir||E42465 (65アミノ酸のうち41%一致);
deltaタンパク質 [phage phi-R73] gi|93826|pir||E42
465 (76アミノ酸のうち36%一致)に類似 SEQ ID NO: 1120： -0.291803, 184, 推定 polarity su
ppression タンパク質 (amber mutation-suppression);
Psu様タンパク質 例えばPsu [Bacteriophage P4] gi|1
351414|sp|P05460|VPSU#BPP4 (166アミノ酸のうち30%一
致)に類似 SEQ ID NO: 1121： -0.4748, 251, head size determin
ation, head size determination タンパク質 例えばSi
d [phage phi-R73] gi|93821|pir||F42465 (236アミノ
酸のうち22%一致)に類似 SEQ ID NO: 1122： -0.126744, 87, 推定 DNA結合 タン
パク質, ハイポセティカルタンパク質 例えば推定 DNA
結合タンパク質 ORF88 [satellite phage P4] gi|14014
7|sp|P12552|Y9K#BPP4 (82アミノ酸のうち65%一致)に類
似 SEQ ID NO: 1123： 0.40973, 186, CI phage リプレッ
サー, CIリプレッサー 例えば[Bacteriophage P4] gi|1
262833|emb|Caa35902.1| (115アミノ酸のうち67%一致)
に類似 SEQ ID NO: 1124： -0.149315, 74, 新規 SEQ ID NO: 1125： 0.202804, 108, 推定 copy number
controlタンパク質, orf106 [satellite phage P4] gi|
75896|pir||QQBPP4 (98アミノ酸のうち71%一致)に類似 SEQ ID NO: 1126： -0.193179, 778, 推定 DNA primas
e, DNA primases 例えばalpha gene product [satellit
e phage P4] gi|130905|sp|P10277|PRIM#BPP4 (770アミ
ノ酸のうち72%一致)に類似 SEQ ID NO: 1127： -0.333019, 319, 新規, ハイポセテ
ィカルタンパク質ll1401[Synechocystis sp. (strain P
CC 6803)] gi|7470073|pir||S74462 (206アミノ酸のう
ち21%一致)に類似, GTGスタート SEQ ID NO: 1451： 0.23625, 241, 推定 oxidoreductas
e, oxidoreductases 例えば[Streptomyces coelicolor
A3(2)] gi|6137024|emb|CAB59579.1| (237アミノ酸のう
ち55%一致)に類似 SEQ ID NO: 1452： 0.520652, 93, 新規 [ハイポセテ
ィカル膜タンパク質; IMP] SEQ ID NO: 1453： 0.246154, 53, 新規 SEQ ID NO: 1454： -0.246667, 301, 推定 転写調節因
子 (LysR family), 転写調節因子 例えば[Xylella fast
idiosa] gi|9106842|gb|aaF84577.1|AE003999#5(290ア
ミノ酸のうち40%一致) に類似 SEQ ID NO: 1455： -0.309788, 379, 新規, ハイポセテ
ィカルタンパク質 例えば[Pseudomonas aeruginosa] gi
|732227|sp|Q01609|YODE#PSEAE (376アミノ酸のうち54%
一致)に類似 SEQ ID NO: 1456： 0.996977, 398, 推定 輸送タンパク
質, トランスポーター例えばOpdE [Pseudomonas aerugi
nosa] gi|400678|sp|Q01602|OPDE#PSEAE (396アミノ酸
のうち60%一致) に類似 SEQ ID NO: - ： 0.215625, 97, 新規 SEQ ID NO: 1577： -0.388722, 134, 新規, ハイポセテ
ィカルタンパク質 例えばL0013 [Escherichia coli O15
7:H7 strain EDL933]] gi|3414881|gb|aaC31492.1| (13
3アミノ酸のうち99%一致)に類似, GTGスタート SEQ ID NO: 1578： 0.010435, 116, 新規, ハイポセテ
ィカルタンパク質 例えばL0014 [Escherichia coli O15
7:H7 strain EDL933]] gi|3288157|emb|Caa11510.1| (1
15アミノ酸のうち100%一致)に類似 SEQ ID NO: 1579： -0.445312, 513, 新規, ハイポセテ
ィカルタンパク質 例えばL0015 [Escherichia coli O15
7:H7 strain EDL933]] gi|3414883|gb|aaC31494.1| (51
2アミノ酸のうち100%一致)に類似 SEQ ID NO: - ： -0.171316, 381, 推定 NADH-依存性 f
lavin oxidoreductase,YqiG [Bacillus subtilis] gi|1
731054|sp|P54524|YQIG#BACSU (380アミノ酸のうち40%
一致)に類似 SEQ ID NO: 1495： -0.089543, 307, 新規, ハイポセテ
ィカルタンパク質 例えば[Escherichia coli K-12] gi|
3183244|sp|P76049|YCJY#ECOLI (294アミノ酸のうち40%
一致)に類似 [in Tpx-Fnr intergenic 領域] SEQ ID NO: 1496： -0.058117, 309, 推定 転写調節因
子, 転写調節因子 例えば[Escherichia coli] gi|24953
98|sp|P75836|YCAN#ECOLI (291アミノ酸のうち38%一致)
に類似 [in DmsC-PflA intergenic 領域] SEQ ID NO: 1497： -0.218644, 119, 新規 SEQ ID NO: 1498： -0.25445, 192, 推定 oxidoreducta
se, [aldo/keto reductase family] oxidoreductaseのN
-末端部分 (5-192／286アミノ酸)に類似, [Thermotoga
maritima] gi|7431104|pir||A72308 (185アミノ酸のう
ち59%一致)に類似 SEQ ID NO: - ： -0.289344, 1418, 推定 invasin, 推
定 膜タンパク質 b1978 [Escherichia coli] gi|746677
9|pir||D64962 (1352アミノ酸のうち32%一致)に類似vas
ins 例えば[Yersinia pestis] gi|726319|gb|aaA96352.
1| (661アミノ酸のうち36%一致)に類似, intimins 例え
ば[Escherichia coli strain 4221] gi|1947048|gb|aaS
EQ ID NO: 酸B52913.1| (874アミノ酸のうち30%一致)に
類似 SEQ ID NO: - ： -0.170242, 290, 推定reductase, red
uctases 例えばoxidoreductase [Thermotoga maritima]
gi|7431104|pir||A72308 (281アミノ酸のうち46%一致)
に類似 SEQ ID NO: 1479： 0.107317, 83, 新規, ハイポセティ
カルタンパク質YaiU [Escherichia coli] gi|2495526|s
p|P75700|YAIU#ECOLI (54アミノ酸のうち37%一致)に類
似 [推定 flagellin structuralタンパク質 in HemB-sb
mA intergenic 領域] SEQ ID NO: 1480 -0.156319, 365, 推定 adhesin, hig
h molecular weight adhesin 例えばHmwA [Haemophilus
influenzae] gi|5929966|gb|aaD56660.1|AF180944#1
(199アミノ酸のうち19%一致)に類似 SEQ ID NO: 1481： -0.088933, 254, 新規 1482： -0.235772, 124, 新規, ハイポセティカルタン
パク質 [Escherichia coli] gi|2506596|sp|P21514|YAH
A#ECOLIの部分 (38アミノ酸のうち48%一致)に類似;調節
因子 例えばBvgA [Bordetella bronchiseptic] gi|1151
57|sp|P16574|BVGA#BORPE (49アミノ酸のうち44%一致)
に類似, GTGスタート SEQ ID NO: 1483： 0.530909, 56, 新規 1484： -0.632692, 53, 推定 fimbriae調節タンパク質,
invertase (partial),type 1 fimbriae 調節 タンパク
質 例えばFimE [Escherichia coli K-12] gi|120167|sp
|P04741|FIME#ECOLIのC-末端部分 (49アミノ酸のうち73
%一致); FimB [Escherichia coli] gi|729489|sp|P0474
2|FIMB#ECOLI (75アミノ酸のうち63%一致) に類似 SEQ ID NO: 1485： -0.365069, 147, 推定 fimbriae 調
節タンパク質, invertase, type 1 fimbriae 調節 タン
パク質 例えばFimB [Escherichia coli K-12] gi|72948
9|sp|P04742|FIMB#ECOLI の部分(114アミノ酸のうち49%
一致);FimE [Escherichia coli] gi|120167|sp|P04741|
FIME#ECOLI (113アミノ酸のうち42%一致) に類似, TTG
スタート, probably interrupted SEQ ID NO: 1486： 1.684091, 45, 新規 SEQ ID NO: - ： 0.114286, 50, 新規 SEQ ID NO: 1500： -0.450414, 1328, 推定 adhesin, A
idA-I adhesin前駆体 例えば[Escherichia coli プラス
ミド F] gi|8918851|dbj|Baa97898.1| (1179アミノ酸の
うち45%一致)に類似; IgA1 プロテアーゼ homolog MisL
[Salmonella typhimurium pathogenicity island SPI-
3] gi|4324610|gb|aaD16954.1| (768アミノ酸のうち39%
一致)に類似; VirG [Shigella flexneri] gi|96922|pir
||A32247(1014アミノ酸のうち31%一致)に類似 SEQ ID NO: 1502： -0.081707, 329, 推定 sugar-結合
タンパク質, sugar-結合タンパク質 例えばb1516 [Esch
erichia coli] gi|7466925|pir||G64905 (309アミノ酸
のうち27%一致)に類似 SEQ ID NO: 1503： -0.030233, 87, 推定 ABCトランス
ポーター ATP-結合タンパク質, ABC トランスポーターA
TP-結合タンパク質 例えば[Streptomyces coelicolor A
3(2)] gi|7479110|pir||T34924 のN-末端部分(82アミノ
酸のうち48%一致)に類似 [also to AraG - E.coli] SEQ ID NO: 1504： 0.144865, 371, 推定 ABCトランス
ポーターATP-結合タンパク質, sugar ABCトランスポー
ターATP-結合 タンパク質 例えば[Bacillus subtilis]
gi|7404442|sp|P36947|RBSA#BACSU のC-末端部分(380ア
ミノ酸のうち36%一致)に類似 SEQ ID NO: 1505： 0.929412, 324, 推定 ABCトランス
ポーター (permease), ABC 輸送系 permeases 例えばRb
sC[Bacillus subtilis] gi|7446897|pir||B69690(299ア
ミノ酸のうち34%一致), [Escherichia coli] gi|400960
|sp|P04984|RBSC#ECOLI (298アミノ酸のうち31%一致)に
類似 SEQ ID NO: - ： 1.081132, 319, 推定 ABC輸送系 perm
ease, ABC輸送系 permeases 例えばRbsC [Escherichia
coli] gi|78833|pir||C26304 (291アミノ酸のうち35%一
致), [Bacillus subtilis] gi|7446897|pir||B69690 (2
90アミノ酸のうち34%一致)に類似 SEQ ID NO: ： -0.118928, 318, 推定 転写調節因子, a
raC-family 転写調節因子 例えばAdpA [Streptomyces c
oelicolor A3(2)] gi|7544056|emb|CAB87229.1(311アミ
ノ酸のうち39%一致)に類似 SEQ ID NO: 1606： -0.14084, 263, YDDR#BACSU gi|747
4951|pir||H69776 (259アミノ酸のうち47%一致)に類似 1360： -0.236079, 353, probably ABCトランスポータ
ーATP-結合タンパク質 (probably ferric 輸送系), ABC
トランスポーターATP-結合タンパク質 例えばAfuC [Es
cherichia coli K-12] gi|2506109|sp|P37009|AFUC#ECO
LI (352アミノ酸のうち94%一致)に類似 SEQ ID NO: 1361： 0.860259, 693, 推定 ferric輸送系
permease, ferric輸送系permeases 例えばAfuB [Actino
bacillus pleuropneumoniae] gi|7387527|sp|Q44123|AF
UB#ACTPL (671アミノ酸のうち66%一致)に類似 SEQ ID NO: 1362： -0.371429, 344, 推定 periplasmic
-iron-結合タンパク質,periplasmic-iron-結合タンパク
質 例えばAfuA [Actinobacillus pleuropneumoniae] gi
|1469286|gb|aaB05032.1| (343アミノ酸のうち72%一致)
に類似 SEQ ID NO: 1363： 0.585714, 435, 推定 調節因子, he
xosephosphate 輸送系調節タンパク質 例えばUhpC [Esc
herichia coli K-12] gi|136770|sp|P09836|UHPC#ECOLI
(415アミノ酸のうち53%一致)に類似 SEQ ID NO: 1364： 0.329436, 514, 推定 センサー his
tidine タンパク質 キナーゼ, センサータンパク質 キ
ナーゼ 例えばhexosephosphate輸送系センサータンパク
質 UhpB [Escherichia coli K-12] gi|7429062|pir||RG
ECUB (497アミノ酸のうち35%一致)に類似 SEQ ID NO: 1365： 0.151196, 210, 推定 転写調節因子
(probably response 調節因子), 転写調節因子 例えば
hexose phosphate 輸送系 調節 タンパク質 UhpA[Salmo
nella typhimurium] gi|136767|sp|P27667|UHPA#SALTY
(202アミノ酸のうち49%一致); UhpA [Escherichia col
i] gi|136766|sp|P10940|UHPA#ECOLI (202アミノ酸のう
ち48%一致)に類似 SEQ ID NO: - ： 0.595302, 150, 新規 SEQ ID NO: 1625： -0.624948, 482, 新規 SEQ ID NO: 1697： -0.57125, 81, 新規, ハイポセティ
カルタンパク質 [Yersinia enterocolitica] gi|351103
2|gb|aaC33681.1の部分(80アミノ酸のうち1-70位) (70
アミノ酸のうち45%一致)に類似 SEQ ID NO: 1698： -0.341936, 94, 新規, ハイポセテ
ィカルタンパク質 (99アミノ酸) [Yersinia pestis] gi
|3822096|gb|aaC69816.1 (89アミノ酸のうち35%一致)に
類似 SEQ ID NO: 1602： -0.638432, 524, 新規 SEQ ID NO: 1056： -0.363636, 452, 推定 トランスポ
ーター (外膜タンパク質), 外膜輸送タンパク質 例えば
CyaE タンパク質 [Bordetella pertussis] gi|117799|s
p|P11092|CYAE#BORPE (385アミノ酸のうち25%一致)に類
似 SEQ ID NO: 1057： 0.097741, 1462, 新規, ハイポセテ
ィカルタンパク質 例えば[Synechocystis sp. strain P
CC 6803] gi|7469433|pir||S76109 (1384アミノ酸のう
ち33%一致) に類似; RTX タンパク質 [Aeromonas salm
onicida] gi|6752871|gb|aaF27914.1|AF218037#1 (1384
アミノ酸のうち33%一致)に類似 SEQ ID NO: 1058： -, 5292, 新規, ハイポセティカル
タンパク質 例えば[Synechocystis sp. strain PCC 680
3] gi|7469433|pir||S76109 (2014アミノ酸のうち36%一
致)に類似; RTX タンパク質 [Aeromonas salmonicida]
gi|6752871|gb|aaF27914.1|AF218037#1 (2051アミノ酸
のうち36%一致); hemagglutinin [Streptococcus gordo
nii] gi|8885520|dbj|Baa97453.1| (2056アミノ酸のう
ち35%一致)に類似, GTGスタート SEQ ID NO: 1059： 0.082011, 707, 推定 トランスポー
ター, トランスポーター(ATP-結合 タンパク質) 例えば
LktB [Actinobacillus actinomycetemcomitans]gi|1263
57|sp|P23702|HLYB#ACTAC (690アミノ酸のうち26%一致)
に類似 SEQ ID NO: - ： -0.275448, 392, 推定 トランスポー
ター, 膜融合タンパク質例えば[Sinorhizobium melilot
i] gi|4689001|emb|CAB41456.1| (372アミノ酸のうち28
%一致)に類似 SEQ ID NO: 1559： -0.082857, 141, 新規 SEQ ID NO: 1560： 0.236364, 56, 新規 SEQ ID NO: 1561： -0.525147, 339, 推定 adhesin/inv
asin, surface タンパク質 [Xylella fastidiosa] gi|9
106565|gb|aaF84338.1|AE003982#11 (313アミノ酸のう
ち22%一致); 推定 adhesin/invasin [Neisseria mening
itidis MC58] gi|7227256|gb|aaF42321.1| (337アミノ
酸のうち23%一致) に類似 SEQ ID NO: 1562： -0.5825, 121, 新規 SEQ ID NO: - ： -0.746575, 74, 新規, ハイポセティ
カルタンパク質 YahH [Escherichia coli] gi|2495514|
sp|P75690|YAHH#ECOLIの部分(23アミノ酸のうち69%一
致) に類似 SEQ ID NO: 1303： -0.35, 379, H repeat-associated
タンパク質, H repeat-associated タンパク質 in RhsB
element [Escherichia coli] gi|140772|sp|P28912|YH
HI#ECOLI (378アミノ酸のうち97%一致)に類似 SEQ ID NO: 1304： -0.745946, 445, Rhsタンパク質,
推定 Rhs タンパク質treptomyces coelicolor A3(2) gi
|7321289|emb|CAB82067.1| (285アミノ酸のうち34%一
致); RhsE タンパク質 - E. coli gi|2507113|sp|P2421
1| (139アミノ酸のうち36%一致)に類似, GTGスタート SEQ ID NO: 1305： -0.224444, 136, 新規 SEQ ID NO: 1306： -0.577477, 1617, Rhsタンパク質,
推定 Rhsタンパク質 [Streptomyces coelicolor A3(2)]
gi|7321289|emb|CAB82067.1| (857アミノ酸のうち30%
一致); RhsH タンパク質 [Escherichia coli strain ec
45] gi|2920634|gb|aaC32471.1| (919アミノ酸のうち25
%一致) に類似 SEQ ID NO: 1307： -0.498693, 154, 新規 SEQ ID NO: 1308： -0.509795, 634, 推定 Vgrタンパク
質, Vgrタンパク質 例えば[Escherichia coli strain e
c11] gi|2920640|gb|aaC32475.1| (529アミノ酸のうち9
3%一致)に類似 SEQ ID NO: 1474： -0.281303, 354, YBGO#ECOLI gi|17
86935 (353アミノ酸のうち87%一致) に類似, しかしN-
末端は異なる SEQ ID NO: 1475： -0.419342, 244, YBGP#ECOLI gi|17
86936 (242アミノ酸のうち78%一致) に類似[推定 chape
rone] SEQ ID NO: 1476： -0.430567, 724, (1-723/818アミノ
酸) of YBGQ#ECOLI gi|1786937のN-末端部分(723アミノ
酸のうち84%一致)に類似 [推定 外膜タンパク質]SEQ ID
NO: 1477： -0.026943, 194, YBGD#ECOLI gi|1786938
(188アミノ酸のうち79%一致) [推定 fimbrial-様タン
パク質] に類似 SEQ ID NO: 1275： -0.0701, 302, 推定 転写調節因子,
転写調節因子 例えばglycine cleavage system 転写ア
クチベーター (gcv operon アクチベーター) - Escheri
chia coli gi|417043|sp|P32064|GCVA#ECOLI (300アミ
ノ酸のうち31%一致)に類似 SEQ ID NO: 1276： -0.4, 201, 推定 cob(I)alamin ade
nosyltransferase, cob(I)alamin adenosyltransferase
s (corrinoid adenosyltransferases) 例えば[Escheric
hia coli] gi|115148|sp|P13040|BTUR#ECOLI (200アミ
ノ酸のうち67%一致) に類似 SEQ ID NO: 1277： -0.259636, 551, 推定 fumarate hy
dratase,fumarate hydratases 例えばfumarate hydrata
se class I, aerobic (fumarase) - Escherichia coli
gi|120598|sp|P00923|FUMA#ECOLI (545アミノ酸のうち6
8%一致)に類似 SEQ ID NO: 1278： 0.92183, 427, 推定 輸送タンパク
質, glutamate/aspartate輸送タンパク質 (proton glut
amate symport タンパク質) 例えば[Bacillus stearoth
ermophilus] gi|121467|sp|P24943|GLTT#BACST (416ア
ミノ酸のうち38%一致)に類似, またC4-dicarboxylate輸
送タンパク質 例えば[Rhizobium l 例えばuminosarum]
gi|231980|sp|Q01857|DCTA#RHILE (400アミノ酸のうち3
7%一致)に類似 SEQ ID NO: 1279： -0.126667, 106, 新規 SEQ ID NO: 1280： -0.052632, 457, 新規, unnamedタ
ンパク質 product [Citrobacter amalonaticus] gi|318
4398|dbj|Baa28710.1| (284アミノ酸のうち93%一致) に
類似 SEQ ID NO: 1281： -0.051816, 414, 3-methylaspartat
e ammonialyase (beta-methylaspartase), 3-methylasp
artate ammonia-lyases (beta-methylaspartases) 例え
ば[Citrobacter amalonaticus] gi|3184397|dbj|Baa287
09.1| (413アミノ酸のうち93%一致); [Clostridium tet
anomorphum] gi|729971|sp|Q05514|MaaL#CLOTT (409ア
ミノ酸のうち55%一致)に類似 SEQ ID NO: 1282： -0.214345, 482, probable glutama
te mutase E (methylaspartate mutase E), glutamate
mutases 例えば[Citrobacter amalonaticus] gi|318439
6|dbj|Baa28708.1| (481アミノ酸のうち90%一致), [Clo
stridium tetanomorphum] gi|729586|sp|Q05509|GLME#C
LOTT (481アミノ酸のうち57%一致) に類似 SEQ ID NO: 1283： -0.058875, 463, probable glutama
te mutase L (methylaspartate mutase L), glutamate
mutase L (methylaspartate mutase L) 例えば[Clostri
dium tetanomorphum] gi|444421|prf||1907157C (449ア
ミノ酸のうち32%一致) に類似 SEQ ID NO: 1284： 0.061074, 150, probable glutamat
e mutase S (methylaspartate mutase S), glutamate m
utase S (methylaspartate mutase S) 例えば[Clostrid
ium Cochlearium] gi|7245512|pdb|1CCW|A (156アミノ
酸のうち57%一致)に類似 SEQ ID NO: 1285： -0.278182, 56, 新規 SEQ ID NO: 1286： -0.114286, 141, 新規 SEQ ID NO: 1287： -0.327388, 315, 新規 SEQ ID NO: 928： -0.906945, 73, excisionase, excis
ionase [BacteriophageHK022] gi|1722835|sp|P11683|V
XIS#BP434と同じ; excisionase [Bacteriophagelambda]
gi|139680|sp|P03699|VXIS#LAMBD (72アミノ酸のうち9
8%一致)に類似 SEQ ID NO: 929： -0.565455, 56, 新規, ハイポセティ
カルタンパク質 ORF55 [Bacteriophage 434] gi|801889
|gb|aaA67903.1| (55アミノ酸のうち98%一致) に類似 SEQ ID NO: 930： -0.0725, 41, 新規, ハイポセティカ
ルタンパク質 ORF-91 [phage 434] gi|93720|pir||A273
54 (28アミノ酸のうち82%一致)に類似 SEQ ID NO: 931： 0.247159, 177, 新規 [推定 膜タン
パク質; IMP] SEQ ID NO: 932： -0.605479, 74, 新規, C4-type zinc
finger タンパク質 (TraR family) 例えばgi|7649830|
dbj|Baa94108.1| (73アミノ酸のうち98%一致) に類似, SEQ ID NO: 933： -0.346237, 94, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage 933W] gi|58816
02|dbj|Baa84293.1| (93アミノ酸のうち97%一致); orf6
1 [Bacteriophage lambda] (46アミノ酸のうち95%一致)
に類似 SEQ ID NO: 934： -0.079365, 64, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage VT2-Sa] gi|588
1603|dbj|Baa84294.1| (61アミノ酸のうち96%一致), or
f63 [Bacteriophage lambda] gi|508994|gb|aaA96567.1
| (63アミノ酸のうち92%一致) に類似 SEQ ID NO: 935： -0.246667, 61, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage 933W] gi|45853
89|gb|aaD25417.1|AF125520#12 (60アミノ酸のうち95%
一致), orf60a [Bacteriophage lambda] gi|508995|gb|
aaA96568.1| (60アミノ酸のうち93%一致)に類似 SEQ ID NO: 936： -0.359735, 227, exonuclease, exon
ucleases 例えば[Bacteriophage lambda] gi|119702|sp
|P03697|EXO#LAMBD (226アミノ酸のうち98%一致)に類似 SEQ ID NO: 937： -1.293333, 61, 新規, NinEタンパク
質 例えば[Bacteriophage 21] gi|4539480|emb|CAB3998
9.1| (60アミノ酸のうち95%一致) に類似 SEQ ID NO: 938： -0.675, 57, 新規, NinFタンパク質
例えば[Bacteriophage 21] gi|4539481|emb|CAB39990.1
| (56アミノ酸のうち92%一致) に類似, GTGスタート SEQ ID NO: 939： -1.100483, 208, 新規, NinGタンパ
ク質 例えば[Bacteriophage 21] gi|4539482|emb|CAB39
991.1| (204アミノ酸のうち95%一致)に類似 SEQ ID NO: 940： -0.243891, 222, serine/threonin
タンパク質phosphatase,serine/threonin タンパク質ph
osphatase 例えば[Bacteriophage lambda] gi|130792|s
p|P03772|PP#LAMBD (221アミノ酸のうち95%一致)に類似 SEQ ID NO: 941： -0.257367, 320, 新規, [推定 外膜
タンパク質; OMP]推定 外膜タンパク質 [Helicobacter
pylori (strain J99)] gi|7465285|pir||H71907 (297ア
ミノ酸のうち19%一致) に類似(低い) SEQ ID NO: 942： -0.396506, 230, antitermination, antiterminators 例えばタンパク質 Q [Bacteriophage
82] gi|132277|sp|P13870|RegQ#BP82に類似 SEQ ID NO: 943： 0.576577, 223, 新規, [ハイポセテ
ィカル膜タンパク質; IMP] orf14 [Actinobacillus act
inomycetemcomitans] gi|7592819|dbj|Baa94406.1| (22
8アミノ酸のうち29%一致); TfpB タンパク質 [Moraxell
a bovis] gi|141258|sp|P20666|TFPB#MORBO (190アミノ
酸のうち26%一致)に類似 SEQ ID NO: 944： -0.288636, 133, 新規 SEQ ID NO: 945： 0.109859, 72, holinタンパク質, ho
linタンパク質 例えば[Bacteriophage 933W] gi|449980
8|emb|CAB39307.1| (71アミノ酸のうち92%一致)に類似 SEQ ID NO: 946： -0.186061, 166, endolysin (lysozy
me), endolysins (lysozyme) 例えばRタンパク質[Bacte
riophage 21] gi|67436|pir||LZBP21 (165アミノ酸のう
ち93%一致)に類似 SEQ ID NO: 947： -0.409678, 156, 新規, GTGスター
ト SEQ ID NO: 948： -0.060294, 69, リボソームタンパク
質 L31-様 タンパク質,ハイポセティカルタンパク質 例
えばリボソームタンパク質 L31 homolog ykgM in intF-
eaeH intergenic領域[Escherichia coli K-12] gi|3025
204|sp|P71302|YKGM#ECOLI (86アミノ酸のうち93%一致)
に類似, GTGスタート SEQ ID NO: 949： 0.736, 51, 新規, GTGスタート SEQ ID NO: 950： 0.613043, 93, 推定 colicin immuni
tyタンパク質, colicinimmunity タンパク質 例えばcol
icin E1 immunityタンパク質 gi|124395|sp|P02985|IMM
1#ECOLI (107アミノ酸のうち25%一致)に類似 SEQ ID NO: 951： -0.444172, 164, 新規, [推定 膜タ
ンパク質; IMP] ハイポセティカルタンパク質 MAL4P2.2
6 [Plasmodium falciparum] gi|6562728|emb|CAB62867.
1| (106アミノ酸のうち29%一致)に類似(低い) SEQ ID NO: 952： -0.572571, 701, 新規 SEQ ID NO: 953： -0.84, 71, 新規 SEQ ID NO: 954： -0.437433, 375, 新規, ハイポセテ
ィカルタンパク質 例えば[Pseudomonas putida] gi|299
5633|gb|aaC98738.1|のC-末端部分 (200アミノ酸のうち
40%一致); L0015 [Escherichia coli] gi|3414883|gb|a
aC31494.1| (200アミノ酸のうち39%一致)に類似, GTGス
タート SEQ ID NO: 955： -1.301176, 86, 新規, ハイポセティ
カルタンパク質 例えばorf29 [Escherichia coli] gi|6
009405|dbj|Baa84864.1| (136アミノ酸のうち37%一致);
L0013 [Escherichia coli] gi|3414881|gb|aaC31492.1
| (124アミノ酸のうち38%一致) に類似 SEQ ID NO: 956： -0.21966, 708, 新規, ハイポセティ
カルタンパク質 例えばorf50 [Escherichia coli] gi|6
009426|dbj|Baa84885.1| (106アミノ酸のうち71%一致);
L0014 [Escherichia coli] gi|3288157|emb|Caa11510.
1| (116アミノ酸のうち64%一致)に類似 SEQ ID NO: 957： 0.07541, 123, 新規, ハイポセティ
カルタンパク質 例えばL0015 [Escherichia coli] gi|3
414883|gb|aaC31494.1| (503アミノ酸のうち61%一致)に
類似 SEQ ID NO: 958： -0.213187, 92, 新規,ハイポセティ
カルタンパク質 例えば57.8 kD タンパク質 [Pseudomon
as putida]gi|2496740|sp|P55630|Y4QI#RHISN (232アミ
ノ酸のうち37%一致)に類似 SEQ ID NO: 959： -0.348958, 193, 新規,ハイポセティ
カルタンパク質 例えば20.3K タンパク質 [Agrobacteri
um tumefaciens IS1131] gi|95090|pir||JC1151 (101ア
ミノ酸のうち41%一致) に類似 SEQ ID NO: 960： -0.065414, 134, 新規 SEQ ID NO: 961： -0.125911, 248, immunity to R478
phage/colicin/tellurite resistance cluster, TerW
[プラスミド R478] gi|1354147|gb|aaC44736.1| (155ア
ミノ酸のうち99%一致)に類似 SEQ ID NO: 962： -0.134375, 129, 新規 SEQ ID NO: 963： -0.372477, 110, 新規, ハイポセテ
ィカルタンパク質 例えば[Deinococcus radiodurans] g
i|7472167|pir||B75302 (305アミノ酸のうち42%一致)に
類似 SEQ ID NO: 964： -0.581686, 1022, 新規, ハイポセテ
ィカルタンパク質 例えば[Streptomyces coelicolor A3
(2)] gi|7472048|pir||A75302 (260アミノ酸のうち34%
一致)に類似 SEQ ID NO: 965： -0.305505, 110, 新規, ハイポセテ
ィカルタンパク質 例えば[Streptomyces coelicolor A3
(2)] gi|8246803|emb|CAB92838.1| (97アミノ酸のうち4
5%一致)に類似 SEQ ID NO: 966： -0.476724, 233, 新規, ハイポセテ
ィカルタンパク質 例えば[Serratia marcescens] gi|16
95868|gb|aaB37122.1| (167アミノ酸のうち100%一致)に
類似 SEQ ID NO: 967： -0.431156, 200, 新規, ハイポセテ
ィカルタンパク質 例えば[Serratia marcescens] gi|16
95869|gb|aaB37123.1| (197アミノ酸のうち99%一致);
[Deinococcus radiodurans (strain R1)] gi|7471591|p
ir||F75301 (364アミノ酸のうち38%一致)に類似 SEQ ID NO: 968： 0.120465, 216, 新規, ハイポセティ
カルタンパク質 例えば[Serratia marcescens] gi|1695
870|gb|aaB37124.1| (173アミノ酸のうち99%一致); [Se
rratia marcescens] gi|1695871|gb|aaB37125.1| (53ア
ミノ酸のうち98%一致); [Deinococcus radiodurans] gi
|7471522|pir||E75301 (286アミノ酸のうち28%類似)に
類似 SEQ ID NO: 969： -0.357696, 1138, possible telluri
um resistance, TerZ タンパク質 例えば [Serratia ma
rcescens] gi|6094454|sp|Q52353| (193アミノ酸のうち
98%一致)に類似 SEQ ID NO: 970： -0.31005, 200, tellurium resistan
ce, TerA タンパク質 例えば [Serratia marcescens] g
i|5702379|gb|aaD47285.1|AF168355#3 (385アミノ酸の
うち67%一致) に類似 SEQ ID NO: 971： -0.739041, 439, tellurite resista
nce, TerB タンパク質例えば [Serratia marcescens] g
i|950680|gb|aaA86848.1| (151アミノ酸のうち100%一
致)に類似 SEQ ID NO: 972： -0.284314, 103, tellurium resista
nce, TerC タンパク質例えば [Serratia marcescens] g
i|6226214|sp|Q52356|TERC#SERMA (346アミノ酸のうち1
00%一致)に類似 SEQ ID NO: 973： -0.460736, 327, tellurium resista
nce, terD タンパク質例えば[Serratia marcescens] gi
|6094448|sp|Q52357|TERD#SERMA (192アミノ酸のうち10
0%一致)に類似 SEQ ID NO: 974： -0.541515, 331, possible telluriu
m resistance, gi|7108482|gb|aaF36434.1|AF126104#3
TLRB#ECOLI (191アミノ酸のうち100%一致)と同じ; TerE
タンパク質 例えば[Serratia marcescens] gi|6094449
|sp|Q52358|TERE#SERMA (191アミノ酸のうち98%一致)
に類似 SEQ ID NO: 975： -0.394881, 294, 新規 SEQ ID NO: 976： 0.154545, 45, tellurium resistanc
e, gi|7108481|gb|aaF36433.1|AF126104#2 TRLA#ECOLI
(102アミノ酸のうち100%一致)と同じ; TerF タンパク質
例えば.[Serratia marcescens] gi|7387491|gb|aaA868
52.2| TERF#SERMA(102アミノ酸にのうち94%一致)に類似 SEQ ID NO: 977： -0.360345, 233, 新規, GTGスター
ト SEQ ID NO: 1550： -0.338059, 671, adhesin, Ihaadhe
sin [Escherichia coliO157:H7 strain 86-24] gi|7108
480|gb|aaF36432.1|AF126104#1 IHA#ECOLI (696アミノ
酸のうち99%一致); exogenous ferric siderophore レ
セプター R4 [Escherichia coli strain CFT073] gi|36
61500|gb|aaC61730.1| gi|3661500|gb|aaC61730.1| (66
9アミノ酸のうち99%一致)に類似 SEQ ID NO: 1665： 0.638415, 165, 新規, ハイポセテ
ィカルタンパク質 [Shigella flexneri] gi|5880472|gb
|aaD54665.1|AF097520#3の部分(40アミノ酸のうち44 %
一致) に類似 SEQ ID NO: 1517： 0.82528, 448, 新規, ShiA [Shigella flexneri] gi|5532447|gb|aaD44731.1|
AF141323#2のC-末端部分(73アミノ酸のうち49%一致) に
類似; TTGスタート SEQ ID NO: 1518： 0.075472, 107, 新規 SEQ ID NO: 1519： -0.587221, 494, 新規 SEQ ID NO: 1567： -0.283051, 414, 新規, TTGスター
ト SEQ ID NO: 1568： 0.021192, 152, 新規, GTGスタート SEQ ID NO: - ： 0.033871, 63, 新規, TTGスタート SEQ ID NO: 411： -0.575221, 340, 新規 SEQ ID NO: 412： 0.496, 51, 新規 SEQ ID NO: 413： -0.713974, 824, possible glucosyl
-transferase, glucosyl-transferases 例えば[Salmone
lla typhi] gi|7467230|pir||T30292 (366アミノ酸のう
ち72%一致) に類似 SEQ ID NO: 414： 0.095238, 64, 推定 ferric enteroc
helin エステラーゼ(partial), ferric enterochelin e
sterases 例えば[Salmonella enterica] gi| 2738250|g
b|aaC46181.1| (68アミノ酸のうち66%一致)のC-末端部
分に類似, TTGスタート SEQ ID NO: 415： -0.280645, 63, transposase, trans
posases 例えば[Shigella boydii] gi|2197010|gb|aaB6
1273.1| (167アミノ酸のうち100%一致) に類似 SEQ ID NO: 416： -0.108911, 102, possibleリプレッ
サー, InsAタンパク質 例えば[insertion sequence IS1
F] gi|124915|sp|P19767|ISA2#ECOLI (91アミノ酸のう
ち98%一致)に類似, GTGスタート SEQ ID NO: 417： -0.490164, 62, 新規 [推定 膜タン
パク質; IMP] SEQ ID NO: 418： -0.37, 51, 新規 SEQ ID NO: 419： -0.735659, 130, 新規, GTGスタート SEQ ID NO: 420： -0.62381, 43, 新規, センサー調節
因子タンパク質 HutT [Rhodobacter capsulatus] gi|10
75537|pir||A49938 (97アミノ酸のうち33%一致)に類似
(低い) SEQ ID NO: 421： -0.882353, 52, 新規 SEQ ID NO: 422： -0.729167, 73, 新規 SEQ ID NO: 423： -0.036842, 96, transposase (Orf
B), transposases 例えば[insertion sequenceIS629] g
i|7443863|pir||T00315 (295アミノ酸のうち98%一致)に
類似 SEQ ID NO: 424： -0.433333, 64, transposase (Orf
A), ハイポセティカルタンパク質 例えば[Escherichia
coli プラスミド pO157 insertion sequence IS629] gi
|7444868|pir||T00241 (108アミノ酸のうち96%一致)に
類似 SEQ ID NO: 425： -0.6728, 126, HecB-様タンパク質,
N-末端半分がhemolysinactivation タンパク質 HecB [N
eisseria meningitidis MC58] gi|7227016|gb|aaF4210
3.1| (181アミノ酸のうち34%一致)のN-末端部分に類似 SEQ ID NO: 426： -0.534445, 91, 新規 SEQ ID NO: 427： -0.372341, 142, 新規, tRNA-splici
ng endonuclease positive effector [fission yeast]
gi|7493527|pir||T40065 (531アミノ酸のうち22%一致)
の部分に類似(低い); また ハイポセティカルタンパク
質 例えば[Aquifexaeolicus] gi|7514764|pir||D70476
(271アミノ酸のうち24%一致)に類似(低い) SEQ ID NO: 428： -0.229139, 152, 新規, TTGスタート SEQ ID NO: 429： -0.721212, 364, 新規, ハイポセテ
ィカルタンパク質 例えばYbdN [Escherichia coli] gi|
3024984|sp|P77216|YBDN#ECOLI (396アミノ酸のうち58%
一致) に類似 SEQ ID NO: 430： -0.4, 249, 新規, ハイポセティカル
タンパク質 YbdM [Escherichia coli] gi|3024983|sp|P
77174|YBDM#ECOLI (212アミノ酸のうち56%一致)に類似 SEQ ID NO: 431： -0.385547, 257,転写調節因子, PerC
(BfpW) [Escherichia coli] gi|1172431|sp|P43475|PE
RC#ECOLI (83アミノ酸のうち25%一致)に類似 SEQ ID NO: 432： -0.49854, 138, 新規, exopolyphosp
hatase [Pseudomonas aeruginosa] gi|4200042|dbj|Baa
74460.1| (56アミノ酸のうち32%一致)に類似(低い) SEQ ID NO: 433： -0.133074, 258, 新規 SEQ ID NO: 434： 1.383019, 54, 新規, N-末端部分がB
fpM [Escherichia coli]gi|847983|gb|aaC44052.1| BFP
M#ECOLI (113アミノ酸のうち52%一致) に類似;またN-末
端部分が推定 transposase [Vibrio cholerae] gi|7467
523|pir||T09435 (68アミノ酸のうち55%一致) に類似;
C-末端部分がハイポセティカルタンパク質 [Escherichi
a coli O157:H7] gi|7649865|dbj|Baa94143.1| (62アミ
ノ酸のうち98%一致)の部分に類似 SEQ ID NO: 435： 0.16, 46, 新規, ハイポセティカル
タンパク質 [Pseudomonassyringae] gi|1196744|gb|aaA
88435.1| (50アミノ酸のうち34%一致)に類似(低い) SEQ ID NO: 436： 0.065714, 71, 新規, ハイポセティ
カルタンパク質 例えばorf29 [Escherichia coli] gi|6
009405|dbj|Baa84864.1| (131アミノ酸のうち40%一致);
L0013 [Escherichia coli] gi|3414881|gb|aaC31492.1
| (130アミノ酸のうち38%一致) に類似 SEQ ID NO: 437： -0.96087, 93, 新規 SEQ ID NO: 438： -0.462461, 326, 新規, ハイポセテ
ィカルタンパク質 例えばyfjP タンパク質 [Escherichi
a coli] gi|7449539|pir||B65042 (289アミノ酸のうち4
9%一致); yeePタンパク質 [Escherichia coli] gi|2495
624|sp|P76359|YEEP#ECOLI (183アミノ酸のうち95%一
致)に類似 SEQ ID NO: 439： -0.405691, 124, 推定 adhesin, 外
膜fluffingタンパク質[Escherichia coli] gi|7466262|
pir||G64964 (927アミノ酸のうち68%一致)に類似glyco
タンパク質 [Escherichia coli strain H10407] gi|530
5639|gb|aaD41751.1| (608アミノ酸のうち34%一致)に類
似(低い); Adhesin AIDA-I前駆体 [Escherichia coli
プラスミドpIB6] gi|543788|sp|Q03155|AIDA#ECOLI (67
8アミノ酸のうち23%一致)に類似 SEQ ID NO: 440： -0.14065, 124, 新規, ハイポセティ
カルタンパク質 YjDA [Escherichia coli] gi|731985|s
p|P16694|YJDA#ECOLI (793アミノ酸のうち32%一致)に類
似 SEQ ID NO: 441： 0.970589, 273, 新規, ハイポセティ
カルタンパク質 YjcZ [Escherichia coli] gi|731984|s
p|P39267|YJCZ#ECOLI (278アミノ酸のうち30%一致)に類
似, GTGスタート SEQ ID NO: 442： 0.125316, 80, 新規 SEQ ID NO: 443： 0.024615, 196, 新規 SEQ ID NO: 444： -0.242045, 617, 新規, ハイポセテ
ィカルタンパク質 例えばYfjQ [Escherichia coli] gi|
1723629|sp|P52132|YFJQ#ECOLI (271アミノ酸のうち73%
一致); YafZ [Escherichia coli] gi|2495487|sp|P7720
6|YAFZ#ECOLI (271アミノ酸のうち73%一致)に類似 SEQ ID NO: 445： -0.965741, 109, 新規, ハイポセテ
ィカルタンパク質 例えばYafK [Escherichia coli] gi|
2495486|sp|P75676|YAFX#ECOLI (144アミノ酸のうち71%
一致); YfjX [Escherichia coli] gi|1723636|sp|P5213
9|YFJX#ECOLI (137アミノ酸のうち75%一致)に類似 SEQ ID NO: 446： -0.635945, 218, 推定 DNA repair
タンパク質 (RadC family), 推定 RadC familyタンパク
質 例えばYkfG [Escherichia coli] gi|3025218|sp|Q47
685|YKFG#ECOLI (158アミノ酸のうち81%一致); YeeS [E
scherichia coli]gi|3025155|sp|P76362|YEES#ECOLI (1
48アミノ酸のうち98%一致)に類似 SEQ ID NO: 447： -0.957693, 105, 新規, ハイポセテ
ィカルタンパク質 YeeT [Escherichia coli] gi|302515
6|sp|P76363|YEET#ECOLI (73アミノ酸のうち97%一致)に
類似 SEQ ID NO: 448： 0.214754, 62, 新規, ハイポセティ
カルタンパク質 例えばYeeU [Escherichia coli] gi|30
25157|sp|P76364|YEEU#ECOLI (118アミノ酸のうち89%一
致); YfjZ [Escherichia coli] gi|1723638|sp|P52141|
YFJZ#ECOLI (98アミノ酸のうち66%一致)に類似, GTGス
タート SEQ ID NO: 449： -0.298065, 156, 新規, ハイポセテ
ィカルタンパク質 例えばL0007 [Escherichia coli] gi
|3414875|gb|aaC31486.1| (124アミノ酸のうち93%一
致); YeeV [Escherichia coli] gi|3025158|sp|P76365|
YEEV#ECOLI (124アミノ酸のうち87%一致); YkfI [Esche
richia coli] gi|3025213|sp|P77692|YKFI#ECOLI (112
アミノ酸のうち58%一致)に類似 SEQ ID NO: 450： 0.945946, 38, 新規, ハイポセティ
カルタンパク質 例えばL0008 [Escherichia coli] gi|3
414876|gb|aaC31487.1| (163アミノ酸のうち94%一致);
YeeW [Escherichia coli] gi|3025160|sp|P76366|YEEW#
ECOLI (55アミノ酸のうち65%一致)に類似 SEQ ID NO: 451： -0.110909, 56, 新規, ハイポセティ
カルタンパク質 例えばL0009 [Escherichia coli] gi|3
414877|gb|aaC31488.1| (65アミノ酸のうち87%一致)に
類似 SEQ ID NO: 452： -0.405085, 178, 新規, ハイポセテ
ィカルタンパク質 例えばL0010 [Escherichia coli] gi
|3414878|gb|aaC31489.1| (111アミノ酸のうち81%一
致); ydiA [プラスミド ColIb-P9] gi|4512489|dbj|Baa
75138.1| (265アミノ酸のうち37%一致); L0012 [Escher
ichia coli] gi|3414880|gb|aaC31491.1| (61アミノ酸
のうち80%一致)に類似 SEQ ID NO: 453： -0.335897, 79, 新規 SEQ ID NO: 454： 0.984375, 65, 推定 インテグラー
ゼ, インテグラーゼ 例えば[Escherichia coli prophag
e e14] gi|3024035|sp|P75969|INTE#ECOLI (372アミノ
酸のうち46%一致)に類似 SEQ ID NO: 455： 0.088596, 115, 推定 excisionase,
excisionase [bacteripohage P21] gi|139674|sp|P270
79|VXIS#BPP21 (73アミノ酸のうち31%一致)に類似 SEQ ID NO: 456： 0.123529, 69, 新規, GTGスタート SEQ ID NO: 457： -0.905494, 92, 新規, TTGスタート SEQ ID NO: 458： -0.403175, 127, 新規, ハイポセテ
ィカルタンパク質 例えばYdfA [Escherichia coli] gi|
140584|sp|P29008|YDFA#ECOLI (49アミノ酸のうち91%一
致)に類似 SEQ ID NO: 459： 0.010435, 116, 推定 phage リプレ
ッサー, リプレッサー[Escherichia col Rac prophag
e] gi|3025101|sp|P76062|RACR#ECOLI (158アミノ酸の
うち91%一致)に類似 SEQ ID NO: 460： -0.445312, 513, 新規, YdaS [Esch
erichia coli] gi|3025102|sp|P76063|YDAS#ECOLI (94
アミノ酸のうち84%一致)に類似 SEQ ID NO: 461： -0.04875, 81, 新規, YdaT [Escheri
chia coli] gi|3183265|sp|P76165|YDFX#ECOLI (83アミ
ノ酸のうち31%一致)に類似 SEQ ID NO: 462： -0.425233, 643, 新規,複製 termina
tion タンパク質 DnaT (prepriming タンパク質 I) [Es
cherichiacoli] gi|1361001|pir||S56589 のC-末端部分
(85アミノ酸のうち50%一致)に類似 SEQ ID NO: 463： -0.448868, 531, 推定 複製 タンパ
ク質,複製タンパク質 例えばタンパク質14[Bacteriopha
ge phi-80] gi|137937|sp|P14814|VG14#BPPH8 (129アミ
ノ酸のうち47%一致)に類似, GTGスタート SEQ ID NO: 464： 0.055688, 502, 新規, YdaW [Escher
ichia coli] gi|3025105|sp|P76066|YDAW#ECOLI (143ア
ミノ酸のうち56%一致)に類似 SEQ ID NO: 465： -0.024348, 116, 新規, GTGスタート SEQ ID NO: 466： -0.331818, 89, 新規, Gp57 [Bacte
riophage N15] gi|7459176|pir||T13144 (78アミノ酸の
うち69%一致)に類似, GTGスタート 467： -0.239801, 202, 新規, ハイポセティカルタンパ
ク質 例えば[Bacteriophage VT2-Sa] gi|5881670|dbj|B
aa84361.1| (92アミノ酸のうち91%一致)に類似,GTGスタ
ート SEQ ID NO: 468： -0.297006, 168, 新規 SEQ ID NO: 469： -0.163566, 130, 新規, ハイポセテ
ィカルタンパク質 例えばEa22 [Bacteriophage lambda]
gi|137663|sp|P03756|VE22#LAMBD (108アミノ酸のうち
39%一致)に類似, GTGスタート SEQ ID NO: 470： -0.442375, 860, 新規 SEQ ID NO: 471： -0.447707, 110, 新規, N-末端部分
がハイポセティカルタンパク質 例えばb2363 [Escheric
hia coli] gi|7451977|pir||H65009 (95アミノ酸のうち
51%一致)に類似, C-末端部分が ハイポセティカルタン
パク質 例えば[Bacteriophage 933W] gi|4585382|gb|aa
D25410.1|AF125520#5 (75アミノ酸のうち43%一致)に類
似 SEQ ID NO: 472： -0.339655, 233, 新規 SEQ ID NO: 473： -0.377251, 212, prophage maintena
nceタンパク質, Hok/Geffamily 例えばMokW [Bacteriop
hage 933W] gi|4585453|gb|aaD25481.1|AF125520#76 (7
0アミノ酸のうち90%一致)に類似 SEQ ID NO: 474： 0.057965, 227, 新規, QD1 [Bacter
iophage N15] gi|2564084|gb|aaB81659.1| (64アミノ酸
のうち31%一致)に類似 SEQ ID NO: 475： -0.939706, 69, 新規, b1560 [Esch
erichia coli] gi|1742555|dbj|Baa15259.1| (348アミ
ノ酸のうち82%一致); ハイポセティカルタンパク質 A
[phage P1] gi|732234|sp|Q06262|YORA#BPP1 (314アミ
ノ酸のうち26%一致)に類似(also to Orf19 (phi83) ),
GTGスタート SEQ ID NO: 476： -0.161714, 176, 推定 crossover ju
nction endodeoxyribonuclease, Gp67 [Bacteriophage
HK97] gi|6901639|gb|aaF31142.1| (110アミノ酸のうち
59%一致); crossover junction endodeoxyribonuclease
s Rus [Escherichia coli cryptic lambdoid prophage
DLP12] (107アミノ酸のうち41%一致) gi|2507117|sp|P
40116|RUS#ECOLI in (110アミノ酸のうち59%一致)に類
似 SEQ ID NO: 477： -0.277615, 1158, 推定 antitermina
tion タンパク質, antitermination タンパク質 例えば
タンパク質Q[Escherichia coli] gi|1742554|dbj|Baa15
258.1| (273アミノ酸のうち39%一致)に類似 SEQ ID NO: 478： -0.279397, 200, 新規, GTGスタート SEQ ID NO: 479： -0.658542, 440, 新規, GTGスタート SEQ ID NO: 480： -0.259551, 90, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage VT2-Sa] gi|588
1634|dbj|Baa84325.1| (644アミノ酸のうち73%一致)に
類似 SEQ ID NO: 481, ECs1125:1209796-1209978, -0.07833
3, 61, 新規, ハイポセティカルタンパク質 [Bacteriop
hage 933W] gi|4499806|emb|CAB39305.1| (59アミノ酸
のうち67%一致)に類似 SEQ ID NO: 482 -0.877248, 190, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage VT2-Sa] gi|5
881635|dbj|Baa84326.1| (89アミノ酸のうち78%一致)に
類似 483： -0.436667, 61, 推定 holin タンパク質, holin
タンパク質 例えばSタンパク質 [Bacteriophage VT2-S
a] gi|5881636|dbj|Baa84327.1| (71アミノ酸のうち94%
一致)に類似 SEQ ID NO: 245： -0.375688, 437, 新規, YdfR [Esch
erichia coli] gi|3183262|sp|P76160|YDFR#ECOLI (74
アミノ酸のうち47%一致)に類似 SEQ ID NO: 246： -0.447872, 95, 推定 endolysin, e
ndolysins 例えばRタンパク質 [Bacteriophage 933W] g
i|4585422|gb|aaD25450.1|AF125520#45 (177アミノ酸の
うち97%一致)に類似 SEQ ID NO: 247： -0.294175, 104, 推定 antiリプレッ
サー タンパク質,推定 antiリプレッサータンパク質 [B
acteriophage 933W] gi|4585423|gb|aaD25451.1|AF1255
20#46 と同じ; antiリプレッサー タンパク質 Ant [Bac
teriophageP22] gi|131843|sp|P03037|RANT#BPP22 (189
アミノ酸のうち49%一致)に類似 SEQ ID NO: 248： -0.781579, 115, endoペプチダーゼ
(host cell lysis), endoペプチダーゼ 例えばRz[Bact
eriophage VT2-Sa] gi|5881639|dbj|Baa84330.1|(155ア
ミノ酸のうち80%一致)に類似 SEQ ID NO: 249： -0.371015, 208, リポタンパク質 Rz
1precursor, リポタンパク質 Rz1前駆体 例えば[Bacter
iophage 933W]gi|540738|pir||JN0750 (59アミノ酸のう
ち52%一致); [phage lambda] gi|4585425|gb|aaD25453.
1|AF125520#48 (59アミノ酸のうち76%一致)に類似 SEQ ID NO: 250： -0.407368, 96, 新規 SEQ ID NO: 251： 0.416667, 73, 新規, ハイポセティ
カルタンパク質 [Bacteriophage VT2-Sa] gi|5881640|d
bj|Baa84331.1| (45アミノ酸のうち73%一致)に類似 SEQ ID NO: 252： -0.590526, 96, 新規 SEQ ID NO: 253： -0.644516, 156, 新規, ハイポセテ
ィカルタンパク質 [Escherichia coli] gi|1778472|gb|
aaB40755.1| (53アミノ酸のうち84%一致)に類似 SEQ ID NO: 254： -0.557587, 258, 推定 DNase, 推定
DNAse [Bacteriophage phi-31] gi|1107475|emb|Caa625
87.1| (85アミノ酸のうち28%一致)に類似 SEQ ID NO: 255： -0.615069, 74, 推定 terminase sma
ll subunit, terminasesmall subunit [Bacillus subti
lis PBSX phage] gi|1722886|sp|P39785|XTMA#BACSU (5
7アミノ酸のうち42%一致)に類似, GTGスタート SEQ ID NO: 256： -0.595775, 72, 推定 large termina
se subunit, ハイポセティカルタンパク質, 例えばphag
e D3 terminase-様 タンパク質 [Haemophilus influenz
ae] gi|6739656|gb|aaF27357.1|AF198256#11 (472アミ
ノ酸のうち22%一致)に類似; 推定 large terminase sub
unit [Bacteriophage A2] gi|3947452|emb|Caa07103.1|
(456アミノ酸のうち25%一致)に類似 SEQ ID NO: 257： -0.24127, 64, 推定 major head タ
ンパク質/prohead プロテイナーゼ, N-末端半分が推定
prohead プロテアーゼ 例えばGp4 [BacteriophageHK97]
gi|1722780|sp|P49860|VP4#BPHK7 (136アミノ酸28のう
ち%一致)に類似,C-末端半分がmajor headタンパク質 例
えば[Bacteriophage L5] gi|465114|sp|Q05223|VG17#BP
ML5 (280アミノ酸のうち23%一致)に類似, GTGスタート SEQ ID NO: 258： -0.248333, 61, 推定 portalタンパ
ク質, portalタンパク質例えば[Bacteriophage HK022]
gi|6863114|gb|aaF30355.1|AF069308#3 (351アミノ酸の
うち26%一致)に類似 SEQ ID NO: 259： -0.338496, 227, 新規, 新規なタン
パク質 [Haemophilus influenzae] gi|6739659|gb|aaF2
7360.1|AF198256#14 (21アミノ酸のうち71%一致)に類
似, GTGスタート SEQ ID NO: 260： -0.500383, 262, 推定 head-tail ad
apotor,推定 head-tail adaptors 例えば[Bacteriophag
e HK97] gi|6901597|gb|aaF31100.1| (111アミノ酸のう
ち45%一致)に類似 SEQ ID NO: 261： -0.665942, 139, 新規, ハイポセテ
ィカルphage タンパク質例えばGp10 [Bacteriophage HK
97] gi|6901598|gb|aaF31101.1| (148アミノ酸のうち75
%一致)に類似 SEQ ID NO: 262： 0.008989, 90, 新規,Gp11 [Bacterio
phage HK97] gi|6901599|gb|aaF31102.1| (113アミノ酸
のうちSEQ ID NO: 49%一致)に類似 SEQ ID NO: 263： -0.544444, 55, 推定 major tail su
bunit, major tail subunit [Bacteriophage HK97] gi|
6901588|gb|aaF31091.1|AF069529#4 (234アミノ酸のう
ち66%一致)に類似 SEQ ID NO: 264： -0.273771, 123, 推定 tail assembl
y chaperone, tail assembly chaperon例えばp14 [Bact
eriophage HK97] gi|6901600|gb|aaF31103.1| (124アミ
ノ酸のうち62%一致)に類似 SEQ ID NO: 265： -0.027711, 84, 推定 tailタンパク
質[phage tail タンパク質], [Bacteriophage HK97] gi
|6901601|gb|aaF31104.1|のC-末端部分Gp14(90アミノ酸
のうち60%一致)に類似, probably produced by transla
tional frameshift SEQ ID NO: 266： -0.755556, 91, 推定 tail length t
ape measureタンパク質(interrupted), tail length ta
pe measureタンパク質 例えば[Bacteriophage HK97] gi
|6901589|gb|aaF31092.1|AF069529#5のN-末端部分(137
アミノ酸のうち81%一致)に類似 SEQ ID NO: 267： -0.881667, 61, 推定 tail length t
ape measure タンパク質, tail length tape measure
タンパク質 例えば[Bacteriophage HK97] gi|6901589|g
b|aaF31092.1|AF069529#5のC-末端部分(939アミノ酸の
うち48%一致)に類似, probably disrupted by frameshi
ft SEQ ID NO: 268： 0.743396, 54, 推定 minor tail タ
ンパク質, minor tail タンパク質 例えばGpM [Bacteri
ophage lambda] gi|138845|sp|P03737|VMTM#LAMBD(110
アミノ酸のうち43%一致)に類似, GTGスタート SEQ ID NO: 269： -0.476879, 174, 推定 minor tail
タンパク質, minor tailタンパク質 例えばGpL [Bacte
riophage lambda] gi|138844|sp|P03738|VMTL#LAMBD (2
32アミノ酸のうち76%一致)に類似 SEQ ID NO: 270： -0.315668, 218, 推定 調節タンパク
質, 調節タンパク質 Mnt[Bacteriophage P22] gi|13313
8|sp|P03049|RMNT#BPP22 73アミノ酸(のうち34%一致)に
類似 SEQ ID NO: 271： -0.295775, 72, 推定 antiリプレッ
サー タンパク質, C-末端部分が antiリプレッサータン
パク質 例えばAnt[Bacteriophage P22] gi|131843|sp|P
03037|RANT#BPP22 (171アミノ酸のうち84%一致)に類似,
N-末端部分が ハイポセティカルphageタンパク質 例え
ばGp30 [Bacteriophage N15] gi|7521545|pir||T13116
(175アミノ酸のうち35%一致)に類似 SEQ ID NO: 272： -0.322449, 99, 推定 tail assembly
タンパク質, tail assembly タンパク質 例えばGpK [B
acteriophage lambda] gi|139638|sp|P03729|VTAK#LAMB
D (196アミノ酸のうち86%一致)に類似 SEQ ID NO: 273： -1.166667, 49, 推定 tail assembly
タンパク質, tail assembly タンパク質 例えばGpI [B
acteriophage lambda] gi|139637|sp|P03730|VTAI#LAMB
D (64アミノ酸のうち64%一致)に類似 SEQ ID NO: 274： -0.734113, 300, 推定 secreted eff
ector タンパク質, secreted effectorタンパク質opA
[Salmonella dublin] gi|5669806|gb|aaD46479.1|AF121
227#1 (587アミノ酸のうち31%一致)に類似 SEQ ID NO: 275： -0.469565, 484, 新規, C-末端部分
が cytotoxic necrotizing factor type 2 [Escherichi
a coli] gi|1073353|pir||A55260 (244アミノ酸のうち3
1%一致)に類似(N-末端は新規なタンパク質 [P. falcipa
rum] に類似(低い)) SEQ ID NO: 276： -0.447191, 90, 新規 SEQ ID NO: 277： -0.883696, 93, 新規 [ハイポセテ
ィカル膜タンパク質; IMP], ハイポセティカルタンパク
質 例えばb0362 [Escherichia coli] gi|7466098|pir||
B64764 (79アミノ酸のうち50%一致)に類似, [hemin レ
セプター前駆体に部分的に類似] SEQ ID NO: 278： -0.825352, 72, transposase (OrfB)
タンパク質 (insertionsequence IS2), ハイポセティ
カルタンパク質 例えば[insertion sequence IS2] gi|1
40808|sp|P19777|YI22#ECOLI (301アミノ酸のうち98%一
致)に類似, GTGスタート SEQ ID NO: 279： -, 79, 新規, [推定 transposase
(OrfA) ] ハイポセティカルタンパク質 [insertion seq
uence IS2] gi|140806|sp|P19776|YI21#ECOLI (53アミ
ノ酸のうち100%一致)に類似 SEQ ID NO: 280 -0.735135, 149, 新規, ハイポセティ
カルタンパク質 [Salmonella typhimurium LT2] gi|696
0367|gb|aaF33527.1| (37アミノ酸のうち72%一致)に類
似 SEQ ID NO: 281： -0.217714, 176, 新規 SEQ ID NO: 282： -1.381667, 61, 新規, Yop effector
YopM [Yersinia enterocolitica] gi|4324334|gb|aaD1
6811.1| (171アミノ酸のうち25%一致)に類似, (also we
akly to IpaH) SEQ ID NO: 283： -0.215789, 58, 新規, TTGスタート SEQ ID NO: 284： -0.530738, 245, 推定 インテグラー
ゼ, インテグラーゼ 例えば[Shigella dysenteriae] gi
|6759954|gb|aaF28112.1|AF153317#4 (389アミノ酸のう
ち31%一致)に類似 SEQ ID NO: 285： -0.205833, 241, 推定 DNA結合 タン
パク質; 推定 DNA結合タンパク質 (ORF88) [Bacterioph
age P4] gi|140147|sp|P12552|Y9K#BPP4 (53アミノ酸の
うち45%一致)に類似, GTGスタート SEQ ID NO: 286： -1.10199, 202, 新規ＳＥＱ ＩＤ
ＮＯ： ２８７： -0.534375, 65, 推定 cell division
リプレッサー, cell division リプレッサー Icd [ent
erobacteria phage P1] gi|4261623|gb|aa酸D13923.1|S
61175#1 (45アミノ酸のうち42%一致)に類似 SEQ ID NO: 288： -0.325, 145, 新規 SEQ ID NO: 289： -0.088, 51, 新規 SEQ ID NO: 290： -0.079937, 320, 新規 SEQ ID NO: 291： -0.191011, 90, 新規 SEQ ID NO: 292： -0.281545, 635, 新規 SEQ ID NO: 293： -0.397973, 297, 新規 SEQ ID NO: 294： -0.965741, 109, 新規 SEQ ID NO: 295： 0.008475, 60, 新規 SEQ ID NO: 296： -0.431081, 149, 新規 SEQ ID NO: 297： 0.039437, 72, 推定 single strande
d DNA-結合タンパク質,single stranded DNA-bindingタ
ンパク質 例えば[Thermotoga maritima] gi|7439946|pi
r||H72354 (96アミノ酸のうち35%一致)に類似 SEQ ID NO: 298： -0.449153, 178, 推定 転写 アクチ
ベーター, eaeA/bfpA [Escherichia coli] gi|1172431|
sp|P43475|PERC#ECOLIの PerC (BfpW)転写アクチベータ
ー(89アミノ酸のうち39%一致)に類似 SEQ ID NO: 299： -0.283069, 190, 新規 SEQ ID NO: 300： -0.520779, 155, 推定 major head
タンパク質, major headタンパク質 例えばphage phi-C
31 gp36-様 タンパク質 [Haemophilus influenzae] gi|
6739663|gb|aaF27364.1|AF198256#18 (AF198256) (584
アミノ酸のうち56%一致)に類似 SEQ ID NO: 301： 0.198361, 62, 推定 prohead プロテ
アーゼ, prohead プロテアーゼ 例えばphage phi-C31 g
p35-様 タンパク質 [Haemophilus influenzae] gi|6739
662|gb|aaF27363.1|AF198256#17 (161アミノ酸のうち60
%一致)に類似 SEQ ID NO: 302： 0.183505, 98, 推定 head portal タ
ンパク質, head portalタンパク質 例えばphage phi-10
5 ORF25-様 タンパク質 [Haemophilus influenzae]gi|6
739661|gb|aaF27362.1|AF198256#16 (403アミノ酸のう
ち63%一致)に類似 SEQ ID NO: 303： -0.097403, 78, 推定 head-tail ada
ptor, head-tail adaptors 例えば[Bacteriophage HK9
7] gi|6901597|gb|aaF31100.1| (112アミノ酸のうち47%
一致)に類似 SEQ ID NO: 304： -0.730597, 269, 新規, ハイポセテ
ィカルタンパク質 [Haemophilus influenzae] gi|67396
59|gb|aaF27360.1|AF198256#14 (98アミノ酸のうち45%
一致); ハイポセティカルタンパク質 30 [Bacillus pha
ge phi-105] gi|7459182|pir||T13519 (90アミノ酸のう
ち26%一致)に類似 SEQ ID NO: 305： -0.554049, 569, 新規, ハイポセテ
ィカルタンパク質 例えば[Haemophilus influenzae] gi
|6739658|gb|aaF27359.1|AF198256#13 (115アミノ酸の
うち54%一致)に類似 SEQ ID NO: 306： -0.527872, 715, 新規 SEQ ID NO: 307： -0.766567, 336, 推定 terminase sm
all subunit, ハイポセティカルタンパク質, genetic i
sland 1 [Haemophilus influenzae] gi|6739657|gb|aaF
27358.1|AF198256#12 (112アミノ酸のうち64%一致)に類
似; 推定 terminase small subunit [Streptococcus th
ermophilus bacteriophage Sfi21] gi|5230826|gb|aaD4
1028.1|AF112470#3 (98アミノ酸のうち29%一致)に類似 SEQ ID NO: 308： -0.398762, 405, 推定 terminase la
rge subunit, terminaselarge subunits 例えば[Haemop
hilus influenzae] gi|6739656|gb|aaF27357.1|AF19825
6#11 (550アミノ酸のうち69%一致)に類似, TTGスタート SEQ ID NO: 309： 0.25969, 130, 新規 SEQ ID NO: 310： -0.52549, 154, 新規, GTGスタート SEQ ID NO: 311： -0.157219, 188, インテグラーゼ,
インテグラーゼ 例えば[Bacteriophage P21] gi|138558
|sp|P27077|VINT#BPP21 (380アミノ酸のうち98%一致)に
類似, (lambdaインテグラーゼに類似) SEQ ID NO: 312： 0.063889, 217, excisionase, excis
ionases 例えば[Bacteriophage P21] gi|139674|sp|P27
079|VXIS#BPP21 (78アミノ酸のうち98%一致)に類似 SEQ ID NO: 313： -0.793334, 646, 推定 複製タンパク
質, 複製タンパク質 例えばGpO [Bacteriophage lambd
a] gi|215150|gb|aaA96584.1| (261アミノ酸のうち69%
一致)に類似 SEQ ID NO: 314： -0.266292, 90, 複製 タンパク質,
複製タンパク質 例えばGpP [Bacteriophage lambda] gi
|4499785|emb|CAB39284.1| (233アミノ酸のうち98%一
致)に類似 SEQ ID NO: 315： -0.19875, 81, 推定 Ren タンパク質
(protection from Rex-依存性 exclusion), Ren タン
パク質 例えば[Bacteriophage lambda] gi|139473|sp|P
03761|VREN#LAMBD (92アミノ酸のうち90%一致)に類似 SEQ ID NO: 316： 0.06375, 81, integral membrane dr
ug resistance タンパク質 EmrE, ethidium efflux タ
ンパク質 EmrE (methyl viologen resistance タンパク
質 C) [E. coli] gi|127565|sp|P23895|EMRE#ECOLI (11
0アミノ酸のうち98%一致)に類似, belongs to the smal
l multidrug resistance (Smr) タンパク質 family SEQ ID NO: 317： -0.018342, 568, 新規, ハイポセテ
ィカルタンパク質 YbcK[Escherichia coli] gi|2495549
|sp|P77698|YBCK#ECOLI (508アミノ酸のうち99%一致);
推定 インテグラーゼ [Bacteriophage A118] gi|119632
4|gb|aaB51416.1| (109アミノ酸のうち31%一致)に類似 SEQ ID NO: 318： -0.248578, 423, 新規, ハイポセテ
ィカルタンパク質 YbcN [Escherichia coli cryptic la
mbdoid prophage DLP12] gi|2495551|sp|Q47269|YBCN#E
COLI (151アミノ酸のうち92%一致)に類似, GTGスタート SEQ ID NO: 319： -0.218478, 93, 新規, NinE [Bacter
iophage 82] gi|3024190|sp|Q37871|NINE#BP82と同じ SEQ ID NO: 320： -0.159512, 206, 新規, YbcO [Esche
richia coli cryptic prophage DLP12] gi|2495553|sp|
Q47271|YBCO#ECOLI (96アミノ酸のうち97%一致);Gp66
[Bacteriophage HK97] gi|6901638|gb|aaF31141.1| (95
アミノ酸のうち68%一致)に類似 SEQ ID NO: 321： -0.289344, 245, crossover junctio
n endodeoxyribonuclease, crossover junction endod
eoxyribonucleases Rus 例えば[Escherichia coli bact
eriophage 82] gi|2498868|sp|Q37873|RUS#BP82 (120ア
ミノ酸のうち95%一致)に類似, GTGスタート SEQ ID NO: 322： -0.103759, 134, 推定 antiterminat
ionタンパク質, antitermination タンパク質 例えばQ
[Bacteriophage 82] gi|132277|sp|P13870|RegQ#BP82
(229アミノ酸のうち98%一致)に類似 SEQ ID NO: 323： -0.622936, 219, 推定 holin, 推定
holinタンパク質 [Bacteriophage PS3] gi|3676074|emb
|Caa09700.1| (103アミノ酸のうち72%一致)に類似, TTG
スタート SEQ ID NO: 324： -0.662162, 149, 推定 endolysin (l
yzozyme), endolysins例えば[Bacteriophage HK97] gi|
6901642|gb|aaF31145.1| (158アミノ酸のうち95%一致)
に類似

【００１９】２）有意なホモロジーを有する機能等は新
規なタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 325： -0.109639, 84, 推定 endoペプチダ
ーゼ (host cell lysis),ハイポセティカルタンパク質
gp15 [Bacteriophage PS119] gi|3676087|emb|Caa0971
1.1| (155アミノ酸のうち83%一致); endoペプチダーゼ
例えば[Bacteriophage lambda] gi|67522|pir||APBPML
(153アミノ酸のうち59%一致)に類似 SEQ ID NO: 326： -0.749881, 422, 推定 リポタンパク
質 Rz1前駆体, リポタンパク質 Rz1前駆体 例えば[Bact
eriophage lambda]アミノ酸のうち53%類似 SEQ ID NO: 327： -0.631149, 2794, 新規 SEQ ID NO: 328： -0.122951, 62, 新規 [ハイポセテ
ィカル膜タンパク質; IMP] SEQ ID NO: 329： -0.232456, 115, 新規 SEQ ID NO: 330： 0.222857, 71, 推定 terminase larg
e subunit, terminase large subunits 例えば[Bacteri
ophage WO] gi|6723224|dbj|Baa89621.1| (641アミノ酸
のうち26%一致); 例えば[Bacteriophage N15] gi|74445
79|pir||T13088 (630アミノ酸のうち25%一致)に類似 SEQ ID NO: 331： -0.754198, 132, 新規 SEQ ID NO: 332： -0.709589, 220, 推定 portalタンパ
ク質,推定 portalタンパク質 [Wolbachia sp. wKue]gi|
6723246|dbj|Baa89642.1| (294アミノ酸のうち23%一致)
に類似, GTGスタート SEQ ID NO: 333： -0.319445, 73, 新規 SEQ ID NO: 334： -0.243617, 95, 推定 プロテアーゼ/
scaffold タンパク質, ClpP プロテアーゼ 例えば[Bact
eriophage D3] gi|5059251|gb|aaD38956.1| (218アミノ
酸のうち35%一致)に部分的に類似; 推定 scaffolding
タンパク質 [Streptococcus thermophilus bacteriopha
ge DT1] gi|4530143|gb|aaD21883.1| (201アミノ酸のう
ち30%一致)に類似 SEQ ID NO: 335： -0.664384, 74, 新規, TTGスタート SEQ ID NO: 336： -0.528708, 210, 新規 SEQ ID NO: 1570： -0.651901, 448, minor tail タン
パク質 例えばタンパク質Z [Bacteriophage N15] gi|75
21219|pir||T13097 (192アミノ酸のうち52%一致); GpZ
[Bacteriophage lambda] gi|138849|sp|P03731|VMTZ#LA
MBD (192アミノ酸のうち49%一致)に類似 SEQ ID NO: 1030： 0.101176, 511, 推定 minor tail c
omponent, minor tailタンパク質 例えばタンパク質 U
[Bacteriophage N15] gi|7444588|pir||T13098 (129ア
ミノ酸のうち49%一致); GpU [Bacteriophage lambda] g
i|138847|sp|P03732|VMTU#LAMBD (129アミノ酸のうち49
%一致)に類似 SEQ ID NO: 1031： -0.163804, 164, major tail compo
nent, major tail タンパク質 例えばタンパク質 V [Ba
cteriophage N15] gi|7444589|pir||T13099 (244アミノ
酸のうち62%一致); GpV [Bacteriophage lambda] gi|13
8848|sp|P03733|VMTV#LAMBD (246アミノ酸のうち55%一
致)に類似 SEQ ID NO: 1032： -0.270741, 271, minor tail compo
nent, minor tail タンパク質 例えばGpG [Bacteriopha
ge lambda] gi|138842|sp|P03734|VMTG#LAMBD (109アミ
ノ酸のうち33%一致)に類似 SEQ ID NO: 1033： 0.038403, 264, 推定 minor tail c
omponent, minor tailタンパク質 例えばGpT [Bacterio
phage lambda] gi|138846|sp|P03735|VMTT#LAMBD (104
アミノ酸のうち39%一致)に類似, probably produced by
translationalframeshift SEQ ID NO: 1034： -0.454546, 210, 推定tail length
tape measureタンパク質前駆体, tail length tape me
asureタンパク質前駆体 例えばGpH [Bacteriophage lam
bda] gi|138843|sp|P03736|VMTH#LAMBD (822アミノ酸の
うち25%一致)に類似 SEQ ID NO: 1035： -0.041442, 445, 推定 minor tail
タンパク質, minor tailタンパク質 例えばGpM [Bacter
iophage lambda] gi|138845|sp|P03737|VMTM#LAMBD (10
8アミノ酸のうち55%一致)に類似 SEQ ID NO: 1036： -0.442976, 841, 推定 minor tail
タンパク質, minor tailタンパク質 例えばGpL [Bacter
iophage lambda] gi|138844|sp|P03738|VMTL#LAMBD (23
2アミノ酸のうち93%一致)に類似 SEQ ID NO: 1037： -0.153648, 234, 推定 tail assemb
ly タンパク質, tail assembly タンパク質 例えばGpK
[Bacteriophage lambda] gi|139638|sp|P03729|VTAK#LA
MBD (199アミノ酸のうち97%一致)に類似 SEQ ID NO: 1038： 0.21129, 187, 推定 tail assembly
タンパク質, tail assembly タンパク質 例えばGpI [B
acteriophage lambda] gi|139637|sp|P03730|VTAI#LAMB
D (215アミノ酸のうち80%一致)に類似 SEQ ID NO: 1039： -0.061353, 208, 推定 host specif
icity タンパク質, hostspecificity タンパク質 例え
ばGpJ [Bacteriophage lambda] gi|138412|sp|P03749|V
HSJ#LAMBD (1136アミノ酸のうち88%一致)に類似 SEQ ID NO: 1040： -0.166719, 1269, 推定 外膜タンパ
ク質前駆体, 外膜タンパク質 Lom前駆体 例えば[propha
ge P-EibA] gi|7532789|gb|aaF63231.1|AF151091#2 (19
9アミノ酸のうち72%一致)に類似 SEQ ID NO: 1041： -0.41948, 540, 推定 tail fiber
タンパク質, tail fiberタンパク質 例えば[Bacterioph
age 933W] gi|4585436|gb|aaD25464.1|AF125520#59 (27
7アミノ酸のうち67%一致)に類似 SEQ ID NO: 1042： 0.009016, 123, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage 933W] gi|458
5437|gb|aaD25465.1|AF125520#60 (102アミノ酸のうち9
8%一致)に類似 SEQ ID NO: 1043： 0.422222, 190, 新規, ハイポセテ
ィカルタンパク質 [Salmonella typhimurium LT2] gi|6
960367|gb|aaF33527.1| (314アミノ酸のうち55%一致)に
類似 SEQ ID NO: 1044： -0.17033, 183, 新規 SEQ ID NO: 1045： -0.29785, 94, 新規 SEQ ID NO: 1046： -0.139896, 387, 新規 SEQ ID NO: 1047： -0.09284, 853, 新規 SEQ ID NO: 1048： -0.12362, 327, 新規, secreted ef
fector タンパク質opA,[Salmonella dublin] gi|566980
6|gb|aaD46479.1|AF121227#1 (296アミノ酸のうち24%一
致)に類似, ハイポセティカルタンパク質 例えばYjBI
[Escherichia coli] gi|418540|sp|P32690|YJBI#ECOLI
(183アミノ酸のうち26%一致)に類似, weakly SEQ ID NO: 1049： -0.341696, 284, 新規 [ハイポセ
ティカル膜タンパク質; IMP] SEQ ID NO: 1050： 0.074894, 236, 推定 PTS 輸送 タ
ンパク質, 推定 輸送タンパク質 例えばSgaT [Escheric
hia coli] gi|2851673|sp|P39301|SGAT#ECOLI (440アミ
ノ酸のうち38%一致)に類似 1051： -0.083945, 219, 推定 PTS system enzyme II,p
hosphotransferase system enzymes IIB 例えば[Escher
ichia coli] gi|732028|sp|P39302|PTXB#ECOLI (99アミ
ノ酸のうち28%一致)に類似 SEQ ID NO: 1052： 0.436468, 437, 新規 SEQ ID NO: 1053： -0.546947, 263, 新規, GTGスター
ト SEQ ID NO: 1054： -0.377489, 463, 新規 SEQ ID NO: 133： -0.3865, 401, unkown SEQ ID NO: 134： -0.199834, 606, 推定 インテグラー
ゼ インテグラーゼ 例えば[Bacteriophage HK022] gi|1
38560|sp|P16407|VINT#BPHK0 (321アミノ酸のうち27%一
致)に類似 SEQ ID NO: 135： -0.420689, 146, 新規 SEQ ID NO: 136： -0.487755, 99, 新規 SEQ ID NO: 137： -0.331236, 462, 新規, ハイポセテ
ィカルタンパク質 例えばYdfD [Escherichia coli] gi|
140587|sp|P29010|YDFD#ECOLI (63アミノ酸のうち63%一
致)に類似 SEQ ID NO: 138： -0.780214, 188, 推定 cell divisio
n inhibition, dicB [Escherichia coli] gi|2507009|s
p|P09557|DICB#ECOLI (62アミノ酸のうち54%一致)に類
似 SEQ ID NO: 139： -0.17888, 787, 新規, TTG スタート SEQ ID NO: 140： 0.226, 51, 新規 SEQ ID NO: 141： -0.445312, 513, 新規 SEQ ID NO: 142： 0.010435, 116, 新規 SEQ ID NO: 143： -0.395489, 134, 新規, YdfB [Esche
richia coli] gi|140585|sp|P29009|YDFB#ECOLI (41ア
ミノ酸のうち100%一致)に類似 SEQ ID NO: 144： -0.538835, 104, 新規, YdfA [Esche
richia coli] gi|140584|sp|P29008|YDFA#ECOLI (51ア
ミノ酸のうち100%一致)と同じ SEQ ID NO: 145： -0.684191, 273, 新規, TTGスタート SEQ ID NO: 146： -0.275807, 249, 新規, ハイポセテ
ィカルタンパク質 例えばyacB [プラスミド ColIb-P9]
gi|4512441|dbj|Baa75090.1| に92アミノ酸のうち35%類
似 SEQ ID NO: 147： -0.519277, 84, 新規 SEQ ID NO: 148： -0.448958, 97, 推定 調節 タンパク
質, に類似 推定 調節タンパク質 [Salmonella typhimu
rium] gi|7467281|pir||T03008 (108アミノ酸のうち30%
一致); DicA [Escherichia coli] gi|118631|sp|P06966
|DICA#ECOLI (108アミノ酸のうち27%一致)に類似 SEQ ID NO: 149： -0.025758, 67, 新規 SEQ ID NO: 150： 0.918487, 120, 新規, YdaT [Escher
ichia coli] gi|3025103|sp|P76064|YDAT#ECOLI (141ア
ミノ酸のうち31%一致)に類似 SEQ ID NO: 151： -0.246963, 429, 新規 SEQ ID NO: 152： 0.574468, 48, 新規 SEQ ID NO: 153： 0.214286, 92, 推定 DNA複製タンパ
ク質, DnaC homolog [Escherichia coli] gi|7429001|p
ir||C64886 (248アミノ酸のうち79%一致)； DnaC[Esche
richia coli] gi|118715|sp|P07905|DNAC#ECOLI (242ア
ミノ酸のうち48%一致)に類似 SEQ ID NO: 154： -0.016418, 68, 新規, gi|3025105|s
p|P76066|YDAW#ECOLI (155アミノ酸のうち54%一致)に類
似 SEQ ID NO: 155： -0.025506, 248, 新規 SEQ ID NO: 156： 0.022, 101, 新規, ハイポセティカ
ルタンパク質 例えばIroE[Salmonella enterica] gi|27
38251|gb|aaC46182.1| (249アミノ酸のうち29%一致)に
類似 SEQ ID NO: 157： -0.369811, 107, 新規 SEQ ID NO: 158： -0.00581, 569, 新規 SEQ ID NO: 159： -0.291558, 155, 推定 prophage mai
ntenanceタンパク質, Hok/Gef family 例えばMokW [Bac
teriophage 933W] gi|4585453|gb|aaD25481.1|AF125520
#76 (65アミノ酸のうち92%一致)に類似 SEQ ID NO: 160： -0.194196, 225, 新規, QD1 [Bacter
iophage N15] gi|2564084|gb|aaB81659.1| (64アミノ酸
のうち31%一致)に類似 SEQ ID NO: 161： -0.083415, 206, 新規 SEQ ID NO: 162： -0.462832, 114, 推定 crossover ju
nction endodeoxyribonuclease,に類似 Gp67 [Bacterio
phage HK97] gi|6901639|gb|aaF31142.1| (113アミノ酸
のうち60%一致); crossover junction endodeoxyribonu
clease Rus [Escherichia coli cryptic prophage DLP1
2] gi|2507117|sp|P40116|RUS#ECOLI (115アミノ酸のう
ち40%一致)に類似 SEQ ID NO: 163： 0.998039, 52, 推定 antiterminatio
n タンパク質, bacteriophage antitermination タンパ
ク質 例えばYbcQ [Escherichia coli cryptic prophage
DLP12 gi|4585416|gb|aaD25444.1|AF125520#39 (124ア
ミノ酸のうち77%一致)に類似 SEQ ID NO: 164： -0.436782, 88, 新規, [ハイポセテ
ィカル膜タンパク質] YpbD [Bacillus subtilis] gi|17
30886|sp|P50730|YPBD#BACSU (128アミノ酸のうち30%一
致)に類似 SEQ ID NO: 165： -0.286022, 94, 新規, ハイポセティ
カルタンパク質 [Bacteriophage P27] gi|8346569|emb|
CAB93762.1| (49アミノ酸のうち97%一致)に類似 SEQ ID NO: 166： 0.757522, 114, 推定 転写調節因子,
転写調節因子 例えばYhiW [Escherichia coli] gi|586
679|sp|P37638|YHIW#ECOLI (187アミノ酸のうち37%一
致)に類似 SEQ ID NO: 167： 0.175785, 224, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage 933W] gi|45854
19|gb|aaD25447.1|AF125520#42 (613アミノ酸のうち53%
一致)に類似 SEQ ID NO: 168： -0.464706, 52, transposase, ハイ
ポセティカルタンパク質[Escherichia coli プラスミド
pO157 insertion sequence IS629] gi|7444868|pir||T
00241 (116アミノ酸のうち100%一致)と同じ SEQ ID NO: 169： -0.152174, 254, 推定 transposase,
transposases 例えば[Escherichia coli プラスミド p
O157 insertion sequence IS629] gi|7443862|pir||T00
240 (220アミノ酸のうち98%一致)に類似 SEQ ID NO: 170： -0.400502, 200, 推定 転写調節因
子, PerC (BfpW) [Escherichia coli] gi|1172431|sp|P
43475|PERC#ECOLI (87アミノ酸のうち47%一致)に類似 SEQ ID NO: 171： -0.431915, 142, リポタンパク質 Rz
1 タンパク質前駆体, Rz1前駆体 例えば[Bacteriophage
933W] gi|4585425|gb|aaD25453.1|AF125520#48(61アミ
ノ酸のうち98%一致); [Bacteriophage lambda] gi|5407
38|pir||JN0750(61アミノ酸のうち70%一致) に類似 SEQ ID NO: 172： -0.121552, 117, endoペプチダーゼ
(host cell lysis), endoペプチダーゼ 例えば[Bacteri
ophage VT2-Sa] gi|5881639|dbj|Baa84330.1| (154アミ
ノ酸のうち88%一致)に類似 SEQ ID NO: 173： -0.561452, 538, 新規 SEQ ID NO: 174： -0.275207, 243, 新規 SEQ ID NO: 175： -0.345833, 121, host cell lysis,
endolysins 例えば[Bacteriophage H-19B] gi|4335686|
gb|aaD17382.1| (177アミノ酸のうち94%一致)に類似 SEQ ID NO: 176： -0.521101, 110, 新規SEQ ID NO: 17
7： -0.46, 156, 新規 SEQ ID NO: 178： -0.444527, 403, 新規 SEQ ID NO: 179： -0.033648, 319, holin タンパク質
(host cell lysis), holin タンパク質 例えば[Bacteri
ophage VT2-Sa] gi|5881636|dbj|Baa84327.1| (69アミ
ノ酸のうち91%一致)に類似 SEQ ID NO: 180： 0.066393, 245, 新規, GTGスタート SEQ ID NO: 181： -0.292064, 127, 新規, ハイポセテ
ィカルタンパク質 例えばL0013 [Escherichia coli O15
7:H7 strain EDL933] gi|3414881|gb|aaC31492.1|(133
アミノ酸のうち99%一致)に類似 SEQ ID NO: 182： -0.271985, 258, 新規, ハイポセテ
ィカルタンパク質 例えばL0014 [Escherichia coli O15
7:H7 strain EDL933] gi|3414882|gb|aaC31493.1|(115
アミノ酸のうち100%一致)と同じ SEQ ID NO: 183： -0.112369, 381, 新規, ハイポセテ
ィカルタンパク質 例えばL0015 [Escherichia coli O15
7:H7 strain EDL933] gi|3414883|gb|aaC31494.1|(の51
2アミノ酸うち100%一致)に類似 SEQ ID NO: 184： -0.165341, 353, 推定 terminase sm
all subunit,terminase small subunits 例えば[Bacter
iophage N15] gi|2507082|sp|P31061|NOHA#ECOLIのC-末
端部分(75アミノ酸のうち46%一致)に類似, GTGスター
ト, probably disrupted by IS insertion SEQ ID NO: 185： -0.206736, 194, terminase large s
ubunit, terminase large subunits 例えば[Bacterioph
age 21] gi|2851579|sp|P36693|TERL#BPP21 (637アミノ
酸のうち91%一致)に類似 SEQ ID NO: 186： -0.392375, 342, portal タンパク
質, portal タンパク質 例えばGP4 [Bacteriophage P2
1] gi|549295|sp|P36272|VG04#BPP21 (530アミノ酸のう
ち98%一致)に類似 SEQ ID NO: 187： -0.188742, 152, head-tail preconn
ectorタンパク質, head-tail preconnectorタンパク質
例えばGp5 [Bacteriophage P21] gi|549296|sp|P36273|
VG05#BPP21 (501アミノ酸のうち97%一致)に類似, GTGス
タート SEQ ID NO: 188： 0.734105, 347, head decoration タ
ンパク質, head decoration タンパク質 例えばGpshp
[Bacteriophage P21] gi|549437|sp|P36275|VSHP#BPP21
(115アミノ酸のうち95%一致)に類似 SEQ ID NO: 189： -0.317188, 193, possible major he
adタンパク質, major head タンパク質 例えばGp7 [Bac
teriophage P21] gi|547612|sp|P36270|HEAD#BPP21のN-
末端部分(88アミノ酸のうち95%一致)に類似 SEQ ID NO: 190： -0.249738, 192, 新規 SEQ ID NO: 191： 0.297015, 68, 推定 tail componen
t, minor tail タンパク質 例えばGpG [Bacteriophage
lambda] gi|138842|sp|P03734|VMTG#LAMBD (143アミノ
酸のうち68%一致)に類似 SEQ ID NO: 192： -0.083333, 103, 推定 minor tail c
omponent, minor tailタンパク質 GpG-T [Bacteriophag
e lambda] gi|7429179|pir||TLBPTL (124アミノ酸のう
ち72%一致)に類似, probably produced by translation
al frameshift SEQ ID NO: 193： 0, 75, tail length determinator,
tail length tape measure タンパク質 例えばGpH [Bac
teriophage lambda] gi|138843|sp|P03736|VMTH#LAMBD
(859アミノ酸のうち77%一致)に類似 SEQ ID NO: 194： -0.427011, 697, minor tail compon
ent, minor tail タンパク質 例えばGpM [Bacteriophag
e lambda] gi|138845|sp|P03737|VMTM#LAMBD (109アミ
ノ酸のうち82%一致)に類似 SEQ ID NO: 195： 0.565, 41, minor tail component,
minor tail タンパク質例えばGpL [Bacteriophage lamb
da] gi|138844|sp|P03738|VMTL#LAMBD (232アミノ酸の
うち76%一致)に類似 SEQ ID NO: 196： 0.101111, 91, tail assembly タン
パク質, tail assemblyタンパク質 例えばGpK [Bacteri
ophage lambda] gi|139638|sp|P03729|VTAK#LAMBD (196
アミノ酸のうち84%一致)に類似 SEQ ID NO: 197： -0.5, 51, tail assembly タンパク
質, tail assembly タンパク質 例えばGpI [Bacterioph
age lambda] gi|139637|sp|P03730|VTAI#LAMBD (224ア
ミノ酸のうち68%一致)に類似 SEQ ID NO: 198： -1.1875, 65, 新規 SEQ ID NO: 199： -0.140541, 75, copper/zinc supero
xide dismutase, copper/zinc-superoxide dismutases
例えば[Salmonella typhimurium] gi|2462699|emb|Caa7
3588.1| (175アミノ酸のうち58%一致)に類似 SEQ ID NO: 200： -0.113333, 91, 推定 host specific
ity タンパク質, host specificity タンパク質 例えば
GpJ [Bacteriophage lambda] gi|138412|sp|P03749|VHS
J#LAMBD (1156アミノ酸のうち65%一致)に類似 SEQ ID NO: 201： -0.59375, 65, 推定 外膜タンパク
質, Lom外膜タンパク質 例えば[prophage P-EibA] gi|7
532789|gb|aaF63231.1|AF151091#2 (199アミノ酸のうち
68%一致)に類似 SEQ ID NO: 202： 0.147917, 49, 推定 tail fiberタン
パク質, 推定 tail fiber タンパク質 例えば[Bacterio
phage 933W] gi|4585436|gb|aaD25464.1|AF125520#59
(370アミノ酸のうち38%一致)に類似 SEQ ID NO: 203： -0.707843, 103, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585437|g
b|aaD25465.1|AF125520#60 (129アミノ酸のうち93%一
致)に類似; 933W gi|4585436|gb|aaD25464.1|AF125520#
59の推定 tailタンパク質のC-末端部分 (89アミノ酸の
うち93%一致)に類似 SEQ ID NO: 204： 0.03369, 375, 新規, GTGスタート SEQ ID NO: 205： -0.295604, 92, 推定 secreted effe
ctorタンパク質, EspFタンパク質 例えば[Escherichia
coli strain E2348/69] gi|2865308|gb|aaC38400.1| (8
7アミノ酸のうち37%一致); L0016 - Escherichia coli
gi|3414884|gb|aaC31495.1| (126アミノ酸のうち38%一
致)に類似 SEQ ID NO: 206： -0.495808, 168, 新規, avirulence
タンパク質 A [Pseudomonas syringae] gi|114726|sp|P
11437|AVRA#PSESG (56アミノ酸のうち46%一致)に部分的
に類似 SEQ ID NO: 207： -0.350549, 92, 推定 インテグラー
ゼ, インテグラーゼ [Bacteriophage 933W] gi|4585378
|gb|aaD25406.1|AF125520#1と同じ, しかしスタートが
異なる; インテグラーゼ 例えば[Escherichia coli rac prophag
e] gi|6166234|sp|P76056|INTR#ECOLI (408アミノ酸の
うち42%一致)に類似 SEQ ID NO: 208： 0.199342, 153, 推定 excisionase,
推定 excisionase [Bacteriophage 933W] gi|4585379|g
b|aaD25407.1|AF125520#2と同じ SEQ ID NO: 209： 0.463492, 64, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|4585380|gb|
aaD25408.1|AF125520#3と同じ SEQ ID NO: 210： -0.033136, 170, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585381|g
b|aaD25409.1|AF125520#4と同じ, しかしスタートが異
なる SEQ ID NO: 211： -0.402415, 208, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585382|g
b|aaD25410.1|AF125520#5と同じ; ハイポセティカルタ
ンパク質 [Bacteriophage 933W] gi|4585455|gb|aaD254
83.1|AF125520#78 (80アミノ酸のうち50%一致)に類似 SEQ ID NO: 212： -0.577922, 78, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|4585383|gb|
aaD25411.1|AF125520#6 (95アミノ酸のうち100%一致)と
同じ SEQ ID NO: 213： 0.356338, 72, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|4585384|gb|
aaD25412.1|AF125520#7 (72アミノ酸のうち100%一致)と
同じ, GTGスタート SEQ ID NO: 214： -0.410847, 296, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585385|g
b|aaD25413.1|AF125520#8 (95アミノ酸のうち100%一致)
と同じ, GTGスタート SEQ ID NO: 215： -0.942593, 109, 新規,ハイポセティ
カルタンパク質 [Bacteriophage VT2-Sa] gi|5881600|d
bj|Baa84291.1| (155アミノ酸のうち100%一致)と同じ SEQ ID NO: 216： -0.260656, 245, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585386|g
b|aaD25414.1|AF125520#9 (257アミノ酸のうち100%一
致)と同じ;, ハイポセティカルタンパク質 例えば[Bact
eriophage 933W] gi|4585455|gb|aaD25483.1|AF125520#
78 (の157アミノ酸うち95%一致)に類似, GTGスタート SEQ ID NO: 217： -0.421638, 172, 新規, C4-type zin
c finger タンパク質 (TraR family) 例えばgi|4585456
|gb|aaD25484.1|AF125520#79 (73アミノ酸のうち79%一
致)に類似 SEQ ID NO: 218： -0.312093, 646, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] と同じ, しか
しスタートが異なる; orf61 [Bacteriophage lambda] g
i|508993|gb|aaA96566.1| (46アミノ酸のうち93%一致)
に類似 SEQ ID NO: 219： -0.186957, 47, 新規, ハイポセティ
カルタンパク質 [Bacteriophage VT2-Sa] gi|5881603|d
bj|Baa84294.1| (63アミノ酸のうち100%一致)と同じ; o
rf63 [Bacteriophage lambda] gi|508994|gb|aaA96567.
1| (61アミノ酸のうち90%一致)に類似 SEQ ID NO: 220： -0.418537, 411, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881604
|dbj|Baa84295.1|と同じ, しかしスタートが異なる; or
f60a [Bacteriophage lambda] gi|508995|gb|aaA96568.
1| (60アミノ酸のうち96%一致)に類似 SEQ ID NO: 221： -0.531132, 213, exonuclease, exon
uclease [Bacteriophagelambda] gi|2981722|pdb|1AVQ|
A (226アミノ酸のうち98%一致)に類似 SEQ ID NO: 222： -0.137079, 90, recombination タン
パク質 Bet, Bet [Bacteriophage VT2-Sa] gi|5881606|
dbj|Baa84297.1| (261アミノ酸のうち100%一致)と同じ;
Bet [Bacteriophage lambda] gi|137511|sp|P03698|VB
ET#LAMBD (261アミノ酸のうち99%一致)に類似 SEQ ID NO: 223： -0.533645, 215, host-nuclease inh
ibitorタンパク質 Gam,Gamタンパク質 例えば[Bacterio
phage lambda] gi|138128|sp|P03702|VGAM#LAMBD (138
アミノ酸のうち97%一致)に類似 SEQ ID NO: 224： -0.435294, 52, Kil タンパク質, ki
l [Bacteriophage VT2-Sa] gi|5881608|dbj|Baa84299.1
|と同じ; kill タンパク質 例えば[Bacteriophage lamb
da] gi|138622|sp|P03758|VKIL#LAMBD (89アミノ酸のう
ち98%一致)に類似 SEQ ID NO: 225： -0.714458, 167, 調節タンパク質cII
I (antitermination), cIII [Bacteriophage lambda] g
i|133366|sp|P03044|RPC3#LAMBD (54アミノ酸のうち100
%一致)と同じ SEQ ID NO: 226： 0.126027, 74, single strand結合タ
ンパク質 Ea10, Ea10 [Bacteriophage VT2-Sa] gi|5881
610|dbj|Baa84301.1| (122アミノ酸のうち100%一致)と
同じ; Ea10 [Bacteriophage lambda] gi|137630|sp|P03
757|VE10#LAMBD (122アミノ酸のうち99%一致)に類似 SEQ ID NO: 227： -0.575177, 142, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881612
|dbj|Baa84303.1| (83アミノ酸のうち100%一致)と同じ SEQ ID NO: 228： -1.413333, 61, 推定 anti-terminat
ion Nタンパク質, Nタンパク質 [Bacteriophage VT2-S
a] gi|5881613|dbj|Baa84304.1|と同じ, しかしスター
トが異なる; Nタンパク質 例えば[Bacteriophage 933W]
gi|4585397|gb|aaD25425.1|AF125520#20 (90アミノ酸
のうち42%一致)に類似 SEQ ID NO: 229： -0.125172, 291, 新規 SEQ ID NO: 230： -0.297787, 950, 新規 SEQ ID NO: 231： -0.469647, 795, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881614
|dbj|Baa84305.1| (173アミノ酸のうち100%一致)と同じ SEQ ID NO: 232： -0.370764, 302, 推定 cI リプレッ
サータンパク質, cI [Bacteriophage lambda] gi|13335
3|sp|P03034|RPC1#LAMBD (208アミノ酸のうち70%一致)
に類似 SEQ ID NO: 233： 0.007584, 357, 推定 調節タンパク
質, ハイポセティカルタンパク質 [Bacteriophage VT2-
Sa] gi|5881616|dbj|Baa84307.1|と同じ; c2 [Bacterio
phage L] gi|1469215|emb|Caa63999.1| (49アミノ酸の
うち42%一致)に類似 SEQ ID NO: 234： 0.418519, 55, 調節 タンパク質 CI
I, CII タンパク質 [Bacteriophage VT2-Sa] gi|588161
7|dbj|Baa84308.1| (98アミノ酸のうち100%一致)と同
じ; CII タンパク質 例えば[Enterobacteria phage HK0
22] gi|631957|pir||S42398 (98アミノ酸のうち96%一
致)に類似 SEQ ID NO: 235： -0.554044, 273, 新規, ハイポセテ
ィカルタンパク質 [Enterobacteria phage HK022] gi|6
32160|pir||S42399 (48アミノ酸のうち100%一致)と同
じ; orf48 [Bacteriophage P22] gi|871503|emb|Caa酸5
5155.1| (48アミノ酸のうち85%一致)に類似 SEQ ID NO: 236： -0.290062, 162, endoペプチダーゼ
(host cell lysis), endoペプチダーゼ 例えば[Bacteri
ophage lambda] gi|119368|sp|P00726|ENPP#LAMBD (153
アミノ酸のうち97%一致)に類似 SEQ ID NO: 237： -0.084177, 159, リポタンパク質 Rz
1前駆体, Rs1前駆体 例えば[Bacteriophage lambda] gi
|540738|pir||JN0750 (60アミノ酸のうち96%一致)に類
似 SEQ ID NO: 238： -0.384931, 74, 新規, Borタンパク
質前駆体 例えば[Bacteriophage lambda] gi|137520|sp
|P26814|VBOR#LAMBD (97アミノ酸のうち98%一致)に類似 SEQ ID NO: 239： -0.322581, 125, 新規, ハイポセテ
ィカルタンパク質 例えばYbcV [Escherichia coli] gi|
2495556|sp|P77598|YBCV#ECOLI (150アミノ酸のうち98%
一致)に類似 SEQ ID NO: 240： -0.276613, 125, 新規, YbcW [Esche
richia coli] gi|2495557|sp|P75720|YBCW#ECOLIと同じ SEQ ID NO: 241： 0.049693, 164, 新規, ハイポセティ
カルタンパク質 例えば[Escherichia coli] gi|1778472
|gb|aaB40755.1| (64アミノ酸のうち98%一致)に類似 SEQ ID NO: 242： -0.307692, 66, terminase small su
bunit, terminase smallsubunits 例えばNu1 [Bacterio
phage lambda] gi|139026|sp|P03707|TERS#LAMBD (181
アミノ酸のうち97%一致)に類似 SEQ ID NO: 243： -0.415, 281, 推定 terminase large
subunit, terminase large subunits 例えばタンパク
質 A [Bacteriophage lambda] gi|137616|sp|P03708|TE
RL#LAMBD (641アミノ酸のうち99%一致)に類似, GTGスタ
ート SEQ ID NO: - ： 0.61519, 80, head-to-tail joining
タンパク質, head-to-tail joining タンパク質 例え
ばGpW [Bacteriophage lambda] gi|138415|sp|P03727|V
HTJ#LAMBD (68アミノ酸のうち98%一致)に類似 SEQ ID NO: 485： -0.691397, 373, 推定 portalタンパ
ク質 portalタンパク質例えばGpB [Bacteriophage lamb
da] gi|138762|sp|P03710|VMCB#LAMBD (533アミノ酸の
うち98%一致)に類似 SEQ ID NO: 486： -0.496629, 90, minor capsidタンパ
ク質, minor capsid タンパク質 例えばタンパク質 C
[Bacteriophage lambda] gi|137565|sp|P03711|VCAC#LA
MBD (439アミノ酸のうち97%一致)に類似, GTGスタート,
Nu3-homologを含む SEQ ID NO: 487： -0.65931, 146, major capsid タン
パク質, major capsid タンパク質 例えばGpD [Bacteri
ophage lambda] gi|137566|sp|P03712|VCAD#LAMBD(110
アミノ酸のうち99%一致)に類似 SEQ ID NO: 488： 0.03027, 186, 推定 major capsid
タンパク質, major capsidタンパク質 例えばGpE [Bact
eriophage lambda] gi|116752|sp|P03713|HEAD#LAMBD
(341アミノ酸のうち98%一致)に類似 SEQ ID NO: 489： -0.356579, 77, DNA packaging タン
パク質, DNA packagingタンパク質 例えばGpFI [Bacter
iophage lambda] gi|139324|sp|P03709|VPF1#LAMBD (13
2アミノ酸のうち98%一致)に類似 SEQ ID NO: 490： -0.53038, 159, minor capsidタンパ
ク質, minor capsidタンパク質 例えばGpFII [Bacterio
phage lambda] gi|137575|sp|P03714|VCF2#LAMBD(117ア
ミノ酸のうち94%一致)に類似, GTGスタート SEQ ID NO: 491： -0.797196, 108, minor tail タンパ
ク質, minor tail タンパク質 例えばGpZ [Bacteriopha
ge lambda] gi|138849|sp|P03731|VMTZ#LAMBD (192アミ
ノ酸のうち98%一致)に類似 SEQ ID NO: 492： -0.397163, 142, minor tailタンパ
ク質, minor tailタンパク質 例えばGpU [Bacteriophag
e lambda] gi|138847|sp|P03732|VMTU#LAMBD (131アミ
ノ酸のうち100%一致)に類似 SEQ ID NO: 493： -0.69942, 346, major tail タンパ
ク質 V, major tail タンパク質 例えばGpV [Bacteriop
hage lambda] gi|138848|sp|P03733|VMTV#LAMBD (246ア
ミノ酸のうち95%一致)に類似 SEQ ID NO: 494： -0.687309, 198, minor tail タンパ
ク質, minor tail タンパク質 例えばGpG [Bacteriopha
ge lambda] gi|138842|sp|P03734|VMTG#LAMBD (140アミ
ノ酸のうち96%一致)に類似 SEQ ID NO: 495： -0.404622, 239, 推定 minor tail
タンパク質, minor tailタンパク質 例えばGpT [Bacter
iophage lambda] gi|138846|sp|P03735|VMTT#LAMBD (14
4アミノ酸のうち99%一致)に類似, probably produced b
y translationalframeshift SEQ ID NO: 496： -0.494286, 106, tail length tape
measure タンパク質前駆体, tail length tape measure
タンパク質前駆体 例えばGpH [Bacteriophage lambda]
gi|138843|sp|P03736|VMTH#LAMBD (849アミノ酸のうち
96%一致)に類似 SEQ ID NO: 497： -0.175, 101, minor tail タンパク
質, minor tail タンパク質 例えばGpM [Bacteriophage
lambda] gi|138845|sp|P03737|VMTM#LAMBD (109アミノ
酸のうち94%一致)に類似 SEQ ID NO: 498： -0.355238, 106, minor tail タンパ
ク質, minor tail タンパク質 例えばGpL [Bacteriopha
ge lambda] gi|138844|sp|P03738|VMTL#LAMBD (232アミ
ノ酸のうち98%一致)に類似 SEQ ID NO: 499： -0.282857, 106, tail assembly タ
ンパク質, tail assemblyタンパク質 例えばGpK [Bacte
riophage lambda] gi|139638|sp|P03729|VTAK#LAMBD (1
99アミノ酸のうち97%一致)に類似 SEQ ID NO: 500： -0.675172, 146, tail assemblyタン
パク質, tail assemblyタンパク質 例えばGpI [Bacteri
ophage lambda] gi|139637|sp|P03730|VTAI#LAMBD (223
アミノ酸のうち98%一致)に類似 SEQ ID NO: 501： 0.114286, 64, host specificityタ
ンパク質, host specificityタンパク質 例えばGpJ [Ba
cteriophage lambda] gi|138412|sp|P03749|VHSJ#LAMBD
(1131アミノ酸のうち89%一致)に類似 SEQ ID NO: 502： -0.550256, 196, 推定 膜タンパク質
前駆体, 膜タンパク質 Lom前駆体 例えば[prophage P-E
ibA gi|7532789|gb|aaF63231.1|AF151091#2 (199アミノ
酸のうち69%一致); [Bacteriophage lambda] gi|138693
|sp|P03701|VLOM#LAMBD (199アミノ酸のうち44%一致)に
類似 SEQ ID NO: 503： 0.15098, 52, 推定 tail fiber タン
パク質, 推定 tail fiber タンパク質 例えばGp37 [Esc
herichia coli] gi|7466858|pir||G64887 (496アミノ酸
のうち95%一致)に類似 SEQ ID NO: 504： 0.198571, 71, tail fiber assembly
タンパク質, tail fiber assemblyタンパク質 例えばO
rf194 [Bacteriophage lambda] gi|139990|sp|P03740|Y
194#LAMBD (191アミノ酸のうち92%一致)に類似 SEQ ID NO: 505： -0.96087, 93, 新規, ハイポセティ
カルタンパク質 例えば推定 catalase [Salmonella typ
himurium] gi|7162108|emb|CAB76676.1| (289アミノ酸
のうち84%一致)に類似 SEQ ID NO: 506： -0.407736, 350, 新規, ハイポセテ
ィカルタンパク質 例えばYciE [Escherichia coli] gi|
775201|gb|aaA65179.1| (168アミノ酸のうち88%一致)に
類似 SEQ ID NO: 507： -0.273387, 125, 新規, ハイポセテ
ィカルタンパク質 例えばYciF [Escherichia coli] gi|
140432|sp|P21362|YCIF#ECOLI (166アミノ酸のうち80%
一致)に類似 SEQ ID NO: 508： -0.473626, 274, 新規, ハイポセテ
ィカルタンパク質 例えばYciG-homolog [Salmonella ty
phimurium] gi|6851081|emb|CAB71036.1| (60アミノ酸
のうち88%一致)に類似, (YciG, E. coli [in TONB-TRPA
INTERGENIC REGION] にも類似) SEQ ID NO: 509： 0.544262, 62, 新規, ハイポセティ
カルタンパク質 例えばybcY [Escherichia coli] gi|24
95559|sp|P77460|YBCY#ECOLI (143アミノ酸のうち99%一
致)に類似 SEQ ID NO: 510： -0.353615, 167, 新規, ハイポセテ
ィカルタンパク質 例えばYlcE [Escherichia coli] gi|
3025212|sp|P77087|YLCE#ECOLI (61アミノ酸のうち98%
一致)に類似, (orf194, lambda, phage tail assembly
タンパク質に類似) SEQ ID NO: 511： -0.336744, 646, 新規, ハイポセテ
ィカルタンパク質 例えばL0013 [Escherichia coli O15
7:H7 EDL933] gi|3414881|gb|aaC31492.1| (133アミノ
酸のうち99%一致)に類似 SEQ ID NO: 512： 0.348333, 61, 新規, ハイポセティ
カルタンパク質 例えばL0014 [Escherichia coli O157:
H7 EDL933] gi|3414882|gbaaC31493.1| (115アミノ酸の
うち100%一致)に類似 SEQ ID NO: 513： -0.398876, 90, 新規, ハイポセティ
カルタンパク質 例えばL0015 [Escherichia coli O157:
H7 EDL933] gi|3414883|gb|aaC31494.1| (512アミノ酸
のうち100%一致) に類似 SEQ ID NO: 514： 0.087324, 72, 推定 fimbrialタンパ
ク質 (partial), truncated BfpA [Escherichia coli]
gi|4808944|gb|aaD30026.1|AF119170#1 (40アミノ酸の
うち75%一致)に類似 SEQ ID NO: 515： -0.027193, 115, 新規, ハイポセテ
ィカルタンパク質 例えば[プラスミド F] gi|8918853|d
bj|Baa97900.1| (492アミノ酸のうち76%一致)に類似 SEQ ID NO: 516： -0.440678, 178, 外膜 プロテアーゼ
前駆体, 外膜 プロテアーゼ前駆体 例えばプロテアーゼ
VII前駆体 [Escherichia coli] gi|129161|sp|P09169|
OMPT#ECOLI (317アミノ酸のうち98%一致)に類似 SEQ ID NO: 517： -0.283069, 190, 新規, ハイポセテ
ィカルタンパク質 例えば推定 DNA結合 タンパク質 [St
reptomyces coelicolor A3(2)] gi|6855358|emb|CAB712
49.1| (171アミノ酸のうち34%一致)に類似 SEQ ID NO: 518： -0.234839, 156, transposase, ハイ
ポセティカルタンパク質[Escherichia coli プラスミド
pO157 insertion sequence IS629] gi|7444868|pir||T
00241と同じ SEQ ID NO: 519： 0.076471, 69, transposase, transp
osase [Escherichia coli プラスミド pO157 insertion
sequence IS629] gi|7443862|pir||T00240と同じ SEQ ID NO: 520： 0.045946, 75, ハイポセティカルタ
ンパク質 例えばYPJA#ECOLI gi|2507221|sp|P52143の部
分(1336-1569 / 1569アミノ酸) (234アミノ酸のうち96%
一致)に類似, GTGスタート SEQ ID NO: 521： -0.288889, 73, 新規 SEQ ID NO: 522： 1.11087, 47, transposase (inserti
on sequence IS629), gi|7443862|pir|T00240 (296アミ
ノ酸のうち96%一致)に類似 SEQ ID NO: 523： -0.714754, 62, transposase (inser
tion sequence IS629),ハイポセティカルタンパク質.
例えば[Shigella flexneri SHI-2 pathogenicityislan
d] gi|5532454|gb|aaD44738.1|AF141323#9 (108アミノ
酸のうち98%一致)に類似 SEQ ID NO: 524： -0.468595, 122, 推定 TonB 依存性
外膜 レセプター, TonB依存性 外膜 レセプター PrrA
[Escherichia coli CFT073] gi|3661477|gb|aaC61709.1
| (656アミノ酸のうち97%一致)に類似 525： -0.648128, 188, molybdenum 輸送タンパク質,mo
lybdenum 輸送 タンパク質 例えばgi|3661478|gb|aaC61
710.1| (284アミノ酸のうち91%一致)に類似 SEQ ID NO: 526： -0.117179, 554, 新規 SEQ ID NO: 527： -0.148992, 646, 新規, ハイポセテ
ィカルタンパク質 例えばOrf2 [Escherichia coli CFT0
73] gi|3661479|gb|aaC61711.1| (214アミノ酸のうち98
%一致)に類似 SEQ ID NO: 528： -0.435414, 834, 推定 ferric enter
obactin輸送, ferric enterobactin輸送 ATP-結合タン
パク質 [Escherichia coli CFT073] gi|3661480|gb|aaC
61712.1| (148アミノ酸のうち79%一致)に類似 SEQ ID NO: 529： -0.008333, 109, 推定 ABCトランス
ポーター タンパク質 (permease), ABCトランスポータ
ー permeases 例えば[Haemophilus influenzae] gi|250
1391|sp|Q57130|YE71#HAEIN (323アミノ酸のうち40%一
致)に類似 SEQ ID NO: 530： -0.180172, 117, 推定 ABC トランス
ポーター, iron (iii) ABC トランスポーター, ATP-結
合 タンパク質 [Pyrococcus abyssi (strain Orsay)] g
i|7519847|pir||A75077 (246アミノ酸のうち24%一致);
ハイポセティカルタンパク質 例えば[Methanosarcina b
arker] gi|2129363|pir||S62196 (259アミノ酸のうち26
%一致)に類似 SEQ ID NO: 531： -0.46554, 149, 新規 SEQ ID NO: 532： 0.172807, 115, 推定 インテグラー
ゼ, phage インテグラーゼ family, 例えば[Bacterioph
age 21] gi|138558|sp|P27077|VINT#BPP21 (370アミノ
酸のうち50%一致)に類似 SEQ ID NO: 533： -0.333614, 239, 推定 excisionase,
excisionases 例えば[Bacteriophage 21] gi|139674|s
p|P27079|VXIS#BPP21 (77アミノ酸のうち45%一致)に類
似 SEQ ID NO: 534： -0.296774, 125, 推定 exonuclease,
N-末端部分 (1-256アミノ酸)が ハイポセティカルタン
パク質 例えばydfE [Escherichia coli crypticprophag
e/truncated insertion sequence IS2 fusion] gi|7859
7|pir||S03698 (256アミノ酸のうち92%一致)に類似; Ce
ntral part (209-622アミノ酸)がExodeoxyribonuclease
VIII (EC 3.1.11.-) (Exo VIII). [Escherichia coli]
gi|1742216|dbj|Baa14950.1| (361アミノ酸のうち39%
一致)に類似; C-末端部分 (644-776アミノ酸)が exonuc
lease [phage T4] gi|119690|sp|P04536|EXOD#BPT4 (13
3アミノ酸のうち27%一致)に類似 SEQ ID NO: 535： -0.091398, 94, 新規, ハイポセティ
カルタンパク質 YdfD [Escherichia coli] gi|140587|s
p|P29010|YDFD#ECOLI (63アミノ酸のうち96%一致)に類
似 SEQ ID NO: 536： -0.238298, 142, 推定 cell divisio
n inhibition タンパク質, cell division inhibitor d
icB [Escherichia coli] gi|2507009|sp|P09557|DICB#E
COLI (62アミノ酸のうち93%一致)に類似 SEQ ID NO: 537： -0.317647, 953, 新規 SEQ ID NO: 538： -0.665487, 114, 新規 SEQ ID NO: 539： -0.364655, 233, 新規, ハイポセテ
ィカル8.3 KD タンパク質YdfC [Escherichia coli] gi|
140586|sp|P21418|YDFC#ECOLI, (72アミノ酸のうち94%
一致)に類似 SEQ ID NO: 540： -0.672619, 85, division inhibitio
n gene dicBの推定 リプレッサー タンパク質, DicA リ
プレッサー タンパク質 of division inhibitiongene d
icB [Escherichia coli] gi|118631|sp|P06966|DICA#EC
OLI (131アミノ酸のうち63%一致)に類似; N-末端部分(1
-68アミノ酸)が タンパク質 [Bacteriophage P22] gi|1
33359|sp|P03035|RPC2#BPP22のN-末端部分(68アミノ酸
のうち61%一致)に類似 SEQ ID NO: 541： -0.47226, 293, division inhibitio
n gene dicBの推定 リプレッサー タンパク質, DicC リ
プレッサー タンパク質 of division inhibitiongene d
icB [Escherichia coli] gi|118633|sp|P06965|DICC#EC
OLI (74アミノ酸のうち82%一致) に類似; N-末端部分
(1-57アミノ酸)が Cro [Bacteriophage P22] gi|132195
|sp|P09964|RCRO#BPP22 (57アミノ酸の36うち%一致)に
類似(低い) SEQ ID NO: 542： -0.389388, 246, 新規, ハイポセテ
ィカル11.0 kDa タンパク質 YdfX [Escherichia coli]
gi|3183265|sp|P76165|YDFX#ECOLI (93アミノ酸のうち8
7%一致) に類似 SEQ ID NO: 543： -0.211702, 95, 新規, 複製 termina
tion factor (prepriming タンパク質 I) DnaT [Escher
ichia coli] gi|1361001|pir||S56589 (83アミノ酸の51
うち%一致)に類似 SEQ ID NO: 544： -0.145524, 783, 推定 ファージ複製
タンパク質, ファージ複製 タンパク質 例えばタンパ
ク質 14 [phage phi-80] gi|137937|sp|P14814|VG14#BP
PH8 (129アミノ酸のうち48%%一致) に類似 SEQ ID NO: 545： -0.473433, 1134, 推定 fimbrial mi
nor pilin タンパク質前駆体, fimbrial minor pilin
タンパク質前駆体 例えばPap-related pilus H [Escher
ichia coli] gi|837337|gb|aaA67692.1|のN-末端部分(5
6アミノ酸のうち75%類似) に類似, GTGスタート, proba
bly interrupted by frameshift SEQ ID NO: 546： 0.168627, 52, fimbrial minor pili
n タンパク質前駆体 (partial), fimbrial minor pilin
タンパク質前駆体, 例えばPrsH [Escherichia coli] g
i|1172646|sp|P42185|PRSH#ECOLIのC-末端部分 (50アミ
ノ酸のうち62%一致) に類似 SEQ ID NO: 547： 0.350336, 150, 推定 colonization
factor, Anm (attachment and effacement of negative
mutant) タンパク質 [Escherichia coli] gi|6715555|
gb|aaB48445.2| (252アミノ酸のうち100%一致)と同じ;
accessory colonization factor AcfC [Vibrio cholera
e] gi|558481|gb|aaA50604.1| (239アミノ酸のうち50%
一致) に類似 SEQ ID NO: 548： -0.544186, 302, 推定 toxic タンパ
ク質 (prophage maintenance; modulation host cell k
illing), Hok/Gef family 例えばGef [Escherichia col
i] gi|2120017|pir||S40540 (69アミノ酸のうち79%一
致) に類似 SEQ ID NO: 549： -0.409434, 54, 新規, Rem タンパク
質 [Escherichia coli]gi|132324|sp|P07010|REM#ECOLI
(84アミノ酸のうち71%一致) に類似 SEQ ID NO: 550： -0.517544, 58, 新規, orf QD1 [Ba
cteriophage N15] gi|2564084|gb|aaB81659.1| (64アミ
ノ酸のうち33%一致)に類似(低い) SEQ ID NO: 551： -0.641758, 92, 新規, ハイポセティ
カルタンパク質 b1560 [Escherichia coli] gi|7466196
|pir||C64911 (347アミノ酸のうち86%一致); に類似 ハ
イポセティカルタンパク質 A [phage P1] gi|732234|sp
|Q06262|YORA#BPP1 (347アミノ酸のうち85%一致) に類
似, GTGスタート SEQ ID NO: 552： -0.407064, 454, 推定 crossover ju
nction endodeoxyribonuclease, Gp67 [Bacteriophage
HK97] gi|6901639|gb|aaF31142.1| (113アミノ酸のうち
60%一致); crossover junction endodeoxyribonuclease
s 例えばRus [Escherichia coli cryptic lambdoid pro
phage DLP12] gi|2507117|sp|P40116|RUS#ECOLI (115ア
ミノ酸のうち39%一致)に類似 SEQ ID NO: 553： -0.475714, 71, 新規 SEQ ID NO: 1213： -0.410758, 410, 新規 [ハイポセテ
ィカルリポタンパク質],C-末端部分が orf2 [Bacteriop
hage P27] gi|8346569|emb|CAB93762.1| (63アミノ酸の
うち98%一致)に類似, GTGスタート SEQ ID NO: 1214： -0.622581, 63, 推定 DNA methylas
e, orf3 [BacteriophageP27] gi|8346570|emb|CAB9376
3.1| (312アミノ酸のうち85%一致)に類似; adenine spe
cific modification methylases 例えばGp52 [phage N1
5] gi|7433503|pir||T13139 (270アミノ酸のうち55%一
致) に類似 SEQ ID NO: 1215： -0.359514, 248, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage 933W] gi|458
5419|gb|aaD25447.1|AF125520#42 (613アミノ酸のうち5
2%一致) に類似 SEQ ID NO: 1216： 0.293846, 66, 推定 holinタンパク
質, holin タンパク質例えば[Bacteriophage 933W] gi|
4499808|emb|CAB39307.1| (71アミノ酸のうち95%一致)
に類似 SEQ ID NO: 1217： 0.377049, 62, 新規, ハイポセティ
カルタンパク質 YdfR [Escherichia coli] gi|3183262|
sp|P76160|YDFR#ECOLI (74アミノ酸のうち45%一致)に類
似 SEQ ID NO: 1218： -0.180952, 64, 推定 endolysin, e
ndolysins 例えば[Bacteriophage 933W] gi|4585422|gb
|aaD25450.1|AF125520#45 (177アミノ酸のうち96%一致)
に類似 SEQ ID NO: 1219： -0.23625, 81, 推定 antiリプレッ
サータンパク質, 推定 antiリプレッサー タンパク質 A
nt [Bacteriophage 933W] gi|4585423|gb|aaD25451.1|A
F125520と同じ; antiリプレッサー タンパク質 Ant [Ba
cteriophage P22]gi|131843|sp|P03037|RANT#BPP22 (12
6アミノ酸のうち49%一致)に類似 SEQ ID NO: 1220 -0.936364, 100, endoペプチダーゼ
(host lysis), Rz [Bacteriophage VT2-Sa] gi|5881639
|dbj|Baa84330.1|と同じ; Rz endoペプチダーゼ例えば
[Bacteriophage lambda] gi|119368|sp|P00726|ENPP#LA
MBD (153アミノ酸のうち69%一致) に類似 SEQ ID NO: 1221： -0.548598, 322, リポタンパク質 R
z1前駆体, Rz1 タンパク質前駆体 例えば[Bacteriophag
e 933W] gi|4585425|gb|aaD25453.1|AF125520#48(61ア
ミノ酸のうち98%一致); [Bacteriophage lambda] gi|54
0738|pir||JN0750(61アミノ酸のうち70%一致)に類似 SEQ ID NO: 1222： -0.179452, 74, 新規, ハイポセテ
ィカルタンパク質 例えば[Escherichia coli] gi|17784
72|gb|aaB40755.1| (67アミノ酸のうち70%一致)に類似 SEQ ID NO: 1223： -0.636194, 269, 推定 DNase, 推定
DNAse [Bacteriophagephi-C31] gi|1107475|emb|Caa62
587.1| (85アミノ酸のうち28%一致)に類似(低い) SEQ ID NO: 1224： 0.322807, 115, 新規 SEQ ID NO: 1225： -0.454217, 84, 推定 terminase sm
all subunit, 推定 terminase small subunit [Bacillu
s subtilis PBSX phage] gi|1722886|sp|P39785|XTMA#B
ACSU (57アミノ酸のうち42%一致)に類似(低い), GTGス
タート SEQ ID NO: 1226： -0.484559, 137, 推定 terminase l
arge subunit, phage D3terminase-様 タンパク質 [Hae
mophilus influenzae] gi|6739656|gb|aaF27357.1|AF19
8256#11 (472アミノ酸のうち22%一致) に類似 SEQ ID NO: 1227： -0.942222, 91, 推定 headタンパク
質/prohead プロテアーゼ, N-末端部分が推定 prohead
プロテアーゼ 例えば[Bacteriophage HK97] gi|1722780
|sp|P49860|VP4#BPHK7 (136アミノ酸のうち28%一致) に
類似; C-末端部分がmajor head タンパク質 [mycobacte
rium phage L5] gi|465114|sp|Q05223|VG17#BPML5 (280
アミノ酸のうち23%一致) に類似, GTGスタート SEQ ID NO: 1228： -0.382433, 75, 新規 SEQ ID NO: 1229： -0.597662, 386, 推定 portal タン
パク質, N-末端半分がhead portal タンパク質, 例えば
[Bacteriophage HK022] gi|6863114|gb|aaF30355.1|AF0
69308#3 (351アミノ酸のうち26%一致) に類似; C-末端
半分が推定 transducer タンパク質 [H. salinarum] gi
|3913878|sp|Q48317|HTR4#HALSAのC-末端半分(347アミ
ノ酸のうち21%一致)に類似 SEQ ID NO: 1230： -0.524865, 186, 新規 SEQ ID NO: 1231： -0.486352, 404, 推定 head-tail a
daptor, 推定 head-tailadaptors 例えば[Bacteriophag
e HK97] gi|6901597|gb|aaF31100.1| (111アミノ酸のう
ち45%一致) に類似 SEQ ID NO: 1232： -0.194643, 113, 新規, phage ハイ
ポセティカルタンパク質例えばGp10 [Bacteriophage HK
97] gi|6901598|gb|aaF31101.1| (148アミノ酸のうち75
%一致) に類似 SEQ ID NO: 1233： 0.009184, 99, 新規, Gp11 [Bacter
iophage HK97] gi|6901599|gb|aaF31102.1| (113アミノ
酸のうち49%一致) に類似 SEQ ID NO: 1234： -1.106849, 147, 推定 major tail
subunit, major tail subunit [Bacteriophage HK97] g
i|6901588|gb|aaF31091.1|AF069529#4 (234アミノ酸の
うち65%一致) に類似, GTGスタート SEQ ID NO: 1235： -1.563158, 58, 推定 tail assembl
y chaperone, 推定 tailassembly chaperon例えばp14
[Bacteriophage HK97] gi|6901600|gb|aaF31103.1| (12
4アミノ酸のうち62%一致) に類似 SEQ ID NO: 1236： -0.692373, 119, 新規, Gp14 [Bact
eriophage HK97] gi|6901601|gb|aaF31104.1|のC-末端
部分(94アミノ酸のうち60%一致)に類似, probablyprodu
ced by translational frameshift SEQ ID NO: 1237： -0.32604, 554, 推定 tail length
tape measure タンパク質,tail length tape measure
タンパク質 例えば[Bacteriophage HK97] gi|6901589|g
b|aaF31092.1|AF069529#5 (1022アミノ酸のうち52%一
致) に類似 SEQ ID NO: 1238： -0.727957, 94, 推定 minor tailタ
ンパク質, minor tailタンパク質 例えばGpM [Bacterio
phage lambda] gi|138845|sp|P03737|VMTM#LAMBD (110
アミノ酸のうち44%一致) に類似, GTGスタート SEQ ID NO: 1239： -0.284615, 92, 推定 minor tailタ
ンパク質, minor tailタンパク質 例えばGpL [Bacterio
phage lambda] gi|138844|sp|P03738|VMTL#LAMBD (137
アミノ酸のうち72%一致) に類似 SEQ ID NO: 631： -0.709473, 381, 推定 host specifi
cityタンパク質, host specificity タンパク質 例えば
GpJ [Bacteriophage lambda] gi|138412|sp|P03749|VHS
J#LAMBD (1157アミノ酸のうち69%一致) に類似 SEQ ID NO: 632： -0.351282, 79, 推定 外膜タンパク
質前駆体, 外膜タンパク質 Lom前駆体 例えば[prophage
P-EibA] gi|7532789|gb|aaF63231.1|AF151091#2(199ア
ミノ酸のうち77%一致); [Bacteriophage lambda] gi|13
8693|sp|P03701|VLOM#LAMBD (199アミノ酸のうち40%一
致) に類似 SEQ ID NO: 633： -0.545985, 275, 推定 tail fiber
タンパク質, tail fiberタンパク質 例えば[Bacterioph
age 933W] gi|4585436|gb|aaD25464.1|AF125520#59 (37
0アミノ酸のうち38%一致) に類似 SEQ ID NO: 634： -0.471244, 234, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585437|g
b|aaD25465.1|AF125520#60 (89アミノ酸のうち92%一致)
に類似 SEQ ID NO: 635： -0.194, 101, 新規 SEQ ID NO: 636： 1.042727, 111, 新規, ハイポセティ
カルタンパク質 例えばOrf2 [Escherichia coli strain
B171-8] gi|4126792|dbj|Baa36750.1| (111アミノ酸の
うち37%一致) に類似 SEQ ID NO: 637： -0.138976, 509, 新規 SEQ ID NO: 638： -0.319205, 152, インテグラーゼ,
インテグラーゼ 例えば[Bacteriophage HK022] gi|1385
60|sp|P16407|VINT#BPHK0, (229アミノ酸のうち89%一
致) に類似, N-末端の100アミノ酸が恐らく欠失 SEQ ID NO: 639： -0.625, 57, 新規 SEQ ID NO: 640： -0.083333, 97, 新規 SEQ ID NO: 641： -0.538333, 121, disrupted transpo
sase, 推定 transposases 例えば[Yersinia pestis プ
ラスミド pMT1] gi|2996347|gb|aaC13227.1|のC-末端部
分(89アミノ酸,のうち74%一致)に類似, TTGスタート SEQ ID NO: 642： -0.450655, 230, disrupted transpo
sase, の推定 transposases 例えば[Yersinia pestis
プラスミド pMT1] gi|7447905|pir||T14710 C-末端部分
(90アミノ酸のうち70%一致)に類似, N-末端部分(~180
アミノ酸)が欠失 SEQ ID NO: 643： 0.76381, 106, 新規, L0015 [Escher
ichia coli O157:H7 strain EDL933] gi|3414883|gb|aa
C31494.1|と同じ SEQ ID NO: 644： -0.675317, 159, 新規, L0014 [Esch
erichia coli O157:H7 strain EDL933] gi|3288157|emb
|Caa11510.1|と同じ SEQ ID NO: 645： -0.396079, 154, 新規, L0013 [Esch
erichia coli O157:H7 strain EDL933] gi|3414881|gb|
aaC31492.1|と同じ SEQ ID NO: 646： 0.016667, 61, 新規 SEQ ID NO: 647： 0.228866, 98, 新規, ハイポセティ
カルタンパク質 [insertion sequence IS630] gi|14094
3|spP16943|YIS5#SHISO (25アミノ酸のうち47%一致)に
類似(低い), TTGスタート SEQ ID NO: 648： -0.455333, 151, 新規 SEQ ID NO: 649： -0.113235, 69, 新規, ハイポセティ
カルタンパク質 例えばorf2 [Escherichia coli strain
B171-8] gi|4126790|dbj|Baa36748.1|, (206アミノ酸
のうち63%一致) に類似 SEQ ID NO: 650： -1.015625, 65, bfpT-regulated cha
perone-様タンパク質, TrcA (bfpT-r例えばulated chap
erone-様 タンパク質)-様タンパク質 例えばTrcA[Esche
richia coli strain B171-8] gi|4126789|dbj|Baa3674
7.1|, (195アミノ酸のうち72%一致) に類似 SEQ ID NO: 651： -0.513812, 182, 新規, ハイポセテ
ィカルタンパク質 [insertion sequence IS630] gi|140
943|spP16943|YIS5#SHISO (60アミノ酸のうち81%一致)
に部分的に類似, GTGスタート, probably disrupted SEQ ID NO: 652： -0.585648, 642, 新規, ハイポセテ
ィカル39 kDaタンパク質[insertion element IS630] gi
|1143207|gb|aaA84873.1|のN-末端部分 (54アミノ酸の
うち82%一致) に類似 SEQ ID NO: 653： -0.526471, 69, 新規, ハイポセティ
カルタンパク質 ORF2 [Escherichia coli strain B171-
8] gi|4126790|dbj|Baa36748.1| (167アミノ酸のうち38
%一致); ORF4 [Escherichia coli strain B171-8] gi|4
126792|dbj|Baa36750.1| (127アミノ酸のうち40%一致)
に類似 SEQ ID NO: 654： -0.431519, 534, 推定 転写調節タン
パク質, 転写調節タンパク質 例えばUidR [Escherichia
coli] gi|2495429|sp|Q59431|UIDR#ECOLI (123アミノ
酸のうち30%一致) に類似 SEQ ID NO: 655： -0.048747, 440, 推定 multidrug-ef
flux輸送 タンパク質precursor, multidrug-efflux 輸
送 タンパク質前駆体 例えばAcrA [Escherichia coli K
-12] gi|399000|sp|P31223|ACRA#ECOLI (358アミノ酸の
うち51%一致) に類似 SEQ ID NO: 656： -0.159091, 111, 推定 multidrug-ef
flux輸送タンパク質multidrug-efflux輸送タンパク質
例えばAcrB [Escherichia coli K-12] gi|399001|sp|P3
1224|ACRB#ECOLI (974アミノ酸のうち56%一致) に類似 SEQ ID NO: 657： -0.38651, 342, 推定 外膜channelタ
ンパク質, 外膜channelタンパク質 例えばOprM [Pseudo
monas aeruginosa] gi|3184190|dbj|Baa28694.1| (448
アミノ酸のうち43%一致)に類似 SEQ ID NO: 658： -0.231818, 133, 推定 膜輸送タンパ
ク質, 膜輸送タンパク質例えば[Streptomyces coelicol
or A3(2)] gi|6469269|emb|CAB61730.1| (380アミノ酸
のうち38%一致)に類似 SEQ ID NO: 659： -0.434188, 118, 新規, ハイポセテ
ィカルタンパク質 [Xylella fastidiosa] gi|9106817|g
b|aaF84556.1|AE003997#12 (209アミノ酸のうち38%一
致)に類似 SEQ ID NO: 660： -0.471354, 193, B1327#ECOLI gi|17
87587のC-末端部分(224-310/310アミノ酸) (87アミノ酸
のうち33%一致)に類似 SEQ ID NO: 661： -0.156489, 132, B1327#ECOLI gi|17
87587のN-末端部分(22-123/310アミノ酸) (113アミノ酸
のうち62%一致)に類似 SEQ ID NO: 662： -0.247561, 247, transposase (inse
rtion sequence IS629),ｇｉ｜７４４３８６２｜ｐｉｒ
｜｜Ｔ００２４０と同じ SEQ ID NO: 663： -0.355, 141, transposase (inserti
on sequence IS629), gi|7444868|pir||T00241と同じ SEQ ID NO: 664： -0.182639, 145, 推定 調節因子, 調
節タンパク質 例えば調節 タンパク質 CI (235アミノ
酸) [Bacteriophage HK022] gi|1350835|sp|P18680 (66
アミノ酸のうち42%一致)に類似(低い) SEQ ID NO: 665： -0.463487, 850, 推定 調節因子, Cr
o [Bacteriophage HK022] gi|1350553|sp|P18679 (73ア
ミノ酸のうち61%一致)に類似 SEQ ID NO: 666： -0.314679, 110, C-末端部分 (139-2
62 in 262アミノ酸)がYDAU#ECOLI gi|1787622のC-末端
部分 (162-285 / 285アミノ酸) (124アミノ酸のうち79%
一致)に類似 SEQ ID NO: 667： -0.4625, 233, 新規 SEQ ID NO: 668： -0.390688, 248, 新規 SEQ ID NO: 669： 0.20583, 224, 新規 SEQ ID NO: 670： -0.342491, 1133, 新規 SEQ ID NO: 671： -0.326633, 200, 新規, Eアミノ酸
タンパク質 [Bacteriophage P22] gi|418207|sp|Q03544
|VEaa#BPP22のN-末端部分(42アミノ酸のうち88%一致)に
類似 SEQ ID NO: 672： -0.27899, 972, 新規, ハイポセティ
カルタンパク質 [Bacteriophage H19J] gi|4490348|emb
|CAB38711.1| (54アミノ酸のうち70%一致)に部分的に類
似; part of Gp45 [Bacteriophage N15] gi|7521552|pi
r||T13131 (47アミノ酸のうち57%一致)に部分的に類似 SEQ ID NO: 673： -0.308808, 194, possible methyltr
ansferase, methyltransferases 例えばcytosine-speci
fic methyltransferase XorII [Xanthomonas oryzae p
v.] gi|1709171|sp|P52311|MTX2#XANOR (365アミノ酸の
うち40%一致)に類似 SEQ ID NO: 674： -0.40473, 297, 新規, ハイポセティ
カルタンパク質 HI0983[Haemophilus influenzae] gi|1
074592|pir||D64163 (138アミノ酸のうち26%一致)に類
似(低い) SEQ ID NO: 675： -0.432143, 169, 新規 SEQ ID NO: 676： -0.448193, 167, 新規, Orf79 [Bact
eriophage D3] gi|8895177|gb|aaF80835.1| (199アミノ
酸のうち36%一致)に類似 SEQ ID NO: 677： -1.706667, 61, 新規, ハイポセティ
カルタンパク質 例えばYbcO [Escherichia coli crypti
c prophage DLP12] gi|7467043|pir||C64787 (96アミノ
酸のうち57%一致); Gp66 [Bacteriophage HK97] gi|690
1638|gb|aaF31141.1| (94アミノ酸のうち56%一致)に類
似 SEQ ID NO: 678： -0.237063, 144, 推定 aniterminato
r, antiterminatorタンパク質Q [Bacteriophage 21] gi
|4539484|emb|CAB39993.1| (168アミノ酸のうち22%一
致)に類似(低い) SEQ ID NO: 679： -0.446341, 83, 新規, 推定 TerB タ
ンパク質 例えば[Deinococcus radiodurans] gi|747369
0|pir||C75302 (129アミノ酸のうち26%一致)に類似 SEQ ID NO: 680： -0.403175, 127, 新規, GTGスタート SEQ ID NO: 681： 0.010435, 116, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage 933W] gi|45854
19|gb|aaD25447.1|AF125520#42 (613アミノ酸のうち53%
一致)に類似 SEQ ID NO: 682： -0.445312, 513, 推定 holinタンパ
ク質 (host cell lysis),holinタンパク質 例えば[Bact
eriophage 933W] gi|4499808|emb|CAB39307.1| (71アミ
ノ酸のうち91%一致)に類似 SEQ ID NO: 683： -0.57037, 55, 新規, ハイポセティ
カルタンパク質 [Escherichia coli] gi|3183262|sp|P7
6160|YDFR#ECOLI (74アミノ酸のうち43%一致)に類似 SEQ ID NO: 684： -0.313158, 495, endolysin (host c
ell lysis), endolysins例えば[Bacteriophage 933W] g
i|4335686|gb|aaD17382.1| (177アミノ酸のうち96%一
致)に類似 SEQ ID NO: 685： -0.652681, 318, 推定 antiリプレッ
サー, 推定 antiリプレッサー [Bacteriophage 933W] g
i|4585423|gb|aaD25451.1|AF125520#46 (189アミノ酸の
うち100%一致)と同じ; N-末端部分(1-126アミノ酸)がan
tiリプレッサータンパク質 Ant [Bacteriophage P22] g
i|131843|sp|P03037|RANT#BPP22 (126アミノ酸のうち49
%一致 に類似 SEQ ID NO: 686： -0.24433, 195, endoペプチダーゼ
(host cell lysis), endoペプチダーゼ 例えば[Bacter
iophage VT2-Sa] gi|5881639|dbj|Baa84330.1| (155ア
ミノ酸のうち100%一致)に類似 SEQ ID NO: 687： -0.965741, 109, 新規, ハイポセテ
ィカルタンパク質 [Escherichia coli] gi|1778472|gb|
aaB40755.1| (67アミノ酸のうち70%一致)； ハイポセテ
ィカルタンパク質 [Salmonella dublin] gi|3511132|gb
|aaC33722.1| (49アミノ酸のうち70%一致)に類似 SEQ ID NO: 688： -0.397973, 297, 推定 DNase, gp30
(DNase) [Bacteriophagephi-C31] gi|1107475|emb|Caa6
2587.1| (85アミノ酸のうち28%一致)に類似(低い); Ter
F-related タンパク質 [Deinococcus radiodurans] gi|
7473956|pir||C75599 (72アミノ酸のうち33%一致) に類
似(低い) SEQ ID NO: - ： -0.413248, 235, 新規 SEQ ID NO: - ： 0.280303, 67, 推定 terminase small
subunit, phage terminase small subunits 例えば[Ba
cillus subtilis PBSX] gi|1722886|sp|P39785|XTMA#BA
CSU (52アミノ酸のうち34%一致)に類似 SEQ ID NO: 1641： -0.383784, 297, 推定 terminase l
arge subunit, phage ハイポセティカルタンパク質, 例
えばphage D3 terminase-様タンパク質 [Haemophilus i
nfluenzae] gi|6739656|gb|aaF27357.1|AF198256#11 (5
7アミノ酸のうち22%一致)に類似 SEQ ID NO: 1642： -0.942593, 109, phage major head
タンパク質/prohead プロテアーゼ, C-末端部分がmajo
r head タンパク質 例えば[Mycobacterium phageL5] gi
|465114|sp|Q05223|VG17#BPML5 (306アミノ酸のうち22%
一致)に類似; N-末端部分が推定 prohead プロテアーゼ
例えば[Rhodobacter capsulatus] gi|6467535|gb|aaF1
3181.1|AF181080#3 (133アミノ酸のうち30%一致)に類
似; 推定 prohead プロテアーゼ [Rhodobacter capsula
tus] gi|6467535|gb|aaF13181.1|AF181080#3 (133アミ
ノ酸のうち30%一致)に類似, GTGスタート SEQ ID NO: - ： -0.615396, 657, 新規 SEQ ID NO: 1419： 0.067253, 285, 推定 portalタンパ
ク質, phage portal タンパク質 例えば[Bacteriophage
D3] gi|5059250|gb|aaD38955.1| (366アミノ酸のうち2
4%一致)に類似 SEQ ID NO: 1420： -0.121505, 94, 新規 SEQ ID NO: 1421： -0.211215, 215, 新規 SEQ ID NO: 1422： 0.150397, 253, 推定 phage head-t
ail adaptor, head-tailadaptors 例えば[Bacteriophag
e HK97] gi|6901597|gb|aaF31100.1| (111アミノ酸のう
ち44%一致)に類似 SEQ ID NO: 1423： 0.99049, 327, 新規, phage ハイポ
セティカルタンパク質例えばGp10 [Bacteriophage HK9
7] gi|6901598|gb|aaF31101.1| (148アミノ酸のうち75%
一致) に類似 SEQ ID NO: 1424： -0.024118, 341, 新規, Gp11 [Bact
eriophage HK97] gi|6901599|gb|aaF31102.1| (113アミ
ノ酸のうち49%一致)に類似 SEQ ID NO: 1425： 0.580303, 67, major tail subuni
t, major tail subunit [Bacteriophage HK97] gi|6901
588|gb|aaF31091.1|AF069529#4 (234アミノ酸のうち67%
一致)に類似 SEQ ID NO: 338： -0.622872, 377, 推定 tail assembl
y chaperon, tail assembly chaperon Gp14 [Bacteriop
hage HKJ97] gi|6901600|gb|aaF31103.1| (124アミノ酸
のうち62%一致)に類似 SEQ ID NO: 339： -0.239024, 83, 新規, Gp14 [Bacter
iophage HK97] gi|6901601|gb|aaF31104.1|のC-末端部
分(94アミノ酸のうち60%一致)に類似,probably produce
d by translational frameshift SEQ ID NO: 340： -0.7548, 824, 推定 tail length ta
pe measure タンパク質,tail length tape measure タ
ンパク質 例えば[Bacteriophage HK97] gi|6901589|gb|
aaF31092.1|AF069529#5 (1022アミノ酸のうち52%一致)
に類似 SEQ ID NO: 341： 0.230159, 64, 推定 tail componen
t, minor tail タンパク質 例えばGpM [Bacteriophage
lambda] gi|138845|sp|P03737|VMTM#LAMBD (110アミノ
酸のうち45%一致)に類似, GTGスタート SEQ ID NO: 342： -0.180645, 63, 推定 tail componen
t, minor tail タンパク質 例えばGpL [Bacteriophage
lambda] gi|138844|sp|P03738|VMTL#LAMBD (232アミノ
酸のうち75%一致)に類似 SEQ ID NO: 343： -0.133766, 78, 推定 tail assembl
y, tail assemblyタンパク質 例えばGpK [Bacteriophag
e lambda] gi|6901605|gb|aaF31108.1| (226アミノ酸の
うち35%一致)に類似 SEQ ID NO: 344： -0.166667, 136, 推定 tail assembl
y, tail assemblyタンパク質 例えばGpI [Bacteriophag
e lambda] gi|139637|sp|P03730|VTAI#LAMBD (224アミ
ノ酸のうち69%一致)に類似 SEQ ID NO: 345： -0.626389, 73, 新規 SEQ ID NO: 346： -0.679259, 136, 推定 superoxide d
ismutase, copper/zinc-superoxide dismutases 例えば
[Salmonella typhimurium] gi|2462699|emb|Caa73588.1
| (175アミノ酸のうち58%一致)に類似 SEQ ID NO: 347： -0.498667, 76, 推定 phage host sp
ecificityタンパク質, host specificityタンパク質 例
えばGpJ [Bacteriophage lambda] gi|138412|sp|P03749
|VHSJ#LAMBD (1164アミノ酸のうち70%一致)に類似 SEQ ID NO: 348： -0.345355, 184, 外膜タンパク質 例
えばLom タンパク質 [Bacteriophage P-EibA] dad|AF15
1091-2|aaF63231.1| (199アミノ酸のうち68%一致)に類
似 SEQ ID NO: 349： -0.672832, 347, 推定 tail fiber
タンパク質, 推定 tail fiberタンパク質 例えば[Bacte
riophage 933W] gi|4585436|gb|aaD25464.1|AF125520#5
9 (AF125520) (233アミノ酸のうち34%一致)に類似, GTG
スタート SEQ ID NO: 350： -0.670588, 222, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585437|g
b|aaD25465.1|AF125520#60 (129アミノ酸のうち94%一
致)に類似, GTGスタート SEQ ID NO: 351： -0.268932, 104, 新規, ORF4 [Esche
richia coli strain B171-8] gi|4126792|dbj|Baa3675
0.1| (116アミノ酸のうち35%一致); ORF2 [Escherichia
coli strain B171-8] gi|4126790|dbj|Baa36748.1| (1
71アミノ酸のうち28%一致)に類似 SEQ ID NO: 352： -0.120755, 54, 新規, ORF4 [Escher
ichia coli strain B171-8] gi|4126792|dbj|Baa36750.
1| (135アミノ酸のうち91%一致); ORF2 [Escherichia c
oli strain B171-8] gi|4126790|dbj|Bアミノ酸36748.1
| (205アミノ酸のうち43%一致)に類似 SEQ ID NO: 353： -0.368651, 253, 新規, ORF4 [Esche
richia coli B171-8] gi|4126792|dbj|Baa36750.1| (13
5アミノ酸のうち41%一致); ORF2 [Escherichia coli st
rain B171-8] gi|4126790|dbj|Baa 36748.1| (126アミ
ノ酸のうち36%一致)に類似 SEQ ID NO: 354： 0.292857, 71, YDBL#ECOLI gi|17876
48 (109アミノ酸のうち71%一致)に類似, しかしN-末とC
-末が異なる SEQ ID NO: 355： 0.012941, 86, 推定 ABC-type輸送タ
ンパク質, ABC-type輸送タンパク質 YdbA.2 [Escheric
hia coli] gi|7465766|pir||C48399のN-末端部分 (1-11
28 / 2020アミノ酸) (1011アミノ酸のうち49%一致)に類
似 SEQ ID NO: 356： -1.156522, 93, 推定 ABC-type 輸送
タンパク質, ABC-type輸送タンパク質 YdbA.2 [Escher
ichia coli] gi|7465766|pir||C48399のC-末端部分(122
0-2020/2020アミノ酸) (806アミノ酸のうち77%一致)に
類似 SEQ ID NO: 357： -0.396839, 349, 新規 SEQ ID NO: 358： -0.287395, 120, 新規 SEQ ID NO: 359： -0.428409, 177, 新規 SEQ ID NO: 360： 0.049057, 107, 新規 SEQ ID NO: 361： -0.469602, 353, 新規, Vgr タンパ
ク質 例えばVgrE タンパク質 [Escherichia coli] gi|2
920625|gb|aaC32465.1| (702アミノ酸のうち98%一致)に
類似 SEQ ID NO: 362： -0.206969, 618, Rhs タンパク質, R
hs coreタンパク質 例えばRhsD [Escherichia coli] gi
|1786706 (1281アミノ酸のうち92%一致)に類似 (Conser
ved in E.coli K-12) SEQ ID NO: 363： 0.095775, 72, 新規, IpaHタンパク
質 IPA7#SHIFL gi|124813|sp|P18014 (120アミノ酸のう
ち35%一致); YDDK#ECOLI gi|3183258|sp|P76123 (100ア
ミノ酸のうち32%一致) に類似(低い) SEQ ID NO: 364： -0.074561, 115, 外膜 porin前駆体
例えばNMPC#ECOLI gi|1786765 (343アミノ酸のうち67%
一致) に類似, しかしN-末端が異なる SEQ ID NO: 365： -0.466667, 178, 新規, GTGスタート SEQ ID NO: 366： -0.283069, 190, 推定 fimbrial cha
peroneタンパク質前駆体, fimbrial chaperoneタンパク
質前駆体 例えばFocC [Escherichia coli] gi|1169720|
sp|P46008|FOCC#ECOLI (206アミノ酸のうち67%一致)に
類似 SEQ ID NO: 367： -0.472903, 156, 推定 type 1 fimbr
ialタンパク質前駆体, type 1 fimbrialタンパク質前駆
体 例えば[Escherichia coli] gi|729528|sp|P04128|FM
1A#ECOLI (186アミノ酸のうち64%一致)に類似 SEQ ID NO: 368： 0.214754, 62, 新規, GTGスタート SEQ ID NO: 369： -0.717334, 76, 推定 調節因子, ara
C-family 転写調節因子AdpA [Streptomyces coelicolor
A3(2)] gi|7544056|emb|CAB87229.1 (316アミノ酸のう
ち41%一致)に類似 SEQ ID NO: 370： -0.468595, 122, damage-inducible
タンパク質, damage-inducible タンパク質 例えばDinI
[Escherichia coli] gi|2498305|sp|Q47143|DINI#ECOL
I (72アミノ酸のうち36%一致)に類似 SEQ ID NO: 371： -1.029787, 48, 新規, ハイポセティ
カルタンパク質 例えばORF4 [Escherichia coli] gi|41
26792|dbj|Baa36750.1| (131アミノ酸のうち43%一致);
ORF2 [Escherichia coli] gi|4126790|dbj|Baa36748.1|
(126アミノ酸のうち35%一致)に類似 SEQ ID NO: 372： -0.648128, 188, 新規, ハイポセテ
ィカルタンパク質 例えばORF4 [Escherichia coli] gi|
4126790|dbj|Baa36748.1| (206アミノ酸のうち43%一
致); ORF2 [Escherichia coli] gi|4126792|dbj|Baa367
50.1| (135アミノ酸のうち91%一致)に類似 SEQ ID NO: 373： -0.117179, 554, 新規, ハイポセテ
ィカルタンパク質 例えばORF4 [Escherichia coli] gi|
4126792|dbj|Baa36750.1| (116アミノ酸のうち34%一
致); ORF2 [Escherichia coli] gi|4126790|dbj|Baa367
48.1| (171アミノ酸のうち28%一致)に類似 SEQ ID NO: 374： -0.148992, 646, 新規, ハイポセテ
ィカルタンパク質[Bacteriophage 933W] gi|4585437|gb
|aaD25465.1|AF125520#60 (89アミノ酸のうち93%一致)
に類似 SEQ ID NO: 375： -0.831147, 62, 推定 tail fiber タ
ンパク質, 推定 tail fiberタンパク質 [Bacteriophage
933W] gi|4585436|gb|aaD25464.1|AF125520#59のC-末
端部分 (92アミノ酸のうち100%一致)に類似, GTGスター
ト, probably disrupted SEQ ID NO: 376： -0.483469, 860, 推定 tail fiberタ
ンパク質, tail fiberタンパク質 例えばGp37 [Escheri
chia coli] gi|7466858|pir||G64887のN-末端部分(271
アミノ酸の57うち%一致); orf-401 [Bacteriophage lam
bda] gi|140053|sp|P03764|Y401#LAMBD (269アミノ酸の
うち56%一致)に類似, probably interrupted SEQ ID NO: 377： -0.061111, 109, 推定 outer host
膜タンパク質前駆体, Lom-様 タンパク質 例えば[proph
age P-EibA] gi|7532789|gb|aaF63231.1|AF151091#2 (1
99アミノ酸のうち68%一致); Lom [Bacteriophage lambd
a] gi|138693|sp|P03701|VLOM#LAMBD (199アミノ酸のう
ち44%一致)に類似 SEQ ID NO: 378： -0.192241, 117, phage tailタンパ
ク質 (host specificityタンパク質), host specificit
yタンパク質 例えばGpJ [Bacteriophage lambda]gi|138
412|sp|P03749|VHSJ#LAMBD (1158アミノ酸のうち65%一
致)に類似 SEQ ID NO: 379： -0.512838, 149, tail assemblyタン
パク質, tail assemblyタンパク質 例えばGpI [Bacteri
ophage lambda] gi|139637|sp|P03730|VTAI#LAMBD (224
アミノ酸のうち69%一致)に類似 SEQ ID NO: 380： 0.172807, 115, tail assemblyタン
パク質, tail assemblyタンパク質 例えばGpK [Bacteri
ophage lambda gi|139638|sp|P03729|VTAK#LAMBD (174
アミノ酸のうち85%一致)に類似 SEQ ID NO: 381： -0.337367, 282, minor tail compon
ent, minor tail タンパク質 例えばGpL [Bacteriophag
e lambda] gi|138844|sp|P03738|VMTL#LAMBD (232アミ
ノ酸のうち76%一致)に類似 SEQ ID NO: 382： -0.296774, 125, minor tail compon
ent, minor tailタンパク質 例えばGpM [Bacteriophage
lambda] gi|138845|sp|P03737|VMTM#LAMBD (109アミノ
酸のうち79%一致)に類似ＳＥＱ ＩＤ ＮＯ： ３８
３： -0.091398, 94, tail length determination, tai
l length tape measureタンパク質前駆体 例えばGpH [B
acteriophage lambda] gi|138843|sp|P03736|VMTH#LAMB
D (870アミノ酸のうち51%一致)に類似 SEQ ID NO: 384： -0.319298, 1027, minor tail compo
nent, minor tail タンパク質 例えばGpG-T [Bacteriop
hage lambda] gi|7429179|pir||TLBPTL (134アミノ酸の
うち67%一致)に類似, produced by translational fram
eshift SEQ ID NO: 385： -0.624779, 114, minor tail compon
ent, minor tailタンパク質 例えばGpG [Bacteriophage
lambda] gi|138842|sp|P03734|VMTG#LAMBD (140アミノ
酸のうち43%一致)に類似 SEQ ID NO: 386： -0.477931, 146, 新規, おそらくタ
ンパク質 V [Bacteriophage lambda]に相当 SEQ ID NO: 387： -0.276079, 1159, minor tail compo
nent, minor tailタンパク質 GpU [Bacteriophage lamb
da] gi|138847|sp|P03732|VMTU#LAMBD (131アミノ酸の
うち80%一致)に類似 SEQ ID NO: 388： -0.29799, 200, minor tail compone
nt, minor tail タンパク質 例えばGpZ [Bacteriophage
lambda] gi|138849|sp|P03731|VMTZ#LAMBD (177アミノ
酸のうち69%一致)に類似 SEQ ID NO: 389： -0.661327, 438, tail attachment
(minor capsidタンパク質), minor capsid ンパク質 例
えばGpFII [Bacteriophage lambda] gi|137575|sp|P037
14|VCF2#LAMBD (117アミノ酸のうち91%一致)に類似 SEQ ID NO: 390： -0.392135, 90, DNA-packaging, DNA
-packagingタンパク質例えばGpFI [Bacteriophage lamb
da] gi|139324|sp|P03709|VPF1#LAMBD (132アミノ酸の
うち98%一致)に類似 SEQ ID NO: 391： 0.522727, 89, major capsidタンパ
ク質, major capsidタンパク質 例えばGpE [Bacterioph
age lambda] gi|116701|sp|P05481|HEAD#BPPH8 (341ア
ミノ酸のうち87%一致)に類似 SEQ ID NO: 392： -0.269369, 112, head decorationタ
ンパク質 (major capsidタンパク質), major capsidタ
ンパク質 例えばGpD [Bacteriophage lambda] gi|13756
6|sp|P03712|VCAD#LAMBD (110アミノ酸のうち99%一致)
に類似 SEQ ID NO: 393： -0.239229, 442, minor capsidタン
パク質前駆体, minor capsidタンパク質前駆体 例えばG
pC [Bacteriophage lambda] gi|137565|sp|P03711|VCAC
#LAMBD (439アミノ酸のうち97%一致) に類似, capsid a
ssemblyタンパク質Nu3-homologを含む SEQ ID NO: 394： -0.247826, 231, portalタンパク質
(minor capsidタンパク質), portalタンパク質 例えばG
pB [Bacteriophage lambda] gi|138762|sp|P03710|VMCB
#LAMBD (533アミノ酸のうち98%一致)に類似 SEQ ID NO: 395： -0.441584, 304, head-to-tail join
ing, head-to-tail joiningタンパク質 例えばGpW [Bac
teriophage lambda] gi|138415|sp|P03727|VHTJ#LAMBD
(68アミノ酸のうち98%一致)に類似 SEQ ID NO: 396： -0.434392, 190, terminase large s
ubunit (DNA-packagingタンパク質), terminase large
subunits 例えばGpA [Bacteriophage lambda] gi|13761
6|sp|P03708|TERL#LAMBD (641アミノ酸のうち97%一致)
に類似, GTGスタート SEQ ID NO: 397： -0.085882, 86, 推定 terminase sma
ll subunit, terminasesmall subunits 例えばNu1 [Bac
teriophage lambda] (180アミノ酸のうち82%一致)に類
似 SEQ ID NO: 398： -0.327551, 99, 新規, ハイポセティ
カルタンパク質 例えば[Escherichia coli] gi|1778472
|gb|aaB40755.1| (53アミノ酸のうち90%一致)に類似 SEQ ID NO: 399： -0.445312, 513, 推定 転写調節因
子, eaeA/bfpA [Escherichia coli] gi|1172431|sp|P43
475|PERC#ECOLIのPerC (BfpW) 転写アクチベーター(87
アミノ酸のうち47%一致)に類似 SEQ ID NO: 400： 0.010435, 116, 推定 リポタンパク
質Rz1前駆体, リポタンパク質Rz1前駆体 例えば[phage
lambda] gi|540738|pir||JN0750 (61アミノ酸のうち70%
一致)に類似 SEQ ID NO: 401： -0.403175, 127, 推定 host cell ly
sis, endoペプチダーゼ例えば[Bacteriophage H-19B] g
i|4335687|gb|aaD17383.1| (150アミノ酸のうち77%一
致)に類似 SEQ ID NO: 402： -0.542391, 93, 新規, ハイポセティ
カルタンパク質 YchG [Escherichia coli] gi|267475|s
p|P30192|YCHG#ECOLI (30アミノ酸のうち80%一致)に部
分的に類似 SEQ ID NO: 403： -0.42, 51, 新規, ハイポセティカル
タンパク質 例えばYchG[Escherichia coli] gi|267475|
sp|P30192|YCHG#ECOLI (60アミノ酸のうち95%一致)に部
分的に類似, GTGスタート SEQ ID NO: 404： -0.364583, 49, 新規, ハイポセティ
カルタンパク質 b1240 [Escherichia coli] gi|7466155
|pir||C64871 (51アミノ酸のうち54%一致)に部分的に類
似

【００２０】３）挿入配列（Insertion Sequence; IS）
を含むタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 405： -0.221861, 216, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881622
|dbj|Baa84313.1|と同じ, しかしスタートが異なる; ハ
イポセティカルタンパク質 [Bacteriophage 933W] gi|4
499790|emb|CAB39289.1| (78アミノ酸のうち85%一致)に
類似 SEQ ID NO: 406： -0.313776, 197, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881623
|dbj|Baa84314.1|と同じ, しかしスタートが異なる; ハ
イポセティカルタンパク質 例えばNinB タンパク質 [Ba
cteriophage 21](147アミノ酸のうち43%一致)に類似 SEQ ID NO: 407： -0.486667, 61, 推定 DNA methylas
e, ハイポセティカルタンパク質 [Bacteriophage VT2-S
a] gi|5881624|dbj|Baa84315.1| (175アミノ酸のうち10
0%一致)と同じ; ハイポセティカルタンパク質 Gp62 [Ba
cteriophage HK97] gi|6901634|gb|aaF31137.1| (175ア
ミノ酸のうち98%一致)に類似; DNA N-6-adenine-methyl
transferase (M.T1) [Enterobacteria phage T1] gi|16
6164|gb|aaA87390.1| (143アミノ酸のうち31%一致) に
類似(低い) SEQ ID NO: 408： -0.175926, 55, 新規, ハイポセティ
カルタンパク質 [Bacteriophage VT2-Sa] gi|5881625|d
bj|Baa84316.1| (60アミノ酸のうち100%一致)と同じ;
ハイポセティカルタンパク質 例えばNinEタンパク質 [B
acteriophage 21]gi|4539480|emb|CAB39989.1| (60アミ
ノ酸のうち98%一致)に類似 SEQ ID NO: 409： -0.017752, 170, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881626
|dbj|Baa84317.1| (57アミノ酸のうち100%一致)と同じ,
GTGスタート SEQ ID NO: 1375： -0.38883, 189, 推定 antiリプレッ
サータンパク質, ハイポセティカルタンパク質 [Bacter
iophage VT2-Sa] gi|5881627|dbj|Baa84318.1| (244ア
ミノ酸のうち100%一致)と同じ; C-末端部分 がantiリプ
レッサータンパク質 Ant [Bacteriophage P22] gi|1318
43|sp|P03037|RANT#BPP22のC-末端部分 (104アミノ酸の
82うち%一致)に類似, N-末端部分がハイポセティカルタ
ンパク質 [Bacteriophage TP901-1] gi|2924237|emb|Ca
a74615.1|のN-末端部分 (119アミノ酸のうち42%一致)に
類似 SEQ ID NO: 1376： -0.209115, 374, DNA-結合タンパク
質, Roi [BacteriophageVT2-Sa] gi|5881628|dbj|Baa84
319.1|と同じ, しかしスタートが異なる;Roiタンパク質
例えば[Enterobacteria phage HK022] gi|1197729|gb|
aa C48863.1| (242アミノ酸のうち82%一致)に類似 SEQ ID NO: 1377： 0.177508, 1028, 新規, ハイポセテ
ィカルタンパク質 orf15[Bacteriophage 933W] gi|4499
798|emb|CAB39297.1| (201アミノ酸のうち100%一致)と
同じ, ハイポセティカルタンパク質 例えばNinGタンパ
ク質 [Bacteriophage 21] gi|4539482|emb|CAB39991.1|
(201アミノ酸のうち94%一致)に類似 SEQ ID NO: 1378： -0.144201, 458, 新規, ハイポセテ
ィカルタンパク質 orf16[Bacteriophage 933W] gi|4499
799|emb|CAB39298.1|(64アミノ酸のうち100%一致)と同
じ; ハイポセティカルタンパク質 例えばNin68 [Bacter
iophage lambda]gi|9626304|ref|NP#040640.1|(60アミ
ノ酸のうち80%一致)に類似 SEQ ID NO: 1379： 0.890181, 388, antiterminationタ
ンパク質 Q, antitermination Qタンパク質 [Bacteriop
hage 933W] gi|4585416|gb|aaD25444.1|AF125520#39と
同じ, しかしスタートが異なる; antitermination Qタ
ンパク質 例えば[Bacteriophage H-19B] gi|2668768|gb
|aaD04655.1| (144アミノ酸のうち96%一致)に類似 SEQ ID NO: - ： -0.090909, 221, 新規, ハイポセティ
カルタンパク質 [Bacterｉｏｐｈａｇｅ Ｐ２７］ ｇ
ｉ｜８３４６５７０｜ｅｍｂ｜ＣＡＢ９３７６３．１｜
（３７アミノ酸のうち89%一致) に部分的に類似, TTG
スタート SEQ ID NO: 1676： 0.087912, 92, Shiga toxin 2 subu
nit A, gi|1351074|sp|P09385|SLTA#BP933と同じ; ECs1
908: Comp.(1899924-1900292), -0.25, 123, Shiga tox
in 2 subunit B gi|134538|sp|P09386|SLTB#BP933と同
じ SEQ ID NO: 1644： -0.397973, 297, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585419|g
b|aaD25447.1|AF125520#42のN-末端部分 (557アミノ酸
のうち100%一致)と同じ; ハイポセティカルタンパク質
例えばYjhS [Shigella dysenteriae] gi|6759965|gb|aa
F28123.1|AF153317#19のN-末端部分 (554アミノ酸のう
ち78%一致)に類似 SEQ ID NO: 1645： -0.965741, 109, transposase (Orf
B) (insertion sequenceIS629), gi|7443862|pir||T002
40と同じ SEQ ID NO: 1681： -0.893204, 104, transposase (Orf
A) (insertion sequenceIS629), gi|7444868|pir||T002
41 (108アミノ酸のうち100%一致)と同じ SEQ ID NO: - ： -0.342857, 85, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|4499806|emb
|CAB39305.1| (59アミノ酸のうち100%一致)と同じSEQ I
D NO: - ： -0.577099, 263, 新規, ハイポセティカル
タンパク質 [Bacteriophage 933W] gi|4585420|gb|aaD2
5448.1|AF125520#43 (148アミノ酸のうち100%一致)と同
じ SEQ ID NO: 877： -0.830769, 79, 推定 holinタンパク
質, タンパク質 [Bacteriophage VT2-Sa] gi|5881636|d
bj|Baa84327.1|と同じ; 推定 holinタンパク質例えば[S
higella dysenteriae] gi|6759967|gb|aaF28125.1|AF15
3317#21 (71アミノ酸のうち95%一致)に類似 SEQ ID NO: 878： -0.5, 141, endolysin, 推定 endoly
sin [Bacteriophage 933W] gi|4585422|gb|aaD25450.1|
AF125520#45 (177アミノ酸のうち100%一致)と同じ;推定
endolysins 例えば[Bacteriophage H-19B] gi|4335686
|gb|aaD17382.1|(177アミノ酸のうち93%一致)に類似 SEQ ID NO: 879： -1.08, 71, 推定 antiリプレッサー
タンパク質, 推定 antiリプレッサータンパク質 [Bacte
riophage 933W] gi|4585423|gb|aaD25451.1|AF125520#4
6と同じ; antiリプレッサータンパク質Ant [Bacterioph
age P22] gi|131843|sp|P03037|RANT#BPP22 (121アミノ
酸のうち49%一致)に類似 SEQ ID NO: 880： -0.375862, 88, 推定 endoペプチダ
ーゼ, endoペプチダーゼ[Bacteriophage 933W] gi|4585
424|gb|aaD25452.1|AF125520#47 (154アミノ酸のうち10
0%一致)と同じ; endoペプチダーゼ 例えばRz [Bacterio
phage lambda] gi|119368|sp|P00726|ENPP#LAMBD (154
アミノ酸のうち72%一致)に類似 SEQ ID NO: 881： -0.477359, 54, 推定 リポタンパク
質Rz1前駆体, 推定 Rz1タンパク質前駆体 [Bacteriopha
ge 933W] gi|4585425|gb|aaD25453.1|AF125520#48(61ア
ミノ酸のうち100%一致)と同じ; リポタンパク質Rz1前駆
体 [Bacteriophage lambda] gi|1017781|gb|aaC48862.1
| (61アミノ酸のうち72%一致)に類似 SEQ ID NO: 882： -0.293827, 82, Borタンパク質前駆
体, [Bacteriophage 933W] gi|4585426|gb|aaD25454.1|
AF125520#49 (97アミノ酸のうち100%一致)と同じ;Borタ
ンパク質前駆体 [Bacteriophage lambda] gi|137520|sp
|P26814|VBOR#LAMBD (97アミノ酸のうち96%一致)に類似 SEQ ID NO: 883： -0.305483, 384, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881640
|dbj|Baa84331.1| (75アミノ酸のうち85%一致)に類似 SEQ ID NO: 884： -0.434955, 330, 推定 small subuni
t terminase, 推定 small subunit terminase [Bacteri
ophage 933W] gi|4585427|gb|aaD25455.1|AF125520#50
(268アミノ酸のうち100%一致)と同じ SEQ ID NO: 885： -0.576025, 464, 推定 terminase la
rge subunit, 推定 terminase large subunit [Bacteri
ophage 933W] gi|4585428|gb|aaD25456.1|AF125520#51
(568アミノ酸のうち100%一致)と同じ SEQ ID NO: 886： -0.238694, 200, 推定 portalタンパ
ク質, 推定 portalタンパク質 [Bacteriophage 933W] g
i|4585429|gb|aaD25457.1|AF125520#52 (714アミノ酸の
うち100%一致)と同じ SEQ ID NO: 887： -0.438542, 97, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|4585430|gb|
aaD25458.1|AF125520#53 (335アミノ酸のうち100%一致)
と同じ SEQ ID NO: 888： -0.264131, 185, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585431|g
b|aaD25459.1|AF125520#54 (404アミノ酸のうち100%一
致)と同じ SEQ ID NO: 889： -0.237063, 144, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585432|g
b|aaD25460.1|AF125520#55 (129アミノ酸のうち100%一
致)と同じ SEQ ID NO: 890： 1.472727, 56, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|4585433|gb|
aaD25461.1|AF125520#56と同じ, しかしスタートが異な
る SEQ ID NO: 891： -0.255915, 618, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585434|g
b|aaD25462.1|AF125520#57と同じ, しかしスタートが異
なる SEQ ID NO: 892： 0.052113, 72, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|4585435|gb|
aaD25463.1|AF125520#58 (216アミノ酸のうち100%一致)
と同じ SEQ ID NO: 893： -0.046491, 115, 推定 tail fiberタ
ンパク質, 推定 tail fiberタンパク質 [Bacteriophage
933W] gi|4585436|gb|aaD25464.1|AF125520#59(645ア
ミノ酸のうち100%一致)と同じ SEQ ID NO: 894： -0.466667, 178, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585437|g
b|aaD25465.1|AF125520#60と同じ, しかしスタートが異
なる SEQ ID NO: 895： -0.283069, 190, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585438|g
b|aaD25466.1|AF125520#61と同じ, しかしスタートが異
なる SEQ ID NO: 896： -0.472903, 156, 新規 [推定 外膜タ
ンパク質; OMP], TTG スタート SEQ ID NO: 897： -0.717334, 76, 新規 [periplasmi
c], ハイポセティカルタンパク質 [Bacteriophage 933
W] gi|4585439|gb|aaD25467.1|AF125520#62 (567アミノ
酸のうち100%一致) と同じ; N-末端部分が ハイポセテ
ィカルタンパク質 [Bacteriophage P-EibD] gi|7523538
|gb|aaF63043.1|AF151675#5 (147アミノ酸のうち98%一
致)に類似, GTGスタート SEQ ID NO: 898： -0.468595, 122, 推定 tail tip fib
erタンパク質, ハイポセティカルタンパク質 [Bacterio
phage 933W] gi|4585440|gb|aaD25468.1|AF125520#63
(422アミノ酸のうち100%一致)と同じ; tail tip fiber
タンパク質 gp21 [phage N15] gi|7444604|pir||T13107
(381アミノ酸のうち24%一致)に類似(低い) SEQ ID NO: 899： -1.029787, 48, 新規 [推定 外膜タ
ンパク質; OMP], ハイポセティカルタンパク質 [Bacter
iophage 933W] gi|4585441|gb|aaD25469.1|AF125520#64
と同じ, しかしスタートが異なる, TTGスタート SEQ ID NO: 900： -0.648128, 188, 新規 [推定 外膜タ
ンパク質; OMP], ハイポセティカルタンパク質 [Bacter
iophage 933W] gi|4585442|gb|aaD25470.1|AF125520#65
(205アミノ酸のうち100%一致)と同じ SEQ ID NO: 901： -0.117179, 554, 推定 外膜前駆体,
推定 Lom前駆体 [Bacteriophage 933W] gi|4585443|gb|
aaD25471.1|AF125520#66 (244アミノ酸のうち100%一致)
と同じ; 外膜タンパク質rck [Salmonella typhimurium]
gi|282013|pir||A43309 (172アミノ酸のうち35%一致);
外膜タンパク質Lom前駆体 gi|138693|sp|P03701|VLOM#
LAMBD (167アミノ酸のうち35%一致); ail gene product
s 例えば[Yersinia pseudotuberculosis] gi|5902750|s
p|Q56957|AIL#YERPS (241アミノ酸のうち32%一致); vir
ulence タンパク質pagC前駆体 [Salmonella typhimuriu
m]gi|129558|sp|P23988|PAGC#SALTY (180アミノ酸のう
ち29%一致)に類似 SEQ ID NO: 902： -0.148992, 646, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585444|g
b|aaD25472.1|AF125520#67 (133アミノ酸のうち100%一
致)と同じ SEQ ID NO: 903： -0.831147, 62, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|4585445|gb|
aaD25473.1|AF125520#68 (218アミノ酸のうち100%一致)
に類似 SEQ ID NO: 904： -0.482819, 455, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585446|g
b|aaD25474.1|AF125520#69 (148アミノ酸のうち100%一
致)と同じ SEQ ID NO: 905： -0.420639, 408, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585447|g
b|aaD25475.1|AF125520#70 (83アミノ酸のうち100%一
致)と同じ SEQ ID NO: 906： -0.063889, 109, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585448|g
b|aaD25476.1|AF125520#71 (421アミノ酸のうち100%一
致)と同じ SEQ ID NO: 907： -0.171552, 117, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585449|g
b|aaD25477.1|AF125520#72 (2793アミノ酸のうち99%一
致)に類似 SEQ ID NO: 908： -0.512838, 149, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585450|g
b|aaD25478.1|AF125520#73と同じ, しかしスタートが異
なる SEQ ID NO: 909： 0.189474, 115, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|9632540|ref
|NP#049534.1| (114アミノ酸のうち100%一致)と同じ;
ハイポセティカルタンパク質 例えばygiW タンパク質前
駆体 [Escherichia coli] gi|1723887|sp|P52083|YGIW#
ECOLI (93アミノ酸のうち53%一致)に類似 SEQ ID NO: 910： -0.313446, 239, MokW タンパク質
(prophage maintenance;modulation of host cell kill
ing), MokW [Bacteriophage 933W] gi|4585453|gb|aaD2
5481.1|AF125520#76 (70アミノ酸のうち100%一致)と同
じ; GelF [Escherichia coli] gi|1786200|gb|aaC7312
9.1| (69アミノ酸のうち73%一致)に類似 SEQ ID NO: 911： -0.276613, 125, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585454|g
b|aaD25482.1|AF125520#77と同じ, しかしスタートが異
なる SEQ ID NO: 912： -0.091398, 94, 新規, ハイポセティ
カルタンパク質 [Bacteriophage VT2-Sa] gi|5881668|d
bj|Baa84359.1| (219アミノ酸のうち100%一致)と同じ;
ハイポセティカルタンパク質 [Bacteriophage 933W] gi
|4585455|gb|aaD25483.1|AF125520#78のC-末端部分(219
アミノ酸のうち100%一致)と同じ SEQ ID NO: 913： -0.343275, 1027, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881669
|dbj|Baa84360.1|と同じ, しかしスタートが異なる; ハ
イポセティカルタンパク質 [Bacteriophage 933W] gi|7
649907|dbj|Baa94185.1| (72アミノ酸のうち92%一致);
ハイポセティカルタンパク質 例えば[Bacteriophage VT
2-Sa] gi|4585386|gb|aaD25414.1|AF125520#9 (68アミ
ノ酸のうち92%一致)に類似 SEQ ID NO: 914： -0.624779, 114, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881670
|dbj|Baa84361.1| (94アミノ酸のうち100%一致)と同じ,
GTGスタート SEQ ID NO: 915： -0.332759, 233, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881671
|dbj|Baa84362.1| (73アミノ酸のうち100%一致)と同じ;
C4-type zinc fingerタンパク質 (TraR family) 例え
ばorf39 [Pseudomonas aeruginosa phage phi CTX] gi|
4063813|dbj|Baa36267.1| (59アミノ酸のうち42%一致)
に類似 SEQ ID NO: 916： -0.407287, 248, 推定 anti-リプレ
ッサータンパク質, ハイポセティカルタンパク質 [Bact
eriophage VT2-Sa] gi|5881672|dbj|Baa84363.1|(209ア
ミノ酸のうち100%一致)と同じ; ハイポセティカルタン
パク質 HI1422 [Haemophilus influenzae Rd] gi|11757
95|sp|P44193|YE22#HAEIN (158アミノ酸のうち40%一
致); 推定 phage anti-リプレッサータンパク質 例えば
[Neisseria meningitidis] gi|7379969|emb|CAB84545.1
| (112アミノ酸のうち49%一致)に類似SEQ ID NO: 917：
0.069027, 227, 新規 SEQ ID NO: 918： -1.014706, 69, おそらくphages N4,
lambda耐性, Rtn membrane associatedタンパク質 [Es
cherichia coli]gi|2498867|sp|P76446|RTN#ECOLI (498
アミノ酸のうち31%一致)に類似 SEQ ID NO: 919： -0.130857, 176, 新規, FidL -Salmo
nella typhimurium gi|4324611|gb|aaD16955.1| (149ア
ミノ酸のうち29%一致)に類似 SEQ ID NO: 920： -0.304721, 1166, 推定 転写アクチ
ベーター, 転写アクチベーター 例えばMarT [Salmonell
a typhimurium] gi|4324612|gb|aaD16956.1| (268アミ
ノ酸のうち28%一致)に類似 SEQ ID NO: 921： -0.308543, 200, 推定 oxidoreducta
se, oxidoreductases 例えば[Escherichia coli] gi|24
92762|sp|P76633|YGCW#ECOLI (257アミノ酸のうち55%一
致)に類似 SEQ ID NO: 922： -0.814127, 362, 推定 chaperone,
ハイポセティカルタンパク質 例えばORF60 [Yersinia p
estis] gi|7467334|pir||T17432 (204アミノ酸のうち48
%一致); chaperoneタンパク質 例えばEcpD [Escherichi
a coli] gi|2506408|sp|P33128|ECPD#ECOLI (185アミノ
酸のうち35%一致)に類似 SEQ ID NO: 923： -0.431859, 114, 新規, ハイポセテ
ィカルタンパク質 例えばORF59 [Yersinia pestis] gi|
4106627|emb|Caa21382.1| (438アミノ酸のうち34%一致)
に類似 SEQ ID NO: 924： -0.114136, 192, 推定 外膜usherタ
ンパク質, ハイポセティカルタンパク質 ORF 58 [Yersi
nia pestis] gi|4106626|emb|Caa21381.1| (824アミノ
酸のうち44%一致); 外膜 usher タンパク質 例えばFimD
[Salmonella typhimurium gi|585135|sp|P37924|FIMD#
SALTY (832アミノ酸のうち32%一致)に類似 SEQ ID NO: 925： -0.282297, 210, 推定 chaperone,
ハイポセティカルタンパク質 ORF57 [Yersinia pestis]
gi|4106625|emb|Caa21380.1| (233アミノ酸のうち39%
一致); chaperoneタンパク質 例えばEcpD [Escherichia
coli] gi|2506408|sp|P33128|ECPD#ECOLI (217アミノ
酸のうち36%一致)に類似 SEQ ID NO: 926： -0.123005, 214, 推定 pilin タンパ
ク質, ハイポセティカルタンパク質 ORF56 [Yersinia p
estis] gi|4106624|emb|Caa21379.1| (185アミノ酸のう
ち36%一致); major pilinタンパク質 例えばSfアミノ酸
[Escherichia coli] gi|4105989|gb|aaD02646.1| (181
アミノ酸のうち32%一致)に類似 SEQ ID NO: - ： -0.309259, 109, 新規 SEQ ID NO: 1488： -0.323145, 1012, 推定 filamentou
s hemagglutinin-様タンパク質, hemagglutinin/hemoly
sin-relatedタンパク質 [Neisseria meningitidis] 例
えばgi|7225719|gb|aa酸F40927.1| (1001アミノ酸のう
ち25%一致); filamentous hemagglutinin B前駆体 [Bor
detella pertussis] gi|78213|pir||S21010(824アミノ
酸のうち20%一致)に類似 SEQ ID NO: - ： -0.353779, 808, 推定 hemolysin ア
クチベーター-related タンパク質, hemolysin アクチ
ベーター-related タンパク質 例えば[Pectobacterium
chrysanthemi] gi|1772622|gb|aaC31980.1| (484アミノ
酸のうち27%一致);ｈｅｍｏｌｙｓｉｎ ａｃｔｉｖａ
ｔｉｏｎタンパク質前駆体 [Serratia marcescens] gi|
123205|sp|P15321|HLYB#SERMA (475アミノ酸のうち24%
一致)に類似 SEQ ID NO: 1608： -0.270213, 142, 推定 holo-[acyl-
carrier タンパク質] synthase, holo-[acyl-carrierタ
ンパク質] synthases 例えば[Campylobacter jejuni] g
i|6968838|emb|CAB73833.1| (121アミノ酸のうち39%一
致)に類似 SEQ ID NO: 1609： -0.224107, 113, 推定 3-oxoacyl-
(acyl carrier タンパク質) reductase, 3-oxoacyl-(ac
yl carrierタンパク質) reductases 例えば[Moritella
marina] gi|7227179|gb|aaF42251.1| (188アミノ酸のう
ち41%一致)に類似 SEQ ID NO: 1610： -0.570629, 144, 推定 (3R)-hydrox
ymyristol-(acyl carrierタンパク質) dehydratase, (3
R)-hydroxymyristol-(acyl carrierタンパク質)dehydra
tases 例えばgi|7190847|gb|aaF39621.1 (158アミノ酸
のうち30%一致)に類似 SEQ ID NO: 1611： -0.0544, 126, 推定 acyl carrier
タンパク質, acyl carrierタンパク質 例えばAcpC [Str
eptococcus agalactiae] gi|4886773|gb|aaD32036.1|AF
093787#4 (86アミノ酸のうち38%一致)に類似 SEQ ID NO: 1409： -0.480057, 703, 推定 aminomethyl
transferase, aminpometyl transferases 例えばgi|74
50600|pir||C75088 (333アミノ酸のうち26%一致)に類似 SEQ ID NO: 1410： -0.678001, 1401, 推定 3-oxoacyl-
[acyl-carrier-タンパク質] synthase, N-末端半分が3-
oxoacyl-[acyl-carrier-タンパク質] synthase (EC 2.
3.1.41) [Bacillus subtilis] gi|7433750|pir||G69842
(393アミノ酸のうち37%一致)に類似; C-末端半分がgi|
7433750|pir||G69842 (439アミノ酸のうち22%一致)に類
似; N-およびC-末端半分nodulationタンパク質 (nodE)
例えば[Rhizobium melilotiプラスミド] gi|128459|sp|
P06230|NODE#RHIMEに類似, この産物は２つの3-oxoacyl
-[acyl-carrier-タンパク質]からなる SEQ ID NO: 1628： -0.368862, 168, 新規, polyketide
synthases 例えば[Streptomyces sp. strain MA6548]
gi|7481905|pir||T17428の部分(201アミノ酸のうち23%
一致) に類似(低い) SEQ ID NO: - ： -0.500273, 367, 新規ＳＥＱ ＩＤ
ＮＯ： − ： -0.253226, 63, 推定 ABC トランスポ
ーター, 推定 ABCトランスポーター(ATP-結合タンパク
質) 例えば[Thermotoga maritima] gi|7445988|pir||H7
2342 (222アミノ酸のうち50%一致)に類似 SEQ ID NO: 1538： -0.112712, 237, 新規 SEQ ID NO: 1539： 0.259358, 188, 新規 [ハイポセテ
ィカル膜タンパク質],ハイポセティカルタンパク質 例
えばBBJ27 [Lyme disease spirocheteプラスミド J/lp3
8] gi|7463605|pir||D70248 (399アミノ酸のうち25%一
致)に類似 SEQ ID NO: 1633： -1.014893, 95, 新規 [periplasmi
c] SEQ ID NO: 1634： -0.166975, 325, 新規 SEQ ID NO: - ： -0.77625, 81, phage integration,
インテグラーゼ 例えば[Vibrio cholerae] gi|498253|g
b|aaC44230.1| (390アミノ酸のうち32%一致) に類似 (P
4 様 インテグラーゼ) SEQ ID NO: 2： -0.123944, 214, 新規, hemagglutinin
main component [Clostridium botulinum phage (type
C)] gi|1346254|sp|P46084|HA33#CLOBO (190アミノ酸
のうち23%一致) に類似(低い) SEQ ID NO: 3： -0.274163, 210, transposase, sBタン
パク質 例えば[Shigelladysenteriae Iso-IS1] gi|6759
959|gb|aa 酸F28117.1|AF153317#13 (129アミノ酸のう
ち72%一致)に類似, GTGスタート SEQ ID NO: 4： -0.112565, 192, 推定 調節タンパク
質, prophage cp4-57調節タンパク質AlpA [Escherichia
coli (strain K-12)] gi|461502|sp|P33997|ALPA#ECOL
I (61アミノ酸のうち52%一致)に類似 SEQ ID NO: 5： -0.320225, 90, 新規, ハイポセティカ
ルタンパク質 b2625 (YfjI) [Escherichia coli K-12]
gi|1723621|sp|P52124|YFJI#ECOLI (444アミノ酸のうち
40%一致)に類似 SEQ ID NO: 6： -0.628261, 93, 新規, ハイポセティカ
ルタンパク質 Cj1244 [Campylobacter jejuni] gi|6968
677|emb|CAB73498.1| (78アミノ酸のうち25%一致) に類
似(低い) SEQ ID NO: 7： -0.642435, 272, 新規, ハイポセティ
カルタンパク質 A153R [Chlorella virus PBCV-1] gi|7
461298|pir||T17644 (365アミノ酸のうち32%一致); DNA
repairタンパク質 rad25 PAB0128 [Pyrococcus abyssi
(strain Orsay)]gi|7514780|pir||A75209 (392アミノ
酸のうち28%一致);推定 helicase(D10 タンパク質) [Ba
cteriophage T5] gi|137606|sp|P11107|VD10#BPT5 (393
アミノ酸のうち27%一致)に類似 SEQ ID NO: 8： -0.313568, 200, 新規, TTGスタート SEQ ID NO: 9： -0.309146, 1160, 新規, L0015 [Esche
richia coli] gi|3414883|gb|aaC31494.1| (512アミノ
酸のうち100%一致)と同じ; ハイポセティカルタンパク
質 例えば[Escherichia coli] gi|3288156|emb|aa1150
9.1| (411アミノ酸のうち99%一致)に類似 SEQ ID NO: 10： 0.086667, 226, 新規, L0014 [Escher
ichia coli] gi|3288157|emb|Caa11510.1| (115アミノ
酸のうち100%一致)と同じ; ハイポセティカルタンパク
質 例えばorf50 [Escherichia coli] gi|6009426|dbj|B
aa84885.1| (107アミノ酸のうち76%一致)に類似 SEQ ID NO: 11： -0.430396, 228, 新規, ハイポセティ
カルタンパク質 例えばL0013 [Escherichia coli] gi|3
414881|gb|aaC31492.1| (133アミノ酸のうち98%一致)に
類似, GTGスタート SEQ ID NO: 12： -0.358621, 233, IS30 transposase
(interrupted), IS30 transposas 例えばi|2851554|sp|
P37246|TRA8#ECOLIのN-末端部分 (101アミノ酸のうち99
%一致)に類似 SEQ ID NO: 13： -0.43945, 110, 推定 transposase, t
ransposases 例えばHp1[Escherichia coli] gi|3661482
|gb|aaC61713.1| (のうち%一致) 98% in 272アミノ酸,
InsB [Shigella dysenteriae] gi|5532467|gb|aaD4475
1.1|AF141323#22(272アミノ酸のうち98%一致)に類似 SEQ ID NO: 14： -0.352643, 871, 推定 complement re
sistanceタンパク質前駆体, リポタンパク質traT前駆体
例えばgi|418135|sp|P32885|TRT1#ECOLI (227アミノ酸
のうち83%一致)に類似, TTGスタート SEQ ID NO: 15： -0.186861, 138, 新規 SEQ ID NO: 16： -0.535714, 141, 新規 SEQ ID NO: 17： -0.34, 251, 新規 SEQ ID NO: 18： -0.155725, 132, 推定 diacylglycero
l キナーゼ, diacylglycerol キナーゼ 例えばgi|12532
1|sp|P00556|KDGL#ECOLI (119アミノ酸のうち76%一致)
に類似 SEQ ID NO: 19： -0.514689, 178, 新規[推定 外膜タン
パク質; OMP], ハイポセティカルタンパク質 例えばyjd
B in basS-adiY intergenic 領域 [Escherichiacoli] g
i|731986|sp|P30845|YJDB#ECOLI (428アミノ酸のうち45
%一致)に類似 SEQ ID NO: 20： -0.476923, 118, 新規, TTGスタート SEQ ID NO: 21： -0.231818, 133, 新規 SEQ ID NO: 22： -0.38651, 342, 新規, GTGスタート SEQ ID NO: 23： -0.159091, 111, urease accessoryタ
ンパク質 UreD, UreD urease-associatedタンパク質 例
えば[Klebsiellaaerogenes] gi|731078|sp|Q09063|URED
#KLEAE (242アミノ酸のうち71%一致)に類似, TTGスター
ト SEQ ID NO: 24： -0.048747, 440, ureas例えばamma su
bunit, urease 例えばamma subunits 例えば[Klebsiell
a pneumoniae] gi|137084|sp|P18316|URE3#KLEAE(100ア
ミノ酸のうち96%一致)に類似 SEQ ID NO: 25： -0.431519, 534, urease beta subuni
t, urease beta subunits 例えば[Klebsiella pneumoni
ae] gi|137077|sp|P18315|URE2#KLEAE (106アミノ酸の
うち82%一致)に類似 SEQ ID NO: 26： -0.526471, 69, urease alpha subuni
t, urease alpha subunits 例えば[Klebsiella pneumon
iae] gi|137070|sp|P18314|URE1#KLEAE (567アミノ酸の
うち90%一致)に類似 SEQ ID NO: 27： -0.582995, 642, urease accessoryタ
ンパク質, UreE ureaseaccessory タンパク質 例えば[K
lebsiellaaerogenes] gi|137095|sp|P18317|UREE#KLEAE
(154アミノ酸のうち80%一致)に類似 SEQ ID NO: 28： -0.439779, 182, urease accessoryタ
ンパク質, UreF ureaseaccessoryタンパク質UreF 例え
ば[Klebsiellaaerogenes] gi|137097|sp|P18318|UREF#K
LEAE (224アミノ酸のうち79%一致)に類似 SEQ ID NO: 29： -0.995946, 75, urease accessoryタ
ンパク質, Ur 例えば urease accessoryタンパク質 例
えば[Klebsiellaaerogenes] gi|137099|sp|P18319|UR例
えば#KLEAE (205アミノ酸のうち90%一致)に類似 SEQ ID NO: 30 -0.961539, 105, 新規, ハイポセティ
カルタンパク質 例えばTnpJ [Shigella flexneri] gi|5
532468|gb|aaD44752.1|AF141323#23 (87アミノ酸のうち
100%一致)に類似

【００２１】４）ファージ由来のタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 31： 0.178689, 62, 推定 antiリプレッサ
ー, antiリプレッサー 例えば[Bacteriophage 933W] gi
|4585423|gb|aaD25451.1|AF125520#46 (189アミノ酸の
うち99%一致)に類似 SEQ ID NO: 32： -0.403947, 153, 推定 host cell lys
is, endolysins 例えば[Bacteriophage 933W] gi|45854
22|gb|aaD25450.1|AF125520#45 (177アミノ酸のうち97%
一致)に類似 SEQ ID NO: 33： -0.280953, 190, 新規, ハイポセティ
カルタンパク質 gi|3183262|sp|P76160|YDFR#ECOLI (74
アミノ酸のうち45%一致)に類似 SEQ ID NO: 34： -0.440678, 178, 推定 holin タンパ
ク質, holins 例えば[Bacteriophage VT2-Sa] gi|58816
36|dbj|Baa84327.1| (68アミノ酸のうち97%一致)に類似 SEQ ID NO: 35： -0.074561, 115, 新規, ハイポセティ
カルタンパク質 [Bacteriophage VT2-Sa] gi|5881634|d
bj|Baa84325.1| (602アミノ酸のうち53%一致)に類似 SEQ ID NO: 36： 0.142647, 69, 新規, tellurium resi
stanceタンパク質 TerBタンパク質 例えば[Deinococcus
radiodurans] gi|7473690|pir||C75302 (129アミノ酸
のうち26%一致)に類似 SEQ ID NO: 37： -0.225415, 603, 推定 転写調節因子,
転写調節因子 例えば[Escherichia coli] gi|586679|s
p|P37638|YHIW#ECOLI (197アミノ酸のうち34%一致)に類
似 SEQ ID NO: 38： -0.247553, 144, ハイポセティカルタ
ンパク質 [Bacteriophage P27] gi|8346569|emb|CAB937
62.1| (63アミノ酸のうち96%一致)に類似 SEQ ID NO: 39： 0.054872, 196, 推定 anti-terminato
r タンパク質, Qタンパク質 [Bacteriophage 21] gi|74
40086|pir||D71566 (45アミノ酸のうち31%一致)に類似 SEQ ID NO: 40： -0.147692, 66, 推定 crossover junc
tion endodeoxyribonuclease, crossover junction end
odeoxyribonuclease [Escherichia coli] gi|2507117|s
p|P40116|RUS#ECOLI (94アミノ酸のうち42%一致); Gp67
[BacteriophageHK97] gi|6901639|gb|aaF31142.1| (98
アミノ酸のうち61%一致)に類似 SEQ ID NO: 41： -0.278804, 185, B1560#ECOLI gi|178
7843 (354アミノ酸のうち85%一致)に類似 SEQ ID NO: 42： -0.439604, 102, 新規 SEQ ID NO: 43： -0.380555, 361, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage 933W] gi|45854
51|gb|aaD25479.1|AF125520#74 (114アミノ酸のうち99%
一致); Ygi [Escherichia coli] gi|1723887|sp|P52083
|YGIW#ECOLI (93アミノ酸のうち53%一致)に類似 SEQ ID NO: 44： -0.741111, 91, prophage maintenanc
eタンパク質; modulation of host cell killing, MokW
[Bacteriophage 933W] gi|4585453|gb|aaD25481.1|AF1
25520#76 (70アミノ酸のうち100%一致) と同じ; Hok/Ge
f family 例えばGef [Escherichia coli] gi|2120017|p
ir||S40540 (69アミノ酸のうち73%一致)に類似 SEQ ID NO: 45： -0.235088, 115, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage 933W] gi|45853
82|gb|aaD25410.1|AF125520#5 (77アミノ酸のうち67%一
致)に類似 SEQ ID NO: 46： 0.222857, 71, 新規, ハイポセティカ
ルタンパク質 [Bacteriophage 933W] gi|4585384|gb|aa
D25412.1|AF125520#7 (72アミノ酸のうち70%一致)に類
似 SEQ ID NO: 47： -0.37027, 186, 新規, GTGスタート SEQ ID NO: 48： 0.130555, 73, 新規, GTGスタート SEQ ID NO: 49： -0.680583, 104, 新規, Gp9 [Bacteri
ophage Mu] gi|6010430|gb|aaF01133.1|AF083977#54 (9
4アミノ酸のうち28%一致)に類似 SEQ ID NO: 50： 0.116, 76, 新規, ハイポセティカル
タンパク質 YdaW [Escherichia coli] gi|3025105|sp|P
76066|YDAW#ECOLI, (143アミノ酸のうち56%一致)に類
似, TTGスタート SEQ ID NO: 51： -0.382796, 94, 推定 複製タンパク
質,のC-末端半分複製タンパク質 14 [Bacteriophage ph
i-80] gi|137937|sp|P14814|VG14#BPPH8 (129アミノ酸
のうち45%一致)に類似 SEQ ID NO: 52： -0.438934, 245, 新規, DnaT [Escher
ichia coli] gi|1361001|pir||S56589のC-末端半分 (95
アミノ酸のうち49%一致)に類似 SEQ ID NO: 53： -0.760454, 221, 新規, ハイポセティ
カルタンパク質 [Escherichia coli] gi|3025103|sp|P7
6064|YDAT#ECOLI (141アミノ酸のうち30%一致)に類似 SEQ ID NO: 54： -0.684726, 348, 推定 調節タンパク
質, Cro [BacteriophageP22] gi|132195|sp|P09964|RCR
O#BPP22 (53アミノ酸のうち39%一致)に類似 SEQ ID NO: 55： -0.385816, 142, 推定 リプレッサー
タンパク質, リプレッサータンパク質 例えばC2 [Bacte
riophage P22] gi|133359|sp|P03035|RPC2#BPP22(の166
アミノ酸うち27%一致)に類似 SEQ ID NO: 56： -0.0975, 81, 新規, ハイポセティカ
ルタンパク質 例えばYdfK[Escherichia coli] gi|14058
4|sp|P29008|YDFA#ECOLI (49アミノ酸のうち87%一致);
YdaF gi|3915965|sp|P38395|YDAF#ECOLIF (49アミノ酸
のうち83%一致)に類似 SEQ ID NO: 57： 0.15977, 175, 新規, ATP-依存性 プ
ロテアーゼ La homolog gi|1708857|sp|P42425|LON2#BA
CSU (95アミノ酸のうち27%一致) に類似(低い) SEQ ID NO: 58： -0.425974, 78, 新規 SEQ ID NO: 59： -0.477358, 213, 新規, TTGスタート SEQ ID NO: 60： -0.526087, 70, 推定 細胞分裂インヒ
ビター, DicB [Escherichia coli] gi|226094|prf||141
0309A (55アミノ酸のうち67%一致)に類似 SEQ ID NO: 61： -0.439535, 87, 新規, ハイポセティ
カルタンパク質 YdfD [Escherichia coli] gi|140587|s
p|P29010|YDFD#ECOLI (62アミノ酸のうち45%一致)に類
似 SEQ ID NO: 62： -0.11129, 63, 推定 exonuclease, ex
onucleases 例えばexodeoxyribonuclease VIII [Escher
ichia coli] gi|2507105|sp|P15032|RECE#ECOLI(350ア
ミノ酸のうち57%一致)に類似 SEQ ID NO: 63： 0.082258, 63, 推定 インテグラーゼ,
推定 インテグラーゼ例えば[Escherichia coli crypti
c prophage] gi|7449509|pir||E64913のN-末端部分 (18
3アミノ酸のうち93%一致)に類似, TTGスタート, probab
ly disrupted SEQ ID NO: 64： -0.580917, 415, 新規 SEQ ID NO: 65： -0.50929, 184, transposase (OrfB),
transposase [Escherichia coli プラスミドpO157 IS6
29] gi|7443862|pir||T00240と同じ SEQ ID NO: 66： -0.175, 85, transposase (OrfA), ハ
イポセティカルタンパク質 [Escherichia coli プラス
ミド pO157 イントロン配列 IS629] gi|7444868|pir||T
00241と同じ SEQ ID NO: 67： -0.397973, 297, 推定 transposase,
推定 transposases 例えば[Yersinia pestis プラスミ
ド pMT1] gi|7447905|pir||T14710 (257アミノ酸のうち
78%一致)に類似, TTGスタート, probably disrupted SEQ ID NO: 68： -0.965741, 109, 新規, L0013 [Esche
richia coli O157:H7 strain EDL933] gi|3414881|gb|a
aC31492.1| (126アミノ酸のうち100%一致)と同じ; ハイ
ポセティカルタンパク質 例えばHp3 [Escherichia coli
strain CFT073]gi|3661484|gb|aaC61715.1| (74アミノ
酸のうち100%一致)に類似 SEQ ID NO: 69： -0.092042, 290, 新規, L0014 [Esche
richia coli O157:H7 strain EDL933] gi|3288157|emb|
Caa11510.1| (115アミノ酸のうち100%一致)と同じ; ハ
イポセティカルタンパク質 例えばOrf50 [Escherichia
coli strain B171] gi|6009426|dbj|Baa 84885.1| (107
アミノ酸のうち76%一致)に類似 SEQ ID NO: 70： -0.403175, 127, 新規, L0015 [Esche
richia coli O157:H7 strain EDL933] gi|3414883|gb|a
aC31494.1| (512アミノ酸のうち100%一致)と同じ; ハイ
ポセティカルタンパク質 例えば[Escherichia coli プ
ラスミド pColV-K30] gi|3288156|emb|Caa11509.1| (41
1アミノ酸のうち99%一致)に類似 SEQ ID NO: 71： 0.010435, 116, 推定 transposase (i
nterrupted), transposases 例えば[Escherichia coli
strain B171] gi|1004096|gb|aaB36833.1|のN-末端部分
(132アミノ酸のうち89%一致)に類似 SEQ ID NO: 72： -0.445312, 513, 新規, ハイポセティ
カルタンパク質 例えばORF2 in trcA 領域 [Escherichi
a coli strain B171-8] gi|4126790|dbj|Baa36748.1|
(209アミノ酸のうち41%一致); ORF4 in trcA 領域 [Esc
herichia coli strain B171-8] gi|4126792|dbj|Baa367
50.1| (133アミノ酸のうち36%一致)に類似 SEQ ID NO: 73： -0.736428, 141, 新規, ハイポセティ
カルタンパク質 [Lactococcus bacteriophage c2] gi|1
146281|gb|aaA92162.1| (59アミノ酸のうち31%一致)に
類似, GTGスタート SEQ ID NO: 74： -0.321951, 124, 新規 SEQ ID NO: 75： -0.187826, 116, 新規, ハイポセティ
カルタンパク質 例えばORF4 in trcA領域 [Escherichia
coli strain B171-8] gi|4126792|dbj|Baa36750.1| (1
24アミノ酸のうち39%一致); ORF2 in trcA 領域 [Esche
richia coli strain B171-8] gi|4126790|dbj|Baa3674
8.1| (171アミノ酸のうち27%一致)に類似 SEQ ID NO: 76： 0.102083, 49, 新規, ハイポセティカ
ルタンパク質 [Bacteriophage 933W] gi|7649887|dbj|B
aa94165.1| (89アミノ酸のうち93%一致)に類似 SEQ ID NO: 77： -0.173373, 170, 推定 tail fiberタ
ンパク質, tail fiberタンパク質 例えば[Bacteriophag
e 933W] gi|4585436|gb|aaD25464.1|AF125520#59(339ア
ミノ酸のうち34%一致)に類似 SEQ ID NO: 78： -0.320225, 90, 推定 外膜タンパク
質, Lom外膜タンパク質 例えば[Bacteriophage P-EibA]
gi|7532789|gb|aaF63231.1|AF151091#2 (199アミノ酸
のうち68%一致)に類似 SEQ ID NO: 79： -0.644471, 408, probably host spec
ificityタンパク質 (partial), タンパク質 J [Bacteri
ophage lambda] gi|138412|sp|P03749|VHSJ#LAMBDのC-
末端 (77アミノ酸のうち38%一致) に類似, GTGスター
ト, probably disrupted by frameshift SEQ ID NO: 80： -0.313568, 200, host specificityタ
ンパク質 (partial), タンパク質 J [Bacteriophage la
mbda] gi|138412|sp|P03749|VHSJ#LAMBD (639アミノ酸
のうち65%一致)に部分的に類似, probably disrupted b
y frameshift SEQ ID NO: 81： 0.256338, 72, host specificity タ
ンパク質 (interrupted),タンパク質 J [Bacteriophage
lambda] gi|138412|sp|P03749|VHSJ#LAMBDのN-末端部
分 (369アミノ酸のうち80%一致)に類似, truncated by
frameshift SEQ ID NO: 82： -0.181623, 654, tail assembly,tail
assembly タンパク質 例えばGpI [Bacteriophage lamb
da] gi|139637|sp|P03730|VTAI#LAMBD (224アミノ酸の
うち68%一致)に類似 SEQ ID NO: 83： -0.403069, 392, tail assembly, tai
l assembly タンパク質例えばGpK [Bacteriophage lamb
da] gi|139638|sp|P03729|VTAK#LAMBD (196アミノ酸の
うち85%一致) に類似, GTGスタート SEQ ID NO: 84： 0.103097, 227, minor tail componen
t, minor tailタンパク質 例えばGpL [Bacteriophage l
ambda] gi|138844|sp|P03738|VMTL#LAMBD (232アミノ酸
のうち76%一致)に類似 SEQ ID NO: 85： -0.412946, 225, 推定 minor tail co
mponent, minor tailタンパク質 例えばGpM [Bacteriop
hage lambda] gi|138845|sp|P03737|VMTM#LAMBD(110ア
ミノ酸のうち44%一致)に類似, GTGスタート SEQ ID NO: 86： -0.340086, 233, 推定 tail length t
ape measureタンパク質,tail length tape measureタン
パク質 例えば[Bacteriophage HK97] gi|6901589|gb|aa
F31092.1|AF069529#5 (1076アミノ酸のうち52%一致)に
類似 SEQ ID NO: 87： -0.624779, 114, 新規, Gp14 [Bacter
iophage HK97] gi|6901601|gb|aaF31104.1|のC-末端部
分 (96アミノ酸のうち60%一致)に類似, probablyproduc
ed by translational frameshift SEQ ID NO: 88： -0.311204, 1081, 推定 tail assembl
y chaperone, tail assembly chaperone [Bacteriophag
e HK97] gi|6901600|gb|aaF31103.1| (124アミノ酸のう
ち62%一致)に類似 SEQ ID NO: 89： -0.146237, 94, 推定 major tail com
ponent, major tail subunit [Bacteriophage HK97] gi
|6901588|gb|aaF31091.1|AF069529#4 (234アミノ酸のう
ち68%一致)に類似 SEQ ID NO: 90： -0.309678, 125, 新規, Gp11 [Bacter
iophage HK97] gi|6901599|gb|aaF31102.1| (113アミノ
酸のうち49%一致)に類似 SEQ ID NO: 91： -0.186135, 239, 新規, phage ハイポ
セティカルタンパク質 Gp10 [Bacteriophage HK97] gi|
6901598|gb|aaF31101.1| (148アミノ酸のうち75%一致)
に類似 SEQ ID NO: 92： 0.172807, 115, 推定 head-tail adap
tor, 推定 head-tail adaptors 例えば[Bacteriophage
HK97] gi|6901597|gb|aaF31100.1| (111アミノ酸のうち
45%一致)に類似 SEQ ID NO: 93： -0.512838, 149, 新規 SEQ ID NO: 94： -0.192241, 117, 推定 portalタンパ
ク質, portalタンパク質例えば[Bacteriophage D3] gi|
5059250|gb|aaD38955.1| (366アミノ酸のうち24%一致)
に類似 SEQ ID NO: 95： -0.061111, 109, 新規 SEQ ID NO: 96： -0.483469, 860, 推定 major headタ
ンパク質/prohead プロテアーゼ, N-末端部分が推定 pr
ohead プロテアーゼ 例えば[Rhodobacter capsulatus]
gi|6467535|gb|aaF13181.1|AF181080#3 (137アミノ酸の
うち30%一致)に類似; C-末端部分が major head タンパ
ク質 例えば[Mycobacterium phage L5] gi|465114|sp|Q
05223|VG17#BPML5 (280アミノ酸のうち23%一致)に類似 SEQ ID NO: 97： -0.831147, 62, 推定 terminase larg
e subunit, ハイポセティカルタンパク質 例えばphage
D3 terminase-様タンパク質 [Haemophilus influenzae]
gi|6739656|gb|aaF27357.1|AF198256#11 (472アミノ酸
のうち22%一致)に類似 SEQ ID NO: 98： -0.148992, 646, 推定 terminase sma
ll subunit, terminasesmall subunit - PBSX phage Ba
cillus subtilis gi|1722886|sp|P39785|XTMA#BACSU (5
7アミノ酸のうち42%一致)に類似, GTGスタート SEQ ID NO: 99： -0.117179, 554, 新規 SEQ ID NO: 100： -0.648128, 188, 推定 DNase, DNase
[Bacteriophage phi-C31] gi|1107475|emb|Caa62587.1
| (85アミノ酸の28うち%一致) に類似(低い) SEQ ID NO: 101： -1.029787, 48, 新規, ハイポセティ
カルタンパク質 例えば[Escherichia coli] gi|1778472
|gb|aaB40755.1| (67アミノ酸のうち70%一致)に類似 SEQ ID NO: 102： -0.468595, 122, リポタンパク質Rz1
前駆体, リポタンパク質Rz1前駆体 例えば[Bacteriopha
ge933W] gi|4585425|gb|aaD25453.1|AF125520#48 (61ア
ミノ酸のうち98%一致)に類似 SEQ ID NO: 103： -0.717334, 76, endoペプチダーゼ
(cell lysis), Rz [Bacteriophage VT2-Sa] gi|5881639
|dbj|Baa84330.1|と同じ; Rz endoペプチダーゼ例えば
[Bacteriophage lambda] gi|119368|sp|P00726|ENPP#LA
MBD (153アミノ酸のうち69%一致)に類似 SEQ ID NO: 104： 0.214754, 62, 推定 anti-リプレッ
サー, Ant [Bacteriophage 933W] gi|4585423|gb|aaD25
451.1|AF125520#46と同じ; N-末端部分(1-126アミノ酸)
が anti-リプレッサー Ant [Bacteriophage P22] gi|13
1843|sp|P03037|RANT#BPP22 (126アミノ酸のうち49%一
致)に類似 SEQ ID NO: 105： -0.472903, 156, 推定 endolysin, e
ndolysins 例えば[Bacteriophage 933W] gi|4585422|gb
|aaD25450.1|AF125520#45 (177アミノ酸のうち96%一致)
に類似 SEQ ID NO: 106： -0.283069, 190, 新規, ハイポセテ
ィカルタンパク質 YdfR (103アミノ酸) [Escherichia c
oli] gi|3183262|sp|P76160|YDFR#ECOLI (74アミノ酸の
うち45%一致)に類似 SEQ ID NO: 107： -0.466667, 178, 推定 holinタンパ
ク質, holinタンパク質例えば[Bacteriophage H-19B] g
i|2668771|gb|aaD04658.1| (68アミノ酸のうち97%一致)
に類似 SEQ ID NO: 108： -0.074561, 115, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage 933W] (613ア
ミノ酸のうち52%一致)に類似 SEQ ID NO: 109： 0.142647, 69, 新規 SEQ ID NO: 110： -0.212987, 617, 新規 SEQ ID NO: 111： 0.459524, 43, 新規, tellurium res
istanceタンパク質 (TerB) 例えば[Deinococcus radiod
urans] gi|7473690|pir||C75302 (120アミノ酸のうち26
%一致)に類似, TTGスタート SEQ ID NO: 112： -0.452273, 89, 新規, TTGスタート SEQ ID NO: 113： -0.153521, 143, 推定 antiterminat
ion タンパク質, antitermination Q タンパク質 例え
ば[Bacteriophage 82] gi|132277|sp|P13870|RegQ#BP82
(229アミノ酸のうち75%一致)に類似 SEQ ID NO: 114： -0.142593, 55, 推定 crossover jun
ction endodeoxyribonuclease, Gp67 [Bacteriophage H
K97] gi|6901639|gb|aaF31142.1| (114アミノ酸のうち6
4%一致); crossover junction endodeoxyribonucleases
Rus (Hollidayjunction nuclease) (Holliday junctio
n resolvase) [Escherichia coli cryptic lambdoid pr
ophage DLP12] (110アミノ酸のうち40%一致)に類似 SEQ ID NO: 115： -0.425764, 230, B1560#ECOLI gi|17
87843 (348アミノ酸のうち83%一致)に類似, GTGスター
ト SEQ ID NO: 116： -0.304202, 120, 新規 SEQ ID NO: 117： -0.39169, 350, 新規 SEQ ID NO: 118： 0.15098, 52, 新規 SEQ ID NO: 119： 1.332353, 35, 新規, ハイポセティ
カルタンパク質 [Salmonella typhimurium] gi|7467246
|pir||T03012 (69アミノ酸のうち28%一致); Renタンパ
ク質 例えば[Bacteriophage H-19] gi|2668762|gb|aaD0
4649.1| (109アミノ酸のうち26%一致)に類似 SEQ ID NO: 120： -0.410309, 195, 新規, GTGスタート SEQ ID NO: 121： -0.470229, 132, 推定 DNA 複製タン
パク質, DNA複製タンパク質 DnaC homologs 例えば[Esc
herichia coli] gi|7429001|pir||C64886 (246アミノ酸
のうち79%一致)に類似 SEQ ID NO: 122： -0.365766, 223, 推定 複製タンパク
質, C-末端半分が複製タンパク質 例えば[Bacteriophag
e phi-80] gi|137940|sp|P14815|VG15#BPPH8 (148アミ
ノ酸のうち34%一致)に類似; N-末端部分がハイポセティ
カルタンパク質 [Escherichia coli] gi|3025235|sp|P7
5978|YMFN#ECOLI (62アミノ酸のうち68%一致) SEQ ID NO: 123： -0.47439, 247, 新規, ハイポセティ
カルタンパク質 YdaY [Escherichia coli K-12] gi|302
5103|sp|P76064|YDAT#ECOLI (141アミノ酸のうち30%一
致)に類似 SEQ ID NO: 124： -0.667987, 304, 新規, ハイポセテ
ィカルタンパク質 YdaS [Escherichia coli] gi|302510
2|sp|P76063|YDAS#ECOLI (57アミノ酸のうち39%一致)に
類似 SEQ ID NO: 125： -0.42695, 142, 新規, ハイポセティ
カルタンパク質 b1145 [Escherichia coli cryptic pro
phage e14] gi|7444154|pir||F64859 (68アミノ酸のう
ち28%一致)に類似, TTGスタート SEQ ID NO: 126： -0.183, 101, 新規 SEQ ID NO: 127： -0.718055, 145, 新規, ハイポセテ
ィカルタンパク質 例えば[Rhizobium sp. NGR234] gi|2
496690|sp|P55534|Y4KP#RHISN (89アミノ酸のうち38%一
致)に類似 SEQ ID NO: 128： -1.053333, 76, 新規 SEQ ID NO: 129： -0.040217, 93, 新規, GTGスタート SEQ ID NO: 130： -0.648148, 55, 新規, excisionases
例えば[BacteriophageVT2-Sa] dad|AP000363-2|Baa842
85.1| (69アミノ酸のうち43%一致)に類似 SEQ ID NO: 131： -0.001695, 119, 新規 [ハイポセテ
ィカルリポタンパク質],ハイポセティカルタンパク質
例えばCJ0034c [Campylobacter jejuni] gi|6967539|em
b|CAB72527.1 (229アミノ酸のうち35%一致)に類似, GTG
スタート SEQ ID NO: 1595： -0.731325, 84, transposase (inse
rtion sequence IS629),ハイポセティカルタンパク質
例えばTnpE [Shigella flexneri] gi|5532454|gb|aaD44
738.1|AF141323#9 (108アミノ酸のうち99%一致)に類似 SEQ ID NO: 1684： -0.126695, 237, transposase (Orf
B) (insertion sequenceIS629), transposase IS629 gi
|7443863|pir||T00315 (295アミノ酸のうち98%一致)に
類似 SEQ ID NO: 1647： -0.938889, 109, 推定 インテグラ
ーゼ, インテグラーゼ 例えば[Bacteriophage S2] gi|1
679807|emb|Caa96221.1| (331アミノ酸のうち57%一致)
に類似 SEQ ID NO: 1648： -0.432542, 296, 新規, ハイポセテ
ィカルタンパク質 b1839[Escherichia coli] gi|745197
3|pir||G64945 (109アミノ酸のうち33%一致) に類似(低
い) SEQ ID NO: 1158： -0.498198, 334, 新規, cell divis
ion タンパク質 Div [Escherichia coli] gi|2507010|s
p|P15286 (121アミノ酸のうち27%一致) に類似(低い) SEQ ID NO: 1159： -0.102609, 116, 推定 転写調節因
子, 推定 転写調節因子例えば[Neisseria meningitidi
s] gi|7226247|gb|aaF41408.1| (102アミノ酸のうち32%
一致)に類似 SEQ ID NO: 1160： -0.209722, 217, 新規 SEQ ID NO: 1161： -0.639552, 135, 推定 DNA-結合タ
ンパク質, 推定 DNA-bindingタンパク質 Cox [Vibrio c
holerae Bacteriophage K139] gi|4530499|gb|aaD2206
4.1| (56アミノ酸のうち46%一致); phage ハイポセティ
カルタンパク質 例えば[Bacteriophage S2] gi|1679810
|emb|Caa 96224.1| (61アミノ酸のうち42%一致); [Esch
erichia coli retron EC67] gi|141342|sp|P21315|YR7A
#ECOLI (61アミノ酸のうち42%一致)に類似 SEQ ID NO: 1162： -0.051111, 46, 新規 SEQ ID NO: 1163： 0.01194, 68, 新規 SEQ ID NO: 1164： -0.692241, 117, 新規 SEQ ID NO: 1165： -0.229348, 93, 新規 SEQ ID NO: 1166： -0.27625, 81, 新規 SEQ ID NO: 1167： -0.094928, 139, 新規 SEQ ID NO: 1168： -0.673134, 68, 新規 SEQ ID NO: 1169： -0.281818, 89, 新規, ハイポセテ
ィカルタンパク質 例えば[Shigella flexneri] gi|4212
63|pir||S34345 (84アミノ酸のうち41%一致)に類似 SEQ ID NO: 1170： -0.030303, 100, 推定 derepressio
nタンパク質, derepressionタンパク質 epsilon [Bacte
riophage P4] gi|137833|sp|P05463|VEPS#BPP4 (50アミ
ノ酸のうち32%一致) に類似(低い) SEQ ID NO: 1171： -0.201464, 206, 新規 SEQ ID NO: 1172： -0.709211, 77, 推定 複製 タンパ
ク質, 複製タンパク質 例えばGpA [Bacteriophage 186]
gi|1351406|sp|P41064|VPA#BP186 (567アミノ酸のうち
34%一致)に類似 SEQ ID NO: 1173： -0.276033, 122, 推定 プラスミド
partitionの制御, プラスミドpartitionタンパク質 例
えばpar [Escherichia coli プラスミド R1] gi|134954
|sp|P11904|STBA#ECOLI (314アミノ酸のうち46%一致)に
類似 SEQ ID NO: 1174： -0.74575, 895, プラスミド partit
ionの制御, プラスミドpartitionタンパク質 例えばTSB
[Escherichia coli プラスミド NR1] gi|134956|sp|P1
1906|STBB#ECOLI (62アミノ酸のうち40%一致)に類似 SEQ ID NO: 1175： -0.094984, 320, 推定 transposas
e, N-末端部分 (1-103/217アミノ酸)が transposase [E
scherichia coli プラスミド pO157 insertion sequenc
e IS629] gi|7443862|pir||T00240のN-末端部分 (1-103
/296アミノ酸)と同じ, C-末端部分 (104-217/217アミノ
酸)がtransposase [Escherichia coli プラスミド pO15
7 insertion sequence IS629] gi|7443862|pir||T00240
のC-末端部分 (183-296/296アミノ酸)と同じ SEQ ID NO: 1176： -0.466346, 105, transposase, ハ
イポセティカルタンパク質 in insertion sequences 例
えば[Escherichia coli プラスミド pO157 insertion s
equence IS629] gi|7444868|pir||T00241 (108アミノ酸
のうち96%一致)に類似 SEQ ID NO: 1177： -0.368996, 230, 新規, ハイポセテ
ィカルタンパク質 例えばorf20 [Escherichia coli プ
ラスミド pB171] gi|6009396|dbj|Baa84855.1| (158ア
ミノ酸のうち54%一致)に類似 (transferase) SEQ ID NO: 1178： -0.912037, 109, 推定 tailタンパ
ク質, tailタンパク質 例えばF タンパク質 [Bacteriop
hage 186] gi|3337273|gb|aaC34171.1| (151アミノ酸の
うち43%一致)に類似 SEQ ID NO: 1179： -0.174684, 159, 新規, tail タン
パク質 例えばGpT [Bacteriophage P2] gi|3139112|gb|
aaD03293.1|のC-末端部分(66アミノ酸のうち39%一致)に
類似, GTGスタート, probably disrupted by frameshif
t SEQ ID NO: 1180： -0.337037, 163, 推定 tailタンパ
ク質, tail タンパク質例えばGpT [Bacteriophage P2]
gi|3337272|gb|aaC34170.1|のN-末端部分(648アミノ酸
のうち32%一致)に類似, interrupted by frameshift SEQ ID NO: 1181： -0.326978, 279, 推定 phage tail
タンパク質, gi|3139111|gb|aaD03292.1| (42アミノ酸
のうち47%一致)に類似 SEQ ID NO: 1182： -0.055746, 697, 推定 tail タンパ
ク質, tailタンパク質例えばGpE [Bacteriophage P2] g
i|3139110|gb|aaD03291.1| (85アミノ酸のうち31%一致)
に類似 SEQ ID NO: 1183： -0.129487, 79, 推定 tail tube タ
ンパク質, tail tubeタンパク質 例えばtail タンパク
質 FII [Bacteriophage 186] gi|139325|sp|P22502|VPF
2#BPP2 (157アミノ酸のうち44%一致)に類似 SEQ ID NO: 1184： -0.284298, 122, 推定 tail sheath
タンパク質, tail sheathタンパク質 例えばFI [Pseudo
monas aeruginosa bacteriophage phiCTX] gi|4063795|
dbj|Baa36249.1| (377アミノ酸のうち47%一致)に類似 SEQ ID NO: 1185： -0.266471, 171, tail タンパク質,
tail タンパク質 例えばGpD [Bacteriophage P2] gi|6
136287|sp|P10312|VPD#BPP2のN-末端部分(70アミノ酸の
うち59%一致)に類似 SEQ ID NO: 1186： -0.193147, 395, transposase, tra
nsposases 例えば[Escherichia coli insertion sequen
ce IS30] gi|2851554|sp|P37246|TRA8#ECOLI (342アミ
ノ酸のうち99%一致)に類似 SEQ ID NO: 1187： -0.173832, 108, 新規, GTGスター
ト SEQ ID NO: 1188： -0.841108, 344, 新規 SEQ ID NO: 1189： -0.626563, 65, FLIC#ECOLI gi|178
8232 (585アミノ酸のうち55%一致)に類似 SEQ ID NO: 1190： -0.435484, 94, N-末端部分 (1-104
/379アミノ酸)がYEDM#ECOLI gi|1788245 (104アミノ酸
のうち77%一致)に類似, 中心部分 (162-266/379アミノ
酸)がYEDN#ECOLI gi|1788244 (105アミノ酸のうち60%一
致)に類似, C-末端部分 (272-331/379アミノ酸)がにB19
33#ECOLI gi|1788243 (59アミノ酸のうち46%一致) 類
似; YOPM#YERPE SP|P17778 (181アミノ酸のうち27%一
致)に類似(低い)SEQ ID NO: - ： -0.296752, 586, YED
L#ECOLI gi|1788242 のC-末端部分(61-159/159アミノ
酸) (99アミノ酸の93うち%一致)に類似 SEQ ID NO: - ： -0.242216, 380, N-末端部分(1-104/3
79アミノ酸)がYEDM#ECOLI gi|1788245 (104アミノ酸の
うち76%一致)に類似, 中心部分(162-266/379アミノ酸)
がYEDN#ECOLI gi|1788244 (105アミノ酸のうち61%一致)
に類似, C-末端部分(272-331/379アミノ酸)がB1933#ECO
LI gi|1788243 (59アミノ酸のうち53%一致)に類似; IPA
H#SHIFL dad|M32063-1 (146アミノ酸のうち30%一致) に
類似(低い) SEQ ID NO: 1554 -0.263636, 100, 新規, TTGスタート SEQ ID NO: - ： -0.244327, 380, 新規 SEQ ID NO: - ： -0.468966, 117, 推定 secerted effe
ctor タンパク質, ハイポセティカルタンパク質 例えば
EspF [Escherichia coli strain B10] gi|6090818|gb|a
aF03351.1|AF116900#2 ESPF#ECOLI (126アミノ酸のうち
39%一致)に類似 SEQ ID NO: 756： -0.497235, 218, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585437|g
b|aaD25465.1|AF125520#60 (89アミノ酸のうち93%一致)
に類似 SEQ ID NO: 757： -0.686944, 338, 推定 bacteriophag
e tail fiberタンパク質, tail fiber タンパク質 例え
ば[Bacteriophage 933W] gi|4585436|gb|aaD25464.1|AF
125520#59 (370アミノ酸のうち38%一致)に類似 SEQ ID NO: 758： -0.324719, 90, 推定 外膜タンパク
質, Lom 外膜タンパク質前駆体 例えば[prophage P-Eib
A] gi|7532789|gb|aaF63231.1|AF151091#2 (199アミノ
酸のうち68%一致)に類似 SEQ ID NO: 759： -0.67254, 438, bacteriophage host
specificityタンパク質(partial), host specificity
タンパク質 例えばGpJ [Bacteriophage lambda]gi|1384
12|sp|P03749|VHSJ#LAMBD のC-末端部分(788アミノ酸の
58うち%一致)に類似, probably disrupted by frameshi
ft SEQ ID NO: 760： -0.313568, 200, bacteriophage hos
t specificity タンパク質 (interrupted), host speci
ficityタンパク質 例えばタンパク質 J [Bacteriophage
lambda] gi|138412|sp|P03749|のN-末端部分(369アミ
ノ酸のうち80%一致)に類似, GTGスタート, interrupted
by frameshift SEQ ID NO: 761： -0.245668, 809, 推定 tail assembl
y タンパク質, tail assemblyタンパク質 例えばGpI [B
acteriophage lambda] gi|139637|sp|P03730|VTAI#LAMB
D (224アミノ酸のうち69%一致)に類似 SEQ ID NO: 762： -0.365217, 392, bacteriophage ta
il assembly, tail assemblyタンパク質 例えばGpK [Ba
cteriophage lambda] gi|139638|sp|P03729|VTAK#LAMBD
(186アミノ酸のうち87%一致)に類似 SEQ ID NO: 763： 0.086667, 226, possible bacteriop
hage tail component, minor tailタンパク質 例えばGp
L [Bacteriophage lambda] gi|138844|sp|P03738|VMTL#
LAMBD (232アミノ酸のうち76%一致)に類似 SEQ ID NO: 764： -0.344973, 190, bacteriophage tai
l component, minor tailタンパク質 例えばGpM [Bacte
riophage lambda] gi|138845|sp|P03737|VMTM#LAMBD (1
09アミノ酸のうち79%一致)に類似 SEQ ID NO: 765： -0.3125, 233, tail length determi
nation, tail length tape measureタンパク質前駆体
例えばGpH [Bacteriophage lambda] gi|138843|sp|P037
36|VMTH#LAMBDのC-末端部分(253アミノ酸のうち80%一
致)に類似, probablydisrupted by frameshift SEQ ID NO: 766： -0.43945, 110, bacteriophage tail
length determination,tail length tape measure タ
ンパク質 例えばGpH [Bacteriophage lambda] gi|13884
3|sp|P03736|VMTH#LAMBDのN-末端部分(587アミノ酸のう
ち76%一致) に類似, interrupted by frameshift SEQ ID NO: 767： -0.258268, 255, bacteriophage tai
l component, minor tailタンパク質 例えばGpT [Bacte
riophage lambda] gi|138846|sp|P03735|VMTT#LAMBD (9
6アミノ酸のうち78%一致)に類似, probably produced b
y translationalframeshift SEQ ID NO: 768： -0.505, 621, bacteriophage tail c
omponent, minor tailタンパク質 例えばGpG [Bacterio
phage lambda]gi|138842|sp|P03734|VMTG#LAMBD(167ア
ミノ酸のうち68%一致)に類似 SEQ ID NO: 769： 0.034653, 102, 新規 SEQ ID NO: 770： -0.22028, 144, bacteriophage head
component, major headタンパク質 例えばGp7 [Bacter
iophage 21] gi|547612|sp|P36270|HEAD#BPP21percent
gi|547612|sp|P36270|のN-末端部分 (88アミノ酸のうち
95%一致)に類似, probably interrupted SEQ ID NO: 771： -0.239801, 202, bacteriophage hea
d component, head decorationタンパク質 例えばGpshp
[Bacteriophage 21] gi|549437|sp|P36275|VSHP#BPP21
(115アミノ酸のうち95%一致)に類似 SEQ ID NO: 772： -0.331818, 89, bacteriophage head
-tail preconnector, minor headタンパク質 例えばhea
d-tail preconnector Gp5 [Bacteriophage 21] gi|5492
96|sp|P36273|VG05#BPP21 (501アミノ酸のうち97%一致)
に類似, scaffoldタンパク質(302-501アミノ酸) - homo
log of Gp6 [Bacteriophage 21]を含む SEQ ID NO: 773： -0.024348, 116, bactreiophage por
talタンパク質, portalタンパク質 例えばGp5 [Bacteri
ophage 21] gi|549295|sp|P36272|VG04#BPP21 (530アミ
ノ酸のうち98%一致)に類似 SEQ ID NO: 774： 0.055688, 502, 推定 head completi
on タンパク質, phageタンパク質 例えばhead completi
on タンパク質 Gp3 [Bacteriophage 21] gi|549294|sp|
P36271|VG03#BPP21 (68アミノ酸のうち98%一致)に類似 SEQ ID NO: 775： -0.448868, 531, bacteriophage ter
minase large subunit,terminase large subunits 例え
ばGp2 [Bacteriophage 21] gi|2851579|sp|P36693|TERL
#BPP21 (637アミノ酸のうち91%一致)に類似 SEQ ID NO: 776： -0.394118, 69, possible bacteriop
hage terminase small subunit, terminase small subu
nits 例えばGp1 [Bacteriophage N15] gi|7444578|pir|
|T13087 (106アミノ酸のうち42%一致)に類似, GTGスタ
ート SEQ ID NO: 777： -0.425233, 643, 転写調節因子, Per
C (BfpW) [Escherichiacoli] gi|1172431|sp|P43475|PE
RC#ECOLI (87アミノ酸のうち47%一致)に類似 SEQ ID NO: 778： -0.508875, 170, リポタンパク質前
駆体, リポタンパク質Rz1前駆体 例えば[Bacteriophage
933W] gi|4585425|gb|aaD25453.1|AF125520#48 (61ア
ミノ酸のうち85%一致)に類似 SEQ ID NO: 779： -0.983654, 105, endoペプチダーゼ
(host cell lysis), Rzendoペプチダーゼ 例えば[Bacte
riophage VT2-Sa] gi|5881639|dbj|Baa84330.1|(154ア
ミノ酸のうち83%一致)に類似 SEQ ID NO: 780： 0.178689, 62, 新規 SEQ ID NO: 781： -0.26, 156, possible endolysin,
例えばR タンパク質 [Bacteriophage H-19B] gi|433568
6|gb|aaD17382.1| (177アミノ酸のうち98%一致)に類似 SEQ ID NO: 782： 0.62, 61, 新規, YdfR [Escherichia
coli] gi|3183262|sp|P76160|YDFR#ECOLI (74アミノ酸
のうち44%一致)に類似 SEQ ID NO: 783： -0.393785, 178, possible holinタ
ンパク質 (host cell lysis), holinタンパク質 例えば
タンパク質 [Bacteriophage VT2-Sa] gi|5881636|dbj|B
aa84327.1| (68アミノ酸のうち94%一致)に類似 SEQ ID NO: 784： -0.114912, 115, transposase, ハイ
ポセティカルタンパク質[Escherichia coli プラスミド
pO157 insertion sequence IS629] gi|7444868|pir||T
00241と同じ SEQ ID NO: 785： 0.133823, 69, transposase, transp
osase [Escherichia coli プラスミド pO157 insertion
sequence IS629] gi|7443862|pir||T00240と同じ SEQ ID NO: 786： -0.965741, 109, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage 933W] gi|458
5419|gb|aaD25447.1|AF125520#42 (613アミノ酸のうち5
3%一致)に類似 SEQ ID NO: 787： -0.397973, 297, 新規, GTGスタート SEQ ID NO: 788： -0.243181, 617, 新規, GTGスタート SEQ ID NO: 789： 0.475926, 55, 新規, 推定 TerBタン
パク質 例えば[Deinococcus radiodurans] gi|7473690|
pir||C75302 (120アミノ酸のうち26%一致)に類似 SEQ ID NO: 790： 1.385455, 56, antitermination, an
titerminators 例えばタンパク質 Q [Bacteriophage 8
2] gi|132277|sp|P13870|R例えばQ#BP82 (229アミノ酸
のうち75%一致)に類似 SEQ ID NO: 791： -0.143662, 143, crossover junctio
n endodeoxyribonuclease, Rusタンパク質 例えば[Bact
eriophage 82] gi|6901639|gb|aaF31142.1| GP67#BPHK9
7 (112アミノ酸のうち63%一致)に類似; Gp67 [Bacterio
phage HK97] gi|6901639|gb|aaF31142.1| (112アミノ酸
のうち63%一致)に類似 SEQ ID NO: 792： -0.393886, 230, 新規, ハイポセテ
ィカルタンパク質 例えばb1560 [Escherichia coli] gi
|7466196|pir||C64911 (348アミノ酸のうち85%一致)に
類似, GTGスタート SEQ ID NO: 793： -0.221009, 120, 新規, orf QD1 [Ba
cteriophage N15] gi|2564084|gb|aaB81659.1| (64アミ
ノ酸のうち31%一致)に類似 SEQ ID NO: 794： -0.35702, 350, prophage maintenan
ce (modulation of hostcell killing), Hok/Gef famil
y 例えばMokW [Bacteriophage 933W] gi|4585453|gb|aa
D25481.1|AF125520#76 (70アミノ酸のうち87%一致)に類
似 SEQ ID NO: 795： -1.208696, 93, 新規 SEQ ID NO: 796： 0.081429, 71, 新規, N-末端部分(1-
46アミノ酸)が GP45 [Bacteriophage N15] gi|7521552|
pir||T13131 (46アミノ酸のうち56%一致)に類似;N-末端
部分(37-97アミノ酸)がb2363 [Escherichia coli] gi|7
451977|pir||H65009 (61アミノ酸のうち73%一致)に類似 SEQ ID NO: 797： 1.402941, 35, 新規 SEQ ID NO: 798： -0.425134, 188, 新規, GTGスタート SEQ ID NO: 799： -0.893204, 104, 新規 SEQ ID NO: 800： -1.069355, 63, 新規 SEQ ID NO: 801： -0.171186, 119, 新規, YdaW [Esche
richia coli] gi|3025105|sp|P76066|YDAW#ECOLI (135
アミノ酸のうち61%一致)に類似 SEQ ID NO: 802： -0.148649, 75, 推定 ファージ複製
タンパク質, 複製タンパク質 例えばGp14 [Bacteriopha
ge phi-80] gi|137937|sp|P14814|VG14#BPPH8 (129アミ
ノ酸のうち47%一致)に類似 SEQ ID NO: 803： -0.504741, 233, 新規, 複製termina
tion factor dnaT (primosomal タンパク質 I) [Escher
ichia coli] gi|1361001|pir||S56589 (85アミノ酸のう
ち30%一致)に類似 SEQ ID NO: 804： -0.721364, 221, 新規, YdaT [Esche
richia coli] gi|3025103|sp|P76064|YDAT#ECOLI (83ア
ミノ酸のうち31%一致)に類似; 調節タンパク質 CII [Ba
cteriophage phi-80] gi|133360|sp|P14820|RPC2#BPPH8
(40アミノ酸のうち40%一致) に類似(低い) SEQ ID NO: 805： -0.660869, 346, 推定 cell divisio
n controlタンパク質 (リプレッサー), DicC (リプレッ
サー タンパク質 of division inhibition genedicB)
[Escherichia coli] gi|118633|sp|P06965|DICC#ECOLI
(72アミノ酸のうち31%一致)に類似 SEQ ID NO: 806： -0.360284, 142, possible リプレッ
サータンパク質, リプレッサータンパク質 例えばC2 リ
プレッサー [Bacteriophage P22] gi|133359|sp|P03035
|RPC2#BPP22 (203アミノ酸のうち30%一致)に類似 SEQ ID NO: 807： -0.694667, 76, 新規 SEQ ID NO: 808： -0.046047, 216, possible cell div
ision inhibitor, DicBタンパク質 [Escherichia coli]
gi|2507009|sp|P09557|DICB#ECOLI (55アミノ酸のうち
65%一致)に類似 SEQ ID NO: 809： -0.494, 51, 新規, ハイポセティカ
ルタンパク質 例えばYdfD[Escherichia coli] gi|14058
7|sp|P29010|YDFD#ECOLI (62アミノ酸のうち46%一致)に
類似 SEQ ID NO: 810： -0.01129, 63, 新規 SEQ ID NO: 811： 0.119355, 63, 新規 SEQ ID NO: 812： -0.751913, 733, 新規 SEQ ID NO: 813 ： -0.487736, 107, インテグラーゼ,
インテグラーゼ 例えば[Bacteriophage HK022] gi|138
560|sp|P16407|VINT#BPHK0 (316アミノ酸のうち24%一
致)に類似 SEQ ID NO: 814： -0.347761, 68, 新規, ハイポセティ
カルタンパク質 例えばL0013 [Escherichia coli O157:
H7 strain EDL933] gi|3414881|gb|aaC31492.1|(133ア
ミノ酸のうち100%一致)に類似, GTGスタート SEQ ID NO: 815： -0.722352, 341, 新規, ハイポセテ
ィカルタンパク質 例えばL0014 [Escherichia coli O15
7:H7 strain EDL933] gi|3288157|emb|Caa11510.1| (11
5アミノ酸のうち100%一致)に類似 SEQ ID NO: 1581： -0.388722, 134, 新規, ハイポセテ
ィカルタンパク質 例えばL0015 [Escherichia coli O15
7:H7 strain EDL933] gi|3414883|gb|aaC31494.1| (512
アミノ酸のうち100%一致)に類似 SEQ ID NO: 1582： 0.010435, 116, 新規 SEQ ID NO: 1583： -0.445312, 513, transposase (ins
ertion sequence IS629), IS629 ハイポセティカルタン
パク質 例えば[Escherichia coli プラスミド pO157] g
i|7444868|pir||T00241 (108アミノ酸のうち96%一致)に
類似 SEQ ID NO: 1349： -0.262963, 55, transposase (inse
rtion sequence IS629),IS629 transposase [Escherich
ia coli プラスミド pO157) gi|7443862|pir||T00240
(296アミノ酸のうち96%一致)に類似 SEQ ID NO: 1350： -0.942593, 109, 新規, ハイポセテ
ィカルタンパク質 例えばYjdA [Escherichia coli] gi|
731985|sp|P16694|YJDA#ECOLI (236アミノ酸のうち17%
一致)に部分的に に類似(低い) SEQ ID NO: 1351： -0.402027, 297, 新規, ハイポセテ
ィカルタンパク質 YjcZ[Escherichia coli] gi|731984|
sp|P39267|YJCZ#ECOLI (278アミノ酸のうち29%一致)に
類似, GTGスタート SEQ ID NO: 1352： -0.652559, 294, 新規, ハイポセテ
ィカルタンパク質 例えば[Xanthomonas campestris] gi
|6689533|emb|CAB65709.1| (74アミノ酸のうち44%一致)
に類似(低い) SEQ ID NO: 1353： -0.372093, 302, 新規 SEQ ID NO: 1354： 0.036798, 357, 新規 SEQ ID NO: 1355： -0.067841, 228, 新規, ハイポセテ
ィカルタンパク質 例えばYafZ [Escherichia coli] gi|
2495487|sp|P77206|YAFZ#ECOLI (272アミノ酸のうち75%
一致)に類似 SEQ ID NO: 1356： -0.074265, 137, 推定 antirestric
tion タンパク質, ハイポセティカルタンパク質 例えば
YfjX [Escherichia coli] gi|1723636|sp|P52139|YFJX#
ECOLI (152アミノ酸のうち68%一致); に類似 antirestr
ictionタンパク質 例えばKlcA タンパク質 [プラスミド
RK2] gi|1730051|sp|P52603|KLA2#ECOLI (139アミノ酸
のうち38%一致)に類似 SEQ ID NO: 1357： -0.550183, 274, acetyltransferas
e, WbdR [Escherichia coli O157:H7 C664-1992] gi|34
35182|gb|aaC32350.1|と同じ SEQ ID NO: 1358： -0.385535, 160, 新規, H repeat-a
ssociated タンパク質例えば[Escherichia coli] gi|14
0772|sp|P28912|YHHI#ECOLIのC-末端部分 (36アミノ酸
のうち66%一致)に類似, TTGスタート SEQ ID NO: 1259： 0.180543, 222, 新規, H repeat-as
sociated タンパク質 例えば[Escherichia coli] gi|14
0772|sp|P28912|YHHI#ECOLI (49アミノ酸のうち75%一
致)に類似 SEQ ID NO: 1260： 0.204, 51, 新規, H repeat-associ
ated タンパク質 例えば[Escherichia coli] gi|140772
|sp|P28912|YHHI#ECOLI (36アミノ酸のうち83%一致)に
類似, GTGスタート SEQ ID NO: 1261： -0.351852, 55, phosphomannomutas
e, ManB [Escherichia coli O157:H7 C664-1992] gi|34
35181|gb|aaC32349.1|と同じ SEQ ID NO: 1262： -0.141667, 37, mannose-1-P guano
syltransferase, ManC [Escherichia coli O157:H7 C66
4-1992] gi|3435180|gb|aaC32348.1|と同じ SEQ ID NO: 1263： -0.222368, 457, probabl例えばDP-
L-fucose pathway enzyme, WbdQ [Escherichia coli O1
57:H7 C664-1992] gi|3435179|gb|aaC32347.1|と同じ SEQ ID NO: 1264： -0.221577, 483, fucose synthetas
e, Fcl [Escherichia coli O157:H7 C664-1992] gi|486
7922|dbj|Baa77731.1|と同じ SEQ ID NO: 1265： -0.168047, 170, GDP-D-mannose de
hydratase, Gmd [Escherichia coli O157:H7 C664-199
2]gi|3435177|gb|aaC32345.1|と同じ SEQ ID NO: 1266： -0.264486, 322, 例えばlycosyl tr
ansferase, WbdP [Escherichia coli O157:H7 C664-199
2] gi|3435176|gb|aaC32344.1|に類似 SEQ ID NO: 1267： -0.261021, 373, perosamine synth
etase, Per [Escherichia coli O157:H7 C664-1992] gi
|3435175|gb|aaC32343.1|と同じ SEQ ID NO: 1268： -0.176485, 405, O antigen flippa
se, Wzx [Escherichia coli O157:H7 C664-1992] gi|34
35174|gb|aaC32342.1|と同じ SEQ ID NO: 1269： -0.321585, 367, probabl例えばlyc
osyl transferase, WbdO[Escherichia coli O157:H7 C6
64-1992] gi|3435173|gb|aaC32341.1|と同じ SEQ ID NO: 1270： 0.75141, 462, O antigen polymera
se, Wzy [Escherichia coli O157:H7 C664-1992] gi|34
35172|gb|aaC32340.1|と同じ, GTGスタート SEQ ID NO: 1271： -0.16371, 249, 例えばlycosyl tra
nsferase, WbdN [Escherichia coli O157:H7 C664-199
2] gi|4867915|dbj|Baa77724.1|と同じ SEQ ID NO: 1272： 0.558884, 395, 推定 UDP-galactos
e 4-epimerase, 推定 UDP-galactose 4-epimerase [Vib
rio cholerae] gi|3724321|dbj|Baa33610.1 (329アミノ
酸のうち27%一致)に類似 SEQ ID NO: 1273： -0.404615, 261, 新規, ハイポセテ
ィカルタンパク質 例えばgi|9106618|gb|aaF84382.1|AE
003986#12 [Xylella fastidiosa] (105アミノ酸のうち6
0%一致)に類似 SEQ ID NO: 1638： -0.29577, 332, 新規, ハイポセテ
ィカルタンパク質 [Xylella fastidiosa] gb|aaF84486.
1|AE003993#5 (86アミノ酸のうち52%一致)に類似 SEQ ID NO: 1692： -0.842857, 113, 新規 SEQ ID NO: 1693： -0.109375, 97, 新規 SEQ ID NO: 1588： -0.478481, 80, 新規 [推定 外膜
タンパク質; OMP] SEQ ID NO: 1589： -0.057391, 116, YEHA#ECOLI gi|17
88426 (207アミノ酸のうち44%一致)に類似 [推定 type-
1 fimbrial タンパク質] SEQ ID NO: 1590： 0.006731, 105, に類似 YEHB#ECOLI
gi|1788427 (826アミノ酸のうち92%一致); usher タン
パク質 MrkC [Klebsiella pneumoniae] dad|M55912-4|a
aA25095.1 (810アミノ酸のうち32%一致)に類似 SEQ ID NO: - ： -0.098256, 345, に類似 YEHC#ECOLI
gi|1788428 (224アミノ酸のうち87%一致); chaperone M
rkB [Klebsiella pneumoniae] dad|M55912-3|aaA25094.
1 (211アミノ酸のうち39%一致)に類似 SEQ ID NO: - ： -0.513075, 827, YEHD#ECOLI gi|1788
429 (180アミノ酸のうち85%一致); AC/I pili タンパク
質 [Escherichia coli] dad|X76121-1|Caa53727.1 (177
アミノ酸のうち28%一致)に類似 SEQ ID NO: - ： -0.266071, 225, YEHE#ECOLI gi17884
30 (93アミノ酸のうち69%一致)に類似 SEQ ID NO: - ： 0.199444, 181, 推定 molybdate 代謝
調節因子, molybdate 代謝調節因子 MolR [Escherichia
coli] gi|7466653|pir||B64979のN-末端部分(1-244/12
64アミノ酸) (249アミノ酸のうち37%一致)に類似, GTG
スタート SEQ ID NO: - ： -0.272043, 94, 推定 molybdate 代謝
調節因子, molybdate代謝調節因子 molR [Escherichia
coli] gi|465576|sp|P33345|MOLR#ECOLIのC-末端部分
(1000アミノ酸のうち45%一致)に類似, GTGスタート SEQ ID NO: - ： -0.647107, 243, transposase (OrfB)
(insertion sequence IS629), gi|7443862|pir||T0024
0と同じ SEQ ID NO: 1509： -0.306124, 948, transposase (Orf
A) (insertion sequenceIS629), gi|7444868|pir||T002
41 (108アミノ酸のうち99%一致)に類似 SEQ ID NO: 1650： -0.397973, 297, 新規 SEQ ID NO: 1651： -0.958333, 109, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage 933W] gi|458
5437|gb|aaD25465.1|AF125520#60 (102アミノ酸のうち9
7%一致)に類似, TTGスタート SEQ ID NO: 555： -0.584146, 83, 推定 tail fiber タ
ンパク質, tail fiberタンパク質 例えば[Bacteriophag
e 933W] gi|4585436|gb|aaD25464.1|AF125520#59 (361
アミノ酸のうち36%一致)に類似 SEQ ID NO: 556： -0.411765, 103, 推定 外膜タンパク
質 Lom前駆体, Lom前駆体 例えば[Bacteriophage P-Eib
A] gi|7532789|gb|aaF63231.1|AF151091#2 (199アミノ
酸のうち76%一致)に類似 SEQ ID NO: 557： -0.679634, 438, 推定 host specifi
city タンパク質 (partial), host specificタンパク質
例えばGpJ [Bacteriophage lambda] gi|138412|sp|P03
749|VHSJ#LAMBDのC-末端(775アミノ酸のうち62%一致)に
類似, GTGスタート SEQ ID NO: 558： -0.288442, 200, 推定 host specifi
cタンパク質 (interrupted), host specificityタンパ
ク質 例えばGpJ [Bacteriophage lambda] gi|138412|sp
|P03749|VHSJ#LAMBDのN-末端 (369アミノ酸のうち80%
一致)に類似, GTGスタート, probably truncated by fr
amesift SEQ ID NO: 559： -0.197032, 776, 推定 tail assembl
yタンパク質, tail assemblyタンパク質 例えばGpI [Ba
cteriophage lambda] gi|139637|sp|P03730|VTAI#LAMBD
(224アミノ酸のうち69%一致)に類似 SEQ ID NO: 560： -0.365217, 392, 推定 tail assembl
y タンパク質, tail assembly タンパク質 例えばGpK
[Bacteriophage lambda] gi|139638|sp|P03729|VTAK#LA
MBD (196アミノ酸のうち86%一致)に類似 SEQ ID NO: 561： 0.086667, 226, 推定 minor tail タ
ンパク質, minor tailタンパク質 例えばGpI[Bacteriop
hage lambda] gi|138844|sp|P03738|VMTL#LAMBD (232ア
ミノ酸のうち76%一致)に類似 SEQ ID NO: 562： -0.32996, 248, 推定 minor tailタ
ンパク質, minor tail タンパク質 例えばGpM [Bacteri
ophage lambda] gi|138845|sp|P03737|VMTM#LAMBD(109
アミノ酸のうち79%一致)に類似 SEQ ID NO: 563： -0.3125, 233, 推定 tail length ta
pe measureタンパク質前駆体, tail length tape measu
reタンパク質前駆体 例えばGpH [Bacteriophagelambda]
gi|138843|sp|P03736|VMTH#LAMBD (876アミノ酸のうち
49%一致)に類似 SEQ ID NO: 564： -0.43945, 110, 推定 minor tail タ
ンパク質, minor tailタンパク質 例えばGpT [Bacterio
phage lambda] gi|138846|sp|P03735|VMTT#LAMBD(102ア
ミノ酸のうち70%一致)に類似, probably produced by t
ranslational frameshift SEQ ID NO: 565： -0.353916, 882, 推定 minor tailタ
ンパク質, minor tailタンパク質 例えばGpG [Bacterio
phage lambda] gi|138842|sp|P03734|VMTG#LAMBD (140
アミノ酸のうち43%一致)に類似 SEQ ID NO: 566： -0.358824, 103, 新規 SEQ ID NO: 567： -0.545714, 141, 推定 minor tail
タンパク質 U, minor tail タンパク質 例えばGpU [Bac
teriophage lambda] gi|138847|sp|P03732|VMTU#LAMBD
(132アミノ酸のうち55%一致)に類似 SEQ ID NO: 568： -0.34, 251, 推定 minor tail タン
パク質, minor tail タンパク質 例えばGpZ [Bacteriop
hage lambda] gi|138849|sp|P03731|VMTZ#LAMBD (206ア
ミノ酸のうち52%一致)に類似 SEQ ID NO: 569： -0.141667, 133, 新規 SEQ ID NO: 570： -0.45942, 208, 新規 (ハイポセティ
カル膜タンパク質) SEQ ID NO: 571： -0.103226, 94, 新規 SEQ ID NO: 572： 0.549074, 109, transposase (OrfA)
(insertion sequence IS629), ハイポセティカルタン
パク質 [Escherichia coli プラスミド pO157 insertio
n sequence IS629] gi|7444868|pir||T00241と同じ SEQ ID NO: 573： -0.202367, 339, transposase (Orf
B) (insertion sequenceIS629), transposase [Escheri
chia coli プラスミド pO157 insertion sequence IS62
9] gi|7443862|pir||T00240と同じ SEQ ID NO: 574： -0.958333, 109, 推定 プロテアーゼ
/scaffold タンパク質,ClpP プロテアーゼ 例えば[Bact
eriophage D3] gi|5059251|gb|aaD38956.1| (195アミノ
酸のうち39%一致); 推定 scaffolding タンパク質 [Str
eptococcus thermophilus bacteriophage DT1] gi|4530
143|gb|aaD21883.1| (193アミノ酸のうち31%一致)に類
似, GTGスタート SEQ ID NO: 575： -0.397973, 297, 推定 portal タン
パク質, portalタンパク質-様タンパク質 [Wolbachia s
p. wKue] gi|6723246|dbj|Baa89642.1| (438アミノ酸の
うち24%一致)に類似; portal タンパク質 例えばgp4 [p
hage 21] gi|549295|sp|P36272|VG04#BPP21 (368アミノ
酸のうち20%一致)に類似(低い) SEQ ID NO: 576： -0.101359, 369, 新規 SEQ ID NO: 577： -0.4932, 501, 推定 terminase larg
e subunit, terminase large subunit-様 タンパク質
[Wolbachia sp. wKue] gi|6723244|dbj|Baa89640.1| (6
29アミノ酸のうち25%一致); terminase large subunits
例えばGpA [Bacteriophage lambda] gi|137616|sp|P03
708|TERL#LAMBD (615アミノ酸のうち23%一致)に類似, G
TGスタート SEQ ID NO: 578： -0.598718, 79, 新規 SEQ ID NO: 579： -0.665488, 708, リポタンパク質 Rz
1前駆体, リポタンパク質Rz1前駆体 例えば[Bacterioph
age 933W] gi|4585425|gb|aaD25453.1|AF125520#48 (61
アミノ酸のうち98%一致)に類似 SEQ ID NO: 580： -0.458861, 159, endoペプチダーゼ
(host cell lysis), Rz[Bacteriophage VT2-Sa] gi|588
1639|dbj|Baa84330.1|と同じ; endoペプチダーゼ 例え
ばRz [Bacteriophage lambda] gi|119368|sp|P00726|EN
PP#LAMBD (153アミノ酸のうち69%一致)に類似 SEQ ID NO: 581： 0.214754, 62, 推定 antiリプレッサ
ー タンパク質, 推定 antiリプレッサー タンパク質 [B
acteriophage 933W] gi|4585423|gb|aaD25451.1|AF1255
20#46と同じ; N-末端部分(1-126アミノ酸)がantiリプレ
ッサータンパク質Ant [Bacteriophage P22] (126アミノ
酸のうち49%一致)に類似 SEQ ID NO: 582： -0.472903, 156, 推定 endolysin, e
ndolysin [Bacteriophage 933W] gi|4585422|gb|aaD254
50.1|AF125520#45と同じ; endolysins 例えばRタンパ
ク質 [Bacteriophage H-19B] gi|4335686|gb|aaD17382.
1| (177アミノ酸のうち93%一致)に類似 SEQ ID NO: 583： -0.283069, 190, 推定 holin タンパ
ク質, 推定 holin [Bacteriophage 933W] gi|4499808|e
mb|CAB39307.1|と同じ; holin タンパク質 例えばタン
パク質 [Bacteriophage 21] gi|138706|sp|P27360|VLYS
#BPP21 (71アミノ酸のうち77%一致)に類似 SEQ ID NO: 584： -0.449153, 178, 新規, ハイポセテ
ィカルタンパク質 例えば[Shigella dysenteriae] gi|6
759966|gb|aaF28124.1|AF153317#20 (81アミノ酸のうち
91%一致)に類似 SEQ ID NO: 585： 0.039437, 72, 新規, ハイポセティ
カルタンパク質 [Bacteriophage 933W] gi|4499806|emb
|CAB39305.1|と同じ SEQ ID NO: 586： -0.312346, 82, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage VT2-Sa] gi|588
1634|dbj|Baa84325.1| (649のうち92%一致)に類似 SEQ ID NO: 587： 0.008475, 60, Shiga toxin I subun
it B前駆体, Shiga toxin I subunit B前駆体 gi|13453
9|sp|P08027|SLTB#BPH30と同じ SEQ ID NO: 588： -0.218518, 649, Shiga toxin I sub
unit A前駆体, Shiga toxin I subunit A前駆体 [Shige
lla dysenteriae] gi|134537|sp|P10149|SLTA#BPH30と
同じ SEQ ID NO: 589： 0.031461, 90, antitermination タ
ンパク質, antiterminationタンパク質 例えばタンパク
質 Q [Bacteriophage H-19B] (144アミノ酸のうち95%一
致)に類似 SEQ ID NO: 590： 0.083492, 316, 新規, ハイポセティ
カルタンパク質 例えばNin 68 [Bacteriophage lambda]
gi|1351593|sp|P03771|Y68#LAMBD (60アミノ酸のうち8
0%一致)に類似 SEQ ID NO: 591： -0.268056, 145, 新規, ハイポセテ
ィカルタンパク質 例えばNinG タンパク質 [Bacterioph
age 21] gi|4539482|emb|CAB39991.1| (201アミノ酸の
うち90%一致)に類似 SEQ ID NO: 592： -0.534375, 65, 新規, ハイポセティ
カルタンパク質 例えばNinF [Bacteriophage P22] gi|5
12350|emb|Caa55162.1| (58アミノ酸のうち96%一致)に
類似 SEQ ID NO: 593： -1.045273, 202, 新規 SEQ ID NO: 594： -0.286957, 70, 新規, ハイポセティ
カルタンパク質 [Bacteriophage VT2-Sa] gi|5881625|d
bj|Baa84316.1|と同じ; Nin Eタンパク質 例えば[Bacte
riophage 21] (57アミノ酸のうち100%一致)に類似 SEQ ID NO: 595： -0.939098, 134, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage VT2-Sa] gi|5
881624|dbj|Baa84315.1| (175のうち98%一致); DNA N-6
-adenine-methyltransferase [Bacteriophage T1] (143
アミノ酸のうち31%一致)に類似 SEQ ID NO: 596： -1.339655, 59, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage 933W] gi|45854
10|gb|aaD25438.1|AF125520#33 (148アミノ酸のうち98%
一致); Nin B [Bacteriophage 21] gi|4539479|emb|CAB
39988.1| (147アミノ酸のうち43%一致)に類似 SEQ ID NO: 597： -0.174286, 176, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage SEQ ID NO: 9
33W] gi|4585409|gb|aaD25437.1|AF125520#32 (109アミ
ノ酸のうち99%一致)に類似, GTGスタート SEQ ID NO: 598： -0.739189, 149, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage 933W] gi|449
9788|emb|CAB39287.1| (92アミノ酸のうち97%一致)に類
似 SEQ ID NO: 599： 0.00851, 142, Ren タンパク質, Ren
タンパク質 例えば[Bacteriophage lambda] gi|139473
|sp|P03761|VREN#LAMBD (96アミノ酸のうち97%一致)に
類似 SEQ ID NO: 600： -0.872826, 93, ファージ複製 タン
パク質 P, ファージ複製タンパク質 P 例えば[Bacterio
phage lambda] gi|139488|sp|P03689|VRPP#LAMBD(233ア
ミノ酸のうち97%一致)に類似 SEQ ID NO: 601： -0.0375, 97, ファージ複製タンパク
質 O, ファージ複製タンパク質 O 例えば[Bacteriophag
e 933W] gi|4585405|gb|aaD25433.1|AF125520#28(312ア
ミノ酸のうち99%一致)に類似 SEQ ID NO: 602： -0.448927, 234, 調節 タンパク質 C
II, 調節 タンパク質 CII 例えば[Bacteriophage 933W]
gi|4585404|gb|aaD25432.1|AF125520#27 (98アミノ酸
のうち94%一致)に類似 SEQ ID NO: 603： -0.815064, 313, 推定 調節タンパク
質, 推定 調節タンパク質 例えば[Bacteriophage VT2-S
a] gi|5881616|dbj|Baa84307.1| (71アミノ酸のうち42%
一致)に類似 SEQ ID NO: 604： -0.220408, 99, 推定 prophage リプ
レッサー CI, prophageリプレッサー CI 例えば[Bacter
iophage lambda] gi|133353|sp|P03034|RPC1#LAMBD (20
5アミノ酸のうち48%一致)に類似 SEQ ID NO: 605： -0.223611, 73, 新規 SEQ ID NO: 606： -0.193868, 213, 新規 (ハイポセテ
ィカル膜タンパク質) SEQ ID NO: 607： -0.194624, 94, 推定 調節 タンパク
質 (転写 anti-termination), 推定 転写anti-terminat
ionタンパク質 例えばタンパク質 N [Bacteriophage ph
i-21] gi|132274|sp|P07243|R例えばN#BPPH3 (64アミノ
酸のうち99%一致)に類似 SEQ ID NO: 608： -0.036066, 184, 新規 SEQ ID NO: 609： -0.355556, 91, 推定 superinfectio
n exclusion タンパク質, superinfection exclusion
タンパク質 B [Bacteriophage P22] gi|585991|sp|P383
96|SIEB#BPP22 (191アミノ酸のうち84%一致)に類似 SEQ ID NO: 610： 0.358824, 52, 推定 single-strande
d DNA結合タンパク質,推定 single-stranded DNA結合タ
ンパク質 [Bacteriophage 933W] と同じ; Ea10(single-
stranded DNA結合タンパク質) [Bacteriophage lambda]
gi|137630|sp|P03757|VE10#LAMBD (122アミノ酸のうち
99%一致)に類似 SEQ ID NO: 611： -0.012435, 194, 調節 タンパク質 c
III (antitermination),調節タンパク質cIII [Bacterio
phage lambda] gi|133366|sp|P03044|RPC3#LAMBD と同
じ SEQ ID NO: 612： -0.263935, 123, Kil タンパク質 (h
ost killing), Kilタンパク質 例えば[Bacteriophage l
ambda] gi|138622|sp|P03758|VKIL#LAMBD (89アミノ酸
のうち97%一致)に類似 SEQ ID NO: 613： -0.544444, 55, host-nuclease inhi
bitor タンパク質 Gam (interrupted), gam [Bacteriop
hage lambda] のN-末端部分(37アミノ酸のうち99%一致)
に類似 SEQ ID NO: 614： -0.120225, 90, 推定 host-nuclease
inhibitor タンパク質Gam, Gam [Bacteriophage lambd
a] gi|138128|sp|P03702|VGAM#LAMBD のC-末端部分(98
アミノ酸のうち99%一致)に類似, probably disrupted b
y frameshift SEQ ID NO: 615： -0.28, 51, recombination タンパク
質 Bet, Bet タンパク質[Bacteriophage 933W] gi|4585
391|gb|aaD25419.1|AF125520#14と同じ; Bet タンパク
質 [Bacteriophage lambda] gi|137511|sp|P03698|VBET
#LAMBD (261アミノ酸のうち99%一致)に類似 SEQ ID NO: 616： -0.707143, 99, exonuclease, exonu
cleases [Bacteriophage933W] gi|4585390|gb|aaD2541
8.1|AF125520#13と同じ; exonucleases 例えば[Bacter
iophage lambda] gi|119702|sp|P03697|EXO#LAMBD (225
アミノ酸のうち97%一致)に類似 SEQ ID NO: 617： -0.509195, 262, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585389|g
b|aaD25417.1|AF125520#12と同じ; ハイポセティカルタ
ンパク質 orf60a [Bacteriophage lambda] gi|508995|g
b|aaA96568.1| (62アミノ酸のうち95%一致)に類似 SEQ ID NO: 618： -0.358667, 226, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585388|g
b|aaD25416.1|AF125520#11と同じ; orf63 [Bacteriopha
ge lambda] gi|508994|gb|aaA96567.1| (61アミノ酸の
うち88%一致)に類似 SEQ ID NO: 619： -0.13871, 63, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage 933W] gi|45853
87|gb|aaD25415.1|AF125520#10と同じ; ハイポセティカ
ルタンパク質 orf61 [Bacteriophage lambda] (46アミ
ノ酸のうち93%一致)に類似 SEQ ID NO: 620： -0.192064, 64, 推定 C4-type zinc
fingerタンパク質 (TraRfamily), 推定 C4-type zinc f
ingerタンパク質 (TraR family) 例えばgi|7649830|dbj
|Baa94108.1| (73アミノ酸のうち93%一致)に類似 621： -0.410753, 94, 新規, N-末端部分がハイポセテ
ィカルタンパク質 例えば[Bacteriophage 933W] gi|458
5455|gb|aaD25483.1|AF125520#78 (168アミノ酸のうち6
8%一致)に類似; C-末端部分が ハイポセティカルタンパ
ク質 [Bacteriophage HK022] gi|6863138|gb|aaF30379.
1|AF069308#27 (196アミノ酸のうち96%一致)に類似, GT
Gスタート SEQ ID NO: 622： -0.617808, 74, 新規 SEQ ID NO: 623： -0.622222, 316, 新規, N-末端部分
(1-44アミノ酸)が ハイポセティカルタンパク質 例えば
[Bacteriophage 933W] gi|4585382|gb|aaD25410.1|AF12
5520#5 (44アミノ酸のうち84%一致)に類似 SEQ ID NO: 624： -0.068966, 59, 新規, ハイポセティ
カルタンパク質 例えば[Bacteriophage 933W] gi|45854
55|gb|aaD25483.1|AF125520#78 (90アミノ酸のうち41%
一致)に部分的に類似 SEQ ID NO: 625： -0.482204, 119, 新規 SEQ ID NO: 626： -0.8125, 121, 推定 excisionase,
推定 excisionases 例えば[Bacteriophage 933W] gi|45
85379|gb|aaD25407.1|AF125520#2 (74アミノ酸のうち47
%一致)に類似 SEQ ID NO: 627： -0.72, 81, 推定 インテグラーゼ,
インテグラーゼ 例えば[Bacteriophage 933W] gi|45853
78|gb|aaD25406.1|AF125520#1 (423アミノ酸のうち65%
一致)に類似 SEQ ID NO: 628： -0.803572, 85, 推定 salicylate hy
droxylase, salicylatehydroxylases 例えば[Streptomy
ces coelicolor] gi|7481300|pir||T36193 (348アミノ
酸のうち31%一致)に類似 SEQ ID NO: 629： -0.471028, 429, probabl例えばluta
thione-S-transferase,glutathione-S-transferases 例
えば[Pseudomonas sp. U2] gi|3406829|gb|aaC29501.1|
(210アミノ酸のうち43%一致)に類似 SEQ ID NO: 1444： -0.21864, 398, 推定 isomerase, i
somerase 例えばisomerase-decarboxylase homolog [Ps
eudomonas sp. U2] gi|3406828|gb|aaC29500.1|(188ア
ミノ酸のうち46%一致); に類似 ハイポセティカルタン
パク質 Orf2 [Sphingomonas sp. RW5] gi|3550668|emb|
Caa12268.1| (228アミノ酸のうち54%一致)に類似 SEQ ID NO: 1445： 0.236279, 216, probabl例えばenti
sate 1,2-dioxygenase,gentisate 1,2-dioxygenases 例
えば[Pseudomonas alcaligenes] gi|5733104|gb|aaD494
27.1|AF173167#1 (333アミノ酸のうち53%一致); [Sphin
gomonas sp. RW5] gi|3550667|emb|Caa12267.1| (339ア
ミノ酸のうち45%一致)に類似 SEQ ID NO: 1446： -0.183691, 234, 推定 輸送タンパ
ク質, 輸送タンパク質 例えば4-hydroxybenzoate トラ
ンスポーター [Pseudomonas putida] gi|6093655|sp|Q5
1955|PCAK#PSEPU (420アミノ酸のうち42%一致)に類似 SEQ ID NO: 1447： -0.411988, 343, 推定 調節タンパ
ク質, 調節タンパク質 例えばgalactose 結合タンパク
質調節因子 [Azospirillum brasilense] gi|1730232|sp
|P52661|GBPR#AZOBR (281アミノ酸のうち32%一致)に類
似 SEQ ID NO: 1448： 0.803097, 453, 推定 antibiotic r
esistanceタンパク質, antibiotic resistance タンパ
ク質 homolog YwoG [Bacillus subtilis] gi|7474437|p
ir||B70065 (381アミノ酸のうち38%一致)に類似 SEQ ID NO: 1449： -0.049371, 319, 推定 転写調節因
子, 推定 転写調節因子例えばYvbU [Bacillus subtili
s] gi|6648030|sp|O32255 (266アミノ酸のうち32%一致)
に類似 SEQ ID NO: - ： 0.973737, 397, 新規 SEQ ID NO: - ： 0.093836, 293, transposase (OrfA)
(insertion sequence IS629), ハイポセティカルタンパ
ク質 gi|7444868|pir||T00241 SEQ ID NO: 1623, ECs3123:3078013-3079083; -0.67247
2, 357, transposase (OrfB) (insertion sequence IS6
29) と同じ, gi|7443862|pir||T00240 SEQ ID NO: 1653： -0.965741, 109, B2332#ECOLI gi|7
466328|pir||B65006 (289アミノ酸のうち41%一致)に類
似 SEQ ID NO: 1654： -0.397973, 297, B2333#ECOLI gi17
88674 (174アミノ酸のうち56%一致); minor fimbrial s
ubunit StfG タンパク質 [Salmonella typhimurium] da
d|AF093503-7|aaC64157.1 (139アミノ酸のうち48%一致)
に類似 SEQ ID NO: 1572： -0.075, 281, に類似 B2334#ECOLI
gi|1788675 (141アミノ酸のうち53%一致); minor fimbr
ial subunits 例えばStfF [Salmonella typhimuｒｉｕ
ｍ］ ｇｉ３７４７０３３ （１５８アミノ酸のうち53
%一致)に類似 SEQ ID NO: 1573： 0.123626, 183, に類似 B2335#ECOL
I gi|1788676 (166アミノ酸のうち47%一致); minor fim
brial subunit StfE タンパク質 [Salmonella typhimur
ium] dad|AF093503-5|aaC64155.1 (154アミノ酸のうち4
8%一致)に類似 SEQ ID NO: 1574： -0.085256, 157, YFCS#ECOLI gi|17
88677 (250アミノ酸のうち85%一致); periplasmic fimb
rial chaperone StfD タンパク質 [Salmonella typhimu
rium] dad|AF093503-4|aaC64154.1 (233アミノ酸のうち
59%一致)に類似 SEQ ID NO: 1575： 0.534337, 167, N-末端部分(1-581/
883アミノ酸)がYFCU#ECOLI gi|1788679 (577アミノ酸の
うち90%一致)に類似, C-末端部分(587-883/883アミノ
酸)がB2337#ECOLI gi|1788678 (297アミノ酸のうち88%
一致)に類似 SEQ ID NO: -： -0.305159, 253, B2339#ECOLI gi|1788
680 (187アミノ酸のうち88%一致); major fimbrial sub
unit StfA タンパク質 [Salmonella typhimurium] dad|
AF093503-2|aaC64152.1 (187アミノ酸のうち39%一致)に
類似 SEQ ID NO: - ： -0.461661, 880, 推定 DNA injection
タンパク質, N-末端部分がDNA injectionタンパク質 g
p20 [phage P22] gi|1174950|sp|Q01076|VG20#BPP22のN
-末端部分(217アミノ酸のうち47%一致) に類似; C-末端
部分がハイポセティカルタンパク質 例えば[Caenorhabd
itis el例えばans] gi|5805382|gb|aaD51972.1|AF17337
2#1のC-末端部分 (76アミノ酸のうち34%一致) に類似
(低い) SEQ ID NO: - ： -0.20107, 188, 推定 DNA transferタ
ンパク質前駆体, DNA transferタンパク質 Gp7 [Bacter
iophage P22] gi|418222|sp|Q01074|VG07#BPP22(207ア
ミノ酸のうち66%一致)に類似 SEQ ID NO: 1289： -0.056085, 379, 新規, ハイポセテ
ィカルタンパク質 P31 [Bacteriophage APSE-1] gi|611
8026|gb|aaF03974.1|AF157835#31 (152アミノ酸のうち3
5%一致); gp14 [Bacteriophage P22] gi|418225|sp|Q01
075|VG14#BPP22(143アミノ酸のうち22%一致)に類似 SEQ ID NO: 1290： -0.180088, 227, 新規 SEQ ID NO: 1291： -0.107742, 156, 推定 複製 タンパ
ク質, 複製 タンパク質例えば[Haemophilus actinomyce
temcomitans プラスミド pVT736-1] gi|398106|gb|aaC3
7125.1| (145アミノ酸のうち26%一致)に部分的に類似 SEQ ID NO: 1292： 0.176842, 96, 新規 SEQ ID NO: 1293： -0.803463, 232, 新規 SEQ ID NO: 1294： -1.430769, 53, 新規 SEQ ID NO: 1295： -0.364681, 471, 推定 resolvase,
resolvases 例えば[プラスミド pM3] gi|5668998|gb|aa
D46124.1|AF078924#3 (204アミノ酸のうち46%一致); [Y
ersinia pestis プラスミドpMT1] gi|7467461|pir||T14
990 (193アミノ酸のうち43%一致)に類似 SEQ ID NO: 1296： -0.218966, 59, sucrose 輸送 タン
パク質, sucrose 輸送タンパク質 (permease) [Escheri
chia coli strain EC3132] gi|231914|sp|P30000|CSCB#
ECOLI (415アミノ酸のうち99%一致)に類似 SEQ ID NO: 1297： -0.367308, 209, 推定 fructoキナ
ーゼ, fructoキナーゼ (EC 2.7.1.4) 例えば[Escherich
ia coli strain EC3132] gi|730731|sp|P40713|SCRK#EC
OLI (291アミノ酸のうち98%一致)に類似 SEQ ID NO: 1298： 0.823615, 416, sucrose hydrolas
e, sucrose hydrolase [Escherichia coli strain EC31
32] gi|3462879|gb|aaC33123.1| (477アミノ酸のうち98
%一致)に類似 SEQ ID NO: 1299： 0.010855, 305, sucrose operon リ
プレッサー, sucrose operon リプレッサー [Escherich
ia coli] SEQ ID NO: gi|729214|sp|P40715|CSCR#ECOLI
(331アミノ酸のうち99%一致)に類似 SEQ ID NO: 1300： -0.532914, 478, に類似 EryA homo
logue [Bacteriophage If1] dad|U02303-9|aaC62159.1
(333アミノ酸のうち76%一致) SEQ ID NO: 1301： -0.041088, 332, 推定 transposas
e, transposase homologA [Helicobacter pylori] gi|2
114470|gb|aaD11513.1 (137アミノ酸のうち58%一致)に
類似 SEQ ID NO: 1618： -0.604712, 383, FLXA#ECOLI gi|24
98386|sp|P77609 (74アミノ酸のうち43%一致)に類似 SEQ ID NO: - ： -0.437222, 181, 推定 polyferredoxi
n, ferredoxin [Methanosarcina thermophila] gi|2826
43|pir||A42960 (43アミノ酸のうち48%一致); に類似 p
olyferredoxin [Methanococcus voltae] gi|99156|pir|
|S24802 (207アミノ酸のうち22%一致)に類似 SEQ ID NO: - ： -0.478761, 114, 推定 anaerobic dim
ethyl sulfoxide reductase chain C, anaerobic dimet
hyl sulfoxide reductase chain C 例えば[Escherichia
coli] gi|118699|sp|P18777|DMSC#ECOLI (271アミノ酸
のうち27%一致)に類似 SEQ ID NO: 1490： -0.1, 285, 推定 anaerobic dimeth
yl sulfoxide reductasechain B, anaerobic dimethyl
sulfoxide reductases chain B 例えば[Escherichia c
oli] gi|2506394|sp|P18776|DMSB#ECOLI (185アミノ酸
のうち59%一致)に類似 SEQ ID NO: 1491： 1.152381, 274, 推定 anaerobic di
methyl sulfoxide reductase chain A前駆体, anaerobi
c dimethyl sulfoxide reductase chain A前駆体例えば
[Escherichia coli] gi|118697|sp|P18775|DMSA#ECOLI
(768アミノ酸のうち43%一致)類似に SEQ ID NO: 1492： -0.325837, 210, 新規, DNA damage
-inducible タンパク質例えばDinI [Escherichia coli]
gi|2498305|sp|Q47143|DINI#ECOLI (81アミノ酸のうち
43%一致)に類似 SEQ ID NO: 1493： -0.412988, 794, 新規, 推定 Cys3H
is zinc finger タンパク質 ATCTH [Arabidopsis thali
ana] gi|1800279|gb|aaB68046.1| (35アミノ酸のうち37
%一致) に類似(低い) SEQ ID NO: 1061： -0.60122, 83, chaperone-様 タン
パク質, TrcA-様 タンパク質 例えばbfpT-r例えばulate
d chaperone-様 タンパク質 TrcA [Escherichiacoli st
rain B171-8] gi|4126789|dbj|Baa36747.1| (195アミノ
酸のうち85%一致)に類似 SEQ ID NO: 1062： -0.528302, 54, 新規, ハイポセテ
ィカルタンパク質 例えばORF2 [Escherichia coli stra
in B171-8] gi|4126790|dbj|Baa36748.1| (216アミノ酸
のうち99%一致)に類似 SEQ ID NO: 1063： -0.526531, 197, 新規, ハイポセテ
ィカルタンパク質 ORF3[Escherichia coli strain B171
-8] gi|4126791|dbj|Baa36749.1| (352アミノ酸のうち9
8%一致)に類似 SEQ ID NO: 1064： -0.181019, 217, 新規, ハイポセテ
ィカルタンパク質 例えばORF4 [Escherichia coli stra
in B171-8] gi|4126792|dbj|Baa36750.1| (140アミノ酸
のうち99%一致)に類似 SEQ ID NO: 1065： -0.571307, 353, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4585437|g
b|aaD25465.1|AF125520#60 (129アミノ酸のうち93%一
致)に類似 SEQ ID NO: 1066： -0.416429, 141, transposase, ハ
イポセティカルタンパク質 [Escherichia coli プラス
ミド pO157 insertion sequence IS629] gi|7444868|pi
r||T00241と同じ; ハイポセティカルタンパク質, IS el
ements 例えばTnpE[Shigella flexneri] gi|5532454|gb
|aaD44738.1|AF141323#9 (108アミノ酸のうち97%一致)
に類似 SEQ ID NO: 1067： -0.251938, 130, transposase, tra
nsposase [Escherichiacoli プラスミド pO157 inserti
on sequence IS629] gi|7443862|pir||T00240と同じ SEQ ID NO: 1068： -0.965741, 109, 新規, N-末端部分
(1-87アミノ酸)がハイポセティカルタンパク質 例えばL
0015 (50-136/512アミノ酸) [Escherichia coliO157:H7
strain EDL933] gi|3414883|gb|aaC31494.1|に部分的
に類似 SEQ ID NO: 1069： -0.397973, 297, 新規, ハイポセテ
ィカルタンパク質 L0014[Escherichia coli O157:H7 st
rain EDL933] gi|3288157|emb|Caa11510.1|と同じ; ハ
イポセティカルタンパク質 例えばORF50 [Escherichia
coli] gi|6009426|dbj|Baa84885.1| (107アミノ酸のう
ち76%一致)に類似 SEQ ID NO: 1070： -0.501818, 166, 新規, ハイポセテ
ィカルタンパク質 例えばL0013 [Escherichia coli O15
7:H7 strain EDL933] gi|3414881|gb|aaC31492.1| (126
アミノ酸のうち100%一致)に類似 SEQ ID NO: 1071： 0.010435, 116, 推定 endolysin (h
ost cell lysis), endolysins 例えば[Bacteriophage 9
33W] gi|4585422|gb|aaD25450.1|AF125520#45のN-末端
半分 (73アミノ酸のうち93%一致)に類似, probably int
errupted SEQ ID NO: 1072： -0.403175, 127, 新規, ハイポセテ
ィカルタンパク質 YdfR[Escherichia coli] gi|3183262
|sp|P76160|YDFR#ECOLI (74アミノ酸のうち47%一致)に
類似 SEQ ID NO: 1073： -0.144737, 77, holin (host cell
lysis), holinタンパク質 例えば[Bacteriophage VT2-S
a] gi|5881636|dbj|Baa84327.1| (91アミノ酸のうち90%
一致)に類似 SEQ ID NO: 1074： -0.027193, 115, 新規, ハイポセテ
ィカルタンパク質 例えば[Bacteriophage 933W] gi|458
5419|gb|aaD25447.1|AF125520#42 (613アミノ酸のうち5
2%一致)に類似 SEQ ID NO: 1075： 0.095775, 72, 新規 SEQ ID NO: 1076： -0.210048, 618, 新規, ハイポセテ
ィカルタンパク質 例えば[Actinobacillus actinomycet
emcomitans] gi|7592819|dbj|Baa94406.1 (228アミノ酸
のうち29%一致)に類似 SEQ ID NO: 1077： 0.446789, 110, anititermination,
antiterminationタンパク質 例えばタンパク質 Q [Bac
teriophage lambda] gi|132278|sp|P03047|R例えばQ#LA
MBD (207アミノ酸のうち97%一致)に類似 SEQ ID NO: 1078： 0.628745, 248, serine/threonine
タンパク質 phosphatase,serine/threonineタンパク質p
hosphatases 例えば[Bacteriophage lambda] gi|130792
|sp|P03772|PP#LAMBD (221アミノ酸のうち95%一致)に類
似 SEQ ID NO: 1079： -0.263768, 208, 新規, ハイポセテ
ィカルタンパク質 例えばNinG [Bacteriophage 21] gi|
4539482|emb|CAB39991.1| (199アミノ酸のうち89%一致)
に類似 SEQ ID NO: 1080： -0.243891, 222, 新規, phage ハイ
ポセティカルタンパク質例えば[Bacteriophage phi-YeO
3-12] gi|6598993|emb|CAB63597.1| (110アミノ酸のう
ち32%一致)に類似 SEQ ID NO: 1081： -1.078325, 204, 推定 transposas
e, transposases 例えば[Escherichia coli insertion
sequence IS30] gi|2851554|sp|P37246|TRA8#ECOLIのN-
末端部分(247アミノ酸のうち100%一致)に類似 SEQ ID NO: 1082： -0.772872, 189, 新規, TTGスター
ト SEQ ID NO: 1083： -0.849402, 252, 新規 SEQ ID NO: 1084： -0.28168, 132, 新規ＳＥＱ ＩＤ
ＮＯ： １０８５： -1.133413, 423, 新規 SEQ ID NO: 1086： -0.535766, 138, 新規, C-末端部分
が ctp synthase - Rickettsia prowasekii gi|7438005
|pir||C71695 (138アミノ酸のうち24%一致)に類似; N-
末端部分がハイポセティカルタンパク質 - Plasmodium
falciparum gi|4493974|emb|CAB39033.1| (129アミノ酸
のうち24%一致)に類似 SEQ ID NO: 1087： -0.442424, 133, 新規 SEQ ID NO: 1088： -0.501657, 544, 推定 インテグラ
ーゼ, site specific recombinases 例えばインテグラ
ーゼ-recombinaseタンパク質 [Methanobacterium therm
oautotrophicum] gi|7428936|pir||D69219 (174アミノ
酸のうち27%一致)に類似 SEQ ID NO: 1089： -0.314416, 438, 新規 (DNA結合 タ
ンパク質), 推定 DNA-結合タンパク質 [Bacteriophage
P4] gi|140147|sp|P12552|Y9K#BPP4 (50アミノ酸のうち
42%一致); に類似 ハイポセティカルタンパク質 例えば
[Yersinia pestis] gi|7467337|pir||T17447 (40アミノ
酸のうち46%一致)に類似 SEQ ID NO: 1090： -0.426185, 402, 新規 SEQ ID NO: 1091： -0.441176, 69, 推定 調節因子, 調
節タンパク質 例えばMocR [Sinorhizobium meliloti] g
i|1346565|sp|P49309 (466アミノ酸のうち34%一致)に類
似 SEQ ID NO: 1092： -0.333569, 284, 新規, conserved
ハイポセティカルタンパク質 [Streptomyces coelicolo
r A3(2)] gi|7649565|emb|CAB89054.1 (141アミノ酸の
うち38%一致)に類似 SEQ ID NO: 1597： -0.168469, 445, 新規, ハイポセテ
ィカルタンパク質 例えばVdcD [Streptomyces sp. D7]
gi|4741970|gb|aaD28783.1|AF134589#3のN-末端部分
(71アミノ酸のうち57%一致); YclD [Bacillus subtili
s] gi|7452267|pir||A69762 (68アミノ酸のうち48%一
致)に類似 SEQ ID NO: 1598： -0.074126, 144, 推定 4-hydroxybe
nzoate decarboxylase,YclC [Escherichia coli O157:H
7 strain?] gi|4887556|emb|CAB43499.1| (475アミノ酸
のうち100%一致)と同じ; VdcC [Streptomyces sp. D7]
gi|6686069|sp|Q9X697|VDCC#STRD7 (474アミノ酸のうち
72%一致); 4-hydroxybenzoate decarboxylase [Clostri
dium hydroxybenzoicum] gi|5739200|gb|aaD50377.1|AF
128880#1(469アミノ酸のうち53%一致)に類似 SEQ ID NO: 1541： -0.65, 79, 推定 phenylacrylic ac
id decarboxylase, Pad1[Escherichia coli O157:H7 st
rain ?] gi|4887557|emb|CAB43500.1|と同じ; phenylac
rylic acid decarboxylases 例えばVdcB [Streptomyces
sp. D7] (190アミノ酸のうち73%一致)に類似 SEQ ID NO: 1542： -0.214105, 476, 転写調節因子, Sl
yA [Escherichia coli O157:H7 strain ?] to gi|48875
58|emb|CAB43501.1|と同じ;転写 調節因子s 例えば[Str
eptomyces coelicolor] gi|7481485|pir||T35022 (124
アミノ酸のうち32%一致)に類似 SEQ ID NO: 1543： 0.027919, 198, 新規, ハイポセテ
ィカルタンパク質 例えば[Escherichia coli] gi|74044
94|sp|P45956|YGBF#ECOLI (94アミノ酸のうち86%一致)
に類似 SEQ ID NO: 1544： -0.374074, 136, 新規, ハイポセテ
ィカルタンパク質 b2755[Escherichia coli strain K-1
2] gi|7460139|pir||G65056 (303アミノ酸のうち84%一
致)に類似, GTGスタート SEQ ID NO: 1330： 0.025773, 98, 新規, ハイポセティ
カルタンパク質 b2756 [Escherichia coli strain K-1
2] gi|6136707|sp|Q46897|YGCH#ECOLI (200アミノ酸の
うち28%一致) に類似(低い) SEQ ID NO: 1331： -0.038111, 308, 新規, ハイポセテ
ィカルタンパク質 b2757[Escherichia coli strain K-1
2] gi|7459357|pir||A65057 (160アミノ酸のうち35%一
致)に類似 SEQ ID NO: 1332： -0.411111, 217, 新規, ハイポセテ
ィカルタンパク質 b2758[Escherichia coli strain K-1
2] gi|7476186|pir||C70849 (93アミノ酸のうち32%一
致)に類似

【００２２】５）調節因子配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 1333： -0.537097, 249, 新規 SEQ ID NO: 1334： -0.248718, 352, 新規, ハイポセテ
ィカルタンパク質 b2760[Escherichia coli strain K-1
2] gi|7451979|pir||D65057 (303アミノ酸のうち24%一
致)に類似 SEQ ID NO: 1335： -0.612921, 179, 新規, ハイポセテ
ィカルタンパク質 YgcB[Escherichia coli strain K-1
2] gi|2506493|sp|P38036|YGCB#ECOLI (778アミノ酸の
うち28%一致)に類似, GTGスタート SEQ ID NO: 1336： -0.429615, 521, YBDY#ECOLI gi|30
25009|sp|P77091 (50アミノ酸のうち78%一致); に類似
SrnB [プラスミド F] dad|AP001918-5|Baa97875.1 (49
アミノ酸のうち42%一致)に類似 SEQ ID NO: 1337： -0.257627, 886, 新規, ハイポセテ
ィカルタンパク質 例えばTp70 [Treponema pallidum] g
i|7521576|pir||A71309 (124アミノ酸のうち35%一致)に
類似 SEQ ID NO: - ： 0.81, 51, 新規, ハイポセティカルタ
ンパク質 例えばYgcG [Escherichia coli] gi|1723817|
sp|P55140|YGCG#ECOLIのN-末端部分(186アミノ酸のうち
43%一致)に類似 SEQ ID NO: 1512： -0.608397, 132, 新規 SEQ ID NO: 1513： 0.301786, 225, 新規, N-末端部分
が ハイポセティカルタンパク質 例えばYgcG [Escheric
hia coli] gi|1723817|sp|P55140|YGCG#ECOLIのN-末端
部分 (147アミノ酸のうち31%一致)に類似 SEQ ID NO: 1514： 0.238, 51, に類似 YGCG#ECOLI gi|
1789140 (275アミノ酸のうち40%一致); ハイポセティカ
ルタンパク質 [Pseudomonas aeruginosa] dad|AE004490
-5|aaG03925.1 (273アミノ酸のうち43%一致)に類似, GT
Gスタート SEQ ID NO: 1515： 0.225393, 383, リポタンパク質前
駆体 (type III secretion system), type III secreti
on systemのリポタンパク質前駆体 例えばPrgK タンパ
ク質 [Salmonella typhimurium] gi|1172615|sp|P41786
|PRGK#SALTY (231アミノ酸のうち53%一致)に類似 SEQ ID NO: - ： 0.151648, 274, type III secretion
タンパク質, MxiI [Shigella flexneri] gi|547954|sp|
Q06080|MXII#SHIFL (93アミノ酸のうち32%一致);PrgJ
タンパク質 [Salmonella typhimurium] gi|1172614|sp|
P41785|PRGJ#SALTＹ （８７アミノ酸のうち31%一致)に
類似 SEQ ID NO: 1192： 0.037705, 245, type III secretio
nタンパク質, 推定 typeIII secretionタンパク質 例え
ばPrgI タンパク質 [Salmonella typhimurium]gi|11726
13|sp|P41784|PRGI#SALTY (76アミノ酸のうち64%一致)
に類似 SEQ ID NO: 1193： -0.282727, 111, 推定 adherence f
actor, adherence factors 例えばEfa1 [Escherichia c
oli O111:H- strain E45035] gi|6013469|gb|aaD49229.
2|AF159462#1の一部(433-711/3223アミノ酸) (279アミ
ノ酸のうち100%一致)に類似, probably disrupted by f
rameshift SEQ ID NO: 1194： -0.588608, 80, transposase, tran
sposase [Escherichia coli プラスミドpO157 IS629] g
i|7443862|pir||T00240と同じ SEQ ID NO: 1195： -0.379918, 245, transposase, ハ
イポセティカルタンパク質 [Escherichia coli プラス
ミドpO157 IS629] gi|7444868|pir||T00241と同じ; ハ
イポセティカルタンパク質, insertion sequences 例え
ば[Shigella flexneri] gi|5532454|gb|aaD44738.1|AF1
41323#9 (108アミノ酸のうち96%一致)に類似 SEQ ID NO: 1196： -0.045181, 167, 新規, GTGスター
ト SEQ ID NO: 1197： -0.081233, 374, 新規, ハイポセテ
ィカルタンパク質 例えばL0014 [Escherichia coli O15
7:H7 strain EDL933] gi|3414882|gb|aaC31493.1| (115
アミノ酸のうち99%一致)に類似 SEQ ID NO: 1198： 1.038462, 79, 新規, ハイポセティ
カルタンパク質 例えばL0015 [Escherichia coli O157:
H7 strain EDL933] gi|3414883|gb|aaC31494.1|(411ア
ミノ酸のうち100%一致)に類似 SEQ ID NO: 1199： 0.805162, 151, 新規, ハイポセテ
ィカルタンパク質 例えばL0013 [Escherichia coli O15
7:H7 strain EDL933] gi|3414881|gb|aaC31492.1|の部
分 (28アミノ酸のうち55%一致)に類似, GTGスタート, p
robably disrupted SEQ ID NO: 1200： 0.976744, 87, 新規, ハイポセティ
カルタンパク質 例えばORF50 [Escherichia coli プラ
スミド pB171] gi|6009426|dbj|Baa84885.1| (106アミ
ノ酸のうち70%一致)に類似 SEQ ID NO: 1201： 0.748416, 222, 新規, ハイポセテ
ィカルタンパク質 例えばL0015 [Escherichia coli O15
7:H7 strain EDL933] gi|3414883|gb|aaC31494.1|(464
アミノ酸のうち63%一致)に類似 SEQ ID NO: 1202： -0.236585, 329, 新規, transposas
es 例えばTnpA [Shigella flexneri] gi|5532449|gb|aa
D44733.1|AF141323#4の部分(49アミノ酸のうち93%一致)
に類似 SEQ ID NO: 1203： -1.506341, 206, 新規, ハイポセテ
ィカルタンパク質 例えばL0004 [Escherichia coli O15
7:H7 strain EDL933] gi|3414872|gb|aaC31483.1| (91
アミノ酸のうち98%一致); 推定 transposase [Vibrio c
holerae] gi|7960026|gb|aaF71186.1|AF179596#6 (91ア
ミノ酸のうち59%一致); ハイポセティカルタンパク質
[Escherichia coli プラスミドpO157 insertion sequen
ce IS911] gi|7465897|pir||T00224 (91アミノ酸のうち
52%一致)に類似 SEQ ID NO: 1204： -0.892208, 78, 推定 転写調節因
子, 調節因子 (RpiR family) 例えば[Bacillus subtili
s] gi|8248807|emb|CAB93068.1| (236アミノ酸のうち25
%一致)に類似 SEQ ID NO: 1205： -1.002703, 112, 推定 ferrichrome
-結合タンパク質, ferrichrome-結合タンパク質 例えば
[Bacillus subtilis] gi|585132|sp|P37580|FHUD#BACSU
(220アミノ酸のうち%27一致)に類似 SEQ ID NO: 1206： -0.212558, 440, 推定 ferrichrome
ABCトランスポーター (permease), ferrichrome ABCト
ランスポーター(permease) 例えば[Bacillus subtilis]
gi|1706797|sp|P49937|FHUG#BACSU (319アミノ酸のう
ち33%一致)に類似 SEQ ID NO: 1207： 0.465452, 687, 推定 ferrichrome
ABCトランスポーター (permease), ferrichrome ABCト
ランスポーター (permease) 例えば[Synechocystis s
p.] gi|7442493|pir||S74438 (315アミノ酸のうち43%一
致); [Bacillus subtilis] gi|1706795|sp|P49936|FHUB
#BACSU (319アミノ酸のうち39%一致)に類似 SEQ ID NO: 1208： -0.209449, 382, 推定 ABC-type ir
on-siderophore輸送系ATP-結合タンパク質, ABC-type i
ron-siderophore 輸送系ATP-結合タンパク質 例えば[Sy
nechocystis sp.] gi|7442509|pir||S74440 (248アミノ
酸のうち52%一致)に類似 SEQ ID NO: 1209： -0.149383, 568, 推定 ferrichrome
-iron レセプター前駆体, ferrichrome-ironレセプター
前駆体 例えばgi|7448497|pir||S74457 (688アミノ酸の
うち30%一致)に類似 SEQ ID NO: 1210： 0.036546, 250, 新規, TTGスタート SEQ ID NO: 1211： 1.166101, 60, PTS依存性N-acetyl-
galactosamine-IID component (AgaE), PTS依存性N-ace
tyl-galactosamine-IID component, AgaE [Escherichia
coli strain C] gi|8895749|gb|aaF81085.1|AF228498#
5 (292アミノ酸のうち96%一致)に類似 SEQ ID NO: - ： -0.257895, 77, PTS 依存性 N-acetyl
-galactosamine-およびgalactosamine IIA component
(AfaF), ts 依存性 N-acetyl-galactosamine-およびgal
actosamine IIA component, AgaF [Escherichia coli s
train C] gi|8895750|gb|aaF81086.1|AF228498#6 (144
アミノ酸のうち99%一致)に類似 SEQ ID NO: 1527： 0.06993, 144, transposase (inser
tion sequence IS629),ハイポセティカルタンパク質 gi
|7444868|pir||T00241と同じ SEQ ID NO: 1528： 1.167709, 193, transposase (inse
rtion sequence IS629),gi|7443862|pir||T00240と同じ SEQ ID NO: 1529： 0.38766, 236, 新規 SEQ ID NO: 1530： -0.008, 226, leader ペプチダー
ゼ, leader ペプチダーゼ例えばHopD (strain ECOR30)
[Escherichia coli] gi|7674073|sp|O68932 (155アミノ
酸のうち92%一致); (LT2) [Salmonella typhimurium] g
i|7674072|sp|O68927 (148アミノ酸のうち68%一致)に類
似 SEQ ID NO: 1531： -0.168, 226, 新規, ハイポセティ
カルタンパク質 [Xylellafastidiosa] gi|9112262|gb|a
aF85593.1|AE003851#24 (86アミノ酸のうち50%一致)に
類似 SEQ ID NO: - ： -0.265401, 238, 推定 invasin, 推定
膜タンパク質 b1978 [Escherichia coli K-12] gi|173
6642|dbj|Baa15799.1| (1391アミノ酸のうち45%一致);
vasin [Yersinia pseudotuberculosis] gi|79202|pir||
A29646 (1211アミノ酸のうち35%一致)に類似

【００２３】６）線毛に関連するタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 1674： -0.352675, 244, 複製タンパク質
O, 例えばタンパク質 O [Enterobacteria phage HK022]
gi|407289|gb|aaB60272.1| (299アミノ酸のうち98%一
致)に類似 SEQ ID NO: 1129： -0.391449, 422, 複製タンパク質 P
(推定 replicative DNAhelicase), P タンパク質 例え
ば[Enterobacteria phage HK022] gi|6863143|gb|aaF30
384.1|AF069308#32 (478アミノ酸のうち99%一致); repl
icative DNA helicases 例えばDnaB [Escherichia col
i] gi|118713|sp|P03005|DNAB#ECOLI (436アミノ酸のう
ち39%一致)に類似 SEQ ID NO: 1130： -0.275728, 207, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage VT2-Sa] gi|5881620
|dbj|Baa84311.1| (89アミノ酸のうち100%一致)と同じ SEQ ID NO: 1131： -0.090099, 102, 新規, ハイポセテ
ィカルタンパク質 [Bacteriophage 933W] gi|4499788|e
mb|CAB39287.1| (92アミノ酸のうち100%一致)と同じ SEQ ID NO: 1132： -0.513839, 225, type III secreti
on タンパク質, PrgHタンパク質 [Salmonella typhimur
ium] gi|1172612|sp|P41783|PRGH#SALTY (266アミノ酸
のうち28%一致); MxiG [Shigella flexneri] gi|249860
3|sp|Q57332|MXIG#SHIFL (243アミノ酸のうち23%一致)
に類似 SEQ ID NO: 1133： -0.08, 116, 推定 転写調節因子,
転写アクチベーター NtrC[Herbaspirillum seropedica
e] gi|57313501|gb|aaC32391.21 (107アミノ酸のうち25
%一致)に類似 SEQ ID NO: 1134： -0.503734, 483, type III secreti
onタンパク質, type IIIsecretionタンパク質 例えばSp
aSタンパク質 [Salmonella typhimurium] gi|730801|sp
|P40702|SPAS#SALTY (348アミノ酸のうち54%一致)に類
似 SEQ ID NO: 1135： -0.293631, 315, 新規, SEQ ID NO: 1136： -0.452748, 183, ABCトランスポー
ター(結合タンパク質),結合タンパク質 例えばphosphat
e-結合タンパク質 PstS homolog [Methanobacterium th
ermoautotrophicum (strain Delta H)] gi|7442891|pir
||A69098 (187アミノ酸のうち32%一致)に類似 SEQ ID NO: 1137： 0.39434, 54, N-末端部分 (1-77/50
5アミノ酸)がYZGL#ECOLIgi|1789834 (77アミノ酸のうち
83%一致)に類似; C-末端部分(325-519/525アミノ酸)が
結合タンパク質 例えばphosphate-結合タンパク質 PstS
homolog [Methanobacterium thermoautotrophicum str
ain Delta H] gi|7442891|pir||A69098 (175アミノ酸の
うち31%一致)に類似 SEQ ID NO: 1138： 0.390909, 67, 推定 DNA processin
g chain A, many DNA processing chain A (Smf タンパ
ク質), 例えば[Neisseria meningitidis] gi|7378929|e
mb|CAB83472.1| (265アミノ酸のうち30%一致)に類似 SEQ ID NO: 1139： -0.774999, 297, 推定 ATP-依存性
DNA helicase (partial), ATP-依存性DNA helicase [St
reptomyces coelicolor] gi|7480492|pir||T35189のC-
末端部分(37アミノ酸のうち64%一致)に類似, GTGスター
ト SEQ ID NO: 1140： -0.122667, 76, 推定 ATP-依存性 D
NA helicase (partial),ATP-依存性 DNA helicase [Str
eptomyces coelicolor] gi|7480492|pir||T35189の部分
(269アミノ酸のうち31%一致)に類似, GTGスタート SEQ ID NO: 1141： -0.286338, 550, 推定 ATP-依存性
DNA helicase (partial), 推定 ATP-依存性 DNA helica
se [Streptomyces coelicolor] gi|7480492|pir||T3518
9の部分 (175アミノ酸のうち48%一致)に類似 SEQ ID NO: 1142： -0.02069, 59, 推定 ATP-依存性 DN
A helicase (interrupted), 推定 ATP-依存性 DNA heli
cases 例えば[Streptomyces coelicolor] gi|7428315|p
ir||T35189のN-末端部分(176アミノ酸のうち60%一致);
[Bacillus subtilis] gi|7436435|pir||F69901 (169ア
ミノ酸のうち42%一致)に類似 SEQ ID NO: 1143： -0.395745, 330, 新規 SEQ ID NO: 1144： -0.477678, 225, 新規 (ハイポセテ
ィカル膜タンパク質) SEQ ID NO: 1145： -0.43168, 263, 新規 (ハイポセテ
ィカル膜タンパク質) SEQ ID NO: 1146： -0.74642, 434, 新規, ハイポセテ
ィカルタンパク質 ORF79[Escherichia coli プラスミド
pB171] gi|6009455|dbj|Baa84914.1 (175アミノ酸のう
ち62%一致)に類似 SEQ ID NO: 1147： -0.610909, 276, 新規, ハイポセテ
ィカルタンパク質 ORF80[Escherichia coli プラスミド
pB171] (86アミノ酸のうち70%一致)に類似ＳＥＱ Ｉ
Ｄ ＮＯ： １１４８： -0.397973, 297, 新規 (ハイ
ポセティカルリポタンパク質) SEQ ID NO: 1149： -0.965741, 109, 推定 O-methyltra
nsferase, O-methyltransferases 例えばacetylseroton
in N-methyltransferase (EC 2.1.1.4) - chicken gi|2
498445|sp|Q92056|HIOM#CHICK の部分(157アミノ酸のう
ち28%一致)に類似 SEQ ID NO: 1150： -0.836842, 39, 新規 SEQ ID NO: 1151： 0.029565, 116, 推定 acyltransfer
ase, acyltransferases例えば[Neisseria meningitidis
MC58] gi|7226953|gb|aaF42046.1| (246アミノ酸のう
ち33%一致)に類似 SEQ ID NO: 1152： -0.409503, 464, 推定 acyl carrie
rタンパク質, acyl carrierタンパク質 例えば[Neisser
ia meningitidis MC58] gi|7226952|gb|aaF42045.1| (8
5アミノ酸のうち51%一致)に類似 SEQ ID NO: 1153： -0.178846, 53, 推定 acyl carrier
タンパク質, acyl carrierタンパク質 例えば[Neisseri
a meningitidis MC58] gi|7226951|gb|aaF42044.1| (79
アミノ酸のうち51%一致)に類似 SEQ ID NO: 1154： -0.063793, 117, 新規 (ハイポセテ
ィカル膜タンパク質),推定 integral 膜タンパク質 [Ne
isseria meningitidis] gi|7380586|emb|CAB85174.1|
(126アミノ酸のうち51%一致)に類似 SEQ ID NO: 1155： -0.55546, 468, 新規, ペプチドシ
ンセターゼ [Xylella fastidiosa] gi|9105980|gb|aaF8
3848.1|AE003941#2 (420アミノ酸のうち26%一致);p-cou
maryl-CoA ligase [Rhodobacter sphaeroides] gi|2764
724|emb|Caa05380.1|の部分(268アミノ酸のうち27%一
致); surfactin synthetase component I [Bacillus su
btilis] gi|2127235|pir||I40485の部分 (410アミノ酸
のうち20%一致)に類似 SEQ ID NO: 1156： -0.569643, 57, 推定 (3R)-hydroxy
myristoyl-[acyl carrier タンパク質] dehydratase,
(3R)-hydroxymyristoyl-[acyl carrier タンパク質] de
hydratases 例えば[Salmonella typhimurium] gi|14018
2|sp|P21773|FABZ#SALTYの部分 (67アミノ酸のうち29%
一致)に類似(低い) SEQ ID NO: - ： -0.908772, 115, 新規, N-末端部分が
dolichyl-phosphate mannose synthase relatedタンパ
ク質 例えば[Pyrococcus abyssi (strain Orsay)] gi|7
445533|pir||A75176 (206アミノ酸のうち30%一致)に類
似; N-末端部分がHmsR [Yersinia pestis] gi|1185391|
gb|aaB66590.1| (128アミノ酸のうち34%一致)に類似; C
-末端部分がハイポセティカルタンパク質 [Xylella fas
tidiosa] gi|9105669|gb|aaF83585.1|AE003918#7 (310
アミノ酸のうち30%一致)に類似 SEQ ID NO: 1402： 0.001017, 296, 新規, ハイポセテ
ィカルタンパク質 例えば.[Deinococcus radiodurans]
gi|7471367|pir||B75463 (111アミノ酸のうち31%一致)
に類似, GTGスタート SEQ ID NO: 1403： -0.013016, 316, 新規 SEQ ID NO: 1404： 1.044986, 350, 新規, 膜タンパク
質 [Xylella fastidiosa]gi|9105671|gb|aaF83587.1|AE
003918#9 (502アミノ酸のうち24%一致)に類似 SEQ ID NO: 1405： 1.132416, 328, 新規 SEQ ID NO: 1406： -0.004833, 270, 推定 3-oxoacyl-
(acyl-carrier-タンパク質) synthase II, 3-oxoacyl-
(acyl-carrier-タンパク質) synthase II 例えば[Strep
tomyces coelicolor A3(2)] gi|7479090|pir||T34912
(381アミノ酸のうち31%一致)に類似 SEQ ID NO: 1407： -0.402244, 714, 推定 beta-hydrox
ydecanoyl-ACP dehydrase, ハイポセティカルタンパク
質 [Neisseria meningitidis MC58] gi|7226956|gb|aaF
42049.1| (116アミノ酸のうち32%一致); beta-hydroxyd
ecanoyl-ACP dehydrase [Pseudomonas aeruginosa] gi|
2384563|gb|aaC45619.1| (123アミノ酸のうち29%一致)
に類似 SEQ ID NO: - ： -0.405385, 131, 推定 3-oxoacyl-(ac
yl-carrier-タンパク質)reductase, 3-oxoacyl-(acyl-c
arrier-タンパク質) reductases 例えば[Neisseria men
ingitidis MC58] gi|7226957|gb|aaF42050.1| (242アミ
ノ酸のうち57%一致)に類似 SEQ ID NO: 1585： 0.50548, 293, 推定 3-oxoacyl-(ac
yl-carrier-タンパク質)synthase II 例えばgi|7226958
|gb|aaF42051.1| (404アミノ酸のうち48%一致)に類似 SEQ ID NO: 1586： 0.152083, 145, 推定 転写調節因
子, 転写調節因子 例えば[Escherichia coli] gi|12934
7|sp|P13669|FARR#ECOLI (235アミノ酸のうち28%一致)
に類似 SEQ ID NO: 1656： -0.965741, 109, 推定 PTS(phospho
transferase system) system enzyme IIA, PTS system
enzyme IIA components 例えば[Escherichia coli K-1
2] gi|2507274|sp|P37187|PTKA#ECOLI (122アミノ酸の
うち23%一致); PTSsystem frucrose-specific enzyme I
IBC component [Bacillus halodurans] gi|4512375|dbj
|Baa75339.1| (151アミノ酸のうち33%一致)に類似 SEQ ID NO: 1657： -0.397973, 297, 推定 PTS system
enzyme IIB, PTS system, galactitol-specific IIB co
mponent [Escherichia coli K-12] gi|2507273|sp|P371
88|PTKB#ECOLI (92アミノ酸のうち35%一致)に類似 SEQ ID NO: - ： 0.072131, 62, 推定 PTS system enzy
me IIC, PTS system galactitol-specific enzyme IIC
例えば[Bacillus halodurans] gi|4512376|dbj|Baa7534
0.1| (411アミノ酸のうち45%一致)に類似 SEQ ID NO: 1695： 0.74129, 156, 推定 sugar キナー
ゼ, sugar キナーゼ 例えばxyluloキナーゼ (EC 2.7.1.
17) [Lactobacillus pentosus] gi|139850|sp|P21939|X
YLB#LACPE (496アミノ酸のうち23%一致)に類似 SEQ ID NO: 1678： -0.385107, 95, 推定 PTS system H
Pr enzyme, phosphotransferase system HPr enzymes
例えば[Xylella fastidiosa] gi|9106413|gb|aaF84212.
1|AE003971#11 (87アミノ酸のうち39%一致)に類似 SEQ ID NO: 1679： 0.150932, 162, 推定 aldolase, al
dolases 例えば[Vibriofurnissii] gi|1732204|gb|aaC4
4684.1| (272アミノ酸のうち38%一致)に類似 SEQ ID NO: - ： 0.763317, 200, 新規, HicB-related
タンパク質 [Xylella fastidiosa] gi|9106728|gb|aaF8
4477.1|AE003992#13 (110アミノ酸のうち35%一致); Hic
B [Haemophilus influenzae] gi|3603326|gb|aaC35810.
1| (93アミノ酸のうち26%一致)に類似 SEQ ID NO: 1548： -0.459394, 331, 新規, HicA [Haem
ophilus influenzae] gi|3603325|gb|aaC35809.1| (60
アミノ酸のうち30%一致)に類似

【００２４】７）物質の輸送に関連するタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: - ： 0.123763, 506, type III secretion
タンパク質,type III secretion タンパク質 例えばSpa
R タンパク質 [Salmonella typhimurium] gi|730799|sp
|P40701|SPAR#SALTYのC-末端部分 (65アミノ酸のうち56
%一致)に類似, may be partial (disrupted by framesh
ift) SEQ ID NO: 1521： -0.08725, 401, 新規, ハイポセテ
ィカルタンパク質 [Xylella fastidiosa] gi|9112263|g
b|aaF85594.1|AE003851#25 (158アミノ酸のうち48%一
致)に類似 SEQ ID NO: 1522： 0.754902, 52, 新規 SEQ ID NO: 1523： -0.310185, 325, heme utilization
/輸送タンパク質,ChuA [Escherichia coli O157:H7 EDL
933] gi|1763009|gb|aaC44857.1|と同じ SEQ ID NO: 1524： 0.080682, 177, 新規, TTGスタート SEQ ID NO: 1525： -0.081683, 203, 推定 hemin-結合
タンパク質, ハイポセティカルタンパク質huT [Shigell
a dysenteriae haem 輸送 locus] gi|2967538|gb|aaC27
815.1| (304アミノ酸のうち97%一致); hemin-結合タン
パク質 例えば[Yersinia pestis] gi|6226635|sp|Q5699
1|HMUT#YERPE (253アミノ酸のうち34%一致)に類似 SEQ ID NO: 1613： -0.262046, 304, 推定 coproporphy
rinogen oxidase, coproporphyrinogen oxidases 例え
ばPhuW [Vibrio parahaemolyticus gi|5106980|gb|aaD3
9908.1|AF119047#1 (371アミノ酸のうち35%一致)に類似 SEQ ID NO: 1614： 0.671015, 139, 新規, ハイポセテ
ィカルタンパク質huX [Shigella dysenteriae haem 輸
送 locus] gi|2967537|gb|aaC27814.1| (164アミノ酸の
うち98%一致); ハイポセティカルタンパク質 X [Yersin
ia pestis] gi|7467368|pir||T12066 (153アミノ酸のう
ち60%一致)に類似 SEQ ID NO: 1659： -0.222178, 249, 新規, ハイポセテ
ィカルタンパク質huY [Shigella dysenteriae haem 輸
送 locus] gi|2967536|gb|aaC27813.1| (207アミノ酸の
うち97%一致); ハイポセティカルタンパク質 Y [Yersin
ia pestis] gi|7467369|pir||T12067 (204アミノ酸のう
ち55%一致)に類似 SEQ ID NO: - ： -0.069143, 176, 推定 hemin permeas
e, ハイポセティカルタンパク質huU[Shigella dysenter
iae haem 輸送 locus] gi|2967535|gb|aaC27812.1| (31
8アミノ酸のうち99%一致); hemin permeases 例えばHmu
U [Yersinia pestis] gi|6226636|sp|Q56992|HMUU#YERP
E (318アミノ酸のうち66%一致)に類似 SEQ ID NO: 1671： -0.626137, 89, 推定 hemin 輸送系
ATP-結合 タンパク質,ハイポセティカルタンパク質huV
[Shigella dysenteriae haem 輸送 locus] gi|2967534
|gb|aaC27811.1| (256アミノ酸のうち98%一致); hemin
輸送系ATP-結合タンパク質 例えばHmuV [Yersinia pest
is] gi|2492539|sp|Q56993|HMUV#YERPE(264アミノ酸の
うち58%一致)に類似 SEQ ID NO: 1241： -0.4456, 126, 推定 fimbrial タン
パク質前駆体, fimbrialタンパク質 例えばlong polar
fimbrial minor タンパク質前駆体 [Salmonellatyphimu
rium] gi|1170819|sp|P43664|LPFE#SALTY (165アミノ酸
のうち50%一致)に類似 SEQ ID NO: 1242： 0.022946, 354, 推定 fimbrial タ
ンパク質前駆体, fimbrialタンパク質 例えばlong pola
r fimbrial タンパク質 LpfD [Salmonella typhimuriu
m] gi|1170818|sp|P43663|LPFD#SALTY (350アミノ酸の
うち39%一致)に類似 SEQ ID NO: 1243： -0.201546, 195, 推定 外膜usherタ
ンパク質LpfC前駆体 (partial), 外膜 usherタンパク質
例えばLpfC前駆体 [Salmonella typhimurium] gi|1170
817|sp|P43662|LPFC#SALTYのC-末端半分(485アミノ酸の
うち67%一致)に類似, GTGスタート SEQ ID NO: 1244： 0.154275, 270, 推定 外膜usherタ
ンパク質, 外膜usherタンパク質 例えばLpfC [Salmonel
la typhimurium] gi|1170817|sp|P43662|LPFC#SALTYのN
-末端半分 (357アミノ酸のうち69%一致)に類似, interr
upted TAG stop codon SEQ ID NO: 1245： 0.251765, 86, 推定 fimbrial chap
eroneタンパク質, chaperones 例えばLpfB [Salmonella
typhimurium] gi|1170816|sp|P43661|LPFB#SALTY (229
アミノ酸のうち67%一致)に類似 SEQ ID NO: 1246： -0.375904, 84, 推定 fimbrial maj
orタンパク質前駆体, long polar fimbriaタンパク質A
前駆体, LpfA, of S. typhimurium, gi|1170815|sp|P43
660|LPFA#SALTY (178アミノ酸のうち73%一致)に類似 SEQ ID NO: 1247： 0.721244, 194, 推定 転写調節因
子, ハイポセティカル転写調節isR [Bacillus subtili
s] gi|3123306|sp|P40331 (276アミノ酸のうち24%一致)
に類似(低い) SEQ ID NO: 1248： -0.13819, 454, 推定 permease, ハ
イポセティカルタンパク質 [Salmonella typhimurium]
gi|7442781|pir||C65167 (444アミノ酸のうち37%一致);
輸送 タンパク質 (推定 symporters) 例えばYicJ [Esc
herichia coli (K-12)] gi|2851421|sp|P31435|YICJ#EC
OLI (340アミノ酸のうち32%一致)に類似 SEQ ID NO: 1249： -0.388034, 118, 新規, ハイポセテ
ィカルタンパク質 [Thermotoga maritima] gi|7452109|
pir||F72395 (635アミノ酸のうち37%一致)に類似 SEQ ID NO: 1250： -0.070968, 559, 新規, ハイポセテ
ィカルタンパク質 [Neisseria meningitidis MC58] gi|
7227012|gb|aaF42100.1 (398アミノ酸のうち39%一致)に
類似 SEQ ID NO: 1251： -0.387143, 141, 新規, TTGスター
ト SEQ ID NO: 1252： -0.435323, 202, 新規, TTGスター
ト SEQ ID NO: 1253： 0.383311, 750, 新規, surfaceタン
パク質, 例えば.[Xylella fastidiosa] gi|9106565|gb|
aaF84338.1|AE003982#11 (1514アミノ酸のうち24%一致)
に類似 SEQ ID NO: 1254： -0.125258, 195, lipid A-core:sur
face polymer ligase (WaaL), WaaL [Escherichia coli
strain F653] gi|3821825|gb|aaC69661.1| (402アミノ
酸のうち100%一致)と同じ SEQ ID NO: 1255： -0.00874, 390, lipopolysaccharid
e 1,2-N acetylglucosaminetransferase (WaaD), WaaD
[Escherichia coli strain F653] gi|3821826|gb|aaC69
662.1| (380アミノ酸のうち99%一致)に類似 SEQ ID NO: 1256： 0.065584, 155, 推定 UDP-glucose:
(galactosyl) LPS alpha1,2-glucosyltransferase (Waa
J), UDP-glucose:(galactosyl) LPS alpha1,2-glucosyl
transferase WaaJ [Escherichia coli strain F653] gi
|3821827|gb|aaC69663.1| (184アミノ酸のうち98%一致)
に類似, TTG スタート SEQ ID NO: 1257： 0.147325, 244, lipopolysaccharid
e core biosynthesis, WaaY [Escherichia coli strain
F653] gi|3821828|gb|aaC69664.1| (235アミノ酸のう
ち100%一致)と同じ SEQ ID NO: - ： -0.156479, 410, UDP-D-galactose:(g
lucosyl)lipopolysaccharide- alpha-1,3-D-galactosyl
transferase, WaaI (strain F653 R3 core type)[Esche
richia coli] gi|3821829|gb|aaC69665.1 (335アミノ酸
のうち99%一致)に類似 SEQ ID NO: 1427： -0.248606, 252, 新規 SEQ ID NO: 1428： 0.024841, 158, 推定 インテグラー
ゼ, CP4-様 インテグラーゼ [Escherichia coli EDL93
3] gi|3414871|gb|aaC31482.1|と同じ;インテグラーゼ
例えば[Shigella flexneri] gi|5532446|gb|aaD44730.1
|AF141323#1 (390アミノ酸のうち95%一致)に類似 SEQ ID NO: 1429： 0.37957, 94, 新規, L0004 [Escher
ichia coli strain EDL933] gi|3414872|gb|aaC31483.1
|と同じ; ハイポセティカルタンパク質 例えば[Escheri
chia coli プラスミドpO157 insertion sequence IS911
gi|7465897|pir||T00224 (116アミノ酸のうち56%一致)
に類似, GTGスタート SEQ ID NO: 1430： 0.897123, 453, 新規, L0005 [Esch
erichia coli strain EDL933] gi|3414873|gb|aaC3148
4.1|と同じ, GTGスタート SEQ ID NO: 1431： -0.065339, 503, 新規, L0006 [Esc
herichia coli strain EDL933] gi|3414874|gb|aaC3148
5.1|と同じ; ハイポセティカルタンパク質 例えば[Vibr
io cholerae] gi|7960027|gb|aaF71187.1|AF179596#7
(300アミノ酸のうち60%一致)に類似 SEQ ID NO: 1432： -0.496629, 90, 新規, ハイポセテ
ィカルタンパク質 例えばb2004 (YeeU) [Escherichia c
oli] gi|3025157|sp|P76364|YEEU#ECOLIのC-末端部分
(53アミノ酸のうち84%一致)に類似 SEQ ID NO: 1433： -0.054196, 287, 新規, L0007 [Esc
herichia coli EDL933]gi|3414875|gb|aaC31486.1|と同
じ; ハイポセティカルタンパク質 例えばb2005(yeeV)
[Escherichia coli] gi|3025158|sp|P76365|YEEV#ECOLI
(124アミノ酸のうち88%一致)に類似 SEQ ID NO: 1434： -0.327731, 120, 新規, L0008 [Esc
herichia coli EDL933]gi|3414876|gb|aaC31487.1|と同
じ; ハイポセティカルタンパク質 [Escherichiacoli D1
114, O25:K10:H16] gi|4887094|gb|aaD32187.1| (114ア
ミノ酸のうち90%一致)に類似; b2006 (YeeW) [Escheric
hia coli] gi|3025160|sp|P76366|YEEW#ECOLI (55アミ
ノ酸のうち70%一致)に類似 SEQ ID NO: 1435： -0.472528, 92, 新規, L0009 [Esch
erichia coli strain EDL933] gi|3414877|gb|aaC3148
8.1|と同じ; ハイポセティカルタンパク質 [Escherichi
a coli D1114, O25:K10:H16] gi|4887094|gb|aaD32187.
1|(59アミノ酸のうち84%一致); ハイポセティカルタン
パク質 [Salmonella typhi] gi|7800330|gb|aaF69926.1
|AF250878#87 (49アミノ酸のうち46%一致)に類似 SEQ ID NO: 1339： -0.276608, 343, 新規, L0010 [Esc
herichia coli strain EDL933] gi|3414878|gb|aaC3148
9.1|と同じ; PH01 [Escherichia coli D1114, O25:K10:
H16] gi|4887092|gb|aaD32185.1|AF127177#3 (78アミノ
酸のうち62%一致)に類似 SEQ ID NO: 1340： -0.474091, 661, 新規, ハイポセテ
ィカルタンパク質 ydiA[プラスミド ColIb-P9] gi|4512
489|dbj|Baa75138.1|の部分 (35のうち42%一致)に類似
(低い) SEQ ID NO: 1341： -0.667647, 69, 新規, L0012 [Esch
erichia coli EDL933] gi|3414880|gb|aaC31491.1|と同
じ; 推定 ATP-結合 タンパク質ugR [Salmonellatyphimu
rium] gi|4324607|gb|aaD16951.1|の部分 (66アミノ酸
のうち45%一致)に類似 SEQ ID NO: 1342： 0.113158, 305, 新規, L0013 [Esch
erichia coli EDL933] gi|3414881|gb|aaC31492.1|と同
じ; ハイポセティカルタンパク質 例えばHp3 [Escheric
hia coli CFT073] gi|3661484|gb|aaC61715.1| (74アミ
ノ酸のうち100%一致)に類似 SEQ ID NO: 1343： -0.308539, 446, 新規, L0014 [Esc
herichia coli] gi|3414882|gb|aaC31493.1|と同じ; ハ
イポセティカルタンパク質 例えばorf50 [Escherichia
coli プラスミド pB171] gi|6009426|dbj|Baa84885.1|
(107アミノ酸のうち76%一致)に類似 SEQ ID NO: 1344： -0.137195, 165, 新規, L0015 [Esc
herichia coli EDL933]gi|3414883|gb|aaC31494.1| (51
2アミノ酸のうち99%一致); ハイポセティカルタンパク
質 例えば[Escherichia coli プラスミド pEAF] gi|480
8945|gb|aaD30027.1|AF119170#2 (447アミノ酸のうち91
%一致)に類似 SEQ ID NO: 1345： 0.057488, 208, 新規, IS630 inser
tion element ハイポセティカルタンパク質 gi|1143207
|gb|aaA84873.1|の部分 (25アミノ酸のうち72%一致)に
類似 SEQ ID NO: 1346： 0.933648, 319, 新規, ハイポセテ
ィカルタンパク質 例えば[insertion sequence IS91] g
i|7466597|pir||T00311の部分(49アミノ酸のうち75%一
致)に類似 SEQ ID NO: 1347： -0.269531, 257, secreted effecto
rタンパク質, L0016 [Escherichia coli EDL933] gi|34
14884|gb|aaC31495.1|と同じ; EspF [Escherichia coli
E2348/69] gi|2865308|gb|aaC38400.1| (205アミノ酸
のうち87%一致)に類似 SEQ ID NO: 1461： -0.092614, 177, 新規, L0017 [Esc
herichia coli EDL933]gi|3414885|gb|aaC31496.1|と同
じ; ハイポセティカルタンパク質 例えば[Escherichia
coli] gi|2809428|gb|aaC28566.1| (92アミノ酸のうち9
7%一致)に類似 SEQ ID NO: 1462： -0.045584, 352, 新規, EscF [Esch
erichia coli] gi|2865306|gb|aaC38398.1|; L0018 [Es
cherichia coli EDL933] gi|3414886|gb|aaC31497.1|と
同じ SEQ ID NO: 1463： -0.460825, 486, 新規, L0019 [Esc
herichia coli EDL933]gi|3414887|gb|aaC31498.1|と同
じ; ハイポセティカルタンパク質 例えばOrf27[Escheri
chia coli E2348/69] gi|2865305|gb|aaC38397.1| (135
アミノ酸のうち99%一致)に類似 SEQ ID NO: 1464： -0.264578, 368, EspBタンパク質
(secretedタンパク質), EspB タンパク質 例えばEspB(L
0020) [Escherichia coli EDL933] gi|1657263|emb|Caa
65654.1| (312アミノ酸のうち99%一致)に類似 SEQ ID NO: 1465： -0.234061, 230, EspD secretedタ
ンパク質, L0021 [Escherichia coli EDL933] gi|34148
89|gb|aaC31500.1|と同じ; EspD タンパク質 例えばgi|
3688279|emb|Caa76909.1| (374アミノ酸のうち85%一致)
に類似 SEQ ID NO: 1466： 0.12809, 179, EspA secreted タン
パク質, EspA タンパク質 (L0022) [Escherichia coli]
gi|3115184|emb|Caa73506.1|と同じ; EspAタンパク質
例えばgi|2388623|gb|aaB71083.1| (192アミノ酸のうち
85%一致)に類似 SEQ ID NO: - ： -0.31476, 272, type III secretion
system SepLタンパク質,SepL (L0023) [Escherichia co
li EDL933] gi|3115183|emb|Caa73505.1|と同じ;SepL
タンパク質 例えばgi|2865301|gb|aaC38393.1| (351ア
ミノ酸のうち94%一致)に類似 SEQ ID NO: 1507： 0.694205, 467, type III secretio
n system EscDタンパク質, Pas (L0024) [Escherichia
coli EDL933] gi|3115182|emb|Caa73504.1|と同じ; Esc
D タンパク質 例えばgi|3341420|emb|Caa74170.1| (406
アミノ酸のうち97%一致)に類似 SEQ ID NO: - ： -0.414177, 657, Gamma intimin, Gam
ma intimin (L0025) [Escherichia coli strain EDL93
3] gi|3414893|gb|aaC31504.1|と同じ SEQ ID NO: - ： -0.310441, 432, chaperon of Tir, C
esT [Escherichia coliO157:H7 strain HA1] gi|975876
|gb|aaB00110.1|と同じ; CesTタンパク質 [Escherichia
coli] gi|140611|sp|P21244|YEAE#ECOLI (156アミノ酸
のうち96%一致)に類似 SEQ ID NO: - ： -0.190991, 112, translocated intim
in レセプター Tir, translocated intimin レセプター
Tir (L0027) [Escherichia coli O157:H7 strain EDL9
33] gi|3414895|gb|aaC31506.1|と同じ

【００２５】８）リポ多糖合成に関連するタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 1458： -0.456995, 194, 新規 SEQ ID NO: 1459： -0.234382, 1589, 新規 SEQ ID NO: 1367： 0.565175, 403, 新規 SEQ ID NO: 1368： -0.187369, 381, 新規 SEQ ID NO: 1369： -0.401484, 338, 新規 SEQ ID NO: 1370： -0.385532, 236, 新規, ankyrin-様
調節タンパク質 [Escherichia coli] gi|418526|sp|P23
325|APR#ECOLI (606アミノ酸のうち24%一致); ShET2 en
terotoxin [Shigella flexneri] gi|1109754|emb|Caa90
938.1| (465アミノ酸のうち23%一致)に類似 SEQ ID NO: 1371： -0.356119, 336, 新規, ハイポセテ
ィカルタンパク質 例えば[Plasmodium falciparum] gi|
8052285|emb|CAB39037.2| (688アミノ酸のうち21%一
致); restriction-modification enzyme R subunits [M
ycoplasma pulmonis] 例えばgi|1363459|pir||S49394
(441アミノ酸のうち20%一致)に類似(低い) SEQ ID NO: - ： -0.124419, 173, 新規 SEQ ID NO: 817： -0.482697, 394, 新規, TTG スター
ト SEQ ID NO: 818： -0.793965, 117, 新規 SEQ ID NO: 819： -0.12, 61, 新規, ハイポセティカル
タンパク質 例えば[Plasmodium falciparum] gi|805229
0|emb|CAB39073.2| (426アミノ酸のうち21%一致)に類似
(低い), TTGスタート SEQ ID NO: 820： -0.640092, 218, 新規 SEQ ID NO: 821： -0.495745, 48, 新規 SEQ ID NO: 822： -0.308064, 125, 推定 fimbrialタン
パク質, fimbrialタンパク質 例えば[Salmonella typhi
murium] gi|1170818|sp|P43663|LPFD#SALTY (336アミノ
酸のうち24%一致); [Escherichia coli] gi|3915422|sp
|P75858|YCBT#ECOLI (337アミノ酸のうち27%一致)に類
似 SEQ ID NO: 823： 0.062577, 164, 推定 fimbrial タン
パク質, fimbrial タンパク質 例えば[Escherichia col
i] gi|3915422|sp|P75858|YCBT#ECOLI (352アミノ酸の
うち25%一致); [Salmonella typhimurium] gi|1170818|
sp|P43663|LPFD#SALTY (331アミノ酸のうち24%一致)に
類似 SEQ ID NO: 824： -0.304615, 66, 推定 外膜usherタン
パク質前駆体, 外膜usherタンパク質前駆体 例えば[Sal
monella typhimurium] gi|1170817|sp|P43662|LPFC#SAL
TY (833アミノ酸のうち40%一致); [Escherichia coli]
gi|2829634|sp|P75857|YCBS#ECOLI (819アミノ酸のうち
39%一致)に類似 SEQ ID NO: 825： -0.055752, 114, 新規, fimbrial ch
aperone 例えばgi|1169720|sp|P46008|FOCC#ECOLIの部
分 (44アミノ酸のうち34%一致)に類似

【００２６】９）代謝に関連するタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 826： -0.36383, 48, 新規, ハイポセティ
カルタンパク質[Bacteriophage 933W] gi|4499789|emb|
CAB39288.1| (71アミノ酸のうち97%一致)に類似 SEQ ID NO: 827： -0.877049, 62, 推定 fimbrial chap
erone, fimbrial chaperones 例えば[Salmonella typhi
murium] gi|1170816|sp|P43661|LPFB#SALTY (104アミノ
酸のうち40%一致)に類似 SEQ ID NO: 828： -0.388722, 134, 推定 type 1 fimbr
ialタンパク質, type 1fimbrialタンパク質 例えば[Sal
monella enteritidis] gi|913907|gb|aaB33536.1| (198
アミノ酸のうち31%一致)に類似 SEQ ID NO: 829： 0.010435, 116, 新規, conserved ハ
イポセティカルタンパク質 例えばHP0709 [Helicobacte
r pylori 26695] gi|7463979|pir||E64608 (300アミノ
酸のうち88%一致)に類似 SEQ ID NO: 830： -0.455859, 513, 新規, ハイポセテ
ィカルタンパク質 [Xylella fastidiosa] gi|9104946|g
b|aaF82968.1|AE003869#5 (270アミノ酸のうち33%一致)
に類似 SEQ ID NO: 831： -0.335065, 78, 新規 (ハイポセティ
カル膜タンパク質) SEQ ID NO: 832： -1.205882, 52, 新規, 膜タンパク質
[Staphylococcus aureus] gi|3676428|gb|aaC61946.1
(236アミノ酸のうち26%一致) に類似(低い) SEQ ID NO: 833： -0.434677, 249, 新規 SEQ ID NO: 834： 0.071739, 93, 新規, GTGスタート SEQ ID NO: 835： -0.190411, 74, 新規, GTGスタート SEQ ID NO: 836： -0.322222, 136, raffinose metabol
ism (putativ例えばlycoタンパク質), RafY [Escherich
ia coli プラスミド pRSD2] gi|1773072|gb|aaB71432.1
(464アミノ酸のうち78%一致)に類似 SEQ ID NO: 837： -0.195833, 313, 新規 SEQ ID NO: 838： -0.038235, 375, 新規 (ハイポセテ
ィカル膜タンパク質) SEQ ID NO: 839： -0.158854, 193, Rhsタンパク質, Rh
sタンパク質 例えばRhsF[Escherichia coli] gi|292063
7|gb|aaC32473.1| (1394アミノ酸のうち97%一致)に類
似, [RhsH coreタンパク質 with extension] SEQ ID NO: 840： -0.174074, 352, 新規 SEQ ID NO: 841： -0.092611, 407, 推定 アミノ酸amid
ohydrolase, アミノ酸amidohydrolases 例えばbenzoylg
lycine amidohydrolase (Hippuricase) [Campylobacter
jejuni] gi|1170277|spP45493|HIPO#CAMJE (383アミノ
酸のうち46%一致)に類似 SEQ ID NO: 842： -0.384796, 935, 推定 膜輸送タンパ
ク質, 膜輸送 タンパク質 例えばcitrate-proton sympo
rter [Klebsiella pneumoniae] gi|116482|sp|P16482|C
IT1#KLEPN (429アミノ酸のうち30%一致)に類似 SEQ ID NO: 843： -0.174359, 157, 新規, ハイポセテ
ィカルタンパク質 b3122[Escherichia coli (strain K-
12)] gi|7466507|pir||G65101 (35アミノ酸のうち62%一
致)に類似 SEQ ID NO: 844： -0.563799, 559, 推定 L-sorbose 1-
phosphate dehydrogenase, L-sorbose 1-phosphate deh
ydrogenases, 例えば[Klebsiella pneumoniae] gi|5860
14|sp|P37084|SORE#KLEPN (407アミノ酸のうち85%一致)
に類似 SEQ ID NO: 845： -0.552709, 204, 推定 sorbose-perm
ease IID component (PTS system), many sorbose-perm
ease IID components 例えばgi|548634|sp|P37083|PTRD
#KLEPN (215アミノ酸のうち95%一致)に類似, probably
disrupted (N-末端部分(1-60アミノ酸)が欠失) SEQ ID NO: 846： -0.058268, 128, 推定調節因子 (リ
プレッサー), N-末端半分がハイポセティカルタンパク
質 HI1476 [Haemophilus influenzae]gi|1175815|sp|P4
4207|YE76#HAEIN (70アミノ酸のうち35%一致)に類似; C
-末端半分が推定 リプレッサータンパク質 [Bacterioph
age D108] gi|133345|sp|P07040|RPC1#BPD10(79アミノ
酸のうち26%一致)に類似 SEQ ID NO: 847： -0.457738, 169, 推定 DNA-結合タン
パク質, Ner-様DNA-結合タンパク質 例えばgi|6900348|
emb|CAB71960.1| (70アミノ酸のうち44%一致)に類似 SEQ ID NO: 848： -0.023279, 306, 推定 phage transp
osase, transposases 例えば[Neisseria meningitidis]
gi|7379960|emb|CAB84536.1| (639アミノ酸のうち40 %
一致)に類似 SEQ ID NO: 849： -0.484058, 139, transpositionタン
パク質, DNA transpositionタンパク質B [Bacteriophag
e Mu] gi|139318|sp|P03763|VPB#BPMU (298アミノ酸の
うち48%一致)に類似 SEQ ID NO: 850： -0.9296, 126, 新規, phosphoserine
phosphatase [Neisseria meningitidis MC58] gi|7226
221|gb|aaF41385.1| (49アミノ酸のうち38%一致)に類似
(低い) SEQ ID NO: 851： 0.013677, 447, 新規 SEQ ID NO: 852： 0.371556, 676, 新規, GTGスタート SEQ ID NO: 853： 0.247863, 118, 新規, GTGスタート SEQ ID NO: 854： 0.445454, 100, 新規 SEQ ID NO: 855： -0.008451, 143, 推定 host-ヌクレ
アーゼインヒビター, host-ヌクレアーゼインヒビター
タンパク質 (Gam) 例えば[Bacteriophage Mu] gi|13812
7|sp|P06023|VGAM#BPMU (174アミノ酸のうち56%一致)に
類似 SEQ ID NO: 856： -0.096842, 191, 新規 SEQ ID NO: 857： -0.295364, 152, 新規, Gp11 [Bacte
riophage Mu] gi|6010385|gb|aaF01088.1|AF083977#7
(177アミノ酸のうち67%一致)に類似 SEQ ID NO: 858： -0.149414, 513, 新規, gp12 [Bacteriophage Mu] gi|215568|gb|aaA32400.1|
(168アミノ酸のうち52%一致)に類似 SEQ ID NO: 859： -0.454967, 152, 新規, gp9 [Bacter
iophage Mu] gi|6010430|gb|aaF01133.1|AF083977#54
(82アミノ酸のうち30%一致)に類似 SEQ ID NO: 860： -0.538686, 138, 新規 SEQ ID NO: 861： -0.001626, 124, 新規, zinc finger
タンパク質 例えば[Rattus norv例えばicus] gi|141712
|sp|P18745|ZO22#XENLA (48アミノ酸のうち33%一致) に
類似(低い) SEQ ID NO: 862： -0.207895, 153, 新規 SEQ ID NO: 863： 0.275652, 346, 新規, ハイポセティ
カルタンパク質 例えばgp16 [Bacteriophage Mu] gi|60
10390|gb|aaF01093.1|AF083977#12 (162アミノ酸のうち
43%一致)に類似ＳＥＱ ＩＤ ＮＯ： ８６４： 1.013
566, 259, 推定 後期転写のpositive調節因子, 転写調
節因子 例えば後期転写のpositive 調節因子(タンパク
質 C) [Bacteriophage Mu] gi|139320|sp|P06022|VPC#B
PMU (126アミノ酸のうち39%一致)に類似 SEQ ID NO: 865： 1.206742, 90, endolysin (host cel
l lysis), endolysins例えばLys [Bacteriophage Mu] |
126600|sp|P27359|LYCV#BPP21 (156アミノ酸のうち37%
一致)に類似 SEQ ID NO: 866： 0.813365, 218, 新規, P14 [Bacteri
ophage APSE-1] gi|6118009|gb|aaF03957.1|AF157835#1
4 (82アミノ酸のうち27%一致)に類似, GTGスタート SEQ ID NO: 867： -0.361905, 232, 新規, P16 [Bacter
iophage APSE-1] gi|6118011|gb|aaF03959.1|AF157835#
16 (81アミノ酸のうち46%一致)に類似 SEQ ID NO: 868： -0.288945, 200, 新規, traR famil
y, 例えばOrf82 [Bacteriophage P2] gi|732223|sp|Q06
424|YO82#BPP2 (34アミノ酸のうち52%一致)に類似 SEQ ID NO: 869： -0.829907, 108, 新規, gp25 [Bacte
riophage Mu] gi|6010400|gb|aaF01103.1|AF083977#22
(91アミノ酸のうち35%一致)に類似 SEQ ID NO: 870： -0.475, 73, 新規, ハイポセティカ
ルタンパク質 例えばgp26[Bacteriophage Mu] gi|60104
01|gb|aaF01104.1|AF083977#23 (95アミノ酸のうち62%
一致)に類似 SEQ ID NO: 871： -0.715504, 130, 新規, ハイポセテ
ィカルタンパク質 例えばgp27 [Bacteriophage Mu] gi|
6010402|gb|aaF01105.1|AF083977#24 (193アミノ酸のう
ち56%一致)に類似 SEQ ID NO: 872： 0.351219, 42, 推定 portalタンパク
質, ハイポセティカルタンパク質 例えばgp28 (possibl
e portal タンパク質 H) [Bacteriophage Mu] gi|60104
03|gb|aaF01106.1|AF083977#25 (537アミノ酸のうち73%
一致)に類似 SEQ ID NO: 873： -0.262814, 399, 新規, ハイポセテ
ィカルタンパク質 例えばgp29 [Bacteriophage Mu] gi|
6010404|gb|aaF01107.1|AF083977#26 (529アミノ酸のう
ち57%一致)に類似 SEQ ID NO: 874： -0.127574, 273, 新規, ハイポセテ
ィカルタンパク質 例えばgp30 [Bacteriophage Mu] gi|
6010405|gb|aaF01108.1|AF083977#27 (437アミノ酸のう
ち60%一致)に類似 SEQ ID NO: 875： -0.857143, 78, virion morphogenes
is, Gタンパク質 [Bacteriophage Mu] gi|267389|sp|Q0
1261|VPG#BPMU (151アミノ酸のうち53%一致)に類似 SEQ ID NO: - ： -0.821875, 65, potential プロテア
ーゼタンパク質, gpI [Bacteriophage Mu] gi|7226336|
gb|aaF41489.1| (369アミノ酸のうち31%一致)に類似, SEQ ID NO: 1686： -0.40171, 118, 推定 major head s
ubunit, タンパク質T [Bacteriophage Mu] gi|6010409|
gb|aaF01112.1|AF083977#31 (311アミノ酸のうち66%一
致); ハイポセティカルタンパク質 例えば[Neisseria m
eningitidis] gi|6900377|emb|CAB71989.1|(311アミノ
酸のうち50%一致)に類似 SEQ ID NO: 1687： -0.015888, 108, 新規, gp35 [Bact
eriophage Mu] gi|6010410|gb|aaF01113.1|AF083977#32
(62アミノ酸のうち40%一致)に類似 SEQ ID NO: 1533： -0.455151, 331, 新規, ハイポセテ
ィカルタンパク質 例えばgp36 [Bacteriophage Mu] gi|
6010411|gb|aaF01114.1|AF083977#33 (139アミノ酸のう
ち46%一致)に類似 SEQ ID NO: 1534： -0.761539, 105, 新規, ハイポセテ
ィカルタンパク質 例えばgp37 [Bacteriophage Mu] gi|
1175870|sp|P44231|YF09#HAEIN (187アミノ酸のうち33%
一致)に類似 SEQ ID NO: 1535： -0.293125, 161, 新規, ハイポセテ
ィカルタンパク質 例えばgp38 [Bacteriophage Mu] gi|
6010413|gb|aaF01116.1|AF083977#35 (52アミノ酸のう
ち54%一致)に類似 SEQ ID NO: 1536： -0.370046, 218, major tail subun
it (sheathタンパク質),sheathタンパク質 GpL [Bacter
iophage Mu] gi|1834291|dbj|Baa19195.1| (499アミノ
酸のうち51%一致); ハイポセティカルタンパク質 例え
ば[Haemophilus influenzae Rd] gi|1175872|sp|P44233
|YF11#HAEIN (499アミノ酸のうち40%一致)に類似 SEQ ID NO: 1564： -0.396053, 77, 新規, ハイポセテ
ィカルタンパク質 例えばGpM [Bacteriophage Mu] gi|1
834292|dbj|Baa酸19196.1| (120アミノ酸のうち49%一
致)に類似 SEQ ID NO: 1565： -0.199849, 663, 新規, ハイポセテ
ィカルタンパク質 例えばORF3 [Bacteriophage Mu] gi|
1834293|dbj|Baa19197.1| (122アミノ酸のうち49%一致)
に類似

【００２７】１０）ＤＮＡ／ＲＮＡのプロセッシングに
関連するタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 1395： -0.645885, 803, type III secreti
on タンパク質 (surfacepresentation of antigens),
推定 type III secretionタンパク質 例えばSpaRタンパ
ク質 (surface presentation of antigens) [Salmonell
a typhimurium] gi|730799|sp|P40701|SPAR#SALTYのN-
末端部分 (144アミノ酸のうち44%一致)に類似, probabl
y interrupted SEQ ID NO: 1396： -0.414798, 224, type III secreti
onタンパク質, type IIIsecretionタンパク質 例えばSp
aQ [Salmonella enterica] gi|975756|gb|aaC43847.1|
(86アミノ酸のうち68%一致)に類似 SEQ ID NO: 1397： -0.230128, 157, type III secreti
onタンパク質, type IIIsecretionタンパク質 例えばSp
aP [Salmonella enterica] gi|975755|gb|aaC43846.1|
(218アミノ酸のうち69%一致)に類似 SEQ ID NO: 1398： 0.60339, 60, type III secretion
タンパク質, type III secretionタンパク質 例えばSpa
O [Salmonella enterica] gi|973277|gb|aaC43944.1|
(292アミノ酸のうち32%一致)に類似 SEQ ID NO: 1399： -0.623677, 795, type III secreti
onタンパク質, type IIIsecretion タンパク質 例えばS
paN [Salmonella enterica] gi|1155289|gb|aaC44993.1
|のC-末端部分(82アミノ酸のうち38%一致)に類似, TTG
スタート SEQ ID NO: 1400： -0.241304, 47, 新規 SEQ ID NO: - ： -0.288136, 60, type III secretion
タンパク質, type III secretionタンパク質 例えばSpa
M [Salmonella enterica] gi|1155297|gb|aaC44998.1|
(146アミノ酸のうち29%一致)に類似 SEQ ID NO: 1412： -0.074167, 361, 推定 tape measur
eタンパク質, ハイポセティカルタンパク質 例えばGp42
(推定 tape measureタンパク質) [Bacteriophage Mu]
gi|6010417|gb|aaF01120.1|AF083977#39 (686アミノ酸
のうち36%一致)に類似 SEQ ID NO: 1413： -0.064607, 357, 推定 DNA circula
tionタンパク質, DNA circulationタンパク質 例えばタ
ンパク質 N [Bacteriophage Mu] gi|6010418|gb|aaF011
21.1|AF083977#40 (441アミノ酸のうち33%一致)に類似 SEQ ID NO: 1414： -0.374289, 845, 推定 tailタンパ
ク質, tailタンパク質 例えばP タンパク質 [Bacteriop
hage Mu] gi|139353|sp|P08558|VPP#BPMU (360アミノ酸
のうち47%一致)に類似, GTGスタート SEQ ID NO: 1415： 0.2, 54, 新規, ハイポセティカル
タンパク質 例えばgp45 [Bacteriophage Mu] gi|601042
0|gb|aaF01123.1|AF083977#42 (195アミノ酸のうち51%
一致)に類似, may be involved in base plate assembl
y SEQ ID NO: 1416： -0.05748, 128, 新規, ハイポセテ
ィカルタンパク質 例えばGp46 [Bacteriophage Mu] gi|
6010421|gb|aaF01124.1|AF083977#43 (144アミノ酸のう
ち53%一致)に類似 SEQ ID NO: 1417： -0.1945, 201, 新規, ハイポセティ
カルタンパク質 例えばGp47 [Bacteriophage Mu] gi|60
10422|gb|aaF01125.1|AF083977#44 (360アミノ酸のうち
53%一致)に類似 SEQ ID NO: 1661： -0.169, 301, 新規, ハイポセティ
カルタンパク質 例えばGp48 [Bacteriophage Mu] gi|60
10423|gb|aaF01126.1|AF083977#45 (183アミノ酸のうち
48%一致)に類似 SEQ ID NO: 1556： -0.241844, 283, 推定 tail fiber,
Sタンパク質 [Bacteriophage Mu] gi|6010424|gb|aaF0
1127.1|AF083977#46 (198アミノ酸のうち46%一致); ハ
イポセティカルタンパク質 例えばBcv [Shigella boydi
i] gi|96900|pir||A42463 (78アミノ酸のうち56%一致)
に類似 SEQ ID NO: 1557： 0.691919, 100, 推定 tail fiber a
ssemblyタンパク質, unnamedタンパク質 product [Bact
eriophage 186] gi|3522882|gb|aaC34165.1| (173アミ
ノ酸のうち39%一致); tail fiber assemblyタンパク質
例えばUタンパク質[Bacteriophage Mu] gi|6010425|gb|
aaF01128.1|AF083977#47 (176アミノ酸のうち28%一致)
に類似 SEQ ID NO: 1667： 1.052233, 292, tail fiberタンパ
ク質 (partial)のC-末端部分, tail fiber タンパク質
例えばS [Bacteriophage Mu] gi|6010424|gb|aaF01127.
1|AF083977#46のC-末端部分 (65アミノ酸のうち38%一
致)に類似 SEQ ID NO: - ： -0.43064, 298, 推定 invertase, sit
e-specific recombinases 例えばDNA-invertas例えばin
[Bacteriophage Mu] gi|6010426|gb|aaF01129.1|AF083
977#50 (181アミノ酸のうち75%一致)に類似 SEQ ID NO: 1600 -0.069079, 305, 新規, ハイポセテ
ィカルタンパク質 例えばL0105 [Bacteriophage 933W]
gi|4585419|gb|aaD25447.1|AF125520#42 (614アミノ酸
のうち73%一致)に類似 SEQ ID NO: - ： -0.338889, 73, 新規, orf25 [Bacter
iophage 933W] gi|4499806|emb|CAB39305.1| (57アミノ
酸のうち52%一致)に類似 SEQ ID NO: 1616： -0.524138, 465, 新規, ハイポセテ
ィカルタンパク質 例えばL0106 [Bacteriophage 933W]
gi|4585420|gb|aaD25448.1|AF125520#43 (79アミノ酸の
うち41%一致)に類似 SEQ ID NO: 1630： -0.041597, 239, 新規

【００２８】１１）病原性に関連するタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 1631： 0.342857, 225, type III secretio
nタンパク質 (ATP synthetase), 推定 type III secret
ion タンパク質 (ATP synthetase) 例えばinvC [Salmon
ella typhimurium] gi|730791|sp|P39444|SPAL#SALTY
(63のうち387アミノ酸%一致)に類似 SEQ ID NO: 1472： -0.763847, 1395, type III secret
ionタンパク質, type III secretionタンパク質 例えば
InvA [Salmonella typhimurium] gi|476819|pir||A4288
8 (686アミノ酸のうち64%一致)に類似 SEQ ID NO: - ： -0.352577, 98, type III secretion
タンパク質,type III secretionタンパク質 例えばinva
sion タンパク質 [Salmonella enterica] gi|1236845|g
b|aaC45041.1| (355アミノ酸のうち37%一致)に類似 SEQ ID NO: 1552： -0.029639, 389, type III secreti
on タンパク質, type III secretionタンパク質 例えば
InvG [Salmonella typhimurium] gi|1170574|sp|P35672
|INVG#SALTY (558アミノ酸のうち53%一致)に類似 SEQ ID NO: - , 0.760046, 439, type III secretion s
ystemの転写調節因子,転写調節因子 例えばinvF [Salmo
nella typhimurium] gi|729852|sp|P39437|INVF#SALTY
(200アミノ酸のうち40%一致)に類似 SEQ ID NO: 690： -0.029412, 52, 新規, GTGスタート SEQ ID NO: 691： -0.113448, 410, 新規, GTGスタート SEQ ID NO: 692： 0.817973, 218, 新規, ハイポセティ
カルタンパク質 例えば[Methanobacterium thermoautot
rophicum] gi|7482365|pir||D69031 (100アミノ酸のう
ち32%一致)に類似 SEQ ID NO: 693： -0.541477, 177, 推定 トランスポー
ター, ハイポセティカルタンパク質 [プラスミド pNZ40
00] gi|5123516|gb|aaD40355.1| (の185アミノ酸うち31
%一致) に類似;推定 low-affinity inorganic phosphat
e トランスポーター [Mycobacterium tuberculosis] gi
|7387993|sp|O06411|PIT#MYCTU (212アミノ酸のうち26%
一致)に類似(低い) SEQ ID NO: 694： -0.540244, 83, ハイポセティカルリ
ポタンパク質, ハイポセティカルタンパク質 例えば[プ
ラスミド pNZ4000] gi|5123517|gb|aaD40356.1|(209ア
ミノ酸のうち25%一致)に類似 SEQ ID NO: 695： -0.645115, 697, 推定 ABCトランス
ポーター ATP-結合subunit, ABCトランスポーターATP-
結合 subunit 例えばcation ABCトランスポーター(ATP-
結合 タンパク質) homolog ykoD [Bacillus subtilis]
gi|7445788|pir||H69858 (201アミノ酸のうち32%一致)
に類似 SEQ ID NO: 696： -0.096774 311 推定 ABC-トランス
ポーター ATP-結合subunit, ABC-トランスポーター ATP
-結合 subunit 例えばPotA homolog [Agrobacterium rh
izogenes プラスミド pRi1724] gi|8918682|dbj|Baa977
47.1| (223アミノ酸のうち35%一致); [プラスミド pNZ4
000] gi|5123519|gb|aaD40358.1| (211アミノ酸のうち3
0%一致)に類似 SEQ ID NO: 697： 0.076712, 74, 新規, YGGC#ECOLI gi
|1789296 (233アミノ酸のうち83%一致)に類似, しかしC
-末端は異なる; キナーゼ-様タンパク質 FrcK [Sinorhi
zobium meliloti] dad|AF196574-5|aaG28501.1 (190ア
ミノ酸のうち38%一致) に類似, GTGスタート SEQ ID NO: 698： -0.44881, 85, 新規 (ハイポセティ
カルリポタンパク質) SEQ ID NO: 699： -0.246237, 94, インテグラーゼ, イ
ンテグラーゼ 例えば[prophage P4] gi|6179516|emb|CA
B59974.1| (414アミノ酸のうち55%一致)に類似 SEQ ID NO: 700： -0.042222, 91, 新規,ハイポセティ
カルタンパク質 例えばL0015 [Escherichia coli O157:
H7 strainEDL933]] gi|4808945|gb|aaD30027.1|AF11917
0#2のC-末端部分(206アミノ酸のうち88%一致)に類似, G
TGスタート, probably disrupted SEQ ID NO: 701： -0.378351, 98, 新規, ハイポセティ
カルタンパク質 例えばL0013 [Escherichia coli O157:
H7 strain EDL933] gi|3414881|gb|aaC31492.1|の部分
(44アミノ酸のうち100%一致)に類似, GTGスタート, pro
bably disrupted SEQ ID NO: 702： -0.572727, 177, 新規, ハイポセテ
ィカルタンパク質 例えばORF29 [Escherichia coli プ
ラスミド pB171] gi|6009405|dbj|Baa84864.1| (204ア
ミノ酸のうち39%一致)に類似 SEQ ID NO: 703： -0.159444, 181, 新規, ハイポセテ
ィカルタンパク質 例えばORF30 [Escherichia coli プ
ラスミド pB171] gi|6009406|dbj|Baa84865.1| (115ア
ミノ酸のうち80%一致)に類似 SEQ ID NO: 704： 0.131638, 178, 新規, ハイポセティ
カルタンパク質 例えばORF31 [Escherichia coli プラ
スミド pB171] gi|6009427|dbj|Baa84886.1| (468アミ
ノ酸のうち63%一致)に類似 SEQ ID NO: 705： -0.321053, 172, 新規, ハイポセテ
ィカルタンパク質 [Salmonella choleraesuis] gi|7467
227|pir||T28668 (261アミノ酸のうち43%一致)に類似 SEQ ID NO: 706： -0.725, 97, 推定 virulence-relate
d膜タンパク質, virulence-related膜タンパク質 例え
ばpagC [Salmonella typhimurium] gi|129558|sp|P2398
8|PAGC#SALTY (171アミノ酸のうち45%一致)に類似 SEQ ID NO: 707： -0.170161, 125, 新規 SEQ ID NO: 708： -1.030769, 66, 新規, ハイポセティ
カルタンパク質 例えばFhaB [Neisseria meningitidis]
gi|6900333|emb|CAB71945.1| (48アミノ酸のうち37%一
致) に類似(低い), GTGスタート SEQ ID NO: 709： 0.1, 99, 新規, L0028 [Escherichia
coli O157:H7 strain EDL933] gi|3414896|gb|aaC3150
7.1|と同じ; ハイポセティカルタンパク質 例えば[Esch
erichia coli] gi|3249026|gb|aaC69313.1| (203アミノ
酸のうち99%一致)に類似 SEQ ID NO: 710： -0.514201, 170, 新規, L0029 [Esch
erichia coli O157:H7 strain EDL933] gi|3414897|gb|
aaC31508.1|と同じ; rOrf10 [Escherichia coli]gi|286
5295|gb|aaC38388.1| (119アミノ酸のうち78%一致)に類
似 SEQ ID NO: 711： -0.516312, 142, 新規, L0030 [Esch
erichia coli O157:H7 strain EDL933] gi|3414898|gb|
aaC31509.1|と同じ; Orf18 [Escherichia coli]gi|2865
294|gb|aaC38387.1| (159アミノ酸のうち74%一致)に類
似 SEQ ID NO: 712： -0.221687, 167, type III secretio
n system SepQタンパク質, L0031 [Escherichia coli O
157:H7 strain EDL933]; gi|3414899|gb|aaC31510.1|と
同じ; SepQ [Escherichia coli strain E2348/69] gi|2
865293|gb|aaC38386.1| (305アミノ酸のうち93%一致)
に類似 SEQ ID NO: 713： -0.647059, 86, 新規, Orf16 [Esche
richia coli strain E2348/69] gi|2865292|gb|aaC3838
5.1| (138アミノ酸のうち97%一致); L0032 [Escherichi
a coli O157:H7 strain EDL933] gi|3414900|gb|aaC315
11.1| (91アミノ酸のうち100%一致)に類似 SEQ ID NO: 714： -0.245946, 149, 新規, L0033 [Esch
erichia coli O157:H7 strain EDL933] gi|3414901|gb|
aaC31512.1|と同じ SEQ ID NO: 715： -0.574667, 76, type III secretion
systemタンパク質 EscN, EscN (L00349 [Escherichia
coli O157:H7 strain EDL933] gi|3414902|gb|aaC3151
3.1|と同じ SEQ ID NO: 716： -0.092157, 103, type III secretio
n system EscV タンパク質, EscV (L0035) [Escherichi
a coli O157:H7 strain EDL933] gi|3414903|gb|aaC315
14.1|と同じ SEQ ID NO: 717： -0.296875, 97, 新規, Orf12 [Esche
richia coli strain E2348/69] gi|2865288|gb|aaC3838
1.1|; L0036 [Escherichia coli O157:H7 strainEDL93
3] gi|3414904|gb|aaC31515.1|同じ SEQ ID NO: 718： -0.570466, 194, type III secretio
n system SepZタンパク質, と同じSepZ タンパク質 例
えば[Escherichia coli O157:H7 strain EDL933]gi|341
4905|gb|aaC31516.1| SEQ ID NO: 719： -0.367148, 555, 新規, L0038 [Esch
erichia coli O157:H7 strain EDL933] gi|3414906|gb|
aaC31517.1|と同じ; rOrf8 [Escherichia coli E2348/6
9] gi|2865287|gb|aaC38380.1| (142アミノ酸のうち92%
一致)に類似 SEQ ID NO: 720： -0.356102, 509, type III secretio
n system EscJタンパク質, EscJ [Escherichia coli st
rain E2348/69] gi|2865286|gb|aaC38379.1|; L0039 (E
scJ) [Escherichia coli O157:H7 strain EDL933] gi|3
414907|gb|aaC31518.1|と同じ SEQ ID NO: 721： -0.399319, 442, type III secretio
n system タンパク質epD, SepD (L0040) [Escherichia
coli O157:H7 strain EDL933] gi|3414908|gb|aaC3151
9.1|と同じ; SepD タンパク質 例えば[Escherichia col
i strain E2348/69] gi|886476|emb|Caa90273.1| (151
アミノ酸のうち98%一致)に類似 SEQ ID NO: 722： -0.538854, 158, type III secretio
n system EscCタンパク質, EscC (L0041) [Escherichia
coli O157:H7 strain EDL933] gi|3414909|gb|aaC3152
0.1|と同じ SEQ ID NO: 723： -0.272994, 375, type III secretio
n system CesDタンパク質, CesD (L0042) [Escherichia
coli O157:H7 strain EDL933] gi|3414910|gb|aaC3152
1.1|と同じ SEQ ID NO: 724： -0.223492, 316, 新規, L0043 [Esch
erichia coli O157:H7 strain EDL933] gi|3414911|gb|
aaC31522.1|と同じ; Orf11 [Escherichia coli strain
E2348/69] gi|2865282|gb|aaC38375.1| (137アミノ酸の
うち98%一致)に類似 SEQ ID NO: 725： -0.455469, 129, 新規, L0044 [Esch
erichia coli O157:H7 strain EDL933] gi|3414912|gb|
aaC31523.1|と同じ; Orf10 [Escherichia coli strain
E2348/69] gi|2865281|gb|aaC38374.1| (123アミノ酸の
うち98%一致)に類似 SEQ ID NO: 726： -0.330216, 140, 新規, L0045 [Esch
erichia coli O157:H7 strain EDL933] gi|3414913|gb|
aaC31524.1|と同じ; rOrf3 [Escherichia coli strain
E2348/69] gi|2865280|gb|aaC38373.1|(152アミノ酸の
うち98%一致)に類似 SEQ ID NO: 727： -0.154301, 187, type III secretio
n system EscUタンパク質, EscU (L0046) [Escherichia
coli O157:H7 strain EDL933] gi|3414914|gb|aaC3152
5.1|と同じ SEQ ID NO: 728： -0.764198, 82, type III secretion
system EscT タンパク質, EscT (L0047) [Escherichia
coli O157:H7 strain EDL933] gi|3414915|gb|aaC3152
6.1|と同じ SEQ ID NO: 729： -0.1374, 501, type III secretion
system EscSタンパク質,EscS (L0048) [Escherichia co
li O157:H7 strain EDL933] gi|3414916|gb|aaC31527.1
|と同じ SEQ ID NO: 730： -0.500827, 122, type III secretio
n system EscR タンパク質, EscR (L0049) [Escherichi
a coli O157:H7 strain EDL933] gi|3414917|gb|aaC315
28.1|と同じ SEQ ID NO: 731： -0.213291, 159, 新規, L0050 [Esch
erichia coli O157:H7 strain EDL933] gi|3414918|gb|
aaC31529.1|と同じ; Orf5 [Escherichia coli strain E
2348/69] gi|2865275|gb|aaC38368.1| (231アミノ酸の
うち98%一致)に類似 SEQ ID NO: 732： -0.205065, 692, 新規, L0051 [Esch
erichia coli O157:H7 strain EDL933] gi|3414919|gb|
aaC31530.1|と同じOrf4 [Escherichia coli strain E23
48/69] gi|2865274|gb|aaC38367.1| (199アミノ酸のう
ち99%一致)に類似 SEQ ID NO: 733： -0.131141, 457, 新規, Orf3 [Esche
richia coli E2348/69]gi|2865273|gb|aaC38366.1|; L0
052 [Escherichia coli O157:H7 strain EDL933] gi|34
14920|gb|aaC31531.1|と同じ SEQ ID NO: 734： -0.277807, 375, 新規, Orf2 [Esche
richia coli strain E2348/69] gi|2865272|gb|aaC3836
5.1| (72アミノ酸のうち98%一致); L0053 [Escherichia
coli O157:H7 strain EDL933] gi|3414921|gb|aaC3153
2.1| (72アミノ酸のうち98%一致)に類似 SEQ ID NO: 735： -0.335784, 205, 転写調節因子, L00
54 [Escherichia coli O157:H7 strain EDL933] gi|341
4922|gb|aaC31533.1|と同じ; Orf1 Ler [Escherichia c
oli strain E2348/69] gi|2865271|gb|aa C38364.1| (1
29アミノ酸のうち99%一致)に類似 SEQ ID NO: 736： -0.142069, 146, 新規 SEQ ID NO: 737： -0.199169, 362, secreted effector
タンパク質, L0055 [Escherichia coli O157:H7 strai
n EDL933] gi|3414923|gb|aaC31534.1|と同じ; rOrf2 E
spG [Escherichia coli strain E2348/69] gi|2865270|
gb|aaC38363.1| (398アミノ酸のうち97%一致)に類似 SEQ ID NO: 738： -0.374731, 187, 新規, L0056 [Esch
erichia coli O157:H7 strain EDL933] gi|3414924|gb|
aaC31535.1|と同じ； rOrf1 [Escherichia colistrain
E2348/69] gi|2865269|gb|aaC38362.1| (272アミノ酸の
うち99%一致)に類似 SEQ ID NO: 739： -0.368977, 304, 新規, TTGスタート SEQ ID NO: 740： -0.53815, 174, 新規 SEQ ID NO: 741： -0.097015, 68, 新規, ハイポセティ
カルタンパク質 例えばNMA0565 [Neisseria meningitid
is] gi|7379302|emb|CAB83857.1 (118アミノ酸のうち35
%一致)に類似 SEQ ID NO: 742： -0.458602, 187, 新規 SEQ ID NO: 743： -0.278645, 680, 推定 転写調節因
子, 転写調節因子 例えばCom タンパク質 (Momの転写調
節因子) [Bacteriophage Mu] gi|7388376|sp|Q53979|VC
OM#SHIDY(57アミノ酸のうち46%一致)に類似 SEQ ID NO: 744： 0.096667, 61, 推定 DNA modificati
onタンパク質, DNA modificationタンパク質 例えばMom
タンパク質 [Bacteriophage Mu] gi|138782|sp|P06018
|VMOM#BPMU (245アミノ酸のうち76%一致)に類似, GTGス
タート SEQ ID NO: 745： -0.679012, 82, sorbose-permease I
ID component(PTS system), sorbose-permease IID com
ponents 例えば[Klebsiella pneumoniae] gi|548634|sp
|P37083|PTRD#KLEPN (64アミノ酸のうち92%一致)に類
似, interrupted byphage-insertion SEQ ID NO: 746： -0.529126, 104, sorbose-permease
IIC component (PTS system), sorbose-permease IIC c
omponents 例えば[Klebsiella pneumoniae] gi|548633|
sp|P37082|PTRC#KLEPN (265アミノ酸のうち92%一致)に
類似 SEQ ID NO: 747： -0.937879, 67, sorbose-permease I
IB component (PTS system), sorbose-permease IIB co
mponents 例えば[Klebsiella pneumoniae] gi|1142714|
gb|aaB04152.1| (162アミノ酸のうち46%一致)に類似 SEQ ID NO: 748： -0.563673, 246, 推定 sorbose-perm
ease IIA component (PTS system), sorbose-permease
IIA components, 例えば[Klebsiella pneumoniae] gi|5
48631|sp|P37080|PTRA#KLEPN (135アミノ酸のうち71%一
致)に類似 SEQ ID NO: 749： -0.055385, 66, sorbitol-6-phospha
te 2-dehydrogenase, sorbitol-6-phosphate 2-dehydro
genases 例えば[Klebsiella pneumoniae] gi|548951|sp
|P37079|SORD#KLEPN (268アミノ酸のうち86%一致)に類
似 SEQ ID NO: 750： 0.997359, 266, 推定 sorbitol oper
on調節因子 (アクチベーター), sorbitol operon調節因
子 (SorC family) 例えば[Klebsiella pneumoniae] gi|
548950|sp|P37078|SORC#KLEPN (315アミノ酸のうち86%
一致)に類似 SEQ ID NO: 751： -0.115244, 165, 推定 調節タンパク
質, 調節タンパク質 例えばaerobic respiration contr
olタンパク質 [Zymomonas mobilis] gi|4511977|gb|aaD
21537.1| (230アミノ酸のうち39%一致)に類似 SEQ ID NO: 752： 0.19037, 136, 推定 sugar キナー
ゼ, sugar キナーゼ 例えばフルクトキナーゼ homolog
ydjE [Bacillus subtilis] gi|3915420|sp|O34768|YDJE
#BACSU (326アミノ酸のうち24%一致)に類似 SEQ ID NO: 753： -0.159702, 269, 推定 aldolase, al
dolases 例えばfructose-bisphosphate aldolase (EC
4.1.2.13) Fbaa [Bacillus subtilis] gi|543796|sp|P1
3243|ALF1#BACSU (286アミノ酸のうち41%一致)に類似 SEQ ID NO: 754： -0.218413, 316, 新規, ハイポセテ
ィカルタンパク質 ydaE [Bacillus subtilis] gi|74749
28|pir||E69768の部分(51アミノ酸のうち35%一致)に類
似(低い) SEQ ID NO: 1322： 0.197872, 236, 推定 carbohydrate
結合タンパク質, carbohydrate結合タンパク質 例えばo
f bifunctional carbohydrate 結合および輸送タンパク
質 [Streptomyces coelicolor A3(2)] gi|6714794|emb|
CAB66286.1|のC-末端部分 (304アミノ酸のうち35%一
致); ribose ABCトランスポーター (ribose-結合タンパ
ク質) rbsB [Bacillus subtilis] gi|6174949|sp|P3694
9|RBSB#BACSU(261アミノ酸のうち36%一致)に類似 SEQ ID NO: 1323： -0.163964, 334, 推定 carbohydrat
e ABC トランスポーター(permease), carbohydrate ABC
トランスポーター (permease) 例えばribose ABCトラン
スポーター (permease) rbsC [Bacillus subtilis] gi|
7446897|pir||B69690 (317アミノ酸のうち43%一致)に類
似 SEQ ID NO: 1324： 0.066434, 287, 推定 sugar ABCト
ランスポーター, ATP-結合タンパク質, sugar ABCトラ
ンスポーター, ATP-結合タンパク質 例えばriboseABCト
ランスポーター (ATP-結合タンパク質) rbsA [Bacillus
subtilis] gi|7404442|sp|P36947|RBSA#BACSU (489ア
ミノ酸のうち45%一致)に類似 SEQ ID NO: 1325： -0.440969, 228, 推定 histidineタ
ンパク質キナーゼ, histidineタンパク質キナーゼ 例え
ばhistidineタンパク質キナーゼ-response調節因子 hyb
ridタンパク質CvgSY [Pseudomonas syringae pv. syrin
gae] gi|5019771|gb|aaD37857.1|AF133263#2 (364アミ
ノ酸のうち43%一致)に類似 SEQ ID NO: 1326： -0.003195, 314, 推定 transposas
e, transposase homologA [Helicobacter pylori] gi|2
114470|gb|aaD11513.1 (137アミノ酸のうち60%一致)に
類似 SEQ ID NO: 1327： 1.026235, 325, 推定 transposase,
B1432#ECOLI gi|1787702 (402アミノ酸のうち96%一
致); transposases 例えばORFB [Xylella fastidiosa]
gi|9105393|gb|aaF83346.1|AE003901#9 (321アミノ酸の
うち38%一致)に類似 SEQ ID NO: 1328： -0.04664, 507, 推定 インテグラー
ゼ, インテグラーゼ 例えばインテグラーゼ [Bacteriop
hage TPW22] gi|6465906|gb|aaF12706.1|AF066865#4 (3
42アミノ酸のうち23%一致) に類似(低い) SEQ ID NO: - ： -0.010053, 757, transposase (inser
tion sequence IS629),gi|7444868|pir||T00241と同じ SEQ ID NO: 1620： -0.25035, 144, transposase (inse
rtion sequence IS629),[Escherichia coli プラスミド
pO157] gi|7443862|pir||T00240 と同じ SEQ ID NO: 1621： -0.587696, 383, 新規 SEQ ID NO: 1310： -0.455932, 650, 新規, TTGスター
ト SEQ ID NO: 1311： -0.965741, 109, 新規, TTGスター
ト SEQ ID NO: 1312： -0.397973, 297, 新規, ハイポセテ
ィカルタンパク質 [Staphylococcus aureus] 例えばgi|
7594765|dbj|Baa94663.1| (143アミノ酸のうち30%一
致); ハイポセティカルタンパク質 [Neisseria meningi
tidis] gi|5051461|emb|CAB44981.1| (140アミノ酸のう
ち28%一致)に類似(低い) SEQ ID NO: 1313： -0.511702, 95, 推定 resolvase, r
esolvases 例えばresolvase [Escherichia coli transp
oson Tn2501] gi|135944|sp|P05823|TNP0#ECOLI(179ア
ミノ酸のうち45%一致)に類似

【００２９】１２）その他のタンパク質配列番号： 疎水性, アミノ酸の数, 機能等の特性 SEQ ID NO: 1314： 0.037273, 111, 推定 transposase,
transposases 例えば[Escherichia coli Tn5] gi|6229
48|gb|aaB60064.1|のC-末端部分(292アミノ酸のうち32%
一致)に類似, may be disrupted SEQ ID NO: 1315： -0.213793, 59, 新規, KfaE タンパ
ク質 [Escherichia coli] gi|628752|pir||S45104の部
分(52アミノ酸のうち55%一致)に類似 SEQ ID NO: 1316： -0.256129, 156, 推定 enterotoxi
n, ShET2 enterotoxin [Shigella flexneri] gi|110975
4|emb|Caa90938.1| (539アミノ酸のうち38%一致)に類
似; ハイポセティカルタンパク質 例えばankyri様調節
タンパク質 [Escherichia coli] gi|418526|sp|P23325|
ARP#ECOLIの部分(172アミノ酸のうち28%一致)に類似(低
い) SEQ ID NO: 1317： -0.050262, 192, 新規, sBタンパク
質 例えば[insertion element iso-IS1N] gi|124919|sp
|P03832|ISBN#SHIDY (49アミノ酸のうち69%一致)に類
似, TTGスタート SEQ ID NO: 1318： -0.438356, 439, 新規, ハイポセテ
ィカルタンパク質 [Salmonella typhimurium] gi|69603
67|gb|aaF33527.1| (306アミノ酸のうち63%一致)に類似 SEQ ID NO: 1319： -0.524125, 258, 新規 SEQ ID NO: 1320： -0.435714, 155, 新規, ハイポセテ
ィカルタンパク質 in insertion elements 例えば[IS63
0] gi|140943|sp|P16943|YIS5#SHISO (282アミノ酸のう
ち88%一致)に類似 SEQ ID NO: 1014： -0.510181, 276, 推定 adherence f
actor, adherence factors 例えばEfa1 [Escherichia
coli O111:H- strain E45035] gi|6013469|gb|aaD4922
9.2|AF159462#1のN-末端部分(1-433/3223アミノ酸) (43
3アミノ酸のうち99%一致)に類似, probably interrupte
d by frameshift SEQ ID NO: 1015： -0.496819, 284, 推定 DNA-結合タ
ンパク質, 推定 DNA-結合タンパク質 [Neisseria menin
gitidis] gi|7379301|emb|CAB83856.1 (101アミノ酸の
うち47%一致)に類似 SEQ ID NO: 1016： -0.412037, 109, 新規 SEQ ID NO: 1017： -0.505722, 368, 推定 転写調節因
子, N-末端部分が転写調節因子 例えばBamH I control
element [Bacillus amyloliquefaciens] gi|116073|sp|
P23939|CEBA#BACAM (68アミノ酸のうち47%一致) に類似 SEQ ID NO: 1018： -0.409362, 236, インテグラーゼ,
インテグラーゼ 例えば[prophage P4] gi|732036|sp|P3
9347|INTB#ECOLI (236アミノ酸のうち74%一致)に類似 SEQ ID NO: 1019： -0.205818, 551, 新規 SEQ ID NO: 1020： -0.198657, 1118, 新規, ハイポセ
ティカルタンパク質 例えばYjH [Escherichia coli] gi
|7404491|sp|P39371|YJHT#ECOLIの部分 (82アミノ酸の
うち95%一致)に類似, TTGスタート SEQ ID NO: 1021： -0.398339, 2105, 新規 SEQ ID NO: 1022： -0.508378, 944, 新規, 推定 perip
lasmicタンパク質 [Campylobacterjejuni] gi|6968066|
emb|CAB75235.1| (173アミノ酸のうち26%一致)に類似
(低い) SEQ ID NO: 1023： -0.482301, 1645, 新規(推定 膜タ
ンパク質), myosin heavychains 例えば[Cyprinus carp
io] gi|2351223|dbj|Baa22069.1|の部分 (292アミノ酸
のうち19%一致) に類似(低い) SEQ ID NO: 1024： -0.359727, 2114, 新規, YjiT [Esc
herichia coli] gi|732099|sp|P39391|YJIT#ECOLIの部
分 (239アミノ酸のうち27%一致) に類似(低い), GTGス
タート SEQ ID NO: 1025： -0.345738, 705, 新規, N-末端部分
が推定 RNA helicase [Deinococcus radiodurans (stra
in R1)] gi|7473663|pir||B75633のN-末端部分 (291ア
ミノ酸のうち29%一致)に類似; 中心部分がハイポセティ
カルYjiV タンパク質 [Escherichia coli] gi|2851665|
sp|P39393|YJIV#ECOLI (491アミノ酸のうち28%一致); M
crDタンパク質 [Escherichia coli] gi|2851619|sp|P27
301|MCRD#ECOLIの部分 (131アミノ酸のうち39%一致)に
類似 SEQ ID NO: 1026： 0.04, 61, 推定 ATP-依存性helicas
e, 推定 ATP-依存性helicases 例えば[Halobacterium s
p. (strain NRC-1) プラスミド pNRC100] gi|7484100|p
ir||T08316 (597アミノ酸のうち26%一致)に類似 SEQ ID NO: 1027： -0.514474, 77, 新規, ハイポセテ
ィカルタンパク質 例えばH1130 [Halobacterium sp. (s
train NRC-1) プラスミドpNRC100] gi|7484076|pir||T0
8313 (508アミノ酸のうち25%一致); possible restrict
ion /modificationenzyme [Campylobacter jejuni] gi|
6968147|emb|CAB72964.1| (414アミノ酸のうち24%一致)
に類似 SEQ ID NO: 1028： -0.40375, 81, 推定 RNA helicase,
推定RNA helicases 例えば[Deinococcus radiodurans
(strain R1)] gi|7473663|pir||B75633 (78-396アミノ
酸) (318アミノ酸のうち31%一致); (994-1708アミノ酸)
(714アミノ酸のうち23%一致) に類似 SEQ ID NO: 1468： -0.351742, 1580, 推定 DNA helica
se, DNA helicases 例えば推定 DNA helicase H91#ORF5
29 [Mycoplasma pneumoniae] gi|2495150|sp|P75438|YH
91#MYCPN (455アミノ酸のうち24%一致); helicase IV
[Escherichia coli] gi|146328|gb|aaA23952.1| (513ア
ミノ酸のうち23%一致)に類似 SEQ ID NO: 1469： 0.14127, 64, 新規, TTGスタート SEQ ID NO: 1470： -0.245455, 67, 新規, 推定 膜タン
パク質 b1978 [Escherichia coli K-12] gi|1736642|db
j|Baa15799.1|のN-末端部分 (46アミノ酸のうち58%一
致)に類似 SEQ ID NO: 1546： -0.622994, 736, 新規 SEQ ID NO: - ： -0.059091, 89, 新規 SEQ ID NO: 1592： -0.298976, 294, 新規, ハイポセテ
ィカルタンパク質 例えばjhp0462 [Helicobacter pylor
i (strain J99)] gi|7464730|pir||C71929 N-末端部分
(269アミノ酸のうち48%一致); jhp0572 [Helicobacter
pylori (strainJ99)] gi|7464757|pir||H71914 (282ア
ミノ酸のうち31%一致)に類似 SEQ ID NO: 1593： -0.494832, 388, 新規, ハイポセテ
ィカルタンパク質 例えばjhp0462 [Helicobacter pylor
i (strain J99)] gi|7464730|pir||C71929のC-末端部分
(423アミノ酸のうち42%一致); HP0513 [Helicobacter
pylori (strain26695)] gi|7464291|pir||A64584 (423
アミノ酸のうち44%一致)に類似 SEQ ID NO: 1381： -0.367123, 585, type I restricti
on modification enzymeS subunit, type I restrictio
n-modification enzyme S subunits 例えば[Citrobacte
r freundii] pir|S06097| (584アミノ酸のうち54%一致)
に類似 SEQ ID NO: 1382： -0.413184, 494, type I restricti
on modification enzymeM subunit, type I restrictio
n modification enzyme M subunits 例えば[EcoA syste
m] gi|421016|pir||A47200 (489アミノ酸のうち98%一
致)に類似 SEQ ID NO: 1383： -0.505062, 811, type I restricti
on-modification enzymeR subunit, type I restrictio
n-modification enzyme R subunits 例えば[EcoA] gi|2
121113|pir||I41291 (810アミノ酸のうち99%一致)に類
似 SEQ ID NO: 1384： -0.614894, 95, 新規, ハイポセテ
ィカルタンパク質 例えば[Helicobacter pylori] gi|74
64531|pir||E64694のN-末端部分 (87アミノ酸のうち36%
一致)に類似 SEQ ID NO: 1385： -0.442477, 453, 新規, ハイポセテ
ィカルタンパク質 例えば[Streptomyces coelicolor A3
(2)] gi|7479715|pir||T35601 (379アミノ酸のうち22%
一致) に類似(低い), TTGスタート SEQ ID NO: 1689： -0.487222, 181, 新規,

【００３０】１）機能不明なタンパク質：これらのタン
パク質またはポリペプチドは、配列表： SEQ ID NO: 163, SEQ ID NO: 164, SEQ ID NO: 165, SE
Q ID NO: 166, SEQ ID NO: 167, SEQ ID NO: 168, SEQ
ID NO: 169, SEQ ID NO: 170, SEQ ID NO: 171,SEQ ID
NO: 172, SEQ ID NO: 173, SEQ ID NO: 174, SEQ ID N
O: 175, SEQ ID NO: 176, SEQ ID NO: 177, SEQ ID NO:
178, SEQ ID NO: 179, SEQ ID NO: 180,SEQ ID NO: 18
1, SEQ ID NO: 182, SEQ ID NO: 183, SEQ ID NO: 184,
SEQ ID NO: 185, SEQ ID NO: 186, SEQ ID NO: 187, S
EQ ID NO: 188, SEQ ID NO: 189,SEQ ID NO: 190, SEQ
ID NO: 191, SEQ ID NO: 192, SEQ ID NO: 193, SEQ ID
NO: 194, SEQ ID NO: 195, SEQ ID NO: 196, SEQ ID N
O: 197, SEQ ID NO: 198,SEQ ID NO: 199, SEQ ID NO:
200, SEQ ID NO: 201, SEQ ID NO: 202, SEQ ID NO: 20
3, SEQ ID NO: 204, SEQ ID NO: 205, SEQ ID NO: 206,
SEQ ID NO: 207,SEQ ID NO: 208, SEQ ID NO: 209, SE
Q ID NO: 210, SEQ ID NO: 211, SEQ ID NO: 212, SEQ
ID NO: 213, SEQ ID NO: 214, SEQ ID NO: 215, SEQ ID
NO: 216,SEQ ID NO: 217, SEQ ID NO: 218, SEQ ID N
O: 219, SEQ ID NO: 220, SEQ ID NO: 221, SEQ ID NO:
222, SEQ ID NO: 223, SEQ ID NO: 224, SEQ ID NO: 2
25,SEQ ID NO: 226, SEQ ID NO: 227, SEQ ID NO: 228,
SEQ ID NO: 229, SEQ ID NO: 230, SEQ ID NO: 231, S
EQ ID NO: 232, SEQ ID NO: 233, SEQ ID NO: 234,SEQ
ID NO: 235, SEQ ID NO: 236, SEQ ID NO: 237, SEQ ID
NO: 238, SEQ ID NO: 239, SEQ ID NO: 240, SEQ ID N
O: 241, SEQ ID NO: 242, SEQ ID NO: 243,SEQ ID NO:
485, SEQ ID NO: 486, SEQ ID NO: 487, SEQ ID NO: 48
8, SEQ ID NO: 489, SEQ ID NO: 490, SEQ ID NO: 491,
SEQ ID NO: 492, SEQ ID NO: 493,SEQ ID NO: 494, SE
Q ID NO: 495, SEQ ID NO: 496, SEQ ID NO: 497, SEQ
ID NO: 498, SEQ ID NO: 499, SEQ ID NO: 500, SEQ ID
NO: 501, SEQ ID NO: 502,SEQ ID NO: 503, SEQ ID N
O: 504, SEQ ID NO: 505, SEQ ID NO: 506, SEQ ID NO:
507, SEQ ID NO: 508, SEQ ID NO: 509, SEQ ID NO: 5
10, SEQ ID NO: 511,SEQ ID NO: 512, SEQ ID NO: 513,
SEQ ID NO: 514, SEQ ID NO: 515, SEQ ID NO: 516, S
EQ ID NO: 517, SEQ ID NO: 518, SEQ ID NO: 519, SEQ
ID NO: 520,SEQ ID NO: 521, SEQ ID NO: 522, SEQ ID
NO: 523, SEQ ID NO: 524, SEQ ID NO: 525, SEQ ID N
O: 526, SEQ ID NO: 527, SEQ ID NO: 528, SEQ ID NO:
529,SEQ ID NO: 530, SEQ ID NO: 531, SEQ ID NO: 53
2, SEQ ID NO: 533, SEQ ID NO: 534, SEQ ID NO: 535,
SEQ ID NO: 536, SEQ ID NO: 537, SEQ ID NO: 538,SE
Q ID NO: 539, SEQ ID NO: 540, SEQ ID NO: 541, SEQ
ID NO: 542, SEQ ID NO: 543, SEQ ID NO: 544, SEQ ID
NO: 545, SEQ ID NO: 546, SEQ ID NO: 547,SEQ ID N
O: 548, SEQ ID NO: 549, SEQ ID NO: 550, SEQ ID NO:
551, SEQ ID NO: 552, SEQ ID NO: 553, SEQ ID NO: 6
31, SEQ ID NO: 632, SEQ ID NO: 633,SEQ ID NO: 634,
SEQ ID NO: 635, SEQ ID NO: 636, SEQ ID NO: 637, S
EQ ID NO: 638, SEQ ID NO: 639, SEQ ID NO: 640, SEQ
ID NO: 641, SEQ ID NO: 642,SEQ ID NO: 643, SEQ ID
NO: 644, SEQ ID NO: 928, SEQ ID NO: 929, SEQ ID N
O: 930, SEQ ID NO: 931, SEQ ID NO: 932, SEQ ID NO:
933, SEQ ID NO: 934,SEQ ID NO: 935, SEQ ID NO: 93
6, SEQ ID NO: 937, SEQ ID NO: 938, SEQ ID NO: 939,
SEQ ID NO: 940, SEQ ID NO: 941, SEQ ID NO: 942, S
EQ ID NO: 943,SEQ ID NO: 944, SEQ ID NO: 945, SEQ
ID NO: 946, SEQ ID NO: 979, SEQ ID NO: 980, SEQ ID
NO: 981, SEQ ID NO: 982, SEQ ID NO: 983, SEQ ID N
O: 984,SEQ ID NO: 985, SEQ ID NO: 986, SEQ ID NO:
987, SEQ ID NO: 988, SEQ ID NO: 989, SEQ ID NO: 99
0, SEQ ID NO: 991, SEQ ID NO: 992, SEQ ID NO: 993,
SEQ ID NO: 994, SEQ ID NO: 995, SEQ ID NO: 996, SE
Q ID NO: 997, SEQ ID NO: 998, SEQ ID NO: 999, SEQ
ID NO: 1000, SEQ ID NO: 1001, SEQ ID NO: 1002, SEQ
ID NO: 1003, SEQ ID NO: 1004, SEQ ID NO: 1005, SE
Q ID NO: 1006, SEQ ID NO: 1008, SEQ ID NO: 1009, S
EQ ID NO: 1010, SEQ ID NO: 1011, SEQ ID NO: 1012,
SEQ ID NO: 1056, SEQ ID NO: 1057, SEQ ID NO: 1058,
SEQ ID NO: 1059, SEQ ID NO: 1094, SEQ ID NO: 109
5, SEQ ID NO: 1096, SEQ ID NO: 1097, SEQ ID NO: 10
98, SEQ ID NO: 1099, SEQ ID NO: 1100, SEQ ID NO: 1
101,SEQ ID NO: 1102, SEQ ID NO: 1103, SEQ ID NO: 1
104, SEQ ID NO: 1105, SEQID NO: 1106, SEQ ID NO: 1
107, SEQ ID NO: 1108, SEQ ID NO: 1109, SEQ ID NO:
1110, SEQ ID NO: 1111, SEQ ID NO: 1112, SEQ ID NO:
1113, SEQ ID NO: 1114, SEQ ID NO: 1115, SEQ ID N
O: 1116, SEQ ID NO: 1117, SEQ ID NO: 1118SEQ ID N
O: 1119, SEQ ID NO: 1120, SEQ ID NO: 1121, SEQ ID
NO: 1122, SEQID NO: 1123, SEQ ID NO: 1124, SEQ ID
NO: 1125, SEQ ID NO: 1126, SEQ ID NO: 1127, SEQ ID
NO: 1213, SEQ ID NO: 1214, SEQ ID NO: 1215, SEQ I
D NO: 1216, SEQ ID NO: 1217, SEQ ID NO: 1218, SEQ
ID NO: 1219, SEQ ID NO: 1220,SEQ ID NO: 1221, SEQ
ID NO: 1222, SEQ ID NO: 1223, SEQ ID NO: 1224, SEQ
ID NO: 1225, SEQ ID NO: 1226, SEQ ID NO: 1227, SEQ
ID NO: 1228, SEQ IDNO: 1229, SEQ ID NO: 1230, SEQ
ID NO: 1231, SEQ ID NO: 1232, SEQ ID NO:1233, SEQ
ID NO: 1234, SEQ ID NO: 1235, SEQ ID NO: 1236, SE
Q ID NO: 1237, SEQ ID NO: 1238, SEQ ID NO: 1239, S
EQ ID NO: 1275, SEQ ID NO: 1276, SEQ ID NO: 1277,
SEQ ID NO: 1278, SEQ ID NO: 1279, SEQ ID NO: 1280,
SEQ IDNO: 1281, SEQ ID NO: 1282, SEQ ID NO: 1284,
SEQ ID NO: 1285, SEQ ID NO:1286, SEQ ID NO: 1287,
SEQ ID NO: 1303, SEQ ID NO: 1304, SEQ ID NO: 130
5, SEQ ID NO: 1306, SEQ ID NO: 1307, SEQ ID NO: 13
08, SEQ ID NO: 1360, SEQ ID NO: 1361, SEQ ID NO: 1
362, SEQ ID NO: 1363, SEQ ID NO: 1364, SEQ ID NO:
1365, SEQ ID NO: 1387, SEQ ID NO: 1388, SEQ ID NO:
1389, SEQ ID NO: 1390, SEQ ID NO: 1391, SEQ ID N
O: 1392, SEQ ID NO: 1393, SEQ ID NO: 1437, SEQ ID
NO: 1438, SEQ ID NO: 1439, SEQ ID NO: 1440, SEQ ID
NO: 1441,SEQ ID NO: 1442, SEQ ID NO: 1451, SEQ ID
NO: 1452, SEQ ID NO: 1453, SEQID NO: 1454, SEQ ID
NO: 1455, SEQ ID NO: 1456, SEQ ID NO: 1474, SEQ I
D NO: 1475, SEQ ID NO: 1476, SEQ ID NO: 1479, SEQ
ID NO: 1480, SEQ ID NO: 1481, SEQ ID NO: 1482, SEQ
ID NO: 1483, SEQ ID NO: 1484, SEQ ID NO: 1485,SEQ
ID NO: 1486, SEQ ID NO: 1495, SEQ ID NO: 1496, SE
Q ID NO: 1497, SEQID NO: 1498, SEQ ID NO: 1500, SE
Q ID NO: 1502, SEQ ID NO: 1503, SEQ IDNO: 1504, SE
Q ID NO: 1505, SEQ ID NO: 1559, SEQ ID NO: 1560, S
EQ ID NO:1561, SEQ ID NO: 1562, SEQ ID NO: 1577, S
EQ ID NO: 1578, SEQ ID NO: 1579, SEQ ID NO: 1602,
SEQ ID NO: 1606, SEQ ID NO: 1625, SEQ ID NO: 1663,
SEQ ID NO: 1697, SEQ ID NO: 1698, SEQ ID NO: 170
2, およびSEQ ID NO: 1703 からなる群から選択される。これらのタンパク質または
ポリペプチドはＯ１５７：Ｈ７に特異的であるが、決定
されたアミノ酸配列の情報から、全遺伝子データバンク
に登録されているデータと有意なホモロジーが見出され
ず、且つその機能などが不明なものである。しかしなが
ら、表１に示されるように、これらの中には細胞表面タ
ンパク質（膜タンパク質、特に外膜タンパク質（ＯＭ
Ｐ）、リポタンパク質）と予測されるタンパク質および
その遺伝子（または核酸分子）は、抗体作製、ワクチン
組成物およびＯ１５７感染の診断等に有用であり得る。
また、この中にＯ１５７において重要な機能を有する、
例えば物質の輸送および代謝、核酸のプロセッシング、
調節因子並びに病原性に関連するタンパク質が包含され
ている可能性があり、これらはＯ１５７感染の診断およ
び治療に有用となる。

【００３１】２）機能等は不明であるが、他の菌体由来
のものと有意なホモロジーを有するタンパク質：これら
のタンパク質またはポリペプチドは、配列表： SEQ ID NO: 02, SEQ ID NO: 03, SEQ ID NO: 04, SEQ I
D NO: 05,SEQ ID NO: 06, SEQ ID NO: 07, SEQ ID NO:
08, SEQ ID NO: 09, SEQ ID NO: 10, SEQ ID NO: 11,
SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ I
D NO: 15, SEQ IDNO: 16, SEQ ID NO: 17, SEQ ID NO:
18, SEQ ID NO: 19, SEQ ID NO: 20, SEQID NO: 21, SE
Q ID NO: 22, SEQ ID NO: 23, SEQ ID NO: 24, SEQ ID
NO: 25,SEQ ID NO: 26, SEQ ID NO: 27, SEQ ID NO: 2
8, SEQ ID NO: 29, SEQ ID NO: 30, SEQ ID NO: 31,SEQ
ID NO: 32, SEQ ID NO: 245, SEQ ID NO: 246, SEQ I
DNO: 247, SEQ ID NO: 248, SEQ ID NO: 249, SEQ ID N
O: 250, SEQ ID NO: 251,SEQ ID NO: 252, SEQ ID NO:
253, SEQ ID NO: 254, SEQ ID NO: 255, SEQ IDNO: 25
6, SEQ ID NO: 257, SEQ ID NO: 258, SEQ ID NO: 259,
SEQ ID NO: 260,SEQ ID NO: 261, SEQ ID NO: 262, SE
Q ID NO: 263, SEQ ID NO: 264, SEQ IDNO: 265, SEQ I
D NO: 266, SEQ ID NO: 267, SEQ ID NO: 268, SEQ ID
NO: 270,SEQ ID NO: 271, SEQ ID NO: 272, SEQ ID NO:
273, SEQ ID NO: 338, SEQ IDNO: 339, SEQ ID NO: 34
0, SEQ ID NO: 341, SEQ ID NO: 342, SEQ ID NO: 343,
SEQ ID NO: 344, SEQ ID NO: 345, SEQ ID NO: 346, SE
Q ID NO: 347, SEQ IDNO: 348, SEQ ID NO: 349, SEQ I
D NO: 350, SEQ ID NO: 351, SEQ ID NO: 352,SEQ ID N
O: 353, SEQ ID NO: 354, SEQ ID NO: 355, SEQ ID NO:
356, SEQ IDNO: 357, SEQ ID NO: 358, SEQ ID NO: 35
9, SEQ ID NO: 360, SEQ ID NO: 361,SEQ ID NO: 362,
SEQ ID NO: 363, SEQ ID NO: 364, SEQ ID NO: 365, SE
Q IDNO: 366, SEQ ID NO: 367, SEQ ID NO: 368, SEQ I
D NO: 369, SEQ ID NO: 370,SEQ ID NO: 371, SEQ ID N
O: 372, SEQ ID NO: 373, SEQ ID NO: 374, SEQ IDNO:
375, SEQ ID NO: 376, SEQ ID NO: 377, SEQ ID NO: 37
8, SEQ ID NO: 379,SEQ ID NO: 380, SEQ ID NO: 381,
SEQ ID NO: 382, SEQ ID NO: 383, SEQ IDNO: 384, SEQ
ID NO: 385, SEQ ID NO: 386, SEQ ID NO: 387, SEQ I
D NO: 388,SEQ ID NO: 389, SEQ ID NO: 390, SEQ ID N
O: 391, SEQ ID NO: 392, SEQ IDNO: 393, SEQ ID NO:
394, SEQ ID NO: 395, SEQ ID NO: 396, SEQ ID NO: 39
7,SEQ ID NO: 398, SEQ ID NO: 399, SEQ ID NO: 400,
SEQ ID NO: 401, SEQ IDNO: 402, SEQ ID NO: 403, SEQ
ID NO: 404, SEQ ID NO: 405, SEQ ID NO: 406,SEQ ID
NO: 407, SEQ ID NO: 408, SEQ ID NO: 409, SEQ ID N
O: 411, SEQ IDNO: 412, SEQ ID NO: 413, SEQ ID NO:
414, SEQ ID NO: 416, SEQ ID NO: 417,SEQ ID NO: 41
8, SEQ ID NO: 419, SEQ ID NO: 420, SEQ ID NO: 421,
SEQ IDNO: 422, SEQ ID NO: 423, SEQ ID NO: 424, SE
Q ID NO: 425, SEQ ID NO: 426,SEQ ID NO: 427, SEQ I
D NO: 428, SEQ ID NO: 429, SEQ ID NO: 430, SEQ IDN
O: 431, SEQ ID NO: 432, SEQ ID NO: 433, SEQ ID NO:
434, SEQ ID NO: 435,SEQ ID NO: 436, SEQ ID NO: 43
7, SEQ ID NO: 438, SEQ ID NO: 439, SEQ IDNO: 440,
SEQ ID NO: 441, SEQ ID NO: 442, SEQ ID NO: 443, SE
Q ID NO: 444,SEQ ID NO: 445, SEQ ID NO: 446, SEQ I
D NO: 447, SEQ ID NO: 448, SEQ IDNO: 449, SEQ ID N
O: 450, SEQ ID NO: 451, SEQ ID NO: 452, SEQ ID NO:
453,SEQ ID NO: 454, SEQ ID NO: 455, SEQ ID NO: 45
6, SEQ ID NO: 457, SEQ IDNO: 458, SEQ ID NO: 459,
SEQ ID NO: 460, SEQ ID NO: 461, SEQ ID NO: 462,SEQ
ID NO: 463, SEQ ID NO: 464, SEQ ID NO: 465, SEQ I
D NO: 466, SEQ IDNO: 467, SEQ ID NO: 468, SEQ ID N
O: 469, SEQ ID NO: 470, SEQ ID NO: 471,SEQ ID NO:
472, SEQ ID NO: 473, SEQ ID NO: 474, SEQ ID NO: 47
5, SEQ IDNO: 476, SEQ ID NO: 477, SEQ ID NO: 478,
SEQ ID NO: 479, SEQ ID NO: 480,SEQ ID NO: 481, SEQ
ID NO: 482, SEQ ID NO: 483, SEQ ID NO: 645, SEQ I
DNO: 646, SEQ ID NO: 647, SEQ ID NO: 648, SEQ ID N
O: 649, SEQ ID NO: 650,SEQ ID NO: 651, SEQ ID NO:
652, SEQ ID NO: 653, SEQ ID NO: 654, SEQ IDNO: 65
5, SEQ ID NO: 656, SEQ ID NO: 657, SEQ ID NO: 658,
SEQ ID NO: 659,SEQ ID NO: 660, SEQ ID NO: 661, SE
Q ID NO: 662, SEQ ID NO: 663, SEQ IDNO: 664, SEQ I
D NO: 665, SEQ ID NO: 666, SEQ ID NO: 667, SEQ ID
NO: 668,SEQ ID NO: 669, SEQ ID NO: 670, SEQ ID NO:
671, SEQ ID NO: 672, SEQ IDNO: 673, SEQ ID NO: 67
4, SEQ ID NO: 675, SEQ ID NO: 676, SEQ ID NO: 677,
SEQ ID NO: 678, SEQ ID NO: 679, SEQ ID NO: 680, SE
Q ID NO: 681, SEQ IDNO: 682, SEQ ID NO: 683, SEQ I
D NO: 684, SEQ ID NO: 685, SEQ ID NO: 686,SEQ ID N
O: 687, SEQ ID NO: 688, SEQ ID NO: 877, SEQ ID NO:
878, SEQ IDNO: 879, SEQ ID NO: 880, SEQ ID NO: 88
1, SEQ ID NO: 882, SEQ ID NO: 883,SEQ ID NO: 884,
SEQ ID NO: 885, SEQ ID NO: 886, SEQ ID NO: 887, SE
Q IDNO: 888, SEQ ID NO: 889, SEQ ID NO: 890, SEQ I
D NO: 891, SEQ ID NO: 892,SEQ ID NO: 893, SEQ ID N
O: 894, SEQ ID NO: 895, SEQ ID NO: 896, SEQ IDNO:
897, SEQ ID NO: 898, SEQ ID NO: 899, SEQ ID NO: 90
0, SEQ ID NO: 901,SEQ ID NO: 902, SEQ ID NO: 903,
SEQ ID NO: 904, SEQ ID NO: 905, SEQ IDNO: 906, SEQ
ID NO: 907, SEQ ID NO: 908, SEQ ID NO: 909, SEQ I
D NO: 910,SEQ ID NO: 911, SEQ ID NO: 912, SEQ ID N
O: 913, SEQ ID NO: 914, SEQ IDNO: 915, SEQ ID NO:
916, SEQ ID NO: 917, SEQ ID NO: 918, SEQ ID NO: 91
9,SEQ ID NO: 920, SEQ ID NO: 921, SEQ ID NO: 922,
SEQ ID NO: 923, SEQ IDNO: 924, SEQ ID NO: 925, SEQ
ID NO: 926, SEQ ID NO: 947, SEQ ID NO: 947,SEQ ID
NO: 949, SEQ ID NO: 950, SEQ ID NO: 951, SEQ ID N
O: 952, SEQ IDNO: 953, SEQ ID NO: 954, SEQ ID NO:
955, SEQ ID NO: 956, SEQ ID NO: 957,SEQ ID NO: 95
8, SEQ ID NO: 959, SEQ ID NO: 960, SEQ ID NO: 961,
SEQ IDNO: 962, SEQ ID NO: 963, SEQ ID NO: 964, SE
Q ID NO: 965, SEQ ID NO: 966,SEQ ID NO: 967, SEQ I
D NO: 968, SEQ ID NO: 968, SEQ ID NO: 969, SEQ IDN
O: 970, SEQ ID NO: 971, SEQ ID NO: 972, SEQ ID NO:
973, SEQ ID NO: 1026, SEQ ID NO: 1027, SEQ ID NO:
1028, SEQ ID NO: 1375, SEQ ID NO: 1376, SEQ ID N
O: 1377, SEQ ID NO: 1378, SEQ ID NO: 1379, SEQ ID
NO: 1410, SEQ IDNO: 1419, SEQ ID NO: 1420, SEQ ID
NO: 1421, SEQ ID NO: 1422, SEQ ID NO:1423, SEQ ID
NO: 1424, SEQ ID NO: 1425, SEQ ID NO: 1488, SEQ ID
NO: 1517, SEQ ID NO: 1516, SEQ ID NO: 1517, SEQ I
D NO: 1538, SEQ ID NO: 1539, SEQ ID NO: 1550, SEQ
ID NO: 1567, SEQ ID NO: 1568, SEQ ID NO: 1608, SEQ
ID NO: 1609, SEQ ID NO: 1610, SEQ ID NO: 1611, SE
Q ID NO: 1628, SEQ ID NO: 1633, SEQ ID NO: 1634, S
EQ ID NO: 1641, SEQ ID NO: 1642, SEQ ID NO: 1644,
SEQ ID NO: 1645, SEQ ID NO: 1665, SEQ ID NO: 1676,
およびSEQ ID NO:1681 からなる群から選択される。これらのタンパク質または
ポリペプチドはＯ１５７：Ｈ７に特異的であるが、決定
されたアミノ酸配列の情報から、全遺伝子データバンク
に登録されている他由来のタンパク質と有意なホモロジ
ーが見出されたが、その機能などが不明なものである。
しかしながら、表１に示されるように、これらの中には
細胞表面タンパク質（膜タンパク質、特にＯＭＰ、リポ
タンパク質）と予測されるタンパク質およびその遺伝子
（または核酸分子）は、抗体作製、ワクチン組成物およ
びＯ１５７感染の診断等に有用であり得る。また、この
中にＯ１５７において重要な機能を有する、例えば物質
の輸送および代謝、核酸のプロセッシング、調節因子並
びに病原性に関連するタンパク質が包含されている可能
性があり、これらはＯ１５７感染の診断および治療に有
用となる。

【００３２】３）挿入配列（Insertion Sequence; IS）
を含むタンパク質：これらのタンパク質またはポリペプ
チドは、配列表： SEQ ID NO: 133, SEQ ID NO: 134, SEQ ID NO: 135, SE
Q ID NO: 136, SEQ ID NO: 137, SEQ ID NO: 138, SEQ
ID NO: 139, SEQ ID NO: 140, SEQ ID NO: 141,SEQ ID
NO: 142, SEQ ID NO: 143, SEQ ID NO: 144, SEQ ID N
O: 145, SEQ ID NO: 146, SEQ ID NO: 147, SEQ ID NO:
148, SEQ ID NO: 149, SEQ ID NO: 150,SEQ ID NO: 15
1, SEQ ID NO: 152, SEQ ID NO: 153, SEQ ID NO: 154,
SEQ ID NO: 155, SEQ ID NO: 156, SEQ ID NO: 157, S
EQ ID NO: 158, SEQ ID NO: 159,SEQ ID NO: 160, SEQ
ID NO: 161, SEQ ID NO: 162, SEQ ID NO: 279, SEQ ID
NO: 280, SEQ ID NO: 281, SEQ ID NO: 282, SEQ ID N
O: 283, SEQ ID NO: 284,SEQ ID NO: 285, SEQ ID NO:
286, SEQ ID NO: 287, SEQ ID NO: 288, SEQ ID NO: 28
9, SEQ ID NO: 290, SEQ ID NO: 291, SEQ ID NO: 292,
SEQ ID NO: 293,SEQ ID NO: 294, SEQ ID NO: 295, SE
Q ID NO: 296, SEQ ID NO: 297, SEQ ID NO: 298, SEQ
ID NO: 299, SEQ ID NO: 300, SEQ ID NO: 301, SEQ ID
NO: 302,SEQ ID NO: 303, SEQ ID NO: 304, SEQ ID N
O: 305, SEQ ID NO: 306, SEQ ID NO: 307, SEQ ID NO:
308, SEQ ID NO: 309, SEQ ID NO: 310, SEQ ID NO: 3
11,SEQ ID NO: 312, SEQ ID NO: 313, SEQ ID NO: 314,
SEQ ID NO: 315, SEQ ID NO: 316, SEQ ID NO: 317, S
EQ ID NO: 318, SEQ ID NO: 319, SEQ ID NO: 320,SEQ
ID NO: 321, SEQ ID NO: 322, SEQ ID NO: 323, SEQ ID
NO: 324, SEQ ID NO: 325, SEQ ID NO: 326, SEQ ID N
O: 327, SEQ ID NO: 328, SEQ ID NO: 329,SEQ ID NO:
330, SEQ ID NO: 331, SEQ ID NO: 332, SEQ ID NO: 33
3, SEQ ID NO: 334, SEQ ID NO: 335, SEQ ID NO: 336,
SEQ ID NO: 1030, SEQ ID NO: 1031, SEQ ID NO: 103
2, SEQ ID NO: 1033, SEQ ID NO: 1034, SEQ ID NO: 10
35, SEQ ID NO: 1036, SEQ ID NO: 1037, SEQ ID NO: 1
038, SEQ ID NO: 1039, SEQ IDNO: 1040, SEQ ID NO: 1
041, SEQ ID NO: 1042, SEQ ID NO: 1043, SEQ ID NO:1
044, SEQ ID NO: 1045, SEQ ID NO: 1046, SEQ ID NO:
1047, SEQ ID NO: 1048, SEQ ID NO: 1049, SEQ ID NO:
1050, SEQ ID NO: 1051, SEQ ID NO: 1052, SEQ ID N
O: 1053, SEQ ID NO: 1054, およびSEQ ID NO: 1570 からなる群から選択される。これらタンパク質およびそ
の遺伝子（または核酸分子）は、Ｏ１５７感染の検出お
よび診断に有用である。

【００３３】４）ファージに由来のタンパク質：これら
のタンパク質またはポリペプチドは、配列表： SEQ ID NO: 33, SEQ ID NO: 34, SEQ ID NO: 35, SEQ I
D NO: 36, SEQ ID NO: 37, SEQ ID NO: 38, SEQ ID NO:
39, SEQ ID NO: 40, SEQ ID NO: 41, SEQ ID NO: 42,
SEQ ID NO: 43, SEQ ID NO: 44, SEQ ID NO: 45, SEQ I
D NO: 46, SEQ IDNO: 47, SEQ ID NO: 48, SEQ ID NO:
49, SEQ ID NO: 50, SEQ ID NO: 51, SEQID NO: 52, SE
Q ID NO: 53, SEQ ID NO: 54, SEQ ID NO: 55, SEQ ID
NO: 56,SEQ ID NO: 57, SEQ ID NO: 58, SEQ ID NO: 5
9, SEQ ID NO: 60, SEQ ID NO: 61, SEQ ID NO: 62, SE
Q ID NO: 63, SEQ ID NO: 64, SEQ ID NO: 65, SEQ ID
NO: 66, SEQ ID NO: 67, SEQ ID NO: 68, SEQ ID NO: 6
9, SEQ ID NO: 70, SEQ IDNO: 71, SEQ ID NO: 72, SEQ
ID NO: 73, SEQ ID NO: 74, SEQ ID NO: 75, SEQID N
O: 76, SEQ ID NO: 77, SEQ ID NO: 78, SEQ ID NO: 7
9, SEQ ID NO: 80,SEQ ID NO: 81, SEQ ID NO: 82, SEQ
ID NO: 83, SEQ ID NO: 84, SEQ ID NO: 85, SEQ ID N
O: 86, SEQ ID NO: 87, SEQ ID NO: 88, SEQ ID NO: 8
9, SEQ ID NO: 90, SEQ ID NO: 91, SEQ ID NO: 92, SE
Q ID NO: 93, SEQ ID NO: 94, SEQ IDNO: 95, SEQ ID N
O: 96, SEQ ID NO: 97, SEQ ID NO: 98, SEQ ID NO: 9
9, SEQID NO: 100, SEQ ID NO: 101, SEQ ID NO: 102,
SEQ ID NO: 103, SEQ ID NO:104, SEQ ID NO: 105, SEQ
ID NO: 106, SEQ ID NO: 107, SEQ ID NO: 108, SEQID
NO: 109, SEQ ID NO: 110, SEQ ID NO: 111, SEQ ID N
O: 112, SEQ ID NO:113, SEQ ID NO: 114, SEQ ID NO:
115, SEQ ID NO: 116, SEQ ID NO: 117, SEQID NO: 11
8, SEQ ID NO: 119, SEQ ID NO: 120, SEQ ID NO: 121,
SEQ ID NO:122, SEQ ID NO: 123, SEQ ID NO: 124, SE
Q ID NO: 125, SEQ ID NO: 126, SEQID NO: 127, SEQ I
D NO: 128, SEQ ID NO: 129, SEQ ID NO: 130, SEQ ID
NO:131, SEQ ID NO: 555, SEQ ID NO: 556, SEQ ID NO:
557, SEQ ID NO: 558, SEQID NO: 559, SEQ ID NO: 56
0, SEQ ID NO: 561, SEQ ID NO: 562, SEQ ID NO:563,
SEQ ID NO: 564, SEQ ID NO: 565, SEQ ID NO: 566, SE
Q ID NO: 567, SEQID NO: 568, SEQ ID NO: 569, SEQ I
D NO: 570, SEQ ID NO: 571, SEQ ID NO:572, SEQ ID N
O: 573, SEQ ID NO: 574, SEQ ID NO: 575, SEQ ID NO:
576, SEQID NO: 577, SEQ ID NO: 578, SEQ ID NO: 57
9, SEQ ID NO: 580, SEQ ID NO:581, SEQ ID NO: 582,
SEQ ID NO: 583, SEQ ID NO: 584, SEQ ID NO: 585, SE
QID NO: 586, SEQ ID NO: 587, SEQ ID NO: 588, SEQ I
D NO: 589, SEQ ID NO:590, SEQ ID NO: 591, SEQ ID N
O: 592, SEQ ID NO: 593, SEQ ID NO: 594, SEQID NO:
595, SEQ ID NO: 596, SEQ ID NO: 597, SEQ ID NO: 59
8, SEQ ID NO:599, SEQ ID NO: 600, SEQ ID NO: 601,
SEQ ID NO: 602, SEQ ID NO: 603, SEQID NO: 604, SEQ
ID NO: 605, SEQ ID NO: 606, SEQ ID NO: 607, SEQ I
D NO:608, SEQ ID NO: 609, SEQ ID NO: 610, SEQ ID N
O: 611, SEQ ID NO: 612, SEQID NO: 613, SEQ ID NO:
614, SEQ ID NO: 615, SEQ ID NO: 616, SEQ ID NO:61
7, SEQ ID NO: 618, SEQ ID NO: 619, SEQ ID NO: 620,
SEQ ID NO: 621, SEQID NO: 622, SEQ ID NO: 623, SE
Q ID NO: 624, SEQ ID NO: 625, SEQ ID NO:626, SEQ I
D NO: 627, SEQ ID NO: 628, SEQ ID NO: 629, SEQ ID
NO: 756, SEQID NO: 757, SEQ ID NO: 758, SEQ ID NO:
759, SEQ ID NO: 760, SEQ ID NO:761, SEQ ID NO: 76
2, SEQ ID NO: 763, SEQ ID NO: 764, SEQ ID NO: 765,
SEQID NO: 766, SEQ ID NO: 767, SEQ ID NO: 768, SE
Q ID NO: 769, SEQ ID NO:770, SEQ ID NO: 771, SEQ I
D NO: 772, SEQ ID NO: 773, SEQ ID NO: 774, SEQID N
O: 775, SEQ ID NO: 776, SEQ ID NO: 777, SEQ ID NO:
778, SEQ ID NO:779, SEQ ID NO: 780, SEQ ID NO: 78
1, SEQ ID NO: 782, SEQ ID NO: 783, SEQID NO: 784,
SEQ ID NO: 785, SEQ ID NO: 786, SEQ ID NO: 787, SE
Q ID NO:788, SEQ ID NO: 789, SEQ ID NO: 790, SEQ I
D NO: 791, SEQ ID NO: 792, SEQID NO: 793, SEQ ID N
O: 794, SEQ ID NO: 795, SEQ ID NO: 796, SEQ ID NO:
797, SEQ ID NO: 798, SEQ ID NO: 799, SEQ ID NO: 80
0, SEQ ID NO: 801, SEQID NO: 802, SEQ ID NO: 803,
SEQ ID NO: 804, SEQ ID NO: 805, SEQ ID NO:806, SEQ
ID NO: 807, SEQ ID NO: 808, SEQ ID NO: 809, SEQ I
D NO: 810, SEQID NO: 811, SEQ ID NO: 812, SEQ ID N
O: 813, SEQ ID NO: 814, SEQ ID NO:815, SEQ ID NO:
1061, SEQ ID NO: 1062, SEQ ID NO: 1063, SEQ ID NO:
1064,SEQ ID NO: 1065, SEQ ID NO: 1066, SEQ ID NO:
1067, SEQ ID NO: 1068, SEQID NO: 1069, SEQ ID NO:
1070, SEQ ID NO: 1071, SEQ ID NO: 1072, SEQ IDNO:
1073, SEQ ID NO: 1074, SEQ ID NO: 1075, SEQ ID N
O: 1076, SEQ ID NO:1077, SEQ ID NO: 1078, SEQ ID N
O: 1079, SEQ ID NO: 1080, SEQ ID NO: 1081, SEQ ID
NO: 1082, SEQ ID NO: 1083, SEQ ID NO: 1084, SEQ ID
NO: 1085, SEQ ID NO: 1086, SEQ ID NO: 1087, SEQ I
D NO: 1088, SEQ ID NO: 1089, SEQ IDNO: 1090, SEQ I
D NO: 1091, SEQ ID NO: 1092, SEQ ID NO: 1158, SEQ
ID NO:1159, SEQ ID NO: 1160, SEQ ID NO: 1161, SEQ
ID NO: 1162, SEQ ID NO: 1163, SEQ ID NO: 1164, SEQ
ID NO: 1165, SEQ ID NO: 1166, SEQ ID NO: 1167, S
ＥＱ ＩＤ ＮＯ： １１６８， ＳＥＱ ＩＤ Ｎ
Ｏ： １１６９， ＳＥＱ ＩＤ ＮＯ： １１７０，
ＳＥＱ ＩＤ ＮＯ： １１７１， ＳＥＱ ＩＤ
ＮＯ： １１７２， ＳＥＱ ＩＤ ＮＯ： １１７
３， ＳＥＱ ＩＤ ＮＯ： １１７４， ＳＥＱ Ｉ
Ｄ ＮＯ： １１７５， ＳＥＱ ＩＤ ＮＯ： １１
７６， ＳＥＱ ＩＤ ＮＯ： １１７７， ＳＥＱ
ＩＤ ＮＯ： １１７８， ＳＥＱ ＩＤ ＮＯ： １
１７９， ＳＥＱ ＩＤ ＮＯ： １１８０， ＳＥＱ
ＩＤ ＮＯ： １１８１， ＳＥＱ ＩＤ ＮＯ：
１１８２， ＳＥＱ ＩＤ ＮＯ： １１８３， ＳＥ
Ｑ ＩＤ ＮＯ： １１８４，ＳＥＱ ＩＤ ＮＯ：
１１８５， ＳＥＱ ＩＤ ＮＯ： １１８６， ＳＥ
Ｑ ＩＤ ＮＯ： １１８７， ＳＥＱ ＩＤ ＮＯ：
１１８８， ＳＥＱＩＤ ＮＯ： １１８９， ＳＥ
Ｑ ＩＤ ＮＯ： １１９０， ＳＥＱ ＩＤ ＮＯ：
１２５９， ＳＥＱ ＩＤ ＮＯ： １２６０， Ｓ
ＥＱ ＩＤ ＮＯ： １２６１， ＳＥＱ ＩＤ Ｎ
Ｏ： １２６２， ＳＥＱ ＩＤ ＮＯ： １２６３，
ＳＥＱ ＩＤ ＮＯ： １２６４， ＳＥＱ ＩＤ
ＮＯ： １２６５， ＳＥＱ ＩＤ ＮＯ： １２６
６， ＳＥＱ ＩＤ ＮＯ： １２６７， ＳＥＱ Ｉ
Ｄ ＮＯ： １２６８， ＳＥＱ ＩＤ ＮＯ： １２
６９，ＳＥＱ ＩＤ ＮＯ： １２７０， ＳＥＱ Ｉ
Ｄ ＮＯ： １２７１， ＳＥＱ ＩＤ ＮＯ： １２
７２， ＳＥＱ ＩＤ ＮＯ： １２７３， ＳＥＱＩ
Ｄ ＮＯ： １２８９， ＳＥＱ ＩＤ ＮＯ： １２
９０， ＳＥＱ ＩＤ ＮＯ： １２９１， ＳＥＱ
ＩＤ ＮＯ： １２９２， ＳＥＱ ＩＤＮＯ： １２
９３， ＳＥＱ ＩＤ ＮＯ： １２９４， ＳＥＱ
ＩＤ ＮＯ： １２９５， ＳＥＱ ＩＤ ＮＯ： １
２９６， ＳＥＱ ＩＤ ＮＯ：１２９７， ＳＥＱ
ＩＤ ＮＯ： １２ ９８， ＳＥＱ ＩＤ ＮＯ：
１２９９， ＳＥＱ ＩＤ ＮＯ： １３００， ＳＥ
Ｑ ＩＤ ＮＯ： １３０１， ＳＥＱ ＩＤ ＮＯ：
１３３０， ＳＥＱ ＩＤ ＮＯ： １３３１， Ｓ
ＥＱ ＩＤ ＮＯ： １３３２， ＳＥＱ ＩＤ Ｎ
Ｏ： １３３３， ＳＥＱ ＩＤ ＮＯ： １３３４，
ＳＥＱ ＩＤ ＮＯ： １３４９， ＳＥＱ ＩＤ
ＮＯ： １３５０， ＳＥＱ ＩＤ ＮＯ： １３５
１， ＳＥＱ ＩＤ ＮＯ： １３５２， ＳＥＱ Ｉ
Ｄ ＮＯ： １３５３， ＳＥＱ ＩＤ ＮＯ： １３
５４， ＳＥＱ ＩＤ ＮＯ： １３５５， ＳＥＱ
ＩＤ ＮＯ： １３５６， ＳＥＱ ＩＤ ＮＯ： １
３５７， ＳＥＱ ＩＤ ＮＯ： １３５８， ＳＥＱ
ＩＤ ＮＯ： １４４５， ＳＥＱ ＩＤ ＮＯ：
１４４６， ＳＥＱ ＩＤ ＮＯ： １４４６， ＳＥ
Ｑ ＩＤ ＮＯ： １４４７， １４４８， ＳＥＱ
ＩＤ ＮＯ： １４４９， ＳＥＱ ＩＤ ＮＯ：１４
９０， ＳＥＱ ＩＤ ＮＯ： １４９１， ＳＥＱ
ＩＤ ＮＯ： １４９２， ＳＥＱ ＩＤ ＮＯ： １
４９３， ＳＥＱ ＩＤ ＮＯ： １５０９， ＳＥＱ
ＩＤ ＮＯ： １５４１， ＳＥＱ ＩＤ ＮＯ：
１５４２， ＳＥＱ ＩＤ ＮＯ： １５４３， ＳＥ
Ｑ ＩＤ ＮＯ： １５４４， ＳＥＱ ＩＤ ＮＯ：
１５５４， ＳＥＱ ＩＤ ＮＯ： １５７２， Ｓ
ＥＱ ＩＤ ＮＯ： １５７３， ＳＥＱ ＩＤ Ｎ
Ｏ： １５７４， ＳＥＱ ＩＤＮＯ： １５７５，
ＳＥＱ ＩＤ ＮＯ： １５８１， ＳＥＱ ＩＤ Ｎ
Ｏ： １５８２， ＳＥＱ ＩＤ ＮＯ： １５８３，
ＳＥＱ ＩＤ ＮＯ：１５８８， ＳＥＱ ＩＤ Ｎ
Ｏ： １５８９， ＳＥＱ ＩＤ ＮＯ： １５９０，
ＳＥＱ ＩＤ ＮＯ： １５９７， ＳＥＱ ＩＤ
ＮＯ： １５９８， ＳＥＱ ＩＤ ＮＯ： １６２
３， ＳＥＱ ＩＤ ＮＯ： １６４７， ＳＥＱ Ｉ
Ｄ ＮＯ： １６４８， ＳＥＱ ＩＤ ＮＯ： １６
５０， ＳＥＱ ＩＤ ＮＯ： １６５１， ＳＥＱ
ＩＤ ＮＯ： １６５３， １６５４， ＳＥＱ ＩＤ
ＮＯ： １６９２， およびSEQ ID NO:1693 からなる群から選択される。これらのタンパク質または
ポリペプチドは、ファージに由来するＯ１５７：Ｈ７に
特異的なものである。これらタンパク質およびその遺伝
子（または核酸分子）は、Ｏ１５７感染の検出および診
断に有用である。

【００３４】５）調節因子：これらのタンパク質または
ポリペプチドは、配列表： SEQ ID NO: 1147, SEQ ID NO: 1148, SEQ ID NO: 1149,
SEQ ID NO: 1150, SEQID NO: 1151, SEQ ID NO: 1152,
SEQ ID NO: 1153, SEQ ID NO: 1154, SEQ ID NO: 115
5, SEQ ID NO: 1156, SEQ ID NO: 1192., SEQ ID NO: 1
193, SEQ ID NO:1194, SEQ ID NO: 1335, SEQ ID NO: 1
336, SEQ ID NO: 1337, SEQ ID NO: 1402, SEQ ID NO:
1403, SEQ ID NO: 1404, SEQ ID NO: 1405, SEQ ID NO:
1406, SEQ ID NO: 1407, SEQ ID NO: 1468, SEQ ID N
O: 1512, SEQ ID NO: 1513, SEQ IDNO: 1514, SEQ ID N
O: 1515, SEQ ID NO: 1585, SEQ ID NO: 1586, SEQ ID
NO:1656, SEQ ID NO: 1657, SEQ ID NO: 1678, およびS
EQ ID NO: 1695 からなる群から選択される。これらのタンパク質または
ポリペプチドは、Ｏ１５７：Ｈ７に特異的な調節因子で
あり、その遺伝子の発現を阻害する物質の開発に利用可
能である。そのような物質は、Ｏ１５７感染の予防およ
び治療、並びに食品添加物として有用である。さらに、
タンパク質およびその遺伝子（または核酸分子）自体が
Ｏ１５７感染の診断および治療に有用である。

【００３５】６）線毛に関連するタンパク質：これらの
タンパク質またはポリペプチドは、配列表の SEQ ID NO: 274, SEQ ID NO: 275, SEQ ID NO: 276, SE
Q ID NO: 277, SEQ ID NO: 1195, SEQ ID NO: 1196, SE
Q ID NO: 1197, SEQ ID NO: 1241, SEQ ID NO: 1242, S
EQ ID NO: 1243, SEQ ID NO: 1244, SEQ ID NO: 1245,
SEQ ID NO: 1246,SEQ ID NO: 1247, SEQ ID NO: 1248,
SEQ ID NO: 1249, SEQ ID NO: 1250, SEQID NO: 1251,
SEQ ID NO: 1252, SEQ ID NO: 1253, SEQ ID NO: 1254,
SEQ IDNO: 1255, SEQ ID NO: 1256, SEQ ID NO: 1257,
SEQ ID NO: 1427, SEQ ID NO:1428, SEQ ID NO: 1429,
SEQ ID NO: 1430, SEQ ID NO: 1431, SEQ ID NO: 143
2, SEQ ID NO: 1433, SEQ ID NO: 1434, SEQ ID NO: 14
35, SEQ ID NO: 1521, SEQ ID NO: 1522, SEQ ID NO: 1
523, SEQ ID NO: 1524, SEQ ID NO: 1525, SEQ IDNO: 1
548, SEQ ID NO: 1613, SEQ ID NO: 1614, SEQ ID NO:
1659, およびSEQID NO: 1671 からなる群から選択される。これらのタンパク質および
その遺伝子（または核酸分子）は、抗体作製、ワクチン
組成物およびＯ１５７感染の診断等に有用であり得る。
これらのタンパク質またはポリペプチドは、Ｏ１５７：
Ｈ７に特異的な遺伝子の発現を阻害する物質の開発に利
用可能である。そのような物質は、Ｏ１５７感染の予防
および治療、並びに食品添加物として有用である。さら
に、タンパク質およびその遺伝子（または核酸分子）自
体がＯ１５７感染の診断および治療に有用である。

【００３６】７）物質の輸送に関連するタンパク質：こ
れらのタンパク質またはポリペプチドは、配列表： SEQ ID NO: 817, SEQ ID NO: 818, SEQ ID NO: 819, SE
Q ID NO: 820, SEQ ID NO: 821, SEQ ID NO: 822, SEQ
ID NO: 823, SEQ ID NO: 824, SEQ ID NO: 825,SEQ ID
NO: 826, SEQ ID NO: 827, SEQ ID NO: 828, SEQ ID N
O: 829, SEQ ID NO: 830, SEQ ID NO: 831, SEQ ID NO:
832, SEQ ID NO: 833, SEQ ID NO: 834,SEQ ID NO: 83
5, SEQ ID NO: 836, SEQ ID NO: 837, SEQ ID NO: 838,
SEQ ID NO: 839, SEQ ID NO: 840, SEQ ID NO: 841, S
EQ ID NO: 842, SEQ ID NO: 843,SEQ ID NO: 844, SEQ
ID NO: 1198, SEQ ID NO: 1339, SEQ ID NO: 1340, SEQ
ID NO: 1341, SEQ ID NO: 1342, SEQ ID NO: 1343, SE
Q ID NO: 1344, SEQ ID NO: 1345, SEQ ID NO: 1346, S
EQ ID NO: 1347, SEQ ID NO: 1368, SEQ ID NO: 1369,
SEQ ID NO: 1370, SEQ ID NO: 1371, SEQ ID NO: 1458,
SEQ ID NO: 1459,SEQ ID NO: 1461, SEQ ID NO: 14 6
2, SEQ ID NO: 1463, SEQ ID NO: 1464, SEQID NO: 146
5, SEQ ID NO: 1466, SEQ ID NO: 1507, およびSEQ ID
NO: 1679 からなる群から選択される。これらのタンパク質または
ポリペプチドは、Ｏ１５７：Ｈ７に特異的な調節因子で
ある。これらはＯ１５７特異的な選択培地の開発、Ｏ１
５７に選択的な薬剤の開発等に有用であり、その遺伝子
破壊株は弱毒性生ワクチンとして有用であり得る。さら
に、タンパク質およびその遺伝子（または核酸分子）自
体がＯ１５７感染の診断および治療に有用である。

【００３７】８）リポ多糖合成に関連するタンパク質：
これらのタンパク質またはポリペプチドは、配列表： SEQ ID NO: 1533, SEQ ID NO: 1534, SEQ ID NO: 1535,
SEQ ID NO: 1536, SEQID NO: 1395, SEQ ID NO: 1396,
SEQ ID NO: 1397, SEQ ID NO: 1398, SEQ ID NO: 139
9, SEQ ID NO: 1400, SEQ ID NO: 1412, SEQ ID NO: 14
13, SEQ ID NO: 1414, SEQ ID NO: 1415, SEQ ID NO: 1
564, およびSEQ ID NO: 1565 からなる群から選択される。これらのタンパク質および
その遺伝子（または核酸分子）は、抗体作製、ワクチン
組成物およびＯ１５７感染の診断等に特に有用である。
さらに、タンパク質およびその遺伝子（または核酸分
子）自体がＯ１５７感染の診断および治療に有用であ
る。

【００３８】９）代謝に関連するタンパク質：これらの
タンパク質またはポリペプチドは、配列表： SEQ ID NO: 278, SEQ ID NO: 690, SEQ ID NO: 691, SE
Q ID NO: 692, SEQ ID NO: 693, SEQ ID NO: 694, SEQ
ID NO: 695, SEQ ID NO: 696, SEQ ID NO: 697,SEQ ID
NO: 698, SEQ ID NO: 699, SEQ ID NO: 700, SEQ ID N
O: 701, SEQ ID NO: 702, SEQ ID NO: 703, SEQ ID NO:
704, SEQ ID NO: 705, SEQ ID NO: 706,SEQ ID NO: 70
7, SEQ ID NO: 708, SEQ ID NO: 709, SEQ ID NO: 710,
SEQ ID NO: 711, SEQ ID NO: 712, SEQ ID NO: 713, S
EQ ID NO: 714, SEQ ID NO: 715,SEQ ID NO: 716, SEQ
ID NO: 717, SEQ ID NO: 718, SEQ ID NO: 719, SEQ ID
NO: 720, SEQ ID NO: 721, SEQ ID NO: 722, SEQ ID N
O: 723, SEQ ID NO: 724,SEQ ID NO: 725, SEQ ID NO:
726, SEQ ID NO: 727, SEQ ID NO: 728, SEQ ID NO: 72
9, SEQ ID NO: 730, SEQ ID NO: 731, SEQ ID NO: 141
6, SEQ ID NO: 1417, SEQ ID NO: 1472, SEQ ID NO: 15
52, SEQ ID NO: 1556, SEQ ID NO: 1557, SEQ ID NO: 1
616, SEQ ID NO: 1630, SEQ ID NO: 1631, SEQ ID NO:
1660, SEQ IDNO: 1661, およびSEQ ID NO: 1667 からなる群から選択される。これらのタンパク質または
ポリペプチドは、Ｏ１５７：Ｈ７に特異的な代謝に関連
する。故に、これらはＯ１５７特異的な選択培地の開
発、Ｏ１５７に選択的な薬剤の開発等に有用であり、さ
らにその遺伝子破壊株は弱毒性生ワクチンとして有用で
あり得る。また、タンパク質およびその遺伝子（または
核酸分子）自体がＯ１５７感染の診断および治療に有用
である。

【００３９】１０）ＤＮＡ／ＲＮＡのプロセッシングに
関連するタンパク質：これらのタンパク質またはポリペ
プチドは、配列表： SEQ ID NO: 732, SEQ ID NO: 733, SEQ ID NO: 734, SE
Q ID NO: 735, SEQ ID NO: 736, SEQ ID NO: 737, SEQ
ID NO: 738, SEQ ID NO: 739, SEQ ID NO: 740,SEQ ID
NO: 741, SEQ ID NO: 742, SEQ ID NO: 743, SEQ ID N
O: 744, SEQ ID NO: 745, SEQ ID NO: 1199, SEQ ID N
O: 1200, SEQ ID NO: 1201, SEQ ID NO: 1202, SEQ ID
NO: 1203, SEQ ID NO: 1204, SEQ ID NO: 1205, および
SEQ ID NO:1318 からなる群から選択される。これらはＯ１５７に選択的
な薬剤の開発等に有用である。さらに、タンパク質およ
びその遺伝子（または核酸分子）自体がＯ１５７感染の
診断および治療に有用である。

【００４０】１１）病原性に関連するタンパク質：これ
らのタンパク質またはポリペプチドは、配列表： SEQ ID NO: 746, SEQ ID NO: 747, SEQ ID NO: 748, SE
Q ID NO: 749, SEQ ID NO: 750, SEQ ID NO: 751, SEQ
ID NO: 752, SEQ ID NO: 753, SEQ ID NO: 754,SEQ ID
NO: 845, SEQ ID NO: 846, SEQ ID NO: 847, SEQ ID N
O: 848, SEQ ID NO: 849, SEQ ID NO: 850, SEQ ID NO:
851, SEQ ID NO: 852, SEQ ID NO: 853,SEQ ID NO: 85
4, SEQ ID NO: 855, SEQ ID NO: 856, SEQ ID NO: 857,
SEQ ID NO: 858, SEQ ID NO: 859, SEQ ID NO: 860, S
EQ ID NO: 861, SEQ ID NO: 862,SEQ ID NO: 863, SEQ
ID NO: 864, SEQ ID NO: 865, SEQ ID NO: 866, SEQ ID
NO: 867, SEQ ID NO: 868, SEQ ID NO: 869, SEQ ID N
O: 870, SEQ ID NO: 871,SEQ ID NO: 872, SEQ ID NO:
873, SEQ ID NO: 874, SEQ ID NO: 875, SEQ ID NO: 11
29, SEQ ID NO: 1130, SEQ ID NO: 1131, SEQ ID NO: 1
132, SEQ ID NO: 1133, SEQ ID NO: 1134, SEQ ID NO:
1135, SEQ ID NO: 1136, SEQ ID NO: 1137,SEQ ID NO:
1138, SEQ ID NO: 1206, SEQ ID NO: 1207, SEQ ID NO:
1208, SEQID NO: 1209, SEQ ID NO: 1210, SEQ ID NO:
1211, SEQ ID NO: 1310, SEQ IDNO: 1311, SEQ ID NO:
1312, SEQ ID NO: 1313, SEQ ID NO: 1314, SEQ ID N
O:1315, SEQ ID NO: 1316, SEQ ID NO: 1317, SEQ ID N
O: 1321, SEQ ID NO: 1322, SEQ ID NO: 1323, SEQ ID
NO: 1324, SEQ ID NO: 1325, SEQ ID NO: 1326, SEQ ID
NO: 1327, SEQ ID NO: 1328, SEQ ID NO: 1527, SEQ I
D NO: 1528, SEQ IDNO: 1529, SEQ ID NO: 1530, SEQ I
D NO: 1531, SEQ ID NO: 1620, SEQ ID NO:1621, SEQ I
D NO: 1674, およびSEQ ID NO: 1686 からなる群から選択される。これらのタンパク質または
ポリペプチドは、Ｏ１５７の病原性に関連する。故に、
Ｏ１５７に選択的な薬剤の開発等に有用であり、さらに
その遺伝子破壊株は弱毒性生ワクチンとして有用であり
得る。また、タンパク質およびその遺伝子（または核酸
分子）自体がＯ１５７感染の診断および治療に有用であ
る。

【００４１】１２）その他のタンパク質：これらのタン
パク質またはポリペプチドは、配列表： SEQ ID NO: 1014, SEQ ID NO: 1015, SEQ ID NO: 1016,
SEQ ID NO: 1017, SEQID NO: 1018, SEQ ID NO: 1019,
SEQ ID NO: 1020, SEQ ID NO: 1021, SEQ ID NO: 102
2, SEQ ID NO: 1023, SEQ ID NO: 1024, SEQ ID NO: 10
25, SEQ ID NO: 1139, SEQ ID NO: 1140, SEQ ID NO: 1
141, SEQ ID NO: 1142, SEQ ID NO: 1143,SEQ ID NO: 1
144, SEQ ID NO: 1145, SEQ ID NO: 1146, SEQ ID NO:
1319, SEQID NO: 1320, SEQ ID NO: 1381, SEQ ID NO:
1382, SEQ ID NO: 1383, SEQ IDNO: 1384, SEQ ID NO:
1385, SEQ ID NO: 1469, SEQ ID NO: 1470, SEQ ID NO:
1546, SEQ ID NO: 1592, SEQ ID NO: 1593, SEQ ID NO:
1687, およびSEQ ID NO: 1689 からなる群から選択される。これらタンパク質およびそ
の遺伝子（または核酸分子）は、Ｏ１５７感染の検出お
よび診断に有用である。

【００４２】本発明のポリペプチドまたはそのフラグメ
ントは、当該技術分野の標準技術に従って、コードする
本発明の核酸分子を適する発現ベクターに挿入し、得ら
れた組換えベクターを適する宿主細胞に導入し、当該宿
主細胞を培養し、次いで培養した宿主細胞から所望のポ
リペプチドまたはそのフラグメントを抽出することによ
り製造することができる。故に、本発明はまた、本発明
の核酸分子を挿入物として含む組換え発現ベクター、当
該組換えベクターで形質転換した宿主細胞および当該宿
主細胞を培養することからなるＯ１５７：Ｈ７に特異的
なポリペプチドの製造方法に関する。

【００４３】本発明のＯ１５７特異的なポリペプチドま
たはそのフラグメントを組換え技術により製造するため
には、任意の発現系、例えばヒトを含む哺乳類細胞、昆
虫細胞、真糸状菌細胞および酵母細胞等の真核細胞、並
びに例えば大腸菌細胞等の原核細胞を使用することがで
きる。原核細胞は、当該技術分野において公知の任意の
細菌細胞であるが、例えば大腸菌、サルモネラ菌、ノル
カルディア（Norcardia）、コリネバクテリウム（Coryn
ebacterium）、キャンピロバクター（Campylobacter）
およびストレプトミセス（Streptomyces）種が包含され
る（例えばSambrook, Fritsch & Maniatis, Molecular
Cloning; Laboratory Manual 2nd Ed., 1989）。哺乳類
細胞の例には、ＣＯＳ７細胞またはＣＨＯ細胞が含まれ
る。これらの場合、哺乳類細胞での発現のために有用な
常用のプロモーターを用いることができる。例えば、ヒ
ト・サイトメガロウイルス（Human cytomegalo-virus：
ＨＣＭＶ）前期（immediate early）プロモーターを使
用するのが好ましい。また、その他に、本発明のために
用いることのできる哺乳動物細胞における遺伝子発現の
プロモーターとしてはレトロウイルス、ポリオーマウイ
ルス、アデノウイルス、シミアンウイルス４０（ＳＶ４
０）などのウイルスプロモーターやヒト・ポリペプチド
チェーン・エロンゲーション・ファクター１α（ＨＥＦ
−１α）などの哺乳動物細胞由来のプロモーターを用い
ればよい。複製起原（ｏｒｉ）としては、ＳＶ４０、ポ
リオーマウイルス、アデノウイルス、牛パピローマウイ
ルス（ＢＰＶ）の由来のｏｒｉ等を用いることができ、
さらに発現ベクターは選択マーカーとして、ホスホトラ
ンスフェラーゼＡＰＨ（３'）IIあるいはＩ（ｎｅｏ）
遺伝子等を含むことができる。

【００４４】本発明の組換え発現ベクターは、選択マー
カー遺伝子として種々の抗生物質耐性遺伝子や他のマー
カー遺伝子をコードするＤＮＡ配列を包含させるのが好
ましい。マーカー遺伝子の例には、抗スペクチノマイシ
ン遺伝子、アンピシリン耐性遺伝子、ストレプトマイシ
ン耐性遺伝子（ストレプトマイシンホスホトランスフェ
ラーゼ（ＳＰＴ）遺伝子）、カナマイシンまたはジェネ
ティシン耐性のネオマイシンホスホトランスフェラーゼ
（ＮＰＴII）遺伝子、ハイグロマイシン耐性のハイグロ
マイシンホスホトランスフェラーゼ（ＨＰＴ）遺伝子、
チミジンキナーゼ（ＴＫ）遺伝子、大腸菌キサンチン−
グアニンホスホリボシルトランスフエラーゼ（Ｅｃｏｇ
ｐｔ）遺伝子、ジヒドロ葉酸還元酵素（ＤＨＦＲ）遺伝
子、β−グルクロニダーゼ遺伝子、ルシフェラーゼ遺伝
子、β−ガラクトシダーゼ遺伝子、ペルオキシダーゼ遺
伝子等が包含される。

【００４５】本発明の核酸分子または遺伝子中における
Ｏ１５７の特異的な配列を用いて、Ｏ１５７検出のため
のＰＣＲ用オリゴヌクレオチドプライマーを作成し、Ｏ
１５７の迅速診断を行うことができる。基本的に、すべ
てのＯ１５７の特異的な配列は、ＰＣＲ法による迅速診
断法に有用となりうる。故に、本発明は、前記オリゴヌ
クレオチドプライマーを用いるＯ１５７感染の検出また
は診断方法に関する。さらに、前記オリゴヌクレオチド
をハイブリダイゼーション用のプローブとして用いるこ
とができる。本発明のオリゴヌクレオチドの長さは、少
なくとも８ヌクレオチド、好ましくは１５ヌクレオチド
またはそれ以上であるが、遺伝子工学における標準的技
術を参照して適宜決定することができる。

【００４６】本発明はまた、Ｏ１５７特異的な核酸配列
を有する核酸分子に加えて、他の大腸菌（例えばＫ−１
２株）にも存在するが、Ｏ１５７特異的な突然変異した
核酸配列を有する核酸分子およびその使用方法に関す
る。そのような核酸配列としては、例えばソルビトール
利用能の低下、β？グルクロニダーゼ活性の欠如に関連
する遺伝子における突然変異した核酸配列を挙げること
ができる。

【００４７】本発明のＯ１５７特異的核酸分子、これに
包含される遺伝子、前記遺伝子にコードされるペプチド
および核酸配列は、Ｏ１５７感染の診断、並びにＯ１５
７感染およびこれにより引き起こされる病態の予防およ
び／または治療に有用である。それらはまた、試料中の
Ｏ１５７の存在の検出およびその菌株の型別に使用する
ことができる。さらに、Ｏ１５７感染およびこれにより
引き起こされる病態の予防および／または治療に有用な
化合物のスクリーニングに使用することもできる。

【００４８】本発明はまた、Ｏ１５７感染を検出するた
めのプライマーまたはプローブとして有用なオリゴヌク
レオチドに関する。さらに、本発明の遺伝子および／ま
たはポリヌクレオチドを含むワクチン組成物、並びにＯ
１５７感染およびこれにより引き起こされる病態の予防
および／または治療方法も本発明の範囲に包含される。

【００４９】従って、本発明は、配列表に示される、Ｏ
１５７特異的なまたはＯ１５７特異的な突然変異したヌ
クレオチド配列または前記ヌクレオチド配列と相補的な
ヌクレオチド配列の少なくとも８ヌクレオチドから構成
されるヌクレオチド配列からなるオリゴまたはポリヌク
レオチドに関する。また、本発明は、ハイブリダイゼー
ション用プローブまたはＰＣＲ用プライマーとして用い
る、本発明のオリゴまたはポリヌクレオチドの使用に関
する。プライマーとして用いるオリゴヌクレオチドは、
少なくとも８ヌクレオチド、好ましくは1５ヌクレオチ
ド、さらに好ましくは少なくとも２０またはそれ以上の
ヌクレオチドから構成される。プローブは少なくとも２
０〜３０ヌクレオチドから構成される。プローブとして
使用する核酸は当該技術分野における標準技術により標
識することができる。

【００５０】本発明のオリゴまたはポリヌクレオチドを
ＰＣＲ用プライマーとして用いて、Ｏ１５７の迅速診断
を行うことができる。基本的に、すべてのＯ１５７の特
異的な配列は、ＰＣＲ法による迅速診断法に有用となり
うる。故に、本発明は、前記オリゴヌクレオチドプライ
マーを用いるＯ１５７感染の検出または診断方法に関す
る。

【００５１】本発明は、配列表に示されるアミノ酸配列
を有するＯ１５７特異的なポリペプチドまたはそのフラ
グメントの少なくとも１種の有効量からなるＯ１５７感
染の予防または治療のためのペプチドワクチン製剤に関
する。当該ワクチン製剤は、好ましくは医薬的に許容さ
れる担体、例えば当該技術分野において公知のアジュバ
ントを含有する。

【００５２】本発明はまた、前述のＯ１５７特異的なポ
リペプチドまたはそのフラグメントをコードするポリヌ
クレオチドの少なくとも１からなるＯ１５７感染の予防
または治療のためのＤＮＡワクチン製剤に関する。当該
ワクチン製剤は、好ましくは医薬的に許容される担体、
例えば当該技術分野において公知のアジュバントおよび
／またはトランスフェクション試薬等を含有する。トラ
ンスフェクション試薬には、生体の細胞中にＤＮＡワク
チンをトランスフェクションするのに適するリポソー
ム、金粒子およびカチオン性ポリマーが包含される。病
原性細菌に対するＤＮＡワクチンの使用は、例えばDNA
ワクチン研究の例Han T. K. et al., DNACell Biol. 20
(9), pp. 595-601, 2001; Miyaji E. N. et al., Vacci
ne 20(5-6), pp. 805-12, 2001に記載されており、本明
細書にて引用することによりその内容を組み入れる。

【００５３】本発明は、患者におけるＯ１５７感染の危
険の低減方法または治療方法に関する。この方法は、Ｏ
１５７感染の危険性の低減または感染の治療を提供する
ように本発明のワクチン製剤を患者に投与することをか
らなる。

【００５４】他の態様においては、本発明は、本発明の
ワクチン製剤を製造する方法に関する。ペプチドワクチ
ン製剤を製造する方法は、配列表に示されるアミノ酸配
列を有するＯ１５７特異的なポリペプチドまたはそのフ
ラグメントの少なくとも１種を医薬的に許容される担体
と配合することを包含する。

【００５５】ＤＮＡワクチン製剤を製造する方法は、前
記ポリペプチドまたはそのフラグメントの少なくとも１
種をコードするポリヌクレオチドを患者において発現さ
せうる発現ベクターに挿入し、前記発現ベクターの有効
量を医薬的に許容される担体と配合することを包含す
る。ヒトを含むほ乳類と大腸菌では、コドンの使用頻度
が相違する可能性がある。この場合、標準的遺伝子工学
技術を用いてＯ１５７にいて頻度の高いコドンをほ乳類
において頻度の高いものに改変することにより、Ｏ１５
７感染を治療または予防すべき患者において所望のポリ
ペプチドのｍＲＮＡの翻訳効率を向上させることができ
る。また、発現ベクターにおいてサイトメガロウイルス
由来のイントロンＡ等の配列を包含させて、所望のポリ
ペプチドの発現を高めることができる。また、本発明の
ＤＮＡワクチン組成物をヒトに投与する場合、組換え発
現ベクターは、ＳＶ４０由来でない複製起点を含むもの
が好ましい。ＳＶ４０由来の配列は癌原性を有する可能
性があり好ましくない。この目的において使用し得る複
製起点は、例えば他のウイルス、原核細胞、酵母または
動物細胞などの真核細胞由来の複製起点が挙げられる
が、これらに限定されない。

【００５６】本発明はまた、Ｏ１５７特異的なポリペプ
チドまたはそのフラグメントと選択的に反応する抗体に
関する。抗タンパク質／抗ペプチド抗血清またはモノク
ローナル抗体は、標準プロトコールに従って作成するこ
とができる（例えばAntibodies: A Laboratory Manual,
Harlow & Lane編, Cold Spring Harbor Press, 1988を
参照）。本発明において、用語「抗体分子」の意味に
は、全抗体、慣用の技術を用いてフラグメント化して得
られる抗体フラグメント、例えばFab'およびF(ab')₂フ
ラグメント、さらに遺伝子工学的な手法により得られる
一本鎖Ｆｖ（scFv）が包含される。本発明の抗体分子は
また、抗体フラグメントまたは一本鎖Ｆｖからなる二重
特異性抗体またはキメラ抗体を包含する。この場合、同
一のＯ１５７特異的なポリペプチドに対する異なる２つ
の抗体、異なるＯ１５７ポリペプチドを認識する２つの
抗体、またはポリペプチドに対する１つの抗体とＯ１５
７には関連しないエピトープを認識する１つの抗体から
なる。

【００５７】Ｏ１５７特異的な遺伝子の中で、Ｏ１５７
に特異的な代謝機能に関わるものはＯ１５７選択用の新
規培地の開発に使用可能である。現在使用されている選
択培地はソルビトールの利用能の低下、β−グルクロニ
ダーゼ活性の欠如、亜テルル酸耐性能などの比較的Ｏ１
５７に特異的な特性を利用したものであが、本発明にお
いて見出された代謝系遺伝子の中には、これらよりさら
にＯ１５７に対する特異性が高いものが存在する可能性
があり、そのような特性はＯ１５７の選択に好ましく、
ソルビトールの利用能の低下、β−グルクロニダーゼ活
性の欠如および／または亜テルル酸耐性能と組み合わせ
るのがさらに好ましい。

【００５８】Ｏ１５７の病原性に関連するポリペプチ
ド、細菌細胞表層タンパク質、調節タンパク質、代謝系
に関連するタンパク質およびこれをコードする核酸分子
は、Ｏ１５７の病原性発現を選択的に阻害する薬剤の開
発に有用である。故に、本発明は、その発現および／ま
たは機能を阻害するような化合物の検索あるいは合成を
行うことからなる、Ｏ１５７に関連する病態の予防およ
び／または治療に有用な薬剤の検索またはスクリーニン
グ方法もまた包含する。本発明の方法によれば、Ｏ１５
７に関連する病態の新規予防薬および／または治療薬が
提供されうる。

【００５９】また、本発明により示された病原性に関連
する遺伝子、特に新規毒素から組換えタンパク質を製造
し、毒素の機能を解析し、その阻害剤を検索することが
できる。故に、本発明は新規毒素に対する阻害剤の検索
またはスクリーニング方法に関する。さらに、精製タン
パク質とそのアミノ酸配列情報を基に、立体構造を決定
し、コンピュータを用いた阻害物質のデザインおよびそ
の合成が可能である。これらの阻害物質は、従来の抗生
剤とは全く異なったタイプの治療薬となるばかりか、Ｏ
１５７の発育を選択的に阻害しうる食品添加物となる。

【００６０】また、本発明のＯ１５７特異的な病原性遺
伝子、細菌細胞表面タンパク質の遺伝子および調節遺伝
子は、その破壊株の作成することによって弱毒生ワクチ
ンを開発することができる。また、これらに対応する機
能不全の遺伝子を他のワクチン株にクローン化すること
によっても弱毒生ワクチンを作製することができる。

【００６１】一方、生体内外でのＯ１５７の増殖に必須
の代謝機能コードする遺伝子または調節遺伝子は、それ
らの遺伝子破壊株の作成することによって、実験室内の
特定な条件では増殖可能でも、ヒトを含む哺乳動物の生
体内では増殖できない変異株を作成することができる。
このような株は、弱毒生ワクチンとして有用である。

【００６２】本発明の態様には、本発明の核酸配列また
は遺伝子の一部またはすべてを包含するＤＮＡマイクロ
アレイまたはチップが含まれる。好ましくは、（ａ）SE
Q IDNO：1, SEQ ID NO：132, SEQ ID NO：244, SEQ ID
NO：337, SEQ ID NO：410,SEQ ID NO：484, SEQ ID N
O：554, SEQ ID NO：630, SEQ ID NO：689, SEQ ID N
O：755, SEQ ID NO：816, SEQ ID NO：876, SEQ ID N
O：927, SEQ ID NO：978,SEQ ID NO：1013, SEQ ID N
O：1029, SEQ ID NO：1055, SEQ ID NO：1060, SEQID N
O：1093, SEQ ID NO：1128, SEQ ID NO：1157, SEQ ID
NO：1191, SEQ ID NO：1212, SEQ ID NO：1240, SEQ ID
NO：1258, SEQ ID NO：1274, SEQ ID NO：1288, SEQ I
D NO：1302, SEQ ID NO：1309, SEQ ID NO：1321, SEQ
ID NO：1329,SEQ ID NO：1338, SEQ ID NO：1348, SEQ
ID NO：1359, SEQ ID NO：1366, SEQID NO：1374, SEQ
ID NO：1380, SEQ ID NO：1386, SEQ ID NO：1394, SEQ
IDNO：1401, SEQ ID NO：1408, SEQ ID NO：1411, SEQ
ID NO：1418, SEQ ID NO：1426, SEQ ID NO：1436, SE
Q ID NO：1443, SEQ ID NO：1450, SEQ ID NO：1457, S
EQ ID NO：1460, SEQ ID NO：1467, SEQ ID NO：1471,
SEQ ID NO：1473, SEQ ID NO：1478, SEQ ID NO：1487,
SEQ ID NO：1489, SEQ ID NO：1494, SEQ IDNO：1499,
SEQ, ID NO：1501, SEQ ID NO：1506, SEQ ID NO：150
8, SEQ ID NO：1510, SEQ ID NO：1511, SEQ ID NO：15
16, SEQ ID NO：1520, SEQ ID NO：1526, SEQ ID NO：1
532, SEQ ID NO：1537, SEQ ID NO：1540, SEQ ID NO：
1545,SEQ ID NO：1547, SEQ ID NO：1549, SEQ ID NO：
1551, SEQ ID NO：1553, SEQID NO：1555, SEQ ID NO：
1558, SEQ ID NO：1563, SEQ ID NO：1566, SEQ ID N
O：1569, SEQ ID NO：1571, SEQ ID NO：1576, SEQ ID
NO：1580, SEQ ID NO：1584, SEQ ID NO：1587, SEQ ID
NO：1591, SEQ ID NO：1594, SEQ ID NO：1596,SEQ ID
NO：1599, SEQ ID NO：1601, SEQ ID NO：1603, SEQ I
D NO：1604, SEQID NO：1605, SEQ ID NO：1607, SEQ I
D NO：1612, SEQ ID NO：1615, SEQ IDNO：1617, SEQ I
D NO：1619, SEQ ID NO：1622, SEQ ID NO：1624, SEQ
ID NO：1626, SEQ ID NO：1627, SEQ ID NO：1629, SEQ
ID NO：1632, SEQ ID NO：1635, SEQ ID NO：1636, SE
Q ID NO：1637, SEQ ID NO：1639, SEQ ID NO：1640, S
EQ ID NO：1643, SEQ ID NO：1646, SEQ ID NO：1649,
SEQ ID NO：1652, SEQ IDNO：1655, SEQ ID NO：1658,
SEQ ID NO：1660, SEQ ID NO：1662, SEQ ID NO：1664,
SEQ ID NO：1666, SEQ ID NO：1668, SEQ ID NO：166
9, SEQ ID NO：1670, SEQ ID NO：1672, SEQ ID NO：16
73, SEQ ID NO：1675, SEQ ID NO：1677,SEQ ID NO：16
80, SEQ ID NO：1682, SEQ ID NO：1683, SEQ ID NO：1
685, SEQID NO：1688, SEQ ID NO：1690, SEQ ID NO：1
691, SEQ ID NO：1694, SEQ ID NO：1696, SEQ ID NO：
1699, SEQ ID NO：1700, SEQ ID NO：1701, SEQ ID N
O：1704, SEQ ID NO：1705, SEQ ID NO：1706, SEQ ID
NO：1707, SEQ ID NO：1708,SEQ ID NO：1709, SEQ ID
NO：1710, SEQ ID NO：1711, SEQ ID NO：1712, SEQID
NO：1713, SEQ ID NO：1715, SEQ ID NO：1716, SEQ ID
NO：1717, SEQ IDNO：1718,, SEQ ID NO：1719, SEQ I
D NO：1720, SEQ ID NO：1721, SEQ ID NO：1722, SEQ
ID NO：1723, SEQ ID NO：1724, SEQ ID NO：1725, SEQ
ID NO：1726, SEQ ID NO：1727, SEQ ID NO：1728, SE
Q ID NO：1729, SEQ ID NO：1730,SEQ ID NO：1731, SE
Q ID NO：1732, SEQ ID NO：1733, SEQ ID NO：1734, S
EQID NO：1735, SEQ ID NO：1736, SEQ ID NO：1737, S
EQ ID NO：1738, SEQ ID NO：1739, SEQ ID NO：1740,
SEQ ID NO：1741, SEQ ID NO：1742, SEQ ID NO：1743,
SEQ ID NO：1744, SEQ ID NO：1745, SEQ ID NO：174
6, SEQ ID NO：1747,SEQ ID NO：1748, SEQ ID NO：174
9, SEQ ID NO：1750, SEQ ID NO：1751, SEQID NO：175
2, SEQ ID NO：1753, SEQ ID NO：1754, SEQ ID NO：17
55, SEQ IDNO：1756, SEQ ID NO：1757, SEQ ID NO：17
58, SEQ ID NO：1759, SEQ ID NO：1760, SEQ ID NO：1
761, SEQ ID NO：1762, SEQ ID NO：1763, SEQ ID NO：
1764, SEQ ID NO：1765, SEQ ID NO：1766, SEQ ID N
O：1767, SEQ ID NO：1768, SEQ ID NO：1769, SEQ ID
NO：1770, SEQ ID NO：1771, SEQ ID NO：1772, SEQ ID
NO：1773, SEQ ID NO：1774, SEQ ID NO：1775, SEQ ID
NO：1776, SEQ ID NO：1777, SEQ ID NO：1778, SEQ I
D NO：1779, SEQ ID NO：1780, SEQ ID NO：1781, SEQ
ID NO：1782, SEQ ID NO：1783, SEQ ID NO：1784, SEQ
ID NO：1785,SEQ ID NO：1786, SEQ ID NO：1787, SEQ
ID NO：1788, SEQ ID NO：1789, SEQID NO：1790, SEQ
ID NO：1791, SEQ ID NO：1792, SEQ ID NO：1793, SE
Q ID NO：1794, SEQ ID NO：1795, SEQ ID NO：1796, S
EQ ID NO：1797, SEQ ID NO：1798, SEQ ID NO：1799,
SEQ ID NO：1800, SEQ ID NO：1801, SEQ ID NO：1802,
SEQ ID NO：1803, SEQ ID NO：1804, SEQ ID NO：1805,
SEQ ID NO：1806, SEQID NO：1807, SEQ ID NO：1808,
SEQ ID NO：1809, SEQ ID NO：1810, SEQ IDNO：1811,
SEQ ID NO：1812, SEQ ID NO：1813, SEQ ID NO：181
4, SEQ ID NO：1815, SEQ ID NO：1816, SEQ ID NO：18
17, SEQ ID NO：1818, SEQ ID NO：1819, SEQ ID NO：1
820, SEQ ID NO：1821, SEQ ID NO：1822, SEQ ID NO：
1823, SEQ ID NO：1824, SEQ ID NO：1825, SEQ ID N
O：1826, SEQ ID NO：1827, SEQ IDNO：1828, SEQ ID N
O：1829, SEQ ID NO：1830, SEQ ID NO：1831, SEQ ID
NO：1832, SEQ ID NO：1833, SEQ ID NO：1834, SEQ ID
NO：1835, SEQ ID NO：1836, SEQ ID NO：1837, SEQ I
D NO：1838, SEQ ID NO：1839, SEQ ID NO：1840,SEQ I
D NO：1841, SEQ ID NO：1842, SEQ ID NO：1843, SEQ
ID NO：1844, SEQID NO：1845, SEQ ID NO：1846, SEQ
ID NO：1847, SEQ ID NO：1848, SEQ ID NO：1849, SEQ
ID NO：1850, SEQ ID NO：1851, SEQ ID NO：1852, SE
Q ID NO：1853, SEQ ID NO：1854, SEQ ID NO：1855, S
EQ ID NO：1856, SEQ ID NO：1857,SEQ ID NO：1858, S
EQ ID NO：1859, SEQ ID NO：1860, SEQ ID NO：1861,
SEQID NO：1862, SEQ ID NO：1863, SEQ ID NO：1864,
SEQ ID NO：1865, およびSEQ ID NO：1866からなる群か
ら選択されるヌクレオチド配列またはその部分配列およ
び／または（ｂ）（ａ）に示される配列に相補的な配列
からなるオリゴまたはポリヌクレオチドを含むＤＮＡチ
ップまたはその製造方法である。そのようなＤＮＡマイ
クロアレイまたはチップは、当該分野における標準的技
術により本発明の核酸配列または遺伝子を用いて製造す
ることができる（例えば、"DNA Microarrays: A Practi
cal Approach", Mark Schena, ed. Oxford: Oxford Uni
versity Press, 1999, ISBN 0-19-963777-8; "Microarr
ay Biochip Technology", MarkSchena, ed. Natick, M
A: Eaton Publishing, 2000, ISBN 1-881299-37-6; "DN
A Arrays: Methods and Protocols", Jang B. Rampal,
ed. Totowa, NJ: HumanaPress, 2001, ISBN 0-89603-82
2-Xを参照）。このＤＮＡマイクロアレイまたはチップ
は、Ｏ１５７特異的遺伝子の機能解析、Ｏ１５７の菌株
の型別、他のＯ１５７菌株や他のタイプの大腸株に類似
の遺伝子があるか否かの検索などに利用可能である。Ｄ
ＮＡアレイを使用して菌株の型別は、例えばSalama N.
et al., Proc. Natl. Acad. Sci. U A. 97(26),pp. 146
68-73, 2000に記載されている。ＤＮＡアレイを使用し
て病原菌を検出する技術は、例えばCall D. R. et al.,
IntJ Food Microbiol, 67(1-2), pp.71-80, 2001に記
載されている。また、ＤＮＡアレイを使用して遺伝子の
発現を解析する技術は、例えばHarrington C. A. eta
l., Curr. Opin. Microbiol. 3(3), pp.285-91, 2000に
記載されている。これらの文献は、本明細書において引
用することによりその内容を組み入れる。

【００６３】定義 本発明において、用語「Ｏ１５７に特異的」および「Ｏ
１５７：Ｈ７に特異的」は、非病原性大腸菌Ｋ？１２株
には存在ぜず、Ｏ１５７（またはＯ１５７：Ｈ７）に存
在することを意味する。故に、場合により同一のものま
たはこれに類似のものが他のタイプの大腸菌株や他の細
菌種に存在する可能性がある。

【００６４】本発明において、用語「ハイブリダイズす
る」とは、ストリンジェントな条件下、例えば０.５×
ＳＳＣ溶液中、６５℃またはこれに相当する条件下にて
ハイブリダイズすることを意味する。

【００６５】本明細書において用いられる「細胞表面タ
ンパク質」の語は、すべての表面に接近可能なタンパク
質、たとえば内膜および外膜タンパク質、細胞壁に接着
するタンパク質ならびに分泌タンパク質を意味する。

【００６６】用語「オープンリーディングフレーム（Ｏ
ＲＦ）」はポリペプチドまたはその部分をコードする核
酸の領域であり、開始コドンから停止コドンまたは停止
コドンから停止コドンより決定することができる。

【００６７】本明細書において用いる用語「コーディン
グ配列」は、適当な調節配列の制御下に置いた場合、ｍ
ＲＮＡへの転写および／またはポリペプチドへの翻訳が
行われる核酸である。コーディング配列にはそれらに限
定されるものではないがｍＲＮＡ、合成ＤＮＡ、および
組換え核酸配列が包含される。

【００６８】本明細書において、ポリペプチドの「部
分」または「フラグメント」は、少なくとも１０アミノ
酸残基、好ましくは少なくとも２０アミノ酸残基、より
好ましくは少なくとも４０アミノ酸残基からなるオリゴ
またはポリペプチドを意味する。また、ヌクレオチド配
列の「部分」または「フラグメント」は、少なくとも２
０ヌクレオチドまたはそれ以上、好ましくは５０ヌクレ
オチドまたはそれ以上から構成されるものを意味する。

【００６９】本明細書において、用語「発現制御エレメ
ント」または「発現制御配列」は、連結されたコード配
列またはＯＲＦの発現を誘導および／または調節しうる
塩基配列を意味する。また、用語「作動的に連結する」
語は、前記発現制御エレメントまたは配列が、コード配
列またはＯＲＦの転写を可能にし得るような様式でコー
ド配列またはＯＲＦに連結されることを意味する。

【００７０】本発明において、物質の代謝とは、物質の
発現、機能、作用または調節の任意の局面を意味する。
物質の代謝には、物質の修飾たとえば物質の共有結合ま
たは非共有結合修飾を包含する。物質の代謝にはその物
質が誘導する、他の物質中の修飾たとえば物質の共有結
合または非共有結合修飾を包含する。物質の代謝はま
た、物質の分布の変化を包含する。物質の代謝にはその
物質が誘導する他の物質の分布の変化が包含される。

【００７１】本発明において、物質の輸送とは、物質の
細胞外から細胞内への運搬、細胞内での物質の運搬、細
胞外への物質の分泌および放出を意味する。

【００７２】本発明の実施に際しては、特に他の指示が
ない限り、当該技術分野における慣用技術を用いること
ができる。このような技術は、例えばSambrook, Fritsc
h &Maniatis, Molecular Cloning; Laboratory Manual
2nd Ed. (1989); DNA Cloning, Volume (D.N. Glover E
d. 1985); Oligonucleotide Synthesis (M.J. GaitEd．
1984); Nucleic Acid Hybridization (B.D. Hames & S.
J. Higgins Ed. 1984); Methods in Enzymology (Acade
mic Press,Inc.), Vol. 154 & Vol．155 (Wu& Grossman
ed.) およびPCR-A Practical Approach (McPherson, Q
uirke & Taylor, ed. 1991)に開示されている。

【００７３】本発明の核酸分子はポリメラーゼ連鎖反応
(ＰＣＲ)を用い上述のＯ１５７：Ｈ７堺株のＤＮＡから
直接得ることができ、増幅された産物の信頼性は慣用の
配列決定法でチェックすることができる。本発明に記載
された所望の配列を有するクローンはＰＣＲによるライ
ブラリーのスクリーニング、または本技術分野において
周知のようにライブラリーコロニーもしくはプラークの
フィルターリフトへの合成オリゴヌクレオチドプローブ
を用いるライブラリーのスクリーニングによっても得る
ことができる（例えばSambrookら、Molecular Clonin
g，A LaboratoryManual 2nd edition, 1989，Cold Spri
ng Harbor Press，NY）。Ｏ１５７:Ｈ７特異的なポリペ
プチドをコードする核酸もまた同様に取得することがで
きる。

【００７４】本発明の核酸はまた、標準技術を用いて化
学的に合成することもできる。ポリデオキシヌクレオチ
ドを化学的に合成する様々な方法が知られている（たと
えば、Itakuraら、米国特許4,598,049; Caruthersら、
米国特許4,458,066；ならびにItakuraら、米国特許4,40
1,796 および4,373,071参照、引用により本明細書に導
入される）。

【００７５】本発明を下記の実施例により説明するが、
本発明はこれらに限定されるものではない。

【００７６】

【実施例】実施例１：腸管出血性病原性大腸菌Ｏ１５
７：Ｈ７のゲノムのヌクレオチド配列の決定 腸管出血性病原性大腸菌Ｏ１５７：Ｈ７の染色体の全ヌ
クレオチド配列を決定し、非病原性大腸菌Ｋ−１２には
存在しないＯ１５７：Ｈ７特異的領域およびヌクレオチ
ド配列を同定した。本実施例において、1996 年に大阪
府堺市を中心に発生したＯ１５７：Ｈ７集団感染の際
に、典型的な出血性腸炎を呈した患者より分離されたＯ
１５７：Ｈ７菌株（RIMD 0509952）を用いた。この菌株
は大阪大学微生物学病研究所附属エマージング感染症研
究センター内、微生物株保存施設において保管され、Ａ
ＴＣＣ（American Type Culture Collection）には、現
在登録手続き中である。この菌株を培養し、常法に従っ
てゲノムＤＮＡを調製した。１〜２ＫｂｐのサイズのＤ
ＮＡ断片を挿入したランダムショットガンライブラリー
を作成し、５０１０５個のクローンの塩基配列を決定し
た。このうち、１９９６９個のクローンに関しては挿入
断片の両端の塩基配列を決定した（whole genome rando
m shotgun sequencing）。また、２０Ｋｂｐ前後の挿入
DNA断片をもつラムダファージライブラリーを作成し、8
6個のクローンの全配列をそれぞれ個別に決定した。Phr
ed/Phrap/consedを用いて得られた全配列データのアッ
センブリーを行い、１Ｋｂｐ以上のコンティグは１１１
個を得た。最終的に、各コンティグ間のギャップ領域を
ＰＣＲにより増幅し、各々のPCR産物の塩基配列を決定
することにより、Ｏ１５７：Ｈ７の染色体の全ヌクレオ
チド配列を決定した。次いで、Genome Gambler version
1.41、GLIMMER 2.01、 BLASTなどのプログラムを使用
してヌクレオチド配列を解析し、タンパク質コーディン
グ領域を決定した。さらに、Ｏ１５７：Ｈ７の染色体配
列を非病原性大腸菌Ｋ−１２（MG1655株）の染色体配列
とMUMmerプログラムを用いて比較し、Ｋ−１２には存在
せずＯ１５７：Ｈ７にのみ特異的に存在する２０ｂｐ以
上の領域を全て同定した。決定したＯ１５７：Ｈ７の染
色体のヌクレオチド配列は、遺伝子データバンクＤＤＢ
Ｊにおいて２０００年６月２６日にアクセッション番
号：ＢＡ０００００７として登録されている。

【００７７】実施例２ ＰＣＲ法によるＯ１５７の検出 Ｏ１５７堺株に特異的に存在するウレアーゼ遺伝子のヌ
クレオチド配列を基にウレアーゼ遺伝子を増幅できるオ
リゴヌクレオチドプライマーを合成した。Ｏ１５７堺株
または種々の大腸菌菌株を試料として、合成したプライ
マーを用いて常法に従ってＰＣＲ法によるＯ１５７特異
的ウレアーゼ遺伝子の検出を行った。その結果、ウレア
ーゼ遺伝子はＯ１５７を含む腸管出血性病原性大腸菌の
みに検出され、が他のタイプの大腸菌では検出されなか
った。また、Ｏ１５７とその近縁株の腸管出血性病原性
大腸菌には存在することがわかり、これらのプライマー
がＯ１５７の迅速な同定・診断に利用できることが示さ
れた。

【００７８】実施例３ ＰＣＲ法によるＯ１５７の分子
疫学 Ｏ１５７ 堺株のヌクレオチド配列の情報を基に、Ｏ１
５７に特異的な配列を増幅するオリゴヌクレオチドプラ
イマーを合成した。このプライマーを用いて多数の他の
Ｏ１５７株をＰＣＲ法で調べると、菌株によって特異的
なバンドが検出されたり、されなかったりした。これは
菌株により特異的な配列の有無を示しており、菌株間で
違いの多い領域が同定できた。これらの領域を増幅する
プライマーを用いて、Ｏ１５７の菌株型別が可能でとな
った。

【００７９】実施例４ ヌクレオチド配列の診断への応
用 実施例１にて得られた遺伝情報を解析した結果、Ｏ１５
７に特異的に存在するサリチル酸分解遺伝子の存在が示
唆された。このため前記サリチル酸分解遺伝子の機能を
利用して、サリチル酸を炭素源とする培地を作成し、そ
して培養実験を行った。その結果、Ｏ１５７はこの培地
で増殖可能であり、この培地を用いてＯ１５７を選択的
に分離できる可能性が示された。

【００８０】実施例５ ヌクレオチド配列の診断への応
用 実施例１にて得られた遺伝情報を解析した結果、β−グ
ルクロニダーゼ遺伝子コーディング配列（SEQ ID NO:18
65）、特異的PTSエンザイムIIBとIIC遺伝子のコーディ
ング配列（SEQ ID NO:1866）に変異があることが明らか
になった。これらの変異はフレームシフト突然変異（fr
aｍeshift mutation）を包含していた。このため、この
変異に対応するオリゴヌクレオチドプライマーを合成
し、このプライマーを用いたＰＣＲ法により、Ｏ１５７
および他の菌株の検出を行った。その結果、β−グルク
ロニダーゼの欠失およびソルビトール利用能の低下を、
菌の培養を行わずに確認することができた。同様に、亜
テルル酸耐性遺伝子を検出するプライマーそ合成して同
様にＰＣＲ法を実施した。この結果、亜テルル酸耐性遺
伝子における変異を検出することができた。さらに、こ
れらの３種類のプライマーを用いたＰＣＲ法を組み合わ
せて使うことにより、より精度の高い診断結果が得られ
た。本実施例により、これらのプライマーがＯ１５７の
迅速診断に応用でき得ることが示された。

【００８１】実施例６ ポリペプチドの発現 Ｏ１５７に特異的に存在する菌体表層タンパク質遺伝子
をクローン化し、組み換えタンパク質の大量産生系を作
成した。この系を用いて組み換えタンパク質を精製し、
患者血清中の抗体測定システムを作成した。このシステ
ムはＯ１５７の血清診断に利用できることを示した。

【００８２】実施例７ ヌクレオチド配列の診断への応
用 実施例１において決定したヌクレオチド配列情報を基
に、新しく見つかった毒素遺伝子をクローン化し、組み
換えタンパク質の大量産生系を作成した。この系を用い
て組み換えタンパク質を精製し、毒素の機能を解析する
とともに、阻害剤を検索することができる。また、精製
タンパク質とそのアミノ酸配列情報を基に、立体構造を
決定し、コンピュータを用いた阻害物質のデザインと合
成が可能である。これらの阻害物質は、従来の抗生剤と
は全く異なったタイプの治療薬となる。

【００８３】実施例８ ＤＮＡワクチン Ｏ１５７に特異的に存在する菌体表層タンパク質遺伝子
をサルモネラ菌のワクチン株にクローン化し、Ｏ１５７
特異的な菌体表層タンパク質がサルモネラワクチン株の
菌体表層に発現されることを確認した。このワクチン株
はＯ１５７に対するワクチンとして使用することが可能
である。

【００８４】実施例９ 弱毒生ワクチン Ｏ１５７に特異的に存在する菌体表層タンパク質をコー
ドする核酸分子をサルモネラ菌に適する発現ベクターに
組み込み、これを弱毒サルモネラ菌のワクチン株にクロ
ーン化した。次いで、Ｏ１５７特異的な表層タンパク質
がサルモネラワクチン株の菌体表層に発現されることを
確認した。このワクチン株はＯ１５７に対する生ワクチ
ンとして使用することができる。

【００８５】実施例１０ ＤＮＡマイクロアレイ Ｏ１５７特異的遺伝子をＰＣＲ法で増幅し、常法に従っ
てＤＮＡチップを作成した。種々の培養条件で培養した
Ｏ１５７菌体からｍＲＮＡを調製して、このＤＮＡチッ
プを用いて解析した。この結果、Ｏ１５７遺伝子の発現
調節機構、どの遺伝子がどのような条件で発現されるか
など、様々な研究が可能となる。

【００８６】

【産業上の利用可能性】本発明によれば、腸管出血性病
原性大腸菌Ｏ１５７：Ｈ７に特異的なヌクレオチド配列
およびこれにコードされるポリペプチドが提供される。
これらは、感染の検出および／または治療に有用となり
うる。また、本発明によれば、Ｏ１５７感染を予防また
は治療するためのワクチン組成物が提供される。さら
に、新規医薬および食品添加物のスクリーニング方法、
Ｏ１５７に関連する病態の新規予防および／または治療
方法の可能性が提供される。

【００８７】

【配列表】 <110> Tsukuba Univ. <120> Enterohemorragic Escherichia coli O157：H7 specific polynucleotide molecule s and polypeptides and use thereof <130> NP-1256 <140> <141> 2002-01-24 <150> JP2001-112010 <151> 2001-01-24 <160> 1866 <210> 1 <211> 91772 <212> DNA <213> Escherichia coli O157:H7 <400> 1 cagatacccc gcagccaaaa tcaacaaaat gccaaaaggt tctgttcctg ccctgcaaca 60 agaaatgctg cgacgtgtca gtaaacgtta tgacgatgta gaagtgatca tcaaatccac 120 cagcaacgat ggcctttcag ttactcgcac cgccgataaa gattctgcaa aaacttttgt 180 tcaggagacg ctgaaagata cctgggagtc tgctgacgag tggtttgttc gctaattaac 240 gagtaaaatc agtaacggct ggaaatcatt caatactcgc actatcgaaa gttcaccagc 300 caaccgcagc acgttcttgc atacgaggtg ccgcgtttta catgctgtac cgagaattaa 360 tttcatttta cgaaaagtta acccgccatt gctatcttaa ttttttaaaa cgaagttacc 420 tctgtcagag tcaaaagcac aattatctct tcctacaatc attgaaactg cgattgattc 480 cctgctcaaa ggatgagccg cccttgtttt aacaagatat attaatgaca ttttatcata 540 caacatacaa acatttgaat tcattgaatt cctcataaat accccatctt ctggttcaca 600 taatgtaaca gggcatgttc gtaagctctc tggcacttgc aattgtgcat gctccacatt 660 aaatgcacat acttcaattt tatctaacaa ctcctctaac tggtagttag aaagcaattc 720 catattttcg agcatctcaa tttcacgcag tactgtaact tcacggcttg tcaaactacc 780 atgattaagt gtacgttcaa tatgttctat atattgaagg ccaatctgga tgttatcatt 840 cgataaacca tcctggttaa gacttcccat aaaatatcca tttacctgca taggtcgtat 900 tgacaccatc aactcaccca gtcttacttg agcttctcca cgaatagtct gattacgtat 960 ctcagacaag gtttcttgag gaatgtcaga caaaaaacta accccaggta aaatataagg 1020 cgttaaatct acaggcattc ctctccctcc attttaataa tttaattttg ctttagtaaa 1080 aaataaaaat acacaaaact atatttatag cattaattat cacttacaac aaaaagcttc 1140 tctttttgca tcaaagtgac attcgtcttt tctcataatc attgattctg ttataggttc 1200 tcgactcaga ggatgagttc caccagtttc aacaagttgc actaacgcat ccttatcata 1260 tagagagcat atctcagcac ctcgtgagtt tctcatgaac actccagtct caggtgtgtc 1320 cagcgttatc gggcatgtca aaaatgactc cgggcaagaa aagtgattag aatccgttcc 1380 aaatacacaa gaatttattt tttccattaa tattttatta cctgttttat tttctctgtg 1440 ttctgccatg acactctgaa aatagttatt aacactactt aaaaaatcga cacctccatt 1500 taattgcctt tccagagcca cagcccttct atccattcga tgctcacgcc ccaatagcct 1560 atccagtaag cctcctctca ccggttcaac tgaaaatcca tccagtagtt ggacatagtg 1620 aacagaatat tggccactac caatggatat tcttattcca ctttcaagtc tggctgcatc 1680 ctgcaaagac tgtactcttg caggagataa ttgagatata cttgggatac ttaaggtggt 1740 aacaggcata aaaacctcat tcagtaattc atatcagttt gcaggatgtt tcattaaata 1800 aaataaatgg taatgttcat ttcaattacc ctttataatg aagtttcctc tggtatcgtc 1860 ataaatgcat tcttcatgtt ttacaattat tgatgccgtt attggttccc gggtcagtgg 1920 gtggggtaag ccttcaccaa ccaaacgaga aaatgcagcg gcatcaaata aagtacatac 1980 atctgaacca tctgaattct tcacaaaaat acctttttca ggctgctcca gtgtaattgg 2040 acactgaata gcctcaagcg ggcactgaag tctctctgga caaacagaaa acttacattg 2100 agatattttg ttctgaatac tctcttgcga ttgtgcttca cctgagtccg aaagcatact 2160 tagcattctc tcaccaaggg ctcgaggacc actattaaat cccaaaagca ataactcaga 2220 aagcaatccg ccattaccgc cactggatga aaagcgccca ttagtagaat catacacaat 2280 actgacagtt tcaccaccga ctgtaatatc tccgcgccca ttggctacaa ttcgggcacg 2340 aacaacctcc accccaagat taaatgaatg tgatctaata tctgaggtta atggcataac 2400 aaagctccct attttaattt gaactccaga cttaaatagc tgtaacaaac atcccccata 2460 cgtgacaaca aaaaaccgga gccggactcc ggtttttgtg aagctgtcgg ctatttcatc 2520 ccgccaatat tttcccacgt cccgtcagca cgcaggattt gcagcggtct taccacacac 2580 tgtatctgct ttttatccgc atccagtatc accacctgcg tgattaccct gtcctgctcc 2640 gggataatac cattctcatc ggactccaga atgtctgccg gtcccagtcg cagctgtgct 2700 gtaagtaact ccccgttttc acggtcatca tgctttccgc aaccgcacag acgctgcata 2760 atttttttta atatgttcat gtcattctcc tgttctgcct gtatcactgc ccacttcatc 2820 cagcccctta acatcctgcc acggcccgtc accaaacctg acctgcaaat gctgaaaaaa 2880 accctgaacc cgtgtggcat ctttggggtc aagaaaggtc agtccggtga tgagtgcgcc 2940 atctgtatcc gggaaccagc catggctgtt tgtctcaata atgtttcccg gccccagacg 3000 gaaccgtatt tgcgtctccc ccgggtcgcc cttcggcccc tgaggtccgg ttgcccccac 3060 cgggccagcc gcacctgttt ctcctttcgg tccctgtggg cctgccgggc ctgccgggcc 3120 tgccggacca gcatcacctg ccggccccct ttcaccggtt gcccctgccg gaccggtgtc 3180 tccacgctct cctttatctc ccttcggccc ctgaggaccc gcgggacccg gttccccctt 3240 tggccgggag gcccaccacc gtggggattc ggtttacggc ctcttccgcc gctatcctgc 3300 tttgttcccg ctgactgtgc gctttctgct gactcccggg ctttttctgt tgcggtcgtt 3360 gcatcctggc tgcattaccg gctgcacttt ctgccgtctt ttttgacaac tcagcatctg 3420 ctgcactttg tgatgactca ctggcttttt gagcggccgc agaggccgag gacgaggacg 3480 cctcctctga ctgctttgca gcggctgcac tttctgccgc ctgccgggct gactccgatg 3540 catcccctgc tgaagtgtca gcatttgccg cgctctcttc tgcctgactg gctgatatgc 3600 cggcattcct cgcggacgtc tccgcctctc cggcattctt cttcgcctcc tcagcgtgac 3660 gcgccgcttc ttccaccatc agttcaaaac gacgcagtgc ctccggccgg acgtcatcct 3720 ccgacatggc accgagaaaa tcattcagcg tccccggttg agaatcttca tacacggtga 3780 tggtcccggc atgtgacggc gggaaccctt ccaccaacag aataacgctg tactgaccgt 3840 actcaacgtc catgctgtaa cgaccggctt catccggatt ttcagaggcc accgtgttca 3900 ccaccaccgt ggcgctgtta cgtctggctt tcagttgaat ggtgcagttc tctaccggtt 3960 ttcctgtgcc gtctttcagt acacctgaaa tctttactgc catattcacc ccacaaaaaa 4020 gcccgcctga accggcgggc tgtcataaca ctgtgttacc tggctaatca gaacttataa 4080 ccgacaccca cgatgaaacc gtcagtgcgc cagtcgccac tgccggagcc ttcataagca 4140 atatcaatgg ccacggattc ggtcgggtta aactgcacgc cagcccccca cgccagagac 4200 gtgttgctgt ggcgaccgtc atcacttccg gtcagcacat cgtgcgtttt ccccttgttg 4260 tcagttacgc gaagataatc cccggagaaa gtcgacacac ggctgtaagc cacacccgcc 4320 atcgcatacg cgctgaacca ttcattcacg cgcacagacg gccccgccat tacgctgaac 4380 cagcggttac gcacggaatc ttcatgccag cgggtatcgc tgtaacgggt aagctggcga 4440 ttcttgtctc ctgcatagct gaatgacgtc accagcccca gcgtgtccgt aaattcataa 4500 cggtatttca cgttaatccc gttaagatta tcgctaccgg gagcgctcgt ccgggcatga 4560 agataccccg cgctcagcgt ggcctgctgc tcagacgccc atgcaggcgc gccggatacg 4620 gccagacaga tggctgcgga caaaatggcg gcataaagtt tacgcataat tacctctcgc 4680 ttttctgcaa taaaaaaggc gccatttctg gcgcccgtat atgggttata aaattcagct 4740 gatactgata cctgctgtgg attttttcat caccacaacc agcagatcgc tgatactggt 4800 tgttggtgtc cagttattcg ctcctgatga agatacggtg aatgtcagtg tcagcgtccc 4860 ctgtccggca ggcatatcta taactgagga aaatacgccc tgagcatccg tcgtggactg 4920 attaaaaatc tcctgaccat tgcgggtcac tcttaaccgg caggttgaat accagtatga 4980 ctgttggtta ttactgttga aattctcatg cttaccaccg cggaataaca ctggcggtat 5040 catgacctgc cggtcaaact tctgatcatc actgattctt accgtgatgg tgccactggc 5100 ataagtgctc gtgcggggga aagacttgct gaccgttttg acaatatcgc cttcaatctg 5160 gttggctgac agtttcccct taatctgaca gttctcatta atcgtgacgt tgttgagcgt 5220 ccctgagttc gcattcacac tgccactgat atccgcattt ttcgccgtca gtcgcccgtc 5280 cggcgtcagg gaaaacgtcg ggggattgcc ggacgaggtg atactcaccg caaacagtcg 5340 cttcaggaac acgtcgttca tgaacagctg attcccctgc gccacaaata acggcgtgct 5400 gttgccgctc tccggattta tcatcgcgat acggtcagcc agcagcagta tgttgctcag 5460 tggctggcca tcagtatcct caatccctgc accaatcccg gccacatagg gaatgccgtc 5520 tttcgttttt tgaaccttca gcatgtacag cgcagccagg tcatcatttg tgtccttctg 5580 cacgcgctgt atctgctgta tagtggcgct ctggttctcc agcgttttac tgaccgtctg 5640 tgtgatttca ttgcgggttt ccgtgatggt ggtcttcatc tccgccatct catccgcaag 5700 ctggctgttg tctatcagct cccatagccc ctgagccaga tgcagttttc ctattttttc 5760 ccggaaaaat tccagatacc cttcaccatc attgctgggc tgcccgctga cttccacaaa 5820 cgcagatttc cccaccaggt tgacgctgcg cacgtaaaac cagaaatccg tccccggctt 5880 aatccggctt ccctggacag tccactgact gccgctcccc agataacggg cagatttttc 5940 cacctgtgcc gtgttcgtga tgcgtttttc cgaaaaccag aactcaaact gcaccgtcgg 6000 gtcatacacc gccagcaccg gtaccgccgt tatctgaaaa taccccggcg tcagttcaat 6060 ggtggcgggt tttgctggcg cgttaatccg gaaggtggtg atggccggtt ccccctgctg 6120 gccataactg ttaattgccc tgactgtcag ggtgtattcc ccgagcggca gaccactgaa 6180 acgatgctct gtatccgcag tgatggcggt ggtcaccaga cggctgtcct gaccgcttcc 6240 actggtcagg cgcagactga agcgcacgcc cttcaccacc cgcggcgtgt cccatttcgc 6300 ctgcgccaga tactggctgt cagctgcact cacctccacc gtcaggtgct gcactgccgg 6360 agggatgacg ctgttcaggg tgccgctctg gtcgccgtca aagtgcgccc cgttatccac 6420 gatggcttct ttttccggta cgtgctgcac tgccgtgatg gcaaaggtgc cgtccgtgtt 6480 ttcccggatg gagacacagc ggaacaggcg acgacgcagt gacggcaggg agagccccca 6540 cacaccgtat gtctccacgc catccggcag ggtgctgacc tgtatccggt ccggcgcggg 6600 gtgtgcagtg atggccacgc tcaccggctt accgctgccg ttaatcaggt tcaccgtggc 6660 ggcaccggtc tccggcaggg tcacctcacg gtccagtgtc agggtgcggc tggcggcatc 6720 gatggacagg atacgtccgc cggtcatggt cccggcatag tcgttatcac agatttcaat 6780 aatgtcaccg ggtgtgtgac gcagcccctg tgacccgagc gtgaaatcca ccgtctgcgt 6840 ttccagcagt ccggtcttta tcacccacag cccggcacgg tgggcctgac cgcgactggt 6900 acagccgaac gcatccatct tcagcaggtt gcgcccgtag cgcagtatgg cttccgggtc 6960 ttccaccagt tccgtggagg tctgccagcc gttctgcggg tcggtgtaat tcacctccac 7020 cgccgtgtgg cggtccttca gggcgctgaa gctgtagcga aaccccacgc cgttatcatc 7080 caccaccaca tcactgttgg tgtacggcca caccacatcc gacggactgt cctgaacgaa 7140 cgtcagcgtc tggccgttcc ataccggcat acagcgcatc gccgagcaga aatcactgag 7200 aacgtcccac gccttacgct gttgtgacag gtacgcatta aaggtcatcc gcggctctgt 7260 gcccccgaaa ccatcaggga ccatctggtc gcagtactgc gcaatggcat acagcgccca 7320 cttgtccaca tccgccgccc ccaggcgttt tcccatgccg tagcgcgggt gagtcagcat 7380 gtcccacagg caccaggccg ggttgttgct gtatgccggt ttcaggctgc cgtcccagat 7440 gccgctgtac gtgcgttttt ccgggtcata gtttgacggc acctggatga tgcgaccgcg 7500 gatatggtag ttcaccgtca tctgctgacc gccaaactgc tccgcatcca cctgcagccc 7560 cacaatggcc gtgttcgggt agcactgttt cacatcgatg atttcggtgt atgacgacca 7620 cagcgttctg ttctgcagct ggtccgtggt gctgtccgcc gtctccctga ccatccggat 7680 gttaaagggc cggggcggca gattatccag aatcaccgac gccaggaact gcgaggtggt 7740 cttgccgtta atggtgacat ccttttccgt cacccagtta ccgttacgct gcaactgaat 7800 cagcagtcgg acagaagagt gattacggtc gccctttgag gtggtctcca acagtgactg 7860 caccccgaag gtgacccgca ggcggtcaat gttcgcggac gtaatggtgc gcgtcaccgg 7920 ctttgccttc gtcacttcca cgcccagtgc ggtttcagct ccggaggact caaagccttc 7980 cggtggtgtc tgctcctgct ccccggcacg ccagaccgca gtcacaccgt gtatcacggg 8040 attaccgtcc gtgtccgtca gcggggtttt gttcaccaga atactctgca gccccttcac 8100 cggaccttca atcggccctt caccaatggc gtcaatcacg ctcatcatct gcgtggactt 8160 aagattgtcc tttgcctcta ccggcgtgtg ccccttgccg ccccctttac ccactctgtc 8220 cccctctcct gtctgatgtc tgaatctgtt tatgccagaa aacaacaggc accccggagg 8280 gtgcctgtgt catgacggaa taaaatttct gaaactcttc acatttccgg caattgcctg 8340 tagccgcaat aatgacgctg cattactttt ttgatgcctg aaaaataact ccataacgtt 8400 aatcttcatc gttctctccc gcagctccgc taactctgcg ggattttttt attttcatcc 8460 ccgcccgata accaccactt tcccgtctcc gccctcatca cgggtgctga tgtcctggga 8520 tatccgtcgt gaaccaacca gcatttcacc ataaggcacc ggcatcgggt tcccctgggc 8580 aatcatgtta tccagtgacg aaaaatacgt gttctgttta ccgttatccg tcgccctgta 8640 ctccggtgtt tttgccttcg gtgccagcat ctgggccaca ccgcccagta tcatgctggc 8700 acccagtgag aacagcatcg tggtggcagt cagccctccg gcactcaggg ctgcgcccca 8760 caacgccatc gttgcgccgg cggtgaagaa agagcccacg atggctgccg cccccagcac 8820 aatctgcagt ccaccctttc cggctccggc cagtcgcggc acaatatgga tgaccgcccc 8880 ctcacccaga ggttcgtgaa gacgggcgta caccgcctcc ggtgccgtgt cctcaccgcg 8940 aatacgtatc tggtaccagc cttcgttcat ctgacggcgg aatcccggca tctgcagcga 9000 cagggcacgg atggcttccg ctgccgtgtt cacgtacagg ctgaggcggc ggccaaatcg 9060 ttgcaaatcc ccgtgaaggc agatgcgtgc cagtggcggt gacgccagac agaatgcgtt 9120 cgtcgttgcc atttttcaga atacctctcc cgtttactca gttgttcagg cagatggtga 9180 agcagttcac cgttgccgca gtatatggcg gcatgattgg ccaccgatgc gccaaagcag 9240 cacagcagga tatcgcccgc ctgtgcagag gacaggggca cccggtaaaa accagtcgcc 9300 gccatattgt ccaggtaaag gttctgaccg ttgcgccacc agtcatcctc acgctcaaaa 9360 tccggcagcg ttatccccgc cagatggtat gcatcccgga acagggtgta acagtccgtc 9420 accccgtgct caaaacgacg cccggtcagg tgcggcacac agcggaattt atgaatttcc 9480 ccccggcaga ccagccacca gggcagggca ctctttatct gcagccgccg gtcggcctcg 9540 ctcagccagg gcagaccacc aggtggctgt gaaccagcgc cacaatctcc ccctgcatct 9600 ctgcctgcag ccagtcttcc ggcgcaatac gaaaatacgc ctccggctct gcggagatat 9660 tcacgcaggg ctggtaccgt tcgccctccg gggtgcctat cacgaagccg cacgactccg 9720 caggcgcaca ccgccgggca tgcaccagaa tcgctgattc agtctgtgtc ataaaacagg 9780 atttactgcg aaagtttatt gatggaaagg aaaccgccaa aattagccac catgccgcgc 9840 atctcacacc cgcgcatgca cttgctgcat ctgtccttac ggatatccgt ggtggggttg 9900 tcgaactcat ccgccaccgc aggaccgtta tacccgcatt catctccccg gtaatcccac 9960 atacaggtat tcgccagcat aatgcgaccg ggaaacagcg ctccgtccgt ctccgtcggt 1002 0 gtcgccagca caaacgaggc cgtcatggcc gtcagcgatg acatctgctc caccacccac 1008 0 cggtccgtca gctcctgctc agggtctgcc tcaggattgc ctgccacaaa attcaccgca 1014 0 tccagaaaac gggcatacac ccggcggcgg accaccgtgg cccccaccag gctctgcagg 1020 0 tcctccgcca tcccggtgac cagaccaaac agattcgaca ccgtcagcga cggtctggca 1026 0 ctgctgccct tcccgttcat ctcaaagcca ctgccgtcaa tcgggtatgc ctgatattgc 1032 0 cgcccctgcc aggtaaccgc ctcccctttt tcattcagct cattgcagaa aaaataccgc 1038 0 tcaccgccct gcgccgtcag gtcgatttcc cagagtacca cccgcggtga ctgctctgat 1044 0 ttaaccgact cgttcagact ttcttcgtga atatcctgca tcagttcacc acctgcttaa 1050 0 actccgcgct gaactcaacg cgcaacatcc cgacccgcgc agaccacccg gcacaggtca 1056 0 cctttatctg ccggtatgca tagggtggct tccacaaaaa tgccttccag cctccgtgct 1062 0 ctgccaggaa cgcttccaga tgccgggcct cctcccgggt cacggaaagc gtcacacggt 1068 0 atgttttcag gtcagcattc agccctgccg ccatacgctg tgagtacccg tcaccaaaac 1074 0 gcacttcacg caccgatggc tgcgagttca cctccatatc cggcttcact ttccagcgaa 1080 0 aggttttcat cgcccgctcc ccgataacat accgccatca cgcaactgca gccggagctc 1086 0 atcctgcgcc cccttgcggg ccatgtcata caccgccttc atcagctgcg gccccgcctg 1092 0 tccgttggtg ccgtcgttct gaatcaccac gtgattgttc tgattaaaat taataccttc 1098 0 cgcccgccgc atctgcgccg gacttccggc accacccaca taaccacctt ccgcatagcc 1104 0 gcgcatcaga cggtaaagat tccccacacc tatccggctg gttgcctctt tcgtgaaaac 1110 0 aaactccccg cggtgaacta tccccgcagg ctcatatttg ccgcccgtcc ccgtaaatcc 1116 0 tccggtcgcg aaatggaagt tcgccgccgc agcctgaatg gccgtccccg aggaagcaga 1122 0 tgcaccacca ccgaaagcac cgccaatggc gctgccgata cgcccgacaa tgcccaccat 1128 0 ggcctgttta agcaggattt ctgtcatcat ggacagcacc gaacgggtga atccccgcca 1134 0 gtctgcctct gcaccggtca gcatcgccgc catattctgt gcaataccgt caaaggtctg 1140 0 cgtggcagca cttttaacct gcgaaaaact gtccgtcgca ctttccgccc actcgcccca 1146 0 gccggacttc agcccggcca tccagcttcc acgaagctgc tcctccgcag acctggtgtt 1152 0 cttcagtgcc gatgtggcct tcgccagcgc agccggatta tcaccgtaca cgtcccgaag 1158 0 acgctgcgct tcagactccc gctgcgcctg acggtcagtg agaccgcggg cttttgcgct 1164 0 gatggcggcc tgcttcgcgc tctgctgctc ttcaaaccgc accgcctgct gtgccagctc 1170 0 attcaggcgt ttctggtatt caaccttgtc gcccagctca gccagctggc gtttgtactc 1176 0 cagcgtctcg tctttatgcg ccagcaggga tttttcctgc tcagataact gtcgtttcgt 1182 0 ggcagcctct ttcaggaccg catactgact ttccgccttc cataaatcac ggcgctgccg 1188 0 gctgattttc tcattcgcac cgctgtgttt ttccagcgtc ctgagctcag cttcaagggc 1194 0 aagcagagcc tctcttgcct gctcctcttc cctctccccg gcagagcgcg ttttcggtga 1200 0 tgtatgcttt ttacctgtca gctcttcagc cagacggctg acggcttcct gctgccccgg 1206 0 acctttgctg acgcctgttg cacgcgagcg gttgatgtac cccatttccc cctggcgtat 1212 0 acgcgcatcc cgttccgcaa tggattttct cagcgccagt tcatcgcgtt ttgttttctc 1218 0 aataaatacg cggttctctt ctgccagttc accaaacaac gcaccaacgc cgggcacatt 1224 0 ctttgtcgtt tcccaggctg actgaataaa ttcagccagc gccagatccc cctgcacaag 1230 0 cagcagcttc acttgttcaa cggttccggc caccacgtca gtgatcagac tgagtgcccc 1236 0 cagtgtatga tcacctatcc atgcccatgc gtcagaagtc caggttttaa catcgtccca 1242 0 gattttttcc accggcgtgg ccgctttatc aagttgctcc agacgtgcat tcatgacatc 1248 0 cgcaaacagg gacatcgcct ccgtcaccgc aacctgttta cctttcgtgc gctcaagctc 1254 0 atcaatatgg cgtaactggg aaacgctcag gaagttatac tgctgattca gggaggccag 1260 0 cgccttcacc ggatctgctg caatcccttc aaaggctttt tccaccttcc cggcatcgtc 1266 0 ccccaccgtc tgcagccatc tctgagaggt ttcccccatg atccgtagct gcccggcggt 1272 0 atatttcccg ctttctgcca gacgggccag attttctgcc gcctgtctga taccaccacc 1278 0 ggcttcatcg ctgatcaccc cggccatttt ccacaattct gccgttgtgg tggcagccgc 1284 0 ccctccggtc aggatcagtg aacgcaataa ggcccggtca gcctgctctg cctgccaggc 1290 0 ggcggcagca agcgcggcca gtacggcaac cccgccacct gccgccacac gggccaccga 1296 0 cataaatcgt cccagctcac cggcattccg ggcattttca gccagtgcat ttgccgtatc 1302 0 tgacagcgac tcctctgatg attcagaggc atccctgatc ccgagaagtt cctccttcag 1308 0 cagggtaagc aggctgagcg gtccaccgaa tgaatcgctg atctgccccc cctgctgcag 1314 0 catgataagg aagggattct gaccaccggc aagctgagtg acaatatccg tgaactgtgc 1320 0 gggcagtgtg cgcatggcag ccttatactg tccgactgat atcccggctt tttgtgccgc 1326 0 cagcgcctgt cggctcagcc cctgttcaac agtactggcg gtttttctgg catccgcctc 1332 0 cagactggaa aaatgacggc gtacccgggc catctgttca tcaaaccggg ccgcatccag 1338 0 actcaaatca ataaccagat cacccgctgg ctgggacata tctcacacct ccggaaatcc 1344 0 ccgctgaagc catcattaat gcaacatcat cctcgctgac atccaccaca tccgcagaag 1350 0 gtgaaatatc gcgccctccg tcccctccga accggacgcc tccggcaact cctgtcgctt 1356 0 tctgcatcag catttcttcc tcgtccggca tctccgtctg ctcttcctca cacgctggag 1362 0 caagcagact gaaatccgcc ggatgcatat ccggatcgcc aaaaaacagg ctgagtacgg 1368 0 cgtacatcag cccggaaaaa tgagcgtcca gttgggtatc ctgaaaataa tgcgtgcagt 1374 0 aaaaacgtcg ccagtcggca tattcggtgg atgtcatccc ggcaagcatg gcgcgccagt 1380 0 cgggtctccc catctctcgc gccagtttca ggacaaagtt cagctcgcct tcgaatgctt 1386 0 ttttgatgtt accgactcag tcgcttctgc tttaccggtt tgttcaggat cggcatcgtg 1392 0 ccggttatcc agcatacctg aaagataaag cacccggttc gttgcctgat tcagtgcatc 1398 0 agcaggccat cccagcatca cttcacggcg gatctgctgc atctctgtct ccggagaggc 1404 0 cagagtgcct ttgagggaat gggaatgcca tagcgacatc gccacaagca gggatgccgt 1410 0 ttccagatat cgctggttaa tgtgcacgac atcatgcttc gttgtctcct gttgttctgc 1416 0 gtctgaaaca aactttatat aatcaaaccg ctgcagcgca gacaattcgg aaagcgtgac 1422 0 ggacacaccg ttatattcaa attgttctgt tttcagaaac atgtattacc tccgtttacc 1428 0 ctgcagcgcc cgcttcagta acggtgactt cagccactgc ggcgaactga ccatttccgc 1434 0 tcaccacagg gatctgcacc ttacctgtcg ccacgccgtt taccgtaatt gtcatatctt 1440 0 tcacactaat ggtggctttc gacggatcgg cggaaaccgc tctgaacgtc ttgtcggttg 1446 0 cactttccgg ctcaaaagaa acagtcaggg tggttgtttt cccttttgcc accgtaccgg 1452 0 atgtcggtgt caccttaatt gcagtggccg gcgtaatttc gctgcgttct tccgccacgg 1458 0 aaggtttgcc cacgttagtg actttcaccg tgcgggtgat cacttctttc gccgtcacgg 1464 0 ccttaccgat actgctgacc cagccacgga acacatccac cgtgccattt gggaaacgga 1470 0 ttttataggc ccgcacatcc ccgctttcaa accagcctat aagccctttc tgaccttctt 1476 0 ctcccggttt ccaggccagc gtaaaactgg tatctcctgc agacttctgc ccctgcccgg 1482 0 tcgcggtcca gtccgcgtct tcatcatcca ggtagttatc atcgtagggt tctgccgtca 1488 0 tctcgcccgg cgtcagatcc ttcaccttag ccagtcgctg ccagtcatcg tctgacaacg 1494 0 ggtttgcata agcatcaccc ttgccgttgt aaacccacag agtggtaccg gcacctttta 1500 0 ccggctcaag gggatttggt gttgccatat cgtcctcaca tctcgtatgt aatggaataa 1506 0 gtcagatccg cagaactcca taacgccata tcgtcatcac gacgatactc atagccctgc 1512 0 gtaaccatcg tcgtaatcag gtctgccagt gccgggatcg cagtcaccgc cggataaatc 1518 0 cggctttcca tccactgatc aagctccgaa tccggtacct gtgccggtaa aaacacctca 1524 0 atatgcagtg tggcccgcca ggtatctgca tccagctctt caccggtata ctctgcatcc 1530 0 gtcagataaa ccgcgacggc cggaaaatcc tcttcgtcaa aaacaacggg gcgaccatca 1536 0 aacagcgtcg ccccgtgttc atgcagctcc agtgcatcca gcactgccgc acggatatca 1542 0 gtatgtttca tcgttttatc gcaatcctaa gttgttgttt cagcgcgtat gccagttctc 1548 0 cgggcagacg ttcacgccgg atacggtcaa tattctcatc aaacgcctgt ttcagtgggg 1554 0 ccgccatcgg gattttcacc acatcaatgg ggtaacggtt tttcccggcc acacgctgca 1560 0 tgacatgcca gcgaccattt tttaatcgct ggataaatgc ccgctgatac cgatgctgac 1566 0 cagctttaag tatgctgtcc ggacgacggc ccagcatcct gatccccagc ttaatcacag 1572 0 ggagatcacc gcgtttaacg ataattctgg cattcggatt tctgaccgtg gcccgtttca 1578 0 gtctggaccg ttcctttacc agtttccggc gtacctttgt ctcccgggca acctgtgatg 1584 0 aagactgatt aatcgccgtt gtggccacgc ggttaatggc cattgctgaa gccgccggaa 1590 0 tggcgttttt acgaacccgg ctcagatttt caatcgcctg atcaagccct tttatcgcca 1596 0 taattcaccc tgcgtttatc gtcgccggtt aactgccggt ggttgcccac ggttgagcca 1602 0 gagataacaa ctccctccgt catccggaga aacacggtcc acccagaaca tctcgccgtt 1608 0 aatggtcagc gtgtcaccac gccgcagttg ccgcacatca tcagtccgga caaacaggga 1614 0 cgggctggag ccttcaacgc gcacgccctg tccggcatag ctgatatttt cagggtcatc 1620 0 aaaaacacca cgtattactg cgccggaccg ctcaccggat gtcatggtgg ctgacgttcc 1626 0 catgtacccg cgtatcgttt catcggcgcg ggcaatggca gcatcgaaca ggttatcgaa 1632 0 atcagccaca gcgcctcccg ttattgcatt ctggccaggc cgcgctctgt catttcggct 1638 0 gccacaccgg cagagacacg aaacgccgtt cccggcagca caaatgccac aggttcatcc 1644 0 cgcgtgacgt gaagtgcatc agtatgcagc ttcaccagtg ccacgaccgt gaccagttca 1650 0 gacgtatcca gaatcacggt atccggctgc gctgatccca cctcattttc atgtccggtc 1656 0 agcacatttt cccggctgag aggggtgtcc tgaccggcag tttcatccgt gtcatcaagc 1662 0 tcctcttcca gctctgccac acggagcgcc agttcttctt tcgtccccgt caggctgaca 1668 0 tcacggttca gttgttcacc cagcgagcgg agacgggcaa tcagttcatc tttcgtcatg 1674 0 gactcctcca cagaaaaaca atggccccga agggccatga ttacgccagt tgtacggaca 1680 0 cgaactcatc agggtcagcc agcagcatca gcggtgctga ctgaatcatg gtgaactcac 1686 0 gcgccggatc gccggtggtc acccagtttt tcgggtaacg ggcagaggcg ttaatgcctt 1692 0 cgcgctgtgc gtccgcatcc tgaatgcagc cataggtgcg cagaccgcgt gcctgagtgt 1698 0 tccccagcac catcgtgttg tccggcagga agttcttttt gacgccgttt tccacgtact 1704 0 gtccggaata cacgacgatg gccacatcgc catacattcc cttataagac accgctttgc 1710 0 ccaggtcttt taccgctgtc tccagttcgg aatgagagcc gcgacgggta tccagcttct 1716 0 ccctgacggc tttgaaggaa cggaacagcg cccagccttt cgggtcaaac acgatgatat 1722 0 tcaccacgcc gctggcgttc agcgcgtagg cttcgatatc gtcggtcggg tcatacgtgg 1728 0 acttgtcacg cttgctccac tccgtgccgc cggactgcgt gatgttgttc gccgcactgc 1734 0 ggcccatatc cacctcaacc ggatcgaagg cttcaccggt catggtgtat ttgcccttga 1740 0 gcacggcaga aactgcctgc atctcttcga cctgagcaat ggccagctct tcgtcacgca 1746 0 tgttctgcat gatgatgcga cggcggcggt aagccgggtc cgccagattc tgcggatctt 1752 0 catccggcag gcgacgcagg gtcatctgcg gattcacttc atgcttcggc ttgacatatc 1758 0 ccggcgtaaa ttcagaggtg gagccgccac gggaacggat aacctcacca gaaacaatcg 1764 0 gcgaaacgta cagcgccatg tttaccagtc ccggaatttg tgagagatag actttctccg 1770 0 tggtgaaggg atagctctca cggaaaaaga gacgcagaaa cagcggatca aacttaaatt 1776 0 tctgctcatt tgccgccagc agttgggcgg ttgtgtacat cgacataaaa aaatcccgta 1782 0 aaaaaagccg cacaggcggc ctttagtgat gaagggtcag gttaaacgat gctgattgcc 1788 0 gttccggcaa acgcggtccg ttttttcgtc tcgtcgctgg cagcctccgg ccagagcaca 1794 0 tcctcataac ggaacgtgcc ggacttgtag aacgtcagcg tggtgctggt ctggtcagca 1800 0 gcaaccgcaa gaatgccaac ggcagcaccg tcggtggtgc catcccacgc aaccagctta 1806 0 cggctggagg tgtccagcat cagcggggtc attgcaggcg ctttcgcact caatccgccg 1812 0 ggcgcggttg cggtatgagc cgggtcactg ttgcccagcg gctggtaatg ggtaaaggtt 1818 0 tctttgctcg tcataaacat cccttacact ggtgtgttca gcaaatcgtt aacggcatca 1824 0 gatgccgggt tacctgcagc cagcggtgcc ggtgccccct gcatcagacg atccagcgca 1830 0 gtatcactgc gcgcctgtgc actctgtggt gctgcggcca gaatgcggcg ggccgtttcc 1836 0 acggtcatac cgggggtttc tgccagcacg cgggcctgtt cttcgcgtcc gtgagcctcc 1842 0 tcacagttga ggatccccat aatgcggctg ttttctgccg caaccgcagc ggtgatctgc 1848 0 gcgttcacgt ccggctgcgc cgcgctggcg ttttcgccct ccgtcgctgg caccacgcca 1854 0 gtaacgtcag cctgcgaagc agtggctgaa acagttgttg attgagtctc tttggtcatt 1860 0 cgccctcctg agagacggga tttacgtgca tccagtgcat cacgcataac ggtgatcgca 1866 0 tcggtgctgt tgacaagttc atcagccagt ccggcatcaa tggcctcctg accgctgtac 1872 0 actgcagcct cggtatccag cacagcctgc acggacaggc cggtatatgc cgacaccttc 1878 0 tgcgcaaaca tccggcgggt tgcatccatc cgggactgca gtgtttcccg gacatcaccc 1884 0 ggtagatggc tgtaggggtt gccatccacc ttatggctgc cgctgtaaat cagcgtgatt 1890 0 tccacgccct gtttctccag ggcagcaccg taattactgt gagccatcat gacgccgatg 1896 0 gagcctgtcc gggcggtctg cgtgaccaga cgccgggagg cggcgctggc aagcagctga 1902 0 cctgcactgc agttcatgtc gttggccagc gcccataccg gttttatgtc tcgcacacgg 1908 0 gcgatgatgt cagcacagtc aaatgctccc gccaccatcc cgcccggtgt gtccatatcg 1914 0 agcagaatgc cgtccaccat cggatcgctg gcagcctgtt gcagacgggc gataatgccg 1920 0 ttgtaaccgg tcattcccga atacggctgc agcgcccgcg tccggctgac cagcgtaccg 1926 0 gacaccggca gcacggcgat gccgttcatg acctgataac tccgggcctg tcgtggtccg 1932 0 tcatcatcac cggataacgc cagcgccgcg ggtgcctctc cggcagtcag gctgtcgccg 1938 0 gatactgcat ccgtcaggcg gctgatccca agctggcctg caagcgcaca aaagaaaacc 1944 0 cgcgcatagg cgggttcaag catcagcggc tcattaaaag ccatgctggc aatatgcggg 1950 0 agattacgca gctctgctgt cactcttctc ctcctctgtt gattgtcgca gcccggattc 1956 0 aaatgccgca gccgcccagg cgggcggttt aagaccagct gcgcggcgct ccatcgtttc 1962 0 acggacctgc tgggcaaaaa tttcctgata gtcgtcaccg cgtttcgcgc actctttctc 1968 0 gtaggtgctc agtccggctt ctatcagcat caccgcttcc tgaacttctt tcagaccatc 1974 0 gatggccata cgaccggagc ctatccagtc gcagttcccc caggcactgc gggcttcctg 1980 0 aaagctgaag cgcgcttttg aaggtaacgt caccacgcgg cgaacgatgg cctcttccag 1986 0 ccagcacaga aacatctggc tcgcctgacg ggatgcgacg aattttcgcc gccccataaa 1992 0 gtacgcccac gactcgttcg cactggcccg tgccgtggag tagctcatct gggcgtaatt 1998 0 ccgggaaagc tgctcatacg agacacccag cccggcagcg atataccgca gcagtgactg 2004 0 ctcaaacacg gagtagccgt tatccgtgtc ctgagccgtc tgcaggttca gtgagtcccc 2010 0 cggcatcagg tgcggcactt ttgcgcctcc cagacggacc ggtgctgcgg cgtaatacgc 2016 0 ggcaatttca ccaatccagc cggtcagcct ttcccgctgc tcctgactgt tcgcgcccag 2022 0 aataaaatcc atcgctgact gcgtatccag ctcactctca atggtggcgg catacatcgc 2028 0 cttcacaatg gcgctctgca gctgcgtgtt ctgcagcgtg tcgagcatct tcatctgctc 2034 0 catcacgctg taaaacacat ttgcaccgcg ggtctgcccg tcctccacgg gttcaaagac 2040 0 gtgaatgaac gaagcacgac cgccgggtaa ctcgcggggt atccatgtcc atttctgcgg 2046 0 catccagcca ggatacccgt cctcgctgac gtaatatccc agcgccgcac cgctgtcatt 2052 0 aatctgcaca ccggcacggc agttccggct gtcgctggta ttgttcgggt tgctgatgcg 2058 0 cttcgggctg accatccgga actgtgtccg gaacagtcgc gagggacggg tatcccaggt 2064 0 ggcctgaacg aacagttcac cgttaaaggc gtgcatggcc acaccttccc gaatcatcat 2070 0 ggtaaacgtg cgttttcgct caacgtcaat gcagcaacag tcatcttcgg caaactcttt 2076 0 ccatgccgct tcaacctcgc gggaaaaggc acgggcttct tcctccccga tgcccagata 2082 0 gcgccagctt gggcgatgac tgagccggaa aaaagacccg acgatatgat cctgatgcaa 2088 0 ctggatggcg ttggcggcat agccgttatt gcgtaccaga tcgtctgcgc gggcattgcc 2094 0 acgggtaaag ttgggcagca gggctgcatc cacactttca cccggtgggt tccacgcccg 2100 0 caactgccca ccaaatccgc tgccaccgcc gtgataaccg gcatattcac gcagcgatgt 2106 0 catgccgtcc ggccccagaa gggtgggaat ggtggacatt ttcatacata aaatcctgca 2112 0 ggtcccctgc gtcgctgtgt catgccggtc tgcacttcca gctcagcaat gtattttttc 2118 0 aggtcagaca cggaagtggt cgtaaactcc actcgccgtc cgtctttctg taccgttgcc 2124 0 acccgttttc ctgtcatcag gtcatgcagt gccgcacggg cagcggcaag ttcttcctgt 2130 0 cgcgtcattc atcctctccg gataaggcac gggcgtattc tgccagtgtt ttcttgttgg 2136 0 ttgctgcacc atcctcttcc tgcaggctcg ccagcagtgc actgagatcc agctgccagc 2142 0 gggaaatact gatgcgcagc gccgccagcg cataaacgaa gcagtcgagc gcctcattgc 2148 0 gtcgcttttt gctgtcccac agtatttttt tcctgccatc cacccatttt tcgacctgct 2154 0 cttcagcagt cagttgctgc gcttcggtaa gatcaaaaat atccgggtta ttcgggaagt 2160 0 gaacggcacc gggaagcggt tcatcccctt ccggcgtcag tgtgaagcgg ttataaatct 2166 0 gctctttcgc ggtatccgta ccgatttcgg taaggtaaac cccgtttttg tttcgcttac 2172 0 gtggcatgct ggccaccggc tttccgtaga cggatgcccc tttaatgggg atcacccgga 2178 0 acagcccatg ttttttcgag cgttcataca caatggtcgg gtcaatcccg ccagtatccc 2184 0 agcagatacg ggataccgac atttctgcac cattccggcg ggtataggtt ttattgatgg 2190 0 cctcatccac acgcagcagc gtctgttcat cgtcgtggcg gcccataata atctgccggt 2196 0 caatcagcca gctttcctca cccggccccc atccccatac gcgcatttcg tagcggtcca 2202 0 gctgggagtc gataccggcg gtcaggtaag ccacacgatc aggaacggac gctgaataat 2208 0 gctctttccg ctctgccatc acttcagcat ccggacgttc gccgattttc gcttcccacg 2214 0 tctcaccgag cgtggtgttc acgaaggttt tacgttttcc cgtatcccct ttcgtcttca 2220 0 tccagtcttt gacaatctgc acccaggtgg tgaacgggct gtacgccgtc cagatgtgaa 2226 0 aggtcacact gtcaggcggt tcaatctctt caccggatga cgaaaaccag agaatgccat 2232 0 cacgggtcca gatcccggtc ttttcgcaga tataacgggc atcagtaaag tccagctcct 2238 0 gctggcggat gacgcaggca ttatgctcgc agagataaaa cacgctggag gggtcatccg 2244 0 gcgtccattt gaggccaaac ggcgtctctt tgtcgccaaa tttaagatac tgctcctccc 2250 0 cgcagtgcgg gcaggcaaca tgaaaacgca taaaatgcgg ggattcactg gctgcacgct 2256 0 caatctggca ggtgcctctc actttgggcg tggagccacg gatggacttt ggccagaccg 2262 0 agccttcaat acgcttgtca cccaggaacg tcggagagcc ttcctgttca atatcctcat 2268 0 caaaggcagc aagttcatca taacccgcca catcaaccga cttttcacgg tagttttttg 2274 0 ccgctttacc gcccaggcac cagaagccac gaccattggt gaaacgcttc atagtgagcg 2280 0 tgttatcccg gtgctttttg ccataccacg gggccagaga cagcagcgac ggaatatcgc 2286 0 ggatggtagg ctcgacgtgg gttttcataa agttctcggc atcaccatcc gtcggcaacc 2292 0 agataagggt gttacgctgc ttatgctcta tgaagtaggc ataaacaccc agcagcattt 2298 0 ttgaataacc aacacgggca gacttcacca cattcacctc gcggatgtag tcgctgccca 2304 0 tcgcattcat gatagcccgc tgaaagggta gtgtttccca gcgcccttcc tggtatgcgg 2310 0 attctttcgg gagatagtaa ctggcatccg cccattcaac ggcagtctgt ggctccggcc 2316 0 tgaacagggc tcgcagcccg gcgcgtacat cacgccgcag aatatcaatc tgactgttcg 2322 0 atatattcac tcagcaaccc cggtatcagt tcatccagcg cggctgcttt gttcatggct 2328 0 ttgataatat cccgtttcag gaaatcaaca tgtcggtttt ccagttccgg aaaacgccgc 2334 0 tgtactgaga gagggatccc gtcaagaata ctggcaattt cacctgcgat ccgtgacagc 2340 0 acgaaagtac agaatgcggt ttccaccact tctgcggagt ctctggcatt cttcagctcc 2346 0 tgggcgtcag cctgcgcacg cgtaagtcga tggcattcgt actcaatagt cccaggctgg 2352 0 agatctgcct cgctggcagc cctgtaatcc tcaacctctt tacggagttt ttcattttcg 2358 0 atatcagctt ccctctgcgc ataccactga attgccgtgg cggtatcaaa tacagattca 2364 0 acgcccttac cacctccgga gacgcaaggg agcccctgag actgccagcg ttcaatcgtt 2370 0 cgcggatcca cgttgaaaat ttcggcaagt ttctttttat taaccttcat gaaacagtct 2376 0 cacaacaaat acagggtccg acatgaaagt gcccgaaaat gactttttca ggcgttttca 2382 0 tgtcggacct ttacggattc gatattagaa aaaacaaata gttatgttcg agaagtaccg 2388 0 acatgatttt ccccggaaaa ttttcataaa tagcgaaaac ccgcgaggtc gccgccccgt 2394 0 aaccggtcgg atcgccggaa aggacccgca aaatgataat aattatcatc tacatgtcac 2400 0 aacgtgcatc tacgccatca aaccacgtca aataatcaat tatgacgcag gtatcgtatt 2406 0 aattgatctg catcaaatta acgtaaaagc aacttcagat aatacaaatc agcaacactg 2412 0 aatatggggc aacattatgt catcaaagaa cagaacccgc agaacaacaa cccgcaacat 2418 0 ccgatttcca aaccagatga ttgaacaaat taacatcgct cttgatctga aaggttcagg 2424 0 aaatttttca gcgtgggtta ttgaagcctg cagaagaaga ttaattaatg aaaaatattc 2430 0 tcaatttgta cccaacaaag acaaacacga ccagagaacc tgttcagaca ggtttactta 2436 0 aacgacttat atatgacaca aaaagcgacc actaaagtcg ctttttctta tggtaacagg 2442 0 caataacgct ctcagatatt ttttagcatt tttttgaccg cgcgtttccg gacgtattct 2448 0 gttctcctgt ccctttatat cgtcggaata cccgccgctc ttcaaatccc attcccaact 2454 0 cagaatgtag tctgttgacc gcttgtttta tttcggtcag gttcaccggt gaaaccggag 2460 0 tccggcgcgc cttacgcaaa cactctgctc gtttctgtgc cgccactttt cttttctggt 2466 0 catcacttag ctgtaccatc acttttgccc atcgttcagc tgctctccgg tacagtcctt 2472 0 ttttctccag acattctgcc aggtgatcat gtagcataag taacctccgt ttatctacag 2478 0 actgccatcc tgaatttacc gtccttaata agacaacaat aaaaaactaa ttatataaaa 2484 0 acaataaaaa taatatacaa aaaaactaaa caacaaagaa aagcaaatca tatctggcat 2490 0 tttaattgaa agagcaatta ccgaacaaaa gacgctgact atatactcaa aaccaaacaa 2496 0 caattctgcc aatcaggtat catggcaaca cacggaatta ccatgttttt gccttctctg 2502 0 cccatacaat acgggcatat acttcatact ctattgtaat atttctatcc atgtgcccca 2508 0 ctccatttac ctgtaaataa tattcaaaat atttatcaca gaaatcgttt ttggccatga 2514 0 actgagcaca ctataaagtc cggaactgac tctttgttaa attaccttaa cgttaccagt 2520 0 aacaccttcg taacaaaaca tcacggtata cactgggtac ggatatattc ctgtgctcct 2526 0 tccagttgct tctgcattgc catcagccgt tctctgagga tgaaataatc ccgttcagcg 2532 0 gcttctgcca gtcggggacc ggttgcatta tccacgccgg aggtgatggg ggctttacgc 2538 0 aaggagcctg gacagttggc gttgatgcgc aggcgcttac gaccagcggc aacatcagca 2544 0 cgcagagttt cattttcagc tctcgcatca gctaattccc tcgagtatct ggcatcaagt 2550 0 gcagcaacat cacgctggcg ctgctgcata tcagtaatgg ttgcatttgc cagctccagc 2556 0 tcactgactt ttttatcgcg ctgctctttg taggttatgg cgttatcgcg gtaatgattc 2562 0 agccccagac taagcgcacc acagaccacc agcagaataa cggtaaacgc ggaaagcatt 2568 0 cggtttatgc tcaccccacc agccctgccg aagtcaacgc catccaggcc atggaaagaa 2574 0 aaagagcaac cagcattagt gaaaatgaaa tgccgacaag tacacagagg ctcttcacca 2580 0 gcgttatgag tttatctgat atcattagcc accccatcaa tccgcctttg ttattttccc 2586 0 tttgcctgta tcagccagga caaaatcaat cagcatattc gcttcattta ccagcgtacg 2592 0 gatttttgat acatgcgcgg ctttaacctg tttccactca ttcagcccgg tagcaaacac 2598 0 actggcaatg tttttatccc gtttcatgtc agcacaagcc tggttgagtt cttccatcac 2604 0 gctcatttta cggggattaa cgacaaaacc cttcgtccag tactcgtaaa gaacatcgtc 2610 0 gcactcttcc tgataccgga tgaccttatc gcggatttcg ggttttactt tgttgggatt 2616 0 aatggtttgt agccagccgg caagttttcg aagtggcatg gacaccatat tgcgttggtt 2622 0 cccatcctca gcaaccataa cgatttccgt tatagttgac gcaaaacgct gtcttaactt 2628 0 agccaactgt gattgccagg ccagccccat ccccgcaacg acaggtttca tgggaacgta 2634 0 tggttcgcca ttatggttaa ctacataaag agagttgccg tgaaacggca cggccatcat 2640 0 attcatcggt tatttccttt tagtgatgaa ccttgtctca caggaatcca gcccacagaa 2646 0 aggcaccgac agccaaaccg gtatcctcaa gggtcatcct gaaaggttct gtgttgtgag 2652 0 atgcgcgtga gatgcgcaga aatgacaaag gcatcattac ggtgcctgag tgttaaacaa 2658 0 ctgctttgac tttattcact tacattttgc caatttgcag gatttcgtgt tatccgtcca 2664 0 tgtaagcaaa cctcattttt cagcaaaata ttctgcttat ctgtcgattc cccagcacgc 2670 0 cagcgcgctc tcctggtcac gacgggatac ctgaccgtaa cagttatttg agcgaatacg 2676 0 gcagtccctg ccaccgtcct taatccacca gcgaatcgct tcgcaggcac cttttcgatc 2682 0 tcctgcatta atccgtctgt aaaacgtcga cgggaaacac ttaccggggc caatgttgta 2688 0 cggacagaat gacgcaatcc ccgctttctg gggttcggtc agtggcactc tgatgttttt 2694 0 ctccacccat gccagcgcct tatcacgctc aatggcgtta acccggtcgc atttttcctt 2700 0 cgacagcttc atgccaggaa taacaggctt accatccacc cgggtggctc cacggcagat 2706 0 ggtccagata cccgcaccat cacggtatgc tgtggtgtgg ttaccttcct tttcatccag 2712 0 aaactggtcg aggatttcag gcgcagacgc ccctgcacca atcagcgcca gaacggcagc 2718 0 cgacaggccg tatctgattt ttgcgttcat ggatatttat cagggtttat cgatttcaaa 2724 0 tccctggata tgttaagtct tcaggccagc ggtggagtct tcagagaacc cgtaattatt 2730 0 cccggtagtt ttcctctgta ggttatcaac acatcctgcg cctctaaaat tacgggacgc 2736 0 ttttccggta acggaccatc cccttcacat aacccggcag caacatccat gaaaaactgc 2742 0 ttcgcctgct ttttcgcctc agcttcgtaa aactccagcg tggcaccttc agtacggtca 2748 0 agactaatcg ccacatctgg caacaacagt gacggatacc caccaatttc cggtgccaca 2754 0 gtaacagtaa tcttatccgg gtaattattt atccctttaa caaccagttc gtattttttc 2760 0 ttcatcactt tactctcccc gcgccgcctt acgccggtct tctttaatct tgaaatacag 2766 0 gttcgtcaga tatgtcagca gcccaaacag cagactcccc agcacgccta tcgccaccca 2772 0 ctgggacgga gagactttgt ccagcagctg cagtaaccag tatcccgtcc ccaccgctga 2778 0 cgtggtgtat gacacacccg ttgtgatttt ttccatctga tgtatgtctc cgtcaccgcc 2784 0 aacagaaaat gaaagtaaag gaaaacaaaa aagccgccag tgtcacccac tgacggccaa 2790 0 cgccgggagc cgtgattatg gcattcaggc tctgctaaaa atgccagata acattccggc 2796 0 ctcccccgat tcaggttata aatgacacaa tatcttgaca acatccgtca ctgtctgtca 2802 0 gaaaatgtac tgccatatag aagcaacatg tgaagtacat ctatcctttt gagccagcac 2808 0 ctctccaccg aaagtcagtg ctggctgttt ttttccttaa taaagcatct gtaactgaaa 2814 0 caatccgcat attgataata tattgacagg catcattgct gtctgtgaaa aataagtctc 2820 0 tacaaacata taaggccttt tagccagcgt cttctttttc aggtcagtcg ctggcttttt 2826 0 ttattatgct gccggtgcat ttatctccag catcagactt tctatctcaa acgccatacg 2832 0 ctgcattttt tgtaacatcc gtcagcgtca gcgcattcag tcccagtgtc agactgtctt 2838 0 ttataacctg gaatgccggg ccagccactc cattcagttt cggagtaacc gtggcactgc 2844 0 cggcggtgaa caccagctcc agcgtctgcc agtcgttacc gtaatcgccg aactccccca 2850 0 gcttcgtgtt tccggctttc ctgtgatgca tcagattcac tctgccgtca gtggtctgag 2856 0 tgaagtacga catcaggaac ggattaccgg tacccgtcat cgccacacca tcaggaacgg 2862 0 gagcgtccgt atacagataa atccccagcc cgaactgatt gttggtcagt gcgcctgaca 2868 0 ggcggaactt acaggtcagt ctgccgccct gtgtcagcag ggtaattgcg tcatccaccg 2874 0 gatgcgtcag ggaccaggtt ttattgctct gcctggtgat cttaaataca ccatctgaca 2880 0 actgaattcc gccatcctta atgctccagc cctgcgcagc agcctctccg gctgccggca 2886 0 gcagggagat tgtgcgaacg gacgtatctg cagacggacc cgatggcgtg ttgccgccgg 2892 0 gcgagggttt gatttccggt gccttaccac tgatgaaggc tgaggtgcgc ccggctgcgt 2898 0 tcagaatagc ggttgccaga cgatccggaa taatgctcct gcgcgcccat gaactgaaat 2904 0 gtgtcgggcg gtttgatgat acctggtttc cattcgttct cgatgccgca ccgtaatatc 2910 0 ctgatgccgg aatatccgga tcttctgccg gcgcgttagt ggcggtattg acgccgttac 2916 0 cgtctgtcat gaagggcaca aaataaacgc cctcactctc cctgttttta tacccgccgt 2922 0 acacggtgtc gtactgggta gcgtatgtat ttttccagta atacgtcgtg tcaccacaaa 2928 0 tccacggcac atctgcagca ctgccaccat ggcactgcgc gttaaacacg gagaggtcag 2934 0 cacgaaactg tgtcagcatg gctgtaaaca gcgcaggttg ctgtgcgtgg gtggcggcgc 2940 0 tcatgtcaaa ctctccctgc atccagcaca ccgccagcaa cacatttttc gggttcttct 2946 0 gtaatgcagc tttggtgcgc gcaatcaggt cctgatataa cggtttaccc acaccccagc 2952 0 gcgccgaatc ctggctggcc cccgtggact cgctgaatat cccctccgcg ccctgggtaa 2958 0 atgccgaacc accacgacag catggtacca gcaggatccc cgcgttattc gggatatacg 2964 0 ggagcagttt tttggcaata tgtaacccct ggccgacaca gccgtactgc cctttgctca 2970 0 ggtctgcctt cggatgattc agcgtactca tatcctgcac atcatgcagg cagtggtcgg 2976 0 ccggaataat atcgttatat ctgcaggcag ccccacccgg cgtcactgta ctgcggcgcg 2982 0 ccagctgttt aatgcgcgga tccggagcat cgtatgaatc cggcagcgga agcccttcac 2988 0 cgtaagccat ggcattggac tgcccggcca gtacgatgac gtagtaccaa tccggctcag 2994 0 ttgcaccact gaccaccaca tcaccttctg ctgtaatcgc ctgcatcagg gtataagggg 3000 0 ttatggccac cggactacca aacggctgcc agccctcttt cagtttgtgt gtcagctttt 3006 0 ccgcaaggtc tgacggcgac gccgccctga caacatcata atgtttaatc gacatcgaat 3012 0 ttctcccgtg tacaggaaca gagttaaaaa gccggaaccg gaatcaaatc acaggatgac 3018 0 catctgccag tggctggtcg taaaaaaaag ccgcgccatg cgcagccgga aataaaggga 3024 0 taacgatgat agtttgagaa aaacagaaac aacacttttg tggcaaagca tggtgccggg 3030 0 tgcctcccgg tgaattcagt atcagcacct gaatccgcga ttatcccata tacctggttg 3036 0 ctgatcgccc ctccgcacag ggggattcac catgcagaag tgtttttaat aaacagcaaa 3042 0 caaaaaaatc aagcattatg caggctgttt ctttttatca ccggccacag caataccaca 3048 0 atgccgcaga ccagcacccc atccgccagc accgacatga ttctgctggt gaaatccacc 3054 0 atcaccacca gaaacagcag gagtgcagcc acagccaggc gcagttttac cgtcacaggt 3060 0 gattctccag acgaagaccc agaacaccgg caatctcttc cagcaccttg cgctcttccg 3066 0 gctcaatttc gccgtctgcc tccgcaatgg ccaccgccac atccagcaca tcttccgctt 3072 0 cacgcgtatc gtgtttcaca tcctcaatct cacgtaacgc cgcacgacga ccagttttaa 3078 0 agttcgtatc cagctgaccg ataatggttg cgctaatcgc attaatttct gacgtaaacg 3084 0 cggacagcgc aggctgatta cgcagtacct gttcgatctt cgctttctcg gatgcctcac 3090 0 attcaccatc tgcacaggcc accaggtatg cggcgttaat caccacctgt gccagatcgc 3096 0 gtttttcaaa ctttttaatt tccgttgccg ctctgcgggt tttctttttg aagattccaa 3102 0 acatcgtgac gttcctttgg gtgggtgagc caacgcccgg gagcgatctg cccacagaga 3108 0 aagtcacact gaccactccg taagctcacc cccgaaaggc tctgtggttg gtatgcgccg 3114 0 ggcgtggcgc agatacaaaa aaggcccgcc gaagcgagcc tggaaaataa gtgtggcgcg 3120 0 ttgtagtgga gtcgaaccac tgaccgattg cttagaaggc aattgctctg tccggctgag 3126 0 ctaacaacgc agaataccga taatggaccg ccatcgggga cccggccccg caccaacaac 3132 0 cctgttatgg tgtcgtctgc tcttcctgat aagctaatgg cggtttgtga tggtggccct 3138 0 tgctggattt gaaccagcga cctggcgatt atgagtcgct cgctctcacc actgagctaa 3144 0 agggccgagc caaaaaataa taatcagatg aaaatcaata atcaagccct tgcctggata 3150 0 catatctgtc tggcgggaag ccataatagc ggtgaaatac agaaataaag taggaccggc 3156 0 ttgaataacc acatttttct gctacagcct gtccatatcc ataccgggaa cataacatat 3162 0 ttacagcaac acgcatccgc tcttccagca acaagcgact gaacatgccc ccttcatttt 3168 0 tcagttttgt ctttaacaaa ctctcactca tatgcaactg tagagcaatc gcaccaagcg 3174 0 tccagcttgc tgatatatct gtctgaatta tcgccctgac tttggcactt atgctggata 3180 0 aacatccact taaaaacaat gacatccgtt catctgtttc aaacagagac aggcaggcca 3186 0 tcataagaaa catatccgtg acctctccgg aaaatccctg gctggtaatt aaagccgcag 3192 0 ccaacgcagg attgttgggt tccagcaaca ggtaaagcgg aatgtcagtc agacgagtcc 3198 0 tcgtcagctt atgctgactt tccagatatt gacttacgac ggattcgctt atatcgacaa 3204 0 ttttaacttt gccataatgc ataaggaaaa gctccctgat gcatttggtg gccagaacga 3210 0 ctgagcctgg cttaagtgac aacgtatcct tttcaagaaa aatattaatt ggggagcaaa 3216 0 ccatgataac tgaacagaca acagccatta taattttact ttcattagca attggttagc 3222 0 tcaattatag ccccaaaagg taaattatca tcaacacata agcaaaggac tgacaggtgc 3228 0 cgcccccccc accagccgcc catttaccac aaataaaaag ccttcaggac tgaatgcgtc 3234 0 tgtaacaacc gcactgatag tctgccagac ccgccataac cagctgggtc agtattaact 3240 0 ggcagcgttc gcgtgaaagg taagtattct gcgcaatctc cccgactgtc gccggttcgg 3246 0 taacgcttaa ttcattaaac accactctgg cggtttctgt catatcctgc tgttttagca 3252 0 tgtctttttc ccttttccgg ttaacgtgac ataccaataa ctcttgtcga aaaagccagc 3258 0 aagttgaaag accggtatta gcaaccacca gcgcgtttaa cgccccgtgc cgtttttcag 3264 0 tcataaaaaa acccgcaaaa agcgggctct ttcaaatgtc catgtctgct attcgcctcg 3270 0 cggtacagct ttgcgaagct taccggaatt gaagcagttt ttacgtcaaa aagcaataac 3276 0 ttttttctct ataccaaaag ccataaccat tggtttgtac aaaataaatt ctgccacctt 3282 0 tagccaatgc tcaatgcgtc tttcacaggt tcttaaactc cattccggat gtgcatcatt 3288 0 cagcaattca gccattttgc gcttagtcat cccccgcccc acataacgct gactcagaac 3294 0 attgagcagc ccgggataac ctgccagtac ttcaccaata accctatcga ttattaacgc 3300 0 ctctgaatcg gtacaatgtg ccagccagct tttttgattg ccgttgatca tatcccgcaa 3306 0 aaaagcctca agttcaggtt tgtccagacc cgcttttttc atcctccgga gcgcctcgtt 3312 0 aattgccgtt tttgtcagct ttttagaggt cagtaattgg ttgaacatat ttcccgtctt 3318 0 accgtcgcca atatacgacc aacgccccca catacgcagt ttcccctgga tccagacact 3324 0 ttccagcgtt ttcaggcgta aatgctcacc gcttttgcct gtaatttccg ggtatatcat 3330 0 atttatgctc actcactttc aattttgtaa atcttcacgc ccagccgccc accagaaacg 3336 0 agctagccgc gcacaatatt gatttcatca aactgctcgt cgtctatgag aagtccggca 3342 0 tgcgtcagcg catccagtgg tgctttcagg atattgtcca ggtcacgacg gcgcttatcc 3348 0 ggtggctctg caataatctt tatcgccagc cttccggaca ggtttaattt cagccgctgc 3354 0 tggcgaacaa taagtgccac atcccggcga taacgctcac cggcttttga tacaaaatat 3360 0 gtgctgccac gacgtcgcca gtaggtgttc accgtcggcg ggtaaggcaa aacaaactct 3366 0 atacgcatca gtaacctctt ttacccgagc acgccggttg caaaggcgtg atcaagaaaa 3372 0 cgaaaaatta aatcaacctg ggaaccatgc ttttcttcga acgccagcgg atccgcatga 3378 0 agctcgttgt gatgctcccg acacagcggt agcgtgaaaa tatcgtggga ttttgttccc 3384 0 attccgccct gaccatgacc aatcagatga tgaggatcgt ccgctggctt accacaacac 3390 0 gcacacggct gtgtctttac ccagcgtgtg tatttctcat ttacccagcg gcgacgttta 3396 0 ggtcgtttca tgaaggattc cggagactcc ggatcaacgg caatgctgac caccgtcttt 3402 0 tcctgtggtg ggttctgttg ctggtgggtg tgaggcggta gcgcaatatt ttttgtgcgc 3408 0 tgcttcagta tgctggtggc ggtctgttct cccggtatga tgtcgctttc acggtatacg 3414 0 gagcggattt tttccgccgg taatcccaga gagcgacgcg atactgcctc aggtaatgcg 3420 0 tccaccacct gattgcagac tgcccaccag gataattcag ccagcgataa ttcccgctcc 3426 0 tgcgtgccat tcattacatg gcgtatgacg tcaatcatcc aggctgtcag attttgttga 3432 0 gtaagttgct caagtgattc ggaggtctgg tcgcgcagct ggttgtcgca gtgccagcac 3438 0 aacaccattg cgccagcacc gtaactgtga ataacggttt cgctgtgatg ataatcgccg 3444 0 tgtggccact ggcaggattt cacgtgacgt aataaccagt cagacagtgc accagcgccg 3450 0 ccagctgcac gaatcacccg ctcatcgctg aaaaatggca gcagtgattt atcttccgcc 3456 0 agcggctggc gaacagcagg aaccgctcca gatggcagcg cccgcatgtt tttcggttcc 3462 0 ggctccacca gcaccctgcc gcgatgaaaa actggcaatg attcacgacc gggcttaagg 3468 0 accaccagcc cgagttccgg aaccagaaca ggtcgaagta atacccgcac attacctcca 3474 0 gacgcgctga cggtagcagg catgtgtccg tggcagatgt gcacgaacag gaagatatac 3480 0 agaaacggtc caggtcagac gatcagcgtt cagactccgc tccacacgga caccgcgacg 3486 0 cagatacgcc tcttgaagca tatctgcctc atcgatcgta cagaacagat agtgaaacca 3492 0 gccatactga ggcgcacgaa aacgcctccc ctgcttaatt tccgggtcgg cttcagaatt 3498 0 gtgggatttt atgtgttgtg tcatcggatt ctccggtgac agcaggtgtc agttgttcag 3504 0 gctgactgcg cgaattgtaa ggcaatacgc cggaatgtac aaacagaaaa cccgtcagta 3510 0 agacgggctt aacaagcagg ggcggttact ttaataattt cagtgccttt acatcaactt 3516 0 caacactgct caggtcttta tcaatttcac cctcaattct tactttgtct ttcggagaaa 3522 0 cattctgccc ggcccatacg ctgtcatcaa tatccgtgac aattgtcccg ctattgtcac 3528 0 gaaactcata acgttcatca cccacttttt taacgatgct cccttcaagg ataacccatg 3534 0 catcatcctt cagttctttt gcctgcgcta ctgttgaacg ctctgcttct ggcccctgga 3540 0 aaccaccctg ctgtgcaaaa gcgccaaaag acacaccgga aataagtgct gcaatcaata 3546 0 cctttttcat tcatagtcct ctttcagaga tgaacattca aacagcattt tcagtatggt 3552 0 aaagcgcggg tgcgttgagg atgcctgaca catcagaggt ggcgggagat tactcccccg 3558 0 cctggtctct tacttctcag attcgtagtc tacgaagaca gcgacctccg tctgaccggt 3564 0 tcggattcgc acctcgcaga ggtctttcct cgttaccagt gccgtcacta tgacggttaa 3570 0 acagatgacg atcagggcga ttaacatcgc cttttgctgc ttcatagcct gcttctcctt 3576 0 gcctttcggc acgtaagagg ctaacctaca tgtgttcagc atggattgag cctcagatta 3582 0 atgttaagcg tcttgcagga cgcgtaatgt taactggggc ttttctctat ctgccgttgg 3588 0 tgttcatgcc cgaggcagat agcctcaagc acccgcagca attctactta actatccttt 3594 0 tcccgcaaac cgtttttatc cccagcggca aatcgaatac accaccagcg ccaccgccat 3600 0 cgcaattcct accgttgtga atgcttcagg ccaggtcatt gattcacctc ctgcggcggt 3606 0 tctggtagcg acatccagtg ggttgcttgc ctaagatcat tacccggact aactgctata 3612 0 cctccgcgcc ggaacgtgcc tccgagatag cgtgcggaat atattaatgg cccagcctcg 3618 0 ctatcgatat tcatcgaaat aagcacgttc tggctctttt caggcattcg ctcagtacag 3624 0 cttatccagc catccagagt tatcggagat ctggttgacg tttccgagat ttcccgaaaa 3630 0 ttgttggttg acgaattctt attttcccga aagtttccgg cctgaagcat ggcgacgcgg 3636 0 caggcgttcc agccatcagc atatgtttta gttacaccgt cgagatggca ggtaagcaaa 3642 0 tccatttcat caggcactac cattgctatc ggctctgctt ccagtgatgc cagcgcgata 3648 0 cgaaacacat tagccagcag gctgtctgaa gacttgttat cgtgcgccga gtcgctcagg 3654 0 aagcctgtga tgtatgattt aatctccgcg cgttctctgg taatagtgct catatcagtt 3660 0 ttccttatac ggattaattt tattgtgcag tgcgctgaat gattcccatg tcacatcggt 3666 0 atatagctca ataactggtt caaatgtcct tccaattatc cagaccagta atagcgggga 3672 0 tatcggtatc atcaacacta taaacagaat gaaaaacaga aactctgttg ttctgctctt 3678 0 tcgtgggtaa tttttttcta aataatgttt catttcttac cgccctttcg ggcggcctcc 3684 0 tgatgttctg agggtgcagg aatccctccg gttaaggatt taataaaaat cgtttctgat 3690 0 ttaaatcttc agtatttagt tgttagttgg tttatcgcct ttatgcttca gccttatttc 3696 0 gcaaccagac acaaaccggg ccatcttccg tatcatgaat ggaaccaata aaccagccat 3702 0 cgccctctgg tcgttccggt tcccatgcag aaatatcagc atcacacgca tcaaggtcag 3708 0 cacatccttc atctctgaag cagaggacgt attgaagatt attttcctcc atccaggcgt 3714 0 taaactcttc cgttgaaata tattcccgac catcacagaa tttttcatat tcaggatgtg 3720 0 tccagtagcc atatccgtca cgaactaccg gcatttcttt aatttcactc actgttaacc 3726 0 tcctgcaacg ctacacgata cgccttcttt atccacgcct tactgccata taatttcgtc 3732 0 ttcataataa acacacctgc acgactcgcc gatatccccg gacaggttaa cagcacagca 3738 0 tccaccacac ggttatgctt ccgaaactcc attacagtac tgctgataac cacctgcccc 3744 0 accgggccgt aatcctgata caggattttc acgcagacac cctcctgtcg aaataaacgt 3750 0 agttattcac tatgcgcagc ggcatgccta attttctggc aatttccctt ctttgcatgc 3756 0 ctctctgatg cagttgccgc gccagctcaa tatcacgctg agaatatttt gccgacgggt 3762 0 gaaaatcacc acgtaacatc atgctgatgc ccagctcccg tgccttcgtt ctcactgccg 3768 0 cttcagttcg tccgataagt gcgccaacgc tttttacctt catcgttccc gcacactgcc 3774 0 ggagtatcat gatttccgcc cggcaccacg tcttccaccc actcaccgct gctgttctct 3780 0 ggtggcggta atatcccgga gaatatcccg gcacttgttc agctcccgca gcgcggcgca 3786 0 gactcgctcc cacttctgaa cctgaccttt tgcccggcgc agctcgcggt tagccacatg 3792 0 cagcgatggt aaaatcagac catccggatg ctttctggtg aacgacggct gtgactgcac 3798 0 tgtgaccgcc acactttccg tttttatttc ttcctgtgtt tccgcttccc cgactggtaa 3804 0 cgcaacacct gctggctgag gaaaggcttt accatccgtt tccgttatgg atgcggcttt 3810 0 cggctctgcc ggtaaatcag cgcccggtat gcagtaccga aatttaccgc cctgattcac 3816 0 gcgaatcaga cgccctttgc tgattgccat ggccagtgat gaattcgccc ggcgggaggt 3822 0 aatcccgaac atcagtgcca gctcatccgc cgtttgtggg ccatgatgtt caatcgcctc 3828 0 agtcagcatt tgcgctgtca ctttcggtac cggtgacact ggttcacttt caccagtctg 3834 0 agtcagccac cacatcgacc ccttgttatc cgcttcacca cggcgcttca gtttccacag 3840 0 ttcgttgaca gcatcttcgc ggctgattcc aaggcgcgat gccactacct gtgaagaggc 3846 0 ttttttcagt gctttcagtg cgtcaaatac ggtttccatt aatatttcct ccgacaaaat 3852 0 cgtttctcag attcaaataa aaccagctgc cttccggcgt tcgtattcct gtttcagccg 3858 0 ttcaattggc gttggccctt gcgggtgttt cgccccttcc agttgtcgtc gcactggcgg 3864 0 aacactcatc ccgttaccaa catgctttgc ccatttcgtc agttgccgtt ccgcaagtcg 3870 0 ttttaactca ccttgcgtca tctggcgctc aatccctctg gtacgcattt cgaggcagat 3876 0 gtggtacagc acaggctgtg gccacgggta tttatcactc ccgtcgtatc gccaggattc 3882 0 attgcgccag cgccggtact cttccatcac ggcatccacc gtaagaccaa atggatttgc 3888 0 cccactctcc gaaatcagcg caacaaactc agccaggtcc gggggccacg tttcacccgc 3894 0 ccggcagcgg tccatgcact gacggcacac cagacggatt tgctgttcag tcatcgcacc 3900 0 aatctgggca atccagagct tcgaaggtgc ggccccgttc ttctgagtcc agcggttcga 3906 0 atacacctcc cccatgagct cccacagctt ccaggccgtt tccgttgctg ataaatccgt 3912 0 tgtcacgttc ccactgttcg cgtgcagccc ggatttcctg aactgcccgt gatgccgtgc 3918 0 cacctgatgc tgcatggctt ccccccttgc tgactggttt tacctgtgcc ctgacgtgct 3924 0 gcacgtggcg ggcaaatttc tgctcccact gaacctgcgt gaaaaccttc ccctccgcca 3930 0 tccagtaatc ccggaatgcg gcaagctcag caggtgtaaa ttccggctca ggcagagcca 3936 0 taccccacac tgctgcccgt tgtcgaaaat ccggcgacgg ctgccagaca gtagtcatcg 3942 0 aaaatttccc gatcggttcg ctcaggccgt ccaggtattc aggttcggct gtctgcaacg 3948 0 gcgcaccatt cgactcactg gtcggaatac tctcgcgcgc gttatgtgtg gggtttaatt 3954 0 ctgtatctgt atctttatct gtatctttat ctgtcgtgac ttgtcgtgac agatgcgtga 3960 0 cacgtcgtga ctcatcgtga caatcagcat tatgtttccg cagcttttcc cgctcccgct 3966 0 gcgctctctt gcgctctgcc ggggattttg ccgtttgcga aacgttacca ttgtcctctt 3972 0 tcagcacctg acgtttttcc catccggaaa taaggtcacc atccagaacc cgcccctgca 3978 0 ttgcatgcaa aattgaatca attacgtctt ccgtcacatc aagcgcactt gctaaatctt 3984 0 ccgtcgtgac atcaatgtga ccacgtagtg acacgccgtg acatgtcgtg acatttcgtg 3990 0 acgcgctcac cagaagatgg atatacactg ccatcactgt tgcgattggc tgtcctgata 3996 0 ccctggcaat cgttcgccac ttggggtcat ttggcatgtc atgccacaat ctgagccagg 4002 0 cattagccat actcacctct tctgataccg aactttaccc tcgaacatcc ggaagaaatc 4008 0 cggcatgaat attgttggtc aatgcacgac aacagcatta ccaggctgac ccccactgtt 4014 0 agtcagggtg ccccaggcga tcgccgctgc gacaaaatca tccacatctt tcaccagccg 4020 0 atccctccgt tcgacgatct cacggtaata ttcagagctg tgactgcgca tacgggccac 4026 0 cagcagaggc ggcattgcct tttcgatcgc cggtaacaga gcctgcattt tttcaactgc 4032 0 atcaggggtg tctttctcta tccagcggaa aattttctgg gtattgcgag ccagggcttc 4038 0 cggatggctg tcgtcgtaca gttcaggaaa cgtcataccc aactcaaaat aagcctgggt 4044 0 tattccagct gccggaactt tttcgccatc aggacgcgcc caggcattca tcgccatgcg 4050 0 gatgtgttca tgcttgattt tcatgaatcc ccccttggtt agaaggcgga ttatgatcag 4056 0 aatcgggaat gacaaccgtc ggtatgtgta actcatattt gagcgccccg gcagtgactg 4062 0 cctgaattag caacgcccat ttccacggaa cgtcttcccc ccacatgctg actgtggttt 4068 0 ttgacgttcc tagagcggcg gctgttttaa caactccgcc aaaatagcct aatacttctg 4074 0 attttttcat gagtcgctcc ataaaactga acgccaaaag tttaataatc aaaaccaaag 4080 0 aaagtcaaga aacaaaacca tctgtgtttt aaaatcaaaa catgaacaag caaacaatat 4086 0 ctgaacgcat aacccaacgt atgcatgcgc taaacttgaa aggcaaagac cttgtcaatg 4092 0 ccactggcgc atcaaaaggc tccgtaagtc aatggatgaa cggtggagga gcgccgtcct 4098 0 cgcgttacat aagttcactg gcaaagatat tgaaagtaaa cgaaaattgg cttcttaatg 4104 0 gaggagagtt aaatacaggt gattcgcttg atctatcttt accgccgata aaaacggttc 4110 0 cgctactatc acttcagcag gcagcaagct ggagtgatta tatgaaaaat tcctcaataa 4116 0 cctcttgtgt gcagcttgtc ggagaaatcc cggccaatac ctttgctgtt gttctagaga 4122 0 gtgacagtat gtcgacatct ggtggtggag tttccatccc aaatggttca acagtttttg 4128 0 ttgatcccga tcgaatcgta caaccaggaa atattgtcct tgccttaccc aaagggacca 4134 0 caacgcctgt cattcgcaaa ctggagatag aagggccgga tattctttta gtccccacga 4140 0 atcctcgcta cccttcaatt atgctggatg atctatcttg catattggga gtatgcttta 4146 0 aaattcaaca agatatttaa ccaacctcat ctatttgatt aactgtatgc catcgtagtg 4152 0 atggcgtaac agctgcctgc ttaaaatgtt ttgataaaaa aacattgacc ttaaatgttc 4158 0 gtttttctaa acttcattca ttccctcacc ccgccccaca gaatgcaggg caatacttcg 4164 0 agttaccagg cagtggtcag gggttaagta gccagcccga ggcgtaagaa catgacggca 4170 0 gggttcaact ttaataacta tgcagcaggt ttttgttccg ctaccccggc gttaagggga 4176 0 aatgaggtca acatggatac gctcaatctt ggcaacaacg aatctctggt atgtggcgtg 4182 0 ttccccaacc aggacggtac gttcaccgcg atgacgtata ccaaaagcaa aacgtttaaa 4188 0 actgaagctg gcgcgcgtcg ctggttagcc agaaacactg actgatgagg ttgacgatgg 4194 0 aatttaaaga tttacctcct tcaatccagg agattgcagc acacacactt cgtcatcgtc 4200 0 tgaacgaact tgaattggaa tcggtaacga aaaaagacac tgataatatg gctcgtaatg 4206 0 tgcgcgatgc gtttaccgga ttgtatttct gtgcgtctat aaataaacac gactcagaga 4212 0 gtgtggcaaa taaaattgca gaaacgacag cgcaaaacat caatacgaaa ccaacggaag 4218 0 aagaaattga tcagtttgct catgatgctg gtttaaaaaa caagaaagaa aaatcgccat 4224 0 atgcggggaa catgtttgtt tatgacaatc tcatcagaat tcgtggcgaa attccggcgg 4230 0 aatacctggc aagagtccat caggcattgc ttaaaaattt ggaaacagaa ttatttgatg 4236 0 gcaacactaa cggtttcttc atggtatcag gccttgagaa agactgggat gcagaaaaac 4242 0 gctggaatgt tgctacatgg ttattcagta acagagccgc tgcactggaa gcttcggcat 4248 0 gtatttgcgg cctgttctta acagaccaca aatataatct ggatgtgtac agttatattt 4254 0 acgctgaaca cggtccactc tggattgact ggtaattata aggaaacacc agcagggccg 4260 0 cggcgaccaa cagaacgatt aaaatcaata atgccattat aaaggacatt atttaattta 4266 0 tcgtcgaatg ctgattctgt gagcctcaac tctgaatgag tttttaataa ccctgattgc 4272 0 ctgagttgat ttaccaggca ttcaatctgt ttttcaataa gcggatttct ttttttgttt 4278 0 ggcattttat cctccattga ggttctgggt taaaaatgga gaccaacacg ctgtcacgtg 4284 0 tggtcgtgcg ccggacacgg ataagaatcc ggtactgaca gtttactgaa aggatatttc 4290 0 cctgaaaagt cagtgcataa cgcgaaagcg tacggcgaag ctctttccct tagaaggctt 4296 0 gtcgttagat ttcttcgaac gtgcgcttcc ggttgtggca ctccgcgaaa tggcgcggcg 4302 0 gtaagtatgg cggggttatt ccttccccat tgaggacacc gggttgtcag gttgaccata 4308 0 cgcttaagtg acaaccccgc tgcaacgccc tctgttatca attttctggt gacgtttggc 4314 0 ggtatcagtt ttactccgtg gctgctctgc cgcccttttt aaagtgaatt ttgtgatgcg 4320 0 gtgaatgcgg ctaagcgcac gcggaacagt taaaaccaaa aacagtgtta tgggtggatt 4326 0 ctctgtatcc ggcgttaatt gttaactggt taacgtcacc tggaggcacc aggcactgca 4332 0 tcacaaaatt cattgttgag gacgcgataa tggaaacgtt attaccaaac gttaatacgt 4338 0 ctgaaggttg ttttgatatt ggtgttctgc tcagtaaccg ggagtttact gaagatgcca 4344 0 ttaacatgag gaaatatgag ccttatctgc tcaatgataa ttccatactt tcccgaattg 4350 0 ctcttcttga acttggtatt ttcggagaac gtcaatgact tcagcatttg cactgatgat 4356 0 gacggttttt cttataacgg gtgaatcaca gaatgtgatt accggaattt atgccagtaa 4362 0 agaatcctgc ctccaggcaa gagacgagca aaaaatttct ggtgaatgcc tcccggtaaa 4368 0 aaaagtatcg ctgtacctga ataacgaaac accggctgga taaccctcca gccatattaa 4374 0 caccatacca acggattaaa aatgccagca atggcaggga tttgttcacc cttaaatctg 4380 0 taatgaggtt tatcaatgag cactgataaa gaagaatttg cgctatattg cgaagcaaaa 4386 0 aatgacaaag tcagaaaacg tctgggaatt aaaggtggtt tttactggac tacagcaaaa 4392 0 aaattatctg ttgccatctc ccgctgcatt accgcaatgg atgacaacga ttatgatgaa 4398 0 gacgacttta aaaaacccgt tcgcgtccat ttacccgttg tgaatgacct tccacctgaa 4404 0 ggcgtgtttg ataccgaatt ctgcaaccga tacgaaaaag gcggggaaga tggcattaca 4410 0 atggtattta tcgcgccctc tccctccgtg caggagaaac cagccagtac tgacaatacc 4416 0 aacgtcaacg gcgaagacat gacggagatt gaggagaata tgctcctgcc ggtttctggt 4422 0 caggagctgc ccattcgctg gcttgcgcaa cacggcagcg aaaaaccagt aacgcacgtt 4428 0 gcacgggaag aacttcaggc attacatata gcacgggcgg aagaactgcc ggctgttact 4434 0 gccttggcca tttctcacaa aacaaagctg ctcgacccgc tggagattcg cgaccttcac 4440 0 aaactggtac gcgacactga caaagttttc cctaatcccg gtaattcaga cctgggactg 4446 0 ataactgctt ttttcgaggc atacctggac gctgactaca ctgatcgggg tctgctgaca 4452 0 aaagagtgga tgaaaggaaa tcgtgtttcg cgtatcaccc gtacggcttc cggtgcaaat 4458 0 gccggtggcg ggaacaaaac cgatcgcaat ccgaatttag tacacacctt cgatacgctg 4464 0 gatgtggaga ttgcagcagc cacacttccg atggatttta atatttatga aattccgggc 4470 0 agcgtttatc gtcgcgcaaa agaaatcgtc ctgaaaagag aaagtccgtt caaagaatgg 4476 0 tccgcagcac ttcgcgcaac cccgggtatt ctggactatt cccgcgccgc tatttttgca 4482 0 cttatccgga gcgctcaccc tgagttttat cactacccgg gacgccttca ggggtatatc 4488 0 aacgcctact taacggagac tgatcacgag aaccccagca aggaaactct cactgctgca 4494 0 cgacatacac cggaaaaaga tatcctggaa gaagttaacc gcgaactgtc tgctaagcag 4500 0 gaaacagaag aagaaaatga tgaagaaaaa ccgcaaccat cttgcgcaat ggcagaatga 4506 0 taatcagaag aaatctggca aaagaccgtt ttacagtacc aaaaacacag gcgggaacca 4512 0 atcgtgtgat tcaccttatt aagcccgcaa tcgacgctct ccggagtcag atggcactaa 4518 0 cgagactgag caaagagcat atcatcgatg ttcacctcag agaattcggc agaacagaga 4524 0 aacaaaaatg tacctttgtt tttcaacctg aagtgtcagc gaaagtaaaa aattatggcg 4530 0 accattttac cgttgactca ataaggcaga tgtgggacgc agcggtaaag cgtgccggaa 4536 0 tccgccatcg caaatcgtat cagtcgagac acacttatgc ctgctggtcg ttaacagcag 4542 0 gagctaaccc ggcattcatt gcaaaccaga tgggccatgc agatgcgcaa atggtgtttc 4548 0 aggtgtacgg gaaatggatg tcagaaaata ataatgcgca ggtaacgctg ttaaatacac 4554 0 agttaagcga gtttgcccca accatgcccc ataacgaagc gatgaaaagt taatttttta 4560 0 tttatcaatt agttagattg aatgactctt gaaatccata attcatagat gttttttact 4566 0 attctgtggg tttttgggtg ttttctaagt tttttcagat ggttgtattt tttctaaaaa 4572 0 tccctaatct cgattttgct gtttatttga ggccttttta tgtcccatat atgccccaca 4578 0 gataccccgc agccaaaatc aacaaaatgc caaaaggttc tgttcctgcc ctgcaacaag 4584 0 aaatgctgcg acgtgtcagt aaacgttatg acgatgtaga agtgatcatc aaatccacca 4590 0 gcaacgatgg ccttgaaccg ccccggtttt cctggagagt gttttatctg tgaactcagg 4596 0 ctgccagatc atcgtttccg atggaagcat aataagcttt ttctgcttct gccggaggag 4602 0 tatggcccag ccttcccagc aatcgtcgat tgttatacca gtccacccac gttagtgtgg 4608 0 ccagttccac ttctgcacgg tttttccagc tcttacggtg tattacctcc gctttgtaaa 4614 0 gaccattgat gctctcagcc atcgcgttgt catacgagtc gcctgtactc cctgttgatg 4620 0 ccagtaatcc ggcttctttt agtcgctccg tataggccag tgacacatac tgagagcctt 4626 0 tatcgctgtg atggatggtg ccagacggac gacgggccca caacgcctgc tccagcgcat 4632 0 ccagcacgaa tgtcgtttcc atagacgatg agacccgcca ccccacgatg tatccggcaa 4638 0 acacatcaat gataaacgcc acatagacga agccctgcca tgtgctgacg taagtaaaat 4644 0 cagccaccca cagctggtca ggtcgttctg ccacgaactg acggtttacg cggtcgcctg 4650 0 cggcaacggc tttccggctg atggtcgtac ggaccttttt accccggaga acaccggcaa 4656 0 gtcccataac cgccatgaga cgtgccactg tacatctggc caccctgatt ccttcccgta 4662 0 acaactgacg ccagacttta cgcacaccgt acacctgatg attttcatcg tatacgcgct 4668 0 gtatctctct cttcagccag tcgtcgtgct gcgcacgggc actgcgttta tccggatgat 4674 0 gtcgctgttg ctgacaatgg taatacgttg acggggcaat atgcagttcg ctgcataccg 4680 0 gtccgacccc gtactgctca cgcagcttat ccagcagtgg catcattttt tccagaggcg 4686 0 gtcgaactcc gccttcgcaa aataagcgga agcctggcga aggatatcgt tactgcggcg 4692 0 cagttcacga ttttcacgtt ccagctcttt cagacgctga cgttcagcgc tggtgagccc 4698 0 accatcaccg cccccggtat cccgctcatg ctggcgaacc cagacacgca gagtctccgg 4704 0 cgtacagcca atctttgggg caatggaaca aattgccgcc cactgtgagt catattcatc 4710 0 ctgactttcc agaaccatac gaatcgcccg ctgacggact tcgggggaaa aacgagtatt 4716 0 tttagtcatc ctgtttacct ctttctcagg gagtttagtc tccaggattt ccggggcggt 4722 0 tcacctttca gttactcgca ccgccgataa agattctgca aaaacttttg ttcaggagac 4728 0 gctgaaagat acctgggagt ctgctgacga gtggtttgtt cgctaattaa cgagtaaaat 4734 0 cgaccctgta cacgattctg tgtaaatgcc ttttctcaga agtgaccgtc caggcggtca 4740 0 ccgaactcga taataaagcg gctcattgcc atacgccagt cccgcagtgg catcgtccat 4746 0 ttctgtgaag ccgcctggat tgccagccac acgacctttt tcactgagtc atccgtcggg 4752 0 aacaccttgc gttttttgat ggcatgccgg attacgctgt tcagcgactc gatggcgttg 4758 0 gttgtgtaga tgactttgcg gatatctgcc gggtaagcga agaacatcgc caggttggtc 4764 0 cagtttgcct gccagctccg gcttatctgc gggtagcgac tgtcccaggc gctggcgaac 4770 0 gcttccagcg cctgctggcc tgcttcttct gtgggggcct ggtagatggc tttcaggtcg 4776 0 cgggtgacgg ctttgtagtc cttccaggaa acgaaccgca ggctgttgcg caccatatgc 4782 0 acgatgcaca gctggatgcg ggcttccgga tacaccgtgt tgatagcgtc cgggaagcct 4788 0 ttcagcccgt cgacacaggc tatgagaata tcgttcaggc cgcggttttt tagttcagtc 4794 0 agcacattga gccagaactt cgctccctcg ttttcggcca gccacatacc cagtaactct 4800 0 ttctggcctt cgatattgat acccagtgcg aggaatacgg atttattgat tacgcgactg 4806 0 tcctgccgaa ccttcaggac aatacagtca agataaacaa tgggatagac cgcatccagt 4812 0 ggccggtttt gccattcgac tacctgctcc ataacggcat cggtgacctt cgataccagc 4818 0 gccggtgaga catcaggtaa gcgtacagcc tgaaccgtct ggtcagaatc tgacgaatta 4824 0 gacaaagtgg tgtccaccaa ataagtagtg ggaaccaaag tatcagatat gcagaaaaat 4830 0 gtgactcccg gcaggcgaaa aggctgccct aattatcctc ccgaatttaa acagcagctc 4836 0 gttgctgcct cctgtgaacc cgggatatcc atctcaaaac ttgctcttga aaatggcatt 4842 0 aacgcaaatc tgttgttcaa atggcgacaa caatggcgcg agggaaagct gctattacct 4848 0 tcttcagaga gcccccagct acttcctgtg actctcgatg cagctgccga acagccagaa 4854 0 tcgctcgcag aggacccgga aaccctcagt atcagctgtg aggtaacgtt ccggcacggg 4860 0 acgctccgct tcaatggcaa tgtcagcgaa aagctcctga ctctgctgat acaggaactg 4866 0 aagcgatgat cccgttacct tccgggacca aaatttggct ggttgccggt atcaccgata 4872 0 tgagaaatgg cttcaacggc ctggctgcga aagtacaaac ggcgctgaaa gacgatccca 4878 0 tgtccggcca tgttttcatt ttccggggcc gcagcggcag tcaggttaaa ctgctgtggt 4884 0 ccaccggtga cggactgtgc ctcctgacca aacggctgga gcgtgggcgc ttcgcctggc 4890 0 cgtcagcccg tgatggcaaa gtgttcctta cgcaggcgca gctggcgatg ctgctggaag 4896 0 gtatcgactg gcgacagcct aagcggctgc tgacctccct gaccatgctg taaatctctt 4902 0 tatcctggtt gtcacagaat aagcccggta aaatacgggc ttatgaacga catctcttct 4908 0 gacgacatct tcctgctgaa acagcgcctg gccgaacagg aagcgctgat ccacgccctg 4914 0 caggaaaagc tgagcaaccg ggagcgcgaa atagaccatc tgcaggcgca gctggataaa 4920 0 ctccgccgga tgaacttcgg cagtcgttcc gaaaaagtct cccgccgtat cgcacaaatg 4926 0 gaagccgatc tgaaccggct tcagaaagag agcgatacgc tgactggtag ggtgtatgac 4932 0 ccggcagtac agcgtccgtt gcgtcagacc cgcacccgta agccgttccc tgaatcacta 4938 0 ccccgtgacg aaaagcgact gttgcctgcg gcgccgtgct gcccgaactg cggcggttca 4944 0 ctgagctatc tgggcgagga taccgccgaa cagctggagt tgatgcgtag cgccttccgg 4950 0 gttatccgga cggtacggga aaaacatgcc tgtactcagt gcgatgccat cgtgcaggca 4956 0 cctgcacctt cgcggcccat cgagcggggt atcgccggac cggggctgct ggcccgcgtg 4962 0 ctgacctcga agtatgcaga gcacaccccg ctgtatcgcc agtcagaaat atacggccgg 4968 0 caaggtgtgg agctgaggcg ttcactgctg tcgggctggg tggatgcatg ctgccggctg 4974 0 ctgtctccgc tggaagaggc gcttcatggc tatgtcatga ctgacggcaa actccatgcc 4980 0 gatgataccc cggtccaggt actgctgccg ggtaataaga agacgaagac cgggcggttg 4986 0 tgggcgtatg ttcgtgatga ccgcaatgca gggtcagcgt tggcacctgc agtgtggttc 4992 0 gcttacagcc cggacagaaa aggcatccat ccgcagactc atcttgcctg cttcagcggt 4998 0 gtgctgcaag cggatgcgta cgccgggttc aacgagctgt atcgcaatgg tgggataacg 5004 0 gaagctgcct gctgggctca tgcccgccga aagatccacg atgtgcacgt ccgcatcccg 5010 0 tcagcactga cggaagaagc cctggagcag atcggtcagt tgtacgccat agaggcggat 5016 0 ataaggggaa tgccggcaga gcagcggctt gctgaacgtc agcgaaaaac gaaaccgttg 5022 0 ttgaaatccc tggaaagctg gttgcgtgaa aagatgaaga ccctgtcgcg acactcagag 5028 0 ttggcgaagg cgttcgcgta cgcacttaac cagtggccgg cactgacgta ctatgcgaac 5034 0 gatggctggg tggaaatcga caacaacatc gctgaaaatg ccctgcgggc ggtcagtctg 5040 0 ggtcgtaaaa acttcctgtt cttcggctct gatcatggtg gtgagcgggg agcgctactg 5046 0 tacagcctga tcgggacgtg caaactgaat gacgtggatc cagaaagcta ccttcgccat 5052 0 gtgcttggcg tcatagcaga ctggccggtc aaccgggtca gcgaactgct tccgtggcgc 5058 0 atagcactgc cagctgaata acacatcccc gtcaatacgg ccctcgctgt acgcttacga 5064 0 catcagcgtc atacagctct ttaaacgcag ccgctatttc gcgggttgtc aggcctttgg 5070 0 cgtacaacga caggatctgg ttatccatcc cggtgatccg ggtctggttt ttcttcacaa 5076 0 gttgcggttc aaaagagcca tcacgatcgc gcggagtgcg tagttccagg tggccatcac 5082 0 cggtgataac ggtctttgtg gaatagccat tgcgggagtt ggcacccggt ttaggctggt 5088 0 ttttatcgta gcccagatgg tgggacattt cagcgttgag agctgcctca acgctgattt 5094 0 tcttcagcag gcgatcgaac tggctgagat cttcaggggt tttgagattt ttggccagtt 5100 0 cgttagccag agcctgcaac tgtttttcgt ccataaatta acctgctttt gatgttggat 5106 0 tgaacatatc aaaatcaggc aattacacaa atctatgtac aggctcctca gtaaatatca 5112 0 atacggttct ggcgagccgc ttacgatgca tgagaatcac taatagtatg taattattac 5118 0 attttattta caatgctgtt tctgttggtc tgcatccata attatgaaat gctgacttat 5124 0 ggtgtcaaaa taacacatat tcctttcaat aatcatttct tttactatct tttccctgct 5130 0 gagagggtgg ggtagatgtt ctcttgtgag attcatgaac gcagacttat cataaagagt 5136 0 gcatatgttg gagttcagtg cattcttgac aaaaacccct ttttctggaa cgcataatgt 5142 0 tattgggcac ttaagaaatt gtgtgtcgca agagaattca tcaggattta caacaaatga 5148 0 atgagaatgg attttatttt taagggcgtt ttcggcccct tttttccatc ctatatttga 5154 0 agataattga agcataaaat cctgagatat ttgtgcaaaa cttcgtccgt tgttgatctg 5160 0 ctgttccagg ttgcgagcaa tagtgttttg tctcgccata aatatggaga aatgattact 5166 0 gcatacagga tttactgtaa aaccattgac tgattcgata taacggatat ccattttata 5172 0 acgttctttt atgattacag tatcattttg attttgctgc acaatataac gtaaagatgc 5178 0 tagctcattc tcaggtaaga tacttcctgc tgtgaagttt aaaaatatag gcatgttttt 5184 0 tctgtaatac aagtcgattg tttgtgattt cgcgctgtag gtatattatc attcatattt 5190 0 aacttcctaa agtatgacct cgtagggaga taaatgcaat acttaaaggt agattgaaat 5196 0 gataaattag cgcttggtaa atccagaatt tcataaagag agaggtggtg ttttttcata 5202 0 gcgctgagat gtaagttgca acatgtatta tatgcaagag aatagggagt actggataca 5208 0 ttaactctat gtaatccatt caagatatta atgcaattga aataaataag aaactctaac 5214 0 tctctcccct cccaggagaa atccaccaat ctgcccttcc attacctgct gacgcatctc 5220 0 cgccatctca ttcgcgaatg aagtcgatga tatatatgat actaatccag gcattaccat 5226 0 attccttcat acagataaat atttcctctg ggcttcataa caaacatctc cctgacatga 5232 0 caacaaaaac cggagccgga ctccggtttt tgtgaatccg tcggctattt catcccgcca 5238 0 atatttcccc gtcagcacgc cagatttgca gcggcctcac cactcactgt atatgctttt 5244 0 tagctgcatc cagtacacca attaccacat ccttataccc tgaacatctg tagcatttca 5250 0 tataagcaac tggcagttaa catatagctt gggtaatatt tatttcactt atcctttatg 5256 0 acaaagtttc ctttggtttg gtcataaata cattgttctt gacttacaat cattgatgac 5262 0 gttattggtt ctcgtgttag cgggtgcttc ccaccgtcgc gaaccaaatg agaaaaagaa 5268 0 accgaatcaa ataaggtaca aaccaaagaa ccttctgaat ttttaacaaa cacaccttct 5274 0 tctggtttat ccagtataat tgggcatcga accgcctcgg atggacactg aaggctctcc 5280 0 gtattaacag aaaacttaca ttgtgatatt ttcccctcaa tatcaccatg tgattgtgtg 5286 0 ttacctgaac ctgaaaccat tcttaacatt atatccctga gcgcttcagg accaccatta 5292 0 agccctgtaa gtaataatcc agaaagcaaa ctgttattgc ccccactcgc cagaaagcga 5298 0 ccatccgttt cactatatgt gatacggacc gtctgcccgc ctactgtaat ttctccaccg 5304 0 ccactggcgg ccatttgagc acgaagaacc tgcattcagg tggaaaatga attggatgca 5310 0 atagctgatg ttaacggcat gacaaaactc cctatttaaa tattcattcc aaacacaggg 5316 0 agtcataaca aacagccccc atacatgaca acaaaaaccg gagccggact ccggtttttg 5322 0 tgaagctgtc gggctatttc atcccgccaa tattttccca cgtcccgtca gcacgcagga 5328 0 tttgcagcgg tcttaccacg cactgtatct gctttttatc cgcatccagt atcaccacct 5334 0 gcgtgattac cctgtcctgc tccgggataa taccattctc atcggactcc agaatgtctg 5340 0 ccggtcccag tcgcagctgt gctgtaagta actccccgtt ttcacggtca tcatgctttc 5346 0 cgcaaccgca cagacgctgc ataatttttt ttaatatgtt catgtcattc tcctgttctg 5352 0 cctgtatcac tgcccacttc atccagcccc ttaacatcct gccacggccc gtcaccaaac 5358 0 ctgacctgca aatgctgaaa aaaaccctga acccgtgtgg catctttggg gtcaagaaag 5364 0 gtcagtccgg tgatgagtgc gccatctgta tccgggaacc agccatggct gtttgtctca 5370 0 ataatgtttc ccggccccag acggaaccgt atttgcgtct cccccgggtc gcccttcggc 5376 0 ccctgaggtc cggttgcccc caccgggcca gccgcacctg tttctccttt cggtccctgt 5382 0 gggcctgccg ggcctgccgg gcctgccgga ccagcatcac ctgccggccc cctttcaccg 5388 0 gttgcccctg ccggaccggt gtctccacgc tctcctttat ctcccttcgg cccctgagga 5394 0 cccgcgggac ccggttcccc ctttggcccg ggaggcccca ccaccgtggg gattcggttt 5400 0 acggcctctt ccgccgctat cctgctttgt tccgctgact gtgcgctttc tgctgactcc 5406 0 cgggcttttt ctgttgcggt cgttgcatcc ctggctgcat taccggctgc actttctgcc 5412 0 gtcttttttg acaactcagc atctgctgca ctttgtgatg actcactggc tttttgagcg 5418 0 gccgcagagg ccgaggacga ggacgcctcc tctgactgct ttgcagcggc tgcactttct 5424 0 gccgcctgcc gggctgactc cgatgcatcc cctgctgaag tgtcagcatt tgccgcgctc 5430 0 tcttctgcct gactggctga tatgccggca ttcctcgcgg acgtctccgc ctctccggca 5436 0 ttcttcttcg cctcctcagc gtgacgcgcc gcttcttcca ccatcagttc aaaacgacgc 5442 0 agtgcctccg gccggacgtc atcctccgac atggcaccga gaaaatcatt cagcgtcccc 5448 0 ggttgagaat cttcatacac ggtgatggtc ccggcatgtg acggcgggaa cccttccacc 5454 0 aacagaataa cgctgtactg accgtactca acgtccatgc tgtaacgacc ggcttcatcc 5460 0 ggattttcag aggccaccgt gttcaccacc accgtggcgc tgttacgtct ggctttcagt 5466 0 tgaatggtgc agttctctac cggttttcct gtgccgtctt tcagtacacc tgaaatcttt 5472 0 actgccatat tcaccccaca aaaaagcccg cctgaaccgg cgggctgtca taacactgtg 5478 0 ttacctggct aatcagaact tataaccgac acccacgatg aaaccgtcag tgcgccagtc 5484 0 gccactgccg gagccttcat aagcaatatc aatggccacg gattcggtcg ggttaaactg 5490 0 cacgccagcc ccccacgcca gagacgtgtt gctgtggcga ccgtcatcac ttccggtcag 5496 0 cacatcgtgc gttttcccct tgttgtcagt tacgcgaaga taatccccgg agaaagtcga 5502 0 cacacggctg taagccacac ccgccatcgc atacgcgctg aaccattcat tcacgcgcac 5508 0 agacggcccc gccattacgc tgaaccagcg gttacgcacg gaatcttcat gccagcgggt 5514 0 atcgctgtaa cgggtaagct ggcgattctt gtctcctgca tagctgaatg acgtcaccag 5520 0 ccccagcgtg tccgtaaatt cataacggta tttcacgtta atcccgttaa gattatcgct 5526 0 accgggagcg ctcgtccggg catgaagata ccccgcgctc agcgtggcct gctgctcaga 5532 0 cgcccatgca ggcgcgccgg atacggccag acagatggct gcggacaaaa tggcggcata 5538 0 aagtttacgc ataattacct ctcgcttttc tgcaataaaa aaggcgccat ttctggcgcc 5544 0 cgtatatggg ttataaaatt cagctgatac tgatgcctgc ggtggctttc ttcatcacca 5550 0 caaccagcaa atcgctgata cttgctgtgg gataccagtt attcaccagc catgctgaca 5556 0 ccgaaaactc cagcgtcatg tgaccgtgac cggcaggcat atcaataacg ccactgtaaa 5562 0 tcagcgtatt atccagcgcg gtacggttat aaatttcagc accgtttttc cgcactatca 5568 0 gacggcatga ggagtaaata tcagtatgct ctctctctca tgtttagcgc cgctgaatgc 5574 0 caccgccgga ataacaatct gccggtcaaa cggctgatcg tcataaaccc tgacggtaat 5580 0 ggtccctgat ggccaccgtt ccggtgcacg ggagtcccgg gggaaagctt tgcccactgt 5586 0 tttaacgaga tcgccttcaa tctggttcgc ggacagtttt cccagaaccc gacagttctc 5592 0 gttaatcgtg acgttgttga gcgtcccgga gttcgcattc acactgccac tgatatccgc 5598 0 atttttagcg gtcagctttc cgtctgatgt cagggaaaat gccggaggat tgccgccact 5604 0 ggtaatggtg ggagccgtca gatatttcag gaacacttca ttcataaata tctgatcgcc 5610 0 ctgaccaaca aacatcggct ttgtgttgcc attcgcagga ttaatcatcg caatcctgtc 5616 0 tgccgccagc agcacctgac tctgcattcc tgctggcgta ttctcaatac cggcaccgat 5622 0 acccgcaata taaaggcgtc cgtcctgcat ctgctgcagt ttcacggccc acatgctgtt 5628 0 caggttatta tttgtatcaa cctgaacttt ctgtatctgc tggattgccg cactctgatt 5634 0 ttccagtttt ttattgacgg tctgcgtgat ttcattgctg acattcgtaa tggacgtcct 5640 0 gatttcagcc aggtccggcg caagctgacc gttatcaatc tgcgtccaca gctcctgggc 5646 0 cagatgtgtt ttcccgattt ctcctttgaa aaaatccagg taaccttccg catcatcgct 5652 0 cgcccgaccg acagcctcca cgaatgccga tttgccaaca gtattcacac tgcggatata 5658 0 aaaataataa tcatggcccg gtttgatatt gatactggca gctatccagt acagcgccga 5664 0 gccaagatag cgggctgcgg tttcaacctg cctgatatcc gcaatccgct tttccgagaa 5670 0 ccagaactca aactgtaccg tcgggtcata aacggcaaga tgcggcgtgg cggttatctg 5676 0 aaaatagccc ggcgtcagct caatccgcga cggtgctgcc ggtgcggcaa tccggaaggt 5682 0 ggtggtggca ggttcaccct gctggccata gctgtttatc gcccgcaccg tcagggtgta 5688 0 ttccccgagc ggcaggccgc tgaaacggtg ctccgtgtct gcggtgatgg cggtggtcac 5694 0 cagtctggca tccgttccct taccactggt caggcgcaga ctgaagcgca cgcccttcac 5700 0 cacccgcggc gtgtcccatt tagcctgcgc cagatactgg ccgtcagctg cactcacctc 5706 0 caccgtcagg tgctgtactg ccggtgggat gacgctgttc agggaacctg actgcggctc 5712 0 aaagcgggca ccgttatcca cgatggcttc tttttccggt acgtgctgca ccgccgtgat 5718 0 ggcaaaggtg ccgtccgtgt tttcccggac ggagacacag cggaacaggc gacggcacag 5724 0 tgacggcagg gagagtcccc acaccccgta tgtctccaca ccatcaggca gggtactgac 5730 0 ctgtatccgg tccggcgcgg ggtgtgcggt gatgtccaca ctcaccggct taccgctgcc 5736 0 gttaatcagg ttcaccgtgg cggcaccggt ctccggcagt gtcacctcac ggtccagcgt 5742 0 cagggtgcgg ctggcggcat cgatggacag gacacgtccg ccggtcatgg tcccggcata 5748 0 gtcgttatca cagatttcaa taatgtcacc gggtgtgtga cgcagcccct gtgacccaag 5754 0 cgtgaaatcc accgtctgcg tttccagcag tccggtcttt atcacccaca gcccggcacg 5760 0 gtgggcctga ccgcgactgg tgcagccgaa cgcatccatc ttcagcaggt tgcgtccgta 5766 0 gcgcagtatg gcttccgggt cttccaccag ttccgtggag gtctgccagc cgttctgcgg 5772 0 gtcggtgtaa ttcacctcca ccgccgtgtg gcggtccttc agggcgctga agctgtagcg 5778 0 aaaccccacg ccgttatcat ccaccaccac atcactgctg gtgtaggcca caccacatct 5784 0 gacggacggt cctgcacaaa cgtcagcgtc tgcccgttcc ataccggcat acagcgcatc 5790 0 gccgagcaga aatcactgag aacgtcccac gccttacgct gttgtgacag gtacgcattg 5796 0 aaagtcatcc gcggctctgt gcccccgaaa ccatccggga ccgtctggtc gcagtactgc 5802 0 gcaatggcat acagcgccca cttgtccaca tccgccgccc ccaggcgttt tcccattccg 5808 0 tagcgcgggt gggtcagcat gtcccacagg caccaggcag ggttgttgct gtatgccggt 5814 0 ttcaggctgc cgtcccagat gccgctgtac gtgcgttttt ccgggtcata gtttgacggt 5820 0 acctggatga tgcgaccgcg gatatggtag ttcaccgtca tctgctgacc gccaaactgc 5826 0 tccgcatcca cctgcagccc cacaatcgcc gtgttcgggt agcactgttt cacatcgatg 5832 0 atttcggtgt atgacgacca gagcgtctta ttctgcagct ggtccgaggt gctgtccgct 5838 0 gtctcccgga ccatccggat gttaaagggc cgctcaggca gattatccag aatcaccgac 5844 0 gccagaaact gcgaggtggt cttgccgtta atggtgacat ccttttccgt cacccagtta 5850 0 ccgttacgct gcaactgaat cagcagtcgg acagaagagt gattacggtc gccctttgag 5856 0 gtggtctcca acagtgactg caccccgaag gtgacccgca ggcggtcaat gttcgcggac 5862 0 gtaatggtgc gcgtcaccgg ttttgccttc gtcacttcca cgcccagtcc ggtttcagct 5868 0 ccggaggact caaagccttc cggtggtgtc tgctcctgct ccccggcacg ccagaccgcg 5874 0 gtcacaccgt gtatcacggg attgccgtcc gtgtccgtca gtggggtttt gttcaccaga 5880 0 atactctgca gtcccttcac cggaccttct atcggtccct caccaatcgc atcaatcaca 5886 0 ctcatcatct gcgtggattt gagattatcc ttcgcctcac gaggcgtgtg tgccttaccg 5892 0 ccaccttttc ccatacagcc ttcccctgaa taaattaacc gccacttgcc attccgtaca 5898 0 gaagtcggat atccttcgcc cgaaaagcat gaaacacatt tctgccatgc taaagaaaac 5904 0 cccggtatca gcagataccg gggttttctt tcatgcccac cgataatcct gttggttaaa 5910 0 accggtaatg gcataaaaat tctgaatatc ttcacatttt cacacactga ctgtggcgct 5916 0 tataatttcg ctgcgttagt gtttttttgc ccgagtaaca aaaacaactc cttaacattg 5922 0 atcttcattt gtctgtcccc gcagctccgc gatcactgcg ggattttttt atgttttatc 5928 0 cctgtcgccc gacaaccacg accgttccgc ccccgccttc atcacgggtg ctgatgtcct 5934 0 gggatatacg gcgggagcca accagcattt ccccgtaagg caccggcatc gggttcccct 5940 0 gggcaatcat gttatccagc gaggaaaagt acgtgttctg tctgccgtta tccgttgcgc 5946 0 ggtaatccgg tgtttttgcc ttcggggcca gcatctgggc cacaccgccc agaatcatgc 5952 0 tggctccaag tgaaaacagc atcgtggtgg cagaaaaacc accggctgcc agggctgaac 5958 0 cccataacgc cattgatgcc ccggcagtga agaaagagcc cacgatggct gccgccccca 5964 0 gcacaatctg cagtccaccc tttccggccc cggccagtcg cggcacaata tggatgaccg 5970 0 ttccctcacc cagctgttcg tgaagacggg cgtacaccgc ctccggtgcc gtgtcataac 5976 0 cggcaatacg tatctggtac cagccttcgt tcatctgacg gcgaaagccc ggcacctgta 5982 0 acgacagcgc ccggatggct tccgctgccg tgttcacata caggctgagg cggcggccaa 5988 0 atcgttgtaa atccccgtga aggcagatac gtgccagtgg cggtgacgcc aggctgaatg 5994 0 cgttcgtcgt tgccattttt cggaatacct ctcccgttta ctcagttgtt caggcagatg 6000 0 gtgaagcagt tcaccgttgc cgcagtatat ggcggcatga ttggccaccg atgcgccaaa 6006 0 gcagcacagc aggatatcgc caggctgtgc ggaaggcagg gaaatcctgt aaaaaccagt 6012 0 cgcctccata ttgtccaggt acaggttctg accattgcgc caccagtcat cctcacgctc 6018 0 aaaatccggc atatcagtcc ccgccagatg ataagcatcc cggaacagcg tgtaacagtc 6024 0 cgtcaccccg tgctcaaagc gccgtcctgt cagatgtggc acacagcgga atttgtgaat 6030 0 gtcaccccgg cagaccagcc accagggcag tgcgcttttt atctgcagcc gccggtcagc 6036 0 ctcgctcagc cagggcagcc caccgggatg actgtggacc agtgccacaa tctccccctg 6042 0 catctctgcc cgcagccagt cttccggtgc gatacgaaaa tacgcctccg gctctgcaga 6048 0 aatattcaca caagggatat accactcccc ctccggcgtg cttatcacga agccgcacga 6054 0 ctccgcaggc gcacaccgcc gggcatgcgc cagaatcgct gattcagtct gtgtcataaa 6060 0 ccgggattta ctgcgaaagt ttattaatgg aaaggaaacc gccaaaatta gccaccatgc 6066 0 tgcgcatctc acacccgcgc atgcacttgc tgcatctgtc cttacggata tccgtggtgg 6072 0 ggttgtcgaa ctcatccgcc actgccccgc ccgtgtaacc acactcatca gagcggtagg 6078 0 tccacataca ggtattcgcc agcataatgc gaccgggaaa cagcgctccg tccgtctccg 6084 0 tcggtgttgc cagcacaaac gaggctgtca tggccgtcag ctctgacatc tgctccacca 6090 0 cccagcggtc tctcagctcc tgctccgggt ccgcttccgg attgcccgcc acaaaattca 6096 0 ccgcatccag aaaacgggca tacacccggc ggcggaccac cgtggcaccc accaggctct 6102 0 gcaaatcctc cgccatcccg gtgacaagac cgaacagatt ggacaccgtc agcgacgggc 6108 0 gggcactgct gcccttcccg ttcatctcaa agccactgcc gtcaatcggg tatacctgat 6114 0 attgccgccc ctgccaggtg accgcctccc ctttttcatt cagctcatta cagaaaaaat 6120 0 accgctcacc gccctgcacc gtcaggtcga tttcccagag caccacccgc ggtgactgct 6126 0 ctgacttaac cgactcgttc aggctttctt catgaatatt ctgcatcagt tcaccacctg 6132 0 ctctatcgtg caactgaaat cactgtaccg ggcattatcc gtgacactcc actcacggca 6138 0 cacaaccctc accgtccggt tatgtttcgg cggtcgccac aaaaaggcac ggtaaccacc 6144 0 atgccaggat aaaaattcat ccagccagcg ccgggttgac tcatccgtca cccggaacac 6150 0 cgcctgaaac gtcttcagtt gaggattcag ccctgtgggg cggcgctgtt cataaccgtc 6156 0 accaaaccgc accctcacca ccgacggctt ctcactcacc tgcatccctt cacgcgggac 6162 0 cagatgcagc gtttttatct cagccactca gcattcctcc gtcacgtcgc atggacagca 6168 0 tcaccgcctg cacccgctgg tcaatcagct gcacaagact gcctgccgcc tccggcccta 6174 0 tctgtccgtt agccccgtca ttctgaatgg caatgtggta gaccggggaa tacaccagac 6180 0 cagcactgcc gttcatactg cccacggcgc gtacgcccag cgagccatcc gccgcccggg 6186 0 tcaggggcat aatagcttca ggtccggctt cccccatcag cccggcccct tttgcaaacg 6192 0 caaagtacgt gggcgtgtcc acaatgctgt tgctgtacgc gctcaggttt gccgaggtat 6198 0 acacgccgcc ttttgcattg gccaccgctc cgcccagcca gtcaccaatg ctgccgagaa 6204 0 atcctcccgc accggacata ccgtttgccg ccgtcttaat tccgttgaca atcgcggcat 6210 0 tcataagaac ttttgatatt tcctgcagta cggatgaggc ccagctgcgc cattccactt 6216 0 tatttccgtt cagcatctcc gtgatgttat tcaccatccc tgagataccc tccgtcgcca 6222 0 gctgtgctgc ctgtgaggcg taatcggacg cattatccac ccagttactg aatccctcct 6228 0 gcagcccttt ctgccagtcc gcacgctgca catccgattc ggcataaaag actgcctggt 6234 0 ccttaaggcg ttcgctcaga tactgcgcgt tctgtgccag cgcctgtctg taaaaatcct 6240 0 cactgatatc cccggtctga tactgagact gaaggtccgc atccttctgg cggaagctgt 6246 0 cgcggatctg ctgcaactcc cgcatgcgtt ccctggctcg ttccccctgc ccgtacccca 6252 0 gcagttcaga ttcatttgat gcacgcgcag ccacattatc attcttcagg gtctcttccc 6258 0 ggtaccgcaa ctgctcccgg attttttgct ggtcaatcag ggccgcattg cgcagcagtt 6264 0 cctgcttctg tatctccgac agggttttca gttcacccag cgctgtctgg tacttcagct 6270 0 tcgccagctc cgtgttctga ccggccagtg ccagttgctc tttctgctgc ttcagcagcc 6276 0 gggaaaaact gtcttccgct ttttccgtct ctgattttcc accccgggat ttgggtttat 6282 0 tcacctcgtt attgcgccag gcttccaggg cattactgat ataacgttgt ctcgcctcct 6288 0 gatacggatc ccccacaaaa ccgaggtcat ccgccgcata ccccagtcgg acgcgctctt 6294 0 tttcttcccc tttcagtctg gacagggcca gctcacgctc tgtttttgtc agggcactct 6300 0 gctgtttatc atccagagtg gcctgtggca gccgtaacgg cacattcacc agtccctgcc 6306 0 gctgctgaag cagttcattc cccagcccca gcagacggtt gaattccgta tactgaccgt 6312 0 tcataaccag catggactgg tacaccttat tctgctctgc cgcctgctga cgaattaacg 6318 0 ccacacgacg gtcttccagc ccggcaagca catcctgaat ggactgcgct ttttcctgca 6324 0 tctgtgccag acgggactgc tcaacggcaa gctgctctgt tgcctgagca agcccttccg 6330 0 ttacggtctt caccgatgtc agatggttta tcatgaatcc gtcaccggtc gtccagcccg 6336 0 ggttcgccag aacatactga tatcctgcga ttttttcctg cagggatttc acccgactgg 6342 0 cctgttcatc aatcagccgg ttctgctctg tcagcgccgc ccgtgttcgt ccttcattat 6348 0 ctgaggcttc aggcaaagac attgacggcg ttttatgcgc gatttcatct atcgtcagtg 6354 0 catactggcg cgcagactcc ctggcctgct cctgattctg gtacagcgtg taccatgctg 6360 0 cagcccccag catcaccagt ccgggtacgc caccaaccag ccccagcgca ccgctcatca 6366 0 gacgtgagcc caccgccgtt gtactgttca gcgcattctg ggcggcgctt ctggcagcaa 6372 0 tatttctgtt caggcgttcc tgtgtggccg ccagacgggc ctctgcagca atctgcatct 6378 0 ccgtcccgcg ggctgccgcc acggcctgct gagcacggta cacggctgcc cttgcccgcg 6384 0 ccgtggcaat ctgcgttccc ctgaactgtg cttccgccag tgcaacttca ttacgtgcag 6390 0 ccgtcacaag tcctgccgtg gcagacatcg ctccggaggc catattgcca aagtaccggg 6396 0 caaccccgac ggcaaccagc gcgcccacgg ctgttgccac attatcaatc tgtccggcaa 6402 0 caccgttcag catgccggag agcgtttttg tcaccccgct ggcctcattc gcaccgccca 6408 0 cccaggccat aaaggcgttt tccacctttg tgatactact ggaaaccgtt tccggcatgg 6414 0 ccgcatattc atcacgtaat atccccagct ggctgattaa cgcggggacc actttatccg 6420 0 ctgtcagttt tccgtcatcc gccattgcct tcagatcttt acgggccacg cccatacccg 6426 0 cagccagtgc acgtacgatc cggtcaccac tttcattgac cgaattaaac tcctcaccac 6432 0 gcaatacacc ctgcgccagc gcctgactga actgggtgat caccgagccc gcctctgccg 6438 0 tactggcacc ggagattttc agccctgtcg aaatggcctc cgtcaccttc agcacatcat 6444 0 cagcactgta accatattca cgcatcgagg cagccgaacg ggcaaacagg gccgcattat 6450 0 ccgaaaatgc ggtgcctgtc cgctggctga tatccatcag cactttctgt gatgacgcaa 6456 0 attcatcgga tgactgtgat gcctgtttca gacgggcatt cacggagctc cattcatccg 6462 0 ccagcgaaat caggtgtccg gtggcaaagg caccggcaaa cgcaccggtc attccgacag 6468 0 ccgaagcgcg gatttccgtc aactggctgt gcagctcagc cagagcccgg cgctgctccc 6474 0 tggctgccgc agcagcctga cgtccgccat tctgcagggt ccggtaatat tcactgccca 6480 0 tacgggacgc ccgctggatc tccgactgga atgactgtga atttgccgaa attttgataa 6486 0 tcagttcacg taacgtcgcc attcaccttt ctccgggcgt aaaaaaaccg cctcagcggt 6492 0 tctcatcatt catgactgtg ctgcaaggct cagcgcgtct tccagcgccg caaacggatc 6498 0 cacctccggc ttatcctcat cctcgcccca gcagagcatg gcgtccttca gtgcaacatt 6504 0 catcccctgt gccccgaaaa ccgctttcac gatctgtgca ttacggatat ccccgcgctc 6510 0 atcacccagc ggggatatcc tgtcgaactc catccacatc atcgcctcgc tcgcactcag 6516 0 gctgtggcgc agttcggata aggtgcgccc cagacggagc gcaagtcgca tcagaaagcg 6522 0 aatttccggg cgggctactt ttttctggcc gactctgcat cagcgatcag ttccagtgcc 6528 0 tgacgcagca accgggcatg taccggacca tagacggcca gcacctgctc acggtcgtcc 6534 0 ggagtgaaca cccgctgcag gtccgtatca cacaggacat cgcagaacag cgtcacatcc 6540 0 gcttccaggt tacggcgggt tttcgccacc accgacaggg tatcgtcatc ctctccatca 6546 0 ccattgagca cttcctgcca cagataccag gcctctgccg aaggctcccg cagcaccacg 6552 0 ctgacattac cccattccgg caccttcacc gttttatgac gaaaccctga cagtctggcc 6558 0 agcgccagcg ttttcagatc ctttttcatg atgacccatc cccttatccg gcggctgcgc 6564 0 tcactgtcac ggtgcattca acagacgtca cactctgtgc tttctctgcc gaatcggtca 6570 0 ccacacaggt atatttcccc gcatcagcgg actgcgcacc tggcttactg aaggtgtctg 6576 0 tcgtctgccc gtcaaccggc tgaccatcct tcttccaggc gtatttatac ggcggcgttc 6582 0 ccccgttggc actgactgac attgtcagca gcgcaccggt attcacggta agtgtcttat 6588 0 ccagattttt cacaaacgcc agcggtacca caaaggacac cggtttgcct ttcagacgca 6594 0 gtgagaacgt tgcagccacc acgccgttgg taccggatga ccaggtgtgc tggcgcactt 6600 0 ccgccaggaa tttaaagccc ttaccggacg gaaacagcac cttaaacgca tacaacgcgt 6606 0 cattgtcata ggcatcacgc agggcgttct gggcctgatt cagataaaaa ttgcccgaca 6612 0 tggaaatctc agacgacgcc cccagaccat tgatgttctc ctgctctgtg gagcagagcg 6618 0 tggtcacatc aatatcctgt ttctgcccgg cggtgaactg cacttccttg atggtgcagt 6624 0 ccaggcgcag atattccgcc ttatccatag tttcagcagt cgccggggca gatgaaatca 6630 0 tcacctgcgt cagctgtgag cgttcataca aagcagacat tctgcctcct gataataaaa 6636 0 aacccgcacg cggcggggta tgggttttgt agaaaaaaga aaaagtcaca ccgtgacctg 6642 0 aaactccagg gttgcacggt aacagcggtt ttccggaata tagtcctgca tttcactgac 6648 0 ggatcccggg gccagcagca ttatggcttc acgggcgtcc tgacgtatct gacgcgcctg 6654 0 cgtcacagtc ccggcataaa cgtctatctg caccgacact gaggactccg cctgcccgcc 6660 0 catcacgtcc gctgacaccg atgaaatcag gctgaaaacc acccacggaa gcgccaccga 6666 0 cggcctgcca tccagcaggg ggaccacata cgggtacacc tgcccgccgg caagatgcgc 6672 0 cagatgagga tacaaatccg cctccgtcat cgtctcagta cctcatcaat ggcccggttc 6678 0 atccgcgcaa tcgccacctg tgccgcctgt tcactgcgca catcaaatgc cgggcgcaca 6684 0 aacgggtgcg gtggcatatt cacggtcccc atttccacaa accgccagta gaaagcgttg 6690 0 cgcgggttat ccgccttcat ggtgttatcg ctgttaccgg tgtccggatt aacaccccgg 6696 0 atatgcacac cggattccat cccgccatcg cgggagcgcc gggaaaggac caccacattg 6702 0 cggcgcagtt ttcccctgcg taccggtgcc cgtgacacca cttcttcttt cagcacattc 6708 0 gcacccgcac gggttgcctc acgcagcacc cggttatttt ctgcaccact cagaagctgc 6714 0 aaatcgcggc tgatgtcctc cagccccgaa aaatccagca gggtttcgat catttttccc 6720 0 ctcccagccg acagagaatt tccagacgtc cgccggtcgc atccggcacg ggcagcccga 6726 0 caacgttcag gatccggtca cgccagggac cactcagcac atgaagtcgt gacgctgccg 6732 0 tgatttcccg accggactga ccgcgcaccc agatgcggat ttccgcctgc gccatttccg 6738 0 caccggactg catccgctcc cggctgctcc tgccccggat atccgcatga attttcccgc 6744 0 atgacaccca ttcttccgtc atttctccgg cagcgttacg ggttaacacc gggttcagaa 6750 0 cacttatcat ctgtgtcaga cgacctgcag atattgccat tccccctcct cataacaccg 6756 0 tcggacaacg caaatcgtaa atcagcacgg aaacagaaaa cggcagctcc ccctgaatca 6762 0 gttcttcccg ctccgcaaga tccggattcc ggtacagcat cccggtcagt cgcatggcag 6768 0 cccccttcat ccgggttaat gcctcgcccg ggatcagttc accgtcctca cgaatcacct 6774 0 tatcccggct gccctgaatg taggccagca gcacggcggt agcctgacga accttgtcca 6780 0 tcagcatgtc atcatccgcg tcatggtcga cacgcagatg tgccttgatc tcttccagtg 6786 0 tcagtaatgc cgtcattttc agcctcctgc atcccgccca cgttttgcag ccagggtcca 6792 0 ggctgatgaa tgagcttctc cgggtttatc ttcggtcata ctgttgcagt gccacagcga 6798 0 gcccccccac gtcaccgtat cgccggggtg gtaggtttca ccggctctga acacaccgcg 6804 0 gtagagcatc accggcaggg aaaatgtttt ttccgtacgc tggccactgc tctgccggac 6810 0 caccacagag aacaaccgct cacccgtcat gctgacgtca atatccgcca ccccgtcaac 6816 0 caggcattcc catccccgca tcccgtgcgt tttttcatac gcccgccaga gtccgccctg 6822 0 gtgtgtggca tacgtgcccc ggggaaagga tttttgatcg tcaatggcgg ggagtatttc 6828 0 cagtgccgtg gcatcacgcc cgtcctgcgg agccggcagg gcactcaccg catccagaac 6834 0 cgccttctgc agaacatccg gatcgtagtc acgaccatca cgcggaacag gaatatggct 6840 0 taccgcctcc ttcaccatct gttcaagcat cggacgcaca tcatccgggg tgagactttt 6846 0 accgtctgcc ggctgcggaa tatttgcgac cgcatcattc accgccttct gcagtacttc 6852 0 cggatcatag tcacgaccgt cgcgcggaac agggatatgg cttaccgcct ccttcaccat 6858 0 ctgttcaagc atcggacgca catcatccgg ggtgagactt ttaccgtccg ccggctgcgg 6864 0 aatatttgcg accgcatcat tcaccgcctt ctgcagtact tccggatcgt agtcacgacc 6870 0 atcacgcgga acagggatat ggcttacagc ctccttcacc atctgttcaa gcatcggacg 6876 0 cacatcatcc ggggtgagac ttttaccgtc cgccggctgc ggaatatttg cgaccgcatc 6882 0 attcaccgcc tgctgcagta catccggatc ataatcacga ccatcacgcg gtaccggaat 6888 0 ggcccccaca gcgtcatcca ccatcgcctg cagaaccgga cgcacctcat ccaccgtcac 6894 0 atgcttctgt aataccgccg acagggaagt cagtttctct tcaaacgctt gtgcctgcga 6900 0 ggccatcttc ccctcaaatg tgcgctgtaa atccgccagc actgtggaaa attcttctcc 6906 0 cagtgcacga ataatggaca gttcccgttc cgtcattttc tcagtatccc ccctgaacat 6912 0 cgctttcacc gcatcatgct ctgtttcact gattgcctta ttaccgtcag atgcgccgtc 6918 0 aggcagctgt gatgaaactg ttttcccggc agacgcgaac ggatcctcac gggcatcacg 6924 0 acgggacagc gcctccagac tgtagttctg ctgctgaaga tacagtgcat caccgccggc 6930 0 caggggcggc aggttctccc gtttacgggc ctcattgggc gtgagaagcg tatttttcac 6936 0 cgcatccccc agcgttttca tgcgccgctc actgtccatt ctcagcagcg tggtgacatc 6942 0 aaattctgta ctctcgtttt cccccgtttc cagcgcctca tccagtaaca gttcaatgga 6948 0 ctcaatcagc gtctgcagac actgggaata atactgctgc tccagcgcct ccacgttgtc 6954 0 actggaaggc gggtggccaa cgccaatctt gtaggccggg acacggaaca ccgaacagac 6960 0 aatttcagcc gtcattttca gttgttccac cgtctgcgca tccaccggtg aaaacgtcgt 6966 0 ggggctgtat tttgccccgt tgctcagtat ggccgtcttc ccggcatttt cgcccgtata 6972 0 tccgctgtcc cagttcccct tcagtttttt cgcgttttct tccgtaatac tgccggggac 6978 0 ctcaatcacg cctgatggtc gcccgccatt tctgaaaaaa tacgtcgaat ttgcctgaat 6984 0 atgatgcccc tgcatggcgg ccagtcctgc ggcatacacc ggcggcagcc ccacaagcgg 6990 0 atgaaaaaaa cagttaaaac ggtcgtggat cacctcccgg gcaggcaccg tcaccgactc 6996 0 tgtgatccca cagttccggt ccggcgtgat gcggtagaac acctcgccgt catccgccac 7002 0 cagaggttca acccggttcc agtccagaat acgcagttct ttgatctgcc cccggggggt 7008 0 gcggattttc agcaccaccg tattgccgtg acgcaatttg gaattcagcc acagttcaaa 7014 0 aaactggatg cgattctgct gcgcattagg acgacgacag agacgggcag tatctccctg 7020 0 ccgcttttcc cggcgtattc cctgtacatc agtctgcatc aggcgaagcc gcattttggc 7026 0 aatatcctgg gatatcagcg aaatgcatga aaacaccgcg tgaaaggaca aaacggtttc 7032 0 cggatcggct ttcaccccct gctgccaggc accggcaaaa ggctcagcca ccgcctgaaa 7038 0 cagggaccgc cagcccactt ctcttacgtc acgtcctgat ttctggtttt ttcgggttcg 7044 0 ccgcaaaagg ttccacattc gccatgctcc gcatcacgtt tctttttctg acctgccgga 7050 0 cgtcgcgctg tgatgtactc cgccttcccc aggcgaacca gcacctccgc acacggctgt 7056 0 gccacatcac ggatatcccc ggcccgggca tcatgcgtgc cctgcagata tcggatcttt 7062 0 gccataacct gttacgggag gcgcacgcct cccgtcctcc ttatcagact cagccgccgg 7068 0 acgcactgcc gtagttcact ccggtgatca ccgccaccgc cgcagtacgg cgacgacgcc 7074 0 agttgatcca gcgctccgca cggatggcca cgctgcctgt ctggaacatg gaaaccagct 7080 0 ccaccgggga cggcgtggta ctgtcgccgc ccggctcaga ctgcatttcc agtgatgcct 7086 0 cgcgggacat atccactgcc acgccgccgt catccgccag ataaatatcc ggggcattca 7092 0 ccagcaccag ctggtcaccc acgtactggg agacaatcac cggcagcccc tggaaggagc 7098 0 cacccagcag ggtcatgtcc gggtattcct tctgacccag cgcattttta cgcatggaca 7104 0 gtgccagggc attggtgctg gacatcagcc agaccgcacc ggtgggctgc aggtttgctg 7110 0 ccacaaactg tccaaacgca gcctcggcat ccgcatccgg gttaccggtt gatgccgtgc 7116 0 ccttcacatc atgggtgatg gacgccgggg agacatctgc cactgcggct tttttcgggt 7122 0 ccacaaagtc tgtatccaga cgcgccacca ccgcttccgc cagcgcatta cggaccagtg 7128 0 catcagcagc cggactggaa aaacggatca attcttccgt cagtaccgca atggccgaca 7134 0 ccttcgcatg actgaaggtg atggattcaa aatcaaactt cgtcaggggt tttgccttac 7140 0 cctcacccac ccagccggca gcaccgccgg acacctgggc gtgcacacgg atattgaatg 7146 0 gcacctgacg aagtgcaggg atcccgccct gaccaaatcg cccgataatg gtctgcggac 7152 0 gcaggtaatc aataaagtcc tgtgcgtatt cctgatattc agacaggctg cctgcccact 7158 0 gcggatccgt ggtggtcccc gcgcccactg ccgatttcag gacatgatgc agacgactgt 7164 0 catccggata ctgacgacgg gccacttcca gggcttcaga tcggacgcct ttagccgcag 7170 0 ccagcgattt ggcaaagcgg gcgaagccaa tccccttatc cagtttctgc tccacacgga 7176 0 tcaccggcgc agaagccacc gcggccacat tcccgttacc ggcctgtttc accggctgcg 7182 0 ccgtggcggc cttaccggct tccagttcac gcaggcgctt caggtgcgca tccacctgac 7188 0 ggatttccgc tgcggtgttg tcgtaatgct cttcctcctc cacatccagc gtgcgccctt 7194 0 cctctgcggc tttggtcatg acctcctcaa gggaggctgc cagcgctgca cgcttgtttt 7200 0 caaaactttt aatctgttcg ccaatattca ttatggtctt ttccttatga aaaacggttg 7206 0 ttgactgtgc cgcagcgccg gcagaagatg cgattttcac caccggtttc cggttgccgg 7212 0 acgcggcaga aaacgggcgg tcgtaagatt taatggtccg gatggtgcat tccgcattcg 7218 0 cgggcacggt gacggcagac acctccatca gttcccagcg cagaaaatgc agtccgcctc 7224 0 cgtccagaaa ggtgtattca tggggacgga agcccacgga cagccccctg accagcccgg 7230 0 tcttaatggc cgcccagacc tcatccagcc gggcagccag ttgcgacggc atatccggta 7236 0 cgggcttcac cagtgttgcc gtgatttcca gcccttcgct gacccggcgc accgtacact 7242 0 gccccaccgg gcgggaatgg tcatgctgcc agagaaacgg gatcgcactg ccaaactccg 7248 0 cgccctccgg ctccaggatg tcaccatccc gatccggaga aggcgttgac gcaatcccgg 7254 0 tgatcacccg ttcatcctca ctgaaggatt tcaccgtcag cagggaacag gcccgtttaa 7260 0 gagtcacatc agcctcctga aaataaaaaa accgccgcag cggttcatga tggttacagt 7266 0 gtgaacaggg ttatatgaaa aaaaccgcat attctttctt tttcggttcc gggttaaggg 7272 0 acatcaggga gaccgcattg aacagcgcca tcagcgggtc aatttttccc cgtccactgg 7278 0 cctgtttggt gataagaatg gcgttacctt taggctccac ccgggcattg ccgacacacc 7284 0 aggccatcag gggctggtca ccatgcacca gcaccccttc agccagtttg cgctcggtgg 7290 0 ttttaatggc cccgcccagt ttccagccct ggcttatccc caccacaatt ccgtcgggga 7296 0 tcccggcttc cgccagtgaa tccagaatct gccccacccc tgacgggtca ataccgatat 7302 0 ggtccagtaa ctcagcctca tgaatgcgac gcacatattc cgccacttcc gccgtgtcat 7308 0 ccccgacacg ccggacaatg gtcatatctc cacaggcaac aagatcctga aaccgggacg 7314 0 cctcgctctt ccgtcggacc accgcggttt catgcgccca ggcatggccc cagcccagcc 7320 0 attcgcgggt ttccctgtca cggccaatca cgtacattcc cagcagatca tccaggcccc 7326 0 cgccgtcaat ccccaccgtc accacatcag cgcgctgcag gatatcgtcc aggctgacgc 7332 0 gcctgccctg ctgctcccag aaatccgcac ccgcccagcg gtcagaacgc agggcaagac 7338 0 caatttccac attggcatgt tttgacatga agccacgaaa tgcttcctca ccagcctccc 7344 0 gggctttacg gtactcccgg tacagaaaag cctcatccac cgaataaccg agattcgggt 7350 0 taaccatggc gaggttttcc atcagcaggt gagccccgct ttccaccatt tcaggaggat 7356 0 gctcaaaaat caccggcaga aagtgcggat catgaatttt gccgtcacgg acatcccggg 7362 0 cgtactgcag tttctgtctg aacaccccgg ctggcggctc attcgactgg gtggtcgtat 7368 0 acaccacaaa cccttccggg cgggaggcaa ggccgcctat ggcttcacgt aacatgtcct 7374 0 ccgctttgta ctgcttgcca aataaccaca gttcatcaat cagcgtcccc acggacttga 7380 0 taccggatac cgtattcgga tcggcagcca ccaccttcag ggtggtgtcc gtcaccctgt 7386 0 gggtgatggt ccggatatgt gtctgcacct gacagaggtc atccagatca tcgtcccgtc 7392 0 gtaccatatc cctggcaggg ttgaaggcgt tagccgccac ctccacggtc ggggccagaa 7398 0 tggtgtagcc cgccgcctgc cgccagttca gtaacagcgc cgtcatcatg atcccggcag 7404 0 ccagcgtgga cttgctgttt ttcttgggga taaggataaa aacttccttg atatggcgta 7410 0 caccggtctg cgcatcgtag gagccaaaca gggccgccac caggtcaaac acccactgtg 7416 0 cgcaggactc cccgaacgtc gggctgcccg gtgcatccac aatccgcagt tgtttaaaaa 7422 0 tcgccagggc atgtgcggcc tgctccggat aaatcggagc cggaataatc gacagcccct 7428 0 ttttcaggcg ctctgcccag tccgggcagg ccgtgctcca cacaggtatc atccgttgcc 7434 0 ctcattatca ttattcacca ccaggcgggg tggtggtggc accgcaaaac ggttagccgc 7440 0 ttttttcgcc gcgtcacctt ttgccgattt tttaccggca tccccttttt tgtggtgcgt 7446 0 gaactgcgcc agcttataag ccgcatccag cgccagcctg gggtcggtat taatgttctc 7452 0 caccagaaga cgccccatcg ctttcaccgg atcgggaaga ccgtcctcca tatactcaat 7458 0 accaggagat atcaccacgg gcggtggcat ctccggattt gtttcgtccg gctgtggtat 7464 0 tgcagccgcc tcacggcgac ggggtttatc ctccggctct gattttttct gccgataaac 7470 0 aggaacctca tccacctcca ccgtctcgca ctgtttacgg gctataaacg caagcacctc 7476 0 cggatctttt gccagctgcg agcctttaac cctggctgtc ttcgccgaat aaccggcggc 7482 0 aagggctgac gctgttttgt ttttcccgga catgagcgcc agcgcaaatt ttcgtttttg 7488 0 cgttgtcagc acagcctcct cccgggtcca gaacgcactc agccgggtat ggttcagccc 7494 0 atttttcccg gcgtctcatg ccgcaaatgt taactgctgc ctggttaaca tttgctgaaa 7500 0 aagcctgtta acattttttc cgcacaacaa actgaataat aaagataaaa accgcaaaaa 7506 0 tgcccgggca gccagttaac atgttaactg ccctgaaacg ggaatttttt ctctgcgtga 7512 0 gagggggcgc ggtgtccagg gcgatcgttt tttttcgccg gatgatcccc cccgggtctg 7518 0 gtcacaggcc agtgattccg tcggccctga gcgtgccatc aggaagctca ggcaacgtcg 7524 0 gatcaggcat accactcgcc gcttcactcg ctgacttctg gcgatggcat tcagtacaga 7530 0 gggtccagag gttcgtctcc tcattaccac caccgaactg aagtgcaatg cggtgatcga 7536 0 gttcactgtc acaaaggtca accacgcgtc tacagagaca acagtgtccg gcatccctcc 7542 0 gccagatacg acgtttgagg gaaacccggg cactgccact gacacgacgc tgttcccccc 7548 0 tcaggacatt tatccgccgg gtgttcagag ttttgattct gcccggtaac gtacgaagca 7554 0 cagccatgta aaatcctcgc catatagctt gtcaccagag gaaagaaaat gtcatcgaaa 7560 0 aaccggcccc gcagaacaac aacccgcaac atccgatttc caaaccagat gattgaacaa 7566 0 attaacatcg ctcttgacca gaaaggttca gaaaattttt ctgcgtgggt cattgaatct 7572 0 tgccgccggg agctggcagc agacataaaa tatgcccgtc agttgactat aaaaaagaat 7578 0 gatacacagt atgctctgcg atggctgttc atataactat ttctttatat tgctgaattt 7584 0 ataaaaactc acagacatta gctgtattaa ttccgaattg aaataatcag ccatatagaa 7590 0 taaaaataaa gcataacaat aataatcttc tacccaatca gtacattact gctgtgactc 7596 0 caacacggca gtttttttat tgaacagatt ccagtttctt ccaccatcgc accggacggg 7602 0 cgaccatgag gggagaacgc cgcgctccgt ttacgcggta aaccccggtg tgtatcgttt 7608 0 ttgattatcc ccgcacactc tcgcagagga gtctccctgt cgggctgcgg tctctgttaa 7614 0 tgcaggaata cggcgacgat acggcgcatc agcaaaactt agttcaggca ctgagtgcgg 7620 0 atatagtcct gtgccccttc cagctgcttc tgcattgtca tcaaccgttc tctgaggatg 7626 0 aaataatccc gttcagcggt gtctgccagt cgggggccgg ttgcattatc cacgccggag 7632 0 gtgccggtgg cttcacgcac ggtaccggag caggtggcgt tgatccgcag gcgcttacga 7638 0 ccagcggcaa catcagcacg cagagtttca ttttcagctc tcgcatcggc taactccctc 7644 0 gagtattttg catcgagcgc agcaacatca cgctggcgca cctgcatgtc agtaatggtg 7650 0 gcattcgcct gttccagctc tctggctttt ttatcgcgct gcgctttgta ggtgagcgcg 7656 0 ttgtcacggt aatggtttgt tgccagccac agcgcaccat agccaaccgc caggacaata 7662 0 atcaccacac acagaacacg gttcatctct ctttcacccc accagtcccg ataacgtcag 7668 0 gactcgccag gcggtggaaa agaaaatggc aaccagcatg actaaaaatg aaatgccgac 7674 0 aagtacacag aggctcttca ccagcgttat gagtttatct gatatcatta gccaccccat 7680 0 caatccgcct ttgttatttt ccctttgcct gtatcagcca ggacaaaatc aatcagcata 7686 0 ttcgcttcat ttaccagcgt acggattttt gatacatgcg cggctttaac ctgtttccac 7692 0 tcattcagcc cggtagcaaa cacactggca atgtttttat cccgtttcat gtcagcacaa 7698 0 gcctggttga gttcttccat cacgctcatt ttacggggat taacgacaaa acccttcgtc 7704 0 cagtactcgt aaagaacatc gtcgcactct tcctgatacc ggatgacctt atcgcggatt 7710 0 tcgggtttta ctttgttggg attaatggtt tgtagccagc cggcaagttt tcgaagtggc 7716 0 atggacacca tattgcgttg tttcccatcc tcagcaacca taacgatttc cgttatagtt 7722 0 gacgcaaaac gctgtcttaa cttagccaac tgtgattgcc aggccagccc catccccgca 7728 0 acgacaggtt tcatgggaac gtatggttcg ccattatggt taactacata aagagagttg 7734 0 ccgtgaaacg gcacggccat catattcatc ggttatttcc ttttagtgat gaaccttgtc 7740 0 tcacaggaat ccagcccaca gaaaggcacc gacagccaaa ccggtatcct caagggtcat 7746 0 cctgaaaggt tctgtgttgt gagatgcgcg tgagatgcgc agaaatgaca aaggcatcat 7752 0 tacggtgcct gagtgttaaa caactgcttt gactttattc acttacattt tgccaatttg 7758 0 caggatttcg tgttatccgt ccatgtaagc aaacctcatt tttcagcaaa atattctgct 7764 0 tatctgtcga ttccccagca cgccagcgcg ctctcctggt cacgacggga tacctgaccg 7770 0 taacagttat ttgagcgaat acggcagtcc ctgccaccgt ccttaatcca ccagcgaatc 7776 0 gcttcgcagg caccttttcg atctcctgca ttaatccgtc tgtaaaacgt cgacgggaaa 7782 0 cacttaccgg ggccaatgtt gtacggacag aatgacgcga tccccgcttt ctggggttcg 7788 0 gtcagcggca ctctgatgtt tttctccacc catgccagcg ccttatcacg ctcaatggcg 7794 0 ttaacccggt cgcatttttc cttcgacagc ttcatgccag gaataacagg cttaccatcc 7800 0 ccccgggtgg ctccacggca gatggtccag atacccgcac catcacggta tgctgtggtg 7806 0 tggttacctt ccttttcatc cagaaactgg tcgaggattt caggcgcaga cgcccctgca 7812 0 ccaatcagcg ccagaacggc agccgacagg ccgtatctga tttttgcgtt catggatatt 7818 0 tatcagggtt tatcgatttc aaatccctgg atatgttaag tcttcaggcc agcggtggag 7824 0 tcttcagaga acccgtaatt attcccggta gttttcctct gtaggttatc aacacatcct 7830 0 gcgcctctaa aattacgggg cgcttttccg gcaacggacc atccccttca cataacccgg 7836 0 cagcaacatc catgaaaaac tgcttcgcct gctttttcgc ctcagcttcg taaaactcca 7842 0 gcgtggcacc ttcagtacgg tcaagactaa tcgccacatc tggcaacaac agtgacggat 7848 0 acccaccaat ttccggtgcc acagtaacag taatcttatc cgggtaatta tttatccctt 7854 0 taacaaccag ttcgtatttt ttcttcatca ctttactctc cccgcgccgc cttacgccgg 7860 0 tcttctttaa tcttgaaata caggttcgtc agatatgtca gcagcccaaa cagcagactc 7866 0 cccagcacgc ctatcgccac ccactgggac ggagagactt tgtccagcag ctgcagtaac 7872 0 cagtatcccg tccccaccgc tgacgtggtg tatgacacac ctgttgtgat tttttccatc 7878 0 tgatgtatgt ctccgtcacc gccgacagaa aatgaaagta aagaaaaaca aaaaagccgc 7884 0 cagtgtcacc cactgacggc caacgccggg agccgtgatt atggcattca ggctctgcta 7890 0 aaaatgccag ataacattcc ggccaccccc tgattcaggt tataaatgac acaatatctt 7896 0 gacaacaccc gtcactgtct gtcagaaaat ataccgccag gcataagtat catgtgaaat 7902 0 ccaactatcc ttctgagcca gcacctctcc accgaaagtc agtgctggct gtttttttcc 7908 0 ttaataaagc atctgtaact gaaacaatcc gcatattgat aatatattga caggcatcat 7914 0 tgctgtctgt gaaaaataag tctctacaaa catataaggc cttttagcca gcgtcttctt 7920 0 tcaggtcagt cgctggctct ttttttatta tgctgccggt gcatttatct ccagcaccag 7926 0 actttctatc tcaacgccat acgctgcatt ttttgtaaca tccgtcagcg tcagcgcatt 7932 0 cagtcccagt gtcagactgt cttttataac ctggaatgcc gggccagcca ctccattcag 7938 0 tttcggagta accgtggcac tgccggcggt gaacaccagc tccagcgtct gccagtcgtt 7944 0 accgtaatcg ccgaactccc ccagcttcgt gtttccggct ttcctgtgat gcatcagatt 7950 0 cactctgccg tcagtggtct gagtaaagta cgacatcagg aacggattac cggtacccgt 7956 0 catcgccaca ccatcaggaa cgggagcatc cgtatacaga taaatcccca gcccgaactg 7962 0 attgttggtc agcgcgcctg acaggcggaa cttacaggtc agtctgccgc cctgtgtcag 7968 0 cagggtaatt gcgtcatcca ccggatgcgt cagggaccag gttttattgc tctgcctggt 7974 0 gatcttaaat acaccatctg acaactgaat tccgccatcc ttaatgctcc agccctgcgc 7980 0 agcagcctct ccggctgccg gcagcaggga gattgtgcga acggacgtat ctgcagacgg 7986 0 acccgatggc gtgttgccgc cgggcgaggg tttgatttcc ggtgccttac cactgatgaa 7992 0 ggctgaggtg cgcccggctg cgttcagaat agcggttgcc agacgatccg gaataatgct 7998 0 cctgcgcgcc catgaactga aatgtgtcgg gcggtttgat gatacctggt ttccattcgt 8004 0 tctcgatgcc gcaccgtaat atcctgatgc cggaatatcc ggatcttctg ccggcgcgtt 8010 0 agtggcggta ttgacgccgt taccgtctgt catgaagggc acaaaataaa cgccctcact 8016 0 ctccctgttt ttatacccgc cgtacacggt gtcgtactgg gtagcgtatg tatttttcca 8022 0 gtaatacgtc gtgtcaccac aaatccacgg cacatctgca gcactgccac catggcactg 8028 0 cgcgttaaac acggagaggt cagcacgaaa ctgtgccagc atggctgtaa acagcgcagg 8034 0 ttgctgtgcg tgggtggcgg cgctcatgtc aaactctccc tgcatccagc agacggccag 8040 0 cagaacgttt ttgggatttt tctgcaatgc cgcttttgtg cgggaaatca gatcctgata 8046 0 taacggcttg cccacccccc agcgtgccga atcctggctg gcccccgtgg actcgctgaa 8052 0 tgtcccctcc gcgccctggg taaatgccga accaccacga cagcatggta ccagcaggat 8058 0 ccccgcgtta ttcgggatat acgggagcag ttttttggca atatgtaacc cctggccgac 8064 0 acagccgtac tgccctttgc tcaggtctgc cttcggatga ttcagcgtac tcatatcctg 8070 0 cacatcatgc aggcagtggt cggccggaat aatatcgtta tatctgcagg cagccccacc 8076 0 cggcgtcact gtactgcggc gcgccagctg tttaatgcgc ggatccggag catcgtatga 8082 0 atccggcagc ggaagccctt caccgtaagc catggcattg gactgcccgg ccagtacgat 8088 0 gacgtagtac caatccggct cagttgcacc actgaccacc acatcacctt ctgctgtaat 8094 0 cgcctgcatc agggtataag gggttatggc caccggacta ccaaacggct gccagccctc 8100 0 tttcagtttg tgtgtcagct tttccgcaag gtctgacggc gacgccgccc tgacaacatc 8106 0 ataatgttta atcgacatcg aatttctccc gtgtacagga acagagttaa aaagccggaa 8112 0 ccggaatcaa atcacaggat gaccatctgc cagtggctgg tcgtaaaaaa aaggccgcgc 8118 0 catgcgcagc cggaaataaa gggataacga tgatagtttg agaaaaacag aaataacact 8124 0 tttgtggcaa agcatggtgc cgggtgcctc ccggtgaatt cagtaccagc acctgaatcc 8130 0 gcgattatcc catatacctt cttgctgatc gcccctccgc acagggggat tcaccatgca 8136 0 gaagtgtttt taataaacag caaacaaaaa aatcaagcat tatgcaggct gtttcttttt 8142 0 atcaccggcc acagcaatac cacaatgccg cagaccagca ccccatccgc cagcaccgac 8148 0 atgattctgc tggtgaaatc caccatcacc accagaaaca gcaggagtgc agccacagtc 8154 0 aggcgcagtt ttaccgtcac aggtgattct ccagacgaag acccagaaca ccggcaatct 8160 0 cttccagcac cttgcgctct tccggctcaa tttcgccgtc tgcctccgca atggccaccg 8166 0 ccacatccag cacatcttcc gcttcacgcg tatcgtgttt cacatcctcg atctcacgta 8172 0 acgccgcacg acgaccagtt ttaaagttcg tatccagctg accgataatg gttgcgctaa 8178 0 tcgcattaat ttctgacgta aacgcggaca gcgcaggctg attacgcagt acctgttcga 8184 0 tcttcgcttt ctcggatgcc tcacattcac catctgcaca ggccaccagg tatgcggcgt 8190 0 taatcaccac ctgtgccaga tcgcgttttt caaacttttt aatttccgtt gccgctctgc 8196 0 gggctttttt taccaaaaat accaaacatc gtgacgttcc tttgggtggg tgagccaacg 8202 0 cccgggagcg atctgcccac agagaaagtc acactgacca ctccgtaagc tccccccccc 8208 0 ccccgaaagg ctctgtggtt ggtatgtgcc gggcgtggcg cagatacaaa aaaggcccgc 8214 0 aaaagcgagc cgggaaaata agtgtggcgc gttgtactgg agtcgaacca gtgaccgatt 8220 0 gcttagaagg caattgctct gtcctgctga gctaaaaacg cagaataccg ataatggacc 8226 0 gccatcggag actcgaaccc cgcgaaacca gcttcgaagg ctggcgttct atcccgatga 8232 0 gctaatggcg gtatgtgatg gtggcccttg ctggatttga accagcggcc tggcgattat 8238 0 gagtcgctcg ctctcaccac tgagctaaag ggccgggcgc aggataataa cgttacgaaa 8244 0 tcaatgttgc aagcattcaa gaatcacctg gttaaaaatt acccttactt cctccaccag 8250 0 cgcattcacc atgtctatcc gagataagtg gcacaaaaaa acccgcttgt gggcgggttt 8256 0 tgtttgcttt tgccatcacg tacaaaatcg gcaaaatatc agatttgcat gaaatatatg 8262 0 cctttcaatc tacttttgca acactttgct ttgaaaatgc cgccttttgt tttgaacgcg 8268 0 ttctcattac aaacaataaa gcctcactat ccagtcggtg aaaaatgtgt ttcattgcaa 8274 0 cccagtgacg agtaaatgtt ttggaccagt ttttagttgt cactcccacc agtaatgcca 8280 0 gctccttgta ttcataacct tccccaccaa aaagttctgc ttttactgcc tgcgccgcca 8286 0 gccagattaa ttttttcagg cgttcctgcg ttttccctgc aatttttctg gtaccggatt 8292 0 gagtattaaa ttcattccac gcccactgtg ttatcgcgat ctgatattcc caacaaatac 8298 0 tcccgctgta acaccacaac aaccaggctt tatgatgttc ttcaagagac agaacagccc 8304 0 gccgccacga tgatgtcgaa aactcaaccg gactgaccag aggaattgac gtcaccttcg 8310 0 ccagcgattg ctttcccggg attggtggat tatcccgcgt tatcattttt ccagtcactt 8316 0 catcgcggta ccggattttt tttcgcctgt aacgccctgt atcgaacatg gcattctcct 8322 0 gccaggcttc aagctgacct tttgttgccc cactcaaatc agcggtggcg ataatgagct 8328 0 gctcacgcac aaactgtaaa tagtggttat tcatgcgcac tccagttctg tgatttttat 8334 0 ccccagccgc tcaccaggaa cgagctgacc gcgcacaata ttgatttcat caaactgctc 8340 0 gtcgtctatg agaagtccgg catgcgtcag cacatccagt ggtgctttca ggatattgtc 8346 0 caggtcacga cggcgcttat ccggtggctc tgcaataatc tttatcacca gccttccgga 8352 0 caggtttaat ttcagccgct gctggcgaac aataagtgcc acatcccggc gataacgctc 8358 0 accggctttt gatacaaaat atgtgctgcc acgacgtcgc cagtaggtgt tcaccgtcgg 8364 0 cgggtaaggc aaaacaaact ctatacgcat cagtaacctc ttttacccga gcacgccggt 8370 0 tgcaaaggcg tgatcaagaa aacgaaaaat taaatcaacc tgggaaccat gcttttcttc 8376 0 gaacgccagc ggatccgcat gaagctcgtt gtgatgctcc cgacacagcg gtagcgtgaa 8382 0 aatatcgtgg gattttgttc ccattccgcc ctgaccatga ccaatcagat gatgaggatc 8388 0 gtccgctggc ttaccacaac acgcacacgg ctgtgtcttt acccagcgtg tgtatttctc 8394 0 atttacccag cggcgacgtt taggtcgttt catgaaggat tccggagact ccggatcaac 8400 0 ggcaatgctg accaccgtct tttcctgtgg tgggttctgt tgctggtggg tgtgaggcgg 8406 0 tagcgcaata ttttttgtgc gctgcttcag tatgctggtg gcggtctgtt ctcccggtat 8412 0 gatgtcgctt tcacggtata cggagcggat tttttccgca cgcaacccca gcgaacgacg 8418 0 taataccgct tccggtagcg cgtccgccac ctgattgcgg accgcccacc aggataattc 8424 0 agccagagat aattcacgct cctgtgcgcc attcattgcg tgacggatga tgtcaatcat 8430 0 ccaggcggcc agattctgtt gagcaagttg atccagtgaa tcagatgtct gctcccgcag 8436 0 ctggttgtcg cagtgccagc acaacaccat cgcgccggta ccgtaacggt gaatgacggt 8442 0 ttcgctgtga tgataatcac cgtgtagcca ctggcaggat ttcacgtgac gtaataacca 8448 0 gtcagacagt gcaccagcgc cacccgcagc acggatcacc cgctcatcgc tgaaaaatgg 8454 0 cagtagtgat ttatcttccg ccagcggctg gtgaacggca ggtacaaccc cggacggcag 8460 0 agctcgcatg ctttttggtt ccggctccac cagtattctg ccgttatgga atgctgacat 8466 0 tgattcacgg cctggcttaa cgataaccag accgagttcc ggtaccagaa caggtcgaag 8472 0 taatacccgc acattacctc cagatccgtt gctggaatgt gcgggacgga cgcggtggcc 8478 0 gttcggagta agggagcctg acggagatta tccagtgacg gtagtcgagg ctaagggctt 8484 0 ttttaacctc gcatccgcgc ctgcggtaac actgaatgag ccattcggcc tgttcttcag 8490 0 tgcatggggg atgctggtac cagtcagatt tgaatgcgta aaaacaccgt ccgcgcctgc 8496 0 tggcaaagac ggcagaatca tcagaattgt ataatttggt atcgtgcgcc atcggttgtc 8502 0 tctgctggcg cagcaggtgc cagttgttca ggctggcgtg cgaattgtaa accagaatgc 8508 0 caggaaaaaa caaaacccgc cgaagcgggt taagtgcggg tgcgttgagg atgcctgatt 8514 0 catcagaggt ggcgagggat ttctccctcg ccgggtctct tactcctcag gttcgtaagc 8520 0 tgtgaagaca gcgacctccg tctggccggt tcggattcgt acctcgcaga ggtctttcct 8526 0 cgttaccagt gccgtcacta tgacggtaat acagatgacg atcagggcga ttaacatcgc 8532 0 cttttgctgc ttcatagcct gcttctcctt gcctttcggc gcgtaagagg ctaacctaca 8538 0 tgtgtctagc atgaaattgg cctcagatta atgttaggcg tcttgcagga cgcgtaatgt 8544 0 taactggggc ttttctctgt ctgccttacg gtggcatgcc cgaggcagac agcctcaagc 8550 0 acccgcagca attctactta actctcgctt taccgcaaac cgtttttacc cgatatggga 8556 0 attcccatat cgtaatgaat tcagttccct agtcgatcca tcaaaaacac aaccaggcag 8562 0 taaacgccca caacagcaat aacagccagc gcaccttcca ttgccagtga aatatcatcc 8568 0 gacatattcc ctcctttggt gtgaatcccg gcgaacgttt ttacccccac cgacaaataa 8574 0 catatactaa aaaatcaata gctatagcaa cgcctgtaat tgcaaaggct tcaggccaga 8580 0 tcattggcgc acctcctgcg gcggttctgg tagcggcatc cagtcggtta cattgcggct 8586 0 ctgtgtttcg aaaaattcat caccattacg gactacatca aaaaactcac cgtctcgata 8592 0 ttgcgcataa agaacgaatg cgccatcaca taaaataatt acgtgctgac catcatccgg 8598 0 cattcgctca ctacagctta tccaatcatc cagagttacc ggatagttgg ttgacgtttc 8604 0 cgagatttcc cgaaaattat tggttgacga accctttttt tcccgaaagt ttccagcctg 8610 0 aagcatggcg gcgctgtctg gcggggcagc atatagcggc acgtatattt ccggttcctt 8616 0 atcagcaccg ggttgctctt ccagtgagaa tgtctttccg gtaaatcgat tcatataaag 8622 0 cacgggctct gcttccagcg aagcctgagc aacaagggcc agtgctaaat ccaactcaat 8628 0 tgcctcgaga gaatttttga atgctgtctg ttttactgca aatttcatcg cctttacatt 8634 0 ttcactaaca tgactgatta actgctcttt tgtaaaagtg gtcatctcat tctcctttga 8640 0 tgcgaatgcc agcgacaatt gaagcctgat agctaattca ctcacagtac cgcctcctga 8646 0 aaattgccct gatagaacgc cagtacacgc agcataactt cactcttccg gcactcgcca 8652 0 cagattatgt tctgttgtct gtcgtagcgg cgtatttctc cgtctggtaa ctttcgaatc 8658 0 aatgtctggt cggttgcttt ctccgctgcc ttacgccata cgcgatacac ctgttctgat 8664 0 gtaaaaacac cgtatttacc gggcatgtat aaatcgccac aagccagtac atccacaagg 8670 0 caacgtctga ctgaatgcca gcctgctccc gtcgctctct ccagttgtga tatcgtcatg 8676 0 cgttcatttt tgcgtaccag cccgataatt cgggccttca gttcttcacg ctgttcgtgt 8682 0 gtaaaaggtt tcgccataag cgcctccggc tatcactttt ccgatacaac acggcgggaa 8688 0 gaatcagtaa tctgtcgaac aatatcccgg tgcttgttca gctcccgcag cgcggcgcag 8694 0 actcgctccc acttctgaac atcacttttc gccctgcgca gcgccaggtt tgccctgcgc 8700 0 agggacggaa aaatcagctc atctgcttgc gtttcggtaa acgatggcaa cggctgcaca 8706 0 atgtccgcca cagtttctgt tttaatttct tcctgtgttg cggcttcccg gactggtaac 8712 0 gcagcacctg ctggctgagg aaaggcctta ccatcatttt tcgttaccgg cgcggctttc 8718 0 ggatctgctg gtaaattacc ccccgacatg cagtaacgaa atttaccgtt ctgattaacg 8724 0 cgtgccagcc gccccgttgc ggttaccacc gccagcgtgg aagcaacctt gcgagtactg 8730 0 acgccgaact tacccgccag ttcctcacac gttttagcac catcctgacc gataaactca 8736 0 accatcatgt ctgcggtaac ttttggagcg acctcttcgg ttaccacatc cggcgcttca 8742 0 ggttgtagtg cctgcccttc ggttaccccg gcttcacctt cgacagccag aaaccaggtg 8748 0 tgacccgttt tatcaacaac gccatttttt tgagttccca cagttcgtta agaacttctt 8754 0 cacggctgat atcaagccgc gccgccagtt caacagaatt ggcttttccc atcgctttca 8760 0 gtgcatgcaa tacagtttcc atcgaaaatt tacctcgtca aaaattctca cataccctga 8766 0 cgtccaacgt ttgaccgcca gctctcccag ttaaaattca cccaacgacc accattcatg 8772 0 gtcatacggt ccatcacccg atctccgagg agtgtgctca tcgctgcgtg attcaggttc 8778 0 gtcagcattc cgacactacg catcgaagcc gttctgcggt cgactatctg gttcagcgtg 8784 0 acctgctcgt tgcgcgtatc ccgctgcatg ccaatttcat caaggaccag aaggtcaact 8790 0 ccacaaagct cctgtaaaaa tttttccccg gactggccgt tgtcgtagcc gtcatgcaac 8796 0 acgctcatga catcggacac ggtgacgata atcacgcttc tccccttcgc catcagccga 8802 0 ttgccaatcg ctgctgccag gtgattttta ccggtaccag gtttaccgct gaacacgaag 8808 0 tttgtacatc cggtcatcaa ttcatcggca atggatttcg cctggctcag agcatggcgc 8814 0 tgaccgtcgt tctgcacccg gtagttcccg aatgagcact tcctgtgaag cggctggatg 8820 0 cccgcacggt tcaggatttt ttcaacccgc acctgatgat tcaggcggtt aatctcctcg 8826 0 ctgcgttttc gtccttcagc aagttgccat tcccgccact cctccaccgt ccggtacggt 8832 0 ggaaccgccc cctgtggtgc aagtctgcga atacgttcaa gaaccccaac tgccgcaatg 8838 0 tttttcatga cacgtcaccc cctgaatccc ggcggtattt cagtgtccgg ttcagaaatg 8844 0 tgattcacgc aacgctgcgc gggcgaacgc cccaggcgga taaccagttc atcccatttt 8850 0 tcccggagtt ttgccggact catgatgttt tttacccaga acgaatcccg ctggagacgc 8856 0 ccaaacattt cacaaatttg tctgtgagtt ctgccatcca gcatccgcat tgtccgcacg 8862 0 tcattggccc atgcagtcca gttgggttct ttcggtctcg tgatctcgcc atcatcgctg 8868 0 gccgcctgct cgtaaagact cacgattcgt ccccagatcc actgtgcgca caccaaatct 8874 0 tcctgacttc cccactggcg ttttttcgca ctgaacacaa ccgcgtcagg gtgtcgggtt 8880 0 aaaaaattct gttcagccgt ctgcgggtcc ggttgcgaag cgtccggaca agaagatctt 8886 0 ttatctgacg gatcaggttt taatactgac ggatcggggt caatcatcgc ccccctaatc 8892 0 ggcagtttgt tatcaacagt tgatccatca aaatttgacg ggtcaaccgt tgagggggca 8898 0 atatttgacg ggtcaactgt taacgggtca ttttttgccg ggctaatttt tcttttcggt 8904 0 ttatatgact cacgcgccgc cgcagcagct gcttcgagtt tttccacatt aagccgatag 8910 0 atattgctta cattacgccc accgacctta cgctcttcct tcgtcagcca gccctctttc 8916 0 gccagttctg caatagccga tttcactgtg gattcacttc ttgcaccgat ctgacgccgg 8922 0 atagtttcaa tggcaggcca tgacacgccc tcgtcattgc tgtagtctgc aagacgggcc 8928 0 ataaccgcca ccctggataa gatcatgccg gtgaaggcgc acccttccca gacaagacca 8934 0 tgaagcttgc tgctcataaa acccccgaac accgtgcttt tagtgcatca ccacagcatt 8940 0 ccctgccggg ccgccgcgat tcatctggtc atacaaaaca accgctgacg caacaaaatc 8946 0 atcgacatcc ttcaccagcc gatccctccg ttcgacgatc tcacggtaat attcagaact 8952 0 gtggctgcgc atacgggcca ccagcaaagg cggcatcgcc ttttcgatcg ccggtaacag 8958 0 agcctgcatt ttttcaacag catcaggggt gtctttatcc agccaacgga aaattttctg 8964 0 ggtattacgg gccagggctt ccggatggct gtcgtcatac agttccggga acgtcattcc 8970 0 cagctcgaaa tacgctttgg taattttcgc agccggtact ttttcgccgt ccggatgcgc 8976 0 ccagacattc atcgccatgc ggatgtgttc atgcttgatt ttcatgaatc aactccatca 8982 0 gataagcatg cactacaatc accttcagca tgaactacat gtgtttgccc caaacgaatg 8988 0 ccgctcgcat actcaggcca aataagctcc caatcatggg gtcgtagctc cgccctactt 8994 0 acttggcctt ccgtcgcaga ttcgatcata agggcgcggg ttggagatat agctgttcgt 9000 0 ccagacgcca tttgcgataa gtaagatggc gatacaccaa gtctggccgc gaatttctta 9006 0 gcatcaccaa cccttaatga tttaataaac tcttttaatg tcataccttc ctcggtttag 9012 0 tgtttttttg cgagtttagt gtttaataaa ccattaagtc aagtatttgc ttgtttagtg 9018 0 attactaaag ataattacca catgcaaaaa aaagaaattc gccgtttacg tctcaaggag 9024 0 tggtttaaag ataaaactct gccacccaaa gagaagagct acctatctca actaatgagt 9030 0 gggagagcct cgtttggaga aaaggctgcc agaagaatag agcaaacata cgggatgccg 9036 0 gaagggtatc tggatgcgga atacgcagaa caaccggggg gttctccacc acatgcaggg 9042 0 ttaacgtcta atcaactgga attattgcag attttttcag ccttccctga ggatgagcaa 9048 0 cgccagataa tcagcgagtt aaagcagaaa aaagaatcaa tggaagatct catagcgaga 9054 0 tggattgcgg cgcaaaaatg ccgccgcgcc tgagttataa aaccggagga aacatgaata 9060 0 gagccctttc accaatggtt tctgaatttg aaaccattga acaagaaaac agttacaacg 9066 0 aatggctgcg tgcgaaagta gcaacgagcc ttgcagatcc gcgcccagca attccccatg 9072 0 acgaagttga gcgcagaatg gcagaacgct ttgctaagat gcgcaaggaa cggagcaagc 9078 0 agtaaaatgt tacccgtgtt atggcttgaa agcgcagata ccgacctaga tgatataact 9084 0 agttatattg ctcgtttcga catagatgcg gctgaacgct tatggcagcg attaaggggt 9090 0 tgtgtgctgc cgttatccga acatccgtat ttatacccac caagcgacag agtacctggc 9096 0 ttgcgtgaga ttgtagccca ccctaactat ataattctat accgcgtaac aacatcaagc 9102 0 gttgaagtag taaacgtgat ccacgcaaga cgccagtttc cctaactttc actaccaata 9108 0 gaaacataac aaccgcaacg actttatcaa aagcgttgtg tttgttatgt cccgcggttt 9114 0 agtttttact tgacttaagt ttaatgttta ttaaactaaa aataccaacc caccccgccc 9120 0 cacagaacgc agggaaatac ttcgagttac ccggcagtgg tcaggggtta agtagccagc 9126 0 ccgaggcgta tgaacatgac ggcagggttc aactttaata actatgcagc agttttttgt 9132 0 tccgctaccc cggcgttaag gggaaacaga gggtttctca gtgggcgaag tcaaacatca 9138 0 gaatggaagg catcccggga tcggcaaaga agcagcaatg gcgctttata ttgacatcag 9144 0 cgccattgca ggacaggtaa gagttatcag agcggtaact aagcggtatg cgcctttact 9150 0 tcagaaagtc tctggtgagt gcaccgaaga tattgtcaac gatttcgtca tcgaactgcg 9156 0 aggactcatc ttcagttaca aggtgaccac aatttttgca gatggctccc gcgaaactgt 9162 0 cagagccctg cggcttaaag gatgtgtcaa agacttagcc accacattct gggcaagaaa 9168 0 acttgattgt attcataacc aatttcctct cgagtaacag acccctcaga ggataccacc 9174 0 tcgcctgacg tggttaaaag caggcaacgc ta ９１
７７ ２ ＜２１０＞ ２ ＜２１１＞ ２１４ ＜２１２＞ ＰＲＴ ＜２１３＞ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ Ｏ１５７：Ｈ７ ＜２２１＞ ＣＤＳ ＜２２２＞ ｃｏｍｐｌｅｍｅｎｔ（３９７．．１０３８） ＜４００＞ ２ Ｍｅｔ Ｐｒｏ Ｖａｌ Ａｓｐ Ｌｅｕ Ｔｈｒ Ｐｒｏ Ｔｙｒ Ｉｌｅ
Ｌｅｕ Ｐｒｏ Ｇｌｙ Ｖａｌ Ｓｅｒ Ｐｈｅ Ｌｅｕ １ ５
１０ １５ Ｓｅｒ Ａｓｐ Ｉｌｅ Ｐｒｏ Ｇｌｎ Ｇｌｕ Ｔｈｒ Ｌｅｕ Ｓｅｒ
Ｇｌｕ Ｉｌｅ Ａｒｇ Ａｓｎ Ｇｌｎ Ｔｈｒ Ｉｌｅ ２０ ２５
３０ Ａｒｇ Ｇｌｙ Ｇｌｕ Ａｌａ Ｇｌｎ Ｖａｌ Ａｒｇ Ｌｅｕ Ｇｌｙ
Ｇｌｕ Ｌｅｕ Ｍｅｔ Ｖａｌ Ｓｅｒ Ｉｌｅ Ａｒｇ ３５ ４０
４５ Ｐｒｏ Ｍｅｔ Ｇｌｎ Ｖａｌ Ａｓｎ Ｇｌｙ Ｔｙｒ Ｐｈｅ Ｍｅｔ
Ｇｌｙ Ｓｅｒ Ｌｅｕ Ａｓｎ Ｇｌｎ Ａｓｐ Ｇｌｙ ５０ ５５
６０ Ｌｅｕ Ｓｅｒ Ａｓｎ Ａｓｐ Ａｓｎ Ｉｌｅ Ｇｌｎ Ｉｌｅ Ｇｌｙ
Ｌｅｕ Ｇｌｎ Ｔｙｒ Ｉｌｅ Ｇｌｕ Ｈｉｓ Ｉｌｅ ６５ ７０
７５ ８０ 85 90 95 Leu Arg Glu Ile Glu Met Leu Glu Asn Met Glu Leu Leu Ser Asn Tyr 100 105 110 Gln Leu Glu Glu Leu Leu Asp Lys Ile Glu Val Cys Ala Phe Asn Val 115 120 125 Glu His Ala Gln Leu Gln Val Pro Glu Ser Leu Arg Thr Cys Pro Val 130 135 140 Thr Leu Cys Glu Pro Glu Asp Gly Val Phe Met Arg Asn Ser Met Asn 145 150 155 160 Ser Asn Val Cys Met Leu Tyr Asp Lys Met Ser Leu Ile Tyr Leu Val 165 170 175 Lys Thr Arg Ala Ala His Pro Leu Ser Arg Glu Ser Ile Ala Val Ser 180 185 190 Met Ile Val Gly Arg Asp Asn Cys Ala Phe Asp Ser Asp Arg Gly Asn 195 200 205 Phe Val Leu Lys Asn * 210 <210> 3 <211> 210 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1120..1749) <400> 3 Met Pro Val Thr Thr Leu Ser Ile Pro Ser Ile Ser Gln Leu Ser Pro 1 5 10 15 Ala Arg Val Gln Ser Leu Gln Asp Ala Ala Arg Leu Glu Ser Gly Ile 20 25 30 Arg Ile Ser Ile Gly Ser Gly Gln Tyr Ser Val His Tyr Val Gln Leu 35 40 45 Leu Asp Gly Phe Ser Val Glu Pro Val Arg Gly Gly Leu Leu Asp Arg 50 55 60 Leu Leu Gly Arg Glu His Arg Met Asp Arg Arg Ala Val Ala Leu Glu 65 70 75 80 Arg Gln Leu Asn Gly Gly Val Asp Phe Leu Ser Ser Val Asn Asn Tyr 85 90 95 Phe Gln Ser Val Met Ala Glu His Arg Glu Asn Lys Thr Gly Asn Lys 100 105 110 Ile Leu Met Glu Lys Ile Asn Ser Cys Val Phe Gly Thr Asp Ser Asn 115 120 125 His Phe Ser Cys Pro Glu Ser Phe Leu Thr Cys Pro Ile Thr Leu Asp 130 135 140 Thr Pro Glu Thr Gly Val Phe Met Arg Asn Ser Arg Gly Ala Glu Ile 145 150 155 160 Cys Ser Leu Tyr Asp Lys Asp Ala Leu Val Gln Leu Val Glu Thr Gly 165 170 175 Gly Thr His Pro Leu Ser Arg Glu Pro Ile Thr Glu Ser Met Ile Met 180 185 190 Arg Lys Asp Glu Cys His Phe Asp Ala Lys Arg Glu Ala Phe Cys Cys 195 200 205 Lys * <210> 4 <211> 192 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1822..2397) <400> 4 Met Pro Leu Thr Ser Asp Ile Arg Ser His Ser Phe Asn Leu Gly Val 1 5 10 15 Glu Val Val Arg Ala Arg Ile Val Ala Asn Gly Arg Gly Asp Ile Thr 20 25 30 Val Gly Gly Glu Thr Val Ser Ile Val Tyr Asp Ser Thr Asn Gly Arg 35 40 45 Phe Ser Ser Ser Gly Gly Asn Gly Gly Leu Leu Ser Glu Leu Leu Leu 50 55 60 Leu Gly Phe Asn Ser Gly Pro Arg Ala Leu Gly Glu Arg Met Leu Ser 65 70 75 80 Met Leu Ser Asp Ser Gly Glu Ala Gln Ser Gln Glu Ser Ile Gln Asn 85 90 95 Lys Ile Ser Gln Cys Lys Phe Ser Val Cys Pro Glu Arg Leu Gln Cys 100 105 110 Pro Leu Glu Ala Ile Gln Cys Pro Ile Thr Leu Glu Gln Pro Glu Lys 115 120 125 Gly Ile Phe Val Lys Asn Ser Asp Gly Ser Asp Val Cys Thr Leu Phe 130 135 140 Asp Ala Ala Ala Phe Ser Arg Leu Val Gly Glu Gly Leu Pro His Pro 145 150 155 160 Leu Thr Arg Glu Pro Ile Thr Ala Ser Ile Ile Val Lys His Glu Glu 165 170 175 Cys Ile Tyr Asp Asp Thr Arg Gly Asn Phe Ile Ile Lys Gly Asn * 180 185 190 <210> 5 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2511..2780) <400> 5 Met Asn Ile Leu Lys Lys Ile Met Gln Arg Leu Cys Gly Cys Gly Lys 1 5 10 15 His Asp Asp Arg Glu Asn Gly Glu Leu Leu Thr Ala Gln Leu Arg Leu 20 25 30 Gly Pro Ala Asp Ile Leu Glu Ser Asp Glu Asn Gly Ile Ile Pro Glu 35 40 45 Gln Asp Arg Val Ile Thr Gln Val Val Ile Leu Asp Ala Asp Lys Lys 50 55 60 Gln Ile Gln Cys Val Val Arg Pro Leu Gln Ile Leu Arg Ala Asp Gly 65 70 75 80 Thr Trp Glu Asn Ile Gly Gly Met Lys * 85 <210> 6 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2782..3060) <400> 6 Val Gly Ala Thr Gly Pro Gln Gly Pro Lys Gly Asp Pro Gly Glu Thr 1 5 10 15 Gln Ile Arg Phe Arg Leu Gly Pro Gly Asn Ile Ile Glu Thr Asn Ser 20 25 30 His Gly Trp Phe Pro Asp Thr Asp Gly Ala Leu Ile Thr Gly Leu Thr 35 40 45 Phe Leu Asp Pro Lys Asp Ala Thr Arg Val Gln Gly Phe Phe Gln His 50 55 60 Leu Gln Val Arg Phe Gly Asp Gly Pro Trp Gln Asp Val Lys Gly Leu 65 70 75 80 Asp Glu Val Gly Ser Asp Thr Gly Arg Thr Gly Glu * 85 90 <210> 7 <211> 272 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3194..4009) <400> 7 Val Asn Met Ala Val Lys Ile Ser Gly Val Leu Lys Asp Gly Thr Gly 1 5 10 15 Lys Pro Val Glu Asn Cys Thr Ile Gln Leu Lys Ala Arg Arg Asn Ser 20 25 30 Ala Thr Val Val Val Asn Thr Val Ala Ser Glu Asn Pro Asp Glu Ala 35 40 45 Gly Arg Tyr Ser Met Asp Val Glu Tyr Gly Gln Tyr Ser Val Ile Leu 50 55 60 Leu Val Glu Gly Phe Pro Pro Ser His Ala Gly Thr Ile Thr Val Tyr 65 70 75 80 Glu Asp Ser Gln Pro Gly Thr Leu Asn Asp Phe Leu Gly Ala Met Ser 85 90 95 Glu Asp Asp Val Arg Pro Glu Ala Leu Arg Arg Phe Glu Leu Met Val 100 105 110 Glu Glu Ala Ala Arg His Ala Glu Glu Ala Lys Lys Asn Ala Gly Glu 115 120 125 Ala Glu Thr Ser Ala Arg Asn Ala Gly Ile Ser Ala Ser Gln Ala Glu 130 135 140 Glu Ser Ala Ala Asn Ala Asp Thr Ser Ala Gly Asp Ala Ser Glu Ser 145 150 155 160 Ala Arg Gln Ala Ala Glu Ser Ala Ala Ala Ala Lys Gln Ser Glu Glu 165 170 175 Ala Ser Ser Ser Ser Ala Ser Ala Ala Ala Gln Lys Ala Ser Glu Ser 180 185 190 Ser Gln Ser Ala Ala Asp Ala Glu Leu Ser Lys Lys Thr Ala Glu Ser 195 200 205 Ala Ala Gly Asn Ala Ala Arg Met Gln Arg Pro Gln Gln Lys Lys Pro 210 215 220 Gly Ser Gln Gln Lys Ala His Ser Gln Arg Glu Gln Ser Arg Ile Ala 225 230 235 240 Ala Glu Glu Ala Val Asn Arg Ile Pro Thr Val Val Gly Leu Pro Ala 245 250 255 Lys Gly Gly Thr Gly Ser Arg Gly Ser Ser Gly Ala Glu Gly Arg * 260 265 270 <210> 8 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4068..4667) <400> 8 Met Arg Lys Leu Tyr Ala Ala Ile Leu Ser Ala Ala Ile Cys Leu Ala 1 5 10 15 Val Ser Gly Ala Pro Ala Trp Ala Ser Glu Gln Gln Ala Thr Leu Ser 20 25 30 Ala Gly Tyr Leu His Ala Arg Thr Ser Ala Pro Gly Ser Asp Asn Leu 35 40 45 Asn Gly Ile Asn Val Lys Tyr Arg Tyr Glu Phe Thr Asp Thr Leu Gly 50 55 60 Leu Val Thr Ser Phe Ser Tyr Ala Gly Asp Lys Asn Arg Gln Leu Thr 65 70 75 80 Arg Tyr Ser Asp Thr Arg Trp His Glu Asp Ser Val Arg Asn Arg Trp 85 90 95 Phe Ser Val Met Ala Gly Pro Ser Val Arg Val Asn Glu Trp Phe Ser 100 105 110 Ala Tyr Ala Met Ala Gly Val Ala Tyr Ser Arg Val Ser Thr Phe Ser 115 120 125 Gly Asp Tyr Leu Arg Val Thr Asp Asn Lys Gly Lys Thr His Asp Val 130 135 140 Leu Thr Gly Ser Asp Asp Gly Arg His Ser Asn Thr Ser Leu Ala Trp 145 150 155 160 Gly Ala Gly Val Gln Phe Asn Pro Thr Glu Ser Val Ala Ile Asp Ile 165 170 175 Ala Tyr Glu Gly Ser Gly Ser Gly Asp Trp Arg Thr Asp Gly Phe Ile 180 185 190 Val Gly Val Gly Tyr Lys Phe * 195 <210> 9 <211> 1160 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4735..8214) <400> 9 Val Gly Lys Gly Gly Gly Lys Gly His Thr Pro Val Glu Ala Lys Asp 1 5 10 15 Asn Leu Lys Ser Thr Gln Met Met Ser Val Ile Asp Ala Ile Gly Glu 20 25 30 Gly Pro Ile Glu Gly Pro Val Lys Gly Leu Gln Ser Ile Leu Val Asn 35 40 45 Lys Thr Pro Leu Thr Asp Thr Asp Gly Asn Pro Val Ile His Gly Val 50 55 60 Thr Ala Val Trp Arg Ala Gly Glu Gln Glu Gln Thr Pro Pro Glu Gly 65 70 75 80 Phe Glu Ser Ser Gly Ala Glu Thr Ala Leu Gly Val Glu Val Thr Lys 85 90 95 Ala Lys Pro Val Thr Arg Thr Ile Thr Ser Ala Asn Ile Asp Arg Leu 100 105 110 Arg Val Thr Phe Gly Val Gln Ser Leu Leu Glu Thr Thr Ser Lys Gly 115 120 125 Asp Arg Asn His Ser Ser Val Arg Leu Leu Ile Gln Leu Gln Arg Asn 130 135 140 Gly Asn Trp Val Thr Glu Lys Asp Val Thr Ile Asn Gly Lys Thr Thr 145 150 155 160 Ser Gln Phe Leu Ala Ser Val Ile Leu Asp Asn Leu Pro Pro Arg Pro 165 170 175 Phe Asn Ile Arg Met Val Arg Glu Thr Ala Asp Ser Thr Thr Asp Gln 180 185 190 Leu Gln Asn Arg Thr Leu Trp Ser Ser Tyr Thr Glu Ile Ile Asp Val 195 200 205 Lys Gln Cys Tyr Pro Asn Thr Ala Ile Val Gly Leu Gln Val Asp Ala 210 215 220 Glu Gln Phe Gly Gly Gln Gln Met Thr Val Asn Tyr His Ile Arg Gly 225 230 235 240 Arg Ile Ile Gln Val Pro Ser Asn Tyr Asp Pro Glu Lys Arg Thr Tyr 245 250 255 Ser Gly Ile Trp Asp Gly Ser Leu Lys Pro Ala Tyr Ser Asn Asn Pro 260 265 270 Ala Trp Cys Leu Trp Asp Met Leu Thr His Pro Arg Tyr Gly Met Gly 275 280 285 Lys Arg Leu Gly Ala Ala Asp Val Asp Lys Trp Ala Leu Tyr Ala Ile 290 295 300 Ala Gln Tyr Cys Asp Gln Met Val Pro Asp Gly Phe Gly Gly Thr Glu 305 310 315 320 Pro Arg Met Thr Phe Asn Ala Tyr Leu Ser Gln Gln Arg Lys Ala Trp 325 330 335 Asp Val Leu Ser Asp Phe Cys Ser Ala Met Arg Cys Met Pro Val Trp 340 345 350 Asn Gly Gln Thr Leu Thr Phe Val Gln Asp Ser Pro Ser Asp Val Val 355 360 365 Trp Pro Tyr Thr Asn Ser Asp Val Val Val Asp Asp Asn Gly Val Gly 370 375 380 Phe Arg Tyr Ser Phe Ser Ala Leu Lys Asp Arg His Thr Ala Val Glu 385 390 395 400 Val Asn Tyr Thr Asp Pro Gln Asn Gly Trp Gln Thr Ser Thr Glu Leu 405 410 415 Val Glu Asp Pro Glu Ala Ile Leu Arg Tyr Gly Arg Asn Leu Leu Lys 420 425 430 Met Asp Ala Phe Gly Cys Thr Ser Arg Gly Gln Ala His Arg Ala Gly 435 440 445 Leu Trp Val Ile Lys Thr Gly Leu Leu Glu Thr Gln Thr Val Asp Phe 450 455 460 Thr Leu Gly Ser Gln Gly Leu Arg His Thr Pro Gly Asp Ile Ile Glu 465 470 475 480 Ile Cys Asp Asn Asp Tyr Ala Gly Thr Met Thr Gly Gly Arg Ile Leu 485 490 495 Ser Ile Asp Ala Ala Ser Arg Thr Leu Thr Leu Asp Arg Glu Val Thr 500 505 510 Leu Pro Glu Thr Gly Ala Ala Thr Val Asn Leu Ile Asn Gly Ser Gly 515 520 525 Lys Pro Val Ser Val Ala Ile Thr Ala His Pro Ala Pro Asp Arg Ile 530 535 540 Gln Val Ser Thr Leu Pro Asp Gly Val Glu Thr Tyr Gly Val Trp Gly 545 550 555 560 Leu Ser Leu Pro Ser Leu Arg Arg Arg Leu Phe Arg Cys Val Ser Ile 565 570 575 Arg Glu Asn Thr Asp Gly Thr Phe Ala Ile Thr Ala Val Gln His Val 580 585 590 Pro Glu Lys Glu Ala Ile Val Asp Asn Gly Ala His Phe Asp Gly Asp 595 600 605 Gln Ser Gly Thr Leu Asn Ser Val Ile Pro Pro Ala Val Gln His Leu 610 615 620 Thr Val Glu Val Ser Ala Ala Asp Ser Gln Tyr Leu Ala Gln Ala Lys 625 630 635 640 Trp Asp Thr Pro Arg Val Val Lys Gly Val Arg Phe Ser Leu Arg Leu 645 650 655 Thr Ser Gly Ser Gly Gln Asp Ser Arg Leu Val Thr Thr Ala Ile Thr 660 665 670 Ala Asp Thr Glu His Arg Phe Ser Gly Leu Pro Leu Gly Glu Tyr Thr 675 680 685 Leu Thr Val Arg Ala Ile Asn Ser Tyr Gly Gln Gln Gly Glu Pro Ala 690 695 700 Ile Thr Thr Phe Arg Ile Asn Ala Pro Ala Lys Pro Ala Thr Ile Glu 705 710 715 720 Leu Thr Pro Gly Tyr Phe Gln Ile Thr Ala Val Pro Val Leu Ala Val 725 730 735 Tyr Asp Pro Thr Val Gln Phe Glu Phe Trp Phe Ser Glu Lys Arg Ile 740 745 750 Thr Asn Thr Ala Gln Val Glu Lys Ser Ala Arg Tyr Leu Gly Ser Gly 755 760 765 Ser Gln Trp Thr Val Gln Gly Ser Arg Ile Lys Pro Gly Thr Asp Phe 770 775 780 Trp Phe Tyr Val Arg Ser Val Asn Leu Val Gly Lys Ser Ala Phe Val 785 790 795 800 Glu Val Ser Gly Gln Pro Ser Asn Asp Gly Glu Gly Tyr Leu Glu Phe 805 810 815 Phe Arg Glu Lys Ile Gly Lys Leu His Leu Ala Gln Gly Leu Trp Glu 820 825 830 Leu Ile Asp Asn Ser Gln Leu Ala Asp Glu Met Ala Glu Met Lys Thr 835 840 845 Thr Ile Thr Glu Thr Arg Asn Glu Ile Thr Gln Thr Val Ser Lys Thr 850 855 860 Leu Glu Asn Gln Ser Ala Thr Ile Gln Gln Ile Gln Arg Val Gln Lys 865 870 875 880 Asp Thr Asn Asp Asp Leu Ala Ala Leu Tyr Met Leu Lys Val Gln Lys 885 890 895 Thr Lys Asp Gly Ile Pro Tyr Val Ala Gly Ile Gly Ala Gly Ile Glu 900 905 910 Asp Thr Asp Gly Gln Pro Leu Ser Asn Ile Leu Leu Leu Ala Asp Arg 915 920 925 Ile Ala Met Ile Asn Pro Glu Ser Gly Asn Ser Thr Pro Leu Phe Val 930 935 940 Ala Gln Gly Asn Gln Leu Phe Met Asn Asp Val Phe Leu Lys Arg Leu 945 950 955 960 Phe Ala Val Ser Ile Thr Ser Ser Gly Asn Pro Pro Thr Phe Ser Leu 965 970 975 Thr Pro Asp Gly Arg Leu Thr Ala Lys Asn Ala Asp Ile Ser Gly Ser 980 985 990 Val Asn Ala Asn Ser Gly Thr Leu Asn Asn Val Thr Ile Asn Glu Asn 995 1000 1005 Cys Gln Ile Lys Gly Lys Leu Ser Ala Asn Gln Ile Glu Gly Asp Ile 1010 1015 1020 Val Lys Thr Val Ser Lys Ser Phe Pro Arg Thr Ser Thr Tyr Ala Ser 1025 1030 1035 1040 Gly Thr Ile Thr Val Arg Ile Ser Asp Asp Gln Lys Phe Asp Arg Gln 1045 1050 1055 Val Met Ile Pro Pro Val Leu Phe Arg Gly Gly Lys His Glu Asn Phe 1060 1065 1070 Asn Ser Asn Asn Gln Gln Ser Tyr Trp Tyr Ser Thr Cys Arg Leu Arg 1075 1080 1085 Val Thr Arg Asn Gly Gln Glu Ile Phe Asn Gln Ser Thr Thr Asp Ala 1090 1095 1100 Gln Gly Val Phe Ser Ser Val Ile Asp Met Pro Ala Gly Gln Gly Thr 1105 1110 1115 1120 Leu Thr Leu Thr Phe Thr Val Ser Ser Ser Gly Ala Asn Asn Trp Thr 1125 1130 1135 Pro Thr Thr Ser Ile Ser Asp Leu Leu Val Val Val Met Lys Lys Ser 1140 1145 1150 Thr Ala Gly Ile Ser Ile Ser * 1155 <210> 10 <211> 226 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8455..9132) <400> 10 Met Ala Thr Thr Asn Ala Phe Cys Leu Ala Ser Pro Pro Leu Ala Arg 1 5 10 15 Ile Cys Leu His Gly Asp Leu Gln Arg Phe Gly Arg Arg Leu Ser Leu 20 25 30 Tyr Val Asn Thr Ala Ala Glu Ala Ile Arg Ala Leu Ser Leu Gln Met 35 40 45 Pro Gly Phe Arg Arg Gln Met Asn Glu Gly Trp Tyr Gln Ile Arg Ile 50 55 60 Arg Gly Glu Asp Thr Ala Pro Glu Ala Val Tyr Ala Arg Leu His Glu 65 70 75 80 Pro Leu Gly Glu Gly Ala Val Ile His Ile Val Pro Arg Leu Ala Gly 85 90 95 Ala Gly Lys Gly Gly Leu Gln Ile Val Leu Gly Ala Ala Ala Ile Val 100 105 110 Gly Ser Phe Phe Thr Ala Gly Ala Thr Met Ala Leu Trp Gly Ala Ala 115 120 125 Leu Ser Ala Gly Gly Leu Thr Ala Thr Thr Met Leu Phe Ser Leu Gly 130 135 140 Ala Ser Met Ile Leu Gly Gly Val Ala Gln Met Leu Ala Pro Lys Ala 145 150 155 160 Lys Thr Pro Glu Tyr Arg Ala Thr Asp Asn Gly Lys Gln Asn Thr Tyr 165 170 175 Phe Ser Ser Leu Asp Asn Met Ile Ala Gln Gly Asn Pro Met Pro Val 180 185 190 Pro Tyr Gly Glu Met Leu Val Gly Ser Arg Arg Ile Ser Gln Asp Ile 195 200 205 Ser Thr Arg Asp Glu Gly Gly Asp Gly Lys Val Val Val Ile Gly Arg 210 215 220 Gly * 225 <210> 11 <211> 228 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9030..9713) <400> 11 Val Arg Leu Arg Asp Arg His Pro Gly Gly Arg Thr Val Pro Ala Leu 1 5 10 15 Arg Glu Tyr Leu Arg Arg Ala Gly Gly Val Phe Ser Tyr Cys Ala Gly 20 25 30 Arg Leu Ala Ala Gly Arg Asp Ala Gly Gly Asp Cys Gly Ala Gly Ser 35 40 45 Gln Pro Pro Gly Gly Leu Pro Trp Leu Ser Glu Ala Asp Arg Arg Leu 50 55 60 Gln Ile Lys Ser Ala Leu Pro Trp Trp Leu Val Cys Arg Gly Glu Ile 65 70 75 80 His Lys Phe Arg Cys Val Pro His Leu Thr Gly Arg Arg Phe Glu His 85 90 95 Gly Val Thr Asp Cys Tyr Thr Leu Phe Arg Asp Ala Tyr His Leu Ala 100 105 110 Gly Ile Thr Leu Pro Asp Phe Glu Arg Glu Asp Asp Trp Trp Arg Asn 115 120 125 Gly Gln Asn Leu Tyr Leu Asp Asn Met Ala Ala Thr Gly Phe Tyr Arg 130 135 140 Val Pro Leu Ser Ser Ala Gln Ala Gly Asp Ile Leu Leu Cys Cys Phe 145 150 155 160 Gly Ala Ser Val Ala Asn His Ala Ala Ile Tyr Cys Gly Asn Gly Glu 165 170 175 Leu Leu His His Leu Pro Glu Gln Leu Ser Lys Arg Glu Arg Tyr Ser 180 185 190 Glu Lys Trp Gln Arg Arg Thr His Ser Val Trp Arg His Arg His Trp 195 200 205 His Ala Ser Ala Phe Thr Gly Ile Cys Asn Asp Leu Ala Ala Ala Ser 210 215 220 Ala Cys Thr * 225 <210> 12 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9783..10481) <400> 12 Met Gln Asp Ile His Glu Glu Ser Leu Asn Glu Ser Val Lys Ser Glu 1 5 10 15 Gln Ser Pro Arg Val Val Leu Trp Glu Ile Asp Leu Thr Ala Gln Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Leu Asn Glu Lys Gly Glu Ala 35 40 45 Val Thr Trp Gln Gly Arg Gln Tyr Gln Ala Tyr Pro Ile Asp Gly Ser 50 55 60 Gly Phe Glu Met Asn Gly Lys Gly Ser Ser Ala Arg Pro Ser Leu Thr 65 70 75 80 Val Ser Asn Leu Phe Gly Leu Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Ala Thr Val Val Arg Arg Arg Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Ala Gly Asn Pro Glu Ala Asp Pro Glu 115 120 125 Gln Glu Leu Thr Asp Arg Trp Val Val Glu Gln Met Ser Ser Leu Thr 130 135 140 Ala Met Thr Ala Ser Phe Val Leu Ala Thr Pro Thr Glu Thr Asp Gly 145 150 155 160 Ala Leu Phe Pro Gly Arg Ile Met Leu Ala Asn Thr Cys Met Trp Asp 165 170 175 Tyr Arg Gly Asp Glu Cys Gly Tyr Asn Gly Pro Ala Val Ala Asp Glu 180 185 190 Phe Asp Asn Pro Thr Thr Asp Ile Arg Lys Asp Arg Cys Ser Lys Cys 195 200 205 Met Arg Gly Cys Glu Met Arg Gly Met Val Ala Asn Phe Gly Gly Phe 210 215 220 Leu Ser Ile Asn Lys Leu Ser Gln * 225 230 <210> 13 <211> 110 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10481..10810) <400> 13 Met Lys Thr Phe Arg Trp Lys Val Lys Pro Asp Met Glu Val Asn Ser 1 5 10 15 Gln Pro Ser Val Arg Glu Val Arg Phe Gly Asp Gly Tyr Ser Gln Arg 20 25 30 Met Ala Ala Gly Leu Asn Ala Asp Leu Lys Thr Tyr Arg Val Thr Leu 35 40 45 Ser Val Thr Arg Glu Glu Ala Arg His Leu Glu Ala Phe Leu Ala Glu 50 55 60 His Gly Gly Trp Lys Ala Phe Leu Trp Lys Pro Pro Tyr Ala Tyr Arg 65 70 75 80 Gln Ile Lys Val Thr Cys Ala Gly Trp Ser Ala Arg Val Gly Met Leu 85 90 95 Arg Val Glu Phe Ser Ala Glu Phe Lys Gln Val Val Asn * 100 105 <210> 14 <211> 871 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10807..13419) <400> 14 Met Ser Gln Pro Ala Gly Asp Leu Val Ile Asp Leu Ser Leu Asp Ala 1 5 10 15 Ala Arg Phe Asp Glu Gln Met Ala Arg Val Arg Arg His Phe Ser Ser 20 25 30 Leu Glu Ala Asp Ala Arg Lys Thr Ala Ser Thr Val Glu Gln Gly Leu 35 40 45 Ser Arg Gln Ala Leu Ala Ala Gln Lys Ala Gly Ile Ser Val Gly Gln 50 55 60 Tyr Lys Ala Ala Met Arg Thr Leu Pro Ala Gln Phe Thr Asp Ile Val 65 70 75 80 Thr Gln Leu Ala Gly Gly Gln Asn Pro Phe Leu Ile Met Leu Gln Gln 85 90 95 Gly Gly Gln Ile Ser Asp Ser Phe Gly Gly Pro Leu Ser Leu Leu Thr 100 105 110 Leu Leu Lys Glu Glu Leu Leu Gly Ile Arg Asp Ala Ser Glu Ser Ser 115 120 125 Glu Glu Ser Leu Ser Asp Thr Ala Asn Ala Leu Ala Glu Asn Ala Arg 130 135 140 Asn Ala Gly Glu Leu Gly Arg Phe Met Ser Val Ala Arg Val Ala Ala 145 150 155 160 Gly Gly Gly Val Ala Val Leu Ala Ala Leu Ala Ala Ala Ala Trp Gln 165 170 175 Ala Glu Gln Ala Asp Arg Ala Leu Leu Arg Ser Leu Ile Leu Thr Gly 180 185 190 Gly Ala Ala Ala Thr Thr Thr Ala Glu Leu Trp Lys Met Ala Gly Val 195 200 205 Ile Ser Asp Glu Ala Gly Gly Gly Ile Arg Gln Ala Ala Glu Asn Leu 210 215 220 Ala Arg Leu Ala Glu Ser Gly Lys Tyr Thr Ala Gly Gln Leu Arg Ile 225 230 235 240 Met Gly Glu Thr Ser Gln Arg Trp Leu Gln Thr Val Gly Asp Asp Ala 245 250 255 Gly Lys Val Glu Lys Ala Phe Glu Gly Ile Ala Ala Asp Pro Val Lys 260 265 270 Ala Leu Ala Ser Leu Asn Gln Gln Tyr Asn Phe Leu Ser Val Ser Gln 275 280 285 Leu Arg His Ile Asp Glu Leu Glu Arg Thr Lys Gly Lys Gln Val Ala 290 295 300 Val Thr Glu Ala Met Ser Leu Phe Ala Asp Val Met Asn Ala Arg Leu 305 310 315 320 Glu Gln Leu Asp Lys Ala Ala Thr Pro Val Glu Lys Ile Trp Asp Asp 325 330 335 Val Lys Thr Trp Thr Ser Asp Ala Trp Ala Trp Ile Gly Asp His Thr 340 345 350 Leu Gly Ala Leu Ser Leu Ile Thr Asp Val Val Ala Gly Thr Val Glu 355 360 365 Gln Val Lys Leu Leu Leu Val Gln Gly Asp Leu Ala Leu Ala Glu Phe 370 375 380 Ile Gln Ser Ala Trp Glu Thr Thr Lys Asn Val Pro Gly Val Gly Ala 385 390 395 400 Leu Phe Gly Glu Leu Ala Glu Glu Asn Arg Val Phe Ile Glu Lys Thr 405 410 415 Lys Arg Asp Glu Leu Ala Leu Arg Lys Ser Ile Ala Glu Arg Asp Ala 420 425 430 Arg Ile Arg Gln Gly Glu Met Gly Tyr Ile Asn Arg Ser Arg Ala Thr 435 440 445 Gly Val Ser Lys Gly Pro Gly Gln Gln Glu Ala Val Ser Arg Leu Ala 450 455 460 Glu Glu Leu Thr Gly Lys Lys His Thr Ser Pro Lys Thr Arg Ser Ala 465 470 475 480 Gly Glu Arg Glu Glu Glu Gln Ala Arg Glu Ala Leu Leu Ala Leu Glu 485 490 495 Ala Glu Leu Arg Thr Leu Glu Lys His Ser Gly Ala Asn Glu Lys Ile 500 505 510 Ser Arg Gln Arg Arg Asp Leu Trp Lys Ala Glu Ser Gln Tyr Ala Val 515 520 525 Leu Lys Glu Ala Ala Thr Lys Arg Gln Leu Ser Glu Gln Glu Lys Ser 530 535 540 Leu Leu Ala His Lys Asp Glu Thr Leu Glu Tyr Lys Arg Gln Leu Ala 545 550 555 560 Glu Leu Gly Asp Lys Val Glu Tyr Gln Lys Arg Leu Asn Glu Leu Ala 565 570 575 Gln Gln Ala Val Arg Phe Glu Glu Gln Gln Ser Ala Lys Gln Ala Ala 580 585 590 Ile Ser Ala Lys Ala Arg Gly Leu Thr Asp Arg Gln Ala Gln Arg Glu 595 600 605 Ser Glu Ala Gln Arg Leu Arg Asp Val Tyr Gly Asp Asn Pro Ala Ala 610 615 620 Leu Ala Lys Ala Thr Ser Ala Leu Lys Asn Thr Arg Ser Ala Glu Glu 625 630 635 640 Gln Leu Arg Gly Ser Trp Met Ala Gly Leu Lys Ser Gly Trp Gly Glu 645 650 655 Trp Ala Glu Ser Ala Thr Asp Ser Phe Ser Gln Val Lys Ser Ala Ala 660 665 670 Thr Gln Thr Phe Asp Gly Ile Ala Gln Asn Met Ala Ala Met Leu Thr 675 680 685 Gly Ala Glu Ala Asp Trp Arg Gly Phe Thr Arg Ser Val Leu Ser Met 690 695 700 Met Thr Glu Ile Leu Leu Lys Gln Ala Met Val Gly Ile Val Gly Arg 705 710 715 720 Ile Gly Ser Ala Ile Gly Gly Ala Phe Gly Gly Gly Ala Ser Ala Ser 725 730 735 Ser Gly Thr Ala Ile Gln Ala Ala Ala Ala Asn Phe His Phe Ala Thr 740 745 750 Gly Gly Phe Thr Gly Thr Gly Gly Lys Tyr Glu Pro Ala Gly Ile Val 755 760 765 His Arg Gly Glu Phe Val Phe Thr Lys Glu Ala Thr Ser Arg Ile Gly 770 775 780 Val Gly Asn Leu Tyr Arg Leu Met Arg Gly Tyr Ala Glu Gly Gly Tyr 785 790 795 800 Val Gly Gly Ala Gly Ser Pro Ala Gln Met Arg Arg Ala Glu Gly Ile 805 810 815 Asn Phe Asn Gln Asn Asn His Val Val Ile Gln Asn Asp Gly Thr Asn 820 825 830 Gly Gln Ala Gly Pro Gln Leu Met Lys Ala Val Tyr Asp Met Ala Arg 835 840 845 Lys Gly Ala Gln Asp Glu Leu Arg Leu Gln Leu Arg Asp Gly Gly Met 850 855 860 Leu Ser Gly Ser Gly Arg * 865 870 <210> 15 <211> 138 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13400..13813) <400> 15 Met Gly Arg Pro Asp Trp Arg Ala Met Leu Ala Gly Met Thr Ser Thr 1 5 10 15 Glu Tyr Ala Asp Trp Arg Arg Phe Tyr Cys Thr His Tyr Phe Gln Asp 20 25 30 Thr Gln Leu Asp Ala His Phe Ser Gly Leu Met Tyr Ala Val Leu Ser 35 40 45 Leu Phe Phe Gly Asp Pro Asp Met His Pro Ala Asp Phe Ser Leu Leu 50 55 60 Ala Pro Ala Cys Glu Glu Glu Gln Thr Glu Met Pro Asp Glu Glu Glu 65 70 75 80 Met Leu Met Gln Lys Ala Thr Gly Val Ala Gly Gly Val Arg Phe Gly 85 90 95 Gly Asp Gly Gly Arg Asp Ile Ser Pro Ser Ala Asp Val Val Asp Val 100 105 110 Ser Glu Asp Asp Val Ala Leu Met Met Ala Ser Ala Gly Ile Ser Gly 115 120 125 Gly Val Arg Tyr Val Pro Ala Ser Gly * 130 135 <210> 16 <211> 141 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13840..14262) <400> 16 Met Phe Leu Lys Thr Glu Gln Phe Glu Tyr Asn Gly Val Ser Val Thr 1 5 10 15 Leu Ser Glu Leu Ser Ala Leu Gln Arg Phe Asp Tyr Ile Lys Phe Val 20 25 30 Ser Asp Ala Glu Gln Gln Glu Thr Thr Lys His Asp Val Val His Ile 35 40 45 Asn Gln Arg Tyr Leu Glu Thr Ala Ser Leu Leu Val Ala Met Ser Leu 50 55 60 Trp His Ser His Ser Leu Lys Gly Thr Leu Ala Ser Pro Glu Thr Glu 65 70 75 80 Met Gln Gln Ile Arg Arg Glu Val Met Leu Gly Trp Pro Ala Asp Ala 85 90 95 Leu Asn Gln Ala Thr Asn Arg Val Leu Tyr Leu Ser Gly Met Leu Asp 100 105 110 Asn Arg His Asp Ala Asp Pro Glu Gln Thr Gly Lys Ala Glu Ala Thr 115 120 125 Glu Ser Val Thr Ser Lys Lys His Ser Lys Ala Ser * 130 135 140 <210> 17 <211> 251 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14276..15028) <400> 17 Met Ala Thr Pro Asn Pro Leu Glu Pro Val Lys Gly Ala Gly Thr Thr 1 5 10 15 Leu Trp Val Tyr Asn Gly Lys Gly Asp Ala Tyr Ala Asn Pro Leu Ser 20 25 30 Asp Asp Asp Trp Gln Arg Leu Ala Lys Val Lys Asp Leu Thr Pro Gly 35 40 45 Glu Met Thr Ala Glu Pro Tyr Asp Asp Asn Tyr Leu Asp Asp Glu Asp 50 55 60 Ala Asp Trp Thr Ala Thr Gly Gln Gly Gln Lys Ser Ala Gly Asp Thr 65 70 75 80 Ser Phe Thr Leu Ala Trp Lys Pro Gly Glu Glu Gly Gln Lys Gly Leu 85 90 95 Ile Gly Trp Phe Glu Ser Gly Asp Val Arg Ala Tyr Lys Ile Arg Phe 100 105 110 Pro Asn Gly Thr Val Asp Val Phe Arg Gly Trp Val Ser Ser Ile Gly 115 120 125 Lys Ala Val Thr Ala Lys Glu Val Ile Thr Arg Thr Val Lys Val Thr 130 135 140 Asn Val Gly Lys Pro Ser Val Ala Glu Glu Arg Ser Glu Ile Thr Pro 145 150 155 160 Ala Thr Ala Ile Lys Val Thr Pro Thr Ser Gly Thr Val Ala Lys Gly 165 170 175 Lys Thr Thr Thr Leu Thr Val Ser Phe Glu Pro Glu Ser Ala Thr Asp 180 185 190 Lys Thr Phe Arg Ala Val Ser Ala Asp Pro Ser Lys Ala Thr Ile Ser 195 200 205 Val Lys Asp Met Thr Ile Thr Val Asn Gly Val Ala Thr Gly Lys Val 210 215 220 Gln Ile Pro Val Val Ser Gly Asn Gly Gln Phe Ala Ala Val Ala Glu 225 230 235 240 Val Thr Val Thr Glu Ala Gly Ala Ala Gly * 245 250 <210> 18 <211> 132 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15036..15431) <400> 18 Met Lys His Thr Asp Ile Arg Ala Ala Val Leu Asp Ala Leu Glu Leu 1 5 10 15 His Glu His Gly Ala Thr Leu Phe Asp Gly Arg Pro Val Val Phe Asp 20 25 30 Glu Glu Asp Phe Pro Ala Val Ala Val Tyr Leu Thr Asp Ala Glu Tyr 35 40 45 Thr Gly Glu Glu Leu Asp Ala Asp Thr Trp Arg Ala Thr Leu His Ile 50 55 60 Glu Val Phe Leu Pro Ala Gln Val Pro Asp Ser Glu Leu Asp Gln Trp 65 70 75 80 Met Glu Ser Arg Ile Tyr Pro Ala Val Thr Ala Ile Pro Ala Leu Ala 85 90 95 Asp Leu Ile Thr Thr Met Val Thr Gln Gly Tyr Glu Tyr Arg Arg Asp 100 105 110 Asp Asp Met Ala Leu Trp Ser Ser Ala Asp Leu Thr Tyr Ser Ile Thr 115 120 125 Tyr Glu Met * 130 <210> 19 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15428..15961) <400> 19 Met Ala Ile Lys Gly Leu Asp Gln Ala Ile Glu Asn Leu Ser Arg Val 1 5 10 15 Arg Lys Asn Ala Ile Pro Ala Ala Ser Ala Met Ala Ile Asn Arg Val 20 25 30 Ala Thr Thr Ala Ile Asn Gln Ser Ser Ser Gln Val Ala Arg Glu Thr 35 40 45 Lys Val Arg Arg Lys Leu Val Lys Glu Arg Ser Arg Leu Lys Arg Ala 50 55 60 Thr Val Arg Asn Pro Asn Ala Arg Ile Ile Val Lys Arg Gly Asp Leu 65 70 75 80 Pro Val Ile Lys Leu Gly Ile Arg Met Leu Gly Arg Arg Pro Asp Ser 85 90 95 Ile Leu Lys Ala Gly Gln His Arg Tyr Gln Arg Ala Phe Ile Gln Arg 100 105 110 Leu Lys Asn Gly Arg Trp His Val Met Gln Arg Val Ala Gly Lys Asn 115 120 125 Arg Tyr Pro Ile Asp Val Val Lys Ile Pro Met Ala Ala Pro Leu Lys 130 135 140 Gln Ala Phe Asp Glu Asn Ile Asp Arg Ile Arg Arg Glu Arg Leu Pro 145 150 155 160 Gly Glu Leu Ala Tyr Ala Leu Lys Gln Gln Leu Arg Ile Ala Ile Lys 165 170 175 Arg * <210> 20 <211> 118 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15976..16329) <400> 20 Val Ala Asp Phe Asp Asn Leu Phe Asp Ala Ala Ile Ala Arg Ala Asp 1 5 10 15 Glu Thr Ile Arg Gly Tyr Met Gly Thr Ser Ala Thr Met Thr Ser Gly 20 25 30 Glu Arg Ser Gly Ala Val Ile Arg Gly Val Phe Asp Asp Pro Glu Asn 35 40 45 Ile Ser Tyr Ala Gly Gln Gly Val Arg Val Glu Gly Ser Ser Pro Ser 50 55 60 Leu Phe Val Arg Thr Asp Asp Val Arg Gln Leu Arg Arg Gly Asp Thr 65 70 75 80 Leu Thr Ile Asn Gly Glu Met Phe Trp Val Asp Arg Val Ser Pro Asp 85 90 95 Asp Gly Gly Ser Cys Tyr Leu Trp Leu Asn Arg Gly Gln Pro Pro Ala 100 105 110 Val Asn Arg Arg Arg * 115 <210> 21 <211> 133 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16341..16739) <400> 21 Met Thr Lys Asp Glu Leu Ile Ala Arg Leu Arg Ser Leu Gly Glu Gln 1 5 10 15 Leu Asn Arg Asp Val Ser Leu Thr Gly Thr Lys Glu Glu Leu Ala Leu 20 25 30 Arg Val Ala Glu Leu Glu Glu Glu Leu Asp Asp Thr Asp Glu Thr Ala 35 40 45 Gly Gln Asp Thr Pro Leu Ser Arg Glu Asn Val Leu Thr Gly His Glu 50 55 60 Asn Glu Val Gly Ser Ala Gln Pro Asp Thr Val Ile Leu Asp Thr Ser 65 70 75 80 Glu Leu Val Thr Val Val Ala Leu Val Lys Leu His Thr Asp Ala Leu 85 90 95 His Val Thr Arg Asp Glu Pro Val Ala Phe Val Leu Pro Gly Thr Ala 100 105 110 Phe Arg Val Ser Ala Gly Val Ala Ala Glu Met Thr Glu Arg Gly Leu 115 120 125 Ala Arg Met Gln * 130 <210> 22 <211> 342 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16781..17806) <400> 22 Met Ser Met Tyr Thr Thr Ala Gln Leu Leu Ala Ala Asn Glu Gln Lys 1 5 10 15 Phe Lys Phe Asp Pro Leu Phe Leu Arg Leu Phe Phe Arg Glu Ser Tyr 20 25 30 Pro Phe Thr Thr Glu Lys Val Tyr Leu Ser Gln Ile Pro Gly Leu Val 35 40 45 Asn Met Ala Leu Tyr Val Ser Pro Ile Val Ser Gly Glu Val Ile Arg 50 55 60 Ser Arg Gly Gly Ser Thr Ser Glu Phe Thr Pro Gly Tyr Val Lys Pro 65 70 75 80 Lys His Glu Val Asn Pro Gln Met Thr Leu Arg Arg Leu Pro Asp Glu 85 90 95 Asp Pro Gln Asn Leu Ala Asp Pro Ala Tyr Arg Arg Arg Arg Ile Ile 100 105 110 Met Gln Asn Met Arg Asp Glu Glu Leu Ala Ile Ala Gln Val Glu Glu 115 120 125 Met Gln Ala Val Ser Ala Val Leu Lys Gly Lys Tyr Thr Met Thr Gly 130 135 140 Glu Ala Phe Asp Pro Val Glu Val Asp Met Gly Arg Ser Ala Ala Asn 145 150 155 160 Asn Ile Thr Gln Ser Gly Gly Thr Glu Trp Ser Lys Arg Asp Lys Ser 165 170 175 Thr Tyr Asp Pro Thr Asp Asp Ile Glu Ala Tyr Ala Leu Asn Ala Ser 180 185 190 Gly Val Val Asn Ile Ile Val Phe Asp Pro Lys Gly Trp Ala Leu Phe 195 200 205 Arg Ser Phe Lys Ala Val Arg Glu Lys Leu Asp Thr Arg Arg Gly Ser 210 215 220 His Ser Glu Leu Glu Thr Ala Val Lys Asp Leu Gly Lys Ala Val Ser 225 230 235 240 Tyr Lys Gly Met Tyr Gly Asp Val Ala Ile Val Val Tyr Ser Gly Gln 245 250 255 Tyr Val Glu Asn Gly Val Lys Lys Asn Phe Leu Pro Asp Asn Thr Met 260 265 270 Val Leu Gly Asn Thr Gln Ala Arg Gly Leu Arg Thr Tyr Gly Cys Ile 275 280 285 Gln Asp Ala Asp Ala Gln Arg Glu Gly Ile Asn Ala Ser Ala Arg Tyr 290 295 300 Pro Lys Asn Trp Val Thr Thr Gly Asp Pro Ala Arg Glu Phe Thr Met 305 310 315 320 Ile Gln Ser Ala Pro Leu Met Leu Leu Ala Asp Pro Asp Glu Phe Val 325 330 335 Ser Val Gln Leu Ala * 340 <210> 23 <211> 111 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17862..18194) <400> 23 Met Thr Ser Lys Glu Thr Phe Thr His Tyr Gln Pro Leu Gly Asn Ser 1 5 10 15 Asp Pro Ala His Thr Ala Thr Ala Pro Gly Gly Leu Ser Ala Lys Ala 20 25 30 Pro Ala Met Thr Pro Leu Met Leu Asp Thr Ser Ser Arg Lys Leu Val 35 40 45 Ala Trp Asp Gly Thr Thr Asp Gly Ala Ala Val Gly Ile Leu Ala Val 50 55 60 Ala Ala Asp Gln Thr Ser Thr Thr Leu Thr Phe Tyr Lys Ser Gly Thr 65 70 75 80 Phe Arg Tyr Glu Asp Val Leu Trp Pro Glu Ala Ala Ser Asp Glu Thr 85 90 95 Lys Lys Arg Thr Ala Phe Ala Gly Thr Ala Ile Ser Ile Val * 100 105 110 <210> 24 <211> 440 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18204..19523) <400> 24 Val Thr Ala Glu Leu Arg Asn Leu Pro His Ile Ala Ser Met Ala Phe 1 5 10 15 Asn Glu Pro Leu Met Leu Glu Pro Ala Tyr Ala Arg Val Phe Phe Cys 20 25 30 Ala Leu Ala Gly Gln Leu Gly Ile Ser Arg Leu Thr Asp Ala Val Ser 35 40 45 Gly Asp Ser Leu Thr Ala Gly Glu Ala Pro Ala Ala Leu Ala Leu Ser 50 55 60 Gly Asp Asp Asp Gly Pro Arg Gln Ala Arg Ser Tyr Gln Val Met Asn 65 70 75 80 Gly Ile Ala Val Leu Pro Val Ser Gly Thr Leu Val Ser Arg Thr Arg 85 90 95 Ala Leu Gln Pro Tyr Ser Gly Met Thr Gly Tyr Asn Gly Ile Ile Ala 100 105 110 Arg Leu Gln Gln Ala Ala Ser Asp Pro Met Val Asp Gly Ile Leu Leu 115 120 125 Asp Met Asp Thr Pro Gly Gly Met Val Ala Gly Ala Phe Asp Cys Ala 130 135 140 Asp Ile Ile Ala Arg Val Arg Asp Ile Lys Pro Val Trp Ala Leu Ala 145 150 155 160 Asn Asp Met Asn Cys Ser Ala Gly Gln Leu Leu Ala Ser Ala Ala Ser 165 170 175 Arg Arg Leu Val Thr Gln Thr Ala Arg Thr Gly Ser Ile Gly Val Met 180 185 190 Met Ala His Ser Asn Tyr Gly Ala Ala Leu Glu Lys Gln Gly Val Glu 195 200 205 Ile Thr Leu Ile Tyr Ser Gly Ser His Lys Val Asp Gly Asn Pro Tyr 210 215 220 Ser His Leu Pro Gly Asp Val Arg Glu Thr Leu Gln Ser Arg Met Asp 225 230 235 240 Ala Thr Arg Arg Met Phe Ala Gln Lys Val Ser Ala Tyr Thr Gly Leu 245 250 255 Ser Val Gln Ala Val Leu Asp Thr Glu Ala Ala Val Tyr Ser Gly Gln 260 265 270 Glu Ala Ile Asp Ala Gly Leu Ala Asp Glu Leu Val Asn Ser Thr Asp 275 280 285 Ala Ile Thr Val Met Arg Asp Ala Leu Asp Ala Arg Lys Ser Arg Leu 290 295 300 Ser Gly Gly Arg Met Thr Lys Glu Thr Gln Ser Thr Thr Val Ser Ala 305 310 315 320 Thr Ala Ser Gln Ala Asp Val Thr Gly Val Val Pro Ala Thr Glu Gly 325 330 335 Glu Asn Ala Ser Ala Ala Gln Pro Asp Val Asn Ala Gln Ile Thr Ala 340 345 350 Ala Val Ala Ala Glu Asn Ser Arg Ile Met Gly Ile Leu Asn Cys Glu 355 360 365 Glu Ala His Gly Arg Glu Glu Gln Ala Arg Val Leu Ala Glu Thr Pro 370 375 380 Gly Met Thr Val Glu Thr Ala Arg Arg Ile Leu Ala Ala Ala Pro Gln 385 390 395 400 Ser Ala Gln Ala Arg Ser Asp Thr Ala Leu Asp Arg Leu Met Gln Gly 405 410 415 Ala Pro Ala Pro Leu Ala Ala Gly Asn Pro Ala Ser Asp Ala Val Asn 420 425 430 Asp Leu Leu Asn Thr Pro Val * 435 <210> 25 <211> 534 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19504..21105) <400> 25 Met Lys Met Ser Thr Ile Pro Thr Leu Leu Gly Pro Asp Gly Met Thr 1 5 10 15 Ser Leu Arg Glu Tyr Ala Gly Tyr His Gly Gly Gly Ser Gly Phe Gly 20 25 30 Gly Gln Leu Arg Ala Trp Asn Pro Pro Gly Glu Ser Val Asp Ala Ala 35 40 45 Leu Leu Pro Asn Phe Thr Arg Gly Asn Ala Arg Ala Asp Asp Leu Val 50 55 60 Arg Asn Asn Gly Tyr Ala Ala Asn Ala Ile Gln Leu His Gln Asp His 65 70 75 80 Ile Val Gly Ser Phe Phe Arg Leu Ser His Arg Pro Ser Trp Arg Tyr 85 90 95 Leu Gly Ile Gly Glu Glu Glu Ala Arg Ala Phe Ser Arg Glu Val Glu 100 105 110 Ala Ala Trp Lys Glu Phe Ala Glu Asp Asp Cys Cys Cys Ile Asp Val 115 120 125 Glu Arg Lys Arg Thr Phe Thr Met Met Ile Arg Glu Gly Val Ala Met 130 135 140 His Ala Phe Asn Gly Glu Leu Phe Val Gln Ala Thr Trp Asp Thr Arg 145 150 155 160 Pro Ser Arg Leu Phe Arg Thr Gln Phe Arg Met Val Ser Pro Lys Arg 165 170 175 Ile Ser Asn Pro Asn Asn Thr Ser Asp Ser Arg Asn Cys Arg Ala Gly 180 185 190 Val Gln Ile Asn Asp Ser Gly Ala Ala Leu Gly Tyr Tyr Val Ser Glu 195 200 205 Asp Gly Tyr Pro Gly Trp Met Pro Gln Lys Trp Thr Trp Ile Pro Arg 210 215 220 Glu Leu Pro Gly Gly Arg Ala Ser Phe Ile His Val Phe Glu Pro Val 225 230 235 240 Glu Asp Gly Gln Thr Arg Gly Ala Asn Val Phe Tyr Ser Val Met Glu 245 250 255 Gln Met Lys Met Leu Asp Thr Leu Gln Asn Thr Gln Leu Gln Ser Ala 260 265 270 Ile Val Lys Ala Met Tyr Ala Ala Thr Ile Glu Ser Glu Leu Asp Thr 275 280 285 Gln Ser Ala Met Asp Phe Ile Leu Gly Ala Asn Ser Gln Glu Gln Arg 290 295 300 Glu Arg Leu Thr Gly Trp Ile Gly Glu Ile Ala Ala Tyr Tyr Ala Ala 305 310 315 320 Ala Pro Val Arg Leu Gly Gly Ala Lys Val Pro His Leu Met Pro Gly 325 330 335 Asp Ser Leu Asn Leu Gln Thr Ala Gln Asp Thr Asp Asn Gly Tyr Ser 340 345 350 Val Phe Glu Gln Ser Leu Leu Arg Tyr Ile Ala Ala Gly Leu Gly Val 355 360 365 Ser Tyr Glu Gln Leu Ser Arg Asn Tyr Ala Gln Met Ser Tyr Ser Thr 370 375 380 Ala Arg Ala Ser Ala Asn Glu Ser Trp Ala Tyr Phe Met Gly Arg Arg 385 390 395 400 Lys Phe Val Ala Ser Arg Gln Ala Ser Gln Met Phe Leu Cys Trp Leu 405 410 415 Glu Glu Ala Ile Val Arg Arg Val Val Thr Leu Pro Ser Lys Ala Arg 420 425 430 Phe Ser Phe Gln Glu Ala Arg Ser Ala Trp Gly Asn Cys Asp Trp Ile 435 440 445 Gly Ser Gly Arg Met Ala Ile Asp Gly Leu Lys Glu Val Gln Glu Ala 450 455 460 Val Met Leu Ile Glu Ala Gly Leu Ser Thr Tyr Glu Lys Glu Cys Ala 465 470 475 480 Lys Arg Gly Asp Asp Tyr Gln Glu Ile Phe Ala Gln Gln Val Arg Glu 485 490 495 Thr Met Glu Arg Arg Ala Ala Gly Leu Lys Pro Pro Ala Trp Ala Ala 500 505 510 Ala Ala Phe Glu Ser Gly Leu Arg Gln Ser Thr Glu Glu Glu Lys Ser 515 520 525 Asp Ser Arg Ala Ala * 530 <210> 26 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21102..21308) <400> 26 Met Thr Arg Gln Glu Glu Leu Ala Ala Ala Arg Ala Ala Leu His Asp 1 5 10 15 Leu Met Thr Gly Lys Arg Val Ala Thr Val Gln Lys Asp Gly Arg Arg 20 25 30 Val Glu Phe Thr Thr Thr Ser Val Ser Asp Leu Lys Lys Tyr Ile Ala 35 40 45 Glu Leu Glu Val Gln Thr Gly Met Thr Gln Arg Arg Arg Gly Pro Ala 50 55 60 Gly Phe Tyr Val * 65 <210> 27 <211> 642 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21305..23230) <400> 27 Val Asn Ile Ser Asn Ser Gln Ile Asp Ile Leu Arg Arg Asp Val Arg 1 5 10 15 Ala Gly Leu Arg Ala Leu Phe Arg Pro Glu Pro Gln Thr Ala Val Glu 20 25 30 Trp Ala Asp Ala Ser Tyr Tyr Leu Pro Lys Glu Ser Ala Tyr Gln Glu 35 40 45 Gly Arg Trp Glu Thr Leu Pro Phe Gln Arg Ala Ile Met Asn Ala Met 50 55 60 Gly Ser Asp Tyr Ile Arg Glu Val Asn Val Val Lys Ser Ala Arg Val 65 70 75 80 Gly Tyr Ser Lys Met Leu Leu Gly Val Tyr Ala Tyr Phe Ile Glu His 85 90 95 Lys Gln Arg Asn Thr Leu Ile Trp Leu Pro Thr Asp Gly Asp Ala Glu 100 105 110 Asn Phe Met Lys Thr His Val Glu Pro Thr Ile Arg Asp Ile Pro Ser 115 120 125 Leu Leu Ser Leu Ala Pro Trp Tyr Gly Lys Lys His Arg Asp Asn Thr 130 135 140 Leu Thr Met Lys Arg Phe Thr Asn Gly Arg Gly Phe Trp Cys Leu Gly 145 150 155 160 Gly Lys Ala Ala Lys Asn Tyr Arg Glu Lys Ser Val Asp Val Ala Gly 165 170 175 Tyr Asp Glu Leu Ala Ala Phe Asp Glu Asp Ile Glu Gln Glu Gly Ser 180 185 190 Pro Thr Phe Leu Gly Asp Lys Arg Ile Glu Gly Ser Val Trp Pro Lys 195 200 205 Ser Ile Arg Gly Ser Thr Pro Lys Val Arg Gly Thr Cys Gln Ile Glu 210 215 220 Arg Ala Ala Ser Glu Ser Pro His Phe Met Arg Phe His Val Ala Cys 225 230 235 240 Pro His Cys Gly Glu Glu Gln Tyr Leu Lys Phe Gly Asp Lys Glu Thr 245 250 255 Pro Phe Gly Leu Lys Trp Thr Pro Asp Asp Pro Ser Ser Val Phe Tyr 260 265 270 Leu Cys Glu His Asn Ala Cys Val Ile Arg Gln Gln Glu Leu Asp Phe 275 280 285 Thr Asp Ala Arg Tyr Ile Cys Glu Lys Thr Gly Ile Trp Thr Arg Asp 290 295 300 Gly Ile Leu Trp Phe Ser Ser Ser Gly Glu Glu Ile Glu Pro Pro Asp 305 310 315 320 Ser Val Thr Phe His Ile Trp Thr Ala Tyr Ser Pro Phe Thr Thr Trp 325 330 335 Val Gln Ile Val Lys Asp Trp Met Lys Thr Lys Gly Asp Thr Gly Lys 340 345 350 Arg Lys Thr Phe Val Asn Thr Thr Leu Gly Glu Thr Trp Glu Ala Lys 355 360 365 Ile Gly Glu Arg Pro Asp Ala Glu Val Met Ala Glu Arg Lys Glu His 370 375 380 Tyr Ser Ala Ser Val Pro Asp Arg Val Ala Tyr Leu Thr Ala Gly Ile 385 390 395 400 Asp Ser Gln Leu Asp Arg Tyr Glu Met Arg Val Trp Gly Trp Gly Pro 405 410 415 Gly Glu Glu Ser Trp Leu Ile Asp Arg Gln Ile Ile Met Gly Arg His 420 425 430 Asp Asp Glu Gln Thr Leu Leu Arg Val Asp Glu Ala Ile Asn Lys Thr 435 440 445 Tyr Thr Arg Arg Asn Gly Ala Glu Met Ser Val Ser Arg Ile Cys Trp 450 455 460 Asp Thr Gly Gly Ile Asp Pro Thr Ile Val Tyr Glu Arg Ser Lys Lys 465 470 475 480 His Gly Leu Phe Arg Val Ile Pro Ile Lys Gly Ala Ser Val Tyr Gly 485 490 495 Lys Pro Val Ala Ser Met Pro Arg Lys Arg Asn Lys Asn Gly Val Tyr 500 505 510 Leu Thr Glu Ile Gly Thr Asp Thr Ala Lys Glu Gln Ile Tyr Asn Arg 515 520 525 Phe Thr Leu Thr Pro Glu Gly Asp Glu Pro Leu Pro Gly Ala Val His 530 535 540 Phe Pro Asn Asn Pro Asp Ile Phe Asp Leu Thr Glu Ala Gln Gln Leu 545 550 555 560 Thr Ala Glu Glu Gln Val Glu Lys Trp Val Asp Gly Arg Lys Lys Ile 565 570 575 Leu Trp Asp Ser Lys Lys Arg Arg Asn Glu Ala Leu Asp Cys Phe Val 580 585 590 Tyr Ala Leu Ala Ala Leu Arg Ile Ser Ile Ser Arg Trp Gln Leu Asp 595 600 605 Leu Ser Ala Leu Leu Ala Ser Leu Gln Glu Glu Asp Gly Ala Ala Thr 610 615 620 Asn Lys Lys Thr Leu Ala Glu Tyr Ala Arg Ala Leu Ser Gly Glu Asp 625 630 635 640 Glu * <210> 28 <211> 182 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23205..23750) <400> 28 Met Lys Val Asn Lys Lys Lys Leu Ala Glu Ile Phe Asn Val Asp Pro 1 5 10 15 Arg Thr Ile Glu Arg Trp Gln Ser Gln Gly Leu Pro Cys Val Ser Gly 20 25 30 Gly Gly Lys Gly Val Glu Ser Val Phe Asp Thr Ala Thr Ala Ile Gln 35 40 45 Trp Tyr Ala Gln Arg Glu Ala Asp Ile Glu Asn Glu Lys Leu Arg Lys 50 55 60 Glu Val Glu Asp Tyr Arg Ala Ala Ser Glu Ala Asp Leu Gln Pro Gly 65 70 75 80 Thr Ile Glu Tyr Glu Cys His Arg Leu Thr Arg Ala Gln Ala Asp Ala 85 90 95 Gln Glu Leu Lys Asn Ala Arg Asp Ser Ala Glu Val Val Glu Thr Ala 100 105 110 Phe Cys Thr Phe Val Leu Ser Arg Ile Ala Gly Glu Ile Ala Ser Ile 115 120 125 Leu Asp Gly Ile Pro Leu Ser Val Gln Arg Arg Phe Pro Glu Leu Glu 130 135 140 Asn Arg His Val Asp Phe Leu Lys Arg Asp Ile Ile Lys Ala Met Asn 145 150 155 160 Lys Ala Ala Ala Leu Asp Glu Leu Ile Pro Gly Leu Leu Ser Glu Tyr 165 170 175 Ile Glu Gln Ser Asp * 180 <210> 29 <211> 75 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24137..24361) <400> 29 Met Ser Ser Lys Asn Arg Thr Arg Arg Thr Thr Thr Arg Asn Ile Arg 1 5 10 15 Phe Pro Asn Gln Met Ile Glu Gln Ile Asn Ile Ala Leu Asp Leu Lys 20 25 30 Gly Ser Gly Asn Phe Ser Ala Trp Val Ile Glu Ala Cys Arg Arg Arg 35 40 45 Leu Ile Asn Glu Lys Tyr Ser Gln Phe Val Pro Asn Lys Asp Lys His 50 55 60 Asp Gln Arg Thr Cys Ser Asp Arg Phe Thr * 65 70 <210> 30 <211> 105 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24443..24757) <400> 30 Met Leu His Asp His Leu Ala Glu Cys Leu Glu Lys Lys Gly Leu Tyr 1 5 10 15 Arg Arg Ala Ala Glu Arg Trp Ala Lys Val Met Val Gln Leu Ser Asp 20 25 30 Asp Gln Lys Arg Lys Val Ala Ala Gln Lys Arg Ala Glu Cys Leu Arg 35 40 45 Lys Ala Arg Arg Thr Pro Val Ser Pro Val Asn Leu Thr Glu Ile Lys 50 55 60 Gln Ala Val Asn Arg Leu His Ser Glu Leu Gly Met Gly Phe Glu Glu 65 70 75 80 Arg Arg Val Phe Arg Arg Tyr Lys Gly Thr Gly Glu Gln Asn Thr Ser 85 90 95 Gly Asn Ala Arg Ser Lys Lys Cys * 100 <210> 31 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25283..25468) <400> 31 Met Arg Glu Leu Lys Met Lys Leu Cys Val Leu Met Leu Pro Leu Val 1 5 10 15 Val Ser Ala Cys Ala Ser Thr Pro Thr Val Gln Ala Pro Cys Val Lys 20 25 30 Pro Pro Ser Pro Pro Ala Trp Ile Met Gln Pro Val Pro Asp Trp Gln 35 40 45 Lys Pro Leu Asn Gly Ile Ile Ser Ser Ser Glu Asn Gly * 50 55 60 <210> 32 <211> 153 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25221..25679) <400> 32 Met Leu Ser Ala Phe Thr Val Ile Leu Leu Val Val Cys Gly Ala Leu 1 5 10 15 Ser Leu Gly Leu Asn His Tyr Arg Asp Asn Ala Ile Thr Tyr Lys Glu 20 25 30 Gln Arg Asp Lys Lys Val Ser Glu Leu Glu Leu Ala Asn Ala Thr Ile 35 40 45 Thr Asp Met Gln Gln Arg Gln Arg Asp Val Ala Ala Leu Asp Ala Arg 50 55 60 Tyr Ser Arg Glu Leu Ala Asp Ala Arg Ala Glu Asn Glu Thr Leu Arg 65 70 75 80 Ala Asp Val Ala Ala Gly Arg Lys Arg Leu Arg Ile Asn Ala Asn Cys 85 90 95 Pro Gly Ser Leu Arg Lys Ala Pro Ile Thr Ser Gly Val Asp Asn Ala 100 105 110 Thr Gly Pro Arg Leu Ala Glu Ala Ala Glu Arg Asp Tyr Phe Ile Leu 115 120 125 Arg Glu Arg Leu Met Ala Met Gln Lys Gln Leu Glu Gly Ala Gln Glu 130 135 140 Tyr Ile Arg Thr Gln Cys Ile Pro * 145 150 <210> 33 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25837..26406) <400> 33 Met Asn Met Met Ala Val Pro Phe His Gly Asn Ser Leu Tyr Val Val 1 5 10 15 Asn His Asn Gly Glu Pro Tyr Val Pro Met Lys Pro Val Val Ala Gly 20 25 30 Met Gly Leu Ala Trp Gln Ser Gln Leu Ala Lys Leu Arg Gln Arg Phe 35 40 45 Ala Ser Thr Ile Thr Glu Ile Val Met Val Ala Glu Asp Gly Asn Gln 50 55 60 Arg Asn Met Val Ser Met Pro Leu Arg Lys Leu Ala Gly Trp Leu Gln 65 70 75 80 Thr Ile Asn Pro Asn Lys Val Lys Pro Glu Ile Arg Asp Lys Val Ile 85 90 95 Arg Tyr Gln Glu Glu Cys Asp Asp Val Leu Tyr Glu Tyr Trp Thr Lys 100 105 110 Gly Phe Val Val Asn Pro Arg Lys Met Ser Val Met Glu Glu Leu Asn 115 120 125 Gln Ala Cys Ala Asp Met Lys Arg Asp Lys Asn Ile Ala Ser Val Phe 130 135 140 Ala Thr Gly Leu Asn Glu Trp Lys Gln Val Lys Ala Ala His Val Ser 145 150 155 160 Lys Ile Arg Thr Leu Val Asn Glu Ala Asn Met Leu Ile Asp Phe Val 165 170 175 Leu Ala Asp Thr Gly Lys Gly Lys Ile Thr Lys Ala Asp * 180 185 <210> 34 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26677..27210) <400> 34 Met Asn Ala Lys Ile Arg Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Gly Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Thr Arg Val Asp Gly Lys Pro Val Ile 50 55 60 Pro Gly Met Lys Leu Ser Lys Glu Lys Cys Asp Arg Val Asn Ala Ile 65 70 75 80 Glu Arg Asp Lys Ala Leu Ala Trp Val Glu Lys Asn Ile Arg Val Pro 85 90 95 Leu Thr Glu Pro Gln Lys Ala Gly Ile Ala Ser Phe Cys Pro Tyr Asn 100 105 110 Ile Gly Pro Gly Lys Cys Phe Pro Ser Thr Phe Tyr Arg Arg Ile Asn 115 120 125 Ala Gly Asp Arg Lys Gly Ala Cys Glu Ala Ile Arg Trp Trp Ile Lys 130 135 140 Asp Gly Gly Arg Asp Cys Arg Ile Arg Ser Asn Asn Cys Tyr Gly Gln 145 150 155 160 Val Ser Arg Arg Asp Gln Glu Ser Ala Leu Ala Cys Trp Gly Ile Asp 165 170 175 Arg * <210> 35 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27261..27605) <400> 35 Met Lys Lys Lys Tyr Glu Leu Val Val Lys Gly Ile Asn Asn Tyr Pro 1 5 10 15 Asp Lys Ile Thr Val Thr Val Ala Pro Glu Ile Gly Gly Tyr Pro Ser 20 25 30 Leu Leu Leu Pro Asp Val Ala Ile Ser Leu Asp Arg Thr Glu Gly Ala 35 40 45 Thr Leu Glu Phe Tyr Glu Ala Glu Ala Lys Lys Gln Ala Lys Gln Phe 50 55 60 Phe Met Asp Val Ala Ala Gly Leu Cys Glu Gly Asp Gly Pro Leu Pro 65 70 75 80 Glu Lys Arg Pro Val Ile Leu Glu Ala Gln Asp Val Leu Ile Thr Tyr 85 90 95 Arg Gly Lys Leu Pro Gly Ile Ile Thr Gly Ser Leu Lys Thr Pro Pro 100 105 110 Leu Ala * <210> 36 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27610..27816) <400> 36 Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser Ala Val Gly 1 5 10 15 Thr Gly Tyr Trp Leu Leu Gln Leu Leu Asp Lys Val Ser Pro Ser Gln 20 25 30 Trp Val Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly Leu Leu Thr 35 40 45 Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Lys Glu Asp Arg Arg Lys Ala 50 55 60 Ala Arg Gly Glu * 65 <210> 37 <211> 603 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28307..30115) <400> 37 Met Ser Ile Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Glu Lys Leu Thr His Lys Leu Lys Glu Gly Trp Gln Pro Phe 20 25 30 Gly Ser Pro Val Ala Ile Thr Pro Tyr Thr Leu Met Gln Ala Ile Thr 35 40 45 Ala Glu Gly Asp Val Val Val Ser Gly Ala Thr Glu Pro Asp Trp Tyr 50 55 60 Tyr Val Ile Val Leu Ala Gly Gln Ser Asn Ala Met Ala Tyr Gly Glu 65 70 75 80 Gly Leu Pro Leu Pro Asp Ser Tyr Asp Ala Pro Asp Pro Arg Ile Lys 85 90 95 Gln Leu Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Ala Ala Cys Arg 100 105 110 Tyr Asn Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln Asp 115 120 125 Met Ser Thr Leu Asn His Pro Lys Ala Asp Leu Ser Lys Gly Gln Tyr 130 135 140 Gly Cys Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro Tyr 145 150 155 160 Ile Pro Asn Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly Gly 165 170 175 Ser Ala Phe Thr Gln Gly Ala Glu Gly Ile Phe Ser Glu Ser Thr Gly 180 185 190 Ala Ser Gln Asp Ser Ala Arg Trp Gly Val Gly Lys Pro Leu Tyr Gln 195 200 205 Asp Leu Ile Ala Arg Thr Lys Ala Ala Leu Gln Lys Asn Pro Lys Asn 210 215 220 Val Leu Leu Ala Val Cys Trp Met Gln Gly Glu Phe Asp Met Ser Ala 225 230 235 240 Ala Thr His Ala Gln Gln Pro Ala Leu Phe Thr Ala Met Leu Thr Gln 245 250 255 Phe Arg Ala Asp Leu Ser Val Phe Asn Ala Gln Cys His Gly Gly Ser 260 265 270 Ala Ala Asp Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Tyr Trp Lys 275 280 285 Asn Thr Tyr Ala Thr Gln Tyr Asp Thr Val Tyr Gly Gly Tyr Lys Asn 290 295 300 Arg Glu Ser Glu Gly Val Tyr Phe Val Pro Phe Met Thr Asp Gly Asn 305 310 315 320 Gly Val Asn Thr Ala Thr Asn Ala Pro Ala Glu Asp Pro Asp Ile Pro 325 330 335 Ala Ser Gly Tyr Tyr Gly Ala Ala Ser Arg Thr Asn Gly Asn Gln Val 340 345 350 Ser Ser Asn Arg Pro Thr His Phe Ser Ser Trp Ala Arg Arg Ser Ile 355 360 365 Ile Pro Asp Arg Leu Ala Thr Ala Ile Leu Asn Ala Ala Gly Arg Thr 370 375 380 Ser Ala Phe Ile Ser Gly Lys Ala Pro Glu Ile Lys Pro Ser Pro Gly 385 390 395 400 Gly Asn Thr Pro Ser Gly Pro Ser Ala Asp Thr Ser Val Arg Thr Ile 405 410 415 Ser Leu Leu Pro Ala Ala Gly Glu Ala Ala Ala Gln Gly Trp Ser Ile 420 425 430 Lys Asp Gly Gly Ile Gln Leu Ser Asp Gly Val Phe Lys Ile Thr Arg 435 440 445 Gln Ser Asn Lys Thr Trp Ser Leu Thr His Pro Val Asp Asp Ala Ile 450 455 460 Thr Leu Leu Thr Gln Gly Gly Arg Leu Thr Cys Lys Phe Arg Leu Ser 465 470 475 480 Gly Ala Leu Thr Asn Asn Gln Phe Gly Leu Gly Ile Tyr Leu Tyr Thr 485 490 495 Asp Ala Pro Val Pro Asp Gly Val Ala Met Thr Gly Thr Gly Asn Pro 500 505 510 Phe Leu Met Ser Tyr Phe Thr Gln Thr Thr Asp Gly Arg Val Asn Leu 515 520 525 Met His His Arg Lys Ala Gly Asn Thr Lys Leu Gly Glu Phe Gly Asp 530 535 540 Tyr Gly Asn Asp Trp Gln Thr Leu Glu Leu Val Phe Thr Ala Gly Ser 545 550 555 560 Ala Thr Val Thr Pro Lys Leu Asn Gly Val Ala Gly Pro Ala Phe Gln 565 570 575 Val Ile Lys Asp Ser Leu Thr Leu Gly Leu Asn Ala Leu Thr Leu Thr 580 585 590 Asp Val Thr Lys Asn Ala Ala Tyr Gly Val * 595 600 <210> 38 <211> 144 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30593..31024) <400> 38 Met Phe Gly Ile Phe Lys Lys Lys Thr Arg Arg Ala Ala Thr Glu Ile 1 5 10 15 Lys Lys Phe Glu Lys Arg Asp Leu Ala Gln Val Val Ile Asn Ala Ala 20 25 30 Tyr Leu Val Ala Cys Ala Asp Gly Glu Cys Glu Ala Ser Glu Lys Ala 35 40 45 Lys Ile Glu Gln Val Leu Arg Asn Gln Pro Ala Leu Ser Ala Phe Thr 50 55 60 Ser Glu Ile Asn Ala Ile Ser Ala Thr Ile Ile Gly Gln Leu Asp Thr 65 70 75 80 Asn Phe Lys Thr Gly Arg Arg Ala Ala Leu Arg Glu Ile Glu Asp Val 85 90 95 Lys His Asp Thr Arg Glu Ala Glu Asp Val Leu Asp Val Ala Val Ala 100 105 110 Ile Ala Glu Ala Asp Gly Glu Ile Glu Pro Glu Glu Arg Lys Val Leu 115 120 125 Glu Glu Ile Ala Gly Val Leu Gly Leu Arg Leu Glu Asn His Leu * 130 135 140 <210> 39 <211> 196 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31475..32062) <400> 39 Met His Tyr Gly Lys Val Lys Ile Val Asp Ile Ser Glu Ser Val Val 1 5 10 15 Ser Gln Tyr Leu Glu Ser Gln His Lys Leu Thr Arg Thr Arg Leu Thr 20 25 30 Asp Ile Pro Leu Tyr Leu Leu Leu Glu Pro Asn Asn Pro Ala Leu Ala 35 40 45 Ala Ala Leu Ile Thr Ser Gln Gly Phe Ser Gly Glu Val Thr Asp Met 50 55 60 Phe Leu Met Met Ala Cys Leu Ser Leu Phe Glu Thr Asp Glu Arg Met 65 70 75 80 Ser Leu Phe Leu Ser Gly Cys Leu Ser Ser Ile Ser Ala Lys Val Arg 85 90 95 Ala Ile Ile Gln Thr Asp Ile Ser Ala Ser Trp Thr Leu Gly Ala Ile 100 105 110 Ala Leu Gln Leu His Met Ser Glu Ser Leu Leu Lys Thr Lys Leu Lys 115 120 125 Asn Glu Gly Gly Met Phe Ser Arg Leu Leu Leu Glu Glu Arg Met Arg 130 135 140 Val Ala Val Asn Met Leu Cys Ser Arg Tyr Gly Tyr Gly Gln Ala Val 145 150 155 160 Ala Glu Lys Cys Gly Tyr Ser Ser Arg Ser Tyr Phe Ile Ser Val Phe 165 170 175 His Arg Tyr Tyr Gly Phe Pro Pro Asp Arg Tyr Val Ser Arg Gln Gly 180 185 190 Leu Asp Tyr * 195 <210> 40 <211> 66 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32324..32521) <400> 40 Met Leu Lys Gln Gln Asp Met Thr Glu Thr Ala Arg Val Val Phe Asn 1 5 10 15 Glu Leu Ser Val Thr Glu Pro Ala Thr Val Gly Glu Ile Ala Gln Asn 20 25 30 Thr Tyr Leu Ser Arg Glu Arg Cys Gln Leu Ile Leu Thr Gln Leu Val 35 40 45 Met Ala Gly Leu Ala Asp Tyr Gln Cys Gly Cys Tyr Arg Arg Ile Gln 50 55 60 Ser * 65 <210> 41 <211> 185 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32746..33300) <400> 41 Met Ile Tyr Pro Glu Ile Thr Gly Lys Ser Gly Glu His Leu Arg Leu 1 5 10 15 Lys Thr Leu Glu Ser Val Trp Ile Gln Gly Lys Leu Arg Met Trp Gly 20 25 30 Arg Trp Ser Tyr Ile Gly Asp Gly Lys Thr Gly Asn Met Phe Asn Gln 35 40 45 Leu Leu Thr Ser Lys Lys Leu Thr Lys Thr Ala Ile Asn Glu Ala Leu 50 55 60 Arg Arg Met Lys Lys Ala Gly Leu Asp Lys Pro Glu Leu Glu Ala Phe 65 70 75 80 Leu Arg Asp Met Ile Asn Gly Asn Gln Lys Ser Trp Leu Ala His Cys 85 90 95 Thr Asp Ser Glu Ala Leu Ile Ile Asp Arg Val Ile Gly Glu Val Leu 100 105 110 Ala Gly Tyr Pro Gly Leu Leu Asn Val Leu Ser Gln Arg Tyr Val Gly 115 120 125 Arg Gly Met Thr Lys Arg Lys Met Ala Glu Leu Leu Asn Asp Ala His 130 135 140 Pro Glu Trp Ser Leu Arg Thr Cys Glu Arg Arg Ile Glu His Trp Leu 145 150 155 160 Lys Val Ala Glu Phe Ile Leu Tyr Lys Pro Met Val Met Ala Phe Gly 165 170 175 Ile Glu Lys Lys Val Ile Ala Phe * 180 <210> 42 <211> 102 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33363..33668) <400> 42 Met Arg Ile Glu Phe Val Leu Pro Tyr Pro Pro Thr Val Asn Thr Tyr 1 5 10 15 Trp Arg Arg Arg Gly Ser Thr Tyr Phe Val Ser Lys Ala Gly Glu Arg 20 25 30 Tyr Arg Arg Asp Val Ala Leu Ile Val Arg Gln Gln Arg Leu Lys Leu 35 40 45 Asn Leu Ser Gly Arg Leu Ala Ile Lys Ile Ile Ala Glu Pro Pro Asp 50 55 60 Lys Arg Arg Arg Asp Leu Asp Asn Ile Leu Lys Ala Pro Leu Asp Ala 65 70 75 80 Leu Thr His Ala Gly Leu Leu Ile Asp Asp Glu Gln Phe Asp Glu Ile 85 90 95 Asn Ile Val Arg Gly * 100 <210> 43 <211> 361 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33681..34763) <400> 43 Met Pro Ala Thr Val Ser Ala Ser Gly Gly Asn Val Arg Val Leu Leu 1 5 10 15 Arg Pro Val Leu Val Pro Glu Leu Gly Leu Val Val Leu Lys Pro Gly 20 25 30 Arg Glu Ser Leu Pro Val Phe His Arg Gly Arg Val Leu Val Glu Pro 35 40 45 Glu Pro Lys Asn Met Arg Ala Leu Pro Ser Gly Ala Val Pro Ala Val 50 55 60 Arg Gln Pro Leu Ala Glu Asp Lys Ser Leu Leu Pro Phe Phe Ser Asp 65 70 75 80 Glu Arg Val Ile Arg Ala Ala Gly Gly Ala Gly Ala Leu Ser Asp Trp 85 90 95 Leu Leu Arg His Val Lys Ser Cys Gln Trp Pro His Gly Asp Tyr His 100 105 110 His Ser Glu Thr Val Ile His Ser Tyr Gly Ala Gly Ala Met Val Leu 115 120 125 Cys Trp His Cys Asp Asn Gln Leu Arg Asp Gln Thr Ser Glu Ser Leu 130 135 140 Glu Gln Leu Thr Gln Gln Asn Leu Thr Ala Trp Met Ile Asp Val Ile 145 150 155 160 Arg His Val Met Asn Gly Thr Gln Glu Arg Glu Leu Ser Leu Ala Glu 165 170 175 Leu Ser Trp Trp Ala Val Cys Asn Gln Val Val Asp Ala Leu Pro Glu 180 185 190 Ala Val Ser Arg Arg Ser Leu Gly Leu Pro Ala Glu Lys Ile Arg Ser 195 200 205 Val Tyr Arg Glu Ser Asp Ile Ile Pro Gly Glu Gln Thr Ala Thr Ser 210 215 220 Ile Leu Lys Gln Arg Thr Lys Asn Ile Ala Leu Pro Pro His Thr His 225 230 235 240 Gln Gln Gln Asn Pro Pro Gln Glu Lys Thr Val Val Ser Ile Ala Val 245 250 255 Asp Pro Glu Ser Pro Glu Ser Phe Met Lys Arg Pro Lys Arg Arg Arg 260 265 270 Trp Val Asn Glu Lys Tyr Thr Arg Trp Val Lys Thr Gln Pro Cys Ala 275 280 285 Cys Cys Gly Lys Pro Ala Asp Asp Pro His His Leu Ile Gly His Gly 290 295 300 Gln Gly Gly Met Gly Thr Lys Ser His Asp Ile Phe Thr Leu Pro Leu 305 310 315 320 Cys Arg Glu His His Asn Glu Leu His Ala Asp Pro Leu Ala Phe Glu 325 330 335 Glu Lys His Gly Ser Gln Val Asp Leu Ile Phe Arg Phe Leu Asp His 340 345 350 Ala Phe Ala Thr Gly Val Leu Gly * 355 360 <210> 44 <211> 91 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34732..35004) <400> 44 Met Thr Gln His Ile Lys Ser His Asn Ser Glu Ala Asp Pro Glu Ile 1 5 10 15 Lys Gln Gly Arg Arg Phe Arg Ala Pro Gln Tyr Gly Trp Phe His Tyr 20 25 30 Leu Phe Cys Thr Ile Asp Glu Ala Asp Met Leu Gln Glu Ala Tyr Leu 35 40 45 Arg Arg Gly Val Arg Val Glu Arg Ser Leu Asn Ala Asp Arg Leu Thr 50 55 60 Trp Thr Val Ser Val Tyr Leu Pro Val Arg Ala His Leu Pro Arg Thr 65 70 75 80 His Ala Cys Tyr Arg Gln Arg Val Trp Arg * 85 90 <210> 45 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35126..35470) <400> 45 Met Lys Lys Val Leu Ile Ala Ala Leu Ile Ser Gly Val Ser Phe Gly 1 5 10 15 Ala Phe Ala Gln Gln Gly Gly Phe Gln Gly Pro Glu Ala Glu Arg Ser 20 25 30 Thr Val Ala Gln Ala Lys Glu Leu Lys Asp Asp Ala Trp Val Ile Leu 35 40 45 Glu Gly Ser Ile Val Lys Lys Val Gly Asp Glu Arg Tyr Glu Phe Arg 50 55 60 Asp Asn Ser Gly Thr Ile Val Thr Asp Ile Asp Asp Ser Val Trp Ala 65 70 75 80 Gly Gln Asn Val Ser Pro Lys Asp Lys Val Arg Ile Glu Gly Glu Ile 85 90 95 Asp Lys Asp Leu Ser Ser Val Glu Val Asp Val Lys Ala Leu Lys Leu 100 105 110 Leu Lys * <210> 46 <211> 71 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35590..35802) <400> 46 Met Leu Asn Thr Cys Arg Leu Ala Ser Tyr Val Pro Lys Gly Lys Glu 1 5 10 15 Lys Gln Ala Met Lys Gln Gln Lys Ala Met Leu Ile Ala Leu Ile Val 20 25 30 Ile Cys Leu Thr Val Ile Val Thr Ala Leu Val Thr Arg Lys Asp Leu 35 40 45 Cys Glu Val Arg Ile Arg Thr Gly Gln Thr Glu Val Ala Val Phe Val 50 55 60 Asp Tyr Glu Ser Glu Lys * 65 70 <210> 47 <211> 186 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36036..36593) <400> 47 Met Ser Thr Ile Thr Arg Glu Arg Ala Glu Ile Lys Ser Tyr Ile Thr 1 5 10 15 Gly Phe Leu Ser Asp Ser Ala His Asp Asn Lys Ser Ser Asp Ser Leu 20 25 30 Leu Ala Asn Val Phe Arg Ile Ala Leu Ala Ser Leu Glu Ala Glu Pro 35 40 45 Ile Ala Met Val Val Pro Asp Glu Met Asp Leu Leu Thr Cys His Leu 50 55 60 Asp Gly Val Thr Lys Thr Tyr Ala Asp Gly Trp Asn Ala Cys Arg Val 65 70 75 80 Ala Met Leu Gln Ala Gly Asn Phe Arg Glu Asn Lys Asn Ser Ser Thr 85 90 95 Asn Asn Phe Arg Glu Ile Ser Glu Thr Ser Thr Arg Ser Pro Ile Thr 100 105 110 Leu Asp Gly Trp Ile Ser Cys Thr Glu Arg Met Pro Glu Lys Ser Gln 115 120 125 Asn Val Leu Ile Ser Met Asn Ile Asp Ser Glu Ala Gly Pro Leu Ile 130 135 140 Tyr Ser Ala Arg Tyr Leu Gly Gly Thr Phe Arg Arg Gly Gly Ile Ala 145 150 155 160 Val Ser Pro Gly Asn Asp Leu Arg Gln Ala Thr His Trp Met Ser Leu 165 170 175 Pro Glu Pro Pro Gln Glu Val Asn Gln * 180 185 <210> 48 <211> 73 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36595..36813) <400> 48 Met Lys His Tyr Leu Glu Lys Asn Tyr Pro Arg Lys Ser Arg Thr Thr 1 5 10 15 Glu Phe Leu Phe Phe Ile Leu Phe Ile Val Leu Met Ile Pro Ile Ser 20 25 30 Pro Leu Leu Leu Val Trp Ile Ile Gly Arg Thr Phe Glu Pro Val Ile 35 40 45 Glu Leu Tyr Thr Asp Val Thr Trp Glu Ser Phe Ser Ala Leu His Asn 50 55 60 Lys Ile Asn Pro Tyr Lys Glu Asn * 65 70 <210> 49 <211> 104 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36941..37252) <400> 49 Val Ser Glu Ile Lys Glu Met Pro Val Val Arg Asp Gly Tyr Gly Tyr 1 5 10 15 Trp Thr His Pro Glu Tyr Glu Lys Phe Cys Asp Gly Arg Glu Tyr Ile 20 25 30 Ser Thr Glu Glu Phe Asn Ala Trp Met Glu Glu Asn Asn Leu Gln Tyr 35 40 45 Val Leu Cys Phe Arg Asp Glu Gly Cys Ala Asp Leu Asp Ala Cys Asp 50 55 60 Ala Asp Ile Ser Ala Trp Glu Pro Glu Arg Pro Glu Gly Asp Gly Trp 65 70 75 80 Phe Ile Gly Ser Ile His Asp Thr Glu Asp Gly Pro Val Cys Val Trp 85 90 95 Leu Arg Asn Lys Ala Glu Ala * 100 <210> 50 <211> 76 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37245..37472) <400> 50 Val Lys Ile Leu Tyr Gln Asp Tyr Gly Pro Val Gly Gln Val Val Ile 1 5 10 15 Ser Ser Thr Val Met Glu Phe Arg Lys His Asn Arg Val Val Asp Ala 20 25 30 Val Leu Leu Thr Cys Pro Gly Ile Ser Ala Ser Arg Ala Gly Val Phe 35 40 45 Ile Met Lys Thr Lys Leu Tyr Gly Ser Lys Ala Trp Ile Lys Lys Ala 50 55 60 Tyr Arg Val Ala Leu Gln Glu Val Asn Ser Glu * 65 70 75 <210> 51 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37469..37750) <400> 51 Met Ile Leu Arg Gln Cys Ala Gly Thr Met Lys Val Lys Ser Val Gly 1 5 10 15 Ala Leu Ile Gly Arg Thr Glu Ala Ala Val Arg Thr Lys Ala Arg Glu 20 25 30 Leu Gly Ile Ser Met Met Leu Arg Gly Asp Phe His Pro Ser Ala Lys 35 40 45 Tyr Ser Gln Arg Asp Ile Glu Leu Ala Arg Gln Leu His Gln Arg Gly 50 55 60 Met Gln Arg Arg Glu Ile Ala Arg Lys Leu Gly Met Pro Leu Arg Ile 65 70 75 80 Val Asn Asn Tyr Val Tyr Phe Asp Arg Arg Val Ser Ala * 85 90 <210> 52 <211> 245 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37783..38517) <400> 52 Leu Ser Glu Glu Ile Leu Met Glu Thr Val Phe Asp Ala Leu Lys Ala 1 5 10 15 Leu Lys Lys Ala Ser Ser Gln Val Val Ala Ser Arg Leu Gly Ile Ser 20 25 30 Arg Glu Asp Ala Val Asn Glu Leu Trp Lys Leu Lys Arg Arg Gly Glu 35 40 45 Ala Asp Asn Lys Gly Ser Met Trp Trp Leu Thr Gln Thr Gly Glu Ser 50 55 60 Glu Pro Val Ser Pro Val Pro Lys Val Thr Ala Gln Met Leu Thr Glu 65 70 75 80 Ala Ile Glu His His Gly Pro Gln Thr Ala Asp Glu Leu Ala Leu Met 85 90 95 Phe Gly Ile Thr Ser Arg Arg Ala Asn Ser Ser Leu Ala Met Ala Ile 100 105 110 Ser Lys Gly Arg Leu Ile Arg Val Asn Gln Gly Gly Lys Phe Arg Tyr 115 120 125 Cys Ile Pro Gly Ala Asp Leu Pro Ala Glu Pro Lys Ala Ala Ser Ile 130 135 140 Thr Glu Thr Asp Gly Lys Ala Phe Pro Gln Pro Ala Gly Val Ala Leu 145 150 155 160 Pro Val Gly Glu Ala Glu Thr Gln Glu Glu Ile Lys Thr Glu Ser Val 165 170 175 Ala Val Thr Val Gln Ser Gln Pro Ser Phe Thr Arg Lys His Pro Asp 180 185 190 Gly Leu Ile Leu Pro Ser Leu His Val Ala Asn Arg Glu Leu Arg Arg 195 200 205 Ala Lys Gly Gln Val Gln Lys Trp Glu Arg Val Cys Ala Ala Leu Arg 210 215 220 Glu Leu Asn Lys Cys Arg Asp Ile Leu Arg Asp Ile Thr Ala Thr Arg 225 230 235 240 Glu Gln Gln Arg * <210> 53 <211> 221 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38533..39195) <400> 53 Met Gln His Gln Val Ala Arg His His Gly Gln Phe Arg Lys Ser Gly 1 5 10 15 Leu His Ala Asn Ser Gly Asn Val Thr Thr Asp Leu Ser Ala Thr Glu 20 25 30 Thr Ala Trp Lys Leu Trp Glu Leu Met Gly Glu Val Tyr Ser Asn Arg 35 40 45 Trp Thr Gln Lys Asn Gly Ala Ala Pro Ser Lys Leu Trp Ile Ala Gln 50 55 60 Ile Gly Ala Met Thr Glu Gln Gln Ile Arg Leu Val Cys Arg Gln Cys 65 70 75 80 Met Asp Arg Cys Arg Ala Gly Glu Thr Trp Pro Pro Asp Leu Ala Glu 85 90 95 Phe Val Ala Leu Ile Ser Glu Ser Gly Ala Asn Pro Phe Gly Leu Thr 100 105 110 Val Asp Ala Val Met Glu Glu Tyr Arg Arg Trp Arg Asn Glu Ser Trp 115 120 125 Arg Tyr Asp Gly Ser Asp Lys Tyr Pro Trp Pro Gln Pro Val Leu Tyr 130 135 140 His Ile Cys Leu Glu Met Arg Thr Arg Gly Ile Glu Arg Gln Met Thr 145 150 155 160 Gln Gly Glu Leu Lys Arg Leu Ala Glu Arg Gln Leu Thr Lys Trp Ala 165 170 175 Lys His Val Gly Asn Gly Met Ser Val Pro Pro Val Arg Arg Gln Leu 180 185 190 Glu Gly Ala Lys His Pro Gln Gly Pro Thr Pro Ile Glu Arg Leu Lys 195 200 205 Gln Glu Tyr Glu Arg Arg Lys Ala Ala Gly Phe Ile * 210 215 220 <210> 54 <211> 348 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38987..40030) <400> 54 Met Ala Asn Ala Trp Leu Arg Leu Trp His Asp Met Pro Asn Asp Pro 1 5 10 15 Lys Trp Arg Thr Ile Ala Arg Val Ser Gly Gln Pro Ile Ala Thr Val 20 25 30 Met Ala Val Tyr Ile His Leu Leu Val Ser Ala Ser Arg Asn Val Thr 35 40 45 Thr Cys His Gly Val Ser Leu Arg Gly His Ile Asp Val Thr Thr Glu 50 55 60 Asp Leu Ala Ser Ala Leu Asp Val Thr Glu Asp Val Ile Asp Ser Ile 65 70 75 80 Leu His Ala Met Gln Gly Arg Val Leu Asp Gly Asp Leu Ile Ser Gly 85 90 95 Trp Glu Lys Arg Gln Val Leu Lys Glu Asp Asn Gly Asn Val Ser Gln 100 105 110 Thr Ala Lys Ser Pro Ala Glu Arg Lys Arg Ala Gln Arg Glu Arg Glu 115 120 125 Lys Leu Arg Lys His Asn Ala Asp Cys His Asp Glu Ser Arg Arg Val 130 135 140 Thr His Leu Ser Arg Gln Val Thr Thr Asp Lys Asp Thr Asp Lys Asp 145 150 155 160 Thr Asp Thr Glu Leu Asn Pro Thr His Asn Ala Arg Glu Ser Ile Pro 165 170 175 Thr Ser Glu Ser Asn Gly Ala Pro Leu Gln Thr Ala Glu Pro Glu Tyr 180 185 190 Leu Asp Gly Leu Ser Glu Pro Ile Gly Lys Phe Ser Met Thr Thr Val 195 200 205 Trp Gln Pro Ser Pro Asp Phe Arg Gln Arg Ala Ala Val Trp Gly Met 210 215 220 Ala Leu Pro Glu Pro Glu Phe Thr Pro Ala Glu Leu Ala Ala Phe Arg 225 230 235 240 Asp Tyr Trp Met Ala Glu Gly Lys Val Phe Thr Gln Val Gln Trp Glu 245 250 255 Gln Lys Phe Ala Arg His Val Gln His Val Arg Ala Gln Val Lys Pro 260 265 270 Val Ser Lys Gly Gly Ser His Ala Ala Ser Gly Gly Thr Ala Ser Arg 275 280 285 Ala Val Gln Glu Ile Arg Ala Ala Arg Glu Gln Trp Glu Arg Asp Asn 290 295 300 Gly Phe Ile Ser Asn Gly Asn Gly Leu Glu Ala Val Gly Ala His Gly 305 310 315 320 Gly Gly Val Phe Glu Pro Leu Asp Ser Glu Glu Arg Gly Arg Thr Phe 325 330 335 Glu Ala Leu Asp Cys Pro Asp Trp Cys Asp Asp * 340 345 <210> 55 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40099..40524) <400> 55 Met Lys Ile Lys His Glu His Ile Arg Met Ala Met Asn Ala Trp Ala 1 5 10 15 Arg Pro Asp Gly Glu Lys Val Pro Ala Ala Gly Ile Thr Gln Ala Tyr 20 25 30 Phe Glu Leu Gly Met Thr Phe Pro Glu Leu Tyr Asp Asp Ser His Pro 35 40 45 Glu Ala Leu Ala Arg Asn Thr Gln Lys Ile Phe Arg Trp Ile Glu Lys 50 55 60 Asp Thr Pro Asp Ala Val Glu Lys Met Gln Ala Leu Leu Pro Ala Ile 65 70 75 80 Glu Lys Ala Met Pro Pro Leu Leu Val Ala Arg Met Arg Ser His Ser 85 90 95 Ser Glu Tyr Tyr Arg Glu Ile Val Glu Arg Arg Asp Arg Leu Val Lys 100 105 110 Asp Val Asp Asp Phe Val Ala Ala Ala Ile Ala Trp Gly Thr Leu Thr 115 120 125 Asn Ser Gly Gly Gln Pro Gly Asn Ala Val Val Val His * 130 135 140 <210> 56 <211> 81 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40508..40750) <400> 56 Met Lys Lys Ser Glu Val Leu Gly Tyr Phe Gly Gly Val Val Lys Thr 1 5 10 15 Ala Ala Ala Leu Gly Thr Ser Lys Thr Thr Val Ser Met Trp Gly Glu 20 25 30 Asp Val Pro Trp Lys Trp Ala Leu Leu Ile Gln Ala Val Thr Ala Gly 35 40 45 Ala Leu Lys Tyr Glu Leu His Ile Pro Thr Val Val Ile Pro Asp Ser 50 55 60 Asp His Asn Pro Pro Ser Asn Gln Gly Gly Ile His Glu Asn Gln Ala 65 70 75 80 * <210> 57 <211> 175 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40956..41480) <400> 57 Met Asn Gly Gly Gly Ala Pro Ser Ser Arg Tyr Ile Ser Ser Leu Ala 1 5 10 15 Lys Ile Leu Lys Val Asn Glu Asn Trp Leu Leu Asn Gly Gly Glu Leu 20 25 30 Asn Thr Gly Asp Ser Leu Asp Leu Ser Leu Pro Pro Ile Lys Thr Val 35 40 45 Pro Leu Leu Ser Leu Gln Gln Ala Ala Ser Trp Ser Asp Tyr Met Lys 50 55 60 Asn Ser Ser Ile Thr Ser Cys Val Gln Leu Val Gly Glu Ile Pro Ala 65 70 75 80 Asn Thr Phe Ala Val Val Leu Glu Ser Asp Ser Met Ser Thr Ser Gly 85 90 95 Gly Gly Val Ser Ile Pro Asn Gly Ser Thr Val Phe Val Asp Pro Asp 100 105 110 Arg Ile Val Gln Pro Gly Asn Ile Val Leu Ala Leu Pro Lys Gly Thr 115 120 125 Thr Thr Pro Val Ile Arg Lys Leu Glu Ile Glu Gly Pro Asp Ile Leu 130 135 140 Leu Val Pro Thr Asn Pro Arg Tyr Pro Ser Ile Met Leu Asp Asp Leu 145 150 155 160 Ser Cys Ile Leu Gly Val Cys Phe Lys Ile Gln Gln Asp Ile * 165 170 <210> 58 <211> 78 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41692..41925) <400> 58 Met Thr Ala Gly Phe Asn Phe Asn Asn Tyr Ala Ala Gly Phe Cys Ser 1 5 10 15 Ala Thr Pro Ala Leu Arg Gly Asn Glu Val Asn Met Asp Thr Leu Asn 20 25 30 Leu Gly Asn Asn Glu Ser Leu Val Cys Gly Val Phe Pro Asn Gln Asp 35 40 45 Gly Thr Phe Thr Ala Met Thr Tyr Thr Lys Ser Lys Thr Phe Lys Thr 50 55 60 Glu Ala Gly Ala Arg Arg Trp Leu Ala Arg Asn Thr Asp * 65 70 75 <210> 59 <211> 213 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41937..42575) <400> 59 Met Glu Phe Lys Asp Leu Pro Pro Ser Ile Gln Glu Ile Ala Ala His 1 5 10 15 Thr Leu Arg His Arg Leu Asn Glu Leu Glu Leu Glu Ser Val Thr Lys 20 25 30 Lys Asp Thr Asp Asn Met Ala Arg Asn Val Arg Asp Ala Phe Thr Gly 35 40 45 Leu Tyr Phe Cys Ala Ser Ile Asn Lys His Asp Ser Glu Ser Val Ala 50 55 60 Asn Lys Ile Ala Glu Thr Thr Ala Gln Asn Ile Asn Thr Lys Pro Thr 65 70 75 80 Glu Glu Glu Ile Asp Gln Phe Ala His Asp Ala Gly Leu Lys Asn Lys 85 90 95 Lys Glu Lys Ser Pro Tyr Ala Gly Asn Met Phe Val Tyr Asp Asn Leu 100 105 110 Ile Arg Ile Arg Gly Glu Ile Pro Ala Glu Tyr Leu Ala Arg Val His 115 120 125 Gln Ala Leu Leu Lys Asn Leu Glu Thr Glu Leu Phe Asp Gly Asn Thr 130 135 140 Asn Gly Phe Phe Met Val Ser Gly Leu Glu Lys Asp Trp Asp Ala Glu 145 150 155 160 Lys Arg Trp Asn Val Ala Thr Trp Leu Phe Ser Asn Arg Ala Ala Ala 165 170 175 Leu Glu Ala Ser Ala Cys Ile Cys Gly Leu Phe Leu Thr Asp His Lys 180 185 190 Tyr Asn Leu Asp Val Tyr Ser Tyr Ile Tyr Ala Glu His Gly Pro Leu 195 200 205 Trp Ile Asp Trp * 210 <210> 60 <211> 70 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42576..42785) <400> 60 Met Pro Asn Lys Lys Arg Asn Pro Leu Ile Glu Lys Gln Ile Glu Cys 1 5 10 15 Leu Val Asn Gln Leu Arg Gln Ser Gly Leu Leu Lys Thr His Ser Glu 20 25 30 Leu Arg Leu Thr Glu Ser Ala Phe Asp Asp Lys Leu Asn Asn Val Leu 35 40 45 Tyr Asn Gly Ile Ile Asp Phe Asn Arg Ser Val Gly Arg Arg Gly Pro 50 55 60 Ala Gly Val Ser Leu * 65 <210> 61 <211> 87 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42834..43094) <400> 61 Leu Ser Leu Lys Arg Met Val Asn Leu Thr Thr Arg Cys Pro Gln Trp 1 5 10 15 Gly Arg Asn Asn Pro Ala Ile Leu Thr Ala Ala Pro Phe Arg Gly Val 20 25 30 Pro Gln Pro Glu Ala His Val Arg Arg Asn Leu Thr Thr Ser Leu Leu 35 40 45 Arg Glu Arg Ala Ser Pro Tyr Ala Phe Ala Leu Cys Thr Asp Phe Ser 50 55 60 Gly Lys Tyr Pro Phe Ser Lys Leu Ser Val Pro Asp Ser Tyr Pro Cys 65 70 75 80 Pro Ala His Asp His Thr * 85 <210> 62 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43350..43538) <400> 62 Met Glu Thr Leu Leu Pro Asn Val Asn Thr Ser Glu Gly Cys Phe Asp 1 5 10 15 Ile Gly Val Leu Leu Ser Asn Arg Glu Phe Thr Glu Asp Ala Ile Asn 20 25 30 Met Arg Lys Tyr Glu Pro Tyr Leu Leu Asn Asp Asn Ser Ile Leu Ser 35 40 45 Arg Ile Ala Leu Leu Glu Leu Gly Ile Phe Gly Glu Arg Gln * 50 55 60 <210> 63 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43535..43723) <400> 63 Met Thr Ser Ala Phe Ala Leu Met Met Thr Val Phe Leu Ile Thr Gly 1 5 10 15 Glu Ser Gln Asn Val Ile Thr Gly Ile Tyr Ala Ser Lys Glu Ser Cys 20 25 30 Leu Gln Ala Arg Asp Glu Gln Lys Ile Ser Gly Glu Cys Leu Pro Val 35 40 45 Lys Lys Val Ser Leu Tyr Leu Asn Asn Glu Thr Pro Ala Gly * 50 55 60 <210> 64 <211> 415 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43816..45060) <400> 64 Met Ser Thr Asp Lys Glu Glu Phe Ala Leu Tyr Cys Glu Ala Lys Asn 1 5 10 15 Asp Lys Val Arg Lys Arg Leu Gly Ile Lys Gly Gly Phe Tyr Trp Thr 20 25 30 Thr Ala Lys Lys Leu Ser Val Ala Ile Ser Arg Cys Ile Thr Ala Met 35 40 45 Asp Asp Asn Asp Tyr Asp Glu Asp Asp Phe Lys Lys Pro Val Arg Val 50 55 60 His Leu Pro Val Val Asn Asp Leu Pro Pro Glu Gly Val Phe Asp Thr 65 70 75 80 Glu Phe Cys Asn Arg Tyr Glu Lys Gly Gly Glu Asp Gly Ile Thr Met 85 90 95 Val Phe Ile Ala Pro Ser Pro Ser Val Gln Glu Lys Pro Ala Ser Thr 100 105 110 Asp Asn Thr Asn Val Asn Gly Glu Asp Met Thr Glu Ile Glu Glu Asn 115 120 125 Met Leu Leu Pro Val Ser Gly Gln Glu Leu Pro Ile Arg Trp Leu Ala 130 135 140 Gln His Gly Ser Glu Lys Pro Val Thr His Val Ala Arg Glu Glu Leu 145 150 155 160 Gln Ala Leu His Ile Ala Arg Ala Glu Glu Leu Pro Ala Val Thr Ala 165 170 175 Leu Ala Ile Ser His Lys Thr Lys Leu Leu Asp Pro Leu Glu Ile Arg 180 185 190 Asp Leu His Lys Leu Val Arg Asp Thr Asp Lys Val Phe Pro Asn Pro 195 200 205 Gly Asn Ser Asp Leu Gly Leu Ile Thr Ala Phe Phe Glu Ala Tyr Leu 210 215 220 Asp Ala Asp Tyr Thr Asp Arg Gly Leu Leu Thr Lys Glu Trp Met Lys 225 230 235 240 Gly Asn Arg Val Ser Arg Ile Thr Arg Thr Ala Ser Gly Ala Asn Ala 245 250 255 Gly Gly Gly Asn Lys Thr Asp Arg Asn Pro Asn Leu Val His Thr Phe 260 265 270 Asp Thr Leu Asp Val Glu Ile Ala Ala Ala Thr Leu Pro Met Asp Phe 275 280 285 Asn Ile Tyr Glu Ile Pro Gly Ser Val Tyr Arg Arg Ala Lys Glu Ile 290 295 300 Val Leu Lys Arg Glu Ser Pro Phe Lys Glu Trp Ser Ala Ala Leu Arg 305 310 315 320 Ala Thr Pro Gly Ile Leu Asp Tyr Ser Arg Ala Ala Ile Phe Ala Leu 325 330 335 Ile Arg Ser Ala His Pro Glu Phe Tyr His Tyr Pro Gly Arg Leu Gln 340 345 350 Gly Tyr Ile Asn Ala Tyr Leu Thr Glu Thr Asp His Glu Asn Pro Ser 355 360 365 Lys Glu Thr Leu Thr Ala Ala Arg His Thr Pro Glu Lys Asp Ile Leu 370 375 380 Glu Glu Val Asn Arg Glu Leu Ser Ala Lys Gln Glu Thr Glu Glu Glu 385 390 395 400 Asn Asp Glu Glu Lys Pro Gln Pro Ser Cys Ala Met Ala Glu * 405 410 <210> 65 <211> 184 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45042..45593) <400> 65 Leu Arg Asn Gly Arg Met Ile Ile Arg Arg Asn Leu Ala Lys Asp Arg 1 5 10 15 Phe Thr Val Pro Lys Thr Gln Ala Gly Thr Asn Arg Val Ile His Leu 20 25 30 Ile Lys Pro Ala Ile Asp Ala Leu Arg Ser Gln Met Ala Leu Thr Arg 35 40 45 Leu Ser Lys Glu His Ile Ile Asp Val His Leu Arg Glu Phe Gly Arg 50 55 60 Thr Glu Lys Gln Lys Cys Thr Phe Val Phe Gln Pro Glu Val Ser Ala 65 70 75 80 Lys Val Lys Asn Tyr Gly Asp His Phe Thr Val Asp Ser Ile Arg Gln 85 90 95 Met Trp Asp Ala Ala Val Lys Arg Ala Gly Ile Arg His Arg Lys Ser 100 105 110 Tyr Gln Ser Arg His Thr Tyr Ala Cys Trp Ser Leu Thr Ala Gly Ala 115 120 125 Asn Pro Ala Phe Ile Ala Asn Gln Met Gly His Ala Asp Ala Gln Met 130 135 140 Val Phe Gln Val Tyr Gly Lys Trp Met Ser Glu Asn Asn Asn Ala Gln 145 150 155 160 Val Thr Leu Leu Asn Thr Gln Leu Ser Glu Phe Ala Pro Thr Met Pro 165 170 175 His Asn Glu Ala Met Lys Ser * 180 <210> 66 <211> 85 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45699..45953) <400> 66 Met Val Val Phe Phe Leu Lys Ile Pro Asn Leu Asp Phe Ala Val Tyr 1 5 10 15 Leu Arg Pro Phe Tyr Val Pro Tyr Met Pro His Arg Tyr Pro Ala Ala 20 25 30 Lys Ile Asn Lys Met Pro Lys Gly Ser Val Pro Ala Leu Gln Gln Glu 35 40 45 Met Leu Arg Arg Val Ser Lys Arg Tyr Asp Asp Val Glu Val Ile Ile 50 55 60 Lys Ser Thr Ser Asn Asp Gly Leu Glu Pro Pro Arg Phe Ser Trp Arg 65 70 75 80 Val Phe Tyr Leu * <210> 67 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45956..46846) <400> 67 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 68 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46843..47169) <400> 68 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 69 <211> 290 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(47376..48245) <400> 69 Leu Ser Asn Ser Ser Asp Ser Asp Gln Thr Val Gln Ala Val Arg Leu 1 5 10 15 Pro Asp Val Ser Pro Ala Leu Val Ser Lys Val Thr Asp Ala Val Met 20 25 30 Glu Gln Val Val Glu Trp Gln Asn Arg Pro Leu Asp Ala Val Tyr Pro 35 40 45 Ile Val Tyr Leu Asp Cys Ile Val Leu Lys Val Arg Gln Asp Ser Arg 50 55 60 Val Ile Asn Lys Ser Val Phe Leu Ala Leu Gly Ile Asn Ile Glu Gly 65 70 75 80 Gln Lys Glu Leu Leu Gly Met Trp Leu Ala Glu Asn Glu Gly Ala Lys 85 90 95 Phe Trp Leu Asn Val Leu Thr Glu Leu Lys Asn Arg Gly Leu Asn Asp 100 105 110 Ile Leu Ile Ala Cys Val Asp Gly Leu Lys Gly Phe Pro Asp Ala Ile 115 120 125 Asn Thr Val Tyr Pro Glu Ala Arg Ile Gln Leu Cys Ile Val His Met 130 135 140 Val Arg Asn Ser Leu Arg Phe Val Ser Trp Lys Asp Tyr Lys Ala Val 145 150 155 160 Thr Arg Asp Leu Lys Ala Ile Tyr Gln Ala Pro Thr Glu Glu Ala Gly 165 170 175 Gln Gln Ala Leu Glu Ala Phe Ala Ser Ala Trp Asp Ser Arg Tyr Pro 180 185 190 Gln Ile Ser Arg Ser Trp Gln Ala Asn Trp Thr Asn Leu Ala Met Phe 195 200 205 Phe Ala Tyr Pro Ala Asp Ile Arg Lys Val Ile Tyr Thr Thr Asn Ala 210 215 220 Ile Glu Ser Leu Asn Ser Val Ile Arg His Ala Ile Lys Lys Arg Lys 225 230 235 240 Val Phe Pro Thr Asp Asp Ser Val Lys Lys Val Val Trp Leu Ala Ile 245 250 255 Gln Ala Ala Ser Gln Lys Trp Thr Met Pro Leu Arg Asp Trp Arg Met 260 265 270 Ala Met Ser Arg Phe Ile Ile Glu Phe Gly Asp Arg Leu Asp Gly His 275 280 285 Phe * <210> 70 <211> 127 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48289..48669) <400> 70 Met Gln Lys Asn Val Thr Pro Gly Arg Arg Lys Gly Cys Pro Asn Tyr 1 5 10 15 Pro Pro Glu Phe Lys Gln Gln Leu Val Ala Ala Ser Cys Glu Pro Gly 20 25 30 Ile Ser Ile Ser Lys Leu Ala Leu Glu Asn Gly Ile Asn Ala Asn Leu 35 40 45 Leu Phe Lys Trp Arg Gln Gln Trp Arg Glu Gly Lys Leu Leu Leu Pro 50 55 60 Ser Ser Glu Ser Pro Gln Leu Leu Pro Val Thr Leu Asp Ala Ala Ala 65 70 75 80 Glu Gln Pro Glu Ser Leu Ala Glu Asp Pro Glu Thr Leu Ser Ile Ser 85 90 95 Cys Glu Val Thr Phe Arg His Gly Thr Leu Arg Phe Asn Gly Asn Val 100 105 110 Ser Glu Lys Leu Leu Thr Leu Leu Ile Gln Glu Leu Lys Arg * 115 120 125 <210> 71 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48666..49013) <400> 71 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Asp Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 72 <211> 513 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(49063..50601) <400> 72 Met Asn Asp Ile Ser Ser Asp Asp Ile Phe Leu Leu Lys Gln Arg Leu 1 5 10 15 Ala Glu Gln Glu Ala Leu Ile His Ala Leu Gln Glu Lys Leu Ser Asn 20 25 30 Arg Glu Arg Glu Ile Asp His Leu Gln Ala Gln Leu Asp Lys Leu Arg 35 40 45 Arg Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala 50 55 60 Gln Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu 65 70 75 80 Thr Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr 85 90 95 Arg Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg 100 105 110 Leu Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser 115 120 125 Tyr Leu Gly Glu Asp Thr Ala Glu Gln Leu Glu Leu Met Arg Ser Ala 130 135 140 Phe Arg Val Ile Arg Thr Val Arg Glu Lys His Ala Cys Thr Gln Cys 145 150 155 160 Asp Ala Ile Val Gln Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly 165 170 175 Ile Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Ser Lys Tyr Ala 180 185 190 Glu His Thr Pro Leu Tyr Arg Gln Ser Glu Ile Tyr Gly Arg Gln Gly 195 200 205 Val Glu Leu Arg Arg Ser Leu Leu Ser Gly Trp Val Asp Ala Cys Cys 210 215 220 Arg Leu Leu Ser Pro Leu Glu Glu Ala Leu His Gly Tyr Val Met Thr 225 230 235 240 Asp Gly Lys Leu His Ala Asp Asp Thr Pro Val Gln Val Leu Leu Pro 245 250 255 Gly Asn Lys Lys Thr Lys Thr Gly Arg Leu Trp Ala Tyr Val Arg Asp 260 265 270 Asp Arg Asn Ala Gly Ser Ala Leu Ala Pro Ala Val Trp Phe Ala Tyr 275 280 285 Ser Pro Asp Arg Lys Gly Ile His Pro Gln Thr His Leu Ala Cys Phe 290 295 300 Ser Gly Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr 305 310 315 320 Arg Asn Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg 325 330 335 Lys Ile His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu 340 345 350 Ala Leu Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg 355 360 365 Gly Met Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys 370 375 380 Pro Leu Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr 385 390 395 400 Leu Ser Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn 405 410 415 Gln Trp Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile 420 425 430 Asp Asn Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg 435 440 445 Lys Asn Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala 450 455 460 Leu Leu Tyr Ser Leu Ile Gly Thr Cys Lys Leu Asn Asp Val Asp Pro 465 470 475 480 Glu Ser Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val 485 490 495 Asn Arg Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu 500 505 510 * <210> 73 <211> 141 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(50612..51034) <400> 73 Met Asp Glu Lys Gln Leu Gln Ala Leu Ala Asn Glu Leu Ala Lys Asn 1 5 10 15 Leu Lys Thr Pro Glu Asp Leu Ser Gln Phe Asp Arg Leu Leu Lys Lys 20 25 30 Ile Ser Val Glu Ala Ala Leu Asn Ala Glu Met Ser His His Leu Gly 35 40 45 Tyr Asp Lys Asn Gln Pro Lys Pro Gly Ala Asn Ser Arg Asn Gly Tyr 50 55 60 Ser Thr Lys Thr Val Ile Thr Gly Asp Gly His Leu Glu Leu Arg Thr 65 70 75 80 Pro Arg Asp Arg Asp Gly Ser Phe Glu Pro Gln Leu Val Lys Lys Asn 85 90 95 Gln Thr Arg Ile Thr Gly Met Asp Asn Gln Ile Leu Ser Leu Tyr Ala 100 105 110 Lys Gly Leu Thr Thr Arg Glu Ile Ala Ala Ala Phe Lys Glu Leu Tyr 115 120 125 Asp Ala Asp Val Val Ser Val Gln Arg Gly Pro Tyr * 130 135 140 <210> 74 <211> 124 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(51184..51555) <400> 74 Met Leu Gln Leu Ser Ser Asn Ile Gly Trp Lys Lys Gly Ala Glu Asn 1 5 10 15 Ala Leu Lys Asn Lys Ile His Ser His Ser Phe Val Val Asn Pro Asp 20 25 30 Glu Phe Ser Cys Asp Thr Gln Phe Leu Lys Cys Pro Ile Thr Leu Cys 35 40 45 Val Pro Glu Lys Gly Val Phe Val Lys Asn Ala Leu Asn Ser Asn Ile 50 55 60 Cys Thr Leu Tyr Asp Lys Ser Ala Phe Met Asn Leu Thr Arg Glu His 65 70 75 80 Leu Pro His Pro Leu Ser Arg Glu Lys Ile Val Lys Glu Met Ile Ile 85 90 95 Glu Arg Asn Met Cys Tyr Phe Asp Thr Ile Ser Gln His Phe Ile Ile 100 105 110 Met Asp Ala Asp Gln Gln Lys Gln His Cys Lys * 115 120 <210> 75 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(51819..52166) <400> 75 Val Asp Phe Ser Trp Glu Gly Arg Glu Leu Glu Phe Leu Ile Tyr Phe 1 5 10 15 Asn Cys Ile Asn Ile Leu Asn Gly Leu His Arg Val Asn Val Ser Ser 20 25 30 Thr Pro Tyr Ser Leu Ala Tyr Asn Thr Cys Cys Asn Leu His Leu Ser 35 40 45 Ala Met Lys Lys His His Leu Ser Leu Tyr Glu Ile Leu Asp Leu Pro 50 55 60 Ser Ala Asn Leu Ser Phe Gln Ser Thr Phe Lys Tyr Cys Ile Tyr Leu 65 70 75 80 Pro Thr Arg Ser Tyr Phe Arg Lys Leu Asn Met Asn Asp Asn Ile Pro 85 90 95 Thr Ala Arg Asn His Lys Gln Ser Thr Cys Ile Thr Glu Lys Thr Cys 100 105 110 Leu Tyr Phe * 115 <210> 76 <211> 49 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(52108..52254) <400> 76 Met Pro Gly Leu Val Ser Tyr Ile Ser Ser Thr Ser Phe Ala Asn Glu 1 5 10 15 Met Ala Glu Met Arg Gln Gln Val Met Glu Gly Gln Ile Gly Gly Phe 20 25 30 Leu Leu Gly Gly Glu Arg Val Arg Val Ser Tyr Leu Phe Gln Leu His 35 40 45 * <210> 77 <211> 170 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(52545..53054) <400> 77 Met Ala Ala Ser Gly Gly Gly Glu Ile Thr Val Gly Gly Gln Thr Val 1 5 10 15 Arg Ile Thr Tyr Ser Glu Thr Asp Gly Arg Phe Leu Ala Ser Gly Gly 20 25 30 Asn Asn Ser Leu Leu Ser Gly Leu Leu Leu Thr Gly Leu Asn Gly Gly 35 40 45 Pro Glu Ala Leu Arg Asp Ile Met Leu Arg Met Val Ser Gly Ser Gly 50 55 60 Asn Thr Gln Ser His Gly Asp Ile Glu Gly Lys Ile Ser Gln Cys Lys 65 70 75 80 Phe Ser Val Asn Thr Glu Ser Leu Gln Cys Pro Ser Glu Ala Val Arg 85 90 95 Cys Pro Ile Ile Leu Asp Lys Pro Glu Glu Gly Val Phe Val Lys Asn 100 105 110 Ser Glu Gly Ser Leu Val Cys Thr Leu Phe Asp Ser Val Ser Phe Ser 115 120 125 His Leu Val Arg Asp Gly Gly Lys His Pro Leu Thr Arg Glu Pro Ile 130 135 140 Thr Ser Ser Met Ile Val Ser Gln Glu Gln Cys Ile Tyr Asp Gln Thr 145 150 155 160 Lys Gly Asn Phe Val Ile Lys Asp Lys * 165 <210> 78 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(53234..53503) <400> 78 Met Asn Ile Leu Lys Lys Ile Met Gln Arg Leu Cys Gly Cys Gly Lys 1 5 10 15 His Asp Asp Arg Glu Asn Gly Glu Leu Leu Thr Ala Gln Leu Arg Leu 20 25 30 Gly Pro Ala Asp Ile Leu Glu Ser Asp Glu Asn Gly Ile Ile Pro Glu 35 40 45 Gln Asp Arg Val Ile Thr Gln Val Val Ile Leu Asp Ala Asp Lys Lys 50 55 60 Gln Ile Gln Cys Val Val Arg Pro Leu Gln Ile Leu Arg Ala Asp Gly 65 70 75 80 Thr Trp Glu Asn Ile Gly Gly Met Lys * 85 <210> 79 <211> 408 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(53505..54728) <400> 79 Met Ala Val Lys Ile Ser Gly Val Leu Lys Asp Gly Thr Gly Lys Pro 1 5 10 15 Val Glu Asn Cys Thr Ile Gln Leu Lys Ala Arg Arg Asn Ser Ala Thr 20 25 30 Val Val Val Asn Thr Val Ala Ser Glu Asn Pro Asp Glu Ala Gly Arg 35 40 45 Tyr Ser Met Asp Val Glu Tyr Gly Gln Tyr Ser Val Ile Leu Leu Val 50 55 60 Glu Gly Phe Pro Pro Ser His Ala Gly Thr Ile Thr Val Tyr Glu Asp 65 70 75 80 Ser Gln Pro Gly Thr Leu Asn Asp Phe Leu Gly Ala Met Ser Glu Asp 85 90 95 Asp Val Arg Pro Glu Ala Leu Arg Arg Phe Glu Leu Met Val Glu Glu 100 105 110 Ala Ala Arg His Ala Glu Glu Ala Lys Lys Asn Ala Gly Glu Ala Glu 115 120 125 Thr Ser Ala Arg Asn Ala Gly Ile Ser Ala Ser Gln Ala Glu Glu Ser 130 135 140 Ala Ala Asn Ala Asp Thr Ser Ala Gly Asp Ala Ser Glu Ser Ala Arg 145 150 155 160 Gln Ala Ala Glu Ser Ala Ala Ala Ala Lys Gln Ser Glu Glu Ala Ser 165 170 175 Ser Ser Ser Ala Ser Ala Ala Ala Gln Lys Ala Ser Glu Ser Ser Gln 180 185 190 Ser Ala Ala Asp Ala Glu Leu Ser Lys Lys Thr Ala Glu Ser Ala Ala 195 200 205 Gly Asn Ala Ala Arg Asp Ala Thr Thr Ala Thr Glu Lys Ala Arg Glu 210 215 220 Ser Ala Glu Ser Ala Gln Ser Ala Glu Gln Ser Arg Ile Ala Ala Glu 225 230 235 240 Glu Ala Val Asn Arg Ile Pro Thr Val Val Gly Pro Pro Gly Pro Lys 245 250 255 Gly Glu Pro Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp Lys Gly 260 265 270 Glu Arg Gly Asp Thr Gly Pro Ala Gly Ala Thr Gly Glu Arg Gly Pro 275 280 285 Ala Gly Asp Ala Gly Pro Ala Gly Pro Ala Gly Pro Ala Gly Pro Gln 290 295 300 Gly Pro Lys Gly Glu Thr Gly Ala Ala Gly Pro Val Gly Ala Thr Gly 305 310 315 320 Pro Gln Gly Pro Lys Gly Asp Pro Gly Glu Thr Gln Ile Arg Phe Arg 325 330 335 Leu Gly Pro Gly Asn Ile Ile Glu Thr Asn Ser His Gly Trp Phe Pro 340 345 350 Asp Thr Asp Gly Ala Leu Ile Thr Gly Leu Thr Phe Leu Asp Pro Lys 355 360 365 Asp Ala Thr Arg Val Gln Gly Phe Phe Gln His Leu Gln Val Arg Phe 370 375 380 Gly Asp Gly Pro Trp Gln Asp Val Lys Gly Leu Asp Glu Val Gly Ser 385 390 395 400 Asp Thr Gly Arg Thr Gly Glu * 405 <210> 80 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(54793..55392) <400> 80 Met Arg Lys Leu Tyr Ala Ala Ile Leu Ser Ala Ala Ile Cys Leu Ala 1 5 10 15 Val Ser Gly Ala Pro Ala Trp Ala Ser Glu Gln Gln Ala Thr Leu Ser 20 25 30 Ala Gly Tyr Leu His Ala Arg Thr Ser Ala Pro Gly Ser Asp Asn Leu 35 40 45 Asn Gly Ile Asn Val Lys Tyr Arg Tyr Glu Phe Thr Asp Thr Leu Gly 50 55 60 Leu Val Thr Ser Phe Ser Tyr Ala Gly Asp Lys Asn Arg Gln Leu Thr 65 70 75 80 Arg Tyr Ser Asp Thr Arg Trp His Glu Asp Ser Val Arg Asn Arg Trp 85 90 95 Phe Ser Val Met Ala Gly Pro Ser Val Arg Val Asn Glu Trp Phe Ser 100 105 110 Ala Tyr Ala Met Ala Gly Val Ala Tyr Ser Arg Val Ser Thr Phe Ser 115 120 125 Gly Asp Tyr Leu Arg Val Thr Asp Asn Lys Gly Lys Thr His Asp Val 130 135 140 Leu Thr Gly Ser Asp Asp Gly Arg His Ser Asn Thr Ser Leu Ala Trp 145 150 155 160 Gly Ala Gly Val Gln Phe Asn Pro Thr Glu Ser Val Ala Ile Asp Ile 165 170 175 Ala Tyr Glu Gly Ser Gly Ser Gly Asp Trp Arg Thr Asp Gly Phe Ile 180 185 190 Val Gly Val Gly Tyr Lys Phe * 195 <210> 81 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(55460..55675) <400> 81 Val Arg Lys Asn Gly Ala Glu Ile Tyr Asn Arg Thr Ala Leu Asp Asn 1 5 10 15 Thr Leu Ile Tyr Ser Gly Val Ile Asp Met Pro Ala Gly His Gly His 20 25 30 Met Thr Leu Glu Phe Ser Val Ser Ala Trp Leu Val Asn Asn Trp Tyr 35 40 45 Pro Thr Ala Ser Ile Ser Asp Leu Leu Val Val Val Met Lys Lys Ala 50 55 60 Thr Ala Gly Ile Ser Ile Ser * 65 70 <210> 82 <211> 654 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(55678..57639) <400> 82 Met Asp Ala Phe Gly Cys Thr Ser Arg Gly Gln Ala His Arg Ala Gly 1 5 10 15 Leu Trp Val Ile Lys Thr Gly Leu Leu Glu Thr Gln Thr Val Asp Phe 20 25 30 Thr Leu Gly Ser Gln Gly Leu Arg His Thr Pro Gly Asp Ile Ile Glu 35 40 45 Ile Cys Asp Asn Asp Tyr Ala Gly Thr Met Thr Gly Gly Arg Val Leu 50 55 60 Ser Ile Asp Ala Ala Ser Arg Thr Leu Thr Leu Asp Arg Glu Val Thr 65 70 75 80 Leu Pro Glu Thr Gly Ala Ala Thr Val Asn Leu Ile Asn Gly Ser Gly 85 90 95 Lys Pro Val Ser Val Asp Ile Thr Ala His Pro Ala Pro Asp Arg Ile 100 105 110 Gln Val Ser Thr Leu Pro Asp Gly Val Glu Thr Tyr Gly Val Trp Gly 115 120 125 Leu Ser Leu Pro Ser Leu Cys Arg Arg Leu Phe Arg Cys Val Ser Val 130 135 140 Arg Glu Asn Thr Asp Gly Thr Phe Ala Ile Thr Ala Val Gln His Val 145 150 155 160 Pro Glu Lys Glu Ala Ile Val Asp Asn Gly Ala Arg Phe Glu Pro Gln 165 170 175 Ser Gly Ser Leu Asn Ser Val Ile Pro Pro Ala Val Gln His Leu Thr 180 185 190 Val Glu Val Ser Ala Ala Asp Gly Gln Tyr Leu Ala Gln Ala Lys Trp 195 200 205 Asp Thr Pro Arg Val Val Lys Gly Val Arg Phe Ser Leu Arg Leu Thr 210 215 220 Ser Gly Lys Gly Thr Asp Ala Arg Leu Val Thr Thr Ala Ile Thr Ala 225 230 235 240 Asp Thr Glu His Arg Phe Ser Gly Leu Pro Leu Gly Glu Tyr Thr Leu 245 250 255 Thr Val Arg Ala Ile Asn Ser Tyr Gly Gln Gln Gly Glu Pro Ala Thr 260 265 270 Thr Thr Phe Arg Ile Ala Ala Pro Ala Ala Pro Ser Arg Ile Glu Leu 275 280 285 Thr Pro Gly Tyr Phe Gln Ile Thr Ala Thr Pro His Leu Ala Val Tyr 290 295 300 Asp Pro Thr Val Gln Phe Glu Phe Trp Phe Ser Glu Lys Arg Ile Ala 305 310 315 320 Asp Ile Arg Gln Val Glu Thr Ala Ala Arg Tyr Leu Gly Ser Ala Leu 325 330 335 Tyr Trp Ile Ala Ala Ser Ile Asn Ile Lys Pro Gly His Asp Tyr Tyr 340 345 350 Phe Tyr Ile Arg Ser Val Asn Thr Val Gly Lys Ser Ala Phe Val Glu 355 360 365 Ala Val Gly Arg Ala Ser Asp Asp Ala Glu Gly Tyr Leu Asp Phe Phe 370 375 380 Lys Gly Glu Ile Gly Lys Thr His Leu Ala Gln Glu Leu Trp Thr Gln 385 390 395 400 Ile Asp Asn Gly Gln Leu Ala Pro Asp Leu Ala Glu Ile Arg Thr Ser 405 410 415 Ile Thr Asn Val Ser Asn Glu Ile Thr Gln Thr Val Asn Lys Lys Leu 420 425 430 Glu Asn Gln Ser Ala Ala Ile Gln Gln Ile Gln Lys Val Gln Val Asp 435 440 445 Thr Asn Asn Asn Leu Asn Ser Met Trp Ala Val Lys Leu Gln Gln Met 450 455 460 Gln Asp Gly Arg Leu Tyr Ile Ala Gly Ile Gly Ala Gly Ile Glu Asn 465 470 475 480 Thr Pro Ala Gly Met Gln Ser Gln Val Leu Leu Ala Ala Asp Arg Ile 485 490 495 Ala Met Ile Asn Pro Ala Asn Gly Asn Thr Lys Pro Met Phe Val Gly 500 505 510 Gln Gly Asp Gln Ile Phe Met Asn Glu Val Phe Leu Lys Tyr Leu Thr 515 520 525 Ala Pro Thr Ile Thr Ser Gly Gly Asn Pro Pro Ala Phe Ser Leu Thr 530 535 540 Ser Asp Gly Lys Leu Thr Ala Lys Asn Ala Asp Ile Ser Gly Ser Val 545 550 555 560 Asn Ala Asn Ser Gly Thr Leu Asn Asn Val Thr Ile Asn Glu Asn Cys 565 570 575 Arg Val Leu Gly Lys Leu Ser Ala Asn Gln Ile Glu Gly Asp Leu Val 580 585 590 Lys Thr Val Gly Lys Ala Phe Pro Arg Asp Ser Arg Ala Pro Glu Arg 595 600 605 Trp Pro Ser Gly Thr Ile Thr Val Arg Val Tyr Asp Asp Gln Pro Phe 610 615 620 Asp Arg Gln Ile Val Ile Pro Ala Val Ala Phe Ser Gly Ala Lys His 625 630 635 640 Glu Arg Glu Ser Ile Leu Ile Phe Thr Pro His Ala Val * 645 650 <210> 83 <211> 392 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(57759..58934) <400> 83 Met Gly Lys Gly Gly Gly Lys Ala His Thr Pro Arg Glu Ala Lys Asp 1 5 10 15 Asn Leu Lys Ser Thr Gln Met Met Ser Val Ile Asp Ala Ile Gly Glu 20 25 30 Gly Pro Ile Glu Gly Pro Val Lys Gly Leu Gln Ser Ile Leu Val Asn 35 40 45 Lys Thr Pro Leu Thr Asp Thr Asp Gly Asn Pro Val Ile His Gly Val 50 55 60 Thr Ala Val Trp Arg Ala Gly Glu Gln Glu Gln Thr Pro Pro Glu Gly 65 70 75 80 Phe Glu Ser Ser Gly Ala Glu Thr Gly Leu Gly Val Glu Val Thr Lys 85 90 95 Ala Lys Pro Val Thr Arg Thr Ile Thr Ser Ala Asn Ile Asp Arg Leu 100 105 110 Arg Val Thr Phe Gly Val Gln Ser Leu Leu Glu Thr Thr Ser Lys Gly 115 120 125 Asp Arg Asn His Ser Ser Val Arg Leu Leu Ile Gln Leu Gln Arg Asn 130 135 140 Gly Asn Trp Val Thr Glu Lys Asp Val Thr Ile Asn Gly Lys Thr Thr 145 150 155 160 Ser Gln Phe Leu Ala Ser Val Ile Leu Asp Asn Leu Pro Glu Arg Pro 165 170 175 Phe Asn Ile Arg Met Val Arg Glu Thr Ala Asp Ser Thr Ser Asp Gln 180 185 190 Leu Gln Asn Lys Thr Leu Trp Ser Ser Tyr Thr Glu Ile Ile Asp Val 195 200 205 Lys Gln Cys Tyr Pro Asn Thr Ala Ile Val Gly Leu Gln Val Asp Ala 210 215 220 Glu Gln Phe Gly Gly Gln Gln Met Thr Val Asn Tyr His Ile Arg Gly 225 230 235 240 Arg Ile Ile Gln Val Pro Ser Asn Tyr Asp Pro Glu Lys Arg Thr Tyr 245 250 255 Ser Gly Ile Trp Asp Gly Ser Leu Lys Pro Ala Tyr Ser Asn Asn Pro 260 265 270 Ala Trp Cys Leu Trp Asp Met Leu Thr His Pro Arg Tyr Gly Met Gly 275 280 285 Lys Arg Leu Gly Ala Ala Asp Val Asp Lys Trp Ala Leu Tyr Ala Ile 290 295 300 Ala Gln Tyr Cys Asp Gln Thr Val Pro Asp Gly Phe Gly Gly Thr Glu 305 310 315 320 Pro Arg Met Thr Phe Asn Ala Tyr Leu Ser Gln Gln Arg Lys Ala Trp 325 330 335 Asp Val Leu Ser Asp Phe Cys Ser Ala Met Arg Cys Met Pro Val Trp 340 345 350 Asn Gly Gln Thr Leu Thr Phe Val Gln Asp Arg Pro Ser Asp Val Val 355 360 365 Trp Pro Thr Pro Ala Val Met Trp Trp Trp Met Ile Thr Ala Trp Gly 370 375 380 Phe Ala Thr Ala Ser Ala Pro * 385 390 <210> 84 <211> 227 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(59276..59956) <400> 84 Met Ala Thr Thr Asn Ala Phe Ser Leu Ala Ser Pro Pro Leu Ala Arg 1 5 10 15 Ile Cys Leu His Gly Asp Leu Gln Arg Phe Gly Arg Arg Leu Ser Leu 20 25 30 Tyr Val Asn Thr Ala Ala Glu Ala Ile Arg Ala Leu Ser Leu Gln Val 35 40 45 Pro Gly Phe Arg Arg Gln Met Asn Glu Gly Trp Tyr Gln Ile Arg Ile 50 55 60 Ala Gly Tyr Asp Thr Ala Pro Glu Ala Val Tyr Ala Arg Leu His Glu 65 70 75 80 Gln Leu Gly Glu Gly Thr Val Ile His Ile Val Pro Arg Leu Ala Gly 85 90 95 Ala Gly Lys Gly Gly Leu Gln Ile Val Leu Gly Ala Ala Ala Ile Val 100 105 110 Gly Ser Phe Phe Thr Ala Gly Ala Ser Met Ala Leu Trp Gly Ser Ala 115 120 125 Leu Ala Ala Gly Gly Phe Ser Ala Thr Thr Met Leu Phe Ser Leu Gly 130 135 140 Ala Ser Met Ile Leu Gly Gly Val Ala Gln Met Leu Ala Pro Lys Ala 145 150 155 160 Lys Thr Pro Asp Tyr Arg Ala Thr Asp Asn Gly Arg Gln Asn Thr Tyr 165 170 175 Phe Ser Ser Leu Asp Asn Met Ile Ala Gln Gly Asn Pro Met Pro Val 180 185 190 Pro Tyr Gly Glu Met Leu Val Gly Ser Arg Arg Ile Ser Gln Asp Ile 195 200 205 Ser Thr Arg Asp Glu Gly Gly Gly Gly Thr Val Val Val Val Gly Arg 210 215 220 Gln Gly * 225 <210> 85 <211> 225 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(59854..60528) <400> 85 Val Ile Ser Thr Pro Glu Gly Glu Trp Tyr Ile Pro Cys Val Asn Ile 1 5 10 15 Ser Ala Glu Pro Glu Ala Tyr Phe Arg Ile Ala Pro Glu Asp Trp Leu 20 25 30 Arg Ala Glu Met Gln Gly Glu Ile Val Ala Leu Val His Ser His Pro 35 40 45 Gly Gly Leu Pro Trp Leu Ser Glu Ala Asp Arg Arg Leu Gln Ile Lys 50 55 60 Ser Ala Leu Pro Trp Trp Leu Val Cys Arg Gly Asp Ile His Lys Phe 65 70 75 80 Arg Cys Val Pro His Leu Thr Gly Arg Arg Phe Glu His Gly Val Thr 85 90 95 Asp Cys Tyr Thr Leu Phe Arg Asp Ala Tyr His Leu Ala Gly Thr Asp 100 105 110 Met Pro Asp Phe Glu Arg Glu Asp Asp Trp Trp Arg Asn Gly Gln Asn 115 120 125 Leu Tyr Leu Asp Asn Met Glu Ala Thr Gly Phe Tyr Arg Ile Ser Leu 130 135 140 Pro Ser Ala Gln Pro Gly Asp Ile Leu Leu Cys Cys Phe Gly Ala Ser 145 150 155 160 Val Ala Asn His Ala Ala Ile Tyr Cys Gly Asn Gly Glu Leu Leu His 165 170 175 His Leu Pro Glu Gln Leu Ser Lys Arg Glu Arg Tyr Ser Glu Lys Trp 180 185 190 Gln Arg Arg Thr His Ser Ala Trp Arg His Arg His Trp His Val Ser 195 200 205 Ala Phe Thr Gly Ile Tyr Asn Asp Leu Ala Ala Ala Ser Ala Cys Met 210 215 220 * <210> 86 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(60608..61306) <400> 86 Met Gln Asn Ile His Glu Glu Ser Leu Asn Glu Ser Val Lys Ser Glu 1 5 10 15 Gln Ser Pro Arg Val Val Leu Trp Glu Ile Asp Leu Thr Val Gln Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Leu Asn Glu Lys Gly Glu Ala 35 40 45 Val Thr Trp Gln Gly Arg Gln Tyr Gln Val Tyr Pro Ile Asp Gly Ser 50 55 60 Gly Phe Glu Met Asn Gly Lys Gly Ser Ser Ala Arg Pro Ser Leu Thr 65 70 75 80 Val Ser Asn Leu Phe Gly Leu Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Ala Thr Val Val Arg Arg Arg Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Ala Gly Asn Pro Glu Ala Asp Pro Glu 115 120 125 Gln Glu Leu Arg Asp Arg Trp Val Val Glu Gln Met Ser Glu Leu Thr 130 135 140 Ala Met Thr Ala Ser Phe Val Leu Ala Thr Pro Thr Glu Thr Asp Gly 145 150 155 160 Ala Leu Phe Pro Gly Arg Ile Met Leu Ala Asn Thr Cys Met Trp Thr 165 170 175 Tyr Arg Ser Asp Glu Cys Gly Tyr Thr Gly Gly Ala Val Ala Asp Glu 180 185 190 Phe Asp Asn Pro Thr Thr Asp Ile Arg Lys Asp Arg Cys Ser Lys Cys 195 200 205 Met Arg Gly Cys Glu Met Arg Ser Met Val Ala Asn Phe Gly Gly Phe 210 215 220 Leu Ser Ile Asn Lys Leu Ser Gln * 225 230 <210> 87 <211> 114 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(61306..61647) <400> 87 Val Ala Glu Ile Lys Thr Leu His Leu Val Pro Arg Glu Gly Met Gln 1 5 10 15 Val Ser Glu Lys Pro Ser Val Val Arg Val Arg Phe Gly Asp Gly Tyr 20 25 30 Glu Gln Arg Arg Pro Thr Gly Leu Asn Pro Gln Leu Lys Thr Phe Gln 35 40 45 Ala Val Phe Arg Val Thr Asp Glu Ser Thr Arg Arg Trp Leu Asp Glu 50 55 60 Phe Leu Ser Trp His Gly Gly Tyr Arg Ala Phe Leu Trp Arg Pro Pro 65 70 75 80 Lys His Asn Arg Thr Val Arg Val Val Cys Arg Glu Trp Ser Val Thr 85 90 95 Asp Asn Ala Arg Tyr Ser Asp Phe Ser Cys Thr Ile Glu Gln Val Val 100 105 110 Asn * <210> 88 <211> 1081 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(61640..64882) <400> 88 Met Ala Thr Leu Arg Glu Leu Ile Ile Lys Ile Ser Ala Asn Ser Gln 1 5 10 15 Ser Phe Gln Ser Glu Ile Gln Arg Ala Ser Arg Met Gly Ser Glu Tyr 20 25 30 Tyr Arg Thr Leu Gln Asn Gly Gly Arg Gln Ala Ala Ala Ala Ala Arg 35 40 45 Glu Gln Arg Arg Ala Leu Ala Glu Leu His Ser Gln Leu Thr Glu Ile 50 55 60 Arg Ala Ser Ala Val Gly Met Thr Gly Ala Phe Ala Gly Ala Phe Ala 65 70 75 80 Thr Gly His Leu Ile Ser Leu Ala Asp Glu Trp Ser Ser Val Asn Ala 85 90 95 Arg Leu Lys Gln Ala Ser Gln Ser Ser Asp Glu Phe Ala Ser Ser Gln 100 105 110 Lys Val Leu Met Asp Ile Ser Gln Arg Thr Gly Thr Ala Phe Ser Asp 115 120 125 Asn Ala Ala Leu Phe Ala Arg Ser Ala Ala Ser Met Arg Glu Tyr Gly 130 135 140 Tyr Ser Ala Asp Asp Val Leu Lys Val Thr Glu Ala Ile Ser Thr Gly 145 150 155 160 Leu Lys Ile Ser Gly Ala Ser Thr Ala Glu Ala Gly Ser Val Ile Thr 165 170 175 Gln Phe Ser Gln Ala Leu Ala Gln Gly Val Leu Arg Gly Glu Glu Phe 180 185 190 Asn Ser Val Asn Glu Ser Gly Asp Arg Ile Val Arg Ala Leu Ala Ala 195 200 205 Gly Met Gly Val Ala Arg Lys Asp Leu Lys Ala Met Ala Asp Asp Gly 210 215 220 Lys Leu Thr Ala Asp Lys Val Val Pro Ala Leu Ile Ser Gln Leu Gly 225 230 235 240 Ile Leu Arg Asp Glu Tyr Ala Ala Met Pro Glu Thr Val Ser Ser Ser 245 250 255 Ile Thr Lys Val Glu Asn Ala Phe Met Ala Trp Val Gly Gly Ala Asn 260 265 270 Glu Ala Ser Gly Val Thr Lys Thr Leu Ser Gly Met Leu Asn Gly Val 275 280 285 Ala Gly Gln Ile Asp Asn Val Ala Thr Ala Val Gly Ala Leu Val Ala 290 295 300 Val Gly Val Ala Arg Tyr Phe Gly Asn Met Ala Ser Gly Ala Met Ser 305 310 315 320 Ala Thr Ala Gly Leu Val Thr Ala Ala Arg Asn Glu Val Ala Leu Ala 325 330 335 Glu Ala Gln Phe Arg Gly Thr Gln Ile Ala Thr Ala Arg Ala Arg Ala 340 345 350 Ala Val Tyr Arg Ala Gln Gln Ala Val Ala Ala Ala Arg Gly Thr Glu 355 360 365 Met Gln Ile Ala Ala Glu Ala Arg Leu Ala Ala Thr Gln Glu Arg Leu 370 375 380 Asn Arg Asn Ile Ala Ala Arg Ser Ala Ala Gln Asn Ala Leu Asn Ser 385 390 395 400 Thr Thr Ala Val Gly Ser Arg Leu Met Ser Gly Ala Leu Gly Leu Val 405 410 415 Gly Gly Val Pro Gly Leu Val Met Leu Gly Ala Ala Ala Trp Tyr Thr 420 425 430 Leu Tyr Gln Asn Gln Glu Gln Ala Arg Glu Ser Ala Arg Gln Tyr Ala 435 440 445 Leu Thr Ile Asp Glu Ile Ala His Lys Thr Pro Ser Met Ser Leu Pro 450 455 460 Glu Ala Ser Asp Asn Glu Gly Arg Thr Arg Ala Ala Leu Thr Glu Gln 465 470 475 480 Asn Arg Leu Ile Asp Glu Gln Ala Ser Arg Val Lys Ser Leu Gln Glu 485 490 495 Lys Ile Ala Gly Tyr Gln Tyr Val Leu Ala Asn Pro Gly Trp Thr Thr 500 505 510 Gly Asp Gly Phe Met Ile Asn His Leu Thr Ser Val Lys Thr Val Thr 515 520 525 Glu Gly Leu Ala Gln Ala Thr Glu Gln Leu Ala Val Glu Gln Ser Arg 530 535 540 Leu Ala Gln Met Gln Glu Lys Ala Gln Ser Ile Gln Asp Val Leu Ala 545 550 555 560 Gly Leu Glu Asp Arg Arg Val Ala Leu Ile Arg Gln Gln Ala Ala Glu 565 570 575 Gln Asn Lys Val Tyr Gln Ser Met Leu Val Met Asn Gly Gln Tyr Thr 580 585 590 Glu Phe Asn Arg Leu Leu Gly Leu Gly Asn Glu Leu Leu Gln Gln Arg 595 600 605 Gln Gly Leu Val Asn Val Pro Leu Arg Leu Pro Gln Ala Thr Leu Asp 610 615 620 Asp Lys Gln Gln Ser Ala Leu Thr Lys Thr Glu Arg Glu Leu Ala Leu 625 630 635 640 Ser Arg Leu Lys Gly Glu Glu Lys Glu Arg Val Arg Leu Gly Tyr Ala 645 650 655 Ala Asp Asp Leu Gly Phe Val Gly Asp Pro Tyr Gln Glu Ala Arg Gln 660 665 670 Arg Tyr Ile Ser Asn Ala Leu Glu Ala Trp Arg Asn Asn Glu Val Asn 675 680 685 Lys Pro Lys Ser Arg Gly Gly Lys Ser Glu Thr Glu Lys Ala Glu Asp 690 695 700 Ser Phe Ser Arg Leu Leu Lys Gln Gln Lys Glu Gln Leu Ala Leu Ala 705 710 715 720 Gly Gln Asn Thr Glu Leu Ala Lys Leu Lys Tyr Gln Thr Ala Leu Gly 725 730 735 Glu Leu Lys Thr Leu Ser Glu Ile Gln Lys Gln Glu Leu Leu Arg Asn 740 745 750 Ala Ala Leu Ile Asp Gln Gln Lys Ile Arg Glu Gln Leu Arg Tyr Arg 755 760 765 Glu Glu Thr Leu Lys Asn Asp Asn Val Ala Ala Arg Ala Ser Asn Glu 770 775 780 Ser Glu Leu Leu Gly Tyr Gly Gln Gly Glu Arg Ala Arg Glu Arg Met 785 790 795 800 Arg Glu Leu Gln Gln Ile Arg Asp Ser Phe Arg Gln Lys Asp Ala Asp 805 810 815 Leu Gln Ser Gln Tyr Gln Thr Gly Asp Ile Ser Glu Asp Phe Tyr Arg 820 825 830 Gln Ala Leu Ala Gln Asn Ala Gln Tyr Leu Ser Glu Arg Leu Lys Asp 835 840 845 Gln Ala Val Phe Tyr Ala Glu Ser Asp Val Gln Arg Ala Asp Trp Gln 850 855 860 Lys Gly Leu Gln Glu Gly Phe Ser Asn Trp Val Asp Asn Ala Ser Asp 865 870 875 880 Tyr Ala Ser Gln Ala Ala Gln Leu Ala Thr Glu Gly Ile Ser Gly Met 885 890 895 Val Asn Asn Ile Thr Glu Met Leu Asn Gly Asn Lys Val Glu Trp Arg 900 905 910 Ser Trp Ala Ser Ser Val Leu Gln Glu Ile Ser Lys Val Leu Met Asn 915 920 925 Ala Ala Ile Val Asn Gly Ile Lys Thr Ala Ala Asn Gly Met Ser Gly 930 935 940 Ala Gly Gly Phe Leu Gly Ser Ile Gly Asp Trp Leu Gly Gly Ala Val 945 950 955 960 Ala Asn Ala Lys Gly Gly Val Tyr Thr Ser Ala Asn Leu Ser Ala Tyr 965 970 975 Ser Asn Ser Ile Val Asp Thr Pro Thr Tyr Phe Ala Phe Ala Lys Gly 980 985 990 Ala Gly Leu Met Gly Glu Ala Gly Pro Glu Ala Ile Met Pro Leu Thr 995 1000 1005 Arg Ala Ala Asp Gly Ser Leu Gly Val Arg Ala Val Gly Ser Met Asn 1010 1015 1020 Gly Ser Ala Gly Leu Val Tyr Ser Pro Val Tyr His Ile Ala Ile Gln 1025 1030 1035 1040 Asn Asp Gly Ala Asn Gly Gln Ile Gly Pro Glu Ala Ala Gly Ser Leu 1045 1050 1055 Val Gln Leu Ile Asp Gln Arg Val Gln Ala Val Met Leu Ser Met Arg 1060 1065 1070 Arg Asp Gly Gly Met Leu Ser Gly * 1075 1080 <210> 89 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(64930..65211) <400> 89 Met Arg Leu Ala Leu Arg Leu Gly Arg Thr Leu Ser Glu Leu Arg His 1 5 10 15 Ser Leu Ser Ala Ser Glu Ala Met Met Trp Met Glu Phe Asp Arg Ile 20 25 30 Ser Pro Leu Gly Asp Glu Arg Gly Asp Ile Arg Asn Ala Gln Ile Val 35 40 45 Lys Ala Val Phe Gly Ala Gln Gly Met Asn Val Ala Leu Lys Asp Ala 50 55 60 Met Leu Cys Trp Gly Glu Asp Glu Asp Lys Pro Glu Val Asp Pro Phe 65 70 75 80 Ala Ala Leu Glu Asp Ala Leu Ser Leu Ala Ala Gln Ser * 85 90 <210> 90 <211> 125 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(65235..65609) <400> 90 Met Lys Lys Asp Leu Lys Thr Leu Ala Leu Ala Arg Leu Ser Gly Phe 1 5 10 15 Arg His Lys Thr Val Lys Val Pro Glu Trp Gly Asn Val Ser Val Val 20 25 30 Leu Arg Glu Pro Ser Ala Glu Ala Trp Tyr Leu Trp Gln Glu Val Leu 35 40 45 Asn Gly Asp Gly Glu Asp Asp Asp Thr Leu Ser Val Val Ala Lys Thr 50 55 60 Arg Arg Asn Leu Glu Ala Asp Val Thr Leu Phe Cys Asp Val Leu Cys 65 70 75 80 Asp Thr Asp Leu Gln Arg Val Phe Thr Pro Asp Asp Arg Glu Gln Val 85 90 95 Leu Ala Val Tyr Gly Pro Val His Ala Arg Leu Leu Arg Gln Ala Leu 100 105 110 Glu Leu Ile Ala Asp Ala Glu Ser Ala Arg Lys Lys * 115 120 <210> 91 <211> 239 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(65624..66340) <400> 91 Met Ser Ala Leu Tyr Glu Arg Ser Gln Leu Thr Gln Val Met Ile Ser 1 5 10 15 Ser Ala Pro Ala Thr Ala Glu Thr Met Asp Lys Ala Glu Tyr Leu Arg 20 25 30 Leu Asp Cys Thr Ile Lys Glu Val Gln Phe Thr Ala Gly Gln Lys Gln 35 40 45 Asp Ile Asp Val Thr Thr Leu Cys Ser Thr Glu Gln Glu Asn Ile Asn 50 55 60 Gly Leu Gly Ala Ser Ser Glu Ile Ser Met Ser Gly Asn Phe Tyr Leu 65 70 75 80 Asn Gln Ala Gln Asn Ala Leu Arg Asp Ala Tyr Asp Asn Asp Ala Leu 85 90 95 Tyr Ala Phe Lys Val Leu Phe Pro Ser Gly Lys Gly Phe Lys Phe Leu 100 105 110 Ala Glu Val Arg Gln His Thr Trp Ser Ser Gly Thr Asn Gly Val Val 115 120 125 Ala Ala Thr Phe Ser Leu Arg Leu Lys Gly Lys Pro Val Ser Phe Val 130 135 140 Val Pro Leu Ala Phe Val Lys Asn Leu Asp Lys Thr Leu Thr Val Asn 145 150 155 160 Thr Gly Ala Leu Leu Thr Met Ser Val Ser Ala Asn Gly Gly Thr Pro 165 170 175 Pro Tyr Lys Tyr Ala Trp Lys Lys Asp Gly Gln Pro Val Asp Gly Gln 180 185 190 Thr Thr Asp Thr Phe Ser Lys Pro Gly Ala Gln Ser Ala Asp Ala Gly 195 200 205 Lys Tyr Thr Cys Val Val Thr Asp Ser Ala Glu Lys Ala Gln Ser Val 210 215 220 Thr Ser Val Glu Cys Thr Val Thr Val Ser Ala Ala Ala Gly * 225 230 235 <210> 92 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(66406..66750) <400> 92 Met Thr Glu Ala Asp Leu Tyr Pro His Leu Ala His Leu Ala Gly Gly 1 5 10 15 Gln Val Tyr Pro Tyr Val Val Pro Leu Leu Asp Gly Arg Pro Ser Val 20 25 30 Ala Leu Pro Trp Val Val Phe Ser Leu Ile Ser Ser Val Ser Ala Asp 35 40 45 Val Met Gly Gly Gln Ala Glu Ser Ser Val Ser Val Gln Ile Asp Val 50 55 60 Tyr Ala Gly Thr Val Thr Gln Ala Arg Gln Ile Arg Gln Asp Ala Arg 65 70 75 80 Glu Ala Ile Met Leu Leu Ala Pro Gly Ser Val Ser Glu Met Gln Asp 85 90 95 Tyr Ile Pro Glu Asn Arg Cys Tyr Arg Ala Thr Leu Glu Phe Gln Val 100 105 110 Thr Val * <210> 93 <211> 149 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(66747..67193) <400> 93 Met Ile Glu Thr Leu Leu Asp Phe Ser Gly Leu Glu Asp Ile Ser Arg 1 5 10 15 Asp Leu Gln Leu Leu Ser Gly Ala Glu Asn Asn Arg Val Leu Arg Glu 20 25 30 Ala Thr Arg Ala Gly Ala Asn Val Leu Lys Glu Glu Val Val Ser Arg 35 40 45 Ala Pro Val Arg Arg Gly Lys Leu Arg Arg Asn Val Val Val Leu Ser 50 55 60 Arg Arg Ser Arg Asp Gly Gly Met Glu Ser Gly Val His Ile Arg Gly 65 70 75 80 Val Asn Pro Asp Thr Gly Asn Ser Asp Asn Thr Met Lys Ala Asp Asn 85 90 95 Pro Arg Asn Ala Phe Tyr Trp Arg Phe Val Glu Met Gly Thr Val Asn 100 105 110 Met Pro Pro His Pro Phe Val Arg Pro Ala Phe Asp Val Arg Ser Glu 115 120 125 Gln Ala Ala Gln Val Ala Ile Ala Arg Met Asn Arg Ala Ile Asp Glu 130 135 140 Val Leu Arg Arg * 145 <210> 94 <211> 117 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(67190..67540) <400> 94 Met Ala Ile Ser Ala Gly Arg Leu Thr Gln Met Ile Ser Val Leu Asn 1 5 10 15 Pro Val Leu Thr Arg Asn Ala Ala Gly Glu Met Thr Glu Glu Trp Val 20 25 30 Ser Cys Gly Lys Ile His Ala Asp Ile Arg Gly Arg Ser Ser Arg Glu 35 40 45 Arg Met Gln Ser Gly Ala Glu Met Ala Gln Ala Glu Ile Arg Ile Trp 50 55 60 Val Arg Gly Gln Ser Gly Arg Glu Ile Thr Ala Ala Ser Arg Leu His 65 70 75 80 Val Leu Ser Gly Pro Trp Arg Asp Arg Ile Leu Asn Val Val Gly Leu 85 90 95 Pro Val Pro Asp Ala Thr Gly Gly Arg Leu Glu Ile Leu Cys Arg Leu 100 105 110 Gly Gly Glu Lys * 115 <210> 95 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(67550..67876) <400> 95 Met Thr Ala Leu Leu Thr Leu Glu Glu Ile Lys Ala His Leu Arg Val 1 5 10 15 Asp His Asp Ala Asp Asp Asp Met Leu Met Asp Lys Val Arg Gln Ala 20 25 30 Thr Ala Val Leu Leu Ala Tyr Ile Gln Gly Ser Arg Asp Lys Val Ile 35 40 45 Arg Glu Asp Gly Glu Leu Ile Pro Gly Glu Ala Leu Thr Arg Met Lys 50 55 60 Gly Ala Ala Met Arg Leu Thr Gly Met Leu Tyr Arg Asn Pro Asp Leu 65 70 75 80 Ala Glu Arg Glu Glu Leu Ile Gln Gly Glu Leu Pro Phe Ser Val Ser 85 90 95 Val Leu Ile Tyr Asp Leu Arg Cys Pro Thr Val Leu * 100 105 <210> 96 <211> 860 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(67879..70458) <400> 96 Met Trp Asn Leu Leu Arg Arg Thr Arg Lys Asn Gln Lys Ser Gly Arg 1 5 10 15 Asp Val Arg Glu Val Gly Trp Arg Ser Leu Phe Gln Ala Val Ala Glu 20 25 30 Pro Phe Ala Gly Ala Trp Gln Gln Gly Val Lys Ala Asp Pro Glu Thr 35 40 45 Val Leu Ser Phe His Ala Val Phe Ser Cys Ile Ser Leu Ile Ser Gln 50 55 60 Asp Ile Ala Lys Met Arg Leu Arg Leu Met Gln Thr Asp Val Gln Gly 65 70 75 80 Ile Arg Arg Glu Lys Arg Gln Gly Asp Thr Ala Arg Leu Cys Arg Arg 85 90 95 Pro Asn Ala Gln Gln Asn Arg Ile Gln Phe Phe Glu Leu Trp Leu Asn 100 105 110 Ser Lys Leu Arg His Gly Asn Thr Val Val Leu Lys Ile Arg Thr Pro 115 120 125 Arg Gly Gln Ile Lys Glu Leu Arg Ile Leu Asp Trp Asn Arg Val Glu 130 135 140 Pro Leu Val Ala Asp Asp Gly Glu Val Phe Tyr Arg Ile Thr Pro Asp 145 150 155 160 Arg Asn Cys Gly Ile Thr Glu Ser Val Thr Val Pro Ala Arg Glu Val 165 170 175 Ile His Asp Arg Phe Asn Cys Phe Phe His Pro Leu Val Gly Leu Pro 180 185 190 Pro Val Tyr Ala Ala Gly Leu Ala Ala Met Gln Gly His His Ile Gln 195 200 205 Ala Asn Ser Thr Tyr Phe Phe Arg Asn Gly Gly Arg Pro Ser Gly Val 210 215 220 Ile Glu Val Pro Gly Ser Ile Thr Glu Glu Asn Ala Lys Lys Leu Lys 225 230 235 240 Gly Asn Trp Asp Ser Gly Tyr Thr Gly Glu Asn Ala Gly Lys Thr Ala 245 250 255 Ile Leu Ser Asn Gly Ala Lys Tyr Ser Pro Thr Thr Phe Ser Pro Val 260 265 270 Asp Ala Gln Thr Val Glu Gln Leu Lys Met Thr Ala Glu Ile Val Cys 275 280 285 Ser Val Phe Arg Val Pro Ala Tyr Lys Ile Gly Val Gly His Pro Pro 290 295 300 Ser Ser Asp Asn Val Glu Ala Leu Glu Gln Gln Tyr Tyr Ser Gln Cys 305 310 315 320 Leu Gln Thr Leu Ile Glu Ser Ile Glu Leu Leu Leu Asp Glu Ala Leu 325 330 335 Glu Thr Gly Glu Asn Glu Ser Thr Glu Phe Asp Val Thr Thr Leu Leu 340 345 350 Arg Met Asp Ser Glu Arg Arg Met Lys Thr Leu Gly Asp Ala Val Lys 355 360 365 Asn Thr Leu Leu Thr Pro Asn Glu Ala Arg Lys Arg Glu Asn Leu Pro 370 375 380 Pro Leu Ala Gly Gly Asp Ala Leu Tyr Leu Gln Gln Gln Asn Tyr Ser 385 390 395 400 Leu Glu Ala Leu Ser Arg Arg Asp Ala Arg Glu Asp Pro Phe Ala Ser 405 410 415 Ala Gly Lys Thr Val Ser Ser Gln Leu Pro Asp Gly Ala Ser Asp Gly 420 425 430 Asn Lys Ala Ile Ser Glu Thr Glu His Asp Ala Val Lys Ala Met Phe 435 440 445 Arg Gly Asp Thr Glu Lys Met Thr Glu Arg Glu Leu Ser Ile Ile Arg 450 455 460 Ala Leu Gly Glu Glu Phe Ser Thr Val Leu Ala Asp Leu Gln Arg Thr 465 470 475 480 Phe Glu Gly Lys Met Ala Ser Gln Ala Gln Ala Phe Glu Glu Lys Leu 485 490 495 Thr Ser Leu Ser Ala Val Leu Gln Lys His Val Thr Val Asp Glu Val 500 505 510 Arg Pro Val Leu Gln Ala Met Val Asp Asp Ala Val Gly Ala Ile Pro 515 520 525 Val Pro Arg Asp Gly Arg Asp Tyr Asp Pro Asp Val Leu Gln Gln Ala 530 535 540 Val Asn Asp Ala Val Ala Asn Ile Pro Gln Pro Ala Asp Gly Lys Ser 545 550 555 560 Leu Thr Pro Asp Asp Val Arg Pro Met Leu Glu Gln Met Val Lys Glu 565 570 575 Ala Val Ser His Ile Pro Val Pro Arg Asp Gly Arg Asp Tyr Asp Pro 580 585 590 Glu Val Leu Gln Lys Ala Val Asn Asp Ala Val Ala Asn Ile Pro Gln 595 600 605 Pro Ala Asp Gly Lys Ser Leu Thr Pro Asp Asp Val Arg Pro Met Leu 610 615 620 Glu Gln Met Val Lys Glu Ala Val Ser His Ile Pro Val Pro Arg Asp 625 630 635 640 Gly Arg Asp Tyr Asp Pro Glu Val Leu Gln Lys Ala Val Asn Asp Ala 645 650 655 Val Ala Asn Ile Pro Gln Pro Ala Asp Gly Lys Ser Leu Thr Pro Asp 660 665 670 Asp Val Arg Pro Met Leu Glu Gln Met Val Lys Glu Ala Val Ser His 675 680 685 Ile Pro Val Pro Arg Asp Gly Arg Asp Tyr Asp Pro Asp Val Leu Gln 690 695 700 Lys Ala Val Leu Asp Ala Val Ser Ala Leu Pro Ala Pro Gln Asp Gly 705 710 715 720 Arg Asp Ala Thr Ala Leu Glu Ile Leu Pro Ala Ile Asp Asp Gln Lys 725 730 735 Ser Phe Pro Arg Gly Thr Tyr Ala Thr His Gln Gly Gly Leu Trp Arg 740 745 750 Ala Tyr Glu Lys Thr His Gly Met Arg Gly Trp Glu Cys Leu Val Asp 755 760 765 Gly Val Ala Asp Ile Asp Val Ser Met Thr Gly Glu Arg Leu Phe Ser 770 775 780 Val Val Val Arg Gln Ser Ser Gly Gln Arg Thr Glu Lys Thr Phe Ser 785 790 795 800 Leu Pro Val Met Leu Tyr Arg Gly Val Phe Arg Ala Gly Glu Thr Tyr 805 810 815 His Pro Gly Asp Thr Val Thr Trp Gly Gly Ser Leu Trp His Cys Asn 820 825 830 Ser Met Thr Glu Asp Lys Pro Gly Glu Ala His Ser Ser Ala Trp Thr 835 840 845 Leu Ala Ala Lys Arg Gly Arg Asp Ala Gly Gly * 850 855 <210> 97 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(70409..70594) <400> 97 Met Met Pro Gly Pro Gly Ile Ser Val Met Trp His Ser Arg Val Arg 1 5 10 15 Arg Cys Trp Phe Ala Trp Gly Arg Arg Ser Thr Ser Gln Arg Asp Val 20 25 30 Arg Gln Val Arg Lys Arg Asn Val Met Arg Ser Met Ala Asn Val Glu 35 40 45 Pro Phe Ala Ala Asn Pro Lys Lys Pro Glu Ile Arg Thr * 50 55 60 <210> 98 <211> 646 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(70670..72607) <400> 98 Val Thr Leu Lys Arg Ala Cys Ser Leu Leu Thr Val Lys Ser Phe Ser 1 5 10 15 Glu Asp Glu Arg Val Ile Thr Gly Ile Ala Ser Thr Pro Ser Pro Asp 20 25 30 Arg Asp Gly Asp Ile Leu Glu Pro Glu Gly Ala Glu Phe Gly Ser Ala 35 40 45 Ile Pro Phe Leu Trp Gln His Asp His Ser Arg Pro Val Gly Gln Cys 50 55 60 Thr Val Arg Arg Val Ser Glu Gly Leu Glu Ile Thr Ala Thr Leu Val 65 70 75 80 Lys Pro Val Pro Asp Met Pro Ser Gln Leu Ala Ala Arg Leu Asp Glu 85 90 95 Val Trp Ala Ala Ile Lys Thr Gly Leu Val Arg Gly Leu Ser Val Gly 100 105 110 Phe Arg Pro His Glu Tyr Thr Phe Leu Asp Gly Gly Gly Leu His Phe 115 120 125 Leu Arg Trp Glu Leu Met Glu Val Ser Ala Val Thr Val Pro Ala Asn 130 135 140 Ala Glu Cys Thr Ile Arg Thr Ile Lys Ser Tyr Asp Arg Pro Phe Ser 145 150 155 160 Ala Ala Ser Gly Asn Arg Lys Pro Val Val Lys Ile Ala Ser Ser Ala 165 170 175 Gly Ala Ala Ala Gln Ser Thr Thr Val Phe His Lys Glu Lys Thr Ile 180 185 190 Met Asn Ile Gly Glu Gln Ile Lys Ser Phe Glu Asn Lys Arg Ala Ala 195 200 205 Leu Ala Ala Ser Leu Glu Glu Val Met Thr Lys Ala Ala Glu Glu Gly 210 215 220 Arg Thr Leu Asp Val Glu Glu Glu Glu His Tyr Asp Asn Thr Ala Ala 225 230 235 240 Glu Ile Arg Gln Val Asp Ala His Leu Lys Arg Leu Arg Glu Leu Glu 245 250 255 Ala Gly Lys Ala Ala Thr Ala Gln Pro Val Lys Gln Ala Gly Asn Gly 260 265 270 Asn Val Ala Ala Val Ala Ser Ala Pro Val Ile Arg Val Glu Gln Lys 275 280 285 Leu Asp Lys Gly Ile Gly Phe Ala Arg Phe Ala Lys Ser Leu Ala Ala 290 295 300 Ala Lys Gly Val Arg Ser Glu Ala Leu Glu Val Ala Arg Arg Gln Tyr 305 310 315 320 Pro Asp Asp Ser Arg Leu His His Val Leu Lys Ser Ala Val Gly Ala 325 330 335 Gly Thr Thr Thr Asp Pro Gln Trp Ala Gly Ser Leu Ser Glu Tyr Gln 340 345 350 Glu Tyr Ala Gln Asp Phe Ile Asp Tyr Leu Arg Pro Gln Thr Ile Ile 355 360 365 Gly Arg Phe Gly Gln Gly Gly Ile Pro Ala Leu Arg Gln Val Pro Phe 370 375 380 Asn Ile Arg Val His Ala Gln Val Ser Gly Gly Ala Ala Gly Trp Val 385 390 395 400 Gly Glu Gly Lys Ala Lys Pro Leu Thr Lys Phe Asp Phe Glu Ser Ile 405 410 415 Thr Phe Ser His Ala Lys Val Ser Ala Ile Ala Val Leu Thr Glu Glu 420 425 430 Leu Ile Arg Phe Ser Ser Pro Ala Ala Asp Ala Leu Val Arg Asn Ala 435 440 445 Leu Ala Glu Ala Val Val Ala Arg Leu Asp Thr Asp Phe Val Asp Pro 450 455 460 Lys Lys Ala Ala Val Ala Asp Val Ser Pro Ala Ser Ile Thr His Asp 465 470 475 480 Val Lys Gly Thr Ala Ser Thr Gly Asn Pro Asp Ala Asp Ala Glu Ala 485 490 495 Ala Phe Gly Gln Phe Val Ala Ala Asn Leu Gln Pro Thr Gly Ala Val 500 505 510 Trp Leu Met Ser Ser Thr Asn Ala Leu Ala Leu Ser Met Arg Lys Asn 515 520 525 Ala Leu Gly Gln Lys Glu Tyr Pro Asp Met Thr Leu Leu Gly Gly Ser 530 535 540 Phe Gln Gly Leu Pro Val Ile Val Ser Gln Tyr Val Gly Asp Gln Leu 545 550 555 560 Val Leu Val Asn Ala Pro Asp Ile Tyr Leu Ala Asp Asp Gly Gly Val 565 570 575 Ala Val Asp Met Ser Arg Glu Ala Ser Leu Glu Met Gln Ser Glu Pro 580 585 590 Gly Gly Asp Ser Thr Thr Pro Ser Pro Val Glu Leu Val Ser Met Phe 595 600 605 Gln Thr Gly Ser Val Ala Ile Arg Ala Glu Arg Trp Ile Asn Trp Arg 610 615 620 Arg Arg Arg Thr Ala Ala Val Ala Val Ile Thr Gly Val Asn Tyr Gly 625 630 635 640 Ser Ala Ser Gly Gly * 645 <210> 99 <211> 554 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(72671..74332) <400> 99 Met Ile Pro Val Trp Ser Thr Ala Cys Pro Asp Trp Ala Glu Arg Leu 1 5 10 15 Lys Lys Gly Leu Ser Ile Ile Pro Ala Pro Ile Tyr Pro Glu Gln Ala 20 25 30 Ala His Ala Leu Ala Ile Phe Lys Gln Leu Arg Ile Val Asp Ala Pro 35 40 45 Gly Ser Pro Thr Phe Gly Glu Ser Cys Ala Gln Trp Val Phe Asp Leu 50 55 60 Val Ala Ala Leu Phe Gly Ser Tyr Asp Ala Gln Thr Gly Val Arg His 65 70 75 80 Ile Lys Glu Val Phe Ile Leu Ile Pro Lys Lys Asn Ser Lys Ser Thr 85 90 95 Leu Ala Ala Gly Ile Met Met Thr Ala Leu Leu Leu Asn Trp Arg Gln 100 105 110 Ala Ala Gly Tyr Thr Ile Leu Ala Pro Thr Val Glu Val Ala Ala Asn 115 120 125 Ala Phe Asn Pro Ala Arg Asp Met Val Arg Arg Asp Asp Asp Leu Asp 130 135 140 Asp Leu Cys Gln Val Gln Thr His Ile Arg Thr Ile Thr His Arg Val 145 150 155 160 Thr Asp Thr Thr Leu Lys Val Val Ala Ala Asp Pro Asn Thr Val Ser 165 170 175 Gly Ile Lys Ser Val Gly Thr Leu Ile Asp Glu Leu Trp Leu Phe Gly 180 185 190 Lys Gln Tyr Lys Ala Glu Asp Met Leu Arg Glu Ala Ile Gly Gly Leu 195 200 205 Ala Ser Arg Pro Glu Gly Phe Val Val Tyr Thr Thr Thr Gln Ser Asn 210 215 220 Glu Pro Pro Ala Gly Val Phe Arg Gln Lys Leu Gln Tyr Ala Arg Asp 225 230 235 240 Val Arg Asp Gly Lys Ile His Asp Pro His Phe Leu Pro Val Ile Phe 245 250 255 Glu His Pro Pro Glu Met Val Glu Ser Gly Ala His Leu Leu Met Glu 260 265 270 Asn Leu Ala Met Val Asn Pro Asn Leu Gly Tyr Ser Val Asp Glu Ala 275 280 285 Phe Leu Tyr Arg Glu Tyr Arg Lys Ala Arg Glu Ala Gly Glu Glu Ala 290 295 300 Phe Arg Gly Phe Met Ser Lys His Ala Asn Val Glu Ile Gly Leu Ala 305 310 315 320 Leu Arg Ser Asp Arg Trp Ala Gly Ala Asp Phe Trp Glu Gln Gln Gly 325 330 335 Arg Arg Val Ser Leu Asp Asp Ile Leu Gln Arg Ala Asp Val Val Thr 340 345 350 Val Gly Ile Asp Gly Gly Gly Leu Asp Asp Leu Leu Gly Met Tyr Val 355 360 365 Ile Gly Arg Asp Arg Glu Thr Arg Glu Trp Leu Gly Trp Gly His Ala 370 375 380 Trp Ala His Glu Thr Ala Val Val Arg Arg Lys Ser Glu Ala Ser Arg 385 390 395 400 Phe Gln Asp Leu Val Ala Cys Gly Asp Met Thr Ile Val Arg Arg Val 405 410 415 Gly Asp Asp Thr Ala Glu Val Ala Glu Tyr Val Arg Arg Ile His Glu 420 425 430 Ala Glu Leu Leu Asp His Ile Gly Ile Asp Pro Ser Gly Val Gly Gln 435 440 445 Ile Leu Asp Ser Leu Ala Glu Ala Gly Ile Pro Asp Gly Ile Val Val 450 455 460 Gly Ile Ser Gln Gly Trp Lys Leu Gly Gly Ala Ile Lys Thr Thr Glu 465 470 475 480 Arg Lys Leu Ala Glu Gly Val Leu Val His Gly Asp Gln Pro Leu Met 485 490 495 Ala Trp Cys Val Gly Asn Ala Arg Val Glu Pro Lys Gly Asn Ala Ile 500 505 510 Leu Ile Thr Lys Gln Ala Ser Gly Arg Gly Lys Ile Asp Pro Leu Met 515 520 525 Ala Leu Phe Asn Ala Val Ser Leu Met Ser Leu Asn Pro Glu Pro Lys 530 535 540 Lys Lys Glu Tyr Ala Val Phe Phe Ile * 545 550 <210> 100 <211> 188 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(74329..74892) <400> 100 Val Leu Thr Thr Gln Lys Arg Lys Phe Ala Leu Ala Leu Met Ser Gly 1 5 10 15 Lys Asn Lys Thr Ala Ser Ala Leu Ala Ala Gly Tyr Ser Ala Lys Thr 20 25 30 Ala Arg Val Lys Gly Ser Gln Leu Ala Lys Asp Pro Glu Val Leu Ala 35 40 45 Phe Ile Ala Arg Lys Gln Cys Glu Thr Val Glu Val Asp Glu Val Pro 50 55 60 Val Tyr Arg Gln Lys Lys Ser Glu Pro Glu Asp Lys Pro Arg Arg Arg 65 70 75 80 Glu Ala Ala Ala Ile Pro Gln Pro Asp Glu Thr Asn Pro Glu Met Pro 85 90 95 Pro Pro Val Val Ile Ser Pro Gly Ile Glu Tyr Met Glu Asp Gly Leu 100 105 110 Pro Asp Pro Val Lys Ala Met Gly Arg Leu Leu Val Glu Asn Ile Asn 115 120 125 Thr Asp Pro Arg Leu Ala Leu Asp Ala Ala Tyr Lys Leu Ala Gln Phe 130 135 140 Thr His His Lys Lys Gly Asp Ala Gly Lys Lys Ser Ala Lys Gly Asp 145 150 155 160 Ala Ala Lys Lys Ala Ala Asn Arg Phe Ala Val Pro Pro Pro Pro Arg 165 170 175 Leu Val Val Asn Asn Asp Asn Glu Gly Asn Gly * 180 185 <210> 101 <211> 48 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(75076..75219) <400> 101 Met Ala Arg Ser Gly Pro Thr Glu Ser Leu Ala Cys Asp Gln Thr Arg 1 5 10 15 Gly Gly Ser Ser Gly Glu Lys Lys Arg Ser Pro Trp Thr Pro Arg Pro 20 25 30 Leu Ser Arg Arg Glu Lys Ile Pro Val Ser Gly Gln Leu Thr Cys * 35 40 45 <210> 102 <211> 122 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(75182..75547) <400> 102 Met Ala Val Leu Arg Thr Leu Pro Gly Arg Ile Lys Thr Leu Asn Thr 1 5 10 15 Arg Arg Ile Asn Val Leu Arg Gly Glu Gln Arg Arg Val Ser Gly Ser 20 25 30 Ala Arg Val Ser Leu Lys Arg Arg Ile Trp Arg Arg Asp Ala Gly His 35 40 45 Cys Cys Leu Cys Arg Arg Val Val Asp Leu Cys Asp Ser Glu Leu Asp 50 55 60 His Arg Ile Ala Leu Gln Phe Gly Gly Gly Asn Glu Glu Thr Asn Leu 65 70 75 80 Trp Thr Leu Cys Thr Glu Cys His Arg Gln Lys Ser Ala Ser Glu Ala 85 90 95 Ala Ser Gly Met Pro Asp Pro Thr Leu Pro Glu Leu Pro Asp Gly Thr 100 105 110 Leu Arg Ala Asp Gly Ile Thr Gly Leu * 115 120 <210> 103 <211> 76 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(75589..75816) <400> 103 Met Ser Ser Lys Asn Arg Pro Arg Arg Thr Thr Thr Arg Asn Ile Arg 1 5 10 15 Phe Pro Asn Gln Met Ile Glu Gln Ile Asn Ile Ala Leu Asp Gln Lys 20 25 30 Gly Ser Glu Asn Phe Ser Ala Trp Val Ile Glu Ser Cys Arg Arg Glu 35 40 45 Leu Ala Ala Asp Ile Lys Tyr Ala Arg Gln Leu Thr Ile Lys Lys Asn 50 55 60 Asp Thr Gln Tyr Ala Leu Arg Trp Leu Phe Ile * 65 70 75 <210> 104 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(76241..76426) <400> 104 Met Arg Glu Leu Lys Met Lys Leu Cys Val Leu Met Leu Pro Leu Val 1 5 10 15 Val Ser Ala Cys Gly Ser Thr Pro Pro Ala Pro Val Pro Cys Val Lys 20 25 30 Pro Pro Ala Pro Pro Ala Trp Ile Met Gln Pro Ala Pro Asp Trp Gln 35 40 45 Thr Pro Leu Asn Gly Ile Ile Ser Ser Ser Glu Asn Gly * 50 55 60 <210> 105 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(76179..76646) <400> 105 Met Asn Arg Val Leu Cys Val Val Ile Ile Val Leu Ala Val Gly Tyr 1 5 10 15 Gly Ala Leu Trp Leu Ala Thr Asn His Tyr Arg Asp Asn Ala Leu Thr 20 25 30 Tyr Lys Ala Gln Arg Asp Lys Lys Ala Arg Glu Leu Glu Gln Ala Asn 35 40 45 Ala Thr Ile Thr Asp Met Gln Val Arg Gln Arg Asp Val Ala Ala Leu 50 55 60 Asp Ala Lys Tyr Ser Arg Glu Leu Ala Asp Ala Arg Ala Glu Asn Glu 65 70 75 80 Thr Leu Arg Ala Asp Val Ala Ala Gly Arg Lys Arg Leu Arg Ile Asn 85 90 95 Ala Thr Cys Ser Gly Thr Val Arg Glu Ala Thr Gly Thr Ser Gly Val 100 105 110 Asp Asn Ala Thr Gly Pro Arg Leu Ala Asp Thr Ala Glu Arg Asp Tyr 115 120 125 Phe Ile Leu Arg Glu Arg Leu Met Thr Met Gln Lys Gln Leu Glu Gly 130 135 140 Ala Gln Asp Tyr Ile Arg Thr Gln Cys Leu Asn * 145 150 155 <210> 106 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(76800..77369) <400> 106 Met Asn Met Met Ala Val Pro Phe His Gly Asn Ser Leu Tyr Val Val 1 5 10 15 Asn His Asn Gly Glu Pro Tyr Val Pro Met Lys Pro Val Val Ala Gly 20 25 30 Met Gly Leu Ala Trp Gln Ser Gln Leu Ala Lys Leu Arg Gln Arg Phe 35 40 45 Ala Ser Thr Ile Thr Glu Ile Val Met Val Ala Glu Asp Gly Lys Gln 50 55 60 Arg Asn Met Val Ser Met Pro Leu Arg Lys Leu Ala Gly Trp Leu Gln 65 70 75 80 Thr Ile Asn Pro Asn Lys Val Lys Pro Glu Ile Arg Asp Lys Val Ile 85 90 95 Arg Tyr Gln Glu Glu Cys Asp Asp Val Leu Tyr Glu Tyr Trp Thr Lys 100 105 110 Gly Phe Val Val Asn Pro Arg Lys Met Ser Val Met Glu Glu Leu Asn 115 120 125 Gln Ala Cys Ala Asp Met Lys Arg Asp Lys Asn Ile Ala Ser Val Phe 130 135 140 Ala Thr Gly Leu Asn Glu Trp Lys Gln Val Lys Ala Ala His Val Ser 145 150 155 160 Lys Ile Arg Thr Leu Val Asn Glu Ala Asn Met Leu Ile Asp Phe Val 165 170 175 Leu Ala Asp Thr Gly Lys Gly Lys Ile Thr Lys Ala Asp * 180 185 <210> 107 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(77640..78173) <400> 107 Met Asn Ala Lys Ile Arg Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Gly Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Thr Arg Gly Asp Gly Lys Pro Val Ile 50 55 60 Pro Gly Met Lys Leu Ser Lys Glu Lys Cys Asp Arg Val Asn Ala Ile 65 70 75 80 Glu Arg Asp Lys Ala Leu Ala Trp Val Glu Lys Asn Ile Arg Val Pro 85 90 95 Leu Thr Glu Pro Gln Lys Ala Gly Ile Ala Ser Phe Cys Pro Tyr Asn 100 105 110 Ile Gly Pro Gly Lys Cys Phe Pro Ser Thr Phe Tyr Arg Arg Ile Asn 115 120 125 Ala Gly Asp Arg Lys Gly Ala Cys Glu Ala Ile Arg Trp Trp Ile Lys 130 135 140 Asp Gly Gly Arg Asp Cys Arg Ile Arg Ser Asn Asn Cys Tyr Gly Gln 145 150 155 160 Val Ser Arg Arg Asp Gln Glu Ser Ala Leu Ala Cys Trp Gly Ile Asp 165 170 175 Arg * <210> 108 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(78224..78568) <400> 108 Met Lys Lys Lys Tyr Glu Leu Val Val Lys Gly Ile Asn Asn Tyr Pro 1 5 10 15 Asp Lys Ile Thr Val Thr Val Ala Pro Glu Ile Gly Gly Tyr Pro Ser 20 25 30 Leu Leu Leu Pro Asp Val Ala Ile Ser Leu Asp Arg Thr Glu Gly Ala 35 40 45 Thr Leu Glu Phe Tyr Glu Ala Glu Ala Lys Lys Gln Ala Lys Gln Phe 50 55 60 Phe Met Asp Val Ala Ala Gly Leu Cys Glu Gly Asp Gly Pro Leu Pro 65 70 75 80 Glu Lys Arg Pro Val Ile Leu Glu Ala Gln Asp Val Leu Ile Thr Tyr 85 90 95 Arg Gly Lys Leu Pro Gly Ile Ile Thr Gly Ser Leu Lys Thr Pro Pro 100 105 110 Leu Ala * <210> 109 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(78573..78779) <400> 109 Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser Ala Val Gly 1 5 10 15 Thr Gly Tyr Trp Leu Leu Gln Leu Leu Asp Lys Val Ser Pro Ser Gln 20 25 30 Trp Val Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly Leu Leu Thr 35 40 45 Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Lys Glu Asp Arg Arg Lys Ala 50 55 60 Ala Arg Gly Glu * 65 <210> 110 <211> 617 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(79228..81078) <400> 110 Met Ser Ile Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Glu Lys Leu Thr His Lys Leu Lys Glu Gly Trp Gln Pro Phe 20 25 30 Gly Ser Pro Val Ala Ile Thr Pro Tyr Thr Leu Met Gln Ala Ile Thr 35 40 45 Ala Glu Gly Asp Val Val Val Ser Gly Ala Thr Glu Pro Asp Trp Tyr 50 55 60 Tyr Val Ile Val Leu Ala Gly Gln Ser Asn Ala Met Ala Tyr Gly Glu 65 70 75 80 Gly Leu Pro Leu Pro Asp Ser Tyr Asp Ala Pro Asp Pro Arg Ile Lys 85 90 95 Gln Leu Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Ala Ala Cys Arg 100 105 110 Tyr Asn Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln Asp 115 120 125 Met Ser Thr Leu Asn His Pro Lys Ala Asp Leu Ser Lys Gly Gln Tyr 130 135 140 Gly Cys Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro Tyr 145 150 155 160 Ile Pro Asn Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly Gly 165 170 175 Ser Ala Phe Thr Gln Gly Ala Glu Gly Thr Phe Ser Glu Ser Thr Gly 180 185 190 Ala Ser Gln Asp Ser Ala Arg Trp Gly Val Gly Lys Pro Leu Tyr Gln 195 200 205 Asp Leu Ile Ser Arg Thr Lys Ala Ala Leu Gln Lys Asn Pro Lys Asn 210 215 220 Val Leu Leu Ala Val Cys Trp Met Gln Gly Glu Phe Asp Met Ser Ala 225 230 235 240 Ala Thr His Ala Gln Gln Pro Ala Leu Phe Thr Ala Met Leu Ala Gln 245 250 255 Phe Arg Ala Asp Leu Ser Val Phe Asn Ala Gln Cys His Gly Gly Ser 260 265 270 Ala Ala Asp Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Tyr Trp Lys 275 280 285 Asn Thr Tyr Ala Thr Gln Tyr Asp Thr Val Tyr Gly Gly Tyr Lys Asn 290 295 300 Arg Glu Ser Glu Gly Val Tyr Phe Val Pro Phe Met Thr Asp Gly Asn 305 310 315 320 Gly Val Asn Thr Ala Thr Asn Ala Pro Ala Glu Asp Pro Asp Ile Pro 325 330 335 Ala Ser Gly Tyr Tyr Gly Ala Ala Ser Arg Thr Asn Gly Asn Gln Val 340 345 350 Ser Ser Asn Arg Pro Thr His Phe Ser Ser Trp Ala Arg Arg Ser Ile 355 360 365 Ile Pro Asp Arg Leu Ala Thr Ala Ile Leu Asn Ala Ala Gly Arg Thr 370 375 380 Ser Ala Phe Ile Ser Gly Lys Ala Pro Glu Ile Lys Pro Ser Pro Gly 385 390 395 400 Gly Asn Thr Pro Ser Gly Pro Ser Ala Asp Thr Ser Val Arg Thr Ile 405 410 415 Ser Leu Leu Pro Ala Ala Gly Glu Ala Ala Ala Gln Gly Trp Ser Ile 420 425 430 Lys Asp Gly Gly Ile Gln Leu Ser Asp Gly Val Phe Lys Ile Thr Arg 435 440 445 Gln Ser Asn Lys Thr Trp Ser Leu Thr His Pro Val Asp Asp Ala Ile 450 455 460 Thr Leu Leu Thr Gln Gly Gly Arg Leu Thr Cys Lys Phe Arg Leu Ser 465 470 475 480 Gly Ala Leu Thr Asn Asn Gln Phe Gly Leu Gly Ile Tyr Leu Tyr Thr 485 490 495 Asp Ala Pro Val Pro Asp Gly Val Ala Met Thr Gly Thr Gly Asn Pro 500 505 510 Phe Leu Met Ser Tyr Phe Thr Gln Thr Thr Asp Gly Arg Val Asn Leu 515 520 525 Met His His Arg Lys Ala Gly Asn Thr Lys Leu Gly Glu Phe Gly Asp 530 535 540 Tyr Gly Asn Asp Trp Gln Thr Leu Glu Leu Val Phe Thr Ala Gly Ser 545 550 555 560 Ala Thr Val Thr Pro Lys Leu Asn Gly Val Ala Gly Pro Ala Phe Gln 565 570 575 Val Ile Lys Asp Ser Leu Thr Leu Gly Leu Asn Ala Leu Thr Leu Thr 580 585 590 Asp Val Thr Lys Asn Ala Ala Tyr Gly Val Glu Ile Glu Ser Leu Val 595 600 605 Leu Glu Ile Asn Ala Pro Ala Ala * 610 615 <210> 111 <211> 43 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(81127..81255) <400> 111 Met Leu Cys His Lys Ser Val Ile Ser Val Phe Leu Lys Leu Ser Ser 1 5 10 15 Leu Ser Leu Tyr Phe Arg Leu Arg Met Ala Arg Pro Phe Phe Tyr Asp 20 25 30 Gln Pro Leu Ala Asp Gly His Pro Val Ile * 35 40 <210> 112 <211> 89 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(81400..81666) <400> 112 Met Trp Arg Trp Pro Leu Arg Arg Gln Thr Ala Lys Leu Ser Arg Lys 1 5 10 15 Ser Ala Arg Cys Trp Lys Arg Leu Pro Val Phe Trp Val Phe Val Trp 20 25 30 Arg Ile Thr Cys Asp Gly Lys Thr Ala Pro Asp Cys Gly Cys Thr Pro 35 40 45 Ala Val Ser Gly Gly Asp Gly Gly Phe His Gln Gln Asn His Val Gly 50 55 60 Ala Gly Gly Trp Gly Ala Gly Leu Arg His Cys Gly Ile Ala Val Ala 65 70 75 80 Gly Asp Lys Lys Lys Gln Pro Ala * 85 <210> 113 <211> 143 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(81557..81985) <400> 113 Leu Val Phe Leu Val Lys Lys Ala Arg Arg Ala Ala Thr Glu Ile Lys 1 5 10 15 Lys Phe Glu Lys Arg Asp Leu Ala Gln Val Val Ile Asn Ala Ala Tyr 20 25 30 Leu Val Ala Cys Ala Asp Gly Glu Cys Glu Ala Ser Glu Lys Ala Lys 35 40 45 Ile Glu Gln Val Leu Arg Asn Gln Pro Ala Leu Ser Ala Phe Thr Ser 50 55 60 Glu Ile Asn Ala Ile Ser Ala Thr Ile Ile Gly Gln Leu Asp Thr Asn 65 70 75 80 Phe Lys Thr Gly Arg Arg Ala Ala Leu Arg Glu Ile Glu Asp Val Lys 85 90 95 His Asp Thr Arg Glu Ala Glu Asp Val Leu Asp Val Ala Val Ala Ile 100 105 110 Ala Glu Ala Asp Gly Glu Ile Glu Pro Glu Glu Arg Lys Val Leu Glu 115 120 125 Glu Ile Ala Gly Val Leu Gly Leu Arg Leu Glu Asn His Leu * 130 135 140 <210> 114 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(82049..82213) <400> 114 Leu Pro Ser Lys Gln Ser Val Thr Gly Ser Thr Pro Val Gln Arg Ala 1 5 10 15 Thr Leu Ile Phe Pro Ala Arg Phe Cys Gly Pro Phe Leu Tyr Leu Arg 20 25 30 His Ala Arg His Ile Pro Thr Thr Glu Pro Phe Gly Gly Gly Gly Glu 35 40 45 Leu Thr Glu Trp Ser Val * 50 <210> 115 <211> 230 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(82625..83314) <400> 115 Met Asn Asn His Tyr Leu Gln Phe Val Arg Glu Gln Leu Ile Ile Ala 1 5 10 15 Thr Ala Asp Leu Ser Gly Ala Thr Lys Gly Gln Leu Glu Ala Trp Gln 20 25 30 Glu Asn Ala Met Phe Asp Thr Gly Arg Tyr Arg Arg Lys Lys Ile Arg 35 40 45 Tyr Arg Asp Glu Val Thr Gly Lys Met Ile Thr Arg Asp Asn Pro Pro 50 55 60 Ile Pro Gly Lys Gln Ser Leu Ala Lys Val Thr Ser Ile Pro Leu Val 65 70 75 80 Ser Pro Val Glu Phe Ser Thr Ser Ser Trp Arg Arg Ala Val Leu Ser 85 90 95 Leu Glu Glu His His Lys Ala Trp Leu Leu Trp Cys Tyr Ser Gly Ser 100 105 110 Ile Cys Trp Glu Tyr Gln Ile Ala Ile Thr Gln Trp Ala Trp Asn Glu 115 120 125 Phe Asn Thr Gln Ser Gly Thr Arg Lys Ile Ala Gly Lys Thr Gln Glu 130 135 140 Arg Leu Lys Lys Leu Ile Trp Leu Ala Ala Gln Ala Val Lys Ala Glu 145 150 155 160 Leu Phe Gly Gly Glu Gly Tyr Glu Tyr Lys Glu Leu Ala Leu Leu Val 165 170 175 Gly Val Thr Thr Lys Asn Trp Ser Lys Thr Phe Thr Arg His Trp Val 180 185 190 Ala Met Lys His Ile Phe His Arg Leu Asp Ser Glu Ala Leu Leu Phe 195 200 205 Val Met Arg Thr Arg Ser Lys Gln Lys Ala Ala Phe Ser Lys Gln Ser 210 215 220 Val Ala Lys Val Asp * 225 <210> 116 <211> 120 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(83311..83670) <400> 116 Met Arg Ile Glu Phe Val Leu Pro Tyr Pro Pro Thr Val Asn Thr Tyr 1 5 10 15 Trp Arg Arg Arg Gly Ser Thr Tyr Phe Val Ser Lys Ala Gly Glu Arg 20 25 30 Tyr Arg Arg Asp Val Ala Leu Ile Val Arg Gln Gln Arg Leu Lys Leu 35 40 45 Asn Leu Ser Gly Arg Leu Val Ile Lys Ile Ile Ala Glu Pro Pro Asp 50 55 60 Lys Arg Arg Arg Asp Leu Asp Asn Ile Leu Lys Ala Pro Leu Asp Val 65 70 75 80 Leu Thr His Ala Gly Leu Leu Ile Asp Asp Glu Gln Phe Asp Glu Ile 85 90 95 Asn Ile Val Arg Gly Gln Leu Val Pro Gly Glu Arg Leu Gly Ile Lys 100 105 110 Ile Thr Glu Leu Glu Cys Ala * 115 <210> 117 <211> 350 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(83683..84732) <400> 117 Val Arg Val Leu Leu Arg Pro Val Leu Val Pro Glu Leu Gly Leu Val 1 5 10 15 Ile Val Lys Pro Gly Arg Glu Ser Met Ser Ala Phe His Asn Gly Arg 20 25 30 Ile Leu Val Glu Pro Glu Pro Lys Ser Met Arg Ala Leu Pro Ser Gly 35 40 45 Val Val Pro Ala Val His Gln Pro Leu Ala Glu Asp Lys Ser Leu Leu 50 55 60 Pro Phe Phe Ser Asp Glu Arg Val Ile Arg Ala Ala Gly Gly Ala Gly 65 70 75 80 Ala Leu Ser Asp Trp Leu Leu Arg His Val Lys Ser Cys Gln Trp Leu 85 90 95 His Gly Asp Tyr His His Ser Glu Thr Val Ile His Arg Tyr Gly Thr 100 105 110 Gly Ala Met Val Leu Cys Trp His Cys Asp Asn Gln Leu Arg Glu Gln 115 120 125 Thr Ser Asp Ser Leu Asp Gln Leu Ala Gln Gln Asn Leu Ala Ala Trp 130 135 140 Met Ile Asp Ile Ile Arg His Ala Met Asn Gly Ala Gln Glu Arg Glu 145 150 155 160 Leu Ser Leu Ala Glu Leu Ser Trp Trp Ala Val Arg Asn Gln Val Ala 165 170 175 Asp Ala Leu Pro Glu Ala Val Leu Arg Arg Ser Leu Gly Leu Arg Ala 180 185 190 Glu Lys Ile Arg Ser Val Tyr Arg Glu Ser Asp Ile Ile Pro Gly Glu 195 200 205 Gln Thr Ala Thr Ser Ile Leu Lys Gln Arg Thr Lys Asn Ile Ala Leu 210 215 220 Pro Pro His Thr His Gln Gln Gln Asn Pro Pro Gln Glu Lys Thr Val 225 230 235 240 Val Ser Ile Ala Val Asp Pro Glu Ser Pro Glu Ser Phe Met Lys Arg 245 250 255 Pro Lys Arg Arg Arg Trp Val Asn Glu Lys Tyr Thr Arg Trp Val Lys 260 265 270 Thr Gln Pro Cys Ala Cys Cys Gly Lys Pro Ala Asp Asp Pro His His 275 280 285 Leu Ile Gly His Gly Gln Gly Gly Met Gly Thr Lys Ser His Asp Ile 290 295 300 Phe Thr Leu Pro Leu Cys Arg Glu His His Asn Glu Leu His Ala Asp 305 310 315 320 Pro Leu Ala Phe Glu Glu Lys His Gly Ser Gln Val Asp Leu Ile Phe 325 330 335 Arg Phe Leu Asp His Ala Phe Ala Thr Gly Val Leu Gly * 340 345 <210> 118 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(85437..85592) <400> 118 Met Leu Thr Gly Ala Phe Leu Cys Leu Pro Tyr Gly Gly Met Pro Glu 1 5 10 15 Ala Asp Ser Leu Lys His Pro Gln Gln Phe Tyr Leu Thr Leu Ala Leu 20 25 30 Pro Gln Thr Val Phe Thr Arg Tyr Gly Asn Ser His Ile Val Met Asn 35 40 45 Ser Val Pro * 50 <210> 119 <211> 35 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(85581..85685) <400> 119 Met Ser Asp Asp Ile Ser Leu Ala Met Glu Gly Ala Leu Ala Val Ile 1 5 10 15 Ala Val Val Gly Val Tyr Cys Leu Val Val Phe Leu Met Asp Arg Leu 20 25 30 Gly Asn * <210> 120 <211> 195 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(85801..86385) <400> 120 Met Thr Thr Phe Thr Lys Glu Gln Leu Ile Ser His Val Ser Glu Asn 1 5 10 15 Val Lys Ala Met Lys Phe Ala Val Lys Gln Thr Ala Phe Lys Asn Ser 20 25 30 Leu Glu Ala Ile Glu Leu Asp Leu Ala Leu Ala Leu Val Ala Gln Ala 35 40 45 Ser Leu Glu Ala Glu Pro Val Leu Tyr Met Asn Arg Phe Thr Gly Lys 50 55 60 Thr Phe Ser Leu Glu Glu Gln Pro Gly Ala Asp Lys Glu Pro Glu Ile 65 70 75 80 Tyr Val Pro Leu Tyr Ala Ala Pro Pro Asp Ser Ala Ala Met Leu Gln 85 90 95 Ala Gly Asn Phe Arg Glu Lys Lys Gly Ser Ser Thr Asn Asn Phe Arg 100 105 110 Glu Ile Ser Glu Thr Ser Thr Asn Tyr Pro Val Thr Leu Asp Asp Trp 115 120 125 Ile Ser Cys Ser Glu Arg Met Pro Asp Asp Gly Gln His Val Ile Ile 130 135 140 Leu Cys Asp Gly Ala Phe Val Leu Tyr Ala Gln Tyr Arg Asp Gly Glu 145 150 155 160 Phe Phe Asp Val Val Arg Asn Gly Asp Glu Phe Phe Glu Thr Gln Ser 165 170 175 Arg Asn Val Thr Asp Trp Met Pro Leu Pro Glu Pro Pro Gln Glu Val 180 185 190 Arg Gln * <210> 121 <211> 132 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(86442..86837) <400> 121 Met Ala Lys Pro Phe Thr His Glu Gln Arg Glu Glu Leu Lys Ala Arg 1 5 10 15 Ile Ile Gly Leu Val Arg Lys Asn Glu Arg Met Thr Ile Ser Gln Leu 20 25 30 Glu Arg Ala Thr Gly Ala Gly Trp His Ser Val Arg Arg Cys Leu Val 35 40 45 Asp Val Leu Ala Cys Gly Asp Leu Tyr Met Pro Gly Lys Tyr Gly Val 50 55 60 Phe Thr Ser Glu Gln Val Tyr Arg Val Trp Arg Lys Ala Ala Glu Lys 65 70 75 80 Ala Thr Asp Gln Thr Leu Ile Arg Lys Leu Pro Asp Gly Glu Ile Arg 85 90 95 Arg Tyr Asp Arg Gln Gln Asn Ile Ile Cys Gly Glu Cys Arg Lys Ser 100 105 110 Glu Val Met Leu Arg Val Leu Ala Phe Tyr Gln Gly Asn Phe Gln Glu 115 120 125 Ala Val Leu * 130 <210> 122 <211> 223 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(86853..87521) <400> 122 Val Gly Thr Gln Lys Asn Gly Val Val Asp Lys Thr Gly His Thr Trp 1 5 10 15 Phe Leu Ala Val Glu Gly Glu Ala Gly Val Thr Glu Gly Gln Ala Leu 20 25 30 Gln Pro Glu Ala Pro Asp Val Val Thr Glu Glu Val Ala Pro Lys Val 35 40 45 Thr Ala Asp Met Met Val Glu Phe Ile Gly Gln Asp Gly Ala Lys Thr 50 55 60 Cys Glu Glu Leu Ala Gly Lys Phe Gly Val Ser Thr Arg Lys Val Ala 65 70 75 80 Ser Thr Leu Ala Val Val Thr Ala Thr Gly Arg Leu Ala Arg Val Asn 85 90 95 Gln Asn Gly Lys Phe Arg Tyr Cys Met Ser Gly Gly Asn Leu Pro Ala 100 105 110 Asp Pro Lys Ala Ala Pro Val Thr Lys Asn Asp Gly Lys Ala Phe Pro 115 120 125 Gln Pro Ala Gly Ala Ala Leu Pro Val Arg Glu Ala Ala Thr Gln Glu 130 135 140 Glu Ile Lys Thr Glu Thr Val Ala Asp Ile Val Gln Pro Leu Pro Ser 145 150 155 160 Phe Thr Glu Thr Gln Ala Asp Glu Leu Ile Phe Pro Ser Leu Arg Arg 165 170 175 Ala Asn Leu Ala Leu Arg Arg Ala Lys Ser Asp Val Gln Lys Trp Glu 180 185 190 Arg Val Cys Ala Ala Leu Arg Glu Leu Asn Lys His Arg Asp Ile Val 195 200 205 Arg Gln Ile Thr Asp Ser Ser Arg Arg Val Val Ser Glu Lys * 210 215 220 <210> 123 <211> 247 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(87648..88388) <400> 123 Met Lys Asn Ile Ala Ala Val Gly Val Leu Glu Arg Ile Arg Arg Leu 1 5 10 15 Ala Pro Gln Gly Ala Val Pro Pro Tyr Arg Thr Val Glu Glu Trp Arg 20 25 30 Glu Trp Gln Leu Ala Glu Gly Arg Lys Arg Ser Glu Glu Ile Asn Arg 35 40 45 Leu Asn His Gln Val Arg Val Glu Lys Ile Leu Asn Arg Ala Gly Ile 50 55 60 Gln Pro Leu His Arg Lys Cys Ser Phe Gly Asn Tyr Arg Val Gln Asn 65 70 75 80 Asp Gly Gln Arg His Ala Leu Ser Gln Ala Lys Ser Ile Ala Asp Glu 85 90 95 Leu Met Thr Gly Cys Thr Asn Phe Val Phe Ser Gly Lys Pro Gly Thr 100 105 110 Gly Lys Asn His Leu Ala Ala Ala Ile Gly Asn Arg Leu Met Ala Lys 115 120 125 Gly Arg Ser Val Ile Ile Val Thr Val Ser Asp Val Met Ser Val Leu 130 135 140 His Asp Gly Tyr Asp Asn Gly Gln Ser Gly Glu Lys Phe Leu Gln Glu 145 150 155 160 Leu Cys Gly Val Asp Leu Leu Val Leu Asp Glu Ile Gly Met Gln Arg 165 170 175 Asp Thr Arg Asn Glu Gln Val Thr Leu Asn Gln Ile Val Asp Arg Arg 180 185 190 Thr Ala Ser Met Arg Ser Val Gly Met Leu Thr Asn Leu Asn His Ala 195 200 205 Ala Met Ser Thr Leu Leu Gly Asp Arg Val Met Asp Arg Met Thr Met 210 215 220 Asn Gly Gly Arg Trp Val Asn Phe Asn Trp Glu Ser Trp Arg Ser Asn 225 230 235 240 Val Gly Arg Gln Gly Met * 245 <210> 124 <211> 304 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(88395..89306) <400> 124 Met Ile Leu Ser Arg Val Ala Val Met Ala Arg Leu Ala Asp Tyr Ser 1 5 10 15 Asn Asp Glu Gly Val Ser Trp Pro Ala Ile Glu Thr Ile Arg Arg Gln 20 25 30 Ile Gly Ala Arg Ser Glu Ser Thr Val Lys Ser Ala Ile Ala Glu Leu 35 40 45 Ala Lys Glu Gly Trp Leu Thr Lys Glu Glu Arg Lys Val Gly Gly Arg 50 55 60 Asn Val Ser Asn Ile Tyr Arg Leu Asn Val Glu Lys Leu Glu Ala Ala 65 70 75 80 Ala Ala Ala Ala Arg Glu Ser Tyr Lys Pro Lys Arg Lys Ile Ser Pro 85 90 95 Ala Lys Asn Asp Pro Leu Thr Val Asp Pro Ser Asn Ile Ala Pro Ser 100 105 110 Thr Val Asp Pro Ser Asn Phe Asp Gly Ser Thr Val Asp Asn Lys Leu 115 120 125 Pro Ile Arg Gly Ala Met Ile Asp Pro Asp Pro Ser Val Leu Lys Pro 130 135 140 Asp Pro Ser Asp Lys Arg Ser Ser Cys Pro Asp Ala Ser Gln Pro Asp 145 150 155 160 Pro Gln Thr Ala Glu Gln Asn Phe Leu Thr Arg His Pro Asp Ala Val 165 170 175 Val Phe Ser Ala Lys Lys Arg Gln Trp Gly Ser Gln Glu Asp Leu Val 180 185 190 Cys Ala Gln Trp Ile Trp Gly Arg Ile Val Ser Leu Tyr Glu Gln Ala 195 200 205 Ala Ser Asp Asp Gly Glu Ile Thr Arg Pro Lys Glu Pro Asn Trp Thr 210 215 220 Ala Trp Ala Asn Asp Val Arg Thr Met Arg Met Leu Asp Gly Arg Thr 225 230 235 240 His Arg Gln Ile Cys Glu Met Phe Gly Arg Leu Gln Arg Asp Ser Phe 245 250 255 Trp Val Lys Asn Ile Met Ser Pro Ala Lys Leu Arg Glu Lys Trp Asp 260 265 270 Glu Leu Val Ile Arg Leu Gly Arg Ser Pro Ala Gln Arg Cys Val Asn 275 280 285 His Ile Ser Glu Pro Asp Thr Glu Ile Pro Pro Gly Phe Arg Gly * 290 295 300 <210> 125 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(89380..89805) <400> 125 Met Lys Ile Lys His Glu His Ile Arg Met Ala Met Asn Val Trp Ala 1 5 10 15 His Pro Asp Gly Glu Lys Val Pro Ala Ala Lys Ile Thr Lys Ala Tyr 20 25 30 Phe Glu Leu Gly Met Thr Phe Pro Glu Leu Tyr Asp Asp Ser His Pro 35 40 45 Glu Ala Leu Ala Arg Asn Thr Gln Lys Ile Phe Arg Trp Leu Asp Lys 50 55 60 Asp Thr Pro Asp Ala Val Glu Lys Met Gln Ala Leu Leu Pro Ala Ile 65 70 75 80 Glu Lys Ala Met Pro Pro Leu Leu Val Ala Arg Met Arg Ser His Ser 85 90 95 Ser Glu Tyr Tyr Arg Glu Ile Val Glu Arg Arg Asp Arg Leu Val Lys 100 105 110 Asp Val Asp Asp Phe Val Ala Ser Ala Val Val Leu Tyr Asp Gln Met 115 120 125 Asn Arg Gly Gly Pro Ala Gly Asn Ala Val Val Met His * 130 135 140 <210> 126 <211> 101 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(89802..90104) <400> 126 Met Thr Leu Lys Glu Phe Ile Lys Ser Leu Arg Val Gly Asp Ala Lys 1 5 10 15 Lys Phe Ala Ala Arg Leu Gly Val Ser Pro Ser Tyr Leu Ser Gln Met 20 25 30 Ala Ser Gly Arg Thr Ala Ile Ser Pro Thr Arg Ala Leu Met Ile Glu 35 40 45 Ser Ala Thr Glu Gly Gln Val Ser Arg Ala Glu Leu Arg Pro His Asp 50 55 60 Trp Glu Leu Ile Trp Pro Glu Tyr Ala Ser Gly Ile Arg Leu Gly Gln 65 70 75 80 Thr His Val Val His Ala Glu Gly Asp Cys Ser Ala Cys Leu Ser Asp 85 90 95 Gly Val Asp Ser * 100 <210> 127 <211> 145 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(90139..90573) <400> 127 Val Phe Asn Lys Pro Leu Ser Gln Val Phe Ala Cys Leu Val Ile Thr 1 5 10 15 Lys Asp Asn Tyr His Met Gln Lys Lys Glu Ile Arg Arg Leu Arg Leu 20 25 30 Lys Glu Trp Phe Lys Asp Lys Thr Leu Pro Pro Lys Glu Lys Ser Tyr 35 40 45 Leu Ser Gln Leu Met Ser Gly Arg Ala Ser Phe Gly Glu Lys Ala Ala 50 55 60 Arg Arg Ile Glu Gln Thr Tyr Gly Met Pro Glu Gly Tyr Leu Asp Ala 65 70 75 80 Glu Tyr Ala Glu Gln Pro Gly Gly Ser Pro Pro His Ala Gly Leu Thr 85 90 95 Ser Asn Gln Leu Glu Leu Leu Gln Ile Phe Ser Ala Phe Pro Glu Asp 100 105 110 Glu Gln Arg Gln Ile Ile Ser Glu Leu Lys Gln Lys Lys Glu Ser Met 115 120 125 Glu Asp Leu Ile Ala Arg Trp Ile Ala Ala Gln Lys Cys Arg Arg Ala 130 135 140 * <210> 128 <211> 76 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(90558..90785) <400> 128 Met Pro Pro Arg Leu Ser Tyr Lys Thr Gly Gly Asn Met Asn Arg Ala 1 5 10 15 Leu Ser Pro Met Val Ser Glu Phe Glu Thr Ile Glu Gln Glu Asn Ser 20 25 30 Tyr Asn Glu Trp Leu Arg Ala Lys Val Ala Thr Ser Leu Ala Asp Pro 35 40 45 Arg Pro Ala Ile Pro His Asp Glu Val Glu Arg Arg Met Ala Glu Arg 50 55 60 Phe Ala Lys Met Arg Lys Glu Arg Ser Lys Gln * 65 70 75 <210> 129 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(90787..91065) <400> 129 Met Leu Pro Val Leu Trp Leu Glu Ser Ala Asp Thr Asp Leu Asp Asp 1 5 10 15 Ile Thr Ser Tyr Ile Ala Arg Phe Asp Ile Asp Ala Ala Glu Arg Leu 20 25 30 Trp Gln Arg Leu Arg Gly Cys Val Leu Pro Leu Ser Glu His Pro Tyr 35 40 45 Leu Tyr Pro Pro Ser Asp Arg Val Pro Gly Leu Arg Glu Ile Val Ala 50 55 60 His Pro Asn Tyr Ile Ile Leu Tyr Arg Val Thr Thr Ser Ser Val Glu 65 70 75 80 Val Val Asn Val Ile His Ala Arg Arg Gln Phe Pro * 85 90 <210> 130 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(91270..91434) <400> 130 Met Asn Met Thr Ala Gly Phe Asn Phe Asn Asn Tyr Ala Ala Val Phe 1 5 10 15 Cys Ser Ala Thr Pro Ala Leu Arg Gly Asn Arg Gly Phe Leu Ser Gly 20 25 30 Arg Ser Gln Thr Ser Glu Trp Lys Ala Ser Arg Asp Arg Gln Arg Ser 35 40 45 Ser Asn Gly Ala Leu Tyr * 50 <210> 131 <211> 119 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(91361..91717) <400> 131 Val Gly Glu Val Lys His Gln Asn Gly Arg His Pro Gly Ile Gly Lys 1 5 10 15 Glu Ala Ala Met Ala Leu Tyr Ile Asp Ile Ser Ala Ile Ala Gly Gln 20 25 30 Val Arg Val Ile Arg Ala Val Thr Lys Arg Tyr Ala Pro Leu Leu Gln 35 40 45 Lys Val Ser Gly Glu Cys Thr Glu Asp Ile Val Asn Asp Phe Val Ile 50 55 60 Glu Leu Arg Gly Leu Ile Phe Ser Tyr Lys Val Thr Thr Ile Phe Ala 65 70 75 80 Asp Gly Ser Arg Glu Thr Val Arg Ala Leu Arg Leu Lys Gly Cys Val 85 90 95 Lys Asp Leu Ala Thr Thr Phe Trp Ala Arg Lys Leu Asp Cys Ile His 100 105 110 Asn Gln Phe Pro Leu Glu * 115 <210> 132 <211> 86249 <212> DNA <213> Escherichia coli O157:H7 <400> 132 ggcggtgagg gggaccgcct gaaataaatc tgacttaatc caggggtgtt atataatttc 60 attataaaca atgtattaca ctttttgttg tccgatatta tctaatgtat tcttagtgaa 120 gcgagagact aatggcatac tggatggcat accagagtga cgggaattag cgtatggcag 180 tattgacgga tacgaaagca agacatatca aacctgatga caaaccattg ccccatgggg 240 gaattaccgg actgaccctt catccttctt cagtaaaggg gcgggggaaa tgggtttttc 300 gttatgtaag tccggtgaca caaaaaagac gtaatgctgg attgggaact tacccagagg 360 tcagtattgc tgaagctgca cgtactgccc ggataatgcg agagcaactt gctgcaggtg 420 atgatcctct ggagattaaa aaggctgaat ctgagaaagt cgctatccca acatttgccg 480 atgcagccag gcgtgtacat gcagaactgt ctcctggatg ggaaaatcca aagcatgtaa 540 ggcagtggtt atcgacgctt gagaattacg cgtttcctca actgggagca aaaacgctgg 600 attcgattac ggctgcggac gtggcagaaa cactgcgtcc agtctggtta accttgtcag 660 aaacggcaag ccgggttaaa cagcgcattc atgttgttat gcagtgggga tgggcgcacg 720 gtttttgtgt agcaaatcct gttgatgtgg ttgaccattt gcttcctcag cagacaagag 780 gacgtgatga acaccaaccc gcaatgccct ggaggcagtt accgcttttt gtggcgacca 840 gtgtgtatac cgatgaacct tataatgtta cccgcgcact gttattaatg gtgatactta 900 cagcaactcg ctcgggcgaa gccaggggaa tgcgctgggc tgaaattgat tttcataagc 960 gggtatggac tatacctgca gaaagaatga aagccaggat acagcatcgt gttcctttat 1020 cccggcaggc tatttacatt ctggaaaata tacgtggcct gcatgatgaa ctggtgttcc 1080 cttcacccag aaagcagcag atcctttccg atatggtgtt gacaagtttt ctgcgtaaaa 1140 agaaagccgt cagtgacatt ccggggcgag ttgccacggc acatggtttt cgctcaacat 1200 tcagggactg gtgtagcgaa caggggtatt cgcgggatct ggcggaaagg gcgctcgctc 1260 atacgctgaa aaataaggtt gaggcggcat atcatcgtac tgatctactg gagcagcgtg 1320 taccgatgat gcaggcatgg gcggattatg tgatgtctca aattgtgaat aaataatagt 1380 gaaaatgtat attgtacgat catgatttga tatgtgatcg tagcagtagt aattaagaaa 1440 ccgcttttat gtcaaatgta ttgagctgat aattatcaga tcgtcaggaa agcgtatttt 1500 gattaacagg ggattactta acaatcccct ttttataaaa aataatttgc ctgtttaact 1560 cttcactcct gctgagactg aattattcct agtgcgtcat aaatcagtct tctgcgtagt 1620 ttattgtttt tatctgcacc atataacata aatatatttt caactttttc ttcaggtgtt 1680 ctgagataat ggataagaaa ggttatcatt ccaacacaat ggaataaagt gaatccatca 1740 aacaggctta tcaggtttcc ttttttttcc cgtgttgtaa gtattttttc gcgggtaaga 1800 atatttgcca gttcatgggg ggctgatatg tttctgctgt ctataatgtc atttatttta 1860 ccaagggcta tatcaacttc ctgtaatagg ttatttatca tagctgagtg aatgttattg 1920 gtttcatgtt cctgacagtt tatgaactta taaatcattg agttatacag aaatattact 1980 cttcctaata aatatgtgtt tgtgtcattt tgaagacagg actctgggta ttcgtgatcc 2040 agtgaaataa ggttaatgga ctcgccctga taagtcataa aataattgat gtcatttaat 2100 aatgctcgga tatttacatg atttttactg aattttattt taaatgctat ctttagtata 2160 gcaaacgcgg caatgataaa tccaaaaggt aatttctcat agttcagttt attgatggtg 2220 cgatgaacac tttcagtctt tcctgaagta agttgtctca aacagttaac aaattctgta 2280 tagccattta agacataatg gcatgaagaa tcttttaaag agttttctat gttttgtaat 2340 gtgacgccgt tgttcaatgt ataaatgtaa ccgccaaaga caatgttttc aatctcaacg 2400 acacaattta ttgttttttg ttcaggataa agataaatat cagaaatact atagtctcgt 2460 attgcgtcaa tggcatccca cgataatgca ctgtcaattt tcagtgtata aaatggtgag 2520 ttctcattag gaaagtaata tatgtatttg ttcagtatat tcattacatc tattgggttg 2580 gttaaatata ataactggca ttcatattct gaaacttctc tttcgcttat cagcatttta 2640 tataaagttg ccagggtgct tgttaatgaa gttcgtcttt cgaaagccag taatatagtg 2700 agataataac atgcaacctg aactttatct aagtcagaaa ttattttttc cttgtcttca 2760 ttacttaaat aaagcagatg tttacaggtt tctttgcatg tgttgatagt tgcgataagt 2820 tttgtttttc ctggtgtact gtttttgcga atattacgaa tgaattcata tacgccatca 2880 aagatatctt tgaaatgcgc attcgctggc gtgtatccgg ataaacataa cttaacgtaa 2940 tttcgcagat atgtccttgc agcatgatat atatcatcct cattatccgg tatctgagtg 3000 agaaaagaat gaatatgata gtaaaatgcc atctcattat ccgggcgata tgtgttcctg 3060 atgtcgagtg cgagaatcat tggtacaatg tcattaaaat atttttgttt tattatttga 3120 tgtgttttgt ctgtaaaaac agaatagtgc attagcttaa catagagatc ttcatatctc 3180 ctaaatataa cttttcgttg ttctttactc aatacttgtt ctttatcaat aatgtttatt 3240 aattcatcaa acatgtcgcc cagtgaatgt tgatgtgagg aaaaattttt aatatttcgg 3300 atgtcacggc tattctggtt tttagccaga acaccaaaac atgaaaagac atcatacatt 3360 atagtgataa aattatacat aacattctcc ttttattgca ctatataaaa ttttaacatt 3420 atatcatttt gcttttctgt taactggttt tcatttttga atcaatattt tctgaacagg 3480 gtaatagtac acgtattaac agattatgtc agaaggcccc ggtgatgcct tctgacgata 3540 gattaatgtt gtattctatt ggtatctgga gaccatatgg caacagttac agtatattct 3600 ccccgctgta attcctataa agtgtaccgt tatgatcaca gcacctcaga tcatgagcgt 3660 ttccagtgct aatcctgcaa acgtgtattt caactgaatt acatctacga aacccgaaaa 3720 ccaggcatta aagagcaaat tgttgaaatg gttcataacg gagccggggt tcgcgatagc 3780 tccagaacgc tgaaggtgga tatcaacacc gtcattctca ctttaaaaaa cgctcaccac 3840 gtaaagtaac catatctcca gccgccagtg tcgatgtggc acttatctgt gaacttgatg 3900 aacaatggag ttttgtcgaa aacaaagctc gtcagcagtg gcactggtac gcgtataaga 3960 ccaaagctga cggtgtgctg gcttacactt ttggtcctcg cactgatgaa acatgccgtg 4020 agttgccgga attcctgaag ccattctccg caggcatgat aaccagagac aaccggagca 4080 gttataccag agaaatgcca caggataagc atcttgtcgg caagatattt acccggcgca 4140 ttgagcgcaa caatctgaca cttcgtactc acatcaaacg acctgcccgg aaaacgattt 4200 gctttttacg ctccctggaa attcacgaaa agccattggt tcatttatcg aaaacacatg 4260 tactactgac aggagtcatt accagggcct cttttgctgt ttttttgcca tgaatgataa 4320 tgagaatcga cagcgataag ggaaaagtaa aataacacta atgctgtcgt tttctatcat 4380 attgattttt aattatttat tgtctttttt ctcaacccat ttttttacgc agacaaattt 4440 acccggggaa tacaaactgt aacgacagtt caccacacta tgggggataa aatgccagat 4500 caatccggac actgcaggac tccttcacgc atcttacgga tgcctgaact gagccaattg 4560 ttaggtatat ctcgttcgac aatttacgaa aaaatgaatc cgttatcgaa atactacgat 4620 gcaaccttcc ccaggccggt acgtcttggt agtggttctg tgggctggcg ttcatcagct 4680 attgacgaat ggcttacttt acatactgta cctgccagat cagcagtcaa aggtgttaat 4740 gacgaagtga gacatacgct ttcttcagat atgaccatga gcagataagt ttttgtcatc 4800 acgtgatcac ctcaggagga aaaagaagca taagaacaat ttagccagaa gtttaattga 4860 taaacagaat ttccagcatt cattgttgaa agagcagcta ttgtcgctat tgtagcggta 4920 attgctgcta taaccgaaac gtattacgaa aaaggaagca tttatgcctt acatcaaacc 4980 ggatatgtcg tattcagtat atgcatgacc atcaatgata gggaaggcaa taattaaagc 5040 tcaatacaat aaacaagtac ctctgactct ggttgcaatg tcagtattaa cagcgatgtc 5100 aattgcctgt cagaatcagg ttgacgtatg cagtcccgga aatttacgtg gggccgttaa 5160 tatttacact atggttctgg agaaagggaa aagaccgggg gaaaggtatt agtgaaataa 5220 tttccggagg tattaagaat gagaaatatg aatgatattt cgtggtgaat aatacagtct 5280 tcactgaatt aaccttatcg gtttattaaa catcagatct acaaatgctc tgtatttctc 5340 agagcatcag gtctgaatag cagctatttt cgctattgta gcgggatttg ctgctatttt 5400 actaacccat taatgaaaag agaggctttt atgtgcttac ttgcaccaga aaatccttat 5460 ccgatatatg cactaccacc gctggtgaga aatgcaataa ttgaaactca aaaaaataca 5520 caggcacctt tggctatggt ggcaacatcc gcattaacag cgatctcaat tgcctgtcag 5580 aatcagattg acgtgtgcag acctggaaat ttacatgggc ctgttaatct ttactctctg 5640 attctggctg attccggtga aaggaaaacg accgtggata aagtgtttat gaaagcattt 5700 tatctcaggg atgaagccct ggcggatgaa tacgcgaaac tggttgagaa ttacagtaca 5760 gaaaaggaaa tatgggagca aaaacaaaaa gcgctggaat caaaatttca taaagagatt 5820 cgtgccggta aagattacaa ggcaacagaa tcagagcttg aaacgcatct gaataaacct 5880 cctgttccgc cgcagatacg tcgaacaatt tttaatgaga caacgataga gggaatgtta 5940 aaatattact ccgatagcaa tcgctctttt gctcttgtat ccagtgaagg gggggtaatt 6000 tttgacagcc gggccatgag taaactggga attattaaca ctttgtggga tggaggttct 6060 cttttcatcg acaggaaatc atctcccgga attaatttga aggagccaag actgacgata 6120 tcggtgatga ttcagcctga tgtttaccac aaaggttttt gtacgcgaaa aaaagaaatt 6180 gtgaaaacgt caggacatca tgcaaggttt ttgatgtgtc aaccaacatc aacgcagggg 6240 acaaggataa tgatcaatga gcttattgat gaaagtctgg cgatgagtgg tgaacgacgt 6300 tgccttcact tttctcctca ggctgccaga atctggacgg attattacaa tgatgtggaa 6360 tcgaagctgg ggggattggg gcctttaaga cattgccggg aatatgctgc taaaaatgca 6420 gagtatatgg caagactggc aggacttatt taccattcga gcggtgaaga gggggagatt 6480 tccccttaca ctgcagaaat ggcgagagaa ttagcaatat ggtacggtaa tgagtatgtg 6540 cggttgtcta atccgttaac ttttgacaac tctgccctga ccgtacctgt gcgactcatt 6600 ccagaggagc ttgaactttt caactggata aaaagctatt gtattgagaa ggggatcctc 6660 tgtatgaaaa aaaatgacat tttacagcgt ggtccgaacc gtttccggaa aaaggataaa 6720 atcaactggt tactggattt actgtatgaa caaaacagag ttgtaccggt tattgaggga 6780 aaaacgttgt gtgtcgcacc taactttgac ctctgaacga cttaatcgtt gagtacatat 6840 agtttcctct gctacttgcg gaggagacta atgtctttac catgtcagcg ttgtattaga 6900 aaactctggt acaggtcagt cagtaaatat aactggtgta accactattt actattggat 6960 agagtgttgc tcaggatatt gtcggcttta gtctgaggtg aggtggggcc ttcattgttt 7020 tcgtgttcaa taaataattt aggttaatta gtattattag tggaagttat gtgatctgtt 7080 atgttgtctt gtacgcactt aacactggtt acgtaccgga acactattag agtatgttat 7140 ggctctgtta cagtttatag gtatgaaaaa atataatctt tcctgtatga aataatattc 7200 ttatggtgtg tggggtatgg tctgtatacc atcattttta tggtgaagtt aaatatctgt 7260 agaggcctta agctgggtcg ctgtttttac ttaatggtac agaagtatta atagcggtgt 7320 tgcctgtggc tacccgatac tggcttttgt gaatgtcaga ttacttcctg taagtgattg 7380 aatggtactt ccttaaactc aattctatga ggtgtgtttt taccattgta attcgtactg 7440 gtcctcagtt taagtgagtc ttactgtact ctgaaatatt acctctttgg agtaatgagg 7500 taatacgaaa cagttttatc aggttgtctg tgctgctggt tacctcgttt attaatgccg 7560 cggtacggcg tttctgtact ctcagtattt atgtaattcc accttcctgt aacttttata 7620 aagtaaggac tataaaatgt ataatgctaa tcccaattac gaaatggact tcatgattct 7680 gaaagacgtg aatgaacaca tggaaggtct gtttcaacgt ttttctaaac tgttaccttt 7740 cagaattgat tttgcctaca ggaaagacac gcccagtttt ggtcattcct gtaggcacag 7800 tatgtgtatt gaaatgcacc gcttacttag tgaaacccaa acgatgctgg cgggatatta 7860 ctgggtaatg gaatatacgt caaacaaggg acttcatatt cattttatcg gctacctgga 7920 tgggcaacgt cacaacaaat cttatcggat atccaggcaa ctgggagata tctggaggcg 7980 gatcacggaa ggggagggtt attttcacct gtgcagggct aaagacaaat acccggtgcg 8040 tatcgatcac gtaattcact atagtgataa atctgcggta gacgacttac gttacgccct 8100 tagctatctg gccaaacagg atcagaaaga acacggtatt attctgaggc gtagcaggct 8160 tcccgaaaaa agtaaccggg gccgaccacg acataactga attacagctg tattaggtat 8220 tagaattaag tttctgtaag ttgttgggag gtgcttgagt taataggcag aagagggcgg 8280 ggcgctttgt catcagtgta ggggacccga atttctgccg tggtgcctca gtggatcgga 8340 tacaggtaac gaatatggtt cataaatctg acagtgatga attagctgca ttgagggcag 8400 aaaatgcccg tctggtctca ttacttgaag ctcatgggat tgaatggcga cgtaaaccgc 8460 agactcctgt gcagcgcgtt tctgtattat ccaccgacga gaaggttgca ttatttcgtc 8520 ggttgtttcg tgggcgtgat gatgtatggg cacttagatg ggaaagtaaa accagcggca 8580 aatcagggta ctctcctgcc tgcgctaacg aatggcaggc gagaatatgc ggtaaacccc 8640 ggataaaatg tggggactgc gctcaccgtc agttgattcc tgtatccgat ctcgtcatct 8700 accaccatct ggccggtacc catactgtcg ggatgtatcc gttgctggaa gatgattcct 8760 gttattttct ggcagttgat tttgatgaag ctgaatggca gaaggatgca tccgcattca 8820 tgcgatcctg tgatgagctg ggtgtacctg ctgcgctgga aatatcccgt tcacgtcagg 8880 gggcgcatgt ctggatattt tttgcctcac gagtttcggc ccgcgaagct cgccgtctgg 8940 ggactgctat tattagctat acgtgtagtc ggacccgaca gctgcgattg gggtcttatg 9000 accgattatt tcctaatcag gatactatgc caaaaggggg atttggtaat ctcatagcgt 9060 tacctctgca aaaaagaccg cgtgaattgg ggggaagcgt ttttgttgat atgaatctcc 9120 agccttatcc tgatcagtgg gcttttcttg tatcggtgac cccgatgaat gtgcaggata 9180 ttgaaccgac gatattacgg gctacaggga gtatccatcc tctggatgtg aattttatca 9240 acgaagaaga cctgggtacg ccgtgggaag agaaaaaatc atcaggaaac agactgaata 9300 tttctattgc agaaccgctg aaaatcacgc tggcaaacca gatctatttc gaaaaagcgc 9360 aattacctca ggtgctgatt aaccgactta ttcggctggc agcatttccg aaccctgagt 9420 tttataaggc tcaggcaatg cgtatgtcag tctggaataa gccccgtgtt ataggttgtg 9480 cggagaatta cccgcaacac attgcgttgc cccggggatg tctggacagc gtattatctt 9540 tccttaggga caacaatatt gctgcagaat taatcgataa acgatttgcc gggacggaat 9600 gtaatgccgt ttttatggga aacctcagag cggagcagga agaggccgtt tcggcattac 9660 tccgttatga cactggtgtg ctttgtgcgc caacggcttt tggtaagaca gttaccgcag 9720 cggcagtgat tgccaagcgg aaagtgaata cactgatact ggtacaccgg actgaattgc 9780 tgaagcagtg gcaggagcgt ctcgcggtgt ttctgcaggc cggtgacagt attggtatta 9840 tcgggggagg taaacataaa ccctgtggca atattgatat tgcggtggtg cagtccatat 9900 ccagacaagg agaagttgaa cctctggtca ggaattatgg gcaaatcatt gtggatgagt 9960 gccatcatat tggcgcggtt tcattttctg cgattctgaa ggaaacgaat gccagatatc 1002 0 tgcttggcct gacggcaaca ccaatccgac gggatggtct gcatcccatt atttttatgt 1008 0 actgtggtgc cattcgccat acagcggtcc gcccgaagga aagcccacat aatctggagg 1014 0 tactgatccg ttcccgtttt acatctggtc atttaccatc ggatgcgaga atccaggata 1020 0 ttttcagaga aattgctctg gatcatgaca gaacggtggc gatagctgaa gaagccatga 1026 0 aagctttcgg gcaggggcga aaagttctgg tactgactga acgtacagat catctggatg 1032 0 agatagcatc agtgatgaat tcactgaaat tgtctccctt tattctccat ggtcgactat 1038 0 cgaaaaaaaa gcgtgcgatg ctgatatccg ggctgaatgc tcttcctccc gattctcctc 1044 0 gaattttgtt gtcaacaggc agacttattg gtgagggatt tgaccaccct ccgctggata 1050 0 cgctgattct tgccatgcct gtgtcatgga aagggacatt acagcagtat gcagggcgtc 1056 0 ttcacagaga gcataccggt aaaagcgatg tcaggatcat tgattttgtg gataccgcgt 1062 0 atcctgtgct gctcagaatg tgggataaac gtcagcgggg ttataaagcg atggggtaca 1068 0 ggattatagc tgacggcgat gaatcagtga tttaatttta aggagtactt tacccttttt 1074 0 aaataatttg agctccccgg gttgttcggg caacaaagag tcccagtata caggcttcag 1080 0 gaatatgttg tagtatcagg cttttcatcg ctttaaaatg actaccggca gtgagaacgt 1086 0 catcaaaaat aacaatctag ggcctgcacc cttccagtaa ttgttcatcc agttggtagt 1092 0 ttgccataat cgcttctggt aagggccggt ttgttgcggt atgagaggct attgttgata 1098 0 cgttttgcac aaccagttcc cagaaatcca gccatggttc gtaggtttgc gcaattcgca 1104 0 gaatttctgt catacggtca tcgtaagcgg catctgtacg gcatttggat ggtggtacgg 1110 0 gaacaaatgt gtattcctca agattaccga tatttgatat gagcatctga gcaacatact 1116 0 caatagcagc ctttttatag tggtaatcag gctacgaaag tacagcgttt tataaattgt 1122 0 ctcaggtgat attcgcagcg ttttttgacg tggttttgtt cgccttaacc atcctgatat 1128 0 ttgctctgga gaccatttca tctccagctt ttccagaaca agctttcgca atggtaaatt 1134 0 ttgatccagt aagcacggtt ttggcctttt cgccattctg ttggctcggt tattagcatc 1140 0 aacagctttg taatagcgtc tgccccgatt acgcgtaagc gtacagcgag ggccgtattg 1146 0 acggggatgt gttattcagc tggcagtgct atgcgccacg gaagcagttc gctgacccgg 1152 0 ttgaccggcc agtctgctat gacgccaagc acatggcgaa ggtagctttc tggatccacg 1158 0 tcattcagtt tgcacgtccc gatcaggctg tacagtagcg ctccccgctc accaccatga 1164 0 tcagagccga agaacaggaa gtttttacga cccagactga ccgcccgcag ggcattttca 1170 0 gcgatgttgt tgtcgatttc cacccagcca tcgttcgcat agtacgtcag tgccggccac 1176 0 tggttaagtg cgtacgcgaa cgccttcgcc aactctgagt gtcgcgacag ggtcttcatc 1182 0 ttttcacgca accagctttc cagggatttc aacaacggtt tcgtttttcg ctgacgttca 1188 0 gcaagccgct gctctgccgg cattcccctt atatccgcct ctatggcgta caactgaccg 1194 0 atctgctcca gggcttcttc cgtcagtgct gacgggatgc ggacgtgcac atcgtggatc 1200 0 tttcggcggg catgagccca gcaggcagct tccgttatcc caccattgcg atacagctcg 1206 0 ttgaacccgg cgtacgcatc cgcttgcagc acaccgctga agcaggcaag atgagtctgc 1212 0 ggatggatgc cttttctgtc cgggctgtaa gcgaaccaca ctgcaggtgc caacgctgac 1218 0 cctgcattgc ggtcatcacg aacatacgcc cacaaccgcc cggtcttcgt cttcttatta 1224 0 cccggcagca gtacctggac cggggtatca tcggcatgga gtttgccgtc agtcatgaca 1230 0 tagccatgaa gcgcctcttc cagcggagac agcagccggc agcatgcatc cacccagccc 1236 0 gacagcagtg aacgcctcag ctccacacct tgccggccgt atatttctga ctggcgatac 1242 0 agcggggtgt gctctgcata cttcgaggtc agcacgcggg ccagcagccc cggtccggcg 1248 0 ataccccgct cgatgggccg cgaaggtgca ggtgcctgca cgatggcatc gcactgagta 1254 0 caggcatgtt tttcccgtac cgtccggata acccggaagg cgctacgcat caactccagc 1260 0 tgttcggcgg tatcctcgcc cagatagctc agtgaaccgc cgcagttcgg gcagcacggc 1266 0 gccgcaggca acagtcgctt ttcgtcacgg ggtagtgatt cagggaacgg cttacgggtg 1272 0 cgggtctgac gcaacggacg ctgtactgcc gggtcataca ccctaccagt cagcgtatcg 1278 0 ctctctttct gaagccggtt cagatcggct tccatttgtg cgatacggcg ggagactttt 1284 0 tcggaacgac tgccgaagtt catccggcgg agtttatcca gctgcgcctg cagatggtct 1290 0 atttcgcgct cccggttgct cagcttttcc tgcagggcgt ggatcagcgc ttcctgttcg 1296 0 gccaggcgct gtttcagcag gaagatgtcg tcagaagaga tgtcgttcat aagctcgtat 1302 0 tttaccgggc ttattctgtg acaaccagga taaagagatt tacagcatgg tcagggaggt 1308 0 cagcagccgc ttaggctgtc gccagtcgat accttccagc agcatcgcca gctgcgcctg 1314 0 cgtaaggaac actttgccat cacgggctga cggccaggcg aagcgcccac gctccagccg 1320 0 tttggtcagg aggcacagtc cgtcaccggt ggaccacagc agtttaacct gactgccgct 1326 0 gcggccccgg aaaatgaaaa catggccgga catgggatcg tctttcagcg ccgtttgtac 1332 0 tttcgcagcc aggccgttga agccatttct catatcggtg ataccggcaa ccagccaaat 1338 0 tttggtcccg gaaggtaacg ggatcatcgc ttcagttcct gtatcagcag agtcaggagc 1344 0 ttttcgctga cattgccatt gaagcggagc gtcccgtgcc ggaacgttac ctcacagctg 1350 0 atactgaggg gttccgggtc ctctgcgagc gattctggct gttcggcagc tgcatcgaga 1356 0 gtcacaggaa gtagctgggg gctctctgaa gaaggtaata gcagctttcc ctcgcgccat 1362 0 tgttgtcgcc atttgaacaa cagattggcg ttaatgccat tttcaagagc aagttttgag 1368 0 atggatatcc cgggttcaca ggaggcagca acgagctgct gtttaaattc gggaggataa 1374 0 ttagggcagc cttttcgcct gccgggagtc acatttttct gcatatctga tactttggtt 1380 0 cccactactt atttggtgga caccactttg tctaattcgt cagattctga ccagacggtt 1386 0 caggctgtac gcttacgatt acgctgaact tcacgtgaga tcgtcgaagg actgcgattc 1392 0 agcgcagtag ctatcgcacg aatgctcatt ttggctgaca aaccagctcg tatctcctcg 1398 0 cgctcagaca gtgtcaggtg agctacagcc cgcttacgct catggggttt tatgccgcca 1404 0 gtatccctta acatagtgaa gatcgttccg ggttttgaac ccaggatatt cgctatttca 1410 0 ctgaagcctg ttccgttctt ccatagttca aaaacagagg ctttttcctc tgctgtaaat 1416 0 gttcgtctca ttcaaaaaac ctccgcaacc ccatgttttc acataactgt tgcgttgacc 1422 0 aattgaatct acaacagcgt attttgcaca ggagtcgctg aaaaatacgc gttaatcgaa 1428 0 caatggcgac aacaatttcc cattgaagcg atgtgtcagg tatttggtgt atccaggagc 1434 0 ggttattaca actgggtaca gcatgaaccc tcagacagaa aacaaagtga tgagcggcta 1440 0 aaactggaga ttaaggtggc acatatccgc actcgcgaaa catatggaac ccggcggctc 1446 0 cagacggagc tggcagagaa tggcatcatc gttggtcgtg accgactggc acgtcttcgt 1452 0 aaggagctaa ggctacgctg taagcagaaa cgcaagttca gggcgactac gaactcgaac 1458 0 cacaatctgc cagttgcgcc aaatctgctg aaccagacgt tcgctcctac agcaccaaat 1464 0 caggtctggg tggcggacct gacgtatgtt gccacacagg agggatggtt gtacctcgct 1470 0 ggcatcaaag atgtttatac gtgcgaaatt gtcggctacg ccatgggaga gcgcatgaca 1476 0 aaagagctga caggtaaagc cctgtttatg gcgctcagga gccagcgccc acctgccggg 1482 0 ctaatccacc actctgatcg aggttcacag tactgcgcat acgattaccg ggtcatacag 1488 0 gagcagtttg gtctgaaaac atcaatgtcg cgtaaaggta actgttacga caacgctccg 1494 0 atggaaagct tctggggaac gctgaaaaat gagagcctga gccactatcg ttttaagagc 1500 0 cgggatgagg ccatctcagt aatacgggaa tacattgaga ttttctacaa tcgtcagcgt 1506 0 cgtcactctc gtctggggaa tatctccccg gcagccttca gggaaaaata tcatcagatg 1512 0 gctgcttaaa aaaagaacaa atggtagtgt ccgctattgt cagtacacct caaccatctg 1518 0 gcttgaacct gcgagcgaac gcaccgtttt cctgcagatc aaaaacacgt cggataaaga 1524 0 catgagtgga ctacagggaa aaattgccga tgcagtcaaa gccagaggtt atcagatcat 1530 0 gacttccccg gataaagctt actactggat ccaggctaac gttctcaaag cagacaaaat 1536 0 ggatctgcgt gaatctcagg gatggctgag tcgcggttat gaaggtgcag cagtcggagc 1542 0 tgctcttgga ggtggaatca cagcgtacaa taccgggtcg gcaggtacca ctctcggtgt 1548 0 tggactggct accggtctga ttggcatggc cgcggatgca atggtggaag atataaatta 1554 0 cacaatgatt acagatgttc agattgccga gcgaaccaga accagcgtca gaacggataa 1560 0 tgttgcagct ttgcgtcagg gaacatcagg ctccaaaatt cagacaagca cagaaaccgg 1566 0 caaccagcat aaataccaga cccgggttgt atccagtgcc aaccaggtta atctgaagtt 1572 0 tgaagaagct aaacctcatc tggaagacca gctggcaaaa tcaatcgcca atatactctg 1578 0 atataaatat cccggtggcc attcacctgg cctccggccc tcttagtctc aacgttcaga 1584 0 caattcagat attattttcc ctgtcacacc atatacccat gccggaacag aatctaatga 1590 0 cggtaccagt aaattcttca gcgttcggtt tgcctgacgc ccgtagctgt atttgtgtct 1596 0 gtttcttctt atacaagagc agtagtacaa tttctcttcc agagtcagtt caactttagg 1602 0 acgtaaccaa taaagatctc ttccactata aaatggtgaa tcctgtacaa acgattccat 1608 0 aacagaacct cctgctgcta cagttaacac agctgctggc atggactaat accatctttt 1614 0 aatttaaccc tggcggagac gccattattt ttggacgttc ttgaaacaaa attaattcct 1620 0 gaagaatctt tctccagttt attcagctca agattcagtc cataattaac gtcaaataac 1626 0 tctgataaag gtatcagttt atgttcagga taatgattat cccgacgaca acaaatatta 1632 0 aaatcctgca tattacccga catcaggagt tcaaaaccgt ccccggcatc attcatactg 1638 0 gcagataaat tcattaccca gtttagtgct aatcaacagg tacggcttaa cttacaggaa 1644 0 ttccccggga ggggcggact catcctcagt tagcggcaaa atcgcatcac agccaatcgc 1650 0 ctgtctcgat tccccatcgg cgaacaatgt atgtggccac aaaatcctgg ctggctcaga 1656 0 acgaagagca tctgagcaaa gaggtcatca atctggtatg aatatctggc agaaaatatc 1662 0 ccctgaatcc acaactgctg tgcatatctg ctcaaatcag catcaatcat aaaccagtaa 1668 0 tcacagtgcc tgtgattggg ttacaggaat aagtccccct tcataaggca tatcatcaat 1674 0 accggtgaag gaaaagaaag catcagatgg cctgatagtc tgcgtcagtc aatgacatca 1680 0 gtgctttatc cggaacaatg tatccatgtt ggcgacagag aaagccattg ccatgaacag 1686 0 ttttgtttat ccccggaaag tcatttctgt tacaaattta tattgacaaa cttgctttcg 1692 0 atgagaaaca tactatttca atgaaatgca gaatgaggca aaatttcgtt atgtttttta 1698 0 attcccgaaa gaataaatgt ggcttattac aaaatcctgt taatgttaac tgatatttta 1704 0 taatgcatat tcagacatat aattaaataa gaggtattta tggctaatac gaccactggt 1710 0 gttaccagaa ttattaaagc agcgggttat tcatggaaag gcttatgtgc ggcatggcgc 1716 0 tatgaagcag cctttcgtca ggagtgcatt ctggttctgt cagcactgat aatatccttt 1722 0 tggctggatg ttgactctgt tactcgagta ttactcattg gttcggcaat gatggtaatt 1728 0 attgttgaaa taattaacag tgcaattgaa gcagttgttg acagaattgg ttcagaacat 1734 0 cacgaattat caggcagagc aaaagatatg ggttcagccg cagtgttgat tacgatttta 1740 0 gttgctatca ttatatgggg agttttatta ctttcataac gcccaacatc taaattattc 1746 0 acagttacct ggttaatatt tacttaagga taagaggtat tcacctctta tcctcagaaa 1752 0 aatgtcagta tctatctgca ggaggatata atatcatctt ctttattata aactgaagta 1758 0 tttacattcc ataaccccag taacgatgaa aatatattat catgacttac tgttctgttt 1764 0 agagcatgtt ctgacaaaca attcaaatca atttttttag aggaaacgaa ccccggagac 1770 0 atccaggtaa taagaggcac atgcgtttgc tcagctggag caacattata tggtgttcca 1776 0 tgtaagtata atccattttc tcccagagat tctccatggt cagagacata taataaaaca 1782 0 gtatcatact catctttata ttcgataagc ttgtcaatta attttgatat tatataatca 1788 0 gtatagcgaa ttgtattatc ataggtatta atcaattgct catgcgtaca attttcgata 1794 0 tcactacgat cacatgttgg tttaaaatat ttatgtgact caggataacg gagatagtag 1800 0 gtaggaccat gactacccat caaatgaaat acgataagtt tatcctctga gttattattt 1806 0 atatactcat caatattttt tagcataacc tcatcataac atgagttttt cttgcataat 1812 0 gtattatctg aatttgatgg ctcaatatta attgtaggga ttcgcttaca tacaccttta 1818 0 catcccccgt cattttcaat ccagagtaaa tttacccccg ttctgtacag aatatccagt 1824 0 acattttccg aatttaccgc tttgcgggaa ttgaactctt ttcgcttcat atctgaaaac 1830 0 atgcatggaa cagatatggc tgtggatgtg ccacacgact gcacattatg aaaggatata 1836 0 agttcattat atttctttgt aaaatcattg gtaccacgag aatatccatt cagagcatag 1842 0 ttttgacttc ttgctgtctc cccgacaact aaaaacataa ttaccggctt ttgtttttca 1848 0 tttattgtgc gggatgcatc cgttccagtc tgacgaaact cgccaggaga aacaaaaaaa 1854 0 tcccttacat atttaaaccc actgtagata taattagtag gtattatttc tttatttaat 1860 0 gaagagttgt ttctgccaac tgatgcataa tccttataaa agaaaaacgc aatcgcaaat 1866 0 ataatcaaga gagatgcaaa cattgatatt aaacgatatg taataccctt tatccatgtc 1872 0 tcaggataac ggatatttac taacaacaat agtccacatg gaagtatacc cgtaaataaa 1878 0 aaccacagta caacagacat attgaaatat gatgtcattt cacctgcatt tgtttcaaaa 1884 0 atattctgca tcattgtttt atcaaactgc acaccatatt tcatggtggc atatgtaaca 1890 0 atggaactac agataaacag aatacaaaaa aaaggtttaa atatatacct gaatgagaac 1896 0 ggtgtaaaaa caaaatttaa tgcagatatc agaaagactg gaagagatat aataaatcca 1902 0 agtttcacac catcaaggtt attaataata ttaaacagat gcatccagac agggatattg 1908 0 aacaatgtgg caaaaacaac atctatcatt aacatcaaga aaagaaaatt aatactgatt 1914 0 tttttaatca tcttaccccc attaattaga gcctataatt gtccgtatct aaaagtgata 1920 0 tatttttata aaacctggta aagtgaatac tgatttatac caggtcaaac ttcaacttca 1926 0 tcatcaaaac tttatgtcaa taaaggcgtt tatagttact gattctttta ttttacaaca 1932 0 ccactaacat ctttttaata aaaaatatgt tcacaatagc atacacagaa attctctaag 1938 0 gtattatatc atcaggaaat attattattc cattcatctc tggaggcccc ccctcgatat 1944 0 gaaaaacgat atcacacaga agccctgccg tgtacagata aactgtttgc agaccagtca 1950 0 gtgactcagg agcgacgtcc gcaacaaatg tatggactgt atcacagatg ctctccccgt 1956 0 atgactgaag acaggcatgc atgaaaatac tgtcgcttcc ccaagaaaag gggaaattat 1962 0 catctgcatg acccgaccag tgctcagtca tgaacactct gtttcagtga gcagtttccg 1968 0 cattaatgaa tctgtcatac tgctattgta tcagcaagtt atccccataa caccttgata 1974 0 tcattctgag ccagatggca taatcacagc ccattgtcgg atctttctgc ctgattctct 1980 0 ggataatccc gacaatatgc attgcttttc tggcgatgta tagccccggg agccggaacg 1986 0 cttcatgacg aaaacaaaca ttcgtattat tcagacgaaa actcactgga aaggcatcat 1992 0 cttttatata acaaggaaat ccggctcttt actgtcgttt tatctttatt tatcaggggc 1998 0 gtaagattgc tcagtaccgc gttaccacaa aataaaaaag gctggcaggc catgctggat 2004 0 ctccgttttc agcgtctgca cgggaaaacc acgctcacca cccgtcatca tgtcggtctg 2010 0 ctcactgttc agcgtccttt ttatcccgaa gaagaaacct gccacctctg tctgcttcat 2016 0 ccacccggtg gtatcgtcgg cggtgacgaa ctcatcatca acgcaataat tgactctgat 2022 0 tgccatacgc tgatcaccat gcctggtgcc agtaaatttt accgcagcag cggcgcgcag 2028 0 gcgcaccttc agcaaaacct gacgctgtgc aataacgcaa cgctggagtg gttgccacag 2034 0 gattcgattt tttttcccgg cgctcacgcc acgttgcata ccgtgtttca tctgtcgtcc 2040 0 tccagtacac tgctggcctg ggatcttctg tgccttggac gtccggtcat cggagaaacc 2046 0 ttcagccacg gaacactcgc taaccgtctg gagatatggg tcgacggttc tccgctgttg 2052 0 attgagcgtc tgcacgtggc caatggagaa cttacctgcg ttgcccggaa accatgggtg 2058 0 ggaacgatgc tgttctacct ggggaatgaa acgcaactgg aagacatacg cgaaaaactc 2064 0 acaccactgg aaaactacgc cggagccacg ctcaccgatg gtctactgac agttcgcttt 2070 0 ttaagtgatg ataatctgcg ttgccagtag gtaatgcgtg atatctggca atttatgcgg 2076 0 ccgcaactga ctgacaaatc accggtactt ccccggatct ggctgactta agagaacgct 2082 0 atggaactga ctccaagaga aaaagacaaa ctattactgt ttaccgctgc actgctggca 2088 0 gagcgtcgtc tggcccgcgg cctgaaactt aactatcccg aatccgtggc cctgattagc 2094 0 gcttttataa tggagggcgc tcgcgacggc aaaagcgtcg ctgcgctgat ggaagaagga 2100 0 cggcatgtcc tgagtcgcga gcaggtcatg gaaggcatac cagaaatgat ccccgatatc 2106 0 caggtcgaag ccacctttcc ggacggctcc aagctggtta ccgtccataa tccgataatc 2112 0 tgaggtaaca gatgatccct ggagaatata aggttaaacc tggctatata gagcttaaca 2118 0 tcggccgggc tacctgcagt attatcgttg aaaatcacgg agaccgacca attcaggtcg 2124 0 gttcccatta tcacttcgcg gaggttaacc cggcactgaa gttcgatcgc cagaaggcaa 2130 0 gaggctatcg tctcaatatc gccgccggaa ctgcagtgcg cttcgaacca ggccaaaagc 2136 0 gtgaggttga actggtggcg ctgagcggtg cccgtatcgt gcacggtttc cgcggagata 2142 0 taatgggtga gctggaggca aatgatgagt aatatttcac gccaggccta tgctgacatg 2148 0 ttcggcccta ccaccggtga taaaattcgt ctggcagaca ctgagctgtg gatcgaggtc 2154 0 gaagatgatt taactaccta cggcgaagag gtcaaattcg gcggcggtaa agtaatccgc 2160 0 gacggtatgg gacaggggca aatgctctcc gccggctgcg ctgatctggt gctgaccaat 2166 0 gccctgatca tcgattactg ggggatcgtt aaagccgata tcggcgtcaa agatggaagg 2172 0 atatttgcta tcggcaaagc cggtaatcct gatatacaac ccaacgtcac tatcccaatc 2178 0 ggcgtatcca cggaaattat tgccgcagaa ggcaggatcg ttaccgcagg tggcgtcgat 2184 0 acgcatattc actggatctg cccacagcag gctgaagaag cgctgacatc cggcattacc 2190 0 accatgatcg gtggcggtac tggcccgaca gcgggttcta acgccacaac ctgtacccca 2196 0 ggaccatggt acatttatca aatgctgcag gctgcagaca gcctgccggt caatatcggg 2202 0 ttgctgggta aaggcaattg ctccaatccg gatgcgcttc gtgagcaggt cgcggccggg 2208 0 gttatcggcc tcaaaattca cgaagactgg ggagctacac ctgcggtaat caactgcgca 2214 0 ctgactgtag ccgacgaaat ggacgttcag gttgcgctac acagtgatac gcttaacgaa 2220 0 tcaggattcg ttgaggatac tctgactgcc atcggcgggc gcactatcca taccttccat 2226 0 acagaaggtg caggtggtgg tcatgctccg gatattatca ccgcctgcgc gcaccccaat 2232 0 attctgcctt cctcaaccaa tccgacgcta ccctataccg tcaacactat tgatgagcat 2238 0 ctggacatgc tgatggtttg ccatcatctt gacccggata tcgccgagga cgtagccttt 2244 0 gccgaatcgc gcattcgcca ggaaaccatt gccgcggaag acgtcctgca cgaccttggc 2250 0 gcgttctccc tcacctcgtc cgattcgcag gccatgggac gcgtcggaga agtagtgtta 2256 0 cgaacctggc aggtggcaca ccggatgaaa gttcagcgcg gcccgttacc ggaagaaagt 2262 0 ggtgataacg acaacgtccg cgtgaagcgc tatatcgcta aatacaccat taatccggca 2268 0 ttaacccacg gtattgctca tgaagtcggc tcgattgaag tgggaaaact ggcggatctg 2274 0 gtgctctggt ccccggcgtt ctttggcgta aaaccggcga ctatcgtcaa aggcggaatg 2280 0 atagccatgg cgccgatggg tgatatcaac ggctctatcc ccacaccgca gccggtgcac 2286 0 tatcgcccaa tgttcgctgc attgggcagt gcccgtcacc gctgtcgtgt gactttcctg 2292 0 tcgcaggcag cagcagcaaa tggcgtcgct gaacagctta acctgcacag cacaactgct 2298 0 gtggtaaaag gctgccgcac agtacaaaaa gccgatatgc gccacaacag cctgttgcct 2304 0 gatataaccg tggattcaca aacctacgaa gtgcgtatca acggcgaact gataaccagt 2310 0 gaaccggcgg acattctgcc aatggcgcaa cgttatttcc tgttttaagg agcacaaatg 2316 0 ctttatttga cccggcgggt ggagaccccg gctcagacaa ctgccagcgt taccctccct 2322 0 gttgacatgc gggtaaaaag ccgtattaaa gtcaccctta acgatggacg tcaggctgga 2328 0 ctgttgctgc cacgcggtct gctgctgcgc gatggtgata ttctcagtaa cgaaaacggt 2334 0 gatgaattca ttaaggtgat cgccgctgat gaagccgttt ctgtagtgcg ctgcgcagat 2340 0 ccttttatgc tcgcgaaagc ctgctggcat ctcggcaatc gccacgttcc gctgcaaata 2346 0 atgcccggag agctgcgcta ccatcacgat cacgtcctcg atgatatgct gcgccagttt 2352 0 gggctggatg ttgattttgc acatcttccg tttgagccgg aagccggcgc ttacgccagc 2358 0 aagtcgcacg cccataatca cgatcaggag cacagccact gaatgccgac tccggaaaaa 2364 0 cgtctgcggc tgatgcagct tgccagtaac agcctccctg ttggaggcta cagctggtcc 2370 0 cagggactgg agtgggcagt ggaagcaggc tgggtagaag atagcgccgc ctttgaacac 2376 0 tggcagcagt tgcagatgga acagagtttt tttgccgtcg acctgccact gcttgcccgg 2382 0 ctataccggg cctgtgaagc gggcgatcct gacagtgccg ggcgctggac cgcttatctg 2388 0 ctggcctgca gggaaacccg tgagctacgc gatgaagaac gtaaccgcgg tgcagccttc 2394 0 accagacttc tggtcgactg gcagcccgac tgcccggccg aatggcgcaa actatgccag 2400 0 caaagccagt taaccggtat ggcatggctc ggcgtacgct ggcaaatatc cgtttcagac 2406 0 ctggccctga gccttggcta cagctggatt gaaagcgcag tgatggcggg cgtcaggctg 2412 0 gtaccctacg gccagctggc tgcccagcag ttaattatgc gcctgtgtgc ccgctatgcg 2418 0 gcgaacatgg acagtgccct tgcaaccccg gatcacgcaa ttggttcagc aacgccactt 2424 0 gcatctatcg cttccgcgcg acatgaaacc cagtattccc gattattccg ttcttaggag 2430 0 aaaataaaat gaacataatc aagcaaccgc tgcgtgtcgg cgtcggcggt ccggtcggct 2436 0 caggtaaaac cgcgcttctg gaagccctct gcaaatccat gcgtgacacc tggcaattag 2442 0 ccgtagtcac caacgacatc tacaccagag aagatcaacg cattctcact gaggccggag 2448 0 cactggaagc ggaacgcatt gtcggtgtcg aaacgggggg ctgccctcat acagccattc 2454 0 gtgaagacgc atcaatgaat ctggcagccg tggaagcact gagtgagaaa tttggtaatc 2460 0 tcgagctgat ctttgtggaa agcggcggcg acaacctgag tgcgaccttc agccccgaac 2466 0 tggcggacct taccatatat gtcatagatg tggcagaagg agaaaagatc ccgcgtaaag 2472 0 gcggtccggg gatcaccaaa tccgacttcc tcgtgatcaa taaaactgac cttgcaccat 2478 0 acgtgggcgc ctccctcgag gtaatggagc gtgatacttt acgtatgcgc ggagaacgcc 2484 0 catgggggtt cactaacctg aaaagtggtg aaggtctgca aaacatcatc gcctttatcg 2490 0 aagagcaggg catgctgggt aagtaatcac aacatcctct gtatcagggc cggcaggcgg 2496 0 ccccttgttt ttatcagaag gaataacgga agttggcgtt caccgcgtta tccacgttgt 2502 0 acttaccaga tgccgatttt tcaaactcca gaccgaagcg gatgttgtcg cgaatttccg 2508 0 cattcaggcc aacattcatg agcatacgac cgtctttttc acccttgatg cgtttttcgc 2514 0 cggatgcatc acgcagtacg gtttcaccgt tagccagcag gtcaaactga taaccgatac 2520 0 cgtcgcgggc agtgaaagag ataattgaaa ggggtgttgc attgacagat tgaatctaca 2526 0 gctgcttttt ttaatatatc tcgctcaagg cgagcttcat ttaacgcctt acgcagttgc 2532 0 agaatttcag attccagttc agccaccgtg cgggaaccag gagtaccgag cccttttctg 2538 0 gcggcggtaa cccattgtcc taaagtgcct tcaggaagag ataatcggga agcgccttca 2544 0 ctgatcgaaa gttgattttc aagaaccgtt ctgacagctt cggctttgaa ctctttagag 2550 0 taacgttggg tttttctgct cattattagc tccttctgat gccattctat ttcaggaagg 2556 0 agtgtccgtt aaactcaggc tacctcaggt ttcactcatc tgggttttta cttccagatt 2562 0 tcgttttttg atcgctgtgc ccatggctcc acatcctgaa agagccagcg cagagctgac 2568 0 cagtgcaatc atcataactt ttttggtttt catttaatgc ccttcttatc cgacaggttt 2574 0 atggaagaca gagaaaccgc ctttacggta tattttttca gcgggcttct caagtatgtt 2580 0 aaaggataca ggtaaaaaca gcgggatcag atacgtcggg taaacgttta tttcataaga 2586 0 agtttttagg tcagaataaa ataatgggtg ttgttatatt atcagatgat gatttatgtg 2592 0 agcgcgttac ggatattgca catgaggtta aaggagagag caagcctccg caacggctcg 2598 0 cttcttattt aatggatttt ttcgggaagt ccagtttata attatataac atattgtaat 2604 0 actgaaagag agtgaggtta taagaacaga cagttgaatc tgaccgtctg aatatgtacc 2610 0 tttatgcgga attttcactt aaagggggaa aactgttgtg aaaccgaata tccatccgga 2616 0 ataccgtaca gtagtatttc acgataccag tattgatgag tacttcagga tcggttcgac 2622 0 gatcaaaact gaccgggtaa ttgaactgga tggtgtaact tacccatatg ttacaattga 2628 0 cgtttcttct aagtcgcatc cgttttatac aggtaaactg agaactgtcg cttcagaagg 2634 0 taatgttgca cgctttaccc agcgttttgg gcgttttgtt gatgcgaaaa aaggtggctg 2640 0 attttgccgc cagggtgcgt ttgacaattt aaaaacgcac cagacagaga gatcctgcac 2646 0 ctgaatatac cgttagcccg tcccaccggg gcgtgtgcag atgatctcgt caccggaaga 2652 0 ttgcggacct ctctgaaaac cagtacatta cgcgcgggtg cctttcggct gacggctgga 2658 0 aggattacct gaaggccgga tgtggaaagg ccccgagtca acttaaacgt taacccgagg 2664 0 ccctgaccat ctaccttcag caagtggaag gttagcgcct ctctgtaaaa ggagcaagtg 2670 0 ctatgccgca aaaaacgatc attgtgggca tgttatgcct gaccatgttg ctgaccgtct 2676 0 gggtgttaca cgcatcaccg tgtgaattca gggtaagctt catgtggtcg gaaattgcgg 2682 0 cgttcttgca gtgtaaaccg taagaaaccg cagcggggac aacagtcccc gctatccggt 2688 0 tgccaaaggt tcggtcgaaa gtcgcaccct tgcacacaaa tcacaaagaa aaaacaaaag 2694 0 tccgcagtgt aaaaactgtg ggctttttta ttcgcatccc gaaagtgtgg taacagcgtg 2700 0 ggggcaccaa aaaaagcccc ataaaatggg gctgaagatt ctgtaaggaa tttcacagca 2706 0 atgagattcc tgctttctcc aaggatatac gtgtcttcag gctgaatcaa tgggggcgtg 2712 0 gctctgaatc cacctgcgat taaaacttgc acaatgccgg gagttgagtt agaaaagtac 2718 0 agggcgcgat atccggctta ttttgttgct gtgttttgcc tcgtgctgga tgtcgcgtcc 2724 0 accgtttttc tgatgattca tatgaaatgg tactttattg atttactgcc attctgattt 2730 0 gcctttttat gttcattatt gcggttgtca cttccagttt ctggtgatgt tttgataaaa 2736 0 gtgaaagaat aaaacgataa ttgcagaagg tattgctaaa actatacata tcattatata 2742 0 aacaagatga aaatgatata taccataaga ccagaaaaga ggttttttcc agaatgatat 2748 0 ggatgtgtat tttagtgtga ttgtttttgt caggtatatt gaacaaggaa gggccaggcc 2754 0 actgagtatc agaaataagt caacttttat cgatgcttct gttggtgtgt catatatcag 2760 0 atgcaatatg gatattataa tggggcacat tccccacagg atatttttga aatagaattt 2766 0 ccggttcata tgtttatgct cttttgtttt atctcgggaa ttgtctcttt ttttttattc 2772 0 ctgaacattt tcgttgttta ataaccatgg ggtattatga ttatccttta tttttgatat 2778 0 gtaattgtca atagtggatt tcgtttcatt attgtggtta tagtaatcat gaagagtgca 2784 0 aaacacatca tcttttattg tggcgattaa tggggggtgg gtgaggttaa aatataaaga 2790 0 acgattgctt agtgtcctga aatgaatttt ttcgccaatg accagatcgg tgtttattat 2796 0 attgtagcct atttcaatta tattgtttga tggcatgtgt aatacatata tgggatattt 2802 0 gttgtgtttt tctattgaat aataaataaa atcaggcaca gacgtctgtt ttagtttttt 2808 0 ttgcatcttt cttatatgtc gtgacattaa tatcattttc gagagaatga ataagagtct 2814 0 aaaaaagaga ttaaatacta tattcagtac tatcagagta acaaacaggc caactcccca 2820 0 tagttctgaa aatatattgt cattgtaaat atactggaat gtatatccgg ctgataaaaa 2826 0 tgccaatata tataacgcta tgtctgtttt gtttaggttt tttattagat cggttattat 2832 0 tgattttaag aataagatgg taataagacc agtgataacc cagaaaaaaa taacggaaaa 2838 0 ttccataatt atacctttat cgtgtttctg gggtggtaat ctatcattgt gctgatatgt 2844 0 gtgtaaatac atgcattatc tgtttcttat attcttttta tgaagttact gattaattta 2850 0 tattagaaca tcacattcat aatgaaatca acatgttcat atggttgggt tgacggcaga 2856 0 tttccctttt tgttaacctg tatttgcatt aactgtcgct tttgcgacca gccaatgttc 2862 0 cagcagtctg agagggacgc cttcgggtga ctgccagcca atgtttcagc aatctgagag 2868 0 aaacgccttc gggtgattgc aatatcctcg tagcctgaaa gaggatgcct ttatggtggt 2874 0 acatccgttt agcctctggg aacggatatc actacggtga ttgaggtacg ttgatttttc 2880 0 cttcggatta ccgtggtgct tccggacaac cggactactg tgtattcccg gcagactggc 2886 0 ataaaaacgc ctttaaaatc tgcgtcttaa gatattttct gactttccgc atgcgcttct 2892 0 tatgactgtg cgcacggcat aagaccattt gaaatttggt cgcttgcgtg tgcatgtgga 2898 0 gtttgaagct gtgcgggcgt cactttcgtc agcgttaaag ctgacaaagt gacgctcgca 2904 0 cgtctactca acgaacccgc ataaactggc tctttacgag atgtttttta acatttgaag 2910 0 aagtgaccag acgtgaacgt ttttttcaac ctcattctgt atcgtactgg cgcttctccg 2916 0 gactgactta ctgaaagctt cgtaccaaca gaatcgcatt gttttttaag gagttttatg 2922 0 tagtgagata ccgaatcggc gatatgtctg acaggcagat atatcggggg cgacctttaa 2928 0 aggtacagtt aattctgcgg tcggttagcc aaaccgactt gacaccccgc taaacctgaa 2934 0 ctgattgcgt taccctgacg cacaggtact cactcaccga aggaacgtaa ctacaaaccg 2940 0 tgtcgtcagt aatattccgg cgaactcata ttgacgcgtt tttcgggcgc atcatcagcg 2946 0 atgcatacga atgatcgcag tctgacgatg gttgatttat tctgttgcgc cggggcgacc 2952 0 gccaggctgg tatcggaggc gggttctgaa gaactgaggt attgttccgg cgaactcata 2958 0 ttgacgcatt tttcaggcga gccactggca gcgcatacga ttgatcaccg tctgacgatg 2964 0 gttgatttat tttgttgcac aggggcgacc gccaggctgg tatcggaggc gggttctgaa 2970 0 gaactgagtc gggtaattgc gtcaggtcgc gaagtactga cacgggtact gatggcaggt 2976 0 gatgaagtac agccccggga atggctccgg gctgattcag gttctgactc actgtcagcc 2982 0 cgcgtggtcg ctgctctggc tcatttcctg tcgtcaggcg ttcaactccc gactgcgggt 2988 0 tatggcccgc tgcacgaaca cctgatggca ggtatcactc acccggagaa ggtaaatccc 2994 0 tcaaggggca gcaactcttc cagtcggtct tccggccact ccggtagacg cgtcagaacg 3000 0 tctgtcagcc aggcatgcgg ctccagacca ttacgttttg ccgtttccag aaggctcatt 3006 0 atctgtgccg cgcggttccc ggccatcagt gaaccggcga ataaccatgc tttccgcccc 3012 0 atgaccaccg ggcggatagc acgctcgcag atattgttgt ccaggggcac ggctccgtca 3018 0 ctcaggaagc agctcagttc atcgcgccgg ttcaggatat aattaatcgc tttgtttagt 3024 0 ggtccgtcgg gcggacagca cggctcctgc tcttcaggcc aggcaaacag gtcattcact 3030 0 atcggccggg aataccgttg tcgccattgc cgtatttttt ccacaggacg ttcacggatg 3036 0 aacttctcaa tgcgataaag acccgcgatt tttctcagcg ccatggctgc acggggctcc 3042 0 ctgctggcct tatacagatt tgcgaaaccg cgccttgcgt ggctccagca acaggcagat 3048 0 gtaataccgg ggtcattatc cgccagagat ttgtacacgc tgtatccgtc actcaccagc 3054 0 gtaccgccac accagccctg cagccaggcc tcaggatatc tgagggcccg tccggtctgc 3060 0 gagtcaaaac agacgaccgg cggaccgctt ctttctcgta agcgtaaact gaccgccgta 3066 0 tgtagccatt aagccagtat tggtaacgta ggtgcccacc ttttcaacta gtggacacct 3072 0 gttatggaac agaaaatatt atcctcagaa ccccgcagat cattttcaaa tgagtttaaa 3078 0 cttcaaatgg ttaaactggc ttcacaacca ggagcctctg ttgcccgtat tgcccgggaa 3084 0 cacgatatca atgataacct cctgttcaaa tggctcaggc tctggcagaa cgaaaggcgt 3090 0 atatcgcggc gtcttccggt aacaacctct tctggcgctg gcgttgaatt attacctgtt 3096 0 gagataacgc ctgatgagca gaaagagcct atggcggctc ttactccgct tttatccact 3102 0 ccttcacaaa gcacagtcag tgccagttcc tgtaaagttg agttccgcca cggtaacatg 3108 0 acgctggaaa atccttcacc agagctgctc acggtgttga tccgtgaact gaccgggagg 3114 0 ggacgatgat ctcgctccca tcaggcactc gaatctggct ggttgccggc gttactgata 3120 0 tgcgtaaatc cttcaacggt ctgggagaac aggtacaaca tgtgctggat gagaacccct 3126 0 tctccggtca cctgtttatc tttcgcggcc gacggggtga cacgattaaa attctgtggg 3132 0 ctgatgctga tggtctgtgc ctgttcacca aacgtctgga ggaaggccag tttatctggc 3138 0 ctgcggtgcg tgacggtaag gtatccatta cccgctcgca gctggcaatg ctcctcgata 3144 0 aactggactg gcgtcagccc aaaacatccc gccttaatgc actgacaatg ttgtaaaaat 3150 0 gtcatggccg gattataaaa acggtcatga gtcggaaata cctcattcgt atcactgagc 3156 0 tggaaaggct gctctctgag caggctgaag ccctccgtca gaaagatcag caactgagtc 3162 0 tggttgaaga gacggaggcc ttcctgcgct ctgcactggc acgtgccgag gaaaagatcg 3168 0 aagaggagga gcgggaaata gaacatctga gggcccagat agaaaaactg cgccggatgt 3174 0 tgttcggtac ccgttctgaa aaactgcagc gtgaggttga acaggctgag gcccaactga 3180 0 aacaacgcga acaggaaagc gatcgttaca gtgggcgtga ggatgacccg caggttcccc 3186 0 gccagttgcg acagtcacgt catcgtcgtc cgttaccggc acatcttccc cgtgaaatac 3192 0 accgtctgga gcctgaagaa agttgttgcc cggagtgtgg cagtgagctg gattatctgg 3198 0 gggaagtcag tgctgagcag ctggaactgg tgagtagcgc cctgaaagtg atccgcactg 3204 0 ttcgggtaaa aaaagcctgt acaaaatgtg actgtatagt tgaagcgcca gcgccgtccc 3210 0 gcccgataga gcgcggcatc gcgggctccg gattacttgc ccgcgtgtta acgggaaaat 3216 0 actgcgaaca cctgccactg tatcgtcaga gtgaaatctt tgcccgccag ggcatcgaac 3222 0 tgagccgggc attactctcc aactgggttg acgcatgttg tcagttaatg actctgctga 3228 0 atgataccct gtaccgttac gtgatgaaca cccgcaaggt tcacactgac gacacaccag 3234 0 taaaagtgct ggcaccgggc agaaaaaagg caaaaacagg acgcatctgg acgtatgtcc 3240 0 gggatgaccg gaatgcgggc tcatcagagc caccggcggt ctggttcgcc tactcaccag 3246 0 acaggcaggg aaaacatccg gtacaacacc ttcgtccctt ccggggtatc ctgcaggcgg 3252 0 atgcgttcag cggttacgat cggctgttca gtgcagaacg tgaaggtggt gcactgacag 3258 0 aagttgcgtg ctgggcccat gcccggcgaa aaatccacga tgtatacatc agcagcaaaa 3264 0 gtgcgacggc agaagaagcc ctgaagcgaa tcagtgaact gtacgccatc gaggatgaaa 3270 0 tacggggatt accggagtca gagcgtcttg ccgtcaggca gcagcgaagc aaagtgttac 3276 0 tgacgtcact gcatgaatgg atggtggaga agaatggtac gctgtcgaaa aaatccagac 3282 0 tgggcgaagc gtgcagctat gtactgaatc agtgggatgc cctctgttat tacagtgatg 3288 0 acggtctggc ggaggcggat aataatgctg cggaaagagc gcttcgtgca gtctgtctcg 3294 0 gaaagaaaaa ctttatgttc tttggcagcg atcacggcgg cgagcgtgga gcactgttgt 3300 0 acgggctgat cggcacctgc cgtctgaacg gtatcgatcc ggaagcgtat ctgcgccata 3306 0 tcctgagcgt actgccagaa tggccttcca accgagttga tgaactcctg ccatggaacg 3312 0 tagtactcac caataaataa gcgtcaatac ggtgctccgt tgacgcttac tctttctccg 3318 0 ctgacgtaag cccacagcca gccggagcag gatttaccgc ctttccgggt atcaaggagc 3324 0 ctcagggacg tttcatctgc atgaataaca tcccgtgtca gaagctcgtg gcgtaacaat 3330 0 tttgccagcg gggccagtgc agcgccagca acaccgacca tatccgccat tgtactgacg 3336 0 gggagctcca cccccattcg ggagaaaatg tgctgctggc gatacagggg cagatggtcg 3342 0 gtatatttgc tgatgacaac ctgtgcgatg accgatggct caacagcact tttcggaagg 3348 0 atatgtgccg gcatttttcc gctgaacact ttctcacagc agggacagct gtactgcggg 3354 0 cggatatagc ggttgaccac gacctgtgcc ggaatatatt ccagcttctc gctgacttca 3360 0 tcgcgaatga agtgcagggg ggcatcacag tcaggacaac gttcctcagc tggcgggata 3366 0 accttttcag cacggggaag aggtgaaggc aagggcttac gaacaggacg tgttgttgtt 3372 0 ttttcttcgt ccccggtctg aggaagcagt ttgtccagat gcgccgagat ttctgcgata 3378 0 tccgcgtcaa catcctcttc gaacagggaa cgctgcatcc cggccagcga ttcgcatttt 3384 0 ttaccgaaac gctgctggcg tgcgagcttc atctgctctt ccaggatgcg gatacggttc 3390 0 tgaagttctg cattctcagc catgactttt tgcaccatgg caattgccag agcgcgaagc 3396 0 tgttcagggt cactggtggt actgggaagc gagatatcca tgcggtggat tatatgacat 3402 0 cacgcatgga tattcattat atttcattga gttattgcgt tgctctgagc atcttcgggt 3408 0 tcttactggt atacccattt tgccaggtca tgccctttca cctgttgcca gtcaacccca 3414 0 aagaccagcc agtgaaactc atcctgtgtg agatgccatg tggcatcacc tttccggggc 3420 0 cagcggaagc ttccccggtg cagtcgtcgg gtacacagcc atacgccatg tttgtcccac 3426 0 cggagaactt ttatgcggga gcggacttta ttggtgaaga caaaagcagc accgtcatgc 3432 0 catgcagcgt taagttcgtt ctggacgtac tgtgtcagtg tgtcgatacc ccggcgcata 3438 0 tcgacgggtt ttacgaccag gaatacgtta tcaggcgtca gcatggcgaa gagcccggaa 3444 0 aacatcggtt aactgagaag gctggcagca catccggata ccaccgggca ggaagagagt 3450 0 gacaggctca tccgacaatg gtctgccatc agtcattccg gaagagccag atactgaaac 3456 0 aggaataatt tctggtgctc tggctcgttt ttcggctttt gcgacatcct gcggccactg 3462 0 gcgcagggat ttaaacggaa tgtcgtaaag ttcacagtac tgttcacggg taaggccgct 3468 0 ggcgcgccat gcggcaacgt gatgtttttt ctgatcaagc gtccatcggg gttttgacat 3474 0 tgattatctc cggtaagttg gtgaatggat gtcggtaatg ctaactgact gaagatccct 3480 0 gtgaagatga cttccccgta acgacaccag gatgccaatc aatgagcgga agcatgccaa 3486 0 atcgtgatcg attgtgatgc caaacagtga tcggaaatgg atgccaaacc atgatcgatt 3492 0 cagatgccat tttgcatcac gccaatacag aggtgaaata tgacaaaacc ggagttttca 3498 0 ccccggtctg agatttagcg tcaggacttt ttagcgctgt attcttttat cagttcatca 3504 0 acggagtgca gagccagctt ctctaccgct tcacttcggg tcgagtcact cagcgcagcc 3510 0 agacggtcaa tttttcttag aatccgcatg cgtagcgata atgacacggc tgttttttta 3516 0 tccttatcga gtacgacctt ccctgtggac tcaccggttt tcagttcagc attctgtgcg 3522 0 agcgcttcat tcatccggcg gagggtcttt ttatccaact ggcccggatt aacgagatga 3528 0 taggaatgac ctgccttgct gtatttgatc tccgcagaat atgactcgcg tagctctttg 3534 0 agggcccggg ttaatgtcgg ctcagagcat tccagactgg ttataatgtc ggcagcggaa 3540 0 acgggcttgc cggtgcccag taagttggca agcttaaaaa tccgggcctg tctggtattt 3546 0 aattgcatcg taagatttag cctgcttaaa gggttagtgg ttcaataggc tgaaaaatga 3552 0 aggtactgct catctttcga ataaccggtt gatcgcctaa cgcttcaacc ggatcaatgt 3558 0 gttttatgcc tgcaaaattt actgacgaca tctggctgcg agtgcatttg caggacagga 3564 0 tatactcatc ctccagatag ccggtccgct tactgacccg ttgcgtaaag cctgacacaa 3570 0 tcacgttgtc gaaaggtagc gtatgtaaaa cgataccgac caggcggaac aagcagccat 3576 0 ggacgtggtg ggcatagttt tcgcgtacgg ctttttgcgt catggctttt tccgtcagct 3582 0 ccgttccccg ggcattaacg ccgtaaatct tatcagggaa atcttcaatc tcagctaaat 3588 0 caacgtccag caggactgct gatagctccg gctttacttc aaatgcaaca agcgtttcac 3594 0 gcggccattc agtttctgcc agcacacccg ccaggtatga ttcgaaaaac gcggcgtctg 3600 0 tccggaactg ctgccgggca tctgcctgag ccgtggcgag ccgtttttca tgttcttcag 3606 0 cttcaaactt ccagtttgca tactgttcgg cccaggccgt ccgttgttgc tggtaccggt 3612 0 gctgtcgaag ggtattctca cgctccacat caatcagctc ctgctgccac cggcgaagat 3618 0 tttcggcgtg gcgctcagct ttagctgatt ccgattcaaa ccatttaccc aaaaaactaa 3624 0 tgccttcgct ctcggcaggc ttttccggca atacaaggta gtctggcttt tctggacgca 3630 0 ccggtgccgg aacctgaaaa ggcgacgttc tgttatgcag gtatactgct tccagctctg 3636 0 cccagctgat gcctgttttt ggatccggcg tcagctcgtg aatattacgg attgcggtta 3642 0 ccgctgacat gagttcagcg gctttctgct caagcgcctg tctgagcccc gggtcggttg 3648 0 ccgtccggtt ttcacctctg gaacgcgcgg cccggtcaag ccgggtacgg taactcagcc 3654 0 cggtaccggg caagcccaga ttggcatagg tcccccggct accaaaagaa acggaagcac 3660 0 ctctcggccc gacactcagg ctcggtgcac cgttactcag gttgaggcga acgccaggaa 3666 0 taatgttgat cgactttctg aacctgaacc ccattatgat ttccttaatg atgctgggtc 3672 0 acggtaagta atctgattcc atcagcgctt tgctcgttct gtaacccata aaaacgagcc 3678 0 ctgtccagaa tgccagccgc ccagcggcga tgtgtggcgg gttcacacat tgctccctgc 3684 0 gacttaaaca cggcctgggt agagttcagg atccgcagag cgtcagaatg ctcaccctga 3690 0 gtgaccatca gcgcgttttg aatgacctct atctgacccg ggtgaatggc cgttttccca 3696 0 acaagcccgt gtgccatatc aagagccagc tctctggcca taacggcatg atcgtcaata 3702 0 tgctcacata caggcgcggt cagggcaaaa tcacgcgggc cgaagaccga aacgagcatt 3708 0 ttgatgacgt agcccatcgg gctgtcatac agcgtcaggt cccggggacg gcgaagcgac 3714 0 acaacgttca taagatcgtt gccgccgatt cgaagcgcaa taatgcggtc gtggcaggga 3720 0 tgttcctcca gacgggtagc cagctcgcgc atctgaacca cgtcaaagac atcttctgtt 3726 0 tccagcgttg gcatcatgca caggtgagtc ccgaccatga tatcccacca ttcagctaac 3732 0 gaactgaggg taaatttagg cagcacaaac ccgtcgacag cggaaagatc ataatgcgct 3738 0 tttaaccatc tgcccatttc ggcatgccgg gggcgaatga acaccagagg ccagtcattt 3744 0 ttacccaggc tactcatgct gttactgagc tcgtgcagca ggtgctccag atttttgagg 3750 0 gcgacgggga tgtctgcttc actgacagca tcctccaggc aaatcaccag agagcgcaag 3756 0 cccgggattt tcccgtgcag gacggcatca gcaatatctt cccgtgttgc aggcatgtat 3762 0 agcgtggctc ccagattcca gggagaaaga cgatttttca tcagagtacc ttcttgataa 3768 0 tggttacagc ccgatactgg ccgagggttc cccccatttc tgtaacaact attccctttt 3774 0 cacgagcaag ccctacaagc aaggcaacgt ccgggtcgtc aatagaacgc acaaatacat 3780 0 ggtccggtac ccgacgtaat acagcccggg ttgcttcagc aataccgggt ttaatacgat 3786 0 tgacgctgtc cactttaaat tcatcggcca ggaacgcgat aacgtcgcga cttgtctgcc 3792 0 ataagacccg ggctgattcc gtattccagc tcaggggagc gagggatgac ggtgttaact 3798 0 tcttacggaa atgagcgacg gtatcggcaa gcatccggct gcattcgaat tcactgagat 3804 0 gctcgcaaac catgcacccg tgtaatcctt cagaggacca tactgaccgg gagatcaggc 3810 0 ctgataccgg cgcccccatg atgccaaaag gaatgagcca gtcatcatca ctggctgcaa 3816 0 gccaggagca gccacaggga tcggccagga caaccagtcg cggctgctca ggatagcccg 3822 0 ggcgatcttt cagtgcgcgt acaagctctc cggtaattgc gcctttacct gtccatccgt 3828 0 caacaaagac aataccgctg gtaccatgcc gctcttcaat gacgtcgagg gctgcaccgt 3834 0 caattccacg atcccggata atgctgatac cgtaatgcca tgaggttttc cccatgtcac 3840 0 gcagggcctg gtgcagcata acgcccgagc ggaacgccag ccctgacaag actggccagt 3846 0 acaatgggct catcaccgaa gcgttcggcc agagcaatag cgagctgtgt gacttctttt 3852 0 gcaagcctct ctgcgccccg atccagcgcc cggtgaaaca aatcaagatg ccattgtgta 3858 0 ggcgctggct cctggctgag catgtccgaa taatgtttct tcccggactg aatcagttct 3864 0 tcttttttct caaccggcgt catctcaatg acaaccggct ttagcagaaa ttccacgtca 3870 0 ccgggctggt atgagccggt aaatgtttca tgtggctgca ttttaatttt ctccaaaaat 3876 0 tcgctgtgaa atggcatctg caaactgact ctgacgcggg atgccaaacc agctgcacag 3882 0 tttcataaaa cgatgatcgc tcaggctgtc gcccaaacca attacgggga aaactcctcg 3888 0 ttcagcccga agtttttcaa gcagccagct gactgccagc cctttctcaa ccggggtggg 3894 0 aagccaggcc acgttattac tgttgcggtg gatgtagaag ccctcggtcg gaaacaccgt 3900 0 ttctatctca tctgcaatgg cattgagctc gtcaaggcgg gtgctgtcgc ggtgtttcat 3906 0 caccatataa accgccattt caccgtattc gaagttcagc cttgcccagg cattgattcc 3912 0 ttttgcgtcc atcatttcag tgatcagacg ctgcatcgat gtcagctttt cctggtaggg 3918 0 agccagctgg ccgagcatat gggccttcca ctcctcgtcg ggtttgcctt caggcgtgag 3924 0 aatgacggcc ccgtgcgttg tgattgccca ggagtggaaa gggatccgta cgcggctgat 3930 0 ttcttcagtt ccccgtgcgg taacgggtat gagttcagcc tgctccagga gccagtccac 3936 0 caacatggac tgttcttccg tcataaagct tcgtggattc agggtgcgat caacggcacc 3942 0 ggtacggaat ggctccaggg ccagctcgtc caccatttta cgacgggtct gaaagagcgt 3948 0 gtcgtcaagg tcgctcagaa caacgggttt attcataggt aacaatctcc acgacgggcg 3954 0 caacctcagc cagcgcttta agaagctgcg tgtcaatact ttctgcgggt gtctcagtac 3960 0 acacaagaat gcggtcaaac tgctggtggg cgacgttata gacaaaattg gggatgccca 3966 0 gcccgtagtt atccgtaaag gaaatggcgg actcaatggc ataaccaacg gcgacagggg 3972 0 agcgggtggt cgatccataa aatgcctgtg ctccggcagc ttcgagccgt tcagcaagca 3978 0 ggaacggctc ccagacgaat tccccggtcc cgagaaccag aatacgttcc cccttgtgga 3984 0 cggagacctc atggccgaga tcggccgcag gtgcgagcat ccccagtcgg ccccatgact 3990 0 gtttcccctg gatgtcccat tctcctcgtg aagttacgtt gactttcggc atgtccggga 3996 0 caggtgcatc aggtaatggg gtccatcccc actgaccgct tacaagcgaa accgaagtga 4002 0 cgggcaaggg ggtgcgctcc gacagggcat tgccactcca gtcggtcagc gttacggcga 4008 0 taacctgttc aatatgttga agcttgccgg tattacgcag ggcagaaagc aggttaataa 4014 0 aggtattacc ggtggttgcc tcgtcatcaa tcaaaaccag cgttcgtgcg ttggtaacac 4020 0 gacgtctttt ctcttcatca tctggcagat agatcagatg atcggtggcg tggctgtgtt 4026 0 cttccttgaa ctcgcaaagc aacgtgccat caaccgggtg acgggtagag gtcagataga 4032 0 cagattcacg atgctggtgg cgcacttcat caaatacacc ggccccaagc ccaacggcgg 4038 0 tttcagccat accgataaac agtacgggtc ctgtcagtgt cgaggggaac tggctggcaa 4044 0 gctgtctgta ggcctgccgc atgactgagg gtggcacggg aatgtgcctg ccgagtactt 4050 0 tgctgacaaa cagaaaggcg cgtttcgggt tacgtctttc agcgatgtca aacaggtcat 4056 0 cgagcgaaac ttcaccctgg tcacgggtta cctgaatcgt accgcatgag agggtacggc 4062 0 gataaatcat atcttcgagg atatcagaca taaatacgcc ttaattcaga aggttagaga 4068 0 gtgattccgg gtatgcaatt acatccgtaa tggatctcac cgcaaccgga gaaaaggtgt 4074 0 ttttagcgct ctggcgtacc atatcttcag acatcagacc gagcttaaag gcagcaaata 4080 0 acccaggaag gttcacaccg ctgtgaaggg tataacccac cccccctgac ggacgcatgt 4086 0 tggtttcaag cagcaccggg ttgccattca catcgtttcg cgtctgaaca ttcaccagcc 4092 0 cgtcggcctt cataacacgg gcgcagtcac acgccagttc ccaggcgctt ccttcgttta 4098 0 ccagatactg gatagcccct tccttacggc gtcccacggc tgcgagtatt tcgcccttat 4104 0 ccgcgaggat atcgacggaa aattccgggc ctggcaggta cggcatcaaa acaaggggtt 4110 0 taaacgactc agcagctgat gctgctgcaa tatactgttg cggactgacc agacgatgtt 4116 0 cgggatgatt aaagacggcc ataggcgaag cactgtcatc aaagcgccag aatcccatgc 4122 0 catagatacc cgtcaccggc ttcacgcata ccgggctgtc agtgaacggc ggggccgcga 4128 0 ggtgtgtctt taattctgcc agcgtattca cccgccagga tggtacgacc gggagaccct 4134 0 tttgctccat aaactgagca aaagtaactt tttcgtcagc cagagttaac cagtcgacgc 4140 0 ccgttgcacc ggtagtaagg gtggcaccgg tcggttcaat ggctgaacgg tgttcttcaa 4146 0 accactggct gttacggcca gtatgaatat ggtggatgcc gtaggtctga atggtttcct 4152 0 ggataaactg aagacgtttt tgaggatctt caggttcagt caaagaataa tcggcaacgg 4158 0 aaaggatttc atttctttcg ttacggtggg aggcaaaaac ggtaatggca aaattatttt 4164 0 tttgtgcaaa tgattttacc ccctgaataa tatctcgctg ggaggataaa ccttccataa 4170 0 accaaatttt cttgttcatt ttttttaatt atccggaacg ccatgcaaat ttatgattga 4176 0 gaagtgagtc tatgagtgtc taagctacat gtcaatcata atatgattaa taactcctgt 4182 0 ggttatggag tgcgtcagtg ttttttggat tccttataac acattgatat ttaaattaaa 4188 0 aatagaaaaa ctaacaccct gaaaaggatt tctttttgtg tttttacaga aaaccacaaa 4194 0 aatttccctt gtcagagaac ttcatcatga tatgattttc ttcgtcagtt actaaatata 4200 0 cctttgattg tctcggtcat taccatttta aggaataaaa catggtttca ttagttaaga 4206 0 accagacggt atcactcagc aaagaatcat ctgcattaag ccagcttcat ttcggtctcg 4212 0 gttgggatcc ggttaagaaa aaaggtcttc ttggaggatt gtttggaggc aacgactcaa 4218 0 tcgatctcga tgctggctgt gtattaatgg acagcacagg taaaacaatt gacaccatct 4224 0 ggttccgcaa actgaaatcc acctgcggcg ctgttgtgca cagtggcgat aacctgaccg 4230 0 gtgagggtga cggtgacgat gaagtgatta aggtcaacct ctcccgcctg cctgcaaacg 4236 0 ttgaatacct ggcgtttacg gtaaacagct tccgtggtca gtcgttcaat gacgtcgaaa 4242 0 acgctttctg ccgcgttgtc gatcaaaccg gcaaagagct ggctcgctac aagctgactg 4248 0 agcagggctc acataccggg atcgttattt cttcgctgcg ccgtaataac ggcaactggg 4254 0 actttaccgc ccttggccat gcctgtcgcg gccgcacaat tgacgatatg cactccgata 4260 0 tcgtttcagc ggttattcgc taatgaacct gacgccgggg ggcaatgccc ccgttccagc 4266 0 ccaggagttg cgggtccgga tcacctcggg cggccaggtg gatgcttcgg cgtttcgcct 4272 0 gtatgccgac gggaaggtgc agggtgatgc ggacatggtg ttttatggtc agccacgtaa 4278 0 cgatgatggt accgtcagcc tggtcagtga aggccagtac tcaaccttta ctgtcgcgct 4284 0 caaccggctg aaacctgatg tccagaaaat tgcgttcacc gtgacctgtg acggtgggca 4290 0 gacggtgtcc ggtcttcgta atctttccat cgacgtggag caaggggcta ccggcctggt 4296 0 tagcggcagt gtcgaactga gcggccgtca ggaagcagcc ttaattctgg gggaatttta 4302 0 ccgtcgtaat aatgactgga aattccgctt cgttgcgcag gggttcaacg gtggacttaa 4308 0 accgctggca gagcatttcg gcgtaaatat tgccgacgaa ccggctcccg cagccccaac 4314 0 tcctccggtt gtaacccctc cgccagttga gacaaaaatc agcctgagca aggtatcgct 4320 0 gacaaaagag aagcctgcaa tcagcctgac caaacgggat aacttcggtg aaatccggat 4326 0 caacctgaac tggcaccggg gcagtagcaa atcaggcttt gcaggtatgt tcggctccaa 4332 0 aggaatcgac ctggatctgg gggcctttgt tgagcttcag gacgggtata aatcggtcat 4338 0 tcaggcgctc ggtaatgcat tcggtgatta tcgcgatgaa ccgtatgttc agctcaaggg 4344 0 cgatgaccgg acgggtgatg tatcagacgg cgagtggctg catatcaatg gacgtgaatg 4350 0 gaagcatatc cgcgaagtgc tgatttacgc ctttatttat gaaggtgttc ccagctggga 4356 0 caagactgat ggtgtagtca ccattcatgt gccggatcaa ccgcccattg agacccgcct 4362 0 gaccgaaggt gagaaccgtc gcacattgtg cgccattgcc agactcgtaa acgaaaacgg 4368 0 cgcaattaaa gtcgagcgaa ttaaccagta cttcaaaggc caggacgaaa tggaccgggc 4374 0 atttggctgg ggatttcgct ggagcgccgg ttctaaataa cacagcaaca aaggaaacag 4380 0 gtatgagctt tttcgacaaa gttaaaggtg ccattaactc aggccgtgac gaactgaccc 4386 0 gccaggttgg ccgtttcaaa aacaaaaaat tcatgcaggg caccgttgct gtatgtgccc 4392 0 gtattgccgt atcgagtgac ggcgtaagtt cggaagaaaa gcagaaaatg atgggctttc 4398 0 tgcgctcttc agaagagctg aaggtcttcg ataccaatga ggtgattgag ttcttcaata 4404 0 aactggtttc aagcttcgat ttcgatgttg aaattggcaa gggcgaaacc atgaaataca 4410 0 tcctggcgct gaaagatcag cctgaggccg ctcagctggc cttacgtgtt ggtattgccg 4416 0 ttgcgaaaag tgacggtaac ttcgatcagg acgagaaact ggcctcccgc gagatcgcta 4422 0 tcgcgttggg cttcgacccg gctgaatttg gcctctgatc cacatcccta agggtaaaat 4428 0 atggtttcca cacacatcgg cttcccgact gaaacggtca ttgtttttat tgcgctttca 4434 0 gtcggtgcca tctttattga cctgtttatg caccgtgatg acaagccaat ctcgctgaag 4440 0 agtgctgcgc tctggtccgt attctgggtt gtggttgcga tggcatttgc cggtttcctc 4446 0 tatatccacc acggtgctga ggttgccagt ctgtttgtca cgggttatgc gctggagaaa 4452 0 gtgctgtcgg tcgataacct gttcgtcatg atggcaatct tctcctggtt cgccgttccg 4458 0 gatcgttatc gccaccgtgt tctctactgg gggatcattg gtgccatcgt cttcaggggc 4464 0 atctttgtcg ccatcggtac gagcctgctg agtctggggc cgtacgttga agttgtcttc 4470 0 gctattatcg ttgcctggac ggcggtcatg atgcttaaaa gcggtgatga cgatgatgaa 4476 0 attgaggatt actcccagca tctggcttac cgtatggtta aacgcttctt ccctatctgg 4482 0 ccgaagctca gagggcatgc cttcctactt aaccagaagg aagtggatgc tgaactggcg 4488 0 aaaccagaaa acagcgatgt caccattggc cgtggtaaaa aagcggcgct gtatgcgacc 4494 0 ccgctgttcc tgtgtgtggc tgtggttgaa ctctcggacg taatgttcgc gtttgactcg 4500 0 gtaccggcaa tcattgccgt cagtcgtgaa ccgcttatcg tctatagtgc catgatgttt 4506 0 gctatcctgg gtctgcgtac tctgtatttt gtccttgagg cactgaaaca gtacctggtt 4512 0 catctggaga aggccgttat cgtgctgctg ttcttcatcg cggcaaaact cggcctgaat 4518 0 gcgaccgatc acatctggca tcatggttac agcatcgcgg caacaaccag cctgtatgtt 4524 0 gtactgggtg tactggcgct gggcattctc gcaagcgtca tgttcccggg caaacctgaa 4530 0 tctgaggaaa aggggagtta atccccttaa gtgttaacct gaacaattac taatcgaaga 4536 0 ggttatttta tgagtgtttc tctttccaaa ggcgggaacg tctccctgag taaagcagct 4542 0 ccgtcaatga aaaatgtcct ggtgggcctt ggctgggatg cgcgttcaac agacggtcag 4548 0 gactttgacc tggatgcttc agcattcctg ctggcctcaa acggcaaagt gcgcggcgat 4554 0 tcagatttca tcttctataa caacctgacg tcatccgacg gttccgtaac gcacaccggc 4560 0 gataaccgca ccggtgaggg cgatggtgat gatgaatcgc tgaaaattaa actggacgcc 4566 0 gtcccgtctg aagttgacaa gatcatcttc gttgtgacca tccacgatgc tcaggctcgt 4572 0 cgccagagct ttggtcaggt atccggtgcg tttattcgtc tggttaatga cgataaccag 4578 0 actgaagtcg ctcgctacga tctgaccgaa gatgcgtcca ctgagactgc catgctgttc 4584 0 ggcgagctgt atcgccacaa tggtgagtgg aaattccgcg cagtaggcca gggttatgct 4590 0 ggtggtctgg catctgtatg tgctcagtac ggcattaacg cgtcctgatc gaaaagtaac 4596 0 ttttcatatc tggggctgtt aattcagcct cattcaactg tttgcaggag ctaaaaatgg 4602 0 cagtttctct cgtaaaaggc ggcaacgtat ctctgaccaa agaagcacca accatgaatg 4608 0 tcgctatggt tggcctgggc tgggatgccc gtgtaaccga tggtcagggt tttgatctgg 4614 0 acgcttccgt attcgcagta ggtgaagacg gtaaagtact gtcagatgcc catttcattt 4620 0 tcttcaataa taaaaccagc cctgatggcg cagtagagca ccagggcgac aaccgtaccg 4626 0 gtgaaggcga cggcgacgat gagcaggtca aaatcgatct gaccaaagtc tcagcagaca 4632 0 tcaaaaaact ggtatttgcc gttaccatct atgatgcaga agcgcgtaaa caaaacttcg 4638 0 gcatggtgag caacagcttc atgcgcgttt acaacaacga caacgggacg gaaattgccc 4644 0 gtttcgatct gtctgaagac gcctcaaccg aaaccgcaat ggtcttcggt gaactgtatc 4650 0 gccatggtac tgagtggaag tttaaagctg ttggccaggg ttttgccggt ggtctgtcag 4656 0 cgcttgcttc ccagcacggc gtcaatgtct aaaagacgct gagtctgacc ccggcaatgc 4662 0 cggggttttt tttgggtatc gatccgctat caacgggtga atatgggaaa ggggggggca 4668 0 gaaagcagag ctatgttaat tctggcatga accttttatg caggccccgg gtttatctgt 4674 0 ggttgctggt taaagccagt attccgtgtc tgatatcaac agcatgccct tcggatatat 4680 0 gttacttttg cgacttatga aggaacgggc cctggaaaat aagatacccg gtcaatgaaa 4686 0 attcaaattc aacaggtata gaaacttcag cgttatgaaa aatggtgtca taccatattt 4692 0 acgcctcacc gaatatccag cgtccagaac taagcctagg gaacatatat aaacgctgcg 4698 0 cattaataat aatcaaaaat caggagagtt aatatgaatt tacaatccgg acaaaacata 4704 0 ccccttcagc aatctacgat caggctgaat cttcagtacc ctgccaaatc cggctttaaa 4710 0 ggcgaacccg atacctgcct gttcatgctt aatgctcagg gaaaggtcag tggcgattct 4716 0 gactttatct tttataataa tttgtcttct cctgaggggg cagtcaggct cgttaccggt 4722 0 tcgcagcagg ccagcattga gatagcactg gatcgtgttc cggcgaacgt cagtaaaatt 4728 0 gcgatcaccg ttgtcattga tggtgaagat accatcagtt gaggctgtac gcttactgac 4734 0 aaaatggcga ttgagaaggt gcaattgact tatttggatt tggtcgtggc gaggtggtga 4740 0 ccctgcattc tgctaaccgg gttatgagtc aggagtcagc gatagacaaa gggacttatc 4746 0 tgaccgggcc cctggaaaaa tggcgggaga gaatgatacc ttcctgctga cgagacagga 4752 0 ctttgagatg acgagcgata gtgcggcagt gatgtacagc ctgatcggta gctgcaaaac 4758 0 ttaacggaat cgagccggaa acgtggctac gccacgtgat cagtgtaatc aacacctggc 4764 0 ctgccaaccg catgaaagag ttgttgccct ggaacgtcac tctctctgta aactaatttt 4770 0 taccccacgt ccttcacggt gcgcttacac tctggacaag tatgtaaatg ataagttaaa 4776 0 aataatccgt gcatttcctg tgacgatatt agttgttggt aacgaaatct cattagcgga 4782 0 tcggaaatgc acttaaccta atacgttgcc actgttccgc caggagttgc agtggcaacg 4788 0 tattctaccg tcagtgatag cgttttgtta ttatcagaac tgatagttca gcgacatcca 4794 0 gtaatttcgc tcaggtatca catatcctgt tgttgatgat cccgtctgga agtaatcacc 4800 0 ggcatacagc gtactcttac cggcactgta caggctcacg tcactgtaat ccttgttgag 4806 0 caggttattc accgcagcat tcagcgtcag ggcatccgtc atcttccacg acagacctgc 4812 0 atccaccacc gtccaggctt tcaggtattc tcctttctca tcatacactt tcttctgtac 4818 0 agcgctcagt gacgaataat tctgggtgaa acgtggtgtt ttcccgcgat aacgggcacc 4824 0 cagccatgat gccacctctt cggtgatctg ccagttcagt ttcgcattca ccatgtgttc 4830 0 aggggtataa ctcagcggcg cacctttgtt atcaccatca cgttgttcac ttcgggtcca 4836 0 ggtgtaattc agtgacagcg tgacatcctc tgaccacagc ggcaatgtgc cggcaaattc 4842 0 cacaccgtgc aaccgggcct ttccgctgtt tacatagcta ttggtgttat catttatgga 4848 0 ataagagaca atcttgttgg agaagtcagt cataaaacct gtgacattgg catttagacc 4854 0 ggcggggtta tcgtaataca ccccagcctc ataactgacg ctctcttccg gcttcaggtc 4860 0 ggggttacca agtagatttg tttttccctg cccggacaca ccactaatcc ctttatgtag 4866 0 ctgccccatt ctgggtgcct tatatcccgt ggtcacaccg cctttcagcg tccaggcatc 4872 0 tgccacatcc cagaccagat atgcacgcgg actgaagtgt cccccgaatt gctcatgatg 4878 0 ttcatagcgg ctgcccgcag tcagcgcaag tgcatccgtg agatgccact catcctcagc 4884 0 aaataccgac cagcttttct gccggaaagt ttcacctgtg ctggcaagga caactccgtc 4890 0 tttcatggac gagctctgaa actcgccccc caccgtaacc agatgagatt ctcccagagg 4896 0 ggtaagcagt aatgaattca ggataaggtt cgattcctta agctcccgcg gctgaccggc 4902 0 aagcccccat ttgtcgcgct tcagtacact gcgtacaagc tcacgacctt tattttctgt 4908 0 ctcgttccag ttcagatacg atttccatgt tccgaaggtg aaagtatgat catagccagc 4914 0 tgaaattttg tttcgctcat agcgcagggt ccggtcatat ccccccgtca gactccccag 4920 0 ttgcccatcc cggttatcat aacgctgccg ggtggtatcc atatcaaacc agagcacatc 4926 0 ctgctccgac gccttccagt caagacgtgc accaagatta taattctgtg actccgtggg 4932 0 ataaggaata cgcgtggctg ctgtatcgct cagtgatgtg accgatgaac cctgacgctg 4938 0 ttgtgtgcta ccgcgtacct gcaggctgac agaatcatcc acaaggggac cactgctcca 4944 0 gaaattaaac tggctgctgt taccccattt gttgctttcc tgcagattca gccctgcatt 4950 0 gacggaagag agccatttgt ctgcattctt tctggtaatg atattcacca caccgcccat 4956 0 cgcatcagag ccatacagtg tggacatcgg ccccctgata acctcaatac gctcaatggc 4962 0 ggccagaggg ggcatgaacc cggtattcat ggcagaaaaa ccgttgggag tcacgtcact 4968 0 gcttccgccc tgacgaacac catcaatcag tatcagcgtg taactggctg gcattcctcg 4974 0 gatgctgatt tccagccctc cggttttacc cgtaccactt tcaacatcca caccctctac 4980 0 tgatctcaga gcctccgcca gatcgtggta ctggctggac tgcaattcct cctggctaat 4986 0 cacagaaaca ctggcggctg cgttagtcag ctttttctca tagccggatg ccgagacaat 4992 0 catcacatcc tctgcagcag ctatgctgct ggctgaaaat ccgagacagg gaatgactac 4998 0 ggaagccaga gtggttattc gcatattact aatctccgat catgttaacc ggcaagacaa 5004 0 tacacaaata caaacaataa tgagaataat ttatatttgc cttttacaaa aaataaagat 5010 0 tattgacaaa accaaatata aataacgact gcctcggcat gccagttaac agctatccgt 5016 0 atggcgtgtt cggttttgcg aataaaaaat ggttactgta gaagcggatt tccaccacat 5022 0 gtcaaccatg aatggtcagt gatgcgagac gactgggatg atttggtcga tgacttcttc 5028 0 cggcgaatac tgatagaaac attgaaatat tgtaagagaa agcgttcaaa attctgtggc 5034 0 acgtgaaaaa ttctacagcg tcatcacctt attcagtcga ccttcaaaat aaacgtttaa 5040 0 cagagacaat caccatttgg attgtccgct gaggaggcga acaatttcct agacagcttt 5046 0 atcatgtcag cccacattgt tggcgctggc aatactaagg acaaacgatg gggaagtagc 5052 0 tttttagcgt tattttcggg agtaaaaaac gtggtatctt tccgtatgtc agttgtatct 5058 0 tgctggtatt cgtagtcgtg ataaggcata caacgatatt tatcttgacg ttagtgaaga 5064 0 ataagttgtt ttgtgatcta tgttaatctg ggattacaat ccgggcttga tacatcgcat 5070 0 cacgactttt attctcttca gaatagaata tgttactccc cgctttacag gctcaggatt 5076 0 tgaattacaa attatacttt taagtgaaca ataaccaagg gtatttctta tttcctgaaa 5082 0 ccaggcttgg cccatttcgg gatgagtttg aaaaaactct tgacgcatac gatagtgatg 5088 0 aaataaacga aacaaattac gtcaacaaac tcaggcgtct tgcctgacat gctcctgaca 5094 0 tcattgatat tcacgctcat ctggcatatg catttgcgct ctttatgctg caattctggc 5100 0 gaatgttcat ttacagcgtc atcaggatgc cgttatactc attgataaaa tactaacata 5106 0 taaccctgag aataatcagg gaacacgctg gttactgggg gcggaattgt tacgtgctgg 5112 0 caagcatggc agggctctgt acgtattgac aggacatgtc aatgaatttc ccccctactg 5118 0 gtacgagctt gctcttttac attttatgaa tgaggcatat attaatgctg caacggcatt 5124 0 tcgatatgga tttttaacaa gtatatattg ttgaaatgct ttgttagaat ctttatccat 5130 0 tccctagggc tgtatagtat gatttttcag gtatttctga atactgccaa atattattgc 5136 0 aaaatattct ctaaattatg aattaaatat ccataagcat tattgcctgg gaactggaca 5142 0 tataattact cttctgtgct aaaggaacgt tctgaaatgt ttaagtatgc agagatgttg 5148 0 atggcggaag aagatgataa agtatgtgaa cttattttta aacaacaaga taatttgatt 5154 0 ttaaaaataa atgttagatt tcccagaata attataaaga aataccgaac attacaaggt 5160 0 aaagtcgtat ggctatggat attgccattt gttattgaat ggttaattgt gtgtactttg 5166 0 ggtgtaaaca gttagcttgg taaaagtaaa tatcctgatt gttgtttgtt aaggagtgag 5172 0 atgcctgtgc gtctggtgtc tattatattc ccaatattat tggcgctatt cttgctggcg 5178 0 taggcatcgc catactatga atattgtgtt tgtcgtgatt caatttttat ttataacctc 5184 0 tacccggagc aaattcaggt aggtcatgca taaaaatatc tttctatact acgaaaatta 5190 0 tttttgtgaa agtattgaca acgctaacta tttttaatta tatattcatg atgctctagg 5196 0 catcacattt tctccatggg gtattccctc cgccggcact atgtgttgct ggcgtttttt 5202 0 tatcaattct tactttttaa tcccactgtc ctttccacca gaaacatacc tcgtttctac 5208 0 tgtattttga gaatatagtt cccagaatac caattatata taatacgttg taatatatgt 5214 0 attccaatta aagccgttat tataataatt atcatatatg gttattttca tattgatttc 5220 0 gtcagaaata gaaaatgctg atgatgaatt gtgaataatc aaactgacct ctaattatcc 5226 0 tgtatggagt agtgcttatt ttcgactcaa tttctactga ttagattatg gttatcagta 5232 0 cagtgggtta tgaaaaacgg actggatctg ccagcagtgc ttctattatt attcaaaaag 5238 0 aacttcagcc ggacaatgct ataatccagg gaaaggctat aagctctgtt ggacggaatg 5244 0 tggaaatcag cactggtaaa aggggaactg acattaacac aagaaggatt cctgcaagca 5250 0 actgcttatc tgcccggaac gcagaattaa agcataacca cacaggagcc agaatactgt 5256 0 ggtcgtacgc attcagtatt gtgacaacta atagaaataa aaatctggcc ggtgcgaata 5262 0 ttaaacgatg cgataccgta tagtgtaagt caaaagtaac ggggtattta aaccatcttt 5268 0 ttatatttat ttaacataat gcagattctg atgtattagt tcagttgttc gccagaatca 5274 0 gcgctcgatc actatgcgtt ttagcagtgt gctgaagaag ttcttcatca ctgcgttatt 5280 0 cagaccgttt cctttgtgcg gcatattttg tgctactcca tggggcttta actttgccta 5286 0 tagcctgcaa ttcgatattg ccaaccctga tccatatgca gcgacggggc atcctctggc 5292 0 cgggcactgt gaatgcatcg tatagcatcg tattaacgat gctccatcac cgacctttct 5298 0 gacaagctgt aggagataat ttcccggtta aacagatcgg agaactggcg acaggtacca 5304 0 cttttcccct gtaccgagaa ctctgtaaca tccgctccca tttttcgttg gcctttgtca 5310 0 aagttccggc tcaggatatt gggcgcagat cacttatttg gtggacacca ctttgtcgga 5316 0 tgcttcagat tatgaccaga tggatttcgc tggacgctta cgattacatg caccatattg 5322 0 tcaacgatta cgccactgag tgtatgacac acattaaagc gttaggctca ggccttatta 5328 0 caatgtcatg ctagtgtgct tgtacgccgt aaatatctgc atgataccag aatgaccggc 5334 0 aaactcgtca gtggatataa agaaaatcaa gtgcgctgat aacgatgcca catctgtggt 5340 0 tggtggcaat atgcagattg ttgttatttg tcttcattgc attctaagaa gtgtttctta 5346 0 tcagacctga tttttttgcc attattttta atgaggtctt caagtggaaa ataggttagg 5352 0 cgttcatgtg gcagcgcggc acgtccccat ttagtggcaa actcccgttg gcgtgcctgt 5358 0 aacagttgct ccagcctttt tattttgttc tcattcatcc ggttttcctc gtatgctgca 5364 0 tcacaccact gtgctaatga aaaatgtaat cagtgtggtg gacgtgtttt atccgcattg 5370 0 gaattgtcgt caactaaagg agatgaggcc cgtttgtatc gcaatgggtc tatggcgctc 5376 0 atgcccgttt gctgttcgat aatggcttct ctgagcatac ggtgttgcag ttctcgtaaa 5382 0 aactttgcgt cttctggtga taaatccatt gttattactc gtaaagcaat gcgctgtagt 5388 0 gccttacgct accgcgctga tggttcttat ccgttttatt gaatcggaga acaaactgtg 5394 0 agctatcagc ctggtggtct ggttttgcct gatttaagcc gccgtgggta tttgtccaag 5400 0 aatgcttcaa gctccaatcg ttttggcctg gtgaatggag atgggttaag caaagactct 5406 0 cgttgctggt gtactttttc gcgctggcgc tcaagcatgg ataatgcgat tgcctgtagt 5412 0 tcttcgttag tcattgtctg cacctgggaa gcaatttacc ggagtacctc acactacggc 5418 0 aaaaatgttt tattgttgca acttgcgtaa ttattcaggt cagtttggaa cgcactgtat 5424 0 aaacataaat aacctgatac tgttgtgtgt tttcaaagaa aacacaggta tttttcacat 5430 0 aaaccttccc cttttcatat ccgaccactt aatcaaaaaa cggttttata cttgttgccc 5436 0 ccactggggt catcttgggt gacttttaac gtcaggtgac gcattgtcac ttcagacctg 5442 0 ctacctatac gccggaatat aatggtcaga gaggcatatt tcgacgcccc taatctgggg 5448 0 cgtttgattc aggatgtctg gaacaatccg ggctttgtgt caccgggcgc atcaaagctg 5454 0 taccacccgg gatgtggcgc tggatcgtca tttaccggac tgcgaagaca tacttaaaga 5460 0 ggtgatatgg gcgttcagtg attttgtccg cgataatcgt ggtgtgtatg atccggaagc 5466 0 ccgttacccc gccggtaatc cctggtatcc cgtaacaggc cagttctgaa agcacagctc 5472 0 agtagatttc ccgcattcgc acaatcttca taaatctcac aggacattct gaccatgttg 5478 0 actacaacaa gccacgacag cgtatttctg cgtgccgata attccctgat cgacatgaac 5484 0 tatatcacca gtttcaccgg tatgaccgac aaatggtttt acaagttgat cagtgaaggc 5490 0 catttcccta aacccatcaa actggggcgc agcagccgct ggtacaaaag tgaagtggag 5496 0 cagtggaagt gaagtagagc agtggatgta gcaacgaatc gaggaatcct ggggggcagc 5502 0 agcatgaaac gtgttgtaat gccggtacgc tggcaatgtg caaaatgcca gcgctggtat 5508 0 tgtggaaccc ggccctgccc ttggtgctgg cgatattccc gttcatcttc ctgctgatac 5514 0 cttccgttca gcagcgggtt gttatccctt cctgactgat tcgtcattcc attcttattg 5520 0 attagaactg gcattacacc ggtgccggcg tgctttcctg cgtgtctgcg ccggttcagt 5526 0 aaattagaaa agaaacattt gtcagcgcca gtgatataag gcgtaacggc taacaatctt 5532 0 ggcgttaata cattccgagc aaataaccga agcgttactt ttagtgacgg ggttatccaa 5538 0 tacttttcta gtcagtgttt agtatttatg caagcgatat aagtagtcac cgcttagact 5544 0 attgacattc atgatgcctg ttaattcaaa tttcaggtat gatcagtcat ttattgttgt 5550 0 gatactgatt ccgctagttt agcataactg tcctgcaaat cattgttcaa aaaagaaagc 5556 0 tcctacaaac tgtatcctga atctctacca gaagataata tacttggtta tttttgtgca 5562 0 taagctcaca taaaaataat attaattatg ttttcttaga gatagaaaaa taaacaggta 5568 0 agcagaagac ggactttttt aatgcgaaaa cgtattcttt ttattggccc accgctgtac 5574 0 ggtttgttat acccattgat ttctctggct caggcctttc gtgtaattgg acatgatgta 5580 0 gtaattagta gcgctggcaa attcgcgaat aaagcagcag aagctggact ggttgttttt 5586 0 gatgcagttc caggtttaga ttcagaggct ggatatcgcc atcaggaaga gttgaggaaa 5592 0 aaaagtaata ttattggtca tttctctttt tttagcgatg aaatggcaga taacctcatc 5598 0 gattttgcag gaaaatggag gccagattta atagtctatc cccctcttga tccggcaggc 5604 0 ccattggttg ctgctaaata tagaattcct tcagtgatgc tggctgttgg attcgcgcat 5610 0 acatctgccc atattcagat gttaaaccgt tctttaagca atgcttacag gcggcatgga 5616 0 gtcagcggtc cactatgtga tttagcatgg attgatgttg ctcccccaag tatgagcatt 5622 0 cttaaaaatg ctggagaacc ggttatctca atgagatata ttccttataa cggaggtgct 5628 0 gtaaaggaaa catggtggga cagggattct gatcggaaac gtttacttat cagccttggc 5634 0 actgtaaaac caatggttga tggtctggag ctgatttcat gggttatgga ttctgcaaat 5640 0 gaagttgatg ctgatatcat tttgcaactt gcaataaatg ctcgtactgg tttacgaaaa 5646 0 ctaccatcaa atgtacgtct ggttgactgg atacctatgg gtgtattcct taatggagct 5652 0 gatggattta ttcatcacgg tggcgcaggt aataccctga cagcgctgta tagtggaata 5658 0 ccacagattg tgtttggcga aggtgcagat cgctctgtta atgcagaaat tgttgcgaag 5664 0 cgtgggtgtg ggattattcc ggacaagcat ggactgacca gtgatttggt aaatcgcctt 5670 0 ctttatgatg attcactacg cttctgttca gatcaggtag ccgctgaaat ggctgaacaa 5676 0 cccagtcctg cagagattgc agaggttttg atgagaaaat taaaaaacaa cgggaaacaa 5682 0 ttgtagcgta ttgctgaaat tttcaacgag aaatgttatg agtaatataa tgtccttcat 5688 0 cacataaatg aaggacatca ctaaataaat gagatagtct cccataataa tattgcagaa 5694 0 agagttatct gacgataaaa cgatatttta cacagagtta ttatttgata ccttcctgca 5700 0 attataattt gctaattcat caataattgc tccgcgccac caggcataat cgtgaccacc 5706 0 ggtatagaca gtgaggttac tttccaaacc agctgcgatt aacgaatgat gcaatcgctg 5712 0 aacatgtgag acggttgtac cttctaaaga accgactcca agtcgaatat ttacatcttt 5718 0 cggaggcgct gaaagtatct gctcacttac ccaggaggta ttattctcag gtaatgactc 5724 0 caacttactg atagtgtttt atgttcagat aatgcccgat gaccttgtca tgcagctcca 5730 0 ccgattttga gaacgacagt gacttccgtc ccagccttgc cagatgttgt ctcagattca 5736 0 gattatgtcg ctcaatgcgc tgagtgtaac gcttgctgat aacgtgcagc tttcccttca 5742 0 ggcgtgattc atacagcggc cagccatccg tcatccatac cacgacctca aaggccgaca 5748 0 gcaggctcag aagacgctcc agtgtggcca gagtgcgttc accgaagacg tgcgccacaa 5754 0 ccgtcctccg tatcctgtca tacgcgtaaa acagccagcg ctgacgtgat ttagcaccga 5760 0 cgtagcccca ctgttcgtcc atttcagcgc agacaatcac atcactgccc ggttgtatgc 5766 0 gcgaggttac cgactgcggc ctgagttttt taagtgacgt aaaaccgtgt tgaggccaac 5772 0 gcccataatg cgtgcactgg cgcgacatcc gacgccattc atggccatat caatgatttt 5778 0 ctggtgctta ccgggctgag aggcggtgta agtgaactgt agttgccatg ttttacggca 5784 0 aggagagcag agatagcgct gatgtccggc agtgcttttg ccgttacgca ccacgccttc 5790 0 agtagcggag caggaaggac atctgatgga aatggaagcc acgcaagcac cttaaaatca 5796 0 ccatcataca ctaaatcagt aagttggcag cattaccaga aaatgataag gtaaacattg 5802 0 aaaagcagcc gactgatgac tgttttttat agttgcattt ttattttttg ttattttcat 5808 0 ttatattccc ttacttgtcg tttaaaattc ttctatataa caggaagagg taaccataga 5814 0 atgaacgttt attttcctgt atcagaacag ccataacttt tattttatag ttgttatcag 5820 0 tgaatgaatg caacctaata gaacaatgag gaaaacaatg gagaaaaagc gacggaccgg 5826 0 acgccatagt tcatattctc gtgtatcagc ctcacgtatc aacctttctg aaatggtttc 5832 0 ggtttctttt cctcgcacca gaatatgtct gtaatatttc ctcatgacat ataccgaaaa 5838 0 ctgaaaccag attaatatgg atggacacac aacacataaa cttctgatga tatcacccgg 5844 0 gaaagtatct tgggcgggta aaagaaagtc atatactctg gataaaatca tcatcgagat 5850 0 aaatgagacg ccagcaccta tccagtattc gatatgagaa gatgctgcat tatatgcgtc 5856 0 agtaaaattt ttctttctta atgaaggtgg aagtgctgaa agttcaggaa tacgttttct 5862 0 tgtccagtat attttcatat agtaactcat ataaaaagtg ttctacttta ctatgatgat 5868 0 gacgatttat aaaaggctta taatgactac ttctcctttc attctcgaat ttcacgataa 5874 0 tgatagagat aatcattatc aattgatagt atcagtaatt ttgacttaca tcacactttc 5880 0 atggtttaat caggtgattg atttaatgaa aagagtgtgt ttgtggatgt attgtgtata 5886 0 tgtcctaccg ggcatctgtt cttacattaa ttaatatatt gctatttaag tattggtagt 5892 0 attgtcagta acattctttt ggttaattta gttattattc ctcactgatt aattgtcctt 5898 0 ccgttcttat tgtttgtaac ttgtgtttgt atcgtacctt tcaggtgttg atgcgcgctt 5904 0 tactgtgtct gcaccggctt gacaaaattc aacaggggtt gaaaaggaac atttcgtgca 5910 0 aataaccgaa gccttaattt cagagccggg ggaaatccgg cgttttgttc agcaggcggt 5916 0 ggaccactgg ccaaatctgt tggcatttca cttcacgctc tattcggcag aaggaatcta 5922 0 tggtcaacag attcagacat tttgtagttc ctttcaccga cgggtacacg aacgtattac 5928 0 ggagcataat cacacggtca gcccatcagc gccggtggta ttacgctggt tgcgggaaca 5934 0 acatgaagga gcacagatac gatgtctgtt gctgctcagc cagacgagta tttgccatcc 5940 0 gcgagtcggc gtcatggctg atgaagaatg tgcgcaactg gtggatttac tgcaacagac 5946 0 ctggtcggtg ataagtgctg gcggacaatg ccgggtggaa agatgttttc gggtggcccg 5952 0 gcctggttca tcagggcaat acgtggcgtt aaaaacggct gttcagtcct ttatgtcgca 5958 0 ggttattgca acaatcatcc ggtgattgtc gggaggaata tcaatgcttc cgttaatttt 5964 0 tactggctga taaagttttg tctgctgaat ctttatacgg aattcctttc agtatgcgta 5970 0 cacgaattga ctatctggcg gataaatact gttttacaga acggaacgaa tccccccgtc 5976 0 ttcgccggca gtggcaggat gttctggagg agtgccggca gacagaggcc gggccagaag 5982 0 aacggttgcg tattgcactg ctgaatgtgg attacgtcac cagttttgaa ctgccttttc 5988 0 gcttgctgct tacccgtaca ccgcaattga ttgccgcgct gcgtgaagaa tggggcatca 5994 0 gccagaaaaa tgtggtgttt aacgataaac ggtttggctg cgtgtacagc ctgaaggcca 6000 0 gcctttctgg tgtgccggat acataccggt atcatctgtc tcaccgtatt cgtcgcgtgg 6006 0 ttgggaatga aaacacatca ttgccatatc agcaggttgc ccgggaagtg aaagcgcccc 6012 0 gtgaacggct gaagtatgca ctggaggcgg gtttactggt gactgcactg gacggcctgt 6018 0 tcaggtttgg cagtcagcgt attgcggctg atgttctgag gctgagaaag gccggaatgc 6024 0 cggtggtgac cacgaccgtg gaggtgcacg ataacctgac gggaacaacc cgcaaagtac 6030 0 cggcatacca tctctgatac aaccatcagg gggaatattg ctctggcagc agcagtatga 6036 0 cattctttat actttatccc cgtgcctgaa aacatgtgct aaggaaacgg gaatggcaag 6042 0 gtccgattat gatattatca atctgtctct ggaacatgaa ctgaatgagt ggctggcaga 6048 0 gagaggttat gccggactgg tggataaccg gaatcgcctg gcagaagttg ttacccgcaa 6054 0 attgcaggac agcttttata taaacgtttc cagggatgcg ctgaacacgg catacagtga 6060 0 acacccggag tggttttctg ggcttgtctc cggggatgag aattaataag tggattatgc 6066 0 tgctatcagg tagtgtgatt gccggcaggg atttcgtttt attctgtttc ttcccggggt 6072 0 tcgggtttga attttcccag aaagttgtac atcggtcgca tgcagggatg cggatagccg 6078 0 tcctgcataa acaccacccg ggtttcctca acactggtca gggtgacaag cgcaccatga 6084 0 tcgtctttgt atcgctgatt gactttcggt aatggaacat cttctgacat aaattttagt 6090 0 acggtaacag ttaactaaat tttcatgtgg tagcactgaa tcaggagact gcgtttcctg 6096 0 atgtgcgctg ttaattttct gtttttacga aacattttcc ccttcttcct gtgtatttta 6102 0 ttgcgctcct cctttcatgt ccttcccata tcctgaaact cacttaaatg ctgttgaatc 6108 0 gtcaaacatt gcaactttca atgactgaaa tcaaaaattg ctatttttta agctaaccaa 6114 0 ctgtattaaa agcattcagt ggaataattt tctgcacttt tccagtaatt atggttataa 6120 0 attttgtaat gtgctgtttt tgcgatattt gtcagaataa agaactgttc atttgtgtta 6126 0 tatcgatcga taaatctgtc atgttgctgt agttcagatc attattctat aatgatcaaa 6132 0 attaagtcaa ttctagctgg tttgttactc agcattctgg taccggttga tgcgggtaaa 6138 0 taccggaagg gcggtagcgt gccatcgcaa aacatggtgg gaggtatcgt caggaggctg 6144 0 gtgaaccgcc ccggttttcc tggagagtgt tttatctgtg aactcaggct gccagatcat 6150 0 cgtttctgat ggaagcataa taagcttttt ctgcttctgc cggagggata tgacccagcc 6156 0 ttcccagcaa tcgtcgattg ttataccagt ccacccacgt gagtgtggcc agttccactt 6162 0 ctgcacggtt tttccagctc ttacggtgta ttacctccgc tttgtaaaga ccattgatgc 6168 0 tctccgccat cgcgttgtca tacgagtcac ctgtactccc tgttgatgcc agcagttttg 6174 0 cttcttttag tcgctccgta taggccagtg atatatactg agaaccttta tcactgtgat 6180 0 ggactgtgcc ggacggccga cgggcccaca acgcctgctc cagtgcatcc agcacgaatg 6186 0 tcgtttccat agacgatgag actcgccacc ccacgataca tccggcaaac acatcaatga 6192 0 tgaacgccac atagacgaag ccctgccatg tgctgacgta agtaaaatca gccacccaca 6198 0 gctggtcagg acgttctgcc acgaactgac ggtttacgcg gtcgcctgcg gaaacggctt 6204 0 tccggctgac ggtagtacgg acctttttac cccggagaac accggcaagt cccataaccg 6210 0 ccatgaggcg cgccactgta catctggcca ccctgatacc ttcgcgtaac aactggcgcc 6216 0 agactttacg cacaccgtac acctgatgat tttcatcgta tacgcgctgt atctctctct 6222 0 tcagccagtc atcgcgctga gcacgggcac tgcgtttatc aggatgatgt cgctgttgct 6228 0 gacagtggta atacgttgac ggggcaatat gcagttcact gcataccggt ccgaccccgt 6234 0 actgctcatg cagcttatcc agcagcggca ttattttttc cagaggcggt cgaactccgc 6240 0 cttcgcaaaa taagcggaag cctggcgaag gatatcgtta ctgcggcgca gttcacgatt 6246 0 ttcacgttcc agctctttca gacgctgacg ttcagcggtg gtgagtccac catcaccact 6252 0 cccggtatcc cgctcatgct gacgaaccca cacacgcaga gtctctggtg tacagccaat 6258 0 ctttggggca atggaacaaa ttgccgccca ttgtgagtca tattcgccct gactttccag 6264 0 aaccatacga actgctcgtt gacggacctc gggggaaaaa cgtgtatttt tagtcatcct 6270 0 gtttacctct ttctcaggga gtttagtctc caggattccc ggggcggttc atggtgattg 6276 0 ttggtatgac atgaataaaa ggtttttcgt ttgactggaa aattatgttg caggaacgag 6282 0 aggactgagg aacaaagctt attccggcgc tgtccgtcct tgctgtcact gacactgatg 6288 0 tctgctttat tatcgccttt atctcttcag gcagcggatg tccggcgtag cggagatgaa 6294 0 gcatttatca ttcagcagca gcgtcaggaa gcccttgagc aacaactgac gccttcagcc 6300 0 cctgatgttc gcctttctgc acctggctct tttgcccata agattaattt tcctgttgaa 6306 0 acgccctgtt ttcagattaa acagacggaa ctgaaggggg ctgatgcgtt accacactgg 6312 0 ctgcctttac aaaaaatcgc caacggggcg gtcgggcatt gcctgggggc gaaaggaatt 6318 0 aatctgctga tgagtacatt gcagaaccgt ctggtcgatc atggttatgt caccacccgt 6324 0 gttctggcac cttcgcagga tttaaaaagc ggtatcctcc ggctggttat tattcccggt 6330 0 gttgtgcgac atgtgcgtct gacaccggac agtgatgact atattcagtt gtattcctca 6336 0 ttcccggcac acgaaggttc tctgctggat ttacgggaca ttgagcaggg gctggattta 6342 0 ggtaacagcc ggatacaggg acaacatact gagctgaatg caaccagtgg aaatctgtct 6348 0 acacagaatg cgcaactgag tgccgatacg ctttccgccc ggactgccgg gcagttcagc 6354 0 agtaatggcg gtacgataaa tgccgacaca ctgcagatat cggcacaaag cctgtcaaat 6360 0 cgtaaaggca gtctgattca gacgggaaca ggggattttt cgctgagtct gccgggaagc 6366 0 gtggataacc gggaagggct gcttgcggca aatggcgcgg tgcgtctgga tgcactgagc 6372 0 cttgataatc gcaaggggaa agtgcaggcg gagcagtcac cctcccttca gaaatccccg 6378 0 cccacgtttc tgaaaccgtt tgtggctggt gtctgtgcgg cattgctggc ggtcagcgtg 6384 0 gctattccgg gatggcagtt tctgacacag ccatcaccgg aggagcagca ttttacctgg 6390 0 gggaatggtt gtaaaaagca gtgaaaacag taaatacaga gtatcgtgat gaattagtgc 6396 0 tcaggggcta ccagtattca ataaccagcg tatcggcatc gcattcctgt aattctggta 6402 0 ttgactgtta tgactaaatt caatgtatat atggcaggca gaaatatgtt aacagtcccg 6408 0 gagttgtgga aaatcctccg gagctaatat cgggagtgcc ttaacaattt tccgtaagtt 6414 0 aaatgataat ttctgagtaa gaatatggtc acgatttgtg ttgacggtga aaataagact 6420 0 cataaaatta ccgactggac gctgtgggct ggaaatgacg acagagaggt tatgctgacc 6426 0 tgtcattttc gcagcgggag aaaatatact cgtccgcttt ctgtatgtca gataacgcca 6432 0 actgtaaatt tgcgaaatgt tttcctcgaa aggaaaggga acgctgtaac atcccgggct 6438 0 gaactggtta ttatatatgg tgataaatat gctgctgttt attaccgcga gggtgaacga 6444 0 ccctacatca tgaaaacgac cggccttgac tttcaacagt gttcagcatt tacagagcat 6450 0 gccgtgttta attacttgtg tagggtggct aatgaacgta ttttttatgc ccgtggtaat 6456 0 aacagaaata tcgatgagaa tatccttagg cagataaaga aaatagttcc tcatccggat 6462 0 accgccttgc atgcatactg ttcaggacag agtaaaaacg tgattcgcca tggggtttga 6468 0 tttttccgtt tggtcttaat gaaagtcagt tgctggctgt cgaacgggca ttttcctcac 6474 0 agatttcagt tattgaagga ccacctggaa caggtaaaac acagactata ctcaatattg 6480 0 ttgctaatat attaattcag aataaaacag tggcaatttt gtccaataat aactcagctg 6486 0 tcagtaatgt ttatgaaaag atggacaaac agcaactggg atatgtgatg gcacgactgg 6492 0 ggagtacgga gaacaggcaa cagttttttt caacgtcgat ttcgcgttct gaggaagtct 6498 0 tacctgactc accgtctgca aatgcgattg atgatgtact tcaacaagtg aaaaaacacc 6504 0 tgaatgccat taaccaggtc gcttcgttaa aagcagaaat taatgagctg aatattgagt 6510 0 ataaatacct gcagcaatgg cagagtcaga atcttcgacc ggaggagctt ttttctcaca 6516 0 aataccgatt ttcctcacaa aaaacaaccg acctgatggc ttatattcat tacctttctg 6522 0 acaggcggat tggattcaga aacagaattg atttgttgtt aaacttcatg atactgaaag 6528 0 tcaaaccatt gatgattccg gagagaaggc tggcgctatt tacttctctt cagctttctt 6534 0 attatgaaaa aaatatccgg gaaaaacaaa tttctctgaa tgaatatgag gaagcattta 6540 0 aaaaatctga ttttaaaatt ttactggggc gcctgacatc atggtctatg ctttatttaa 6546 0 agcaacatct gcgaagaaat gtttcaacaa gaagttcatt ctcggcagag acatacaggg 6552 0 atgaatttga ccgttttata aagcgttttc cgattattgg tagcagtacg cattcgatta 6558 0 ttaactctat cggcaagggg gcccttcttg attatgttat tattgatgaa gcctcgcagc 6564 0 aggatattgt tccgggcatt ctgggactgg gatgtgcccg taatgtaatc gttgtagggg 6570 0 atcgtaagca acttccacat gttcctgtat tactcccgaa cagcccatct ccaccggcag 6576 0 aatactataa ttgtgagaaa tatagtctac ttgattcggt ttgtatgttg ttcaggaaca 6582 0 tggtgccagt aacccttctt aaagagcatt atcgttgtca tcctaaaatc attcaatttt 6588 0 gtaataagca gttttatgat aatgctctga taccgttaac ggttgattcc ggtgaagcct 6594 0 cattatctct ggtcatcacg gcaaaaggaa accatacccg taatttttca aatctcaggg 6600 0 agcttgaatc tctggaaggt cattactggg atgaagaaag tagcagggga tacattgccc 6606 0 catataatgc acaggttaat ctggctgaaa aagtgctgcc tgctgatttt gtgaaatcga 6612 0 cggtgcataa atttcaggga cgggagtgcg atgaaattgt gttttccact gtgctggata 6618 0 agaagcgcag cagccagcac agtcggaaca tcgcgtttgt tgataatcct gaactggtga 6624 0 atgtcgctgt ttcaagggcc cgaaataaat ttacgctggt gactggtaat gatgtatttg 6630 0 aacgccacgc tggacatatt gcggcgctga ttcgttacat caaatactac gctgatgacg 6636 0 gagagatttt cgagagcccg gtcatatcag catttgattt gctgtacagt gagtatgaca 6642 0 aatcactgga acgactgaat agtagattga attcaaatga ttcacacttt aagtcagaac 6648 0 agattgtggc ctgcctgttg cgggatatcc tgtcgcagga tagttatcgg agtatgatgt 6654 0 ttcattcaca aatagcgctg aatcagttgg tgttgctgga gcggggggat tttacacacc 6660 0 gtgaacagtt attcatgcgt aaccgggcca gttgtgactt tgttgtttac tataaggtcg 6666 0 ggaagactcc attaggggtt attgaagtgg atggaggtta tcatctgacc agtgttcagg 6672 0 ctgaacgtga tgaacttaaa aacagtatac tgaagaaatg cggcctgcca ttgctaagat 6678 0 tacgtactat agacagtgat atagaaggga agttgggagc gtttctgtca ggcctgacag 6684 0 gctaaaatct gaataaaaaa tattgcagcg ggaggtctca aacctgattt ggtcatgtgc 6690 0 cacacacaat tgtacgaacc ccatggacac aggcttcttt gttttggtta catcaacgta 6696 0 cgtattcctg atacatataa aaataagtgc tattgctcaa agctaacagg gaatgtttct 6702 0 gttgaataat tccttagtga ataaacttta tcagggggta attctattac agtgaatact 6708 0 tcctgcaaaa tgatatttga attgttcacc atctgcatca tattttctta tttacaagtt 6714 0 gaaaggatag tatatgttga aaatgcatgg attttccagg tgtgttacca gtaagaagca 6720 0 ggtggataaa ggatgtgata acaaatccaa caaccaggtt aatatctgaa gatttttgtt 6726 0 gttattattt atccccaaag cggtgagtta ttaatgaagt ttgcctgaat gtataaacag 6732 0 aattattcga cataaagcca ggaaaatgag tgatacgctt ttaaccgaaa aaatccttac 6738 0 cggagaaaat gttttgcgtg ctgcaatcgc ccgcattgag tggatttttg aaacatttcc 6744 0 gtcggtatgt ctgtcttttt caggtggaaa ggattccacc gtgcttttcc atcttgtggc 6750 0 agaggtggcc cgcaggagaa aacgtcattt ctctgttctg ttcattgact gggaggccca 6756 0 gtatcggtgc accattgaac atattcagaa gatgcgggaa atgtaccatg atgtgacgga 6762 0 aaccttttac tgggtggcac ttcccctgac cacggtaaac ggcgtctcgc agtttcagcc 6768 0 ggagtggata tgctgggagc caggagtgac ctgggttcgc cagccaccgg aagaggccat 6774 0 tacggatatg acatattttc cctttttccg gtatgccatg acgtttgaag aatttgttcc 6780 0 ggcattttct tcctggtttg ccggtaaccg gtgtggagtg gcagtgctga ccggtgttcg 6786 0 tgcggatgaa tccctcaatc gctttatggg gctggtgtct cagcgcaaac tgagatatgc 6792 0 cgatgataag ccctggacca cggcatcgcc tgaagggttt tattacacca tgtatccgtt 6798 0 gtatgactgg aaagcccgcg atatctggat atataacgcc agagcttgtg ccatttacaa 6804 0 tcctctgtat gacctgatgt accgtgccga cgtgccgtta cgcaacatgc gtgtctgtga 6810 0 accttttggt cctgaacaac gtaaggggct gtggctttac catgttctgg agccggaaac 6816 0 ctgggccagg atgtgtgagc gggtgtcagg cgctgccagc ggggcgcttt atgccaatga 6822 0 aagcggtgcc tattttgccc tgcgtaaacg tatatcaaaa ccagcccatc atacctggcg 6828 0 cagctatgcg atgttcctgc tggatgtgat gccggaaaga acggcagaac attaccgtaa 6834 0 taaaattgct gtctacctgc gctggtatca gacgcggggc ttcccggatg acatcccgga 6840 0 tgaacaggag aatgacctgg ggagccggga tattccgtcc tggcggcgta tctgtaagac 6846 0 acttataaag aatgatttct ggtgccggcc cctctccttc agtccgaaca aaccccggca 6852 0 ctatgaacgt tatctgcagc gtatgaaaga aaggaggaag gaatggggga ttctgtgaca 6858 0 ccggagataa ttggcaacat gattcgtcag tacttcagcc aggaacgacc agaagaagag 6864 0 accatacagg cccttaatca cctgcgcaga gtgcttcatg aagtcagtcc ttttgcacat 6870 0 gagccagtgg actgtgtgct gtgggtaaaa gcagatgagg tggtggccaa tgattacaat 6876 0 cctaatgtca tggcgccggg tgagaagaaa ctgctgaagc agtcactgga gaaagatggt 6882 0 ttcacacaac cggtggtggt gtctgaggaa aagaaccatt acctggtggt ggatggtttt 6888 0 catcgccagg tgctgggcag ggaagcaggt acgggaaaac gtctgaaggg ctggctgccg 6894 0 gtggtctgta ttaatccgga gagaaaggga caggcctcac gtattgctgc gaccatccga 6900 0 cataaccggg ccaggggcaa acatcagata acctcaatgt ctgatattgt cagggacctg 6906 0 tcgcgcctgg gctggacgaa tgaacgcatt ggtacggagc tgggtatgga ccaggatgaa 6912 0 gttctcagat tgaaacagat tagcgggctg acggagctgt ttcaggaaga ggatttcagc 6918 0 ccggcatgga cggttcgctg agaccgtcag atatgtatat tatttcagtg agttaatgtt 6924 0 ttgagcagga aaaagagtac cccggaagtt gtggaagaca tggttgcgca gaaactggag 6930 0 gctgctggtt gctggcgcag agcttctgac cgctggcttt ttgttatggg aaatgttgaa 6936 0 tgtacagaag cacaacggga gtggttgttg ttgcgccgga attattgtct ggcgcagata 6942 0 tcgtccccgc cgctacctga aacgctggat atcagcgagg tggcgaaagc tgcagatgcc 6948 0 acgctgaggc gaatggggat tgccactccg tccggggagg tattcagaaa aggtacaccg 6954 0 gtctgttgat attcaggtaa caggtattaa tgatgaagca aggaatggca aacagtatat 6960 0 caatgacatg gcaactttta tgcgatgaac atggttttac ccgggagcac tacaatcagc 6966 0 tgaagaagtt cagcccggag acattacgtg aaattattgc tgaaatagcc agctgtcatc 6972 0 catcaaccag tgtattgctc aggaataagt ggctgacacc gccggaggat attctggagc 6978 0 agattacccg tgaatacgaa cgaagaatac aaaactgtcc accgttcagg agcgagaagg 6984 0 aagcggaatc ctggttaaat gaactatctt ttgctgtgat tgctccgcta taccgtgttg 6990 0 cccccgaaca aacagaacag gttgagtcct ttgttctgca gcttattgcc gagcaggagc 6996 0 gggtttggga gcttatttta accaatgatg gttattcatg gcattgcgca ctttatgata 7002 0 tattatttca tctggtttta cgaaatatgg aagaccagcc tgaacatcag aaacagcgaa 7008 0 taacaaaaat attttatgag cccgatgcaa gactggttgc agaagagatt aaattccgga 7014 0 ttcaatctct gtatgatgat gaacaaaaga gagctttaag tgaactggta aatgatttta 7020 0 cttcaaaaga ataaaatgcg gcgaggtgat ttttactata tgttaataaa acggggggta 7026 0 gatgaaagtg aatggtgtta ctacatcaaa atatgaagga tggcgaggga cgtttcagtt 7032 0 atatagatat aaaacggtag ttctggtgca ccccaaagga tatctggcag gggaaatgat 7038 0 tcatcgccag gccctaacgt cgtcttgtca agattaatgc tatagacata gctaaatttt 7044 0 ttatggataa ggatatgaac tgtgcctcag gtccggaaca tcctgtaggg actttttaag 7050 0 tcgggattga gctgaactaa tgccaaatta tgaacaggga aattcagcag cggctacagt 7056 0 gggtaaaact ctatgaaacg tccggtgatg cgggatttgt atgccgtcgc tgtggcattt 7062 0 ctcggcccac attgcgtaaa atggtggcgc agatatctgg ctcagggcat cgctggtctg 7068 0 gaaagccaca gccgtcgccc caagcgttca ccatcaacga aaaccggcac ttgcgaagtc 7074 0 gctctgattc tggagttacg ttctcagcga aatctggggg caagacgtat tcaaagcgag 7080 0 ttaaaacgac ttcattcaat ctcactggca atagcaacaa tccacaaagt ccttttccag 7086 0 aatcaggttt gaaccgcccc gggtttcctg gagagtgttt tatctgtgaa ctcaggctgc 7092 0 cagatcatcg tttccgatgg aagcataata agctttttct gcttctgccg gaggagtatg 7098 0 gcccagcctt tccagcaatc gtcgattgtt ataccagtcc acccacgtga gtgtggccag 7104 0 ttccacttct gcacggtttt tccagctctt acggtgtatt acctccgctt tgtaaagacc 7110 0 attgatgctc tccgccatcg cgttgtcagt aagcgtaaac tgaccgccgt atgtagccat 7116 0 cagacgaaaa ttggtaactt agacgcccat ctgatataga cggacatcta agtatggaat 7122 0 tacaggactg gcgaaaagaa cctcgtaaaa actattcgaa tgaattcaaa cttcgtatgg 7128 0 tggaactggc atcacaacca ggagcctctg ttgcccgtat tgcccgggaa cacgatatca 7134 0 atgataacct cctgttcaaa tggctcaggc tctggcagaa cgaagggcgt atatcacggc 7140 0 gtcttcaggt aacgacctct tctgacactg gcgttgaatt attacctgta gaaataacgc 7146 0 cggatgagca gaaagaaccg gtggcggcca ttgcgccgtc tttatccact tccactcaga 7152 0 ccagtgtcag tgccggctcc tgcaaggtgg agttccgtca cggtaacatg acgctggaaa 7158 0 atccatcgcc agagctgctc acgctgttga tccgtgaact gaccgggagg ggacgatgat 7164 0 ctcactcccg tcaggtaccc gcatctggct cgttgccgac gttaccgata tgcgtaaatc 7170 0 cttcaacgga tacgacatat gctgaaggag gagcagtaat ggattaagtg ataacaaata 7176 0 cccagaaata gaggttcaaa tccagcttag ttagtacata aatactattt tgatgaaaat 7182 0 tattatatgt ttcctcagat tttaatcagg cgcccagatt aaaccaagta ttgagcgcct 7188 0 gattatgttt attcattaat atctgtcatt gattgtctta ttatcagcta tccccgtatt 7194 0 aatcagagtt ttcatttatt tttaatgcat aatcagatgc cgcctcatca ttatcctcag 7200 0 tattatcata gccgaaaact tctcccggac acgggcgttc acgataatag tcatcgtcat 7206 0 agttttcatc gtcagataat gatatgtcgt attctgaata tgattcacca caattataca 7212 0 tgaaatcatc tcctttgggg ggggcaataa ttagtgagtt tattcgaaaa aatgatgagc 7218 0 gccagaccaa tccacccaac ttttgattat aatcatgaag atacttgtct cagtacaaat 7224 0 tgaatcaaac tcaatgcagc atgattcacc tttatattct ctcagggaaa ccaaatacca 7230 0 ctactcaact attaagaaca aaattcggga tgtatgatta tcagaagata cctgcatcct 7236 0 aaataatttc agacagatat tatcgttgtg aatcccccgc cacctttccg gtgcgcgggg 7242 0 ttttgtcttt tttcaccggg aatacatgta tgaatccgtc tgatgccatt gaggcaattg 7248 0 aaaaaccgct ctcctccctg ccttactcgc tttcccgtca catcctggaa catctgcgca 7254 0 aactcaccag tcacgaaccc gtgattggca ttatgggtaa aagcggggcc ggtaaatcct 7260 0 cactctgtaa tgcactgttt cagggggagg tcaccccggt cagtgatgtt cacgccggca 7266 0 cccgggaagt gcggcgcttc cgtctgagtg gccatggtca cagcatggtt atcactgacc 7272 0 tgcccggggt gggcgagagc cgggacaggg atgcagagta tgaagccctg taccgtgaca 7278 0 ttctgcctga actggacttg gtactgtggc tgattaaagc cgatgaccgt gccctgtctg 7284 0 tggatgagta tttctggcga cacatactgc accggggaca tcagcaggtg ctgtttgtgg 7290 0 tgacgcaggc cgacaaaaca gagccctgcc atgaatggga tatggcaggt attcagcctt 7296 0 ctcccgcaca ggaacagaac attcgcgaaa aaacagatgc ggtattccgg ctgttccggc 7302 0 ccgtacatcc ggttgttgcc gtatcggccc gcaccggctg ggaactggat acgctggtca 7308 0 gtgcgctcat gacagcgctt cccgaccatg ccgccagtcc cctgatgacc cgcctgcagg 7314 0 acgagctgtg cacggaatct gtctgggggc aggcccgtga acagtttacc ggtgcggtgg 7320 0 accggatatt tgacacggtg gagagcgtct gtgttgcctc tgttgcacgc acagttctgc 7326 0 gtgccgtccg tgacacggtg gtctctgttg cccgcgcggt atggaactgg attttcttct 7332 0 gaacagtctg ccaggggaaa tgtctgatta cattgcgtta accaactgaa aacatgatac 7338 0 aaacacctca tgcccctcct gtttctcttg cgtgactgct ctactgttaa tagaataaaa 7344 0 cgatcgataa aacaggtatc gatcgtttat atcgatcgtt tatagtggtt aatggcctgc 7350 0 gaaaaggcag ctgaatctct tcatcatgca gaacggaatt gcacacaaca gactgatact 7356 0 tctctgtctg atgaaggggg agagcgttta cgcccgggac gtatcgctgt gcccgataac 7362 0 tctgttttgt acctgccggt atccactttt gtgggtaccg gcttttttat tcaccctctg 7368 0 taaggaaaag ctgatgaaac gacatctgaa caccagctac aggctggtat ggaatcacat 7374 0 tacgggcacc ctggtggtgg cctccgaact ggcccgctca cggggaaaac gcgccggtgt 7380 0 ggcggttgcg ctgtctcttg ctgctgtcac atcagtcccg gcactggctg ctgacaaggt 7386 0 tgtacaggcg ggagaaaccg tgaacgatgg aacactgaca aatcatgaca accagattgt 7392 0 cttcggtacg gccaacggaa tgaccatcag taccgggctg gaactggggc cggacagtga 7398 0 agaaaacacc ggtgggcaat ggatacagaa tggcgggata gccggaaaca ccactgtcac 7404 0 cacaaatggt cgtcaggtcg tgctggaggg gggaacagcc agtgatacgg ttattcgtga 7410 0 cggcggggga cagagcctga acggactggc ggtgaacacc acactgaata acagaggcga 7416 0 gcagtgggtg catgagggcg gggttgccac cggtacaatt atcaaccgcg acggttacca 7422 0 gagcgttaaa agtggcgggc tggcaacagg aaccatcatc aacaccggcg cagaaggcgg 7428 0 ccctgattct gacaactcgt atacgggtca gaaggtccag ggaacagcag aatccaccac 7434 0 catcaacaaa aatggacggc agattatctt attttccggg ctagcccgtg acactctcat 7440 0 ttacgcaggt ggtgaccagt cggtacacgg aagggccctg aataccacac tgaatggcgg 7446 0 ttaccaatat gtgcacaggg acggacttgc gctgaacacg gtaattaacg aggggggctg 7452 0 gcaggttgtt aaggcaggtg gcgctgccgg taacaccacc ataaatcaga acggtgaact 7458 0 gagggtacat gccggcgggg aagccactgc agtcacccag aacacgggcg gtgcactggt 7464 0 taccagtact gctgcaactg tcatcggcac aaaccgtctg gggaatttca cggtggaaaa 7470 0 cggtaaggct gacggtgttg ttctggaatc cggcggtcgt ctggatgtac tggagagcca 7476 0 ttcagcacag aataccctag tggatgacgg cggtaccctg gcagtgtctg ccggcggtaa 7482 0 ggcgacaagt gtcaccataa catccggtgg tgccctgatt gcagacagtg gtgccactgt 7488 0 tgaggggacc aatgccagcg gtaagttcag tattgatggc acatccggtc aggccagcgg 7494 0 cctgctgctg gaaaatggcg gcagctttac ggttaatgcc gggggacagg ctggcaacac 7500 0 cactgtcgga catcgtggaa cactgacgct ggctgccggg ggaagtctga gtggcagaac 7506 0 acagctcagt aaaggcgcca gtatggtact gaatggtgat gtggtcagta ccggcgatat 7512 0 tgttaacgca ggggagattc gctttgataa tcagacgaca ccgaatgccg cgctgagccg 7518 0 tgctgttgca aaaagtaact ccccggtaac gttccataaa ctgaccacca cgaacctcac 7524 0 cggccagggc ggcaccatca atatgcgtgt tcgccttgat ggcagcaatg cctctgacca 7530 0 gctggtgatt aatggtggtc aggcaaccgg caaaacctgg cttgcgttta caaatgtcgg 7536 0 aaacagcaac ctcggggtgg caaccaccgg acagggtatc cgggttgtgg atgcacagaa 7542 0 tggcgccacc acagaagaag gtgcgtttgc cctgagtcgc ccgcttcagg ccggcgcctt 7548 0 taactacacc ctgaaccgtg acagcgatga agactggtac ctgcgcagtg aaaatgctta 7554 0 tcgtgctgaa gtccccctgt atacatccat gttgacacag gcaatggact atgaccggat 7560 0 tctggcaggc tcccgcagcc atcagaccgg tgtaaacggt gaaaataaca gcgtccgtct 7566 0 cagcattcag ggcggtcatc tcggtcacga taacaacggc ggtattgccc gtggagccac 7572 0 gccggaaagc agcggcagct atggcttcgt ccgtctggag ggtgacctgc tcagaacaga 7578 0 ggttgccggt atgtctctga cgacaggggt gtatggtgct gcaggccatt cttccgttga 7584 0 tgttaaggat gatgacggtt cccgcgccgg cacggtccgg gatgatgccg gcagtctggg 7590 0 cggatacctg aatctggtac acacatcctc cggcctgtgg gctgacattg tggcccaggg 7596 0 aacccgtcac agcatgaaag cgtcatcgga caataacgac ttccgcgccc ggggctgggg 7602 0 ctggctgggc tcactggaaa ccggtctgcc cttcagtatc actgacaatc tgatgctgga 7608 0 gccacaactg cagtacacct ggcagggact ctccctggat gacggccagg ataacgccgg 7614 0 ttatgtgaag ttcgggcatg gcagtgcaca acatgtgcgt gccggtttcc gtctgggcag 7620 0 ccacaacgat atgacctttg gtgaaggcac ctcatcccgt gacaccctgc gcgacagtgc 7626 0 aaaacacagt gtgagtgaac tgccggtgaa ctggtgggta cagccttctg ttatccgcac 7632 0 cttcagctcc cggggtgaca tgagcatggg gacagccgca gccggcagta acatgacgtt 7638 0 ctcaccgtcc cggaatggca cgtcactgga cctgcaggcc ggactggaag cccgtatccg 7644 0 ggaaaatatc accctgggcg ttcaggccgg ttatgcccac agcgtcagcg gcagcagcgc 7650 0 tgaaggctat aacggtcagg ctacgctgaa tatgactttc tgattatacg gtatcccgga 7656 0 aatacgattt caggaaaatt catgcagtaa tgggaaagga cgctcattgc tgttcaccgc 7662 0 agttctgaat tattgaattt ataaaggtga atgatgcacg aaaagaacat cgccctgctt 7668 0 tgtgatgaag ccgaccggct tttgcaactg aatatcaatc tgctccggca aatggttgat 7674 0 gagccggatg tgttatctga cagtaagaac gaaaacgggc tgctttttga taaacggaaa 7680 0 gcgctgaaaa gaattgagga gctggagggc gaacaaatca aaaccgcccg cagggagatg 7686 0 gtgctggctg tggtcggcac gatgaaggcg ggcaaatcaa ccaccatcaa cgccattgtg 7692 0 gggcaggaaa ttctgcccaa ccgtaaccgc cccatgacct cggtaccgac attgatccgc 7698 0 cacgttcccg gaaaaacgga accggtcctc catctggaac atattcagcc cgtccgcaat 7704 0 ttattaatca cactgcagga aaaactcgcc accccggcag ggcagcaagt cgcacagtcc 7710 0 ctgcagcaaa ccggggatac ccgcgaacta ctggatattc tggcggatga tgtctggctt 7716 0 aaaaatgaat accacgggga agacgaaatc tttaccggac tggcatcgtt aaatgacctg 7722 0 gttcgtcttg ctgcggcaat ggggactgaa tttccttttg acgaatacgc agaagtgcag 7728 0 aaactaccgg tgatcgacgt ggcgttcagc cacctggtgg gaatggatgc atgtcaggga 7734 0 acactcacac tgctggatac ccccggccct aatgaagccg gacaaccaca gatggaaatg 7740 0 atgatgcggg atcaactaca gaaagcctct gcggtgctgg cggtgatgga ttacacccag 7746 0 atgaactcga aagccgatga ggaggttcgt aaagagctta atgccattgc tgacgtctca 7752 0 gccggtcgtc tgtttgtgct ggtcaataaa ttcgatgaaa aagatcgcaa tggtgatggt 7758 0 gcggatgccg tacgccagaa ggtgccagca atgctgaaca gcgatgtgct gcccgcctcc 7764 0 cgcgtttatc ccggctcatc acgtcaggcg tacctggcta accgtgcgct tcatgagtta 7770 0 cgaaaaaacg gtgcgcttcc ggttgatgaa gcctgggtcg atgattttat cagggaagct 7776 0 ttcggaccta tggtggaaga ggacgactgg aaagacagca ctaaggtaaa taaaaaggca 7782 0 gaaaaactct ggaatatatc tctgatcgat caactgataa cggaagtcat acagagctcc 7788 0 cattccagag cggcggcact ggcggttgac tctgccgccg caaaactgat gcagaatgca 7794 0 gaaaatgtca gcgaatatct gtcattacgt catcaggggc tgcagcaaag cattcagtca 7800 0 ctacaggcgc atattaccag cctgctggcg gatatccagg agattgagga atgtcagaat 7806 0 caggtgaccg gtgatgtcag aatggccatg gaggacatca ataccaaaac cggggaatta 7812 0 ctgacgaagg tctgtgcctc actggaggag gagctgaacg actatttcag aagcggtaaa 7818 0 cgcaaagaac agcaaatgct ggaggaagaa aattcagcgc agccccggga gagaaacgca 7824 0 ttcgctttct ttcacgatat tttcggaacc ggaaatcagc atgacaggat gcgggacttt 7830 0 gatccggaca gccccgaaat aaaattcagt gatcgcaggg cagcccttga actgatgacg 7836 0 caaatcgaat cgaccgtgac cagcctgcac cgtgaggctg aagcacagtt ccggcctgag 7842 0 ctggagaaaa tcgtcagcgg gattgaaaca ggttttcgtg gcacggccct gtacgccaca 7848 0 gaaaacattg ccggtcgcat caatgcccgc ctggaggatg agggctttac cgtaaaaatc 7854 0 agttttccgg cagtcagcca gttacagacc cggctcgcgg taaaaataaa tctgagtgcg 7860 0 cttatggagg aaagaacgga gaccgtcacc cgtcgccgtc ggcagagtgg cgtatgggga 7866 0 accgtttgtc gatggtttgg caccagtgac ctgggctggg aaaactatga cgaggatgtg 7872 0 agtcgcagcg tgatcaatat caacaaggcc agagaggaag ttatgtcact gacccgggca 7878 0 tatttcgggg agctgcaggc atccattgag caggatatta accagcccgt ccgccaggaa 7884 0 atcgatgcct ttttctgcgc attcagggag aaagttgaac aactgcgtaa cacgctgatt 7890 0 cagagctctg aagatcataa acgcgatcag caggcgcagg aacggcttac cgggcgactt 7896 0 caggcattaa atgaaagggt tcctgagctc attactgaca gtaaggcgct gagggaagag 7902 0 ctggagacaa tgctgtgact tcaccattta ttcaacaaat tgctgataac cgggtatgtc 7908 0 aggtactcac ctgtcttcct gaaaaatttg tggttgattt cgcaaacgga atcgatgttg 7914 0 cacaggagca tatccgcacg gccggagagc gcacgttctt ccggcgttta aaagaggggc 7920 0 tgaccggcga aggcgctgca cggcagaatg ccatcaatgc gtcgcttgca cagggcgttg 7926 0 aggcgtccct gcgctggctg acggagatga caacgtcact tgccaccaca aactacgcga 7932 0 ttacccgggt aaacgacagg gtcagttcac tggtcagtga tacagccagg ctggcgcatt 7938 0 attccgcaga tacgcgggag cagttactca ccctggccga tcaggttcac cataaactga 7944 0 atcatcttga agaaaaactc caccgtgttg accaggttca gcgggcgcag ttacatcttg 7950 0 agcagatatt ctcatggtgg agcgccgggc gatatgcgtc attttcccct gccggacgtt 7956 0 gttatgtggc acttgaagag cttcgctggg gcgcgtttgg tgatgtgata cgtcagggcg 7962 0 aaacaggcca ggttaaccag ctactggata ttctcagaca taaagcatta acgcagatgg 7968 0 cacaggagag tggcggtagt gcaaccgtgc gtctgaacac tctggactgg cttggtggtc 7974 0 agggccggga gcaggcagat aacgagtggc atgacgcgat taactggctg ggagactggt 7980 0 gcagtgaaga gcagcatccg gtgatctggt caaccacgca ggctgcagaa cacttaccgg 7986 0 ttcgcatgcc tcgcctctgc tctgcagaac gcctctctga aagtatggtc gatgaaatat 7992 0 ttcagaaggg ggctgcatga gtacagaaat gaaaacgggg ctggtgctgt ccggtggcgg 7998 0 ggcggtgggc gcttatcagg cgggagtggt taaggcactg gcagagtgtg gtacacagat 8004 0 cagcatggtt tcagggacca gcattggcgc attcaatggt gccattatcg cggcctctcc 8010 0 cgatctgtca gaagctgccg tacgcctgga ggcgctctgg gagcatctgg ggaataatca 8016 0 ggtgctgtcg gtaaacagat tggtttactt ttcattgctg aaaaaattgt tccaggcaat 8022 0 gaacctctgc cagatccccg gacgtgcagg agcactgctt acgacgcttc ttcgccatat 8028 0 atcgacaatc aacgggtttg acaatctgat ggctcagccg ttgttgtcag atgagcccct 8034 0 gacagcgctg atggatcatt atcttgatac tgatgctctg gcagacgggc taccgctgta 8040 0 tgtgtcgctg taccccacag aagggggcat gcaggatatt attgactgca ttcgtgctga 8046 0 actgggtgtc ggaaccacga aaaacgccgt ttttcagcat atccagagcc tgccccgcgg 8052 0 acagcagaaa gaggctctgc ttgcgtcagc cgcgctgccc ctgctgttcc gtccccgtga 8058 0 ggttcagggg acaatgttcg gtgatggtgg tatgggagga tggcgaaata tgcagggaaa 8064 0 tacccctgtg acgcctctgg tcgatgccgg atgcaatatg gtgattgtga cgcatctgag 8070 0 tgacggttct ttatgggatc gccaggcttt tccggacacc acaatccttg agatccgtcc 8076 0 ccggaaaagg ctgaaatatg caggtgatgg tggcaacagc ggcggtctgc tcagttttac 8082 0 atcggcacat accgacgcct ggcgtcagca gggctatgaa gacacgatgc tggcgatgga 8088 0 gcatatccgg aaaccgctgg cagcacgtca ggcactgacc cggtcagagg cggtattgca 8094 0 gaaaagcctg gatataacgg aagaggcaga tttggcactg agaaacgcga tggcccggat 8100 0 taaataaaga cgccccaaag aaacgccacc gcctgtggtg gtgtttttcc tgtctggtgt 8106 0 tattgaaaat attttcagat atatattatc tgggtgatgg ttaagatgaa tttatttaat 8112 0 tttgggggaa gatacaaaaa caaccagtga acatatttcc ggcgggttat ccgcaatgct 8118 0 gaaggtcagt tgcactggcg atgccggaat acagcttaat acgtggttcg ccagtgaagg 8124 0 gcttctcaga caataaacct cattcatttc acccatcagg ccgcgtcttc tccgggagac 8130 0 gcggcttttt catttatatc gcttaatcat tcataaggag caaatcatga gattagccag 8136 0 tcgttttggt tatgcgaacc agatacgtcg tgatcgtccg ctgacacacg aagaactgat 8142 0 gcgccatgta ccgagtattt ttggggaaaa ccgacatacc tctcgcagtg aacactatgc 8148 0 gtacattccc actatcaccg tcctggaaaa tctgcagcag gaaggctttc agccgttctt 8154 0 tgcctgccag acccgcgtgc gcgaccagag ccgccgggaa tacacaaaac acatgctgcg 8160 0 tctgcggcgg gccggacaga taaccggtca gcatgtccct gaaattattc tgctcaactc 8166 0 ccatgacggt tcatccagct accagatgtt acccggatat tttcgtgcca tttgtaccaa 8172 0 tggactggtc tgcggtcagt ctctgggaga attgcgtgtt ccacaccggg gaaatgtggt 8178 0 ggacagagtc attgaagggg cttacgaggt ggtgggcgtt tttgaccgga tagaggagaa 8184 0 gcgtgatgcc atgcagtcgc tggtcctgcc gccaccggca cgccaggcgc tggcacaggc 8190 0 ggcactgact taccgttatg gtgacgaaca tcagcccgtc accaccgccg acattctgac 8196 0 accacgacgc cgggaggatt acggtaagga cctgtggagt gcttatcaga ccatccagga 8202 0 gaatatgctg aaaggcggga tttccggtcg cagtgcaaaa ggaaaacgta tccatacccg 8208 0 ggccattcac agcattgata ccgacattaa gctcaatcgc gcattgtggg tgatggcaga 8214 0 aacgctgctg gagagcatgc gctgatgccg tttcactgaa agtgcagtcc tgactcacat 8220 0 ctgttcctgc cccggggctt cttccattca tttacttttt ataaggaata acctcatgac 8226 0 aaccgtttcg cataattcca ccacaccttc tgtttccgta accactgcat cagggaataa 8232 0 cccacctcag ctggttgcca ctcccgtccc tgatgaacag cgcatcagct tctggccgca 8238 0 gcattttggc ctcattccac agtgggtgac cctggagccc cgtgtcttcg gctggatgga 8244 0 ccgtctttgc gaagactact gcggtggtat ctggaatctg tacaccctga acaacggcgg 8250 0 ggcatttatg gcacccgaac cggatgacga tgatgacgaa acatgggtac tgttcaatgc 8256 0 catgaacggc aaccgcgctg aaatgagccc ggaagccgcc ggtattgctg cctgtctgat 8262 0 gacgtacagt catcatgcct gtcgtacgga gtgttatgcc atgacggtcc actattaccg 8268 0 gctgcgggat tacgccctgc agcatccgga atgcagcgcc attatgcgca tcattgactg 8274 0 aatggaggca gggacaatgc agcagctttc ctttctgccc ggagagatga cgcccggcga 8280 0 gcgcagtctc attctgcggg ccctgcaaac cctggaccgc catcttcatg aacccggcgt 8286 0 ggccttcacc tccacccgtg cggcacggga atggctgatt ctgaacatgg cgggactgga 8292 0 gcgggaagag ttccgggtgc tgtatctgaa caaccagaat cagctgattg ccggtgaaac 8298 0 cctcttcacc ggcaccatca accgtacgga agttcatccc cgggaagtga ttaaacgcgc 8304 0 cctgtaccac aatgccgctg ccgtggtgct ggcgcacaat cacccgtccg gtgaagtcac 8310 0 acccagtaag gcagaccggc ttatcaccga acgtctggta caggcactgg gcctggtgga 8316 0 tatccgggtg ccggaccatc tgatagtcgg tggcaaccag gttttctcct ttgccgaaca 8322 0 tggtctgctt taacccgtca caaccacatc acacctgttt tcacttttat cttctgtctt 8328 0 cagaggtatc acatcatgag aatcatcacc cgtggtgaag ccatgcgtat tcaccaacag 8334 0 catcctgcat cccgtctttt tccgttctgt accggtaagt atcgctggca cggcagtgct 8340 0 gaagcgtata ctggtcgtga agtgcaggat attcccggcg ttcttgccgt gtttgcagaa 8346 0 cgccgtaagg acagttttgg cccgtatgtc cggctgatga gtgtcaccct gaactgatgt 8352 0 tccgtcaccc gggaaacgag tacgaccaga tgacctcaga cgccgctgtg gatgaggcca 8358 0 ttctcatcaa tgcatacatc ttcaccgaaa ccggtcagcg cgccggctga cctgtcatcg 8364 0 ttaaaccatt cttaaccact tttcagagag gattttatcg tgtcagacaa actctccggg 8370 0 ataactcatc ccgatgacaa tcacgaccgc ccctggtggg ggcttccctg cacagtgagg 8376 0 ccctgttttg gcgctcgtct ggtgcaagag ggtaaccgcc tgcattacct tgccgaccgc 8382 0 gccggtatca gaggccgctt cagcgacgca gatgcatacc atctggacca ggcctttccg 8388 0 ctgctgatga aacaactgga actcatgctc accagcggtg aactgaatcc ccgatatcag 8394 0 cataccgtca cgctgaatgc aaaagggctg acctgcgaag ccgacaccct cggctcctgt 8400 0 ggttacgttt atctggctgt ttatccgaca ccagcacccg caaccacctc ataaccccga 8406 0 agctctcacc tttagcacta ccagttacag agaacttaag atgaaaacat tatccgacac 8412 0 acatgtacgg gaggtatctc gctgcccgtc tcccgtcacc atctggcaga cactgctcat 8418 0 ccgactgctg gaccagcatt atggcctcac actgaatgac acaccgtttg ccgatgaacg 8424 0 tgtgattgag cagcatattg aggcaggcat ttcactgtgt gatgcagtta attttctcgt 8430 0 ggaaaaatac gcgctggtgc gtaccgacca gccgggattc agcacctgtc cccgctctca 8436 0 gttaataaac agtattgata tcctccgggc tcgccgggcg accggcctga tgacccgcga 8442 0 caattacaga acggtaaata acattaccct gggtaagtat ccggaggcga aatgatgaaa 8448 0 ctggccctga cactggaagc cgacagcgtt aacgtacagg cactgaacat ggggcgcatt 8454 0 gtcgttgacg tcgatggtat tgagctcgct gaactgatta acatggtctg cgataacggc 8460 0 tactcccttc gtgttgttga tgaatctgac cagacctcag cagaatgcac gccaccattt 8466 0 gctaccctta ccggcatacg ctgcagtacc gcacatatca cggaaacgga caacgcctgg 8472 0 ctgtactcgc tgtcacacca gaccagtgac ttcggtgaat cagaatggat tcattttacc 8478 0 ggtaacggct atctgttgcg taccgatgcg tggtcgtacc cggttctgcg gcttaaacgc 8484 0 ctgggtctgt caaaaacgtt ccgtcgtctg gtcgtcacac tcatccggcg ttatggcgtc 8490 0 agtctcattc atctggatgc cagcgctgaa tgcctgccgg gtttacccac tttcgactgg 8496 0 taaccaggaa caacatgaaa tcattaacca cggaaacagc gctggatatt ctgattgcgt 8502 0 ggctgcagga caatatcgac tgcggatcgg gaattatctt tgacaacgat gaggataaaa 8508 0 cggattcagc agcactgttg ccctgtatcg aacaggcccg ggaggatgtc cgtaccctgc 8514 0 gtcatctgca gcttctgcac cagaaccggt gaagctcact caccagactt cattcctctg 8520 0 acgccagcct gcacagggct agcgttttca tttatctgca aaaaggaata tcgattatgt 8526 0 cagatatcac aatctcccgt ccggaagtgg tcaacgggca tacggacgtt atctgctcaa 8532 0 ccagcattcg ccacattctg gctgtacgaa agagtacact gttgcaaatc gacacactta 8538 0 tccgacaact ggctgaaatc tcggtgctga cggaaagcat cggaggtaaa actgccccgg 8544 0 actgggccat gaaacaggat tttcgctgcg gctgctggct gatggagaaa cccgaaacag 8550 0 caatgaaagc cattacccgg aatcttgatc gcgaaatctg gcgtgacctg atgcaacgtt 8556 0 ccgggatgct gtcattaatg gatacgcagg cccgtgatac atggtaccgg tcactggagt 8562 0 acgataattt tccggaaatc agcgaagcga acattctgag cacatttgaa caactgcacc 8568 0 agaataagga tgaggtgttt gagcgagggg tgatcaacgt cttcagaggg ctgaactgga 8574 0 attacaaaac caattgcccc tgtaaatttg gcagtaaaat tatcgtcaac aatctggtga 8580 0 gatgggaccg gtggggattt catcttatca ccggacaaca ggctgaccga ctcgccgatc 8586 0 tggaaagaat gttgcacctg ttcagcggta aaccaatccc cgacaaccgg ggaaacatca 8592 0 cccttcgtct ggatgatcac attcagtctg ttcagggtaa agagagctat gaagatgaga 8598 0 tgttcagcat cagatacttt aagaagggct ccgcgcatat cacgttcaga aaaccagaac 8604 0 tggttgacag actgaatgat attatcgcaa aacactatcc tgatatgctg gcagtatagc 8610 0 tttgccagta tgctcaaaga tcggaaattg tccgataaga tatgatcgcg gggcatataa 8616 0 accggtttca gatggcatac ccgatggcat actgtctgga agggaaaata aaaaagcgca 8622 0 tgttaaacaa taacatgcgc ttataatc 8624 8 <210> 133 <211> 401 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(174..1376) <400> 133 Met Ala Val Leu Thr Asp Thr Lys Ala Arg His Ile Lys Pro Asp Asp 1 5 10 15 Lys Pro Leu Pro His Gly Gly Ile Thr Gly Leu Thr Leu His Pro Ser 20 25 30 Ser Val Lys Gly Arg Gly Lys Trp Val Phe Arg Tyr Val Ser Pro Val 35 40 45 Thr Gln Lys Arg Arg Asn Ala Gly Leu Gly Thr Tyr Pro Glu Val Ser 50 55 60 Ile Ala Glu Ala Ala Arg Thr Ala Arg Ile Met Arg Glu Gln Leu Ala 65 70 75 80 Ala Gly Asp Asp Pro Leu Glu Ile Lys Lys Ala Glu Ser Glu Lys Val 85 90 95 Ala Ile Pro Thr Phe Ala Asp Ala Ala Arg Arg Val His Ala Glu Leu 100 105 110 Ser Pro Gly Trp Glu Asn Pro Lys His Val Arg Gln Trp Leu Ser Thr 115 120 125 Leu Glu Asn Tyr Ala Phe Pro Gln Leu Gly Ala Lys Thr Leu Asp Ser 130 135 140 Ile Thr Ala Ala Asp Val Ala Glu Thr Leu Arg Pro Val Trp Leu Thr 145 150 155 160 Leu Ser Glu Thr Ala Ser Arg Val Lys Gln Arg Ile His Val Val Met 165 170 175 Gln Trp Gly Trp Ala His Gly Phe Cys Val Ala Asn Pro Val Asp Val 180 185 190 Val Asp His Leu Leu Pro Gln Gln Thr Arg Gly Arg Asp Glu His Gln 195 200 205 Pro Ala Met Pro Trp Arg Gln Leu Pro Leu Phe Val Ala Thr Ser Val 210 215 220 Tyr Thr Asp Glu Pro Tyr Asn Val Thr Arg Ala Leu Leu Leu Met Val 225 230 235 240 Ile Leu Thr Ala Thr Arg Ser Gly Glu Ala Arg Gly Met Arg Trp Ala 245 250 255 Glu Ile Asp Phe His Lys Arg Val Trp Thr Ile Pro Ala Glu Arg Met 260 265 270 Lys Ala Arg Ile Gln His Arg Val Pro Leu Ser Arg Gln Ala Ile Tyr 275 280 285 Ile Leu Glu Asn Ile Arg Gly Leu His Asp Glu Leu Val Phe Pro Ser 290 295 300 Pro Arg Lys Gln Gln Ile Leu Ser Asp Met Val Leu Thr Ser Phe Leu 305 310 315 320 Arg Lys Lys Lys Ala Val Ser Asp Ile Pro Gly Arg Val Ala Thr Ala 325 330 335 His Gly Phe Arg Ser Thr Phe Arg Asp Trp Cys Ser Glu Gln Gly Tyr 340 345 350 Ser Arg Asp Leu Ala Glu Arg Ala Leu Ala His Thr Leu Lys Asn Lys 355 360 365 Val Glu Ala Ala Tyr His Arg Thr Asp Leu Leu Glu Gln Arg Val Pro 370 375 380 Met Met Gln Ala Trp Ala Asp Tyr Val Met Ser Gln Ile Val Asn Lys 385 390 395 400 * <210> 134 <211> 606 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1563..3380) <400> 134 Met Tyr Asn Phe Ile Thr Ile Met Tyr Asp Val Phe Ser Cys Phe Gly 1 5 10 15 Val Leu Ala Lys Asn Gln Asn Ser Arg Asp Ile Arg Asn Ile Lys Asn 20 25 30 Phe Ser Ser His Gln His Ser Leu Gly Asp Met Phe Asp Glu Leu Ile 35 40 45 Asn Ile Ile Asp Lys Glu Gln Val Leu Ser Lys Glu Gln Arg Lys Val 50 55 60 Ile Phe Arg Arg Tyr Glu Asp Leu Tyr Val Lys Leu Met His Tyr Ser 65 70 75 80 Val Phe Thr Asp Lys Thr His Gln Ile Ile Lys Gln Lys Tyr Phe Asn 85 90 95 Asp Ile Val Pro Met Ile Leu Ala Leu Asp Ile Arg Asn Thr Tyr Arg 100 105 110 Pro Asp Asn Glu Met Ala Phe Tyr Tyr His Ile His Ser Phe Leu Thr 115 120 125 Gln Ile Pro Asp Asn Glu Asp Asp Ile Tyr His Ala Ala Arg Thr Tyr 130 135 140 Leu Arg Asn Tyr Val Lys Leu Cys Leu Ser Gly Tyr Thr Pro Ala Asn 145 150 155 160 Ala His Phe Lys Asp Ile Phe Asp Gly Val Tyr Glu Phe Ile Arg Asn 165 170 175 Ile Arg Lys Asn Ser Thr Pro Gly Lys Thr Lys Leu Ile Ala Thr Ile 180 185 190 Asn Thr Cys Lys Glu Thr Cys Lys His Leu Leu Tyr Leu Ser Asn Glu 195 200 205 Asp Lys Glu Lys Ile Ile Ser Asp Leu Asp Lys Val Gln Val Ala Cys 210 215 220 Tyr Tyr Leu Thr Ile Leu Leu Ala Phe Glu Arg Arg Thr Ser Leu Thr 225 230 235 240 Ser Thr Leu Ala Thr Leu Tyr Lys Met Leu Ile Ser Glu Arg Glu Val 245 250 255 Ser Glu Tyr Glu Cys Gln Leu Leu Tyr Leu Thr Asn Pro Ile Asp Val 260 265 270 Met Asn Ile Leu Asn Lys Tyr Ile Tyr Tyr Phe Pro Asn Glu Asn Ser 275 280 285 Pro Phe Tyr Thr Leu Lys Ile Asp Ser Ala Leu Ser Trp Asp Ala Ile 290 295 300 Asp Ala Ile Arg Asp Tyr Ser Ile Ser Asp Ile Tyr Leu Tyr Pro Glu 305 310 315 320 Gln Lys Thr Ile Asn Cys Val Val Glu Ile Glu Asn Ile Val Phe Gly 325 330 335 Gly Tyr Ile Tyr Thr Leu Asn Asn Gly Val Thr Leu Gln Asn Ile Glu 340 345 350 Asn Ser Leu Lys Asp Ser Ser Cys His Tyr Val Leu Asn Gly Tyr Thr 355 360 365 Glu Phe Val Asn Cys Leu Arg Gln Leu Thr Ser Gly Lys Thr Glu Ser 370 375 380 Val His Arg Thr Ile Asn Lys Leu Asn Tyr Glu Lys Leu Pro Phe Gly 385 390 395 400 Phe Ile Ile Ala Ala Phe Ala Ile Leu Lys Ile Ala Phe Lys Ile Lys 405 410 415 Phe Ser Lys Asn His Val Asn Ile Arg Ala Leu Leu Asn Asp Ile Asn 420 425 430 Tyr Phe Met Thr Tyr Gln Gly Glu Ser Ile Asn Leu Ile Ser Leu Asp 435 440 445 His Glu Tyr Pro Glu Ser Cys Leu Gln Asn Asp Thr Asn Thr Tyr Leu 450 455 460 Leu Gly Arg Val Ile Phe Leu Tyr Asn Ser Met Ile Tyr Lys Phe Ile 465 470 475 480 Asn Cys Gln Glu His Glu Thr Asn Asn Ile His Ser Ala Met Ile Asn 485 490 495 Asn Leu Leu Gln Glu Val Asp Ile Ala Leu Gly Lys Ile Asn Asp Ile 500 505 510 Ile Asp Ser Arg Asn Ile Ser Ala Pro His Glu Leu Ala Asn Ile Leu 515 520 525 Thr Arg Glu Lys Ile Leu Thr Thr Arg Glu Lys Lys Gly Asn Leu Ile 530 535 540 Ser Leu Phe Asp Gly Phe Thr Leu Phe His Cys Val Gly Met Ile Thr 545 550 555 560 Phe Leu Ile His Tyr Leu Arg Thr Pro Glu Glu Lys Val Glu Asn Ile 565 570 575 Phe Met Leu Tyr Gly Ala Asp Lys Asn Asn Lys Leu Arg Arg Arg Leu 580 585 590 Ile Tyr Asp Ala Leu Gly Ile Ile Gln Ser Gln Gln Glu * 595 600 605 <210> 135 <211> 146 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3876..4313) <400> 135 Val Ala Leu Ile Cys Glu Leu Asp Glu Gln Trp Ser Phe Val Glu Asn 1 5 10 15 Lys Ala Arg Gln Gln Trp His Trp Tyr Ala Tyr Lys Thr Lys Ala Asp 20 25 30 Gly Val Leu Ala Tyr Thr Phe Gly Pro Arg Thr Asp Glu Thr Cys Arg 35 40 45 Glu Leu Pro Glu Phe Leu Lys Pro Phe Ser Ala Gly Met Ile Thr Arg 50 55 60 Asp Asn Arg Ser Ser Tyr Thr Arg Glu Met Pro Gln Asp Lys His Leu 65 70 75 80 Val Gly Lys Ile Phe Thr Arg Arg Ile Glu Arg Asn Asn Leu Thr Leu 85 90 95 Arg Thr His Ile Lys Arg Pro Ala Arg Lys Thr Ile Cys Phe Leu Arg 100 105 110 Ser Leu Glu Ile His Glu Lys Pro Leu Val His Leu Ser Lys Thr His 115 120 125 Val Leu Leu Thr Gly Val Ile Thr Arg Ala Ser Phe Ala Val Phe Leu 130 135 140 Pro * 145 <210> 136 <211> 99 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4492..4788) <400> 136 Met Pro Asp Gln Ser Gly His Cys Arg Thr Pro Ser Arg Ile Leu Arg 1 5 10 15 Met Pro Glu Leu Ser Gln Leu Leu Gly Ile Ser Arg Ser Thr Ile Tyr 20 25 30 Glu Lys Met Asn Pro Leu Ser Lys Tyr Tyr Asp Ala Thr Phe Pro Arg 35 40 45 Pro Val Arg Leu Gly Ser Gly Ser Val Gly Trp Arg Ser Ser Ala Ile 50 55 60 Asp Glu Trp Leu Thr Leu His Thr Val Pro Ala Arg Ser Ala Val Lys 65 70 75 80 Gly Val Asn Asp Glu Val Arg His Thr Leu Ser Ser Asp Met Thr Met 85 90 95 Ser Arg * <210> 137 <211> 462 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5431..6816) <400> 137 Met Cys Leu Leu Ala Pro Glu Asn Pro Tyr Pro Ile Tyr Ala Leu Pro 1 5 10 15 Pro Leu Val Arg Asn Ala Ile Ile Glu Thr Gln Lys Asn Thr Gln Ala 20 25 30 Pro Leu Ala Met Val Ala Thr Ser Ala Leu Thr Ala Ile Ser Ile Ala 35 40 45 Cys Gln Asn Gln Ile Asp Val Cys Arg Pro Gly Asn Leu His Gly Pro 50 55 60 Val Asn Leu Tyr Ser Leu Ile Leu Ala Asp Ser Gly Glu Arg Lys Thr 65 70 75 80 Thr Val Asp Lys Val Phe Met Lys Ala Phe Tyr Leu Arg Asp Glu Ala 85 90 95 Leu Ala Asp Glu Tyr Ala Lys Leu Val Glu Asn Tyr Ser Thr Glu Lys 100 105 110 Glu Ile Trp Glu Gln Lys Gln Lys Ala Leu Glu Ser Lys Phe His Lys 115 120 125 Glu Ile Arg Ala Gly Lys Asp Tyr Lys Ala Thr Glu Ser Glu Leu Glu 130 135 140 Thr His Leu Asn Lys Pro Pro Val Pro Pro Gln Ile Arg Arg Thr Ile 145 150 155 160 Phe Asn Glu Thr Thr Ile Glu Gly Met Leu Lys Tyr Tyr Ser Asp Ser 165 170 175 Asn Arg Ser Phe Ala Leu Val Ser Ser Glu Gly Gly Val Ile Phe Asp 180 185 190 Ser Arg Ala Met Ser Lys Leu Gly Ile Ile Asn Thr Leu Trp Asp Gly 195 200 205 Gly Ser Leu Phe Ile Asp Arg Lys Ser Ser Pro Gly Ile Asn Leu Lys 210 215 220 Glu Pro Arg Leu Thr Ile Ser Val Met Ile Gln Pro Asp Val Tyr His 225 230 235 240 Lys Gly Phe Cys Thr Arg Lys Lys Glu Ile Val Lys Thr Ser Gly His 245 250 255 His Ala Arg Phe Leu Met Cys Gln Pro Thr Ser Thr Gln Gly Thr Arg 260 265 270 Ile Met Ile Asn Glu Leu Ile Asp Glu Ser Leu Ala Met Ser Gly Glu 275 280 285 Arg Arg Cys Leu His Phe Ser Pro Gln Ala Ala Arg Ile Trp Thr Asp 290 295 300 Tyr Tyr Asn Asp Val Glu Ser Lys Leu Gly Gly Leu Gly Pro Leu Arg 305 310 315 320 His Cys Arg Glu Tyr Ala Ala Lys Asn Ala Glu Tyr Met Ala Arg Leu 325 330 335 Ala Gly Leu Ile Tyr His Ser Ser Gly Glu Glu Gly Glu Ile Ser Pro 340 345 350 Tyr Thr Ala Glu Met Ala Arg Glu Leu Ala Ile Trp Tyr Gly Asn Glu 355 360 365 Tyr Val Arg Leu Ser Asn Pro Leu Thr Phe Asp Asn Ser Ala Leu Thr 370 375 380 Val Pro Val Arg Leu Ile Pro Glu Glu Leu Glu Leu Phe Asn Trp Ile 385 390 395 400 Lys Ser Tyr Cys Ile Glu Lys Gly Ile Leu Cys Met Lys Lys Asn Asp 405 410 415 Ile Leu Gln Arg Gly Pro Asn Arg Phe Arg Lys Lys Asp Lys Ile Asn 420 425 430 Trp Leu Leu Asp Leu Leu Tyr Glu Gln Asn Arg Val Val Pro Val Ile 435 440 445 Glu Gly Lys Thr Leu Cys Val Ala Pro Asn Phe Asp Leu * 450 455 460 <210> 138 <211> 188 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7637..8200) <400> 138 Met Tyr Asn Ala Asn Pro Asn Tyr Glu Met Asp Phe Met Ile Leu Lys 1 5 10 15 Asp Val Asn Glu His Met Glu Gly Leu Phe Gln Arg Phe Ser Lys Leu 20 25 30 Leu Pro Phe Arg Ile Asp Phe Ala Tyr Arg Lys Asp Thr Pro Ser Phe 35 40 45 Gly His Ser Cys Arg His Ser Met Cys Ile Glu Met His Arg Leu Leu 50 55 60 Ser Glu Thr Gln Thr Met Leu Ala Gly Tyr Tyr Trp Val Met Glu Tyr 65 70 75 80 Thr Ser Asn Lys Gly Leu His Ile His Phe Ile Gly Tyr Leu Asp Gly 85 90 95 Gln Arg His Asn Lys Ser Tyr Arg Ile Ser Arg Gln Leu Gly Asp Ile 100 105 110 Trp Arg Arg Ile Thr Glu Gly Glu Gly Tyr Phe His Leu Cys Arg Ala 115 120 125 Lys Asp Lys Tyr Pro Val Arg Ile Asp His Val Ile His Tyr Ser Asp 130 135 140 Lys Ser Ala Val Asp Asp Leu Arg Tyr Ala Leu Ser Tyr Leu Ala Lys 145 150 155 160 Gln Asp Gln Lys Glu His Gly Ile Ile Leu Arg Arg Ser Arg Leu Pro 165 170 175 Glu Lys Ser Asn Arg Gly Arg Pro Arg His Asn * 180 185 <210> 139 <211> 787 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8355..10715) <400> 139 Met Val His Lys Ser Asp Ser Asp Glu Leu Ala Ala Leu Arg Ala Glu 1 5 10 15 Asn Ala Arg Leu Val Ser Leu Leu Glu Ala His Gly Ile Glu Trp Arg 20 25 30 Arg Lys Pro Gln Thr Pro Val Gln Arg Val Ser Val Leu Ser Thr Asp 35 40 45 Glu Lys Val Ala Leu Phe Arg Arg Leu Phe Arg Gly Arg Asp Asp Val 50 55 60 Trp Ala Leu Arg Trp Glu Ser Lys Thr Ser Gly Lys Ser Gly Tyr Ser 65 70 75 80 Pro Ala Cys Ala Asn Glu Trp Gln Ala Arg Ile Cys Gly Lys Pro Arg 85 90 95 Ile Lys Cys Gly Asp Cys Ala His Arg Gln Leu Ile Pro Val Ser Asp 100 105 110 Leu Val Ile Tyr His His Leu Ala Gly Thr His Thr Val Gly Met Tyr 115 120 125 Pro Leu Leu Glu Asp Asp Ser Cys Tyr Phe Leu Ala Val Asp Phe Asp 130 135 140 Glu Ala Glu Trp Gln Lys Asp Ala Ser Ala Phe Met Arg Ser Cys Asp 145 150 155 160 Glu Leu Gly Val Pro Ala Ala Leu Glu Ile Ser Arg Ser Arg Gln Gly 165 170 175 Ala His Val Trp Ile Phe Phe Ala Ser Arg Val Ser Ala Arg Glu Ala 180 185 190 Arg Arg Leu Gly Thr Ala Ile Ile Ser Tyr Thr Cys Ser Arg Thr Arg 195 200 205 Gln Leu Arg Leu Gly Ser Tyr Asp Arg Leu Phe Pro Asn Gln Asp Thr 210 215 220 Met Pro Lys Gly Gly Phe Gly Asn Leu Ile Ala Leu Pro Leu Gln Lys 225 230 235 240 Arg Pro Arg Glu Leu Gly Gly Ser Val Phe Val Asp Met Asn Leu Gln 245 250 255 Pro Tyr Pro Asp Gln Trp Ala Phe Leu Val Ser Val Thr Pro Met Asn 260 265 270 Val Gln Asp Ile Glu Pro Thr Ile Leu Arg Ala Thr Gly Ser Ile His 275 280 285 Pro Leu Asp Val Asn Phe Ile Asn Glu Glu Asp Leu Gly Thr Pro Trp 290 295 300 Glu Glu Lys Lys Ser Ser Gly Asn Arg Leu Asn Ile Ser Ile Ala Glu 305 310 315 320 Pro Leu Lys Ile Thr Leu Ala Asn Gln Ile Tyr Phe Glu Lys Ala Gln 325 330 335 Leu Pro Gln Val Leu Ile Asn Arg Leu Ile Arg Leu Ala Ala Phe Pro 340 345 350 Asn Pro Glu Phe Tyr Lys Ala Gln Ala Met Arg Met Ser Val Trp Asn 355 360 365 Lys Pro Arg Val Ile Gly Cys Ala Glu Asn Tyr Pro Gln His Ile Ala 370 375 380 Leu Pro Arg Gly Cys Leu Asp Ser Val Leu Ser Phe Leu Arg Asp Asn 385 390 395 400 Asn Ile Ala Ala Glu Leu Ile Asp Lys Arg Phe Ala Gly Thr Glu Cys 405 410 415 Asn Ala Val Phe Met Gly Asn Leu Arg Ala Glu Gln Glu Glu Ala Val 420 425 430 Ser Ala Leu Leu Arg Tyr Asp Thr Gly Val Leu Cys Ala Pro Thr Ala 435 440 445 Phe Gly Lys Thr Val Thr Ala Ala Ala Val Ile Ala Lys Arg Lys Val 450 455 460 Asn Thr Leu Ile Leu Val His Arg Thr Glu Leu Leu Lys Gln Trp Gln 465 470 475 480 Glu Arg Leu Ala Val Phe Leu Gln Ala Gly Asp Ser Ile Gly Ile Ile 485 490 495 Gly Gly Gly Lys His Lys Pro Cys Gly Asn Ile Asp Ile Ala Val Val 500 505 510 Gln Ser Ile Ser Arg Gln Gly Glu Val Glu Pro Leu Val Arg Asn Tyr 515 520 525 Gly Gln Ile Ile Val Asp Glu Cys His His Ile Gly Ala Val Ser Phe 530 535 540 Ser Ala Ile Leu Lys Glu Thr Asn Ala Arg Tyr Leu Leu Gly Leu Thr 545 550 555 560 Ala Thr Pro Ile Arg Arg Asp Gly Leu His Pro Ile Ile Phe Met Tyr 565 570 575 Cys Gly Ala Ile Arg His Thr Ala Val Arg Pro Lys Glu Ser Pro His 580 585 590 Asn Leu Glu Val Leu Ile Arg Ser Arg Phe Thr Ser Gly His Leu Pro 595 600 605 Ser Asp Ala Arg Ile Gln Asp Ile Phe Arg Glu Ile Ala Leu Asp His 610 615 620 Asp Arg Thr Val Ala Ile Ala Glu Glu Ala Met Lys Ala Phe Gly Gln 625 630 635 640 Gly Arg Lys Val Leu Val Leu Thr Glu Arg Thr Asp His Leu Asp Glu 645 650 655 Ile Ala Ser Val Met Asn Ser Leu Lys Leu Ser Pro Phe Ile Leu His 660 665 670 Gly Arg Leu Ser Lys Lys Lys Arg Ala Met Leu Ile Ser Gly Leu Asn 675 680 685 Ala Leu Pro Pro Asp Ser Pro Arg Ile Leu Leu Ser Thr Gly Arg Leu 690 695 700 Ile Gly Glu Gly Phe Asp His Pro Pro Leu Asp Thr Leu Ile Leu Ala 705 710 715 720 Met Pro Val Ser Trp Lys Gly Thr Leu Gln Gln Tyr Ala Gly Arg Leu 725 730 735 His Arg Glu His Thr Gly Lys Ser Asp Val Arg Ile Ile Asp Phe Val 740 745 750 Asp Thr Ala Tyr Pro Val Leu Leu Arg Met Trp Asp Lys Arg Gln Arg 755 760 765 Gly Tyr Lys Ala Met Gly Tyr Arg Ile Ile Ala Asp Gly Asp Glu Ser 770 775 780 Val Ile * 785 <210> 140 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10985..11137) <400> 140 Leu His Asn Gln Phe Pro Glu Ile Gln Pro Trp Phe Val Gly Leu Arg 1 5 10 15 Asn Ser Gln Asn Phe Cys His Thr Val Ile Val Ser Gly Ile Cys Thr 20 25 30 Ala Phe Gly Trp Trp Tyr Gly Asn Lys Cys Val Phe Leu Lys Ile Thr 35 40 45 Asp Ile * 50 <210> 141 <211> 513 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11472..13010) <400> 141 Met Asn Asp Ile Ser Ser Asp Asp Ile Phe Leu Leu Lys Gln Arg Leu 1 5 10 15 Ala Glu Gln Glu Ala Leu Ile His Ala Leu Gln Glu Lys Leu Ser Asn 20 25 30 Arg Glu Arg Glu Ile Asp His Leu Gln Ala Gln Leu Asp Lys Leu Arg 35 40 45 Arg Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala 50 55 60 Gln Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu 65 70 75 80 Thr Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr 85 90 95 Arg Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg 100 105 110 Leu Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser 115 120 125 Tyr Leu Gly Glu Asp Thr Ala Glu Gln Leu Glu Leu Met Arg Ser Ala 130 135 140 Phe Arg Val Ile Arg Thr Val Arg Glu Lys His Ala Cys Thr Gln Cys 145 150 155 160 Asp Ala Ile Val Gln Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly 165 170 175 Ile Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Ser Lys Tyr Ala 180 185 190 Glu His Thr Pro Leu Tyr Arg Gln Ser Glu Ile Tyr Gly Arg Gln Gly 195 200 205 Val Glu Leu Arg Arg Ser Leu Leu Ser Gly Trp Val Asp Ala Cys Cys 210 215 220 Arg Leu Leu Ser Pro Leu Glu Glu Ala Leu His Gly Tyr Val Met Thr 225 230 235 240 Asp Gly Lys Leu His Ala Asp Asp Thr Pro Val Gln Val Leu Leu Pro 245 250 255 Gly Asn Lys Lys Thr Lys Thr Gly Arg Leu Trp Ala Tyr Val Arg Asp 260 265 270 Asp Arg Asn Ala Gly Ser Ala Leu Ala Pro Ala Val Trp Phe Ala Tyr 275 280 285 Ser Pro Asp Arg Lys Gly Ile His Pro Gln Thr His Leu Ala Cys Phe 290 295 300 Ser Gly Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr 305 310 315 320 Arg Asn Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg 325 330 335 Lys Ile His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu 340 345 350 Ala Leu Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg 355 360 365 Gly Met Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys 370 375 380 Pro Leu Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr 385 390 395 400 Leu Ser Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn 405 410 415 Gln Trp Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile 420 425 430 Asp Asn Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg 435 440 445 Lys Asn Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala 450 455 460 Leu Leu Tyr Ser Leu Ile Gly Thr Cys Lys Leu Asn Asp Val Asp Pro 465 470 475 480 Glu Ser Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val 485 490 495 Asn Arg Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu 500 505 510 * <210> 142 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13060..13407) <400> 142 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Asp Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 143 <211> 134 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13404..13805) <400> 143 Val Gly Thr Lys Val Ser Asp Met Gln Lys Asn Val Thr Pro Gly Arg 1 5 10 15 Arg Lys Gly Cys Pro Asn Tyr Pro Pro Glu Phe Lys Gln Gln Leu Val 20 25 30 Ala Ala Ser Cys Glu Pro Gly Ile Ser Ile Ser Lys Leu Ala Leu Glu 35 40 45 Asn Gly Ile Asn Ala Asn Leu Leu Phe Lys Trp Arg Gln Gln Trp Arg 50 55 60 Glu Gly Lys Leu Leu Leu Pro Ser Ser Glu Ser Pro Gln Leu Leu Pro 65 70 75 80 Val Thr Leu Asp Ala Ala Ala Glu Gln Pro Glu Ser Leu Ala Glu Asp 85 90 95 Pro Glu Pro Leu Ser Ile Ser Cys Glu Val Thr Phe Arg His Gly Thr 100 105 110 Leu Arg Phe Asn Gly Asn Val Ser Glu Lys Leu Leu Thr Leu Leu Ile 115 120 125 Gln Glu Leu Lys Arg * 130 <210> 144 <211> 104 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13860..14171) <400> 144 Met Arg Arg Thr Phe Thr Ala Glu Glu Lys Ala Ser Val Phe Glu Leu 1 5 10 15 Trp Lys Asn Gly Thr Gly Phe Ser Glu Ile Ala Asn Ile Leu Gly Ser 20 25 30 Lys Pro Gly Thr Ile Phe Thr Met Leu Arg Asp Thr Gly Gly Ile Lys 35 40 45 Pro His Glu Arg Lys Arg Ala Val Ala His Leu Thr Leu Ser Glu Arg 50 55 60 Glu Glu Ile Arg Ala Gly Leu Ser Ala Lys Met Ser Ile Arg Ala Ile 65 70 75 80 Ala Thr Ala Leu Asn Arg Ser Pro Ser Thr Ile Ser Arg Glu Val Gln 85 90 95 Arg Asn Arg Lys Arg Thr Ala * 100 <210> 145 <211> 273 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14311..15129) <400> 145 Met Cys Gln Val Phe Gly Val Ser Arg Ser Gly Tyr Tyr Asn Trp Val 1 5 10 15 Gln His Glu Pro Ser Asp Arg Lys Gln Ser Asp Glu Arg Leu Lys Leu 20 25 30 Glu Ile Lys Val Ala His Ile Arg Thr Arg Glu Thr Tyr Gly Thr Arg 35 40 45 Arg Leu Gln Thr Glu Leu Ala Glu Asn Gly Ile Ile Val Gly Arg Asp 50 55 60 Arg Leu Ala Arg Leu Arg Lys Glu Leu Arg Leu Arg Cys Lys Gln Lys 65 70 75 80 Arg Lys Phe Arg Ala Thr Thr Asn Ser Asn His Asn Leu Pro Val Ala 85 90 95 Pro Asn Leu Leu Asn Gln Thr Phe Ala Pro Thr Ala Pro Asn Gln Val 100 105 110 Trp Val Ala Asp Leu Thr Tyr Val Ala Thr Gln Glu Gly Trp Leu Tyr 115 120 125 Leu Ala Gly Ile Lys Asp Val Tyr Thr Cys Glu Ile Val Gly Tyr Ala 130 135 140 Met Gly Glu Arg Met Thr Lys Glu Leu Thr Gly Lys Ala Leu Phe Met 145 150 155 160 Ala Leu Arg Ser Gln Arg Pro Pro Ala Gly Leu Ile His His Ser Asp 165 170 175 Arg Gly Ser Gln Tyr Cys Ala Tyr Asp Tyr Arg Val Ile Gln Glu Gln 180 185 190 Phe Gly Leu Lys Thr Ser Met Ser Arg Lys Gly Asn Cys Tyr Asp Asn 195 200 205 Ala Pro Met Glu Ser Phe Trp Gly Thr Leu Lys Asn Glu Ser Leu Ser 210 215 220 His Tyr Arg Phe Lys Ser Arg Asp Glu Ala Ile Ser Val Ile Arg Glu 225 230 235 240 Tyr Ile Glu Ile Phe Tyr Asn Arg Gln Arg Arg His Ser Arg Leu Gly 245 250 255 Asn Ile Ser Pro Ala Ala Phe Arg Glu Lys Tyr His Gln Met Ala Ala 260 265 270 * <210> 146 <211> 249 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15035..15781) <400> 146 Leu Arg Phe Ser Thr Ile Val Ser Val Val Thr Leu Val Trp Gly Ile 1 5 10 15 Ser Pro Arg Gln Pro Ser Gly Lys Asn Ile Ile Arg Trp Leu Leu Lys 20 25 30 Lys Arg Thr Asn Gly Ser Val Arg Tyr Cys Gln Tyr Thr Ser Thr Ile 35 40 45 Trp Leu Glu Pro Ala Ser Glu Arg Thr Val Phe Leu Gln Ile Lys Asn 50 55 60 Thr Ser Asp Lys Asp Met Ser Gly Leu Gln Gly Lys Ile Ala Asp Ala 65 70 75 80 Val Lys Ala Arg Gly Tyr Gln Ile Met Thr Ser Pro Asp Lys Ala Tyr 85 90 95 Tyr Trp Ile Gln Ala Asn Val Leu Lys Ala Asp Lys Met Asp Leu Arg 100 105 110 Glu Ser Gln Gly Trp Leu Ser Arg Gly Tyr Glu Gly Ala Ala Val Gly 115 120 125 Ala Ala Leu Gly Gly Gly Ile Thr Ala Tyr Asn Thr Gly Ser Ala Gly 130 135 140 Thr Thr Leu Gly Val Gly Leu Ala Thr Gly Leu Ile Gly Met Ala Ala 145 150 155 160 Asp Ala Met Val Glu Asp Ile Asn Tyr Thr Met Ile Thr Asp Val Gln 165 170 175 Ile Ala Glu Arg Thr Arg Thr Ser Val Arg Thr Asp Asn Val Ala Ala 180 185 190 Leu Arg Gln Gly Thr Ser Gly Ser Lys Ile Gln Thr Ser Thr Glu Thr 195 200 205 Gly Asn Gln His Lys Tyr Gln Thr Arg Val Val Ser Ser Ala Asn Gln 210 215 220 Val Asn Leu Lys Phe Glu Glu Ala Lys Pro His Leu Glu Asp Gln Leu 225 230 235 240 Ala Lys Ser Ile Ala Asn Ile Leu * 245 <210> 147 <211> 84 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15829..16080) <400> 147 Met Glu Ser Phe Val Gln Asp Ser Pro Phe Tyr Ser Gly Arg Asp Leu 1 5 10 15 Tyr Trp Leu Arg Pro Lys Val Glu Leu Thr Leu Glu Glu Lys Leu Tyr 20 25 30 Tyr Cys Ser Cys Ile Arg Arg Asn Arg His Lys Tyr Ser Tyr Gly Arg 35 40 45 Gln Ala Asn Arg Thr Leu Lys Asn Leu Leu Val Pro Ser Leu Asp Ser 50 55 60 Val Pro Ala Trp Val Tyr Gly Val Thr Gly Lys Ile Ile Ser Glu Leu 65 70 75 80 Ser Glu Arg * <210> 148 <211> 97 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16104..16394) <400> 148 Met Asn Leu Ser Ala Ser Met Asn Asp Ala Gly Asp Gly Phe Glu Leu 1 5 10 15 Leu Met Ser Gly Asn Met Gln Asp Phe Asn Ile Cys Cys Arg Arg Asp 20 25 30 Asn His Tyr Pro Glu His Lys Leu Ile Pro Leu Ser Glu Leu Phe Asp 35 40 45 Val Asn Tyr Gly Leu Asn Leu Glu Leu Asn Lys Leu Glu Lys Asp Ser 50 55 60 Ser Gly Ile Asn Phe Val Ser Arg Thr Ser Lys Asn Asn Gly Val Ser 65 70 75 80 Ala Arg Val Lys Leu Lys Asp Gly Ile Ser Pro Cys Gln Gln Leu Cys 85 90 95 * <210> 149 <211> 67 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16470..16670) <400> 149 Met Ile Asp Ala Asp Leu Ser Arg Tyr Ala Gln Gln Leu Trp Ile Gln 1 5 10 15 Gly Ile Phe Ser Ala Arg Tyr Ser Tyr Gln Ile Asp Asp Leu Phe Ala 20 25 30 Gln Met Leu Phe Val Leu Ser Gln Pro Gly Phe Cys Gly His Ile His 35 40 45 Cys Ser Pro Met Gly Asn Arg Asp Arg Arg Leu Ala Val Met Arg Phe 50 55 60 Cys Arg * 65 <210> 150 <211> 120 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17080..17439) <400> 150 Met Ala Asn Thr Thr Thr Gly Val Thr Arg Ile Ile Lys Ala Ala Gly 1 5 10 15 Tyr Ser Trp Lys Gly Leu Cys Ala Ala Trp Arg Tyr Glu Ala Ala Phe 20 25 30 Arg Gln Glu Cys Ile Leu Val Leu Ser Ala Leu Ile Ile Ser Phe Trp 35 40 45 Leu Asp Val Asp Ser Val Thr Arg Val Leu Leu Ile Gly Ser Ala Met 50 55 60 Met Val Ile Ile Val Glu Ile Ile Asn Ser Ala Ile Glu Ala Val Val 65 70 75 80 Asp Arg Ile Gly Ser Glu His His Glu Leu Ser Gly Arg Ala Lys Asp 85 90 95 Met Gly Ser Ala Ala Val Leu Ile Thr Ile Leu Val Ala Ile Ile Ile 100 105 110 Trp Gly Val Leu Leu Leu Ser * 115 <210> 151 <211> 429 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17532..18818) <400> 151 Met Thr Ser Tyr Phe Asn Met Ser Val Val Leu Trp Phe Leu Phe Thr 1 5 10 15 Gly Ile Leu Pro Cys Gly Leu Leu Leu Leu Val Asn Ile Arg Tyr Pro 20 25 30 Glu Thr Trp Ile Lys Gly Ile Thr Tyr Arg Leu Ile Ser Met Phe Ala 35 40 45 Ser Leu Leu Ile Ile Phe Ala Ile Ala Phe Phe Phe Tyr Lys Asp Tyr 50 55 60 Ala Ser Val Gly Arg Asn Asn Ser Ser Leu Asn Lys Glu Ile Ile Pro 65 70 75 80 Thr Asn Tyr Ile Tyr Ser Gly Phe Lys Tyr Val Arg Asp Phe Phe Val 85 90 95 Ser Pro Gly Glu Phe Arg Gln Thr Gly Thr Asp Ala Ser Arg Thr Ile 100 105 110 Asn Glu Lys Gln Lys Pro Val Ile Met Phe Leu Val Val Gly Glu Thr 115 120 125 Ala Arg Ser Gln Asn Tyr Ala Leu Asn Gly Tyr Ser Arg Gly Thr Asn 130 135 140 Asp Phe Thr Lys Lys Tyr Asn Glu Leu Ile Ser Phe His Asn Val Gln 145 150 155 160 Ser Cys Gly Thr Ser Thr Ala Ile Ser Val Pro Cys Met Phe Ser Asp 165 170 175 Met Lys Arg Lys Glu Phe Asn Ser Arg Lys Ala Val Asn Ser Glu Asn 180 185 190 Val Leu Asp Ile Leu Tyr Arg Thr Gly Val Asn Leu Leu Trp Ile Glu 195 200 205 Asn Asp Gly Gly Cys Lys Gly Val Cys Lys Arg Ile Pro Thr Ile Asn 210 215 220 Ile Glu Pro Ser Asn Ser Asp Asn Thr Leu Cys Lys Lys Asn Ser Cys 225 230 235 240 Tyr Asp Glu Val Met Leu Lys Asn Ile Asp Glu Tyr Ile Asn Asn Asn 245 250 255 Ser Glu Asp Lys Leu Ile Val Phe His Leu Met Gly Ser His Gly Pro 260 265 270 Thr Tyr Tyr Leu Arg Tyr Pro Glu Ser His Lys Tyr Phe Lys Pro Thr 275 280 285 Cys Asp Arg Ser Asp Ile Glu Asn Cys Thr His Glu Gln Leu Ile Asn 290 295 300 Thr Tyr Asp Asn Thr Ile Arg Tyr Thr Asp Tyr Ile Ile Ser Lys Leu 305 310 315 320 Ile Asp Lys Leu Ile Glu Tyr Lys Asp Glu Tyr Asp Thr Val Leu Leu 325 330 335 Tyr Val Ser Asp His Gly Glu Ser Leu Gly Glu Asn Gly Leu Tyr Leu 340 345 350 His Gly Thr Pro Tyr Asn Val Ala Pro Ala Glu Gln Thr His Val Pro 355 360 365 Leu Ile Thr Trp Met Ser Pro Gly Phe Val Ser Ser Lys Lys Ile Asp 370 375 380 Leu Asn Cys Leu Ser Glu His Ala Leu Asn Arg Thr Val Ser His Asp 385 390 395 400 Asn Ile Phe Ser Ser Leu Leu Gly Leu Trp Asn Val Asn Thr Ser Val 405 410 415 Tyr Asn Lys Glu Asp Asp Ile Ile Ser Ser Cys Arg * 420 425 <210> 152 <211> 48 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19078..19221) <400> 152 Leu Asn Asn Val Ala Lys Thr Thr Ser Ile Ile Asn Ile Lys Lys Arg 1 5 10 15 Lys Leu Ile Leu Ile Phe Leu Ile Ile Leu Pro Pro Leu Ile Arg Ala 20 25 30 Tyr Asn Cys Pro Tyr Leu Lys Val Ile Tyr Phe Tyr Lys Thr Trp * 35 40 45 <210> 153 <211> 92 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19376..19651) <400> 153 Met Thr Glu His Trp Ser Gly His Ala Asp Asp Asn Phe Pro Phe Ser 1 5 10 15 Trp Gly Ser Asp Ser Ile Phe Met His Ala Cys Leu Gln Ser Tyr Gly 20 25 30 Glu Ser Ile Cys Asp Thr Val His Thr Phe Val Ala Asp Val Ala Pro 35 40 45 Glu Ser Leu Thr Gly Leu Gln Thr Val Tyr Leu Tyr Thr Ala Gly Leu 50 55 60 Leu Cys Asp Ile Val Phe His Ile Glu Gly Gly Pro Pro Glu Met Asn 65 70 75 80 Gly Ile Ile Ile Phe Pro Asp Asp Ile Ile Pro * 85 90 <210> 154 <211> 68 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19703..19906) <400> 154 Val Ser Phe Arg Leu Asn Asn Thr Asn Val Cys Phe Arg His Glu Ala 1 5 10 15 Phe Arg Leu Pro Gly Leu Tyr Ile Ala Arg Lys Ala Met His Ile Val 20 25 30 Gly Ile Ile Gln Arg Ile Arg Gln Lys Asp Pro Thr Met Gly Cys Asp 35 40 45 Tyr Ala Ile Trp Leu Arg Met Ile Ser Arg Cys Tyr Gly Asp Asn Leu 50 55 60 Leu Ile Gln * 65 <210> 155 <211> 248 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19987..20730) <400> 155 Leu Leu Ser Thr Ala Leu Pro Gln Asn Lys Lys Gly Trp Gln Ala Met 1 5 10 15 Leu Asp Leu Arg Phe Gln Arg Leu His Gly Lys Thr Thr Leu Thr Thr 20 25 30 Arg His His Val Gly Leu Leu Thr Val Gln Arg Pro Phe Tyr Pro Glu 35 40 45 Glu Glu Thr Cys His Leu Cys Leu Leu His Pro Pro Gly Gly Ile Val 50 55 60 Gly Gly Asp Glu Leu Ile Ile Asn Ala Ile Ile Asp Ser Asp Cys His 65 70 75 80 Thr Leu Ile Thr Met Pro Gly Ala Ser Lys Phe Tyr Arg Ser Ser Gly 85 90 95 Ala Gln Ala His Leu Gln Gln Asn Leu Thr Leu Cys Asn Asn Ala Thr 100 105 110 Leu Glu Trp Leu Pro Gln Asp Ser Ile Phe Phe Pro Gly Ala His Ala 115 120 125 Thr Leu His Thr Val Phe His Leu Ser Ser Ser Ser Thr Leu Leu Ala 130 135 140 Trp Asp Leu Leu Cys Leu Gly Arg Pro Val Ile Gly Glu Thr Phe Ser 145 150 155 160 His Gly Thr Leu Ala Asn Arg Leu Glu Ile Trp Val Asp Gly Ser Pro 165 170 175 Leu Leu Ile Glu Arg Leu His Val Ala Asn Gly Glu Leu Thr Cys Val 180 185 190 Ala Arg Lys Pro Trp Val Gly Thr Met Leu Phe Tyr Leu Gly Asn Glu 195 200 205 Thr Gln Leu Glu Asp Ile Arg Glu Lys Leu Thr Pro Leu Glu Asn Tyr 210 215 220 Ala Gly Ala Thr Leu Thr Asp Gly Leu Leu Thr Val Arg Phe Leu Ser 225 230 235 240 Asp Asp Asn Leu Arg Cys Gln * 245 <210> 156 <211> 101 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20821..21123) <400> 156 Met Glu Leu Thr Pro Arg Glu Lys Asp Lys Leu Leu Leu Phe Thr Ala 1 5 10 15 Ala Leu Leu Ala Glu Arg Arg Leu Ala Arg Gly Leu Lys Leu Asn Tyr 20 25 30 Pro Glu Ser Val Ala Leu Ile Ser Ala Phe Ile Met Glu Gly Ala Arg 35 40 45 Asp Gly Lys Ser Val Ala Ala Leu Met Glu Glu Gly Arg His Val Leu 50 55 60 Ser Arg Glu Gln Val Met Glu Gly Ile Pro Glu Met Ile Pro Asp Ile 65 70 75 80 Gln Val Glu Ala Thr Phe Pro Asp Gly Ser Lys Leu Val Thr Val His 85 90 95 Asn Pro Ile Ile * 100 <210> 157 <211> 107 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21132..21452) <400> 157 Met Ile Pro Gly Glu Tyr Lys Val Lys Pro Gly Tyr Ile Glu Leu Asn 1 5 10 15 Ile Gly Arg Ala Thr Cys Ser Ile Ile Val Glu Asn His Gly Asp Arg 20 25 30 Pro Ile Gln Val Gly Ser His Tyr His Phe Ala Glu Val Asn Pro Ala 35 40 45 Leu Lys Phe Asp Arg Gln Lys Ala Arg Gly Tyr Arg Leu Asn Ile Ala 50 55 60 Ala Gly Thr Ala Val Arg Phe Glu Pro Gly Gln Lys Arg Glu Val Glu 65 70 75 80 Leu Val Ala Leu Ser Gly Ala Arg Ile Val His Gly Phe Arg Gly Asp 85 90 95 Ile Met Gly Glu Leu Glu Ala Asn Asp Glu * 100 105 <210> 158 <211> 569 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21442..23148) <400> 158 Met Met Ser Asn Ile Ser Arg Gln Ala Tyr Ala Asp Met Phe Gly Pro 1 5 10 15 Thr Thr Gly Asp Lys Ile Arg Leu Ala Asp Thr Glu Leu Trp Ile Glu 20 25 30 Val Glu Asp Asp Leu Thr Thr Tyr Gly Glu Glu Val Lys Phe Gly Gly 35 40 45 Gly Lys Val Ile Arg Asp Gly Met Gly Gln Gly Gln Met Leu Ser Ala 50 55 60 Gly Cys Ala Asp Leu Val Leu Thr Asn Ala Leu Ile Ile Asp Tyr Trp 65 70 75 80 Gly Ile Val Lys Ala Asp Ile Gly Val Lys Asp Gly Arg Ile Phe Ala 85 90 95 Ile Gly Lys Ala Gly Asn Pro Asp Ile Gln Pro Asn Val Thr Ile Pro 100 105 110 Ile Gly Val Ser Thr Glu Ile Ile Ala Ala Glu Gly Arg Ile Val Thr 115 120 125 Ala Gly Gly Val Asp Thr His Ile His Trp Ile Cys Pro Gln Gln Ala 130 135 140 Glu Glu Ala Leu Thr Ser Gly Ile Thr Thr Met Ile Gly Gly Gly Thr 145 150 155 160 Gly Pro Thr Ala Gly Ser Asn Ala Thr Thr Cys Thr Pro Gly Pro Trp 165 170 175 Tyr Ile Tyr Gln Met Leu Gln Ala Ala Asp Ser Leu Pro Val Asn Ile 180 185 190 Gly Leu Leu Gly Lys Gly Asn Cys Ser Asn Pro Asp Ala Leu Arg Glu 195 200 205 Gln Val Ala Ala Gly Val Ile Gly Leu Lys Ile His Glu Asp Trp Gly 210 215 220 Ala Thr Pro Ala Val Ile Asn Cys Ala Leu Thr Val Ala Asp Glu Met 225 230 235 240 Asp Val Gln Val Ala Leu His Ser Asp Thr Leu Asn Glu Ser Gly Phe 245 250 255 Val Glu Asp Thr Leu Thr Ala Ile Gly Gly Arg Thr Ile His Thr Phe 260 265 270 His Thr Glu Gly Ala Gly Gly Gly His Ala Pro Asp Ile Ile Thr Ala 275 280 285 Cys Ala His Pro Asn Ile Leu Pro Ser Ser Thr Asn Pro Thr Leu Pro 290 295 300 Tyr Thr Val Asn Thr Ile Asp Glu His Leu Asp Met Leu Met Val Cys 305 310 315 320 His His Leu Asp Pro Asp Ile Ala Glu Asp Val Ala Phe Ala Glu Ser 325 330 335 Arg Ile Arg Gln Glu Thr Ile Ala Ala Glu Asp Val Leu His Asp Leu 340 345 350 Gly Ala Phe Ser Leu Thr Ser Ser Asp Ser Gln Ala Met Gly Arg Val 355 360 365 Gly Glu Val Val Leu Arg Thr Trp Gln Val Ala His Arg Met Lys Val 370 375 380 Gln Arg Gly Pro Leu Pro Glu Glu Ser Gly Asp Asn Asp Asn Val Arg 385 390 395 400 Val Lys Arg Tyr Ile Ala Lys Tyr Thr Ile Asn Pro Ala Leu Thr His 405 410 415 Gly Ile Ala His Glu Val Gly Ser Ile Glu Val Gly Lys Leu Ala Asp 420 425 430 Leu Val Leu Trp Ser Pro Ala Phe Phe Gly Val Lys Pro Ala Thr Ile 435 440 445 Val Lys Gly Gly Met Ile Ala Met Ala Pro Met Gly Asp Ile Asn Gly 450 455 460 Ser Ile Pro Thr Pro Gln Pro Val His Tyr Arg Pro Met Phe Ala Ala 465 470 475 480 Leu Gly Ser Ala Arg His Arg Cys Arg Val Thr Phe Leu Ser Gln Ala 485 490 495 Ala Ala Ala Asn Gly Val Ala Glu Gln Leu Asn Leu His Ser Thr Thr 500 505 510 Ala Val Val Lys Gly Cys Arg Thr Val Gln Lys Ala Asp Met Arg His 515 520 525 Asn Ser Leu Leu Pro Asp Ile Thr Val Asp Ser Gln Thr Tyr Glu Val 530 535 540 Arg Ile Asn Gly Glu Leu Ile Thr Ser Glu Pro Ala Asp Ile Leu Pro 545 550 555 560 Met Ala Gln Arg Tyr Phe Leu Phe * 565 <210> 159 <211> 155 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23158..23622) <400> 159 Met Leu Tyr Leu Thr Arg Arg Val Glu Thr Pro Ala Gln Thr Thr Ala 1 5 10 15 Ser Val Thr Leu Pro Val Asp Met Arg Val Lys Ser Arg Ile Lys Val 20 25 30 Thr Leu Asn Asp Gly Arg Gln Ala Gly Leu Leu Leu Pro Arg Gly Leu 35 40 45 Leu Leu Arg Asp Gly Asp Ile Leu Ser Asn Glu Asn Gly Asp Glu Phe 50 55 60 Ile Lys Val Ile Ala Ala Asp Glu Ala Val Ser Val Val Arg Cys Ala 65 70 75 80 Asp Pro Phe Met Leu Ala Lys Ala Cys Trp His Leu Gly Asn Arg His 85 90 95 Val Pro Leu Gln Ile Met Pro Gly Glu Leu Arg Tyr His His Asp His 100 105 110 Val Leu Asp Asp Met Leu Arg Gln Phe Gly Leu Asp Val Asp Phe Ala 115 120 125 His Leu Pro Phe Glu Pro Glu Ala Gly Ala Tyr Ala Ser Lys Ser His 130 135 140 Ala His Asn His Asp Gln Glu His Ser His * 145 150 <210> 160 <211> 225 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23623..24297) <400> 160 Met Pro Thr Pro Glu Lys Arg Leu Arg Leu Met Gln Leu Ala Ser Asn 1 5 10 15 Ser Leu Pro Val Gly Gly Tyr Ser Trp Ser Gln Gly Leu Glu Trp Ala 20 25 30 Val Glu Ala Gly Trp Val Glu Asp Ser Ala Ala Phe Glu His Trp Gln 35 40 45 Gln Leu Gln Met Glu Gln Ser Phe Phe Ala Val Asp Leu Pro Leu Leu 50 55 60 Ala Arg Leu Tyr Arg Ala Cys Glu Ala Gly Asp Pro Asp Ser Ala Gly 65 70 75 80 Arg Trp Thr Ala Tyr Leu Leu Ala Cys Arg Glu Thr Arg Glu Leu Arg 85 90 95 Asp Glu Glu Arg Asn Arg Gly Ala Ala Phe Thr Arg Leu Leu Val Asp 100 105 110 Trp Gln Pro Asp Cys Pro Ala Glu Trp Arg Lys Leu Cys Gln Gln Ser 115 120 125 Gln Leu Thr Gly Met Ala Trp Leu Gly Val Arg Trp Gln Ile Ser Val 130 135 140 Ser Asp Leu Ala Leu Ser Leu Gly Tyr Ser Trp Ile Glu Ser Ala Val 145 150 155 160 Met Ala Gly Val Arg Leu Val Pro Tyr Gly Gln Leu Ala Ala Gln Gln 165 170 175 Leu Ile Met Arg Leu Cys Ala Arg Tyr Ala Ala Asn Met Asp Ser Ala 180 185 190 Leu Ala Thr Pro Asp His Ala Ile Gly Ser Ala Thr Pro Leu Ala Ser 195 200 205 Ile Ala Ser Ala Arg His Glu Thr Gln Tyr Ser Arg Leu Phe Arg Ser 210 215 220 * <210> 161 <211> 206 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24309..24926) <400> 161 Met Asn Ile Ile Lys Gln Pro Leu Arg Val Gly Val Gly Gly Pro Val 1 5 10 15 Gly Ser Gly Lys Thr Ala Leu Leu Glu Ala Leu Cys Lys Ser Met Arg 20 25 30 Asp Thr Trp Gln Leu Ala Val Val Thr Asn Asp Ile Tyr Thr Arg Glu 35 40 45 Asp Gln Arg Ile Leu Thr Glu Ala Gly Ala Leu Glu Ala Glu Arg Ile 50 55 60 Val Gly Val Glu Thr Gly Gly Cys Pro His Thr Ala Ile Arg Glu Asp 65 70 75 80 Ala Ser Met Asn Leu Ala Ala Val Glu Ala Leu Ser Glu Lys Phe Gly 85 90 95 Asn Leu Glu Leu Ile Phe Val Glu Ser Gly Gly Asp Asn Leu Ser Ala 100 105 110 Thr Phe Ser Pro Glu Leu Ala Asp Leu Thr Ile Tyr Val Ile Asp Val 115 120 125 Ala Glu Gly Glu Lys Ile Pro Arg Lys Gly Gly Pro Gly Ile Thr Lys 130 135 140 Ser Asp Phe Leu Val Ile Asn Lys Thr Asp Leu Ala Pro Tyr Val Gly 145 150 155 160 Ala Ser Leu Glu Val Met Glu Arg Asp Thr Leu Arg Met Arg Gly Glu 165 170 175 Arg Pro Trp Gly Phe Thr Asn Leu Lys Ser Gly Glu Gly Leu Gln Asn 180 185 190 Ile Ile Ala Phe Ile Glu Glu Gln Gly Met Leu Gly Lys * 195 200 205 <210> 162 <211> 114 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25182..25523) <400> 162 Met Ser Arg Lys Thr Gln Arg Tyr Ser Lys Glu Phe Lys Ala Glu Ala 1 5 10 15 Val Arg Thr Val Leu Glu Asn Gln Leu Ser Ile Ser Glu Gly Ala Ser 20 25 30 Arg Leu Ser Leu Pro Glu Gly Thr Leu Gly Gln Trp Val Thr Ala Ala 35 40 45 Arg Lys Gly Leu Gly Thr Pro Gly Ser Arg Thr Val Ala Glu Leu Glu 50 55 60 Ser Glu Ile Leu Gln Leu Arg Lys Ala Leu Asn Glu Ala Arg Leu Glu 65 70 75 80 Arg Asp Ile Leu Lys Lys Ala Ala Val Asp Ser Ile Cys Gln Cys Asn 85 90 95 Thr Pro Phe Asn Tyr Leu Phe His Cys Pro Arg Arg Tyr Arg Leu Ser 100 105 110 Val * <210> 163 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25562..25717) <400> 163 Val Ser Val Lys Leu Arg Leu Pro Gln Val Ser Leu Ile Trp Val Phe 1 5 10 15 Thr Ser Arg Phe Arg Phe Leu Ile Ala Val Pro Met Ala Pro His Pro 20 25 30 Glu Arg Ala Ser Ala Glu Leu Thr Ser Ala Ile Ile Ile Thr Phe Leu 35 40 45 Val Phe Ile * 50 <210> 164 <211> 88 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26138..26401) <400> 164 Val Lys Pro Asn Ile His Pro Glu Tyr Arg Thr Val Val Phe His Asp 1 5 10 15 Thr Ser Ile Asp Glu Tyr Phe Arg Ile Gly Ser Thr Ile Lys Thr Asp 20 25 30 Arg Val Ile Glu Leu Asp Gly Val Thr Tyr Pro Tyr Val Thr Ile Asp 35 40 45 Val Ser Ser Lys Ser His Pro Phe Tyr Thr Gly Lys Leu Arg Thr Val 50 55 60 Ala Ser Glu Gly Asn Val Ala Arg Phe Thr Gln Arg Phe Gly Arg Phe 65 70 75 80 Val Asp Ala Lys Lys Gly Gly * 85 <210> 165 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26775..27056) <400> 165 Val Lys Phe Leu Thr Glu Ser Ser Ala Pro Phe Tyr Gly Ala Phe Phe 1 5 10 15 Gly Ala Pro Thr Leu Leu Pro His Phe Arg Asp Ala Asn Lys Lys Ala 20 25 30 His Ser Phe Tyr Thr Ala Asp Phe Cys Phe Phe Phe Val Ile Cys Val 35 40 45 Gln Gly Cys Asp Phe Arg Pro Asn Leu Trp Gln Pro Asp Ser Gly Asp 50 55 60 Cys Cys Pro Arg Cys Gly Phe Leu Arg Phe Thr Leu Gln Glu Arg Arg 65 70 75 80 Asn Phe Arg Pro His Glu Ala Tyr Pro Glu Phe Thr Arg * 85 90 <210> 166 <211> 114 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27328..27669) <400> 166 Met Asn Arg Lys Phe Tyr Phe Lys Asn Ile Leu Trp Gly Met Cys Pro 1 5 10 15 Ile Ile Ile Ser Ile Leu His Leu Ile Tyr Asp Thr Pro Thr Glu Ala 20 25 30 Ser Ile Lys Val Asp Leu Phe Leu Ile Leu Ser Gly Leu Ala Leu Pro 35 40 45 Cys Ser Ile Tyr Leu Thr Lys Thr Ile Thr Leu Lys Tyr Thr Ser Ile 50 55 60 Ser Phe Trp Lys Lys Pro Leu Phe Trp Ser Tyr Gly Ile Tyr His Phe 65 70 75 80 His Leu Val Tyr Ile Met Ile Cys Ile Val Leu Ala Ile Pro Ser Ala 85 90 95 Ile Ile Val Leu Phe Phe His Phe Tyr Gln Asn Ile Thr Arg Asn Trp 100 105 110 Lys * <210> 167 <211> 224 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27715..28386) <400> 167 Met Glu Phe Ser Val Ile Phe Phe Trp Val Ile Thr Gly Leu Ile Thr 1 5 10 15 Ile Leu Phe Leu Lys Ser Ile Ile Thr Asp Leu Ile Lys Asn Leu Asn 20 25 30 Lys Thr Asp Ile Ala Leu Tyr Ile Leu Ala Phe Leu Ser Ala Gly Tyr 35 40 45 Thr Phe Gln Tyr Ile Tyr Asn Asp Asn Ile Phe Ser Glu Leu Trp Gly 50 55 60 Val Gly Leu Phe Val Thr Leu Ile Val Leu Asn Ile Val Phe Asn Leu 65 70 75 80 Phe Phe Arg Leu Leu Phe Ile Leu Ser Lys Met Ile Leu Met Ser Arg 85 90 95 His Ile Arg Lys Met Gln Lys Lys Leu Lys Gln Thr Ser Val Pro Asp 100 105 110 Phe Ile Tyr Tyr Ser Ile Glu Lys His Asn Lys Tyr Pro Ile Tyr Val 115 120 125 Leu His Met Pro Ser Asn Asn Ile Ile Glu Ile Gly Tyr Asn Ile Ile 130 135 140 Asn Thr Asp Leu Val Ile Gly Glu Lys Ile His Phe Arg Thr Leu Ser 145 150 155 160 Asn Arg Ser Leu Tyr Phe Asn Leu Thr His Pro Pro Leu Ile Ala Thr 165 170 175 Ile Lys Asp Asp Val Phe Cys Thr Leu His Asp Tyr Tyr Asn His Asn 180 185 190 Asn Glu Thr Lys Ser Thr Ile Asp Asn Tyr Ile Ser Lys Ile Lys Asp 195 200 205 Asn His Asn Thr Pro Trp Leu Leu Asn Asn Glu Asn Val Gln Glu * 210 215 220 <210> 168 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28589..28744) <400> 168 Met Tyr His His Lys Gly Ile Leu Phe Gln Ala Thr Arg Ile Leu Gln 1 5 10 15 Ser Pro Glu Gly Val Ser Leu Arg Leu Leu Lys His Trp Leu Ala Val 20 25 30 Thr Arg Arg Arg Pro Ser Gln Thr Ala Gly Thr Leu Ala Gly Arg Lys 35 40 45 Ser Asp Ser * 50 <210> 169 <211> 254 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29461..30222) <400> 169 Met His Thr Asn Asp Arg Ser Leu Thr Met Val Asp Leu Phe Cys Cys 1 5 10 15 Ala Gly Ala Thr Ala Arg Leu Val Ser Glu Ala Gly Ser Glu Glu Leu 20 25 30 Arg Tyr Cys Ser Gly Glu Leu Ile Leu Thr His Phe Ser Gly Glu Pro 35 40 45 Leu Ala Ala His Thr Ile Asp His Arg Leu Thr Met Val Asp Leu Phe 50 55 60 Cys Cys Thr Gly Ala Thr Ala Arg Leu Val Ser Glu Ala Gly Ser Glu 65 70 75 80 Glu Leu Ser Arg Val Ile Ala Ser Gly Arg Glu Val Leu Thr Arg Val 85 90 95 Leu Met Ala Gly Asp Glu Val Gln Pro Arg Glu Trp Leu Arg Ala Asp 100 105 110 Ser Gly Ser Asp Ser Leu Ser Ala Arg Val Val Ala Ala Leu Ala His 115 120 125 Phe Leu Ser Ser Gly Val Gln Leu Pro Thr Ala Gly Tyr Gly Pro Leu 130 135 140 His Glu His Leu Met Ala Gly Ile Thr His Pro Glu Lys Val Asn Pro 145 150 155 160 Ser Arg Gly Ser Asn Ser Ser Ser Arg Ser Ser Gly His Ser Gly Arg 165 170 175 Arg Val Arg Thr Ser Val Ser Gln Ala Cys Gly Ser Arg Pro Leu Arg 180 185 190 Phe Ala Val Ser Arg Arg Leu Ile Ile Cys Ala Ala Arg Phe Pro Ala 195 200 205 Ile Ser Glu Pro Ala Asn Asn His Ala Phe Arg Pro Met Thr Thr Gly 210 215 220 Arg Ile Ala Arg Ser Gln Ile Leu Leu Ser Arg Gly Thr Ala Pro Ser 225 230 235 240 Leu Arg Lys Gln Leu Ser Ser Ser Arg Arg Phe Arg Ile * 245 250 <210> 170 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29919..30518) <400> 170 Val Tyr Lys Ser Leu Ala Asp Asn Asp Pro Gly Ile Thr Ser Ala Cys 1 5 10 15 Cys Trp Ser His Ala Arg Arg Gly Phe Ala Asn Leu Tyr Lys Ala Ser 20 25 30 Arg Glu Pro Arg Ala Ala Met Ala Leu Arg Lys Ile Ala Gly Leu Tyr 35 40 45 Arg Ile Glu Lys Phe Ile Arg Glu Arg Pro Val Glu Lys Ile Arg Gln 50 55 60 Trp Arg Gln Arg Tyr Ser Arg Pro Ile Val Asn Asp Leu Phe Ala Trp 65 70 75 80 Pro Glu Glu Gln Glu Pro Cys Cys Pro Pro Asp Gly Pro Leu Asn Lys 85 90 95 Ala Ile Asn Tyr Ile Leu Asn Arg Arg Asp Glu Leu Ser Cys Phe Leu 100 105 110 Ser Asp Gly Ala Val Pro Leu Asp Asn Asn Ile Cys Glu Arg Ala Ile 115 120 125 Arg Pro Val Val Met Gly Arg Lys Ala Trp Leu Phe Ala Gly Ser Leu 130 135 140 Met Ala Gly Asn Arg Ala Ala Gln Ile Met Ser Leu Leu Glu Thr Ala 145 150 155 160 Lys Arg Asn Gly Leu Glu Pro His Ala Trp Leu Thr Asp Val Leu Thr 165 170 175 Arg Leu Pro Glu Trp Pro Glu Asp Arg Leu Glu Glu Leu Leu Pro Leu 180 185 190 Glu Gly Phe Thr Phe Ser Gly * 195 <210> 171 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30724..31149) <400> 171 Met Glu Gln Lys Ile Leu Ser Ser Glu Pro Arg Arg Ser Phe Ser Asn 1 5 10 15 Glu Phe Lys Leu Gln Met Val Lys Leu Ala Ser Gln Pro Gly Ala Ser 20 25 30 Val Ala Arg Ile Ala Arg Glu His Asp Ile Asn Asp Asn Leu Leu Phe 35 40 45 Lys Trp Leu Arg Leu Trp Gln Asn Glu Arg Arg Ile Ser Arg Arg Leu 50 55 60 Pro Val Thr Thr Ser Ser Gly Ala Gly Val Glu Leu Leu Pro Val Glu 65 70 75 80 Ile Thr Pro Asp Glu Gln Lys Glu Pro Met Ala Ala Leu Thr Pro Leu 85 90 95 Leu Ser Thr Pro Ser Gln Ser Thr Val Ser Ala Ser Ser Cys Lys Val 100 105 110 Glu Phe Arg His Gly Asn Met Thr Leu Glu Asn Pro Ser Pro Glu Leu 115 120 125 Leu Thr Val Leu Ile Arg Glu Leu Thr Gly Arg Gly Arg * 130 135 140 <210> 172 <211> 117 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31146..31496) <400> 172 Met Ile Ser Leu Pro Ser Gly Thr Arg Ile Trp Leu Val Ala Gly Val 1 5 10 15 Thr Asp Met Arg Lys Ser Phe Asn Gly Leu Gly Glu Gln Val Gln His 20 25 30 Val Leu Asp Glu Asn Pro Phe Ser Gly His Leu Phe Ile Phe Arg Gly 35 40 45 Arg Arg Gly Asp Thr Ile Lys Ile Leu Trp Ala Asp Ala Asp Gly Leu 50 55 60 Cys Leu Phe Thr Lys Arg Leu Glu Glu Gly Gln Phe Ile Trp Pro Ala 65 70 75 80 Val Arg Asp Gly Lys Val Ser Ile Thr Arg Ser Gln Leu Ala Met Leu 85 90 95 Leu Asp Lys Leu Asp Trp Arg Gln Pro Lys Thr Ser Arg Leu Asn Ala 100 105 110 Leu Thr Met Leu * 115 <210> 173 <211> 538 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31527..33140) <400> 173 Met Ser Arg Lys Tyr Leu Ile Arg Ile Thr Glu Leu Glu Arg Leu Leu 1 5 10 15 Ser Glu Gln Ala Glu Ala Leu Arg Gln Lys Asp Gln Gln Leu Ser Leu 20 25 30 Val Glu Glu Thr Glu Ala Phe Leu Arg Ser Ala Leu Ala Arg Ala Glu 35 40 45 Glu Lys Ile Glu Glu Glu Glu Arg Glu Ile Glu His Leu Arg Ala Gln 50 55 60 Ile Glu Lys Leu Arg Arg Met Leu Phe Gly Thr Arg Ser Glu Lys Leu 65 70 75 80 Gln Arg Glu Val Glu Gln Ala Glu Ala Gln Leu Lys Gln Arg Glu Gln 85 90 95 Glu Ser Asp Arg Tyr Ser Gly Arg Glu Asp Asp Pro Gln Val Pro Arg 100 105 110 Gln Leu Arg Gln Ser Arg His Arg Arg Pro Leu Pro Ala His Leu Pro 115 120 125 Arg Glu Ile His Arg Leu Glu Pro Glu Glu Ser Cys Cys Pro Glu Cys 130 135 140 Gly Ser Glu Leu Asp Tyr Leu Gly Glu Val Ser Ala Glu Gln Leu Glu 145 150 155 160 Leu Val Ser Ser Ala Leu Lys Val Ile Arg Thr Val Arg Val Lys Lys 165 170 175 Ala Cys Thr Lys Cys Asp Cys Ile Val Glu Ala Pro Ala Pro Ser Arg 180 185 190 Pro Ile Glu Arg Gly Ile Ala Gly Ser Gly Leu Leu Ala Arg Val Leu 195 200 205 Thr Gly Lys Tyr Cys Glu His Leu Pro Leu Tyr Arg Gln Ser Glu Ile 210 215 220 Phe Ala Arg Gln Gly Ile Glu Leu Ser Arg Ala Leu Leu Ser Asn Trp 225 230 235 240 Val Asp Ala Cys Cys Gln Leu Met Thr Leu Leu Asn Asp Thr Leu Tyr 245 250 255 Arg Tyr Val Met Asn Thr Arg Lys Val His Thr Asp Asp Thr Pro Val 260 265 270 Lys Val Leu Ala Pro Gly Arg Lys Lys Ala Lys Thr Gly Arg Ile Trp 275 280 285 Thr Tyr Val Arg Asp Asp Arg Asn Ala Gly Ser Ser Glu Pro Pro Ala 290 295 300 Val Trp Phe Ala Tyr Ser Pro Asp Arg Gln Gly Lys His Pro Val Gln 305 310 315 320 His Leu Arg Pro Phe Arg Gly Ile Leu Gln Ala Asp Ala Phe Ser Gly 325 330 335 Tyr Asp Arg Leu Phe Ser Ala Glu Arg Glu Gly Gly Ala Leu Thr Glu 340 345 350 Val Ala Cys Trp Ala His Ala Arg Arg Lys Ile His Asp Val Tyr Ile 355 360 365 Ser Ser Lys Ser Ala Thr Ala Glu Glu Ala Leu Lys Arg Ile Ser Glu 370 375 380 Leu Tyr Ala Ile Glu Asp Glu Ile Arg Gly Leu Pro Glu Ser Glu Arg 385 390 395 400 Leu Ala Val Arg Gln Gln Arg Ser Lys Val Leu Leu Thr Ser Leu His 405 410 415 Glu Trp Met Val Glu Lys Asn Gly Thr Leu Ser Lys Lys Ser Arg Leu 420 425 430 Gly Glu Ala Cys Ser Tyr Val Leu Asn Gln Trp Asp Ala Leu Cys Tyr 435 440 445 Tyr Ser Asp Asp Gly Leu Ala Glu Ala Asp Asn Asn Ala Ala Glu Arg 450 455 460 Ala Leu Arg Ala Val Cys Leu Gly Lys Lys Asn Phe Met Phe Phe Gly 465 470 475 480 Ser Asp His Gly Gly Glu Arg Gly Ala Leu Leu Tyr Gly Leu Ile Gly 485 490 495 Thr Cys Arg Leu Asn Gly Ile Asp Pro Glu Ala Tyr Leu Arg His Ile 500 505 510 Leu Ser Val Leu Pro Glu Trp Pro Ser Asn Arg Val Asp Glu Leu Leu 515 520 525 Pro Trp Asn Val Val Leu Thr Asn Lys * 530 535 <210> 174 <211> 243 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33144..33872) <400> 174 Met Lys Leu Ala Arg Gln Gln Arg Phe Gly Lys Lys Cys Glu Ser Leu 1 5 10 15 Ala Gly Met Gln Arg Ser Leu Phe Glu Glu Asp Val Asp Ala Asp Ile 20 25 30 Ala Glu Ile Ser Ala His Leu Asp Lys Leu Leu Pro Gln Thr Gly Asp 35 40 45 Glu Glu Lys Thr Thr Thr Arg Pro Val Arg Lys Pro Leu Pro Ser Pro 50 55 60 Leu Pro Arg Ala Glu Lys Val Ile Pro Pro Ala Glu Glu Arg Cys Pro 65 70 75 80 Asp Cys Asp Ala Pro Leu His Phe Ile Arg Asp Glu Val Ser Glu Lys 85 90 95 Leu Glu Tyr Ile Pro Ala Gln Val Val Val Asn Arg Tyr Ile Arg Pro 100 105 110 Gln Tyr Ser Cys Pro Cys Cys Glu Lys Val Phe Ser Gly Lys Met Pro 115 120 125 Ala His Ile Leu Pro Lys Ser Ala Val Glu Pro Ser Val Ile Ala Gln 130 135 140 Val Val Ile Ser Lys Tyr Thr Asp His Leu Pro Leu Tyr Arg Gln Gln 145 150 155 160 His Ile Phe Ser Arg Met Gly Val Glu Leu Pro Val Ser Thr Met Ala 165 170 175 Asp Met Val Gly Val Ala Gly Ala Ala Leu Ala Pro Leu Ala Lys Leu 180 185 190 Leu Arg His Glu Leu Leu Thr Arg Asp Val Ile His Ala Asp Glu Thr 195 200 205 Ser Leu Arg Leu Leu Asp Thr Arg Lys Gly Gly Lys Ser Cys Ser Gly 210 215 220 Trp Leu Trp Ala Tyr Val Ser Gly Glu Arg Val Ser Val Asn Gly Ala 225 230 235 240 Pro Tyr * <210> 175 <211> 121 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34083..34445) <400> 175 Met Phe Ser Gly Leu Phe Ala Met Leu Thr Pro Asp Asn Val Phe Leu 1 5 10 15 Val Val Lys Pro Val Asp Met Arg Arg Gly Ile Asp Thr Leu Thr Gln 20 25 30 Tyr Val Gln Asn Glu Leu Asn Ala Ala Trp His Asp Gly Ala Ala Phe 35 40 45 Val Phe Thr Asn Lys Val Arg Ser Arg Ile Lys Val Leu Arg Trp Asp 50 55 60 Lys His Gly Val Trp Leu Cys Thr Arg Arg Leu His Arg Gly Ser Phe 65 70 75 80 Arg Trp Pro Arg Lys Gly Asp Ala Thr Trp His Leu Thr Gln Asp Glu 85 90 95 Phe His Trp Leu Val Phe Gly Val Asp Trp Gln Gln Val Lys Gly His 100 105 110 Asp Leu Ala Lys Trp Val Tyr Gln * 115 120 <210> 176 <211> 110 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34411..34740) <400> 176 Met Ser Lys Pro Arg Trp Thr Leu Asp Gln Lys Lys His His Val Ala 1 5 10 15 Ala Trp Arg Ala Ser Gly Leu Thr Arg Glu Gln Tyr Cys Glu Leu Tyr 20 25 30 Asp Ile Pro Phe Lys Ser Leu Arg Gln Trp Pro Gln Asp Val Ala Lys 35 40 45 Ala Glu Lys Arg Ala Arg Ala Pro Glu Ile Ile Pro Val Ser Val Ser 50 55 60 Gly Ser Ser Gly Met Thr Asp Gly Arg Pro Leu Ser Asp Glu Pro Val 65 70 75 80 Thr Leu Phe Leu Pro Gly Gly Ile Arg Met Cys Cys Gln Pro Ser Gln 85 90 95 Leu Thr Asp Val Phe Arg Ala Leu Arg His Ala Asp Ala * 100 105 <210> 177 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35001..35468) <400> 177 Met Gln Leu Asn Thr Arg Gln Ala Arg Ile Phe Lys Leu Ala Asn Leu 1 5 10 15 Leu Gly Thr Gly Lys Pro Val Ser Ala Ala Asp Ile Ile Thr Ser Leu 20 25 30 Glu Cys Ser Glu Pro Thr Leu Thr Arg Ala Leu Lys Glu Leu Arg Glu 35 40 45 Ser Tyr Ser Ala Glu Ile Lys Tyr Ser Lys Ala Gly His Ser Tyr His 50 55 60 Leu Val Asn Pro Gly Gln Leu Asp Lys Lys Thr Leu Arg Arg Met Asn 65 70 75 80 Glu Ala Leu Ala Gln Asn Ala Glu Leu Lys Thr Gly Glu Ser Thr Gly 85 90 95 Lys Val Val Leu Asp Lys Asp Lys Lys Thr Ala Val Ser Leu Ser Leu 100 105 110 Arg Met Arg Ile Leu Arg Lys Ile Asp Arg Leu Ala Ala Leu Ser Asp 115 120 125 Ser Thr Arg Ser Glu Ala Val Glu Lys Leu Ala Leu His Ser Val Asp 130 135 140 Glu Leu Ile Lys Glu Tyr Ser Ala Lys Lys Ser * 145 150 155 <210> 178 <211> 403 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35486..36694) <400> 178 Met Gly Phe Arg Phe Arg Lys Ser Ile Asn Ile Ile Pro Gly Val Arg 1 5 10 15 Leu Asn Leu Ser Asn Gly Ala Pro Ser Leu Ser Val Gly Pro Arg Gly 20 25 30 Ala Ser Val Ser Phe Gly Ser Arg Gly Thr Tyr Ala Asn Leu Gly Leu 35 40 45 Pro Gly Thr Gly Leu Ser Tyr Arg Thr Arg Leu Asp Arg Ala Ala Arg 50 55 60 Ser Arg Gly Glu Asn Arg Thr Ala Thr Asp Pro Gly Leu Arg Gln Ala 65 70 75 80 Leu Glu Gln Lys Ala Ala Glu Leu Met Ser Ala Val Thr Ala Ile Arg 85 90 95 Asn Ile His Glu Leu Thr Pro Asp Pro Lys Thr Gly Ile Ser Trp Ala 100 105 110 Glu Leu Glu Ala Val Tyr Leu His Asn Arg Thr Ser Pro Phe Gln Val 115 120 125 Pro Ala Pro Val Arg Pro Glu Lys Pro Asp Tyr Leu Val Leu Pro Glu 130 135 140 Lys Pro Ala Glu Ser Glu Gly Ile Ser Phe Leu Gly Lys Trp Phe Glu 145 150 155 160 Ser Glu Ser Ala Lys Ala Glu Arg His Ala Glu Asn Leu Arg Arg Trp 165 170 175 Gln Gln Glu Leu Ile Asp Val Glu Arg Glu Asn Thr Leu Arg Gln His 180 185 190 Arg Tyr Gln Gln Gln Arg Thr Ala Trp Ala Glu Gln Tyr Ala Asn Trp 195 200 205 Lys Phe Glu Ala Glu Glu His Glu Lys Arg Leu Ala Thr Ala Gln Ala 210 215 220 Asp Ala Arg Gln Gln Phe Arg Thr Asp Ala Ala Phe Phe Glu Ser Tyr 225 230 235 240 Leu Ala Gly Val Leu Ala Glu Thr Glu Trp Pro Arg Glu Thr Leu Val 245 250 255 Ala Phe Glu Val Lys Pro Glu Leu Ser Ala Val Leu Leu Asp Val Asp 260 265 270 Leu Ala Glu Ile Glu Asp Phe Pro Asp Lys Ile Tyr Gly Val Asn Ala 275 280 285 Arg Gly Thr Glu Leu Thr Glu Lys Ala Met Thr Gln Lys Ala Val Arg 290 295 300 Glu Asn Tyr Ala His His Val His Gly Cys Leu Phe Arg Leu Val Gly 305 310 315 320 Ile Val Leu His Thr Leu Pro Phe Asp Asn Val Ile Val Ser Gly Phe 325 330 335 Thr Gln Arg Val Ser Lys Arg Thr Gly Tyr Leu Glu Asp Glu Tyr Ile 340 345 350 Leu Ser Cys Lys Cys Thr Arg Ser Gln Met Ser Ser Val Asn Phe Ala 355 360 365 Gly Ile Lys His Ile Asp Pro Val Glu Ala Leu Gly Asp Gln Pro Val 370 375 380 Ile Arg Lys Met Ser Ser Thr Phe Ile Phe Gln Pro Ile Glu Pro Leu 385 390 395 400 Thr Leu * <210> 179 <211> 319 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36705..37661) <400> 179 Met Lys Asn Arg Leu Ser Pro Trp Asn Leu Gly Ala Thr Leu Tyr Met 1 5 10 15 Pro Ala Thr Arg Glu Asp Ile Ala Asp Ala Val Leu His Gly Lys Ile 20 25 30 Pro Gly Leu Arg Ser Leu Val Ile Cys Leu Glu Asp Ala Val Ser Glu 35 40 45 Ala Asp Ile Pro Val Ala Leu Lys Asn Leu Glu His Leu Leu His Glu 50 55 60 Leu Ser Asn Ser Met Ser Ser Leu Gly Lys Asn Asp Trp Pro Leu Val 65 70 75 80 Phe Ile Arg Pro Arg His Ala Glu Met Gly Arg Trp Leu Lys Ala His 85 90 95 Tyr Asp Leu Ser Ala Val Asp Gly Phe Val Leu Pro Lys Phe Thr Leu 100 105 110 Ser Ser Leu Ala Glu Trp Trp Asp Ile Met Val Gly Thr His Leu Cys 115 120 125 Met Met Pro Thr Leu Glu Thr Glu Asp Val Phe Asp Val Val Gln Met 130 135 140 Arg Glu Leu Ala Thr Arg Leu Glu Glu His Pro Cys His Asp Arg Ile 145 150 155 160 Ile Ala Leu Arg Ile Gly Gly Asn Asp Leu Met Asn Val Val Ser Leu 165 170 175 Arg Arg Pro Arg Asp Leu Thr Leu Tyr Asp Ser Pro Met Gly Tyr Val 180 185 190 Ile Lys Met Leu Val Ser Val Phe Gly Pro Arg Asp Phe Ala Leu Thr 195 200 205 Ala Pro Val Cys Glu His Ile Asp Asp His Ala Val Met Ala Arg Glu 210 215 220 Leu Ala Leu Asp Met Ala His Gly Leu Val Gly Lys Thr Ala Ile His 225 230 235 240 Pro Gly Gln Ile Glu Val Ile Gln Asn Ala Leu Met Val Thr Gln Gly 245 250 255 Glu His Ser Asp Ala Leu Arg Ile Leu Asn Ser Thr Gln Ala Val Phe 260 265 270 Lys Ser Gln Gly Ala Met Cys Glu Pro Ala Thr His Arg Arg Trp Ala 275 280 285 Ala Gly Ile Leu Asp Arg Ala Arg Phe Tyr Gly Leu Gln Asn Glu Gln 290 295 300 Ser Ala Asp Gly Ile Arg Leu Leu Thr Val Thr Gln His His * 305 310 315 <210> 180 <211> 245 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37661..38395) <400> 180 Met Gly Lys Thr Ser Trp His Tyr Gly Ile Ser Ile Ile Arg Asp Arg 1 5 10 15 Gly Ile Asp Gly Ala Ala Leu Asp Val Ile Glu Glu Arg His Gly Thr 20 25 30 Ser Gly Ile Val Phe Val Asp Gly Trp Thr Gly Lys Gly Ala Ile Thr 35 40 45 Gly Glu Leu Val Arg Ala Leu Lys Asp Arg Pro Gly Tyr Pro Glu Gln 50 55 60 Pro Arg Leu Val Val Leu Ala Asp Pro Cys Gly Cys Ser Trp Leu Ala 65 70 75 80 Ala Ser Asp Asp Asp Trp Leu Ile Pro Phe Gly Ile Met Gly Ala Pro 85 90 95 Val Ser Gly Leu Ile Ser Arg Ser Val Trp Ser Ser Glu Gly Leu His 100 105 110 Gly Cys Met Val Cys Glu His Leu Ser Glu Phe Glu Cys Ser Arg Met 115 120 125 Leu Ala Asp Thr Val Ala His Phe Arg Lys Lys Leu Thr Pro Ser Ser 130 135 140 Leu Ala Pro Leu Ser Trp Asn Thr Glu Ser Ala Arg Val Leu Trp Gln 145 150 155 160 Thr Ser Arg Asp Val Ile Ala Phe Leu Ala Asp Glu Phe Lys Val Asp 165 170 175 Ser Val Asn Arg Ile Lys Pro Gly Ile Ala Glu Ala Thr Arg Ala Val 180 185 190 Leu Arg Arg Val Pro Asp His Val Phe Val Arg Ser Ile Asp Asp Pro 195 200 205 Asp Val Ala Leu Leu Val Gly Leu Ala Arg Glu Lys Gly Ile Val Val 210 215 220 Thr Glu Met Gly Gly Thr Leu Gly Gln Tyr Arg Ala Val Thr Ile Ile 225 230 235 240 Lys Lys Val Leu * <210> 181 <211> 127 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38397..38777) <400> 181 Met Pro Phe His Ser Glu Phe Leu Glu Lys Ile Lys Met Gln Pro His 1 5 10 15 Glu Thr Phe Thr Gly Ser Tyr Gln Pro Gly Asp Val Glu Phe Leu Leu 20 25 30 Lys Pro Val Val Ile Glu Met Thr Pro Val Glu Lys Lys Glu Glu Leu 35 40 45 Ile Gln Ser Gly Lys Lys His Tyr Ser Asp Met Leu Ser Gln Glu Pro 50 55 60 Ala Pro Thr Gln Trp His Leu Asp Leu Phe His Arg Ala Leu Asp Arg 65 70 75 80 Gly Ala Glu Arg Leu Ala Lys Glu Val Thr Gln Leu Ala Ile Ala Leu 85 90 95 Ala Glu Arg Phe Gly Asp Glu Pro Ile Val Leu Ala Ser Leu Val Arg 100 105 110 Ala Gly Val Pro Leu Gly Arg Tyr Ala Ala Pro Gly Pro Ala * 115 120 125 <210> 182 <211> 258 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38743..39516) <400> 182 Met Asn Lys Pro Val Val Leu Ser Asp Leu Asp Asp Thr Leu Phe Gln 1 5 10 15 Thr Arg Arg Lys Met Val Asp Glu Leu Ala Leu Glu Pro Phe Arg Thr 20 25 30 Gly Ala Val Asp Arg Thr Leu Asn Pro Arg Ser Phe Met Thr Glu Glu 35 40 45 Gln Ser Met Leu Val Asp Trp Leu Leu Glu Gln Ala Glu Leu Ile Pro 50 55 60 Val Thr Ala Arg Gly Thr Glu Glu Ile Ser Arg Val Arg Ile Pro Phe 65 70 75 80 His Ser Trp Ala Ile Thr Thr His Gly Ala Val Ile Leu Thr Pro Glu 85 90 95 Gly Lys Pro Asp Glu Glu Trp Lys Ala His Met Leu Gly Gln Leu Ala 100 105 110 Pro Tyr Gln Glu Lys Leu Thr Ser Met Gln Arg Leu Ile Thr Glu Met 115 120 125 Met Asp Ala Lys Gly Ile Asn Ala Trp Ala Arg Leu Asn Phe Glu Tyr 130 135 140 Gly Glu Met Ala Val Tyr Met Val Met Lys His Arg Asp Ser Thr Arg 145 150 155 160 Leu Asp Glu Leu Asn Ala Ile Ala Asp Glu Ile Glu Thr Val Phe Pro 165 170 175 Thr Glu Gly Phe Tyr Ile His Arg Asn Ser Asn Asn Val Ala Trp Leu 180 185 190 Pro Thr Pro Val Glu Lys Gly Leu Ala Val Ser Trp Leu Leu Glu Lys 195 200 205 Leu Arg Ala Glu Arg Gly Val Phe Pro Val Ile Gly Leu Gly Asp Ser 210 215 220 Leu Ser Asp His Arg Phe Met Lys Leu Cys Ser Trp Phe Gly Ile Pro 225 230 235 240 Arg Gln Ser Gln Phe Ala Asp Ala Ile Ser Gln Arg Ile Phe Gly Glu 245 250 255 Asn * <210> 183 <211> 381 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39509..40651) <400> 183 Met Ser Asp Ile Leu Glu Asp Met Ile Tyr Arg Arg Thr Leu Ser Cys 1 5 10 15 Gly Thr Ile Gln Val Thr Arg Asp Gln Gly Glu Val Ser Leu Asp Asp 20 25 30 Leu Phe Asp Ile Ala Glu Arg Arg Asn Pro Lys Arg Ala Phe Leu Phe 35 40 45 Val Ser Lys Val Leu Gly Arg His Ile Pro Val Pro Pro Ser Val Met 50 55 60 Arg Gln Ala Tyr Arg Gln Leu Ala Ser Gln Phe Pro Ser Thr Leu Thr 65 70 75 80 Gly Pro Val Leu Phe Ile Gly Met Ala Glu Thr Ala Val Gly Leu Gly 85 90 95 Ala Gly Val Phe Asp Glu Val Arg His Gln His Arg Glu Ser Val Tyr 100 105 110 Leu Thr Ser Thr Arg His Pro Val Asp Gly Thr Leu Leu Cys Glu Phe 115 120 125 Lys Glu Glu His Ser His Ala Thr Asp His Leu Ile Tyr Leu Pro Asp 130 135 140 Asp Glu Glu Lys Arg Arg Arg Val Thr Asn Ala Arg Thr Leu Val Leu 145 150 155 160 Ile Asp Asp Glu Ala Thr Thr Gly Asn Thr Phe Ile Asn Leu Leu Ser 165 170 175 Ala Leu Arg Asn Thr Gly Lys Leu Gln His Ile Glu Gln Val Ile Ala 180 185 190 Val Thr Leu Thr Asp Trp Ser Gly Asn Ala Leu Ser Glu Arg Thr Pro 195 200 205 Leu Pro Val Thr Ser Val Ser Leu Val Ser Gly Gln Trp Gly Trp Thr 210 215 220 Pro Leu Pro Asp Ala Pro Val Pro Asp Met Pro Lys Val Asn Val Thr 225 230 235 240 Ser Arg Gly Glu Trp Asp Ile Gln Gly Lys Gln Ser Trp Gly Arg Leu 245 250 255 Gly Met Leu Ala Pro Ala Ala Asp Leu Gly His Glu Val Ser Val His 260 265 270 Lys Gly Glu Arg Ile Leu Val Leu Gly Thr Gly Glu Phe Val Trp Glu 275 280 285 Pro Phe Leu Leu Ala Glu Arg Leu Glu Ala Ala Gly Ala Gln Ala Phe 290 295 300 Tyr Gly Ser Thr Thr Arg Ser Pro Val Ala Val Gly Tyr Ala Ile Glu 305 310 315 320 Ser Ala Ile Ser Phe Thr Asp Asn Tyr Gly Leu Gly Ile Pro Asn Phe 325 330 335 Val Tyr Asn Val Ala His Gln Gln Phe Asp Arg Ile Leu Val Cys Thr 340 345 350 Glu Thr Pro Ala Glu Ser Ile Asp Thr Gln Leu Leu Lys Ala Leu Ala 355 360 365 Glu Val Ala Pro Val Val Glu Ile Val Thr Tyr Glu * 370 375 380 <210> 184 <211> 353 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40661..41719) <400> 184 Met Asn Lys Lys Ile Trp Phe Met Glu Gly Leu Ser Ser Gln Arg Asp 1 5 10 15 Ile Ile Gln Gly Val Lys Ser Phe Ala Gln Lys Asn Asn Phe Ala Ile 20 25 30 Thr Val Phe Ala Ser His Arg Asn Glu Arg Asn Glu Ile Leu Ser Val 35 40 45 Ala Asp Tyr Ser Leu Thr Glu Pro Glu Asp Pro Gln Lys Arg Leu Gln 50 55 60 Phe Ile Gln Glu Thr Ile Gln Thr Tyr Gly Ile His His Ile His Thr 65 70 75 80 Gly Arg Asn Ser Gln Trp Phe Glu Glu His Arg Ser Ala Ile Glu Pro 85 90 95 Thr Gly Ala Thr Leu Thr Thr Gly Ala Thr Gly Val Asp Trp Leu Thr 100 105 110 Leu Ala Asp Glu Lys Val Thr Phe Ala Gln Phe Met Glu Gln Lys Gly 115 120 125 Leu Pro Val Val Pro Ser Trp Arg Val Asn Thr Leu Ala Glu Leu Lys 130 135 140 Thr His Leu Ala Ala Pro Pro Phe Thr Asp Ser Pro Val Cys Val Lys 145 150 155 160 Pro Val Thr Gly Ile Tyr Gly Met Gly Phe Trp Arg Phe Asp Asp Ser 165 170 175 Ala Ser Pro Met Ala Val Phe Asn His Pro Glu His Arg Leu Val Ser 180 185 190 Pro Gln Gln Tyr Ile Ala Ala Ala Ser Ala Ala Glu Ser Phe Lys Pro 195 200 205 Leu Val Leu Met Pro Tyr Leu Pro Gly Pro Glu Phe Ser Val Asp Ile 210 215 220 Leu Ala Asp Lys Gly Glu Ile Leu Ala Ala Val Gly Arg Arg Lys Glu 225 230 235 240 Gly Ala Ile Gln Tyr Leu Val Asn Glu Gly Ser Ala Trp Glu Leu Ala 245 250 255 Cys Asp Cys Ala Arg Val Met Lys Ala Asp Gly Leu Val Asn Val Gln 260 265 270 Thr Arg Asn Asp Val Asn Gly Asn Pro Val Leu Leu Glu Thr Asn Met 275 280 285 Arg Pro Ser Gly Gly Val Gly Tyr Thr Leu His Ser Gly Val Asn Leu 290 295 300 Pro Gly Leu Phe Ala Ala Phe Lys Leu Gly Leu Met Ser Glu Asp Met 305 310 315 320 Val Arg Gln Ser Ala Lys Asn Thr Phe Ser Pro Val Ala Val Arg Ser 325 330 335 Ile Thr Asp Val Ile Ala Tyr Pro Glu Ser Leu Ser Asn Leu Leu Asn 340 345 350 * <210> 185 <211> 194 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42042..42623) <400> 185 Met Val Ser Leu Val Lys Asn Gln Thr Val Ser Leu Ser Lys Glu Ser 1 5 10 15 Ser Ala Leu Ser Gln Leu His Phe Gly Leu Gly Trp Asp Pro Val Lys 20 25 30 Lys Lys Gly Leu Leu Gly Gly Leu Phe Gly Gly Asn Asp Ser Ile Asp 35 40 45 Leu Asp Ala Gly Cys Val Leu Met Asp Ser Thr Gly Lys Thr Ile Asp 50 55 60 Thr Ile Trp Phe Arg Lys Leu Lys Ser Thr Cys Gly Ala Val Val His 65 70 75 80 Ser Gly Asp Asn Leu Thr Gly Glu Gly Asp Gly Asp Asp Glu Val Ile 85 90 95 Lys Val Asn Leu Ser Arg Leu Pro Ala Asn Val Glu Tyr Leu Ala Phe 100 105 110 Thr Val Asn Ser Phe Arg Gly Gln Ser Phe Asn Asp Val Glu Asn Ala 115 120 125 Phe Cys Arg Val Val Asp Gln Thr Gly Lys Glu Leu Ala Arg Tyr Lys 130 135 140 Leu Thr Glu Gln Gly Ser His Thr Gly Ile Val Ile Ser Ser Leu Arg 145 150 155 160 Arg Asn Asn Gly Asn Trp Asp Phe Thr Ala Leu Gly His Ala Cys Arg 165 170 175 Gly Arg Thr Ile Asp Asp Met His Ser Asp Ile Val Ser Ala Val Ile 180 185 190 Arg * <210> 186 <211> 342 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42755..43780) <400> 186 Met Val Phe Tyr Gly Gln Pro Arg Asn Asp Asp Gly Thr Val Ser Leu 1 5 10 15 Val Ser Glu Gly Gln Tyr Ser Thr Phe Thr Val Ala Leu Asn Arg Leu 20 25 30 Lys Pro Asp Val Gln Lys Ile Ala Phe Thr Val Thr Cys Asp Gly Gly 35 40 45 Gln Thr Val Ser Gly Leu Arg Asn Leu Ser Ile Asp Val Glu Gln Gly 50 55 60 Ala Thr Gly Leu Val Ser Gly Ser Val Glu Leu Ser Gly Arg Gln Glu 65 70 75 80 Ala Ala Leu Ile Leu Gly Glu Phe Tyr Arg Arg Asn Asn Asp Trp Lys 85 90 95 Phe Arg Phe Val Ala Gln Gly Phe Asn Gly Gly Leu Lys Pro Leu Ala 100 105 110 Glu His Phe Gly Val Asn Ile Ala Asp Glu Pro Ala Pro Ala Ala Pro 115 120 125 Thr Pro Pro Val Val Thr Pro Pro Pro Val Glu Thr Lys Ile Ser Leu 130 135 140 Ser Lys Val Ser Leu Thr Lys Glu Lys Pro Ala Ile Ser Leu Thr Lys 145 150 155 160 Arg Asp Asn Phe Gly Glu Ile Arg Ile Asn Leu Asn Trp His Arg Gly 165 170 175 Ser Ser Lys Ser Gly Phe Ala Gly Met Phe Gly Ser Lys Gly Ile Asp 180 185 190 Leu Asp Leu Gly Ala Phe Val Glu Leu Gln Asp Gly Tyr Lys Ser Val 195 200 205 Ile Gln Ala Leu Gly Asn Ala Phe Gly Asp Tyr Arg Asp Glu Pro Tyr 210 215 220 Val Gln Leu Lys Gly Asp Asp Arg Thr Gly Asp Val Ser Asp Gly Glu 225 230 235 240 Trp Leu His Ile Asn Gly Arg Glu Trp Lys His Ile Arg Glu Val Leu 245 250 255 Ile Tyr Ala Phe Ile Tyr Glu Gly Val Pro Ser Trp Asp Lys Thr Asp 260 265 270 Gly Val Val Thr Ile His Val Pro Asp Gln Pro Pro Ile Glu Thr Arg 275 280 285 Leu Thr Glu Gly Glu Asn Arg Arg Thr Leu Cys Ala Ile Ala Arg Leu 290 295 300 Val Asn Glu Asn Gly Ala Ile Lys Val Glu Arg Ile Asn Gln Tyr Phe 305 310 315 320 Lys Gly Gln Asp Glu Met Asp Arg Ala Phe Gly Trp Gly Phe Arg Trp 325 330 335 Ser Ala Gly Ser Lys * 340 <210> 187 <211> 152 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43803..44258) <400> 187 Met Ser Phe Phe Asp Lys Val Lys Gly Ala Ile Asn Ser Gly Arg Asp 1 5 10 15 Glu Leu Thr Arg Gln Val Gly Arg Phe Lys Asn Lys Lys Phe Met Gln 20 25 30 Gly Thr Val Ala Val Cys Ala Arg Ile Ala Val Ser Ser Asp Gly Val 35 40 45 Ser Ser Glu Glu Lys Gln Lys Met Met Gly Phe Leu Arg Ser Ser Glu 50 55 60 Glu Leu Lys Val Phe Asp Thr Asn Glu Val Ile Glu Phe Phe Asn Lys 65 70 75 80 Leu Val Ser Ser Phe Asp Phe Asp Val Glu Ile Gly Lys Gly Glu Thr 85 90 95 Met Lys Tyr Ile Leu Ala Leu Lys Asp Gln Pro Glu Ala Ala Gln Leu 100 105 110 Ala Leu Arg Val Gly Ile Ala Val Ala Lys Ser Asp Gly Asn Phe Asp 115 120 125 Gln Asp Glu Lys Leu Ala Ser Arg Glu Ile Ala Ile Ala Leu Gly Phe 130 135 140 Asp Pro Ala Glu Phe Gly Leu * 145 150 <210> 188 <211> 347 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44281..45321) <400> 188 Met Val Ser Thr His Ile Gly Phe Pro Thr Glu Thr Val Ile Val Phe 1 5 10 15 Ile Ala Leu Ser Val Gly Ala Ile Phe Ile Asp Leu Phe Met His Arg 20 25 30 Asp Asp Lys Pro Ile Ser Leu Lys Ser Ala Ala Leu Trp Ser Val Phe 35 40 45 Trp Val Val Val Ala Met Ala Phe Ala Gly Phe Leu Tyr Ile His His 50 55 60 Gly Ala Glu Val Ala Ser Leu Phe Val Thr Gly Tyr Ala Leu Glu Lys 65 70 75 80 Val Leu Ser Val Asp Asn Leu Phe Val Met Met Ala Ile Phe Ser Trp 85 90 95 Phe Ala Val Pro Asp Arg Tyr Arg His Arg Val Leu Tyr Trp Gly Ile 100 105 110 Ile Gly Ala Ile Val Phe Arg Gly Ile Phe Val Ala Ile Gly Thr Ser 115 120 125 Leu Leu Ser Leu Gly Pro Tyr Val Glu Val Val Phe Ala Ile Ile Val 130 135 140 Ala Trp Thr Ala Val Met Met Leu Lys Ser Gly Asp Asp Asp Asp Glu 145 150 155 160 Ile Glu Asp Tyr Ser Gln His Leu Ala Tyr Arg Met Val Lys Arg Phe 165 170 175 Phe Pro Ile Trp Pro Lys Leu Arg Gly His Ala Phe Leu Leu Asn Gln 180 185 190 Lys Glu Val Asp Ala Glu Leu Ala Lys Pro Glu Asn Ser Asp Val Thr 195 200 205 Ile Gly Arg Gly Lys Lys Ala Ala Leu Tyr Ala Thr Pro Leu Phe Leu 210 215 220 Cys Val Ala Val Val Glu Leu Ser Asp Val Met Phe Ala Phe Asp Ser 225 230 235 240 Val Pro Ala Ile Ile Ala Val Ser Arg Glu Pro Leu Ile Val Tyr Ser 245 250 255 Ala Met Met Phe Ala Ile Leu Gly Leu Arg Thr Leu Tyr Phe Val Leu 260 265 270 Glu Ala Leu Lys Gln Tyr Leu Val His Leu Glu Lys Ala Val Ile Val 275 280 285 Leu Leu Phe Phe Ile Ala Ala Lys Leu Gly Leu Asn Ala Thr Asp His 290 295 300 Ile Trp His His Gly Tyr Ser Ile Ala Ala Thr Thr Ser Leu Tyr Val 305 310 315 320 Val Leu Gly Val Leu Ala Leu Gly Ile Leu Ala Ser Val Met Phe Pro 325 330 335 Gly Lys Pro Glu Ser Glu Glu Lys Gly Ser * 340 345 <210> 189 <211> 193 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45370..45948) <400> 189 Met Ser Val Ser Leu Ser Lys Gly Gly Asn Val Ser Leu Ser Lys Ala 1 5 10 15 Ala Pro Ser Met Lys Asn Val Leu Val Gly Leu Gly Trp Asp Ala Arg 20 25 30 Ser Thr Asp Gly Gln Asp Phe Asp Leu Asp Ala Ser Ala Phe Leu Leu 35 40 45 Ala Ser Asn Gly Lys Val Arg Gly Asp Ser Asp Phe Ile Phe Tyr Asn 50 55 60 Asn Leu Thr Ser Ser Asp Gly Ser Val Thr His Thr Gly Asp Asn Arg 65 70 75 80 Thr Gly Glu Gly Asp Gly Asp Asp Glu Ser Leu Lys Ile Lys Leu Asp 85 90 95 Ala Val Pro Ser Glu Val Asp Lys Ile Ile Phe Val Val Thr Ile His 100 105 110 Asp Ala Gln Ala Arg Arg Gln Ser Phe Gly Gln Val Ser Gly Ala Phe 115 120 125 Ile Arg Leu Val Asn Asp Asp Asn Gln Thr Glu Val Ala Arg Tyr Asp 130 135 140 Leu Thr Glu Asp Ala Ser Thr Glu Thr Ala Met Leu Phe Gly Glu Leu 145 150 155 160 Tyr Arg His Asn Gly Glu Trp Lys Phe Arg Ala Val Gly Gln Gly Tyr 165 170 175 Ala Gly Gly Leu Ala Ser Val Cys Ala Gln Tyr Gly Ile Asn Ala Ser 180 185 190 * <210> 190 <211> 192 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46017..46592) <400> 190 Met Ala Val Ser Leu Val Lys Gly Gly Asn Val Ser Leu Thr Lys Glu 1 5 10 15 Ala Pro Thr Met Asn Val Ala Met Val Gly Leu Gly Trp Asp Ala Arg 20 25 30 Val Thr Asp Gly Gln Gly Phe Asp Leu Asp Ala Ser Val Phe Ala Val 35 40 45 Gly Glu Asp Gly Lys Val Leu Ser Asp Ala His Phe Ile Phe Phe Asn 50 55 60 Asn Lys Thr Ser Pro Asp Gly Ala Val Glu His Gln Gly Asp Asn Arg 65 70 75 80 Thr Gly Glu Gly Asp Gly Asp Asp Glu Gln Val Lys Ile Asp Leu Thr 85 90 95 Lys Val Ser Ala Asp Ile Lys Lys Leu Val Phe Ala Val Thr Ile Tyr 100 105 110 Asp Ala Glu Ala Arg Lys Gln Asn Phe Gly Met Val Ser Asn Ser Phe 115 120 125 Met Arg Val Tyr Asn Asn Asp Asn Gly Thr Glu Ile Ala Arg Phe Asp 130 135 140 Leu Ser Glu Asp Ala Ser Thr Glu Thr Ala Met Val Phe Gly Glu Leu 145 150 155 160 Tyr Arg His Gly Thr Glu Trp Lys Phe Lys Ala Val Gly Gln Gly Phe 165 170 175 Ala Gly Gly Leu Ser Ala Leu Ala Ser Gln His Gly Val Asn Val * 180 185 190 <210> 191 <211> 68 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46617..46820) <400> 191 Met Pro Gly Phe Phe Leu Gly Ile Asp Pro Leu Ser Thr Gly Glu Tyr 1 5 10 15 Gly Lys Gly Gly Gly Arg Lys Gln Ser Tyr Val Asn Ser Gly Met Asn 20 25 30 Leu Leu Cys Arg Pro Arg Val Tyr Leu Trp Leu Leu Val Lys Ala Ser 35 40 45 Ile Pro Cys Leu Ile Ser Thr Ala Cys Pro Ser Asp Ile Cys Tyr Phe 50 55 60 Cys Asp Leu * 65 <210> 192 <211> 103 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(47014..47322) <400> 192 Met Asn Leu Gln Ser Gly Gln Asn Ile Pro Leu Gln Gln Ser Thr Ile 1 5 10 15 Arg Leu Asn Leu Gln Tyr Pro Ala Lys Ser Gly Phe Lys Gly Glu Pro 20 25 30 Asp Thr Cys Leu Phe Met Leu Asn Ala Gln Gly Lys Val Ser Gly Asp 35 40 45 Ser Asp Phe Ile Phe Tyr Asn Asn Leu Ser Ser Pro Glu Gly Ala Val 50 55 60 Arg Leu Val Thr Gly Ser Gln Gln Ala Ser Ile Glu Ile Ala Leu Asp 65 70 75 80 Arg Val Pro Ala Asn Val Ser Lys Ile Ala Ile Thr Val Val Ile Asp 85 90 95 Gly Glu Asp Thr Ile Ser * 100 <210> 193 <211> 75 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(47456..47680) <400> 193 Val Thr Phe Gln Gly Asn Asn Ser Phe Met Arg Leu Ala Gly Gln Val 1 5 10 15 Leu Ile Thr Leu Ile Thr Trp Arg Ser His Val Ser Gly Ser Ile Pro 20 25 30 Leu Ser Phe Ala Ala Thr Asp Gln Ala Val His His Cys Arg Thr Ile 35 40 45 Ala Arg His Leu Lys Val Leu Ser Arg Gln Gln Glu Gly Ile Ile Leu 50 55 60 Ser Arg His Phe Ser Arg Gly Pro Val Arg * 65 70 <210> 194 <211> 697 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(47914..50004) <400> 194 Met Arg Ile Thr Thr Leu Ala Ser Val Val Ile Pro Cys Leu Gly Phe 1 5 10 15 Ser Ala Ser Ser Ile Ala Ala Ala Glu Asp Val Met Ile Val Ser Ala 20 25 30 Ser Gly Tyr Glu Lys Lys Leu Thr Asn Ala Ala Ala Ser Val Ser Val 35 40 45 Ile Ser Gln Glu Glu Leu Gln Ser Ser Gln Tyr His Asp Leu Ala Glu 50 55 60 Ala Leu Arg Ser Val Glu Gly Val Asp Val Glu Ser Gly Thr Gly Lys 65 70 75 80 Thr Gly Gly Leu Glu Ile Ser Ile Arg Gly Met Pro Ala Ser Tyr Thr 85 90 95 Leu Ile Leu Ile Asp Gly Val Arg Gln Gly Gly Ser Ser Asp Val Thr 100 105 110 Pro Asn Gly Phe Ser Ala Met Asn Thr Gly Phe Met Pro Pro Leu Ala 115 120 125 Ala Ile Glu Arg Ile Glu Val Ile Arg Gly Pro Met Ser Thr Leu Tyr 130 135 140 Gly Ser Asp Ala Met Gly Gly Val Val Asn Ile Ile Thr Arg Lys Asn 145 150 155 160 Ala Asp Lys Trp Leu Ser Ser Val Asn Ala Gly Leu Asn Leu Gln Glu 165 170 175 Ser Asn Lys Trp Gly Asn Ser Ser Gln Phe Asn Phe Trp Ser Ser Gly 180 185 190 Pro Leu Val Asp Asp Ser Val Ser Leu Gln Val Arg Gly Ser Thr Gln 195 200 205 Gln Arg Gln Gly Ser Ser Val Thr Ser Leu Ser Asp Thr Ala Ala Thr 210 215 220 Arg Ile Pro Tyr Pro Thr Glu Ser Gln Asn Tyr Asn Leu Gly Ala Arg 225 230 235 240 Leu Asp Trp Lys Ala Ser Glu Gln Asp Val Leu Trp Phe Asp Met Asp 245 250 255 Thr Thr Arg Gln Arg Tyr Asp Asn Arg Asp Gly Gln Leu Gly Ser Leu 260 265 270 Thr Gly Gly Tyr Asp Arg Thr Leu Arg Tyr Glu Arg Asn Lys Ile Ser 275 280 285 Ala Gly Tyr Asp His Thr Phe Thr Phe Gly Thr Trp Lys Ser Tyr Leu 290 295 300 Asn Trp Asn Glu Thr Glu Asn Lys Gly Arg Glu Leu Val Arg Ser Val 305 310 315 320 Leu Lys Arg Asp Lys Trp Gly Leu Ala Gly Gln Pro Arg Glu Leu Lys 325 330 335 Glu Ser Asn Leu Ile Leu Asn Ser Leu Leu Leu Thr Pro Leu Gly Glu 340 345 350 Ser His Leu Val Thr Val Gly Gly Glu Phe Gln Ser Ser Ser Met Lys 355 360 365 Asp Gly Val Val Leu Ala Ser Thr Gly Glu Thr Phe Arg Gln Lys Ser 370 375 380 Trp Ser Val Phe Ala Glu Asp Glu Trp His Leu Thr Asp Ala Leu Ala 385 390 395 400 Leu Thr Ala Gly Ser Arg Tyr Glu His His Glu Gln Phe Gly Gly His 405 410 415 Phe Ser Pro Arg Ala Tyr Leu Val Trp Asp Val Ala Asp Ala Trp Thr 420 425 430 Leu Lys Gly Gly Val Thr Thr Gly Tyr Lys Ala Pro Arg Met Gly Gln 435 440 445 Leu His Lys Gly Ile Ser Gly Val Ser Gly Gln Gly Lys Thr Asn Leu 450 455 460 Leu Gly Asn Pro Asp Leu Lys Pro Glu Glu Ser Val Ser Tyr Glu Ala 465 470 475 480 Gly Val Tyr Tyr Asp Asn Pro Ala Gly Leu Asn Ala Asn Val Thr Gly 485 490 495 Phe Met Thr Asp Phe Ser Asn Lys Ile Val Ser Tyr Ser Ile Asn Asp 500 505 510 Asn Thr Asn Ser Tyr Val Asn Ser Gly Lys Ala Arg Leu His Gly Val 515 520 525 Glu Phe Ala Gly Thr Leu Pro Leu Trp Ser Glu Asp Val Thr Leu Ser 530 535 540 Leu Asn Tyr Thr Trp Thr Arg Ser Glu Gln Arg Asp Gly Asp Asn Lys 545 550 555 560 Gly Ala Pro Leu Ser Tyr Thr Pro Glu His Met Val Asn Ala Lys Leu 565 570 575 Asn Trp Gln Ile Thr Glu Glu Val Ala Ser Trp Leu Gly Ala Arg Tyr 580 585 590 Arg Gly Lys Thr Pro Arg Phe Thr Gln Asn Tyr Ser Ser Leu Ser Ala 595 600 605 Val Gln Lys Lys Val Tyr Asp Glu Lys Gly Glu Tyr Leu Lys Ala Trp 610 615 620 Thr Val Val Asp Ala Gly Leu Ser Trp Lys Met Thr Asp Ala Leu Thr 625 630 635 640 Leu Asn Ala Ala Val Asn Asn Leu Leu Asn Lys Asp Tyr Ser Asp Val 645 650 655 Ser Leu Tyr Ser Ala Gly Lys Ser Thr Leu Tyr Ala Gly Asp Tyr Phe 660 665 670 Gln Thr Gly Ser Ser Thr Thr Gly Tyr Val Ile Pro Glu Arg Asn Tyr 675 680 685 Trp Met Ser Leu Asn Tyr Gln Phe * 690 695 <210> 195 <211> 41 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(50808..50930) <400> 195 Met Ser Gly Lys Thr Pro Glu Phe Val Asp Val Ile Cys Phe Val Tyr 1 5 10 15 Phe Ile Thr Ile Val Cys Val Lys Ser Phe Phe Lys Leu Ile Pro Lys 20 25 30 Trp Ala Lys Pro Gly Phe Arg Lys * 35 40 <210> 196 <211> 91 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(51403..51675) <400> 196 Leu Pro Gly Asn Trp Thr Tyr Asn Tyr Ser Ser Val Leu Lys Glu Arg 1 5 10 15 Ser Glu Met Phe Lys Tyr Ala Glu Met Leu Met Ala Glu Glu Asp Asp 20 25 30 Lys Val Cys Glu Leu Ile Phe Lys Gln Gln Asp Asn Leu Ile Leu Lys 35 40 45 Ile Asn Val Arg Phe Pro Arg Ile Ile Ile Lys Lys Tyr Arg Thr Leu 50 55 60 Gln Gly Lys Val Val Trp Leu Trp Ile Leu Pro Phe Val Ile Glu Trp 65 70 75 80 Leu Ile Val Cys Thr Leu Gly Val Asn Ser * 85 90 <210> 197 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(52796..52948) <400> 197 Met Leu Tyr Asp Ala Phe Thr Val Pro Gly Gln Arg Met Pro Arg Arg 1 5 10 15 Cys Ile Trp Ile Arg Val Gly Asn Ile Glu Leu Gln Ala Ile Gly Lys 20 25 30 Val Lys Ala Pro Trp Ser Ser Thr Lys Tyr Ala Ala Gln Arg Lys Arg 35 40 45 Ser Glu * 50 <210> 198 <211> 65 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(53424..53618) <400> 198 Met Asn Glu Asn Lys Ile Lys Arg Leu Glu Gln Leu Leu Gln Ala Arg 1 5 10 15 Gln Arg Glu Phe Ala Thr Lys Trp Gly Arg Ala Ala Leu Pro His Glu 20 25 30 Arg Leu Thr Tyr Phe Pro Leu Glu Asp Leu Ile Lys Asn Asn Gly Lys 35 40 45 Lys Ile Arg Ser Asp Lys Lys His Phe Leu Glu Cys Asn Glu Asp Lys 50 55 60 * <210> 199 <211> 75 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(53698..53922) <400> 199 Leu Glu Leu Ser Ser Thr Lys Gly Asp Glu Ala Arg Leu Tyr Arg Asn 1 5 10 15 Gly Ser Met Ala Leu Met Pro Val Cys Cys Ser Ile Met Ala Ser Leu 20 25 30 Ser Ile Arg Cys Cys Ser Ser Arg Lys Asn Phe Ala Ser Ser Gly Asp 35 40 45 Lys Ser Ile Val Ile Thr Arg Lys Ala Met Arg Cys Ser Ala Leu Arg 50 55 60 Tyr Arg Ala Asp Gly Ser Tyr Pro Phe Tyr * 65 70 <210> 200 <211> 91 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(53938..54210) <400> 200 Val Ser Tyr Gln Pro Gly Gly Leu Val Leu Pro Asp Leu Ser Arg Arg 1 5 10 15 Gly Tyr Leu Ser Lys Asn Ala Ser Ser Ser Asn Arg Phe Gly Leu Val 20 25 30 Asn Gly Asp Gly Leu Ser Lys Asp Ser Arg Cys Trp Cys Thr Phe Ser 35 40 45 Arg Trp Arg Ser Ser Met Asp Asn Ala Ile Ala Cys Ser Ser Ser Leu 50 55 60 Val Ile Val Cys Thr Trp Glu Ala Ile Tyr Arg Ser Thr Ser His Tyr 65 70 75 80 Gly Lys Asn Val Leu Leu Leu Gln Leu Ala * 85 90 <210> 201 <211> 65 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(54515..54709) <400> 201 Leu Cys His Arg Ala His Gln Ser Cys Thr Thr Arg Asp Val Ala Leu 1 5 10 15 Asp Arg His Leu Pro Asp Cys Glu Asp Ile Leu Lys Glu Val Ile Trp 20 25 30 Ala Phe Ser Asp Phe Val Arg Asp Asn Arg Gly Val Tyr Asp Pro Glu 35 40 45 Ala Arg Tyr Pro Ala Gly Asn Pro Trp Tyr Pro Val Thr Gly Gln Phe 50 55 60 * <210> 202 <211> 49 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(54757..54903) <400> 202 Met Ala Phe Thr Asp Gln Leu Val Lys Pro Phe Val Gly His Thr Gly 1 5 10 15 Glu Thr Gly Asp Ile Val His Val Asp Gln Gly Ile Ile Gly Thr Gln 20 25 30 Lys Tyr Ala Val Val Ala Cys Cys Ser Gln His Gly Gln Asn Val Leu 35 40 45 <210> 203 <211> 103 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(54879..55187) <400> 203 Met Thr Asn Gln Ser Gly Arg Asp Asn Asn Pro Leu Leu Asn Gly Arg 1 5 10 15 Tyr Gln Gln Glu Asp Glu Arg Glu Tyr Arg Gln His Gln Gly Gln Gly 20 25 30 Arg Val Pro Gln Tyr Gln Arg Trp His Phe Ala His Cys Gln Arg Thr 35 40 45 Gly Ile Thr Thr Arg Phe Met Leu Leu Pro Pro Arg Ile Pro Arg Phe 50 55 60 Val Ala Thr Ser Thr Ala Leu Leu His Phe His Cys Ser Thr Ser Leu 65 70 75 80 Leu Tyr Gln Arg Leu Leu Arg Pro Ser Leu Met Gly Leu Gly Lys Trp 85 90 95 Pro Ser Leu Ile Asn Leu * 100 <210> 204 <211> 375 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(55702..56826) <400> 204 Met Arg Lys Arg Ile Leu Phe Ile Gly Pro Pro Leu Tyr Gly Leu Leu 1 5 10 15 Tyr Pro Leu Ile Ser Leu Ala Gln Ala Phe Arg Val Ile Gly His Asp 20 25 30 Val Val Ile Ser Ser Ala Gly Lys Phe Ala Asn Lys Ala Ala Glu Ala 35 40 45 Gly Leu Val Val Phe Asp Ala Val Pro Gly Leu Asp Ser Glu Ala Gly 50 55 60 Tyr Arg His Gln Glu Glu Leu Arg Lys Lys Ser Asn Ile Ile Gly His 65 70 75 80 Phe Ser Phe Phe Ser Asp Glu Met Ala Asp Asn Leu Ile Asp Phe Ala 85 90 95 Gly Lys Trp Arg Pro Asp Leu Ile Val Tyr Pro Pro Leu Asp Pro Ala 100 105 110 Gly Pro Leu Val Ala Ala Lys Tyr Arg Ile Pro Ser Val Met Leu Ala 115 120 125 Val Gly Phe Ala His Thr Ser Ala His Ile Gln Met Leu Asn Arg Ser 130 135 140 Leu Ser Asn Ala Tyr Arg Arg His Gly Val Ser Gly Pro Leu Cys Asp 145 150 155 160 Leu Ala Trp Ile Asp Val Ala Pro Pro Ser Met Ser Ile Leu Lys Asn 165 170 175 Ala Gly Glu Pro Val Ile Ser Met Arg Tyr Ile Pro Tyr Asn Gly Gly 180 185 190 Ala Val Lys Glu Thr Trp Trp Asp Arg Asp Ser Asp Arg Lys Arg Leu 195 200 205 Leu Ile Ser Leu Gly Thr Val Lys Pro Met Val Asp Gly Leu Glu Leu 210 215 220 Ile Ser Trp Val Met Asp Ser Ala Asn Glu Val Asp Ala Asp Ile Ile 225 230 235 240 Leu Gln Leu Ala Ile Asn Ala Arg Thr Gly Leu Arg Lys Leu Pro Ser 245 250 255 Asn Val Arg Leu Val Asp Trp Ile Pro Met Gly Val Phe Leu Asn Gly 260 265 270 Ala Asp Gly Phe Ile His His Gly Gly Ala Gly Asn Thr Leu Thr Ala 275 280 285 Leu Tyr Ser Gly Ile Pro Gln Ile Val Phe Gly Glu Gly Ala Asp Arg 290 295 300 Ser Val Asn Ala Glu Ile Val Ala Lys Arg Gly Cys Gly Ile Ile Pro 305 310 315 320 Asp Lys His Gly Leu Thr Ser Asp Leu Val Asn Arg Leu Leu Tyr Asp 325 330 335 Asp Ser Leu Arg Phe Cys Ser Asp Gln Val Ala Ala Glu Met Ala Glu 340 345 350 Gln Pro Ser Pro Ala Glu Ile Ala Glu Val Leu Met Arg Lys Leu Lys 355 360 365 Asn Asn Gly Lys Gln Leu * 370 <210> 205 <211> 92 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(56968..57243) <400> 205 Leu Glu Ser Leu Pro Glu Asn Asn Thr Ser Trp Val Ser Glu Gln Ile 1 5 10 15 Leu Ser Ala Pro Pro Lys Asp Val Asn Ile Arg Leu Gly Val Gly Ser 20 25 30 Leu Glu Gly Thr Thr Val Ser His Val Gln Arg Leu His His Ser Leu 35 40 45 Ile Ala Ala Gly Leu Glu Ser Asn Leu Thr Val Tyr Thr Gly Gly His 50 55 60 Asp Tyr Ala Trp Trp Arg Gly Ala Ile Ile Asp Glu Leu Ala Asn Tyr 65 70 75 80 Asn Cys Arg Lys Val Ser Asn Asn Asn Ser Val * 85 90 <210> 206 <211> 168 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(57245..57748) <400> 206 Met Ser Arg Gln Cys Thr His Tyr Gly Arg Trp Pro Gln His Gly Phe 1 5 10 15 Thr Ser Leu Lys Lys Leu Arg Pro Gln Ser Val Thr Ser Arg Ile Gln 20 25 30 Pro Gly Ser Asp Val Ile Val Cys Ala Glu Met Asp Glu Gln Trp Gly 35 40 45 Tyr Val Gly Ala Lys Ser Arg Gln Arg Trp Leu Phe Tyr Ala Tyr Asp 50 55 60 Arg Ile Arg Arg Thr Val Val Ala His Val Phe Gly Glu Arg Thr Leu 65 70 75 80 Ala Thr Leu Glu Arg Leu Leu Ser Leu Leu Ser Ala Phe Glu Val Val 85 90 95 Val Trp Met Thr Asp Gly Trp Pro Leu Tyr Glu Ser Arg Leu Lys Gly 100 105 110 Lys Leu His Val Ile Ser Lys Arg Tyr Thr Gln Arg Ile Glu Arg His 115 120 125 Asn Leu Asn Leu Arg Gln His Leu Ala Arg Leu Gly Arg Lys Ser Leu 130 135 140 Ser Phe Ser Lys Ser Val Glu Leu His Asp Lys Val Ile Gly His Tyr 145 150 155 160 Leu Asn Ile Lys His Tyr Gln * 165 <210> 207 <211> 92 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(57667..57942) <400> 207 Val Ala Ser Ile Ser Ile Arg Cys Pro Ser Cys Ser Ala Thr Glu Gly 1 5 10 15 Val Val Arg Asn Gly Lys Ser Thr Ala Gly His Gln Arg Tyr Leu Cys 20 25 30 Ser Pro Cys Arg Lys Thr Trp Gln Leu Gln Phe Thr Tyr Thr Ala Ser 35 40 45 Gln Pro Gly Lys His Gln Lys Ile Ile Asp Met Ala Met Asn Gly Val 50 55 60 Gly Cys Arg Ala Ser Ala Arg Ile Met Gly Val Gly Leu Asn Thr Val 65 70 75 80 Leu Arg His Leu Lys Asn Ser Gly Arg Ser Arg * 85 90 <210> 208 <211> 153 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(58180..58638) <400> 208 Met Lys Ile Tyr Trp Thr Arg Lys Arg Ile Pro Glu Leu Ser Ala Leu 1 5 10 15 Pro Pro Ser Leu Arg Lys Lys Asn Phe Thr Asp Ala Tyr Asn Ala Ala 20 25 30 Ser Ser His Ile Glu Tyr Trp Ile Gly Ala Gly Val Ser Phe Ile Ser 35 40 45 Met Met Ile Leu Ser Arg Val Tyr Asp Phe Leu Leu Pro Ala Gln Asp 50 55 60 Thr Phe Pro Gly Asp Ile Ile Arg Ser Leu Cys Val Val Cys Pro Ser 65 70 75 80 Ile Leu Ile Trp Phe Gln Phe Ser Val Tyr Val Met Arg Lys Tyr Tyr 85 90 95 Arg His Ile Leu Val Arg Gly Lys Glu Thr Glu Thr Ile Ser Glu Arg 100 105 110 Leu Ile Arg Glu Ala Asp Thr Arg Glu Tyr Glu Leu Trp Arg Pro Val 115 120 125 Arg Arg Phe Phe Ser Ile Val Phe Leu Ile Val Leu Leu Gly Cys Ile 130 135 140 His Ser Leu Ile Thr Thr Ile Lys * 145 150 <210> 209 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(58703..58894) <400> 209 Met Thr Thr Ser Pro Phe Ile Leu Glu Phe His Asp Asn Asp Arg Asp 1 5 10 15 Asn His Tyr Gln Leu Ile Val Ser Val Ile Leu Thr Tyr Ile Thr Leu 20 25 30 Ser Trp Phe Asn Gln Val Ile Asp Leu Met Lys Arg Val Cys Leu Trp 35 40 45 Met Tyr Cys Val Tyr Val Leu Pro Gly Ile Cys Ser Tyr Ile Asn * 50 55 60 <210> 210 <211> 170 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(59096..59605) <400> 210 Val Gln Ile Thr Glu Ala Leu Ile Ser Glu Pro Gly Glu Ile Arg Arg 1 5 10 15 Phe Val Gln Gln Ala Val Asp His Trp Pro Asn Leu Leu Ala Phe His 20 25 30 Phe Thr Leu Tyr Ser Ala Glu Gly Ile Tyr Gly Gln Gln Ile Gln Thr 35 40 45 Phe Cys Ser Ser Phe His Arg Arg Val His Glu Arg Ile Thr Glu His 50 55 60 Asn His Thr Val Ser Pro Ser Ala Pro Val Val Leu Arg Trp Leu Arg 65 70 75 80 Glu Gln His Glu Gly Ala Gln Ile Arg Cys Leu Leu Leu Leu Ser Gln 85 90 95 Thr Ser Ile Cys His Pro Arg Val Gly Val Met Ala Asp Glu Glu Cys 100 105 110 Ala Gln Leu Val Asp Leu Leu Gln Gln Thr Trp Ser Val Ile Ser Ala 115 120 125 Gly Gly Gln Cys Arg Val Glu Arg Cys Phe Arg Val Ala Arg Pro Gly 130 135 140 Ser Ser Gly Gln Tyr Val Ala Leu Lys Thr Ala Val Gln Ser Phe Met 145 150 155 160 Ser Gln Val Ile Ala Thr Ile Ile Arg * 165 <210> 211 <211> 208 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(59694..60317) <400> 211 Met Arg Thr Arg Ile Asp Tyr Leu Ala Asp Lys Tyr Cys Phe Thr Glu 1 5 10 15 Arg Asn Glu Ser Pro Arg Leu Arg Arg Gln Trp Gln Asp Val Leu Glu 20 25 30 Glu Cys Arg Gln Thr Glu Ala Gly Pro Glu Glu Arg Leu Arg Ile Ala 35 40 45 Leu Leu Asn Val Asp Tyr Val Thr Ser Phe Glu Leu Pro Phe Arg Leu 50 55 60 Leu Leu Thr Arg Thr Pro Gln Leu Ile Ala Ala Leu Arg Glu Glu Trp 65 70 75 80 Gly Ile Ser Gln Lys Asn Val Val Phe Asn Asp Lys Arg Phe Gly Cys 85 90 95 Val Tyr Ser Leu Lys Ala Ser Leu Ser Gly Val Pro Asp Thr Tyr Arg 100 105 110 Tyr His Leu Ser His Arg Ile Arg Arg Val Val Gly Asn Glu Asn Thr 115 120 125 Ser Leu Pro Tyr Gln Gln Val Ala Arg Glu Val Lys Ala Pro Arg Glu 130 135 140 Arg Leu Lys Tyr Ala Leu Glu Ala Gly Leu Leu Val Thr Ala Leu Asp 145 150 155 160 Gly Leu Phe Arg Phe Gly Ser Gln Arg Ile Ala Ala Asp Val Leu Arg 165 170 175 Leu Arg Lys Ala Gly Met Pro Val Val Thr Thr Thr Val Glu Val His 180 185 190 Asp Asn Leu Thr Gly Thr Thr Arg Lys Val Pro Ala Tyr His Leu * 195 200 205 <210> 212 <211> 78 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(60413..60646) <400> 212 Met Ala Arg Ser Asp Tyr Asp Ile Ile Asn Leu Ser Leu Glu His Glu 1 5 10 15 Leu Asn Glu Trp Leu Ala Glu Arg Gly Tyr Ala Gly Leu Val Asp Asn 20 25 30 Arg Asn Arg Leu Ala Glu Val Val Thr Arg Lys Leu Gln Asp Ser Phe 35 40 45 Tyr Ile Asn Val Ser Arg Asp Ala Leu Asn Thr Ala Tyr Ser Glu His 50 55 60 Pro Glu Trp Phe Ser Gly Leu Val Ser Gly Asp Glu Asn * 65 70 75 <210> 213 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(60657..60872) <400> 213 Met Leu Leu Ser Gly Ser Val Ile Ala Gly Arg Asp Phe Val Leu Phe 1 5 10 15 Cys Phe Phe Pro Gly Phe Gly Phe Glu Phe Ser Gln Lys Val Val His 20 25 30 Arg Ser His Ala Gly Met Arg Ile Ala Val Leu His Lys His His Pro 35 40 45 Gly Phe Leu Asn Thr Gly Gln Gly Asp Lys Arg Thr Met Ile Val Phe 50 55 60 Val Ser Leu Ile Asp Phe Arg * 65 70 <210> 214 <211> 296 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(61484..62371) <400> 214 Met Pro Leu Leu Asp Lys Leu His Glu Gln Tyr Gly Val Gly Pro Val 1 5 10 15 Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln Gln 20 25 30 Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln Arg Asp Asp 35 40 45 Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln Val 50 55 60 Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile Arg 65 70 75 80 Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu Ala 85 90 95 Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Val Ser Arg Lys Ala 100 105 110 Val Ser Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg Pro 115 120 125 Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln Gly 130 135 140 Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Cys Ile Val 145 150 155 160 Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp Ala 165 170 175 Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Val His His 180 185 190 Ser Asp Lys Gly Ser Gln Tyr Ile Ser Leu Ala Tyr Thr Glu Arg Leu 195 200 205 Lys Glu Ala Lys Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser Tyr 210 215 220 Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu Val 225 230 235 240 Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala Thr 245 250 255 Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg Leu 260 265 270 Gly His Ile Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser Ile 275 280 285 Arg Asn Asp Asp Leu Ala Ala * 290 295 <210> 215 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(62371..62697) <400> 215 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Val 1 5 10 15 Arg Met Val Leu Glu Ser Gln Gly Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Ser Gly Asp Gly Gly 50 55 60 Leu Thr Thr Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 216 <211> 245 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(63190..63924) <400> 216 Met Ser Thr Leu Gln Asn Arg Leu Val Asp His Gly Tyr Val Thr Thr 1 5 10 15 Arg Val Leu Ala Pro Ser Gln Asp Leu Lys Ser Gly Ile Leu Arg Leu 20 25 30 Val Ile Ile Pro Gly Val Val Arg His Val Arg Leu Thr Pro Asp Ser 35 40 45 Asp Asp Tyr Ile Gln Leu Tyr Ser Ser Phe Pro Ala His Glu Gly Ser 50 55 60 Leu Leu Asp Leu Arg Asp Ile Glu Gln Gly Leu Asp Leu Gly Asn Ser 65 70 75 80 Arg Ile Gln Gly Gln His Thr Glu Leu Asn Ala Thr Ser Gly Asn Leu 85 90 95 Ser Thr Gln Asn Ala Gln Leu Ser Ala Asp Thr Leu Ser Ala Arg Thr 100 105 110 Ala Gly Gln Phe Ser Ser Asn Gly Gly Thr Ile Asn Ala Asp Thr Leu 115 120 125 Gln Ile Ser Ala Gln Ser Leu Ser Asn Arg Lys Gly Ser Leu Ile Gln 130 135 140 Thr Gly Thr Gly Asp Phe Ser Leu Ser Leu Pro Gly Ser Val Asp Asn 145 150 155 160 Arg Glu Gly Leu Leu Ala Ala Asn Gly Ala Val Arg Leu Asp Ala Leu 165 170 175 Ser Leu Asp Asn Arg Lys Gly Lys Val Gln Ala Glu Gln Ser Pro Ser 180 185 190 Leu Gln Lys Ser Pro Pro Thr Phe Leu Lys Pro Phe Val Ala Gly Val 195 200 205 Cys Ala Ala Leu Leu Ala Val Ser Val Ala Ile Pro Gly Trp Gln Phe 210 215 220 Leu Thr Gln Pro Ser Pro Glu Glu Gln His Phe Thr Trp Gly Asn Gly 225 230 235 240 Cys Lys Lys Gln * <210> 217 <211> 172 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(64165..64680) <400> 217 Met Val Thr Ile Cys Val Asp Gly Glu Asn Lys Thr His Lys Ile Thr 1 5 10 15 Asp Trp Thr Leu Trp Ala Gly Asn Asp Asp Arg Glu Val Met Leu Thr 20 25 30 Cys His Phe Arg Ser Gly Arg Lys Tyr Thr Arg Pro Leu Ser Val Cys 35 40 45 Gln Ile Thr Pro Thr Val Asn Leu Arg Asn Val Phe Leu Glu Arg Lys 50 55 60 Gly Asn Ala Val Thr Ser Arg Ala Glu Leu Val Ile Ile Tyr Gly Asp 65 70 75 80 Lys Tyr Ala Ala Val Tyr Tyr Arg Glu Gly Glu Arg Pro Tyr Ile Met 85 90 95 Lys Thr Thr Gly Leu Asp Phe Gln Gln Cys Ser Ala Phe Thr Glu His 100 105 110 Ala Val Phe Asn Tyr Leu Cys Arg Val Ala Asn Glu Arg Ile Phe Tyr 115 120 125 Ala Arg Gly Asn Asn Arg Asn Ile Asp Glu Asn Ile Leu Arg Gln Ile 130 135 140 Lys Lys Ile Val Pro His Pro Asp Thr Ala Leu His Ala Tyr Cys Ser 145 150 155 160 Gly Gln Ser Lys Asn Val Ile Arg His Gly Val * 165 170 <210> 218 <211> 646 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(64908..66845) <400> 218 Met Ala Arg Leu Gly Ser Thr Glu Asn Arg Gln Gln Phe Phe Ser Thr 1 5 10 15 Ser Ile Ser Arg Ser Glu Glu Val Leu Pro Asp Ser Pro Ser Ala Asn 20 25 30 Ala Ile Asp Asp Val Leu Gln Gln Val Lys Lys His Leu Asn Ala Ile 35 40 45 Asn Gln Val Ala Ser Leu Lys Ala Glu Ile Asn Glu Leu Asn Ile Glu 50 55 60 Tyr Lys Tyr Leu Gln Gln Trp Gln Ser Gln Asn Leu Arg Pro Glu Glu 65 70 75 80 Leu Phe Ser His Lys Tyr Arg Phe Ser Ser Gln Lys Thr Thr Asp Leu 85 90 95 Met Ala Tyr Ile His Tyr Leu Ser Asp Arg Arg Ile Gly Phe Arg Asn 100 105 110 Arg Ile Asp Leu Leu Leu Asn Phe Met Ile Leu Lys Val Lys Pro Leu 115 120 125 Met Ile Pro Glu Arg Arg Leu Ala Leu Phe Thr Ser Leu Gln Leu Ser 130 135 140 Tyr Tyr Glu Lys Asn Ile Arg Glu Lys Gln Ile Ser Leu Asn Glu Tyr 145 150 155 160 Glu Glu Ala Phe Lys Lys Ser Asp Phe Lys Ile Leu Leu Gly Arg Leu 165 170 175 Thr Ser Trp Ser Met Leu Tyr Leu Lys Gln His Leu Arg Arg Asn Val 180 185 190 Ser Thr Arg Ser Ser Phe Ser Ala Glu Thr Tyr Arg Asp Glu Phe Asp 195 200 205 Arg Phe Ile Lys Arg Phe Pro Ile Ile Gly Ser Ser Thr His Ser Ile 210 215 220 Ile Asn Ser Ile Gly Lys Gly Ala Leu Leu Asp Tyr Val Ile Ile Asp 225 230 235 240 Glu Ala Ser Gln Gln Asp Ile Val Pro Gly Ile Leu Gly Leu Gly Cys 245 250 255 Ala Arg Asn Val Ile Val Val Gly Asp Arg Lys Gln Leu Pro His Val 260 265 270 Pro Val Leu Leu Pro Asn Ser Pro Ser Pro Pro Ala Glu Tyr Tyr Asn 275 280 285 Cys Glu Lys Tyr Ser Leu Leu Asp Ser Val Cys Met Leu Phe Arg Asn 290 295 300 Met Val Pro Val Thr Leu Leu Lys Glu His Tyr Arg Cys His Pro Lys 305 310 315 320 Ile Ile Gln Phe Cys Asn Lys Gln Phe Tyr Asp Asn Ala Leu Ile Pro 325 330 335 Leu Thr Val Asp Ser Gly Glu Ala Ser Leu Ser Leu Val Ile Thr Ala 340 345 350 Lys Gly Asn His Thr Arg Asn Phe Ser Asn Leu Arg Glu Leu Glu Ser 355 360 365 Leu Glu Gly His Tyr Trp Asp Glu Glu Ser Ser Arg Gly Tyr Ile Ala 370 375 380 Pro Tyr Asn Ala Gln Val Asn Leu Ala Glu Lys Val Leu Pro Ala Asp 385 390 395 400 Phe Val Lys Ser Thr Val His Lys Phe Gln Gly Arg Glu Cys Asp Glu 405 410 415 Ile Val Phe Ser Thr Val Leu Asp Lys Lys Arg Ser Ser Gln His Ser 420 425 430 Arg Asn Ile Ala Phe Val Asp Asn Pro Glu Leu Val Asn Val Ala Val 435 440 445 Ser Arg Ala Arg Asn Lys Phe Thr Leu Val Thr Gly Asn Asp Val Phe 450 455 460 Glu Arg His Ala Gly His Ile Ala Ala Leu Ile Arg Tyr Ile Lys Tyr 465 470 475 480 Tyr Ala Asp Asp Gly Glu Ile Phe Glu Ser Pro Val Ile Ser Ala Phe 485 490 495 Asp Leu Leu Tyr Ser Glu Tyr Asp Lys Ser Leu Glu Arg Leu Asn Ser 500 505 510 Arg Leu Asn Ser Asn Asp Ser His Phe Lys Ser Glu Gln Ile Val Ala 515 520 525 Cys Leu Leu Arg Asp Ile Leu Ser Gln Asp Ser Tyr Arg Ser Met Met 530 535 540 Phe His Ser Gln Ile Ala Leu Asn Gln Leu Val Leu Leu Glu Arg Gly 545 550 555 560 Asp Phe Thr His Arg Glu Gln Leu Phe Met Arg Asn Arg Ala Ser Cys 565 570 575 Asp Phe Val Val Tyr Tyr Lys Val Gly Lys Thr Pro Leu Gly Val Ile 580 585 590 Glu Val Asp Gly Gly Tyr His Leu Thr Ser Val Gln Ala Glu Arg Asp 595 600 605 Glu Leu Lys Asn Ser Ile Leu Lys Lys Cys Gly Leu Pro Leu Leu Arg 610 615 620 Leu Arg Thr Ile Asp Ser Asp Ile Glu Gly Lys Leu Gly Ala Phe Leu 625 630 635 640 Ser Gly Leu Thr Gly * 645 <210> 219 <211> 47 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(66889..67029) <400> 219 Leu Val Met Cys His Thr Gln Leu Tyr Glu Pro His Gly His Arg Leu 1 5 10 15 Leu Cys Phe Gly Tyr Ile Asn Val Arg Ile Pro Asp Thr Tyr Lys Asn 20 25 30 Lys Cys Tyr Cys Ser Lys Leu Thr Gly Asn Val Ser Val Glu * 35 40 45 <210> 220 <211> 411 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(67346..68578) <400> 220 Met Ser Asp Thr Leu Leu Thr Glu Lys Ile Leu Thr Gly Glu Asn Val 1 5 10 15 Leu Arg Ala Ala Ile Ala Arg Ile Glu Trp Ile Phe Glu Thr Phe Pro 20 25 30 Ser Val Cys Leu Ser Phe Ser Gly Gly Lys Asp Ser Thr Val Leu Phe 35 40 45 His Leu Val Ala Glu Val Ala Arg Arg Arg Lys Arg His Phe Ser Val 50 55 60 Leu Phe Ile Asp Trp Glu Ala Gln Tyr Arg Cys Thr Ile Glu His Ile 65 70 75 80 Gln Lys Met Arg Glu Met Tyr His Asp Val Thr Glu Thr Phe Tyr Trp 85 90 95 Val Ala Leu Pro Leu Thr Thr Val Asn Gly Val Ser Gln Phe Gln Pro 100 105 110 Glu Trp Ile Cys Trp Glu Pro Gly Val Thr Trp Val Arg Gln Pro Pro 115 120 125 Glu Glu Ala Ile Thr Asp Met Thr Tyr Phe Pro Phe Phe Arg Tyr Ala 130 135 140 Met Thr Phe Glu Glu Phe Val Pro Ala Phe Ser Ser Trp Phe Ala Gly 145 150 155 160 Asn Arg Cys Gly Val Ala Val Leu Thr Gly Val Arg Ala Asp Glu Ser 165 170 175 Leu Asn Arg Phe Met Gly Leu Val Ser Gln Arg Lys Leu Arg Tyr Ala 180 185 190 Asp Asp Lys Pro Trp Thr Thr Ala Ser Pro Glu Gly Phe Tyr Tyr Thr 195 200 205 Met Tyr Pro Leu Tyr Asp Trp Lys Ala Arg Asp Ile Trp Ile Tyr Asn 210 215 220 Ala Arg Ala Cys Ala Ile Tyr Asn Pro Leu Tyr Asp Leu Met Tyr Arg 225 230 235 240 Ala Asp Val Pro Leu Arg Asn Met Arg Val Cys Glu Pro Phe Gly Pro 245 250 255 Glu Gln Arg Lys Gly Leu Trp Leu Tyr His Val Leu Glu Pro Glu Thr 260 265 270 Trp Ala Arg Met Cys Glu Arg Val Ser Gly Ala Ala Ser Gly Ala Leu 275 280 285 Tyr Ala Asn Glu Ser Gly Ala Tyr Phe Ala Leu Arg Lys Arg Ile Ser 290 295 300 Lys Pro Ala His His Thr Trp Arg Ser Tyr Ala Met Phe Leu Leu Asp 305 310 315 320 Val Met Pro Glu Arg Thr Ala Glu His Tyr Arg Asn Lys Ile Ala Val 325 330 335 Tyr Leu Arg Trp Tyr Gln Thr Arg Gly Phe Pro Asp Asp Ile Pro Asp 340 345 350 Glu Gln Glu Asn Asp Leu Gly Ser Arg Asp Ile Pro Ser Trp Arg Arg 355 360 365 Ile Cys Lys Thr Leu Ile Lys Asn Asp Phe Trp Cys Arg Pro Leu Ser 370 375 380 Phe Ser Pro Asn Lys Pro Arg His Tyr Glu Arg Tyr Leu Gln Arg Met 385 390 395 400 Lys Glu Arg Arg Lys Glu Trp Gly Ile Leu * 405 410 <210> 221 <211> 213 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(68563..69201) <400> 221 Met Gly Asp Ser Val Thr Pro Glu Ile Ile Gly Asn Met Ile Arg Gln 1 5 10 15 Tyr Phe Ser Gln Glu Arg Pro Glu Glu Glu Thr Ile Gln Ala Leu Asn 20 25 30 His Leu Arg Arg Val Leu His Glu Val Ser Pro Phe Ala His Glu Pro 35 40 45 Val Asp Cys Val Leu Trp Val Lys Ala Asp Glu Val Val Ala Asn Asp 50 55 60 Tyr Asn Pro Asn Val Met Ala Pro Gly Glu Lys Lys Leu Leu Lys Gln 65 70 75 80 Ser Leu Glu Lys Asp Gly Phe Thr Gln Pro Val Val Val Ser Glu Glu 85 90 95 Lys Asn His Tyr Leu Val Val Asp Gly Phe His Arg Gln Val Leu Gly 100 105 110 Arg Glu Ala Gly Thr Gly Lys Arg Leu Lys Gly Trp Leu Pro Val Val 115 120 125 Cys Ile Asn Pro Glu Arg Lys Gly Gln Ala Ser Arg Ile Ala Ala Thr 130 135 140 Ile Arg His Asn Arg Ala Arg Gly Lys His Gln Ile Thr Ser Met Ser 145 150 155 160 Asp Ile Val Arg Asp Leu Ser Arg Leu Gly Trp Thr Asn Glu Arg Ile 165 170 175 Gly Thr Glu Leu Gly Met Asp Gln Asp Glu Val Leu Arg Leu Lys Gln 180 185 190 Ile Ser Gly Leu Thr Glu Leu Phe Gln Glu Glu Asp Phe Ser Pro Ala 195 200 205 Trp Thr Val Arg * 210 <210> 222 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(69280..69549) <400> 222 Met Val Ala Gln Lys Leu Glu Ala Ala Gly Cys Trp Arg Arg Ala Ser 1 5 10 15 Asp Arg Trp Leu Phe Val Met Gly Asn Val Glu Cys Thr Glu Ala Gln 20 25 30 Arg Glu Trp Leu Leu Leu Arg Arg Asn Tyr Cys Leu Ala Gln Ile Ser 35 40 45 Ser Pro Pro Leu Pro Glu Thr Leu Asp Ile Ser Glu Val Ala Lys Ala 50 55 60 Ala Asp Ala Thr Leu Arg Arg Met Gly Ile Ala Thr Pro Ser Gly Glu 65 70 75 80 Val Phe Arg Lys Gly Thr Pro Val Cys * 85 <210> 223 <211> 215 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(69570..70214) <400> 223 Met Met Lys Gln Gly Met Ala Asn Ser Ile Ser Met Thr Trp Gln Leu 1 5 10 15 Leu Cys Asp Glu His Gly Phe Thr Arg Glu His Tyr Asn Gln Leu Lys 20 25 30 Lys Phe Ser Pro Glu Thr Leu Arg Glu Ile Ile Ala Glu Ile Ala Ser 35 40 45 Cys His Pro Ser Thr Ser Val Leu Leu Arg Asn Lys Trp Leu Thr Pro 50 55 60 Pro Glu Asp Ile Leu Glu Gln Ile Thr Arg Glu Tyr Glu Arg Arg Ile 65 70 75 80 Gln Asn Cys Pro Pro Phe Arg Ser Glu Lys Glu Ala Glu Ser Trp Leu 85 90 95 Asn Glu Leu Ser Phe Ala Val Ile Ala Pro Leu Tyr Arg Val Ala Pro 100 105 110 Glu Gln Thr Glu Gln Val Glu Ser Phe Val Leu Gln Leu Ile Ala Glu 115 120 125 Gln Glu Arg Val Trp Glu Leu Ile Leu Thr Asn Asp Gly Tyr Ser Trp 130 135 140 His Cys Ala Leu Tyr Asp Ile Leu Phe His Leu Val Leu Arg Asn Met 145 150 155 160 Glu Asp Gln Pro Glu His Gln Lys Gln Arg Ile Thr Lys Ile Phe Tyr 165 170 175 Glu Pro Asp Ala Arg Leu Val Ala Glu Glu Ile Lys Phe Arg Ile Gln 180 185 190 Ser Leu Tyr Asp Asp Glu Gln Lys Arg Ala Leu Ser Glu Leu Val Asn 195 200 205 Asp Phe Thr Ser Lys Glu * 210 <210> 224 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(70262..70417) <400> 224 Met Lys Val Asn Gly Val Thr Thr Ser Lys Tyr Glu Gly Trp Arg Gly 1 5 10 15 Thr Phe Gln Leu Tyr Arg Tyr Lys Thr Val Val Leu Val His Pro Lys 20 25 30 Gly Tyr Leu Ala Gly Glu Met Ile His Arg Gln Ala Leu Thr Ser Ser 35 40 45 Cys Gln Asp * 50 <210> 225 <211> 167 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(70530..71030) <400> 225 Met Asn Arg Glu Ile Gln Gln Arg Leu Gln Trp Val Lys Leu Tyr Glu 1 5 10 15 Thr Ser Gly Asp Ala Gly Phe Val Cys Arg Arg Cys Gly Ile Ser Arg 20 25 30 Pro Thr Leu Arg Lys Met Val Ala Gln Ile Ser Gly Ser Gly His Arg 35 40 45 Trp Ser Gly Lys Pro Gln Pro Ser Pro Gln Ala Phe Thr Ile Asn Glu 50 55 60 Asn Arg His Leu Arg Ser Arg Ser Asp Ser Gly Val Thr Phe Ser Ala 65 70 75 80 Lys Ser Gly Gly Lys Thr Tyr Ser Lys Arg Val Lys Thr Thr Ser Phe 85 90 95 Asn Leu Thr Gly Asn Ser Asn Asn Pro Gln Ser Pro Phe Pro Glu Ser 100 105 110 Gly Leu Asn Arg Pro Gly Phe Pro Gly Glu Cys Phe Ile Cys Glu Leu 115 120 125 Arg Leu Pro Asp His Arg Phe Arg Trp Lys His Asn Lys Leu Phe Leu 130 135 140 Leu Leu Pro Glu Glu Tyr Gly Pro Ala Phe Pro Ala Ile Val Asp Cys 145 150 155 160 Tyr Thr Ser Pro Pro Thr * 165 <210> 226 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(70978..71199) <400> 226 Met Ala Gln Pro Phe Gln Gln Ser Ser Ile Val Ile Pro Val His Pro 1 5 10 15 Arg Glu Cys Gly Gln Phe His Phe Cys Thr Val Phe Pro Ala Leu Thr 20 25 30 Val Tyr Tyr Leu Arg Phe Val Lys Thr Ile Asp Ala Leu Arg His Arg 35 40 45 Val Val Ser Lys Arg Lys Leu Thr Ala Val Cys Ser His Gln Thr Lys 50 55 60 Ile Gly Asn Leu Asp Ala His Leu Ile * 65 70 <210> 227 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(71214..71639) <400> 227 Met Glu Leu Gln Asp Trp Arg Lys Glu Pro Arg Lys Asn Tyr Ser Asn 1 5 10 15 Glu Phe Lys Leu Arg Met Val Glu Leu Ala Ser Gln Pro Gly Ala Ser 20 25 30 Val Ala Arg Ile Ala Arg Glu His Asp Ile Asn Asp Asn Leu Leu Phe 35 40 45 Lys Trp Leu Arg Leu Trp Gln Asn Glu Gly Arg Ile Ser Arg Arg Leu 50 55 60 Gln Val Thr Thr Ser Ser Asp Thr Gly Val Glu Leu Leu Pro Val Glu 65 70 75 80 Ile Thr Pro Asp Glu Gln Lys Glu Pro Val Ala Ala Ile Ala Pro Ser 85 90 95 Leu Ser Thr Ser Thr Gln Thr Ser Val Ser Ala Gly Ser Cys Lys Val 100 105 110 Glu Phe Arg His Gly Asn Met Thr Leu Glu Asn Pro Ser Pro Glu Leu 115 120 125 Leu Thr Leu Leu Ile Arg Glu Leu Thr Gly Arg Gly Arg * 130 135 140 <210> 228 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(71939..72121) <400> 228 Met Tyr Asn Cys Gly Glu Ser Tyr Ser Glu Tyr Asp Ile Ser Leu Ser 1 5 10 15 Asp Asp Glu Asn Tyr Asp Asp Asp Tyr Tyr Arg Glu Arg Pro Cys Pro 20 25 30 Gly Glu Val Phe Gly Tyr Asp Asn Thr Glu Asp Asn Asp Glu Ala Ala 35 40 45 Ser Asp Tyr Ala Leu Lys Ile Asn Glu Asn Ser Asp * 50 55 60 <210> 229 <211> 291 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(72450..73322) <400> 229 Met Asn Pro Ser Asp Ala Ile Glu Ala Ile Glu Lys Pro Leu Ser Ser 1 5 10 15 Leu Pro Tyr Ser Leu Ser Arg His Ile Leu Glu His Leu Arg Lys Leu 20 25 30 Thr Ser His Glu Pro Val Ile Gly Ile Met Gly Lys Ser Gly Ala Gly 35 40 45 Lys Ser Ser Leu Cys Asn Ala Leu Phe Gln Gly Glu Val Thr Pro Val 50 55 60 Ser Asp Val His Ala Gly Thr Arg Glu Val Arg Arg Phe Arg Leu Ser 65 70 75 80 Gly His Gly His Ser Met Val Ile Thr Asp Leu Pro Gly Val Gly Glu 85 90 95 Ser Arg Asp Arg Asp Ala Glu Tyr Glu Ala Leu Tyr Arg Asp Ile Leu 100 105 110 Pro Glu Leu Asp Leu Val Leu Trp Leu Ile Lys Ala Asp Asp Arg Ala 115 120 125 Leu Ser Val Asp Glu Tyr Phe Trp Arg His Ile Leu His Arg Gly His 130 135 140 Gln Gln Val Leu Phe Val Val Thr Gln Ala Asp Lys Thr Glu Pro Cys 145 150 155 160 His Glu Trp Asp Met Ala Gly Ile Gln Pro Ser Pro Ala Gln Glu Gln 165 170 175 Asn Ile Arg Glu Lys Thr Asp Ala Val Phe Arg Leu Phe Arg Pro Val 180 185 190 His Pro Val Val Ala Val Ser Ala Arg Thr Gly Trp Glu Leu Asp Thr 195 200 205 Leu Val Ser Ala Leu Met Thr Ala Leu Pro Asp His Ala Ala Ser Pro 210 215 220 Leu Met Thr Arg Leu Gln Asp Glu Leu Cys Thr Glu Ser Val Trp Gly 225 230 235 240 Gln Ala Arg Glu Gln Phe Thr Gly Ala Val Asp Arg Ile Phe Asp Thr 245 250 255 Val Glu Ser Val Cys Val Ala Ser Val Ala Arg Thr Val Leu Arg Ala 260 265 270 Val Arg Asp Thr Val Val Ser Val Ala Arg Ala Val Trp Asn Trp Ile 275 280 285 Phe Phe * 290 <210> 230 <211> 950 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(73694..76543) <400> 230 Met Lys Arg His Leu Asn Thr Ser Tyr Arg Leu Val Trp Asn His Ile 1 5 10 15 Thr Gly Thr Leu Val Val Ala Ser Glu Leu Ala Arg Ser Arg Gly Lys 20 25 30 Arg Ala Gly Val Ala Val Ala Leu Ser Leu Ala Ala Val Thr Ser Val 35 40 45 Pro Ala Leu Ala Ala Asp Lys Val Val Gln Ala Gly Glu Thr Val Asn 50 55 60 Asp Gly Thr Leu Thr Asn His Asp Asn Gln Ile Val Phe Gly Thr Ala 65 70 75 80 Asn Gly Met Thr Ile Ser Thr Gly Leu Glu Leu Gly Pro Asp Ser Glu 85 90 95 Glu Asn Thr Gly Gly Gln Trp Ile Gln Asn Gly Gly Ile Ala Gly Asn 100 105 110 Thr Thr Val Thr Thr Asn Gly Arg Gln Val Val Leu Glu Gly Gly Thr 115 120 125 Ala Ser Asp Thr Val Ile Arg Asp Gly Gly Gly Gln Ser Leu Asn Gly 130 135 140 Leu Ala Val Asn Thr Thr Leu Asn Asn Arg Gly Glu Gln Trp Val His 145 150 155 160 Glu Gly Gly Val Ala Thr Gly Thr Ile Ile Asn Arg Asp Gly Tyr Gln 165 170 175 Ser Val Lys Ser Gly Gly Leu Ala Thr Gly Thr Ile Ile Asn Thr Gly 180 185 190 Ala Glu Gly Gly Pro Asp Ser Asp Asn Ser Tyr Thr Gly Gln Lys Val 195 200 205 Gln Gly Thr Ala Glu Ser Thr Thr Ile Asn Lys Asn Gly Arg Gln Ile 210 215 220 Ile Leu Phe Ser Gly Leu Ala Arg Asp Thr Leu Ile Tyr Ala Gly Gly 225 230 235 240 Asp Gln Ser Val His Gly Arg Ala Leu Asn Thr Thr Leu Asn Gly Gly 245 250 255 Tyr Gln Tyr Val His Arg Asp Gly Leu Ala Leu Asn Thr Val Ile Asn 260 265 270 Glu Gly Gly Trp Gln Val Val Lys Ala Gly Gly Ala Ala Gly Asn Thr 275 280 285 Thr Ile Asn Gln Asn Gly Glu Leu Arg Val His Ala Gly Gly Glu Ala 290 295 300 Thr Ala Val Thr Gln Asn Thr Gly Gly Ala Leu Val Thr Ser Thr Ala 305 310 315 320 Ala Thr Val Ile Gly Thr Asn Arg Leu Gly Asn Phe Thr Val Glu Asn 325 330 335 Gly Lys Ala Asp Gly Val Val Leu Glu Ser Gly Gly Arg Leu Asp Val 340 345 350 Leu Glu Ser His Ser Ala Gln Asn Thr Leu Val Asp Asp Gly Gly Thr 355 360 365 Leu Ala Val Ser Ala Gly Gly Lys Ala Thr Ser Val Thr Ile Thr Ser 370 375 380 Gly Gly Ala Leu Ile Ala Asp Ser Gly Ala Thr Val Glu Gly Thr Asn 385 390 395 400 Ala Ser Gly Lys Phe Ser Ile Asp Gly Thr Ser Gly Gln Ala Ser Gly 405 410 415 Leu Leu Leu Glu Asn Gly Gly Ser Phe Thr Val Asn Ala Gly Gly Gln 420 425 430 Ala Gly Asn Thr Thr Val Gly His Arg Gly Thr Leu Thr Leu Ala Ala 435 440 445 Gly Gly Ser Leu Ser Gly Arg Thr Gln Leu Ser Lys Gly Ala Ser Met 450 455 460 Val Leu Asn Gly Asp Val Val Ser Thr Gly Asp Ile Val Asn Ala Gly 465 470 475 480 Glu Ile Arg Phe Asp Asn Gln Thr Thr Pro Asn Ala Ala Leu Ser Arg 485 490 495 Ala Val Ala Lys Ser Asn Ser Pro Val Thr Phe His Lys Leu Thr Thr 500 505 510 Thr Asn Leu Thr Gly Gln Gly Gly Thr Ile Asn Met Arg Val Arg Leu 515 520 525 Asp Gly Ser Asn Ala Ser Asp Gln Leu Val Ile Asn Gly Gly Gln Ala 530 535 540 Thr Gly Lys Thr Trp Leu Ala Phe Thr Asn Val Gly Asn Ser Asn Leu 545 550 555 560 Gly Val Ala Thr Thr Gly Gln Gly Ile Arg Val Val Asp Ala Gln Asn 565 570 575 Gly Ala Thr Thr Glu Glu Gly Ala Phe Ala Leu Ser Arg Pro Leu Gln 580 585 590 Ala Gly Ala Phe Asn Tyr Thr Leu Asn Arg Asp Ser Asp Glu Asp Trp 595 600 605 Tyr Leu Arg Ser Glu Asn Ala Tyr Arg Ala Glu Val Pro Leu Tyr Thr 610 615 620 Ser Met Leu Thr Gln Ala Met Asp Tyr Asp Arg Ile Leu Ala Gly Ser 625 630 635 640 Arg Ser His Gln Thr Gly Val Asn Gly Glu Asn Asn Ser Val Arg Leu 645 650 655 Ser Ile Gln Gly Gly His Leu Gly His Asp Asn Asn Gly Gly Ile Ala 660 665 670 Arg Gly Ala Thr Pro Glu Ser Ser Gly Ser Tyr Gly Phe Val Arg Leu 675 680 685 Glu Gly Asp Leu Leu Arg Thr Glu Val Ala Gly Met Ser Leu Thr Thr 690 695 700 Gly Val Tyr Gly Ala Ala Gly His Ser Ser Val Asp Val Lys Asp Asp 705 710 715 720 Asp Gly Ser Arg Ala Gly Thr Val Arg Asp Asp Ala Gly Ser Leu Gly 725 730 735 Gly Tyr Leu Asn Leu Val His Thr Ser Ser Gly Leu Trp Ala Asp Ile 740 745 750 Val Ala Gln Gly Thr Arg His Ser Met Lys Ala Ser Ser Asp Asn Asn 755 760 765 Asp Phe Arg Ala Arg Gly Trp Gly Trp Leu Gly Ser Leu Glu Thr Gly 770 775 780 Leu Pro Phe Ser Ile Thr Asp Asn Leu Met Leu Glu Pro Gln Leu Gln 785 790 795 800 Tyr Thr Trp Gln Gly Leu Ser Leu Asp Asp Gly Gln Asp Asn Ala Gly 805 810 815 Tyr Val Lys Phe Gly His Gly Ser Ala Gln His Val Arg Ala Gly Phe 820 825 830 Arg Leu Gly Ser His Asn Asp Met Thr Phe Gly Glu Gly Thr Ser Ser 835 840 845 Arg Asp Thr Leu Arg Asp Ser Ala Lys His Ser Val Ser Glu Leu Pro 850 855 860 Val Asn Trp Trp Val Gln Pro Ser Val Ile Arg Thr Phe Ser Ser Arg 865 870 875 880 Gly Asp Met Ser Met Gly Thr Ala Ala Ala Gly Ser Asn Met Thr Phe 885 890 895 Ser Pro Ser Arg Asn Gly Thr Ser Leu Asp Leu Gln Ala Gly Leu Glu 900 905 910 Ala Arg Ile Arg Glu Asn Ile Thr Leu Gly Val Gln Ala Gly Tyr Ala 915 920 925 His Ser Val Ser Gly Ser Ser Ala Glu Gly Tyr Asn Gly Gln Ala Thr 930 935 940 Leu Asn Met Thr Phe * 945 <210> 231 <211> 795 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(76654..79038) <400> 231 Met His Glu Lys Asn Ile Ala Leu Leu Cys Asp Glu Ala Asp Arg Leu 1 5 10 15 Leu Gln Leu Asn Ile Asn Leu Leu Arg Gln Met Val Asp Glu Pro Asp 20 25 30 Val Leu Ser Asp Ser Lys Asn Glu Asn Gly Leu Leu Phe Asp Lys Arg 35 40 45 Lys Ala Leu Lys Arg Ile Glu Glu Leu Glu Gly Glu Gln Ile Lys Thr 50 55 60 Ala Arg Arg Glu Met Val Leu Ala Val Val Gly Thr Met Lys Ala Gly 65 70 75 80 Lys Ser Thr Thr Ile Asn Ala Ile Val Gly Gln Glu Ile Leu Pro Asn 85 90 95 Arg Asn Arg Pro Met Thr Ser Val Pro Thr Leu Ile Arg His Val Pro 100 105 110 Gly Lys Thr Glu Pro Val Leu His Leu Glu His Ile Gln Pro Val Arg 115 120 125 Asn Leu Leu Ile Thr Leu Gln Glu Lys Leu Ala Thr Pro Ala Gly Gln 130 135 140 Gln Val Ala Gln Ser Leu Gln Gln Thr Gly Asp Thr Arg Glu Leu Leu 145 150 155 160 Asp Ile Leu Ala Asp Asp Val Trp Leu Lys Asn Glu Tyr His Gly Glu 165 170 175 Asp Glu Ile Phe Thr Gly Leu Ala Ser Leu Asn Asp Leu Val Arg Leu 180 185 190 Ala Ala Ala Met Gly Thr Glu Phe Pro Phe Asp Glu Tyr Ala Glu Val 195 200 205 Gln Lys Leu Pro Val Ile Asp Val Ala Phe Ser His Leu Val Gly Met 210 215 220 Asp Ala Cys Gln Gly Thr Leu Thr Leu Leu Asp Thr Pro Gly Pro Asn 225 230 235 240 Glu Ala Gly Gln Pro Gln Met Glu Met Met Met Arg Asp Gln Leu Gln 245 250 255 Lys Ala Ser Ala Val Leu Ala Val Met Asp Tyr Thr Gln Met Asn Ser 260 265 270 Lys Ala Asp Glu Glu Val Arg Lys Glu Leu Asn Ala Ile Ala Asp Val 275 280 285 Ser Ala Gly Arg Leu Phe Val Leu Val Asn Lys Phe Asp Glu Lys Asp 290 295 300 Arg Asn Gly Asp Gly Ala Asp Ala Val Arg Gln Lys Val Pro Ala Met 305 310 315 320 Leu Asn Ser Asp Val Leu Pro Ala Ser Arg Val Tyr Pro Gly Ser Ser 325 330 335 Arg Gln Ala Tyr Leu Ala Asn Arg Ala Leu His Glu Leu Arg Lys Asn 340 345 350 Gly Ala Leu Pro Val Asp Glu Ala Trp Val Asp Asp Phe Ile Arg Glu 355 360 365 Ala Phe Gly Pro Met Val Glu Glu Asp Asp Trp Lys Asp Ser Thr Lys 370 375 380 Val Asn Lys Lys Ala Glu Lys Leu Trp Asn Ile Ser Leu Ile Asp Gln 385 390 395 400 Leu Ile Thr Glu Val Ile Gln Ser Ser His Ser Arg Ala Ala Ala Leu 405 410 415 Ala Val Asp Ser Ala Ala Ala Lys Leu Met Gln Asn Ala Glu Asn Val 420 425 430 Ser Glu Tyr Leu Ser Leu Arg His Gln Gly Leu Gln Gln Ser Ile Gln 435 440 445 Ser Leu Gln Ala His Ile Thr Ser Leu Leu Ala Asp Ile Gln Glu Ile 450 455 460 Glu Glu Cys Gln Asn Gln Val Thr Gly Asp Val Arg Met Ala Met Glu 465 470 475 480 Asp Ile Asn Thr Lys Thr Gly Glu Leu Leu Thr Lys Val Cys Ala Ser 485 490 495 Leu Glu Glu Glu Leu Asn Asp Tyr Phe Arg Ser Gly Lys Arg Lys Glu 500 505 510 Gln Gln Met Leu Glu Glu Glu Asn Ser Ala Gln Pro Arg Glu Arg Asn 515 520 525 Ala Phe Ala Phe Phe His Asp Ile Phe Gly Thr Gly Asn Gln His Asp 530 535 540 Arg Met Arg Asp Phe Asp Pro Asp Ser Pro Glu Ile Lys Phe Ser Asp 545 550 555 560 Arg Arg Ala Ala Leu Glu Leu Met Thr Gln Ile Glu Ser Thr Val Thr 565 570 575 Ser Leu His Arg Glu Ala Glu Ala Gln Phe Arg Pro Glu Leu Glu Lys 580 585 590 Ile Val Ser Gly Ile Glu Thr Gly Phe Arg Gly Thr Ala Leu Tyr Ala 595 600 605 Thr Glu Asn Ile Ala Gly Arg Ile Asn Ala Arg Leu Glu Asp Glu Gly 610 615 620 Phe Thr Val Lys Ile Ser Phe Pro Ala Val Ser Gln Leu Gln Thr Arg 625 630 635 640 Leu Ala Val Lys Ile Asn Leu Ser Ala Leu Met Glu Glu Arg Thr Glu 645 650 655 Thr Val Thr Arg Arg Arg Arg Gln Ser Gly Val Trp Gly Thr Val Cys 660 665 670 Arg Trp Phe Gly Thr Ser Asp Leu Gly Trp Glu Asn Tyr Asp Glu Asp 675 680 685 Val Ser Arg Ser Val Ile Asn Ile Asn Lys Ala Arg Glu Glu Val Met 690 695 700 Ser Leu Thr Arg Ala Tyr Phe Gly Glu Leu Gln Ala Ser Ile Glu Gln 705 710 715 720 Asp Ile Asn Gln Pro Val Arg Gln Glu Ile Asp Ala Phe Phe Cys Ala 725 730 735 Phe Arg Glu Lys Val Glu Gln Leu Arg Asn Thr Leu Ile Gln Ser Ser 740 745 750 Glu Asp His Lys Arg Asp Gln Gln Ala Gln Glu Arg Leu Thr Gly Arg 755 760 765 Leu Gln Ala Leu Asn Glu Arg Val Pro Glu Leu Ile Thr Asp Ser Lys 770 775 780 Ala Leu Arg Glu Glu Leu Glu Thr Met Leu * 785 790 <210> 232 <211> 302 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(79035..79940) <400> 232 Val Thr Ser Pro Phe Ile Gln Gln Ile Ala Asp Asn Arg Val Cys Gln 1 5 10 15 Val Leu Thr Cys Leu Pro Glu Lys Phe Val Val Asp Phe Ala Asn Gly 20 25 30 Ile Asp Val Ala Gln Glu His Ile Arg Thr Ala Gly Glu Arg Thr Phe 35 40 45 Phe Arg Arg Leu Lys Glu Gly Leu Thr Gly Glu Gly Ala Ala Arg Gln 50 55 60 Asn Ala Ile Asn Ala Ser Leu Ala Gln Gly Val Glu Ala Ser Leu Arg 65 70 75 80 Trp Leu Thr Glu Met Thr Thr Ser Leu Ala Thr Thr Asn Tyr Ala Ile 85 90 95 Thr Arg Val Asn Asp Arg Val Ser Ser Leu Val Ser Asp Thr Ala Arg 100 105 110 Leu Ala His Tyr Ser Ala Asp Thr Arg Glu Gln Leu Leu Thr Leu Ala 115 120 125 Asp Gln Val His His Lys Leu Asn His Leu Glu Glu Lys Leu His Arg 130 135 140 Val Asp Gln Val Gln Arg Ala Gln Leu His Leu Glu Gln Ile Phe Ser 145 150 155 160 Trp Trp Ser Ala Gly Arg Tyr Ala Ser Phe Ser Pro Ala Gly Arg Cys 165 170 175 Tyr Val Ala Leu Glu Glu Leu Arg Trp Gly Ala Phe Gly Asp Val Ile 180 185 190 Arg Gln Gly Glu Thr Gly Gln Val Asn Gln Leu Leu Asp Ile Leu Arg 195 200 205 His Lys Ala Leu Thr Gln Met Ala Gln Glu Ser Gly Gly Ser Ala Thr 210 215 220 Val Arg Leu Asn Thr Leu Asp Trp Leu Gly Gly Gln Gly Arg Glu Gln 225 230 235 240 Ala Asp Asn Glu Trp His Asp Ala Ile Asn Trp Leu Gly Asp Trp Cys 245 250 255 Ser Glu Glu Gln His Pro Val Ile Trp Ser Thr Thr Gln Ala Ala Glu 260 265 270 His Leu Pro Val Arg Met Pro Arg Leu Cys Ser Ala Glu Arg Leu Ser 275 280 285 Glu Ser Met Val Asp Glu Ile Phe Gln Lys Gly Ala Ala * 290 295 300 <210> 233 <211> 357 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(79937..81007) <400> 233 Met Ser Thr Glu Met Lys Thr Gly Leu Val Leu Ser Gly Gly Gly Ala 1 5 10 15 Val Gly Ala Tyr Gln Ala Gly Val Val Lys Ala Leu Ala Glu Cys Gly 20 25 30 Thr Gln Ile Ser Met Val Ser Gly Thr Ser Ile Gly Ala Phe Asn Gly 35 40 45 Ala Ile Ile Ala Ala Ser Pro Asp Leu Ser Glu Ala Ala Val Arg Leu 50 55 60 Glu Ala Leu Trp Glu His Leu Gly Asn Asn Gln Val Leu Ser Val Asn 65 70 75 80 Arg Leu Val Tyr Phe Ser Leu Leu Lys Lys Leu Phe Gln Ala Met Asn 85 90 95 Leu Cys Gln Ile Pro Gly Arg Ala Gly Ala Leu Leu Thr Thr Leu Leu 100 105 110 Arg His Ile Ser Thr Ile Asn Gly Phe Asp Asn Leu Met Ala Gln Pro 115 120 125 Leu Leu Ser Asp Glu Pro Leu Thr Ala Leu Met Asp His Tyr Leu Asp 130 135 140 Thr Asp Ala Leu Ala Asp Gly Leu Pro Leu Tyr Val Ser Leu Tyr Pro 145 150 155 160 Thr Glu Gly Gly Met Gln Asp Ile Ile Asp Cys Ile Arg Ala Glu Leu 165 170 175 Gly Val Gly Thr Thr Lys Asn Ala Val Phe Gln His Ile Gln Ser Leu 180 185 190 Pro Arg Gly Gln Gln Lys Glu Ala Leu Leu Ala Ser Ala Ala Leu Pro 195 200 205 Leu Leu Phe Arg Pro Arg Glu Val Gln Gly Thr Met Phe Gly Asp Gly 210 215 220 Gly Met Gly Gly Trp Arg Asn Met Gln Gly Asn Thr Pro Val Thr Pro 225 230 235 240 Leu Val Asp Ala Gly Cys Asn Met Val Ile Val Thr His Leu Ser Asp 245 250 255 Gly Ser Leu Trp Asp Arg Gln Ala Phe Pro Asp Thr Thr Ile Leu Glu 260 265 270 Ile Arg Pro Arg Lys Arg Leu Lys Tyr Ala Gly Asp Gly Gly Asn Ser 275 280 285 Gly Gly Leu Leu Ser Phe Thr Ser Ala His Thr Asp Ala Trp Arg Gln 290 295 300 Gln Gly Tyr Glu Asp Thr Met Leu Ala Met Glu His Ile Arg Lys Pro 305 310 315 320 Leu Ala Ala Arg Gln Ala Leu Thr Arg Ser Glu Ala Val Leu Gln Lys 325 330 335 Ser Leu Asp Ile Thr Glu Glu Ala Asp Leu Ala Leu Arg Asn Ala Met 340 345 350 Ala Arg Ile Lys * 355 <210> 234 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(81112..81276) <400> 234 Met Gly Glu Met Asn Glu Val Tyr Cys Leu Arg Ser Pro Ser Leu Ala 1 5 10 15 Asn His Val Leu Ser Cys Ile Pro Ala Ser Pro Val Gln Leu Thr Phe 20 25 30 Ser Ile Ala Asp Asn Pro Pro Glu Ile Cys Ser Leu Val Val Phe Val 35 40 45 Ser Ser Pro Lys Ile Lys * 50 <210> 235 <211> 273 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(81347..82165) <400> 235 Met Arg Leu Ala Ser Arg Phe Gly Tyr Ala Asn Gln Ile Arg Arg Asp 1 5 10 15 Arg Pro Leu Thr His Glu Glu Leu Met Arg His Val Pro Ser Ile Phe 20 25 30 Gly Glu Asn Arg His Thr Ser Arg Ser Glu His Tyr Ala Tyr Ile Pro 35 40 45 Thr Ile Thr Val Leu Glu Asn Leu Gln Gln Glu Gly Phe Gln Pro Phe 50 55 60 Phe Ala Cys Gln Thr Arg Val Arg Asp Gln Ser Arg Arg Glu Tyr Thr 65 70 75 80 Lys His Met Leu Arg Leu Arg Arg Ala Gly Gln Ile Thr Gly Gln His 85 90 95 Val Pro Glu Ile Ile Leu Leu Asn Ser His Asp Gly Ser Ser Ser Tyr 100 105 110 Gln Met Leu Pro Gly Tyr Phe Arg Ala Ile Cys Thr Asn Gly Leu Val 115 120 125 Cys Gly Gln Ser Leu Gly Glu Leu Arg Val Pro His Arg Gly Asn Val 130 135 140 Val Asp Arg Val Ile Glu Gly Ala Tyr Glu Val Val Gly Val Phe Asp 145 150 155 160 Arg Ile Glu Glu Lys Arg Asp Ala Met Gln Ser Leu Val Leu Pro Pro 165 170 175 Pro Ala Arg Gln Ala Leu Ala Gln Ala Ala Leu Thr Tyr Arg Tyr Gly 180 185 190 Asp Glu His Gln Pro Val Thr Thr Ala Asp Ile Leu Thr Pro Arg Arg 195 200 205 Arg Glu Asp Tyr Gly Lys Asp Leu Trp Ser Ala Tyr Gln Thr Ile Gln 210 215 220 Glu Asn Met Leu Lys Gly Gly Ile Ser Gly Arg Ser Ala Lys Gly Lys 225 230 235 240 Arg Ile His Thr Arg Ala Ile His Ser Ile Asp Thr Asp Ile Lys Leu 245 250 255 Asn Arg Ala Leu Trp Val Met Ala Glu Thr Leu Leu Glu Ser Met Arg 260 265 270 * <210> 236 <211> 162 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(82256..82741) <400> 236 Met Thr Thr Val Ser His Asn Ser Thr Thr Pro Ser Val Ser Val Thr 1 5 10 15 Thr Ala Ser Gly Asn Asn Pro Pro Gln Leu Val Ala Thr Pro Val Pro 20 25 30 Asp Glu Gln Arg Ile Ser Phe Trp Pro Gln His Phe Gly Leu Ile Pro 35 40 45 Gln Trp Val Thr Leu Glu Pro Arg Val Phe Gly Trp Met Asp Arg Leu 50 55 60 Cys Glu Asp Tyr Cys Gly Gly Ile Trp Asn Leu Tyr Thr Leu Asn Asn 65 70 75 80 Gly Gly Ala Phe Met Ala Pro Glu Pro Asp Asp Asp Asp Asp Glu Thr 85 90 95 Trp Val Leu Phe Asn Ala Met Asn Gly Asn Arg Ala Glu Met Ser Pro 100 105 110 Glu Ala Ala Gly Ile Ala Ala Cys Leu Met Thr Tyr Ser His His Ala 115 120 125 Cys Arg Thr Glu Cys Tyr Ala Met Thr Val His Tyr Tyr Arg Leu Arg 130 135 140 Asp Tyr Ala Leu Gln His Pro Glu Cys Ser Ala Ile Met Arg Ile Ile 145 150 155 160 Asp * <210> 237 <211> 159 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(82757..83233) <400> 237 Met Gln Gln Leu Ser Phe Leu Pro Gly Glu Met Thr Pro Gly Glu Arg 1 5 10 15 Ser Leu Ile Leu Arg Ala Leu Gln Thr Leu Asp Arg His Leu His Glu 20 25 30 Pro Gly Val Ala Phe Thr Ser Thr Arg Ala Ala Arg Glu Trp Leu Ile 35 40 45 Leu Asn Met Ala Gly Leu Glu Arg Glu Glu Phe Arg Val Leu Tyr Leu 50 55 60 Asn Asn Gln Asn Gln Leu Ile Ala Gly Glu Thr Leu Phe Thr Gly Thr 65 70 75 80 Ile Asn Arg Thr Glu Val His Pro Arg Glu Val Ile Lys Arg Ala Leu 85 90 95 Tyr His Asn Ala Ala Ala Val Val Leu Ala His Asn His Pro Ser Gly 100 105 110 Glu Val Thr Pro Ser Lys Ala Asp Arg Leu Ile Thr Glu Arg Leu Val 115 120 125 Gln Ala Leu Gly Leu Val Asp Ile Arg Val Pro Asp His Leu Ile Val 130 135 140 Gly Gly Asn Gln Val Phe Ser Phe Ala Glu His Gly Leu Leu * 145 150 155 <210> 238 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(83296..83517) <400> 238 Met Arg Ile Ile Thr Arg Gly Glu Ala Met Arg Ile His Gln Gln His 1 5 10 15 Pro Ala Ser Arg Leu Phe Pro Phe Cys Thr Gly Lys Tyr Arg Trp His 20 25 30 Gly Ser Ala Glu Ala Tyr Thr Gly Arg Glu Val Gln Asp Ile Pro Gly 35 40 45 Val Leu Ala Val Phe Ala Glu Arg Arg Lys Asp Ser Phe Gly Pro Tyr 50 55 60 Val Arg Leu Met Ser Val Thr Leu Asn * 65 70 <210> 239 <211> 125 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(83680..84054) <400> 239 Val Ser Asp Lys Leu Ser Gly Ile Thr His Pro Asp Asp Asn His Asp 1 5 10 15 Arg Pro Trp Trp Gly Leu Pro Cys Thr Val Arg Pro Cys Phe Gly Ala 20 25 30 Arg Leu Val Gln Glu Gly Asn Arg Leu His Tyr Leu Ala Asp Arg Ala 35 40 45 Gly Ile Arg Gly Arg Phe Ser Asp Ala Asp Ala Tyr His Leu Asp Gln 50 55 60 Ala Phe Pro Leu Leu Met Lys Gln Leu Glu Leu Met Leu Thr Ser Gly 65 70 75 80 Glu Leu Asn Pro Arg Tyr Gln His Thr Val Thr Leu Asn Ala Lys Gly 85 90 95 Leu Thr Cys Glu Ala Asp Thr Leu Gly Ser Cys Gly Tyr Val Tyr Leu 100 105 110 Ala Val Tyr Pro Thr Pro Ala Pro Ala Thr Thr Ser * 115 120 <210> 240 <211> 125 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(84101..84475) <400> 240 Met Lys Thr Leu Ser Asp Thr His Val Arg Glu Val Ser Arg Cys Pro 1 5 10 15 Ser Pro Val Thr Ile Trp Gln Thr Leu Leu Ile Arg Leu Leu Asp Gln 20 25 30 His Tyr Gly Leu Thr Leu Asn Asp Thr Pro Phe Ala Asp Glu Arg Val 35 40 45 Ile Glu Gln His Ile Glu Ala Gly Ile Ser Leu Cys Asp Ala Val Asn 50 55 60 Phe Leu Val Glu Lys Tyr Ala Leu Val Arg Thr Asp Gln Pro Gly Phe 65 70 75 80 Ser Thr Cys Pro Arg Ser Gln Leu Ile Asn Ser Ile Asp Ile Leu Arg 85 90 95 Ala Arg Arg Ala Thr Gly Leu Met Thr Arg Asp Asn Tyr Arg Thr Val 100 105 110 Asn Asn Ile Thr Leu Gly Lys Tyr Pro Glu Ala Lys * 115 120 <210> 241 <211> 164 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(84472..84963) <400> 241 Met Met Lys Leu Ala Leu Thr Leu Glu Ala Asp Ser Val Asn Val Gln 1 5 10 15 Ala Leu Asn Met Gly Arg Ile Val Val Asp Val Asp Gly Ile Glu Leu 20 25 30 Ala Glu Leu Ile Asn Met Val Cys Asp Asn Gly Tyr Ser Leu Arg Val 35 40 45 Val Asp Glu Ser Asp Gln Thr Ser Ala Glu Cys Thr Pro Pro Phe Ala 50 55 60 Thr Leu Thr Gly Ile Arg Cys Ser Thr Ala His Ile Thr Glu Thr Asp 65 70 75 80 Asn Ala Trp Leu Tyr Ser Leu Ser His Gln Thr Ser Asp Phe Gly Glu 85 90 95 Ser Glu Trp Ile His Phe Thr Gly Asn Gly Tyr Leu Leu Arg Thr Asp 100 105 110 Ala Trp Ser Tyr Pro Val Leu Arg Leu Lys Arg Leu Gly Leu Ser Lys 115 120 125 Thr Phe Arg Arg Leu Val Val Thr Leu Ile Arg Arg Tyr Gly Val Ser 130 135 140 Leu Ile His Leu Asp Ala Ser Ala Glu Cys Leu Pro Gly Leu Pro Thr 145 150 155 160 Phe Asp Trp * <210> 242 <211> 66 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(84975..85172) <400> 242 Met Lys Ser Leu Thr Thr Glu Thr Ala Leu Asp Ile Leu Ile Ala Trp 1 5 10 15 Leu Gln Asp Asn Ile Asp Cys Gly Ser Gly Ile Ile Phe Asp Asn Asp 20 25 30 Glu Asp Lys Thr Asp Ser Ala Ala Leu Leu Pro Cys Ile Glu Gln Ala 35 40 45 Arg Glu Asp Val Arg Thr Leu Arg His Leu Gln Leu Leu His Gln Asn 50 55 60 Arg * 65 <210> 243 <211> 281 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(85257..86099) <400> 243 Met Ser Asp Ile Thr Ile Ser Arg Pro Glu Val Val Asn Gly His Thr 1 5 10 15 Asp Val Ile Cys Ser Thr Ser Ile Arg His Ile Leu Ala Val Arg Lys 20 25 30 Ser Thr Leu Leu Gln Ile Asp Thr Leu Ile Arg Gln Leu Ala Glu Ile 35 40 45 Ser Val Leu Thr Glu Ser Ile Gly Gly Lys Thr Ala Pro Asp Trp Ala 50 55 60 Met Lys Gln Asp Phe Arg Cys Gly Cys Trp Leu Met Glu Lys Pro Glu 65 70 75 80 Thr Ala Met Lys Ala Ile Thr Arg Asn Leu Asp Arg Glu Ile Trp Arg 85 90 95 Asp Leu Met Gln Arg Ser Gly Met Leu Ser Leu Met Asp Thr Gln Ala 100 105 110 Arg Asp Thr Trp Tyr Arg Ser Leu Glu Tyr Asp Asn Phe Pro Glu Ile 115 120 125 Ser Glu Ala Asn Ile Leu Ser Thr Phe Glu Gln Leu His Gln Asn Lys 130 135 140 Asp Glu Val Phe Glu Arg Gly Val Ile Asn Val Phe Arg Gly Leu Asn 145 150 155 160 Trp Asn Tyr Lys Thr Asn Cys Pro Cys Lys Phe Gly Ser Lys Ile Ile 165 170 175 Val Asn Asn Leu Val Arg Trp Asp Arg Trp Gly Phe His Leu Ile Thr 180 185 190 Gly Gln Gln Ala Asp Arg Leu Ala Asp Leu Glu Arg Met Leu His Leu 195 200 205 Phe Ser Gly Lys Pro Ile Pro Asp Asn Arg Gly Asn Ile Thr Leu Arg 210 215 220 Leu Asp Asp His Ile Gln Ser Val Gln Gly Lys Glu Ser Tyr Glu Asp 225 230 235 240 Glu Met Phe Ser Ile Arg Tyr Phe Lys Lys Gly Ser Ala His Ile Thr 245 250 255 Phe Arg Lys Pro Glu Leu Val Asp Arg Leu Asn Asp Ile Ile Ala Lys 260 265 270 His Tyr Pro Asp Met Leu Ala Val * 275 280 <210> 244 <211> 62708 <212> DNA <213> Escherichia coli O157:H7 <400> 244 gtttcaacat gtctaaggat atggtttatc attttgaaaa atataatttt atttcatcct 60 cctggtcact ttggggcacg tctggggcac gggcattaag gacattattc aacatggcaa 120 cttgagtcac gctgcactca ggcatccatg caccataaac attgtagacc atgctggcgc 180 tggagtgccc catctgtgat gcaataaatg tcgggtttgc tccggaagat aaagcccagc 240 acgcataggt atggcgtgac tgatacgctt tacgggatcg gatacccgct ctttttattg 300 ctgaatccca tgtcgctccg atggagctta ccgcgtagtt aatacccgcc ttgtgattct 360 tgcgaacgat ttgcggacag aaaacaaaag tgcactcgtg caaaattgtt cttccgtact 420 cgcgtaattg aacagtgatc tgatgctgcc tgctaagacg agtaagcatc gcctggtttt 480 taagtgcttc aattgctggt gccagaagat gtataacccg gttagtgcct gcgtcggtct 540 ttggtagcgt aaaatcacct atttttgtaa aatttcgtcg cactgttatc gtgccagctt 600 tcaggtcgat atcctcccat gcaagtgcgg caatttcacc gtgtcgcatc cctgtaaaaa 660 cagccactgt ccagaggttt ttggtctgtt gatgatggca ggcatcaatg agacggctaa 720 actcatctct ggtcagtgga tccggcactg gttttgattt cctcagcggt gttattgaat 780 taaacgggtt tttctccaga tacccgtttt cggcggcaaa gctgaacatt ccggctgttg 840 ttgtcatgta atagttcact gtgggtacgg ttcttccttt tcgggacgtg ctggttttcc 900 tgcttccctt ttccccggtc agtaaatctt tcctgataaa cagcagatct tcttttgtaa 960 tcgatgacgc cagcctgcca ggaccaagcc tcggtagcat atttttcatc actgattgat 1020 aacgatttaa ggcgttacta ccgatttcca ttgctttcag agtaagccat ttctgtgcca 1080 gttcaccgac ggtgatatct ttttttacca ggccaaatag cttcaggtta ggtgagtcag 1140 ggaatcgatc ggcataatca aacgttcctg ttctgattgc aaagcagacc gaagccctta 1200 actcaccagc gatctttctg tttttcggtg tatcgggcac gcgaagattt tcgcgcactc 1260 gtttacccct gtacttaaac gttattcgga gttttcctcc gtgattttca acgccggctg 1320 gataggctga attcgccatt gttcctcctg cgtccaagag cacgctcagg ttatactctt 1380 atggacaaga attaaacatc ctgagatggt aagggttggt ttttgatcca agtgttgatg 1440 gtaggaagat gatagagaca ttcgctgttt ttctttggcg ttccgtcggg ggcgatttgt 1500 ttatattctc tgccgttcat ccacgcactg tccctggcgc gtaatattgt tccttttctc 1560 aggcctgtta cagccattaa aagctccagt gttacccatt cattcgcatt tatctgtaca 1620 acaggtgtga tgactggctg aatgccatgg ttatgttggt ttactaactc gcgcataagt 1680 tgcctctgca tgtgtaagaa aaaaccgcca tcaggcggct tggtgttctt tcagttcttc 1740 aattcgaata ttggttacgt cttattcgat gcgcactcct ggtatttcgc cttttgatat 1800 tgctaagtca taaatttgcg cggcactata cccatctcgc atccatgaat ctaaggcgcg 1860 aacagcctcg ctacgctttt tatcttctct ctcatttttg atatcaacga ggacatcaac 1920 gcaattaagg caaatgtgga ttttgtcttt acattcgatc atggcggctt tgccatgatt 1980 tccgccacac agtgagcata aatcttcagg gtctggctgg tatttctgta acgttagagg 2040 gttgaatgtt gaacaggcca taatcatctc cataaaacaa aactcgccgt agcgagttca 2100 gataaaagaa atccccgcga gtgcgaggat tgttattcat tgccgatatt cacctttatc 2160 gcgaacacct ttaccggttt atcaccgaag tgcggatgtg tgattgtctt gatttcatat 2220 ccgtcatacg gaacatcaat tcttcggctg gaatcgtcgc gcttcggata tccctttgtg 2280 ataatcaggc ggtcatactc gcggaacata attcgcttat tccagtagtc attaaacagg 2340 cgatactctt ccgttttctc tccgcgaatc atggcatcga agtattcacc tttaacggca 2400 agttgcaggt tagccacggt taacctcctg cggcggttct ggtagcggca tccagtgagt 2460 tgcttgctca ataccattac ccggcttaat cgttgcatct ccgcgccgaa aggtgcttcc 2520 ggtatagcgt gcggagcata ttagcggttc aaccagagag ctatcgaaat tcaccgaaat 2580 aagcacgttc tggccctttt caggcattcg atcactacag cttatccaac tatccggagt 2640 taccggagag ttaccagcct cataagcgga tttcatccag tgcgtaagcg tttcgatgct 2700 tacacatccg caatcaacgt ctattttttc tttttgttct gacaaccatt cctggaatga 2760 cagcttggca gtctggcttg ctggatcaat tcgtggcagg ccgatatata gtggtacatt 2820 tcccggctcc atcgaattgt cgggacaaat aaacgtgtta caaccatatt taacgagctc 2880 aattcccact gtgtcgatag tggcgaatgg ttcagtggtc aatgcagtca acgcaatttc 2940 ataagcacgg cgctcaatat tatctcgcac gtccaggctg ccgattcgct ctttgatttc 3000 tttaatcatt tctttgtcgg tgaacgttgt catgtgttag tccttatcca cttcaacgcc 3060 atctttcagc gtgatgccgt gccaatcatc agcccaactg gttaacccag gcgcatcaat 3120 gctaggcata tagacgcttg cagtgtggta gcccttatcg ttatcaatgc tggcaacgtg 3180 ctcgccgttg tatgcgctca gcgtgtctag gacactataa aactttcctc cggctgccct 3240 gaaatccttt acagccttca caagacgatt ccacgctttt tcctgttctg gcgtcaggtc 3300 gattaattcc tgcaaagttg ccatttcagt tttccttata tgggttaatt ttattgtgca 3360 gtgtgttgaa cgacgcccat accacgtcgt tatacaactc aataactagc tcaattattt 3420 tcccgattgc ccagacaaaa attagcgggg atatcggtgt catcaacacg ataaacagaa 3480 tgagaaacaa aaattctgtc gctctacttt ttcgcggata ttcttttctg aataatgtag 3540 gcacatcact ctcctttgtt gctcctcaaa attttatgcc ctggcgcaaa agcacgcgtt 3600 ttgtctttgc ttattcgcca gccatccttg cgcgcctctt ttgcacagcc agcccatgac 3660 gtaccgatat actcaccgaa gtctggcgac ttatatttgc catctgtaca ctggaggcaa 3720 tcacaataga gatgcatggt gtaacttgca gcaatagcca tatcactctc ctttagtgcg 3780 caagtggttt ttccagcggt tttgctccgc gctgggcttt ttgcaaaaac cacaatccat 3840 catcccgtaa tatttcatca accccatccg tcggttgctg agtctcaccc actgccagac 3900 gccaggagcg tttctacgaa ctaacagaat ctttgcttta cggtttttca tcgttttgct 3960 ctcctgcatc tctttgctgc tcgtcgtgcc gctgcaatac cggtatggcg gcgctttggt 4020 gtcgggatga tgttctttgc aattagcgca gaagcccaaa aacgagtcgg atacggtaac 4080 aagccgatac atgccacacg cattactcac ctcttttgat gcgaatgcca gcggcgcgct 4140 cggcttcact ttgttcccaa aaccacttgt gaagcgccat aagcttttcg tcaatcggtg 4200 catatttgcg attaaagtag gcctgagcat ctttctcaga ttcgtccggt aattcgccag 4260 ggccaaacag tgtgttataa atccatgcta gtccgctctt agcgtcgcca gttgcctgcc 4320 attcgataat ggcagcctgc atgaccagaa tgtttttccc gattaatagg tccagttctt 4380 tgtaccggtt gcggatgtat gcattctcgc tttgtaattt tgcgttgcgc ttttctgagg 4440 cttcaagtaa cgcctgctta tcgcgtagag cttcttccag ttcagcaaca tggcattcac 4500 tatcaataag gttgttctct gctgcttcaa gctcaacacg cagcttccca accgtaagcg 4560 caatctcctc gttctcctgg tcgcggcgtt tgatgtattg ctggtttctt tcctgttcat 4620 ccagcagtgc cagcacggta gccgggttag cctctgctat gaattcagcg tttgcataag 4680 cctgatcatc tgattcaatc aggcagttaa catgacattc cgcaatcacg ccaccgggtt 4740 ctcctttcca tttttggcaa acaaaaactc ctgttaaatt gccgtgctgg ttaacagatg 4800 tatgccctac gatgtagctt cctttagttg ctttctctgc cttttcacgc agtgcctgat 4860 aattaatttc gctcacttcg aacctctctg tttactgata agctccagat cctcctggca 4920 acttgcacaa gtccgacaac cctgaacggc caggcgtctt cgctcatcta tgggatcgcc 4980 acactcacaa caatgagtgg cagatatagc ctggtggttc aggcggcgca tttttattgc 5040 tgtgttgcgc tgtaattctt caatttctga tgctgaatca atgaggtctg ccatctttca 5100 ttaatccctg aattgttggt taatacgctt gagggtgaat gcgaataata aaaaaggagc 5160 ctgtagctcc ctgatgattt tgcttttcat gttcaccgtt ccttaaagac gccgtttaac 5220 atgccgatcg ccagacttaa atgagtcggt gtgaatccca ttagcgttac cgtttcgcgg 5280 tgcttcttca gtacgctacg gcaaatgtca tcgacgtttt tatccggaaa ctgctgtctg 5340 gcttttttga tttcagaatt agcctgacgg gcaatgctgc gaagggcgtt ttcctgctga 5400 ggtgtcattg aacaagtccc atgtcggcaa gcataagcac acagaatatg aagcctgctg 5460 ccagaaaaat gcattctgtt gttgtcatgc cgggtctctc tcgtttgctt ctgctttcgc 5520 cgccatcatt tccagctttt gtgaaaggga tgtggctaac gtatgaaatt cttcgtctgt 5580 ttctactggt attggcacaa acctgactcc aatttgagcg aggctatgtg ccatctcgat 5640 actcgttctt aactcaacgg gagatgcttt gtgcatacag ctccccgttt attatttatc 5700 tcctcagcca gccgctgtgc tttcagggga tttctgataa cagaaaggcc gggaaatacc 5760 cagcctcgct ttgtaacgga gtagacgaaa gtgatcgcac ctacccggat attatcgtga 5820 ggatgcttca tcgccattgc tccccaaata caaaaccaat ttcagccagt gcctcgtcca 5880 ttttttcgat gaactccggc accatctcgt caaaactcgc catgtacttt tcatcccgct 5940 caaccacgac ataatgcagg ccttcacgct tcatacgtgg gtcatagttg gcaaagtacc 6000 aggcatcttt tcgtgtcacc cacatgctgt actgcacctg ggccatgtaa gccgacttta 6060 tggcctcgaa accaccgagc cggaacttca tgaaatcccg ggaggtaaac gggcatttca 6120 gctcaaggcc attgccgtca ctgcataaac catcgggaga gcaggcggta cgcatacttt 6180 cgtcgcgata gatgatcggg gattcaataa cattcacgcc ggaagtgaac tcaaacaggg 6240 ttctggcgtc gttctcgtac tgttttcccc aggccagtgc tttagcgtta acttccggag 6300 ccacaccggt gcaaacctcg gcaagcaggg tgtggaagta ggacattttc atgtcaggcc 6360 acttctttcc tgagcggggc tttgctatca cgttgtgaac ttctgaagcg gtgatgacgc 6420 cgagccgtaa tttgtgccat gcatcatccc cctgttcgac agctctcacg tcgattccgg 6480 tacgctgcag gataatgtcc ggtgtcatgc agccaccttc tgctcagagg ctttctgttt 6540 caggaatcca agaactttca ctgcttcggc ctgtgtcagt tctgacgatg cgcgaatgtc 6600 gcggcgaaat atctgggaac agagcggcaa taagtcgtca tcccatgttt tatccagggc 6660 gatcagcaga gtgttaatct cctgcatggt ttcatcgtta accggagtga tgtcgcgttc 6720 cggctggcgt tctgcagtgt atgcagtatt ttcgacaatg cgctcggctt catccttgtc 6780 atagatacca gcaaatccga aggccagacg ggcacactga atcatggctt tatgccgtaa 6840 catccgtttg ggatgcgact gccacgggcc ggtgatttct ctgccttcgc gggttttgaa 6900 tggttcgcgg cggcattcat ccatccactc ggtaacgcag atcggatgat tacggtcttt 6960 gcggtaaatc cggcatgtac aggattcatt gtcctgctca aagtccatgc catcaaactg 7020 ctggttttca ttgatgatgc gggaccagcc atcaacgccc accaccggaa cgatgccgtt 7080 ctgcttatca gggaaggcgt aaatttcttt cgtccacgga ttaaggccgt actggttggc 7140 gacgatcaac aatgcgatga actgcgcatc gctggcatca cctttaaatg ccgtctggcg 7200 aagagtggtg atcagttcct gtgggtcgac agaatccatg ccgacacgtt cagccagctt 7260 ccctgccagc gttgcgagtg ctgtactcat ccgctttata cctctgaatc aatatcaacc 7320 tggtggtgag caatggtttc aaccatgtac cggatgtgtt ctgccatgcg ctcctgaaac 7380 tcaacatcgt catcaaacgc acgggtaatg gcttttttgc tggccccgtg gcgttgcaaa 7440 tgatcgatgc agagtgattc aaacaggtgc tggggcagac cttttcccat gtcgtctgcc 7500 agttctgcct ctttctcttc acgggcgatc tgctggtagt gacgcgtcca gctctgagcc 7560 tcaagacgat cctgaatgta ataagcgttc atggctgaac tcctgaaata gctgtgaaaa 7620 tatcgcccgc gaaatgccgg gctgattagg aaaacaggaa agggggttag tgaatgcttt 7680 tgcttgatct cagtttcagt attaatatcc attttttata agcgtcgacg gcctcacgaa 7740 acatcttttc atcgccaata aaagtggcga tagtgaattt agtctggata gccataagtg 7800 tttgatccat tttttgggac tcctggctga ttaagtatgt cgataaggcg tttccatccg 7860 tcacgtaatt tacgggtgat tcgttcaagt aaagattcgg aagggcagcc agcaacaggc 7920 caccctgcaa tggcatattg catggtgtgc tccttattta tacataacga aaaacgcctc 7980 gagtgaagcg ttattggtat gcggtaacgc cgcgctcagg cggctttgat agtcatatca 8040 tctgaatcaa atattcctga tgtatcgata tcggtaattc ttattccttc gctaccatcc 8100 attggaggcc atccttcctg accatttcca tcattccagt cgaactcaca cacaacacca 8160 tatgcattta agtcgcttga aattgctata agcagagcat gttgcgccag catgattaat 8220 acagcattta ataaagagcc gtgtttattg agtcggtatt cagagtctga ccagaaatta 8280 ttaatctggt gaagtttttc ctctgtcatt acgtcatggt cgatttcaat ttctattgat 8340 gctttccagt cgtaatcaat gatgtatttt ttgatgtttg acatctgttc atatcctcac 8400 agataaaaaa tcgccctcac attggagggc aaagaagatt tccaataatc agaacaagtc 8460 ggctcctgtt tagttacgag cgacattgct ccgtgtattc actcgttgga atgaatacac 8520 agtgctgtgt ttattctgtt gtttatgcca aaaataaagg ccaccatcag gcagccttgt 8580 tgtaaatgtt gcaggtatca agtaagtaat tagatggagc gccataaatt atgaattcat 8640 cgtttgtcgg gtccatctcc atctcttgtc ctattgccat tcttgcgtca gtgtcgtcag 8700 cggcgaagca taaaacagcc cacgcaccca ttgttttaaa aagaactgca attggctgtg 8760 gttttactga atttgcgtta gcgcgaaaat cacaaatcgc actttcatga aattccatat 8820 atcacctcaa ataagtggtt tgctgcctaa tttcattttc tggcgaccaa cacaagtcat 8880 cttgctgtca gttgtttgga tttacggtag cctgccgcgt aaagagctac atttggaaga 8940 caagttgagc cttcatattt tctggtcaac gttgtcagtg ttattacttc tgctctcatt 9000 gctggtttgc gtttgcattg taagaccact cgtgatgggg ttggcctgtg tagtttgtcg 9060 gagctaatcg cctcctgact ttgcaggttt gcgcgacgag ctctacggcg agaagctgcg 9120 gtgcctttaa attctgtttt tctggacata gattcctccc gaataaactt tggcgatgca 9180 atctcgaagc tcctcctgag acggttgctt cggcattgca tcccacagct tatgtggttg 9240 ggtgatctgg cttttcagcc acgtagtcga gagtcgacgt tgtttaaaga gcctgccagt 9300 ctgttccatt tggcttccag cgtcctgctg atggttaaat agtacgatat gtacttcact 9360 tggtcaatac aatttgttct aaaacggggc gtttttttac aacgctttgt atttaatagt 9420 attgtttttt agcgtgggtg tattgcctcg gcgatgtaag gagagatcag aattgcgttg 9480 tttagtgagt tgtatctatt tattttccaa taaatacaat tggttatgtg tttttttggg 9540 cgagaggaaa agaaaacccg gcatggaggc cgggttgatg attagcggtg tggccttgag 9600 cgataatgct cacacacatg ttcaagattt ccatgcctta tccgttcata ggcattcaca 9660 tgaacttctc gatcgaattg gtcattcaaa ttgtatgtag acatctgtgt tttctcatat 9720 tggcggcagc cctacaaccg cttgaaaaaa tgtaccagac gcgctaaggt tacatcgcaa 9780 atattgtgta ccttaacaag ggctcctttt ggaggctctg gttaaacagc atcaatgtcg 9840 gactggggag ttggacattg tgctgaatgc ttttgcatta ttgaggccga acgtaaacct 9900 tcagaattga agagatgcgt tcggcttctt cgtttgtgat atcgttagga atgcctttaa 9960 tcgttactgt aacccctgat tcaggtcgaa gaactactgg aagatcatag gtatgaagtg 1002 0 cattagcctt gccttcgact tttgttggtt cgccagtcaa atctttttcc tcactggatt 1008 0 ctttgtcaat cggagtgtat gggatttctt caccagactg gaaagctaca aactttttga 1014 0 ttgcactttc catgcggctt ttatatgcag taatgctgct gtcgctaggc ttcggctcag 1020 0 ttgcgttgat gtatcgctcg gcaagctcat tcacatcaag ctgagtaaca tcacccattt 1026 0 cctcttcttg gactaccgtt aagaggcgag cggatgagtt ttttaaattt cgagcggtgg 1032 0 cctccttcat tatgttcagc gacataagct cttcaaggaa gtccttgaat gcctgcacgc 1038 0 taacgtttga ctttgccatt tgctctctct ctaagttatt gactcagatc gagtttatcc 1044 0 aggaattgat ttgcatgcaa gactcaagtc ttgagaattt ccgttcaaga tccactctca 1050 0 ataaaaaagg ccgcacctct gcgacctttc atctcctaaa tctcttttct cttacctaaa 1056 0 gaaacagcag gctgggtcag ccctaacaac ttcaagtgca tcggtcagag aaagctccgt 1062 0 gctatacagg tgttatttca tatctttttg catccaataa attttccatc tgtccagaga 1068 0 gcggatgcac ttgattcttg ttgatggcag gacgtttttt cacctgcctc accctgccat 1074 0 acaggacgct gctcaccgat atctatcgtc cggtcattga tgttatagac aatatccaga 1080 0 tcattacgga tatactcaga tggccttatg ctttcaatga atagatgaac ttctttttga 1086 0 ccgcttgata ctcatggcca ttaaactcca tctatcctct ttacccaaac gtctcttcag 1092 0 gccattggcc ggcgataact ttccccacaa cggaacaact ctcattgcat gggatcattg 1098 0 gatattgcgg gtttagtggt tgtagaaaca cctgaccgct atccctgatc agtttcttga 1104 0 aggtaaattc atcaccacca agtctggcta tgcagaaatc gccgggctca acagcttgct 1110 0 cagggtcaac cagaattaac atcccgtcag gaaaactagg tttggaacct gttggtgcgg 1116 0 tcattgagtt accttcaacc tcaagccaga atgcagagtc actggctttt ttggttgtgc 1122 0 ttaccaatct ctccgcatca cctttggtaa aggttctgag ttctggagag aacatcccag 1128 0 cctgaacatg agaaaaaaca gggtactcat attgtttttt aactggggcc gatgagtatt 1134 0 cgccaacagg tgaaaatgtc ccgtcgtggt tgaatgatat gttatcaata ccaaggtatt 1140 0 taaacaccac accaatatca ctaagagatg gatgacgaga tccgcgcaac cagtgtccaa 1146 0 ttccaccctg cgtcatacct agctcttcgg ctaacttctc ttgagttatg ccgagctctt 1152 0 tcattctgga tctagccagt tcataccatt tcattttcat gtccttatta ttacgctctg 1158 0 tactggaacc atccatgcac aatgtgtatt tttacttgta tttgagaagt acatattgta 1164 0 tttttttatt cgtggttact atggagggca tatgagcaac ctacgaaaat atcgagagtc 1170 0 actgaatatc tctcaaacaa cacttgctaa ggcagttgga tgcacacagg gagctatcgg 1176 0 acattgggaa tctggtcgtc gcttcccaga ccttaaaaca tgccgtgctc ttgttgcgtg 1182 0 tctaaacaag ttaggcgcaa aagtaagtct tgatgacgtg ttcccgccgg agcacaaagc 1188 0 cgcttaataa gcggagccgc tctttgtaac aacggacatt cgtcctacgt cgctgaaaag 1194 0 cgagtcccaa gatatctgac caactaaggc catatgcgtt tccacgcata cctttcaact 1200 0 agctattcac tattggaaat cttaagaaat ggaacaaaca agttacagca aactatcaca 1206 0 gcgagaaatt gatcgcgctg aaactgattt actcatcaac ctgtcaacgc ttacccagcg 1212 0 cggtctggca aagatgattg gctgtcatga atcgaagata agcagaacgg actggagatt 1218 0 tattgcttcg gtcttgtgtg ctttcggaat ggcatcagac atcagtccga ttagcagggc 1224 0 ttttaagtat gcgcttgatg aaatcacaaa gaaaaaatcc ccggccgcca ccgaggattt 1230 0 taagcaaatt gatatgcaat tctgagggaa ttactggatc aatccacagg agtaattatg 1236 0 acaaaacaac tcagtcctta ccaggacaaa attcacaaac acatactacg tgatcgcttc 1242 0 ctgtccagct tcaagcagcc tggtcgattc cgggctgagt tggaaaaagt gaagctgatg 1248 0 cagaaggaga aaggtcatga gtaacatatc taatctagcc gaagccagag aggcaagaag 1254 0 gctacaacaa ccgcatcaaa gcagcggtaa ggggtatgcc ttgctgcacc gtaaaattat 1260 0 ggatgtgccg ttttacaagg acgcagaagc tgcgcatctg tgggttcact taatcctcaa 1266 0 agcaaagcat acgcctgagt atgtaatgac tgacgcagga gaaattctgg taggcagagg 1272 0 gaagctactt ggcggtagaa actctctggc gtttgaaaca ggactcaaac cagatcgcgt 1278 0 tcagtacctg cttagaaagt tcaaaaaact cggcatgatt gactgggttt cacacggtaa 1284 0 attctcagtt ttctcggtag agaaatatga cgattatcag tcaaattttg taccagcaga 1290 0 ttaccagcaa attaccacct caaagccagc aataccaatg cctgcaagca atactgtacc 1296 0 agcagattac cagcaaatta ccacagataa agaatataat aatattatct ctaatactga 1302 0 cgtattagag agtgccacag cagacaaaaa gtctgacaag aaaaaacctt ccgttagctg 1308 0 tcaggatgtt gtcgatgctt accacgaaat ccttcctgaa gcgccaaaaa tccgcgcact 1314 0 gaatgacaag cgtaaaaacc agatccgaac gttctggcgc aaagccggag tgataacccg 1320 0 ccagcttgac gggcatgggt tcacgatgca ggactggaga aattatttga gctacgtagg 1326 0 cgaaaattgc cgatggatgt tcgaagagcg cccaaaccat cagcgcggaa ccgtctggca 1332 0 caaaaaggga tttgatttcc tgcttaacga taatacctac ctgaaagttc gtgagggtga 1338 0 acacgatgac cgataatttt tatgcgccgc cccatagcat cgaggcagag caggcggtga 1344 0 ttggtggatt gcttctggat gatgacagca gtgagcgcgt ccagaaagtt ctggcgatgc 1350 0 tgaagcctga ttcattttac agccgaccac acaaaatcat tttcgaagaa ataaccagaa 1356 0 tgcaccggga gcaaaagcca gtagatggcc tgacgctttt cgatgaactg gagcgtaaat 1362 0 cgttaacggc gtctgttggc ggttttgctt atatcgctga gatcgcaaag aacacgccaa 1368 0 gcgcagcaaa catcgttgcc tatgcaatgc aggttcgtga aaccgcaatg gaacgctacg 1374 0 ccatcaaccg catgactgaa gcgacggaat tgctctattc ccgcaacgga atgactgcaa 1380 0 cgcagaagta cgaagctatt caggcgattt tcacgcaact gacagaccat gcaaaaaccg 1386 0 gatcgcgtcg cggccttcgc tcatttggcg aggtcatgga agactgggtt agcgaccttg 1392 0 agaagcgatt tgacccgtca ggcgaacaac gaggaatgag cacagggatc ccatcgctgg 1398 0 acaggatgct gtcaccgaaa ggtctggtga aaggctctct gtttgtcatt ggcgctcgcc 1404 0 ctaagatggg gaaaacgacg ctatacagcc agatggcaat caattgcgca gtgcatgaga 1410 0 aaaagcccgc tctgatgttc agccttgaaa tgccaggtga tcagatactg gaaaaactgg 1416 0 taggacagaa gtcaggtgtt aacccgaata ttttttacct tccggcgaca aatgacgccg 1422 0 atgacggcta tcagggtgat tacgatggtg acttcaacag ggcgatcgaa acagctaatc 1428 0 gcttgagtga aatcgacctg ctttacatcg acgacacgcc gggattatct ctggctcaaa 1434 0 tcgtcagcga aagccgtcga atcaaacgag aaaaaggatg cgttggcatg attctggtcg 1440 0 attacctgac actaatgacc gctgagaagg ccgatcgcaa cgaccttgct tacggcatga 1446 0 tcaccaaagg actgaagaac cttgccaaag agcttgattg cgttgttgtg cttctgacgc 1452 0 agcttaaccg cgcactggaa agccgaacca ataaacgccc actaccaagt gactcacgag 1458 0 atacagggca gattgaacag gattgcgatt attgggtggg gatccatcgt gaaggtgctt 1464 0 ttgatgacag tgttccacct ggtgaaaccg aactaatcct tcgtctcaat cgtcatggca 1470 0 ataccggcac ggtgtattgc attcaggcaa atggcgctat ttatgacaca gaccaacagt 1476 0 ctgctgaaat gcgccgacgt gaacgcgagg aaccgcagtc caagaagaaa ggaggattct 1482 0 gatgaataaa aaacaattag ccattctcga aaaggcatgg gatgcacaaa tatcatacgc 1488 0 tttgaaagaa caggcactac caataatcca gaccaaatcg aaaatagcca ggcagttatg 1494 0 cgatggcgga ttcctgaacg aaattgagat tacgcgccag atggtaacgt ttaaagggta 1500 0 tgagataaat catcatggta tagcggcgta ttgctcccat cttcctgatg acgttgacat 1506 0 tgatgaaatg gaaagggaga tgaagcaatg accatctaca tcactgagct aataacaggc 1512 0 ctgctggtaa tcgcaggcct ttttatttgg gggagaggga agtgaacgat agctaccgac 1518 0 agtttgaaaa ctggtggtca aaagacaaaa gccagttcac gggagacgat gaattaaaag 1524 0 agtttgcctg ggtgatatgg caggcatcgc gctctgctat tgaactggat atcgactggc 1530 0 ccgaatcgaa tgacgacttt tggaaagatg gtgaagaagg tgcttatgcg atgggttatg 1536 0 aggatgggcg tgacaaaacg gtaattgcag taatgaaagc catcagggcc gcaggaatca 1542 0 aagaaaagaa tttcgattaa gcaaatatca cttcaataaa tcgcttttaa ggcatcacaa 1548 0 tcgctctgta gcgaggtaaa cgcgtgcaag gcatgccaat aagcagcgag aatgaaaaat 1554 0 gcgtcagaat gtgtttgagg aggttttaag aaatgagtac gatagctgag cttgtcaggg 1560 0 ctaattttcg tgaagagttg gtgcgttggt atcggtatcg ttcatcgtcc agtttgccgc 1566 0 ttgatgagtt gtatgagcat tcacctgccg cacgacgcta tccgcgtgac cgtgttcttc 1572 0 gacggttgtt caaactcaac aatgagtttc agcgcaacag aattatccgg agtctggatt 1578 0 taaagtgaag gagtgagcat gagcgaccta tcattaaccc agccaaagct aaaagaatgt 1584 0 ccgttttgcg gcggtaatgc tcgtctgtgg gttgaggccg gaataaatat tgatgtgtgg 1590 0 ggctatgcag aatgtgacct ctgtgaagcc aggggggcat gggcaccatc agttgctgcg 1596 0 gcggctgaaa aatggaaccg gagagcagga gatgaagcaa acctttctgc ttcgcaacga 1602 0 agcaatcaga aataacgcca tagacgccat tctctcacta cccatcgacg acaagtcacc 1608 0 ccacgaagtc cacgttaaag aacccaagcg cagcaaagcg cagaatgacc gtatgtggcc 1614 0 gatgctgaac gatgtttcgc gtcaggtgct atggcatggt caacggctgg cgccggaaga 1620 0 ctggaaagac ctgttcactg ccctgtggct taagaccaaa aaactggagc aacgaagtgt 1626 0 gcctggtatc gacggtggcg ttgtcatgct tggcgtgcgt accagcaaaa tgcggaaggc 1632 0 cagcatgact gagcttatcg aaatcatgtt ctggttcggc tcagagcgca acgtgcggtg 1638 0 gagtgatgac tcccggcgag agtatgaatg gtcacaacga aaaggtaggg ctgcatgact 1644 0 atcaaatcaa atacgccagc acacgacaag gactgctggc aaacgccgct ttggcttttt 1650 0 gatgcactgg atattgagtt tggattctgg ctggattcgg cagcgagcga caaaaatgct 1656 0 ctgtgcgctc actggctaac tgaggccgac gacgcgctca attctgagtg ggtaagccac 1662 0 ggtgcaatct ggaataaccc accgtacagc aatatcaggc cgtgggtgga aaaagccgct 1668 0 gagcagtgca tacaacagcg acagacggta gttatgcttg tgccagagga tatgtcagtc 1674 0 ggatggttca gcaaggctct ggagagtgtt gacgaagttc gcatcatcac tgatggacgg 1680 0 attaatttta tcgaaccatc gacagggctg gagaagaagg gaaacagcaa aggctccatg 1686 0 ctgctgattt ggcgaccgtt catcagtcct cgacgaatgt ttactactgt atccaaagcg 1692 0 gcattgatgg cgatcgggca gggcgtcagg agggcggcat gaggcgacag cgacgaagta 1698 0 tcaccgacat catctgcgaa aactgcaaat accttccaac gaaacgctcc agaaataaac 1704 0 gcaagccaat cccaaaagaa tctgacgtaa aaaccttcaa ttacacggct cacctgtggg 1710 0 atatccggtg gctaagacat cgtgcgagga aaacaaggtg attgacgcga tgatttattc 1716 0 ggggctatat tcctcacgcg ccagcaaaat ctggcgtcgg gattggcgtc ctggatagag 1722 0 accgcgacag atacacgccg cgagcgtgtt ttttattgtc gtatgcacgc gcacatctga 1728 0 attatggtgg gctgtgtggg ggcggagaga tccgcgccgg tcggtttccc ggttacgcca 1734 0 accctgcaca gttcaccacc agacgattgg cgtcgtcggt ggtgagttat taagaaacca 1740 0 ccagagggcg tcattatgac aactcaaatt tctgttgaaa ctctctcccc gatcacccat 1746 0 aaccagattc ctgttattac caccgaactt ttggcgcagc tttacggcac tgagccggtg 1752 0 cgtattcgcc agaatcatca tgagaacaaa gtacgcttcg ttgaagggaa acactttttc 1758 0 aaagttgttg gtaatgacct taaagaattg cgggtagctt taaactactc acaaaatttg 1764 0 cgggttactt taagtaactc acaaaatttg caaccatctt taagagggtt acaaatttcc 1770 0 ccgaaagccc gctccctcat actctggaca gaacgaggcg cagcccgtca cgcaaaaatg 1776 0 ctcgaaactg atcaggcgtg ggatgtgttc gaaaaactgg aagactgcta tttcagccag 1782 0 tgcgagaaaa atactggcaa acaagagaag aagctcaacg ggctttccgc aaaagaaaca 1788 0 gacagccttg tatggctgtg ggattatgcc aaccgctcac aggcattgtt ccgtgagttg 1794 0 tatcccgcat taaaactgat tcagtctggc tattccggca tatgccacga ctacggctat 1800 0 gagttctcgt atatcatcgg gagggcgagg ggcgttttaa ttaatcacac gcgggatata 1806 0 gatatttatg agcctgacgg gccgacgaac cttctggcat gggaaaggct taagaacaaa 1812 0 gagttgccgc cttcactgca tcgctactga caattgacaa cttaacaaac ccagcttcgg 1818 0 ctgggttttt tattgctgaa ttttcaatgt gagaggacat gacaatgaat gagctgataa 1824 0 atagcaatgc catcaaaatg acaagcattg aaatcgctga gttggtggga agccgtcatg 1830 0 acaaggtgaa acaatccatt gaacgactgg cggttcgagg tgtgatccga aatcccccaa 1836 0 tggtggtttt cgaaaaaatc aataacttag gattacttcg tggcgtagag gcttacgttt 1842 0 ttgagggcga acaaggtaag cgcgacagca ttattgtcgt tgcccagttg tcgccggaat 1848 0 tcaccgctcg ccttgttgac cgctggcgag aactcgaagg ggcaaccgcg aaaataccac 1854 0 aaaccttttc tgaggcattg cgccttgcgg ccgaccttga agaccagaag gctgaactgg 1860 0 agaaacagct tgctctcgca gcacctaaag ttgagtttgc cgatcgcgtt ggcgaggcca 1866 0 gcggaatttt gattggaaac tttgcaaagg ttgttggtat tggtccaaac aaactgtttg 1872 0 cgtggatgcg cgatcacaaa atccttattg cttcaggctc ccggcgcaat gtgccaatgc 1878 0 aggaatatat ggatcgtggc tatttcacag tgaaagaaac agcggtcaat acaaatcacg 1884 0 gaatacagat atcgttcacc acaaaaatca ccgggcgtgg tcaacagtgg ctgaccagaa 1890 0 agctgctcga taacggaatg ctgaaagtaa caagggaggc tgcttaatgg ctaaaccagc 1896 0 gcgaaggaaa tgcaaaatat gcaaggaatg gtttcacccg gcattctcaa atcagtggtg 1902 0 gtgctgcccg gaacacggaa ctcaattagc actcgaacga cgaagtaaag aacgcgaaaa 1908 0 agcggaaaaa gcagcagaga agaaacgacg acgagaggag cagaaacaga aagataaact 1914 0 gaagattcga aaactcgcct taaagccccg cagttactgg attaaacaag cccaacaagc 1920 0 cgtaaacgcc ttcatcagag aaagagaccg cgacttacca tgtatctcgt gcggaacgct 1926 0 cacgtctgct cagtgggatg ccggacatta ccggacaact gctgcggcac ctcaactccg 1932 0 atttgatgaa cgcaatattc acaagcaatg cgtggtgtgc aaccagcaca aaagcggaaa 1938 0 tctcgttccg tatcgcgtcg aactgattaa ccgcatcggg caggaagcag tagacgaaat 1944 0 cgaatcgaac cataaccgcc atcgctggac tgtcgaagaa tgcagggcga tcaaggcgaa 1950 0 gtatcagcag aaacttaaag acctgcgaaa cagcagaagt gaggccgcat gacgttcaca 1956 0 gtaaaaacca ttccagacat gctcgttgag gcatatgaaa atcagaccga ggtagccaga 1962 0 atactgaact gtagtcgcaa cacggtcaga aaatacactg gcgataaaga agggaaaaga 1968 0 cacgctatcg tcaacggtgt tcttatggtt caccgcggat ggggtaaaga tactgatgcg 1974 0 tgatatccgg caggttcttg agcgctgggg ggcatgggcg gcaaataact atgaggatgt 1980 0 tacatggtcg cccattgctg ccggatttaa gggactgatc cccgaaaaag taaaatcacg 1986 0 tccacagtgc tgtgacgatg atgcgatggt gatatgcggg tgcatagccc gcctttaccg 1992 0 gaacaatcgc gatctgcatg acttgctggt tgattattac gtgttggggg agacgttcat 1998 0 ggcgttggca cggaaacatg ggtgctctga cacctgtata ggtaaacgcc ttcacaaagc 2004 0 ggaggggatt gttgaaggca tgctgatgat gctgggagtg aggcttgaga tggatcggta 2010 0 tgttgagcgt gaattgccgg gagggagaac ctctgtattt tatcagcgaa aaaatagttt 2016 0 acgatcgtaa aaatctgcat atcatgataa gagtggttac attgccacgc agtcgaaccc 2022 0 gccgatgcgc gggttttttt gtaccccgaa tcctgtgagc tatacggaaa gtacacagaa 2028 0 aggaaggtgc gaccgtaatt aataacaaaa tcttaaaaat cgcatatagc actattagtt 2034 0 ttctaaatat tgtatatttt aagtattgca ggataaccct gtaacgaagt ttgcgtaaca 2040 0 gcattttgct ctacgagttt gccagcctcc cccagtggct ggctttttta tgtccgtagc 2046 0 gtcaaagcag caatggcgct agggcgtcgt gcaattggcg ttgagctgga gagcgggcgt 2052 0 tttgagcaga cggtcaggga agttcagaat gtagtcagtc agaacggatg atattgcagg 2058 0 attagttacg taccgttatt atcctgcgcc cggcccttta gctcagtggt gagagcgagc 2064 0 gactcataat cgccaggtcg ctggttcaaa tccagcaagg gccaccatat cacataccgc 2070 0 cattagctca tcgggacaga gcgccagcct tcgaagctgg ctgcgcgggg ttcgagtcct 2076 0 cgatggcggt ccattatctg cattatgcgt tgttagctca gccggacaga gcaattgcct 2082 0 tctgagcaat cggtcactgg ttcgaatcca gtacaacgcg ccatatttat ttaccaggct 2088 0 cgcttttgcg ggcctttttt atatctgcgc cgggtctggt gctgattact tcagccaaaa 2094 0 ggaacacctg tatatgaagt gtatattatt taaatgggta ctgtgcctgt tactgggttt 2100 0 ttcttcggta tcctattccc gggagtttac gatagacttt tcgacccaac aaagttatgt 2106 0 ctcttcgtta aatagtatac ggacagagat atcgacccct cttgaacata tatctcaggg 2112 0 gaccacatcg gtgtctgtta ttaaccacac cccaccgggc agttattttg ctgtggatat 2118 0 acgagggctt gatgtctatc aggcgcgttt tgaccatctt cgtctgatta ttgagcaaaa 2124 0 taatttatat gtggccgggt tcgttaatac ggcaacaaat actttctacc gtttttcaga 2130 0 ttttacacat atatcagtgc ccggtgtgac aacggtttcc atgacaacgg acagcagtta 2136 0 taccactctg caacgtgtcg cagcgctgga acgttccgga atgcaaatca gtcgtcactc 2142 0 actggtttca tcatatctgg cgttaatgga gttcagtggt aatacaatga ccagagatgc 2148 0 atccagagca gttctgcgtt ttgtcactgt cacagcagaa gccttacgct tcaggcagat 2154 0 acagagagaa tttcgtcagg cactgtctga aactgctcct gtgtatacga tgacgccggg 2160 0 agacgtggac ctcactctga actgggggcg aatcagcaat gtgcttccgg agtatcgggg 2166 0 agaggatggt gtcagagtgg ggagaatatc ctttaataat atatcagcga tactggggac 2172 0 tgtggccgtt atactgaatt gccatcatca gggggcgcgt tctgttcgcg ccgtgaatga 2178 0 agagagtcaa ccagaatgtc agataactgg cgacaggcct gttataaaaa taaacaatac 2184 0 attatgggaa agtaatacag ctgcagcgtt tctgaacaga aagtcacagt ttttatatac 2190 0 aacgggtaaa taaaggagtt aagcatgaag aagatgttta tggcggtttt atttgcatta 2196 0 gcttctgtta atgcaatggc ggcggattgt gctaaaggta aaattgagtt ttccaagtat 2202 0 aatgaggatg acacatttac agtgaaggtt gacgggaaag aatactggac cagtcgctgg 2208 0 aatctgcaac cgttactgca aagtgctcag ttgacaggaa tgactgtcac aatcaaatcc 2214 0 agtacctgtg aatcaggctc cggatttgct gaagtgcagt ttaataatga ctgaggcata 2220 0 acctgattcg tggtatgtgg gtaacaagtg taatctgtgt cacaattcag tcagttgaca 2226 0 gttgcctgtc agactgagca tttgttaaaa aaatttcgca tggtgaatcc ccctgtgtgg 2232 0 aggggcgact ggtgaaaaat ccttgcttgt gattcattat cgacacgggt tcggtggtac 2238 0 caggccgaac tcaccgggag gcacccggca ccatgcagta tacagagatt aggcatatac 2244 0 caaggcctct catagcaggg gcctttttac atgtaaaaaa gcccgagtgg gttcgggcaa 2250 0 ttgcatgaga tactcgtttt aataatcgaa atcattttaa ccaggattca taaggctgcg 2256 0 caactgcgcg gcctttttcg tatttcgggc tgtagtcttc cttctgccat tgtcctgtaa 2262 0 cttccggact tcagcccgct ccttatttta ctcacaatat tatcccggcc gggaggattc 2268 0 atggcattta aacactatga tgttgtcagg gcggcgtcgc cgtcagacct tgcgaaacga 2274 0 ataactcaaa aactgaagga agggtggcag ccttatggta gtgcgctgat ttcgacagct 2280 0 ggttatggtg cggagttcat ccagccagtt gtgagtgagg ggagcatctc atcaccagag 2286 0 gagccaggca accgtccgac gacctcagcg ccttctgttg cgccagaata ttactatgtg 2292 0 atcgcgcttg ctggtcagtc caatggtatg tcatacggtg agggactgcc attgccggat 2298 0 acattcgaca gccctgatcc acgtattaaa cagttagcgc gtcgcagtac ggtgacaccg 2304 0 ggcggtgcag tatgcaaata taacgacatc attccggcgg accattgtct gcatgatgtg 2310 0 caggacatga gccgtcttaa ccatccgaaa gcggacctgt caaaggggca gtacggaacc 2316 0 gtggggcagg ggctgcatat cgccaaaaaa ctgctgccgt ttataccggc gaatgcgggc 2322 0 attctgctgg ttccgtgctg tcgtggtggt tcagcgttca ccaccggagc cgatggcaca 2328 0 tacagtgacg cgagtggtgc ctcggagaat tcaacccgct ggggtgtgga caagccgctg 2334 0 tataaggacc ttatcggtcg aacaaaagca gcactgaaga agaatccgaa aaatgtgctg 2340 0 tttgccgtgg tgtggatgca gggggaattt gattttggcg gtacgccggt aaatcacgcc 2346 0 gcacagtttg gtgcgctggt tgataaattc cgtgcagacc tggcggatat ggcaggccag 2352 0 tgcgtcggtg gctctgctgg cggtgttccc tggatatgcg gggacacgac gtatttctgg 2358 0 aagcagaaga acgaatccac gtaccagacg gtgtatggca gctataaaaa caaaacggaa 2364 0 aagaatatcc atttcgtacc gttcatgacg gatgagaacg gggtgaatgt gccgacgaac 2370 0 aaaccggaag aagacccgga cattccgggt atcggatatt acggttcgaa atggcgtgac 2376 0 agctcagcca cctggacgtc acaggacagg gcgagccatt tcagttcatg ggctcgccgc 2382 0 gggattattt ccgaccgtct ggcaacggcg attttgcgcc atgcgggaag agtggcgcta 2388 0 aacgcggggg catcatcgac agtatcagag gtgcgcccgt catcgccttc cggtgcagaa 2394 0 gccacaggcg tcacaacact gctctcttac cttgccagcg agtcagaggg aagcctgaaa 2400 0 gtacagggat ggtcagccag tggcggcagg gcagaagtgg tcagcgatgc ggagggaacc 2406 0 ggaggtaagg cagtgaagct gaccaaggaa gccggtaaaa gcagctgggt gctggagtac 2412 0 gccgcgggca acggtgcggc tctgttacag aaaggggggc agattcgctg ccgctttaag 2418 0 gtttcgggag cgctggctgc gaaccagtat gttatggcgt tttactggcc ggtatcttca 2424 0 ctgccacagg gcgttgccct gaccggagac ggggggaata acctgctggc agcgttctac 2430 0 atccagacag atgcaaaaga cctgaatgtg atgtaccaca atgcgaaagt gaaccgcccc 2436 0 ggttttcctg gagagtgttt tatctgtgaa ctcaggctgc cagatcatcg tttccgatgg 2442 0 aagcataata agctttttct gcttctgccg gaggagtatg gcccagcctt cccagcaatc 2448 0 gtcgattgtt ataccagtcc acccacgtta gtgtggccag ttccacttct gcacggtttt 2454 0 tccagctctt acggtgtatt acctccgctt tgtaaagacc attgatgctc tcagccatcg 2460 0 cgttgtcata cgagtcgcct gtactccctg ttgatgccag taatccggct tcttttagtc 2466 0 gctccgtata ggccagtgac acatactgag agcctttatc gctgtgatgg atggtgccag 2472 0 acggacgacg ggcccacaac gcctgctcca gcgcatccag cacgaatgtc gtttccatag 2478 0 acgatgagac ccgccacccc acgatgtatc cggcaaacac atcaatgata aacgccacat 2484 0 agacgaagcc ctgccatgtg ctgacgtaag taaaatcagc cacccacagc tggtcaggtc 2490 0 gttctgccac gaactgacgg tttacgcggt cgcctgcggc aacggctttc cggctgatgg 2496 0 tcgtacggac ctttttaccc cggagaacac cggcaagtcc cataaccgcc atgagacgtg 2502 0 ccactgtaca tctggccacc ctgattcctt cccgtaacaa ctgacgccag actttacgca 2508 0 caccgtacac ctgatgattt tcatcgtata cgcgctgtat ctctctcttc agccagtcgt 2514 0 cgtgctgcgc acgggcactg cgtttatccg gatgatgtcg ctgttgctga caatggtaat 2520 0 acgttgacgg ggcaatatgc agttcgctgc ataccggtcc gaccccgtac tgctcacgca 2526 0 gcttatccag cagtggcatc attttttcca gaggcggtcg aactccgcct tcgcaaaata 2532 0 agcggaagcc tggcgaagga tatcgttact gcggcgcagt tcacgatttt cacgttccag 2538 0 ctctttcaga cgctgacgtt cagcgctggt gagcccacca tcaccgcccc cggtatcccg 2544 0 ctcatgctgg cgaacccaga cacgcagagt ctccggcgta cagccaatct ttggggcaat 2550 0 ggaacaaatt gccgcccact gtgagtcata ttcatcctga ctttccagaa ccatacgaat 2556 0 cgcccgctga cggacttcgg gggaaaaacg agtattttta gtcatcctgt ttacctcttt 2562 0 ctcagggagt ttagtctcca ggatttccgg ggcggttcaa aagtggcgac aaacaacctg 2568 0 aaactgggaa cctttggcgc atttgataac gaatggcata cgctggcttt ccgctttgcc 2574 0 gggaataaca gcctgcaggt gacgccggtt attgatggtc aggatggcac accgttcacg 2580 0 ctgacgcagt caccggtcag tgcctttgcg gcggataaac tgcatgtgac agacattacc 2586 0 agaggtgcga cttacccggt actgatagac agcattgcgg tggaagtgaa cagcacagac 2592 0 actgcggcat gataaaaaaa ccgccagcga caggaatgga cgctggcggt ggtgatacct 2598 0 atggagaaaa aataaaggaa cgatactttc gtactctggt ttttaatgaa aacagttctt 2604 0 attgtcaaca ataacggaaa gaaattatga catttctgaa ccagttaatg ctgtacttct 2610 0 gtacggtggt ctgtgtgctg tatctccttt cgggtgggta cagggccatg cgtgacttct 2616 0 ggcgcagaca gattgacaaa agggccgctg agaaaatcag cgccagtcag tcagccggaa 2622 0 gcaaacccga agagccgctc atttagcggc aactttctta atcacacctt tcgacgagaa 2628 0 aatcccatgt cagaaattac atccctggtc actgcagagg cagtgaagga cgtcctgcgc 2634 0 tctgaagaag tccggagcgc actgaaacag aaacttcgcc ataacctgga agcgcgtctt 2640 0 gatgcagaag tggatgccat tctggatgaa ctgcttggtg tacaggcaga gccaccgact 2646 0 gaagcgggag ataccaccgc agagagcggt gaagttcagc ctgaatcacc ggtcgccgat 2652 0 gcgactgaac ctcaacccga atcggtcatg atgctgtaac ggggagtcag ggccatcagt 2658 0 aaacagctgc tggccttttt catgttgtga gcttccggat tgcgggagac ggggtatgta 2664 0 ccagatggaa aaaatcacaa caggtgtgtc atacaccacg tcagcggtgg gaacgggcta 2670 0 ctggttcctg cagttgctgg acagggtttc cccgtctcag tgggcggcaa taggcgtgct 2676 0 ggggagtctg ctgtttgggc tgctgacata tctgacgaac ctgtatttca agattaaaga 2682 0 agaccggcgt aaggcggcac ggggagagta agctgatgag caggaaactc cgctatggtt 2688 0 tatcggctgc cgttctggcg ctgattgccg caggtgcttc tgcgcctgaa atcctcgacc 2694 0 agtttctgga tgaaaaggaa ggtaaccaca ccacagcata ccgtgatggt gcgggtatct 2700 0 ggaccatctg ccgtggagcc acccgggtgg atggtaagcc tgttattcct ggcatgaagc 2706 0 tgtcgaagga aaaatgcgac cgggttaacg ccattgagcg tgataaggcg ctggcatggg 2712 0 tggagaaaaa catcaaagtg ccgctgaccg aaccccagaa agcggggatc gcgtcattct 2718 0 gtccgtacaa cattggtccc ggtaagtgtt tcccgtcgac gttttacaga cgaattaatg 2724 0 caggtgatcg aaaaggtgcc tgcgaagcta ttcgctggtg gattaaggac ggtggcagag 2730 0 actgccgtat tcgttcaaac aactgttacg gtcaggtatc ccgtcgtgac caggagagcg 2736 0 cgctggcgtg ctggggaatc gacagataag aagaatattt tgctgaaaaa tgaggtttgc 2742 0 ttacatggac ggataacacg aaatcctgca aattggcaaa atgtaagtga ataaagtcaa 2748 0 aacagttgtt taacactcag gcaccgtaat gatgcctttg tcatttctgc gcatctcacg 2754 0 cgcatctcac aacacagaac ctttcaggat gacccttgag gataccggtt tggctgtcgg 2760 0 tgcctttctg tgggctggat tcctgtgaga caaggttcat cactaaaagg aaataaccga 2766 0 tgaatatgat ggccgtgccg tttcacggca actctcttta tgtagttaac cataatggcg 2772 0 aaccatacgt tcccatgaaa cctgtcgttg cggggatggg gctggcctgg caatcacagt 2778 0 tggctaagtt aagacagcgt tttgcgtcaa ctataacgga aatcgttatg gttgctgagg 2784 0 atgggaaaca acgcaatatg gtgtccatgc cacttcgaaa acttgccggc tggctacaaa 2790 0 ccattaatcc caacaaagta aaacccgaaa tccgcgataa ggtcatccgg tatcaggaag 2796 0 agtgcgacga tgttctttac gagtactgga cgaagggttt tgtcgttaat ccccgtaaaa 2802 0 tgagcgtgat ggaagaactc aaccaggctt gtgctgacat gaaacgggat aaaaacattg 2808 0 ccagtgtgtt tgctaccggg ctgaatgagt ggaaacaggt taaagccgcg catgtatcaa 2814 0 aaatccgtac gctggtaaat gaagcgaata tgctgattga ttttgtcctg gctgatacag 2820 0 gcaaagggaa aataacaaag gcggattgat ggggtggcta atgatatcag ataaactcat 2826 0 aacgctggtg aagagcctct gtgtacttgt cggcatttca tttttagtca tgctggttgc 2832 0 cattttcttt tccaccgcct ggcgagtcct gacgttatcg ggactggtgg ggtgaaagag 2838 0 agatgaaccg tgttctgtgt gtggtgatta ttgtcctggc ggttggctat ggtgcgctgt 2844 0 ggctggcaac aaaccattac cgtgacaacg cgctcaccta caaagcgcag cgcgataaaa 2850 0 aagccagaga gctggaacag gcgaatgcca ccattactga catgcaggtg cgccagcgtg 2856 0 atgttgctgc gctcgatgca aaatactcga gggagttagc cgatgcgaga gctgaaaatg 2862 0 aaactctgcg tgctgatgtt gccgctggtc gtaagcgcct gcggatcaac gccacctgct 2868 0 ccggtaccgt gcgtgaagcc accggcacct ccggcgtgga taatgcaacc ggcccccgac 2874 0 tggcagacac cgctgaacgg gattatttca tcctcagaga gaggctgatc actatgcaaa 2880 0 aacaactgga aggaacccag aagtatatta atgagcagtg cagatagagt tgcccatatc 2886 0 gatgggcaac tcatgcaatt attgtgagca atacacccgc gcttccagcg gagtataaat 2892 0 gcctaaagta ataaaaccga gcaatccatt tacgaatgtt tgctgggttt ctgttttaac 2898 0 aacattttct gtgccgccac aaattttggc tgcatcgaca gttttcttct gcccaattcc 2904 0 agaaacgaag aaatgatggg tgatggtttc ctttggtgct actgctgtct gtttgttttg 2910 0 aacagtaaac gtctgttgag cacatcctgt aataagcagg gccagcgcag tagcgagtag 2916 0 catttttttc atggtgttat tcccgatgct ttttgaagtt cgcagaatcg tatgtgtaga 2922 0 aaattaaaca aaccctaaac aatgagttga aatttcatat tgttaatatt tattaatgta 2928 0 tgtcaggtgc gatgaatcgt cattgtattc ccggattaac tatgtccaca gccctgacgg 2934 0 ggaacttctc tgcgggagtg tgcggggata atcaaaaacg atgcacaccg ggttttctca 2940 0 tttttcacga gatgggagcg atttcccgcg aagccgcctg tccggtgcgg tggtggaaga 2946 0 aaccggataa aacaaccgca ttgtgcaaat atcgatcaaa tatggtgctg ctgtgtgaaa 2952 0 tctgaaaaat cacagcggtc attatgcatc agtttttaac acaggacgtc agaacgtgac 2958 0 atggcaaagc tggactggaa aaagctggag caggcattcc gacgcgaaca tgccgaaacg 2964 0 ggaataacat tactggactg gtgccggaag aaaaagatta attacaacac cgccagaacc 2970 0 cgtataaaaa tgggcaaaat cgatcatgaa attgatcata aaaccgatca tgaaatcgat 2976 0 catgacatct cagatgaaga accctgcaat gacgcgggtt ccggcgatga aaaatgtgca 2982 0 aaaaactctg aaaaaaactg cgcaaattcg gcagaaacga aacggattcg tggttcccga 2988 0 cttttaccac cttcaaacgc tttttctcag cgaaacaccc acgccgtaag acaccgtgga 2994 0 tatgcgaagt atcttgaggc agataacctc atggatgatg cgtccgacat ggtgctgttc 3000 0 gatgaactgg tgttcacccg ggcccgcgca ctttcagtaa ctaaggcact taaagggatg 3006 0 ttcgccgacc tggaagaggc aactgacgtg gaaacccgtg ttgctcttta cgacaaaata 3012 0 ctcaaagctg aacaggccct tgaccggaat attgcccgta tcgagtcaat tgaacgctca 3018 0 ttgctgacgc tggacgtcct ggctgagaca gcaccaaaac ttcgtgctga ccgggaaaga 3024 0 atcaacgccg ccagagataa actcagagct gaaaccgata ttctgaccaa ccagcgtcgg 3030 0 ggcgttgtta cgcctgtcag tgacatcgtg tcatcgctgc atgaaatgag taattcgggg 3036 0 agactggatg acattccgga agaatgaacc gcgatgtgat gagccgtcag aaatgaccga 3042 0 ggctgaacaa cgtctgttca tcatgactaa actgagcaat ccctggtggc ggctcaatca 3048 0 tctctacaaa atacagaacg aaaaaggtga actggtcacc ttcagaatgc gaccggcgca 3054 0 gcgccagttg ttccggagca tgcacaataa aaatattatc ctgaaagcgc gccagctggg 3060 0 attttccaca gccattgata tttatcttct cgaccaggca ttattcattc cgcatctcaa 3066 0 atgcgggatc gtcgctcagg ataaacaggc tgccagtgaa attttccgca caaaaattgc 3072 0 tgtaccgttt gatcatctcc ctgactggct gagagcctca ttcaccatcg ttgaacgtcg 3078 0 tagcggtgcc agcggtggct atatcctgtt tggtcacggc tcgagtatcc aggtggcaac 3084 0 ctcattccgt tcaggtacgg tgcagcgcct gcatatctca gagcacggca aaatttgcgc 3090 0 gaaatatccg gctaaggcga aagaactgcg aaccggtacg cttaatgccg tctctgatga 3096 0 atgcattatt tttgatgagt ccactgctga aggcgtgggt ggtgattttt acgagatgag 3102 0 taaccgagca caggagatca ctgcatcagg cttattgctg acggcacagg attataaatt 3108 0 ccatttttac gcctggtggc aggatcctaa atacagcgcc agagtgccgg aaagcgggct 3114 0 gaagctgtca cgggaaaaaa tgacgtattt ttctgcggtt gagaaggcaa tgaacatcac 3120 0 gcttactgat gaacagaagc agtggtacat caataaggaa actgaacagc gtgaggaaat 3126 0 gaagcaggag tttccctcaa cgccacagga ggcgtttctg acgtccggac gacgtgtgtt 3132 0 cagtgccgaa agtacgttgc aggcagaatc attctgttcg ccaccgatga ttgtttatga 3138 0 cattgaacct gttacaggag cgaagactaa agctcagtct ctgcgtgaag gaaataaaaa 3144 0 cgagttgcag cggacgctga tgaattatct gctggtatgg gaactgccgg atccggatga 3150 0 agagtatgtt tgtggggcag atactgccga agggctggag cacggagacc gctcatcgct 3156 0 ggatgttgtc aaacgcagta atggcgagca ggtggctcac tggttcgggc atctcgatgc 3162 0 tgaacttttt gctcatctca tttcgcaggt ctgtcgtatg tataacaacg cgtttgtggg 3168 0 gccggagcgt aataatcacg gacatgcagt tatcctgaaa ctccgggaac tctatccgac 3174 0 acgttatatc tacaacgaac agcatcttga ccaggcatat gacgacgata cgccccgcct 3180 0 tggctggctg acaacccgtc agagcaaacc tgttctgacc gaaggaatga aaacgcttct 3186 0 gaataatgga atatcaggga tccgctggtc aggcacatta tcggaaatga acacctacgt 3192 0 ttatgacgcg aaaggctcca tgaatgcaca ggaaggctgc tttgatgatc agctcatgag 3198 0 ctacatgatt gcccaggaga tgcgcgccag aatgccggtg agggtaaaac agaaaacgga 3204 0 taaacgcaga accacacact ggatggctca ctgatgaaaa atgaaactaa caccatggcg 3210 0 acgaaaaacg acaatggagc cacgccgcgt ttttctcagc gccagttaca ggcgctttgt 3216 0 tctgatattg acagccagcc taaatggcgt gatgccgcaa acaaggcctg tgcgtattac 3222 0 gatggcgatc agttgccacc ggaagttctt caggtactga aagatcgcgg tcagccgatg 3228 0 actatccata acctcatcgc gcctaccgtc gatggcgttc tgggaatgga ggccaaaaca 3234 0 cggactgatc tggtggtgat gtcagacgag ccagatgatg aaactgaaaa actggctgaa 3240 0 gctattaatg ctgaatttgc cgatgcatgc cgccttggca atatgaataa agcccgctct 3246 0 gatgcctatg cggaacaaat caaggcgggc ctcagttggg tggaggtcag acgaaacagc 3252 0 gatccgttcg ggcctgaatt taaggtgtct actgtcagcc ggaatgaggt tttctgggac 3258 0 tggctgagcc gggaggctga tttaagtgac tgccgatggc tgatgcgtcg ccgctggatg 3264 0 gataccgatg aggcaaaagc tacattcccg ggaatggctc aggttatcga ttatgccatt 3270 0 gatgactggc gtggttttgt cgataccacg gttactgaag gccagcccag tccgttgatg 3276 0 agtgcatggg aagagtatca gtcatgggat cgacagcaga acgaatggct tcagcgtgaa 3282 0 cgccgtcgtg tgctgcttca ggtggtttat taccgtacat tcgagcgtct tccggtgatt 3288 0 gaactcagta atggacgggt ggtggccttt gataaaaata atctgatgca ggcggtagct 3294 0 gtggcatccg ggcgggttca ggtgaaagtc gggcgggtaa gccgtattcg tgaagcctgg 3300 0 tttgtcgggc cacactttat tgtggatcgc ccctgtagtg ctccgcaggg gatgtttccg 3306 0 ctggttcctt tctggggata ccgaaaggat aaaaccgggg agccatacgg gctaatttcc 3312 0 cgcgccattc cggcacagga tgaggtgaat tttcgtcgta tcaagctgac ctggttgctt 3318 0 caggccaaac gcgtgattat ggacgaggat gccacccagt tgtcagacaa cgacctgatg 3324 0 gagcagatcg aacgtccgga tggcattatt aaactgaatc cggtccgaaa aaatcagaaa 3330 0 agtgtcgcag atgtttttcg ggttgagcag gattttcagg ttgccagcca gcagtttcag 3336 0 gtcatgcagg aatcggaaaa acttatccag gataccatgg gagtgtattc cgcatttctc 3342 0 gggcaggatt caggtgcgac gtcaggcgtg gctatcagta acctggtgga gcagggggcc 3348 0 acaacccttg cggaaatcaa cgataactac cagtttgcct gccagcaggt gggaagactg 3354 0 ttgctggctt atcttctcga tgacctgaaa aaacgccgta atcatgcagt ggtgattaat 3360 0 cgcgatgatc gccagcgtcg ccagaccatt gtcctcaatg ctgaaggtga taatggtgaa 3366 0 ctgaccaatg atatttcaag gttaaataca catattgcgc tggcgcctgt tcagcagaca 3372 0 ccggcgttta aggcacagct tgcacagaga atgtcagagg ttattcaggg gctgccgcct 3378 0 caggtgcagg ctgttgtgct cgacctgtgg gttaatcttc tggatgtgcc gcagaaacag 3384 0 gagtttgttg agcgtattcg tgctgcgctg gggacgccaa aatcaccgga tgaaatgacg 3390 0 ccggaagaac aggaagtagc ggcacaacaa caggcacttc agcaacaaca ggcagaactc 3396 0 cagatgcgcg agatggctgg cagagtggca aaactggaag ctgacgccgc cagggcacat 3402 0 gcagctgcac aacgggataa tgccagtgca cagcgggaag tcgccctgac acaggggcag 3408 0 cgttatgtgg atgcgcttaa ccaggcacat acggcagaaa tcattaccgg cgtacagaat 3414 0 atggaacagg agcaggacgt tcttcagcaa cagatgctgt atacgttaca acagcggatg 3420 0 aatgaaatgt cgctctgaaa actctggctt caactgaacc ccgtcatcgt acggggtttt 3426 0 ttgtttccgg aggtaagcgt tccgggagcg gtgcgcttat tcgcgggggc agcgataagc 3432 0 cttatttact caaccattcg gatctgtccg ataaacagac catgcggagt tatttatgga 3438 0 ttttgaattt acgggtgaag aaaccccgga acaactggaa aaaatgctgg aaggacttgg 3444 0 ggatgtggat attgacagtc acgcacagga cgtcgtgacg gaagatacca cggaaaaaca 3450 0 tgcggatgag gaagcacaga ctcagacggg cgataacaat gtggcaccga cgccggatgc 3456 0 cagtgtggag cagacgcagg acgtgaagga gccggaagcg aagggggtgc tcacccgcga 3462 0 cggtaaacac gtcattccct atgaagtcct tgaggctgaa cgttccggta agcaacgggc 3468 0 cgaacaggaa gccgcacttc ttcgtgggca gatagctgaa gaaaaacgca gggtggaact 3474 0 gctgacgtct cagatccacc aggccggtat gaagcccaca ccgttaccgg aaaacgaaaa 3480 0 aatttctgat gagcagattg cccgtatcag ggagatgtat ccggaaattg gtgacgcggt 3486 0 ggcttcgctc atccgtaaaa ataactatct ccagtcccgt gttcagcaat cagcacagca 3492 0 ggcagaaggt aatggtggtg aggatttatc accggttctt gatgcgatga atgccgtgcc 3498 0 ggtgctgaaa acgtggcagg agtccgatcc agatcgcttc tcggttgctg tatccatcga 3504 0 cgggaagctc cagaatgacc ccgcatggaa agacaaaacg ctcactgaac gtttcgctga 3510 0 agtggcccgt cgtacgcagg ttgctttcgg tgaagtcagt gagtcgtctg ctgacaacaa 3516 0 ggcagacaaa acggatatcc ggaaaacggc ggaagagaaa gtgaagaccg ctgaacagga 3522 0 gcaggcagta cctgcttccc cgtcagattt aggcaccacg gcttccgtcg gaaccggtga 3528 0 taattttgaa cggttacttg gcgcttctca ttcagaggca gaggcgatta tgcgcggtat 3534 0 gacgaatgct gaaatagacg cgcttctgga gaagctcggg taacttactg aaggagaact 3540 0 gaagtaatga cgactgtaac atcagcccag gcgaataagc tgtatcaggt ggcgcttttt 3546 0 accgctgcca accgcaaccg ctcgatggta aatatcctca ctgaacagca ggaagcgcca 3552 0 aaagcggttt cgccggacaa gaaaagcacg aagcagacca gcgcgggtgc gccggttgtc 3558 0 cgtatcacag accttaacaa acaggccggt gatgaagtga ccttcagcat catgcacaaa 3564 0 ctctcaaaac gtccgacgat gggagatgag cgtgttgaag gtcgtggtga ggatctcagc 3570 0 catgctgact tctccctgaa aatcaatcag ggacgtcacc tggtggatgc aggcggacgt 3576 0 atgagtcagc agcgcacgaa gtttaacctg gcatcctcag ccagaacgct tctggggacg 3582 0 tactttaatg acctgcagga ccagtgtgcg atagtgcatc ttgctggagc tcgtggtgat 3588 0 tttgttgctg acgacactat tctgccgaca gcggagcacc ctgaattcaa aaaaatcatg 3594 0 atcaacgatg tactgcctcc gacacatgac cgtcactttt ttggcggtga tgcgacaagc 3600 0 tttgagcaga ttgaagcggc agatattttt tctattggcc tggtggacaa tctctccctg 3606 0 ttcattgacg aaatggcgca tccgttacag ccggttcgtc tgtccggtga tgaacttcac 3612 0 ggagaagatc catattacgt cctgtacgtc acgccgcgtc agtggaatga ctggtacacc 3618 0 tcgacgtccg gtaaggactg gaaccagatg atggttcgtg ccgtgaaccg tgcaaaaggt 3624 0 tttaatcatc cgctgttcaa aggtgaatgt gcgatgtggc gcaatatcct ggttcgtaag 3630 0 tatgcgggta tgccgatccg tttctatcag gggtcaaagg ttctggtatc agagaataac 3636 0 ctgacggcaa ccacgaaaga ggtcgctgct gcaaccaata ttgaccgcgc catgttactg 3642 0 ggggctcagg cgctggcaaa tgcttacggt cagaaggcgg gcggtcactt caacatggtt 3648 0 gagaagaaaa cggatatgga taaccgtact gagatagcaa tcagctggat caacggtctg 3654 0 aaaaaaatcc gtttccccga gaagagcggc aagatgcagg atcacggcgt gattgccgtt 3660 0 gatacagcag tgaagctctg attttttcct ttccctatgc cgggttttcg cccggctttt 3666 0 tcaggagtca ttaattatgg caaagactat ccttgccccg tcactgagtg aacgggtcta 3672 0 tacgggtacg cacggtaatg agtcggtggc agaaggcgta tttacggtga atgctgcgga 3678 0 agcggacagt gttattcatc ttctctcact gccagtgggc atccgtatca actcactcca 3684 0 actggtttca acgggtggtc tgggtactgc aaccgtcagc attaagtccg gtgagcatgc 3690 0 tctcatcgat aacagcgaag ctgtttctgc aaaatttgcc agatatgtgc cagtggagcc 3696 0 gtacaccaca cagcgtgacg gggagctggt tactgtcacc attaagactg ccgctgcaac 3702 0 cggcaccctg aatgttctgc tgcgttatac cgtggtggga tactgattaa aaccttccgg 3708 0 cccgcgtcat gcgggctttt tatccgggga attatatgag tgagaaaatt gccgttgtct 3714 0 atatcggccc aaaacccgtg aaaaaggaca ccattaccgg aagtcgcacg ctgttcccac 3720 0 gtcttgagcc ggtgcatgtt gacagcgcga tggcctggca actgctgggg tttccggatg 3726 0 tctgggttcg tcatgaagag cttgatgatg ttctgaaaaa gcaacaacag aatgagcagt 3732 0 tgcggcaggc acagcaggcg caggaaagag tgcttgctgc gctggcagaa gcggagaaca 3738 0 gttttgttgt ttctgttaac gggcaggagg tggatttaag taagctcacc tcagcacggc 3744 0 tggcgacgct gtgtgaggca gaagagctgg atattcacaa agacccgaaa gaaacggctg 3750 0 aggcattccg tatccgggtg cgtgaggcat ttcgccgtcg tgttgcggag actgaacagc 3756 0 atggcggaac tgagtgattt tttaccgtat gtccgtcgtc atatcagcgg tccactgaac 3762 0 attatgatga cggatgctct gtcaatggct gccgtggcat tcagccgcca gtcgttggtg 3768 0 tgccgtcggg aggttactgt tgtaccagta gcaggaaaag aaatcgtgct tccgtatgac 3774 0 aaagatgatg aggagtgcgt tcatatcatc cgtatctctg acgataatca tgagcttttt 3780 0 gtcggtcggg atgtggatat cagctccgga cgctccctgc gatttgcctg ttctcccggt 3786 0 gaggtgagcg tgctttatgc cgtcgctccg aaagccggac gcagccagat accggatgaa 3792 0 ctcctcacat ggcctgaaga agtggctgcg ggggcacttg agcggttgtt catgcagact 3798 0 ggtgtttcat ggtcagatcc gttacgcgca cagtattttt ctgtgcagtt ttctgagggg 3804 0 atccgtcggg catatcgtca tacactggcg acaagcccgt actcttcata ccgcaaccct 3810 0 gtacgcaggc agaggttttt ctgatgacga cgattacaga aatcatcgga cgtgtgaata 3816 0 cacaactggt tgacccgatg atggttcgct ggcccctgca ggaattgtgc gattattaca 3822 0 atgatgctgt gagggcagtg attctggcga gaccggatgc tggcgcaagc ctggaaacaa 3828 0 taagttgtgt tcctggcgcc cgtcaggttt tgcccgatgg tgtaatacaa cttcttgacg 3834 0 tgatatgcct cagtgacggt agtgcagtca gaccattatc ccgggaggtg ctggatgcgc 3840 0 agtatcctga gtggcccaca atgaagggta ttcctgaatg ttttatcagc aacgacctgt 3846 0 ccccgcgcgt attctggctg tttcctgctc ctgacaaaga gataagtatt gatgcagtgg 3852 0 taagccggat accggaggca gtgtatgttc tgacgcagga cgatgatacg ccagttccac 3858 0 tggaagaggc ttatgttaac ccactggtgg agtggatgtt gtttcgcgct ttcagtaagg 3864 0 atgctgccgg tggcgcagaa tcggggctgg ctgcgcagca ttatcagagt tttgttgagc 3870 0 aacttgggat caaacagggg gcagacagtg cattgtatgc ccgtaaaaaa gtgtttaacg 3876 0 gaggtggagt gtgagtgttg ttgtttcggg gacgctgaaa tctcctgatg gtgaggcgat 3882 0 atcaggagca aatattaccc tgacggcgct gacagtttca ccggatgcgc tcagcggcac 3888 0 cagtgcgtcg gcagtgaccc gtgaaggtgg atattacgga atgacgatgg atccggggga 3894 0 gtatgcggtt tcggtgacgg tgaaagggaa gactgctgtc tacggacgtg tgcgtattga 3900 0 ggggaccgaa agtacggtga cgctcaatat gctgttacgc cgcagtcttg ttgaggttag 3906 0 catacccgga gaactgctga cagatttccg gcagatacag aataatgtgg ctgatgacct 3912 0 tgccactatt cgtcgcctga atgaagacac ggcgacaaaa aacactcagg ccacacagtc 3918 0 aaaagaaagt gcagcagcca gtgcgaagag tgcatctgac agtgcaaaga cggcaaccag 3924 0 cagggcggct gaagccggac aaaaagcgac tgatgccact gaggctgcga cccgtgcagt 3930 0 cacagcagcg gggaatgcag aggaaagctc gacccgtgcc ggagagtctg aaaaagccgc 3936 0 cggagctgat gcagaaaaag ccagacagca tgctgaaaag gccaggctgg cgcaggagag 3942 0 cgccggagag atccttaagc gggcagaggc tgccactgtc agtgctgaag aggccagacg 3948 0 tatggctgag aatgcacggg ggccccgggg gcctcaggga gaaactggtc cgaaggggga 3954 0 tgtcggtcct aaaggcgaaa caggtccagt gggccctcaa gggcccgcag ggccgaaagg 3960 0 tgagcgtggt gacgttggtg ctcagggggc tgtagggcct gctggtccgc gtggtgagaa 3966 0 gggcgaacag ggggagcgag gaccgcaggg aataccaggc ctgaaggggg ataccggaga 3972 0 gcgggggcct aaaggggacc agggggatat ggggccaaaa ggcgagaaag gtgatccggg 3978 0 aggtcctgca ggcccgcaag gtcctaaagg cgaacgagga gaagccggac cacagggacc 3984 0 gatgggagca cgaggtgagc gtggggagac tggcccccga ggtgaacctg gtcctgcagg 3990 0 tccgagaggc gaacgaggag agaccggacc tcagggacct cgtggagagc caggtccggc 3996 0 aggcagcgct gcaaatgtgg ctgatgcaac gacggcacag aagggaattg tgcagttaag 4002 0 cagcgcaacg gacagtgatg atgaaacgaa ggctgccacc ccgaaagcgg tgaaagcggc 4008 0 aatggatgtg gcaaatgaag cgaaaacaaa ggcagaagag gctgcagcag gaggtggtgt 4014 0 tcccggtccg aaaggagata aaggggacac ggggccagca ggtccggctg ggccgaaggg 4020 0 tgataaggga gagcgcggtg acaccggccc tgtcggggca accggcgaac ggggaccggc 4026 0 aggtgatgct ggtccggcag gcccgcaggg gccgaaaggt gacaggggag agcggggaga 4032 0 gaccggtctg acgggaaatg caggtccaca gggtccaaag ggagataccg gtgcggcagg 4038 0 cccggcaggc ccacagggac cgaaaggaga aacaggtgcg gcaggcccgg tgggggcgac 4044 0 cggacctcag gggccgaagg gcgacccggg ggagacgcaa atacggttcc gtctggggcc 4050 0 gggaaacatt attgagacaa acagccatgg ctggttcccg gatacagatg gcgcactcat 4056 0 caccggactg acctttcttg accccaaaga tgccacacgg gttcagggtt tttttcagca 4062 0 tttgcaggtc aggtttggtg acgggccgtg gcaggatgtc aaggggctgg atgaagtggg 4068 0 cagtgataca ggcagaacag gagaatgaca tgaatatttt gagaaagctt atgcagagtc 4074 0 tgtgcggttg cggaaagcat gatgactgtg aaaacgggca gtcgcttaca gcacaactgc 4080 0 gactgggacc ggcagacatt ctggagtcag atgagaatgg cattattccg gagcaggaca 4086 0 gggtaatcac acaggtggtg atactggatg cagataaaaa gcagatacag tgtgtggtaa 4092 0 gaccgctgca aatcctgcgt gctgacggga cgtgggaaaa tattggcggg atgaaatagc 4098 0 cgacagcttc acaaaaaccg gagcccggct ccggtttttg ttgtcatgta tagggggggg 4104 0 ttattagaga gtgaagtaat aaacatgtta atacgatgga gtgaaggatg ccgtgtaatt 4110 0 ctggttcaag agttttttat gccggaaaat cgcaggatta ttctggatag taaagaatcc 4116 0 tggttaataa tctgtgatag tcagttgggc catttaatgc gcagtatgta tcagggacgc 4122 0 cgttttattc agctgaatct ggaaaaattg aaaggggtac atgatgtcgc cttgccagtg 4128 0 aaatgggaat tcacacgaag acagtgaata gctttctgta tacgggaatg gcgaaaaatg 4134 0 gactgtatgg tgtgagtgtg aaacatcttg cgtgtgcgga gtgatgcttc tcgttgctac 4140 0 agcggcaatg ataatgcagt gaaaaaaggg gagcaatatg ctcccccaaa ccgaaagaaa 4146 0 attgcaataa tcaatgaagt tatttagtca tcatcagaat gtcatgcaag gcattttgtt 4152 0 tcagtgatgc cgatcgcgat tttagcgaat tccatcataa atcccctgat ttttaagcct 4158 0 gaagcagtca aaggaatttc tatgccctat atcgatatca ccacgatgcg tgggatgatg 4164 0 ccgcgcgttg tgacatccat gctgcccgag cattccgctg tactggcgga ggactgccat 4170 0 ttccggtttg gtgttattac accagaacgt cagatatccg gggttgagaa aacattcaca 4176 0 attaagccaa aaacaatttt tcattaccgt gacgatttct ggtttgcatg gccggatgtg 4182 0 gtggatgtga tccgcagtcc gatcgctcag gacccccacg ggcgtattta ctacactgac 4188 0 gggcgttttc ctaaagtgac ggatgcgact attgccacaa aaggggacgg gaatcacccg 4194 0 acatcatcgt atcgtctggg gatccccgcg ccgacgacag ctcctgtctg tactgttcag 4200 0 cagggcggtg atgtttctga cgataacccg aatgatgatg aaacccggtt ttatacggaa 4206 0 acctttgtct cagattatgg tgaagaaggt ccgccaggtc cggcgtctct ggaggtaaca 4212 0 ctccgtactc cgggaactgc ggtacaactg acgctggctc cggtgccatt gcagaatgcc 4218 0 agtattaaac gtcgccggat ttatcgctct gcatcaggtg gaggggaggc ggatttttta 4224 0 cttgtggctg aactggatgc atccgtgctc agttacacgg acaaaatacc ggcgaaaaac 4230 0 cttgggcctt ccctggcgac atgggattac ctgccgccgc cagagaatat gacaggcctt 4236 0 tgcctgatgg ctaacggtat tgccgccggg tttgccggta atgaagtgat gttttcggaa 4242 0 gcgtatctgc cgtatgcatg gccggaagtg aatcgtcaca cgacggcaga agatattgta 4248 0 gctatctgtc cgctgggaac gtcactggtg gtggcgacaa agggggagcc ttatttgttc 4254 0 agtggggtat caccgtccac aatttctggt tccaaaatcc cttcaatgca ggcgtgtctg 4260 0 agcaggcgga gtatggttgc gatggagggt tttgtgctgt atgcaggaac aaatggcctg 4266 0 gtgtctgttg atgcaaacgg taatgtcgcg ctggcgacgg aacagattgt ttcaccggaa 4272 0 cagtggcaga gtcagtttaa tccggcctcc attgtggctt atccctggcg tggtgaatac 4278 0 attgcctgtt acacgaaacc ggatggtaag caggatgtgt ttgtattcag tccggtgaac 4284 0 atggatatcc gttatctcag tacaccgttt gactgcgcat gggttgatct cgcgaaagat 4290 0 atgatgcgcg tggtgacagg agacaaaatg tcagtgcttg ccgggggggc tctgccctcc 4296 0 acgataaggt ggcattcaaa aattttttca ttacctgaaa gaacctcttt ttcctgtatc 4302 0 agggtgaaat ctccggcgcc tgagcgggtg gggatcacca ttatggctga tgatgttcct 4308 0 gtgattcatt ttgcgccggg tacgtttaag ggaagtgtgg tgagacttcc ggcagcaacc 4314 0 gggcaaaact ggcaggtgat ggtatccgga ttcgggcagg tggaacgaat aaccctgagt 4320 0 acatcaatgt cggagatgcc ggtatgacca gaaaaccgtg gcgtgcgggg aaggatttat 4326 0 ccactgttgt ggagaatatg gaaattggca ccgggcagcg tggtgacgga cgtcacgcat 4332 0 ttgtgacccg tgaggaactg gttggtctta aactcgcccg gcgtcgaaca tcgggtggtg 4338 0 cctcatatgc actgaatccg ggtattgaga ttgacagtac tttaatgact gttgattttc 4344 0 ccacaaaacc gctgaatttt aaggcgaccg gtggatttgg ctcggttctt cttgaatggg 4350 0 atatgcctaa ttatcgcgga cattcactga ctgaaatctg gcggggtacg gaggatgacc 4356 0 ttgctgatgc agtgctggtt gccacgacgc cggggcaggt ttacggcgat ccggttgacc 4362 0 ctggctggtc gggattttac tggatacgtt ttgttaacgc ggcaggagtg aaaggtccat 4368 0 ggaatgctga aaaaggcact caggcacaaa cacagatcgg cgtgaaggcc atcattgacc 4374 0 agatccgcga tgaggctgca aagtcgccgg ttgtgtccga gctgcgtaaa gaaataaaaa 4380 0 acgcgcaggg gcaggctgta aaggatgctg caattaagac aaccgaagtt gtagggactc 4386 0 tcagggaaga aacgacaaga acgattggtg gtattgaaac ccgcattagc acactggatt 4392 0 cgtcaaccag tgaatcgctt aatgaggtcg acaagcgcat cactaaattg gataaagaag 4398 0 gcggtgaagc ttttcttgca atgtggtcaa aaaaagcggg agttgatggt atcactgcgg 4404 0 ggatcgggat tgtcgccgga aaagacagtg aaggcaggcc tgtaagtcag gttgcaattt 4410 0 ctgcgtcgca gttgtttgtc tttgacccga ataatccgga taacacagcc tatccgtttg 4416 0 cggtatcagg tggcaaggta gtgatcccga aagcgatgat ttatgacgcg gtgattgaaa 4422 0 cactggtgtc gcggaaggtt gtggcggatg aggtaaaagc cggggtaagt atcacttcgc 4428 0 cagttatccg gagtgccgtt attcagaacg gaaactttca ggttgattct cagggtaacc 4434 0 tgaatattgg aggccttttc agtgttacgt cacaagggca actgacaatt cgttactcta 4440 0 atcagaatgt aggactggtg atccgcaatg ataaaattga ggtttatgac cagaatggac 4446 0 gactggctgt tcgcataggc agattacgct gatcaggagg tgagtattgg aatacggttt 4452 0 tgccatttat aacagaaata acgttaatgt tacgggcgtg ctgactccag tatttttcct 4458 0 ggacagattt acagcggagt ctggctcaaa gacgtacact aataaacccg acgggaaatc 4464 0 attgcaggct gtatgttgtt tatttccctg gaataatgta tttgcggatc ggaaagtacc 4470 0 gaagataacc attaatgaca atacggtgac gtggtcgaat cttgagcagg gtatgggatc 4476 0 ttatatttat acattctggg gataagtgtt atgtacggtt tgagcattat gaagccggat 4482 0 ggcagcgtat ggataagtcc aggttttacg ccgcagtgtc tgatcaacaa aggcaccata 4488 0 ccggcgactg aaaagtcttt ttttaaaaca tcaatcccgt caggcaaaag ttgttttttc 4494 0 tttatcagaa cagagaagaa ggccgatgtc atgtacacgc atgaacagat tgatggatat 4500 0 catgcactaa ggcttcatgt aattgtcagg ggaacgaacc ctggtgttac gacggtttat 4506 0 gctttcgcga atatggttac tccaccttct gagtatggta tcgccatgta taacccggac 4512 0 ggtgagatga tttatcatgg cgaaatgatg ctgcttgacg cgaagttaat acctgttgat 4518 0 atcaaatttg aaaaggacct tggatatcca tgcgcaatca tgcctgcact ggtcgggtat 4524 0 tataactgga aaagaactcc ttatgatcga ccgatttata ccacatccac tggtgctaca 4530 0 ggaaataaaa tatattcctg tgagcattat tccggtggtg caacatggga tattcgaaag 4536 0 ccgtatatag ataaggtcct ggttattaat acatcagtat atgattagtt gaagcgagtc 4542 0 tttaatattc atttaaaatg tctaaaaaga tgtattatta aaaagtttag cgtgttatct 4548 0 gaatacagga tatcttaaat gaagagtata gcaacactgg ttgtgtgtgc aatctccggg 4554 0 attgcctgtg taaatttatc tgcacatgca gcagaaggag agcatacaat ttctctgggg 4560 0 tatgcgcact ttcagtttcc gggactgaag gattttgtaa aggatgcgac tgctcataac 4566 0 agggagactt tcagtcattt cgtcaacaga aactactttt cttcattggg cgaatataca 4572 0 gatggtcggg tcagtggata tgaaggcaag gataaaaatc cacagggcat taatatcagg 4578 0 tatcgctacg agataacgga tgattttggc gttatcacct cttttacatg gacgcgttct 4584 0 ctcactaact cacagacatt tattgatgtg cagtcagccg atcataccag gaagattaag 4590 0 aatccggcag cttctgccag aacggatatc agggcgaatt actggagtct gttagcgggg 4596 0 ccttcatggc gggttaatca gtacatgagt ttatatgcga tggcagggat gggcgttgct 4602 0 aaagttagcg ctgacctgaa aattaaggac aatattaaca gtagtggcgg attttctgaa 4608 0 agcaacagca cgaaaaaaac ctcccttgcg tgggctgcag gtgcacagtt taacctgaat 4614 0 gagagtgtta cactggatgt ggcttacgaa ggttccggct ctggcgactg gcgcacgagt 4620 0 ggcgttactg ctggcattgg cctgaaattc tgacctgtat ccggtaaccg tttactaccc 4626 0 gctgtgatgg cgggtttttt attgcccgta cagggcaaaa accgtaaatt atgcgtgggt 4632 0 gcctttcggc tgatggctgg agggtgaacc tgaaggcctg atgtggaaag gccccgagtc 4638 0 aacttaacgt taacccgagg ccctaacact tcgtacctta agcaagtaga aggttagcgc 4644 0 ctctctgtaa aaggagtcaa gcgctatgtc gcaaaaatcg cttatcaccg tcacaatttg 4650 0 catgacggtt atcttcacca tctggatgtt gcacggttca ctgtgtgagt tccggctgaa 4656 0 tttgtgggga gcggagtttg cggcgttctt acagtgtaag cagtaggaaa accgcgacgg 4662 0 ggacgagagt ccccgtcaac tggttgctga ggttcagccg atatggcacc cgtttcaggt 4668 0 gagagaatga acgataaaat tctctggtat atgcagcgtg ttgtgagaaa ttcccgcaac 4674 0 cctgaattta tgaatgaagt taaagacgcc tgccttaaaa agcaggcgtt ttgttttgag 4680 0 gcacctgatg gctttttggt gctgcgttct gtgctcagtg ctgatggtat cccttatgtt 4686 0 ctggtgttgc tgggcgtgtg tacggggagt aacagcgttg agcgttacct gccggaggtg 4692 0 aagacattaa cccatctggc tggcggacgc tgggctgagt tccatacggc aaggcgggga 4698 0 tttatccggc tgggaaaacg actgggcttt gagcgaatgc cggatgatga ggatggcttc 4704 0 atggtgttca ggatagcggt ctgactgcta cagttttcat cattgtgttt aaaccaacat 4710 0 tgtaattcac attctgaccc tgctccggca gggttttttg ttatccaggg ggccattatg 4716 0 ggtggaagta aaggcggtgg tgataccaaa gtaaaaccaa cagcagcgca aatagcacag 4722 0 gaagaagtgg cctggaaagg gtggcaggat tacaaaaata tcctccgccc ggctgaagat 4728 0 aacttcatgg aaaaggtcga tgacctgaac agtgagcagc agtacgacaa tattgctggc 4734 0 accacaaatc tggggtatca gaaacagttt ggcgaagcac ggaaggagct tgcgggtaat 4740 0 cttgctcagt ccggcgttga cccatccagt ggtcgtttta atgcggtaat gaatgcgaac 4746 0 cagagtgacc aggtaaccgg gcagattgac acaaccacac gggggcaggt atcgcaggca 4752 0 gataagtatg ttgccgggct acaggatgtt gctgctctcg gttctggtca gaaggcggat 4758 0 gcgttacaga gttttaactc tctggcagac agcagtctgg caaaagctaa atcggatgca 4764 0 caggcggcgt ttacgaaaca gcaggggcga gcctctcttg ttggcgctgg tctgggtgcg 4770 0 gcaggtgcat atgcgatgca taaggctggc ggtagcggag gaagtggcgg tgctaaaaca 4776 0 cctggcaccg gcgctaatgc cattcagcat caggctcaga actggagact gtaattatgg 4782 0 agtatggcaa atacgaaact ctcgcaaggg ctggttattc aggagcagac cgcccacagg 4788 0 gtgactggca gacgtcagca gcgctgacac gccaacaata cgacgactgg cgaaccagat 4794 0 atttgccccg cgtggcaagg ctggctgacc ttggggagaa caacagtctg atgaatgcac 4800 0 agcttgcacg ggtgggaggc cttgccactt ccagtctccg tacagcgcag atggcgcagg 4806 0 ataaccagat ggcgagatac ggggtaaacc gcccggataa tcccgacagt aatacgctgg 4812 0 ggttacgtaa tgccctggca attgctggcg cgaaaaatgg tatccgtgaa gccgaacagg 4818 0 atcgccagat gaatattctg acgggggctt ctgcaccggc aagacagaaa ctgagtgttg 4824 0 gcggccaact ggtggcagcg taagggggca atatgggata cggtttactg gatattgcaa 4830 0 atcagtcgcg gcgtgaggca ttacagggaa taagtgacgc agacagacga cgtgaagaaa 4836 0 ttgaggctgc gaacaaacag atggcggcgc aacagaaagc gcagaacaag cagaatatcg 4842 0 gtacgggcat tggtacgggg gcggctattg gcgcatccgt tggtggtcct gttggtgctg 4848 0 ttgctggagc agtaattggc ggcattgctg gttctttgtt ttaaggagtg gtgaatgagc 4854 0 ggatttgcac aggggttact tgccggattc agcaccgttg accaggcaat gacccgtcgt 4860 0 aaggagcttg gtctgcgtga agcacagctt gcccggcaac agaaaaataa cgagcgcgat 4866 0 tttgagtttg cgcagtctca gtttgaacat aataaaaacg ttgatcagcg gaactttgat 4872 0 tacagagcca aagttgacga ccgtaattat gcactgaagg agagggagtt taacgctaac 4878 0 cagaattacc ggaatgcgtc actgggtatg gagcagcagc gactccagtt gcagaaatac 4884 0 aaccagcgac ggcttgagta taacgatatg attgcccata gccagccact aatggaagcg 4890 0 cttggaaaag caattgaggc tggcgatcag gaggctgcaa cgcgtctgtt cgggcagctg 4896 0 ccaaagggac atccattaat tcttatgtca aacgaaggct atgcagcgaa agcgggtcag 4902 0 gccgtgatca acctgcaaaa aatctttggt gataagccgg acatggcgat cgattcgctg 4908 0 aataccccgg aaaatctcga tgtgctttcc ggcgtgtttg ccccggaact acaacagcgt 4914 0 attggcatgc ctgattcaac cggggacaaa acgataaaag aggccaggat tggcagtatc 4920 0 gtaccagcgc agcaggaagg gtacgtactt attggccttg atctcacata cagcgatggc 4926 0 tccaccgcgc ataaacctgt aacagaatac ggcagtgcgc accctgatga tcaaaccgtg 4932 0 ctggcgatac ccgttgataa ggctatcgct caggtcaggg atcgcagcaa atttgcagag 4938 0 atatcgaaaa attatggtta ttttatgccg aagcagcagg gactttctct gaaagagctt 4944 0 cagaaggggg ccagcaacgt agcggcggac gcgatcaaga atggcggtaa tgctcaggct 4950 0 gcggtggatg aatattatgc tgcgactggt tcacaaccgc atcaacagaa aattcagcaa 4956 0 caaaaacttc agcaacaggt tatcaactgg gcgggagatg atcctgataa gctgtcattt 4962 0 gccagaaatg tagcggcccg tcagcctgaa atgctggaac ctcagaatca gaaattgctg 4968 0 gagaacgggt atgcgaattt tctccgtatt caaaaggcca ggggggaaca ggccagagat 4974 0 gaaagtgctt catctgcatc tcagtttatc cgtggactga aacagaatta cgcccagtaa 4980 0 ttcacgatat tccattaata ccatttcctg atgcccggcc attgtgccgg gtttttttat 4986 0 ggagtctgta tggcctattc agaggaacag cgtcctgagg cgcaactcgg taaccagaat 4992 0 cgtaacagcc tgaacattca gcaacccggc gaaactgaca gctatgaagc atttttctct 4998 0 gatccgaatc gctggaagga taacagtacg tcgttcagcc tgggcgatgt attgccaaca 5004 0 atgggtaaag gtttcgccca gtccgtccgg ggaacagggg aaatggcccg tggactcggt 5010 0 gatgcgatga ttcagagccc ggtaaaaaca ggggcgcgta ttttaaatga gttcagccgt 5016 0 atggggctgc cgggtgtcgc aactgtgcag gatatttttg ccggtggcag caggggggct 5022 0 gatgaggtca tcgataccct gcctgatggc aaaaacgcgg ttactgatac tgtcggtaaa 5028 0 ggtctgaagg caaccggtaa ggctgtcagt gatggtgcca aagccactga tgaatggctg 5034 0 accggtaaga tgtcgccggg tgcagttcgt gcgctgaata cgccgatgac cgaaggctat 5040 0 aatgattctg cggtctgggt ggcgaagggt gtaaacctga ttggtgcgct tgtacctgat 5046 0 atggttgctg gcggtgtggc tagaaaggtg ggtgatgtca cactgcgaaa aatgctgacc 5052 0 gccgggctgg agaaaaaata catcgcggca gggatgcagc cggaaagagc cacggcactg 5058 0 gcagcagaag ctgtcgataa aaaaatgccg gatttattcc aggcgggcct gatcacccat 5064 0 tccactgtaa gtgcacaggg gcagagtgca atggcggcag cagatgctgt tcttaatgct 5070 0 gattactctg agctggcgca gtcaccgaaa tttcagcaga cgtttttgtc cattgacgcc 5076 0 gacccgcagc acgcacagct tactgatcgc cagaaaatgg atctggcaaa agagcgtgtt 5082 0 gccgatgagg tgcgcgcgca gctggcaacc gatcctgaat tgctggctgt gaatgccatg 5088 0 gcggcaaaac tgggtgacgc acaactgttt aatctggtga cacgaggcac agcgaagacc 5094 0 gttaaaagcg gcattgtcag aaatgccacg gaacaggggg cgattaatgc ggcgcagggc 5100 0 ggctattcac gctatcagga aaacacggca ttgcgtgaga ccgccggaat gggtgtgtca 5106 0 ccgtgggagg gcgtggctga cgcaacgatc gaaggtgcag cctttggtgc tgcgatgggg 5112 0 gctccattcg gtgcggttgc cggatatcgt ggcagacgtc aggccgcaga agaaaccgcc 5118 0 atgcgtgatg ctgaaaccgt gcagcaggac gacgcagccc cgcaaccaga atctgttgat 5124 0 ccggtggcgc agcagcgtga atccatgcag ggcatgaatc gcgagcagct tctggagcag 5130 0 tatgctgatg cggatatggc aacagagggt gacgcatccg cagctcatcg ccgggaagct 5136 0 gccagccagt tgttgaatga actggacgaa cagacgaagc gacaggctgt gatgaatgag 5142 0 ctgaaggcga agccgcgttc tgaactgctt gaggaatacc gcagactcag ccagaaagag 5148 0 gggcgcaccg agactgaaga acaacagttt caggcaatac gagaagtcat tcgcccacaa 5154 0 caggaagtga cgccggaagc acagtcacag cctgaaaatg cggaggatgg taacgggagc 5160 0 atttacccga cggtgcggtt ccgggacccg aatgaagtcc gcattgaaat taacgggaat 5166 0 ggtgcgtcca gaccagcgga acgcattgag aaggtgcgcc cggacaaccg ttatttcacg 5172 0 gatgagaaaa gcgccatggg gagtgatgtt ttccgtaatg ccgccgccac cggcctgaaa 5178 0 ccgtccgtag tgaagaaagg cgagaatcag tatgccgttg aaatggataa tcctgcgttc 5184 0 tctgaagatg tggcaacgga aaccattaac accctggctg acggagagcg tattgctgat 5190 0 gctgacccga tggagcagcc cgcgttcatg cgtgacccgc gattccgtgg tttcacgggg 5196 0 gatgatacgg aggtacaggc ccgccttgcc cgtggcaacg cgccgacggc agaggagctt 5202 0 gtacgttcac agatggctga aggtgatgcc ggtccgacag cacaggagtt aactgagcgt 5208 0 ccacgcctgc ccgctcccgg cgatattcat cccggacagg gatatccgtt accgggagaa 5214 0 gtggcgcgta cgccggatga aaatcaggcc ggacgtggtg gtcgttttac cacaaccggt 5220 0 gaggttaagg gccagagttt ccagaaagga caagctccgg caccggaaaa cgccgctggt 5226 0 cgccaggggg aaacactcga gggtgacatg gttcgtcgtg gtctgccgtc accggatgcg 5232 0 cagaacgcga cagcaccggt acgtgaaggg ctaccggctc ctgacattgc gcgtaatgtt 5238 0 cgtatgcctc agcctgaatc acttccccgc actgtacggg actcactgcc tgagcttgca 5244 0 cagcaggcag aagtacgccg acaggccgga ggaaatcgtg acatcccgca gcctgagaca 5250 0 atcgcacctg aatctgaaac aactgtctct actgacaggg aagctaccgt gcgcggaggt 5256 0 gaagtcaggg gcaaaaaaat tgaagacttt ggtgaagaaa ttaagggcgc ggcaaaacac 5262 0 cgttatgcac agcttgctga aacactgggt aaaacgctgg aagacaggga ttatgccacg 5268 0 cagccgctga gcaaactgtt cccgaaaccg gactacgcaa aactggcgaa cgaaggtgct 5274 0 gatgctgata ccctggcaat gatagcgctg tatcgtagcg atattccggc gaagacgaaa 5280 0 cacaatacgg caggctgggg ggagagcata aaaaaagtac gacacagtgt atcggaaatg 5286 0 ctgaacggaa cggtcagcgc gaaacgcctc gcagaatgga tggaaggcag aatgccctcc 5292 0 cgttacgcgg atacctggca actgttacgc actctgccac cctcacagat ggacagggct 5298 0 tctgcttatc gggtggtatc gggtgtgtat caggcggcag gagggaagcg ttacgatccg 5304 0 ccacagaaac tttattcact gcgcaataag gacaataagg ggagtaacct ctttttctcg 5310 0 gaaagcaggg atgaattact ggcaaaggcg aaagtctggt ttgcagagca ggaggaaaaa 5316 0 tcacaggcga aaggtgatga aaaaacagca ccgtcaccgg atgacaaaat ccgctttgac 5322 0 gtttaccgga atacccgcag tggcgatatt tttatcgctt acggtaaaaa caaaatgcgg 5328 0 gtgagaggtg gctttaagtc agccagtgat gcgcgtaagt acattgattc acatcgtgat 5334 0 gagcttgttc gtcatgtgaa ggagatgcgg gagatttcgc gtgaggagca gcgcaacgcc 5340 0 accaaccgcg accgtaccgg accagaacgc cgcaagggga atgtttcacc ggagcagttc 5346 0 agtgatgcgt ttggtttccg tggtgtgcag tttggtaact acgtggaagg tccgcgtcgt 5352 0 caggctgatt tgaaccgggc ttatgactcg ctgcatgacc ttgcggaagt actgaatgta 5358 0 ccgacaaaag cgctttccct gaacggtcgt cttggcctgg catttggtgc ccgtggtaag 5364 0 ggtaaggcgg cggcacacta tgagtcaggt gaggtggcaa tcaacctgac aaaaggtaac 5370 0 ggaccgggtg cgctggcgca cgaatggttc cattctctgg ataattattt tggtcgttat 5376 0 gacgtttcca atgacgggaa aattacgtca ggtggcgact ttatgacgga agcacagcgt 5382 0 gtcaggcgca tatttaaaga cggcaggtat gttgatgctg aatatccggt acgtcaggag 5388 0 gtttacgacg cttttaaagg tgtgattcag gccattaaaa acagtgacat gccgcgtcgt 5394 0 tcagcgcttc tcgatgaggt gcgctcaaaa ccgtactggt caacggatgt tgaaatggcg 5400 0 gcacgtgcct ttgagcgtta tgttcaggat aaggcgcgta tggctggcgt ggagaatgat 5406 0 tatctggtca atatccgtaa ggcacctgag cacaacacag ataacaccta cgcttatccg 5412 0 acgaatgcgg aactggatgg cggtattcgt gaggcattcg atcacctgtt ccgcaccctg 5418 0 aaaacccgtg agacggacaa gggcgttgcg ttttattccc gtaagggcgt tacccgcaca 5424 0 cctgaaggta atctcatttc ggatgttaac cgtagtgcgg aagccaaagg cagcccggtc 5430 0 ccgcaggttg aagcggttgc ccgtggcgtg atgagcggca ttaaggacag tgacctgaag 5436 0 gtccgtgtgg tgaagtcaca gaaagaggct gaagcgctgg cgggtgaatt gttcgatggt 5442 0 tacggcaggg tgcacgcatt ctatcgtccg gataaacgag aaattgtcct ggtggcggat 5448 0 aacatccctg acgggcggac cgttcgcgag aagctgcgtc acgagatcat tcaccatgcc 5454 0 atggagcatg ttgtcacacc agcggaatat cagacgatta tcaaaaccgt gctgaaaacc 5460 0 cgcgacagtg ataacgtcac catccgtgaa gcctggcgta aggttgatgc ttcctatggt 5466 0 aaggaatcac cggaagtaca ggcgggtgaa tttctggcac atatggcgga gaaacagccg 5472 0 aataaattcg tggcggcatg ggagcgtgtt gttgccctgg tcaaaggggt actgcgtcgt 5478 0 acggggttac tgaagccgac ggaactgaac gatatcagac ttgttcgcga gaccatccgt 5484 0 acgttaggcc agcgtgtgcg ggaaggttac acgccgcgtg aggatggcgc gggcgcatcg 5490 0 tttcagtact cccgtagtgg taaacgtgat ccgttcaaag tgccggaagg tgagggcgag 5496 0 cgttatcgtg atgaccttgc cagaatgatg aaatctctgc gcaccacaga tttaacggta 5502 0 aacatcgggc gtacgccgcc ggtattgcgt caccttggtg caccggattt gccgctggtt 5508 0 atttcccgcg atactgtgcg gaaggccacc aatggtgtga aacatgtggt gccgatggat 5514 0 gttatcgaga gactaccgga actgatgcac gatccggatg caatttaccg ctcagcgaca 5520 0 gaaagaaatg cggttgtgat gctgcttgat gccgtggata aaaatggtga tccggtggtg 5526 0 tcagcggtac acatgaaggc tgtccggtcg cgtctggaaa tcaacaaggt agcttctgtt 5532 0 tacggtacag aaaatggaaa aaaactgaag agtatggaaa tgaccgggtt aacgttgtac 5538 0 cggagagaaa aattaagccg cgataacctt ctgcacagag ggctccaatt gcccaaaggg 5544 0 gaacattctt atcgcggctc tgcggataaa atactctatc ctgaagatat tcgcaagggg 5550 0 ccgtattact cccgtaccag cagtctgaca ccggaagaga caattgcatc gcgttttgtg 5556 0 cgccagatgc aggataaatt ccaggtgctg aaagctgttc aggagaatat ccgtaaaact 5562 0 ggcggcaaag tggacgacag taacaacgct tatatggcgg aagaactctt ccacgggaag 5568 0 gcggaaaacg acctgaacgt gatgaaggag cgctacgttc agccactggc taaattactg 5574 0 gcggactaca aaattgcgca ggccgatctg gatgagtacc tctacgcccg tcacgcgccg 5580 0 gaacgtaacg cgcatatcgc gaaaatcaac ccgaaaatgc cggacggcgg ttcggggatg 5586 0 accaacgcgg aagcggcgga aatcatgcag cgtgtacgta acagtggcaa acaggcacag 5592 0 tatgaccgtc tggcagggat tattgacgat atgctggccc gtcgccgtga gcttatccgt 5598 0 gaggccggac ttgaagagaa cggtgtggtg gatgcctggc agaacgccta ccgttactac 5604 0 gttcccctga aaggtcagga tgttgacggt gtggtgtcac tgccccgtac aggtaagggc 5610 0 ttcaccatcg gcggacgtga aagcaggcag gccatggggc gtgcatcccg ggcacagtct 5616 0 ccgtccactc aggcgataca ggacctgagc gaatcgctga tccgccatcg caaaaacgaa 5622 0 gtgggtaacg ccttcctgaa actggtgcag gataatcccg acaaggatta ctggcaggta 5628 0 ttcaccgatg acagaccgga taccatgcgg acgattgcag agcgcaagga ccaggaaact 5634 0 ggtgaaacca ttcgcgaagt tgtcgaacgc cctgtaccga tggcaatgat ggcagaccgg 5640 0 tacttcacca ccaaaaagaa cggcaaaacg tactacatca aactccatga tccgcgcctg 5646 0 atgcgtgcga tgaagagtat gggaccggaa accagcaatg cctttgttcg tacgctgggg 5652 0 aaagttaacc gcttcctggc aacggtgaac acgtcgtata acccggaatt cctggtcagt 5658 0 aacttcatcc gtgacgtgca gacggcggtg atgaacctga aggcggagca gggaaggagc 5664 0 gacggtaaac tgaaagggct ggataactta tccgccctgg ctgtggtgaa agacagccgt 5670 0 tctgccatgt cagccgtata cgccagtctg cgtggtaaaa ccctcacggg aaaaggtgca 5676 0 cagtggcaga aggtgtggaa agagtttgtt gaggacggag ggaaaaccgg ctggtttaac 5682 0 atgggtgacc ttgaaggcca gcagaaggaa atggatcgcc ttgtctcact ggcgaagggg 5688 0 ggatggaaag gccagagtat cggtgcatgg aattcgttcc ttaaccttgt cgaggatgcc 5694 0 aacggtgcgg ttgaaaacgc tctgcgtctt tctgcctata agcacgcccg tgatgccggt 5700 0 ttgtcacgcc agcaggcggc gtctcttgcc aaaaacatga cggtgaactt taaccgtcgt 5706 0 ggtgagcagg gggcgctgat gaattcgctg tacatgttcg ccaacgccag cattcaggga 5712 0 acggcaaatc tggtgagaac gctcggacat cttaatggtg agggaccttt actggagcgc 5718 0 cttcgctgga agaatctgaa tgttccgcag aaaatcgcgc ttgccgctgt gggagcaggt 5724 0 tatctgcttg gctcgcttaa ccgcagcgtg gcgggtgagg atgatgacgg ggttaactgg 5730 0 tatgacaagg tgccgtctca tgtgaaagag cgtaacctcg tcattatgaa atcggtgttc 5736 0 gggggcaagg ccggagagta ctggagtatt cctctgcctt acgggtacaa cgttttcttc 5742 0 ctgctcgggc atactgctga aggtgtggcg gcgggtgacc tgacggcgtc ccgtgctgcc 5748 0 ggtaatgttg ttggtggtgt gcttggtgca ttcagcccga ttggcagtga gacgtcggaa 5754 0 acactgtccg gggcattgct gaaaaatgca gcgccgacca ttctgcgtcc gtttgcgaac 5760 0 cttgccatga atgaaaactt catgggggcg cagatttacc aggagaacat gccgtttggt 5766 0 acaccaaaac ctgacagcca gctgggaaga cgttcaacgc cagaagcgta caaggcgttt 5772 0 gcatcctggc tgaatgcgtt ctcaggtggc agccagtacc gtcccggcgc ggtggatatc 5778 0 acaccggaat cgctgaaatt ctggattgac tatatctccg gagggacagg gcgcttcatt 5784 0 tccaaaacca cggatgcggc ggtgaaatcg ctgaatggta ttgatatacc ggaacagcag 5790 0 gtgcccttcc tggggaaaat ttcgggggag gtgatgccgt atgcagacca gcagaagatg 5796 0 tacgaccgga tgacagagat tgcgcagtat cacgcagagc tgaagagtct gaccggtgca 5802 0 gaaagaacgg cgttcattga cgagaacaac ggaaaattgt cgatgaacgg gcttatgcag 5808 0 gatacccgga agagactgaa ggatttgcgt aaacagcgtg atgccattta cgccgacagt 5814 0 actctcagtc tggcgcaaca gtcggcgatg gtgaaatcgg tagagcggga tatgaaaatt 5820 0 gccgtggatc ggtttaaccg cgagtacaac aaaaaagtgg gagtggatta acagaaatgg 5826 0 ccccgtacgg aagtgcgggg ctgattaaga aataaacact cattgacctg taataaccgg 5832 0 agctattaac atatagtcag aagagcattt catgtgatac agagagccga tttatgttta 5838 0 atgaagaaaa agttgcgcaa atggcagcgt atttgctgaa aaagcatggc ggatctatgc 5844 0 gtttcattaa gctgaagcag caacggtaat ggcgaatagc atttatgagc aaaataatct 5850 0 tgatatgtta ttaggcgatc tgatgtaacc gggatgatgt tcacccctta tcgccgggga 5856 0 acaataccgg caatcagaat tgcggatgga actattcagg cccacgatga tatcgatgag 5862 0 gagttttttc agccagtatt ggatggcttt cttatatcca aatatacgcc atttgacatc 5868 0 ctccacgccc tgaaggacgg ggttttacag cgcaccggat aagattcggt gttttgttga 5874 0 aaaatactgt gataacaaac agaaaacccg tcagtaagac gggcttagca agctgggacg 5880 0 gttactttaa taatttcagt gcctttacat ccacttcaac actgctcagg tctttatcaa 5886 0 tttcaccctc aattcttact ttgtctttcg gagaaacatt ctgcccggcc catatgctgt 5892 0 catcgatatc cgtgacaatt gtcccgctat tgtcacgaaa ctcataacgt tcatcaccca 5898 0 cttttttaac gatgctccct tcaaggataa cccatgcatc atccttcagt tcttttgcct 5904 0 gcgctactgt tgaacgctct gcttcaggcc cttggaaacc gccctgctgt gcaaaagcgc 5910 0 caaaagacac accagaaata agtgctgcaa tcaatacctt tttcattcat agtcctcttt 5916 0 cagagatgaa cattcaaaca gcattttcag tatggtaaag cgcgggtgcg ttgaggatgc 5922 0 ctgacacatc agaggtggcg ggagattact cccccgcttg gtctcttact tctcagattc 5928 0 gtagtctacg aagacagcga cctccgtctg accggttcgg attcgcacct cgcagaggtc 5934 0 tttcctcgtt accagtgccg tcactatgac ggttaaacag atgacgatca gggcgattaa 5940 0 catcgccttt tgctgcttca tagcctgctt ctccttgcct ttcggcacgt aagaggctaa 5946 0 cctacatgtg ttcagcatgg attgagcctc agattaatgt taagcgtctt gccggacgcg 5952 0 taatgttaac tggggctttt ctctatctgc cgttggtgtt catgcccgag gcagatagcc 5958 0 tcaagcaccc gcagcaattc tacttaactc tccttttccc gcaaaccgtt tttatctcca 5964 0 gcgacaaatc gaatacacaa ccagcaccac cgccattact gttcctacat ttgcgaatgc 5970 0 ttcaggccag gtcattgatt caccttctgc tcaatatttt taaggtcatt ttccgcatac 5976 0 agtattgcag ttcttgctgc ccgcaaccgt gctttggtgt tcttttcttc acgctcgagg 5982 0 ctggcaacag attctcggag ctgatcgtgt ctgttatgaa gctgtctaat ctctctcacc 5988 0 acagcctcac catcgttcgc acaccgcaga acatactgaa aagggtccac aacacatccg 5994 0 cactgcaagc acaggataac gtgatcctgt tcatgaacct caatggcccg atgcttacag 6000 0 ctctgttgtg tgtagttttt tctgccagtt actgtaatgt tcagcagctt ctcttcatcg 6006 0 cgctttggct gcaccagtgt gatgatatta tcgccttcat tttccatcag ttcacctcct 6012 0 gcggcggttc tggtagcggc atccagtgtg acggtttcca cgacgcacca ggaattatcc 6018 0 acccatcatt agcgtcagga tgccccggga tgtaagtcgc ccacttcatt cgccagtcac 6024 0 ctttcctgtc aaactccacg gcaacaagaa cggctgtttt ggtatccggc attcgctcac 6030 0 tacaacttat ccaaccatcc ggagttaccg gagagttgcc agacagcgca ttctgcaacc 6036 0 gttccagctt aacgtattcc tgaaccctgt ttccgtcgca cgcctgaagc cattgctcag 6042 0 ccttttgcgc atcagtgtga aaggcacaag tgcgaccgtc atcaaattgc atttcgtaga 6048 0 ggttagcaat ctgttcaaac tgcgtgtgtg gcaacttgta agtttggctt acgagttcgg 6054 0 cttccagttc tgctatgcgc ttctctgatg cttcaagtaa cgcctgctta tcgcgtagcg 6060 0 cttcttccag ttcagcaaca tggcattcac tatcaataag gttgttctct gctgctccca 6066 0 gctcaactct cagcttccca accgtaagcg caatctcctc gttctcctgg tcgcggcgtt 6072 0 tgatgtattg ctggtttctt tcccgttcat ccagcagttc cagcacggta gccgggttag 6078 0 cctctgctat gaattcagcg ttgcataagc ctgagcatct gtttcaacca ggcagttaac 6084 0 atgacattct gcaatcacgc caccgggttc tcctttccat ttttggcaaa caaaaactcc 6090 0 tgttaaattg ccgtgctggt taacagatgt atgccctacg atgtagcttc ctttagttgc 6096 0 tttctctgcc ttttcacgca gtgcctgata gtcaatcttg ctcatttttc tcttcactcc 6102 0 ggtatacaag gattactacg ccccctctgc taattgcgcg agctggatcc cctggttcca 6108 0 tgccgtcaat accgaaggct tcgaaaaatg catctattgc cttttggcgt tgctcctgct 6114 0 tacggcgttt attccatttt ttcatgaaca acagtgacag ccatcgtccg ctgcagaaca 6120 0 tgatgtagaa ataaccaagg agcgctaggc cggtgttcag ggctgtatcg atcgttatcg 6126 0 tggtgttgat gttcacttca cacctctctg tttgttgata agttcaatat cctgctggca 6132 0 actggcgcaa gctctgcatc cacgaacagc caggcgtcgc cgctcatcta tcggatcgcc 6138 0 acactcgcaa caatgagtag cagatggggc attactatcg gatttgtatt tttgcaggga 6144 0 gagattgcgc tgcaattctt cgatttcagc ggcgttgtcg atgatatctg ccattttcct 6150 0 ttccttcagg catgaaaaaa ggagccgaag ctcctttggt tttagaattc gaattgcctt 6156 0 gcccgcaggc ttttcagcat tggtctggcc cgctgaacta cgaaactcga ctggtcaagc 6162 0 cgtgccgcct ctctcagtag cacatctctg ttcttcgtca ccatgtagat ggtctcaaac 6168 0 gcaatgtcat acagcttgtt cgtgtatgag gagttcagct ctttcatgat cggatacagg 6174 0 tgtttgctga ggtcctgggc tttttccatc cagagttgca tgtagcagag gaggatgatt 6180 0 tcctcgtctg tgaattgttg ctgtggttct gcttgtgccg actgcatgtt gcgaagtttc 6186 0 ttttcgcact cgatgaagta tctgcgtatc tgtcggcctt tttcgttacg ctctaccatc 6192 0 gccgtttctt tggctgtatc gagggtaagg tggtagtctt ttttccctcg cccataacct 6198 0 atttcccgtt tctgggaaat agctatatag tcctgatttt caacgaatcc gtactcttca 6204 0 atacgttctg taatccacga tgcaaagcgt ttacctactc caagaaaagt atgtaaatca 6210 0 cgggcattaa cgagaagagt ggtttcgttg gcgatagtgc cgttgaatac ggggatgagt 6216 0 tgactggtca tgatgacctc cttatttgtt tagtttataa ccgccagtta gtagctggcg 6222 0 gtcgggtgtc aactgagcca aataagaagc tctgggcata ttccccttgc gggtgttgta 6228 0 ttacgcctct ccacccgacc tttgtacgga tgtaactatg ccaaattgca ggcataaaaa 6234 0 agccgcaaag ctatcgggtg cggagaccgc ttatttgttc agtgcggtca gtatgcgata 6240 0 gctctggagg atttgtcaat cagcggaata ttgatgaacg ggtaacggta aatgcctcat 6246 0 ccagaaaatt aacgcaaatt cgcatcgcaa acttgcgtta attatctgaa atatcaagtt 6252 0 aaatcccctt aaatgtttgg ggcactattg gggcaaaatg tggttgtttg gggcatattt 6258 0 ggggcaaaaa agaacgtata aagaacggtg taaaattgat ttcttcatgg tcaaaatgag 6264 0 gtgtaacaga ttgaaaaata tatgctcttg gacgatcttc ggtaattctg tgtttttaat 6270 0 gcttcatg 6270 8 <210> 245 <211> 437 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29..1339) <400> 245 Met Ala Asn Ser Ala Tyr Pro Ala Gly Val Glu Asn His Gly Gly Lys 1 5 10 15 Leu Arg Ile Thr Phe Lys Tyr Arg Gly Lys Arg Val Arg Glu Asn Leu 20 25 30 Arg Val Pro Asp Thr Pro Lys Asn Arg Lys Ile Ala Gly Glu Leu Arg 35 40 45 Ala Ser Val Cys Phe Ala Ile Arg Thr Gly Thr Phe Asp Tyr Ala Asp 50 55 60 Arg Phe Pro Asp Ser Pro Asn Leu Lys Leu Phe Gly Leu Val Lys Lys 65 70 75 80 Asp Ile Thr Val Gly Glu Leu Ala Gln Lys Trp Leu Thr Leu Lys Ala 85 90 95 Met Glu Ile Gly Ser Asn Ala Leu Asn Arg Tyr Gln Ser Val Met Lys 100 105 110 Asn Met Leu Pro Arg Leu Gly Pro Gly Arg Leu Ala Ser Ser Ile Thr 115 120 125 Lys Glu Asp Leu Leu Phe Ile Arg Lys Asp Leu Leu Thr Gly Glu Lys 130 135 140 Gly Ser Arg Lys Thr Ser Thr Ser Arg Lys Gly Arg Thr Val Pro Thr 145 150 155 160 Val Asn Tyr Tyr Met Thr Thr Thr Ala Gly Met Phe Ser Phe Ala Ala 165 170 175 Glu Asn Gly Tyr Leu Glu Lys Asn Pro Phe Asn Ser Ile Thr Pro Leu 180 185 190 Arg Lys Ser Lys Pro Val Pro Asp Pro Leu Thr Arg Asp Glu Phe Ser 195 200 205 Arg Leu Ile Asp Ala Cys His His Gln Gln Thr Lys Asn Leu Trp Thr 210 215 220 Val Ala Val Phe Thr Gly Met Arg His Gly Glu Ile Ala Ala Leu Ala 225 230 235 240 Trp Glu Asp Ile Asp Leu Lys Ala Gly Thr Ile Thr Val Arg Arg Asn 245 250 255 Phe Thr Lys Ile Gly Asp Phe Thr Leu Pro Lys Thr Asp Ala Gly Thr 260 265 270 Asn Arg Val Ile His Leu Leu Ala Pro Ala Ile Glu Ala Leu Lys Asn 275 280 285 Gln Ala Met Leu Thr Arg Leu Ser Arg Gln His Gln Ile Thr Val Gln 290 295 300 Leu Arg Glu Tyr Gly Arg Thr Ile Leu His Glu Cys Thr Phe Val Phe 305 310 315 320 Cys Pro Gln Ile Val Arg Lys Asn His Lys Ala Gly Ile Asn Tyr Ala 325 330 335 Val Ser Ser Ile Gly Ala Thr Trp Asp Ser Ala Ile Lys Arg Ala Gly 340 345 350 Ile Arg Ser Arg Lys Ala Tyr Gln Ser Arg His Thr Tyr Ala Cys Trp 355 360 365 Ala Leu Ser Ser Gly Ala Asn Pro Thr Phe Ile Ala Ser Gln Met Gly 370 375 380 His Ser Ser Ala Ser Met Val Tyr Asn Val Tyr Gly Ala Trp Met Pro 385 390 395 400 Glu Cys Ser Val Thr Gln Val Ala Met Leu Asn Asn Val Leu Asn Ala 405 410 415 Arg Ala Pro Asp Val Pro Gln Ser Asp Gln Glu Asp Glu Ile Lys Leu 420 425 430 Tyr Phe Ser Lys * 435 <210> 246 <211> 95 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1392..1676) <400> 246 Met Arg Glu Leu Val Asn Gln His Asn His Gly Ile Gln Pro Val Ile 1 5 10 15 Thr Pro Val Val Gln Ile Asn Ala Asn Glu Trp Val Thr Leu Glu Leu 20 25 30 Leu Met Ala Val Thr Gly Leu Arg Lys Gly Thr Ile Leu Arg Ala Arg 35 40 45 Asp Ser Ala Trp Met Asn Gly Arg Glu Tyr Lys Gln Ile Ala Pro Asp 50 55 60 Gly Thr Pro Lys Lys Asn Ser Glu Cys Leu Tyr His Leu Pro Thr Ile 65 70 75 80 Asn Thr Trp Ile Lys Asn Gln Pro Leu Pro Ser Gln Asp Val * 85 90 <210> 247 <211> 104 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1762..2073) <400> 247 Met Glu Met Ile Met Ala Cys Ser Thr Phe Asn Pro Leu Thr Leu Gln 1 5 10 15 Lys Tyr Gln Pro Asp Pro Glu Asp Leu Cys Ser Leu Cys Gly Gly Asn 20 25 30 His Gly Lys Ala Ala Met Ile Glu Cys Lys Asp Lys Ile His Ile Cys 35 40 45 Leu Asn Cys Val Asp Val Leu Val Asp Ile Lys Asn Glu Arg Glu Asp 50 55 60 Lys Lys Arg Ser Glu Ala Val Arg Ala Leu Asp Ser Trp Met Arg Asp 65 70 75 80 Gly Tyr Ser Ala Ala Gln Ile Tyr Asp Leu Ala Ile Ser Lys Gly Glu 85 90 95 Ile Pro Gly Val Arg Ile Glu * 100 <210> 248 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2133..2477) <400> 248 Met Val Leu Ser Lys Gln Leu Thr Gly Cys Arg Tyr Gln Asn Arg Arg 1 5 10 15 Arg Arg Leu Thr Val Ala Asn Leu Gln Leu Ala Val Lys Gly Glu Tyr 20 25 30 Phe Asp Ala Met Ile Arg Gly Glu Lys Thr Glu Glu Tyr Arg Leu Phe 35 40 45 Asn Asp Tyr Trp Asn Lys Arg Ile Met Phe Arg Glu Tyr Asp Arg Leu 50 55 60 Ile Ile Thr Lys Gly Tyr Pro Lys Arg Asp Asp Ser Ser Arg Arg Ile 65 70 75 80 Asp Val Pro Tyr Asp Gly Tyr Glu Ile Lys Thr Ile Thr His Pro His 85 90 95 Phe Gly Asp Lys Pro Val Lys Val Phe Ala Ile Lys Val Asn Ile Gly 100 105 110 Asn Glu * <210> 249 <211> 208 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2410..3033) <400> 249 Met Thr Thr Phe Thr Asp Lys Glu Met Ile Lys Glu Ile Lys Glu Arg 1 5 10 15 Ile Gly Ser Leu Asp Val Arg Asp Asn Ile Glu Arg Arg Ala Tyr Glu 20 25 30 Ile Ala Leu Thr Ala Leu Thr Thr Glu Pro Phe Ala Thr Ile Asp Thr 35 40 45 Val Gly Ile Glu Leu Val Lys Tyr Gly Cys Asn Thr Phe Ile Cys Pro 50 55 60 Asp Asn Ser Met Glu Pro Gly Asn Val Pro Leu Tyr Ile Gly Leu Pro 65 70 75 80 Arg Ile Asp Pro Ala Ser Gln Thr Ala Lys Leu Ser Phe Gln Glu Trp 85 90 95 Leu Ser Glu Gln Lys Glu Lys Ile Asp Val Asp Cys Gly Cys Val Ser 100 105 110 Ile Glu Thr Leu Thr His Trp Met Lys Ser Ala Tyr Glu Ala Gly Asn 115 120 125 Ser Pro Val Thr Pro Asp Ser Trp Ile Ser Cys Ser Asp Arg Met Pro 130 135 140 Glu Lys Gly Gln Asn Val Leu Ile Ser Val Asn Phe Asp Ser Ser Leu 145 150 155 160 Val Glu Pro Leu Ile Cys Ser Ala Arg Tyr Thr Gly Ser Thr Phe Arg 165 170 175 Arg Gly Asp Ala Thr Ile Lys Pro Gly Asn Gly Ile Glu Gln Ala Thr 180 185 190 His Trp Met Pro Leu Pro Glu Pro Pro Gln Glu Val Asn Arg Gly * 195 200 205 <210> 250 <211> 96 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3037..3324) <400> 250 Met Ala Thr Leu Gln Glu Leu Ile Asp Leu Thr Pro Glu Gln Glu Lys 1 5 10 15 Ala Trp Asn Arg Leu Val Lys Ala Val Lys Asp Phe Arg Ala Ala Gly 20 25 30 Gly Lys Phe Tyr Ser Val Leu Asp Thr Leu Ser Ala Tyr Asn Gly Glu 35 40 45 His Val Ala Ser Ile Asp Asn Asp Lys Gly Tyr His Thr Ala Ser Val 50 55 60 Tyr Met Pro Ser Ile Asp Ala Pro Gly Leu Thr Ser Trp Ala Asp Asp 65 70 75 80 Trp His Gly Ile Thr Leu Lys Asp Gly Val Glu Val Asp Lys Asp * 85 90 95 <210> 251 <211> 73 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3326..3544) <400> 251 Val Pro Thr Leu Phe Arg Lys Glu Tyr Pro Arg Lys Ser Arg Ala Thr 1 5 10 15 Glu Phe Leu Phe Leu Ile Leu Phe Ile Val Leu Met Thr Pro Ile Ser 20 25 30 Pro Leu Ile Phe Val Trp Ala Ile Gly Lys Ile Ile Glu Leu Val Ile 35 40 45 Glu Leu Tyr Asn Asp Val Val Trp Ala Ser Phe Asn Thr Leu His Asn 50 55 60 Lys Ile Asn Pro Tyr Lys Glu Asn * 65 70 <210> 252 <211> 96 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3546..3833) <400> 252 Val Val Phe Ala Lys Ser Pro Ala Arg Ser Lys Thr Ala Gly Lys Thr 1 5 10 15 Thr Cys Ala Leu Lys Glu Ser Asp Met Ala Ile Ala Ala Ser Tyr Thr 20 25 30 Met His Leu Tyr Cys Asp Cys Leu Gln Cys Thr Asp Gly Lys Tyr Lys 35 40 45 Ser Pro Asp Phe Gly Glu Tyr Ile Gly Thr Ser Trp Ala Gly Cys Ala 50 55 60 Lys Glu Ala Arg Lys Asp Gly Trp Arg Ile Ser Lys Asp Lys Thr Arg 65 70 75 80 Ala Phe Ala Pro Gly His Lys Ile Leu Arg Ser Asn Lys Gly Glu * 85 90 95 <210> 253 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3763..4230) <400> 253 Met Leu Arg Pro Thr Leu Ile Ala Asn Met His Arg Leu Thr Lys Ser 1 5 10 15 Leu Trp Arg Phe Thr Ser Gly Phe Gly Asn Lys Val Lys Pro Ser Ala 20 25 30 Pro Leu Ala Phe Ala Ser Lys Glu Val Ser Asn Ala Cys Gly Met Tyr 35 40 45 Arg Leu Val Thr Val Ser Asp Ser Phe Leu Gly Phe Cys Ala Asn Cys 50 55 60 Lys Glu His His Pro Asp Thr Lys Ala Pro Pro Tyr Arg Tyr Cys Ser 65 70 75 80 Gly Thr Thr Ser Ser Lys Glu Met Gln Glu Ser Lys Thr Met Lys Asn 85 90 95 Arg Lys Ala Lys Ile Leu Leu Val Arg Arg Asn Ala Pro Gly Val Trp 100 105 110 Gln Trp Val Arg Leu Ser Asn Arg Arg Met Gly Leu Met Lys Tyr Tyr 115 120 125 Gly Met Met Asp Cys Gly Phe Cys Lys Lys Pro Ser Ala Glu Gln Asn 130 135 140 Arg Trp Lys Asn His Leu Arg Thr Lys Gly Glu * 145 150 155 <210> 254 <211> 258 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4103..4876) <400> 254 Val Ser Glu Ile Asn Tyr Gln Ala Leu Arg Glu Lys Ala Glu Lys Ala 1 5 10 15 Thr Lys Gly Ser Tyr Ile Val Gly His Thr Ser Val Asn Gln His Gly 20 25 30 Asn Leu Thr Gly Val Phe Val Cys Gln Lys Trp Lys Gly Glu Pro Gly 35 40 45 Gly Val Ile Ala Glu Cys His Val Asn Cys Leu Ile Glu Ser Asp Asp 50 55 60 Gln Ala Tyr Ala Asn Ala Glu Phe Ile Ala Glu Ala Asn Pro Ala Thr 65 70 75 80 Val Leu Ala Leu Leu Asp Glu Gln Glu Arg Asn Gln Gln Tyr Ile Lys 85 90 95 Arg Arg Asp Gln Glu Asn Glu Glu Ile Ala Leu Thr Val Gly Lys Leu 100 105 110 Arg Val Glu Leu Glu Ala Ala Glu Asn Asn Leu Ile Asp Ser Glu Cys 115 120 125 His Val Ala Glu Leu Glu Glu Ala Leu Arg Asp Lys Gln Ala Leu Leu 130 135 140 Glu Ala Ser Glu Lys Arg Asn Ala Lys Leu Gln Ser Glu Asn Ala Tyr 145 150 155 160 Ile Arg Asn Arg Tyr Lys Glu Leu Asp Leu Leu Ile Gly Lys Asn Ile 165 170 175 Leu Val Met Gln Ala Ala Ile Ile Glu Trp Gln Ala Thr Gly Asp Ala 180 185 190 Lys Ser Gly Leu Ala Trp Ile Tyr Asn Thr Leu Phe Gly Pro Gly Glu 195 200 205 Leu Pro Asp Glu Ser Glu Lys Asp Ala Gln Ala Tyr Phe Asn Arg Lys 210 215 220 Tyr Ala Pro Ile Asp Glu Lys Leu Met Ala Leu His Lys Trp Phe Trp 225 230 235 240 Glu Gln Ser Glu Ala Glu Arg Ala Ala Gly Ile Arg Ile Lys Arg Gly 245 250 255 Glu * <210> 255 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4873..5094) <400> 255 Met Ala Asp Leu Ile Asp Ser Ala Ser Glu Ile Glu Glu Leu Gln Arg 1 5 10 15 Asn Thr Ala Ile Lys Met Arg Arg Leu Asn His Gln Ala Ile Ser Ala 20 25 30 Thr His Cys Cys Glu Cys Gly Asp Pro Ile Asp Glu Arg Arg Arg Leu 35 40 45 Ala Val Gln Gly Cys Arg Thr Cys Ala Ser Cys Gln Glu Asp Leu Glu 50 55 60 Leu Ile Ser Lys Gln Arg Gly Ser Lys * 65 70 <210> 256 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5193..5408) <400> 256 Met Thr Pro Gln Gln Glu Asn Ala Leu Arg Ser Ile Ala Arg Gln Ala 1 5 10 15 Asn Ser Glu Ile Lys Lys Ala Arg Gln Gln Phe Pro Asp Lys Asn Val 20 25 30 Asp Asp Ile Cys Arg Ser Val Leu Lys Lys His Arg Glu Thr Val Thr 35 40 45 Leu Met Gly Phe Thr Pro Thr His Leu Ser Leu Ala Ile Gly Met Leu 50 55 60 Asn Gly Val Phe Lys Glu Arg * 65 70 <210> 257 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5485..5676) <400> 257 Met His Lys Ala Ser Pro Val Glu Leu Arg Thr Ser Ile Glu Met Ala 1 5 10 15 His Ser Leu Ala Gln Ile Gly Val Arg Phe Val Pro Ile Pro Val Glu 20 25 30 Thr Asp Glu Glu Phe His Thr Leu Ala Thr Ser Leu Ser Gln Lys Leu 35 40 45 Glu Met Met Ala Ala Lys Ala Glu Ala Asn Glu Arg Asp Pro Ala * 50 55 60 <210> 258 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5649..5831) <400> 258 Met Lys His Pro His Asp Asn Ile Arg Val Gly Ala Ile Thr Phe Val 1 5 10 15 Tyr Ser Val Thr Lys Arg Gly Trp Val Phe Pro Gly Leu Ser Val Ile 20 25 30 Arg Asn Pro Leu Lys Ala Gln Arg Leu Ala Glu Glu Ile Asn Asn Lys 35 40 45 Arg Gly Ala Val Cys Thr Lys His Leu Pro Leu Ser * 50 55 60 <210> 259 <211> 227 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5828..6508) <400> 259 Met Thr Pro Asp Ile Ile Leu Gln Arg Thr Gly Ile Asp Val Arg Ala 1 5 10 15 Val Glu Gln Gly Asp Asp Ala Trp His Lys Leu Arg Leu Gly Val Ile 20 25 30 Thr Ala Ser Glu Val His Asn Val Ile Ala Lys Pro Arg Ser Gly Lys 35 40 45 Lys Trp Pro Asp Met Lys Met Ser Tyr Phe His Thr Leu Leu Ala Glu 50 55 60 Val Cys Thr Gly Val Ala Pro Glu Val Asn Ala Lys Ala Leu Ala Trp 65 70 75 80 Gly Lys Gln Tyr Glu Asn Asp Ala Arg Thr Leu Phe Glu Phe Thr Ser 85 90 95 Gly Val Asn Val Ile Glu Ser Pro Ile Ile Tyr Arg Asp Glu Ser Met 100 105 110 Arg Thr Ala Cys Ser Pro Asp Gly Leu Cys Ser Asp Gly Asn Gly Leu 115 120 125 Glu Leu Lys Cys Pro Phe Thr Ser Arg Asp Phe Met Lys Phe Arg Leu 130 135 140 Gly Gly Phe Glu Ala Ile Lys Ser Ala Tyr Met Ala Gln Val Gln Tyr 145 150 155 160 Ser Met Trp Val Thr Arg Lys Asp Ala Trp Tyr Phe Ala Asn Tyr Asp 165 170 175 Pro Arg Met Lys Arg Glu Gly Leu His Tyr Val Val Val Glu Arg Asp 180 185 190 Glu Lys Tyr Met Ala Ser Phe Asp Glu Met Val Pro Glu Phe Ile Glu 195 200 205 Lys Met Asp Glu Ala Leu Ala Glu Ile Gly Phe Val Phe Gly Glu Gln 210 215 220 Trp Arg * 225 <210> 260 <211> 262 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6505..7290) <400> 260 Met Ser Thr Ala Leu Ala Thr Leu Ala Gly Lys Leu Ala Glu Arg Val 1 5 10 15 Gly Met Asp Ser Val Asp Pro Gln Glu Leu Ile Thr Thr Leu Arg Gln 20 25 30 Thr Ala Phe Lys Gly Asp Ala Ser Asp Ala Gln Phe Ile Ala Leu Leu 35 40 45 Ile Val Ala Asn Gln Tyr Gly Leu Asn Pro Trp Thr Lys Glu Ile Tyr 50 55 60 Ala Phe Pro Asp Lys Gln Asn Gly Ile Val Pro Val Val Gly Val Asp 65 70 75 80 Gly Trp Ser Arg Ile Ile Asn Glu Asn Gln Gln Phe Asp Gly Met Asp 85 90 95 Phe Glu Gln Asp Asn Glu Ser Cys Thr Cys Arg Ile Tyr Arg Lys Asp 100 105 110 Arg Asn His Pro Ile Cys Val Thr Glu Trp Met Asp Glu Cys Arg Arg 115 120 125 Glu Pro Phe Lys Thr Arg Glu Gly Arg Glu Ile Thr Gly Pro Trp Gln 130 135 140 Ser His Pro Lys Arg Met Leu Arg His Lys Ala Met Ile Gln Cys Ala 145 150 155 160 Arg Leu Ala Phe Gly Phe Ala Gly Ile Tyr Asp Lys Asp Glu Ala Glu 165 170 175 Arg Ile Val Glu Asn Thr Ala Tyr Thr Ala Glu Arg Gln Pro Glu Arg 180 185 190 Asp Ile Thr Pro Val Asn Asp Glu Thr Met Gln Glu Ile Asn Thr Leu 195 200 205 Leu Ile Ala Leu Asp Lys Thr Trp Asp Asp Asp Leu Leu Pro Leu Cys 210 215 220 Ser Gln Ile Phe Arg Arg Asp Ile Arg Ala Ser Ser Glu Leu Thr Gln 225 230 235 240 Ala Glu Ala Val Lys Val Leu Gly Phe Leu Lys Gln Lys Ala Ser Glu 245 250 255 Gln Lys Val Ala Ala * 260 <210> 261 <211> 139 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7296..7712) <400> 261 Met Asp Ile Asn Thr Glu Thr Glu Ile Lys Gln Lys His Ser Leu Thr 1 5 10 15 Pro Phe Pro Val Phe Leu Ile Ser Pro Ala Phe Arg Gly Arg Tyr Phe 20 25 30 His Ser Tyr Phe Arg Ser Ser Ala Met Asn Ala Tyr Tyr Ile Gln Asp 35 40 45 Arg Leu Glu Ala Gln Ser Trp Thr Arg His Tyr Gln Gln Ile Ala Arg 50 55 60 Glu Glu Lys Glu Ala Glu Leu Ala Asp Asp Met Gly Lys Gly Leu Pro 65 70 75 80 Gln His Leu Phe Glu Ser Leu Cys Ile Asp His Leu Gln Arg His Gly 85 90 95 Ala Ser Lys Lys Ala Ile Thr Arg Ala Phe Asp Asp Asp Val Glu Phe 100 105 110 Gln Glu Arg Met Ala Glu His Ile Arg Tyr Met Val Glu Thr Ile Ala 115 120 125 His His Gln Val Asp Ile Asp Ser Glu Val * 130 135 <210> 262 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7667..7936) <400> 262 Met Pro Leu Gln Gly Gly Leu Leu Leu Ala Ala Leu Pro Asn Leu Tyr 1 5 10 15 Leu Asn Glu Ser Pro Val Asn Tyr Val Thr Asp Gly Asn Ala Leu Ser 20 25 30 Thr Tyr Leu Ile Ser Gln Glu Ser Gln Lys Met Asp Gln Thr Leu Met 35 40 45 Ala Ile Gln Thr Lys Phe Thr Ile Ala Thr Phe Ile Gly Asp Glu Lys 50 55 60 Met Phe Arg Glu Ala Val Asp Ala Tyr Lys Lys Trp Ile Leu Ile Leu 65 70 75 80 Lys Leu Arg Ser Ser Lys Ser Ile His * 85 <210> 263 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7779..7943) <400> 263 Met Gln Tyr Ala Ile Ala Gly Trp Pro Val Ala Gly Cys Pro Ser Glu 1 5 10 15 Ser Leu Leu Glu Arg Ile Thr Arg Lys Leu Arg Asp Gly Trp Lys Arg 20 25 30 Leu Ile Asp Ile Leu Asn Gln Pro Gly Val Pro Lys Asn Gly Ser Asn 35 40 45 Thr Tyr Gly Tyr Pro Asp * 50 <210> 264 <211> 123 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8016..8384) <400> 264 Met Ser Asn Ile Lys Lys Tyr Ile Ile Asp Tyr Asp Trp Lys Ala Ser 1 5 10 15 Ile Glu Ile Glu Ile Asp His Asp Val Met Thr Glu Glu Lys Leu His 20 25 30 Gln Ile Asn Asn Phe Trp Ser Asp Ser Glu Tyr Arg Leu Asn Lys His 35 40 45 Gly Ser Leu Leu Asn Ala Val Leu Ile Met Leu Ala Gln His Ala Leu 50 55 60 Leu Ile Ala Ile Ser Ser Asp Leu Asn Ala Tyr Gly Val Val Cys Glu 65 70 75 80 Phe Asp Trp Asn Asp Gly Asn Gly Gln Glu Gly Trp Pro Pro Met Asp 85 90 95 Gly Ser Glu Gly Ile Arg Ile Thr Asp Ile Asp Thr Ser Gly Ile Phe 100 105 110 Asp Ser Asp Asp Met Thr Ile Lys Ala Ala * 115 120 <210> 265 <211> 84 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8567..8818) <400> 265 Met Glu Phe His Glu Ser Ala Ile Cys Asp Phe Arg Ala Asn Ala Asn 1 5 10 15 Ser Val Lys Pro Gln Pro Ile Ala Val Leu Phe Lys Thr Met Gly Ala 20 25 30 Trp Ala Val Leu Cys Phe Ala Ala Asp Asp Thr Asp Ala Arg Met Ala 35 40 45 Ile Gly Gln Glu Met Glu Met Asp Pro Thr Asn Asp Glu Phe Ile Ile 50 55 60 Tyr Gly Ala Pro Ser Asn Tyr Leu Leu Asp Thr Cys Asn Ile Tyr Asn 65 70 75 80 Lys Ala Ala * <210> 266 <211> 91 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8877..9149) <400> 266 Met Ser Arg Lys Thr Glu Phe Lys Gly Thr Ala Ala Ser Arg Arg Arg 1 5 10 15 Ala Arg Arg Ala Asn Leu Gln Ser Gln Glu Ala Ile Ser Ser Asp Lys 20 25 30 Leu His Arg Pro Thr Pro Ser Arg Val Val Leu Gln Cys Lys Arg Lys 35 40 45 Pro Ala Met Arg Ala Glu Val Ile Thr Leu Thr Thr Leu Thr Arg Lys 50 55 60 Tyr Glu Gly Ser Thr Cys Leu Pro Asn Val Ala Leu Tyr Ala Ala Gly 65 70 75 80 Tyr Arg Lys Ser Lys Gln Leu Thr Ala Arg * 85 90 <210> 267 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9127..9309) <400> 267 Met Glu Gln Thr Gly Arg Leu Phe Lys Gln Arg Arg Leu Ser Thr Thr 1 5 10 15 Trp Leu Lys Ser Gln Ile Thr Gln Pro His Lys Leu Trp Asp Ala Met 20 25 30 Pro Lys Gln Pro Ser Gln Glu Glu Leu Arg Asp Cys Ile Ala Lys Val 35 40 45 Tyr Ser Gly Gly Ile Tyr Val Gln Lys Asn Arg Ile * 50 55 60 <210> 268 <211> 54 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9606..9767) <400> 268 Met Leu Thr His Met Phe Lys Ile Ser Met Pro Tyr Pro Phe Ile Gly 1 5 10 15 Ile His Met Asn Phe Ser Ile Glu Leu Val Ile Gln Ile Val Cys Arg 20 25 30 His Leu Cys Phe Leu Ile Leu Ala Ala Ala Leu Gln Pro Leu Glu Lys 35 40 45 Met Tyr Gln Thr Arg * 50 <210> 269 <211> 174 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9878..10399) <400> 269 Met Ala Lys Ser Asn Val Ser Val Gln Ala Phe Lys Asp Phe Leu Glu 1 5 10 15 Glu Leu Met Ser Leu Asn Ile Met Lys Glu Ala Thr Ala Arg Asn Leu 20 25 30 Lys Asn Ser Ser Ala Arg Leu Leu Thr Val Val Gln Glu Glu Glu Met 35 40 45 Gly Asp Val Thr Gln Leu Asp Val Asn Glu Leu Ala Glu Arg Tyr Ile 50 55 60 Asn Ala Thr Glu Pro Lys Pro Ser Asp Ser Ser Ile Thr Ala Tyr Lys 65 70 75 80 Ser Arg Met Glu Ser Ala Ile Lys Lys Phe Val Ala Phe Gln Ser Gly 85 90 95 Glu Glu Ile Pro Tyr Thr Pro Ile Asp Lys Glu Ser Ser Glu Glu Lys 100 105 110 Asp Leu Thr Gly Glu Pro Thr Lys Val Glu Gly Lys Ala Asn Ala Leu 115 120 125 His Thr Tyr Asp Leu Pro Val Val Leu Arg Pro Glu Ser Gly Val Thr 130 135 140 Val Thr Ile Lys Gly Ile Pro Asn Asp Ile Thr Asn Glu Glu Ala Glu 145 150 155 160 Arg Ile Ser Ser Ile Leu Lys Val Tyr Val Arg Pro Gln * 165 170 <210> 270 <211> 218 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10901..11554) <400> 270 Met Lys Trp Tyr Glu Leu Ala Arg Ser Arg Met Lys Glu Leu Gly Ile 1 5 10 15 Thr Gln Glu Lys Leu Ala Glu Glu Leu Gly Met Thr Gln Gly Gly Ile 20 25 30 Gly His Trp Leu Arg Gly Ser Arg His Pro Ser Leu Ser Asp Ile Gly 35 40 45 Val Val Phe Lys Tyr Leu Gly Ile Asp Asn Ile Ser Phe Asn His Asp 50 55 60 Gly Thr Phe Ser Pro Val Gly Glu Tyr Ser Ser Ala Pro Val Lys Lys 65 70 75 80 Gln Tyr Glu Tyr Pro Val Phe Ser His Val Gln Ala Gly Met Phe Ser 85 90 95 Pro Glu Leu Arg Thr Phe Thr Lys Gly Asp Ala Glu Arg Leu Val Ser 100 105 110 Thr Thr Lys Lys Ala Ser Asp Ser Ala Phe Trp Leu Glu Val Glu Gly 115 120 125 Asn Ser Met Thr Ala Pro Thr Gly Ser Lys Pro Ser Phe Pro Asp Gly 130 135 140 Met Leu Ile Leu Val Asp Pro Glu Gln Ala Val Glu Pro Gly Asp Phe 145 150 155 160 Cys Ile Ala Arg Leu Gly Gly Asp Glu Phe Thr Phe Lys Lys Leu Ile 165 170 175 Arg Asp Ser Gly Gln Val Phe Leu Gln Pro Leu Asn Pro Gln Tyr Pro 180 185 190 Met Ile Pro Cys Asn Glu Ser Cys Ser Val Val Gly Lys Val Ile Ala 195 200 205 Gly Gln Trp Pro Glu Glu Thr Phe Gly * 210 215 <210> 271 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11672..11887) <400> 271 Met Ser Asn Leu Arg Lys Tyr Arg Glu Ser Leu Asn Ile Ser Gln Thr 1 5 10 15 Thr Leu Ala Lys Ala Val Gly Cys Thr Gln Gly Ala Ile Gly His Trp 20 25 30 Glu Ser Gly Arg Arg Phe Pro Asp Leu Lys Thr Cys Arg Ala Leu Val 35 40 45 Ala Cys Leu Asn Lys Leu Gly Ala Lys Val Ser Leu Asp Asp Val Phe 50 55 60 Pro Pro Glu His Lys Ala Ala * 65 70 <210> 272 <211> 99 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12029..12325) <400> 272 Met Glu Gln Thr Ser Tyr Ser Lys Leu Ser Gln Arg Glu Ile Asp Arg 1 5 10 15 Ala Glu Thr Asp Leu Leu Ile Asn Leu Ser Thr Leu Thr Gln Arg Gly 20 25 30 Leu Ala Lys Met Ile Gly Cys His Glu Ser Lys Ile Ser Arg Thr Asp 35 40 45 Trp Arg Phe Ile Ala Ser Val Leu Cys Ala Phe Gly Met Ala Ser Asp 50 55 60 Ile Ser Pro Ile Ser Arg Ala Phe Lys Tyr Ala Leu Asp Glu Ile Thr 65 70 75 80 Lys Lys Lys Ser Pro Ala Ala Thr Glu Asp Phe Lys Gln Ile Asp Met 85 90 95 Gln Phe * <210> 273 <211> 49 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12358..12504) <400> 273 Met Thr Lys Gln Leu Ser Pro Tyr Gln Asp Lys Ile His Lys His Ile 1 5 10 15 Leu Arg Asp Arg Phe Leu Ser Ser Phe Lys Gln Pro Gly Arg Phe Arg 20 25 30 Ala Glu Leu Glu Lys Val Lys Leu Met Gln Lys Glu Lys Gly His Glu 35 40 45 * <210> 274 <211> 300 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12497..13396) <400> 274 Met Ser Asn Ile Ser Asn Leu Ala Glu Ala Arg Glu Ala Arg Arg Leu 1 5 10 15 Gln Gln Pro His Gln Ser Ser Gly Lys Gly Tyr Ala Leu Leu His Arg 20 25 30 Lys Ile Met Asp Val Pro Phe Tyr Lys Asp Ala Glu Ala Ala His Leu 35 40 45 Trp Val His Leu Ile Leu Lys Ala Lys His Thr Pro Glu Tyr Val Met 50 55 60 Thr Asp Ala Gly Glu Ile Leu Val Gly Arg Gly Lys Leu Leu Gly Gly 65 70 75 80 Arg Asn Ser Leu Ala Phe Glu Thr Gly Leu Lys Pro Asp Arg Val Gln 85 90 95 Tyr Leu Leu Arg Lys Phe Lys Lys Leu Gly Met Ile Asp Trp Val Ser 100 105 110 His Gly Lys Phe Ser Val Phe Ser Val Glu Lys Tyr Asp Asp Tyr Gln 115 120 125 Ser Asn Phe Val Pro Ala Asp Tyr Gln Gln Ile Thr Thr Ser Lys Pro 130 135 140 Ala Ile Pro Met Pro Ala Ser Asn Thr Val Pro Ala Asp Tyr Gln Gln 145 150 155 160 Ile Thr Thr Asp Lys Glu Tyr Asn Asn Ile Ile Ser Asn Thr Asp Val 165 170 175 Leu Glu Ser Ala Thr Ala Asp Lys Lys Ser Asp Lys Lys Lys Pro Ser 180 185 190 Val Ser Cys Gln Asp Val Val Asp Ala Tyr His Glu Ile Leu Pro Glu 195 200 205 Ala Pro Lys Ile Arg Ala Leu Asn Asp Lys Arg Lys Asn Gln Ile Arg 210 215 220 Thr Phe Trp Arg Lys Ala Gly Val Ile Thr Arg Gln Leu Asp Gly His 225 230 235 240 Gly Phe Thr Met Gln Asp Trp Arg Asn Tyr Leu Ser Tyr Val Gly Glu 245 250 255 Asn Cys Arg Trp Met Phe Glu Glu Arg Pro Asn His Gln Arg Gly Thr 260 265 270 Val Trp His Lys Lys Gly Phe Asp Phe Leu Leu Asn Asp Asn Thr Tyr 275 280 285 Leu Lys Val Arg Glu Gly Glu His Asp Asp Arg * 290 295 <210> 275 <211> 484 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13371..14822) <400> 275 Val Arg Val Asn Thr Met Thr Asp Asn Phe Tyr Ala Pro Pro His Ser 1 5 10 15 Ile Glu Ala Glu Gln Ala Val Ile Gly Gly Leu Leu Leu Asp Asp Asp 20 25 30 Ser Ser Glu Arg Val Gln Lys Val Leu Ala Met Leu Lys Pro Asp Ser 35 40 45 Phe Tyr Ser Arg Pro His Lys Ile Ile Phe Glu Glu Ile Thr Arg Met 50 55 60 His Arg Glu Gln Lys Pro Val Asp Gly Leu Thr Leu Phe Asp Glu Leu 65 70 75 80 Glu Arg Lys Ser Leu Thr Ala Ser Val Gly Gly Phe Ala Tyr Ile Ala 85 90 95 Glu Ile Ala Lys Asn Thr Pro Ser Ala Ala Asn Ile Val Ala Tyr Ala 100 105 110 Met Gln Val Arg Glu Thr Ala Met Glu Arg Tyr Ala Ile Asn Arg Met 115 120 125 Thr Glu Ala Thr Glu Leu Leu Tyr Ser Arg Asn Gly Met Thr Ala Thr 130 135 140 Gln Lys Tyr Glu Ala Ile Gln Ala Ile Phe Thr Gln Leu Thr Asp His 145 150 155 160 Ala Lys Thr Gly Ser Arg Arg Gly Leu Arg Ser Phe Gly Glu Val Met 165 170 175 Glu Asp Trp Val Ser Asp Leu Glu Lys Arg Phe Asp Pro Ser Gly Glu 180 185 190 Gln Arg Gly Met Ser Thr Gly Ile Pro Ser Leu Asp Arg Met Leu Ser 195 200 205 Pro Lys Gly Leu Val Lys Gly Ser Leu Phe Val Ile Gly Ala Arg Pro 210 215 220 Lys Met Gly Lys Thr Thr Leu Tyr Ser Gln Met Ala Ile Asn Cys Ala 225 230 235 240 Val His Glu Lys Lys Pro Ala Leu Met Phe Ser Leu Glu Met Pro Gly 245 250 255 Asp Gln Ile Leu Glu Lys Leu Val Gly Gln Lys Ser Gly Val Asn Pro 260 265 270 Asn Ile Phe Tyr Leu Pro Ala Thr Asn Asp Ala Asp Asp Gly Tyr Gln 275 280 285 Gly Asp Tyr Asp Gly Asp Phe Asn Arg Ala Ile Glu Thr Ala Asn Arg 290 295 300 Leu Ser Glu Ile Asp Leu Leu Tyr Ile Asp Asp Thr Pro Gly Leu Ser 305 310 315 320 Leu Ala Gln Ile Val Ser Glu Ser Arg Arg Ile Lys Arg Glu Lys Gly 325 330 335 Cys Val Gly Met Ile Leu Val Asp Tyr Leu Thr Leu Met Thr Ala Glu 340 345 350 Lys Ala Asp Arg Asn Asp Leu Ala Tyr Gly Met Ile Thr Lys Gly Leu 355 360 365 Lys Asn Leu Ala Lys Glu Leu Asp Cys Val Val Val Leu Leu Thr Gln 370 375 380 Leu Asn Arg Ala Leu Glu Ser Arg Thr Asn Lys Arg Pro Leu Pro Ser 385 390 395 400 Asp Ser Arg Asp Thr Gly Gln Ile Glu Gln Asp Cys Asp Tyr Trp Val 405 410 415 Gly Ile His Arg Glu Gly Ala Phe Asp Asp Ser Val Pro Pro Gly Glu 420 425 430 Thr Glu Leu Ile Leu Arg Leu Asn Arg His Gly Asn Thr Gly Thr Val 435 440 445 Tyr Cys Ile Gln Ala Asn Gly Ala Ile Tyr Asp Thr Asp Gln Gln Ser 450 455 460 Ala Glu Met Arg Arg Arg Glu Arg Glu Glu Pro Gln Ser Lys Lys Lys 465 470 475 480 Gly Gly Phe * <210> 276 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14822..15091) <400> 276 Met Asn Lys Lys Gln Leu Ala Ile Leu Glu Lys Ala Trp Asp Ala Gln 1 5 10 15 Ile Ser Tyr Ala Leu Lys Glu Gln Ala Leu Pro Ile Ile Gln Thr Lys 20 25 30 Ser Lys Ile Ala Arg Gln Leu Cys Asp Gly Gly Phe Leu Asn Glu Ile 35 40 45 Glu Ile Thr Arg Gln Met Val Thr Phe Lys Gly Tyr Glu Ile Asn His 50 55 60 His Gly Ile Ala Ala Tyr Cys Ser His Leu Pro Asp Asp Val Asp Ile 65 70 75 80 Asp Glu Met Glu Arg Glu Met Lys Gln * 85 <210> 277 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15162..15440) <400> 277 Val Asn Asp Ser Tyr Arg Gln Phe Glu Asn Trp Trp Ser Lys Asp Lys 1 5 10 15 Ser Gln Phe Thr Gly Asp Asp Glu Leu Lys Glu Phe Ala Trp Val Ile 20 25 30 Trp Gln Ala Ser Arg Ser Ala Ile Glu Leu Asp Ile Asp Trp Pro Glu 35 40 45 Ser Asn Asp Asp Phe Trp Lys Asp Gly Glu Glu Gly Ala Tyr Ala Met 50 55 60 Gly Tyr Glu Asp Gly Arg Asp Lys Thr Val Ile Ala Val Met Lys Ala 65 70 75 80 Ile Arg Ala Ala Gly Ile Lys Glu Lys Asn Phe Asp * 85 90 <210> 278 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15573..15788) <400> 278 Met Ser Thr Ile Ala Glu Leu Val Arg Ala Asn Phe Arg Glu Glu Leu 1 5 10 15 Val Arg Trp Tyr Arg Tyr Arg Ser Ser Ser Ser Leu Pro Leu Asp Glu 20 25 30 Leu Tyr Glu His Ser Pro Ala Ala Arg Arg Tyr Pro Arg Asp Arg Val 35 40 45 Leu Arg Arg Leu Phe Lys Leu Asn Asn Glu Phe Gln Arg Asn Arg Ile 50 55 60 Ile Arg Ser Leu Asp Leu Lys * 65 70 <210> 279 <211> 79 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15799..16035) <400> 279 Met Ser Asp Leu Ser Leu Thr Gln Pro Lys Leu Lys Glu Cys Pro Phe 1 5 10 15 Cys Gly Gly Asn Ala Arg Leu Trp Val Glu Ala Gly Ile Asn Ile Asp 20 25 30 Val Trp Gly Tyr Ala Glu Cys Asp Leu Cys Glu Ala Arg Gly Ala Trp 35 40 45 Ala Pro Ser Val Ala Ala Ala Ala Glu Lys Trp Asn Arg Arg Ala Gly 50 55 60 Asp Glu Ala Asn Leu Ser Ala Ser Gln Arg Ser Asn Gln Lys * 65 70 75 <210> 280 <211> 149 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15992..16438) <400> 280 Met Lys Gln Thr Phe Leu Leu Arg Asn Glu Ala Ile Arg Asn Asn Ala 1 5 10 15 Ile Asp Ala Ile Leu Ser Leu Pro Ile Asp Asp Lys Ser Pro His Glu 20 25 30 Val His Val Lys Glu Pro Lys Arg Ser Lys Ala Gln Asn Asp Arg Met 35 40 45 Trp Pro Met Leu Asn Asp Val Ser Arg Gln Val Leu Trp His Gly Gln 50 55 60 Arg Leu Ala Pro Glu Asp Trp Lys Asp Leu Phe Thr Ala Leu Trp Leu 65 70 75 80 Lys Thr Lys Lys Leu Glu Gln Arg Ser Val Pro Gly Ile Asp Gly Gly 85 90 95 Val Val Met Leu Gly Val Arg Thr Ser Lys Met Arg Lys Ala Ser Met 100 105 110 Thr Glu Leu Ile Glu Ile Met Phe Trp Phe Gly Ser Glu Arg Asn Val 115 120 125 Arg Trp Ser Asp Asp Ser Arg Arg Glu Tyr Glu Trp Ser Gln Arg Lys 130 135 140 Gly Arg Ala Ala * 145 <210> 281 <211> 176 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16435..16962) <400> 281 Met Thr Ile Lys Ser Asn Thr Pro Ala His Asp Lys Asp Cys Trp Gln 1 5 10 15 Thr Pro Leu Trp Leu Phe Asp Ala Leu Asp Ile Glu Phe Gly Phe Trp 20 25 30 Leu Asp Ser Ala Ala Ser Asp Lys Asn Ala Leu Cys Ala His Trp Leu 35 40 45 Thr Glu Ala Asp Asp Ala Leu Asn Ser Glu Trp Val Ser His Gly Ala 50 55 60 Ile Trp Asn Asn Pro Pro Tyr Ser Asn Ile Arg Pro Trp Val Glu Lys 65 70 75 80 Ala Ala Glu Gln Cys Ile Gln Gln Arg Gln Thr Val Val Met Leu Val 85 90 95 Pro Glu Asp Met Ser Val Gly Trp Phe Ser Lys Ala Leu Glu Ser Val 100 105 110 Asp Glu Val Arg Ile Ile Thr Asp Gly Arg Ile Asn Phe Ile Glu Pro 115 120 125 Ser Thr Gly Leu Glu Lys Lys Gly Asn Ser Lys Gly Ser Met Leu Leu 130 135 140 Ile Trp Arg Pro Phe Ile Ser Pro Arg Arg Met Phe Thr Thr Val Ser 145 150 155 160 Lys Ala Ala Leu Met Ala Ile Gly Gln Gly Val Arg Arg Ala Ala * 165 170 175 <210> 282 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16959..17141) <400> 282 Met Arg Arg Gln Arg Arg Ser Ile Thr Asp Ile Ile Cys Glu Asn Cys 1 5 10 15 Lys Tyr Leu Pro Thr Lys Arg Ser Arg Asn Lys Arg Lys Pro Ile Pro 20 25 30 Lys Glu Ser Asp Val Lys Thr Phe Asn Tyr Thr Ala His Leu Trp Asp 35 40 45 Ile Arg Trp Leu Arg His Arg Ala Arg Lys Thr Arg * 50 55 60 <210> 283 <211> 58 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17246..17419) <400> 283 Val Phe Phe Ile Val Val Cys Thr Arg Thr Ser Glu Leu Trp Trp Ala 1 5 10 15 Val Trp Gly Arg Arg Asp Pro Arg Arg Ser Val Ser Arg Leu Arg Gln 20 25 30 Pro Cys Thr Val His His Gln Thr Ile Gly Val Val Gly Gly Glu Leu 35 40 45 Leu Arg Asn His Gln Arg Ala Ser Leu * 50 55 <210> 284 <211> 245 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17416..18150) <400> 284 Met Thr Thr Gln Ile Ser Val Glu Thr Leu Ser Pro Ile Thr His Asn 1 5 10 15 Gln Ile Pro Val Ile Thr Thr Glu Leu Leu Ala Gln Leu Tyr Gly Thr 20 25 30 Glu Pro Val Arg Ile Arg Gln Asn His His Glu Asn Lys Val Arg Phe 35 40 45 Val Glu Gly Lys His Phe Phe Lys Val Val Gly Asn Asp Leu Lys Glu 50 55 60 Leu Arg Val Ala Leu Asn Tyr Ser Gln Asn Leu Arg Val Thr Leu Ser 65 70 75 80 Asn Ser Gln Asn Leu Gln Pro Ser Leu Arg Gly Leu Gln Ile Ser Pro 85 90 95 Lys Ala Arg Ser Leu Ile Leu Trp Thr Glu Arg Gly Ala Ala Arg His 100 105 110 Ala Lys Met Leu Glu Thr Asp Gln Ala Trp Asp Val Phe Glu Lys Leu 115 120 125 Glu Asp Cys Tyr Phe Ser Gln Cys Glu Lys Asn Thr Gly Lys Gln Glu 130 135 140 Lys Lys Leu Asn Gly Leu Ser Ala Lys Glu Thr Asp Ser Leu Val Trp 145 150 155 160 Leu Trp Asp Tyr Ala Asn Arg Ser Gln Ala Leu Phe Arg Glu Leu Tyr 165 170 175 Pro Ala Leu Lys Leu Ile Gln Ser Gly Tyr Ser Gly Ile Cys His Asp 180 185 190 Tyr Gly Tyr Glu Phe Ser Tyr Ile Ile Gly Arg Ala Arg Gly Val Leu 195 200 205 Ile Asn His Thr Arg Asp Ile Asp Ile Tyr Glu Pro Asp Gly Pro Thr 210 215 220 Asn Leu Leu Ala Trp Glu Arg Leu Lys Asn Lys Glu Leu Pro Pro Ser 225 230 235 240 Leu His Arg Tyr * <210> 285 <211> 241 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18225..18947) <400> 285 Met Asn Glu Leu Ile Asn Ser Asn Ala Ile Lys Met Thr Ser Ile Glu 1 5 10 15 Ile Ala Glu Leu Val Gly Ser Arg His Asp Lys Val Lys Gln Ser Ile 20 25 30 Glu Arg Leu Ala Val Arg Gly Val Ile Arg Asn Pro Pro Met Val Val 35 40 45 Phe Glu Lys Ile Asn Asn Leu Gly Leu Leu Arg Gly Val Glu Ala Tyr 50 55 60 Val Phe Glu Gly Glu Gln Gly Lys Arg Asp Ser Ile Ile Val Val Ala 65 70 75 80 Gln Leu Ser Pro Glu Phe Thr Ala Arg Leu Val Asp Arg Trp Arg Glu 85 90 95 Leu Glu Gly Ala Thr Ala Lys Ile Pro Gln Thr Phe Ser Glu Ala Leu 100 105 110 Arg Leu Ala Ala Asp Leu Glu Asp Gln Lys Ala Glu Leu Glu Lys Gln 115 120 125 Leu Ala Leu Ala Ala Pro Lys Val Glu Phe Ala Asp Arg Val Gly Glu 130 135 140 Ala Ser Gly Ile Leu Ile Gly Asn Phe Ala Lys Val Val Gly Ile Gly 145 150 155 160 Pro Asn Lys Leu Phe Ala Trp Met Arg Asp His Lys Ile Leu Ile Ala 165 170 175 Ser Gly Ser Arg Arg Asn Val Pro Met Gln Glu Tyr Met Asp Arg Gly 180 185 190 Tyr Phe Thr Val Lys Glu Thr Ala Val Asn Thr Asn His Gly Ile Gln 195 200 205 Ile Ser Phe Thr Thr Lys Ile Thr Gly Arg Gly Gln Gln Trp Leu Thr 210 215 220 Arg Lys Leu Leu Asp Asn Gly Met Leu Lys Val Thr Arg Glu Ala Ala 225 230 235 240 * <210> 286 <211> 202 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18947..19552) <400> 286 Met Ala Lys Pro Ala Arg Arg Lys Cys Lys Ile Cys Lys Glu Trp Phe 1 5 10 15 His Pro Ala Phe Ser Asn Gln Trp Trp Cys Cys Pro Glu His Gly Thr 20 25 30 Gln Leu Ala Leu Glu Arg Arg Ser Lys Glu Arg Glu Lys Ala Glu Lys 35 40 45 Ala Ala Glu Lys Lys Arg Arg Arg Glu Glu Gln Lys Gln Lys Asp Lys 50 55 60 Leu Lys Ile Arg Lys Leu Ala Leu Lys Pro Arg Ser Tyr Trp Ile Lys 65 70 75 80 Gln Ala Gln Gln Ala Val Asn Ala Phe Ile Arg Glu Arg Asp Arg Asp 85 90 95 Leu Pro Cys Ile Ser Cys Gly Thr Leu Thr Ser Ala Gln Trp Asp Ala 100 105 110 Gly His Tyr Arg Thr Thr Ala Ala Ala Pro Gln Leu Arg Phe Asp Glu 115 120 125 Arg Asn Ile His Lys Gln Cys Val Val Cys Asn Gln His Lys Ser Gly 130 135 140 Asn Leu Val Pro Tyr Arg Val Glu Leu Ile Asn Arg Ile Gly Gln Glu 145 150 155 160 Ala Val Asp Glu Ile Glu Ser Asn His Asn Arg His Arg Trp Thr Val 165 170 175 Glu Glu Cys Arg Ala Ile Lys Ala Lys Tyr Gln Gln Lys Leu Lys Asp 180 185 190 Leu Arg Asn Ser Arg Ser Glu Ala Ala * 195 200 <210> 287 <211> 65 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19549..19743) <400> 287 Met Thr Phe Thr Val Lys Thr Ile Pro Asp Met Leu Val Glu Ala Tyr 1 5 10 15 Glu Asn Gln Thr Glu Val Ala Arg Ile Leu Asn Cys Ser Arg Asn Thr 20 25 30 Val Arg Lys Tyr Thr Gly Asp Lys Glu Gly Lys Arg His Ala Ile Val 35 40 45 Asn Gly Val Leu Met Val His Arg Gly Trp Gly Lys Asp Thr Asp Ala 50 55 60 * <210> 288 <211> 145 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19736..20170) <400> 288 Met Arg Asp Ile Arg Gln Val Leu Glu Arg Trp Gly Ala Trp Ala Ala 1 5 10 15 Asn Asn Tyr Glu Asp Val Thr Trp Ser Pro Ile Ala Ala Gly Phe Lys 20 25 30 Gly Leu Ile Pro Glu Lys Val Lys Ser Arg Pro Gln Cys Cys Asp Asp 35 40 45 Asp Ala Met Val Ile Cys Gly Cys Ile Ala Arg Leu Tyr Arg Asn Asn 50 55 60 Arg Asp Leu His Asp Leu Leu Val Asp Tyr Tyr Val Leu Gly Glu Thr 65 70 75 80 Phe Met Ala Leu Ala Arg Lys His Gly Cys Ser Asp Thr Cys Ile Gly 85 90 95 Lys Arg Leu His Lys Ala Glu Gly Ile Val Glu Gly Met Leu Met Met 100 105 110 Leu Gly Val Arg Leu Glu Met Asp Arg Tyr Val Glu Arg Glu Leu Pro 115 120 125 Gly Gly Arg Thr Ser Val Phe Tyr Gln Arg Lys Asn Ser Leu Arg Ser 130 135 140 * <210> 289 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20419..20571) <400> 289 Leu Pro Ala Ser Pro Ser Gly Trp Leu Phe Tyr Val Arg Ser Val Lys 1 5 10 15 Ala Ala Met Ala Leu Gly Arg Arg Ala Ile Gly Val Glu Leu Glu Ser 20 25 30 Gly Arg Phe Glu Gln Thr Val Arg Glu Val Gln Asn Val Val Ser Gln 35 40 45 Asn Gly * 50 <210> 290 <211> 320 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20954..21913) <400> 290 Met Lys Cys Ile Leu Phe Lys Trp Val Leu Cys Leu Leu Leu Gly Phe 1 5 10 15 Ser Ser Val Ser Tyr Ser Arg Glu Phe Thr Ile Asp Phe Ser Thr Gln 20 25 30 Gln Ser Tyr Val Ser Ser Leu Asn Ser Ile Arg Thr Glu Ile Ser Thr 35 40 45 Pro Leu Glu His Ile Ser Gln Gly Thr Thr Ser Val Ser Val Ile Asn 50 55 60 His Thr Pro Pro Gly Ser Tyr Phe Ala Val Asp Ile Arg Gly Leu Asp 65 70 75 80 Val Tyr Gln Ala Arg Phe Asp His Leu Arg Leu Ile Ile Glu Gln Asn 85 90 95 Asn Leu Tyr Val Ala Gly Phe Val Asn Thr Ala Thr Asn Thr Phe Tyr 100 105 110 Arg Phe Ser Asp Phe Thr His Ile Ser Val Pro Gly Val Thr Thr Val 115 120 125 Ser Met Thr Thr Asp Ser Ser Tyr Thr Thr Leu Gln Arg Val Ala Ala 130 135 140 Leu Glu Arg Ser Gly Met Gln Ile Ser Arg His Ser Leu Val Ser Ser 145 150 155 160 Tyr Leu Ala Leu Met Glu Phe Ser Gly Asn Thr Met Thr Arg Asp Ala 165 170 175 Ser Arg Ala Val Leu Arg Phe Val Thr Val Thr Ala Glu Ala Leu Arg 180 185 190 Phe Arg Gln Ile Gln Arg Glu Phe Arg Gln Ala Leu Ser Glu Thr Ala 195 200 205 Pro Val Tyr Thr Met Thr Pro Gly Asp Val Asp Leu Thr Leu Asn Trp 210 215 220 Gly Arg Ile Ser Asn Val Leu Pro Glu Tyr Arg Gly Glu Asp Gly Val 225 230 235 240 Arg Val Gly Arg Ile Ser Phe Asn Asn Ile Ser Ala Ile Leu Gly Thr 245 250 255 Val Ala Val Ile Leu Asn Cys His His Gln Gly Ala Arg Ser Val Arg 260 265 270 Ala Val Asn Glu Glu Ser Gln Pro Glu Cys Gln Ile Thr Gly Asp Arg 275 280 285 Pro Val Ile Lys Ile Asn Asn Thr Leu Trp Glu Ser Asn Thr Ala Ala 290 295 300 Ala Phe Leu Asn Arg Lys Ser Gln Phe Leu Tyr Thr Thr Gly Lys * 305 310 315 <210> 291 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21925..22194) <400> 291 Met Lys Lys Met Phe Met Ala Val Leu Phe Ala Leu Ala Ser Val Asn 1 5 10 15 Ala Met Ala Ala Asp Cys Ala Lys Gly Lys Ile Glu Phe Ser Lys Tyr 20 25 30 Asn Glu Asp Asp Thr Phe Thr Val Lys Val Asp Gly Lys Glu Tyr Trp 35 40 45 Thr Ser Arg Trp Asn Leu Gln Pro Leu Leu Gln Ser Ala Gln Leu Thr 50 55 60 Gly Met Thr Val Thr Ile Lys Ser Ser Thr Cys Glu Ser Gly Ser Gly 65 70 75 80 Phe Ala Glu Val Gln Phe Asn Asn Asp * 85 <210> 292 <211> 635 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22681..24585) <400> 292 Met Ala Phe Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Lys Arg Ile Thr Gln Lys Leu Lys Glu Gly Trp Gln Pro Tyr 20 25 30 Gly Ser Ala Leu Ile Ser Thr Ala Gly Tyr Gly Ala Glu Phe Ile Gln 35 40 45 Pro Val Val Ser Glu Gly Ser Ile Ser Ser Pro Glu Glu Pro Gly Asn 50 55 60 Arg Pro Thr Thr Ser Ala Pro Ser Val Ala Pro Glu Tyr Tyr Tyr Val 65 70 75 80 Ile Ala Leu Ala Gly Gln Ser Asn Gly Met Ser Tyr Gly Glu Gly Leu 85 90 95 Pro Leu Pro Asp Thr Phe Asp Ser Pro Asp Pro Arg Ile Lys Gln Leu 100 105 110 Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Ala Val Cys Lys Tyr Asn 115 120 125 Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln Asp Met Ser 130 135 140 Arg Leu Asn His Pro Lys Ala Asp Leu Ser Lys Gly Gln Tyr Gly Thr 145 150 155 160 Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro Phe Ile Pro 165 170 175 Ala Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly Gly Ser Ala 180 185 190 Phe Thr Thr Gly Ala Asp Gly Thr Tyr Ser Asp Ala Ser Gly Ala Ser 195 200 205 Glu Asn Ser Thr Arg Trp Gly Val Asp Lys Pro Leu Tyr Lys Asp Leu 210 215 220 Ile Gly Arg Thr Lys Ala Ala Leu Lys Lys Asn Pro Lys Asn Val Leu 225 230 235 240 Phe Ala Val Val Trp Met Gln Gly Glu Phe Asp Phe Gly Gly Thr Pro 245 250 255 Val Asn His Ala Ala Gln Phe Gly Ala Leu Val Asp Lys Phe Arg Ala 260 265 270 Asp Leu Ala Asp Met Ala Gly Gln Cys Val Gly Gly Ser Ala Gly Gly 275 280 285 Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Phe Trp Lys Gln Lys Asn 290 295 300 Glu Ser Thr Tyr Gln Thr Val Tyr Gly Ser Tyr Lys Asn Lys Thr Glu 305 310 315 320 Lys Asn Ile His Phe Val Pro Phe Met Thr Asp Glu Asn Gly Val Asn 325 330 335 Val Pro Thr Asn Lys Pro Glu Glu Asp Pro Asp Ile Pro Gly Ile Gly 340 345 350 Tyr Tyr Gly Ser Lys Trp Arg Asp Ser Ser Ala Thr Trp Thr Ser Gln 355 360 365 Asp Arg Ala Ser His Phe Ser Ser Trp Ala Arg Arg Gly Ile Ile Ser 370 375 380 Asp Arg Leu Ala Thr Ala Ile Leu Arg His Ala Gly Arg Val Ala Leu 385 390 395 400 Asn Ala Gly Ala Ser Ser Thr Val Ser Glu Val Arg Pro Ser Ser Pro 405 410 415 Ser Gly Ala Glu Ala Thr Gly Val Thr Thr Leu Leu Ser Tyr Leu Ala 420 425 430 Ser Glu Ser Glu Gly Ser Leu Lys Val Gln Gly Trp Ser Ala Ser Gly 435 440 445 Gly Arg Ala Glu Val Val Ser Asp Ala Glu Gly Thr Gly Gly Lys Ala 450 455 460 Val Lys Leu Thr Lys Glu Ala Gly Lys Ser Ser Trp Val Leu Glu Tyr 465 470 475 480 Ala Ala Gly Asn Gly Ala Ala Leu Leu Gln Lys Gly Gly Gln Ile Arg 485 490 495 Cys Arg Phe Lys Val Ser Gly Ala Leu Ala Ala Asn Gln Tyr Val Met 500 505 510 Ala Phe Tyr Trp Pro Val Ser Ser Leu Pro Gln Gly Val Ala Leu Thr 515 520 525 Gly Asp Gly Gly Asn Asn Leu Leu Ala Ala Phe Tyr Ile Gln Thr Asp 530 535 540 Ala Lys Asp Leu Asn Val Met Tyr His Asn Ala Lys Val Asn Arg Pro 545 550 555 560 Gly Phe Pro Gly Glu Cys Phe Ile Cys Glu Leu Arg Leu Pro Asp His 565 570 575 Arg Phe Arg Trp Lys His Asn Lys Leu Phe Leu Leu Leu Pro Glu Glu 580 585 590 Tyr Gly Pro Ala Phe Pro Ala Ile Val Asp Cys Tyr Thr Ser Pro Pro 595 600 605 Thr Leu Val Trp Pro Val Pro Leu Leu His Gly Phe Ser Ser Ser Tyr 610 615 620 Gly Val Leu Pro Pro Leu Cys Lys Asp His * 625 630 <210> 293 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24392..25282) <400> 293 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 294 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25279..25605) <400> 294 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 295 <211> 60 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26067..26246) <400> 295 Met Thr Phe Leu Asn Gln Leu Met Leu Tyr Phe Cys Thr Val Val Cys 1 5 10 15 Val Leu Tyr Leu Leu Ser Gly Gly Tyr Arg Ala Met Arg Asp Phe Trp 20 25 30 Arg Arg Gln Ile Asp Lys Arg Ala Ala Glu Lys Ile Ser Ala Ser Gln 35 40 45 Ser Ala Gly Ser Lys Pro Glu Glu Pro Leu Ile * 50 55 <210> 296 <211> 149 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26113..26559) <400> 296 Val Cys Cys Ile Ser Phe Arg Val Gly Thr Gly Pro Cys Val Thr Ser 1 5 10 15 Gly Ala Asp Arg Leu Thr Lys Gly Pro Leu Arg Lys Ser Ala Pro Val 20 25 30 Ser Gln Pro Glu Ala Asn Pro Lys Ser Arg Ser Phe Ser Gly Asn Phe 35 40 45 Leu Asn His Thr Phe Arg Arg Glu Asn Pro Met Ser Glu Ile Thr Ser 50 55 60 Leu Val Thr Ala Glu Ala Val Lys Asp Val Leu Arg Ser Glu Glu Val 65 70 75 80 Arg Ser Ala Leu Lys Gln Lys Leu Arg His Asn Leu Glu Ala Arg Leu 85 90 95 Asp Ala Glu Val Asp Ala Ile Leu Asp Glu Leu Leu Gly Val Gln Ala 100 105 110 Glu Pro Pro Thr Glu Ala Gly Asp Thr Thr Ala Glu Ser Gly Glu Val 115 120 125 Gln Pro Glu Ser Pro Val Ala Asp Ala Thr Glu Pro Gln Pro Glu Ser 130 135 140 Val Met Met Leu * 145 <210> 297 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26636..26851) <400> 297 Met Tyr Gln Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser 1 5 10 15 Ala Val Gly Thr Gly Tyr Trp Phe Leu Gln Leu Leu Asp Arg Val Ser 20 25 30 Pro Ser Gln Trp Ala Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly 35 40 45 Leu Leu Thr Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Lys Glu Asp Arg 50 55 60 Arg Lys Ala Ala Arg Gly Glu * 65 70 <210> 298 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26856..27389) <400> 298 Met Ser Arg Lys Leu Arg Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Ala Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Thr Arg Val Asp Gly Lys Pro Val Ile 50 55 60 Pro Gly Met Lys Leu Ser Lys Glu Lys Cys Asp Arg Val Asn Ala Ile 65 70 75 80 Glu Arg Asp Lys Ala Leu Ala Trp Val Glu Lys Asn Ile Lys Val Pro 85 90 95 Leu Thr Glu Pro Gln Lys Ala Gly Ile Ala Ser Phe Cys Pro Tyr Asn 100 105 110 Ile Gly Pro Gly Lys Cys Phe Pro Ser Thr Phe Tyr Arg Arg Ile Asn 115 120 125 Ala Gly Asp Arg Lys Gly Ala Cys Glu Ala Ile Arg Trp Trp Ile Lys 130 135 140 Asp Gly Gly Arg Asp Cys Arg Ile Arg Ser Asn Asn Cys Tyr Gly Gln 145 150 155 160 Val Ser Arg Arg Asp Gln Glu Ser Ala Leu Ala Cys Trp Gly Ile Asp 165 170 175 Arg * <210> 299 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27660..28229) <400> 299 Met Asn Met Met Ala Val Pro Phe His Gly Asn Ser Leu Tyr Val Val 1 5 10 15 Asn His Asn Gly Glu Pro Tyr Val Pro Met Lys Pro Val Val Ala Gly 20 25 30 Met Gly Leu Ala Trp Gln Ser Gln Leu Ala Lys Leu Arg Gln Arg Phe 35 40 45 Ala Ser Thr Ile Thr Glu Ile Val Met Val Ala Glu Asp Gly Lys Gln 50 55 60 Arg Asn Met Val Ser Met Pro Leu Arg Lys Leu Ala Gly Trp Leu Gln 65 70 75 80 Thr Ile Asn Pro Asn Lys Val Lys Pro Glu Ile Arg Asp Lys Val Ile 85 90 95 Arg Tyr Gln Glu Glu Cys Asp Asp Val Leu Tyr Glu Tyr Trp Thr Lys 100 105 110 Gly Phe Val Val Asn Pro Arg Lys Met Ser Val Met Glu Glu Leu Asn 115 120 125 Gln Ala Cys Ala Asp Met Lys Arg Asp Lys Asn Ile Ala Ser Val Phe 130 135 140 Ala Thr Gly Leu Asn Glu Trp Lys Gln Val Lys Ala Ala His Val Ser 145 150 155 160 Lys Ile Arg Thr Leu Val Asn Glu Ala Asn Met Leu Ile Asp Phe Val 165 170 175 Leu Ala Asp Thr Gly Lys Gly Lys Ile Thr Lys Ala Asp * 180 185 <210> 300 <211> 155 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28383..28847) <400> 300 Met Asn Arg Val Leu Cys Val Val Ile Ile Val Leu Ala Val Gly Tyr 1 5 10 15 Gly Ala Leu Trp Leu Ala Thr Asn His Tyr Arg Asp Asn Ala Leu Thr 20 25 30 Tyr Lys Ala Gln Arg Asp Lys Lys Ala Arg Glu Leu Glu Gln Ala Asn 35 40 45 Ala Thr Ile Thr Asp Met Gln Val Arg Gln Arg Asp Val Ala Ala Leu 50 55 60 Asp Ala Lys Tyr Ser Arg Glu Leu Ala Asp Ala Arg Ala Glu Asn Glu 65 70 75 80 Thr Leu Arg Ala Asp Val Ala Ala Gly Arg Lys Arg Leu Arg Ile Asn 85 90 95 Ala Thr Cys Ser Gly Thr Val Arg Glu Ala Thr Gly Thr Ser Gly Val 100 105 110 Asp Asn Ala Thr Gly Pro Arg Leu Ala Asp Thr Ala Glu Arg Asp Tyr 115 120 125 Phe Ile Leu Arg Glu Arg Leu Ile Thr Met Gln Lys Gln Leu Glu Gly 130 135 140 Thr Gln Lys Tyr Ile Asn Glu Gln Cys Arg * 145 150 <210> 301 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28603..28788) <400> 301 Met Arg Glu Leu Lys Met Lys Leu Cys Val Leu Met Leu Pro Leu Val 1 5 10 15 Val Ser Ala Cys Gly Ser Thr Pro Pro Ala Pro Val Pro Cys Val Lys 20 25 30 Pro Pro Ala Pro Pro Ala Trp Ile Met Gln Pro Ala Pro Asp Trp Gln 35 40 45 Thr Pro Leu Asn Gly Ile Ile Ser Ser Ser Glu Arg Gly * 50 55 60 <210> 302 <211> 98 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28879..29172) <400> 302 Met Lys Lys Met Leu Leu Ala Thr Ala Leu Ala Leu Leu Ile Thr Gly 1 5 10 15 Cys Ala Gln Gln Thr Phe Thr Val Gln Asn Lys Gln Thr Ala Val Ala 20 25 30 Pro Lys Glu Thr Ile Thr His His Phe Phe Val Ser Gly Ile Gly Gln 35 40 45 Lys Lys Thr Val Asp Ala Ala Lys Ile Cys Gly Gly Thr Glu Asn Val 50 55 60 Val Lys Thr Glu Thr Gln Gln Thr Phe Val Asn Gly Leu Leu Gly Phe 65 70 75 80 Ile Thr Leu Gly Ile Tyr Thr Pro Leu Glu Ala Arg Val Tyr Cys Ser 85 90 95 Gln * <210> 303 <211> 78 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29292..29525) <400> 303 Met Asn Arg His Cys Ile Pro Gly Leu Thr Met Ser Thr Ala Leu Thr 1 5 10 15 Gly Asn Phe Ser Ala Gly Val Cys Gly Asp Asn Gln Lys Arg Cys Thr 20 25 30 Pro Gly Phe Leu Ile Phe His Glu Met Gly Ala Ile Ser Arg Glu Ala 35 40 45 Ala Cys Pro Val Arg Trp Trp Lys Lys Pro Asp Lys Thr Thr Ala Leu 50 55 60 Cys Lys Tyr Arg Ser Asn Met Val Leu Leu Cys Glu Ile * 65 70 75 <210> 304 <211> 269 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29581..30387) <400> 304 Met Ala Lys Leu Asp Trp Lys Lys Leu Glu Gln Ala Phe Arg Arg Glu 1 5 10 15 His Ala Glu Thr Gly Ile Thr Leu Leu Asp Trp Cys Arg Lys Lys Lys 20 25 30 Ile Asn Tyr Asn Thr Ala Arg Thr Arg Ile Lys Met Gly Lys Ile Asp 35 40 45 His Glu Ile Asp His Lys Thr Asp His Glu Ile Asp His Asp Ile Ser 50 55 60 Asp Glu Glu Pro Cys Asn Asp Ala Gly Ser Gly Asp Glu Lys Cys Ala 65 70 75 80 Lys Asn Ser Glu Lys Asn Cys Ala Asn Ser Ala Glu Thr Lys Arg Ile 85 90 95 Arg Gly Ser Arg Leu Leu Pro Pro Ser Asn Ala Phe Ser Gln Arg Asn 100 105 110 Thr His Ala Val Arg His Arg Gly Tyr Ala Lys Tyr Leu Glu Ala Asp 115 120 125 Asn Leu Met Asp Asp Ala Ser Asp Met Val Leu Phe Asp Glu Leu Val 130 135 140 Phe Thr Arg Ala Arg Ala Leu Ser Val Thr Lys Ala Leu Lys Gly Met 145 150 155 160 Phe Ala Asp Leu Glu Glu Ala Thr Asp Val Glu Thr Arg Val Ala Leu 165 170 175 Tyr Asp Lys Ile Leu Lys Ala Glu Gln Ala Leu Asp Arg Asn Ile Ala 180 185 190 Arg Ile Glu Ser Ile Glu Arg Ser Leu Leu Thr Leu Asp Val Leu Ala 195 200 205 Glu Thr Ala Pro Lys Leu Arg Ala Asp Arg Glu Arg Ile Asn Ala Ala 210 215 220 Arg Asp Lys Leu Arg Ala Glu Thr Asp Ile Leu Thr Asn Gln Arg Arg 225 230 235 240 Gly Val Val Thr Pro Val Ser Asp Ile Val Ser Ser Leu His Glu Met 245 250 255 Ser Asn Ser Gly Arg Leu Asp Asp Ile Pro Glu Glu * 260 265 <210> 305 <211> 569 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30368..32074) <400> 305 Met Thr Phe Arg Lys Asn Glu Pro Arg Cys Asp Glu Pro Ser Glu Met 1 5 10 15 Thr Glu Ala Glu Gln Arg Leu Phe Ile Met Thr Lys Leu Ser Asn Pro 20 25 30 Trp Trp Arg Leu Asn His Leu Tyr Lys Ile Gln Asn Glu Lys Gly Glu 35 40 45 Leu Val Thr Phe Arg Met Arg Pro Ala Gln Arg Gln Leu Phe Arg Ser 50 55 60 Met His Asn Lys Asn Ile Ile Leu Lys Ala Arg Gln Leu Gly Phe Ser 65 70 75 80 Thr Ala Ile Asp Ile Tyr Leu Leu Asp Gln Ala Leu Phe Ile Pro His 85 90 95 Leu Lys Cys Gly Ile Val Ala Gln Asp Lys Gln Ala Ala Ser Glu Ile 100 105 110 Phe Arg Thr Lys Ile Ala Val Pro Phe Asp His Leu Pro Asp Trp Leu 115 120 125 Arg Ala Ser Phe Thr Ile Val Glu Arg Arg Ser Gly Ala Ser Gly Gly 130 135 140 Tyr Ile Leu Phe Gly His Gly Ser Ser Ile Gln Val Ala Thr Ser Phe 145 150 155 160 Arg Ser Gly Thr Val Gln Arg Leu His Ile Ser Glu His Gly Lys Ile 165 170 175 Cys Ala Lys Tyr Pro Ala Lys Ala Lys Glu Leu Arg Thr Gly Thr Leu 180 185 190 Asn Ala Val Ser Asp Glu Cys Ile Ile Phe Asp Glu Ser Thr Ala Glu 195 200 205 Gly Val Gly Gly Asp Phe Tyr Glu Met Ser Asn Arg Ala Gln Glu Ile 210 215 220 Thr Ala Ser Gly Leu Leu Leu Thr Ala Gln Asp Tyr Lys Phe His Phe 225 230 235 240 Tyr Ala Trp Trp Gln Asp Pro Lys Tyr Ser Ala Arg Val Pro Glu Ser 245 250 255 Gly Leu Lys Leu Ser Arg Glu Lys Met Thr Tyr Phe Ser Ala Val Glu 260 265 270 Lys Ala Met Asn Ile Thr Leu Thr Asp Glu Gln Lys Gln Trp Tyr Ile 275 280 285 Asn Lys Glu Thr Glu Gln Arg Glu Glu Met Lys Gln Glu Phe Pro Ser 290 295 300 Thr Pro Gln Glu Ala Phe Leu Thr Ser Gly Arg Arg Val Phe Ser Ala 305 310 315 320 Glu Ser Thr Leu Gln Ala Glu Ser Phe Cys Ser Pro Pro Met Ile Val 325 330 335 Tyr Asp Ile Glu Pro Val Thr Gly Ala Lys Thr Lys Ala Gln Ser Leu 340 345 350 Arg Glu Gly Asn Lys Asn Glu Leu Gln Arg Thr Leu Met Asn Tyr Leu 355 360 365 Leu Val Trp Glu Leu Pro Asp Pro Asp Glu Glu Tyr Val Cys Gly Ala 370 375 380 Asp Thr Ala Glu Gly Leu Glu His Gly Asp Arg Ser Ser Leu Asp Val 385 390 395 400 Val Lys Arg Ser Asn Gly Glu Gln Val Ala His Trp Phe Gly His Leu 405 410 415 Asp Ala Glu Leu Phe Ala His Leu Ile Ser Gln Val Cys Arg Met Tyr 420 425 430 Asn Asn Ala Phe Val Gly Pro Glu Arg Asn Asn His Gly His Ala Val 435 440 445 Ile Leu Lys Leu Arg Glu Leu Tyr Pro Thr Arg Tyr Ile Tyr Asn Glu 450 455 460 Gln His Leu Asp Gln Ala Tyr Asp Asp Asp Thr Pro Arg Leu Gly Trp 465 470 475 480 Leu Thr Thr Arg Gln Ser Lys Pro Val Leu Thr Glu Gly Met Lys Thr 485 490 495 Leu Leu Asn Asn Gly Ile Ser Gly Ile Arg Trp Ser Gly Thr Leu Ser 500 505 510 Glu Met Asn Thr Tyr Val Tyr Asp Ala Lys Gly Ser Met Asn Ala Gln 515 520 525 Glu Gly Cys Phe Asp Asp Gln Leu Met Ser Tyr Met Ile Ala Gln Glu 530 535 540 Met Arg Ala Arg Met Pro Val Arg Val Lys Gln Lys Thr Asp Lys Arg 545 550 555 560 Arg Thr Thr His Trp Met Ala His * 565 <210> 306 <211> 715 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32074..34218) <400> 306 Met Lys Asn Glu Thr Asn Thr Met Ala Thr Lys Asn Asp Asn Gly Ala 1 5 10 15 Thr Pro Arg Phe Ser Gln Arg Gln Leu Gln Ala Leu Cys Ser Asp Ile 20 25 30 Asp Ser Gln Pro Lys Trp Arg Asp Ala Ala Asn Lys Ala Cys Ala Tyr 35 40 45 Tyr Asp Gly Asp Gln Leu Pro Pro Glu Val Leu Gln Val Leu Lys Asp 50 55 60 Arg Gly Gln Pro Met Thr Ile His Asn Leu Ile Ala Pro Thr Val Asp 65 70 75 80 Gly Val Leu Gly Met Glu Ala Lys Thr Arg Thr Asp Leu Val Val Met 85 90 95 Ser Asp Glu Pro Asp Asp Glu Thr Glu Lys Leu Ala Glu Ala Ile Asn 100 105 110 Ala Glu Phe Ala Asp Ala Cys Arg Leu Gly Asn Met Asn Lys Ala Arg 115 120 125 Ser Asp Ala Tyr Ala Glu Gln Ile Lys Ala Gly Leu Ser Trp Val Glu 130 135 140 Val Arg Arg Asn Ser Asp Pro Phe Gly Pro Glu Phe Lys Val Ser Thr 145 150 155 160 Val Ser Arg Asn Glu Val Phe Trp Asp Trp Leu Ser Arg Glu Ala Asp 165 170 175 Leu Ser Asp Cys Arg Trp Leu Met Arg Arg Arg Trp Met Asp Thr Asp 180 185 190 Glu Ala Lys Ala Thr Phe Pro Gly Met Ala Gln Val Ile Asp Tyr Ala 195 200 205 Ile Asp Asp Trp Arg Gly Phe Val Asp Thr Thr Val Thr Glu Gly Gln 210 215 220 Pro Ser Pro Leu Met Ser Ala Trp Glu Glu Tyr Gln Ser Trp Asp Arg 225 230 235 240 Gln Gln Asn Glu Trp Leu Gln Arg Glu Arg Arg Arg Val Leu Leu Gln 245 250 255 Val Val Tyr Tyr Arg Thr Phe Glu Arg Leu Pro Val Ile Glu Leu Ser 260 265 270 Asn Gly Arg Val Val Ala Phe Asp Lys Asn Asn Leu Met Gln Ala Val 275 280 285 Ala Val Ala Ser Gly Arg Val Gln Val Lys Val Gly Arg Val Ser Arg 290 295 300 Ile Arg Glu Ala Trp Phe Val Gly Pro His Phe Ile Val Asp Arg Pro 305 310 315 320 Cys Ser Ala Pro Gln Gly Met Phe Pro Leu Val Pro Phe Trp Gly Tyr 325 330 335 Arg Lys Asp Lys Thr Gly Glu Pro Tyr Gly Leu Ile Ser Arg Ala Ile 340 345 350 Pro Ala Gln Asp Glu Val Asn Phe Arg Arg Ile Lys Leu Thr Trp Leu 355 360 365 Leu Gln Ala Lys Arg Val Ile Met Asp Glu Asp Ala Thr Gln Leu Ser 370 375 380 Asp Asn Asp Leu Met Glu Gln Ile Glu Arg Pro Asp Gly Ile Ile Lys 385 390 395 400 Leu Asn Pro Val Arg Lys Asn Gln Lys Ser Val Ala Asp Val Phe Arg 405 410 415 Val Glu Gln Asp Phe Gln Val Ala Ser Gln Gln Phe Gln Val Met Gln 420 425 430 Glu Ser Glu Lys Leu Ile Gln Asp Thr Met Gly Val Tyr Ser Ala Phe 435 440 445 Leu Gly Gln Asp Ser Gly Ala Thr Ser Gly Val Ala Ile Ser Asn Leu 450 455 460 Val Glu Gln Gly Ala Thr Thr Leu Ala Glu Ile Asn Asp Asn Tyr Gln 465 470 475 480 Phe Ala Cys Gln Gln Val Gly Arg Leu Leu Leu Ala Tyr Leu Leu Asp 485 490 495 Asp Leu Lys Lys Arg Arg Asn His Ala Val Val Ile Asn Arg Asp Asp 500 505 510 Arg Gln Arg Arg Gln Thr Ile Val Leu Asn Ala Glu Gly Asp Asn Gly 515 520 525 Glu Leu Thr Asn Asp Ile Ser Arg Leu Asn Thr His Ile Ala Leu Ala 530 535 540 Pro Val Gln Gln Thr Pro Ala Phe Lys Ala Gln Leu Ala Gln Arg Met 545 550 555 560 Ser Glu Val Ile Gln Gly Leu Pro Pro Gln Val Gln Ala Val Val Leu 565 570 575 Asp Leu Trp Val Asn Leu Leu Asp Val Pro Gln Lys Gln Glu Phe Val 580 585 590 Glu Arg Ile Arg Ala Ala Leu Gly Thr Pro Lys Ser Pro Asp Glu Met 595 600 605 Thr Pro Glu Glu Gln Glu Val Ala Ala Gln Gln Gln Ala Leu Gln Gln 610 615 620 Gln Gln Ala Glu Leu Gln Met Arg Glu Met Ala Gly Arg Val Ala Lys 625 630 635 640 Leu Glu Ala Asp Ala Ala Arg Ala His Ala Ala Ala Gln Arg Asp Asn 645 650 655 Ala Ser Ala Gln Arg Glu Val Ala Leu Thr Gln Gly Gln Arg Tyr Val 660 665 670 Asp Ala Leu Asn Gln Ala His Thr Ala Glu Ile Ile Thr Gly Val Gln 675 680 685 Asn Met Glu Gln Glu Gln Asp Val Leu Gln Gln Gln Met Leu Tyr Thr 690 695 700 Leu Gln Gln Arg Met Asn Glu Met Ser Leu * 705 710 <210> 307 <211> 336 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34376..35383) <400> 307 Met Asp Phe Glu Phe Thr Gly Glu Glu Thr Pro Glu Gln Leu Glu Lys 1 5 10 15 Met Leu Glu Gly Leu Gly Asp Val Asp Ile Asp Ser His Ala Gln Asp 20 25 30 Val Val Thr Glu Asp Thr Thr Glu Lys His Ala Asp Glu Glu Ala Gln 35 40 45 Thr Gln Thr Gly Asp Asn Asn Val Ala Pro Thr Pro Asp Ala Ser Val 50 55 60 Glu Gln Thr Gln Asp Val Lys Glu Pro Glu Ala Lys Gly Val Leu Thr 65 70 75 80 Arg Asp Gly Lys His Val Ile Pro Tyr Glu Val Leu Glu Ala Glu Arg 85 90 95 Ser Gly Lys Gln Arg Ala Glu Gln Glu Ala Ala Leu Leu Arg Gly Gln 100 105 110 Ile Ala Glu Glu Lys Arg Arg Val Glu Leu Leu Thr Ser Gln Ile His 115 120 125 Gln Ala Gly Met Lys Pro Thr Pro Leu Pro Glu Asn Glu Lys Ile Ser 130 135 140 Asp Glu Gln Ile Ala Arg Ile Arg Glu Met Tyr Pro Glu Ile Gly Asp 145 150 155 160 Ala Val Ala Ser Leu Ile Arg Lys Asn Asn Tyr Leu Gln Ser Arg Val 165 170 175 Gln Gln Ser Ala Gln Gln Ala Glu Gly Asn Gly Gly Glu Asp Leu Ser 180 185 190 Pro Val Leu Asp Ala Met Asn Ala Val Pro Val Leu Lys Thr Trp Gln 195 200 205 Glu Ser Asp Pro Asp Arg Phe Ser Val Ala Val Ser Ile Asp Gly Lys 210 215 220 Leu Gln Asn Asp Pro Ala Trp Lys Asp Lys Thr Leu Thr Glu Arg Phe 225 230 235 240 Ala Glu Val Ala Arg Arg Thr Gln Val Ala Phe Gly Glu Val Ser Glu 245 250 255 Ser Ser Ala Asp Asn Lys Ala Asp Lys Thr Asp Ile Arg Lys Thr Ala 260 265 270 Glu Glu Lys Val Lys Thr Ala Glu Gln Glu Gln Ala Val Pro Ala Ser 275 280 285 Pro Ser Asp Leu Gly Thr Thr Ala Ser Val Gly Thr Gly Asp Asn Phe 290 295 300 Glu Arg Leu Leu Gly Ala Ser His Ser Glu Ala Glu Ala Ile Met Arg 305 310 315 320 Gly Met Thr Asn Ala Glu Ile Asp Ala Leu Leu Glu Lys Leu Gly * 325 330 335 <210> 308 <211> 405 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35407..36621) <400> 308 Met Thr Thr Val Thr Ser Ala Gln Ala Asn Lys Leu Tyr Gln Val Ala 1 5 10 15 Leu Phe Thr Ala Ala Asn Arg Asn Arg Ser Met Val Asn Ile Leu Thr 20 25 30 Glu Gln Gln Glu Ala Pro Lys Ala Val Ser Pro Asp Lys Lys Ser Thr 35 40 45 Lys Gln Thr Ser Ala Gly Ala Pro Val Val Arg Ile Thr Asp Leu Asn 50 55 60 Lys Gln Ala Gly Asp Glu Val Thr Phe Ser Ile Met His Lys Leu Ser 65 70 75 80 Lys Arg Pro Thr Met Gly Asp Glu Arg Val Glu Gly Arg Gly Glu Asp 85 90 95 Leu Ser His Ala Asp Phe Ser Leu Lys Ile Asn Gln Gly Arg His Leu 100 105 110 Val Asp Ala Gly Gly Arg Met Ser Gln Gln Arg Thr Lys Phe Asn Leu 115 120 125 Ala Ser Ser Ala Arg Thr Leu Leu Gly Thr Tyr Phe Asn Asp Leu Gln 130 135 140 Asp Gln Cys Ala Ile Val His Leu Ala Gly Ala Arg Gly Asp Phe Val 145 150 155 160 Ala Asp Asp Thr Ile Leu Pro Thr Ala Glu His Pro Glu Phe Lys Lys 165 170 175 Ile Met Ile Asn Asp Val Leu Pro Pro Thr His Asp Arg His Phe Phe 180 185 190 Gly Gly Asp Ala Thr Ser Phe Glu Gln Ile Glu Ala Ala Asp Ile Phe 195 200 205 Ser Ile Gly Leu Val Asp Asn Leu Ser Leu Phe Ile Asp Glu Met Ala 210 215 220 His Pro Leu Gln Pro Val Arg Leu Ser Gly Asp Glu Leu His Gly Glu 225 230 235 240 Asp Pro Tyr Tyr Val Leu Tyr Val Thr Pro Arg Gln Trp Asn Asp Trp 245 250 255 Tyr Thr Ser Thr Ser Gly Lys Asp Trp Asn Gln Met Met Val Arg Ala 260 265 270 Val Asn Arg Ala Lys Gly Phe Asn His Pro Leu Phe Lys Gly Glu Cys 275 280 285 Ala Met Trp Arg Asn Ile Leu Val Arg Lys Tyr Ala Gly Met Pro Ile 290 295 300 Arg Phe Tyr Gln Gly Ser Lys Val Leu Val Ser Glu Asn Asn Leu Thr 305 310 315 320 Ala Thr Thr Lys Glu Val Ala Ala Ala Thr Asn Ile Asp Arg Ala Met 325 330 335 Leu Leu Gly Ala Gln Ala Leu Ala Asn Ala Tyr Gly Gln Lys Ala Gly 340 345 350 Gly His Phe Asn Met Val Glu Lys Lys Thr Asp Met Asp Asn Arg Thr 355 360 365 Glu Ile Ala Ile Ser Trp Ile Asn Gly Leu Lys Lys Ile Arg Phe Pro 370 375 380 Glu Lys Ser Gly Lys Met Gln Asp His Gly Val Ile Ala Val Asp Thr 385 390 395 400 Ala Val Lys Leu * <210> 309 <211> 130 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36677..37066) <400> 309 Met Ala Lys Thr Ile Leu Ala Pro Ser Leu Ser Glu Arg Val Tyr Thr 1 5 10 15 Gly Thr His Gly Asn Glu Ser Val Ala Glu Gly Val Phe Thr Val Asn 20 25 30 Ala Ala Glu Ala Asp Ser Val Ile His Leu Leu Ser Leu Pro Val Gly 35 40 45 Ile Arg Ile Asn Ser Leu Gln Leu Val Ser Thr Gly Gly Leu Gly Thr 50 55 60 Ala Thr Val Ser Ile Lys Ser Gly Glu His Ala Leu Ile Asp Asn Ser 65 70 75 80 Glu Ala Val Ser Ala Lys Phe Ala Arg Tyr Val Pro Val Glu Pro Tyr 85 90 95 Thr Thr Gln Arg Asp Gly Glu Leu Val Thr Val Thr Ile Lys Thr Ala 100 105 110 Ala Ala Thr Gly Thr Leu Asn Val Leu Leu Arg Tyr Thr Val Val Gly 115 120 125 Tyr * <210> 310 <211> 154 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37116..37577) <400> 310 Met Ser Glu Lys Ile Ala Val Val Tyr Ile Gly Pro Lys Pro Val Lys 1 5 10 15 Lys Asp Thr Ile Thr Gly Ser Arg Thr Leu Phe Pro Arg Leu Glu Pro 20 25 30 Val His Val Asp Ser Ala Met Ala Trp Gln Leu Leu Gly Phe Pro Asp 35 40 45 Val Trp Val Arg His Glu Glu Leu Asp Asp Val Leu Lys Lys Gln Gln 50 55 60 Gln Asn Glu Gln Leu Arg Gln Ala Gln Gln Ala Gln Glu Arg Val Leu 65 70 75 80 Ala Ala Leu Ala Glu Ala Glu Asn Ser Phe Val Val Ser Val Asn Gly 85 90 95 Gln Glu Val Asp Leu Ser Lys Leu Thr Ser Ala Arg Leu Ala Thr Leu 100 105 110 Cys Glu Ala Glu Glu Leu Asp Ile His Lys Asp Pro Lys Glu Thr Ala 115 120 125 Glu Ala Phe Arg Ile Arg Val Arg Glu Ala Phe Arg Arg Arg Val Ala 130 135 140 Glu Thr Glu Gln His Gly Gly Thr Glu * 145 150 <210> 311 <211> 188 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37561..38124) <400> 311 Met Ala Glu Leu Ser Asp Phe Leu Pro Tyr Val Arg Arg His Ile Ser 1 5 10 15 Gly Pro Leu Asn Ile Met Met Thr Asp Ala Leu Ser Met Ala Ala Val 20 25 30 Ala Phe Ser Arg Gln Ser Leu Val Cys Arg Arg Glu Val Thr Val Val 35 40 45 Pro Val Ala Gly Lys Glu Ile Val Leu Pro Tyr Asp Lys Asp Asp Glu 50 55 60 Glu Cys Val His Ile Ile Arg Ile Ser Asp Asp Asn His Glu Leu Phe 65 70 75 80 Val Gly Arg Asp Val Asp Ile Ser Ser Gly Arg Ser Leu Arg Phe Ala 85 90 95 Cys Ser Pro Gly Glu Val Ser Val Leu Tyr Ala Val Ala Pro Lys Ala 100 105 110 Gly Arg Ser Gln Ile Pro Asp Glu Leu Leu Thr Trp Pro Glu Glu Val 115 120 125 Ala Ala Gly Ala Leu Glu Arg Leu Phe Met Gln Thr Gly Val Ser Trp 130 135 140 Ser Asp Pro Leu Arg Ala Gln Tyr Phe Ser Val Gln Phe Ser Glu Gly 145 150 155 160 Ile Arg Arg Ala Tyr Arg His Thr Leu Ala Thr Ser Pro Tyr Ser Ser 165 170 175 Tyr Arg Asn Pro Val Arg Arg Gln Arg Phe Phe * 180 185 <210> 312 <211> 217 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38124..38774) <400> 312 Met Thr Thr Ile Thr Glu Ile Ile Gly Arg Val Asn Thr Gln Leu Val 1 5 10 15 Asp Pro Met Met Val Arg Trp Pro Leu Gln Glu Leu Cys Asp Tyr Tyr 20 25 30 Asn Asp Ala Val Arg Ala Val Ile Leu Ala Arg Pro Asp Ala Gly Ala 35 40 45 Ser Leu Glu Thr Ile Ser Cys Val Pro Gly Ala Arg Gln Val Leu Pro 50 55 60 Asp Gly Val Ile Gln Leu Leu Asp Val Ile Cys Leu Ser Asp Gly Ser 65 70 75 80 Ala Val Arg Pro Leu Ser Arg Glu Val Leu Asp Ala Gln Tyr Pro Glu 85 90 95 Trp Pro Thr Met Lys Gly Ile Pro Glu Cys Phe Ile Ser Asn Asp Leu 100 105 110 Ser Pro Arg Val Phe Trp Leu Phe Pro Ala Pro Asp Lys Glu Ile Ser 115 120 125 Ile Asp Ala Val Val Ser Arg Ile Pro Glu Ala Val Tyr Val Leu Thr 130 135 140 Gln Asp Asp Asp Thr Pro Val Pro Leu Glu Glu Ala Tyr Val Asn Pro 145 150 155 160 Leu Val Glu Trp Met Leu Phe Arg Ala Phe Ser Lys Asp Ala Ala Gly 165 170 175 Gly Ala Glu Ser Gly Leu Ala Ala Gln His Tyr Gln Ser Phe Val Glu 180 185 190 Gln Leu Gly Ile Lys Gln Gly Ala Asp Ser Ala Leu Tyr Ala Arg Lys 195 200 205 Lys Val Phe Asn Gly Gly Gly Val * 210 215 <210> 313 <211> 646 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38771..40708) <400> 313 Val Ser Val Val Val Ser Gly Thr Leu Lys Ser Pro Asp Gly Glu Ala 1 5 10 15 Ile Ser Gly Ala Asn Ile Thr Leu Thr Ala Leu Thr Val Ser Pro Asp 20 25 30 Ala Leu Ser Gly Thr Ser Ala Ser Ala Val Thr Arg Glu Gly Gly Tyr 35 40 45 Tyr Gly Met Thr Met Asp Pro Gly Glu Tyr Ala Val Ser Val Thr Val 50 55 60 Lys Gly Lys Thr Ala Val Tyr Gly Arg Val Arg Ile Glu Gly Thr Glu 65 70 75 80 Ser Thr Val Thr Leu Asn Met Leu Leu Arg Arg Ser Leu Val Glu Val 85 90 95 Ser Ile Pro Gly Glu Leu Leu Thr Asp Phe Arg Gln Ile Gln Asn Asn 100 105 110 Val Ala Asp Asp Leu Ala Thr Ile Arg Arg Leu Asn Glu Asp Thr Ala 115 120 125 Thr Lys Asn Thr Gln Ala Thr Gln Ser Lys Glu Ser Ala Ala Ala Ser 130 135 140 Ala Lys Ser Ala Ser Asp Ser Ala Lys Thr Ala Thr Ser Arg Ala Ala 145 150 155 160 Glu Ala Gly Gln Lys Ala Thr Asp Ala Thr Glu Ala Ala Thr Arg Ala 165 170 175 Val Thr Ala Ala Gly Asn Ala Glu Glu Ser Ser Thr Arg Ala Gly Glu 180 185 190 Ser Glu Lys Ala Ala Gly Ala Asp Ala Glu Lys Ala Arg Gln His Ala 195 200 205 Glu Lys Ala Arg Leu Ala Gln Glu Ser Ala Gly Glu Ile Leu Lys Arg 210 215 220 Ala Glu Ala Ala Thr Val Ser Ala Glu Glu Ala Arg Arg Met Ala Glu 225 230 235 240 Asn Ala Arg Gly Pro Arg Gly Pro Gln Gly Glu Thr Gly Pro Lys Gly 245 250 255 Asp Val Gly Pro Lys Gly Glu Thr Gly Pro Val Gly Pro Gln Gly Pro 260 265 270 Ala Gly Pro Lys Gly Glu Arg Gly Asp Val Gly Ala Gln Gly Ala Val 275 280 285 Gly Pro Ala Gly Pro Arg Gly Glu Lys Gly Glu Gln Gly Glu Arg Gly 290 295 300 Pro Gln Gly Ile Pro Gly Leu Lys Gly Asp Thr Gly Glu Arg Gly Pro 305 310 315 320 Lys Gly Asp Gln Gly Asp Met Gly Pro Lys Gly Glu Lys Gly Asp Pro 325 330 335 Gly Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Glu Arg Gly Glu Ala 340 345 350 Gly Pro Gln Gly Pro Met Gly Ala Arg Gly Glu Arg Gly Glu Thr Gly 355 360 365 Pro Arg Gly Glu Pro Gly Pro Ala Gly Pro Arg Gly Glu Arg Gly Glu 370 375 380 Thr Gly Pro Gln Gly Pro Arg Gly Glu Pro Gly Pro Ala Gly Ser Ala 385 390 395 400 Ala Asn Val Ala Asp Ala Thr Thr Ala Gln Lys Gly Ile Val Gln Leu 405 410 415 Ser Ser Ala Thr Asp Ser Asp Asp Glu Thr Lys Ala Ala Thr Pro Lys 420 425 430 Ala Val Lys Ala Ala Met Asp Val Ala Asn Glu Ala Lys Thr Lys Ala 435 440 445 Glu Glu Ala Ala Ala Gly Gly Gly Val Pro Gly Pro Lys Gly Asp Lys 450 455 460 Gly Asp Thr Gly Pro Ala Gly Pro Ala Gly Pro Lys Gly Asp Lys Gly 465 470 475 480 Glu Arg Gly Asp Thr Gly Pro Val Gly Ala Thr Gly Glu Arg Gly Pro 485 490 495 Ala Gly Asp Ala Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp Arg 500 505 510 Gly Glu Arg Gly Glu Thr Gly Leu Thr Gly Asn Ala Gly Pro Gln Gly 515 520 525 Pro Lys Gly Asp Thr Gly Ala Ala Gly Pro Ala Gly Pro Gln Gly Pro 530 535 540 Lys Gly Glu Thr Gly Ala Ala Gly Pro Val Gly Ala Thr Gly Pro Gln 545 550 555 560 Gly Pro Lys Gly Asp Pro Gly Glu Thr Gln Ile Arg Phe Arg Leu Gly 565 570 575 Pro Gly Asn Ile Ile Glu Thr Asn Ser His Gly Trp Phe Pro Asp Thr 580 585 590 Asp Gly Ala Leu Ile Thr Gly Leu Thr Phe Leu Asp Pro Lys Asp Ala 595 600 605 Thr Arg Val Gln Gly Phe Phe Gln His Leu Gln Val Arg Phe Gly Asp 610 615 620 Gly Pro Trp Gln Asp Val Lys Gly Leu Asp Glu Val Gly Ser Asp Thr 625 630 635 640 Gly Arg Thr Gly Glu * 645 <210> 314 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40710..40979) <400> 314 Met Asn Ile Leu Arg Lys Leu Met Gln Ser Leu Cys Gly Cys Gly Lys 1 5 10 15 His Asp Asp Cys Glu Asn Gly Gln Ser Leu Thr Ala Gln Leu Arg Leu 20 25 30 Gly Pro Ala Asp Ile Leu Glu Ser Asp Glu Asn Gly Ile Ile Pro Glu 35 40 45 Gln Asp Arg Val Ile Thr Gln Val Val Ile Leu Asp Ala Asp Lys Lys 50 55 60 Gln Ile Gln Cys Val Val Arg Pro Leu Gln Ile Leu Arg Ala Asp Gly 65 70 75 80 Thr Trp Glu Asn Ile Gly Gly Met Lys * 85 <210> 315 <211> 81 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41065..41307) <400> 315 Met Leu Ile Arg Trp Ser Glu Gly Cys Arg Val Ile Leu Val Gln Glu 1 5 10 15 Phe Phe Met Pro Glu Asn Arg Arg Ile Ile Leu Asp Ser Lys Glu Ser 20 25 30 Trp Leu Ile Ile Cys Asp Ser Gln Leu Gly His Leu Met Arg Ser Met 35 40 45 Tyr Gln Gly Arg Arg Phe Ile Gln Leu Asn Leu Glu Lys Leu Lys Gly 50 55 60 Val His Asp Val Ala Leu Pro Val Lys Trp Glu Phe Thr Arg Arg Gln 65 70 75 80 * <210> 316 <211> 81 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41194..41436) <400> 316 Leu Leu Pro Phe Phe His Cys Ile Ile Ile Ala Ala Val Ala Thr Arg 1 5 10 15 Ser Ile Thr Pro His Thr Gln Asp Val Ser His Ser His His Thr Val 20 25 30 His Phe Ser Pro Phe Pro Tyr Thr Glu Ser Tyr Ser Leu Ser Ser Cys 35 40 45 Glu Phe Pro Phe His Trp Gln Gly Asp Ile Met Tyr Pro Phe Gln Phe 50 55 60 Phe Gln Ile Gln Leu Asn Lys Thr Ala Ser Leu Ile His Thr Ala His 65 70 75 80 * <210> 317 <211> 568 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41524..43227) <400> 317 Val Met Pro Ile Ala Ile Leu Ala Asn Ser Ile Ile Asn Pro Leu Ile 1 5 10 15 Phe Lys Pro Glu Ala Val Lys Gly Ile Ser Met Pro Tyr Ile Asp Ile 20 25 30 Thr Thr Met Arg Gly Met Met Pro Arg Val Val Thr Ser Met Leu Pro 35 40 45 Glu His Ser Ala Val Leu Ala Glu Asp Cys His Phe Arg Phe Gly Val 50 55 60 Ile Thr Pro Glu Arg Gln Ile Ser Gly Val Glu Lys Thr Phe Thr Ile 65 70 75 80 Lys Pro Lys Thr Ile Phe His Tyr Arg Asp Asp Phe Trp Phe Ala Trp 85 90 95 Pro Asp Val Val Asp Val Ile Arg Ser Pro Ile Ala Gln Asp Pro His 100 105 110 Gly Arg Ile Tyr Tyr Thr Asp Gly Arg Phe Pro Lys Val Thr Asp Ala 115 120 125 Thr Ile Ala Thr Lys Gly Asp Gly Asn His Pro Thr Ser Ser Tyr Arg 130 135 140 Leu Gly Ile Pro Ala Pro Thr Thr Ala Pro Val Cys Thr Val Gln Gln 145 150 155 160 Gly Gly Asp Val Ser Asp Asp Asn Pro Asn Asp Asp Glu Thr Arg Phe 165 170 175 Tyr Thr Glu Thr Phe Val Ser Asp Tyr Gly Glu Glu Gly Pro Pro Gly 180 185 190 Pro Ala Ser Leu Glu Val Thr Leu Arg Thr Pro Gly Thr Ala Val Gln 195 200 205 Leu Thr Leu Ala Pro Val Pro Leu Gln Asn Ala Ser Ile Lys Arg Arg 210 215 220 Arg Ile Tyr Arg Ser Ala Ser Gly Gly Gly Glu Ala Asp Phe Leu Leu 225 230 235 240 Val Ala Glu Leu Asp Ala Ser Val Leu Ser Tyr Thr Asp Lys Ile Pro 245 250 255 Ala Lys Asn Leu Gly Pro Ser Leu Ala Thr Trp Asp Tyr Leu Pro Pro 260 265 270 Pro Glu Asn Met Thr Gly Leu Cys Leu Met Ala Asn Gly Ile Ala Ala 275 280 285 Gly Phe Ala Gly Asn Glu Val Met Phe Ser Glu Ala Tyr Leu Pro Tyr 290 295 300 Ala Trp Pro Glu Val Asn Arg His Thr Thr Ala Glu Asp Ile Val Ala 305 310 315 320 Ile Cys Pro Leu Gly Thr Ser Leu Val Val Ala Thr Lys Gly Glu Pro 325 330 335 Tyr Leu Phe Ser Gly Val Ser Pro Ser Thr Ile Ser Gly Ser Lys Ile 340 345 350 Pro Ser Met Gln Ala Cys Leu Ser Arg Arg Ser Met Val Ala Met Glu 355 360 365 Gly Phe Val Leu Tyr Ala Gly Thr Asn Gly Leu Val Ser Val Asp Ala 370 375 380 Asn Gly Asn Val Ala Leu Ala Thr Glu Gln Ile Val Ser Pro Glu Gln 385 390 395 400 Trp Gln Ser Gln Phe Asn Pro Ala Ser Ile Val Ala Tyr Pro Trp Arg 405 410 415 Gly Glu Tyr Ile Ala Cys Tyr Thr Lys Pro Asp Gly Lys Gln Asp Val 420 425 430 Phe Val Phe Ser Pro Val Asn Met Asp Ile Arg Tyr Leu Ser Thr Pro 435 440 445 Phe Asp Cys Ala Trp Val Asp Leu Ala Lys Asp Met Met Arg Val Val 450 455 460 Thr Gly Asp Lys Met Ser Val Leu Ala Gly Gly Ala Leu Pro Ser Thr 465 470 475 480 Ile Arg Trp His Ser Lys Ile Phe Ser Leu Pro Glu Arg Thr Ser Phe 485 490 495 Ser Cys Ile Arg Val Lys Ser Pro Ala Pro Glu Arg Val Gly Ile Thr 500 505 510 Ile Met Ala Asp Asp Val Pro Val Ile His Phe Ala Pro Gly Thr Phe 515 520 525 Lys Gly Ser Val Val Arg Leu Pro Ala Ala Thr Gly Gln Asn Trp Gln 530 535 540 Val Met Val Ser Gly Phe Gly Gln Val Glu Arg Ile Thr Leu Ser Thr 545 550 555 560 Ser Met Ser Glu Met Pro Val * 565 <210> 318 <211> 423 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43224..44492) <400> 318 Met Thr Arg Lys Pro Trp Arg Ala Gly Lys Asp Leu Ser Thr Val Val 1 5 10 15 Glu Asn Met Glu Ile Gly Thr Gly Gln Arg Gly Asp Gly Arg His Ala 20 25 30 Phe Val Thr Arg Glu Glu Leu Val Gly Leu Lys Leu Ala Arg Arg Arg 35 40 45 Thr Ser Gly Gly Ala Ser Tyr Ala Leu Asn Pro Gly Ile Glu Ile Asp 50 55 60 Ser Thr Leu Met Thr Val Asp Phe Pro Thr Lys Pro Leu Asn Phe Lys 65 70 75 80 Ala Thr Gly Gly Phe Gly Ser Val Leu Leu Glu Trp Asp Met Pro Asn 85 90 95 Tyr Arg Gly His Ser Leu Thr Glu Ile Trp Arg Gly Thr Glu Asp Asp 100 105 110 Leu Ala Asp Ala Val Leu Val Ala Thr Thr Pro Gly Gln Val Tyr Gly 115 120 125 Asp Pro Val Asp Pro Gly Trp Ser Gly Phe Tyr Trp Ile Arg Phe Val 130 135 140 Asn Ala Ala Gly Val Lys Gly Pro Trp Asn Ala Glu Lys Gly Thr Gln 145 150 155 160 Ala Gln Thr Gln Ile Gly Val Lys Ala Ile Ile Asp Gln Ile Arg Asp 165 170 175 Glu Ala Ala Lys Ser Pro Val Val Ser Glu Leu Arg Lys Glu Ile Lys 180 185 190 Asn Ala Gln Gly Gln Ala Val Lys Asp Ala Ala Ile Lys Thr Thr Glu 195 200 205 Val Val Gly Thr Leu Arg Glu Glu Thr Thr Arg Thr Ile Gly Gly Ile 210 215 220 Glu Thr Arg Ile Ser Thr Leu Asp Ser Ser Thr Ser Glu Ser Leu Asn 225 230 235 240 Glu Val Asp Lys Arg Ile Thr Lys Leu Asp Lys Glu Gly Gly Glu Ala 245 250 255 Phe Leu Ala Met Trp Ser Lys Lys Ala Gly Val Asp Gly Ile Thr Ala 260 265 270 Gly Ile Gly Ile Val Ala Gly Lys Asp Ser Glu Gly Arg Pro Val Ser 275 280 285 Gln Val Ala Ile Ser Ala Ser Gln Leu Phe Val Phe Asp Pro Asn Asn 290 295 300 Pro Asp Asn Thr Ala Tyr Pro Phe Ala Val Ser Gly Gly Lys Val Val 305 310 315 320 Ile Pro Lys Ala Met Ile Tyr Asp Ala Val Ile Glu Thr Leu Val Ser 325 330 335 Arg Lys Val Val Ala Asp Glu Val Lys Ala Gly Val Ser Ile Thr Ser 340 345 350 Pro Val Ile Arg Ser Ala Val Ile Gln Asn Gly Asn Phe Gln Val Asp 355 360 365 Ser Gln Gly Asn Leu Asn Ile Gly Gly Leu Phe Ser Val Thr Ser Gln 370 375 380 Gly Gln Leu Thr Ile Arg Tyr Ser Asn Gln Asn Val Gly Leu Val Ile 385 390 395 400 Arg Asn Asp Lys Ile Glu Val Tyr Asp Gln Asn Gly Arg Leu Ala Val 405 410 415 Arg Ile Gly Arg Leu Arg * 420 <210> 319 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44507..44785) <400> 319 Leu Glu Tyr Gly Phe Ala Ile Tyr Asn Arg Asn Asn Val Asn Val Thr 1 5 10 15 Gly Val Leu Thr Pro Val Phe Phe Leu Asp Arg Phe Thr Ala Glu Ser 20 25 30 Gly Ser Lys Thr Tyr Thr Asn Lys Pro Asp Gly Lys Ser Leu Gln Ala 35 40 45 Val Cys Cys Leu Phe Pro Trp Asn Asn Val Phe Ala Asp Arg Lys Val 50 55 60 Pro Lys Ile Thr Ile Asn Asp Asn Thr Val Thr Trp Ser Asn Leu Glu 65 70 75 80 Gln Gly Met Gly Ser Tyr Ile Tyr Thr Phe Trp Gly * 85 90 <210> 320 <211> 206 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44791..45408) <400> 320 Met Tyr Gly Leu Ser Ile Met Lys Pro Asp Gly Ser Val Trp Ile Ser 1 5 10 15 Pro Gly Phe Thr Pro Gln Cys Leu Ile Asn Lys Gly Thr Ile Pro Ala 20 25 30 Thr Glu Lys Ser Phe Phe Lys Thr Ser Ile Pro Ser Gly Lys Ser Cys 35 40 45 Phe Phe Phe Ile Arg Thr Glu Lys Lys Ala Asp Val Met Tyr Thr His 50 55 60 Glu Gln Ile Asp Gly Tyr His Ala Leu Arg Leu His Val Ile Val Arg 65 70 75 80 Gly Thr Asn Pro Gly Val Thr Thr Val Tyr Ala Phe Ala Asn Met Val 85 90 95 Thr Pro Pro Ser Glu Tyr Gly Ile Ala Met Tyr Asn Pro Asp Gly Glu 100 105 110 Met Ile Tyr His Gly Glu Met Met Leu Leu Asp Ala Lys Leu Ile Pro 115 120 125 Val Asp Ile Lys Phe Glu Lys Asp Leu Gly Tyr Pro Cys Ala Ile Met 130 135 140 Pro Ala Leu Val Gly Tyr Tyr Asn Trp Lys Arg Thr Pro Tyr Asp Arg 145 150 155 160 Pro Ile Tyr Thr Thr Ser Thr Gly Ala Thr Gly Asn Lys Ile Tyr Ser 165 170 175 Cys Glu His Tyr Ser Gly Gly Ala Thr Trp Asp Ile Arg Lys Pro Tyr 180 185 190 Ile Asp Lys Val Leu Val Ile Asn Thr Ser Val Tyr Asp * 195 200 205 <210> 321 <211> 245 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45499..46233) <400> 321 Met Lys Ser Ile Ala Thr Leu Val Val Cys Ala Ile Ser Gly Ile Ala 1 5 10 15 Cys Val Asn Leu Ser Ala His Ala Ala Glu Gly Glu His Thr Ile Ser 20 25 30 Leu Gly Tyr Ala His Phe Gln Phe Pro Gly Leu Lys Asp Phe Val Lys 35 40 45 Asp Ala Thr Ala His Asn Arg Glu Thr Phe Ser His Phe Val Asn Arg 50 55 60 Asn Tyr Phe Ser Ser Leu Gly Glu Tyr Thr Asp Gly Arg Val Ser Gly 65 70 75 80 Tyr Glu Gly Lys Asp Lys Asn Pro Gln Gly Ile Asn Ile Arg Tyr Arg 85 90 95 Tyr Glu Ile Thr Asp Asp Phe Gly Val Ile Thr Ser Phe Thr Trp Thr 100 105 110 Arg Ser Leu Thr Asn Ser Gln Thr Phe Ile Asp Val Gln Ser Ala Asp 115 120 125 His Thr Arg Lys Ile Lys Asn Pro Ala Ala Ser Ala Arg Thr Asp Ile 130 135 140 Arg Ala Asn Tyr Trp Ser Leu Leu Ala Gly Pro Ser Trp Arg Val Asn 145 150 155 160 Gln Tyr Met Ser Leu Tyr Ala Met Ala Gly Met Gly Val Ala Lys Val 165 170 175 Ser Ala Asp Leu Lys Ile Lys Asp Asn Ile Asn Ser Ser Gly Gly Phe 180 185 190 Ser Glu Ser Asn Ser Thr Lys Lys Thr Ser Leu Ala Trp Ala Ala Gly 195 200 205 Ala Gln Phe Asn Leu Asn Glu Ser Val Thr Leu Asp Val Ala Tyr Glu 210 215 220 Gly Ser Gly Ser Gly Asp Trp Arg Thr Ser Gly Val Thr Ala Gly Ile 225 230 235 240 Gly Leu Lys Phe * <210> 322 <211> 134 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46663..47064) <400> 322 Met Ala Pro Val Ser Gly Glu Arg Met Asn Asp Lys Ile Leu Trp Tyr 1 5 10 15 Met Gln Arg Val Val Arg Asn Ser Arg Asn Pro Glu Phe Met Asn Glu 20 25 30 Val Lys Asp Ala Cys Leu Lys Lys Gln Ala Phe Cys Phe Glu Ala Pro 35 40 45 Asp Gly Phe Leu Val Leu Arg Ser Val Leu Ser Ala Asp Gly Ile Pro 50 55 60 Tyr Val Leu Val Leu Leu Gly Val Cys Thr Gly Ser Asn Ser Val Glu 65 70 75 80 Arg Tyr Leu Pro Glu Val Lys Thr Leu Thr His Leu Ala Gly Gly Arg 85 90 95 Trp Ala Glu Phe His Thr Ala Arg Arg Gly Phe Ile Arg Leu Gly Lys 100 105 110 Arg Leu Gly Phe Glu Arg Met Pro Asp Asp Glu Asp Gly Phe Met Val 115 120 125 Phe Arg Ile Ala Val * 130 <210> 323 <211> 219 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(47158..47814) <400> 323 Met Gly Gly Ser Lys Gly Gly Gly Asp Thr Lys Val Lys Pro Thr Ala 1 5 10 15 Ala Gln Ile Ala Gln Glu Glu Val Ala Trp Lys Gly Trp Gln Asp Tyr 20 25 30 Lys Asn Ile Leu Arg Pro Ala Glu Asp Asn Phe Met Glu Lys Val Asp 35 40 45 Asp Leu Asn Ser Glu Gln Gln Tyr Asp Asn Ile Ala Gly Thr Thr Asn 50 55 60 Leu Gly Tyr Gln Lys Gln Phe Gly Glu Ala Arg Lys Glu Leu Ala Gly 65 70 75 80 Asn Leu Ala Gln Ser Gly Val Asp Pro Ser Ser Gly Arg Phe Asn Ala 85 90 95 Val Met Asn Ala Asn Gln Ser Asp Gln Val Thr Gly Gln Ile Asp Thr 100 105 110 Thr Thr Arg Gly Gln Val Ser Gln Ala Asp Lys Tyr Val Ala Gly Leu 115 120 125 Gln Asp Val Ala Ala Leu Gly Ser Gly Gln Lys Ala Asp Ala Leu Gln 130 135 140 Ser Phe Asn Ser Leu Ala Asp Ser Ser Leu Ala Lys Ala Lys Ser Asp 145 150 155 160 Ala Gln Ala Ala Phe Thr Lys Gln Gln Gly Arg Ala Ser Leu Val Gly 165 170 175 Ala Gly Leu Gly Ala Ala Gly Ala Tyr Ala Met His Lys Ala Gly Gly 180 185 190 Ser Gly Gly Ser Gly Gly Ala Lys Thr Pro Gly Thr Gly Ala Asn Ala 195 200 205 Ile Gln His Gln Ala Gln Asn Trp Arg Leu * 210 215 <210> 324 <211> 149 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(47817..48263) <400> 324 Met Glu Tyr Gly Lys Tyr Glu Thr Leu Ala Arg Ala Gly Tyr Ser Gly 1 5 10 15 Ala Asp Arg Pro Gln Gly Asp Trp Gln Thr Ser Ala Ala Leu Thr Arg 20 25 30 Gln Gln Tyr Asp Asp Trp Arg Thr Arg Tyr Leu Pro Arg Val Ala Arg 35 40 45 Leu Ala Asp Leu Gly Glu Asn Asn Ser Leu Met Asn Ala Gln Leu Ala 50 55 60 Arg Val Gly Gly Leu Ala Thr Ser Ser Leu Arg Thr Ala Gln Met Ala 65 70 75 80 Gln Asp Asn Gln Met Ala Arg Tyr Gly Val Asn Arg Pro Asp Asn Pro 85 90 95 Asp Ser Asn Thr Leu Gly Leu Arg Asn Ala Leu Ala Ile Ala Gly Ala 100 105 110 Lys Asn Gly Ile Arg Glu Ala Glu Gln Asp Arg Gln Met Asn Ile Leu 115 120 125 Thr Gly Ala Ser Ala Pro Ala Arg Gln Lys Leu Ser Val Gly Gly Gln 130 135 140 Leu Val Ala Ala * 145 <210> 325 <211> 84 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48273..48524) <400> 325 Met Gly Tyr Gly Leu Leu Asp Ile Ala Asn Gln Ser Arg Arg Glu Ala 1 5 10 15 Leu Gln Gly Ile Ser Asp Ala Asp Arg Arg Arg Glu Glu Ile Glu Ala 20 25 30 Ala Asn Lys Gln Met Ala Ala Gln Gln Lys Ala Gln Asn Lys Gln Asn 35 40 45 Ile Gly Thr Gly Ile Gly Thr Gly Ala Ala Ile Gly Ala Ser Val Gly 50 55 60 Gly Pro Val Gly Ala Val Ala Gly Ala Val Ile Gly Gly Ile Ala Gly 65 70 75 80 Ser Leu Phe * <210> 326 <211> 422 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48535..49800) <400> 326 Met Ser Gly Phe Ala Gln Gly Leu Leu Ala Gly Phe Ser Thr Val Asp 1 5 10 15 Gln Ala Met Thr Arg Arg Lys Glu Leu Gly Leu Arg Glu Ala Gln Leu 20 25 30 Ala Arg Gln Gln Lys Asn Asn Glu Arg Asp Phe Glu Phe Ala Gln Ser 35 40 45 Gln Phe Glu His Asn Lys Asn Val Asp Gln Arg Asn Phe Asp Tyr Arg 50 55 60 Ala Lys Val Asp Asp Arg Asn Tyr Ala Leu Lys Glu Arg Glu Phe Asn 65 70 75 80 Ala Asn Gln Asn Tyr Arg Asn Ala Ser Leu Gly Met Glu Gln Gln Arg 85 90 95 Leu Gln Leu Gln Lys Tyr Asn Gln Arg Arg Leu Glu Tyr Asn Asp Met 100 105 110 Ile Ala His Ser Gln Pro Leu Met Glu Ala Leu Gly Lys Ala Ile Glu 115 120 125 Ala Gly Asp Gln Glu Ala Ala Thr Arg Leu Phe Gly Gln Leu Pro Lys 130 135 140 Gly His Pro Leu Ile Leu Met Ser Asn Glu Gly Tyr Ala Ala Lys Ala 145 150 155 160 Gly Gln Ala Val Ile Asn Leu Gln Lys Ile Phe Gly Asp Lys Pro Asp 165 170 175 Met Ala Ile Asp Ser Leu Asn Thr Pro Glu Asn Leu Asp Val Leu Ser 180 185 190 Gly Val Phe Ala Pro Glu Leu Gln Gln Arg Ile Gly Met Pro Asp Ser 195 200 205 Thr Gly Asp Lys Thr Ile Lys Glu Ala Arg Ile Gly Ser Ile Val Pro 210 215 220 Ala Gln Gln Glu Gly Tyr Val Leu Ile Gly Leu Asp Leu Thr Tyr Ser 225 230 235 240 Asp Gly Ser Thr Ala His Lys Pro Val Thr Glu Tyr Gly Ser Ala His 245 250 255 Pro Asp Asp Gln Thr Val Leu Ala Ile Pro Val Asp Lys Ala Ile Ala 260 265 270 Gln Val Arg Asp Arg Ser Lys Phe Ala Glu Ile Ser Lys Asn Tyr Gly 275 280 285 Tyr Phe Met Pro Lys Gln Gln Gly Leu Ser Leu Lys Glu Leu Gln Lys 290 295 300 Gly Ala Ser Asn Val Ala Ala Asp Ala Ile Lys Asn Gly Gly Asn Ala 305 310 315 320 Gln Ala Ala Val Asp Glu Tyr Tyr Ala Ala Thr Gly Ser Gln Pro His 325 330 335 Gln Gln Lys Ile Gln Gln Gln Lys Leu Gln Gln Gln Val Ile Asn Trp 340 345 350 Ala Gly Asp Asp Pro Asp Lys Leu Ser Phe Ala Arg Asn Val Ala Ala 355 360 365 Arg Gln Pro Glu Met Leu Glu Pro Gln Asn Gln Lys Leu Leu Glu Asn 370 375 380 Gly Tyr Ala Asn Phe Leu Arg Ile Gln Lys Ala Arg Gly Glu Gln Ala 385 390 395 400 Arg Asp Glu Ser Ala Ser Ser Ala Ser Gln Phe Ile Arg Gly Leu Lys 405 410 415 Gln Asn Tyr Ala Gln * 420 <210> 327 <211> 2794 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(49870..58251) <400> 327 Met Ala Tyr Ser Glu Glu Gln Arg Pro Glu Ala Gln Leu Gly Asn Gln 1 5 10 15 Asn Arg Asn Ser Leu Asn Ile Gln Gln Pro Gly Glu Thr Asp Ser Tyr 20 25 30 Glu Ala Phe Phe Ser Asp Pro Asn Arg Trp Lys Asp Asn Ser Thr Ser 35 40 45 Phe Ser Leu Gly Asp Val Leu Pro Thr Met Gly Lys Gly Phe Ala Gln 50 55 60 Ser Val Arg Gly Thr Gly Glu Met Ala Arg Gly Leu Gly Asp Ala Met 65 70 75 80 Ile Gln Ser Pro Val Lys Thr Gly Ala Arg Ile Leu Asn Glu Phe Ser 85 90 95 Arg Met Gly Leu Pro Gly Val Ala Thr Val Gln Asp Ile Phe Ala Gly 100 105 110 Gly Ser Arg Gly Ala Asp Glu Val Ile Asp Thr Leu Pro Asp Gly Lys 115 120 125 Asn Ala Val Thr Asp Thr Val Gly Lys Gly Leu Lys Ala Thr Gly Lys 130 135 140 Ala Val Ser Asp Gly Ala Lys Ala Thr Asp Glu Trp Leu Thr Gly Lys 145 150 155 160 Met Ser Pro Gly Ala Val Arg Ala Leu Asn Thr Pro Met Thr Glu Gly 165 170 175 Tyr Asn Asp Ser Ala Val Trp Val Ala Lys Gly Val Asn Leu Ile Gly 180 185 190 Ala Leu Val Pro Asp Met Val Ala Gly Gly Val Ala Arg Lys Val Gly 195 200 205 Asp Val Thr Leu Arg Lys Met Leu Thr Ala Gly Leu Glu Lys Lys Tyr 210 215 220 Ile Ala Ala Gly Met Gln Pro Glu Arg Ala Thr Ala Leu Ala Ala Glu 225 230 235 240 Ala Val Asp Lys Lys Met Pro Asp Leu Phe Gln Ala Gly Leu Ile Thr 245 250 255 His Ser Thr Val Ser Ala Gln Gly Gln Ser Ala Met Ala Ala Ala Asp 260 265 270 Ala Val Leu Asn Ala Asp Tyr Ser Glu Leu Ala Gln Ser Pro Lys Phe 275 280 285 Gln Gln Thr Phe Leu Ser Ile Asp Ala Asp Pro Gln His Ala Gln Leu 290 295 300 Thr Asp Arg Gln Lys Met Asp Leu Ala Lys Glu Arg Val Ala Asp Glu 305 310 315 320 Val Arg Ala Gln Leu Ala Thr Asp Pro Glu Leu Leu Ala Val Asn Ala 325 330 335 Met Ala Ala Lys Leu Gly Asp Ala Gln Leu Phe Asn Leu Val Thr Arg 340 345 350 Gly Thr Ala Lys Thr Val Lys Ser Gly Ile Val Arg Asn Ala Thr Glu 355 360 365 Gln Gly Ala Ile Asn Ala Ala Gln Gly Gly Tyr Ser Arg Tyr Gln Glu 370 375 380 Asn Thr Ala Leu Arg Glu Thr Ala Gly Met Gly Val Ser Pro Trp Glu 385 390 395 400 Gly Val Ala Asp Ala Thr Ile Glu Gly Ala Ala Phe Gly Ala Ala Met 405 410 415 Gly Ala Pro Phe Gly Ala Val Ala Gly Tyr Arg Gly Arg Arg Gln Ala 420 425 430 Ala Glu Glu Thr Ala Met Arg Asp Ala Glu Thr Val Gln Gln Asp Asp 435 440 445 Ala Ala Pro Gln Pro Glu Ser Val Asp Pro Val Ala Gln Gln Arg Glu 450 455 460 Ser Met Gln Gly Met Asn Arg Glu Gln Leu Leu Glu Gln Tyr Ala Asp 465 470 475 480 Ala Asp Met Ala Thr Glu Gly Asp Ala Ser Ala Ala His Arg Arg Glu 485 490 495 Ala Ala Ser Gln Leu Leu Asn Glu Leu Asp Glu Gln Thr Lys Arg Gln 500 505 510 Ala Val Met Asn Glu Leu Lys Ala Lys Pro Arg Ser Glu Leu Leu Glu 515 520 525 Glu Tyr Arg Arg Leu Ser Gln Lys Glu Gly Arg Thr Glu Thr Glu Glu 530 535 540 Gln Gln Phe Gln Ala Ile Arg Glu Val Ile Arg Pro Gln Gln Glu Val 545 550 555 560 Thr Pro Glu Ala Gln Ser Gln Pro Glu Asn Ala Glu Asp Gly Asn Gly 565 570 575 Ser Ile Tyr Pro Thr Val Arg Phe Arg Asp Pro Asn Glu Val Arg Ile 580 585 590 Glu Ile Asn Gly Asn Gly Ala Ser Arg Pro Ala Glu Arg Ile Glu Lys 595 600 605 Val Arg Pro Asp Asn Arg Tyr Phe Thr Asp Glu Lys Ser Ala Met Gly 610 615 620 Ser Asp Val Phe Arg Asn Ala Ala Ala Thr Gly Leu Lys Pro Ser Val 625 630 635 640 Val Lys Lys Gly Glu Asn Gln Tyr Ala Val Glu Met Asp Asn Pro Ala 645 650 655 Phe Ser Glu Asp Val Ala Thr Glu Thr Ile Asn Thr Leu Ala Asp Gly 660 665 670 Glu Arg Ile Ala Asp Ala Asp Pro Met Glu Gln Pro Ala Phe Met Arg 675 680 685 Asp Pro Arg Phe Arg Gly Phe Thr Gly Asp Asp Thr Glu Val Gln Ala 690 695 700 Arg Leu Ala Arg Gly Asn Ala Pro Thr Ala Glu Glu Leu Val Arg Ser 705 710 715 720 Gln Met Ala Glu Gly Asp Ala Gly Pro Thr Ala Gln Glu Leu Thr Glu 725 730 735 Arg Pro Arg Leu Pro Ala Pro Gly Asp Ile His Pro Gly Gln Gly Tyr 740 745 750 Pro Leu Pro Gly Glu Val Ala Arg Thr Pro Asp Glu Asn Gln Ala Gly 755 760 765 Arg Gly Gly Arg Phe Thr Thr Thr Gly Glu Val Lys Gly Gln Ser Phe 770 775 780 Gln Lys Gly Gln Ala Pro Ala Pro Glu Asn Ala Ala Gly Arg Gln Gly 785 790 795 800 Glu Thr Leu Glu Gly Asp Met Val Arg Arg Gly Leu Pro Ser Pro Asp 805 810 815 Ala Gln Asn Ala Thr Ala Pro Val Arg Glu Gly Leu Pro Ala Pro Asp 820 825 830 Ile Ala Arg Asn Val Arg Met Pro Gln Pro Glu Ser Leu Pro Arg Thr 835 840 845 Val Arg Asp Ser Leu Pro Glu Leu Ala Gln Gln Ala Glu Val Arg Arg 850 855 860 Gln Ala Gly Gly Asn Arg Asp Ile Pro Gln Pro Glu Thr Ile Ala Pro 865 870 875 880 Glu Ser Glu Thr Thr Val Ser Thr Asp Arg Glu Ala Thr Val Arg Gly 885 890 895 Gly Glu Val Arg Gly Lys Lys Ile Glu Asp Phe Gly Glu Glu Ile Lys 900 905 910 Gly Ala Ala Lys His Arg Tyr Ala Gln Leu Ala Glu Thr Leu Gly Lys 915 920 925 Thr Leu Glu Asp Arg Asp Tyr Ala Thr Gln Pro Leu Ser Lys Leu Phe 930 935 940 Pro Lys Pro Asp Tyr Ala Lys Leu Ala Asn Glu Gly Ala Asp Ala Asp 945 950 955 960 Thr Leu Ala Met Ile Ala Leu Tyr Arg Ser Asp Ile Pro Ala Lys Thr 965 970 975 Lys His Asn Thr Ala Gly Trp Gly Glu Ser Ile Lys Lys Val Arg His 980 985 990 Ser Val Ser Glu Met Leu Asn Gly Thr Val Ser Ala Lys Arg Leu Ala 995 1000 1005 Glu Trp Met Glu Gly Arg Met Pro Ser Arg Tyr Ala Asp Thr Trp Gln 1010 1015 1020 Leu Leu Arg Thr Leu Pro Pro Ser Gln Met Asp Arg Ala Ser Ala Tyr 1025 1030 1035 1040 Arg Val Val Ser Gly Val Tyr Gln Ala Ala Gly Gly Lys Arg Tyr Asp 1045 1050 1055 Pro Pro Gln Lys Leu Tyr Ser Leu Arg Asn Lys Asp Asn Lys Gly Ser 1060 1065 1070 Asn Leu Phe Phe Ser Glu Ser Arg Asp Glu Leu Leu Ala Lys Ala Lys 1075 1080 1085 Val Trp Phe Ala Glu Gln Glu Glu Lys Ser Gln Ala Lys Gly Asp Glu 1090 1095 1100 Lys Thr Ala Pro Ser Pro Asp Asp Lys Ile Arg Phe Asp Val Tyr Arg 1105 1110 1115 1120 Asn Thr Arg Ser Gly Asp Ile Phe Ile Ala Tyr Gly Lys Asn Lys Met 1125 1130 1135 Arg Val Arg Gly Gly Phe Lys Ser Ala Ser Asp Ala Arg Lys Tyr Ile 1140 1145 1150 Asp Ser His Arg Asp Glu Leu Val Arg His Val Lys Glu Met Arg Glu 1155 1160 1165 Ile Ser Arg Glu Glu Gln Arg Asn Ala Thr Asn Arg Asp Arg Thr Gly 1170 1175 1180 Pro Glu Arg Arg Lys Gly Asn Val Ser Pro Glu Gln Phe Ser Asp Ala 1185 1190 1195 1200 Phe Gly Phe Arg Gly Val Gln Phe Gly Asn Tyr Val Glu Gly Pro Arg 1205 1210 1215 Arg Gln Ala Asp Leu Asn Arg Ala Tyr Asp Ser Leu His Asp Leu Ala 1220 1225 1230 Glu Val Leu Asn Val Pro Thr Lys Ala Leu Ser Leu Asn Gly Arg Leu 1235 1240 1245 Gly Leu Ala Phe Gly Ala Arg Gly Lys Gly Lys Ala Ala Ala His Tyr 1250 1255 1260 Glu Ser Gly Glu Val Ala Ile Asn Leu Thr Lys Gly Asn Gly Pro Gly 1265 1270 1275 1280 Ala Leu Ala His Glu Trp Phe His Ser Leu Asp Asn Tyr Phe Gly Arg 1285 1290 1295 Tyr Asp Val Ser Asn Asp Gly Lys Ile Thr Ser Gly Gly Asp Phe Met 1300 1305 1310 Thr Glu Ala Gln Arg Val Arg Arg Ile Phe Lys Asp Gly Arg Tyr Val 1315 1320 1325 Asp Ala Glu Tyr Pro Val Arg Gln Glu Val Tyr Asp Ala Phe Lys Gly 1330 1335 1340 Val Ile Gln Ala Ile Lys Asn Ser Asp Met Pro Arg Arg Ser Ala Leu 1345 1350 1355 1360 Leu Asp Glu Val Arg Ser Lys Pro Tyr Trp Ser Thr Asp Val Glu Met 1365 1370 1375 Ala Ala Arg Ala Phe Glu Arg Tyr Val Gln Asp Lys Ala Arg Met Ala 1380 1385 1390 Gly Val Glu Asn Asp Tyr Leu Val Asn Ile Arg Lys Ala Pro Glu His 1395 1400 1405 Asn Thr Asp Asn Thr Tyr Ala Tyr Pro Thr Asn Ala Glu Leu Asp Gly 1410 1415 1420 Gly Ile Arg Glu Ala Phe Asp His Leu Phe Arg Thr Leu Lys Thr Arg 1425 1430 1435 1440 Glu Thr Asp Lys Gly Val Ala Phe Tyr Ser Arg Lys Gly Val Thr Arg 1445 1450 1455 Thr Pro Glu Gly Asn Leu Ile Ser Asp Val Asn Arg Ser Ala Glu Ala 1460 1465 1470 Lys Gly Ser Pro Val Pro Gln Val Glu Ala Val Ala Arg Gly Val Met 1475 1480 1485 Ser Gly Ile Lys Asp Ser Asp Leu Lys Val Arg Val Val Lys Ser Gln 1490 1495 1500 Lys Glu Ala Glu Ala Leu Ala Gly Glu Leu Phe Asp Gly Tyr Gly Arg 1505 1510 1515 1520 Val His Ala Phe Tyr Arg Pro Asp Lys Arg Glu Ile Val Leu Val Ala 1525 1530 1535 Asp Asn Ile Pro Asp Gly Arg Thr Val Arg Glu Lys Leu Arg His Glu 1540 1545 1550 Ile Ile His His Ala Met Glu His Val Val Thr Pro Ala Glu Tyr Gln 1555 1560 1565 Thr Ile Ile Lys Thr Val Leu Lys Thr Arg Asp Ser Asp Asn Val Thr 1570 1575 1580 Ile Arg Glu Ala Trp Arg Lys Val Asp Ala Ser Tyr Gly Lys Glu Ser 1585 1590 1595 1600 Pro Glu Val Gln Ala Gly Glu Phe Leu Ala His Met Ala Glu Lys Gln 1605 1610 1615 Pro Asn Lys Phe Val Ala Ala Trp Glu Arg Val Val Ala Leu Val Lys 1620 1625 1630 Gly Val Leu Arg Arg Thr Gly Leu Leu Lys Pro Thr Glu Leu Asn Asp 1635 1640 1645 Ile Arg Leu Val Arg Glu Thr Ile Arg Thr Leu Gly Gln Arg Val Arg 1650 1655 1660 Glu Gly Tyr Thr Pro Arg Glu Asp Gly Ala Gly Ala Ser Phe Gln Tyr 1665 1670 1675 1680 Ser Arg Ser Gly Lys Arg Asp Pro Phe Lys Val Pro Glu Gly Glu Gly 1685 1690 1695 Glu Arg Tyr Arg Asp Asp Leu Ala Arg Met Met Lys Ser Leu Arg Thr 1700 1705 1710 Thr Asp Leu Thr Val Asn Ile Gly Arg Thr Pro Pro Val Leu Arg His 1715 1720 1725 Leu Gly Ala Pro Asp Leu Pro Leu Val Ile Ser Arg Asp Thr Val Arg 1730 1735 1740 Lys Ala Thr Asn Gly Val Lys His Val Val Pro Met Asp Val Ile Glu 1745 1750 1755 1760 Arg Leu Pro Glu Leu Met His Asp Pro Asp Ala Ile Tyr Arg Ser Ala 1765 1770 1775 Thr Glu Arg Asn Ala Val Val Met Leu Leu Asp Ala Val Asp Lys Asn 1780 1785 1790 Gly Asp Pro Val Val Ser Ala Val His Met Lys Ala Val Arg Ser Arg 1795 1800 1805 Leu Glu Ile Asn Lys Val Ala Ser Val Tyr Gly Thr Glu Asn Gly Lys 1810 1815 1820 Lys Leu Lys Ser Met Glu Met Thr Gly Leu Thr Leu Tyr Arg Arg Glu 1825 1830 1835 1840 Lys Leu Ser Arg Asp Asn Leu Leu His Arg Gly Leu Gln Leu Pro Lys 1845 1850 1855 Gly Glu His Ser Tyr Arg Gly Ser Ala Asp Lys Ile Leu Tyr Pro Glu 1860 1865 1870 Asp Ile Arg Lys Gly Pro Tyr Tyr Ser Arg Thr Ser Ser Leu Thr Pro 1875 1880 1885 Glu Glu Thr Ile Ala Ser Arg Phe Val Arg Gln Met Gln Asp Lys Phe 1890 1895 1900 Gln Val Leu Lys Ala Val Gln Glu Asn Ile Arg Lys Thr Gly Gly Lys 1905 1910 1915 1920 Val Asp Asp Ser Asn Asn Ala Tyr Met Ala Glu Glu Leu Phe His Gly 1925 1930 1935 Lys Ala Glu Asn Asp Leu Asn Val Met Lys Glu Arg Tyr Val Gln Pro 1940 1945 1950 Leu Ala Lys Leu Leu Ala Asp Tyr Lys Ile Ala Gln Ala Asp Leu Asp 1955 1960 1965 Glu Tyr Leu Tyr Ala Arg His Ala Pro Glu Arg Asn Ala His Ile Ala 1970 1975 1980 Lys Ile Asn Pro Lys Met Pro Asp Gly Gly Ser Gly Met Thr Asn Ala 1985 1990 1995 2000 Glu Ala Ala Glu Ile Met Gln Arg Val Arg Asn Ser Gly Lys Gln Ala 2005 2010 2015 Gln Tyr Asp Arg Leu Ala Gly Ile Ile Asp Asp Met Leu Ala Arg Arg 2020 2025 2030 Arg Glu Leu Ile Arg Glu Ala Gly Leu Glu Glu Asn Gly Val Val Asp 2035 2040 2045 Ala Trp Gln Asn Ala Tyr Arg Tyr Tyr Val Pro Leu Lys Gly Gln Asp 2050 2055 2060 Val Asp Gly Val Val Ser Leu Pro Arg Thr Gly Lys Gly Phe Thr Ile 2065 2070 2075 2080 Gly Gly Arg Glu Ser Arg Gln Ala Met Gly Arg Ala Ser Arg Ala Gln 2085 2090 2095 Ser Pro Ser Thr Gln Ala Ile Gln Asp Leu Ser Glu Ser Leu Ile Arg 2100 2105 2110 His Arg Lys Asn Glu Val Gly Asn Ala Phe Leu Lys Leu Val Gln Asp 2115 2120 2125 Asn Pro Asp Lys Asp Tyr Trp Gln Val Phe Thr Asp Asp Arg Pro Asp 2130 2135 2140 Thr Met Arg Thr Ile Ala Glu Arg Lys Asp Gln Glu Thr Gly Glu Thr 2145 2150 2155 2160 Ile Arg Glu Val Val Glu Arg Pro Val Pro Met Ala Met Met Ala Asp 2165 2170 2175 Arg Tyr Phe Thr Thr Lys Lys Asn Gly Lys Thr Tyr Tyr Ile Lys Leu 2180 2185 2190 His Asp Pro Arg Leu Met Arg Ala Met Lys Ser Met Gly Pro Glu Thr 2195 2200 2205 Ser Asn Ala Phe Val Arg Thr Leu Gly Lys Val Asn Arg Phe Leu Ala 2210 2215 2220 Thr Val Asn Thr Ser Tyr Asn Pro Glu Phe Leu Val Ser Asn Phe Ile 2225 2230 2235 2240 Arg Asp Val Gln Thr Ala Val Met Asn Leu Lys Ala Glu Gln Gly Arg 2245 2250 2255 Ser Asp Gly Lys Leu Lys Gly Leu Asp Asn Leu Ser Ala Leu Ala Val 2260 2265 2270 Val Lys Asp Ser Arg Ser Ala Met Ser Ala Val Tyr Ala Ser Leu Arg 2275 2280 2285 Gly Lys Thr Leu Thr Gly Lys Gly Ala Gln Trp Gln Lys Val Trp Lys 2290 2295 2300 Glu Phe Val Glu Asp Gly Gly Lys Thr Gly Trp Phe Asn Met Gly Asp 2305 2310 2315 2320 Leu Glu Gly Gln Gln Lys Glu Met Asp Arg Leu Val Ser Leu Ala Lys 2325 2330 2335 Gly Gly Trp Lys Gly Gln Ser Ile Gly Ala Trp Asn Ser Phe Leu Asn 2340 2345 2350 Leu Val Glu Asp Ala Asn Gly Ala Val Glu Asn Ala Leu Arg Leu Ser 2355 2360 2365 Ala Tyr Lys His Ala Arg Asp Ala Gly Leu Ser Arg Gln Gln Ala Ala 2370 2375 2380 Ser Leu Ala Lys Asn Met Thr Val Asn Phe Asn Arg Arg Gly Glu Gln 2385 2390 2395 2400 Gly Ala Leu Met Asn Ser Leu Tyr Met Phe Ala Asn Ala Ser Ile Gln 2405 2410 2415 Gly Thr Ala Asn Leu Val Arg Thr Leu Gly His Leu Asn Gly Glu Gly 2420 2425 2430 Pro Leu Leu Glu Arg Leu Arg Trp Lys Asn Leu Asn Val Pro Gln Lys 2435 2440 2445 Ile Ala Leu Ala Ala Val Gly Ala Gly Tyr Leu Leu Gly Ser Leu Asn 2450 2455 2460 Arg Ser Val Ala Gly Glu Asp Asp Asp Gly Val Asn Trp Tyr Asp Lys 2465 2470 2475 2480 Val Pro Ser His Val Lys Glu Arg Asn Leu Val Ile Met Lys Ser Val 2485 2490 2495 Phe Gly Gly Lys Ala Gly Glu Tyr Trp Ser Ile Pro Leu Pro Tyr Gly 2500 2505 2510 Tyr Asn Val Phe Phe Leu Leu Gly His Thr Ala Glu Gly Val Ala Ala 2515 2520 2525 Gly Asp Leu Thr Ala Ser Arg Ala Ala Gly Asn Val Val Gly Gly Val 2530 2535 2540 Leu Gly Ala Phe Ser Pro Ile Gly Ser Glu Thr Ser Glu Thr Leu Ser 2545 2550 2555 2560 Gly Ala Leu Leu Lys Asn Ala Ala Pro Thr Ile Leu Arg Pro Phe Ala 2565 2570 2575 Asn Leu Ala Met Asn Glu Asn Phe Met Gly Ala Gln Ile Tyr Gln Glu 2580 2585 2590 Asn Met Pro Phe Gly Thr Pro Lys Pro Asp Ser Gln Leu Gly Arg Arg 2595 2600 2605 Ser Thr Pro Glu Ala Tyr Lys Ala Phe Ala Ser Trp Leu Asn Ala Phe 2610 2615 2620 Ser Gly Gly Ser Gln Tyr Arg Pro Gly Ala Val Asp Ile Thr Pro Glu 2625 2630 2635 2640 Ser Leu Lys Phe Trp Ile Asp Tyr Ile Ser Gly Gly Thr Gly Arg Phe 2645 2650 2655 Ile Ser Lys Thr Thr Asp Ala Ala Val Lys Ser Leu Asn Gly Ile Asp 2660 2665 2670 Ile Pro Glu Gln Gln Val Pro Phe Leu Gly Lys Ile Ser Gly Glu Val 2675 2680 2685 Met Pro Tyr Ala Asp Gln Gln Lys Met Tyr Asp Arg Met Thr Glu Ile 2690 2695 2700 Ala Gln Tyr His Ala Glu Leu Lys Ser Leu Thr Gly Ala Glu Arg Thr 2705 2710 2715 2720 Ala Phe Ile Asp Glu Asn Asn Gly Lys Leu Ser Met Asn Gly Leu Met 2725 2730 2735 Gln Asp Thr Arg Lys Arg Leu Lys Asp Leu Arg Lys Gln Arg Asp Ala 2740 2745 2750 Ile Tyr Ala Asp Ser Thr Leu Ser Leu Ala Gln Gln Ser Ala Met Val 2755 2760 2765 Lys Ser Val Glu Arg Asp Met Lys Ile Ala Val Asp Arg Phe Asn Arg 2770 2775 2780 Glu Tyr Asn Lys Lys Val Gly Val Asp * 2785 2790 <210> 328 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(58537..58722) <400> 328 Met Phe Thr Pro Tyr Arg Arg Gly Thr Ile Pro Ala Ile Arg Ile Ala 1 5 10 15 Asp Gly Thr Ile Gln Ala His Asp Asp Ile Asp Glu Glu Phe Phe Gln 20 25 30 Pro Val Leu Asp Gly Phe Leu Ile Ser Lys Tyr Thr Pro Phe Asp Ile 35 40 45 Leu His Ala Leu Lys Asp Gly Val Leu Gln Arg Thr Gly * 50 55 60 <210> 329 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(58802..59146) <400> 329 Met Lys Lys Val Leu Ile Ala Ala Leu Ile Ser Gly Val Ser Phe Gly 1 5 10 15 Ala Phe Ala Gln Gln Gly Gly Phe Gln Gly Pro Glu Ala Glu Arg Ser 20 25 30 Thr Val Ala Gln Ala Lys Glu Leu Lys Asp Asp Ala Trp Val Ile Leu 35 40 45 Glu Gly Ser Ile Val Lys Lys Val Gly Asp Glu Arg Tyr Glu Phe Arg 50 55 60 Asp Asn Ser Gly Thr Ile Val Thr Asp Ile Asp Asp Ser Ile Trp Ala 65 70 75 80 Gly Gln Asn Val Ser Pro Lys Asp Lys Val Arg Ile Glu Gly Glu Ile 85 90 95 Asp Lys Asp Leu Ser Ser Val Glu Val Asp Val Lys Ala Leu Lys Leu 100 105 110 Leu Lys * <210> 330 <211> 71 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(59266..59478) <400> 330 Met Leu Asn Thr Cys Arg Leu Ala Ser Tyr Val Pro Lys Gly Lys Glu 1 5 10 15 Lys Gln Ala Met Lys Gln Gln Lys Ala Met Leu Ile Ala Leu Ile Val 20 25 30 Ile Cys Leu Thr Val Ile Val Thr Ala Leu Val Thr Arg Lys Asp Leu 35 40 45 Cys Glu Val Arg Ile Arg Thr Gly Gln Thr Glu Val Ala Val Phe Val 50 55 60 Asp Tyr Glu Ser Glu Lys * 65 70 <210> 331 <211> 132 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(59712..60107) <400> 331 Met Glu Asn Glu Gly Asp Asn Ile Ile Thr Leu Val Gln Pro Lys Arg 1 5 10 15 Asp Glu Glu Lys Leu Leu Asn Ile Thr Val Thr Gly Arg Lys Asn Tyr 20 25 30 Thr Gln Gln Ser Cys Lys His Arg Ala Ile Glu Val His Glu Gln Asp 35 40 45 His Val Ile Leu Cys Leu Gln Cys Gly Cys Val Val Asp Pro Phe Gln 50 55 60 Tyr Val Leu Arg Cys Ala Asn Asp Gly Glu Ala Val Val Arg Glu Ile 65 70 75 80 Arg Gln Leu His Asn Arg His Asp Gln Leu Arg Glu Ser Val Ala Ser 85 90 95 Leu Glu Arg Glu Glu Lys Asn Thr Lys Ala Arg Leu Arg Ala Ala Arg 100 105 110 Thr Ala Ile Leu Tyr Ala Glu Asn Asp Leu Lys Asn Ile Glu Gln Lys 115 120 125 Val Asn Gln * 130 <210> 332 <211> 220 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(60107..60766) <400> 332 Val Leu Glu Leu Leu Asp Glu Arg Glu Arg Asn Gln Gln Tyr Ile Lys 1 5 10 15 Arg Arg Asp Gln Glu Asn Glu Glu Ile Ala Leu Thr Val Gly Lys Leu 20 25 30 Arg Val Glu Leu Gly Ala Ala Glu Asn Asn Leu Ile Asp Ser Glu Cys 35 40 45 His Val Ala Glu Leu Glu Glu Ala Leu Arg Asp Lys Gln Ala Leu Leu 50 55 60 Glu Ala Ser Glu Lys Arg Ile Ala Glu Leu Glu Ala Glu Leu Val Ser 65 70 75 80 Gln Thr Tyr Lys Leu Pro His Thr Gln Phe Glu Gln Ile Ala Asn Leu 85 90 95 Tyr Glu Met Gln Phe Asp Asp Gly Arg Thr Cys Ala Phe His Thr Asp 100 105 110 Ala Gln Lys Ala Glu Gln Trp Leu Gln Ala Cys Asp Gly Asn Arg Val 115 120 125 Gln Glu Tyr Val Lys Leu Glu Arg Leu Gln Asn Ala Leu Ser Gly Asn 130 135 140 Ser Pro Val Thr Pro Asp Gly Trp Ile Ser Cys Ser Glu Arg Met Pro 145 150 155 160 Asp Thr Lys Thr Ala Val Leu Val Ala Val Glu Phe Asp Arg Lys Gly 165 170 175 Asp Trp Arg Met Lys Trp Ala Thr Tyr Ile Pro Gly His Pro Asp Ala 180 185 190 Asn Asp Gly Trp Ile Ile Pro Gly Ala Ser Trp Lys Pro Ser His Trp 195 200 205 Met Pro Leu Pro Glu Pro Pro Gln Glu Val Asn * 210 215 <210> 333 <211> 73 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(60787..61005) <400> 333 Met Ser Lys Ile Asp Tyr Gln Ala Leu Arg Glu Lys Ala Glu Lys Ala 1 5 10 15 Thr Lys Gly Ser Tyr Ile Val Gly His Thr Ser Val Asn Gln His Gly 20 25 30 Asn Leu Thr Gly Val Phe Val Cys Gln Lys Trp Lys Gly Glu Pro Gly 35 40 45 Gly Val Ile Ala Glu Cys His Val Asn Cys Leu Val Glu Thr Asp Ala 50 55 60 Gln Ala Tyr Ala Thr Leu Asn Ser * 65 70 <210> 334 <211> 95 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(60992..61276) <400> 334 Val Asn Ile Asn Thr Thr Ile Thr Ile Asp Thr Ala Leu Asn Thr Gly 1 5 10 15 Leu Ala Leu Leu Gly Tyr Phe Tyr Ile Met Phe Cys Ser Gly Arg Trp 20 25 30 Leu Ser Leu Leu Phe Met Lys Lys Trp Asn Lys Arg Arg Lys Gln Glu 35 40 45 Gln Arg Gln Lys Ala Ile Asp Ala Phe Phe Glu Ala Phe Gly Ile Asp 50 55 60 Gly Met Glu Pro Gly Asp Pro Ala Arg Ala Ile Ser Arg Gly Gly Val 65 70 75 80 Val Ile Leu Val Tyr Arg Ser Glu Glu Lys Asn Glu Gln Asp * 85 90 <210> 335 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(61273..61494) <400> 335 Met Ala Asp Ile Ile Asp Asn Ala Ala Glu Ile Glu Glu Leu Gln Arg 1 5 10 15 Asn Leu Ser Leu Gln Lys Tyr Lys Ser Asp Ser Asn Ala Pro Ser Ala 20 25 30 Thr His Cys Cys Glu Cys Gly Asp Pro Ile Asp Glu Arg Arg Arg Leu 35 40 45 Ala Val Arg Gly Cys Arg Ala Cys Ala Ser Cys Gln Gln Asp Ile Glu 50 55 60 Leu Ile Asn Lys Gln Arg Gly Val Lys * 65 70 <210> 336 <211> 210 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(61542..62171) <400> 336 Met Thr Ser Gln Leu Ile Pro Val Phe Asn Gly Thr Ile Ala Asn Glu 1 5 10 15 Thr Thr Leu Leu Val Asn Ala Arg Asp Leu His Thr Phe Leu Gly Val 20 25 30 Gly Lys Arg Phe Ala Ser Trp Ile Thr Glu Arg Ile Glu Glu Tyr Gly 35 40 45 Phe Val Glu Asn Gln Asp Tyr Ile Ala Ile Ser Gln Lys Arg Glu Ile 50 55 60 Gly Tyr Gly Arg Gly Lys Lys Asp Tyr His Leu Thr Leu Asp Thr Ala 65 70 75 80 Lys Glu Thr Ala Met Val Glu Arg Asn Glu Lys Gly Arg Gln Ile Arg 85 90 95 Arg Tyr Phe Ile Glu Cys Glu Lys Lys Leu Arg Asn Met Gln Ser Ala 100 105 110 Gln Ala Glu Pro Gln Gln Gln Phe Thr Asp Glu Glu Ile Ile Leu Leu 115 120 125 Cys Tyr Met Gln Leu Trp Met Glu Lys Ala Gln Asp Leu Ser Lys His 130 135 140 Leu Tyr Pro Ile Met Lys Glu Leu Asn Ser Ser Tyr Thr Asn Lys Leu 145 150 155 160 Tyr Asp Ile Ala Phe Glu Thr Ile Tyr Met Val Thr Lys Asn Arg Asp 165 170 175 Val Leu Leu Arg Glu Ala Ala Arg Leu Asp Gln Ser Ser Phe Val Val 180 185 190 Gln Arg Ala Arg Pro Met Leu Lys Ser Leu Arg Ala Arg Gln Phe Glu 195 200 205 Phe <210> 337 <211> 58175 <212> DNA <213> Escherichia coli O157:H7 <400> 337 ttctctgcaa aacctctgca aaacccctct gcaaaactgg tcatcaaatg accagttttt 60 tccattcctt accgcgtgcg tcgttgtaaa tatcggtcat tttttgattc gaatggccta 120 gcaaaatttt ggtatcaacc ccctgctctc tgaacaatcg ctctgataaa gatctctgct 180 catggaaaga gggaggggtg ccattagcac gccagttgta atccacagaa tcccgggctt 240 ttttaaatgc aacggttaat gttgctggct taaccatccc gccgcgctta gctgtccctt 300 tcgcgtgatg gtggtgcaat agccacggac taagaacgca atcgcggcag gatgacacca 360 catcatccag ggtgagattt aatttatcgc aacgcagagc cagagggatg gcaatccggg 420 ttcctgtttt ttgctgttcg acatgaagat aaccatcccg gatatccgaa aattgcattt 480 tgcaaatatc tgaaaggcgc tggcctgtca tcagtgccag cagcataccg cgctgtaaaa 540 agtaaccatc cttttccgct gcgttataaa tcatcatcca ctcatcaaaa gtcagtcgct 600 gtcttgatat ccgcacctgc ggtttttttg ccgattctgc agggttaaag cctggcggga 660 catcgcccgt ttgctgagct tcccggaaaa catcgatcag tactttcctg aaaatttgtc 720 ccattctgtt atgtcctctg gccttgtact cttccagtac tgataccaca tcttttacgg 780 ttatggcatc taacggtctg gtgccaaaac gttcatcaaa taccctgaga ggggccgctt 840 tctgtttcag cgtgttgagt ttgatctcgc cgttttcata tctttcctgt tgaatttttc 900 tgtaattatt cagaaaaatg gtaacggttg atgaaccgcc ggtatcacta ataattttct 960 cctgcagact gagcatttgt tccatttgct gccgggcaag acggctgttc gcttctgctg 1020 caatagtttc tgccagtttc tggtcaatac tgccgagacc gtgatttttg cctgttatgg 1080 gatgcctgta acgccagtaa actttgttat ttcttttgtc aaaatacgga gataatcccg 1140 gaacatcggt tttatatttt cgcgggcgcg ccatcttcca gtatcctctt caaagcaggg 1200 tgatctgtgg cgatcacctc cggcttgttt accattccga caaagcgagc ttgcggatcc 1260 actcgccagc gtcttccaac ttttttgggg agaggaaata tcattccggc tttagcgtat 1320 ttacttaacg tactcggagt tgggaccggt tcactgaatt cctcttttgc ccactcagtg 1380 agcagaataa gtcttgccat gagcgtcgtt cgctaatcat ggtcgccgcc actatagctg 1440 gtgggcaacg accggggttg aacattaaaa atcagcctga ttcgggatca gtttttgcca 1500 gataactgaa acgtattttg cctggtaacg ggcgtcatca agtgcattat ggcgctcacc 1560 ttcgaatgga atagccgttc tggcatcgaa gtctatggct ttccccagct caacgattgt 1620 gcgtacatcg cgatcgttgt agtaacgcca cgggcagggg atcccctgcc gttcgtatga 1680 acggcgcaaa atcgtgttgt cgaagttggc tccatttccc cagacctgaa caaaaaattc 1740 accggagttt tcgtcgataa attcccgcaa ttgtaatagt gcatcatcta acgggatttc 1800 atcggtcata atggcagatt gcgcttcgcg tgattgctta agccaccatt taatggtgtc 1860 ccgatcaatg accccgccag cagtttccag atcgatagtc ttactaaatt ccggtcccat 1920 atctccggtt tgcggatcga aaaatattgc acctattgag atgatcgggg catcaggatt 1980 ttttcccatg gtttcaaggt cgatcattag atggtcacac gtcctgctgg tggatgtgat 2040 ttcttgatga ccgttcacct taattgagtg atctgccgtc tcgccagttt cattatcgct 2100 atcgtgatgc tgattgccgt cagtgttctc cttgtgtgga tgttcagcgc cttccatttc 2160 ctccggatca tcttcctgaa cttcaacctg atactcttca tcgaatgttt cctggtatgt 2220 tgcgtcgccc atcaccgcgc cacaatcagg gcagttgccg ccgccggtct gaccgcaggc 2280 ggtgcagact ttttccggtt cctgttgcgc tactggctca ggttgtttcg tttctggctc 2340 gttttgttgc gtatttgggc tgttttgttc cgctttctgg tcgttctgtt ccgtttcttg 2400 ctggttctgg ttcacagaat cgcgggtttc aatccccttc acccatttcg gatcattcgg 2460 gtcgctaatc cctgcaacaa attcaccacg tgatgcggcg agcaactgat tggcgtcagg 2520 ctggctgata ttggctgcct gcataatttt ctttacttcg tcagcggtaa cttttaccgg 2580 ttctggttgt tcagaatttt gtgcggtatt tgcattttgc ggtaagcctg tgtatgtgcc 2640 attttttcgg gcaaaatatt cttcttttgt gatttcagta gccccggcag ccagcgcctt 2700 atccagacca gaaagtttgt ttgcgcgacc gtatttttcg ccatccttgt cggtgaagag 2760 gaagtagaac ggcccctcac gctctacaga tggttcgact tccactttgc attcggtttt 2820 ttcgttgtcc ggaattgccg tttccactgc atcagtttct ggtactggcg acgagagagt 2880 gtcagttgcg ctctgatttg ttccttcatc ttcaaacacg ccctttgtag tcaggtattc 2940 agtaatgtat ttgttcagtg ccacagggtc tttgtgaatg tcgatcggac gttcacggac 3000 aaggccaaaa atagtctggc ggtcgtagcg aagggcatca ggctgtttgc gcattgatgc 3060 cgagatacgc ttccagtctt cgcggtcgtt gtcgataact tcattttttg cccagcgatg 3120 gatgctgccg tcaatgtttc cggcatccac atcaccaggc cagagagcgt aggccagttc 3180 gtcatccagt gttttccatg tctgcttata ttcgcgacga atgactgcag tgacaggggg 3240 gattttttct gctgagtttt cagtgtgctg tcggtggact ctggcgcggg cgagatcaac 3300 aacagacgtg tattttccgg tttccttgcg ttcaccttcg cgacgttttt tccagatgcg 3360 catttctgcc tgaatttcgg gccatttggc accaggctta catttatgct taacccaccc 3420 gatggcatgc agcttaagct ccggatacat ggcgttaact tctggcattt tcatcaacgc 3480 ttcaacgata tgtccgtcga atgttgccat gtcttcctgc aacaattcct gcgcgctaat 3540 caccatatca acggtgatgt tttcacatgt gtcgaactta accatgacag cgttctgtac 3600 ttcaggggcc agcttgtcaa aagcgacgtt catcggatcg gattcagtct caaccgggac 3660 aaaggaagca gccccctcat cccagcggtt ttcctgcata tattcagcat cccaggaatc 3720 gagggcaggg cggggtatac cgggtttatc ctcgcaaaca agaaatttat aagcgcagtc 3780 ctgagcagcc ggataatgct ccaggaattg ccagtgaaat tttgcgcggg cgcgacgttc 3840 atcaccggct tcaatggcag tggctacagc gactgcacct tcttccttta ttgcctgttc 3900 gtccggaatg gcggcgcaaa taaagacttt actcattttg ttttacctca ttacagattt 3960 aagggtgaac aaatccctgc cattgctggc atataagaat gaaatcggat gtttattacg 4020 gaactgtttt aaagacctgc cgggatttcg ttattatcct ggtgaataac tttatcgaca 4080 gggtaacagt taccgggaat tttctgttcg gttgctgcag tcacacactc ctgcattgtc 4140 ctgtgaacac tgactgcaat atcaactggc tctccggaaa caagaaaaac tgtcagaaca 4200 agtgcaaatg ctgtattcat tgccagcatc ctttttgtat cggacgtaaa cgggccagca 4260 ttgaaagaat gcatatttta tttaataact cccgttcgtg ttttctcttg ttaatggcat 4320 cttcagtaaa tacagggtta ctgatagtga caccaatttc aaaacaacct tcagacgtat 4380 taacgtttgg taataacgtt tccattatcg cgtcctcaac aatgaatttt gtgatgcggt 4440 gcctggtgcc tccaggtgac gttaaccagt taacaattaa cgccggatac agagaatccc 4500 cccataacac tgtttttggt tttaactgtt ccgcgtgcgc ttagccgcat tcactgcatc 4560 acaaaattca ctttaaaaag ggcggacatc agttcatggg caaacagatg ccgccaaacg 4620 tcaccagaaa attgataaca gagggcgttg cagcggggtt gtcacttaag cgtatggtca 4680 acctgacaac ccggtgtcct caacggggaa ggaataaccc cgccatactt accgctgcgc 4740 catttcgcgt tatgctctga cttttcagag aaatatcctt tcagtaaact gtcagtgccg 4800 gatgttcacc cgtgtccggc gcacgcactc cacttcaccc gtggagaact ccttaattac 4860 caaccctcag gagggtgaat gttaaaatca actcttattg ctaaatgcct ttatcaaaat 4920 cgcatggtaa gcagcatttc aataggcgag tctgcagtta aaagtatttt cgaagagtac 4980 tttcccgggc atgattttaa taaatggaat accaaattac cgccagcagt ttcaacgcgt 5040 attctgaaag caaccgaaag agcaagtaca attcgcgtta actatttcat taaagatttg 5100 tgggatcttt gatatccaca gagcctaaag tatgtgcata tggatgtgct attatgcgcc 5160 ctcgcagatt tgcatcattt tctaaattca ctgaacgaaa cagggcatca acaaggctct 5220 gtacaatgca aaggcaatcg aagactgtcg ccgtttctgt tttgattgat gaaagaacat 5280 ggccattcac gcaaacagaa attacccgtt tattaacatc gctttcctgc ttttgattat 5340 cagaaccata tagcccagaa aaagcattgc gcacattacg aaccatatta tcgatggttt 5400 ctttttctgc ggtactaagg tcaagagtag ccagttgtga acgaactata ttcgatgcca 5460 tttcctgtaa tggcgttggt aaatctttaa attccattat tagcctcgtt ggttagctat 5520 taacgtgggt atgtaatcat tctggcaatg cttaatgccg ctgctttttc cagattggtg 5580 atatcctgct ccagagcgga cagattttca gcctgcttag ccctggcttc attggcccat 5640 ttcaggtcct gcaccgcctt aattttctgg tgcatccact cataaagttc atcatcggta 5700 tagtctggcg cgatgatgac ggggtctcgt ttctgcatgt cggctccttg tggttagcgt 5760 tgcctgcttt ttaaccacgt caggcgaggt ggtatcctct gaggggtctg ttactcgaga 5820 ggaaattggt tatgaataca atcaagtttt cttgcccaga atgtggtggc taagtctttg 5880 acacatcctt taagccgcag ggctctgaca gtttcgcggg agccatctgc aaaaattgtg 5940 gtcaccttgt aactgaagat gagtcctcgc agttcgatga cgaaatcgtt gacaatatct 6000 tcggtgcact caccagagac tttctgaagt aaaggcgcat accgcttagt taccgctctg 6060 ataactctta cctgtccggc aatggcgctg atatcaatat aaagcgccat cgctgtttct 6120 ttgctgatcc ctggacgcct tccattctga tgtttgactc gcccactgag aaatcctctg 6180 cttcccctta acgccgggta gcggaactgt ttgctgagaa caccgtgcgg tgtcttgatg 6240 agtagaattt agaatagcct aagagttatg gtcaagcttt ttgtgtagaa aaacctaagc 6300 ttcttgatgt aaaaaacaca agtatttgaa agtttgtgct ttttattaca gagagttgcg 6360 aaaaaaaggg gggttattta tttgcgcttc ttttgcgagc tttgagtagt tcttcaaaaa 6420 gtttgttgaa attctcaact cgagcacgca tctctgacaa cagagccttt tgctctgact 6480 caggcagtgc gtcgaacagt tgaagcaact ctttttgatc ttctgtcaga ttgactggct 6540 gattatctgg gatcggttcg cctggttgct tatcttcatc tccaaaaaga agccaagtcg 6600 gcgagcactg aagcgcctgg ctcagtgcga ataatctctt ccccgctggc tgtgtttcat 6660 ctctttccca ttgagaaatt gttacgtgag cgactttgac cagcttacct aatgcggcct 6720 gagacagttt taattttttt cgcctgtata agaggcgagc accgaaggtt tcgtttttca 6780 tattaggtaa ttctaatttt tcttgactta ggtttctcta cgatctagtt tccttaggaa 6840 aatctaaggg tttcgatatg ttgaaaattg atgctatagc gttttttggc agcaaaacaa 6900 agcttgccaa tgtcgcagga gttaggctgg caagcgttgc tgcatggggg gaactggttc 6960 ctgaaggtcg cgcgatgcgc ctgcaagagg catccggcgg ggaacttcag tacgacccca 7020 aagtttatga cgaatatcgt aaggcaaagc gggcggggcg gttgaacaat gaaaatcacc 7080 actgaacagg tttgtgaggc tctggatacc tgggtatgcc gaccaggaat gacacaggag 7140 caggcgacga tattaatcac ggaagcattc tgggctctga aagaacgccc gaacatcgat 7200 gttcaacgcg tcacgtttaa tgatggcgag gttgatcaac gggcgctggg cgttaaccgg 7260 gtgaagatat tcgaacgctg gaaagctatc gacaccagag ataagcgtga caaattcacg 7320 gcgctgattc cggcaattat ggaggctatc cggatcagcg atttcagatt gtattgtgaa 7380 attactgacg gaaaaagcat tacgtacatg atcgccgggt taaacaaaga atatggcgat 7440 gtggtggagt ccgggctgct ttttgcggat ccagttgttg tggaacgtga gactgacgag 7500 cttatagaaa aagctattgc tttcaagcac gcgtatcgtc agcaatacca atattacttt 7560 gcagataaac aaatgtctgc caggggggcg tatgagtatc gatgcactac gatgggctaa 7620 aaaggtgaaa accggcagtt catccagtaa gtcagtattg acctggcttg ctgatatgtg 7680 cggtgccgat ttgtgtgcat acccgtctgt atctgcactg gcagaagtaa cggaactgaa 7740 caaaaagact gtgcaggaca gcttacgaca cctgatggag attgggttaa ttgttgatac 7800 cggtgagaga aaaggcagaa caaagcaaat tgtggtgtac cgacttatcg gtgtagaaga 7860 aagtgttgcc gagcctgaat acacccaaaa acgggagtct ttaaaggtgg gtaaaattgg 7920 tgctgttaat aaaaacagta ccgaaaatgg ttatgtttca gcacaaaaca gacccaaaaa 7980 cagaactctt agctgcatgg aaaataacca aagacaccca aattttccat caaagacacc 8040 caaaaacgga tcacggaacc caaaggaacc caaagatcta aaccccacac ataacgcacg 8100 cgagagtgct ccgaccagtg agcaggaagt tttgtcgtta caggcagccc cccctgtatt 8160 cctgtatggc ctgagcgaac ccatcggaaa attcccgatg agcgatagct ggtatccgtc 8220 acgggatttt cgacgacggg ctgcgttgtg ggggatggct ttgccggaga cagaatttac 8280 acctgctgaa cttgccgcct tccgggacta ctgggcagcg gaggggaaag tgtttacgca 8340 gattcagtgg gagcagaaat tcgcccgtca cgtaaatcac gtcagggcgc aggttaaacc 8400 agtcagcaaa ggggtaaacc atgcagcagc accaggtggc accgcatcac gggcagttca 8460 ggaaattcgg gcagcacgtg agcagtggga acgtgaaaac ggatttatca gcgacggaaa 8520 cggcctggaa gctgtgggaa ctcatggggg tggtttattc gaaccgctgg atccagaaga 8580 acggggccgc accttcgaag ctctggattg cacagattgg cgcgatgact gagcagcaaa 8640 tccggcaggt ctgccgccag tgcatggacc gctgccgggc gggtgaaaca tggcctccgg 8700 acctggctga gtttgtggca ctgatttcga aaagcggagc caatccattc ggtctgacgg 8760 tggatgctgt gatggaggag taccgccgct ggcgcaatga gtcctggcga tacgacggaa 8820 gtgataagta cccgtggtct cagcctgtgc tgtatcacat ttgcctcgag atgcgttcaa 8880 aggggattga gcgccagatg accgaagggg aattaaaacg gcttgcagaa cggcaactga 8940 cgaaatgggc aaagcatgtt agtaacggcc tgagcgttcc gccagtccgg cgacaactgg 9000 cggcccccaa acgcccgtcg gggccaacgc caattgagtt gctgaaacag gaatatgaac 9060 gccggaaagc ggctggtttt gtttgagttg agaagtgatt ttttaccggg aggaaattta 9120 tggagactgt ttttgacgca ctgaaagcga tgggaaaagc cacgtcggta tagctggctg 9180 cgcgacttga tatcagtcgt gaagaagtac tgaacgagct gtgggaactg aaaaaggctg 9240 gcttcgttga taaaagcgta tacacctggc gtgtggctga taacaacgtt cagcaggaac 9300 agccagcgcc agaagaaacc accacggcaa cagaagcgaa aatctcagag tgcgatttaa 9360 ccgcgacgat tgaacaacgc ggaccacaaa cggcggatga actggctacg ctgttcggta 9420 caacatcccg caaagttgct tcaacgctgg caatggcaat cagcaaaggt cgtctgattc 9480 gcgtaaacca gaacggtaaa attcgttact gcataccagg tgataattta ccagcagagc 9540 cgaaagttga atcggtagcg gaaaccgatg gtaaagcctt tcctcagcca gccggtgttg 9600 cgttaccggt acagaaagat gcaacacagg aagatattaa aacagaaact gtggcggaca 9660 ttgtgcagtc gctgccatcg tttactgcaa cgcgagaaga tgatttgatt ttgccatcgc 9720 tgcatatggc aaatcgcgaa ctgcgtaggg cgaagaatca tgtccagaag tgggagcgag 9780 tctgcgccgc gctgcgggag ctgaacaagc accgggatat ggttgccggg atttgtcgga 9840 agtccgggca atgagcggat ggtgcaggcc tgaaatcatg atactaacaa tgaaggtaaa 9900 atgcatcggc agtctgattg gtcgtagtga ggcggcggtc aggatgaaag cccaggttaa 9960 gggaataagc ctgattctgc ggggtgattt tcaccagtca acaaaatatc cgtagcgcga 1002 0 taacggtcaa aaattatggc gctgacactt ttgtgccact ggagatgact gtacctaagt 1008 0 tcaggggaga agaacacgtc cggtgggatg gtcgggccag atttaaaggg caggtcatgg 1014 0 ctccagcctg tacgctggca atggaggctg cctggcggga aattgatatg ggaaccacgc 1020 0 cactcaggga tttactgccg gtccagagaa taaattcctg ttacggttac accactgtga 1026 0 tcttgcaagt gcaggaaagt aggtctacac ggtaacgcga gtgcgtgtaa cttttgatgt 1032 0 cattcccgta gaaacaccgg acaaattttc gctgacaggt catgcagaag gtataaatct 1038 0 gcagattatg gacaattacg gatatccggc aagagccgga aaaagcatgc cgcctctaat 1044 0 tctcagtgga agatggactt gattatactc attgcattgt cagaaatagt tatccattaa 1050 0 aggctggcta ttccaaacag gatgttgatt acaaaaatgt aatcaacatg taaggtttat 1056 0 actcttcaat atgcgtataa ttttccttat tttgttgact ttaaataaca agctatgcac 1062 0 gaggtaaagt cggataagtt tatctggatg taatatatat tatttgtagt gtttataact 1068 0 ttatttcatg ataaccaata aaaggagttt tttatgagga acataatggc aggtttttta 1074 0 atattcctgt cttctgctgc ttatgctgat atcaatctgt atggtcctgg tggcccgcat 1080 0 acagccttgc ttgatgcagc caaactttat gccgaaaaaa caggtattat agtgaacgtt 1086 0 cattacggcc cacagaacaa atggaatgaa gatgccaaaa aaaatgcaga tatcttgttt 1092 0 ggcgcatcag aacaatctgc tctggctatc attcgggacc ataaagacag cttcagtgaa 1098 0 aaagatattc agcctcttta tctgcgaaaa agtattttac tggtaaagaa aggtaatcct 1104 0 aaaaatatcc ggagtattga cgacctgacc agacctggga ttggcgtaat tgttaatgat 1110 0 ggtggtggta ccagtaatac atcaggcact ggcgtctggg aagatattgc cggacgtaaa 1116 0 gggaatatag aaactgtcgc cgcaatccga aaaaatatta ttttatatgc gcccaatagc 1122 0 ggaactgcac gtaaggctct tgagaatcag cctggagcag atgtctggat aacctgggct 1128 0 gactgggcag ccagtaatcc agaaattggt gatgtcgtgg aaatagcgcc agactacgtg 1134 0 atatggcgtg atatgaacat tacagtacgt caggatgcaa atgatgaaac ccgtcgattt 1140 0 gcagaatggc tacaaaccga tgaagcggcg cctgcattca aaaaatatgg ctggaccagg 1146 0 aaaggcactt gacatcctcg tccttcagga cgtggattct ttttccggat gccgcgccag 1152 0 cggcatgtag gggcagctca caaaacggaa aaaattgtac gctaagcctc gccaggtgaa 1158 0 ctgaattcat tccgatatgg gaattcccat atcgggcgaa aacggtttgc tgtaacggca 1164 0 gagttaagta ggattgctgc gggtgcttga ggctatctgc ctcgggcatg aacaccaacg 1170 0 gcagatagat aaaagcccca cccgactata aatcgaagtg aggcccctat atgctcgtca 1176 0 catatagatt gcctcttacg gaccgaaagg tcaaggagaa gcaggctatg aagcagcaaa 1182 0 aggcgatgtt aatcgccctg atcgtcatct gtttaatcgt catagtgacg gcactggtaa 1188 0 cgaggaaaga cctctgcgag gtacgaatcc gaaccggcca gacggaggtc gctgtcttca 1194 0 cagcttacga acctgaggag taagagacca ggcgggggag aaatccctcg ccacctctga 1200 0 tgtgtcaggc atcctcaacg cacccgcact taacccgctt cggcgggttt ttgtttttat 1206 0 tttcaacgcg tttgaagttc cggacggcgc cggaatagaa tcaaaaatac ttaagtagcg 1212 0 cgcagggaga agagggatgg accccgaaca ggggagtgct atttatctgg aaggattctg 1218 0 ttgatgagaa tcgaagaatt acgtgaaatt tttagtgaag atggcctcta tactgtgcgc 1224 0 gttgagaagg gcgctattgt cagccactgc cgtattaaat gtttacagtc tcaacaaagg 1230 0 aagagtggag ctgcgttaat tcattttgtg gatgggcttg tgacggatgg ttttattttg 1236 0 cgtgcaaatg aatttgtcac atcgttgccg tctctgaaag aagctgggat taaggctggt 1242 0 ttttctgctt ttgaagatta gtgaattcat ctacaattca gcgcagggct gaacccctgt 1248 0 tgagtaacac tgtgccaccg gagaaagccg atggcgcaaa attccagact acacaattct 1254 0 gataattcag ccgtctttgc cagcaggcac gggcggcgtt ctcatgcatt caaatctgac 1260 0 tggttccggc acgccccatg cactgaagaa caggccgaat ggctgattca gaactaccgc 1266 0 agacgtgggt atgagtttag gaaagccctc agcctcgatt atcgtcactg gataatctac 1272 0 gtcaggctgc cgtactccga gcgcccaccg cgtccgtccc gcacattcca gcaacgcatc 1278 0 tggaggtaac gtgcgggtat tacttcgacc tgttccggta ccggaacttg gggtggtggt 1284 0 ccttaaacca ggccgtgaat ccatgcaggt attccataac cctcgagtgc ttgtggagcc 1290 0 ggagccgaaa agcatgcgcg gtctgccgtc cggcatcgtc cctgccgttc gccagccgct 1296 0 ggcggaggat aaatcattac tgccgttttt cagcaatgag cgtgtgattc gtgctgttgg 1302 0 tggcgctggt gcactgtctg actggctgtt gcgtcatgtc aaatcctgcc agtggcctca 1308 0 tggtgactat catcacagtg aaaccgttat tcaccgttat ggtaccggcg caatggtgtt 1314 0 gtgctggcac tgcgacaacc agctgcgtga ccagacatcc gaatcactcg agcaacttgc 1320 0 tcatcaaaac ctgtcagcat ggatgattga cgtcatcggt cacgcaataa gcggtacgca 1326 0 ggagcgtgaa ttatctctgg ctgaattatc ctggtgggcg gtccgcaatc aggtggcgga 1332 0 cgcgctaccg gaagcggtat tacgtcgttc gctggggttg cgtgcggaaa aaatccgctc 1338 0 aatgtaccgt gaaagcgaca tcgtaccggg agagcagacc gccaccatca tactgaagca 1344 0 gcgcacaaaa aatcttgcgc cgctgcctca cgcccaccag caaaacccac cacaggaaaa 1350 0 gacggtggtc agcattgccg ttgatccgga gtctccggaa tccttcatga aacgacctaa 1356 0 acgtcgccgc tgggtaaatg agaaatacac acgctgggta aagacacagc cgtgtgcgtg 1362 0 ttgtggtaag ccagcggacg atcctcatca tctgattggt catggtcagg gcggaatggg 1368 0 aacaaaatcc cacgatattt tcacgctacc gctgtgtcgg gagcatcaca acgagcttca 1374 0 tgcggatccg ctggcgttcg aagaaaagca tggttcccag gttgatttaa tttttcgttt 1380 0 tcttgatcac gcctttgcga ctggcgtgct cgggtaaaag aggtgactga tgctcataga 1386 0 tttggtttta ccttacccgc cgacggtgaa cacttactgg cgacgccgtg gcagcacata 1392 0 ttttgtatca aaagccgggg agcgttatcg ccgggcagtg gtgcttattg ttcgccagca 1398 0 gcgactgaaa ttaagcctgt ccggacggct ggcaataaaa attattgcag agccaccgga 1404 0 taagcgtcgt cgtgacctgg acaatattct gaaagcaccg ctggatgcgc tgacgcatgc 1410 0 gggagtgtta atggacgatg agcagtttga tgaaatcaat attgtacgtg gtcagccagt 1416 0 atctggtgga cggctgggtg tgaagattta caaaattgag agtgagtgag cgtaaatatg 1422 0 atatatccgg aaattacagg caaaagcggc gaacatttac gcctgaacac gctggaagca 1428 0 gtctggatcc aggggaaatt acggatgtgg gggcggtggt cgtatatcgg tgggggtaaa 1434 0 tccggaaata tgtttaaccg gttactggtt tcgaaaaagc tgacgaaaac agcagttaat 1440 0 gaggttttac gcagcatgaa gaaatccggg ctggaaaaac cggaacttga ggcatttttt 1446 0 cgggatatga ccagagggaa gcagaagagc tggttgtcac attgtacaga cacagaggcg 1452 0 ttgattattg atcgcgttat cagtgaggtg cttggggaat atcccgggct aatcaatatt 1458 0 ctccggcaaa ggtacgaagg acggggaatg agtaagagaa aaatggcaga atgtttaaat 1464 0 cgtactcacc cggaatggtg tttcagcaca tgtgagaaac gtattgcagg ttggttagcc 1470 0 gtggctgaac acatgcttta tgtacctatg cacgattcat ttcgataaaa aaagcttgct 1476 0 tttttacgca gaaacagctt gaattcctgt aagcttcgca aagctgtatc gcgaggcgaa 1482 0 atgcaagttt tttcgcacaa ggaagccacc ggaaggtggt ttttttgtgt ccgtaatata 1488 0 cagcagcgca ataaattcgc tggtggttat taataccgtt ctttcaggtt gctggctttt 1494 0 tcgacaagag ttattggtgt gtcacgttaa ccggaaaagg gaaaaagaca tgctgaaaca 1500 0 gcaggatatg acagaaaccg ccagagtggt gtttaatgaa ttaagcgtta ccgacccggc 1506 0 gacagtcggg gagattgcgc agaatactta cctttcacgc gaacgctgcc agttaatact 1512 0 gacccagctg gttatggcgg gtctggcaga ctatcagttt ggttgttaca gacgccttca 1518 0 gtcctgaagg cttttttatt tgtggtaaat gggcggctgg tgggtgtaag gggcacccac 1524 0 cagccatctg ctcatgcgtt gggttcacaa gcaaacctca ggcccactgc tttgcgcaaa 1530 0 agcagaatga gcctatcaga gacaggctta atgatccatg cttaatactg taaaaatatc 1536 0 cagttgtgag ttaatcaacg ccgactgcct ggaatttatg cggtcgttac ccgaaaattc 1542 0 tgttgacctg atagtcacgg acccgccgta cttcaaagtg aaacccgagg gctgggataa 1548 0 ccagtgggcg ggtgatgaag attacctgaa gtggctggac cagtgtcttg cgcagttctg 1554 0 gcgggtgctg aaacctgccg gaagtcttta cctgttctgt ggccatcgtc tggcatctga 1560 0 caccgaaatc atgatgcgtg agcggtttaa cgtgctgaac catatcatct gggcaaagcc 1566 0 gtccggacgc tggaacgggt gcaacaagga aagcctgcgg gcgtatttcc ccgccacaga 1572 0 gcgcattctg ttcgcagagc attatcaggg gccgtatcgt ccgaaagatg ccgggtatga 1578 0 ggcgaagggt aggacactga aacagcatgt gatggccccg ctgattgctt actttcgtga 1584 0 tgcgcgcgct gtcctgggga taacggcaaa acagattgca gatgccacag gaaagaaaaa 1590 0 catggtgtcg cactggttca gtgccggtca gtggcagctg ccgaacgaaa gcgattatct 1596 0 gaaattacag gcactgtttg cccgggtggc agaagagaag catcagcggg gtgaactgga 1602 0 aaagccccac caccagctgg tggatacgta tgcctctctg aaccgacagt atgcggagct 1608 0 gcagagtgaa tataagcatc tgcggcggta tttcggtgtg acggtgcagg tgccgtacac 1614 0 cgatgtgtgg acgtataaac cggtgcagta ctatccaggg aaacatccgt gcgaaaaacc 1620 0 ggcagaaatg ttgcagcaga taatcagcgc aagcagtcgt ccgggagacc tggttgcaga 1626 0 tttcttcatg gggtcggggt cgacagtgaa agcagcgatg gcgctgggac gtcgtgcaac 1632 0 tggcgttgaa ctggagactg aacgttttga gcagacggtg cgggaagtac aggatttaat 1638 0 cattcgtaac ggatgagatt gcggagttaa tcatgcgtcg ttattattca gcaatcggcc 1644 0 ctttagctca gcggtgagag cgagcgactc ataatcgcca ggtcgctggt tcaaatccag 1650 0 caagggccac caaccgccac tagctcatca ggaaagaacg tcaccctgtg cgagattcgg 1656 0 agtccccggt ggcggtccat tatcggtatt ctgcgttgtt agctcagccg gacagagcaa 1662 0 ttgccttcta agcaatcggt cactggttcg aatccagtac aacgcaccac accacactta 1668 0 tctgccctga ctctcttttg cgggcttttt attacaggaa agacaccgga cagtgaaatg 1674 0 ttaaatgcct cacaattcag gcagttgact gttgcctgac atgctgagcg tttgttaaaa 1680 0 aaatcctgca tgatgaatcc ccctgagcgg cggggcataa tgacagatgt ttggttgcgt 1686 0 attgtatagg caagttgcgg attctgtctg gtcattgcag aattcaccgg gaggcacccg 1692 0 gcatcatgct gtatacagag attaggcata tatccaggct tctcatcgca ggagcctttt 1698 0 tacatgcaaa aaaaagcccg agtgggttcg ggcaacagca tgagatactt gcattgtcat 1704 0 ttttatcgtg tggattttaa ccagggttta taaggctgcg caactgcgcg gcctttttcg 1710 0 ttttgcgggc tgcggttctc ctcttttgat tctccttgtg gccggaccgt ggcccgcaac 1716 0 tgttgaggaa aatcccggaa aggggaggaa taatgacatt taaacattat gatgttgtca 1722 0 gggcggcgtc gccgtcagac cttgcggaaa agctgacaca caaactgaaa gagggctggc 1728 0 agccgtttgg tagtccggtg gccataaccc cttataccct gatgcaggtg attacagcag 1734 0 aaggtgatgt ggtggtcagt ggtgcaactg agccggattg gtactacgtc atcgtactgg 1740 0 ccgggcagtc caatgccatg gcttacggtg aagggcttcc gctgccggat tcatacgatg 1746 0 ctccggatcc gcgcattaaa cagctggcgc gccgcagtac agttacgccg ggtggggctg 1752 0 cctgcagata taacgatatt attccggccg accactgcct gcatgatgtg caggatatga 1758 0 gtacgctgaa tcatccgaag gcagacctga gcaaagggca gtacggctgt gtcggccagg 1764 0 gcttacatat tgccaaaaaa ctgcttccgt atatcccgaa taacgcgggg atcctgctgg 1770 0 taccatgctg tcgtggtggt tcggcattca cccagggcgc ggaggggaca ttcagtgcgg 1776 0 acgcgggggc cagccaggat tcggcgcgct ggggtgtggg taaaccgtta tatcaggacc 1782 0 tgattgcgcg cactaaagct gcattacaga agaacccgaa aaatgtgttg ctggcggtgt 1788 0 gctggatgca gggagagttt gacatgagcg ccgccaccca cgcacagcaa cctgcgctgt 1794 0 ttacagccat gctggcacag tttcgtgctg acctctccgt gtttaacgcg cagtgccatg 1800 0 gtggcagtgc tgcagatgtg ccgtggattt gtggtgacac gacgtattac tggaaaaata 1806 0 cctacggcac ccagtacaac accatttacg gggcgtacaa aaacagggag agtgagggcg 1812 0 tttattttgt gcccttcatg acagacggta acggcgtcaa taccgccact aacgcgccgg 1818 0 cagaagatcc ggatattccg gcatcaggat attacggtgc ggcatcgaga acgaatggaa 1824 0 accaggtatc atcaaaccgc ccgacacatt tcagttcatg ggcgcgcagg agcattattc 1830 0 cggatcgtat ggcaaccgct attctgaacg cagccgggcg cacctcagcc ttcatcagtg 1836 0 gtaaggcacc ggaaatcaaa ccctcgcccg gcggcaacac gccatcgggt ccgtctgcag 1842 0 atacgtccgt tcgcacaatc tccctgctgc cggcagccgg agaggctgct gcgcagggct 1848 0 ggagcattaa ggatggcgga attcagttgt cagatggtgt atttaagatc accaggcaga 1854 0 gcaataaaac ctggtccctg acgcatccgg tggatgacgc aattaccctg ctgacacagg 1860 0 gcggcagact gacctgtaag ttccgcctgt caggcgcact gaccaacaat cagttcgggc 1866 0 tggggattta tctgtatacg gatgctcccg ttcctgatgg tgtggcgatg acgggtaccg 1872 0 gtaatccgtt cctgatgtcg tacttcactc agaccactga cggcagagtg aatctgatgc 1878 0 atcacaggaa agccggaaac acgaagctgg gggagttcgg cgattacggt aacgactggc 1884 0 agacgctgga gctggtgttc accgccggca gtgccacggt tactccgaaa ctgaatggag 1890 0 tggctggccc ggcattccag gttataaaag acagtctgac actgggactg aatgcgctga 1896 0 cgctgacgga tgttacaaaa aatgcagcgt atggcgttga gatagaaagt ctggtgctgg 1902 0 agataaatgc accggcatca tcataaaaag tgagccagtc aaatggaagg tatcgttaaa 1908 0 ctcaccggta gtgtcagtgg gtcgtctgag acgcctgcat gagttatcag agccatcagt 1914 0 agttaactgg tggctttttt attgttgtca gcttccggat aacgggagac ggggtatgta 1920 0 ccagatggaa aaaatcacaa cgggtgtgtc atacaccacg tcagcggtgg ggacgggata 1926 0 ctggttactg cagctgctgg acaaagtctc tccgtcccag tgggtggcga taggcgtgct 1932 0 ggggagtctg ctgtttgggc tgctgacata tctgacgaac ctgtatttca agattaaaga 1938 0 agaccggcgt aaggcggcgc ggggagagta aagtgatgaa gaaaaaatac gaactggttg 1944 0 ttaaagggat aaataattac ccggataaga ttactgttac tgtggcaccg gaaattggtg 1950 0 ggtatccgtc actgttgttg ccagatgtgg cgattagtct tgaccgtact gaaggtgcca 1956 0 cgctggagtt ttacgaagct gaggcgaaaa agcaggcgaa gcagtttttc atggatgttg 1962 0 ctgccgggtt atgtgaaggg gatggtccgt tgccggaaaa gcgccccgta attttagagg 1968 0 cgcaggatgt gttgataacc tacagaggaa aactaccggg aataattacg ggttctctga 1974 0 agactccacc gctggcctga agacttaaca tatccaggga tttgaaatcg ataaaccctg 1980 0 ataaatatcc atgaacgcaa aaatcagata cggcctgtcg gctgccgttc tggcgctgat 1986 0 tggtgcaggg gcgtctgcgc ctgaaatcct cgaccagttt ctggatgaaa aggaaggtaa 1992 0 ccacaccaca gcataccgtg atggtgcggg tatctggacc atctgccgtg gagccacccg 1998 0 gggggatggt aagcctgtta ttcctggcat gaagctgtcg aaggaaaaat gcgaccgggt 2004 0 taacgccatt gagcgtgata aggcgctggc atgggtggag aaaaacatca gagtgccgct 2010 0 gaccgaaccc cagaaagcgg ggatcgcgtc attctgtccg tacaacattg gccccggtaa 2016 0 gtgtttcccg tcgacgtttt acagacggat taatgcagga gatcgaaaag gtgcctgcga 2022 0 agcgattcgc tggtggatta aggacggtgg cagggactgc cgtattcgct caaataactg 2028 0 ttacggtcag gtatcccgtc gtgaccagga gagcgcgctg gcgtgctggg gaatcgacag 2034 0 ataagcagaa tattttgctg aaaaatgagg tttgcttaca tggacggata acacgaaatc 2040 0 ctgcaaattg gcaaaatgta agtgaataaa gtcaaagcag ttgtttaaca ctcaggcacc 2046 0 gtaatgatgc ctttgtcatt tctgcgcatc tcacgcgcat ctcacaacac agaacctttc 2052 0 aggatgaccc ttgaggatac cggtttggct gtcggtgcct ttctgtgggc tggattcctg 2058 0 tgagacaagg ttcatcacta aaaggaaata accgatgaat atgatggccg tgccgtttca 2064 0 cggcaactct ctttatgtag ttaaccataa tggcgaacca tacgttccca tgaaacctgt 2070 0 cgttgcgggg atggggctgg cctggcaatc acagttggct aagttaagac agcgttttgc 2076 0 gtcaactata acggaaatcg ttatggttgc tgaggatggg aaacaacgca atatggtgtc 2082 0 catgccactt cgaaaacttg ccggctggct acaaaccatt aatcccaaca aagtaaaacc 2088 0 cgaaatccgc gataaggtca tccggtatca ggaagagtgc gacgatgttc tttacgagta 2094 0 ctggacgaag ggttttgtcg ttaatccccg taaaatgagc gtgatggaag aactcaacca 2100 0 ggcttgtgct gacatgaaac gggataaaaa cattgccagt gtgtttgcta ccgggctgaa 2106 0 tgagtggaaa caggttaaag ccgcgcatgt atcaaaaatc cgtacgctgg taaatgaagc 2112 0 gaatatgctg attgattttg tcctggctga tacaggcaaa gggaaaataa caaaggcgga 2118 0 ttgatggggt ggctaatgat atcagataaa ctcataacgc tggtgaagag cctctgtgta 2124 0 cttgtcggca tttcattttt agtcatgctg gttgccattt tcttttccac cgcctggcga 2130 0 gtcctgacgt tatcgggact ggtggggtga aagagagatg aaccgtgttc tgtgtgtggt 2136 0 gattattgtc ctggcggttg gctatggtgc gctgtggctg gcaacaaacc attaccgtga 2142 0 caacgcgctc acctacaaag cgcagcgcga taaaaaagcc agagagctgg aacaggcgaa 2148 0 tgccaccatt actgacatgc aggtgcgcca gcgtgatgtt gctgcgctcg atgcaaaata 2154 0 ctcgagggag ttagccgatg cgagagctga aaatgaaact ctgcgtgctg atgttgccgc 2160 0 tggtcgtaag cgcctgcgga tcaacgccac ctgctccggt accgtgcgtg aagccaccgg 2166 0 cacctccggc gtggataatg caaccggccc ccgactggca gacaccgctg aacgggatta 2172 0 tttcatcctc agagaacggt tgatgacaat gcagaagcag ctggaagggg cacaggacta 2178 0 tatccgcact cagtgcctga actaagtttt gctgatgcgc cgtatcgtcg ccgtattcct 2184 0 gcattaacag agaccgcagc ccgacaggga gactcctctg cgagagtgtg cggggataat 2190 0 caaaaacgat acacaccggg gtttaccgcg taaacggagc gcggcgttct cccctcatgg 2196 0 tcgcccgtcc ggtgcgatgg tggaagaaac tggaatctgt tcaataaaaa aactgccgtg 2202 0 ttggagtcac agcagtaatg tactgattgg gtagaagatt attattgtta tgctttattt 2208 0 ttattctata tggctgatta tttcaattcg gaattaatac agctaatgtc tgtgagtttt 2214 0 tataaattca gcaatataaa gaaatagtta tatgaacagc catcgcagag catactgtgt 2220 0 atcattcttt tttatagtca actgacgggc atattttatg tctgctgcca gctcccggcg 2226 0 gcaagattca atgacccacg cagaaaaatt ttctgaacct ttctggtcaa gagcgatgtt 2232 0 aatttgttca atcatctggt ttggaaatcg gatgttgcgg gttgttgttc tgcggggccg 2238 0 gtttttcgat gacattttct ttcctctggt gacaagctat atggcgagga ttttacatgg 2244 0 ctgtgcttcg tacgttaccg ggcagaatca aaactctgaa cacccggcgg ataaatgtcc 2250 0 tgagggggga acagcgtcgt gtcagtggca gtgcccgggt ttccctcaaa cgtcgtatct 2256 0 ggcggaggga tgccggacac tgttgtctct gtagacgcgt ggttgacctt tgtgacagtg 2262 0 aactcgatca ccgcattgca cttcagttcg gtggtggtaa tgaggagacg aacctctgga 2268 0 ccctctgtac tgaatgccat cgccagaagt cagcgagtga agcggcgagt ggtatgcctg 2274 0 atccgacgtt gcctgagctt cctgatggca cgctcagggc cgacggaatc actggcctgt 2280 0 gaccagaccc gggggggatc atccggcgaa aaaaaacgat cgccctggac accgcgcccc 2286 0 ctctcacgca gagaaaaaat tcccgtttca gggcagttaa catgttaact ggctgcccgg 2292 0 gcatttttgc ggtttttatc tttattattc agtttgttgt gcggaaaaaa tgttaacagg 2298 0 ctttttcagc aaatgttaac caggcagcag ttaacatttg cggcatgaga cgccgggaaa 2304 0 aatgggctga accatacccg gctgagtgcg ttctggaccc gggaggaggc tgtgctgaca 2310 0 acgcaaaaac gaaaatttgc gctggcgctc atgtccggga aaaacaaaac agcgtcagcc 2316 0 cttgccgccg gttattcggc gaagacagcc agggttaaag gctcgcagct ggcaaaagat 2322 0 ccggaggtgc ttgcgtttat agcccgtaaa cagtgcgaga cggtggaggt ggatgaggtt 2328 0 cctgtttatc ggcagaaaaa atcagagccg gaggataaac cccgtcgccg tgaggcggct 2334 0 gcaataccac agccggacga aacaaatccg gagatgccac cgcccgtggt gatatctcct 2340 0 ggtattgagt atatggagga cggtcttccc gatccggtga aagcgatggg gcgtcttctg 2346 0 gtggagaaca ttaataccga ccccaggctg gcgctggatg cggcttataa gctggcgcag 2352 0 ttcacgcacc ataaaaaagg ggatgccggt aaaaaatcgg caaaaggtga cgcggcgaaa 2358 0 aaagcggcta accgttttgc ggtgccacca ccaccccgcc tggtggtgaa taatgataat 2364 0 gagggcaacg gatgatacct gtgtggagca cggcctgccc ggactgggca gagcgcctga 2370 0 aaaaggggct gtcgattatt ccggctccga tttatccgga gcaggccgca catgccctgg 2376 0 cgatttttaa acaactgcgg attgtggatg caccgggcag cccgacgttc ggggagtcct 2382 0 gcgcacagtg ggtgtttgac ctggtggcgg ccctgtttgg ctcctacgat gcgcagaccg 2388 0 gtgtacgcca tatcaaggaa gtttttatcc ttatccccaa gaaaaacagc aagtccacgc 2394 0 tggctgccgg gatcatgatg acggcgctgt tactgaactg gcggcaggcg gcgggctaca 2400 0 ccattctggc cccgaccgtg gaggtggcgg ctaacgcctt caaccctgcc agggatatgg 2406 0 tacgacggga cgatgatctg gatgacctct gtcaggtgca gacacatatc cggaccatca 2412 0 cccacagggt gacggacacc accctgaagg tggtggctgc cgatccgaat acggtatccg 2418 0 gtatcaagtc cgtggggacg ctgattgatg aactgtggtt atttggcaag cagtacaaag 2424 0 cggaggacat gttacgtgaa gccataggcg gccttgcctc ccgcccggaa gggtttgtgg 2430 0 tgtatacgac cacccagtcg aatgagccgc cagccggggt gttcagacag aaactgcagt 2436 0 acgcccggga tgtccgtgac ggcaaaattc atgatccgca ctttctgccg gtgatttttg 2442 0 agcatcctcc tgaaatggtg gaaagcgggg ctcacctgct gatggaaaac ctcgccatgg 2448 0 ttaacccgaa tctcggttat tcggtggatg aggcttttct gtaccgggag taccgtaaag 2454 0 cccgggaggc tggtgaggaa gcatttcgtg gcttcatgtc aaaacatgcc aatgtggaaa 2460 0 ttggtcttgc cctgcgttct gaccgctggg cgggtgcgga tttctgggag cagcagggca 2466 0 ggcgcgtcag cctggacgat atcctgcagc gcgctgatgt ggtgacggtg gggattgacg 2472 0 gcgggggcct ggatgatctg ctgggaatgt acgtgattgg ccgtgacagg gaaacccgcg 2478 0 aatggctggg ctggggccat gcctgggcgc atgaaaccgc ggtggtccga cggaagagcg 2484 0 aggcgtcccg gtttcaggat cttgttgcct gtggagatat gaccattgtc cggcgtgtcg 2490 0 gggatgacac ggcggaagtg gcggaatatg tgcgtcgcat tcatgaggct gagttactgg 2496 0 accatatcgg tattgacccg tcaggggtgg ggcagattct ggattcactg gcggaagccg 2502 0 ggatccccga cggaattgtg gtggggataa gccagggctg gaaactgggc ggggccatta 2508 0 aaaccaccga gcgcaaactg gctgaagggg tgctggtgca tggtgaccag cccctgatgg 2514 0 cctggtgtgt cggcaatgcc cgggtggagc ctaaaggtaa cgccattctt atcaccaaac 2520 0 aggccagtgg acggggaaaa attgacccgc tgatggcgct gttcaatgcg gtctccctga 2526 0 tgtcccttaa cccggaaccg aaaaagaaag aatatgcggt ttttttcata taaccctgtt 2532 0 cacactgtaa ccatcatgaa ccgctgcggc ggttttttta ttttcaggag gctgatgtga 2538 0 ctcttaaacg ggcctgttcc ctgctgacgg tgaaatcctt cagtgaggat gaacgggtga 2544 0 tcaccgggat tgcgtcaacg ccttctccgg atcgggatgg tgacatcctg gagccggagg 2550 0 gcgcggagtt tggcagtgcg atcccgtttc tctggcagca tgaccattcc cgcccggtgg 2556 0 ggcagtgtac ggtgcgccgg gtcagcgaag ggctggaaat cacggcaaca ctggtgaagc 2562 0 ccgtaccgga tatgccgtcg caactggctg cccggctgga tgaggtctgg gcggccatta 2568 0 agaccgggct ggtcaggggg ctgtccgtgg gcttccgtcc ccatgaatac acctttctgg 2574 0 acggaggcgg actgcatttt ctgcgctggg aactgatgga ggtgtctgcc gtcaccgtgc 2580 0 ccgcgaatgc ggaatgcacc atccggacca ttaaatctta cgaccgcccg ttttctgccg 2586 0 cgtccggcaa ccggaaaccg gtggtgaaaa tcgcatcttc tgccggcgct gcggcacagt 2592 0 caacaaccgt ttttcataag gaaaagacca taatgaatat tggcgaacag attaaaagtt 2598 0 ttgaaaacaa gcgtgcagcg ctggcagcct cccttgagga ggtcatgacc aaagccgcag 2604 0 aggaagggcg cacgctggat gtggaggagg aagagcatta cgacaacacc gcagcggaaa 2610 0 tccgtcaggt ggatgcgcac ctgaagcgcc tgcgtgaact ggaagccggt aaggccgcca 2616 0 cggcgcagcc ggtgaaacag gccggtaacg ggaatgtggc cgcggtggct tctgcgccgg 2622 0 tgatccgtgt ggagcagaaa ctggataagg ggattggctt cgcccgcttt gccaaatcgc 2628 0 tggctgcggc taaaggcgtc cgatctgaag ccctggaagt ggcccgtcgt cagtatccgg 2634 0 atgacagtcg tctgcatcat gtcctgaaat cggcagtggg cgcggggacc accacggatc 2640 0 cgcagtgggc aggcagcctg tctgaatatc aggaatacgc acaggacttt attgattacc 2646 0 tgcgtccgca gaccattatc gggcgatttg gtcagggcgg gatccctgca cttcgtcagg 2652 0 tgccattcaa tatccgtgtg cacgcccagg tgtccggcgg tgctgccggc tgggtgggtg 2658 0 agggtaaggc aaaacccctg acgaagtttg attttgaatc catcaccttc agtcatgcga 2664 0 aggtgtcggc cattgcggta ctgacggaag aattgatccg tttttccagt ccggctgctg 2670 0 atgcactggt ccgtaatgcg ctggcggaag cggtggtggc gcgtctggat acagactttg 2676 0 tggacccgaa aaaagccgca gtggcagatg tctccccggc gtccatcacc catgatgtga 2682 0 agggcacggc atcaaccggt aacccggatg cggatgcaga ggctgcgttt ggacagtttg 2688 0 tggcagcaaa cctgcagccc accggtgcgg tctggctgat gtccagcacc aatgccctgg 2694 0 cactgtccat gcgtaaaaat gcgctgggtc agaaggaata cccggacatg accctgctgg 2700 0 gtggctcctt ccaggggctg ccggtgattg tctcccagta cgtgggtgac cagctggtgc 2706 0 tggtgaatgc cccggatatt tatctggcgg atgacggcgg cgtggcagtg gatatgtccc 2712 0 gcgaggcatc actggaaatg cagtctgagc cgggcggcga cagtaccacg ccgtccccgg 2718 0 tggagctggt ttccatgttc cagacaggca gcgtggccat ccgtgcggag cgctggatca 2724 0 actggcgtcg tcgccgtacc gcggcggtgg cggtgatcac cggagtgaac tacggcagtg 2730 0 cgtccggcgg ctgagtctga tgaggagggc ggaaggcgcg agcttcccgc agtaacagat 2736 0 ggcaaaaatc cagtatctgc agggcacgca tgatgcccgg gccggggata tccgtgatgt 2742 0 ggcacagccg tgtgcggagg tgctggttcg cctggggaag gcggagtaca tcacagcgcg 2748 0 acgtccggca ggtcagaaaa agaaacgtga tgcggagcat ggcgaatgtg gaaccttttg 2754 0 cggcgaaccc gaaaaaacca gaaatcagga cgtgacgtaa gagaagtggg ctggcggtcc 2760 0 ctgtttcagg cggtggctga gccttttgcc ggtgcctggc agcagggggt gaaagccgat 2766 0 ccggaaaccg ttttgtcctt tcacgcggtg ttttcatgca tttcgctgat atcccaggat 2772 0 attgccaaaa tgcggcttcg cctgatgcag actgatgtac agggaatacg ccgggaaaag 2778 0 cggcagggag atactgcccg tctctgtcgt cgtcctaatg cgcagcagaa tcgcatccag 2784 0 ttttttgaac tgtggctgaa ttccaaattg cgtcacggca atacggtggt gctgaaaatc 2790 0 cgcacccccc gggggcagat caaagaactg cgtattctgg actggaaccg ggttgaacct 2796 0 ctggtggcgg atgacggcga ggtgttctac cgcatcacgc cggaccggaa ctgtgggatc 2802 0 acagagtcgg tgacggtgcc tgcccgggag gtgatccacg accgttttaa ctgttttttt 2808 0 catccgcttg tggggctgcc gccggtgtat gccgcaggac tggccgccat gcaggggcat 2814 0 catattcagg caaattcgac gtattttttc agaaatggcg ggcgaccatc aggcgtgatt 2820 0 gaggtccccg gcagtattac ggaagaaaac gcgaaaaaac tgaaggggaa ctgggacagc 2826 0 ggatatacgg gcgaaaatgc cgggaagacg gccatactga gcaacggggc aaaatacagc 2832 0 cccacgacgt tttcaccggt ggatgcgcag acggtggaac aactgaaaat gacggctgaa 2838 0 attgtctgtt cggtgttccg tgtcccggcc tacaagattg gcgttggcca cccgccttcc 2844 0 agtgacaacg tggaggcgct ggagcagcag tattattccc agtgtctgca gacgctgatt 2850 0 gagtccattg aactgttact ggatgaggcg ctggaaacgg gggaaaacga gagtacagaa 2856 0 tttgatgtca ccacgctgct gagaatggac agtgagcggc gcatgaaaac gctgggggat 2862 0 gcggtgaaaa atacgcttct cacgcccaat gaggcccgta aacgggagaa cctgccgccc 2868 0 ctggccggcg gtgatgcact gtatcttcag cagcagaact acagtctgga ggcgctgtcc 2874 0 cgtcgtgatg cccgtgagga tccgttcgcg tctgccggga aaacagtttc atcacagctg 2880 0 cctgacggcg catctgacgg taataaggca atcagtgaaa cagagcatga tgcggtgaaa 2886 0 gcgatgttca ggggggatac tgagaaaatg acggaacggg aactgtccat tattcgtgca 2892 0 ctgggagaag aattttccac agtgctggcg gatttacagc gcacatttga ggggaagatg 2898 0 gcctcgcagg cacaagcgtt tgaagagaaa ctgacttccc tgtcggcggt attacagaag 2904 0 catgtgacgg tggatgaggt gcgtccggtt ctgcaggcga tggtggatga cgctgtgggg 2910 0 gccattccgg taccgcgtga tggtcgtgat tatgatccgg atgtactgca gcaggcggtg 2916 0 aatgatgcgg tcgcaaatat tccgcagccg gcggacggta aaagtctcac cccggatgat 2922 0 gtgcgtccga tgcttgaaca gatggtgaag gaggctgtaa gccatatccc tgttccgcgt 2928 0 gatggtcgtg actacgatcc ggaagtactg cagaaggcgg tgaatgatgc ggtcgcaaat 2934 0 attccgcagc cggcggacgg taaaagtctc accccggatg atgtgcgtcc gatgcttgaa 2940 0 cagatggtga aggaggcggt aagccatatc cctgttccgc gcgacggtcg tgactatgat 2946 0 ccggaagtac tgcagaaggc ggtgaatgat gcggtcgcaa atattccgca gccggcagac 2952 0 ggtaaaagtc tcaccccgga tgatgtgcgt ccgatgcttg aacagatggt gaaggaggcg 2958 0 gtaagccata ttcctgttcc gcgtgatggt cgtgactacg atccggatgt tctgcagaag 2964 0 gcggttctgg atgcggtgag tgccctgccg gctccgcagg acgggcgtga tgccacggca 2970 0 ctggaaatac tccccgccat tgacgatcaa aaatcctttc cccggggcac gtatgccaca 2976 0 caccagggcg gactctggcg ggcgtatgaa aaaacgcacg ggatgcgggg atgggaatgc 2982 0 ctggttgacg gggtggcgga tattgacgtc agcatgacgg gtgagcggtt gttctctgtg 2988 0 gtggtccggc agagcagtgg ccagcgtacg gaaaaaacat tttccctgcc ggtgatgctc 2994 0 taccgcggtg tgttcagagc cggtgaaacc taccaccccg gcgatacggt gacgtggggg 3000 0 ggctcgctgt ggcactgcaa cagtatgacc gaagataaac ccggagaagc tcattcatca 3006 0 gcctggaccc tggctgcaaa acgtgggcgg gatgcaggag gctgaaaatg acggcattac 3012 0 tgacactgga agagatcaag gcacatctgc gtgtcgacca tgacgcggat gatgacatgc 3018 0 tgatggacaa ggttcgtcag gctaccgccg tgctgctggc ctacattcag ggcagccggg 3024 0 ataaggtgat tcgtgaggac ggtgaactga tcccgggcga ggcattaacc cggatgaagg 3030 0 gggctgccat gcgactgacc gggatgctgt accggaatcc ggatcttgcg gagcgggaag 3036 0 aactgattca gggggagctg ccgttttctg tttccgtgct gatttacgat ttgcgttgtc 3042 0 cgacggtgtt atgaggaggg ggaatggcaa tatctgcagg tcgtctgaca cagatgataa 3048 0 gtgttctgaa cccggtgtta acccgtaacg ctgccggaga aatgacggaa gaatgggtgt 3054 0 catgcgggaa aattcatgcg gatatccggg gcaggagcag ccgggagcgg atgcagtccg 3060 0 gtgcggaaat ggcgcaggcg gaaatccgca tctgggtgcg cggtcagtcc ggtcgggaaa 3066 0 tcacggcagc gtcacgactt catgtgctga gtggtccctg gcgtgaccgg atcctgaacg 3072 0 ttgtcgggct gcccgtgccg gatgcgaccg gcggacgtct ggaaattctc tgtcggctgg 3078 0 gaggggaaaa atgatcgaaa ccctgctgga tttttcgggg ctggaggaca tcagccgcga 3084 0 tttgcagctt ctgagtggtg cagaaaataa ccgggtgctg cgtgaggcaa cccgtgcggg 3090 0 tgcgaatgtg ctgaaagaag aagtggtgtc acgggcaccg gtacgcaggg gaaaactgcg 3096 0 ccgcaatgtg gtggtccttt cccggcgctc ccgcgatggc gggatggaat ccggtgtgca 3102 0 tatccggggt gttaatccgg acaccggtaa cagcgataac accatgaagg cggataaccc 3108 0 gcgcaacgct ttctactggc ggtttgtgga aatggggacc gtgaatatgc caccgcaccc 3114 0 gtttgtgcgc ccggcatttg atgtgcgcag tgaacaggcg gcacaggtgg cgattgcgcg 3120 0 gatgaaccgg gccattgatg aggtactgag acgatgacgg aggcggattt gtatcctcat 3126 0 ctggcgcatc ttgccggcgg gcaggtgtac ccgtatgtgg tccccctgct ggatggcagg 3132 0 ccgtcggtgg cgcttccgtg ggtggttttc agcctgattt catcggtgtc agcggacgtg 3138 0 atgggcgggc aggcggagtc ctcagtgtcg gtgcagatag acgtttatgc cgggactgtg 3144 0 acgcaggcgc gtcagatacg tcaggacgcc cgtgaagcca taatgctgct ggccccggga 3150 0 tccgtcagtg aaatgcagga ctatattccg gaaaaccgct gttaccgtgc aaccctggag 3156 0 tttcaggtca cggtgtaatt ttttcaacag aacccataac ccgccgcgtg cgggtttttt 3162 0 attatcagga ggcagaatgt ctgctttgta tgaacgttca cagctgacgc aggtgatgat 3168 0 ttcatctgcc ccggcgactg ctgaaaccat ggagaaggcg gaatatctgc gcctggactg 3174 0 caccatcaag gaagtccagt tcaccgccgg tcagaaacag gatattgatg tgaccacgct 3180 0 ctgctccaca gagcaggaga acatcaacgg tctgggggcg tcgtctgaga tttccatgtc 3186 0 gggcaatttt tatctgaatc aggcccagaa cgccctgcgt gatgcctatg acaatgacgc 3192 0 gttgtatgcg tttaaggtgc tgtttccgtc cggtaagggc tttaaattcc tggcggaagt 3198 0 gcgccagcac acctggtcat ccggtaccaa cggcgtggtg gctgcaacgt tctcactgcg 3204 0 tctgaaaggc aaaccggtgt cctttgtggt accgctggcg tttgtgaaaa atccggataa 3210 0 gacacttacc gtgaataccg gtgcgctgct gacaatgtca gtcagtgtca acgggggaac 3216 0 gccgccttat aaacacgcct ggaagaagga tggtcagccg gtagagggac agactactga 3222 0 cactttcagt aaagccaata cgcagtcagg tgataagggg gcttatacct gcgaggtaac 3228 0 ggattctgca gaacagccgc agagcattac ctctgatgcg tgtacagtaa cggttaatgg 3234 0 tgcgggcgga taaggcttat ggcaaaagat ctgaaaacac tggcgctggc cagactgtcg 3240 0 gggttccgtc ataaaacggt gaaggtgccg gaatggagaa atgtcagcgt ggtgctgcgg 3246 0 gagccttcgg cagaggcctg gtatctgtgg caggaagtgc tcaatggtga tggagaggat 3252 0 gacgataccc tgtcggtggt ggcgaaaacc cgccgtaacc tggaagcgga tgtgacgctg 3258 0 ttctgcgatg tcctgtgtga tactgacctg caacgggtgt tcactccgga cgaccgtgag 3264 0 caggtgctgg ccgtctatgg tccggtacat gcccggttgc tgcgtcaggc actggaactg 3270 0 atcgctgatg cagagtcggc cagaaaaaag tagcccgccc ggaaattcgc tttctgatgc 3276 0 gacttgcgct ccgtctgggg cgcaccttat ccgaactgcg gcacagcctg agtgcgagcg 3282 0 aggcgatgat gtggatggag ttcgacaggg tatccccgct gggtgatgag cgcggggata 3288 0 tccgtaatgc acagatcgtg aaagcggttt tcggggcaca ggggatgaat gttgcactga 3294 0 aggacgccat gctctgctgg ggcgaggatg aggataagcc ggaggtggat ccgtttgcgg 3300 0 cgctggaaga cgcgctgagc cttgcagcaa tgtcataaat aatgatgaaa acctgctgtg 3306 0 gcaggttttt ttttgcccgg agaaaggtga atggcgacgt tacgtgaact gattatcaaa 3312 0 atttcggcaa attcacagtc attccagtcg gagatccagc gggcgtcccg tatgggcagt 3318 0 gaatattacc ggaccctgca gaatggcggg cgtcaggccg ctgcggcagc ccgggagcag 3324 0 cgacgtgccc tggcagaact gaacagccag ttgacggaaa ttcgcggttc tgctgtcgga 3330 0 atggctggcg catttgccgg tgcctttgcc tccggacacc tgatttcact ggcggatgag 3336 0 tggagttccg taaatgcccg tctgaaacag gcatcacagt catccgatga atttgcgtca 3342 0 tcacagaaag tgctgatgga tatcagccag cggacaggca cggcattttc ggataatgcg 3348 0 gccctgtttg cccgttcggc tgcctcgatg cgtgaatatg gttacagtgc cggtgatgta 3354 0 ctgaaggtga cggaggccat ttcgacaggg ctgaaaatct ccggtgccag tacggcagag 3360 0 gcgggctcgg tgatcaccca gttcagtcag gcgctggcgc agggtgtatt gcgtggtgag 3366 0 gagtttaatt cggtcaatga aagtggtgac cggatcgtac gtgcactggc tgcgggtatg 3372 0 ggcgtggccc gtaaagatct gaaggcaatg gcggatgacg gaaaactgac agcggataaa 3378 0 gtggtccccg cgttaatcag ccagctgggg atattacgtg atgaatatgc ggccatgccg 3384 0 gaaacggttt ccagtagtat cacaaaggtg gaaaacgcct ttatggcctg ggtgggcggt 3390 0 gcgaatgagg ccagcggggt gacaaaaacg ctctccggca tgctgaacgg tgttgccgga 3396 0 cagattgata atgtggcaac agccgtgggc gcgctggttg ccgtcggggt tgcccggtac 3402 0 tttggcaata tggcctccgg agcgatgtct gccacggcag gacttgtgac ggctgcacgt 3408 0 aatgaagttg cactggcgga agcacagttc aggggaacgc agattgccac ggcgcgggca 3414 0 agggcagccg tgtaccgtgc tcagcaggcc gtggcggcag cccgcgggac ggagatgcag 3420 0 attgctgcag aggcccgtct ggcggccaca caggaacgcc tgaacagaaa tattgctgcc 3426 0 agaagcgccg cccagaatgc gctgaacagt acaacggcgg tgggctcacg tctgatgagc 3432 0 ggtgcgctgg ggctggttgg tggcgtaccc ggactggtga tgctgggggc tgcagcatgg 3438 0 tacacgctgt accagaatca ggagcaggcc agggagtctg cgcgccagta tgcactgacg 3444 0 atagatgaaa tcgcgcataa aacgccgtca atgtctttgc ctgaagcctc agataatgaa 3450 0 ggacgaacac gggcggcgct gacagagcag aaccggctga ttgatgaaca ggccagtcgg 3456 0 gtgaaatccc tgcaggaaaa agcgcagtcc attcaggatg tgcttgccgg gctggaagac 3462 0 cgtcgtgtgg cgttaattcg tcagcaggcg gcagagcaga ataaggtgta ccagtccatg 3468 0 ctggttatga acggtcagca tacggaattc aaccgtctgc tggggctggg gaatgaactg 3474 0 cttcagcagc gtcagggact ggtgaatgta ccgttacggc tgccgcaggc caccctggat 3480 0 gataaacagc agagtgccct gacaaaaaca gagcgtgagc tggccctgtc cagactgaaa 3486 0 ggggaagaaa aagagcgtgt ccgactgggg tatgcggcgg atgacctcgg ttttgtgggt 3492 0 gatccgtatc aggaggcgag acaacgttat atcagtaatg ccctggaagc ctggcgcaat 3498 0 aacgaggcga ataaacccaa atcccggggt ggaaaatcag agacggaaaa agcggaagac 3504 0 agtttttccc ggctgctgaa gcagcagaaa gagcaactgg cactggtggg gcagaataca 3510 0 gagctggcga agctgaaata ccagacagcg ctgggtgaac tgaaaaccct gacggagatg 3516 0 cagaagcagg aactgctgcg taacgcgacc ctgattgacc agcaaaaaat ccgggaacag 3522 0 ttgcgatccc gggaagagac actgaagaat gagaatgcgg ctgcgcgtgc gtcgaatgat 3528 0 gctgaactgc tggggtacgg gcagggggag cgagccagag aacgcatgcg ggagttgcag 3534 0 cagatccgcg acagcttccg ccagaaggat gcggaccttc agtctcagta tcagaccggg 3540 0 gatatcagtg aggattttta cagacaggct ctggcacaga acgcgcagta tctgagcgaa 3546 0 cgccttaagg accaggcagt cttttatgcc gaatcggatg tgcagcgtgc ggactggcag 3552 0 aaagggctgc aggagggatt cagtaactgg gtggataatg cgtccgatta cgcctcacag 3558 0 gcagcacagc tggcgacgga gggtatctca gggatggtga ataacatcac ggagatgctg 3564 0 aacggaaata aagtggaatg gcgcagctgg gcctcatcag tgctgcagga aatatcaaaa 3570 0 gttcttatga atgccgcgat tgtcaacgga attaagacgg cggcaaacgg tatgtccggt 3576 0 gcgggaggat ttctcggcag cattggtgac tggctgggcg gagcggtggc caatgcaaaa 3582 0 ggcggcgtgt atacctcggc aaacctgagc gcgtacagca acagcattgt ggacacgccc 3588 0 acgtactttg cgtttgcaaa aggggccggg ctgatggggg aagccggacc tgaagctatt 3594 0 atgcccctga cccgggcggc ggatggctcg ctgggcgtac gcgccgtggg cagtatgaac 3600 0 ggcagtgctg gtctggtgta ttccccggtc taccacatcg ccattcagaa tgacggggct 3606 0 aacggacaga tagggccgga ggcggcaggc agtcttgtgc agctgattga ccagcgggtg 3612 0 caggcggtga tgctgtccat gcgacgtgac ggaggaatgc tgagtggctg agataaaaac 3618 0 gctgcatctg gtcccgcgtg aagggatgca ggtgagtgag aagccgtcgg tggtgagggt 3624 0 gcggtttggt gacggttatg aacagcgccg ccccacaggg ctgaatcctc aactgaagac 3630 0 gtttcaggcg gtgttccggg tgacggatga gtcaacccgg cgctggctgg atgaattttt 3636 0 atcctggcat ggtggttacc gtgccttttt gtggcgaccg ccgaaacata accggacggt 3642 0 gagggttgtg tgccgggagt ggagcgtcac ggataacgcc cggtacagtg atttcagctg 3648 0 tacgattgag caggtggtga actgatgcag gacattcatg aagaaagtct gaacgagtcg 3654 0 gttaaatcag agcagtcacc gcgggtggtg ctctgggaaa ttgacctgac ggtgcagggc 3660 0 ggtgagcggt attttttctg taatgagctg aatgaaaaag gggaggcggt cacctggcag 3666 0 gggcgggaat atcaggcata cccgattgac ggcagcggtt ttgagatgaa cgggaagggc 3672 0 agcagtgccc gcccgtcact gacggtgtcc aatctgttcg gtctggtcac cggaatggcg 3678 0 gaggacctgc agagcctggt gggggccacg gtggtccgcc gccgggtgta tgcccgtttt 3684 0 ctggatgcgg tgaattttgt ggcgggcggt cgtggttatc gggcggcaga ggtaaaaaga 3690 0 ataaaaaaat cccgcagagt tgcggggaca gacaaagatt aacgttaagg agttattttt 3696 0 gtttctggtg ctcgggcaaa aaaacattaa cgcagagaaa ttattagcac cacagtcagt 3702 0 ttgtgaaaat gtgaagatat tcagaagttt tattcagtca tgatacaggc atcctccggg 3708 0 atgcctgttg tttttgtgcg taacagttat cacagtaaag ggtgagacaa tgggcaaagg 3714 0 tggcggcaag gcgcacacgc cggtagaggc aaaggacaat cttaagtcca cgcagatgat 3720 0 gagcgtgatt gatgccattg gtgaagggcc gattgaaggt ccggtgaagg ggctgcagag 3726 0 tatcctggtg aacaaaaccc cgctgacgga cacggacggt aatcctgtga tacatggtgt 3732 0 gacagcggtc tggcgcgccg gggagcagga gcagacacca cctgaaggct ttgagtcctc 3738 0 cggggcggaa accgcactgg gcgtggaagt gacgaaggca aagccggtga cgcgcaccat 3744 0 tacgtccgcg aacattgacc gcctgcgggt caccttcggg gtgcagtcac tgttggagac 3750 0 cacctcaaag ggcgaccgta atcactcttc tgtccgactg ctgattcagt tgcagcgtaa 3756 0 cggtaactgg gtgacggaaa aggatgtcac cattaacggc aagaccacct cgcagttcct 3762 0 ggcgtcggtg attctggata atctgccgcc ccggcccttt aacatccgga tggtcaggga 3768 0 gacggcggac agcaccacgg accagctgca gaacagaacg ctgtggtcgt catacaccga 3774 0 aatcatcgat gtgaaacagt gctacccgaa cacggccatt gtggggctgc aggtggatgc 3780 0 ggagcagttt ggcggtcagc agatgacggt gaactaccat atccgcggtc gcatcatcca 3786 0 ggtgccgtca aactatgacc cggaaaaacg cacgtacagc ggcatctggg acggcagcct 3792 0 gaaaccggca tacagcaaca acccggcctg gtgcctgtgg gacatgctga ctcacccgcg 3798 0 ctacggcatg ggaaaacgcc tgggggcggc ggatgtggac aagtgggcgc tgtatgccat 3804 0 tgcgcagtac tgcgaccaga cggtcccgga tggtttcggg ggcacagagc cgcggatgac 3810 0 tttcaatgcg tacctgtcac aacagcgtaa ggcgtgggac gttctcagtg atttctgctc 3816 0 ggcgatgcgc tgtatgccgg tatggaacgg gcagacgctg acgtttgtgc aggaccgtcc 3822 0 gtcagatgtg gtgtggccct acaccagcag tgatgtggtg gtggatgata acggcgtggg 3828 0 gtttcgctac agcttcagcg ccctgaagga ccgccacacg gcggtggagg tgaattacac 3834 0 cgacccgcag aacggctggc agacctccac ggaactggtg gaagacccgg aagccatact 3840 0 gcgctacgga cgcaacctgc tgaagatgga tgcgttcggc tgcaccagtc gcggtcaggc 3846 0 ccaccgtgcc gggctgtggg tgataaagac cggactgctg gaaacgcaga cggtggattt 3852 0 cacgctcggg tcacaggggc tgcgtcacac acccggtgac attattgaaa tctgtgataa 3858 0 cgactatgcc gggaccatga ccggcggacg tatcctgtcc atcgatgccg ccagccgcac 3864 0 cctgacactg gaccgtgagg tgaccctgcc ggagaccggt gccgccacgg tgaacctgat 3870 0 taacggcagc ggtaagccgg tgagcgtggc catcactgca caccccgcgc cggaccggat 3876 0 acaggtcagc accctgccgg atggcgtgga gacatacggt gtgtgggggc tctccctgcc 3882 0 gtcactgcgc cgtcgcctgt tccgctgtgt ctccgtccgg gaaaacacgg acggcacctt 3888 0 tgccatcacg gcggtgcagc acgtaccgga aaaagaagcc atcgtggata acggtgcccg 3894 0 ctttgagccg cagtcaggca ccctgaacag cgtcatccct ccggcagtgc agcacctgac 3900 0 ggtggaggtg agcgcagctg acggtcagta tctggcgcag gcgaaatggg acacgccgaa 3906 0 ggtggtgaag ggcgtgagct ttatgcttcg cctgaccgtg gccgcggatg acggcagtga 3912 0 gcggctggtc agcacggccc ggacgacgga aaccacatac cgcttcacgc aactggcgcc 3918 0 ggggaactac aggctgacag tccgggcggt aaatgcgtgg gggcagcagg gcgatccggc 3924 0 gtcggtatcg ttccggattg ccgcaccggc agcgccgtca cagattgagc tgacaccggg 3930 0 ctattttcag ataacagcgg tcccgcgtct tgcggtgtat gacccgacgg tacagtttga 3936 0 gttctggttt tcggaaacgc ggattaccga tatcaggcag gttgaaacca cagcccgcta 3942 0 ccttggcacg gggctgtact ggatagccgc cagtatcaat atcaaaccgg gccatgatta 3948 0 ttacttttat atccgcagtg tgaacaccgt tggcaaatcg gcatttgtgg aggctgttgg 3954 0 ccagccgagt gatgatgcat ccggctatct ggattttttc aaaggagaga tagggaaaac 3960 0 ccatctggct caggagttgt ggactcagat tgataacggt cagcttgcgc ctgacctggc 3966 0 ggaaatcaga acgtccatca cggatgtcag taatgaaatc acgcagaccg tcaataagaa 3972 0 actggaagac cagagtgcag cgatccagca gatacagaag gttcaggttg atacaaataa 3978 0 taacctgaac agcatgtggg cagtgaagct gcagcagatg caggacggac gcctttatat 3984 0 tgcgggtatc ggtgccggta ttgagaacac ctctgacggc atgcagagtc aggtgctgct 3990 0 ggcggcagac aggattgcga tgattaatcc tgcgaatggc aacacaaagc cgatgtttgt 3996 0 tggtcagggc gatcagatat tcatgaatga agtgttcctg aaatatctga cggctcccac 4002 0 cattaccagc ggcggtaatc ctccggcatt ttccctgaca ccggacgggc ggctgacggc 4008 0 gaaaaatgcc gatatcagcg gtaacgtgaa tgcgaactcc gggacgctca acaacgtcac 4014 0 gattaacgag aactgtcggg ttctgggaaa attgtccgcg aaccagattg aaggcgatct 4020 0 cgttaaaaca gtgggcaaag ctttcccccg ggactcccgt gcaccggagc ggtggccatc 4026 0 aggaaccatt accgtcaggg tttatgacga tcagccgttt gaccggcaga ttgttattcc 4032 0 ggcggtggca ttcagcggcg ctaaacatga gaaagagcat actgatattt actcctcatg 4038 0 ccgtctgata gtgcggaaaa acggtgctga aatttataac cgtaccgcgc tggataatac 4044 0 gctgatttac agtggtgtta ttgatatgcc tgccggtcac ggtcacatga cactggagtt 4050 0 ttcggtgtca gcatggctgg taaataactg gtatcccaca gcaagtatca gcgatttgct 4056 0 ggttgtggtg atgaagaaag ccactgcagg catcacgatt agctgaattt tataacccag 4062 0 atacgggcgc cagaaatggc gcctttttta ttgcagaaaa gcgagaggta attatgcgta 4068 0 aattatgtgc tgttattttg tccgcagtag tctggcaggt cgccgctgct acgccagcga 4074 0 gtgcagcaga acatcagtcc acgctgagcg cggggtatct ccatgcctcg acgaacgttc 4080 0 ccggtagtga tgatctgaac gggattaacg tgaaataccg ttatgagttt atggacgcgc 4086 0 tggggctgat tacgtccttc agttatgcca atgctgagga tgagcaaaaa acgcgctaca 4092 0 gcgatacccg ctggcatgaa gattccgtgc gtaaccgctg gttcagcgtg atggcggggc 4098 0 cgtctgtacg cgtgaatgaa tggttcagcg cgtatgcgat ggcgggtgtg gcttacagcc 4104 0 gtgtgtcgac tttctacggg gattatctcc gcgtaactga caacaagggg aaaacgcacg 4110 0 atgtgctgac cggaagtgat gacggtcgcc acagcaacac gtctctggcg tggggggctg 4116 0 gcgtgcagtt taacccgacc gaatccgtga ccattgacct tgcttatgaa ggttccggta 4122 0 gtggcgactg gcgatcggat gcatttattg ttggtatcgg ataccgtttc tgacaacaga 4128 0 cgccgattta tcttctgtaa atattgttat gatacgcagg ttcatccacc ttatggggtg 4134 0 aactgcgttt gaggaaacgt aaagttacac tgtcctgaag cccgtggcgt cactgctgcg 4140 0 ggcttttttt attggtggaa aagtatgaca gtaaaaattt ctggcgtgct taaagatggc 4146 0 acaggaaaac cagtacagaa ctgcaccatt gtgctgaagg ccagacgaac cagcagcacg 4152 0 gtggtggtga acacggtggc ctctgaaaat ccggatgaag ccggacgtta cagcatggat 4158 0 gttgagtacg gtcagtacag cgtcattctg ttggtggagg gatttcctcc gtcacatgcc 4164 0 gggaccatca ccgtgtatga agattctcaa cccggtacgc tgaatgattt tctcggtgcc 4170 0 atgtcggagg atgacgtccg gccggaggca ctgcgtcgtt ttgaactgat ggtggaagaa 4176 0 gcggcgcgtc acgctgagga ggcgaagaag aatgccggag aggcggagac gtccgcgagg 4182 0 aatgccggca tatcagccag tcaggcagaa gagaacgctg caaatgctga cacttcagca 4188 0 ggggatgcat cggagtcagc ccggcaggcg gcagaaagtg cagccgctgc aaagcagtca 4194 0 gaggaggcgt cctcgtcctc ggcctctgcg gccgctcaaa aagccagtga gtcattacaa 4200 0 agtgcaacag atgctgagtt gtcaaaaaag acggcagaaa gtgcagccgg taatgcagcc 4206 0 agggatgcaa cgaccgcagc agaaaaagcc cgggagtcag cagaaagcgc acagtcagcg 4212 0 gaacaaagca ggatagcggc ggaagaagcc gtaaaccgaa tccccaccgt ggtggggcct 4218 0 cccgggccaa agggggaacc ggggcccgcg ggtcctcagg ggccgaaggg agataaagga 4224 0 gagcgtggag acaccggccc ggcaggggca accggcgaac ggggaccggc aggtgatgct 4230 0 ggtccggcag gcccgcaggg gccgaaaggt gacaggggag agcggggaga gaccggtctg 4236 0 acgggaaatg caggtccaca gggtccaaag ggagacaccg gggcagcagg cccggcaggc 4242 0 ccacagggac cgaaaggaga aacaggtgcg gctggcccgg tgggggcaac cggacctcag 4248 0 ggaccgaagg gcgacccggg ggagacacaa atccgttttc gtctggggcc ggcgagcatt 4254 0 attgagacaa acagccatgg ctggttcccg ggtacagatg gtgcgctcat caccggactg 4260 0 acctttcttg cccccaaaga taccacacgg gttcagggtt tttttcagca tttgcaggtc 4266 0 aggtttggtg acgggccgtg gcaggatgtt aaggggcttg atgaagtggg cagtgataca 4272 0 ggcagaacag gagaatgaca tgaacatact aaaaaaactt atgcagcgtc tgtgcgggca 4278 0 cggaaagcat gatgaccgtg aagacgggga gttacttaca gcacaactgc gtctggggcc 4284 0 ggcagacatc ctggagtccg atgagaatgg tattattccg gagcaggaca gggtaatcac 4290 0 gcaggtggtg atactggatg cggataaaaa gcagatacag tgcgtggtaa gaccgctgca 4296 0 aatcctgcgt gctgacggga cgtgggaaaa tattggcggg atgaagtaac ccgacagctt 4302 0 cacaaaaccg gagtccggct ccggtttttg ttgtcatgta aggcagatgt ttgttaaagc 4308 0 tatttaagtc tggagtttaa attaaaatag ggagttttat aatgccgtta aattcggaga 4314 0 ttagatcaag ctcattttta atggattgaa tgtccttcga gctcaagtag catctagcgg 4320 0 tcgaggggag tttacattag gtaatgagac tgtcagcatt gtatttaatg aaaccgatgg 4326 0 gcgttttcta tccagcggca gtagtggggg attgcttact gagttattcc tttatgggtt 4332 0 taataacggc cctgaagctc ttcgcgatag gatgctcagt atgctttcgg actcaggtga 4338 0 agcacaatcg caagagagta ttcaggacaa aatatctcaa tgtaagtttc ctgttagttc 4344 0 aggaaatttc cagtgcccgc cagagtctat tcagtgtcca attacactag agagacccga 4350 0 agaaggagtg tttgtcaaaa attcagatag ttcggcagta tgctgcttat ttgattttga 4356 0 tgcattttct cgtttagcta gtgaaggctc atatcatcca ctgacccgag aaccaataac 4362 0 ggcatcaatg attataagtc ctgataaatg tgtttatgat cctatcaagg gaaacttcat 4368 0 tataaaagat agttaaaata tttttctctg agagagtatt ggctgtcagt aatttgtaaa 4374 0 aaaacgccgc agacatccag aatataagaa ggtgtctgtg gttggcaggt ttcagatgac 4380 0 ttgaaggcgt ctttatgtaa atgcattttt ctgtggagat gttgtcggaa aatattggat 4386 0 taaaaacata atccaagtca aatagtaagt ttgttttttt tgagattagg tgtgtgtatt 4392 0 tagaattttt atgatgtgtt tattttgtgg ggtattttag aaaaaatata ttaatcctta 4398 0 ttaataatag ctgccatcca tttcagctat tattttaaaa taaacaagtt aaagcttaga 4404 0 ctcttgtttc ttggattata tcaaagatat caacatgatt tgatggatta tgatgtggta 4410 0 agccattgct ttcgatatcg attaccacat cctctggatt tggatgccgc tgtccaacag 4416 0 ggataccttc ttccattgcg cgtatatcag cacctgtggc atgttcaata tctgctttat 4422 0 tggggaaaat agctccttct cttgcgtgcc accatatacg aggatagtca gtgaatctag 4428 0 ctacttcaaa ctcggccttg tttaaatcgg cagcccccag tgtcgcacca gcccaccata 4434 0 aaatagtgtc tggctttaat ccaggggtat tatactgtat ggcatgccct gctgcttgcc 4440 0 caaccattgc accgatatga ggacttaaca ttggatctgt actagcaaat ctggatactg 4446 0 caaatccccc taaagcacca agcgcatttg cggcagcatt ggtaagaacg gcatatttag 4452 0 tattagggtt atctaaatcc cacttgaaat gtgcgccaaa ctccagccct agagttgcct 4458 0 gtaatggaga tgcaccatat ttaaaatctg cttctcccgg tctgataacc cactcctccg 4464 0 tgtaatttgc tttcggccca tcaggagtaa gtggtgtttc tccaacaagc ttccatccat 4470 0 tttcagtttt gactatagga agttctacac catgattacg aaccacttga gctgttaatc 4476 0 caaaccatgg tattgggtct tttggctcgg tggttaccgt cgaagtagtg gctgatgttc 4482 0 cagtcgatgc aatagtcgac actgcagtgg ttgatatatt actgttgctt aatgcatttt 4488 0 ttaacgggcc aggaaggtct ttaaaattaa aacctatttc atcatgcaga gggaatatct 4494 0 gtaaaaaata attacctgat gtaggatgaa tatctggttt tacaatgttt agctggacac 4500 0 catatttacc agagatgcct gaaacggaac taggtatctc taatgccatt tgggtaacat 4506 0 tgaataaacc aaacatatcc aatgtttttt ttcctatgga tccttcttca aggtgaggag 4512 0 ctatatattc gtctagccct gagagcagac ctttatcttt tatcaagctc agtagagctg 4518 0 ttgtttcacc gcattccggt gcatgttgct gtatatcatc tggaatatta acaacaaatc 4524 0 cagcttggca tcctagaggt aattcggatt gcggtatttg tgtagagggt atttgttctg 4530 0 tttgatgatg ttgattgttt tgtgaggtga ttccagattg tatggtcggt tgaatgttca 4536 0 taataaatcc ttattacatg tttatatcca ttaataatat caatccattg atactattag 4542 0 tgtcacatat ccgatgtgga cagctttaat atataactgt ttgaatgctt gattgatgtg 4548 0 acttagatct caaaattaag ttgttaaatt taccagttta tcgcttgaac acttaaaata 4554 0 aattataaat gtttctgtta ttgtttttta tagtttaaat tattgttggt tgtataagct 4560 0 gattacattt ttactctaag tgttataaat attttatact gatattagtc ttattatata 4566 0 tttttttaat gaaaatgagc ataaaactaa gacatataat gcttggcagc tttatgctct 4572 0 tctgattggc tgtatgtttg atgacaaaaa attagcgcaa gaggacaaaa aatcaccttg 4578 0 cgctaatgct ctgtctcagg tcactaatca catctaactc attgattaat tgtgactcta 4584 0 aatgtagtgt tttgtcgcgt tttgcagtct atcatttaat caattgtata aataacataa 4590 0 tgatttttaa tgtgtttttg tgattttatc ctccttctga catggaagtt gttcgttcaa 4596 0 aaatcttatt aaatatcaag ttgttaaatc tggtaagtca ttattggtca aaataaaatc 4602 0 attatccgat ttcaattttg tcccactccc gcccgcgact gtccctataa tgcgccgcca 4608 0 ttgaatcaga tttatgtcca agaagacgtt gtgcaaactt gtagccaatc tggttccgat 4614 0 atagcctcgc ggacagacta cgtagttcat gaaatgtcgg tgggtctcca tcaaacgaga 4620 0 tcccggatgc atttcgcgcc tttgttaaat accgtgatac tgtggctgga gaaagtggtt 4626 0 cgtgataggt tgatgcgatt attgtttcac tgctgctggc ctccctgcat ttctgtagtg 4632 0 tatcaaccag tgagatgtcg agtgcgtcaa tggttagagc cagcggaatg gcaattttgg 4638 0 ctcctgtttt actctgtcca atgtgaagat gaccatcgtt tatgtctgac cacttcattc 4644 0 tgcacaaatc gcccactctc tgccctgtaa cgacagctaa atccattgac agcctcagcc 4650 0 agatggggag gtgctcagca gcatggtaaa tagcgacata ctcattagct gtcagccttg 4656 0 agcgccttac ttctgacttt gctgcacggg ttgttgttac tggattcgtt gccacatgcc 4662 0 cctcggctat tgcccctcga aaaacgtcaa caagggttga cctgattact cttgcggaaa 4668 0 ccgctttacc ttctgcgacg taggtgttta gcattgctgc cacctctttc gttgatatgt 4674 0 cagtgagcgg tttgtccggc aattttcttc gaattgccct gattttgctg gcgtagtcga 4680 0 gtaatgtttt cggcttgctc cccctctagc tgaggattgt ttcatatcga tcaagccacg 4686 0 tatgaagagt gattgagtca gtgcctttaa ccctgtccag caatgattcg tgcccacttt 4692 0 cgctgaaaag ctcaatgttg gtgtgaatgc ttctgaaatt gctactcttc tgtctcttcc 4698 0 cagcccgaac tcttttttcg tcctcgggtc agtgtgtagt aagaccgctg caaatcctgc 4704 0 gtgctgacgg gaagtgggaa aatattggcg aaatgaagta acccgatagc ttcacaaaaa 4710 0 ccggagtccg gctccggttt ttgttgtcat gtatggggga tgtctgttag gaataattag 4716 0 ataggtttat tttgaaggtt gaaatgtatg ttatcgccct cttctataaa tttgggatgt 4722 0 tcatggaatt ctttaaccag aaacctgact tcgcctgata atcgtgtttt atcctctgta 4728 0 agggatgctg ctgttcactc tgatagcggg acgcaagtaa cggttggcaa cagaacatat 4734 0 cgtgttgtgg tcactgataa taagttttgc gttacaagag aaagtcatag tggttgtttt 4740 0 actaatctgt tgcacaggtt gggatggcct aagggagaga ttagcagaaa aattgaggct 4746 0 atgctgaata catcgccagt gagcacgact atagaaagag gctctgttca ttcgaacaga 4752 0 cctgatttac ctccagtgga ttatgcgcag ccggagttac ctccagcgga ttatactcaa 4758 0 tcagagttgc cgagggttag caacaataaa tcacccgtgc caggtaatgt tattggtaaa 4764 0 ggtggtaatg ctgtcgtgta tgaagatatg gaagatacaa caaaagtgtt gaagatgttt 4770 0 actatatctc aaagccatga agaggtgaca agcgaagttc gttgtttcaa tcagtattat 4776 0 ggttccggga gtgcagagaa aatatataat gataatggaa atgttattgg tattagaatg 4782 0 aataaaataa atggggaatc tcttttggat attccatcat taccagcaca agctgaacag 4788 0 gctatttacg atatgtttga cagactggag aaaaaaggaa ttctttttgt tgatacaaca 4794 0 gaaacaaatg ttttatatga tcgtatgaga aatgaattta atccaataga tatatcatct 4800 0 tataatgttt ctgatatttc atggagtgaa catcaagtca tgcaatctta tcacggagga 4806 0 aagctggatc ttattagtgt agtattaagt aagatataat atttttatcc agatatatta 4812 0 gttgcaataa tatttatgga tttatttgtt aagggggttt tgatatgtta ccaacaagtg 4818 0 gttcttcagc aaatctttat tcatggatgt atgtatcagg aagaggtaac ccttcgactc 4824 0 cggaatcagt aagtgagctt aatcataatc actttctttc tcctgaatta caagataaac 4830 0 ttgatgttat ggtctctata tattcatgtg ccagaaataa taatgagctt gaggaaattt 4836 0 ttcaagagct aagtgctttt gtaagtgggc tgatggataa gagaaatagt gtatttgagg 4842 0 tgagaaatga aaatactgat gaggttgtcg gagcgctgag ggcgggaatg acgatagagg 4848 0 acagggatag ttatatcagg gatctttttt ttctgcattc attgaaagta aaaattgagg 4854 0 aaagtagaca aggcaaagaa gattcgaaat gtaaagttta taatctgcta tgtccgcatc 4860 0 actcttcaga gctatatggt gatctacgag caatgaaatg cctcgtggaa ggatgcagtg 4866 0 atgattttaa tccttttgat attattaggg taccagatct tacttacaac aaaggatctt 4872 0 tacaatgtgg atgattagag gcctgtgagc ctgtttagga ttctgtgtaa atgccttttc 4878 0 ttaaaagtga ccgtcaagac ggtcaccaaa ctcgataata aagcggctca ttgccattcg 4884 0 ccagtccctt aacggcattg tccatttctg tgacgcggcc tggattgcca gccacaccac 4890 0 tttttttact gactcgtccg tcgggaacac cttgcgtttc ctgatggcat gccggatcac 4896 0 actgttcagc gactcgatgg cgttcgttgt gtagatcact ttgcggatat ctgccggata 4902 0 agcgaaaaac gtcgccaagt tagtccagtt tgacagctag caccggctta tctgcggata 4908 0 gcggcagtcc caggccgcag caaacgcttc cagtgcctgc tggcctgcct cttctgtggg 4914 0 aggctaatcg ctttcaggtc gcgagtgacg gctttgtatt ccttccatga cacgaagcgc 4920 0 atgctgttgc gcaccatatg cacgatgcat aactggatgc gggcctccgg gaattctttc 4926 0 aggccataca cacaggcgat gaggatatcg ttcagaccgc ggtttttcag ttcagtcagc 4932 0 acattgaacc agaaattcgc cccttcattt tcggccagcc gcatccccag gagctctttc 4938 0 tgacctgcga tattgatgcc cagtgctagg aacattttta tgataaaaaa ttagtgcaag 4944 0 aagacaaaga atcgccttgc gctaatgctc tgaaacaggt cactaatatc atctaaatag 4950 0 ttgactcata gtgacagcat gtgttgtgtc ttgcagtatt atatagccta ttatttagat 4956 0 tgaagccatc ataatctatt gatgttaatg gttttttatt gtttgttgtt cggcttttta 4962 0 tactaatttg agcgaaacaa aaagataaaa agttgttttt cggtaagcgt acagcgaggg 4968 0 ccgtattgac ggggatgtgt tattcagctg gcagtgctat gcgccacgga agcagttcgc 4974 0 tgacccggtt gaccggccag tctgctatga cgccaagcac atggcgaagg tagctttctg 4980 0 gatccacgtc attcagtttg cacgtcccga tcaggctgta cagtagcgct ccccgctcac 4986 0 caccatgatc agagccgaag aacaggaagt ttttacgacc cagactgacc gcccgcaggg 4992 0 cattttcagc gatgttgttg tcgatttcca cccagccatc gttcgcatag tacgtcagtg 4998 0 ccggccactg gttaagtgcg tacgcgaacg ccttcgccaa ctctgagtgt cgcgacaggg 5004 0 tcttcatctt ttcacgcaac cagctttcca gggatttcaa caacggtttc gtttttcgct 5010 0 gacgttcagc aagccgctgc tctgccggca ttccccttat atccgcctct atggcgtaca 5016 0 actgaccgat ctgctccagg gcttcttccg tcagtgctga cgggatgcgg acgtgcacat 5022 0 cgtggatctt tcggcgggca tgagcccagc aggcagcttc cgttatccca ccattgcgat 5028 0 acagctcgtt gaacccggcg tacgcatccg cttgcagcac accgctgaag caggcaagat 5034 0 gagtctgcgg atggatgcct tttctgtccg ggctgtaagc gaaccacact gcaggtgcca 5040 0 acgctgaccc tgcattgcgg tcatcacgaa catacgccca caaccgcccg gtcttcgtct 5046 0 tcttattacc cggcagcagt acctggaccg gggtatcatc ggcatggagt ttgccgtcag 5052 0 tcatgacata gccatgaagc gcctcttcca gcggagacag cagccggcag catgcatcca 5058 0 cccagcccga cagcagtgaa cgcctcagct ccacaccttg ccggccgtat atttctgact 5064 0 ggcgatacag cggggtgtgc tctgcatact tcgaggtcag cacgcgggcc agcagccccg 5070 0 gtccggcgat accccgctcg atgggccgcg aaggtgcagg tgcctgcacg atggcatcgc 5076 0 actgagtaca ggcatgtttt tcccgtaccg tccggataac ccggaaggcg ctacgcatca 5082 0 actccagctg ttcggcggta tcctcgccca gatagctcag tgaaccgccg cagttcgggc 5088 0 agcacggcgc cgcaggcaac agtcgctttt cgtcacgggg tagtgattca gggaacggct 5094 0 tacgggtgcg ggtctgacgc aacggacgct gtactgccgg gtcatacacc ctaccagtca 5100 0 gcgtatcgct ctctttctga agccggttca gatcggcttc catttgtgcg atacggcggg 5106 0 agactttttc ggaacgactg ccgaagttca tccggcggag tttatccagc tgcgcctgca 5112 0 gatggtctat ttcgcgctcc cggttgctca gcttttcctg cagggcgtgg atcagcgctt 5118 0 cctgttcggc caggcgctgt ttcagcagga agatgtcgtc agaagagatg tcgttcataa 5124 0 gcccgtattt taccgggctt attctgtgac aaccaggata aagagattta cagcatggtc 5130 0 agggaggtca gcagccgctt aggctgtcgc cagtcgatac cttccagcag catcgccagc 5136 0 tgcgcctgcg taaggaacac tttgccatca cgggctgacg gccaggcgaa gcgcccacgc 5142 0 tccagccgtt tggtcaggag gcacagtccg tcaccggtgg accacagcag tttaacctga 5148 0 ctgccgctgc ggccccggaa aatgaaaaca tggccggaca tgggatcgtc tttcagcgcc 5154 0 gtttgtactt tcgcagccag gccgttgaag ccatttctca tatcggtgat accggcaacc 5160 0 agccaaattt tggtcccgga aggtaacggg atcatcgctt cagttcctgt atcagcagag 5166 0 tcaggagctt ttcgctgaca ttgccattga agcggagcgt cccgtgccgg aacgttacct 5172 0 cacagctgat actgagggtt tccgggtcct ctgcgagcga ttctggctgt tcggcagctg 5178 0 catcgagagt cacaggaagt agctgggggc tctctgaaga aggtaatagc agctttccct 5184 0 cgcgccattg ttgtcgccat ttgaacaaca gatttgcgtt aatgccattt tcaagagcaa 5190 0 gttttgagat ggatatcccg ggttcacagg aggcagcaac gagctgctgt ttaaattcgg 5196 0 gaggataatt agggcagcct tttcgcctgc cgggagtcac atttttctgc atatctgata 5202 0 ctttggttcc cactacttat ttggtggaca ccactttgtc taattcgtca gattctgacc 5208 0 agacggttca ggctgtacgc ttacgttttt cgtgtcttta agtgatacca gatggtattg 5214 0 cgctaaatgt accaatgggt ataccaagag cactaaaaac aaaggggcaa ccactttgta 5220 0 accccttgat tatttgcaga agcgcagaaa atcgaactct ggaacccttt cggggcatcc 5226 0 tttttcaaga atgaagaaaa aaataactaa aaaatcaagt tgttaggaag ttattcatgg 5232 0 ctagtgtacc aactcttttc tgggctaata gctatgattt gtttgtatta tttgtctctg 5238 0 tctctattat ttttgacatc catgcgactt ctgatattga taacctcagt tgtggagttc 5244 0 tgtctgcgct tccgggagga cgcatatcaa aactacagga tcttctgtta aacactgtaa 5250 0 agccatctac attgcatgtt gttgagtcta agatacaatt tttagtagat gatttatctg 5256 0 ctataggcct agatatttca ggttgatgcc aagtgtgtcc tgaaaaaata ctttttattg 5262 0 aaaatggcat ttttatcctc acattatgtc tttctcttat agtgcaattt aatgtattta 5268 0 gaaacattaa actatgaatc taaaaaggct acgcagagta ctgttacact ttaacaaatc 5274 0 atatttacca ctctggaaat gggatggctg gttcataaaa taatgagtct ttttcaacgg 5280 0 ttgttacatt ggtgtactga tgattatgcc ttgtcgctaa gagctaccat aaccgtacag 5286 0 cgtgattcat ccatggcgaa taaatcgact gataaatccc cctgagtttc agctcttgct 5292 0 gttggacctt gcccgtttcg ctatggaacg cgtaccagct agagaatatt attcgttctc 5298 0 ctccaatgtt acgcaagttt tgtaaacggt aaccaatcgt gattagtcct gcatgtaacg 5304 0 gacatcaagc tgtctggttg atttttattg ccagtagttc gagagagcag acaactgcgt 5310 0 ccgatggaaa aatgggcacg acagggtatt caggcaacct cgctgaggag gcttatggta 5316 0 cagattgtaa tgtgaagtat aaaacgttaa aaattccatt ttagaaacta aatagctgta 5322 0 atataagttc gatctaatct actattttga cagacagatt gtatcaagaa ttagggagta 5328 0 tgaaatagat ggcaataact agtaaaatta attttgcaac atttaaatcg aaccatacag 5334 0 tcaaattcta gtgcatatat tttgtgtggc taatatgcaa aaatattgtt ctattagatt 5340 0 aaaatggcat tcatctttgc tgacaatcat ttccggaaca aagggttcac ggctgagagg 5346 0 gtgtggagcg ttgcgtcgga taagttcagt gagtgcattg tggtcatata atgaacatat 5352 0 ttctgagttt tttgcatttc tgacaaaaac accagtttca ggaatgcata atgttatcgg 5358 0 gcaattcagg tgttgttcat gacaggaaaa gtcttgatga ctaacagtaa atgcatgaga 5364 0 gttaattttg ttttgtattg cactactgac gttttggcgc gtacatgggg ttgcacggct 5370 0 ctgttccata tataaacgga atgcctgcaa aaaagtatgg cctctgttaa gctgtatctc 5376 0 cagattttct gcgagaaggc gatgccctct tgcactaagg cgatccaaca gtccgccgga 5382 0 aaccggttcc acgctaaaac tgtccataaa tgaaatatga tgaagtctca tagtgcggcc 5388 0 tctcacaaca agctgttcac tctgactaac tcttccgaca tgacgtaaag cctccagttc 5394 0 actttcagac aatactcttt cactcgaaaa gtttaatatg acaggcatat tttctccctc 5400 0 tttagtctat gttattgaac catattggtg acaggagtca agatactaaa tatgtgatag 5406 0 gattcaaaca aaaaattaaa ttttgaacga atgctattta cacatgtatt tttttaatta 5412 0 aaatgattgt atacaatttt tgtaagcaaa ttttaatgaa aaggatttgt tatgccagta 5418 0 aatgcgacag gtgtgtcctt cagctctttt ggtatcagtt atcataaaga taattctttc 5424 0 cggggcacca tccgtgggaa gaatgatgag gtcgtgaagt gttcaatggg agagcgctct 5430 0 atccgcttta atgttaacaa atttagcggc tgtatactgg agacggtaag caggcagagt 5436 0 actaaagata ttcatggatg ggtaagtgat gaacggacag tatatccgtc aagggttatc 5442 0 aaccaagaga ttgataattg ctgccttcaa aaaaatgcaa aaatttcttc tgaagagagg 5448 0 aaaatggtct tttctcttgt aagtaaggag tttgaactaa ctcttgatgt taaagcggca 5454 0 caaagttcta ttaatcatat aataatagga aatgcttctt ttggcaaaaa aatggatgct 5460 0 ctttgcgatg gtatgagccg agctgtaaaa aacagtacaa cagattacat agcaaacgtg 5466 0 cttgcagaca agttttatca gaaacatatc gccccgggtg ttgatattgt aaaactacga 5472 0 aatgaaatcc caggttatat gagtcgtgtt atacaggggt aaggttggag gaggctatgc 5478 0 gccagtatca ttggttttca tcctgtaaaa agatatgagt aaaatataca acaggcgtta 5484 0 cactatatgt atgtatccaa ataactcata gttcacctgt acagttataa atcgtaaaga 5490 0 aaattgcagc gcgtcgtacg cagaaacgtg ctgtgattga ctatttatag ctttgtcaca 5496 0 acgacaagat tcagtagtgt ttacacgggc gggagaaatg acggaataac taaatagctg 5502 0 cgcctaatat cgcacatttt tgccagccca tgtttgcctt cggggaatgg actgacggat 5508 0 tccataaaat ggcgaacttt ttcaatagtt gccacattga gcggcactga tgattacgcg 5514 0 ttattgtggc gtgaagtatc tgccatagct attcaaaatg attcacccat ggagattaaa 5520 0 ccggctgata aatgactctg cacttcggtt tatccttcag ccagcgctgg gtttcccggc 5526 0 ctttgtggat aatgtagttg tcctcgagca gcgtgatggt tttcgtccga cagtatgtag 5532 0 ctttaagccg cttcagcagt ctgatgaaca gcgccgaact tttgctgttg gcgcccacac 5538 0 agctgactta acctgtcccg ctgtgcagcg ctacgtccag agaatatttt tcattttgtt 5544 0 ccggcgtgac ccctcgtttt tgcttcccga gcagtttcca gtccgcaccg attttgggat 5550 0 taagatggat aaatacttca tcttcataaa agaccggatg ctctgtgctg cattcgtcca 5556 0 gtgcgttatg gattgttgcc atctttttat ctttaggcgg ggcacggata cgtagagttg 5562 0 gcgcagccct tcgccacaca agccccacag acgacaacca gcggcgaatg gttccagcat 5568 0 gtaacaggca gccggttatc tcattgattt ttattgtcag cagttctgta ctccagcgtg 5574 0 aataattgta gccaaagtcg cgagtgaata ttttacctgt tcacgtaata gtgtgtagat 5580 0 atgcgcaaac ggccagcggc gggctcgctc ggcaggtaat gatttcagtc cctcaacacc 5586 0 cgactgtgtg aactagttaa tccagcgccc aacagaggaa cgggcgcagc atagtgtgcg 5592 0 ggcaacgtcg ctgacacggt cgccccggtg cagcatcagc atggctgtca gccttttatg 5598 0 gatggctttc tgtattaggc gtcgttcgtc acgggaaatt ggtggtatga tcgacattgc 5604 0 tcagtccggt tggtgatttg tattgatttg gcgattgatc agatcgcaca atcgggttga 5610 0 gttccctcta aatgatctac tattctgcgc agctatttag tgagtatata ttttatgctt 5616 0 ataaattaga ttaaaataat cctacaatta ttctgatgga gtattgctgt ggaggatggc 5622 0 tttttgttaa ttatcgaaaa gtaagatata tgctttaggg ataaaattat gccattttca 5628 0 tttaatttgt cttctggaaa ttacttgtca acacaagatg ttgaagtttt acaacgtgcg 5634 0 accagagatc atcaaatgga aagactcaca ataggagaat gatcgttttc tgttcgctat 5640 0 cagagtgcta tggacgcttt tattgtagat cctgttcaag gggaactata ttcgggttta 5646 0 agccatacag aactagccga tatcattaga ttggctgatt ctgttgaaaa tcaattgaat 5652 0 ggaggcaatt catttcttga tgtattcagt acatatatgg ggcaggttat ttctgaattt 5658 0 atgcatagta atgataacag aattgaattg ttacagcggc gattacattc atgttcattt 5664 0 ttagttaata ttgaagaaat gtcttacata gatgaagcat tacagtgccc gattacgctg 5670 0 gcaattcctc aacgaggtgt ttttttaaga aatgctgaag gttccagagt atgtagttta 5676 0 tatgatgaaa tggctctttc tcgtataatt aatgatggga tgcatcaccc actaagcaga 5682 0 gagccaataa cattatcaat gcttgtggcc agagagcagt gtgagtttga ttgcagtatc 5688 0 ggtcacttta cggtgaggag tgattgttat tcagtgtaga ctcggtacac gattttgtgt 5694 0 gaagagactc ttattaaaag ttagcatcaa agcggtcatc aaacttgata ataaagtgac 5700 0 tcattgctat tcgctggtcc ttaagggatg tatcgtgaac tgaatagcaa gtagccaccg 5706 0 tcctgatttc aacgcattat caggcgcttc tgaagcggca tacctgcatg acaggatgag 5712 0 tgcaaagggg cgctgttacg ataatgctag ggcggaaagt ttcttccact cactaaaagt 5718 0 cgaatgcatt tacggctaat attttatgag tcgggaaata atgcagacgg ctgtgtttaa 5724 0 ttagatctag tgtgattaca atcggtggtg ccgacacagt acttgtggct gtctcagcac 5730 0 ggaactgttt tgaaaaacag aaccttgatt agggctgtgt ccacattacg taggtaggat 5736 0 caccccacag gcaccacatg tcatgcatgg attaggattg aatgataaat cgtaaagaaa 5742 0 actgcaacac ctcgcgtgta gcacctggtt agcgaacttt cgaaagtacg agtattgtat 5748 0 gatttccagc agttatcaat tttacgtatt aatcagtgaa tcaacaactc gtcagcagac 5754 0 tctctttgct gttgaatttt ttggaacgtg tatagggcag aaatttttgt tttgggacat 5760 0 ggttgggacg ccgtagtaca tacgaactct gccgaataac gtatgatatt attttttaat 5766 0 ctcttggaat acattataga aacagaatgc tcttgggcga tttttagtga ttgtttaaat 5772 0 agccctgtca tgcagttaaa gtggcgggca tcctcttcaa ggatggtgat cctcaaccgc 5778 0 acccatttag gatgcgacta ttgtggtaga acaatgtaaa ccataattaa tctgcgtgcg 5784 0 gatacatgct tcatagatag gatattctgg tttgggttgt gaatgtgttg gtcatcgagt 5790 0 ggacaataag gtaagaggag taactcctgc aaaacaaaaa aagagttcaa caaaatcaat 5796 0 cagttaaaaa cacgagagat ctgtataaaa aagcatcgta aattctgtat ttttccttta 5802 0 aatataatat gttattgagt tttgtaaaat ctaccagtgt ggtacatgga tatcgatacc 5808 0 accgccaatt ataaactggg cggtgcacag caacatgata gcgtacgcct cgatccgtgg 5814 0 gtgtttatgt tctcagcagg atatcgtttt taatt 5817 5 <210> 338 <211> 377 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44..1174) <400> 338 Met Ala Arg Pro Arg Lys Tyr Lys Thr Asp Val Pro Gly Leu Ser Pro 1 5 10 15 Tyr Phe Asp Lys Arg Asn Asn Lys Val Tyr Trp Arg Tyr Arg His Pro 20 25 30 Ile Thr Gly Lys Asn His Gly Leu Gly Ser Ile Asp Gln Lys Leu Ala 35 40 45 Glu Thr Ile Ala Ala Glu Ala Asn Ser Arg Leu Ala Arg Gln Gln Met 50 55 60 Glu Gln Met Leu Ser Leu Gln Glu Lys Ile Ile Ser Asp Thr Gly Gly 65 70 75 80 Ser Ser Thr Val Thr Ile Phe Leu Asn Asn Tyr Arg Lys Ile Gln Gln 85 90 95 Glu Arg Tyr Glu Asn Gly Glu Ile Lys Leu Asn Thr Leu Lys Gln Lys 100 105 110 Ala Ala Pro Leu Arg Val Phe Asp Glu Arg Phe Gly Thr Arg Pro Leu 115 120 125 Asp Ala Ile Thr Val Lys Asp Val Val Ser Val Leu Glu Glu Tyr Lys 130 135 140 Ala Arg Gly His Asn Arg Met Gly Gln Ile Phe Arg Lys Val Leu Ile 145 150 155 160 Asp Val Phe Arg Glu Ala Gln Gln Thr Gly Asp Val Pro Pro Gly Phe 165 170 175 Asn Pro Ala Glu Ser Ala Lys Lys Pro Gln Val Arg Ile Ser Arg Gln 180 185 190 Arg Leu Thr Phe Asp Glu Trp Met Met Ile Tyr Asn Ala Ala Glu Lys 195 200 205 Asp Gly Tyr Phe Leu Gln Arg Gly Met Leu Leu Ala Leu Met Thr Gly 210 215 220 Gln Arg Leu Ser Asp Ile Cys Lys Met Gln Phe Ser Asp Ile Arg Asp 225 230 235 240 Gly Tyr Leu His Val Glu Gln Gln Lys Thr Gly Thr Arg Ile Ala Ile 245 250 255 Pro Leu Ala Leu Arg Cys Asp Lys Leu Asn Leu Thr Leu Asp Asp Val 260 265 270 Val Ser Ser Cys Arg Asp Cys Val Leu Ser Pro Trp Leu Leu His His 275 280 285 His His Ala Lys Gly Thr Ala Lys Arg Gly Gly Met Val Lys Pro Ala 290 295 300 Thr Leu Thr Val Ala Phe Lys Lys Ala Arg Asp Ser Val Asp Tyr Asn 305 310 315 320 Trp Arg Ala Asn Gly Thr Pro Pro Ser Phe His Glu Gln Arg Ser Leu 325 330 335 Ser Glu Arg Leu Phe Arg Glu Gln Gly Val Asp Thr Lys Ile Leu Leu 340 345 350 Gly His Ser Asn Gln Lys Met Thr Asp Ile Tyr Asn Asp Ala Arg Gly 355 360 365 Lys Glu Trp Lys Lys Leu Val Ile * 370 375 <210> 339 <211> 83 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1152..1400) <400> 339 Met Ala Arg Leu Ile Leu Leu Thr Glu Trp Ala Lys Glu Glu Phe Ser 1 5 10 15 Glu Pro Val Pro Thr Pro Ser Thr Leu Ser Lys Tyr Ala Lys Ala Gly 20 25 30 Met Ile Phe Pro Leu Pro Lys Lys Val Gly Arg Arg Trp Arg Val Asp 35 40 45 Pro Gln Ala Arg Phe Val Gly Met Val Asn Lys Pro Glu Val Ile Ala 50 55 60 Thr Asp His Pro Ala Leu Lys Arg Ile Leu Glu Asp Gly Ala Pro Ala 65 70 75 80 Lys Ile * <210> 340 <211> 824 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1465..3936) <400> 340 Met Ser Lys Val Phe Ile Cys Ala Ala Ile Pro Asp Glu Gln Ala Ile 1 5 10 15 Lys Glu Glu Gly Ala Val Ala Val Ala Thr Ala Ile Glu Ala Gly Asp 20 25 30 Glu Arg Arg Ala Arg Ala Lys Phe His Trp Gln Phe Leu Glu His Tyr 35 40 45 Pro Ala Ala Gln Asp Cys Ala Tyr Lys Phe Leu Val Cys Glu Asp Lys 50 55 60 Pro Gly Ile Pro Arg Pro Ala Leu Asp Ser Trp Asp Ala Glu Tyr Met 65 70 75 80 Gln Glu Asn Arg Trp Asp Glu Gly Ala Ala Ser Phe Val Pro Val Glu 85 90 95 Thr Glu Ser Asp Pro Met Asn Val Ala Phe Asp Lys Leu Ala Pro Glu 100 105 110 Val Gln Asn Ala Val Met Val Lys Phe Asp Thr Cys Glu Asn Ile Thr 115 120 125 Val Asp Met Val Ile Ser Ala Gln Glu Leu Leu Gln Glu Asp Met Ala 130 135 140 Thr Phe Asp Gly His Ile Val Glu Ala Leu Met Lys Met Pro Glu Val 145 150 155 160 Asn Ala Met Tyr Pro Glu Leu Lys Leu His Ala Ile Gly Trp Val Lys 165 170 175 His Lys Cys Lys Pro Gly Ala Lys Trp Pro Glu Ile Gln Ala Glu Met 180 185 190 Arg Ile Trp Lys Lys Arg Arg Glu Gly Glu Arg Lys Glu Thr Gly Lys 195 200 205 Tyr Thr Ser Val Val Asp Leu Ala Arg Ala Arg Val His Arg Gln His 210 215 220 Thr Glu Asn Ser Ala Glu Lys Ile Pro Pro Val Thr Ala Val Ile Arg 225 230 235 240 Arg Glu Tyr Lys Gln Thr Trp Lys Thr Leu Asp Asp Glu Leu Ala Tyr 245 250 255 Ala Leu Trp Pro Gly Asp Val Asp Ala Gly Asn Ile Asp Gly Ser Ile 260 265 270 His Arg Trp Ala Lys Asn Glu Val Ile Asp Asn Asp Arg Glu Asp Trp 275 280 285 Lys Arg Ile Ser Ala Ser Met Arg Lys Gln Pro Asp Ala Leu Arg Tyr 290 295 300 Asp Arg Gln Thr Ile Phe Gly Leu Val Arg Glu Arg Pro Ile Asp Ile 305 310 315 320 His Lys Asp Pro Val Ala Leu Asn Lys Tyr Ile Thr Glu Tyr Leu Thr 325 330 335 Thr Lys Gly Val Phe Glu Asp Glu Gly Thr Asn Gln Ser Ala Thr Asp 340 345 350 Thr Leu Ser Ser Pro Val Pro Glu Thr Asp Ala Val Glu Thr Ala Ile 355 360 365 Pro Asp Asn Glu Lys Thr Glu Cys Lys Val Glu Val Glu Pro Ser Val 370 375 380 Glu Arg Glu Gly Pro Phe Tyr Phe Leu Phe Thr Asp Lys Asp Gly Glu 385 390 395 400 Lys Tyr Gly Arg Ala Asn Lys Leu Ser Gly Leu Asp Lys Ala Leu Ala 405 410 415 Ala Gly Ala Thr Glu Ile Thr Lys Glu Glu Tyr Phe Ala Arg Lys Asn 420 425 430 Gly Thr Tyr Thr Gly Leu Pro Gln Asn Ala Asn Thr Ala Gln Asn Ser 435 440 445 Glu Gln Pro Glu Pro Val Lys Val Thr Ala Asp Glu Val Lys Lys Ile 450 455 460 Met Gln Ala Ala Asn Ile Ser Gln Pro Asp Ala Asn Gln Leu Leu Ala 465 470 475 480 Ala Ser Arg Gly Glu Phe Val Ala Gly Ile Ser Asp Pro Asn Asp Pro 485 490 495 Lys Trp Val Lys Gly Ile Glu Thr Arg Asp Ser Val Asn Gln Asn Gln 500 505 510 Gln Glu Thr Glu Gln Asn Asp Gln Lys Ala Glu Gln Asn Ser Pro Asn 515 520 525 Thr Gln Gln Asn Glu Pro Glu Thr Lys Gln Pro Glu Pro Val Ala Gln 530 535 540 Gln Glu Pro Glu Lys Val Cys Thr Ala Cys Gly Gln Thr Gly Gly Gly 545 550 555 560 Asn Cys Pro Asp Cys Gly Ala Val Met Gly Asp Ala Thr Tyr Gln Glu 565 570 575 Thr Phe Asp Glu Glu Tyr Gln Val Glu Val Gln Glu Asp Asp Pro Glu 580 585 590 Glu Met Glu Gly Ala Glu His Pro His Lys Glu Asn Thr Asp Gly Asn 595 600 605 Gln His His Asp Ser Asp Asn Glu Thr Gly Glu Thr Ala Asp His Ser 610 615 620 Ile Lys Val Asn Gly His Gln Glu Ile Thr Ser Thr Ser Arg Thr Cys 625 630 635 640 Asp His Leu Met Ile Asp Leu Glu Thr Met Gly Lys Asn Pro Asp Ala 645 650 655 Pro Ile Ile Ser Ile Gly Ala Ile Phe Phe Asp Pro Gln Thr Gly Asp 660 665 670 Met Gly Pro Glu Phe Ser Lys Thr Ile Asp Leu Glu Thr Ala Gly Gly 675 680 685 Val Ile Asp Arg Asp Thr Ile Lys Trp Trp Leu Lys Gln Ser Arg Glu 690 695 700 Ala Gln Ser Ala Ile Met Thr Asp Glu Ile Pro Leu Asp Asp Ala Leu 705 710 715 720 Leu Gln Leu Arg Glu Phe Ile Asp Glu Asn Ser Gly Glu Phe Phe Val 725 730 735 Gln Val Trp Gly Asn Gly Ala Asn Phe Asp Asn Thr Ile Leu Arg Arg 740 745 750 Ser Tyr Glu Arg Gln Gly Ile Pro Cys Pro Trp Arg Tyr Tyr Asn Asp 755 760 765 Arg Asp Val Arg Thr Ile Val Glu Leu Gly Lys Ala Ile Asp Phe Asp 770 775 780 Ala Arg Thr Ala Ile Pro Phe Glu Gly Glu Arg His Asn Ala Leu Asp 785 790 795 800 Asp Ala Arg Tyr Gln Ala Lys Tyr Val Ser Val Ile Trp Gln Lys Leu 805 810 815 Ile Pro Asn Gln Ala Asp Phe * 820 <210> 341 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4029..4220) <400> 341 Met Asn Thr Ala Phe Ala Leu Val Leu Thr Val Phe Leu Val Ser Gly 1 5 10 15 Glu Pro Val Asp Ile Ala Val Ser Val His Arg Thr Met Gln Glu Cys 20 25 30 Val Thr Ala Ala Thr Glu Gln Lys Ile Pro Gly Asn Cys Tyr Pro Val 35 40 45 Asp Lys Val Ile His Gln Asp Asn Asn Glu Ile Pro Ala Gly Leu * 50 55 60 <210> 342 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4217..4405) <400> 342 Met Glu Thr Leu Leu Pro Asn Val Asn Thr Ser Glu Gly Cys Phe Glu 1 5 10 15 Ile Gly Val Thr Ile Ser Asn Pro Val Phe Thr Glu Asp Ala Ile Asn 20 25 30 Lys Arg Lys His Glu Arg Glu Leu Leu Asn Lys Ile Cys Ile Leu Ser 35 40 45 Met Leu Ala Arg Leu Arg Pro Ile Gln Lys Gly Cys Trp Gln * 50 55 60 <210> 343 <211> 78 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4879..5112) <400> 343 Met Leu Lys Ser Thr Leu Ile Ala Lys Cys Leu Tyr Gln Asn Arg Met 1 5 10 15 Val Ser Ser Ile Ser Ile Gly Glu Ser Ala Val Lys Ser Ile Phe Glu 20 25 30 Glu Tyr Phe Pro Gly His Asp Phe Asn Lys Trp Asn Thr Lys Leu Pro 35 40 45 Pro Ala Val Ser Thr Arg Ile Leu Lys Ala Thr Glu Arg Ala Ser Thr 50 55 60 Ile Arg Val Asn Tyr Phe Ile Lys Asp Leu Trp Asp Leu * 65 70 75 <210> 344 <211> 136 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5090..5497) <400> 344 Met Glu Phe Lys Asp Leu Pro Thr Pro Leu Gln Glu Met Ala Ser Asn 1 5 10 15 Ile Val Arg Ser Gln Leu Ala Thr Leu Asp Leu Ser Thr Ala Glu Lys 20 25 30 Glu Thr Ile Asp Asn Met Val Arg Asn Val Arg Asn Ala Phe Ser Gly 35 40 45 Leu Tyr Gly Ser Asp Asn Gln Lys Gln Glu Ser Asp Val Asn Lys Arg 50 55 60 Val Ile Ser Val Cys Val Asn Gly His Val Leu Ser Ser Ile Lys Thr 65 70 75 80 Glu Thr Ala Thr Val Phe Asp Cys Leu Cys Ile Val Gln Ser Leu Val 85 90 95 Asp Ala Leu Phe Arg Ser Val Asn Leu Glu Asn Asp Ala Asn Leu Arg 100 105 110 Gly Arg Ile Ile Ala His Pro Tyr Ala His Thr Leu Gly Ser Val Asp 115 120 125 Ile Lys Asp Pro Thr Asn Leu * 130 135 <210> 345 <211> 73 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5520..5738) <400> 345 Met Gln Lys Arg Asp Pro Val Ile Ile Ala Pro Asp Tyr Thr Asp Asp 1 5 10 15 Glu Leu Tyr Glu Trp Met His Gln Lys Ile Lys Ala Val Gln Asp Leu 20 25 30 Lys Trp Ala Asn Glu Ala Arg Ala Lys Gln Ala Glu Asn Leu Ser Ala 35 40 45 Leu Glu Gln Asp Ile Thr Asn Leu Glu Lys Ala Ala Ala Leu Ser Ile 50 55 60 Ala Arg Met Ile Thr Tyr Pro Arg * 65 70 <210> 346 <211> 136 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6374..6781) <400> 346 Met Lys Asn Glu Thr Phe Gly Ala Arg Leu Leu Tyr Arg Arg Lys Lys 1 5 10 15 Leu Lys Leu Ser Gln Ala Ala Leu Gly Lys Leu Val Lys Val Ala His 20 25 30 Val Thr Ile Ser Gln Trp Glu Arg Asp Glu Thr Gln Pro Ala Gly Lys 35 40 45 Arg Leu Phe Ala Leu Ser Gln Ala Leu Gln Cys Ser Pro Thr Trp Leu 50 55 60 Leu Phe Gly Asp Glu Asp Lys Gln Pro Gly Glu Pro Ile Pro Asp Asn 65 70 75 80 Gln Pro Val Asn Leu Thr Glu Asp Gln Lys Glu Leu Leu Gln Leu Phe 85 90 95 Asp Ala Leu Pro Glu Ser Glu Gln Lys Ala Leu Leu Ser Glu Met Arg 100 105 110 Ala Arg Val Glu Asn Phe Asn Lys Leu Phe Glu Glu Leu Leu Lys Ala 115 120 125 Arg Lys Arg Ser Ala Asn Lys * 130 135 <210> 347 <211> 76 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6858..7085) <400> 347 Met Leu Lys Ile Asp Ala Ile Ala Phe Phe Gly Ser Lys Thr Lys Leu 1 5 10 15 Ala Asn Val Ala Gly Val Arg Leu Ala Ser Val Ala Ala Trp Gly Glu 20 25 30 Leu Val Pro Glu Gly Arg Ala Met Arg Leu Gln Glu Ala Ser Gly Gly 35 40 45 Glu Leu Gln Tyr Asp Pro Lys Val Tyr Asp Glu Tyr Arg Lys Ala Lys 50 55 60 Arg Ala Gly Arg Leu Asn Asn Glu Asn His His * 65 70 75 <210> 348 <211> 184 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7069..7620) <400> 348 Met Lys Ile Thr Thr Glu Gln Val Cys Glu Ala Leu Asp Thr Trp Val 1 5 10 15 Cys Arg Pro Gly Met Thr Gln Glu Gln Ala Thr Ile Leu Ile Thr Glu 20 25 30 Ala Phe Trp Ala Leu Lys Glu Arg Pro Asn Ile Asp Val Gln Arg Val 35 40 45 Thr Phe Asn Asp Gly Glu Val Asp Gln Arg Ala Leu Gly Val Asn Arg 50 55 60 Val Lys Ile Phe Glu Arg Trp Lys Ala Ile Asp Thr Arg Asp Lys Arg 65 70 75 80 Asp Lys Phe Thr Ala Leu Ile Pro Ala Ile Met Glu Ala Ile Arg Ile 85 90 95 Ser Asp Phe Arg Leu Tyr Cys Glu Ile Thr Asp Gly Lys Ser Ile Thr 100 105 110 Tyr Met Ile Ala Gly Leu Asn Lys Glu Tyr Gly Asp Val Val Glu Ser 115 120 125 Gly Leu Leu Phe Ala Asp Pro Val Val Val Glu Arg Glu Thr Asp Glu 130 135 140 Leu Ile Glu Lys Ala Ile Ala Phe Lys His Ala Tyr Arg Gln Gln Tyr 145 150 155 160 Gln Tyr Tyr Phe Ala Asp Lys Gln Met Ser Ala Arg Gly Ala Tyr Glu 165 170 175 Tyr Arg Cys Thr Thr Met Gly * 180 <210> 349 <211> 347 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7592..8632) <400> 349 Met Ser Ile Asp Ala Leu Arg Trp Ala Lys Lys Val Lys Thr Gly Ser 1 5 10 15 Ser Ser Ser Lys Ser Val Leu Thr Trp Leu Ala Asp Met Cys Gly Ala 20 25 30 Asp Leu Cys Ala Tyr Pro Ser Val Ser Ala Leu Ala Glu Val Thr Glu 35 40 45 Leu Asn Lys Lys Thr Val Gln Asp Ser Leu Arg His Leu Met Glu Ile 50 55 60 Gly Leu Ile Val Asp Thr Gly Glu Arg Lys Gly Arg Thr Lys Gln Ile 65 70 75 80 Val Val Tyr Arg Leu Ile Gly Val Glu Glu Ser Val Ala Glu Pro Glu 85 90 95 Tyr Thr Gln Lys Arg Glu Ser Leu Lys Val Gly Lys Ile Gly Ala Val 100 105 110 Asn Lys Asn Ser Thr Glu Asn Gly Tyr Val Ser Ala Gln Asn Arg Pro 115 120 125 Lys Asn Arg Thr Leu Ser Cys Met Glu Asn Asn Gln Arg His Pro Asn 130 135 140 Phe Pro Ser Lys Thr Pro Lys Asn Gly Ser Arg Asn Pro Lys Glu Pro 145 150 155 160 Lys Asp Leu Asn Pro Thr His Asn Ala Arg Glu Ser Ala Pro Thr Ser 165 170 175 Glu Gln Glu Val Leu Ser Leu Gln Ala Ala Pro Pro Val Phe Leu Tyr 180 185 190 Gly Leu Ser Glu Pro Ile Gly Lys Phe Pro Met Ser Asp Ser Trp Tyr 195 200 205 Pro Ser Arg Asp Phe Arg Arg Arg Ala Ala Leu Trp Gly Met Ala Leu 210 215 220 Pro Glu Thr Glu Phe Thr Pro Ala Glu Leu Ala Ala Phe Arg Asp Tyr 225 230 235 240 Trp Ala Ala Glu Gly Lys Val Phe Thr Gln Ile Gln Trp Glu Gln Lys 245 250 255 Phe Ala Arg His Val Asn His Val Arg Ala Gln Val Lys Pro Val Ser 260 265 270 Lys Gly Val Asn His Ala Ala Ala Pro Gly Gly Thr Ala Ser Arg Ala 275 280 285 Val Gln Glu Ile Arg Ala Ala Arg Glu Gln Trp Glu Arg Glu Asn Gly 290 295 300 Phe Ile Ser Asp Gly Asn Gly Leu Glu Ala Val Gly Thr His Gly Gly 305 310 315 320 Gly Leu Phe Glu Pro Leu Asp Pro Glu Glu Arg Gly Arg Thr Phe Glu 325 330 335 Ala Leu Asp Cys Thr Asp Trp Arg Asp Asp * 340 345 <210> 350 <211> 222 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8421..9086) <400> 350 Met Gln Gln His Gln Val Ala Pro His His Gly Gln Phe Arg Lys Phe 1 5 10 15 Gly Gln His Val Ser Ser Gly Asn Val Lys Thr Asp Leu Ser Ala Thr 20 25 30 Glu Thr Ala Trp Lys Leu Trp Glu Leu Met Gly Val Val Tyr Ser Asn 35 40 45 Arg Trp Ile Gln Lys Asn Gly Ala Ala Pro Ser Lys Leu Trp Ile Ala 50 55 60 Gln Ile Gly Ala Met Thr Glu Gln Gln Ile Arg Gln Val Cys Arg Gln 65 70 75 80 Cys Met Asp Arg Cys Arg Ala Gly Glu Thr Trp Pro Pro Asp Leu Ala 85 90 95 Glu Phe Val Ala Leu Ile Ser Lys Ser Gly Ala Asn Pro Phe Gly Leu 100 105 110 Thr Val Asp Ala Val Met Glu Glu Tyr Arg Arg Trp Arg Asn Glu Ser 115 120 125 Trp Arg Tyr Asp Gly Ser Asp Lys Tyr Pro Trp Ser Gln Pro Val Leu 130 135 140 Tyr His Ile Cys Leu Glu Met Arg Ser Lys Gly Ile Glu Arg Gln Met 145 150 155 160 Thr Glu Gly Glu Leu Lys Arg Leu Ala Glu Arg Gln Leu Thr Lys Trp 165 170 175 Ala Lys His Val Ser Asn Gly Leu Ser Val Pro Pro Val Arg Arg Gln 180 185 190 Leu Ala Ala Pro Lys Arg Pro Ser Gly Pro Thr Pro Ile Glu Leu Leu 195 200 205 Lys Gln Glu Tyr Glu Arg Arg Lys Ala Ala Gly Phe Val * 210 215 220 <210> 351 <211> 104 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9984..10295) <400> 351 Val Ile Phe Thr Ser Gln Gln Asn Ile Arg Ser Ala Ile Thr Val Lys 1 5 10 15 Asn Tyr Gly Ala Asp Thr Phe Val Pro Leu Glu Met Thr Val Pro Lys 20 25 30 Phe Arg Gly Glu Glu His Val Arg Trp Asp Gly Arg Ala Arg Phe Lys 35 40 45 Gly Gln Val Met Ala Pro Ala Cys Thr Leu Ala Met Glu Ala Ala Trp 50 55 60 Arg Glu Ile Asp Met Gly Thr Thr Pro Leu Arg Asp Leu Leu Pro Val 65 70 75 80 Gln Arg Ile Asn Ser Cys Tyr Gly Tyr Thr Thr Val Ile Leu Gln Val 85 90 95 Gln Glu Ser Arg Ser Thr Arg * 100 <210> 352 <211> 54 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10301..10462) <400> 352 Val Arg Val Thr Phe Asp Val Ile Pro Val Glu Thr Pro Asp Lys Phe 1 5 10 15 Ser Leu Thr Gly His Ala Glu Gly Ile Asn Leu Gln Ile Met Asp Asn 20 25 30 Tyr Gly Tyr Pro Ala Arg Ala Gly Lys Ser Met Pro Pro Leu Ile Leu 35 40 45 Ser Gly Arg Trp Thr * 50 <210> 353 <211> 253 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10714..11472) <400> 353 Met Arg Asn Ile Met Ala Gly Phe Leu Ile Phe Leu Ser Ser Ala Ala 1 5 10 15 Tyr Ala Asp Ile Asn Leu Tyr Gly Pro Gly Gly Pro His Thr Ala Leu 20 25 30 Leu Asp Ala Ala Lys Leu Tyr Ala Glu Lys Thr Gly Ile Ile Val Asn 35 40 45 Val His Tyr Gly Pro Gln Asn Lys Trp Asn Glu Asp Ala Lys Lys Asn 50 55 60 Ala Asp Ile Leu Phe Gly Ala Ser Glu Gln Ser Ala Leu Ala Ile Ile 65 70 75 80 Arg Asp His Lys Asp Ser Phe Ser Glu Lys Asp Ile Gln Pro Leu Tyr 85 90 95 Leu Arg Lys Ser Ile Leu Leu Val Lys Lys Gly Asn Pro Lys Asn Ile 100 105 110 Arg Ser Ile Asp Asp Leu Thr Arg Pro Gly Ile Gly Val Ile Val Asn 115 120 125 Asp Gly Gly Gly Thr Ser Asn Thr Ser Gly Thr Gly Val Trp Glu Asp 130 135 140 Ile Ala Gly Arg Lys Gly Asn Ile Glu Thr Val Ala Ala Ile Arg Lys 145 150 155 160 Asn Ile Ile Leu Tyr Ala Pro Asn Ser Gly Thr Ala Arg Lys Ala Leu 165 170 175 Glu Asn Gln Pro Gly Ala Asp Val Trp Ile Thr Trp Ala Asp Trp Ala 180 185 190 Ala Ser Asn Pro Glu Ile Gly Asp Val Val Glu Ile Ala Pro Asp Tyr 195 200 205 Val Ile Trp Arg Asp Met Asn Ile Thr Val Arg Gln Asp Ala Asn Asp 210 215 220 Glu Thr Arg Arg Phe Ala Glu Trp Leu Gln Thr Asp Glu Ala Ala Pro 225 230 235 240 Ala Phe Lys Lys Tyr Gly Trp Thr Arg Lys Gly Thr * 245 250 <210> 354 <211> 71 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11751..11963) <400> 354 Met Leu Val Thr Tyr Arg Leu Pro Leu Thr Asp Arg Lys Val Lys Glu 1 5 10 15 Lys Gln Ala Met Lys Gln Gln Lys Ala Met Leu Ile Ala Leu Ile Val 20 25 30 Ile Cys Leu Ile Val Ile Val Thr Ala Leu Val Thr Arg Lys Asp Leu 35 40 45 Cys Glu Val Arg Ile Arg Thr Gly Gln Thr Glu Val Ala Val Phe Thr 50 55 60 Ala Tyr Glu Pro Glu Glu * 65 70 <210> 355 <211> 86 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12184..12441) <400> 355 Met Arg Ile Glu Glu Leu Arg Glu Ile Phe Ser Glu Asp Gly Leu Tyr 1 5 10 15 Thr Val Arg Val Glu Lys Gly Ala Ile Val Ser His Cys Arg Ile Lys 20 25 30 Cys Leu Gln Ser Gln Gln Arg Lys Ser Gly Ala Ala Leu Ile His Phe 35 40 45 Val Asp Gly Leu Val Thr Asp Gly Phe Ile Leu Arg Ala Asn Glu Phe 50 55 60 Val Thr Ser Leu Pro Ser Leu Lys Glu Ala Gly Ile Lys Ala Gly Phe 65 70 75 80 Ser Ala Phe Glu Asp * 85 <210> 356 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12511..12789) <400> 356 Met Ala Gln Asn Ser Arg Leu His Asn Ser Asp Asn Ser Ala Val Phe 1 5 10 15 Ala Ser Arg His Gly Arg Arg Ser His Ala Phe Lys Ser Asp Trp Phe 20 25 30 Arg His Ala Pro Cys Thr Glu Glu Gln Ala Glu Trp Leu Ile Gln Asn 35 40 45 Tyr Arg Arg Arg Gly Tyr Glu Phe Arg Lys Ala Leu Ser Leu Asp Tyr 50 55 60 Arg His Trp Ile Ile Tyr Val Arg Leu Pro Tyr Ser Glu Arg Pro Pro 65 70 75 80 Arg Pro Ser Arg Thr Phe Gln Gln Arg Ile Trp Arg * 85 90 <210> 357 <211> 349 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12791..13837) <400> 357 Val Arg Val Leu Leu Arg Pro Val Pro Val Pro Glu Leu Gly Val Val 1 5 10 15 Val Leu Lys Pro Gly Arg Glu Ser Met Gln Val Phe His Asn Pro Arg 20 25 30 Val Leu Val Glu Pro Glu Pro Lys Ser Met Arg Gly Leu Pro Ser Gly 35 40 45 Ile Val Pro Ala Val Arg Gln Pro Leu Ala Glu Asp Lys Ser Leu Leu 50 55 60 Pro Phe Phe Ser Asn Glu Arg Val Ile Arg Ala Val Gly Gly Ala Gly 65 70 75 80 Ala Leu Ser Asp Trp Leu Leu Arg His Val Lys Ser Cys Gln Trp Pro 85 90 95 His Gly Asp Tyr His His Ser Glu Thr Val Ile His Arg Tyr Gly Thr 100 105 110 Gly Ala Met Val Leu Cys Trp His Cys Asp Asn Gln Leu Arg Asp Gln 115 120 125 Thr Ser Glu Ser Leu Glu Gln Leu Ala His Gln Asn Leu Ser Ala Trp 130 135 140 Met Ile Asp Val Ile Gly His Ala Ile Ser Gly Thr Gln Glu Arg Glu 145 150 155 160 Leu Ser Leu Ala Glu Leu Ser Trp Trp Ala Val Arg Asn Gln Val Ala 165 170 175 Asp Ala Leu Pro Glu Ala Val Leu Arg Arg Ser Leu Gly Leu Arg Ala 180 185 190 Glu Lys Ile Arg Ser Met Tyr Arg Glu Ser Asp Ile Val Pro Gly Glu 195 200 205 Gln Thr Ala Thr Ile Ile Leu Lys Gln Arg Thr Lys Asn Leu Ala Pro 210 215 220 Leu Pro His Ala His Gln Gln Asn Pro Pro Gln Glu Lys Thr Val Val 225 230 235 240 Ser Ile Ala Val Asp Pro Glu Ser Pro Glu Ser Phe Met Lys Arg Pro 245 250 255 Lys Arg Arg Arg Trp Val Asn Glu Lys Tyr Thr Arg Trp Val Lys Thr 260 265 270 Gln Pro Cys Ala Cys Cys Gly Lys Pro Ala Asp Asp Pro His His Leu 275 280 285 Ile Gly His Gly Gln Gly Gly Met Gly Thr Lys Ser His Asp Ile Phe 290 295 300 Thr Leu Pro Leu Cys Arg Glu His His Asn Glu Leu His Ala Asp Pro 305 310 315 320 Leu Ala Phe Glu Glu Lys His Gly Ser Gln Val Asp Leu Ile Phe Arg 325 330 335 Phe Leu Asp His Ala Phe Ala Thr Gly Val Leu Gly * 340 345 <210> 358 <211> 120 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13850..14209) <400> 358 Met Leu Ile Asp Leu Val Leu Pro Tyr Pro Pro Thr Val Asn Thr Tyr 1 5 10 15 Trp Arg Arg Arg Gly Ser Thr Tyr Phe Val Ser Lys Ala Gly Glu Arg 20 25 30 Tyr Arg Arg Ala Val Val Leu Ile Val Arg Gln Gln Arg Leu Lys Leu 35 40 45 Ser Leu Ser Gly Arg Leu Ala Ile Lys Ile Ile Ala Glu Pro Pro Asp 50 55 60 Lys Arg Arg Arg Asp Leu Asp Asn Ile Leu Lys Ala Pro Leu Asp Ala 65 70 75 80 Leu Thr His Ala Gly Val Leu Met Asp Asp Glu Gln Phe Asp Glu Ile 85 90 95 Asn Ile Val Arg Gly Gln Pro Val Ser Gly Gly Arg Leu Gly Val Lys 100 105 110 Ile Tyr Lys Ile Glu Ser Glu * 115 <210> 359 <211> 177 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14218..14748) <400> 359 Met Ile Tyr Pro Glu Ile Thr Gly Lys Ser Gly Glu His Leu Arg Leu 1 5 10 15 Asn Thr Leu Glu Ala Val Trp Ile Gln Gly Lys Leu Arg Met Trp Gly 20 25 30 Arg Trp Ser Tyr Ile Gly Gly Gly Lys Ser Gly Asn Met Phe Asn Arg 35 40 45 Leu Leu Val Ser Lys Lys Leu Thr Lys Thr Ala Val Asn Glu Val Leu 50 55 60 Arg Ser Met Lys Lys Ser Gly Leu Glu Lys Pro Glu Leu Glu Ala Phe 65 70 75 80 Phe Arg Asp Met Thr Arg Gly Lys Gln Lys Ser Trp Leu Ser His Cys 85 90 95 Thr Asp Thr Glu Ala Leu Ile Ile Asp Arg Val Ile Ser Glu Val Leu 100 105 110 Gly Glu Tyr Pro Gly Leu Ile Asn Ile Leu Arg Gln Arg Tyr Glu Gly 115 120 125 Arg Gly Met Ser Lys Arg Lys Met Ala Glu Cys Leu Asn Arg Thr His 130 135 140 Pro Glu Trp Cys Phe Ser Thr Cys Glu Lys Arg Ile Ala Gly Trp Leu 145 150 155 160 Ala Val Ala Glu His Met Leu Tyr Val Pro Met His Asp Ser Phe Arg 165 170 175 * <210> 360 <211> 107 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14867..15187) <400> 360 Val Ser Val Ile Tyr Ser Ser Ala Ile Asn Ser Leu Val Val Ile Asn 1 5 10 15 Thr Val Leu Ser Gly Cys Trp Leu Phe Arg Gln Glu Leu Leu Val Cys 20 25 30 His Val Asn Arg Lys Arg Glu Lys Asp Met Leu Lys Gln Gln Asp Met 35 40 45 Thr Glu Thr Ala Arg Val Val Phe Asn Glu Leu Ser Val Thr Asp Pro 50 55 60 Ala Thr Val Gly Glu Ile Ala Gln Asn Thr Tyr Leu Ser Arg Glu Arg 65 70 75 80 Cys Gln Leu Ile Leu Thr Gln Leu Val Met Ala Gly Leu Ala Asp Tyr 85 90 95 Gln Phe Gly Cys Tyr Arg Arg Leu Gln Ser * 100 105 <210> 361 <211> 353 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15338..16396) <400> 361 Met Leu Asn Thr Val Lys Ile Ser Ser Cys Glu Leu Ile Asn Ala Asp 1 5 10 15 Cys Leu Glu Phe Met Arg Ser Leu Pro Glu Asn Ser Val Asp Leu Ile 20 25 30 Val Thr Asp Pro Pro Tyr Phe Lys Val Lys Pro Glu Gly Trp Asp Asn 35 40 45 Gln Trp Ala Gly Asp Glu Asp Tyr Leu Lys Trp Leu Asp Gln Cys Leu 50 55 60 Ala Gln Phe Trp Arg Val Leu Lys Pro Ala Gly Ser Leu Tyr Leu Phe 65 70 75 80 Cys Gly His Arg Leu Ala Ser Asp Thr Glu Ile Met Met Arg Glu Arg 85 90 95 Phe Asn Val Leu Asn His Ile Ile Trp Ala Lys Pro Ser Gly Arg Trp 100 105 110 Asn Gly Cys Asn Lys Glu Ser Leu Arg Ala Tyr Phe Pro Ala Thr Glu 115 120 125 Arg Ile Leu Phe Ala Glu His Tyr Gln Gly Pro Tyr Arg Pro Lys Asp 130 135 140 Ala Gly Tyr Glu Ala Lys Gly Arg Thr Leu Lys Gln His Val Met Ala 145 150 155 160 Pro Leu Ile Ala Tyr Phe Arg Asp Ala Arg Ala Val Leu Gly Ile Thr 165 170 175 Ala Lys Gln Ile Ala Asp Ala Thr Gly Lys Lys Asn Met Val Ser His 180 185 190 Trp Phe Ser Ala Gly Gln Trp Gln Leu Pro Asn Glu Ser Asp Tyr Leu 195 200 205 Lys Leu Gln Ala Leu Phe Ala Arg Val Ala Glu Glu Lys His Gln Arg 210 215 220 Gly Glu Leu Glu Lys Pro His His Gln Leu Val Asp Thr Tyr Ala Ser 225 230 235 240 Leu Asn Arg Gln Tyr Ala Glu Leu Gln Ser Glu Tyr Lys His Leu Arg 245 250 255 Arg Tyr Phe Gly Val Thr Val Gln Val Pro Tyr Thr Asp Val Trp Thr 260 265 270 Tyr Lys Pro Val Gln Tyr Tyr Pro Gly Lys His Pro Cys Glu Lys Pro 275 280 285 Ala Glu Met Leu Gln Gln Ile Ile Ser Ala Ser Ser Arg Pro Gly Asp 290 295 300 Leu Val Ala Asp Phe Phe Met Gly Ser Gly Ser Thr Val Lys Ala Ala 305 310 315 320 Met Ala Leu Gly Arg Arg Ala Thr Gly Val Glu Leu Glu Thr Glu Arg 325 330 335 Phe Glu Gln Thr Val Arg Glu Val Gln Asp Leu Ile Ile Arg Asn Gly 340 345 350 * <210> 362 <211> 618 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17193..19046) <400> 362 Met Thr Phe Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Glu Lys Leu Thr His Lys Leu Lys Glu Gly Trp Gln Pro Phe 20 25 30 Gly Ser Pro Val Ala Ile Thr Pro Tyr Thr Leu Met Gln Val Ile Thr 35 40 45 Ala Glu Gly Asp Val Val Val Ser Gly Ala Thr Glu Pro Asp Trp Tyr 50 55 60 Tyr Val Ile Val Leu Ala Gly Gln Ser Asn Ala Met Ala Tyr Gly Glu 65 70 75 80 Gly Leu Pro Leu Pro Asp Ser Tyr Asp Ala Pro Asp Pro Arg Ile Lys 85 90 95 Gln Leu Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Ala Ala Cys Arg 100 105 110 Tyr Asn Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln Asp 115 120 125 Met Ser Thr Leu Asn His Pro Lys Ala Asp Leu Ser Lys Gly Gln Tyr 130 135 140 Gly Cys Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro Tyr 145 150 155 160 Ile Pro Asn Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly Gly 165 170 175 Ser Ala Phe Thr Gln Gly Ala Glu Gly Thr Phe Ser Ala Asp Ala Gly 180 185 190 Ala Ser Gln Asp Ser Ala Arg Trp Gly Val Gly Lys Pro Leu Tyr Gln 195 200 205 Asp Leu Ile Ala Arg Thr Lys Ala Ala Leu Gln Lys Asn Pro Lys Asn 210 215 220 Val Leu Leu Ala Val Cys Trp Met Gln Gly Glu Phe Asp Met Ser Ala 225 230 235 240 Ala Thr His Ala Gln Gln Pro Ala Leu Phe Thr Ala Met Leu Ala Gln 245 250 255 Phe Arg Ala Asp Leu Ser Val Phe Asn Ala Gln Cys His Gly Gly Ser 260 265 270 Ala Ala Asp Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Tyr Trp Lys 275 280 285 Asn Thr Tyr Gly Thr Gln Tyr Asn Thr Ile Tyr Gly Ala Tyr Lys Asn 290 295 300 Arg Glu Ser Glu Gly Val Tyr Phe Val Pro Phe Met Thr Asp Gly Asn 305 310 315 320 Gly Val Asn Thr Ala Thr Asn Ala Pro Ala Glu Asp Pro Asp Ile Pro 325 330 335 Ala Ser Gly Tyr Tyr Gly Ala Ala Ser Arg Thr Asn Gly Asn Gln Val 340 345 350 Ser Ser Asn Arg Pro Thr His Phe Ser Ser Trp Ala Arg Arg Ser Ile 355 360 365 Ile Pro Asp Arg Met Ala Thr Ala Ile Leu Asn Ala Ala Gly Arg Thr 370 375 380 Ser Ala Phe Ile Ser Gly Lys Ala Pro Glu Ile Lys Pro Ser Pro Gly 385 390 395 400 Gly Asn Thr Pro Ser Gly Pro Ser Ala Asp Thr Ser Val Arg Thr Ile 405 410 415 Ser Leu Leu Pro Ala Ala Gly Glu Ala Ala Ala Gln Gly Trp Ser Ile 420 425 430 Lys Asp Gly Gly Ile Gln Leu Ser Asp Gly Val Phe Lys Ile Thr Arg 435 440 445 Gln Ser Asn Lys Thr Trp Ser Leu Thr His Pro Val Asp Asp Ala Ile 450 455 460 Thr Leu Leu Thr Gln Gly Gly Arg Leu Thr Cys Lys Phe Arg Leu Ser 465 470 475 480 Gly Ala Leu Thr Asn Asn Gln Phe Gly Leu Gly Ile Tyr Leu Tyr Thr 485 490 495 Asp Ala Pro Val Pro Asp Gly Val Ala Met Thr Gly Thr Gly Asn Pro 500 505 510 Phe Leu Met Ser Tyr Phe Thr Gln Thr Thr Asp Gly Arg Val Asn Leu 515 520 525 Met His His Arg Lys Ala Gly Asn Thr Lys Leu Gly Glu Phe Gly Asp 530 535 540 Tyr Gly Asn Asp Trp Gln Thr Leu Glu Leu Val Phe Thr Ala Gly Ser 545 550 555 560 Ala Thr Val Thr Pro Lys Leu Asn Gly Val Ala Gly Pro Ala Phe Gln 565 570 575 Val Ile Lys Asp Ser Leu Thr Leu Gly Leu Asn Ala Leu Thr Leu Thr 580 585 590 Asp Val Thr Lys Asn Ala Ala Tyr Gly Val Glu Ile Glu Ser Leu Val 595 600 605 Leu Glu Ile Asn Ala Pro Ala Ser Ser * 610 615 <210> 363 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19196..19411) <400> 363 Met Tyr Gln Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser 1 5 10 15 Ala Val Gly Thr Gly Tyr Trp Leu Leu Gln Leu Leu Asp Lys Val Ser 20 25 30 Pro Ser Gln Trp Val Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly 35 40 45 Leu Leu Thr Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Lys Glu Asp Arg 50 55 60 Arg Lys Ala Ala Arg Gly Glu * 65 70 <210> 364 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19416..19760) <400> 364 Met Lys Lys Lys Tyr Glu Leu Val Val Lys Gly Ile Asn Asn Tyr Pro 1 5 10 15 Asp Lys Ile Thr Val Thr Val Ala Pro Glu Ile Gly Gly Tyr Pro Ser 20 25 30 Leu Leu Leu Pro Asp Val Ala Ile Ser Leu Asp Arg Thr Glu Gly Ala 35 40 45 Thr Leu Glu Phe Tyr Glu Ala Glu Ala Lys Lys Gln Ala Lys Gln Phe 50 55 60 Phe Met Asp Val Ala Ala Gly Leu Cys Glu Gly Asp Gly Pro Leu Pro 65 70 75 80 Glu Lys Arg Pro Val Ile Leu Glu Ala Gln Asp Val Leu Ile Thr Tyr 85 90 95 Arg Gly Lys Leu Pro Gly Ile Ile Thr Gly Ser Leu Lys Thr Pro Pro 100 105 110 Leu Ala * <210> 365 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19811..20344) <400> 365 Met Asn Ala Lys Ile Arg Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Gly Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Thr Arg Gly Asp Gly Lys Pro Val Ile 50 55 60 Pro Gly Met Lys Leu Ser Lys Glu Lys Cys Asp Arg Val Asn Ala Ile 65 70 75 80 Glu Arg Asp Lys Ala Leu Ala Trp Val Glu Lys Asn Ile Arg Val Pro 85 90 95 Leu Thr Glu Pro Gln Lys Ala Gly Ile Ala Ser Phe Cys Pro Tyr Asn 100 105 110 Ile Gly Pro Gly Lys Cys Phe Pro Ser Thr Phe Tyr Arg Arg Ile Asn 115 120 125 Ala Gly Asp Arg Lys Gly Ala Cys Glu Ala Ile Arg Trp Trp Ile Lys 130 135 140 Asp Gly Gly Arg Asp Cys Arg Ile Arg Ser Asn Asn Cys Tyr Gly Gln 145 150 155 160 Val Ser Arg Arg Asp Gln Glu Ser Ala Leu Ala Cys Trp Gly Ile Asp 165 170 175 Arg * <210> 366 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20615..21184) <400> 366 Met Asn Met Met Ala Val Pro Phe His Gly Asn Ser Leu Tyr Val Val 1 5 10 15 Asn His Asn Gly Glu Pro Tyr Val Pro Met Lys Pro Val Val Ala Gly 20 25 30 Met Gly Leu Ala Trp Gln Ser Gln Leu Ala Lys Leu Arg Gln Arg Phe 35 40 45 Ala Ser Thr Ile Thr Glu Ile Val Met Val Ala Glu Asp Gly Lys Gln 50 55 60 Arg Asn Met Val Ser Met Pro Leu Arg Lys Leu Ala Gly Trp Leu Gln 65 70 75 80 Thr Ile Asn Pro Asn Lys Val Lys Pro Glu Ile Arg Asp Lys Val Ile 85 90 95 Arg Tyr Gln Glu Glu Cys Asp Asp Val Leu Tyr Glu Tyr Trp Thr Lys 100 105 110 Gly Phe Val Val Asn Pro Arg Lys Met Ser Val Met Glu Glu Leu Asn 115 120 125 Gln Ala Cys Ala Asp Met Lys Arg Asp Lys Asn Ile Ala Ser Val Phe 130 135 140 Ala Thr Gly Leu Asn Glu Trp Lys Gln Val Lys Ala Ala His Val Ser 145 150 155 160 Lys Ile Arg Thr Leu Val Asn Glu Ala Asn Met Leu Ile Asp Phe Val 165 170 175 Leu Ala Asp Thr Gly Lys Gly Lys Ile Thr Lys Ala Asp * 180 185 <210> 367 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21338..21805) <400> 367 Met Asn Arg Val Leu Cys Val Val Ile Ile Val Leu Ala Val Gly Tyr 1 5 10 15 Gly Ala Leu Trp Leu Ala Thr Asn His Tyr Arg Asp Asn Ala Leu Thr 20 25 30 Tyr Lys Ala Gln Arg Asp Lys Lys Ala Arg Glu Leu Glu Gln Ala Asn 35 40 45 Ala Thr Ile Thr Asp Met Gln Val Arg Gln Arg Asp Val Ala Ala Leu 50 55 60 Asp Ala Lys Tyr Ser Arg Glu Leu Ala Asp Ala Arg Ala Glu Asn Glu 65 70 75 80 Thr Leu Arg Ala Asp Val Ala Ala Gly Arg Lys Arg Leu Arg Ile Asn 85 90 95 Ala Thr Cys Ser Gly Thr Val Arg Glu Ala Thr Gly Thr Ser Gly Val 100 105 110 Asp Asn Ala Thr Gly Pro Arg Leu Ala Asp Thr Ala Glu Arg Asp Tyr 115 120 125 Phe Ile Leu Arg Glu Arg Leu Met Thr Met Gln Lys Gln Leu Glu Gly 130 135 140 Ala Gln Asp Tyr Ile Arg Thr Gln Cys Leu Asn * 145 150 155 <210> 368 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21558..21743) <400> 368 Met Arg Glu Leu Lys Met Lys Leu Cys Val Leu Met Leu Pro Leu Val 1 5 10 15 Val Ser Ala Cys Gly Ser Thr Pro Pro Ala Pro Val Pro Cys Val Lys 20 25 30 Pro Pro Ala Pro Pro Ala Trp Ile Met Gln Pro Ala Pro Asp Trp Gln 35 40 45 Thr Pro Leu Asn Gly Ile Ile Ser Ser Ser Glu Asn Gly * 50 55 60 <210> 369 <211> 76 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22168..22395) <400> 369 Met Ser Ser Lys Asn Arg Pro Arg Arg Thr Thr Thr Arg Asn Ile Arg 1 5 10 15 Phe Pro Asn Gln Met Ile Glu Gln Ile Asn Ile Ala Leu Asp Gln Lys 20 25 30 Gly Ser Glu Asn Phe Ser Ala Trp Val Ile Glu Ser Cys Arg Arg Glu 35 40 45 Leu Ala Ala Asp Ile Lys Tyr Ala Arg Gln Leu Thr Ile Lys Lys Asn 50 55 60 Asp Thr Gln Tyr Ala Leu Arg Trp Leu Phe Ile * 65 70 75 <210> 370 <211> 122 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22437..22802) <400> 370 Met Ala Val Leu Arg Thr Leu Pro Gly Arg Ile Lys Thr Leu Asn Thr 1 5 10 15 Arg Arg Ile Asn Val Leu Arg Gly Glu Gln Arg Arg Val Ser Gly Ser 20 25 30 Ala Arg Val Ser Leu Lys Arg Arg Ile Trp Arg Arg Asp Ala Gly His 35 40 45 Cys Cys Leu Cys Arg Arg Val Val Asp Leu Cys Asp Ser Glu Leu Asp 50 55 60 His Arg Ile Ala Leu Gln Phe Gly Gly Gly Asn Glu Glu Thr Asn Leu 65 70 75 80 Trp Thr Leu Cys Thr Glu Cys His Arg Gln Lys Ser Ala Ser Glu Ala 85 90 95 Ala Ser Gly Met Pro Asp Pro Thr Leu Pro Glu Leu Pro Asp Gly Thr 100 105 110 Leu Arg Ala Asp Gly Ile Thr Gly Leu * 115 120 <210> 371 <211> 48 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22765..22908) <400> 371 Met Ala Arg Ser Gly Pro Thr Glu Ser Leu Ala Cys Asp Gln Thr Arg 1 5 10 15 Gly Gly Ser Ser Gly Glu Lys Lys Arg Ser Pro Trp Thr Pro Arg Pro 20 25 30 Leu Ser Arg Arg Glu Lys Ile Pro Val Ser Gly Gln Leu Thr Cys * 35 40 45 <210> 372 <211> 188 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23092..23655) <400> 372 Val Leu Thr Thr Gln Lys Arg Lys Phe Ala Leu Ala Leu Met Ser Gly 1 5 10 15 Lys Asn Lys Thr Ala Ser Ala Leu Ala Ala Gly Tyr Ser Ala Lys Thr 20 25 30 Ala Arg Val Lys Gly Ser Gln Leu Ala Lys Asp Pro Glu Val Leu Ala 35 40 45 Phe Ile Ala Arg Lys Gln Cys Glu Thr Val Glu Val Asp Glu Val Pro 50 55 60 Val Tyr Arg Gln Lys Lys Ser Glu Pro Glu Asp Lys Pro Arg Arg Arg 65 70 75 80 Glu Ala Ala Ala Ile Pro Gln Pro Asp Glu Thr Asn Pro Glu Met Pro 85 90 95 Pro Pro Val Val Ile Ser Pro Gly Ile Glu Tyr Met Glu Asp Gly Leu 100 105 110 Pro Asp Pro Val Lys Ala Met Gly Arg Leu Leu Val Glu Asn Ile Asn 115 120 125 Thr Asp Pro Arg Leu Ala Leu Asp Ala Ala Tyr Lys Leu Ala Gln Phe 130 135 140 Thr His His Lys Lys Gly Asp Ala Gly Lys Lys Ser Ala Lys Gly Asp 145 150 155 160 Ala Ala Lys Lys Ala Ala Asn Arg Phe Ala Val Pro Pro Pro Pro Arg 165 170 175 Leu Val Val Asn Asn Asp Asn Glu Gly Asn Gly * 180 185 <210> 373 <211> 554 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23652..25313) <400> 373 Met Ile Pro Val Trp Ser Thr Ala Cys Pro Asp Trp Ala Glu Arg Leu 1 5 10 15 Lys Lys Gly Leu Ser Ile Ile Pro Ala Pro Ile Tyr Pro Glu Gln Ala 20 25 30 Ala His Ala Leu Ala Ile Phe Lys Gln Leu Arg Ile Val Asp Ala Pro 35 40 45 Gly Ser Pro Thr Phe Gly Glu Ser Cys Ala Gln Trp Val Phe Asp Leu 50 55 60 Val Ala Ala Leu Phe Gly Ser Tyr Asp Ala Gln Thr Gly Val Arg His 65 70 75 80 Ile Lys Glu Val Phe Ile Leu Ile Pro Lys Lys Asn Ser Lys Ser Thr 85 90 95 Leu Ala Ala Gly Ile Met Met Thr Ala Leu Leu Leu Asn Trp Arg Gln 100 105 110 Ala Ala Gly Tyr Thr Ile Leu Ala Pro Thr Val Glu Val Ala Ala Asn 115 120 125 Ala Phe Asn Pro Ala Arg Asp Met Val Arg Arg Asp Asp Asp Leu Asp 130 135 140 Asp Leu Cys Gln Val Gln Thr His Ile Arg Thr Ile Thr His Arg Val 145 150 155 160 Thr Asp Thr Thr Leu Lys Val Val Ala Ala Asp Pro Asn Thr Val Ser 165 170 175 Gly Ile Lys Ser Val Gly Thr Leu Ile Asp Glu Leu Trp Leu Phe Gly 180 185 190 Lys Gln Tyr Lys Ala Glu Asp Met Leu Arg Glu Ala Ile Gly Gly Leu 195 200 205 Ala Ser Arg Pro Glu Gly Phe Val Val Tyr Thr Thr Thr Gln Ser Asn 210 215 220 Glu Pro Pro Ala Gly Val Phe Arg Gln Lys Leu Gln Tyr Ala Arg Asp 225 230 235 240 Val Arg Asp Gly Lys Ile His Asp Pro His Phe Leu Pro Val Ile Phe 245 250 255 Glu His Pro Pro Glu Met Val Glu Ser Gly Ala His Leu Leu Met Glu 260 265 270 Asn Leu Ala Met Val Asn Pro Asn Leu Gly Tyr Ser Val Asp Glu Ala 275 280 285 Phe Leu Tyr Arg Glu Tyr Arg Lys Ala Arg Glu Ala Gly Glu Glu Ala 290 295 300 Phe Arg Gly Phe Met Ser Lys His Ala Asn Val Glu Ile Gly Leu Ala 305 310 315 320 Leu Arg Ser Asp Arg Trp Ala Gly Ala Asp Phe Trp Glu Gln Gln Gly 325 330 335 Arg Arg Val Ser Leu Asp Asp Ile Leu Gln Arg Ala Asp Val Val Thr 340 345 350 Val Gly Ile Asp Gly Gly Gly Leu Asp Asp Leu Leu Gly Met Tyr Val 355 360 365 Ile Gly Arg Asp Arg Glu Thr Arg Glu Trp Leu Gly Trp Gly His Ala 370 375 380 Trp Ala His Glu Thr Ala Val Val Arg Arg Lys Ser Glu Ala Ser Arg 385 390 395 400 Phe Gln Asp Leu Val Ala Cys Gly Asp Met Thr Ile Val Arg Arg Val 405 410 415 Gly Asp Asp Thr Ala Glu Val Ala Glu Tyr Val Arg Arg Ile His Glu 420 425 430 Ala Glu Leu Leu Asp His Ile Gly Ile Asp Pro Ser Gly Val Gly Gln 435 440 445 Ile Leu Asp Ser Leu Ala Glu Ala Gly Ile Pro Asp Gly Ile Val Val 450 455 460 Gly Ile Ser Gln Gly Trp Lys Leu Gly Gly Ala Ile Lys Thr Thr Glu 465 470 475 480 Arg Lys Leu Ala Glu Gly Val Leu Val His Gly Asp Gln Pro Leu Met 485 490 495 Ala Trp Cys Val Gly Asn Ala Arg Val Glu Pro Lys Gly Asn Ala Ile 500 505 510 Leu Ile Thr Lys Gln Ala Ser Gly Arg Gly Lys Ile Asp Pro Leu Met 515 520 525 Ala Leu Phe Asn Ala Val Ser Leu Met Ser Leu Asn Pro Glu Pro Lys 530 535 540 Lys Lys Glu Tyr Ala Val Phe Phe Ile * 545 550 <210> 374 <211> 646 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25377..27314) <400> 374 Val Thr Leu Lys Arg Ala Cys Ser Leu Leu Thr Val Lys Ser Phe Ser 1 5 10 15 Glu Asp Glu Arg Val Ile Thr Gly Ile Ala Ser Thr Pro Ser Pro Asp 20 25 30 Arg Asp Gly Asp Ile Leu Glu Pro Glu Gly Ala Glu Phe Gly Ser Ala 35 40 45 Ile Pro Phe Leu Trp Gln His Asp His Ser Arg Pro Val Gly Gln Cys 50 55 60 Thr Val Arg Arg Val Ser Glu Gly Leu Glu Ile Thr Ala Thr Leu Val 65 70 75 80 Lys Pro Val Pro Asp Met Pro Ser Gln Leu Ala Ala Arg Leu Asp Glu 85 90 95 Val Trp Ala Ala Ile Lys Thr Gly Leu Val Arg Gly Leu Ser Val Gly 100 105 110 Phe Arg Pro His Glu Tyr Thr Phe Leu Asp Gly Gly Gly Leu His Phe 115 120 125 Leu Arg Trp Glu Leu Met Glu Val Ser Ala Val Thr Val Pro Ala Asn 130 135 140 Ala Glu Cys Thr Ile Arg Thr Ile Lys Ser Tyr Asp Arg Pro Phe Ser 145 150 155 160 Ala Ala Ser Gly Asn Arg Lys Pro Val Val Lys Ile Ala Ser Ser Ala 165 170 175 Gly Ala Ala Ala Gln Ser Thr Thr Val Phe His Lys Glu Lys Thr Ile 180 185 190 Met Asn Ile Gly Glu Gln Ile Lys Ser Phe Glu Asn Lys Arg Ala Ala 195 200 205 Leu Ala Ala Ser Leu Glu Glu Val Met Thr Lys Ala Ala Glu Glu Gly 210 215 220 Arg Thr Leu Asp Val Glu Glu Glu Glu His Tyr Asp Asn Thr Ala Ala 225 230 235 240 Glu Ile Arg Gln Val Asp Ala His Leu Lys Arg Leu Arg Glu Leu Glu 245 250 255 Ala Gly Lys Ala Ala Thr Ala Gln Pro Val Lys Gln Ala Gly Asn Gly 260 265 270 Asn Val Ala Ala Val Ala Ser Ala Pro Val Ile Arg Val Glu Gln Lys 275 280 285 Leu Asp Lys Gly Ile Gly Phe Ala Arg Phe Ala Lys Ser Leu Ala Ala 290 295 300 Ala Lys Gly Val Arg Ser Glu Ala Leu Glu Val Ala Arg Arg Gln Tyr 305 310 315 320 Pro Asp Asp Ser Arg Leu His His Val Leu Lys Ser Ala Val Gly Ala 325 330 335 Gly Thr Thr Thr Asp Pro Gln Trp Ala Gly Ser Leu Ser Glu Tyr Gln 340 345 350 Glu Tyr Ala Gln Asp Phe Ile Asp Tyr Leu Arg Pro Gln Thr Ile Ile 355 360 365 Gly Arg Phe Gly Gln Gly Gly Ile Pro Ala Leu Arg Gln Val Pro Phe 370 375 380 Asn Ile Arg Val His Ala Gln Val Ser Gly Gly Ala Ala Gly Trp Val 385 390 395 400 Gly Glu Gly Lys Ala Lys Pro Leu Thr Lys Phe Asp Phe Glu Ser Ile 405 410 415 Thr Phe Ser His Ala Lys Val Ser Ala Ile Ala Val Leu Thr Glu Glu 420 425 430 Leu Ile Arg Phe Ser Ser Pro Ala Ala Asp Ala Leu Val Arg Asn Ala 435 440 445 Leu Ala Glu Ala Val Val Ala Arg Leu Asp Thr Asp Phe Val Asp Pro 450 455 460 Lys Lys Ala Ala Val Ala Asp Val Ser Pro Ala Ser Ile Thr His Asp 465 470 475 480 Val Lys Gly Thr Ala Ser Thr Gly Asn Pro Asp Ala Asp Ala Glu Ala 485 490 495 Ala Phe Gly Gln Phe Val Ala Ala Asn Leu Gln Pro Thr Gly Ala Val 500 505 510 Trp Leu Met Ser Ser Thr Asn Ala Leu Ala Leu Ser Met Arg Lys Asn 515 520 525 Ala Leu Gly Gln Lys Glu Tyr Pro Asp Met Thr Leu Leu Gly Gly Ser 530 535 540 Phe Gln Gly Leu Pro Val Ile Val Ser Gln Tyr Val Gly Asp Gln Leu 545 550 555 560 Val Leu Val Asn Ala Pro Asp Ile Tyr Leu Ala Asp Asp Gly Gly Val 565 570 575 Ala Val Asp Met Ser Arg Glu Ala Ser Leu Glu Met Gln Ser Glu Pro 580 585 590 Gly Gly Asp Ser Thr Thr Pro Ser Pro Val Glu Leu Val Ser Met Phe 595 600 605 Gln Thr Gly Ser Val Ala Ile Arg Ala Glu Arg Trp Ile Asn Trp Arg 610 615 620 Arg Arg Arg Thr Ala Ala Val Ala Val Ile Thr Gly Val Asn Tyr Gly 625 630 635 640 Ser Ala Ser Gly Gly * 645 <210> 375 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27390..27575) <400> 375 Met Met Pro Gly Pro Gly Ile Ser Val Met Trp His Ser Arg Val Arg 1 5 10 15 Arg Cys Trp Phe Ala Trp Gly Arg Arg Ser Thr Ser Gln Arg Asp Val 20 25 30 Arg Gln Val Arg Lys Arg Asn Val Met Arg Ser Met Ala Asn Val Glu 35 40 45 Pro Phe Ala Ala Asn Pro Lys Lys Pro Glu Ile Arg Thr * 50 55 60 <210> 376 <211> 860 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27526..30105) <400> 376 Met Trp Asn Leu Leu Arg Arg Thr Arg Lys Asn Gln Lys Ser Gly Arg 1 5 10 15 Asp Val Arg Glu Val Gly Trp Arg Ser Leu Phe Gln Ala Val Ala Glu 20 25 30 Pro Phe Ala Gly Ala Trp Gln Gln Gly Val Lys Ala Asp Pro Glu Thr 35 40 45 Val Leu Ser Phe His Ala Val Phe Ser Cys Ile Ser Leu Ile Ser Gln 50 55 60 Asp Ile Ala Lys Met Arg Leu Arg Leu Met Gln Thr Asp Val Gln Gly 65 70 75 80 Ile Arg Arg Glu Lys Arg Gln Gly Asp Thr Ala Arg Leu Cys Arg Arg 85 90 95 Pro Asn Ala Gln Gln Asn Arg Ile Gln Phe Phe Glu Leu Trp Leu Asn 100 105 110 Ser Lys Leu Arg His Gly Asn Thr Val Val Leu Lys Ile Arg Thr Pro 115 120 125 Arg Gly Gln Ile Lys Glu Leu Arg Ile Leu Asp Trp Asn Arg Val Glu 130 135 140 Pro Leu Val Ala Asp Asp Gly Glu Val Phe Tyr Arg Ile Thr Pro Asp 145 150 155 160 Arg Asn Cys Gly Ile Thr Glu Ser Val Thr Val Pro Ala Arg Glu Val 165 170 175 Ile His Asp Arg Phe Asn Cys Phe Phe His Pro Leu Val Gly Leu Pro 180 185 190 Pro Val Tyr Ala Ala Gly Leu Ala Ala Met Gln Gly His His Ile Gln 195 200 205 Ala Asn Ser Thr Tyr Phe Phe Arg Asn Gly Gly Arg Pro Ser Gly Val 210 215 220 Ile Glu Val Pro Gly Ser Ile Thr Glu Glu Asn Ala Lys Lys Leu Lys 225 230 235 240 Gly Asn Trp Asp Ser Gly Tyr Thr Gly Glu Asn Ala Gly Lys Thr Ala 245 250 255 Ile Leu Ser Asn Gly Ala Lys Tyr Ser Pro Thr Thr Phe Ser Pro Val 260 265 270 Asp Ala Gln Thr Val Glu Gln Leu Lys Met Thr Ala Glu Ile Val Cys 275 280 285 Ser Val Phe Arg Val Pro Ala Tyr Lys Ile Gly Val Gly His Pro Pro 290 295 300 Ser Ser Asp Asn Val Glu Ala Leu Glu Gln Gln Tyr Tyr Ser Gln Cys 305 310 315 320 Leu Gln Thr Leu Ile Glu Ser Ile Glu Leu Leu Leu Asp Glu Ala Leu 325 330 335 Glu Thr Gly Glu Asn Glu Ser Thr Glu Phe Asp Val Thr Thr Leu Leu 340 345 350 Arg Met Asp Ser Glu Arg Arg Met Lys Thr Leu Gly Asp Ala Val Lys 355 360 365 Asn Thr Leu Leu Thr Pro Asn Glu Ala Arg Lys Arg Glu Asn Leu Pro 370 375 380 Pro Leu Ala Gly Gly Asp Ala Leu Tyr Leu Gln Gln Gln Asn Tyr Ser 385 390 395 400 Leu Glu Ala Leu Ser Arg Arg Asp Ala Arg Glu Asp Pro Phe Ala Ser 405 410 415 Ala Gly Lys Thr Val Ser Ser Gln Leu Pro Asp Gly Ala Ser Asp Gly 420 425 430 Asn Lys Ala Ile Ser Glu Thr Glu His Asp Ala Val Lys Ala Met Phe 435 440 445 Arg Gly Asp Thr Glu Lys Met Thr Glu Arg Glu Leu Ser Ile Ile Arg 450 455 460 Ala Leu Gly Glu Glu Phe Ser Thr Val Leu Ala Asp Leu Gln Arg Thr 465 470 475 480 Phe Glu Gly Lys Met Ala Ser Gln Ala Gln Ala Phe Glu Glu Lys Leu 485 490 495 Thr Ser Leu Ser Ala Val Leu Gln Lys His Val Thr Val Asp Glu Val 500 505 510 Arg Pro Val Leu Gln Ala Met Val Asp Asp Ala Val Gly Ala Ile Pro 515 520 525 Val Pro Arg Asp Gly Arg Asp Tyr Asp Pro Asp Val Leu Gln Gln Ala 530 535 540 Val Asn Asp Ala Val Ala Asn Ile Pro Gln Pro Ala Asp Gly Lys Ser 545 550 555 560 Leu Thr Pro Asp Asp Val Arg Pro Met Leu Glu Gln Met Val Lys Glu 565 570 575 Ala Val Ser His Ile Pro Val Pro Arg Asp Gly Arg Asp Tyr Asp Pro 580 585 590 Glu Val Leu Gln Lys Ala Val Asn Asp Ala Val Ala Asn Ile Pro Gln 595 600 605 Pro Ala Asp Gly Lys Ser Leu Thr Pro Asp Asp Val Arg Pro Met Leu 610 615 620 Glu Gln Met Val Lys Glu Ala Val Ser His Ile Pro Val Pro Arg Asp 625 630 635 640 Gly Arg Asp Tyr Asp Pro Glu Val Leu Gln Lys Ala Val Asn Asp Ala 645 650 655 Val Ala Asn Ile Pro Gln Pro Ala Asp Gly Lys Ser Leu Thr Pro Asp 660 665 670 Asp Val Arg Pro Met Leu Glu Gln Met Val Lys Glu Ala Val Ser His 675 680 685 Ile Pro Val Pro Arg Asp Gly Arg Asp Tyr Asp Pro Asp Val Leu Gln 690 695 700 Lys Ala Val Leu Asp Ala Val Ser Ala Leu Pro Ala Pro Gln Asp Gly 705 710 715 720 Arg Asp Ala Thr Ala Leu Glu Ile Leu Pro Ala Ile Asp Asp Gln Lys 725 730 735 Ser Phe Pro Arg Gly Thr Tyr Ala Thr His Gln Gly Gly Leu Trp Arg 740 745 750 Ala Tyr Glu Lys Thr His Gly Met Arg Gly Trp Glu Cys Leu Val Asp 755 760 765 Gly Val Ala Asp Ile Asp Val Ser Met Thr Gly Glu Arg Leu Phe Ser 770 775 780 Val Val Val Arg Gln Ser Ser Gly Gln Arg Thr Glu Lys Thr Phe Ser 785 790 795 800 Leu Pro Val Met Leu Tyr Arg Gly Val Phe Arg Ala Gly Glu Thr Tyr 805 810 815 His Pro Gly Asp Thr Val Thr Trp Gly Gly Ser Leu Trp His Cys Asn 820 825 830 Ser Met Thr Glu Asp Lys Pro Gly Glu Ala His Ser Ser Ala Trp Thr 835 840 845 Leu Ala Ala Lys Arg Gly Arg Asp Ala Gly Gly * 850 855 <210> 377 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30108..30434) <400> 377 Met Thr Ala Leu Leu Thr Leu Glu Glu Ile Lys Ala His Leu Arg Val 1 5 10 15 Asp His Asp Ala Asp Asp Asp Met Leu Met Asp Lys Val Arg Gln Ala 20 25 30 Thr Ala Val Leu Leu Ala Tyr Ile Gln Gly Ser Arg Asp Lys Val Ile 35 40 45 Arg Glu Asp Gly Glu Leu Ile Pro Gly Glu Ala Leu Thr Arg Met Lys 50 55 60 Gly Ala Ala Met Arg Leu Thr Gly Met Leu Tyr Arg Asn Pro Asp Leu 65 70 75 80 Ala Glu Arg Glu Glu Leu Ile Gln Gly Glu Leu Pro Phe Ser Val Ser 85 90 95 Val Leu Ile Tyr Asp Leu Arg Cys Pro Thr Val Leu * 100 105 <210> 378 <211> 117 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30444..30794) <400> 378 Met Ala Ile Ser Ala Gly Arg Leu Thr Gln Met Ile Ser Val Leu Asn 1 5 10 15 Pro Val Leu Thr Arg Asn Ala Ala Gly Glu Met Thr Glu Glu Trp Val 20 25 30 Ser Cys Gly Lys Ile His Ala Asp Ile Arg Gly Arg Ser Ser Arg Glu 35 40 45 Arg Met Gln Ser Gly Ala Glu Met Ala Gln Ala Glu Ile Arg Ile Trp 50 55 60 Val Arg Gly Gln Ser Gly Arg Glu Ile Thr Ala Ala Ser Arg Leu His 65 70 75 80 Val Leu Ser Gly Pro Trp Arg Asp Arg Ile Leu Asn Val Val Gly Leu 85 90 95 Pro Val Pro Asp Ala Thr Gly Gly Arg Leu Glu Ile Leu Cys Arg Leu 100 105 110 Gly Gly Glu Lys * 115 <210> 379 <211> 149 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30791..31237) <400> 379 Met Ile Glu Thr Leu Leu Asp Phe Ser Gly Leu Glu Asp Ile Ser Arg 1 5 10 15 Asp Leu Gln Leu Leu Ser Gly Ala Glu Asn Asn Arg Val Leu Arg Glu 20 25 30 Ala Thr Arg Ala Gly Ala Asn Val Leu Lys Glu Glu Val Val Ser Arg 35 40 45 Ala Pro Val Arg Arg Gly Lys Leu Arg Arg Asn Val Val Val Leu Ser 50 55 60 Arg Arg Ser Arg Asp Gly Gly Met Glu Ser Gly Val His Ile Arg Gly 65 70 75 80 Val Asn Pro Asp Thr Gly Asn Ser Asp Asn Thr Met Lys Ala Asp Asn 85 90 95 Pro Arg Asn Ala Phe Tyr Trp Arg Phe Val Glu Met Gly Thr Val Asn 100 105 110 Met Pro Pro His Pro Phe Val Arg Pro Ala Phe Asp Val Arg Ser Glu 115 120 125 Gln Ala Ala Gln Val Ala Ile Ala Arg Met Asn Arg Ala Ile Asp Glu 130 135 140 Val Leu Arg Arg * 145 <210> 380 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31234..31578) <400> 380 Met Thr Glu Ala Asp Leu Tyr Pro His Leu Ala His Leu Ala Gly Gly 1 5 10 15 Gln Val Tyr Pro Tyr Val Val Pro Leu Leu Asp Gly Arg Pro Ser Val 20 25 30 Ala Leu Pro Trp Val Val Phe Ser Leu Ile Ser Ser Val Ser Ala Asp 35 40 45 Val Met Gly Gly Gln Ala Glu Ser Ser Val Ser Val Gln Ile Asp Val 50 55 60 Tyr Ala Gly Thr Val Thr Gln Ala Arg Gln Ile Arg Gln Asp Ala Arg 65 70 75 80 Glu Ala Ile Met Leu Leu Ala Pro Gly Ser Val Ser Glu Met Gln Asp 85 90 95 Tyr Ile Pro Glu Asn Arg Cys Tyr Arg Ala Thr Leu Glu Phe Gln Val 100 105 110 Thr Val * <210> 381 <211> 282 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31508..32353) <400> 381 Val Lys Cys Arg Thr Ile Phe Arg Lys Thr Ala Val Thr Val Gln Pro 1 5 10 15 Trp Ser Phe Arg Ser Arg Cys Asn Phe Phe Asn Arg Thr His Asn Pro 20 25 30 Pro Arg Ala Gly Phe Leu Leu Ser Gly Gly Arg Met Ser Ala Leu Tyr 35 40 45 Glu Arg Ser Gln Leu Thr Gln Val Met Ile Ser Ser Ala Pro Ala Thr 50 55 60 Ala Glu Thr Met Glu Lys Ala Glu Tyr Leu Arg Leu Asp Cys Thr Ile 65 70 75 80 Lys Glu Val Gln Phe Thr Ala Gly Gln Lys Gln Asp Ile Asp Val Thr 85 90 95 Thr Leu Cys Ser Thr Glu Gln Glu Asn Ile Asn Gly Leu Gly Ala Ser 100 105 110 Ser Glu Ile Ser Met Ser Gly Asn Phe Tyr Leu Asn Gln Ala Gln Asn 115 120 125 Ala Leu Arg Asp Ala Tyr Asp Asn Asp Ala Leu Tyr Ala Phe Lys Val 130 135 140 Leu Phe Pro Ser Gly Lys Gly Phe Lys Phe Leu Ala Glu Val Arg Gln 145 150 155 160 His Thr Trp Ser Ser Gly Thr Asn Gly Val Val Ala Ala Thr Phe Ser 165 170 175 Leu Arg Leu Lys Gly Lys Pro Val Ser Phe Val Val Pro Leu Ala Phe 180 185 190 Val Lys Asn Pro Asp Lys Thr Leu Thr Val Asn Thr Gly Ala Leu Leu 195 200 205 Thr Met Ser Val Ser Val Asn Gly Gly Thr Pro Pro Tyr Lys His Ala 210 215 220 Trp Lys Lys Asp Gly Gln Pro Val Glu Gly Gln Thr Thr Asp Thr Phe 225 230 235 240 Ser Lys Ala Asn Thr Gln Ser Gly Asp Lys Gly Ala Tyr Thr Cys Glu 245 250 255 Val Thr Asp Ser Ala Glu Gln Pro Gln Ser Ile Thr Ser Asp Ala Cys 260 265 270 Thr Val Thr Val Asn Gly Ala Gly Gly * 275 280 <210> 382 <211> 125 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32359..32733) <400> 382 Met Ala Lys Asp Leu Lys Thr Leu Ala Leu Ala Arg Leu Ser Gly Phe 1 5 10 15 Arg His Lys Thr Val Lys Val Pro Glu Trp Arg Asn Val Ser Val Val 20 25 30 Leu Arg Glu Pro Ser Ala Glu Ala Trp Tyr Leu Trp Gln Glu Val Leu 35 40 45 Asn Gly Asp Gly Glu Asp Asp Asp Thr Leu Ser Val Val Ala Lys Thr 50 55 60 Arg Arg Asn Leu Glu Ala Asp Val Thr Leu Phe Cys Asp Val Leu Cys 65 70 75 80 Asp Thr Asp Leu Gln Arg Val Phe Thr Pro Asp Asp Arg Glu Gln Val 85 90 95 Leu Ala Val Tyr Gly Pro Val His Ala Arg Leu Leu Arg Gln Ala Leu 100 105 110 Glu Leu Ile Ala Asp Ala Glu Ser Ala Arg Lys Lys * 115 120 <210> 383 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32757..33038) <400> 383 Met Arg Leu Ala Leu Arg Leu Gly Arg Thr Leu Ser Glu Leu Arg His 1 5 10 15 Ser Leu Ser Ala Ser Glu Ala Met Met Trp Met Glu Phe Asp Arg Val 20 25 30 Ser Pro Leu Gly Asp Glu Arg Gly Asp Ile Arg Asn Ala Gln Ile Val 35 40 45 Lys Ala Val Phe Gly Ala Gln Gly Met Asn Val Ala Leu Lys Asp Ala 50 55 60 Met Leu Cys Trp Gly Glu Asp Glu Asp Lys Pro Glu Val Asp Pro Phe 65 70 75 80 Ala Ala Leu Glu Asp Ala Leu Ser Leu Ala Ala Met Ser * 85 90 <210> 384 <211> 1027 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33091..36171) <400> 384 Met Ala Thr Leu Arg Glu Leu Ile Ile Lys Ile Ser Ala Asn Ser Gln 1 5 10 15 Ser Phe Gln Ser Glu Ile Gln Arg Ala Ser Arg Met Gly Ser Glu Tyr 20 25 30 Tyr Arg Thr Leu Gln Asn Gly Gly Arg Gln Ala Ala Ala Ala Ala Arg 35 40 45 Glu Gln Arg Arg Ala Leu Ala Glu Leu Asn Ser Gln Leu Thr Glu Ile 50 55 60 Arg Gly Ser Ala Val Gly Met Ala Gly Ala Phe Ala Gly Ala Phe Ala 65 70 75 80 Ser Gly His Leu Ile Ser Leu Ala Asp Glu Trp Ser Ser Val Asn Ala 85 90 95 Arg Leu Lys Gln Ala Ser Gln Ser Ser Asp Glu Phe Ala Ser Ser Gln 100 105 110 Lys Val Leu Met Asp Ile Ser Gln Arg Thr Gly Thr Ala Phe Ser Asp 115 120 125 Asn Ala Ala Leu Phe Ala Arg Ser Ala Ala Ser Met Arg Glu Tyr Gly 130 135 140 Tyr Ser Ala Gly Asp Val Leu Lys Val Thr Glu Ala Ile Ser Thr Gly 145 150 155 160 Leu Lys Ile Ser Gly Ala Ser Thr Ala Glu Ala Gly Ser Val Ile Thr 165 170 175 Gln Phe Ser Gln Ala Leu Ala Gln Gly Val Leu Arg Gly Glu Glu Phe 180 185 190 Asn Ser Val Asn Glu Ser Gly Asp Arg Ile Val Arg Ala Leu Ala Ala 195 200 205 Gly Met Gly Val Ala Arg Lys Asp Leu Lys Ala Met Ala Asp Asp Gly 210 215 220 Lys Leu Thr Ala Asp Lys Val Val Pro Ala Leu Ile Ser Gln Leu Gly 225 230 235 240 Ile Leu Arg Asp Glu Tyr Ala Ala Met Pro Glu Thr Val Ser Ser Ser 245 250 255 Ile Thr Lys Val Glu Asn Ala Phe Met Ala Trp Val Gly Gly Ala Asn 260 265 270 Glu Ala Ser Gly Val Thr Lys Thr Leu Ser Gly Met Leu Asn Gly Val 275 280 285 Ala Gly Gln Ile Asp Asn Val Ala Thr Ala Val Gly Ala Leu Val Ala 290 295 300 Val Gly Val Ala Arg Tyr Phe Gly Asn Met Ala Ser Gly Ala Met Ser 305 310 315 320 Ala Thr Ala Gly Leu Val Thr Ala Ala Arg Asn Glu Val Ala Leu Ala 325 330 335 Glu Ala Gln Phe Arg Gly Thr Gln Ile Ala Thr Ala Arg Ala Arg Ala 340 345 350 Ala Val Tyr Arg Ala Gln Gln Ala Val Ala Ala Ala Arg Gly Thr Glu 355 360 365 Met Gln Ile Ala Ala Glu Ala Arg Leu Ala Ala Thr Gln Glu Arg Leu 370 375 380 Asn Arg Asn Ile Ala Ala Arg Ser Ala Ala Gln Asn Ala Leu Asn Ser 385 390 395 400 Thr Thr Ala Val Gly Ser Arg Leu Met Ser Gly Ala Leu Gly Leu Val 405 410 415 Gly Gly Val Pro Gly Leu Val Met Leu Gly Ala Ala Ala Trp Tyr Thr 420 425 430 Leu Tyr Gln Asn Gln Glu Gln Ala Arg Glu Ser Ala Arg Gln Tyr Ala 435 440 445 Leu Thr Ile Asp Glu Ile Ala His Lys Thr Pro Ser Met Ser Leu Pro 450 455 460 Glu Ala Ser Asp Asn Glu Gly Arg Thr Arg Ala Ala Leu Thr Glu Gln 465 470 475 480 Asn Arg Leu Ile Asp Glu Gln Ala Ser Arg Val Lys Ser Leu Gln Glu 485 490 495 Lys Ala Gln Ser Ile Gln Asp Val Leu Ala Gly Leu Glu Asp Arg Arg 500 505 510 Val Ala Leu Ile Arg Gln Gln Ala Ala Glu Gln Asn Lys Val Tyr Gln 515 520 525 Ser Met Leu Val Met Asn Gly Gln His Thr Glu Phe Asn Arg Leu Leu 530 535 540 Gly Leu Gly Asn Glu Leu Leu Gln Gln Arg Gln Gly Leu Val Asn Val 545 550 555 560 Pro Leu Arg Leu Pro Gln Ala Thr Leu Asp Asp Lys Gln Gln Ser Ala 565 570 575 Leu Thr Lys Thr Glu Arg Glu Leu Ala Leu Ser Arg Leu Lys Gly Glu 580 585 590 Glu Lys Glu Arg Val Arg Leu Gly Tyr Ala Ala Asp Asp Leu Gly Phe 595 600 605 Val Gly Asp Pro Tyr Gln Glu Ala Arg Gln Arg Tyr Ile Ser Asn Ala 610 615 620 Leu Glu Ala Trp Arg Asn Asn Glu Ala Asn Lys Pro Lys Ser Arg Gly 625 630 635 640 Gly Lys Ser Glu Thr Glu Lys Ala Glu Asp Ser Phe Ser Arg Leu Leu 645 650 655 Lys Gln Gln Lys Glu Gln Leu Ala Leu Val Gly Gln Asn Thr Glu Leu 660 665 670 Ala Lys Leu Lys Tyr Gln Thr Ala Leu Gly Glu Leu Lys Thr Leu Thr 675 680 685 Glu Met Gln Lys Gln Glu Leu Leu Arg Asn Ala Thr Leu Ile Asp Gln 690 695 700 Gln Lys Ile Arg Glu Gln Leu Arg Ser Arg Glu Glu Thr Leu Lys Asn 705 710 715 720 Glu Asn Ala Ala Ala Arg Ala Ser Asn Asp Ala Glu Leu Leu Gly Tyr 725 730 735 Gly Gln Gly Glu Arg Ala Arg Glu Arg Met Arg Glu Leu Gln Gln Ile 740 745 750 Arg Asp Ser Phe Arg Gln Lys Asp Ala Asp Leu Gln Ser Gln Tyr Gln 755 760 765 Thr Gly Asp Ile Ser Glu Asp Phe Tyr Arg Gln Ala Leu Ala Gln Asn 770 775 780 Ala Gln Tyr Leu Ser Glu Arg Leu Lys Asp Gln Ala Val Phe Tyr Ala 785 790 795 800 Glu Ser Asp Val Gln Arg Ala Asp Trp Gln Lys Gly Leu Gln Glu Gly 805 810 815 Phe Ser Asn Trp Val Asp Asn Ala Ser Asp Tyr Ala Ser Gln Ala Ala 820 825 830 Gln Leu Ala Thr Glu Gly Ile Ser Gly Met Val Asn Asn Ile Thr Glu 835 840 845 Met Leu Asn Gly Asn Lys Val Glu Trp Arg Ser Trp Ala Ser Ser Val 850 855 860 Leu Gln Glu Ile Ser Lys Val Leu Met Asn Ala Ala Ile Val Asn Gly 865 870 875 880 Ile Lys Thr Ala Ala Asn Gly Met Ser Gly Ala Gly Gly Phe Leu Gly 885 890 895 Ser Ile Gly Asp Trp Leu Gly Gly Ala Val Ala Asn Ala Lys Gly Gly 900 905 910 Val Tyr Thr Ser Ala Asn Leu Ser Ala Tyr Ser Asn Ser Ile Val Asp 915 920 925 Thr Pro Thr Tyr Phe Ala Phe Ala Lys Gly Ala Gly Leu Met Gly Glu 930 935 940 Ala Gly Pro Glu Ala Ile Met Pro Leu Thr Arg Ala Ala Asp Gly Ser 945 950 955 960 Leu Gly Val Arg Ala Val Gly Ser Met Asn Gly Ser Ala Gly Leu Val 965 970 975 Tyr Ser Pro Val Tyr His Ile Ala Ile Gln Asn Asp Gly Ala Asn Gly 980 985 990 Gln Ile Gly Pro Glu Ala Ala Gly Ser Leu Val Gln Leu Ile Asp Gln 995 1000 1005 Arg Val Gln Ala Val Met Leu Ser Met Arg Arg Asp Gly Gly Met Leu 1010 1015 1020 Ser Gly * 1025 <210> 385 <211> 114 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36164..36505) <400> 385 Val Ala Glu Ile Lys Thr Leu His Leu Val Pro Arg Glu Gly Met Gln 1 5 10 15 Val Ser Glu Lys Pro Ser Val Val Arg Val Arg Phe Gly Asp Gly Tyr 20 25 30 Glu Gln Arg Arg Pro Thr Gly Leu Asn Pro Gln Leu Lys Thr Phe Gln 35 40 45 Ala Val Phe Arg Val Thr Asp Glu Ser Thr Arg Arg Trp Leu Asp Glu 50 55 60 Phe Leu Ser Trp His Gly Gly Tyr Arg Ala Phe Leu Trp Arg Pro Pro 65 70 75 80 Lys His Asn Arg Thr Val Arg Val Val Cys Arg Glu Trp Ser Val Thr 85 90 95 Asp Asn Ala Arg Tyr Ser Asp Phe Ser Cys Thr Ile Glu Gln Val Val 100 105 110 Asn * <210> 386 <211> 146 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36505..36942) <400> 386 Met Gln Asp Ile His Glu Glu Ser Leu Asn Glu Ser Val Lys Ser Glu 1 5 10 15 Gln Ser Pro Arg Val Val Leu Trp Glu Ile Asp Leu Thr Val Gln Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Leu Asn Glu Lys Gly Glu Ala 35 40 45 Val Thr Trp Gln Gly Arg Glu Tyr Gln Ala Tyr Pro Ile Asp Gly Ser 50 55 60 Gly Phe Glu Met Asn Gly Lys Gly Ser Ser Ala Arg Pro Ser Leu Thr 65 70 75 80 Val Ser Asn Leu Phe Gly Leu Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Ala Thr Val Val Arg Arg Arg Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Ala Gly Gly Arg Gly Tyr Arg Ala Ala 115 120 125 Glu Val Lys Arg Ile Lys Lys Ser Arg Arg Val Ala Gly Thr Asp Lys 130 135 140 Asp * 145 <210> 387 <211> 1159 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37130..40606) <400> 387 Met Gly Lys Gly Gly Gly Lys Ala His Thr Pro Val Glu Ala Lys Asp 1 5 10 15 Asn Leu Lys Ser Thr Gln Met Met Ser Val Ile Asp Ala Ile Gly Glu 20 25 30 Gly Pro Ile Glu Gly Pro Val Lys Gly Leu Gln Ser Ile Leu Val Asn 35 40 45 Lys Thr Pro Leu Thr Asp Thr Asp Gly Asn Pro Val Ile His Gly Val 50 55 60 Thr Ala Val Trp Arg Ala Gly Glu Gln Glu Gln Thr Pro Pro Glu Gly 65 70 75 80 Phe Glu Ser Ser Gly Ala Glu Thr Ala Leu Gly Val Glu Val Thr Lys 85 90 95 Ala Lys Pro Val Thr Arg Thr Ile Thr Ser Ala Asn Ile Asp Arg Leu 100 105 110 Arg Val Thr Phe Gly Val Gln Ser Leu Leu Glu Thr Thr Ser Lys Gly 115 120 125 Asp Arg Asn His Ser Ser Val Arg Leu Leu Ile Gln Leu Gln Arg Asn 130 135 140 Gly Asn Trp Val Thr Glu Lys Asp Val Thr Ile Asn Gly Lys Thr Thr 145 150 155 160 Ser Gln Phe Leu Ala Ser Val Ile Leu Asp Asn Leu Pro Pro Arg Pro 165 170 175 Phe Asn Ile Arg Met Val Arg Glu Thr Ala Asp Ser Thr Thr Asp Gln 180 185 190 Leu Gln Asn Arg Thr Leu Trp Ser Ser Tyr Thr Glu Ile Ile Asp Val 195 200 205 Lys Gln Cys Tyr Pro Asn Thr Ala Ile Val Gly Leu Gln Val Asp Ala 210 215 220 Glu Gln Phe Gly Gly Gln Gln Met Thr Val Asn Tyr His Ile Arg Gly 225 230 235 240 Arg Ile Ile Gln Val Pro Ser Asn Tyr Asp Pro Glu Lys Arg Thr Tyr 245 250 255 Ser Gly Ile Trp Asp Gly Ser Leu Lys Pro Ala Tyr Ser Asn Asn Pro 260 265 270 Ala Trp Cys Leu Trp Asp Met Leu Thr His Pro Arg Tyr Gly Met Gly 275 280 285 Lys Arg Leu Gly Ala Ala Asp Val Asp Lys Trp Ala Leu Tyr Ala Ile 290 295 300 Ala Gln Tyr Cys Asp Gln Thr Val Pro Asp Gly Phe Gly Gly Thr Glu 305 310 315 320 Pro Arg Met Thr Phe Asn Ala Tyr Leu Ser Gln Gln Arg Lys Ala Trp 325 330 335 Asp Val Leu Ser Asp Phe Cys Ser Ala Met Arg Cys Met Pro Val Trp 340 345 350 Asn Gly Gln Thr Leu Thr Phe Val Gln Asp Arg Pro Ser Asp Val Val 355 360 365 Trp Pro Tyr Thr Ser Ser Asp Val Val Val Asp Asp Asn Gly Val Gly 370 375 380 Phe Arg Tyr Ser Phe Ser Ala Leu Lys Asp Arg His Thr Ala Val Glu 385 390 395 400 Val Asn Tyr Thr Asp Pro Gln Asn Gly Trp Gln Thr Ser Thr Glu Leu 405 410 415 Val Glu Asp Pro Glu Ala Ile Leu Arg Tyr Gly Arg Asn Leu Leu Lys 420 425 430 Met Asp Ala Phe Gly Cys Thr Ser Arg Gly Gln Ala His Arg Ala Gly 435 440 445 Leu Trp Val Ile Lys Thr Gly Leu Leu Glu Thr Gln Thr Val Asp Phe 450 455 460 Thr Leu Gly Ser Gln Gly Leu Arg His Thr Pro Gly Asp Ile Ile Glu 465 470 475 480 Ile Cys Asp Asn Asp Tyr Ala Gly Thr Met Thr Gly Gly Arg Ile Leu 485 490 495 Ser Ile Asp Ala Ala Ser Arg Thr Leu Thr Leu Asp Arg Glu Val Thr 500 505 510 Leu Pro Glu Thr Gly Ala Ala Thr Val Asn Leu Ile Asn Gly Ser Gly 515 520 525 Lys Pro Val Ser Val Ala Ile Thr Ala His Pro Ala Pro Asp Arg Ile 530 535 540 Gln Val Ser Thr Leu Pro Asp Gly Val Glu Thr Tyr Gly Val Trp Gly 545 550 555 560 Leu Ser Leu Pro Ser Leu Arg Arg Arg Leu Phe Arg Cys Val Ser Val 565 570 575 Arg Glu Asn Thr Asp Gly Thr Phe Ala Ile Thr Ala Val Gln His Val 580 585 590 Pro Glu Lys Glu Ala Ile Val Asp Asn Gly Ala Arg Phe Glu Pro Gln 595 600 605 Ser Gly Thr Leu Asn Ser Val Ile Pro Pro Ala Val Gln His Leu Thr 610 615 620 Val Glu Val Ser Ala Ala Asp Gly Gln Tyr Leu Ala Gln Ala Lys Trp 625 630 635 640 Asp Thr Pro Lys Val Val Lys Gly Val Ser Phe Met Leu Arg Leu Thr 645 650 655 Val Ala Ala Asp Asp Gly Ser Glu Arg Leu Val Ser Thr Ala Arg Thr 660 665 670 Thr Glu Thr Thr Tyr Arg Phe Thr Gln Leu Ala Pro Gly Asn Tyr Arg 675 680 685 Leu Thr Val Arg Ala Val Asn Ala Trp Gly Gln Gln Gly Asp Pro Ala 690 695 700 Ser Val Ser Phe Arg Ile Ala Ala Pro Ala Ala Pro Ser Gln Ile Glu 705 710 715 720 Leu Thr Pro Gly Tyr Phe Gln Ile Thr Ala Val Pro Arg Leu Ala Val 725 730 735 Tyr Asp Pro Thr Val Gln Phe Glu Phe Trp Phe Ser Glu Thr Arg Ile 740 745 750 Thr Asp Ile Arg Gln Val Glu Thr Thr Ala Arg Tyr Leu Gly Thr Gly 755 760 765 Leu Tyr Trp Ile Ala Ala Ser Ile Asn Ile Lys Pro Gly His Asp Tyr 770 775 780 Tyr Phe Tyr Ile Arg Ser Val Asn Thr Val Gly Lys Ser Ala Phe Val 785 790 795 800 Glu Ala Val Gly Gln Pro Ser Asp Asp Ala Ser Gly Tyr Leu Asp Phe 805 810 815 Phe Lys Gly Glu Ile Gly Lys Thr His Leu Ala Gln Glu Leu Trp Thr 820 825 830 Gln Ile Asp Asn Gly Gln Leu Ala Pro Asp Leu Ala Glu Ile Arg Thr 835 840 845 Ser Ile Thr Asp Val Ser Asn Glu Ile Thr Gln Thr Val Asn Lys Lys 850 855 860 Leu Glu Asp Gln Ser Ala Ala Ile Gln Gln Ile Gln Lys Val Gln Val 865 870 875 880 Asp Thr Asn Asn Asn Leu Asn Ser Met Trp Ala Val Lys Leu Gln Gln 885 890 895 Met Gln Asp Gly Arg Leu Tyr Ile Ala Gly Ile Gly Ala Gly Ile Glu 900 905 910 Asn Thr Ser Asp Gly Met Gln Ser Gln Val Leu Leu Ala Ala Asp Arg 915 920 925 Ile Ala Met Ile Asn Pro Ala Asn Gly Asn Thr Lys Pro Met Phe Val 930 935 940 Gly Gln Gly Asp Gln Ile Phe Met Asn Glu Val Phe Leu Lys Tyr Leu 945 950 955 960 Thr Ala Pro Thr Ile Thr Ser Gly Gly Asn Pro Pro Ala Phe Ser Leu 965 970 975 Thr Pro Asp Gly Arg Leu Thr Ala Lys Asn Ala Asp Ile Ser Gly Asn 980 985 990 Val Asn Ala Asn Ser Gly Thr Leu Asn Asn Val Thr Ile Asn Glu Asn 995 1000 1005 Cys Arg Val Leu Gly Lys Leu Ser Ala Asn Gln Ile Glu Gly Asp Leu 1010 1015 1020 Val Lys Thr Val Gly Lys Ala Phe Pro Arg Asp Ser Arg Ala Pro Glu 1025 1030 1035 1040 Arg Trp Pro Ser Gly Thr Ile Thr Val Arg Val Tyr Asp Asp Gln Pro 1045 1050 1055 Phe Asp Arg Gln Ile Val Ile Pro Ala Val Ala Phe Ser Gly Ala Lys 1060 1065 1070 His Glu Lys Glu His Thr Asp Ile Tyr Ser Ser Cys Arg Leu Ile Val 1075 1080 1085 Arg Lys Asn Gly Ala Glu Ile Tyr Asn Arg Thr Ala Leu Asp Asn Thr 1090 1095 1100 Leu Ile Tyr Ser Gly Val Ile Asp Met Pro Ala Gly His Gly His Met 1105 1110 1115 1120 Thr Leu Glu Phe Ser Val Ser Ala Trp Leu Val Asn Asn Trp Tyr Pro 1125 1130 1135 Thr Ala Ser Ile Ser Asp Leu Leu Val Val Val Met Lys Lys Ala Thr 1140 1145 1150 Ala Gly Ile Thr Ile Ser * 1155 <210> 388 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40674..41273) <400> 388 Met Arg Lys Leu Cys Ala Val Ile Leu Ser Ala Val Val Trp Gln Val 1 5 10 15 Ala Ala Ala Thr Pro Ala Ser Ala Ala Glu His Gln Ser Thr Leu Ser 20 25 30 Ala Gly Tyr Leu His Ala Ser Thr Asn Val Pro Gly Ser Asp Asp Leu 35 40 45 Asn Gly Ile Asn Val Lys Tyr Arg Tyr Glu Phe Met Asp Ala Leu Gly 50 55 60 Leu Ile Thr Ser Phe Ser Tyr Ala Asn Ala Glu Asp Glu Gln Lys Thr 65 70 75 80 Arg Tyr Ser Asp Thr Arg Trp His Glu Asp Ser Val Arg Asn Arg Trp 85 90 95 Phe Ser Val Met Ala Gly Pro Ser Val Arg Val Asn Glu Trp Phe Ser 100 105 110 Ala Tyr Ala Met Ala Gly Val Ala Tyr Ser Arg Val Ser Thr Phe Tyr 115 120 125 Gly Asp Tyr Leu Arg Val Thr Asp Asn Lys Gly Lys Thr His Asp Val 130 135 140 Leu Thr Gly Ser Asp Asp Gly Arg His Ser Asn Thr Ser Leu Ala Trp 145 150 155 160 Gly Ala Gly Val Gln Phe Asn Pro Thr Glu Ser Val Thr Ile Asp Leu 165 170 175 Ala Tyr Glu Gly Ser Gly Ser Gly Asp Trp Arg Ser Asp Ala Phe Ile 180 185 190 Val Gly Ile Gly Tyr Arg Phe * 195 <210> 389 <211> 438 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41425..42738) <400> 389 Met Thr Val Lys Ile Ser Gly Val Leu Lys Asp Gly Thr Gly Lys Pro 1 5 10 15 Val Gln Asn Cys Thr Ile Val Leu Lys Ala Arg Arg Thr Ser Ser Thr 20 25 30 Val Val Val Asn Thr Val Ala Ser Glu Asn Pro Asp Glu Ala Gly Arg 35 40 45 Tyr Ser Met Asp Val Glu Tyr Gly Gln Tyr Ser Val Ile Leu Leu Val 50 55 60 Glu Gly Phe Pro Pro Ser His Ala Gly Thr Ile Thr Val Tyr Glu Asp 65 70 75 80 Ser Gln Pro Gly Thr Leu Asn Asp Phe Leu Gly Ala Met Ser Glu Asp 85 90 95 Asp Val Arg Pro Glu Ala Leu Arg Arg Phe Glu Leu Met Val Glu Glu 100 105 110 Ala Ala Arg His Ala Glu Glu Ala Lys Lys Asn Ala Gly Glu Ala Glu 115 120 125 Thr Ser Ala Arg Asn Ala Gly Ile Ser Ala Ser Gln Ala Glu Glu Asn 130 135 140 Ala Ala Asn Ala Asp Thr Ser Ala Gly Asp Ala Ser Glu Ser Ala Arg 145 150 155 160 Gln Ala Ala Glu Ser Ala Ala Ala Ala Lys Gln Ser Glu Glu Ala Ser 165 170 175 Ser Ser Ser Ala Ser Ala Ala Ala Gln Lys Ala Ser Glu Ser Leu Gln 180 185 190 Ser Ala Thr Asp Ala Glu Leu Ser Lys Lys Thr Ala Glu Ser Ala Ala 195 200 205 Gly Asn Ala Ala Arg Asp Ala Thr Thr Ala Ala Glu Lys Ala Arg Glu 210 215 220 Ser Ala Glu Ser Ala Gln Ser Ala Glu Gln Ser Arg Ile Ala Ala Glu 225 230 235 240 Glu Ala Val Asn Arg Ile Pro Thr Val Val Gly Pro Pro Gly Pro Lys 245 250 255 Gly Glu Pro Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp Lys Gly 260 265 270 Glu Arg Gly Asp Thr Gly Pro Ala Gly Ala Thr Gly Glu Arg Gly Pro 275 280 285 Ala Gly Asp Ala Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp Arg 290 295 300 Gly Glu Arg Gly Glu Thr Gly Leu Thr Gly Asn Ala Gly Pro Gln Gly 305 310 315 320 Pro Lys Gly Asp Thr Gly Ala Ala Gly Pro Ala Gly Pro Gln Gly Pro 325 330 335 Lys Gly Glu Thr Gly Ala Ala Gly Pro Val Gly Ala Thr Gly Pro Gln 340 345 350 Gly Pro Lys Gly Asp Pro Gly Glu Thr Gln Ile Arg Phe Arg Leu Gly 355 360 365 Pro Ala Ser Ile Ile Glu Thr Asn Ser His Gly Trp Phe Pro Gly Thr 370 375 380 Asp Gly Ala Leu Ile Thr Gly Leu Thr Phe Leu Ala Pro Lys Asp Thr 385 390 395 400 Thr Arg Val Gln Gly Phe Phe Gln His Leu Gln Val Arg Phe Gly Asp 405 410 415 Gly Pro Trp Gln Asp Val Lys Gly Leu Asp Glu Val Gly Ser Asp Thr 420 425 430 Gly Arg Thr Gly Glu * 435 <210> 390 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42740..43009) <400> 390 Met Asn Ile Leu Lys Lys Leu Met Gln Arg Leu Cys Gly His Gly Lys 1 5 10 15 His Asp Asp Arg Glu Asp Gly Glu Leu Leu Thr Ala Gln Leu Arg Leu 20 25 30 Gly Pro Ala Asp Ile Leu Glu Ser Asp Glu Asn Gly Ile Ile Pro Glu 35 40 45 Gln Asp Arg Val Ile Thr Gln Val Val Ile Leu Asp Ala Asp Lys Lys 50 55 60 Gln Ile Gln Cys Val Val Arg Pro Leu Gln Ile Leu Arg Ala Asp Gly 65 70 75 80 Thr Trp Glu Asn Ile Gly Gly Met Lys * 85 <210> 391 <211> 89 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43224..43490) <400> 391 Met Arg Leu Ser Ala Leu Tyr Leu Met Lys Pro Met Gly Val Phe Tyr 1 5 10 15 Pro Ala Ala Val Val Gly Asp Cys Leu Leu Ser Tyr Ser Phe Met Gly 20 25 30 Leu Ile Thr Ala Leu Lys Leu Phe Ala Ile Gly Cys Ser Val Cys Phe 35 40 45 Arg Thr Gln Val Lys His Asn Arg Lys Arg Val Phe Arg Thr Lys Tyr 50 55 60 Leu Asn Val Ser Phe Leu Leu Val Gln Glu Ile Ser Ser Ala Arg Gln 65 70 75 80 Ser Leu Phe Ser Val Gln Leu His * 85 <210> 392 <211> 112 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43361..43696) <400> 392 Met Leu Ser Asp Ser Gly Glu Ala Gln Ser Gln Glu Ser Ile Gln Asp 1 5 10 15 Lys Ile Ser Gln Cys Lys Phe Pro Val Ser Ser Gly Asn Phe Gln Cys 20 25 30 Pro Pro Glu Ser Ile Gln Cys Pro Ile Thr Leu Glu Arg Pro Glu Glu 35 40 45 Gly Val Phe Val Lys Asn Ser Asp Ser Ser Ala Val Cys Cys Leu Phe 50 55 60 Asp Phe Asp Ala Phe Ser Arg Leu Ala Ser Glu Gly Ser Tyr His Pro 65 70 75 80 Leu Thr Arg Glu Pro Ile Thr Ala Ser Met Ile Ile Ser Pro Asp Lys 85 90 95 Cys Val Tyr Asp Pro Ile Lys Gly Asn Phe Ile Ile Lys Asp Ser * 100 105 110 <210> 393 <211> 442 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44036..45361) <400> 393 Met Asn Ile Gln Pro Thr Ile Gln Ser Gly Ile Thr Ser Gln Asn Asn 1 5 10 15 Gln His His Gln Thr Glu Gln Ile Pro Ser Thr Gln Ile Pro Gln Ser 20 25 30 Glu Leu Pro Leu Gly Cys Gln Ala Gly Phe Val Val Asn Ile Pro Asp 35 40 45 Asp Ile Gln Gln His Ala Pro Glu Cys Gly Glu Thr Thr Ala Leu Leu 50 55 60 Ser Leu Ile Lys Asp Lys Gly Leu Leu Ser Gly Leu Asp Glu Tyr Ile 65 70 75 80 Ala Pro His Leu Glu Glu Gly Ser Ile Gly Lys Lys Thr Leu Asp Met 85 90 95 Phe Gly Leu Phe Asn Val Thr Gln Met Ala Leu Glu Ile Pro Ser Ser 100 105 110 Val Ser Gly Ile Ser Gly Lys Tyr Gly Val Gln Leu Asn Ile Val Lys 115 120 125 Pro Asp Ile His Pro Thr Ser Gly Asn Tyr Phe Leu Gln Ile Phe Pro 130 135 140 Leu His Asp Glu Ile Gly Phe Asn Phe Lys Asp Leu Pro Gly Pro Leu 145 150 155 160 Lys Asn Ala Leu Ser Asn Ser Asn Ile Ser Thr Thr Ala Val Ser Thr 165 170 175 Ile Ala Ser Thr Gly Thr Ser Ala Thr Thr Ser Thr Val Thr Thr Glu 180 185 190 Pro Lys Asp Pro Ile Pro Trp Phe Gly Leu Thr Ala Gln Val Val Arg 195 200 205 Asn His Gly Val Glu Leu Pro Ile Val Lys Thr Glu Asn Gly Trp Lys 210 215 220 Leu Val Gly Glu Thr Pro Leu Thr Pro Asp Gly Pro Lys Ala Asn Tyr 225 230 235 240 Thr Glu Glu Trp Val Ile Arg Pro Gly Glu Ala Asp Phe Lys Tyr Gly 245 250 255 Ala Ser Pro Leu Gln Ala Thr Leu Gly Leu Glu Phe Gly Ala His Phe 260 265 270 Lys Trp Asp Leu Asp Asn Pro Asn Thr Lys Tyr Ala Val Leu Thr Asn 275 280 285 Ala Ala Ala Asn Ala Leu Gly Ala Leu Gly Gly Phe Ala Val Ser Arg 290 295 300 Phe Ala Ser Thr Asp Pro Met Leu Ser Pro His Ile Gly Ala Met Val 305 310 315 320 Gly Gln Ala Ala Gly His Ala Ile Gln Tyr Asn Thr Pro Gly Leu Lys 325 330 335 Pro Asp Thr Ile Leu Trp Trp Ala Gly Ala Thr Leu Gly Ala Ala Asp 340 345 350 Leu Asn Lys Ala Glu Phe Glu Val Ala Arg Phe Thr Asp Tyr Pro Arg 355 360 365 Ile Trp Trp His Ala Arg Glu Gly Ala Ile Phe Pro Asn Lys Ala Asp 370 375 380 Ile Glu His Ala Thr Gly Ala Asp Ile Arg Ala Met Glu Glu Gly Ile 385 390 395 400 Pro Val Gly Gln Arg His Pro Asn Pro Glu Asp Val Val Ile Asp Ile 405 410 415 Glu Ser Asn Gly Leu Pro His His Asn Pro Ser Asn His Val Asp Ile 420 425 430 Phe Asp Ile Ile Gln Glu Thr Arg Val * 435 440 <210> 394 <211> 231 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46022..46714) <400> 394 Met Leu Asn Thr Tyr Val Ala Glu Gly Lys Ala Val Ser Ala Arg Val 1 5 10 15 Ile Arg Ser Thr Leu Val Asp Val Phe Arg Gly Ala Ile Ala Glu Gly 20 25 30 His Val Ala Thr Asn Pro Val Thr Thr Thr Arg Ala Ala Lys Ser Glu 35 40 45 Val Arg Arg Ser Arg Leu Thr Ala Asn Glu Tyr Val Ala Ile Tyr His 50 55 60 Ala Ala Glu His Leu Pro Ile Trp Leu Arg Leu Ser Met Asp Leu Ala 65 70 75 80 Val Val Thr Gly Gln Arg Val Gly Asp Leu Cys Arg Met Lys Trp Ser 85 90 95 Asp Ile Asn Asp Gly His Leu His Ile Gly Gln Ser Lys Thr Gly Ala 100 105 110 Lys Ile Ala Ile Pro Leu Ala Leu Thr Ile Asp Ala Leu Asp Ile Ser 115 120 125 Leu Val Asp Thr Leu Gln Lys Cys Arg Glu Ala Ser Ser Ser Glu Thr 130 135 140 Ile Ile Ala Ser Thr Tyr His Glu Pro Leu Ser Pro Ala Thr Val Ser 145 150 155 160 Arg Tyr Leu Thr Lys Ala Arg Asn Ala Ser Gly Ile Ser Phe Asp Gly 165 170 175 Asp Pro Pro Thr Phe His Glu Leu Arg Ser Leu Ser Ala Arg Leu Tyr 180 185 190 Arg Asn Gln Ile Gly Tyr Lys Phe Ala Gln Arg Leu Leu Gly His Lys 195 200 205 Ser Asp Ser Met Ala Ala His Tyr Arg Asp Ser Arg Gly Arg Glu Trp 210 215 220 Asp Lys Ile Glu Ile Gly * 225 230 <210> 395 <211> 304 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(47188..48099) <400> 395 Met Leu Ser Pro Ser Ser Ile Asn Leu Gly Cys Ser Trp Asn Ser Leu 1 5 10 15 Thr Arg Asn Leu Thr Ser Pro Asp Asn Arg Val Leu Ser Ser Val Arg 20 25 30 Asp Ala Ala Val His Ser Asp Ser Gly Thr Gln Val Thr Val Gly Asn 35 40 45 Arg Thr Tyr Arg Val Val Val Thr Asp Asn Lys Phe Cys Val Thr Arg 50 55 60 Glu Ser His Ser Gly Cys Phe Thr Asn Leu Leu His Arg Leu Gly Trp 65 70 75 80 Pro Lys Gly Glu Ile Ser Arg Lys Ile Glu Ala Met Leu Asn Thr Ser 85 90 95 Pro Val Ser Thr Thr Ile Glu Arg Gly Ser Val His Ser Asn Arg Pro 100 105 110 Asp Leu Pro Pro Val Asp Tyr Ala Gln Pro Glu Leu Pro Pro Ala Asp 115 120 125 Tyr Thr Gln Ser Glu Leu Pro Arg Val Ser Asn Asn Lys Ser Pro Val 130 135 140 Pro Gly Asn Val Ile Gly Lys Gly Gly Asn Ala Val Val Tyr Glu Asp 145 150 155 160 Met Glu Asp Thr Thr Lys Val Leu Lys Met Phe Thr Ile Ser Gln Ser 165 170 175 His Glu Glu Val Thr Ser Glu Val Arg Cys Phe Asn Gln Tyr Tyr Gly 180 185 190 Ser Gly Ser Ala Glu Lys Ile Tyr Asn Asp Asn Gly Asn Val Ile Gly 195 200 205 Ile Arg Met Asn Lys Ile Asn Gly Glu Ser Leu Leu Asp Ile Pro Ser 210 215 220 Leu Pro Ala Gln Ala Glu Gln Ala Ile Tyr Asp Met Phe Asp Arg Leu 225 230 235 240 Glu Lys Lys Gly Ile Leu Phe Val Asp Thr Thr Glu Thr Asn Val Leu 245 250 255 Tyr Asp Arg Met Arg Asn Glu Phe Asn Pro Ile Asp Ile Ser Ser Tyr 260 265 270 Asn Val Ser Asp Ile Ser Trp Ser Glu His Gln Val Met Gln Ser Tyr 275 280 285 His Gly Gly Lys Leu Asp Leu Ile Ser Val Val Leu Ser Lys Ile * 290 295 300 <210> 396 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48165..48734) <400> 396 Met Leu Pro Thr Ser Gly Ser Ser Ala Asn Leu Tyr Ser Trp Met Tyr 1 5 10 15 Val Ser Gly Arg Gly Asn Pro Ser Thr Pro Glu Ser Val Ser Glu Leu 20 25 30 Asn His Asn His Phe Leu Ser Pro Glu Leu Gln Asp Lys Leu Asp Val 35 40 45 Met Val Ser Ile Tyr Ser Cys Ala Arg Asn Asn Asn Glu Leu Glu Glu 50 55 60 Ile Phe Gln Glu Leu Ser Ala Phe Val Ser Gly Leu Met Asp Lys Arg 65 70 75 80 Asn Ser Val Phe Glu Val Arg Asn Glu Asn Thr Asp Glu Val Val Gly 85 90 95 Ala Leu Arg Ala Gly Met Thr Ile Glu Asp Arg Asp Ser Tyr Ile Arg 100 105 110 Asp Leu Phe Phe Leu His Ser Leu Lys Val Lys Ile Glu Glu Ser Arg 115 120 125 Gln Gly Lys Glu Asp Ser Lys Cys Lys Val Tyr Asn Leu Leu Cys Pro 130 135 140 His His Ser Ser Glu Leu Tyr Gly Asp Leu Arg Ala Met Lys Cys Leu 145 150 155 160 Val Glu Gly Cys Ser Asp Asp Phe Asn Pro Phe Asp Ile Ile Arg Val 165 170 175 Pro Asp Leu Thr Tyr Asn Lys Gly Ser Leu Gln Cys Gly * 180 185 <210> 397 <211> 86 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48781..49038) <400> 397 Leu Ala Thr Phe Phe Ala Tyr Pro Ala Asp Ile Arg Lys Val Ile Tyr 1 5 10 15 Thr Thr Asn Ala Ile Glu Ser Leu Asn Ser Val Ile Arg His Ala Ile 20 25 30 Arg Lys Arg Lys Val Phe Pro Thr Asp Glu Ser Val Lys Lys Val Val 35 40 45 Trp Leu Ala Ile Gln Ala Ala Ser Gln Lys Trp Thr Met Pro Leu Arg 50 55 60 Asp Trp Arg Met Ala Met Ser Arg Phe Ile Ile Glu Phe Gly Asp Arg 65 70 75 80 Leu Asp Gly His Phe * 85 <210> 398 <211> 99 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(49068..49364) <400> 398 Met Arg Leu Ala Glu Asn Glu Gly Ala Asn Phe Trp Phe Asn Val Leu 1 5 10 15 Thr Glu Leu Lys Asn Arg Gly Leu Asn Asp Ile Leu Ile Ala Cys Val 20 25 30 Tyr Gly Leu Lys Glu Phe Pro Glu Ala Arg Ile Gln Leu Cys Ile Val 35 40 45 His Met Val Arg Asn Ser Met Arg Phe Val Ser Trp Lys Glu Tyr Lys 50 55 60 Ala Val Thr Arg Asp Leu Lys Ala Ile Ser Leu Pro Gln Lys Arg Gln 65 70 75 80 Ala Ser Arg His Trp Lys Arg Leu Leu Arg Pro Gly Thr Ala Ala Ile 85 90 95 Arg Arg * <210> 399 <211> 513 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(49700..51238) <400> 399 Met Asn Asp Ile Ser Ser Asp Asp Ile Phe Leu Leu Lys Gln Arg Leu 1 5 10 15 Ala Glu Gln Glu Ala Leu Ile His Ala Leu Gln Glu Lys Leu Ser Asn 20 25 30 Arg Glu Arg Glu Ile Asp His Leu Gln Ala Gln Leu Asp Lys Leu Arg 35 40 45 Arg Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala 50 55 60 Gln Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu 65 70 75 80 Thr Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr 85 90 95 Arg Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg 100 105 110 Leu Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser 115 120 125 Tyr Leu Gly Glu Asp Thr Ala Glu Gln Leu Glu Leu Met Arg Ser Ala 130 135 140 Phe Arg Val Ile Arg Thr Val Arg Glu Lys His Ala Cys Thr Gln Cys 145 150 155 160 Asp Ala Ile Val Gln Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly 165 170 175 Ile Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Ser Lys Tyr Ala 180 185 190 Glu His Thr Pro Leu Tyr Arg Gln Ser Glu Ile Tyr Gly Arg Gln Gly 195 200 205 Val Glu Leu Arg Arg Ser Leu Leu Ser Gly Trp Val Asp Ala Cys Cys 210 215 220 Arg Leu Leu Ser Pro Leu Glu Glu Ala Leu His Gly Tyr Val Met Thr 225 230 235 240 Asp Gly Lys Leu His Ala Asp Asp Thr Pro Val Gln Val Leu Leu Pro 245 250 255 Gly Asn Lys Lys Thr Lys Thr Gly Arg Leu Trp Ala Tyr Val Arg Asp 260 265 270 Asp Arg Asn Ala Gly Ser Ala Leu Ala Pro Ala Val Trp Phe Ala Tyr 275 280 285 Ser Pro Asp Arg Lys Gly Ile His Pro Gln Thr His Leu Ala Cys Phe 290 295 300 Ser Gly Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr 305 310 315 320 Arg Asn Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg 325 330 335 Lys Ile His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu 340 345 350 Ala Leu Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg 355 360 365 Gly Met Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys 370 375 380 Pro Leu Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr 385 390 395 400 Leu Ser Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn 405 410 415 Gln Trp Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile 420 425 430 Asp Asn Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg 435 440 445 Lys Asn Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala 450 455 460 Leu Leu Tyr Ser Leu Ile Gly Thr Cys Lys Leu Asn Asp Val Asp Pro 465 470 475 480 Glu Ser Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val 485 490 495 Asn Arg Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu 500 505 510 * <210> 400 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(51288..51635) <400> 400 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Asp Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 401 <211> 127 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(51632..52012) <400> 401 Met Gln Lys Asn Val Thr Pro Gly Arg Arg Lys Gly Cys Pro Asn Tyr 1 5 10 15 Pro Pro Glu Phe Lys Gln Gln Leu Val Ala Ala Ser Cys Glu Pro Gly 20 25 30 Ile Ser Ile Ser Lys Leu Ala Leu Glu Asn Gly Ile Asn Ala Asn Leu 35 40 45 Leu Phe Lys Trp Arg Gln Gln Trp Arg Glu Gly Lys Leu Leu Leu Pro 50 55 60 Ser Ser Glu Ser Pro Gln Leu Leu Pro Val Thr Leu Asp Ala Ala Ala 65 70 75 80 Glu Gln Pro Glu Ser Leu Ala Glu Asp Pro Glu Thr Leu Ser Ile Ser 85 90 95 Cys Glu Val Thr Phe Arg His Gly Thr Leu Arg Phe Asn Gly Asn Val 100 105 110 Ser Glu Lys Leu Leu Thr Leu Leu Ile Gln Glu Leu Lys Arg * 115 120 125 <210> 402 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(52352..52630) <400> 402 Met Pro Phe Ser Ile Lys Ser Ile Phe Ser Gly His Thr Trp His Gln 1 5 10 15 Pro Glu Ile Ser Arg Pro Ile Ala Asp Lys Ser Ser Thr Lys Asn Cys 20 25 30 Ile Leu Asp Ser Thr Thr Cys Asn Val Asp Gly Phe Thr Val Phe Asn 35 40 45 Arg Arg Ser Cys Ser Phe Asp Met Arg Pro Pro Gly Ser Ala Asp Arg 50 55 60 Thr Pro Gln Leu Arg Leu Ser Ile Ser Glu Val Ala Trp Met Ser Lys 65 70 75 80 Ile Ile Glu Thr Glu Thr Asn Asn Thr Asn Lys Ser * 85 90 <210> 403 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(52844..52996) <400> 403 Leu Arg Asn Ile Gly Gly Glu Arg Ile Ile Phe Ser Ser Trp Tyr Ala 1 5 10 15 Phe His Ser Glu Thr Gly Lys Val Gln Gln Gln Glu Leu Lys Leu Arg 20 25 30 Gly Ile Tyr Gln Ser Ile Tyr Ser Pro Trp Met Asn His Ala Val Arg 35 40 45 Leu Trp * 50 <210> 404 <211> 49 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(53058..53204) <400> 404 Leu Ile Phe Ile Ala Ser Ser Ser Arg Glu Gln Thr Thr Ala Ser Asp 1 5 10 15 Gly Lys Met Gly Thr Thr Gly Tyr Ser Gly Asn Leu Ala Glu Glu Ala 20 25 30 Tyr Gly Thr Asp Cys Asn Val Lys Tyr Lys Thr Leu Lys Ile Pro Phe 35 40 45 * <210> 405 <211> 216 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(53341..53988) <400> 405 Met Pro Val Ile Leu Asn Phe Ser Ser Glu Arg Val Leu Ser Glu Ser 1 5 10 15 Glu Leu Glu Ala Leu Arg His Val Gly Arg Val Ser Gln Ser Glu Gln 20 25 30 Leu Val Val Arg Gly Arg Thr Met Arg Leu His His Ile Ser Phe Met 35 40 45 Asp Ser Phe Ser Val Glu Pro Val Ser Gly Gly Leu Leu Asp Arg Leu 50 55 60 Ser Ala Arg Gly His Arg Leu Leu Ala Glu Asn Leu Glu Ile Gln Leu 65 70 75 80 Asn Arg Gly His Thr Phe Leu Gln Ala Phe Arg Leu Tyr Met Glu Gln 85 90 95 Ser Arg Ala Thr Pro Cys Thr Arg Gln Asn Val Ser Ser Ala Ile Gln 100 105 110 Asn Lys Ile Asn Ser His Ala Phe Thr Val Ser His Gln Asp Phe Ser 115 120 125 Cys His Glu Gln His Leu Asn Cys Pro Ile Thr Leu Cys Ile Pro Glu 130 135 140 Thr Gly Val Phe Val Arg Asn Ala Lys Asn Ser Glu Ile Cys Ser Leu 145 150 155 160 Tyr Asp His Asn Ala Leu Thr Glu Leu Ile Arg Arg Asn Ala Pro His 165 170 175 Pro Leu Ser Arg Glu Pro Phe Val Pro Glu Met Ile Val Ser Lys Asp 180 185 190 Glu Cys His Phe Asn Leu Ile Glu Gln Tyr Phe Cys Ile Leu Ala Thr 195 200 205 Gln Asn Ile Cys Thr Arg Ile * 210 215 <210> 406 <211> 197 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(54172..54762) <400> 406 Met Pro Val Asn Ala Thr Gly Val Ser Phe Ser Ser Phe Gly Ile Ser 1 5 10 15 Tyr His Lys Asp Asn Ser Phe Arg Gly Thr Ile Arg Gly Lys Asn Asp 20 25 30 Glu Val Val Lys Cys Ser Met Gly Glu Arg Ser Ile Arg Phe Asn Val 35 40 45 Asn Lys Phe Ser Gly Cys Ile Leu Glu Thr Val Ser Arg Gln Ser Thr 50 55 60 Lys Asp Ile His Gly Trp Val Ser Asp Glu Arg Thr Val Tyr Pro Ser 65 70 75 80 Arg Val Ile Asn Gln Glu Ile Asp Asn Cys Cys Leu Gln Lys Asn Ala 85 90 95 Lys Ile Ser Ser Glu Glu Arg Lys Met Val Phe Ser Leu Val Ser Lys 100 105 110 Glu Phe Glu Leu Thr Leu Asp Val Lys Ala Ala Gln Ser Ser Ile Asn 115 120 125 His Ile Ile Ile Gly Asn Ala Ser Phe Gly Lys Lys Met Asp Ala Leu 130 135 140 Cys Asp Gly Met Ser Arg Ala Val Lys Asn Ser Thr Thr Asp Tyr Ile 145 150 155 160 Ala Asn Val Leu Ala Asp Lys Phe Tyr Gln Lys His Ile Ala Pro Gly 165 170 175 Val Asp Ile Val Lys Leu Arg Asn Glu Ile Pro Gly Tyr Met Ser Arg 180 185 190 Val Ile Gln Gly * 195 <210> 407 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(55196..55378) <400> 407 Val Gly Ala Asn Ser Lys Ser Ser Ala Leu Phe Ile Arg Leu Leu Lys 1 5 10 15 Arg Leu Lys Ala Thr Tyr Cys Arg Thr Lys Thr Ile Thr Leu Leu Glu 20 25 30 Asp Asn Tyr Ile Ile His Lys Gly Arg Glu Thr Gln Arg Trp Leu Lys 35 40 45 Asp Lys Pro Lys Cys Arg Val Ile Tyr Gln Pro Val * 50 55 60 <210> 408 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(55873..56037) <400> 408 Met Ser Ile Ile Pro Pro Ile Ser Arg Asp Glu Arg Arg Leu Ile Gln 1 5 10 15 Lys Ala Ile His Lys Arg Leu Thr Ala Met Leu Met Leu His Arg Gly 20 25 30 Asp Arg Val Ser Asp Val Ala Arg Thr Leu Cys Cys Ala Arg Ser Ser 35 40 45 Val Gly Arg Trp Ile Asn * 50 <210> 409 <211> 170 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(56410..56919) <400> 409 Met Asp Ala Phe Ile Val Asp Pro Val Gln Gly Glu Leu Tyr Ser Gly 1 5 10 15 Leu Ser His Thr Glu Leu Ala Asp Ile Ile Arg Leu Ala Asp Ser Val 20 25 30 Glu Asn Gln Leu Asn Gly Gly Asn Ser Phe Leu Asp Val Phe Ser Thr 35 40 45 Tyr Met Gly Gln Val Ile Ser Glu Phe Met His Ser Asn Asp Asn Arg 50 55 60 Ile Glu Leu Leu Gln Arg Arg Leu His Ser Cys Ser Phe Leu Val Asn 65 70 75 80 Ile Glu Glu Met Ser Tyr Ile Asp Glu Ala Leu Gln Cys Pro Ile Thr 85 90 95 Leu Ala Ile Pro Gln Arg Gly Val Phe Leu Arg Asn Ala Glu Gly Ser 100 105 110 Arg Val Cys Ser Leu Tyr Asp Glu Met Ala Leu Ser Arg Ile Ile Asn 115 120 125 Asp Gly Met His His Pro Leu Ser Arg Glu Pro Ile Thr Leu Ser Met 130 135 140 Leu Val Ala Arg Glu Gln Cys Glu Phe Asp Cys Ser Ile Gly His Phe 145 150 155 160 Thr Val Arg Ser Asp Cys Tyr Ser Val * 165 <210> 410 <211> 49650 <212> DNA <213> Escherichia coli O157:H7 <400> 410 ttatctggcg gaagcgcaga gattcgaact ctggaaccct ttcgggtcgc cggttttcaa 60 gaccgaagaa aaacaaataa aaatcagtgt aatacgtgaa attgctgaaa agttaatcaa 120 atttaacacc aagaaaaatc aaggtattag gaagttgctc atagctagta taccaagtct 180 ttttgccaga aatttttctg gattgtctac ttgctaacca cgagcggcaa atccagtgtt 240 ggtgtgattt ttgttttacg atcgtaaatc aacacctgat tttctgtttt atgcccgctg 300 aaaatttgtt tgtcgcgact gctgccttcg taatctgaga tccccttggc ttttatgtcg 360 tgaaaattgc acccgaacgg aacgccaact ttttgctcgg ctgcgcgttt agcctgattc 420 caccagttat tcagcgtttt agctatgact ttcccgcctt tggttgtatt gatcacatat 480 tcgcatgtac aggaagatac atttcgggct aactggatcg ctgtacgtaa tcgcggtgac 540 cattccttga tttgtttggt gccggttttg ttttgctcaa tgtagatccc tttatccata 600 atatcctgcc atttcaactc aagcacatca ccgagtcttg ccgcacagag ataggaaatc 660 tccattgcaa tgcgtaactg tggaattgct tccgcatata tcgccgcata ctgttcatcg 720 gtgatgtaaa cagtgcgggc tttaagagag aattttctga ctcctttgca tgggttattc 780 ttcacatacc cacgctcata tccccacccg tatactcgac tcaggcttgc cagttcatga 840 tttgcctggg tcttgctctc aagccctcgt ttatccatga aaattcttac ctgctcagtt 900 ttgacattat cagcaagcac ttttccgaat accatcagca acgccttctg atgttgtcga 960 taatcttttt gggttcgggg ggccagttct gtaaatgcag gggagtccat aaacatgtgc 1020 cacaatttag ctacggtcat tatgttgtgg agttttgctt tttccagttc ataattttgc 1080 cagactttag ctacgctggt tttccgcact cttcctagcc ctatacttct tgtacttcct 1140 tcgggtttcc acacgtaact gtaaccattc gatctaaccc gcggtggcag tacattatct 1200 tttttatttt ttcttggtct tcccattgtt cagcgcctca aaatcgggtt cagcagaaac 1260 cagttcagat gtttttggca tcgttgtcag accgtgtgga atatccctgc ggagaactat 1320 gggttcgttt ttagggccga ttacaaatgg gatgccgtgc agtcttaact ggtgttgctg 1380 ttttgtgtat cgctcgtatt tcgtgatctc tttaatctct gctggagata gagttaattc 1440 gtacatgtgg tcacgtgcct ttacagcatg accgcggcca ctatagctgg tgggcggcga 1500 tatgggttga acatcaaaaa tcagcctgac tcgggagcag tttttgccag atggctgaaa 1560 cgtatttcgc ctggtaacgt gcatcgtgca gggcgttatg gcgttcacct tcgaatggaa 1620 tagtcgttct tgcgtcgaaa tccatcacca gtcccagagc aaccatcgtt cttacatcgc 1680 gatcattggt gtaacgccac gggcagggga tcccctgccg ttcatatgaa cggcgtaaaa 1740 tcacgttgtc gaaagttgca ccgttacccc agacctgaac aaaaaattca ccggagtttt 1800 cgtcgataaa ttcccggaat tgcagcagtg catcatccaa cgtgatttca tcggtcagaa 1860 tggaggattg tgcttcgcgt gactgtttca gccaccactt aatggtgtcc cgatcgatga 1920 ccccacctgc ggtttccaga tcgatagttt tgctgaattc tggccccatc tctccggttg 1980 ccggatcaaa aaacttaccg gctatagagt ttattggcgc atcaggattt tttcccattg 2040 tttcaaggtc aatcatcaga tggtgccaca acctgctggt ggatgagatt tcatgatgac 2100 cgttcacttt aattaaggga tttgctgttt cgccagtttt attatcgctg gcgtgatact 2160 gatcgctgcc agtgttctcc ttgtgcagat gttcagtgcc ttccatttcc tccggatcat 2220 ttttctgagc ttcagcctga ttctcttcat cgaatgtttc caggtaggtt gcgttcccca 2280 tcaccgcacc acagtcagga cagttgccgc caccggtctg accgcatgcg gtgcaaactt 2340 tttccagttc ctgttgcact gctggttctg gttgttgttc ttctggcccg ttttgttgcg 2400 tatccgggct gttttgttcc gcttctggct cattttgttt cacgttgggc tgattctggt 2460 cctcagcgtc gcgactctgg atccctttca cccatttcgg atcattcggg tcgctaatcc 2520 cttcaacaaa ttcaccacgt gatgcagcaa gcaatttatc ggcgtcaggc tggctgatat 2580 tggctgcctg cataattttg tttacttcgt cagcggtaac ttttaccggc tctgattgtt 2640 cggaatcttc agcggtatcc acattttgcg gtaagcccgt gtatgtgcca ttttttcggg 2700 caaaatattc ttcttttgag atttcggtac cgccggcagc cagcgccttg tccagaccag 2760 aaagtttgtt tgccctgccg tatttttccc cgcccttatc ggtaaagacg aaataaaatg 2820 gtccttcacg ctctacagat ggttcagctt ccaccaggat ttcatttttt tgagtatcgg 2880 attctgccgt ctccactgga gcagtttgtg ctgctgacgg ctggagagca tcagtagagc 2940 tctggtctgt ttcttcatgt tcaaacacgc cctttgtcgt caggtattca ctgatatatt 3000 tgttcagtgc aacgggatct ttgtgaatat cgatcggacg ttcgcgaaca aggccaaaaa 3060 tagtctgacg gtcatagcca agtgcttcgg gctgtttgcg cattgatgct gagatacgct 3120 tccagtcttc gcgatccttg tcgataacct catttgtcgc ccagcgatgg atggtaccgt 3180 caatgtttcc tgcatccaca tcaccgggcc agagggcgca ggccagttca ttgtcgagtg 3240 ttttccatgt ctgtttgtat tcgcggcgaa tggcaacagt gacagccccg gttttttcag 3300 cagcgttttc agtgttctgt tggttgactc tggcgcgggt gagatcaaca acagacgtgt 3360 attttccggt ttccttgcgt tcaccttcgc gacgtttttt ccagatgcgc atctctgcct 3420 gaatttcagg ccatttagcg ccaggctcac atttatgctt aacccacccg atggcatgca 3480 gtttaagttc aggatacatg gcgttaactt ctggcatttt catcaacgct tcaacgatat 3540 gtccgccgaa tgttgccatg tcttcctgta gtaattcctg tgcgctaatc accatatcaa 3600 cggtgatgtt ttcgcatgtg tcgaatttaa ccaggactgc gttctgtact tcaggggaca 3660 gcttgtcaaa attgacgttc atcggatcgg attctggttc gaccggtaca aaggaagctg 3720 actcctcatc ccagcggttt tcctgcatat attcggtatc ccaggaatcg agggcagggc 3780 ggggtatgcc gggtttatcc tcgcagacaa taaatttata agcgcagtcc tgagctgccg 3840 ggaattgctc cagaaattgc cagtgaaatt ttgcgcgtgc gcgacgctca tcaccggctt 3900 caatggcagt ggccaccgca acagcgctat cttcttttat ggcctgttcg tcaggaatag 3960 cagcgcaaat aaagatttta ctcattgtgt tttaacctca ttacagattt aagggtgaac 4020 aaatccctgc cattgctggc atataaaaat gaaaccggat attaattacg gtgctgtttt 4080 aaagtcctgc cggtatttcg ttattattag tgtgagtagt tttatctacc ggataacagt 4140 taccgggaat tttttgttct gctgctgcag ccatgcattc tttcattgaa ccgtataagc 4200 cagtcaccag ctcaagagat tcgccggaaa caagataaac tgtcagaacg agtgcaaatg 4260 ttgtattcat tgtttatatc ctttttgcag caggtccaga cgagccagca ttgaaggaat 4320 gcatacttca tttaacaggt cctgctcgag ttttctctgc ttaatggcgt cttcaataaa 4380 tgttttgtct ccagtgataa cgccaatttc gaaacgaagt tcagacgtgc tggcattaca 4440 tgataacttt tccattatcg cgtcctcaac aatgaatttt gtgatgcggt gcctggtgcc 4500 tccaggtgac gttaaccagt taacaattaa cgccggatac agagcattct cgttactcag 4560 caaatgaccg ctttaccgat ttaactgttc cgcgtgcgct gagccgcatt caccgcatca 4620 caaaattcac ttttaaaaaa gggcggcaga gcagttacgg agtaaaactg ataccgccaa 4680 atgtcaccag aatattgata acagagggcg ttgcagcggg gttgtcactt aagcgtatgg 4740 tcaacctgac aacccggtgt cctcaacggg gaaagaataa ccccgccata cttaccgccg 4800 cgccatttcg cggattgcca caaccggaag cgcacggtcg aattaaattt aacgacggct 4860 ctaagggaga aggacttcgc cgtgcacttt cgtgttatgc cctgactttt cagggatata 4920 tcctttcagt aaactgtcag tgccggattc ttatctgtgt ccggcgcacg accacacgta 4980 gcagcgtgtt ggtctccatt tttaattcag cccttaatgg aggataaaat gccaaacaaa 5040 ccatgccctg cctgtaacgc tctttctggc tttttagaga agggcggtta ttacattttt 5100 aactgtccag aacatgttga atttcatata tcaaaacttg acagtatcat tacaaagcca 5160 aatcagtatc agtctgattt actgaataaa gagttaaacg ccgcccgaga ttaagggcgt 5220 agtggcccat taaaaatatt gcaaagacca actattgttg aactggatta aaccagtaat 5280 tctctattgc tcttattgtt accatcggat gattgccggg ggttatttta agttcgggag 5340 gaaaaggctc tccatcagca gccatcattg agtatgtgaa atccgccgac gcagtccctt 5400 tcatgataat tccgaatttt tcaagtaatg agagcagttc cggtaatcct gtgtcatctg 5460 aataactttc ctcatagaaa gaagcgattg ccgcaggaga tgacagttct cgctctgcaa 5520 tttttttgta gttttccaga attctttttt tgaatacttt tcctcgacat gaaaacccat 5580 caccgaggca atccgctttg cagtttcttc agtattctgg ttgtttgtta ccgaaacaga 5640 gtacaatccg gtaaacgcat cgcgcacatt acgagccata ttatcaatgt atttcttcgt 5700 tgcagattct aattcaactt cgttcagacg ttggtgaagt gcatgtgctg caatttcctg 5760 gatttctttt agtaaatctt taaattccat ctttaactcc gttagtcgtt agattttgcc 5820 gaactggaaa gcgcctgttt aaactcactg aagctgagag cttcctcgcc ttcggcaagg 5880 ccttcgaagt attcttcgta agccttttcc atgattgtgt cgaaatccat atcactcacc 5940 tgagtttctt tccagccagc gacgggcacc attttcggtt ttaaacgttt tgcttttggt 6000 atacgtcatc gcggtgaatg taccgtcctg gttgggaaac acgccgtaca ccagagattc 6060 gttgttgcca agatcgatag tatccatgtt gacctcattt ccccttaacg ccgggtagcg 6120 gaacaaaaac ctgctgcata gttattaaag ttgaaccctg ccgtcatgtt catacgcctc 6180 gggctggcta cttaccccct gaccactgct tggtaactcg aagtattgcc cggcgttctg 6240 tggggcgggg tgggtggttg gtgtatgtaa tctacaataa aaaactgttt ttgtgtcaac 6300 agtttttaat tgttgttttg ggcaaaaaaa tccctcgaaa gagggagtat gaaaattgtt 6360 caactcagat agagaaggga aattgtcgcc gagaatgtgt cacgcttaca atctcaatgc 6420 ttgaagcagc tactctgtac aggattatgt agttagggtg ggtcacgatc tctctcaatc 6480 cagaaacccg ttcgcttggt ggatataagt acggatgctc agatagaggt aataccgatg 6540 tttcaatgcg tatttttagt ctacgtgctg ccggtgggtt ctccttggcg atgtaagtta 6600 tgatctggcg caaatcatcg cgagcagacg gtagccataa aatgggtaac attactcgct 6660 cttgttagtt acagcaattt gagcaataag attttccatt tcagccatta cctcgtcatg 6720 tggaattgcg gggcgagtgt ctgcaaggct tgacgttact ttagtgcgca accattcgtt 6780 gtaactgttt tcttgttcgg tagtttcgaa ttctgaaact atcggagaaa gggctgtacc 6840 catggcataa ctcctcttct tgtactgtgg tcacgcccgg cggctttttt gtgccgccag 6900 ccacctagca atggtttctt ccattgattt tttcttgtct ttgatttctt gaagcatttt 6960 ttcttggtct tcctcaggaa acgcactaaa agcttggagc agttcgcgtt ggcgaggacc 7020 aattttcatc gtgtcagggg tgaaaatttg ctcacactct tcaggaggca ataaaaacca 7080 atgcaatgga tgccctgaaa cctcaaccag tttatccaaa cttgaggctt taggtgtagc 7140 cttaccgctg acccattgtt gaacagtttg ttgtgtcaca ccaattctac gggcaagctc 7200 agcctggctc catccagttt cctgaagaag cttgctgatt ctgtacatag atacttctag 7260 ggcgctcatc attattcaat tttacaggta aatactgtta aaagcatcac aataaaaaac 7320 tgttgattgc atacagtttt ttattgtagg ctttgcttat agtttttaga ggagggcaaa 7380 atgctagata gcactcgcga aaaaattagg cagaaataca ctcaggctga aataggtcgt 7440 tatatggggg tcgctcaaca gactgtttgg caatggttta gctttggcgt tcccccaaag 7500 caggtaattc cgttatgcca actaatgaag tgggaagtta ccccgcatga aatccgccca 7560 gatatttatc ctaacccaac cgacggttta cctgttggat gtaaggttaa cacatcaaat 7620 gcgccggagt tgattcatga aaatcaagca tgaacacatc cgcatggcga tgaatgcctg 7680 ggcgcatccg gacggcgaaa aagtaccggc tgcgaaaatt accaaagcgt atttcgagct 7740 gggaatgacg ttcccggaac tgtatgacga cagccatccg gaagccatgg ctcgcaatac 7800 tcagaaaatt ttccgctggg tggagaaaga cactcctgat gcggttaaaa aaattcaggc 7860 gttgttacca gcgatcgaaa aagcgatgcc gcctccgctg gtggcccgaa tgcgcagcca 7920 cagttccgct tattttcggg agttggtaga gacgaaggaa cggctggtga aagatattga 7980 tgatttcgtt gcatcagcga tcgttctgtt cgatcagatg aatcgtggtg gcccggcagg 8040 aaacactctg gctgtgcatt aattgggtaa taaatatgag taatgacaaa aaattgacac 8100 tgagcgttta cgaaaacagt ccgcacatct ggcgtggcgg tttatctgat gtggagctgg 8160 cagagtggtt gatacataaa gctaatgcgc tgctctggcg tttgtcagcc agagaacagc 8220 gcaaggaaac cagaataaag ctggctgatg cagaagcgtg tgccgggctt attgaggatt 8280 atacaaatct tggtatttct tcagcagaga gtgatcccat tcagcctctg agcagggagt 8340 caatccagca cgctggttgt atggcacatc ttgtaactgc tcgtcaacat gaggtgggta 8400 ttggatcact tccggcggga tattcgctga ttccagagct ggttgaagca agaaaatcag 8460 ttcagaaaaa gagagatgac gcacttcaat tattgagaga gcactatggc gcgataccag 8520 aatgcgaaca gcgtcgatac cctgaaggtt atgaatggat gcagtctctt tttgaagttc 8580 gctaatcaat atgtcgagac gaaggtatgt ttcggcgcgc agccaggctc tgtaatccgg 8640 gagcatttcg gggctgttac accagcggtt tgttgctgca acatttaata catgagcctg 8700 ataaaggctt ttcaaaaaat acatgtcgaa cctcctctgg ttctgtcgat tgggaaccac 8760 agattatatc cggaggaagg ttcggcacca gatgaggtag ccatgcgtga ttacgcaaaa 8820 gtttctccgc gattctggct gggagaaacg gggagagaac ttagaaaggc gggtgcagaa 8880 gcgcaagttg ttgcttttta cctgatgaca tcccctcacg caaatatgct gggtttgtat 8940 tacctgccag ttttatacct tgctcatgaa accgggcttg gtctggaagg ggcttcaaag 9000 gggcttaaaa gggctgttga agctggtttt tgtagctatg accatgatgc agagatggtc 9060 tgggtccatg aaatggcagc ctggcaggtt ggggaaacgt tgaagcctgg cgataaccgt 9120 tgtgcaggtg tcaggaatga gtatgcatca ttacctgaaa acgcttttct gtcagtgttt 9180 tacgacagat ataaaacgga tttccatctg gatgtgaggc ggaataatag ccgaaattcg 9240 gtaaggggct tcgaaggggc ttttaagggg cttcgaagcc aagaacagga acaggagcag 9300 gagaaagaac aggaacagga caaaaacact atggttcatg gcaaaaaaaa caccacgaac 9360 caggcagggg atgttcagac cgtcaatcct ggtcagccag caggcacgac accggaagcc 9420 gattcgggcg ctgtgcagca ggtgatgacc gcagggtcgg agcaatcaca ccaactgcag 9480 cagcctgaag ccgattccgc cattcagcgg gaagccgatc gggtagtccc ggaaagcacc 9540 gggcagtctg tgggacgagt ggattatccg gatgtgttcg aacaggtctg gcgggaatac 9600 ccgttgcgtg ctggggcaaa cccgaagaaa tccgctttca gtgcctggaa ggccagattg 9660 cgcgaggggg tgccaccaga gaccatgctg gatggtgtga ggcgttacgc gagatacctg 9720 gcggcgaccg ggaaagcggg aacggaattt gttcagcgag cgacgacgtt ttttgggccg 9780 gaccggaatt ttgaaaaccc ctggttgctc ccggtaagcg gcacgaacaa ccagcgttgt 9840 gtgaatcata tttctgaacc ggataccgaa attccgccgg gattcagggg gtgatgtggc 9900 atgaaaaaca ttgcggcagc cggggttctt gaacgtattc gcagacttgc accacaggcg 9960 tcggttccac cgtaccggac ggtggaggag tggcgggaat ggcaacttgc tgaaggacga 1002 0 aaacgcagcg aggagattaa ccgccagaat caccagttgc gggtggaaaa aatcctgaat 1008 0 cgttcgggca tccagcctct gcacagcaaa tgctcgtttg cgaattatca ggtgcagaac 1014 0 gacgggcaaa aatacgcgct gagccaggcc aaatccatag ctgacgaact gatgaccggg 1020 0 tgcacgaatt ttgtgttcag cggtaaaacc ggcaccggga aaaatcacct tgcagcggcg 1026 0 atgggtaacc ggctgatggc gaaggggcgc agcgtgatta tcgtcaccgt gtctgatgtc 1032 0 atgagcgtgt tgcatgacag ctacgacaac ggcaaatccg gggaaaaatt tttacaggag 1038 0 ctttgcagtg ttgatttgct ggtcctggat gaaataggcg ttcagcggga gacgaaaaac 1044 0 gagcaggtgg tattacacca gataattgat cgccggacag catcactgtg cagtgtcggg 1050 0 atgttaacaa acctgaatca tgccgcaatg agtacacttc ttggtgagag gattatggac 1056 0 cgcatgacca tgaacggtgg tcgatgggtg acgtttaact gggatagctg gcgtccaaat 1062 0 gtcagcaata tgagggttgt gaagtaattt tgtccggagg aaattttaat ggaaaccgta 1068 0 tctgacgcac tgaaagcact gaaaaaagcc tcttcacatg tggtggcagc tcgccttgga 1074 0 atcagtcgtg aagaggctgt caacgagctg tgggaactca aaataaatgg cgtcgttgat 1080 0 aaaactggtc acacctggtt tctggctggc gaaggtgaat cccgggtaac cgaagagcgg 1086 0 ccagtaaaat ctgaagcaca ggatatgctg accggggagg tcgaacaaaa agttaccgca 1092 0 gacatgatga ttgagtttat cggtcaggat ggggctaaaa cgtgtgagga actggcgggt 1098 0 aagttcggtg tcagtactcg caaggttgct tccacgctgg cggtggtaac cgcaacgggg 1104 0 cggctggcac gcgttaatca gaacggtaaa tttcgttact gcatgccggg cgataattta 1110 0 ccagcagagc cgaaagccgc gctggtaacg gaaagtgatg gtaaggcctt tcctcagcca 1116 0 gcaggtgctg cgttaccagt ccgggaagcc gcaacacagg aagaaattaa aacagaaact 1122 0 gtggcggaca ttgtgcagcc gttgccatcg tttaccgaaa cgcaagcaga tgagctgatt 1128 0 tttccgtccc ttcgcagggc aaacctggcg ctgcgcaggg cgaaaagtga tgttcagaag 1134 0 tgggagcgag tctgcgccgc gctgcgggag ctgaacaagc accgggatat tgttcgacag 1140 0 attactgatt cttcccgccg tgttgtatcg gaaaagtgat tgccggaggc gcttatggca 1146 0 aaagtattta cacaggaaga gcgggaaaaa attaaagggc aggttgttga gctagtacgc 1152 0 cggagtgggc gcgagacgtt acggcaactg gaagccaaga caggtgcgac aagatatctg 1158 0 atgagcgttc ttgccagaga gctggttgcc agtggcgatg tatacaactc tggttacggg 1164 0 ttattcccat ctgaacaggc tcgtaaggac tggcaaaacg cccgcaaaaa actatcgagg 1170 0 gcaaaactga agaaaccggt tgtggttgat cctgacctta tctggtcatt accagacgga 1176 0 gaaatacgcc gctatgacag gcaattgaac ataatttgta gtgagtgccg taacagtgaa 1182 0 gtgatgcagc gagttttgat attttacaca ggagtaatga tggaatagtg aaaataacat 1188 0 gaaacctttg gattctggtg tttcagtgga tgggaaaaga gcagatacat agaaaatgaa 1194 0 tagcaataat tcacagtctg gatgttgttt gtatgcttat aaaatgatcc tagtatgcat 1200 0 tgccggagtt gaatcagctc caatgaagaa actgagagga gtatttagaa gatagctaaa 1206 0 tggatgtaat tattagtatc taaaaaatag tatttttgaa atgggtctaa gaacacaaca 1212 0 atgtacaaat gagaagttat cttttaatat gttcaaagac ccattaggat tgatatcagt 1218 0 tatgttagct agattgataa agtgattaca tattttctgt tatatgctga aatgaataat 1224 0 gctattccag agtgcagcag agaaagtctc ctgatgattg agctctggaa attgtacaat 1230 0 agaaaaatta ctgtattttt ctgtcaaaat atttctcaaa acagattccg ctttgatggc 1236 0 ttcaggatat aaagatgcgg agtaatcaag gctaagattt ccgttaagca agcatatact 1242 0 tttagtgtgc tttgattctg atatatcatc tttaattatc ttgatgattc tttcattctg 1248 0 ccatagaagt gatggtgcag atatataata atagttaaag catgaattat tttttaagca 1254 0 atcaagcaca aaaatagcac ctagcgagtg tccccatata ccgattctgg aactgttcgg 1260 0 agcaatagta ctaacccatg gcatgatctg agttagtaat aattctcgga aagactggct 1266 0 tcctccacca gtaaagtaga tccatgctgg tttagagtta tcaacaatag cattttcacc 1272 0 atcaggagta taatcgtaag cacggcgatg aatgctaagg ttattccaag attcataacc 1278 0 aagtgtaact aacactggtg gattgggtag tgcatcaata acaggcagaa tatcagaaat 1284 0 gtaattgttg gcactattcc catcaagtat ataaagagtt gcattatttt ttttaatgtt 1290 0 ttttggagta aaaatacata ttttatattt ggtgtcatgg ttaattgagt taaatatgcg 1296 0 tgtttgacaa tgaatgtcca tatgtttagt catgcgttct ccccatgagc attaaaggat 1302 0 gcttaagata tgctatgtca ctgataaaaa atttgttgtg tgtgtttagt tattttatct 1308 0 acctccatta tgatttaaga ctgatatatg ttatcagcaa aggtacatcg ttattatttt 1314 0 acctgtcaat acatttgata ttgattatcg tttacatcgc ttgcttagga aattgaaggc 1320 0 aggtaactat catgtcaatg aactaaccca cagtctaacg tacttctttc cccaatcacc 1326 0 aacaaccaaa ttcctgttat caccactggg attttggcgc aacttcatgg tgcagaggta 1332 0 aatagcatca agcaaaatct ctttttccgt tgttgtcctt atgggacgtc tgtctttctg 1338 0 accgatttca tattggcgag gtaatgggaa gttaagtaga atagctgcgg gtgcttgagg 1344 0 ctatctgcct cgggcatgaa caccaacggc agatagagaa aagccccagt taacattacg 1350 0 cgtcctgcaa gacgcctaac attaatctga ggctcaatct atgaacggca aatctaggtt 1356 0 agcctcttac gtgccgaaag gcaaggagaa gcaggctatg aagcagcaaa aggcgatgtt 1362 0 aatcgccctg atcgtcatct gtttaaccgt catagtgacg gcactggtaa cgaggaaaga 1368 0 cctctgcgag gtacgagtcc gaaccggcca gacggaggtc gctgtcttca cagcttacga 1374 0 acctgaggag taagagacct ggcgggggag aaatccctcg ccacctctga tgaatcaggc 1380 0 atcctcaacg cacccgcact taacccgctt cggcgggttt tgttttttcc tggcattctg 1386 0 gtttacaatt cgcacgccag cctgaacaac tggcacctgc tgcgccagca gagacaaccg 1392 0 atggcgcacg ataccaaatt atacaattct gatgattctg ccgtctttgc cagcaggcgc 1398 0 ggacggtgtt ttcacgcatt caaatctgac tggtaccagc atcccccatg cactgaagaa 1404 0 caggccgaat ggctcattca gtgttaccgc aggcgcggat gcgaggttaa aaaagccctt 1410 0 agcctcgact accgtcactg gataatctcc gtcaggctcc cttactccga acggccaccg 1416 0 cgtccgtccc gcacattcca gcaacggatc tggaggtaat gtgcgggtat tacttcgacc 1422 0 tgttctggta ccggaactcg gtctggttat cgttaagcca ggccgtgaat caatgtcagc 1428 0 attccataac ggcagaatac tggtggagcc ggaaccaaaa agcatgcgag ctctgccgtc 1434 0 cggggttgta cctgccgttc accagccgct ggcggaagat aaatcactac tgccattttt 1440 0 cagcgatgag cgggtgatcc gtgctgcggg tggcgctggt gcactgtctg actggttatt 1446 0 acgtcacgtg aaatcctgcc agtggcctca tggtgattat catcacagcg aaactgtcat 1452 0 acatcgttac ggtaccggcg cgatggtgtt gtgctggcac tgcgacaacc agctgcgcga 1458 0 ccagacatcc gaatcacttg agcaacttgc tcaacagaat ctggccgcct ggatgattga 1464 0 cgtcatccgc cacgcaatga atggcataca ggaacgggaa ttatcgctgg ctgaattatc 1470 0 ctggtgggca gtctgcaatc aggtggtgga cgcattacct gaggcagtat cgcgtcgttc 1476 0 tctgggatta ccggcggaaa aaatccgctc cgtataccgt gaaagcgaca tcataccggg 1482 0 agaacagacc gccaccagca tactgaagca gcgcacaaaa aatattgcgc taccgcctca 1488 0 cacccaccag caacagaacc caccacagga aaagacggtg gtcagcattg ccgttgatcc 1494 0 ggagtctccg aaatccttca tgaaacgacc taaacgtcgc cgctgggtaa atgagaaata 1500 0 cacacgctgg gtaaagacac agccgtgtgc gtgttgtggt aagccagcgg acgatcctca 1506 0 tcatctgatt ggtcatggtc agggtggaat gggaacaaaa tcccacgata ttttcacgct 1512 0 accgctgtgt cgggagcatc acaacgagct tcatgcggat ccgctggcgt tcgaagaaaa 1518 0 gcatggttcc caggttgatt taatttttcg ttttcttgat cacgcttttg caaccggcgt 1524 0 gctcgggtaa aagaggttac tgatgcgtat agagtttgtt ttgccttacc cgccgacggt 1530 0 gaacacctac tggcgacgtc gtggcagcac atattttgta tcaaaagccg gtgagcgtta 1536 0 tcgccgggct gtggcgctta ttgttcgcca gcagcggctg aaattaagcc tgtccggacg 1542 0 gctggcaata aaaattattg cagaaccacc ggataagcgc cgccgtgacc tggacaacat 1548 0 tctgaaagca ccgctggatg cgctgacgca tgcggaagtg ctcattgatg acgagcagtt 1554 0 tgatgaaatc aatattgtgc gcggtcagcc tgtgccaggt ggacggctgg gcgtgaagat 1560 0 ttacgaaatc agaggtggta acgatggcgc gtgatatcca gatggttctt gagcgatggg 1566 0 gggcatgggc agcaaataat catgaagatg taacatggcc ctcgatagct gctggtttta 1572 0 aaggattaat cccgactaaa gtgaaatcac gtcctaagtg ttctgatgat gacgccatga 1578 0 taatttgtgg ttgtatggca cgattaaaca agaataatca gtatttgcac gatttgttgg 1584 0 tggattatta cgtaggtgga atgacattta tggctcttgc acgtaagcat agatgttctg 1590 0 atgggcttat tggtaaaagg ctttataaag cggaaggtat tattgaagga atgcttatgg 1596 0 ctctgaatgt ccggttagat atggatatgc ggtagggata tatagtgatg agggttatgt 1602 0 tttctgtgtt tataattaac atgtttattt tttgatggtc atgtattgtg gaaggtagat 1608 0 aaaatgttgc ctggtgaatt gaaaatattg ataatcaatc ttcatcatta aataaaagga 1614 0 gtgcttatgt ggattgtgtt agtactgtca ctgtcaactc tcagttggca taaggtagtg 1620 0 gctttttcat tgttgacggt gtctgttgtc ctggctgtgc ttaatgatat tattgattgg 1626 0 tcggtgttat tttttgttgc tacaatcgtt ttttttatta ttttgaagtt caactggaaa 1632 0 tataacgcct gggctaaatc tatatatgaa gttggcatag ttttatcagc catagcatta 1638 0 tttttccatc tatggccagg gtttcacaat cctgtagtgc taaattctgt tactgttggc 1644 0 cctcaaagta ctccctatac aatgtatttt aattttgata aagcgctggt gccatttttg 1650 0 ttagtcctgt gtacatcttc tttgtttaaa aaagaagtaa aatcagaagt gtctttgtgg 1656 0 aagtgggggg ctctgtcgct ctctgttcct cttatcctgt ttttggctgt tttttttggt 1662 0 ggattaaagc cagagattca ttttcctgag tggttgccag agtttatatt ggctaatttg 1668 0 ttttttgtgt ctctggcaga ggaatcatta tttagagggt atattcaatc acggctatca 1674 0 gaagtaacgt ctccattggt tgcattaatt gtggcggctt tgttgtttgg tttttatcac 1680 0 tattcaggtg gtgctttact tgtattattt gccacgttat ctggtgttgt gtatggattg 1686 0 tcatggatgt ggagtgggcg tttgtgggtt gccacccttt tccattttgg tttgaatctg 1692 0 tgtcacttgt tattctttac ctatccattt ttaaaacata attgattttt tctatggttt 1698 0 taaatttata agactgaaaa atagcaggac gtgacatttg catgaaaaat atgcacggca 1704 0 aagcatttac gtacgtaaaa aatcaggtat gctgttaaga gtggttattt cgccgcatag 1710 0 cttgaccccg cctctgagcg ggttttttgt gcccgcaaag tagcgcagtg cgttaaatgt 1716 0 gctggtagtt attaatacag gtctttcagc ttgctggctt tttcgacaag agttattggt 1722 0 gtgtcacgtt aaccggaaag ggtaaaaaga catgctgaaa cagcaggata tgacagaaac 1728 0 cgccagagtt gtgtttgatg aattaagcgt caccgaaccg gcgacggtcg gggagattgc 1734 0 gcagaatacg tacctttcac gcgagcgctg ccagttaata ctgacccagc tggttatgcg 1740 0 ggtctggcag actatcagtt cggttgttac agacgccttc agtcctgaag gcttttttat 1746 0 ttgtggtaaa tgggcggctg gtgggtgtta gcggcacctg tcagtccttt gcttatgtgt 1752 0 tgatgataat ttaccttttg gggctataat tgaactaacc aattgctaat gaaagtaaaa 1758 0 ttataatggt tgttgtctgt tcagttatca tggtttgctc cccaattaat atttttcttg 1764 0 aaaaggatac gttgtcactt aagcccggct cagtcgttct ggccaccaaa tgcatcaggg 1770 0 cgcttttcct tatgcattat ggcaaagtta aaattttcga tataaaccat tccatagtaa 1776 0 gtcaatatct ggaaattcag cataagctga caagaactca tctgactgac gttccgcttt 1782 0 atctgtcact ggaacccaac aaccctgcgt tggctgaggc tttaattacc agccagagat 1788 0 tttccggaga taccacggat atgtttctta tgatggcatg cctgtcgctg tttgaatcag 1794 0 atgaacggat attattattt ttaagtggat gtttatccag tataagtgcc aaagtcaggg 1800 0 cgataattca gacagatata tcagcaagct ggacgcttgg tgcgattgcg ttacgcctgc 1806 0 atatgagtga gagtttgtta aagataaaac tgaaaaatga agggcacatg ttcagtcgct 1812 0 tgttgctgga agagcggatg cgtgttgctg tcaatatgtt atgttcccgg catggatatg 1818 0 gacaggctgt agcagaaaaa tgcggttatt caagctggtc ctactttatt tctgtatttc 1824 0 accgctatta tggcttcccg ccagacagat atgtatccag gcaagggctt gattattgat 1830 0 tttcatctga ttattatttt ttgacccagc cctttagctc agtggtgaga gcgagcgact 1836 0 cataatcgcc aggtcgctgg ttcaaatcca gcaagggcca ccatcacata ccgccattag 1842 0 ctcatcagga aagagcgcca gctttcgaag ctggttgcgc ggagttcggg tccccgaagg 1848 0 cggtccatta tctgtatcct gcgttgttag ctcagccgga cagagcaatt gccttctaag 1854 0 caatcggtca ctggttcgaa tccagtacaa cgcgccacac ttattttccc tggctcgctt 1860 0 ttgcgggcct tttttttaaa tgtctcacaa ttcaggcggt tgactgttgt ctggtttgcg 1866 0 gggagtttgt taaaagaaac tggcatggtg aatccccctg tgcggagggg caatcagcga 1872 0 gtaggtatat gggataatcg cggattcagg tgctggtact gaattcaccg ggaggcaccc 1878 0 ggcaccatgc aatggcacat agcgccactc tccagcccct ctccggaggg gctttcttat 1884 0 ggacaaaaaa agcccgcgca gggagacgcg ggcggcaagg aataaacaac aaaacgtgaa 1890 0 gtaatatttc agctggcgaa taatatccga cagtaatcac tctgcgcaat agcgcggcct 1896 0 ttttcgtatt gcgggctgtt gtctctcttc tgccattgtc ctgtaacttc cggacttcag 1902 0 cccgctcctc attttactca caatattatc ccggccggga ggattcatgg catttaaaca 1908 0 ctatgatgtt gtcagggcgg cgtcgccgtc agaccttgcg gaaaagctga cacacaaact 1914 0 gaaagagggc tggcagccat acggcggacc ggttgccatt acgccgtaca cactgatgca 1920 0 ggcggtggct attgaaggag atccacaggt cggcccttca tctaagccgg actggttcta 1926 0 cgtggttgtg cttgccggac agtccaacgg catggcctac ggtgaagggc ttccgttacc 1932 0 ggattcttac gatgctccgg atccgcgcat taaacagctg gcgcgccgca gcacggtaac 1938 0 tccgggtgga gagagttgta cgtataacga catcattccg gccgaccact gcctgcatga 1944 0 tgtgcaggat atgagtacgc tgaatcatcc gaaggcagac ctgagcaaag ggcagtacgg 1950 0 ctgtgtcggc cagggcttac atattgccaa aaaactgctt ccgtatatcc cgaataacgc 1956 0 ggggatcctg ctggtaccat gctgtcgtgg tggttctgca ttcacccagg gcgctgaggg 1962 0 gacattcagt gcggacacgg gggccagcca ggattcggca cgctggggtg tgggtaaacc 1968 0 gttatatcag gacctgattg cgcgcactaa agctgcatta cagaagaacc cgaaaaatgt 1974 0 gttgctggcg gtgtgctgga tgcagggaga gtttgacatg agcgccgcca cccacgcaca 1980 0 gcaacctgcg ctgtttacag ccatgctgac acagtttcgt gctgacctct ccgtgtttaa 1986 0 cgcgcagtgc catggtggca gtgctgcaga tgtgccgtgg atttgtggtg atacgacgta 1992 0 ttactggaaa aatacatacg ctacccagta cgacaccgtg tacggcgggt ataaaaacag 1998 0 ggagagtgag ggcgtttatt ttgtgccctt catgacagac ggtaacggcg tcaataccgc 2004 0 cactaacgcg ccggcagaag atccggatat tccggcatca ggatattacg gtgcggcatc 2010 0 gagaacgaat ggaaaccagg tatcatcaaa ccgcccgaca catttcagtt catgggcgcg 2016 0 caggagcatt attccggatc gtctggcaac cgctattctg aacgcagccg ggcgcacctc 2022 0 cgccttcatc agtggtaagg caccggaaat caaaccctcg cccggcggca acacgccatc 2028 0 gggtccgtct gcagatacgt ccgttcgcac aatctccctg ctgccggcag ccggagaggc 2034 0 tgctgcgcag ggctggagca ttaaggatgg cggaattcag ttgtcagatg gtgtatttaa 2040 0 gatcaccagg cagagcaata aaacctggtc cctgacgcat ccggtggatg acgcaattac 2046 0 cctgctgaca cagggcggca gactgaactg taagttccgc ctgtcaggcg cactgaccaa 2052 0 caatcagttc gggctgggga tttatctgta tacggatgct cccgttcctg atggtgtggc 2058 0 gatgacgggt accggtaatc cgttcctgat gtcgtacttc actcagacca ctgacggcag 2064 0 agtgaatctg atgcatcaca ggaaagccgg aaacacgaag ctgggggagt tcggcgatta 2070 0 cggtaacgac tggcagacgc tggagctggt gttcaccgcc ggcagtgcca cggttactcc 2076 0 gaaactgaat ggagtggctg gcccggcatt ccaggttata aaagacagtc tgacactggg 2082 0 actgaatgcg ctgacgctga cggatgttac aaaaaatgca gcgtatggcg ttgagataga 2088 0 aagtctggtg ctggagataa atgcaccggc agcataataa aaaaagagcc agcgactgac 2094 0 ctgaaagaag acgctggcta aaaggcctta tatgtttgta gagacttatt tttcacagac 2100 0 agcaatgatg cctgtcaata tattatcaat atgcggattg aaccgccccg gaaatcctgg 2106 0 agactaaact ccctgagaaa gaggtaaaca ggatgactaa aaatactcgt ttttcccccg 2112 0 aagtccgtca gcgggcgatt cgtatggttc tggaaagtca ggatgaatat gactcacagt 2118 0 gggcggcaat ttgttccatt gccccaaaga ttggctgtac gccggagact ctgcgtgtct 2124 0 gggttcgcca gcatgagcgg gataccgggg gcggtgatgg tgggctcacc agcgctgaac 2130 0 gtcagcgtct gaaagagctg gaacgtgaaa atcgtgaact gcgccgcagt aacgatatcc 2136 0 ttcgccaggc ttccgcttat tttgcgaagg cggagttcga ccgcctctgg aaaaaatgat 2142 0 gccactgctg gataagctgc gtgagcagta cggggtcgga ccggtatgca gcgaactgca 2148 0 tattgccccg tcaacgtatt accattgtca gcaacagcga catcatccgg ataaacgcag 2154 0 tgcccgtgcg cagcacgacg actggctgaa gagagagata cagcgcgtat acgatgaaaa 2160 0 tcatcaggtg tacggtgtgc gtaaagtctg gcgtcagttg ttacgggaag gaatcagggt 2166 0 ggccagatgt acagtggcac gtctcatggc ggttatggga cttgccggtg ttctccgggg 2172 0 taaatgggcc cgtcgtccgt ctggcaccat ccatcacagc gataaaggct ctcagtatgt 2178 0 gtcactggcc tatacggagc gactaaaaga agccggatta ctggcatcaa cagggagtac 2184 0 aggcgactcg tatgacaacg cgatggctga gagcatcaat ggtctttaca aagcggaggt 2190 0 aatacaccgt aagagctgga aaaaccgtgc agaagtggaa ctggccacac taacgtgggt 2196 0 ggactggtat aacaatcgac gattgctggg aaggctgggc catactcctc cggcagaagc 2202 0 agaaaaagct tattatgctt ccatcggaaa cgatgatctg gcagcctgag ttcacagata 2208 0 aaacactctc caggaaaccc ggggcggttc attaattaat gaaaaatatt ctcaatttgt 2214 0 acccaacaaa gacaaacacg accagagcac ctgttcagac aggtttactt aaacgactta 2220 0 tatatgacac aaaaagcgac cactaaagtc gctttttctt atggtaacag gcaataacgc 2226 0 tctcagatat tttttagcat ttttttgacc gcgcgtttcc ggacgtattc tgttctcctg 2232 0 tccctttata tcgtcggaat acccgccgct cttcaaatcc cattcccaac tcagaatgta 2238 0 gtctgttgac cgcttgtttt atttcggtca ggttcaccgg tgaaaccgga gtccggcgcg 2244 0 ccttacgcaa acactctgct cgtttctgtg ccgccacttt tcttttctgg tcatcactta 2250 0 gctgtaccat cacttttgcc catcgttcag ctgctctccg gtacagtcct tttttctcca 2256 0 gacattctgc cacgtgatca tgtagcataa gtgacctccg attatctaca gactgccatc 2262 0 ctgaatttac cttcccttaa tgaaataaca ataaaaaaca aaccacgcaa aaacaataaa 2268 0 acaacacaca aaaaaaacta aataataaac aaaaataatc accttatttt attatttttt 2274 0 gagggagcaa ttactgaaca aaaaacgctg actatatact caaaaccaaa caactattct 2280 0 gccaatcagg tatcatggca acacacggaa ttaccgtgtt tttgccttct ctgcccatac 2286 0 aatacgggca tatacttcat tctctattgt aatatttcta tccatgtgcc ccactccatt 2292 0 tacctgtaaa taatattcaa aatatttatc acagaaatcg tttttggcca tgaactgagc 2298 0 acactataaa gtccggaact gactctttgt taaattacct taacgttacc agtaacaccc 2304 0 tcataacaaa acatcacggt atacactggg tacggatata ttcctgtgct ccttccagtt 2310 0 gcttctgcat tgccatcagc cgttctctga ggatgaaata atcccgttca gcggtgtctg 2316 0 ccagtcgggg gccggttgca ttatccacgc cggaggtgcc ggtggcttca cgcacggtac 2322 0 cggagcaggt ggcgttgatc cgcaggcgct tacgaccagc ggcaacatca gcacgcagag 2328 0 tttcattttc agctctcgca tcggctaatt ccctcgagta tctggcatca agtgcagcga 2334 0 catcacgctg gcgtatctgc atatcagtaa ttgtcgcgtt cgccagctcc agctcactgg 2340 0 cttttttatc gcgctgctct ttgtagatga tggcgtgatc acggtaatga ttcagcccca 2346 0 gactaagcgc accacaggcc accagcagga caatgataac cacacacaga acacggttca 2352 0 tatcaccacc aacggattgc ccagaccaga acagcaatgg ccacaatacg aatggcaaaa 2358 0 gctgccgctc ttgttaaatc cagactggct ggcgtctcca cttcaatgcc tttcataatg 2364 0 gacaacctca gaaagaatct tttatacttc ctcacaggga aagtacctcc ctacccataa 2370 0 tttctccctt gccttactca aggtcagaaa acacaaaacc ccgcttgctg ccaacaaacg 2376 0 gggtttttac ttttattcac ttaggtttta ccagttttca ggatttcgtg ttatccaccc 2382 0 gcgttggcca acgtcatttt tcaggaaaat attctgctat ctgtcgatgt cccagcacgc 2388 0 cagcgcgctc tcctggtcac gccgtgagac ctgaccgtag caattatttg aacggatacg 2394 0 gcagtctctg ccaccgtcct taatccacca gcgaatcgcc tcacaggcac cttttcgatc 2400 0 gcctgcatta attcgtttat aaaacgtcga cgggaagcac ttaccggggc caatgttgta 2406 0 cggacagaat gacgcgatcc ccgctttctg gggttcggtc agcggcaccc ggatgttttt 2412 0 ctccacccat gccagcgcct tgtcacgttc gatggcatta acccggtcgc atttttcctt 2418 0 tgacagcttc atgccaggaa taacaggctt accatccacc agaatggcac cacggcagat 2424 0 ggtccagatc cccgcaccat cacggtatgc cgtggtgtgg ttaccttcct tttcatccag 2430 0 aaactggtcg aggatttcag gcgcagaagc acctgcacca atcagcgcca gaacggcagc 2436 0 cgacaggccg tattttattt tttcgttcat ggggatttat cgatttctaa tcccttgata 2442 0 tgttaggtat ataatccaac actcatggtc gctctcataa acatatccct tgagacgcag 2448 0 cagattacaa caaatgaagc catataaatg aacagtaaag aaagtttgcg cagaagattt 2454 0 ttacaactaa tgacagaaaa cgttaaatca gagttacttc ttctgatggc agataataac 2460 0 gaagcaacaa gcagcattct tgcagaccct tacggtaaga tctcacataa aacgctggat 2466 0 attattacca caacattaac accgctgatg cttcaacggc tgaaacataa tatcaacgca 2472 0 tgggttaatg aagaattaag tcctccctgc ttatgggatt ctcgttacgc atgtcagcaa 2478 0 aaaatgcgaa ttttcaactt actatcacca aagctcaggt agccataaaa tcctgccctt 2484 0 catggcatac aggatttcaa tggaatcaca atgaccaact cttgcacagc tgtatccctg 2490 0 actccccgac aactcagatt ttcagtatct gctgctatct aaagagaaag cgcacaaatg 2496 0 caagggtctt tcatcacgtc ctgttattga ttgcctgtga ccttttctta cctcatggaa 2502 0 cgttttttca gttagaaata ttcattttac aaccagttcg tattgtttat tcatcgacta 2508 0 ctctccccgc gccaccttac gacggtcctc tctgattttg aaatacaggt tagtcagata 2514 0 cgtcagcagg ccaaacagca gacttcccag cactcctatt gccacccact gggacggaga 2520 0 gactttgtcc agcagctgca gtaaccagta ttccgtcccc accgctgacg tggtgtatga 2526 0 cacacctgtt gtgatttttt ccatctgatg tatgtctccg tcaccgccga cagaaaatga 2532 0 aagtaaagaa aaacaaaaaa gccgccagtg tcacccactg acggccaact ccgggagccg 2538 0 tgattatggc attcaggctc tgctaaaaat gccagataac attccggcct cccctgattc 2544 0 aggttataaa tgacacaata tcttgacaac acccgtcact gtctgtcaga aaatataccg 2550 0 ccaggcataa gtatcatgtg aaatccaact atccttctga gccagcacct ctccaccgaa 2556 0 agtcagtgct ggctgttttt ttccttaata aagcatctgt aactggttgt tgttctgcgg 2562 0 gttctgttct tcgttgacat gaggttgccc cgtattcagt gtcgctgatt tgtattgtct 2568 0 gaagttgttt ttacgttaag ttgatgcaga tcaattaata cgatacctgc gtcataatta 2574 0 attatttgac gtggtttgat ggcgtagatg cacgttgtga catgtagatg ataattatta 2580 0 tcattttgcg ggtcctttcc ggcgatccga caggttacgg ggcggcgacc tcgcgggttt 2586 0 tcgctattta tgaaaatttt ccgggatcca tgtccggttt ctcttcaagt taactatatg 2592 0 aaaaatataa aaacaggtct tctgtgaacc ggacatgaac aaaaaacaga catgtaaacc 2598 0 ggacatgacc ggttttgttg tgattgtgag gtgagagttt ttgcgaggtg aggagtggct 2604 0 acgcagactg aagttgccag gcatttaagt ctgaccgatc gccagcttcg cagattgcag 2610 0 aaattgccgg gtgccccgat atcgaataag cgagggcaac tggatctgga tgcctggcgc 2616 0 gatttttaca tatcgtatct gaggagaagt aaaaacgatg tgcctgatgg cgatagcgaa 2622 0 gacgactatg aggagaaatt gcttattgcc agatgggaac tgacagcaga acaggctgtt 2628 0 acacagcagt taaaaaagcg tacagcctga accgtctggt cagaatctga cgaattagac 2634 0 aaagtggtgt ccaccaaata agtagtggga accaaagtat cagatatgca gaaaaatgtg 2640 0 actcccggca ggcgaaaagg ctgccctaat tatcctcccg aatttaaaca gcagctcgtt 2646 0 gctgcctcct gtgaacccgg gatatccatc tcaaaacttg ctcttgaaaa tggcattaac 2652 0 gccaatctgt tgttcaaatg gcgacaacaa tggcgcgagg gaaagctgct attaccttct 2658 0 tcagagagcc cccagctact tcctgtgact ctcgatgcag ctgccgaaca gccagaatcg 2664 0 ctcgcagagg acccggaaac cctcagtatc agctgtgagg taacgttccg gcacgggacg 2670 0 ctccgcttca atggcaatgt cagcgaaaag ctcctgactc tgctgataca ggaactgaag 2676 0 cgatgatccc gttaccttcc gggaccaaaa tttggctggt tgccggtatc accgatatga 2682 0 gaaatggctt caacggcctg gctgcgaaag tacaaacggc gctgaaagac gatcccatgt 2688 0 ccggccatgt tttcattttc cggggccgca gcggcagtca ggttaaactg ctgtggtcca 2694 0 ccggtgacgg actgtgcctc ctgaccaaac ggctggagcg tgggcgcttc gcctggccgt 2700 0 cagcccgtga tggcaaagtg ttccttacgc aggcgcagct ggcgatgctg ctggaaggta 2706 0 tcgactggcg acagcctaag cggctgctga cctccctgac catgctgtaa atctctttat 2712 0 cctggttgtc acagaataag cccggtaaaa tacgggctta tgaacgacat ctcttctgac 2718 0 gacatcttcc tgctgaaaca gcgcctggcc gaacaggaag cgctgatcca cgccctgcag 2724 0 gaaaagctga gcaaccggga gcgcgaaata gaccatctgc aggcgcagct ggataaactc 2730 0 cgccggatga acttcggcag tcgttccgaa aaagtctccc gccgtatcgc acaaatggaa 2736 0 gccgatctga accggcttca gaaagagagc gatacgctga ctggtagggt gtatgacccg 2742 0 gcagtacagc gtccgttgcg tcagacccgc acccgtaagc cgttccctga atcactaccc 2748 0 cgtgacgaaa agcgactgtt gcctgcggcg ccgtgctgcc cgaactgcgg cggttcactg 2754 0 agctatctgg gcgaggatac cgccgaacag ctggagttga tgcgtagcgc cttccgggtt 2760 0 atccggacgg tacgggaaaa acatgcctgt actcagtgcg atgccatcgt gcaggcacct 2766 0 gcaccttcgc ggcccatcga gcggggtatc gccggaccgg ggctgctggc ccgcgtgctg 2772 0 acctcgaagt atgcagagca caccccgctg tatcgccagt cagaaatata cggccggcaa 2778 0 ggtgtggagc tgaggcgttc actgctgtcg ggctgggtgg atgcatgctg ccggctgctg 2784 0 tctccgctgg aagaggcgct tcatggctat gtcatgactg acggcaaact ccatgccgat 2790 0 gataccccgg tccaggtact gctgccgggt aataagaaga cgaagaccgg gcggttgtgg 2796 0 gcgtatgttc gtgatgaccg caatgcaggg tcagcgttgg cacctgcagt gtggttcgct 2802 0 tacagcccgg acagaaaagg catccatccg cagactcatc ttgcctgctt cagcggtgtg 2808 0 ctgcaagcgg atgcgtacgc cgggttcaac gagctgtatc gcaatggtgg gataacggaa 2814 0 gctgcctgct gggctcatgc ccgccgaaag atccacgatg tgcacgtccg catcccgtca 2820 0 gcactgacgg aagaagccct ggagcagatc ggtcagttgt acgccataga ggcggatata 2826 0 aggggaatgc cggcagagca gcggcttgct gaacgtcagc gaaaaacgaa accgttgttg 2832 0 aaatccctgg aaagctggtt gcgtgaaaag atgaagaccc tgtcgcgaca ctcagagttg 2838 0 gcgaaggcgt tcgcgtacgc acttaaccag tggccggcac tgacgtacta tgcgaacgat 2844 0 ggctgggtgg aaatcgacaa caacatcgct gaaaatgccc tgcgggcggt cagtctgggt 2850 0 cgtaaaaact tcctgttctt cggctctgat catggtggtg agcggggagc gctactgtac 2856 0 agcctgatcg ggacgtgcaa actgaatgac gtggatccag aaagctacct tcgccatgtg 2862 0 cttggcgtca tagcagactg gccggtcaac cgggtcagcg aactgcttcc gtggcgcata 2868 0 gcactgccag ctgaataaca catccccgtc aatacggccc tcgctgtacg cttacttaaa 2874 0 aaatgaggtg tcaaaaggaa aactgattga caccgggttc tgtatttttg ccctcagtaa 2880 0 gctggcaatg gcgttatcca gtacgcttga ttccatccct ttatccatgc agcgacagtt 2886 0 tcctgattta acaccgcgcc atcttgacca tctgaaaacc cttattgcta agggggcaaa 2892 0 tcagtgtgcg cgggcagggg ataaattacc ggatttactt gatgaatata tcagagcaac 2898 0 aactgaataa tatgatgagc gctgtcacaa ctgcattaca gcccctgata agggcattgc 2904 0 cggtgacgcc agttgaatgg gctgatcaaa attattatct gcctaaagaa tcttcatatg 2910 0 gtgagggcga atggaaaacg ctgccattcc agatcgccat catgaacagt atggggaatg 2916 0 atcagatccg cactgttaat ctgattaaat ctgcccgtgt tggctataca aagatgttgc 2922 0 tggggggggg cgggtatttt attgagcata aatcccgaaa cagtctgctt tttcagccca 2928 0 cggattctgc cgctgaagat tttatgaagt ctcacgtgga ggcgacgatt cggaacgtgc 2934 0 catgcctgaa agacctttcc ccatggctgg gtcgtaaaca tcgtgacaat actctcacgc 2940 0 tgaaacgctt ttcatcgggc gtcggtttct ggtgcctggg cggcgctgcc gccaaaaact 2946 0 accgtgaaaa atccgttgac gtggtctgct atgacgaact ttcctcgttc gagccggatg 2952 0 tcgaaaaaga gggctcgcca accctgctgg gggataagcg tattgagggg tcggtgtggc 2958 0 caaaatccat tcgcggctcg acgcctaaaa tcaaaggcac ctgccagatc gaaaaagccg 2964 0 ctaacgagtc ggcgcatttt atgcgttttt atgtgccctg cccgcactgt ggggaggcgc 2970 0 agtatctgaa atttggcgat gagtccacgc cttttgggct taaatgggag aaggacagcc 2976 0 ctgaaagtgt tttctacctc tgtgaacatc atggctgcgt gatccatcag tctgaactgg 2982 0 accagagcaa cgggcggtgg atctgtgaaa acacgggcat gtggacccgt gacggtctga 2988 0 cgtttttcag cgcccggggt gatgaaattc cgccgccgcg ctccatcatg ttccatatct 2994 0 ggacggcgta cagtccgttc accacctggg tacagattgt ctatgactgg ctggatgcac 3000 0 tgaaagatcc caacggcctg aaaacctttg tgaacaccac gctgggcgag acctgggaag 3006 0 aggccgtggg cgaaaaactc gatcaccagg tactgatgga taaggtggtg cgttacacgg 3012 0 cggcggtgcc tgcccgggtg gtttatctga cggcgggcat tgactcgcag cgaaaccgtt 3018 0 ttgagatgta tgtctgggga tgggctccgg gagaggaagc ctttctggtg gataaaatca 3024 0 tcattatggg gcgtcctgat gaggaagaga cgctgttacg tgtggatgcg gcgatcaaca 3030 0 aaaaataccg ccatgcggat ggcaccgaaa tgactatttc ccgtgtctgc tgggacaccg 3036 0 gggggatcga tggtgaaatt gtttatcaga gatcaaaaaa acacggtgtt ttccgggtgc 3042 0 tgccggtaaa aggcgcatct gtctatggca agccggtgat caccatgcca aaaacccgca 3048 0 atcagcgggg cgtgtatctg tgtgaagtgg gaacggacac cgcaaaagaa attctctatg 3054 0 cccgtatgaa agccgatccc tcgcctgcgg atgaagccac gtcgtatgcc atccgttttc 3060 0 ctgatgatcc ggagattttt tcgcagacag aggcgcagca actggtggcg gaagagctgg 3066 0 tggagaagtg ggaaaaagga aagatgcgtc tgctgtggga taacaaaaag cggcgtaacg 3072 0 aagcgctgga ctgcctggtg tatgcctacg cggcattacg tgtgtccgtg caacgctggc 3078 0 agcttgatct ggctgtactg gcaaaatccc gggaagaaga gacgacccgg ccaaccctga 3084 0 aagaactggc agcgaagctg tccggaggag tgaatggtta cagtcgctga actgcaggcg 3090 0 ctgcgtcagg cgcgccttga tttattaacc ggtaaacggg tggtgtctgt ccagaaagat 3096 0 ggtcgcagaa ttgaatatac ggcggcttct ctggatgagc ttaaccgggc gatcaatgat 3102 0 gcggagtcgg tactggggac aacccggcgt cgccgtcgtc cgctgggagt gaggttatga 3108 0 aacgaacgcc tgtcctgatt gatgtgaacg gcgttccgct tcgtgagagt ctcagctaca 3114 0 acgggggcgg tgcaggattt ggcgggcaaa tggcggagtg gttgccaccg gcgcagagtg 3120 0 ccgatgcggc cctgctgccc gcgttgcgtc tggggaatgc ccgggcagat gatctggtgc 3126 0 gcaataacgg aatagcggcc aatgcggtgg cactgcataa ggatcacatt gtcgggcata 3132 0 tgtttcttat cagctaccgt ccgaactggc gctggctggg gatgcgggag accgcagcaa 3138 0 aaagctttgt cgatgaggtg gaggcggcct ggtcggaata cgccgaaggg atgtctggcg 3144 0 agatcgacgt ggaaggaaaa cgcacgttca cggaatttat ccgtgaaggt gtgggcgttc 3150 0 atgcgtttaa cggcgaaatc tttgtgcagc cggtctggga tacggaaacc acgcagttat 3156 0 tccgtacgcg ttttaaagcc gtgagtccga aacgggtgga cacgccagga cacggtatgg 3162 0 ggaaccgttt tctgcgggcc ggggtggagg tcgatcgata tggccgtgcc gttgcgtacc 3168 0 atatctgtga ggatgatttt cctcgctccg ggagtggacg atgggaacgg atcccgcgtg 3174 0 aacttcccac cgggcgtccg gccatgctgc atattttcga gccggtggag gacgggcaga 3180 0 cccgtggggc caaccagttt tacagcgtca tggaacggct gaagatgctc gattccctgc 3186 0 aggcaacaca gcttcagtcg gccattgtga aagccatgta tgcagcgacg attgaaagtg 3192 0 accttgatac cgaaaaggcc tttgaatata tcgccggtgc gccgcagggg cagaaggata 3198 0 atccgcttat taatattctg gagaagttct ccagctggta tgacacgaat aacgtgacgc 3204 0 tgggtggtgt caaaattccg caccttttcc ccggggatga tctgaaacta cagactgcgc 3210 0 aggattcaga caatggattt tcggcgcttg aacaggcgct gctgcggtat atcgccgccg 3216 0 gtcttggcgt ttcctacgaa cagttgtccc gtgattactc gaaggtcagt tattcaagtg 3222 0 ccagggcctc tgccaatgag tcgtggcgct attttatggg gcggcgaaaa tttattgcgg 3228 0 cccggctggc cacgcagatg ttttcctact ggctggaaga ggcacttctt cgggggatta 3234 0 tccgtccgcc acgggcgcgt tttgattttt atcaggcgcg atcagcctgg tcacgggcag 3240 0 agtggattgg tgccggaaga atggccattg acgggctcaa ggaggttcag gaatcggtga 3246 0 tgcgcattga ggccggactg agcacgtatg agaaagagcc ggcgctgatg ggcgaggatt 3252 0 atcaggacat tttccgccag caggtcaggg aatctgcaga gcggcaaaaa gccggactct 3258 0 cacgtccggt gtggatagcg caggcgtatc agcagcagat agcggagagt cgcaggccgg 3264 0 aagaggagac aacaccccgt gagacgtaat ctttcacaca ttattgccgc agcattcaat 3270 0 gaaccgctgc ttctggagcc cgcctatgcg cgggttttct tttgcgcgct cgggcgcgag 3276 0 atgggggcag caagtctttc ggtaccacag cagcaggtac agcttgatgc tcccggaatg 3282 0 ctggctgaaa cggacgagta catggccgga ggtaaacgac cggcccgtgt ttaccgggtg 3288 0 gtgaacggta ttgctgtact gccggtgacc ggcacgctgg tgcaccggct ggggggtatg 3294 0 cggccatttt ccggaatgac aggctatgac ggcattgtcg cctgtcttca gcaggcaatg 3300 0 gcggatagcc aggtgcgggg cgtactgctg gacattgaca gtccgggcgg gcaggccgcc 3306 0 ggcgcgtttg actgcgctga catgatttac cgcctccgtc agcagaagcc ggtctgggca 3312 0 ctgtgcaatg acacggcctg ttctgcagcc atgctgctgg cgtcggcctg ctcccgacgg 3318 0 ctggttaccc agacatcccg tatcggctcc attggcgtga tgatgagcca tgtcagctat 3324 0 gccggtcatc tggcgcaggc cggtgtggat atcacgctga tttactcagg ggcgcacaag 3330 0 gtggatggca atcagtttga agccttaccg gcagaggttc gccagaacat gcagcagcgc 3336 0 attgatgcgg cgcgccggat gtttgccgaa aaagtggcca tgtttaccgg tctgtctgtt 3342 0 gatgccgtca cgggaacaga ggccgccgtt tttgaaggtc agtccggcat tgatgccggg 3348 0 ctggcggatg aattagtcaa tgcgtcggat gccatcagtg tgatggccac ggcgctgaac 3354 0 agtaatgtca gaggaggcac tatgccgcaa ttaactgcaa cggaagccgc cgcgcaggag 3360 0 aaccagcgag tgatggggat cctgacatgc caggaagcga aaggacgtga acagcttgcc 3366 0 acgatgctgg caggacaaca gggcatgagc gttgaacagg cccgggcgat tctggccgcg 3372 0 gcggcaccgc agcagccggt ggcatccacg cagagtgaag ccgatcgcat tatggcgtgt 3378 0 gaagaagcga acggtcgtga acaactggcg gcaacgctgg cggcgatgcc ggagatgacg 3384 0 gtggaaaaag cccgcccgat cctggctgct tcaccgcagg cggatgccgg accctcactc 3390 0 cgtgatcaga tcatggcact ggatgaggca aaaggggctg aggcgcaggc tgaacagctg 3396 0 gctgcctgcc cgggaatgac tgtggagagc gcccgggctg tgctggctgc gggatcaggt 3402 0 aaggcagaac cggtctctgc atccacaacc gccctgtttg aacgcatcat ggcgaaccat 3408 0 tcaccggctg cggtacaggg tggcgtgcca cagacgtcag cagacggtga tgcggacgtg 3414 0 aaaatgctca tggccatgcc atgaagtcag tgctgaccat caacaggagg tttttacaat 3420 0 atggtaacga aaaacatcac tgaacagcgt gcggaagtac gtatttttgc cggtaatgat 3426 0 ccggctcata cagccacagg cagcagcggg atttcctcgg caacaccggc actgacgccc 3432 0 ctgatgctgg atgaagccag cgggaaactg gtggtctggg acggacagaa agccggtagt 3438 0 gcagttggca tactggtact gccgcttgaa ggcacagaga cggtactgac ctattacaag 3444 0 tcggggacct ttgcgacgga ggcaatccgc tggcctgaaa gtgtggatga acacaaaaag 3450 0 gcaaatgcct ttgccggcag tgccctgagt cacgcggcgc tgccgtaaca cgttatcagg 3456 0 ccaccgcggt ggcctgactg atttctgaat gaaaggaact gatttatggg attgtttacg 3462 0 acccgccagt tactcggtta taccgaacaa aaagtgaaat ttcgtgcgct gtttctggag 3468 0 ctgtttttcc gccgtacggt gaatttccat accgaagagg tgatgctgga caaaattacc 3474 0 ggaaaaacgc cggtggcggc ctatgtctcc ccggttgttg aaggaaaagt gctgcgtcat 3480 0 cgcggtggtg aaacccgcgt gttacgtccg ggctacgtca agccgaaaca cgaattcccc 3486 0 tggagccggt aaaaggagcc ggtaccaccc tgtgggttta taacggtcag ggtgacgcct 3492 0 atgcaaaccc gttgtcagac gatgactggc agcgactggc taaggtgaag gatctgacgc 3498 0 cgggcgagat gacggcagaa tcctacgatg ataactacct ggatgatgaa gacgcggact 3504 0 ggaccgcgac cgggcagggg cagaaatctg caggtgatac cagttttacg ctggcctgga 3510 0 aaccgggaga ggaaggccag aaagggctta taggctggtt tgaaagcggc gatgtccggg 3516 0 cctataaaat ccgttttccg aatggcacgg tggatgtgtt tcgtggctgg gtcagcagta 3522 0 tcggtaaggc cgtgacggcg aaagaagtga tcacccgcac ggtgaaagtc actaacgtgg 3528 0 gtaaaccttc tgtagcggaa gaacgcagca aaattacgcc ggtcagtgcg attaaggtga 3534 0 cgccgacatc cggtacggtg gcaaaaggga aaacaaccac cctgacggtt tcttttgagc 3540 0 cggaaagtgc aacagacaag acgttcagag cggtttccgc cgatccgtcg aaagccacca 3546 0 ttagtgtgaa agatatgaca attacggtaa acggcgtggc gacaggtaag gtgcagatcc 3552 0 ctgtggtgag cggaaatggt cagttcgccg cagtggctga agtcaccgtt actgaagcgg 3558 0 gcgctgcagg gtaaacggag gtcatacatg tttctgaaaa cagaacaatt tgaatataac 3564 0 ggtgtgtctg tcacgctttc cgaattgtct gcgctgcagc gtatcgagca tcttgccctc 3570 0 ctgaaacggc gtgcagaaca ggcagaatcc agcggcaacc tgcaggtaag cgtggaagat 3576 0 ctcgtcagaa ccggcgcgtt tctggtggcg atgtccctgt ggcataacca tccacagaaa 3582 0 acgcagtcac cgtcaatgaa tgaggccgtg atgaagatag agcaggaagt gctcaccacc 3588 0 tggcctgccg atgccattgc ccgggcggaa gacgtggtgt tgtgcctgtc cgggatgagc 3594 0 ggggctgttc gtccggatac tgatattact gaagtggcga aaaataacac gctgactgat 3600 0 gatgattttt ctgcgggaaa gtcttcgacg gcgagctgaa ctttgccctc agactggcgc 3606 0 gtgagatggg gagacccgac tggcgcgcca tgcttgccgg gatgacatcc accgaatatg 3612 0 ccgactggca ccgtttttac cgcacgcatt attttcagga tacccagctg gatatgcatt 3618 0 tttccgggct gacgtacgct gtactcagcc tgtttttttg cgatccggat atgcatccct 3624 0 ctgatttcag tctgcttgtc ccccggcatg aggaagagca ggtggagagg ccggatgagg 3630 0 acaaaatgct gatgcagaaa gcggcaggac ttgccggagg cgtccggttc ggtggggacg 3636 0 gagggcgcga tattttatcg tctgcggatg tggcggatgt catggtggat gatgccgcat 3642 0 taatgatggc ttcagcgggg attccgggag gtgtgagata tgtcccagcc ggttggtgat 3648 0 cttgttattg acctgagtct ggatgctgtc cgtttcgatg agcagatgag ccgggtaagg 3654 0 cgtcattttt caggtctgga taccgacgtc agaaaaaccg ccagtgctgt tgaacagggc 3660 0 ctgagccgcc aggcgctggc tgcacaaaaa gccgggattt ccgtcgggca gtataaagcg 3666 0 gccatgcgaa ccctgcccgc acagtttacg gatatcgcca cgcagcttgc cggtggtcag 3672 0 aatccctggc tgatcctgct gcaacagggc ggtcaggtga aggactcctt cggcgggatg 3678 0 atccccatgt tcagggggct tgccggtgcg atcaccctgc cgatggtcgg ggtcacctcg 3684 0 ctggcggtgg cgacaggtgc gctggtgtac gcctggtacc agggagattc cacgctttca 3690 0 gcgtttaata aaaccctggt tctttccggt aatcagtccg gactgactgc cgatcgcatg 3696 0 ctgacgctct caagagccgg gcaggcagca gggctgacgt ttaaccaggc gagagagtca 3702 0 ctggcagccc tggtgaatgc cggtgtgcgt ggtggtgaac agtttgatgc catcaaccag 3708 0 agtgtcgcgc gttttgcttc tgcatccggt gtggaggtgg acaaggttgc agaggctttc 3714 0 ggaaaactga ccaccgaccc tacgtcgggg ctgattgcga tggtgcgcca gttccgtaac 3720 0 gtgacggcag agcagattgc gtatgttgcg cagctgcagc gttccggtga tgaggccggg 3726 0 gccttacagg cggcgaacga tatcgccacg aaaggctttg atgagcagac ccgtcgcctg 3732 0 aaagaaaaca tggggacact ggagacctgg gcggataaaa ccgggaaggc attcaaatcg 3738 0 atgtgggatg ccattctgga tatcggtcgt cctgagtcct cagcggatat gctcgccagt 3744 0 gcacagaagg catttgatga ggcggataaa aaatggcagt ggtaccagag ccggagccag 3750 0 cgccggggaa aaaccgcctc tttccgggcc aaccttcagg gcgcatggaa tgaccgggaa 3756 0 aatgcccgtc tggggctggc agcggccacg ctgcagtcgg atatggaaaa agccggtgaa 3762 0 ctggccgcca gggaccgggc cgaacgggac gcatcacagc tgaagtatac cggagaggcg 3768 0 cagaaggcgt atgagcgtct gctgacgccg ctggagaaat ataccgcccg tcaggaagaa 3774 0 ctgaataagg ccctgaaaga cgggaaaatc ctgcgggcgg attacaacac gctgatggcg 3780 0 gcggcgaaaa aggattatga atcgacgctg aaaaagccga agtcgtcagg agtcaaagtg 3786 0 tcagccggtg agcgtcagga agaccaggcg catgctgccc tgctggcgct tgaaaccgag 3792 0 ctcaggacgc tggaaaaaca cagcggtgcg aatgagaaaa tcagccagca gcgtcgcgat 3798 0 ttatggaaag cggaaaatca gtatgcggtc ctgaaagagg ctgccacgaa acggcagtta 3804 0 tctgagcagg aaaaattcct gctggcgcat aaagacgaga cgctggagta caaacgccag 3810 0 ctggctgagc tgggagacaa agttgaacac cagaaacgcc tgaatgagct ggcacagcag 3816 0 gcggtgcggt ttgaagagca gcagagcgcg aagcaggccg ccatcagcgc aaaagcccgc 3822 0 ggtctcactg accgtcaggc gcagcgggag tctgaagcgc agcgtcttcg ggacgtgtac 3828 0 ggtgataatc cggctgcgct ggcgaaggcc acatctgcac tgaagaacac ctggtctgcg 3834 0 gaggagcagc ttcgtggaag ctggatggcc gggctgaagt ccggctgggg cgagtgggcg 3840 0 gaaagtgcga cggacagttt ttcgcaggtt aaaagtgctg ccacgcagac ctttgacggt 3846 0 attgcacaga atatggcggc gatgctgacc ggtgcagagg cagactggcg gggattcacc 3852 0 cgttcggtgc tgtccatgct gacagagatt tttctgaagc aggcgatggt ggggatagtc 3858 0 gggagtatcg gcagcgccat tggcggtgct ttcggtggtg gtgcgtctgc ctccacgggg 3864 0 acggccattc aggctgcggc ggcgaacttc catttcgcga ccgggggatt tacggggacg 3870 0 gggggtaaat atgaacctgc gggaattgtt catcgcgggg agtttgtctt cacgaaggaa 3876 0 gcaaccagcc ggattggcgt cggcaacctg taccgcctga tgcgcggcta tgcggaaggt 3882 0 ggttatgtgg gtggtgccgg aagtccggcg cagatgcggc gggcggaagg tattaatttt 3888 0 aatcagaaca atcacgtggt gattcagaac gacggcacca acggacaggc ggggccgcag 3894 0 ctgatgaagg cggtgtatga catggcccgc aagggggcgc aggatgagct ccggctgcag 3900 0 ttgcgtgatg gcggtatgtt atcggggagc gggcgatgaa aacctttcgc tggaaagtga 3906 0 agccggatat ggaggtgaac tcgcagccat cggtgcgtga agtgcgtttt ggtgacgggt 3912 0 actcacagcg tatggcggca gggctgaatg ctgacctgaa aacataccgt gtgacgcttt 3918 0 ccgtgacccg ggaggaggcc cggcatctgg aagcgttcct ggcagagcac ggtggctgga 3924 0 aggcgtttct gtggacaccg ccttatgcct ggcggcagat aaaggtgacc tgtgccgcct 3930 0 ggtcatcacg ggttcgcatg ctgcgggttg aattcagtgc cgagtttaag caggtggtga 3936 0 actgatgcag gatattcacg aagaaagtct gaacgagtcg gttaaatcag agcagtcacc 3942 0 gcgggtggtg ctcagggaaa ttgacctgac ggtgcagggc ggtgagcggt attttttctg 3948 0 taatgagctg aatgaaaaag gggaggcggt cacctggcag gggcggcaat atcaggtata 3954 0 cccgattgac ggcagcggtt ttgagatgaa cgggaagggc agcagtgcca gaccgtcgct 3960 0 gacggtgtcc aatctgtttg gtctggtcac cgggatggcg gaggacctgc agagcctggt 3966 0 gggggccacg gtggtccgcc gccgggtgta tgcccgtttt ctggatgcgg tgaattttgt 3972 0 ggcgggcaat ccggaagcgg acccggagca ggagctgagc gaccgctggg tggtggagca 3978 0 gatgtcagag ctgacggcca tgacagcctc gtttgtgctg gccacaccga cggagacgga 3984 0 cggagcgctg tttcccggtc gcattatgct ggcgaatacc tgtatgtgga cctaccgctc 3990 0 tgatgagtgt ggttacacgg gcggggctgt ggcggatgag ttcgataaac ccaccaccga 3996 0 tatccgtaag gacagatgca gcaagtgcat gcgcgggtgt gagatgcgcg gcatggtggc 4002 0 taattttggc ggtttccttt ccattaataa actttcgcag taaatcccgg tttatgacac 4008 0 agactgaatc agcgattctg gcgcatgccc ggcggtgtgc gcctgcggag tcgtgcggct 4014 0 tcgtggtgag aacgccggag ggggagcggt atatcccttg tgtgaatatc tctgcagagc 4020 0 cggaggcgta ttttcgtatt gcaccggaag actggctgcg ggcagagatg cagggggaga 4026 0 ttgtggcact ggtccacagt catcccggtg gtctgccctg gctgagcgag gccgaccggc 4032 0 ggctgcagat aaaaagtgca ctgtcctggt ggctggtctg ccggggggaa attcataaat 4038 0 tccgctgtgt gccacatctg acaggacggc tctttgagca cggggtgacg gactgttaca 4044 0 cgctgttccg ggatgcatac catctggcgg gaattgatat gccggatttt gagcgtgagg 4050 0 atgactggtg gcgcaatggt cagaacctgt acctggacaa tatggaggcg actggttttt 4056 0 acaggatttc cctgccttcc gcacagcctg gcgatatcct gctgtgctgc tttggcgcat 4062 0 cggtggccaa tcatgccgcc atatactgcg gcaacggtga actgcttcac catctgcctg 4068 0 aacaactgag taaacgggag aggtattccg aaaaatggca acgacgaacg cattcagcct 4074 0 ggcgtcaccg ccactggcac gtatctgcct tcacggggat ttacaacgat ttggccgccg 4080 0 cctcagcctg tatgtgaaca cggcagcgga agccatccgt gccctgtcga tgcagatgcc 4086 0 gggattccgc cgtcagatga acgaaggctg gtaccagata cgtattgccg gtgatgacac 4092 0 ggcaccggag gcggtgtacg cccgtcttca cgaacagctg ggtgagggaa cggtcatcca 4098 0 tattgtgccg cgactggccg gggccggaaa gggtggactg cagattgtgc tgggggcggc 4104 0 agccatcgtg ggctctttct tcactgccgg ggcatcaatg gcgttatggg gttcagccct 4110 0 ggcagccggt ggtttttctg ccaccacgat gctgttttca cttggagcca gcatgattct 4116 0 gggcggtgtg gcccagatgc tggccccgaa ggcaaaaaca ccggattacc gcgcaacgga 4122 0 taacggcaga cagaacacgt acttttcctc gctggataac atgattgccc aggggaaccc 4128 0 gatgccggtg ccttacgggg aaatgctggt tggctcccgg cgaatctccc aggacatcag 4134 0 tacccgtgat gaaggcggtg acgggaaggt ggtggttatc gggcggcagg cataaaagcg 4140 0 aaaaaatccc gcagtgctca cggacaggaa ctgcgggagc gttacgaaga ttgagtgtaa 4146 0 ggaattattc ttatgtcacg acaaaaacat taactcagag agggaggatg tgccgttctt 4152 0 ttcagggaga aaggatttat cgtcctgagg aataaaggta aggggcccgc cccttacctg 4158 0 actgattatt gaatgatgcc gcaggccatt ctcgcaccac caccgcccag gggctccgga 4164 0 tggtcatgat ggttatcacc gccagcatga agcatgagag aacgcccttt aatctctttt 4170 0 aatgagttca gtctcggggc caggaccggg tagttcgctt ttccgtcatg cgtcacgaac 4176 0 agcgcaggga ggtcgcccgg gtgtccatcc ggagaccagg ggccaagatg tttgccggtg 4182 0 tttttcgggt caaagtgacc gccagccgat aatgctgcga ccggttttcc gtctttcagt 4188 0 gccggggcgc aatttccttt ttcgtgcaca tgaaaaccat gaatgccttc agacagagag 4194 0 tgaagggctg gtgtgaacag cagaccgtag ggggtctcct gaatggttat ttttccaatg 4200 0 ctgacttctt ttccgtcagc actgacaagg ttcattggga cttcctgttc tgctgcgtat 4206 0 ccgcatgatg ctgctgtcag catggcaatg gcagcaatga ttttacattt cataaaaccc 4212 0 tcattaattc cgttaacaga ctgagcttgc tggttacagg gtaacaaaca gcgttctgat 4218 0 gatatcgcgc aatagctgtg caatatccta tcactgcgat taataatacc aattgagagg 4224 0 aacattatgg gtaaaggtgg cggcagggcg cacacgccgg ttgaggcaaa ggacaatctt 4230 0 aagtccacgc agatgatgag cgtgattgat gccattggtg aagggccgat tgaaggtccg 4236 0 gtgaaggggc tgcagagtat cctggtgaac aaaaccccgc tgacggacac ggacggtaat 4242 0 cctgtgatac atggtgtgac cgcggtctgg cgcgccgggg agcaggagca gacaccacct 4248 0 gaaggctttg agtcctccgg ggcggaaacc gcactgggcg tggaagtgac gaaggcaaag 4254 0 ccggtgacgc gcaccattac gtccgcgaac attgaccgcc tgcgggtcac cttcggggtg 4260 0 cagtcactgt tggagaccac ctcaaagggc gaccgtaatc cctcttctgt ccgactgctg 4266 0 attcagttgc agcgtaacgg taactgggtg acggaaaagg atgtcaccat taacggcaag 4272 0 accacctcgc agtttctggc gtcggtgatt ctggataatc tgcctccccg tccttttaac 4278 0 atccggatgg tccgggagac ggcggacagc acctcggacc agctgcagaa taagacgctc 4284 0 tggtcgtcat acaccgaaat catcgatgtg aaacagtgct acccgaacac ggcgattgtg 4290 0 gggctgcagg tggatgcgga gcagtttggt ggccagcaga tgacggtgaa ctaccatatc 4296 0 cgaggtcgca tcatccaggt gccgtcaaac tatgacccgg aaaaacgcac gtacagcggc 4302 0 atctgggacg gcagcctgaa accggcatac agcaacaacc cggcctggtg cctgtgggac 4308 0 atgctgactc acccgcgcta cggcatggga aaacgcctgg gggcggcgga tgtggacaag 4314 0 tgggcgctgt atgccattgc gcagtactgc gaccagatgg tccctgatgg tttcgggggc 4320 0 acagagccgc ggatgacctt taatgcgtac ctgtcacaac agcgtaaggc gtgggacgtt 4326 0 ctcagtgatt tctgctcggc gatgcgctgt atgccggtat ggaacggcca gacgctgacg 4332 0 ttcgttcagg acagcccgtc ggatgtggtg tggccgtaca ccaacagtga tgtggtggtg 4338 0 gatgataacg gcgtggggtt tcgctacagc ttcagcgccc tgaaggaccg ccacacggcg 4344 0 gtggaggtga attacaccga cccgcagaac ggctggcaga cctccacgga actggtggaa 4350 0 gacccggaag ccatactgcg ctacgggcgc aacctgctga agatggatgc gttcggttgc 4356 0 accagtcgcg gtcaggccca ccgtgccggg ctgtgggtga taaagaccgg actgctggaa 4362 0 acgcagacgg tggatttcac gctcgggtca caggggctgc gtcacacacc cggtgacatt 4368 0 attgaaatct gtgataacga ctatgccggg accatgaccg gcggacgtgt cctgtccatc 4374 0 gatgccgcca gccgcaccct gacactggac cgtgaggtga ccctgccgga gaccggtgcc 4380 0 gccacggtga acctgattaa cggcagcggt aagccggtga gcgtggccat cactgcacac 4386 0 cccgcgccgg accggataca ggtcagcacc ctgccggatg gcgtggagac atacggtgtg 4392 0 tgggggctct ccctgccgtc actgcgtcgt cgcctgttcc gctgtgtctc catccgggaa 4398 0 aacacggacg gcacctttgc catcacggca gtgcagcacg taccggaaaa agaagccatc 4404 0 gtggataacg gtgcccgctt tgagccgcag tcaggcaccc tgaacagcgt catccctccg 4410 0 gcagtgcagc acctgacggt ggaggtgagc gcagctgacg gccagtatct ggcgcaggct 4416 0 aaatgggaca cgccgcgggt ggtgaagggc gtgcgcttca gtctgcgcct gaccagcgga 4422 0 agcggagaag gcagccgtct ggtgaccacc gccatcactg cggatacaga gcatcgttcc 4428 0 agtggtctgc cgccggggga atacaccctg acggtcaggg cgattaacag ttatggccag 4434 0 cagggggaac cggccaccac cacgttcagg attaatgcac ctgcggtacc cgccacgatt 4440 0 gagctgacac cgggctattt tcagataaca gcggtcccgc gtcttgcggt gtatgacccg 4446 0 acggtacagt ttgagttctg gttttcggag acaaaaatcg cagatacatc tcaggtggaa 4452 0 acctctgccc gttatctggg gaccggcagt cagtggagtg tatccggccc gcacattaag 4458 0 cccgggaagg atttctggtt ttacgtgcgc agcgtcaacc tggtggggaa atctgctttt 4464 0 gtggaagcca gtggccgggc cagcaatgat gcagaagggt atctggggct gtttcgggaa 4470 0 aaaataggaa aactgcatct ggctcagggg ctgtgggagc tgatagacaa cagccagctt 4476 0 gcggatgaga tggcggagat gaagacctcc atcaccgaaa cccgcaatga aatcacacag 4482 0 acggtcagta aaacgctgga ggaccagagc gccatcatac agcagataca gcgcgtgcag 4488 0 aaggacacaa atgatgacct tgctgcactt tacatgctga aggtacagaa aacaaaaaat 4494 0 ggcataccct atgttgccgg tattggagcg gggattgagg atactgatgg ccagcccctg 4500 0 agcaacatac tgctgctggc tgaccgtatt gcgatgatta acccggagga cggcaacacc 4506 0 acgccgttat ttgtggcgca ggggaatcag ttgttcatga acgatgtgtt cctgaaacga 4512 0 ctgtttgcgg tgagtatcac gtcatccgcc aatcccccga cgttttccct gacgccggag 4518 0 ggcaggctga ccgcaagaaa tgctgatatc agcggtaacg tgaatgcgaa ttccgggacg 4524 0 ctcaacaacg tcacgattaa cgagaactgt cgggttctgg gaaaactgtc cgcgaaccag 4530 0 attgaaggcg atctcgttaa aacagtgggc aaagctttcc cccgggattc ccgtgcaccg 4536 0 gagcggtggc catcagggac cattaccgtc agggtttatg acgatcagcc gtttgaccgg 4542 0 cagattgtta ttccggcggt ggcattcagc ggcgctaaac atgagagaga gcatactgat 4548 0 atttactcct catgccgtct gatagtgcgg aaaaacggtg ctgaaattta taaccgtacc 4554 0 gcgctggata atacgctgat ttacagtggc gttattgata tgcctgccgg tcacggtcac 4560 0 atgacgctgg agttttcggt gtcagcatgg ctggtgaata actggtatcc cacagcaagt 4566 0 atcagcgatt tgctggttgt ggtgatgaag aaagccaccg caggcatcag tatcagctga 4572 0 attttataac ccatatacgg gcgccagaaa tggcgccttt tttattgcag aaaagcgaga 4578 0 ggtaattatg cgtaaacttt atgccgccat tttgtccgca gccatttgtc tggccgtatc 4584 0 cggtgcgcct gcatgggcgt ctgaacatca gtcaacgctg agcgcggggt atcttcatgt 4590 0 ctcgacgaac gttcctggca gcgatgaact gaacgggatt aacgtgaaat accgttatga 4596 0 gtttacggac acactgggga tggtgacgtc gttcagctat gcaggagaca agaatcgcca 4602 0 gctgacccgt tacagcgata cccgctggca tgaagattcc gttcgtaacc gctggttcag 4608 0 cgtaatggcg gggccgtctg tgcgcgtgaa tgaatggttc agcgcgtatg cgatggcggg 4614 0 tgtggcttac agccgtgtgt cgactttctc cggggattat ctccgcgtaa ctgacaacaa 4620 0 ggggaaaacg catgatgtgc tgaccggaag tgatgacggt cgccacagca acacgtctct 4626 0 ggcgtgggga gctggcgtgc agtttaaccc gatcgaatcc gtggccattg atattgctta 4632 0 tgaaggctcc ggcagtggcg actggcgcac tgacggcttc atcgtgggtg tcggctataa 4638 0 attctgatta gccaggtaac acagtgttat gacagcccgc cggttcaggc gggctttttt 4644 0 gtggggtgaa tatggcagta aagatttcag gtgtactgaa agacggcaca ggaaaaccgg 4650 0 tagagaactg caccattcaa ctgaaagcca gacgtaacag cgccacggtg gtggtgaaca 4656 0 cggtggcctc tgaaaatccg gatgaagccg gtcgttacag catggacgtt gagtacggtc 4662 0 agtacagcgt tattctgttg gtggaagggt tcccgccgtc acatgccggg accatcaccg 4668 0 tgtatgaaga ttctcaaccg gggacgctga atgattttct cggtgccatg tcggaggatg 4674 0 acgtccggcc ggaggcactg cgtcgttttg aactgatggt ggaagaagcg gcgcgtcacg 4680 0 ctgaggaggc gaagaagaat gccggagagg cggagacgtc cgcgaggaat gccggcatat 4686 0 cagccagtca ggcagaagag agcgcggcaa atgctgacac ttcagcaggg gatgcatcgg 4692 0 agtcagcccg gcaggcggca gaaagtgcag ccgctgcaaa gcagtcagag gaggcgtcct 4698 0 cgtcctcggc ttctgcggcc gctcaaaaag ccagtgagtc atcacaaagt gcagcagaag 4704 0 ctgaattgtc aagaaagacg gcagaaagtg cagccggtaa tgcagccagg gatgcaacga 4710 0 ccgcaacaga aaaagcccgg gagtcagcag aaagcgcaca gtcagcggaa caaagcagga 4716 0 tagcggcgga agaagccgta aaccgaatcc ccaccgtggt gggacctccc gggccaaagg 4722 0 gggaaccggg tcccgcgggt cctcaggggc cgaagggaga taaaggagag cgtggcgaca 4728 0 ccggcccggc aggggcaacc ggcgaacggg gaccggcagg tgatgctggt ccggcaggcc 4734 0 cgcaggggcc gaaaggtgac aggggagagc ggggagagac cggtctgacg ggaaatgcag 4740 0 gtccacaggg tccaaaggga gacaccgggg cagcaggccc ggcaggccca cagggaccga 4746 0 aaggagaaac aggtgcggct ggcccggtgg gggcaaccgg acctcaggga ccgaagggcg 4752 0 acccggggga gacacaaatc cgttttcgtc tggggccggc gagcattatt gagacaaaca 4758 0 gccatggctg gttcccgggt acagatggtg cgctcatcac cggactgacc tttcttgccc 4764 0 ccaaagatgc cacacgggtt caggtttttt ttcagcattt gcaggtcagg tttggtgacg 4770 0 ggccgtggca ggatgttaag gggctggatg aagtgggcag tgatacaggc agaacaggag 4776 0 aatgacatga acatattaaa aaaaattatg cagcgtctgt gcggttgcgg aaagcatgat 4782 0 gactgtgaac acgggcagtc gcttacagta caactgcgac tggggccggc agacatcctg 4788 0 gagtcagatg agaatggcat tattccggag caggacgggg taatcacgca ggtggtgata 4794 0 ctggatgcag ataaaaagca gatacagtgt gtggtaagac cgctgcaaat tctgcgtgct 4800 0 gacgggaggt gggaaaatat tggcggaatg aaatagccga cagcttcaca aaaccggagt 4806 0 ccggctccgg ttttttgttg gttagatgta atctgacaga tacctgtata aataaccggt 4812 0 aactgtcagg tcagagctaa tataggtaat tatattataa tcacgagcgc ttagatgtat 4818 0 taatgccatg ctctgcaaga tgctgcatca gacgctgagc cacatcaggc aaaggtcttg 4824 0 attgttcatt ttgtactggc ggcgttggcg caggccagtt aggtgccgga ggaatatgtt 4830 0 cagccatatt ccgggctggt tgaatgccat gctctgcaag atgctgcatc agacgctgag 4836 0 ccacatcagg caaaggtctt gattgttcat tttgtactgg cggcgttggc gcaggccagt 4842 0 taggtgccgg aggaatatgt tcagccatat tccgggctgg ttgaatgcca tgctctgcaa 4848 0 gatgctgcat cagacgctga gccacatcag gcaaaggtct tgattgttca ttttgtactg 4854 0 gcggcgttgg cgcaggccag ttaggtgccg gaggaatatg ttcagccata ttccgggctg 4860 0 gttgaatgcc atgctctgca agatgctgca tcagacgctg agccacatca ggcagaggtc 4866 0 ttgattgttc attttgtact ggcggtggtg gcgcaggcca gttaggtgcc ggaggaatat 4872 0 gttcagccat actccgggct ggttgaatgc catgctctgc aagatgctgc accagacgct 4878 0 gagctacatc aggtagaggc cgatgtaaag cgtttttttc tatacttgac tgagtataag 4884 0 atgtgggacg ttgaagtcct gattctgtat aagaattttt taccttaaaa atagttgttg 4890 0 cactggcagg actgttgctg ggagaaaaag gtgagctggt ttttaccgtg ttaggtgtgc 4896 0 ttttgtgctg cgagacagtg aaggtactgc tgcgtatagc acttgatata ctgcgaggaa 4902 0 ggccggaaaa aaagaattaa tgctatttat catatagata accttataag agctttattg 4908 0 gatagtctta tttatccgtt tacatgaaat ctaccttttg tgaaattctc gtcaatattt 4914 0 tactcaaaat gatcggctgt aggaataaac tatttgatat tattacgttt ttagagttgt 4920 0 tttcaatcag ctatagatag ggcttggcgc cagaatggag aatatttaac gaggaataga 4926 0 agctttgtat cagacgggct tccctaaata gagaagttaa ataatcagga tgatgctaat 4932 0 gaatatcagg gacaaggtga gtgtcttcat gttcagtgaa acagggtgtc acaaaaaaga 4938 0 ttggggaggg ctagagcctt ctgcacgaaa atagtgatgc gacagatctg agatggcttt 4944 0 gtatccttct gcctggttca ggcctggagc agtccatgtt ttacaaaaat actcggcagc 4950 0 gtaacgtgtt gcaagagcgg catcagacga ggaacctgag gttccgctca tgaccgataa 4956 0 tctcatccga ataaaaatat accaattggt ataccaagtt tataccaaga gccaaaaaag 4962 0 caaaggggct accatttggt aaccccttga 4965 0 <210> 411 <211> 340 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(207..1226) <400> 411 Met Gly Arg Pro Arg Lys Asn Lys Lys Asp Asn Val Leu Pro Pro Arg 1 5 10 15 Val Arg Ser Asn Gly Tyr Ser Tyr Val Trp Lys Pro Glu Gly Ser Thr 20 25 30 Arg Ser Ile Gly Leu Gly Arg Val Arg Lys Thr Ser Val Ala Lys Val 35 40 45 Trp Gln Asn Tyr Glu Leu Glu Lys Ala Lys Leu His Asn Ile Met Thr 50 55 60 Val Ala Lys Leu Trp His Met Phe Met Asp Ser Pro Ala Phe Thr Glu 65 70 75 80 Leu Ala Pro Arg Thr Gln Lys Asp Tyr Arg Gln His Gln Lys Ala Leu 85 90 95 Leu Met Val Phe Gly Lys Val Leu Ala Asp Asn Val Lys Thr Glu Gln 100 105 110 Val Arg Ile Phe Met Asp Lys Arg Gly Leu Glu Ser Lys Thr Gln Ala 115 120 125 Asn His Glu Leu Ala Ser Leu Ser Arg Val Tyr Gly Trp Gly Tyr Glu 130 135 140 Arg Gly Tyr Val Lys Asn Asn Pro Cys Lys Gly Val Arg Lys Phe Ser 145 150 155 160 Leu Lys Ala Arg Thr Val Tyr Ile Thr Asp Glu Gln Tyr Ala Ala Ile 165 170 175 Tyr Ala Glu Ala Ile Pro Gln Leu Arg Ile Ala Met Glu Ile Ser Tyr 180 185 190 Leu Cys Ala Ala Arg Leu Gly Asp Val Leu Glu Leu Lys Trp Gln Asp 195 200 205 Ile Met Asp Lys Gly Ile Tyr Ile Glu Gln Asn Lys Thr Gly Thr Lys 210 215 220 Gln Ile Lys Glu Trp Ser Pro Arg Leu Arg Thr Ala Ile Gln Leu Ala 225 230 235 240 Arg Asn Val Ser Ser Cys Thr Cys Glu Tyr Val Ile Asn Thr Thr Lys 245 250 255 Gly Gly Lys Val Ile Ala Lys Thr Leu Asn Asn Trp Trp Asn Gln Ala 260 265 270 Lys Arg Ala Ala Glu Gln Lys Val Gly Val Pro Phe Gly Cys Asn Phe 275 280 285 His Asp Ile Lys Ala Lys Gly Ile Ser Asp Tyr Glu Gly Ser Ser Arg 290 295 300 Asp Lys Gln Ile Phe Ser Gly His Lys Thr Glu Asn Gln Val Leu Ile 305 310 315 320 Tyr Asp Arg Lys Thr Lys Ile Thr Pro Thr Leu Asp Leu Pro Leu Val 325 330 335 Val Ser Lys * <210> 412 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1319..1471) <400> 412 Met Gly Ser Phe Leu Gly Pro Ile Thr Asn Gly Met Pro Cys Ser Leu 1 5 10 15 Asn Trp Cys Cys Cys Phe Val Tyr Arg Ser Tyr Phe Val Ile Ser Leu 20 25 30 Ile Ser Ala Gly Asp Arg Val Asn Ser Tyr Met Trp Ser Arg Ala Phe 35 40 45 Thr Ala * 50 <210> 413 <211> 824 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1514..3985) <400> 413 Met Ser Lys Ile Phe Ile Cys Ala Ala Ile Pro Asp Glu Gln Ala Ile 1 5 10 15 Lys Glu Asp Ser Ala Val Ala Val Ala Thr Ala Ile Glu Ala Gly Asp 20 25 30 Glu Arg Arg Ala Arg Ala Lys Phe His Trp Gln Phe Leu Glu Gln Phe 35 40 45 Pro Ala Ala Gln Asp Cys Ala Tyr Lys Phe Ile Val Cys Glu Asp Lys 50 55 60 Pro Gly Ile Pro Arg Pro Ala Leu Asp Ser Trp Asp Thr Glu Tyr Met 65 70 75 80 Gln Glu Asn Arg Trp Asp Glu Glu Ser Ala Ser Phe Val Pro Val Glu 85 90 95 Pro Glu Ser Asp Pro Met Asn Val Asn Phe Asp Lys Leu Ser Pro Glu 100 105 110 Val Gln Asn Ala Val Leu Val Lys Phe Asp Thr Cys Glu Asn Ile Thr 115 120 125 Val Asp Met Val Ile Ser Ala Gln Glu Leu Leu Gln Glu Asp Met Ala 130 135 140 Thr Phe Gly Gly His Ile Val Glu Ala Leu Met Lys Met Pro Glu Val 145 150 155 160 Asn Ala Met Tyr Pro Glu Leu Lys Leu His Ala Ile Gly Trp Val Lys 165 170 175 His Lys Cys Glu Pro Gly Ala Lys Trp Pro Glu Ile Gln Ala Glu Met 180 185 190 Arg Ile Trp Lys Lys Arg Arg Glu Gly Glu Arg Lys Glu Thr Gly Lys 195 200 205 Tyr Thr Ser Val Val Asp Leu Thr Arg Ala Arg Val Asn Gln Gln Asn 210 215 220 Thr Glu Asn Ala Ala Glu Lys Thr Gly Ala Val Thr Val Ala Ile Arg 225 230 235 240 Arg Glu Tyr Lys Gln Thr Trp Lys Thr Leu Asp Asn Glu Leu Ala Cys 245 250 255 Ala Leu Trp Pro Gly Asp Val Asp Ala Gly Asn Ile Asp Gly Thr Ile 260 265 270 His Arg Trp Ala Thr Asn Glu Val Ile Asp Lys Asp Arg Glu Asp Trp 275 280 285 Lys Arg Ile Ser Ala Ser Met Arg Lys Gln Pro Glu Ala Leu Gly Tyr 290 295 300 Asp Arg Gln Thr Ile Phe Gly Leu Val Arg Glu Arg Pro Ile Asp Ile 305 310 315 320 His Lys Asp Pro Val Ala Leu Asn Lys Tyr Ile Ser Glu Tyr Leu Thr 325 330 335 Thr Lys Gly Val Phe Glu His Glu Glu Thr Asp Gln Ser Ser Thr Asp 340 345 350 Ala Leu Gln Pro Ser Ala Ala Gln Thr Ala Pro Val Glu Thr Ala Glu 355 360 365 Ser Asp Thr Gln Lys Asn Glu Ile Leu Val Glu Ala Glu Pro Ser Val 370 375 380 Glu Arg Glu Gly Pro Phe Tyr Phe Val Phe Thr Asp Lys Gly Gly Glu 385 390 395 400 Lys Tyr Gly Arg Ala Asn Lys Leu Ser Gly Leu Asp Lys Ala Leu Ala 405 410 415 Ala Gly Gly Thr Glu Ile Ser Lys Glu Glu Tyr Phe Ala Arg Lys Asn 420 425 430 Gly Thr Tyr Thr Gly Leu Pro Gln Asn Val Asp Thr Ala Glu Asp Ser 435 440 445 Glu Gln Ser Glu Pro Val Lys Val Thr Ala Asp Glu Val Asn Lys Ile 450 455 460 Met Gln Ala Ala Asn Ile Ser Gln Pro Asp Ala Asp Lys Leu Leu Ala 465 470 475 480 Ala Ser Arg Gly Glu Phe Val Glu Gly Ile Ser Asp Pro Asn Asp Pro 485 490 495 Lys Trp Val Lys Gly Ile Gln Ser Arg Asp Ala Glu Asp Gln Asn Gln 500 505 510 Pro Asn Val Lys Gln Asn Glu Pro Glu Ala Glu Gln Asn Ser Pro Asp 515 520 525 Thr Gln Gln Asn Gly Pro Glu Glu Gln Gln Pro Glu Pro Ala Val Gln 530 535 540 Gln Glu Leu Glu Lys Val Cys Thr Ala Cys Gly Gln Thr Gly Gly Gly 545 550 555 560 Asn Cys Pro Asp Cys Gly Ala Val Met Gly Asn Ala Thr Tyr Leu Glu 565 570 575 Thr Phe Asp Glu Glu Asn Gln Ala Glu Ala Gln Lys Asn Asp Pro Glu 580 585 590 Glu Met Glu Gly Thr Glu His Leu His Lys Glu Asn Thr Gly Ser Asp 595 600 605 Gln Tyr His Ala Ser Asp Asn Lys Thr Gly Glu Thr Ala Asn Pro Leu 610 615 620 Ile Lys Val Asn Gly His His Glu Ile Ser Ser Thr Ser Arg Leu Trp 625 630 635 640 His His Leu Met Ile Asp Leu Glu Thr Met Gly Lys Asn Pro Asp Ala 645 650 655 Pro Ile Asn Ser Ile Ala Gly Lys Phe Phe Asp Pro Ala Thr Gly Glu 660 665 670 Met Gly Pro Glu Phe Ser Lys Thr Ile Asp Leu Glu Thr Ala Gly Gly 675 680 685 Val Ile Asp Arg Asp Thr Ile Lys Trp Trp Leu Lys Gln Ser Arg Glu 690 695 700 Ala Gln Ser Ser Ile Leu Thr Asp Glu Ile Thr Leu Asp Asp Ala Leu 705 710 715 720 Leu Gln Phe Arg Glu Phe Ile Asp Glu Asn Ser Gly Glu Phe Phe Val 725 730 735 Gln Val Trp Gly Asn Gly Ala Thr Phe Asp Asn Val Ile Leu Arg Arg 740 745 750 Ser Tyr Glu Arg Gln Gly Ile Pro Cys Pro Trp Arg Tyr Thr Asn Asp 755 760 765 Arg Asp Val Arg Thr Met Val Ala Leu Gly Leu Val Met Asp Phe Asp 770 775 780 Ala Arg Thr Thr Ile Pro Phe Glu Gly Glu Arg His Asn Ala Leu His 785 790 795 800 Asp Ala Arg Tyr Gln Ala Lys Tyr Val Ser Ala Ile Trp Gln Lys Leu 805 810 815 Leu Pro Ser Gln Ala Asp Phe * 820 <210> 414 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4079..4270) <400> 414 Met Asn Thr Thr Phe Ala Leu Val Leu Thr Val Tyr Leu Val Ser Gly 1 5 10 15 Glu Ser Leu Glu Leu Val Thr Gly Leu Tyr Gly Ser Met Lys Glu Cys 20 25 30 Met Ala Ala Ala Ala Glu Gln Lys Ile Pro Gly Asn Cys Tyr Pro Val 35 40 45 Asp Lys Thr Thr His Thr Asn Asn Asn Glu Ile Pro Ala Gly Leu * 50 55 60 <210> 415 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4267..4455) <400> 415 Met Glu Lys Leu Ser Cys Asn Ala Ser Thr Ser Glu Leu Arg Phe Glu 1 5 10 15 Ile Gly Val Ile Thr Gly Asp Lys Thr Phe Ile Glu Asp Ala Ile Lys 20 25 30 Gln Arg Lys Leu Glu Gln Asp Leu Leu Asn Glu Val Cys Ile Pro Ser 35 40 45 Met Leu Ala Arg Leu Asp Leu Leu Gln Lys Gly Tyr Lys Gln * 50 55 60 <210> 416 <211> 102 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4722..5027) <400> 416 Leu Ser Leu Lys Arg Met Val Asn Leu Thr Thr Arg Cys Pro Gln Arg 1 5 10 15 Gly Lys Asn Asn Pro Ala Ile Leu Thr Ala Ala Pro Phe Arg Gly Leu 20 25 30 Pro Gln Pro Glu Ala His Gly Arg Ile Lys Phe Asn Asp Gly Ser Lys 35 40 45 Gly Glu Gly Leu Arg Arg Ala Leu Ser Cys Tyr Ala Leu Thr Phe Gln 50 55 60 Gly Tyr Ile Leu Ser Val Asn Cys Gln Cys Arg Ile Leu Ile Cys Val 65 70 75 80 Arg Arg Thr Thr Thr Arg Ser Ser Val Leu Val Ser Ile Phe Asn Ser 85 90 95 Ala Leu Asn Gly Gly * 100 <210> 417 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5029..5214) <400> 417 Met Pro Asn Lys Pro Cys Pro Ala Cys Asn Ala Leu Ser Gly Phe Leu 1 5 10 15 Glu Lys Gly Gly Tyr Tyr Ile Phe Asn Cys Pro Glu His Val Glu Phe 20 25 30 His Ile Ser Lys Leu Asp Ser Ile Ile Thr Lys Pro Asn Gln Tyr Gln 35 40 45 Ser Asp Leu Leu Asn Lys Glu Leu Asn Ala Ala Arg Asp * 50 55 60 <210> 418 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5252..5404) <400> 418 Met Lys Gly Thr Ala Ser Ala Asp Phe Thr Tyr Ser Met Met Ala Ala 1 5 10 15 Asp Gly Glu Pro Phe Pro Pro Glu Leu Lys Ile Thr Pro Gly Asn His 20 25 30 Pro Met Val Thr Ile Arg Ala Ile Glu Asn Tyr Trp Phe Asn Pro Val 35 40 45 Gln Gln * 50 <210> 419 <211> 130 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5401..5790) <400> 419 Met Glu Phe Lys Asp Leu Leu Lys Glu Ile Gln Glu Ile Ala Ala His 1 5 10 15 Ala Leu His Gln Arg Leu Asn Glu Val Glu Leu Glu Ser Ala Thr Lys 20 25 30 Lys Tyr Ile Asp Asn Met Ala Arg Asn Val Arg Asp Ala Phe Thr Gly 35 40 45 Leu Tyr Ser Val Ser Val Thr Asn Asn Gln Asn Thr Glu Glu Thr Ala 50 55 60 Lys Arg Ile Ala Ser Val Met Gly Phe His Val Glu Glu Lys Tyr Ser 65 70 75 80 Lys Lys Glu Phe Trp Lys Thr Thr Lys Lys Leu Gln Ser Glu Asn Cys 85 90 95 His Leu Leu Arg Gln Ser Leu Leu Ser Met Arg Lys Val Ile Gln Met 100 105 110 Thr Gln Asp Tyr Arg Asn Cys Ser His Tyr Leu Lys Asn Ser Glu Leu 115 120 125 Ser * <210> 420 <211> 43 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5802..5930) <400> 420 Met Asp Phe Asp Thr Ile Met Glu Lys Ala Tyr Glu Glu Tyr Phe Glu 1 5 10 15 Gly Leu Ala Glu Gly Glu Glu Ala Leu Ser Phe Ser Glu Phe Lys Gln 20 25 30 Ala Leu Ser Ser Ser Ala Lys Ser Asn Asp * 35 40 <210> 421 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5932..6087) <400> 421 Met Asp Thr Ile Asp Leu Gly Asn Asn Glu Ser Leu Val Tyr Gly Val 1 5 10 15 Phe Pro Asn Gln Asp Gly Thr Phe Thr Ala Met Thr Tyr Thr Lys Ser 20 25 30 Lys Thr Phe Lys Thr Glu Asn Gly Ala Arg Arg Trp Leu Glu Arg Asn 35 40 45 Ser Gly Glu * 50 <210> 422 <211> 73 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6145..6363) <400> 422 Leu Asn Asn Phe His Thr Pro Ser Phe Glu Gly Phe Phe Cys Pro Lys 1 5 10 15 Gln Gln Leu Lys Thr Val Asp Thr Lys Thr Val Phe Tyr Cys Arg Leu 20 25 30 His Thr Pro Thr Thr His Pro Ala Pro Gln Asn Ala Gly Gln Tyr Phe 35 40 45 Glu Leu Pro Ser Ser Gly Gln Gly Val Ser Ser Gln Pro Glu Ala Tyr 50 55 60 Glu His Asp Gly Arg Val Gln Leu * 65 70 <210> 423 <211> 96 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6365..6652) <400> 423 Met Leu Pro Ile Leu Trp Leu Pro Ser Ala Arg Asp Asp Leu Arg Gln 1 5 10 15 Ile Ile Thr Tyr Ile Ala Lys Glu Asn Pro Pro Ala Ala Arg Arg Leu 20 25 30 Lys Ile Arg Ile Glu Thr Ser Val Leu Pro Leu Ser Glu His Pro Tyr 35 40 45 Leu Tyr Pro Pro Ser Glu Arg Val Ser Gly Leu Arg Glu Ile Val Thr 50 55 60 His Pro Asn Tyr Ile Ile Leu Tyr Arg Val Ala Ala Ser Ser Ile Glu 65 70 75 80 Ile Val Ser Val Thr His Ser Arg Arg Gln Phe Pro Phe Ser Ile * 85 90 95 <210> 424 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6652..6843) <400> 424 Met Gly Thr Ala Leu Ser Pro Ile Val Ser Glu Phe Glu Thr Thr Glu 1 5 10 15 Gln Glu Asn Ser Tyr Asn Glu Trp Leu Arg Thr Lys Val Thr Ser Ser 20 25 30 Leu Ala Asp Thr Arg Pro Ala Ile Pro His Asp Glu Val Met Ala Glu 35 40 45 Met Glu Asn Leu Ile Ala Gln Ile Ala Val Thr Asn Lys Ser Glu * 50 55 60 <210> 425 <211> 126 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6871..7248) <400> 425 Met Tyr Arg Ile Ser Lys Leu Leu Gln Glu Thr Gly Trp Ser Gln Ala 1 5 10 15 Glu Leu Ala Arg Arg Ile Gly Val Thr Gln Gln Thr Val Gln Gln Trp 20 25 30 Val Ser Gly Lys Ala Thr Pro Lys Ala Ser Ser Leu Asp Lys Leu Val 35 40 45 Glu Val Ser Gly His Pro Leu His Trp Phe Leu Leu Pro Pro Glu Glu 50 55 60 Cys Glu Gln Ile Phe Thr Pro Asp Thr Met Lys Ile Gly Pro Arg Gln 65 70 75 80 Arg Glu Leu Leu Gln Ala Phe Ser Ala Phe Pro Glu Glu Asp Gln Glu 85 90 95 Lys Met Leu Gln Glu Ile Lys Asp Lys Lys Lys Ser Met Glu Glu Thr 100 105 110 Ile Ala Arg Trp Leu Ala Ala Gln Lys Ser Arg Arg Ala * 115 120 125 <210> 426 <211> 91 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7381..7653) <400> 426 Met Leu Asp Ser Thr Arg Glu Lys Ile Arg Gln Lys Tyr Thr Gln Ala 1 5 10 15 Glu Ile Gly Arg Tyr Met Gly Val Ala Gln Gln Thr Val Trp Gln Trp 20 25 30 Phe Ser Phe Gly Val Pro Pro Lys Gln Val Ile Pro Leu Cys Gln Leu 35 40 45 Met Lys Trp Glu Val Thr Pro His Glu Ile Arg Pro Asp Ile Tyr Pro 50 55 60 Asn Pro Thr Asp Gly Leu Pro Val Gly Cys Lys Val Asn Thr Ser Asn 65 70 75 80 Ala Pro Glu Leu Ile His Glu Asn Gln Ala * 85 90 <210> 427 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7637..8062) <400> 427 Met Lys Ile Lys His Glu His Ile Arg Met Ala Met Asn Ala Trp Ala 1 5 10 15 His Pro Asp Gly Glu Lys Val Pro Ala Ala Lys Ile Thr Lys Ala Tyr 20 25 30 Phe Glu Leu Gly Met Thr Phe Pro Glu Leu Tyr Asp Asp Ser His Pro 35 40 45 Glu Ala Met Ala Arg Asn Thr Gln Lys Ile Phe Arg Trp Val Glu Lys 50 55 60 Asp Thr Pro Asp Ala Val Lys Lys Ile Gln Ala Leu Leu Pro Ala Ile 65 70 75 80 Glu Lys Ala Met Pro Pro Pro Leu Val Ala Arg Met Arg Ser His Ser 85 90 95 Ser Ala Tyr Phe Arg Glu Leu Val Glu Thr Lys Glu Arg Leu Val Lys 100 105 110 Asp Ile Asp Asp Phe Val Ala Ser Ala Ile Val Leu Phe Asp Gln Met 115 120 125 Asn Arg Gly Gly Pro Ala Gly Asn Thr Leu Ala Val His * 130 135 140 <210> 428 <211> 152 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8269..8724) <400> 428 Met Tyr Phe Leu Lys Ser Leu Tyr Gln Ala His Val Leu Asn Val Ala 1 5 10 15 Ala Thr Asn Arg Trp Cys Asn Ser Pro Glu Met Leu Pro Asp Tyr Arg 20 25 30 Ala Trp Leu Arg Ala Glu Thr Tyr Leu Arg Leu Asp Ile Leu Ile Ser 35 40 45 Glu Leu Gln Lys Glu Thr Ala Ser Ile His Asn Leu Gln Gly Ile Asp 50 55 60 Ala Val Arg Ile Leu Val Ser Arg His Ser Ala Leu Ser Ile Ile Glu 65 70 75 80 Val Arg His Leu Ser Phe Ser Glu Leu Ile Phe Leu Leu Gln Pro Ala 85 90 95 Leu Glu Ser Ala Asn Ile Pro Pro Glu Val Ile Gln Tyr Pro Pro His 100 105 110 Val Asp Glu Gln Leu Gln Asp Val Pro Tyr Asn Gln Arg Ala Gly Leu 115 120 125 Thr Pro Cys Ser Glu Ala Glu Trp Asp His Ser Leu Leu Lys Lys Tyr 130 135 140 Gln Asp Leu Tyr Asn Pro Gln * 145 150 <210> 429 <211> 364 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8803..9894) <400> 429 Met Arg Asp Tyr Ala Lys Val Ser Pro Arg Phe Trp Leu Gly Glu Thr 1 5 10 15 Gly Arg Glu Leu Arg Lys Ala Gly Ala Glu Ala Gln Val Val Ala Phe 20 25 30 Tyr Leu Met Thr Ser Pro His Ala Asn Met Leu Gly Leu Tyr Tyr Leu 35 40 45 Pro Val Leu Tyr Leu Ala His Glu Thr Gly Leu Gly Leu Glu Gly Ala 50 55 60 Ser Lys Gly Leu Lys Arg Ala Val Glu Ala Gly Phe Cys Ser Tyr Asp 65 70 75 80 His Asp Ala Glu Met Val Trp Val His Glu Met Ala Ala Trp Gln Val 85 90 95 Gly Glu Thr Leu Lys Pro Gly Asp Asn Arg Cys Ala Gly Val Arg Asn 100 105 110 Glu Tyr Ala Ser Leu Pro Glu Asn Ala Phe Leu Ser Val Phe Tyr Asp 115 120 125 Arg Tyr Lys Thr Asp Phe His Leu Asp Val Arg Arg Asn Asn Ser Arg 130 135 140 Asn Ser Val Arg Gly Phe Glu Gly Ala Phe Lys Gly Leu Arg Ser Gln 145 150 155 160 Glu Gln Glu Gln Glu Gln Glu Lys Glu Gln Glu Gln Asp Lys Asn Thr 165 170 175 Met Val His Gly Lys Lys Asn Thr Thr Asn Gln Ala Gly Asp Val Gln 180 185 190 Thr Val Asn Pro Gly Gln Pro Ala Gly Thr Thr Pro Glu Ala Asp Ser 195 200 205 Gly Ala Val Gln Gln Val Met Thr Ala Gly Ser Glu Gln Ser His Gln 210 215 220 Leu Gln Gln Pro Glu Ala Asp Ser Ala Ile Gln Arg Glu Ala Asp Arg 225 230 235 240 Val Val Pro Glu Ser Thr Gly Gln Ser Val Gly Arg Val Asp Tyr Pro 245 250 255 Asp Val Phe Glu Gln Val Trp Arg Glu Tyr Pro Leu Arg Ala Gly Ala 260 265 270 Asn Pro Lys Lys Ser Ala Phe Ser Ala Trp Lys Ala Arg Leu Arg Glu 275 280 285 Gly Val Pro Pro Glu Thr Met Leu Asp Gly Val Arg Arg Tyr Ala Arg 290 295 300 Tyr Leu Ala Ala Thr Gly Lys Ala Gly Thr Glu Phe Val Gln Arg Ala 305 310 315 320 Thr Thr Phe Phe Gly Pro Asp Arg Asn Phe Glu Asn Pro Trp Leu Leu 325 330 335 Pro Val Ser Gly Thr Asn Asn Gln Arg Cys Val Asn His Ile Ser Glu 340 345 350 Pro Asp Thr Glu Ile Pro Pro Gly Phe Arg Gly * 355 360 <210> 430 <211> 249 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9901..10647) <400> 430 Met Lys Asn Ile Ala Ala Ala Gly Val Leu Glu Arg Ile Arg Arg Leu 1 5 10 15 Ala Pro Gln Ala Ser Val Pro Pro Tyr Arg Thr Val Glu Glu Trp Arg 20 25 30 Glu Trp Gln Leu Ala Glu Gly Arg Lys Arg Ser Glu Glu Ile Asn Arg 35 40 45 Gln Asn His Gln Leu Arg Val Glu Lys Ile Leu Asn Arg Ser Gly Ile 50 55 60 Gln Pro Leu His Ser Lys Cys Ser Phe Ala Asn Tyr Gln Val Gln Asn 65 70 75 80 Asp Gly Gln Lys Tyr Ala Leu Ser Gln Ala Lys Ser Ile Ala Asp Glu 85 90 95 Leu Met Thr Gly Cys Thr Asn Phe Val Phe Ser Gly Lys Thr Gly Thr 100 105 110 Gly Lys Asn His Leu Ala Ala Ala Met Gly Asn Arg Leu Met Ala Lys 115 120 125 Gly Arg Ser Val Ile Ile Val Thr Val Ser Asp Val Met Ser Val Leu 130 135 140 His Asp Ser Tyr Asp Asn Gly Lys Ser Gly Glu Lys Phe Leu Gln Glu 145 150 155 160 Leu Cys Ser Val Asp Leu Leu Val Leu Asp Glu Ile Gly Val Gln Arg 165 170 175 Glu Thr Lys Asn Glu Gln Val Val Leu His Gln Ile Ile Asp Arg Arg 180 185 190 Thr Ala Ser Leu Cys Ser Val Gly Met Leu Thr Asn Leu Asn His Ala 195 200 205 Ala Met Ser Thr Leu Leu Gly Glu Arg Ile Met Asp Arg Met Thr Met 210 215 220 Asn Gly Gly Arg Trp Val Thr Phe Asn Trp Asp Ser Trp Arg Pro Asn 225 230 235 240 Val Ser Asn Met Arg Val Val Lys * 245 <210> 431 <211> 257 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10669..11439) <400> 431 Met Glu Thr Val Ser Asp Ala Leu Lys Ala Leu Lys Lys Ala Ser Ser 1 5 10 15 His Val Val Ala Ala Arg Leu Gly Ile Ser Arg Glu Glu Ala Val Asn 20 25 30 Glu Leu Trp Glu Leu Lys Ile Asn Gly Val Val Asp Lys Thr Gly His 35 40 45 Thr Trp Phe Leu Ala Gly Glu Gly Glu Ser Arg Val Thr Glu Glu Arg 50 55 60 Pro Val Lys Ser Glu Ala Gln Asp Met Leu Thr Gly Glu Val Glu Gln 65 70 75 80 Lys Val Thr Ala Asp Met Met Ile Glu Phe Ile Gly Gln Asp Gly Ala 85 90 95 Lys Thr Cys Glu Glu Leu Ala Gly Lys Phe Gly Val Ser Thr Arg Lys 100 105 110 Val Ala Ser Thr Leu Ala Val Val Thr Ala Thr Gly Arg Leu Ala Arg 115 120 125 Val Asn Gln Asn Gly Lys Phe Arg Tyr Cys Met Pro Gly Asp Asn Leu 130 135 140 Pro Ala Glu Pro Lys Ala Ala Leu Val Thr Glu Ser Asp Gly Lys Ala 145 150 155 160 Phe Pro Gln Pro Ala Gly Ala Ala Leu Pro Val Arg Glu Ala Ala Thr 165 170 175 Gln Glu Glu Ile Lys Thr Glu Thr Val Ala Asp Ile Val Gln Pro Leu 180 185 190 Pro Ser Phe Thr Glu Thr Gln Ala Asp Glu Leu Ile Phe Pro Ser Leu 195 200 205 Arg Arg Ala Asn Leu Ala Leu Arg Arg Ala Lys Ser Asp Val Gln Lys 210 215 220 Trp Glu Arg Val Cys Ala Ala Leu Arg Glu Leu Asn Lys His Arg Asp 225 230 235 240 Ile Val Arg Gln Ile Thr Asp Ser Ser Arg Arg Val Val Ser Glu Lys 245 250 255 * <210> 432 <211> 138 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11455..11868) <400> 432 Met Ala Lys Val Phe Thr Gln Glu Glu Arg Glu Lys Ile Lys Gly Gln 1 5 10 15 Val Val Glu Leu Val Arg Arg Ser Gly Arg Glu Thr Leu Arg Gln Leu 20 25 30 Glu Ala Lys Thr Gly Ala Thr Arg Tyr Leu Met Ser Val Leu Ala Arg 35 40 45 Glu Leu Val Ala Ser Gly Asp Val Tyr Asn Ser Gly Tyr Gly Leu Phe 50 55 60 Pro Ser Glu Gln Ala Arg Lys Asp Trp Gln Asn Ala Arg Lys Lys Leu 65 70 75 80 Ser Arg Ala Lys Leu Lys Lys Pro Val Val Val Asp Pro Asp Leu Ile 85 90 95 Trp Ser Leu Pro Asp Gly Glu Ile Arg Arg Tyr Asp Arg Gln Leu Asn 100 105 110 Ile Ile Cys Ser Glu Cys Arg Asn Ser Glu Val Met Gln Arg Val Leu 115 120 125 Ile Phe Tyr Thr Gly Val Met Met Glu * 130 135 <210> 433 <211> 258 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12220..12993) <400> 433 Met Thr Lys His Met Asp Ile His Cys Gln Thr Arg Ile Phe Asn Ser 1 5 10 15 Ile Asn His Asp Thr Lys Tyr Lys Ile Cys Ile Phe Thr Pro Lys Asn 20 25 30 Ile Lys Lys Asn Asn Ala Thr Leu Tyr Ile Leu Asp Gly Asn Ser Ala 35 40 45 Asn Asn Tyr Ile Ser Asp Ile Leu Pro Val Ile Asp Ala Leu Pro Asn 50 55 60 Pro Pro Val Leu Val Thr Leu Gly Tyr Glu Ser Trp Asn Asn Leu Ser 65 70 75 80 Ile His Arg Arg Ala Tyr Asp Tyr Thr Pro Asp Gly Glu Asn Ala Ile 85 90 95 Val Asp Asn Ser Lys Pro Ala Trp Ile Tyr Phe Thr Gly Gly Gly Ser 100 105 110 Gln Ser Phe Arg Glu Leu Leu Leu Thr Gln Ile Met Pro Trp Val Ser 115 120 125 Thr Ile Ala Pro Asn Ser Ser Arg Ile Gly Ile Trp Gly His Ser Leu 130 135 140 Gly Ala Ile Phe Val Leu Asp Cys Leu Lys Asn Asn Ser Cys Phe Asn 145 150 155 160 Tyr Tyr Tyr Ile Ser Ala Pro Ser Leu Leu Trp Gln Asn Glu Arg Ile 165 170 175 Ile Lys Ile Ile Lys Asp Asp Ile Ser Glu Ser Lys His Thr Lys Ser 180 185 190 Ile Cys Leu Leu Asn Gly Asn Leu Ser Leu Asp Tyr Ser Ala Ser Leu 195 200 205 Tyr Pro Glu Ala Ile Lys Ala Glu Ser Val Leu Arg Asn Ile Leu Thr 210 215 220 Glu Lys Tyr Ser Asn Phe Ser Ile Val Gln Phe Pro Glu Leu Asn His 225 230 235 240 Gln Glu Thr Phe Ser Ala Ala Leu Trp Asn Ser Ile Ile His Phe Ser 245 250 255 Ile * <210> 434 <211> 54 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13035..13196) <400> 434 Met Ser Leu Ile Lys Asn Leu Leu Cys Val Phe Ser Tyr Phe Ile Tyr 1 5 10 15 Leu His Tyr Asp Leu Arg Leu Ile Tyr Val Ile Ser Lys Gly Thr Ser 20 25 30 Leu Leu Phe Tyr Leu Ser Ile His Leu Ile Leu Ile Ile Val Tyr Ile 35 40 45 Ala Cys Leu Gly Asn * 50 <210> 435 <211> 46 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13359..13496) <400> 435 Met Leu Thr Gly Ala Phe Leu Tyr Leu Pro Leu Val Phe Met Pro Glu 1 5 10 15 Ala Asp Ser Leu Lys His Pro Gln Leu Phe Tyr Leu Thr Ser His Tyr 20 25 30 Leu Ala Asn Met Lys Ser Val Arg Lys Thr Asp Val Pro * 35 40 45 <210> 436 <211> 71 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13541..13753) <400> 436 Met Asn Gly Lys Ser Arg Leu Ala Ser Tyr Val Pro Lys Gly Lys Glu 1 5 10 15 Lys Gln Ala Met Lys Gln Gln Lys Ala Met Leu Ile Ala Leu Ile Val 20 25 30 Ile Cys Leu Thr Val Ile Val Thr Ala Leu Val Thr Arg Lys Asp Leu 35 40 45 Cys Glu Val Arg Val Arg Thr Gly Gln Thr Glu Val Ala Val Phe Thr 50 55 60 Ala Tyr Glu Pro Glu Glu * 65 70 <210> 437 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13921..14199) <400> 437 Met Ala His Asp Thr Lys Leu Tyr Asn Ser Asp Asp Ser Ala Val Phe 1 5 10 15 Ala Ser Arg Arg Gly Arg Cys Phe His Ala Phe Lys Ser Asp Trp Tyr 20 25 30 Gln His Pro Pro Cys Thr Glu Glu Gln Ala Glu Trp Leu Ile Gln Cys 35 40 45 Tyr Arg Arg Arg Gly Cys Glu Val Lys Lys Ala Leu Ser Leu Asp Tyr 50 55 60 Arg His Trp Ile Ile Ser Val Arg Leu Pro Tyr Ser Glu Arg Pro Pro 65 70 75 80 Arg Pro Ser Arg Thr Phe Gln Gln Arg Ile Trp Arg * 85 90 <210> 438 <211> 326 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14273..15250) <400> 438 Met Ser Ala Phe His Asn Gly Arg Ile Leu Val Glu Pro Glu Pro Lys 1 5 10 15 Ser Met Arg Ala Leu Pro Ser Gly Val Val Pro Ala Val His Gln Pro 20 25 30 Leu Ala Glu Asp Lys Ser Leu Leu Pro Phe Phe Ser Asp Glu Arg Val 35 40 45 Ile Arg Ala Ala Gly Gly Ala Gly Ala Leu Ser Asp Trp Leu Leu Arg 50 55 60 His Val Lys Ser Cys Gln Trp Pro His Gly Asp Tyr His His Ser Glu 65 70 75 80 Thr Val Ile His Arg Tyr Gly Thr Gly Ala Met Val Leu Cys Trp His 85 90 95 Cys Asp Asn Gln Leu Arg Asp Gln Thr Ser Glu Ser Leu Glu Gln Leu 100 105 110 Ala Gln Gln Asn Leu Ala Ala Trp Met Ile Asp Val Ile Arg His Ala 115 120 125 Met Asn Gly Ile Gln Glu Arg Glu Leu Ser Leu Ala Glu Leu Ser Trp 130 135 140 Trp Ala Val Cys Asn Gln Val Val Asp Ala Leu Pro Glu Ala Val Ser 145 150 155 160 Arg Arg Ser Leu Gly Leu Pro Ala Glu Lys Ile Arg Ser Val Tyr Arg 165 170 175 Glu Ser Asp Ile Ile Pro Gly Glu Gln Thr Ala Thr Ser Ile Leu Lys 180 185 190 Gln Arg Thr Lys Asn Ile Ala Leu Pro Pro His Thr His Gln Gln Gln 195 200 205 Asn Pro Pro Gln Glu Lys Thr Val Val Ser Ile Ala Val Asp Pro Glu 210 215 220 Ser Pro Lys Ser Phe Met Lys Arg Pro Lys Arg Arg Arg Trp Val Asn 225 230 235 240 Glu Lys Tyr Thr Arg Trp Val Lys Thr Gln Pro Cys Ala Cys Cys Gly 245 250 255 Lys Pro Ala Asp Asp Pro His His Leu Ile Gly His Gly Gln Gly Gly 260 265 270 Met Gly Thr Lys Ser His Asp Ile Phe Thr Leu Pro Leu Cys Arg Glu 275 280 285 His His Asn Glu Leu His Ala Asp Pro Leu Ala Phe Glu Glu Lys His 290 295 300 Gly Ser Gln Val Asp Leu Ile Phe Arg Phe Leu Asp His Ala Phe Ala 305 310 315 320 Thr Gly Val Leu Gly * 325 <210> 439 <211> 124 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15263..15634) <400> 439 Met Arg Ile Glu Phe Val Leu Pro Tyr Pro Pro Thr Val Asn Thr Tyr 1 5 10 15 Trp Arg Arg Arg Gly Ser Thr Tyr Phe Val Ser Lys Ala Gly Glu Arg 20 25 30 Tyr Arg Arg Ala Val Ala Leu Ile Val Arg Gln Gln Arg Leu Lys Leu 35 40 45 Ser Leu Ser Gly Arg Leu Ala Ile Lys Ile Ile Ala Glu Pro Pro Asp 50 55 60 Lys Arg Arg Arg Asp Leu Asp Asn Ile Leu Lys Ala Pro Leu Asp Ala 65 70 75 80 Leu Thr His Ala Glu Val Leu Ile Asp Asp Glu Gln Phe Asp Glu Ile 85 90 95 Asn Ile Val Arg Gly Gln Pro Val Pro Gly Gly Arg Leu Gly Val Lys 100 105 110 Ile Tyr Glu Ile Arg Gly Gly Asn Asp Gly Ala * 115 120 <210> 440 <211> 124 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15624..15995) <400> 440 Met Ala Arg Asp Ile Gln Met Val Leu Glu Arg Trp Gly Ala Trp Ala 1 5 10 15 Ala Asn Asn His Glu Asp Val Thr Trp Pro Ser Ile Ala Ala Gly Phe 20 25 30 Lys Gly Leu Ile Pro Thr Lys Val Lys Ser Arg Pro Lys Cys Ser Asp 35 40 45 Asp Asp Ala Met Ile Ile Cys Gly Cys Met Ala Arg Leu Asn Lys Asn 50 55 60 Asn Gln Tyr Leu His Asp Leu Leu Val Asp Tyr Tyr Val Gly Gly Met 65 70 75 80 Thr Phe Met Ala Leu Ala Arg Lys His Arg Cys Ser Asp Gly Leu Ile 85 90 95 Gly Lys Arg Leu Tyr Lys Ala Glu Gly Ile Ile Glu Gly Met Leu Met 100 105 110 Ala Leu Asn Val Arg Leu Asp Met Asp Met Arg * 115 120 <210> 441 <211> 273 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16147..16965) <400> 441 Met Trp Ile Val Leu Val Leu Ser Leu Ser Thr Leu Ser Trp His Lys 1 5 10 15 Val Val Ala Phe Ser Leu Leu Thr Val Ser Val Val Leu Ala Val Leu 20 25 30 Asn Asp Ile Ile Asp Trp Ser Val Leu Phe Phe Val Ala Thr Ile Val 35 40 45 Phe Phe Ile Ile Leu Lys Phe Asn Trp Lys Tyr Asn Ala Trp Ala Lys 50 55 60 Ser Ile Tyr Glu Val Gly Ile Val Leu Ser Ala Ile Ala Leu Phe Phe 65 70 75 80 His Leu Trp Pro Gly Phe His Asn Pro Val Val Leu Asn Ser Val Thr 85 90 95 Val Gly Pro Gln Ser Thr Pro Tyr Thr Met Tyr Phe Asn Phe Asp Lys 100 105 110 Ala Leu Val Pro Phe Leu Leu Val Leu Cys Thr Ser Ser Leu Phe Lys 115 120 125 Lys Glu Val Lys Ser Glu Val Ser Leu Trp Lys Trp Gly Ala Leu Ser 130 135 140 Leu Ser Val Pro Leu Ile Leu Phe Leu Ala Val Phe Phe Gly Gly Leu 145 150 155 160 Lys Pro Glu Ile His Phe Pro Glu Trp Leu Pro Glu Phe Ile Leu Ala 165 170 175 Asn Leu Phe Phe Val Ser Leu Ala Glu Glu Ser Leu Phe Arg Gly Tyr 180 185 190 Ile Gln Ser Arg Leu Ser Glu Val Thr Ser Pro Leu Val Ala Leu Ile 195 200 205 Val Ala Ala Leu Leu Phe Gly Phe Tyr His Tyr Ser Gly Gly Ala Leu 210 215 220 Leu Val Leu Phe Ala Thr Leu Ser Gly Val Val Tyr Gly Leu Ser Trp 225 230 235 240 Met Trp Ser Gly Arg Leu Trp Val Ala Thr Leu Phe His Phe Gly Leu 245 250 255 Asn Leu Cys His Leu Leu Phe Phe Thr Tyr Pro Phe Leu Lys His Asn 260 265 270 * <210> 442 <211> 80 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17252..17491) <400> 442 Met Leu Lys Gln Gln Asp Met Thr Glu Thr Ala Arg Val Val Phe Asp 1 5 10 15 Glu Leu Ser Val Thr Glu Pro Ala Thr Val Gly Glu Ile Ala Gln Asn 20 25 30 Thr Tyr Leu Ser Arg Glu Arg Cys Gln Leu Ile Leu Thr Gln Leu Val 35 40 45 Met Arg Val Trp Gln Thr Ile Ser Ser Val Val Thr Asp Ala Phe Ser 50 55 60 Pro Glu Gly Phe Phe Ile Cys Gly Lys Trp Ala Ala Gly Gly Cys * 65 70 75 <210> 443 <211> 196 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17712..18299) <400> 443 Met His Tyr Gly Lys Val Lys Ile Phe Asp Ile Asn His Ser Ile Val 1 5 10 15 Ser Gln Tyr Leu Glu Ile Gln His Lys Leu Thr Arg Thr His Leu Thr 20 25 30 Asp Val Pro Leu Tyr Leu Ser Leu Glu Pro Asn Asn Pro Ala Leu Ala 35 40 45 Glu Ala Leu Ile Thr Ser Gln Arg Phe Ser Gly Asp Thr Thr Asp Met 50 55 60 Phe Leu Met Met Ala Cys Leu Ser Leu Phe Glu Ser Asp Glu Arg Ile 65 70 75 80 Leu Leu Phe Leu Ser Gly Cys Leu Ser Ser Ile Ser Ala Lys Val Arg 85 90 95 Ala Ile Ile Gln Thr Asp Ile Ser Ala Ser Trp Thr Leu Gly Ala Ile 100 105 110 Ala Leu Arg Leu His Met Ser Glu Ser Leu Leu Lys Ile Lys Leu Lys 115 120 125 Asn Glu Gly His Met Phe Ser Arg Leu Leu Leu Glu Glu Arg Met Arg 130 135 140 Val Ala Val Asn Met Leu Cys Ser Arg His Gly Tyr Gly Gln Ala Val 145 150 155 160 Ala Glu Lys Cys Gly Tyr Ser Ser Trp Ser Tyr Phe Ile Ser Val Phe 165 170 175 His Arg Tyr Tyr Gly Phe Pro Pro Asp Arg Tyr Val Ser Arg Gln Gly 180 185 190 Leu Asp Tyr * 195 <210> 444 <211> 617 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19067..20917) <400> 444 Met Ala Phe Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Glu Lys Leu Thr His Lys Leu Lys Glu Gly Trp Gln Pro Tyr 20 25 30 Gly Gly Pro Val Ala Ile Thr Pro Tyr Thr Leu Met Gln Ala Val Ala 35 40 45 Ile Glu Gly Asp Pro Gln Val Gly Pro Ser Ser Lys Pro Asp Trp Phe 50 55 60 Tyr Val Val Val Leu Ala Gly Gln Ser Asn Gly Met Ala Tyr Gly Glu 65 70 75 80 Gly Leu Pro Leu Pro Asp Ser Tyr Asp Ala Pro Asp Pro Arg Ile Lys 85 90 95 Gln Leu Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Glu Ser Cys Thr 100 105 110 Tyr Asn Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln Asp 115 120 125 Met Ser Thr Leu Asn His Pro Lys Ala Asp Leu Ser Lys Gly Gln Tyr 130 135 140 Gly Cys Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro Tyr 145 150 155 160 Ile Pro Asn Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly Gly 165 170 175 Ser Ala Phe Thr Gln Gly Ala Glu Gly Thr Phe Ser Ala Asp Thr Gly 180 185 190 Ala Ser Gln Asp Ser Ala Arg Trp Gly Val Gly Lys Pro Leu Tyr Gln 195 200 205 Asp Leu Ile Ala Arg Thr Lys Ala Ala Leu Gln Lys Asn Pro Lys Asn 210 215 220 Val Leu Leu Ala Val Cys Trp Met Gln Gly Glu Phe Asp Met Ser Ala 225 230 235 240 Ala Thr His Ala Gln Gln Pro Ala Leu Phe Thr Ala Met Leu Thr Gln 245 250 255 Phe Arg Ala Asp Leu Ser Val Phe Asn Ala Gln Cys His Gly Gly Ser 260 265 270 Ala Ala Asp Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Tyr Trp Lys 275 280 285 Asn Thr Tyr Ala Thr Gln Tyr Asp Thr Val Tyr Gly Gly Tyr Lys Asn 290 295 300 Arg Glu Ser Glu Gly Val Tyr Phe Val Pro Phe Met Thr Asp Gly Asn 305 310 315 320 Gly Val Asn Thr Ala Thr Asn Ala Pro Ala Glu Asp Pro Asp Ile Pro 325 330 335 Ala Ser Gly Tyr Tyr Gly Ala Ala Ser Arg Thr Asn Gly Asn Gln Val 340 345 350 Ser Ser Asn Arg Pro Thr His Phe Ser Ser Trp Ala Arg Arg Ser Ile 355 360 365 Ile Pro Asp Arg Leu Ala Thr Ala Ile Leu Asn Ala Ala Gly Arg Thr 370 375 380 Ser Ala Phe Ile Ser Gly Lys Ala Pro Glu Ile Lys Pro Ser Pro Gly 385 390 395 400 Gly Asn Thr Pro Ser Gly Pro Ser Ala Asp Thr Ser Val Arg Thr Ile 405 410 415 Ser Leu Leu Pro Ala Ala Gly Glu Ala Ala Ala Gln Gly Trp Ser Ile 420 425 430 Lys Asp Gly Gly Ile Gln Leu Ser Asp Gly Val Phe Lys Ile Thr Arg 435 440 445 Gln Ser Asn Lys Thr Trp Ser Leu Thr His Pro Val Asp Asp Ala Ile 450 455 460 Thr Leu Leu Thr Gln Gly Gly Arg Leu Asn Cys Lys Phe Arg Leu Ser 465 470 475 480 Gly Ala Leu Thr Asn Asn Gln Phe Gly Leu Gly Ile Tyr Leu Tyr Thr 485 490 495 Asp Ala Pro Val Pro Asp Gly Val Ala Met Thr Gly Thr Gly Asn Pro 500 505 510 Phe Leu Met Ser Tyr Phe Thr Gln Thr Thr Asp Gly Arg Val Asn Leu 515 520 525 Met His His Arg Lys Ala Gly Asn Thr Lys Leu Gly Glu Phe Gly Asp 530 535 540 Tyr Gly Asn Asp Trp Gln Thr Leu Glu Leu Val Phe Thr Ala Gly Ser 545 550 555 560 Ala Thr Val Thr Pro Lys Leu Asn Gly Val Ala Gly Pro Ala Phe Gln 565 570 575 Val Ile Lys Asp Ser Leu Thr Leu Gly Leu Asn Ala Leu Thr Leu Thr 580 585 590 Asp Val Thr Lys Asn Ala Ala Tyr Gly Val Glu Ile Glu Ser Leu Val 595 600 605 Leu Glu Ile Asn Ala Pro Ala Ala * 610 615 <210> 445 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21093..21419) <400> 445 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 446 <211> 218 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21416..22069) <400> 446 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Trp Ala Arg Arg Pro Ser Gly Thr Ile 100 105 110 His His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu 115 120 125 Arg Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp 130 135 140 Ser Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala 145 150 155 160 Glu Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu 165 170 175 Ala Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly 180 185 190 Arg Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala 195 200 205 Ser Ile Gly Asn Asp Asp Leu Ala Ala * 210 215 <210> 447 <211> 105 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22274..22588) <400> 447 Met Leu His Asp His Val Ala Glu Cys Leu Glu Lys Lys Gly Leu Tyr 1 5 10 15 Arg Arg Ala Ala Glu Arg Trp Ala Lys Val Met Val Gln Leu Ser Asp 20 25 30 Asp Gln Lys Arg Lys Val Ala Ala Gln Lys Arg Ala Glu Cys Leu Arg 35 40 45 Lys Ala Arg Arg Thr Pro Val Ser Pro Val Asn Leu Thr Glu Ile Lys 50 55 60 Gln Ala Val Asn Arg Leu His Ser Glu Leu Gly Met Gly Phe Glu Glu 65 70 75 80 Arg Arg Val Phe Arg Arg Tyr Lys Gly Thr Gly Glu Gln Asn Thr Ser 85 90 95 Gly Asn Ala Arg Ser Lys Lys Cys * 100 <210> 448 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23116..23301) <400> 448 Met Arg Glu Leu Lys Met Lys Leu Cys Val Leu Met Leu Pro Leu Val 1 5 10 15 Val Ser Ala Cys Gly Ser Thr Pro Pro Ala Pro Val Pro Cys Val Lys 20 25 30 Pro Pro Ala Pro Pro Ala Trp Ile Met Gln Pro Ala Pro Asp Trp Gln 35 40 45 Thr Pro Leu Asn Gly Ile Ile Ser Ser Ser Glu Asn Gly * 50 55 60 <210> 449 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23054..23521) <400> 449 Met Asn Arg Val Leu Cys Val Val Ile Ile Val Leu Leu Val Ala Cys 1 5 10 15 Gly Ala Leu Ser Leu Gly Leu Asn His Tyr Arg Asp His Ala Ile Ile 20 25 30 Tyr Lys Glu Gln Arg Asp Lys Lys Ala Ser Glu Leu Glu Leu Ala Asn 35 40 45 Ala Thr Ile Thr Asp Met Gln Ile Arg Gln Arg Asp Val Ala Ala Leu 50 55 60 Asp Ala Arg Tyr Ser Arg Glu Leu Ala Asp Ala Arg Ala Glu Asn Glu 65 70 75 80 Thr Leu Arg Ala Asp Val Ala Ala Gly Arg Lys Arg Leu Arg Ile Asn 85 90 95 Ala Thr Cys Ser Gly Thr Val Arg Glu Ala Thr Gly Thr Ser Gly Val 100 105 110 Asp Asn Ala Thr Gly Pro Arg Leu Ala Asp Thr Ala Glu Arg Asp Tyr 115 120 125 Phe Ile Leu Arg Glu Arg Leu Met Ala Met Gln Lys Gln Leu Glu Gly 130 135 140 Ala Gln Glu Tyr Ile Arg Thr Gln Cys Ile Pro * 145 150 155 <210> 450 <211> 38 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23523..23636) <400> 450 Met Lys Gly Ile Glu Val Glu Thr Pro Ala Ser Leu Asp Leu Thr Arg 1 5 10 15 Ala Ala Ala Phe Ala Ile Arg Ile Val Ala Ile Ala Val Leu Val Trp 20 25 30 Ala Ile Arg Trp Trp * 35 <210> 451 <211> 56 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23841..24008) <400> 451 Met Gln Ala Ile Glu Lys Val Pro Val Arg Arg Phe Ala Gly Gly Leu 1 5 10 15 Arg Thr Val Ala Glu Thr Ala Val Ser Val Gln Ile Ile Ala Thr Val 20 25 30 Arg Ser His Gly Val Thr Arg Arg Ala Arg Trp Arg Ala Gly Thr Ser 35 40 45 Thr Asp Ser Arg Ile Phe Ser * 50 55 <210> 452 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23857..24390) <400> 452 Met Asn Glu Lys Ile Lys Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Gly Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Ile Leu Val Asp Gly Lys Pro Val Ile 50 55 60 Pro Gly Met Lys Leu Ser Lys Glu Lys Cys Asp Arg Val Asn Ala Ile 65 70 75 80 Glu Arg Asp Lys Ala Leu Ala Trp Val Glu Lys Asn Ile Arg Val Pro 85 90 95 Leu Thr Glu Pro Gln Lys Ala Gly Ile Ala Ser Phe Cys Pro Tyr Asn 100 105 110 Ile Gly Pro Gly Lys Cys Phe Pro Ser Thr Phe Tyr Lys Arg Ile Asn 115 120 125 Ala Gly Asp Arg Lys Gly Ala Cys Glu Ala Ile Arg Trp Trp Ile Lys 130 135 140 Asp Gly Gly Arg Asp Cys Arg Ile Arg Ser Asn Asn Cys Tyr Gly Gln 145 150 155 160 Val Ser Arg Arg Asp Gln Glu Ser Ala Leu Ala Cys Trp Asp Ile Asp 165 170 175 Arg * <210> 453 <211> 79 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24586..24822) <400> 453 Met Ala Asp Asn Asn Glu Ala Thr Ser Ser Ile Leu Ala Asp Pro Tyr 1 5 10 15 Gly Lys Ile Ser His Lys Thr Leu Asp Ile Ile Thr Thr Thr Leu Thr 20 25 30 Pro Leu Met Leu Gln Arg Leu Lys His Asn Ile Asn Ala Trp Val Asn 35 40 45 Glu Glu Leu Ser Pro Pro Cys Leu Trp Asp Ser Arg Tyr Ala Cys Gln 50 55 60 Gln Lys Met Arg Ile Phe Asn Leu Leu Ser Pro Lys Leu Arg * 65 70 75 <210> 454 <211> 65 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24423..24617) <400> 454 Met Leu Leu Val Ala Ser Leu Leu Ser Ala Ile Arg Arg Ser Asn Ser 1 5 10 15 Asp Leu Thr Phe Ser Val Ile Ser Cys Lys Asn Leu Leu Arg Lys Leu 20 25 30 Ser Leu Leu Phe Ile Tyr Met Ala Ser Phe Val Val Ile Cys Cys Val 35 40 45 Ser Arg Asp Met Phe Met Arg Ala Thr Met Ser Val Gly Leu Tyr Thr 50 55 60 * <210> 455 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24771..25115) <400> 455 Met Ser Ala Lys Asn Ala Asn Phe Gln Leu Thr Ile Thr Lys Ala Gln 1 5 10 15 Val Ala Ile Lys Ser Cys Pro Ser Trp His Thr Gly Phe Gln Trp Asn 20 25 30 His Asn Asp Gln Leu Leu His Ser Cys Ile Pro Asp Ser Pro Thr Thr 35 40 45 Gln Ile Phe Ser Ile Cys Cys Tyr Leu Lys Arg Lys Arg Thr Asn Ala 50 55 60 Arg Val Phe His His Val Leu Leu Leu Ile Ala Cys Asp Leu Phe Leu 65 70 75 80 Pro His Gly Thr Phe Phe Gln Leu Glu Ile Phe Ile Leu Gln Pro Val 85 90 95 Arg Ile Val Tyr Ser Ser Thr Thr Leu Pro Ala Pro Pro Tyr Asp Gly 100 105 110 Pro Leu * <210> 456 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25078..25284) <400> 456 Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser Ala Val Gly 1 5 10 15 Thr Glu Tyr Trp Leu Leu Gln Leu Leu Asp Lys Val Ser Pro Ser Gln 20 25 30 Trp Val Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly Leu Leu Thr 35 40 45 Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Arg Glu Asp Arg Arg Lys Val 50 55 60 Ala Arg Gly Glu * 65 <210> 457 <211> 92 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26035..26310) <400> 457 Val Ala Thr Gln Thr Glu Val Ala Arg His Leu Ser Leu Thr Asp Arg 1 5 10 15 Gln Leu Arg Arg Leu Gln Lys Leu Pro Gly Ala Pro Ile Ser Asn Lys 20 25 30 Arg Gly Gln Leu Asp Leu Asp Ala Trp Arg Asp Phe Tyr Ile Ser Tyr 35 40 45 Leu Arg Arg Ser Lys Asn Asp Val Pro Asp Gly Asp Ser Glu Asp Asp 50 55 60 Tyr Glu Glu Lys Leu Leu Ile Ala Arg Trp Glu Leu Thr Ala Glu Gln 65 70 75 80 Ala Val Thr Gln Gln Leu Lys Lys Arg Thr Ala * 85 90 <210> 458 <211> 127 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26386..26766) <400> 458 Met Gln Lys Asn Val Thr Pro Gly Arg Arg Lys Gly Cys Pro Asn Tyr 1 5 10 15 Pro Pro Glu Phe Lys Gln Gln Leu Val Ala Ala Ser Cys Glu Pro Gly 20 25 30 Ile Ser Ile Ser Lys Leu Ala Leu Glu Asn Gly Ile Asn Ala Asn Leu 35 40 45 Leu Phe Lys Trp Arg Gln Gln Trp Arg Glu Gly Lys Leu Leu Leu Pro 50 55 60 Ser Ser Glu Ser Pro Gln Leu Leu Pro Val Thr Leu Asp Ala Ala Ala 65 70 75 80 Glu Gln Pro Glu Ser Leu Ala Glu Asp Pro Glu Thr Leu Ser Ile Ser 85 90 95 Cys Glu Val Thr Phe Arg His Gly Thr Leu Arg Phe Asn Gly Asn Val 100 105 110 Ser Glu Lys Leu Leu Thr Leu Leu Ile Gln Glu Leu Lys Arg * 115 120 125 <210> 459 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26763..27110) <400> 459 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Asp Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 460 <211> 513 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27160..28698) <400> 460 Met Asn Asp Ile Ser Ser Asp Asp Ile Phe Leu Leu Lys Gln Arg Leu 1 5 10 15 Ala Glu Gln Glu Ala Leu Ile His Ala Leu Gln Glu Lys Leu Ser Asn 20 25 30 Arg Glu Arg Glu Ile Asp His Leu Gln Ala Gln Leu Asp Lys Leu Arg 35 40 45 Arg Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala 50 55 60 Gln Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu 65 70 75 80 Thr Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr 85 90 95 Arg Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg 100 105 110 Leu Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser 115 120 125 Tyr Leu Gly Glu Asp Thr Ala Glu Gln Leu Glu Leu Met Arg Ser Ala 130 135 140 Phe Arg Val Ile Arg Thr Val Arg Glu Lys His Ala Cys Thr Gln Cys 145 150 155 160 Asp Ala Ile Val Gln Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly 165 170 175 Ile Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Ser Lys Tyr Ala 180 185 190 Glu His Thr Pro Leu Tyr Arg Gln Ser Glu Ile Tyr Gly Arg Gln Gly 195 200 205 Val Glu Leu Arg Arg Ser Leu Leu Ser Gly Trp Val Asp Ala Cys Cys 210 215 220 Arg Leu Leu Ser Pro Leu Glu Glu Ala Leu His Gly Tyr Val Met Thr 225 230 235 240 Asp Gly Lys Leu His Ala Asp Asp Thr Pro Val Gln Val Leu Leu Pro 245 250 255 Gly Asn Lys Lys Thr Lys Thr Gly Arg Leu Trp Ala Tyr Val Arg Asp 260 265 270 Asp Arg Asn Ala Gly Ser Ala Leu Ala Pro Ala Val Trp Phe Ala Tyr 275 280 285 Ser Pro Asp Arg Lys Gly Ile His Pro Gln Thr His Leu Ala Cys Phe 290 295 300 Ser Gly Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr 305 310 315 320 Arg Asn Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg 325 330 335 Lys Ile His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu 340 345 350 Ala Leu Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg 355 360 365 Gly Met Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys 370 375 380 Pro Leu Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr 385 390 395 400 Leu Ser Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn 405 410 415 Gln Trp Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile 420 425 430 Asp Asn Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg 435 440 445 Lys Asn Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala 450 455 460 Leu Leu Tyr Ser Leu Ile Gly Thr Cys Lys Leu Asn Asp Val Asp Pro 465 470 475 480 Glu Ser Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val 485 490 495 Asn Arg Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu 500 505 510 * <210> 461 <211> 81 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28748..28990) <400> 461 Val Ser Lys Gly Lys Leu Ile Asp Thr Gly Phe Cys Ile Phe Ala Leu 1 5 10 15 Ser Lys Leu Ala Met Ala Leu Ser Ser Thr Leu Asp Ser Ile Pro Leu 20 25 30 Ser Met Gln Arg Gln Phe Pro Asp Leu Thr Pro Arg His Leu Asp His 35 40 45 Leu Lys Thr Leu Ile Ala Lys Gly Ala Asn Gln Cys Ala Arg Ala Gly 50 55 60 Asp Lys Leu Pro Asp Leu Leu Asp Glu Tyr Ile Arg Ala Thr Thr Glu 65 70 75 80 * <210> 462 <211> 643 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28962..30890) <400> 462 Met Asn Ile Ser Glu Gln Gln Leu Asn Asn Met Met Ser Ala Val Thr 1 5 10 15 Thr Ala Leu Gln Pro Leu Ile Arg Ala Leu Pro Val Thr Pro Val Glu 20 25 30 Trp Ala Asp Gln Asn Tyr Tyr Leu Pro Lys Glu Ser Ser Tyr Gly Glu 35 40 45 Gly Glu Trp Lys Thr Leu Pro Phe Gln Ile Ala Ile Met Asn Ser Met 50 55 60 Gly Asn Asp Gln Ile Arg Thr Val Asn Leu Ile Lys Ser Ala Arg Val 65 70 75 80 Gly Tyr Thr Lys Met Leu Leu Gly Gly Gly Gly Tyr Phe Ile Glu His 85 90 95 Lys Ser Arg Asn Ser Leu Leu Phe Gln Pro Thr Asp Ser Ala Ala Glu 100 105 110 Asp Phe Met Lys Ser His Val Glu Ala Thr Ile Arg Asn Val Pro Cys 115 120 125 Leu Lys Asp Leu Ser Pro Trp Leu Gly Arg Lys His Arg Asp Asn Thr 130 135 140 Leu Thr Leu Lys Arg Phe Ser Ser Gly Val Gly Phe Trp Cys Leu Gly 145 150 155 160 Gly Ala Ala Ala Lys Asn Tyr Arg Glu Lys Ser Val Asp Val Val Cys 165 170 175 Tyr Asp Glu Leu Ser Ser Phe Glu Pro Asp Val Glu Lys Glu Gly Ser 180 185 190 Pro Thr Leu Leu Gly Asp Lys Arg Ile Glu Gly Ser Val Trp Pro Lys 195 200 205 Ser Ile Arg Gly Ser Thr Pro Lys Ile Lys Gly Thr Cys Gln Ile Glu 210 215 220 Lys Ala Ala Asn Glu Ser Ala His Phe Met Arg Phe Tyr Val Pro Cys 225 230 235 240 Pro His Cys Gly Glu Ala Gln Tyr Leu Lys Phe Gly Asp Glu Ser Thr 245 250 255 Pro Phe Gly Leu Lys Trp Glu Lys Asp Ser Pro Glu Ser Val Phe Tyr 260 265 270 Leu Cys Glu His His Gly Cys Val Ile His Gln Ser Glu Leu Asp Gln 275 280 285 Ser Asn Gly Arg Trp Ile Cys Glu Asn Thr Gly Met Trp Thr Arg Asp 290 295 300 Gly Leu Thr Phe Phe Ser Ala Arg Gly Asp Glu Ile Pro Pro Pro Arg 305 310 315 320 Ser Ile Met Phe His Ile Trp Thr Ala Tyr Ser Pro Phe Thr Thr Trp 325 330 335 Val Gln Ile Val Tyr Asp Trp Leu Asp Ala Leu Lys Asp Pro Asn Gly 340 345 350 Leu Lys Thr Phe Val Asn Thr Thr Leu Gly Glu Thr Trp Glu Glu Ala 355 360 365 Val Gly Glu Lys Leu Asp His Gln Val Leu Met Asp Lys Val Val Arg 370 375 380 Tyr Thr Ala Ala Val Pro Ala Arg Val Val Tyr Leu Thr Ala Gly Ile 385 390 395 400 Asp Ser Gln Arg Asn Arg Phe Glu Met Tyr Val Trp Gly Trp Ala Pro 405 410 415 Gly Glu Glu Ala Phe Leu Val Asp Lys Ile Ile Ile Met Gly Arg Pro 420 425 430 Asp Glu Glu Glu Thr Leu Leu Arg Val Asp Ala Ala Ile Asn Lys Lys 435 440 445 Tyr Arg His Ala Asp Gly Thr Glu Met Thr Ile Ser Arg Val Cys Trp 450 455 460 Asp Thr Gly Gly Ile Asp Gly Glu Ile Val Tyr Gln Arg Ser Lys Lys 465 470 475 480 His Gly Val Phe Arg Val Leu Pro Val Lys Gly Ala Ser Val Tyr Gly 485 490 495 Lys Pro Val Ile Thr Met Pro Lys Thr Arg Asn Gln Arg Gly Val Tyr 500 505 510 Leu Cys Glu Val Gly Thr Asp Thr Ala Lys Glu Ile Leu Tyr Ala Arg 515 520 525 Met Lys Ala Asp Pro Ser Pro Ala Asp Glu Ala Thr Ser Tyr Ala Ile 530 535 540 Arg Phe Pro Asp Asp Pro Glu Ile Phe Ser Gln Thr Glu Ala Gln Gln 545 550 555 560 Leu Val Ala Glu Glu Leu Val Glu Lys Trp Glu Lys Gly Lys Met Arg 565 570 575 Leu Leu Trp Asp Asn Lys Lys Arg Arg Asn Glu Ala Leu Asp Cys Leu 580 585 590 Val Tyr Ala Tyr Ala Ala Leu Arg Val Ser Val Gln Arg Trp Gln Leu 595 600 605 Asp Leu Ala Val Leu Ala Lys Ser Arg Glu Glu Glu Thr Thr Arg Pro 610 615 620 Thr Leu Lys Glu Leu Ala Ala Lys Leu Ser Gly Gly Val Asn Gly Tyr 625 630 635 640 Ser Arg * <210> 463 <211> 531 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31077..32669) <400> 463 Met Lys Arg Thr Pro Val Leu Ile Asp Val Asn Gly Val Pro Leu Arg 1 5 10 15 Glu Ser Leu Ser Tyr Asn Gly Gly Gly Ala Gly Phe Gly Gly Gln Met 20 25 30 Ala Glu Trp Leu Pro Pro Ala Gln Ser Ala Asp Ala Ala Leu Leu Pro 35 40 45 Ala Leu Arg Leu Gly Asn Ala Arg Ala Asp Asp Leu Val Arg Asn Asn 50 55 60 Gly Ile Ala Ala Asn Ala Val Ala Leu His Lys Asp His Ile Val Gly 65 70 75 80 His Met Phe Leu Ile Ser Tyr Arg Pro Asn Trp Arg Trp Leu Gly Met 85 90 95 Arg Glu Thr Ala Ala Lys Ser Phe Val Asp Glu Val Glu Ala Ala Trp 100 105 110 Ser Glu Tyr Ala Glu Gly Met Ser Gly Glu Ile Asp Val Glu Gly Lys 115 120 125 Arg Thr Phe Thr Glu Phe Ile Arg Glu Gly Val Gly Val His Ala Phe 130 135 140 Asn Gly Glu Ile Phe Val Gln Pro Val Trp Asp Thr Glu Thr Thr Gln 145 150 155 160 Leu Phe Arg Thr Arg Phe Lys Ala Val Ser Pro Lys Arg Val Asp Thr 165 170 175 Pro Gly His Gly Met Gly Asn Arg Phe Leu Arg Ala Gly Val Glu Val 180 185 190 Asp Arg Tyr Gly Arg Ala Val Ala Tyr His Ile Cys Glu Asp Asp Phe 195 200 205 Pro Arg Ser Gly Ser Gly Arg Trp Glu Arg Ile Pro Arg Glu Leu Pro 210 215 220 Thr Gly Arg Pro Ala Met Leu His Ile Phe Glu Pro Val Glu Asp Gly 225 230 235 240 Gln Thr Arg Gly Ala Asn Gln Phe Tyr Ser Val Met Glu Arg Leu Lys 245 250 255 Met Leu Asp Ser Leu Gln Ala Thr Gln Leu Gln Ser Ala Ile Val Lys 260 265 270 Ala Met Tyr Ala Ala Thr Ile Glu Ser Asp Leu Asp Thr Glu Lys Ala 275 280 285 Phe Glu Tyr Ile Ala Gly Ala Pro Gln Gly Gln Lys Asp Asn Pro Leu 290 295 300 Ile Asn Ile Leu Glu Lys Phe Ser Ser Trp Tyr Asp Thr Asn Asn Val 305 310 315 320 Thr Leu Gly Gly Val Lys Ile Pro His Leu Phe Pro Gly Asp Asp Leu 325 330 335 Lys Leu Gln Thr Ala Gln Asp Ser Asp Asn Gly Phe Ser Ala Leu Glu 340 345 350 Gln Ala Leu Leu Arg Tyr Ile Ala Ala Gly Leu Gly Val Ser Tyr Glu 355 360 365 Gln Leu Ser Arg Asp Tyr Ser Lys Val Ser Tyr Ser Ser Ala Arg Ala 370 375 380 Ser Ala Asn Glu Ser Trp Arg Tyr Phe Met Gly Arg Arg Lys Phe Ile 385 390 395 400 Ala Ala Arg Leu Ala Thr Gln Met Phe Ser Tyr Trp Leu Glu Glu Ala 405 410 415 Leu Leu Arg Gly Ile Ile Arg Pro Pro Arg Ala Arg Phe Asp Phe Tyr 420 425 430 Gln Ala Arg Ser Ala Trp Ser Arg Ala Glu Trp Ile Gly Ala Gly Arg 435 440 445 Met Ala Ile Asp Gly Leu Lys Glu Val Gln Glu Ser Val Met Arg Ile 450 455 460 Glu Ala Gly Leu Ser Thr Tyr Glu Lys Glu Pro Ala Leu Met Gly Glu 465 470 475 480 Asp Tyr Gln Asp Ile Phe Arg Gln Gln Val Arg Glu Ser Ala Glu Arg 485 490 495 Gln Lys Ala Gly Leu Ser Arg Pro Val Trp Ile Ala Gln Ala Tyr Gln 500 505 510 Gln Gln Ile Ala Glu Ser Arg Arg Pro Glu Glu Glu Thr Thr Pro Arg 515 520 525 Glu Thr * 530 <210> 464 <211> 502 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32659..34164) <400> 464 Val Arg Arg Asn Leu Ser His Ile Ile Ala Ala Ala Phe Asn Glu Pro 1 5 10 15 Leu Leu Leu Glu Pro Ala Tyr Ala Arg Val Phe Phe Cys Ala Leu Gly 20 25 30 Arg Glu Met Gly Ala Ala Ser Leu Ser Val Pro Gln Gln Gln Val Gln 35 40 45 Leu Asp Ala Pro Gly Met Leu Ala Glu Thr Asp Glu Tyr Met Ala Gly 50 55 60 Gly Lys Arg Pro Ala Arg Val Tyr Arg Val Val Asn Gly Ile Ala Val 65 70 75 80 Leu Pro Val Thr Gly Thr Leu Val His Arg Leu Gly Gly Met Arg Pro 85 90 95 Phe Ser Gly Met Thr Gly Tyr Asp Gly Ile Val Ala Cys Leu Gln Gln 100 105 110 Ala Met Ala Asp Ser Gln Val Arg Gly Val Leu Leu Asp Ile Asp Ser 115 120 125 Pro Gly Gly Gln Ala Ala Gly Ala Phe Asp Cys Ala Asp Met Ile Tyr 130 135 140 Arg Leu Arg Gln Gln Lys Pro Val Trp Ala Leu Cys Asn Asp Thr Ala 145 150 155 160 Cys Ser Ala Ala Met Leu Leu Ala Ser Ala Cys Ser Arg Arg Leu Val 165 170 175 Thr Gln Thr Ser Arg Ile Gly Ser Ile Gly Val Met Met Ser His Val 180 185 190 Ser Tyr Ala Gly His Leu Ala Gln Ala Gly Val Asp Ile Thr Leu Ile 195 200 205 Tyr Ser Gly Ala His Lys Val Asp Gly Asn Gln Phe Glu Ala Leu Pro 210 215 220 Ala Glu Val Arg Gln Asn Met Gln Gln Arg Ile Asp Ala Ala Arg Arg 225 230 235 240 Met Phe Ala Glu Lys Val Ala Met Phe Thr Gly Leu Ser Val Asp Ala 245 250 255 Val Thr Gly Thr Glu Ala Ala Val Phe Glu Gly Gln Ser Gly Ile Asp 260 265 270 Ala Gly Leu Ala Asp Glu Leu Val Asn Ala Ser Asp Ala Ile Ser Val 275 280 285 Met Ala Thr Ala Leu Asn Ser Asn Val Arg Gly Gly Thr Met Pro Gln 290 295 300 Leu Thr Ala Thr Glu Ala Ala Ala Gln Glu Asn Gln Arg Val Met Gly 305 310 315 320 Ile Leu Thr Cys Gln Glu Ala Lys Gly Arg Glu Gln Leu Ala Thr Met 325 330 335 Leu Ala Gly Gln Gln Gly Met Ser Val Glu Gln Ala Arg Ala Ile Leu 340 345 350 Ala Ala Ala Ala Pro Gln Gln Pro Val Ala Ser Thr Gln Ser Glu Ala 355 360 365 Asp Arg Ile Met Ala Cys Glu Glu Ala Asn Gly Arg Glu Gln Leu Ala 370 375 380 Ala Thr Leu Ala Ala Met Pro Glu Met Thr Val Glu Lys Ala Arg Pro 385 390 395 400 Ile Leu Ala Ala Ser Pro Gln Ala Asp Ala Gly Pro Ser Leu Arg Asp 405 410 415 Gln Ile Met Ala Leu Asp Glu Ala Lys Gly Ala Glu Ala Gln Ala Glu 420 425 430 Gln Leu Ala Ala Cys Pro Gly Met Thr Val Glu Ser Ala Arg Ala Val 435 440 445 Leu Ala Ala Gly Ser Gly Lys Ala Glu Pro Val Ser Ala Ser Thr Thr 450 455 460 Ala Leu Phe Glu Arg Ile Met Ala Asn His Ser Pro Ala Ala Val Gln 465 470 475 480 Gly Gly Val Pro Gln Thr Ser Ala Asp Gly Asp Ala Asp Val Lys Met 485 490 495 Leu Met Ala Met Pro * 500 <210> 465 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34201..34548) <400> 465 Met Val Thr Lys Asn Ile Thr Glu Gln Arg Ala Glu Val Arg Ile Phe 1 5 10 15 Ala Gly Asn Asp Pro Ala His Thr Ala Thr Gly Ser Ser Gly Ile Ser 20 25 30 Ser Ala Thr Pro Ala Leu Thr Pro Leu Met Leu Asp Glu Ala Ser Gly 35 40 45 Lys Leu Val Val Trp Asp Gly Gln Lys Ala Gly Ser Ala Val Gly Ile 50 55 60 Leu Val Leu Pro Leu Glu Gly Thr Glu Thr Val Leu Thr Tyr Tyr Lys 65 70 75 80 Ser Gly Thr Phe Ala Thr Glu Ala Ile Arg Trp Pro Glu Ser Val Asp 85 90 95 Glu His Lys Lys Ala Asn Ala Phe Ala Gly Ser Ala Leu Ser His Ala 100 105 110 Ala Leu Pro * 115 <210> 466 <211> 89 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34606..34872) <400> 466 Met Gly Leu Phe Thr Thr Arg Gln Leu Leu Gly Tyr Thr Glu Gln Lys 1 5 10 15 Val Lys Phe Arg Ala Leu Phe Leu Glu Leu Phe Phe Arg Arg Thr Val 20 25 30 Asn Phe His Thr Glu Glu Val Met Leu Asp Lys Ile Thr Gly Lys Thr 35 40 45 Pro Val Ala Ala Tyr Val Ser Pro Val Val Glu Gly Lys Val Leu Arg 50 55 60 His Arg Gly Gly Glu Thr Arg Val Leu Arg Pro Gly Tyr Val Lys Pro 65 70 75 80 Lys His Glu Phe Pro Trp Ser Arg * 85 <210> 467 <211> 202 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34989..35594) <400> 467 Met Thr Ala Glu Ser Tyr Asp Asp Asn Tyr Leu Asp Asp Glu Asp Ala 1 5 10 15 Asp Trp Thr Ala Thr Gly Gln Gly Gln Lys Ser Ala Gly Asp Thr Ser 20 25 30 Phe Thr Leu Ala Trp Lys Pro Gly Glu Glu Gly Gln Lys Gly Leu Ile 35 40 45 Gly Trp Phe Glu Ser Gly Asp Val Arg Ala Tyr Lys Ile Arg Phe Pro 50 55 60 Asn Gly Thr Val Asp Val Phe Arg Gly Trp Val Ser Ser Ile Gly Lys 65 70 75 80 Ala Val Thr Ala Lys Glu Val Ile Thr Arg Thr Val Lys Val Thr Asn 85 90 95 Val Gly Lys Pro Ser Val Ala Glu Glu Arg Ser Lys Ile Thr Pro Val 100 105 110 Ser Ala Ile Lys Val Thr Pro Thr Ser Gly Thr Val Ala Lys Gly Lys 115 120 125 Thr Thr Thr Leu Thr Val Ser Phe Glu Pro Glu Ser Ala Thr Asp Lys 130 135 140 Thr Phe Arg Ala Val Ser Ala Asp Pro Ser Lys Ala Thr Ile Ser Val 145 150 155 160 Lys Asp Met Thr Ile Thr Val Asn Gly Val Ala Thr Gly Lys Val Gln 165 170 175 Ile Pro Val Val Ser Gly Asn Gly Gln Phe Ala Ala Val Ala Glu Val 180 185 190 Thr Val Thr Glu Ala Gly Ala Ala Gly * 195 200 <210> 468 <211> 168 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35536..36039) <400> 468 Met Val Ser Ser Pro Gln Trp Leu Lys Ser Pro Leu Leu Lys Arg Ala 1 5 10 15 Leu Gln Gly Lys Arg Arg Ser Tyr Met Phe Leu Lys Thr Glu Gln Phe 20 25 30 Glu Tyr Asn Gly Val Ser Val Thr Leu Ser Glu Leu Ser Ala Leu Gln 35 40 45 Arg Ile Glu His Leu Ala Leu Leu Lys Arg Arg Ala Glu Gln Ala Glu 50 55 60 Ser Ser Gly Asn Leu Gln Val Ser Val Glu Asp Leu Val Arg Thr Gly 65 70 75 80 Ala Phe Leu Val Ala Met Ser Leu Trp His Asn His Pro Gln Lys Thr 85 90 95 Gln Ser Pro Ser Met Asn Glu Ala Val Met Lys Ile Glu Gln Glu Val 100 105 110 Leu Thr Thr Trp Pro Ala Asp Ala Ile Ala Arg Ala Glu Asp Val Val 115 120 125 Leu Cys Leu Ser Gly Met Ser Gly Ala Val Arg Pro Asp Thr Asp Ile 130 135 140 Thr Glu Val Ala Lys Asn Asn Thr Leu Thr Asp Asp Asp Phe Ser Ala 145 150 155 160 Gly Lys Ser Ser Thr Ala Ser * 165 <210> 469 <211> 130 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36090..36479) <400> 469 Met Leu Ala Gly Met Thr Ser Thr Glu Tyr Ala Asp Trp His Arg Phe 1 5 10 15 Tyr Arg Thr His Tyr Phe Gln Asp Thr Gln Leu Asp Met His Phe Ser 20 25 30 Gly Leu Thr Tyr Ala Val Leu Ser Leu Phe Phe Cys Asp Pro Asp Met 35 40 45 His Pro Ser Asp Phe Ser Leu Leu Val Pro Arg His Glu Glu Glu Gln 50 55 60 Val Glu Arg Pro Asp Glu Asp Lys Met Leu Met Gln Lys Ala Ala Gly 65 70 75 80 Leu Ala Gly Gly Val Arg Phe Gly Gly Asp Gly Gly Arg Asp Ile Leu 85 90 95 Ser Ser Ala Asp Val Ala Asp Val Met Val Asp Asp Ala Ala Leu Met 100 105 110 Met Ala Ser Ala Gly Ile Pro Gly Gly Val Arg Tyr Val Pro Ala Gly 115 120 125 Trp * <210> 470 <211> 860 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36460..39039) <400> 470 Met Ser Gln Pro Val Gly Asp Leu Val Ile Asp Leu Ser Leu Asp Ala 1 5 10 15 Val Arg Phe Asp Glu Gln Met Ser Arg Val Arg Arg His Phe Ser Gly 20 25 30 Leu Asp Thr Asp Val Arg Lys Thr Ala Ser Ala Val Glu Gln Gly Leu 35 40 45 Ser Arg Gln Ala Leu Ala Ala Gln Lys Ala Gly Ile Ser Val Gly Gln 50 55 60 Tyr Lys Ala Ala Met Arg Thr Leu Pro Ala Gln Phe Thr Asp Ile Ala 65 70 75 80 Thr Gln Leu Ala Gly Gly Gln Asn Pro Trp Leu Ile Leu Leu Gln Gln 85 90 95 Gly Gly Gln Val Lys Asp Ser Phe Gly Gly Met Ile Pro Met Phe Arg 100 105 110 Gly Leu Ala Gly Ala Ile Thr Leu Pro Met Val Gly Val Thr Ser Leu 115 120 125 Ala Val Ala Thr Gly Ala Leu Val Tyr Ala Trp Tyr Gln Gly Asp Ser 130 135 140 Thr Leu Ser Ala Phe Asn Lys Thr Leu Val Leu Ser Gly Asn Gln Ser 145 150 155 160 Gly Leu Thr Ala Asp Arg Met Leu Thr Leu Ser Arg Ala Gly Gln Ala 165 170 175 Ala Gly Leu Thr Phe Asn Gln Ala Arg Glu Ser Leu Ala Ala Leu Val 180 185 190 Asn Ala Gly Val Arg Gly Gly Glu Gln Phe Asp Ala Ile Asn Gln Ser 195 200 205 Val Ala Arg Phe Ala Ser Ala Ser Gly Val Glu Val Asp Lys Val Ala 210 215 220 Glu Ala Phe Gly Lys Leu Thr Thr Asp Pro Thr Ser Gly Leu Ile Ala 225 230 235 240 Met Val Arg Gln Phe Arg Asn Val Thr Ala Glu Gln Ile Ala Tyr Val 245 250 255 Ala Gln Leu Gln Arg Ser Gly Asp Glu Ala Gly Ala Leu Gln Ala Ala 260 265 270 Asn Asp Ile Ala Thr Lys Gly Phe Asp Glu Gln Thr Arg Arg Leu Lys 275 280 285 Glu Asn Met Gly Thr Leu Glu Thr Trp Ala Asp Lys Thr Gly Lys Ala 290 295 300 Phe Lys Ser Met Trp Asp Ala Ile Leu Asp Ile Gly Arg Pro Glu Ser 305 310 315 320 Ser Ala Asp Met Leu Ala Ser Ala Gln Lys Ala Phe Asp Glu Ala Asp 325 330 335 Lys Lys Trp Gln Trp Tyr Gln Ser Arg Ser Gln Arg Arg Gly Lys Thr 340 345 350 Ala Ser Phe Arg Ala Asn Leu Gln Gly Ala Trp Asn Asp Arg Glu Asn 355 360 365 Ala Arg Leu Gly Leu Ala Ala Ala Thr Leu Gln Ser Asp Met Glu Lys 370 375 380 Ala Gly Glu Leu Ala Ala Arg Asp Arg Ala Glu Arg Asp Ala Ser Gln 385 390 395 400 Leu Lys Tyr Thr Gly Glu Ala Gln Lys Ala Tyr Glu Arg Leu Leu Thr 405 410 415 Pro Leu Glu Lys Tyr Thr Ala Arg Gln Glu Glu Leu Asn Lys Ala Leu 420 425 430 Lys Asp Gly Lys Ile Leu Arg Ala Asp Tyr Asn Thr Leu Met Ala Ala 435 440 445 Ala Lys Lys Asp Tyr Glu Ser Thr Leu Lys Lys Pro Lys Ser Ser Gly 450 455 460 Val Lys Val Ser Ala Gly Glu Arg Gln Glu Asp Gln Ala His Ala Ala 465 470 475 480 Leu Leu Ala Leu Glu Thr Glu Leu Arg Thr Leu Glu Lys His Ser Gly 485 490 495 Ala Asn Glu Lys Ile Ser Gln Gln Arg Arg Asp Leu Trp Lys Ala Glu 500 505 510 Asn Gln Tyr Ala Val Leu Lys Glu Ala Ala Thr Lys Arg Gln Leu Ser 515 520 525 Glu Gln Glu Lys Phe Leu Leu Ala His Lys Asp Glu Thr Leu Glu Tyr 530 535 540 Lys Arg Gln Leu Ala Glu Leu Gly Asp Lys Val Glu His Gln Lys Arg 545 550 555 560 Leu Asn Glu Leu Ala Gln Gln Ala Val Arg Phe Glu Glu Gln Gln Ser 565 570 575 Ala Lys Gln Ala Ala Ile Ser Ala Lys Ala Arg Gly Leu Thr Asp Arg 580 585 590 Gln Ala Gln Arg Glu Ser Glu Ala Gln Arg Leu Arg Asp Val Tyr Gly 595 600 605 Asp Asn Pro Ala Ala Leu Ala Lys Ala Thr Ser Ala Leu Lys Asn Thr 610 615 620 Trp Ser Ala Glu Glu Gln Leu Arg Gly Ser Trp Met Ala Gly Leu Lys 625 630 635 640 Ser Gly Trp Gly Glu Trp Ala Glu Ser Ala Thr Asp Ser Phe Ser Gln 645 650 655 Val Lys Ser Ala Ala Thr Gln Thr Phe Asp Gly Ile Ala Gln Asn Met 660 665 670 Ala Ala Met Leu Thr Gly Ala Glu Ala Asp Trp Arg Gly Phe Thr Arg 675 680 685 Ser Val Leu Ser Met Leu Thr Glu Ile Phe Leu Lys Gln Ala Met Val 690 695 700 Gly Ile Val Gly Ser Ile Gly Ser Ala Ile Gly Gly Ala Phe Gly Gly 705 710 715 720 Gly Ala Ser Ala Ser Thr Gly Thr Ala Ile Gln Ala Ala Ala Ala Asn 725 730 735 Phe His Phe Ala Thr Gly Gly Phe Thr Gly Thr Gly Gly Lys Tyr Glu 740 745 750 Pro Ala Gly Ile Val His Arg Gly Glu Phe Val Phe Thr Lys Glu Ala 755 760 765 Thr Ser Arg Ile Gly Val Gly Asn Leu Tyr Arg Leu Met Arg Gly Tyr 770 775 780 Ala Glu Gly Gly Tyr Val Gly Gly Ala Gly Ser Pro Ala Gln Met Arg 785 790 795 800 Arg Ala Glu Gly Ile Asn Phe Asn Gln Asn Asn His Val Val Ile Gln 805 810 815 Asn Asp Gly Thr Asn Gly Gln Ala Gly Pro Gln Leu Met Lys Ala Val 820 825 830 Tyr Asp Met Ala Arg Lys Gly Ala Gln Asp Glu Leu Arg Leu Gln Leu 835 840 845 Arg Asp Gly Gly Met Leu Ser Gly Ser Gly Arg * 850 855 <210> 471 <211> 110 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39036..39365) <400> 471 Met Lys Thr Phe Arg Trp Lys Val Lys Pro Asp Met Glu Val Asn Ser 1 5 10 15 Gln Pro Ser Val Arg Glu Val Arg Phe Gly Asp Gly Tyr Ser Gln Arg 20 25 30 Met Ala Ala Gly Leu Asn Ala Asp Leu Lys Thr Tyr Arg Val Thr Leu 35 40 45 Ser Val Thr Arg Glu Glu Ala Arg His Leu Glu Ala Phe Leu Ala Glu 50 55 60 His Gly Gly Trp Lys Ala Phe Leu Trp Thr Pro Pro Tyr Ala Trp Arg 65 70 75 80 Gln Ile Lys Val Thr Cys Ala Ala Trp Ser Ser Arg Val Arg Met Leu 85 90 95 Arg Val Glu Phe Ser Ala Glu Phe Lys Gln Val Val Asn * 100 105 <210> 472 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39365..40063) <400> 472 Met Gln Asp Ile His Glu Glu Ser Leu Asn Glu Ser Val Lys Ser Glu 1 5 10 15 Gln Ser Pro Arg Val Val Leu Arg Glu Ile Asp Leu Thr Val Gln Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Leu Asn Glu Lys Gly Glu Ala 35 40 45 Val Thr Trp Gln Gly Arg Gln Tyr Gln Val Tyr Pro Ile Asp Gly Ser 50 55 60 Gly Phe Glu Met Asn Gly Lys Gly Ser Ser Ala Arg Pro Ser Leu Thr 65 70 75 80 Val Ser Asn Leu Phe Gly Leu Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Ala Thr Val Val Arg Arg Arg Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Ala Gly Asn Pro Glu Ala Asp Pro Glu 115 120 125 Gln Glu Leu Ser Asp Arg Trp Val Val Glu Gln Met Ser Glu Leu Thr 130 135 140 Ala Met Thr Ala Ser Phe Val Leu Ala Thr Pro Thr Glu Thr Asp Gly 145 150 155 160 Ala Leu Phe Pro Gly Arg Ile Met Leu Ala Asn Thr Cys Met Trp Thr 165 170 175 Tyr Arg Ser Asp Glu Cys Gly Tyr Thr Gly Gly Ala Val Ala Asp Glu 180 185 190 Phe Asp Lys Pro Thr Thr Asp Ile Arg Lys Asp Arg Cys Ser Lys Cys 195 200 205 Met Arg Gly Cys Glu Met Arg Gly Met Val Ala Asn Phe Gly Gly Phe 210 215 220 Leu Ser Ile Asn Lys Leu Ser Gln * 225 230 <210> 473 <211> 212 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40182..40817) <400> 473 Val Asn Ile Ser Ala Glu Pro Glu Ala Tyr Phe Arg Ile Ala Pro Glu 1 5 10 15 Asp Trp Leu Arg Ala Glu Met Gln Gly Glu Ile Val Ala Leu Val His 20 25 30 Ser His Pro Gly Gly Leu Pro Trp Leu Ser Glu Ala Asp Arg Arg Leu 35 40 45 Gln Ile Lys Ser Ala Leu Ser Trp Trp Leu Val Cys Arg Gly Glu Ile 50 55 60 His Lys Phe Arg Cys Val Pro His Leu Thr Gly Arg Leu Phe Glu His 65 70 75 80 Gly Val Thr Asp Cys Tyr Thr Leu Phe Arg Asp Ala Tyr His Leu Ala 85 90 95 Gly Ile Asp Met Pro Asp Phe Glu Arg Glu Asp Asp Trp Trp Arg Asn 100 105 110 Gly Gln Asn Leu Tyr Leu Asp Asn Met Glu Ala Thr Gly Phe Tyr Arg 115 120 125 Ile Ser Leu Pro Ser Ala Gln Pro Gly Asp Ile Leu Leu Cys Cys Phe 130 135 140 Gly Ala Ser Val Ala Asn His Ala Ala Ile Tyr Cys Gly Asn Gly Glu 145 150 155 160 Leu Leu His His Leu Pro Glu Gln Leu Ser Lys Arg Glu Arg Tyr Ser 165 170 175 Glu Lys Trp Gln Arg Arg Thr His Ser Ala Trp Arg His Arg His Trp 180 185 190 His Val Ser Ala Phe Thr Gly Ile Tyr Asn Asp Leu Ala Ala Ala Ser 195 200 205 Ala Cys Met * 210 <210> 474 <211> 227 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40715..41395) <400> 474 Met Ala Thr Thr Asn Ala Phe Ser Leu Ala Ser Pro Pro Leu Ala Arg 1 5 10 15 Ile Cys Leu His Gly Asp Leu Gln Arg Phe Gly Arg Arg Leu Ser Leu 20 25 30 Tyr Val Asn Thr Ala Ala Glu Ala Ile Arg Ala Leu Ser Met Gln Met 35 40 45 Pro Gly Phe Arg Arg Gln Met Asn Glu Gly Trp Tyr Gln Ile Arg Ile 50 55 60 Ala Gly Asp Asp Thr Ala Pro Glu Ala Val Tyr Ala Arg Leu His Glu 65 70 75 80 Gln Leu Gly Glu Gly Thr Val Ile His Ile Val Pro Arg Leu Ala Gly 85 90 95 Ala Gly Lys Gly Gly Leu Gln Ile Val Leu Gly Ala Ala Ala Ile Val 100 105 110 Gly Ser Phe Phe Thr Ala Gly Ala Ser Met Ala Leu Trp Gly Ser Ala 115 120 125 Leu Ala Ala Gly Gly Phe Ser Ala Thr Thr Met Leu Phe Ser Leu Gly 130 135 140 Ala Ser Met Ile Leu Gly Gly Val Ala Gln Met Leu Ala Pro Lys Ala 145 150 155 160 Lys Thr Pro Asp Tyr Arg Ala Thr Asp Asn Gly Arg Gln Asn Thr Tyr 165 170 175 Phe Ser Ser Leu Asp Asn Met Ile Ala Gln Gly Asn Pro Met Pro Val 180 185 190 Pro Tyr Gly Glu Met Leu Val Gly Ser Arg Arg Ile Ser Gln Asp Ile 195 200 205 Ser Thr Arg Asp Glu Gly Gly Asp Gly Lys Val Val Val Ile Gly Arg 210 215 220 Gln Ala * 225 <210> 475 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41349..41555) <400> 475 Met Lys Ala Val Thr Gly Arg Trp Trp Leu Ser Gly Gly Arg His Lys 1 5 10 15 Ser Glu Lys Ile Pro Gln Cys Ser Arg Thr Gly Thr Ala Gly Ala Leu 20 25 30 Arg Arg Leu Ser Val Arg Asn Tyr Ser Tyr Val Thr Thr Lys Thr Leu 35 40 45 Thr Gln Arg Gly Arg Met Cys Arg Ser Phe Gln Gly Glu Arg Ile Tyr 50 55 60 Arg Pro Glu Glu * 65 <210> 476 <211> 176 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41586..42113) <400> 476 Met Lys Cys Lys Ile Ile Ala Ala Ile Ala Met Leu Thr Ala Ala Ser 1 5 10 15 Cys Gly Tyr Ala Ala Glu Gln Glu Val Pro Met Asn Leu Val Ser Ala 20 25 30 Asp Gly Lys Glu Val Ser Ile Gly Lys Ile Thr Ile Gln Glu Thr Pro 35 40 45 Tyr Gly Leu Leu Phe Thr Pro Ala Leu His Ser Leu Ser Glu Gly Ile 50 55 60 His Gly Phe His Val His Glu Lys Gly Asn Cys Ala Pro Ala Leu Lys 65 70 75 80 Asp Gly Lys Pro Val Ala Ala Leu Ser Ala Gly Gly His Phe Asp Pro 85 90 95 Lys Asn Thr Gly Lys His Leu Gly Pro Trp Ser Pro Asp Gly His Pro 100 105 110 Gly Asp Leu Pro Ala Leu Phe Val Thr His Asp Gly Lys Ala Asn Tyr 115 120 125 Pro Val Leu Ala Pro Arg Leu Asn Ser Leu Lys Glu Ile Lys Gly Arg 130 135 140 Ser Leu Met Leu His Ala Gly Gly Asp Asn His His Asp His Pro Glu 145 150 155 160 Pro Leu Gly Gly Gly Gly Ala Arg Met Ala Cys Gly Ile Ile Gln * 165 170 175 <210> 477 <211> 1158 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42247..45720) <400> 477 Met Gly Lys Gly Gly Gly Arg Ala His Thr Pro Val Glu Ala Lys Asp 1 5 10 15 Asn Leu Lys Ser Thr Gln Met Met Ser Val Ile Asp Ala Ile Gly Glu 20 25 30 Gly Pro Ile Glu Gly Pro Val Lys Gly Leu Gln Ser Ile Leu Val Asn 35 40 45 Lys Thr Pro Leu Thr Asp Thr Asp Gly Asn Pro Val Ile His Gly Val 50 55 60 Thr Ala Val Trp Arg Ala Gly Glu Gln Glu Gln Thr Pro Pro Glu Gly 65 70 75 80 Phe Glu Ser Ser Gly Ala Glu Thr Ala Leu Gly Val Glu Val Thr Lys 85 90 95 Ala Lys Pro Val Thr Arg Thr Ile Thr Ser Ala Asn Ile Asp Arg Leu 100 105 110 Arg Val Thr Phe Gly Val Gln Ser Leu Leu Glu Thr Thr Ser Lys Gly 115 120 125 Asp Arg Asn Pro Ser Ser Val Arg Leu Leu Ile Gln Leu Gln Arg Asn 130 135 140 Gly Asn Trp Val Thr Glu Lys Asp Val Thr Ile Asn Gly Lys Thr Thr 145 150 155 160 Ser Gln Phe Leu Ala Ser Val Ile Leu Asp Asn Leu Pro Pro Arg Pro 165 170 175 Phe Asn Ile Arg Met Val Arg Glu Thr Ala Asp Ser Thr Ser Asp Gln 180 185 190 Leu Gln Asn Lys Thr Leu Trp Ser Ser Tyr Thr Glu Ile Ile Asp Val 195 200 205 Lys Gln Cys Tyr Pro Asn Thr Ala Ile Val Gly Leu Gln Val Asp Ala 210 215 220 Glu Gln Phe Gly Gly Gln Gln Met Thr Val Asn Tyr His Ile Arg Gly 225 230 235 240 Arg Ile Ile Gln Val Pro Ser Asn Tyr Asp Pro Glu Lys Arg Thr Tyr 245 250 255 Ser Gly Ile Trp Asp Gly Ser Leu Lys Pro Ala Tyr Ser Asn Asn Pro 260 265 270 Ala Trp Cys Leu Trp Asp Met Leu Thr His Pro Arg Tyr Gly Met Gly 275 280 285 Lys Arg Leu Gly Ala Ala Asp Val Asp Lys Trp Ala Leu Tyr Ala Ile 290 295 300 Ala Gln Tyr Cys Asp Gln Met Val Pro Asp Gly Phe Gly Gly Thr Glu 305 310 315 320 Pro Arg Met Thr Phe Asn Ala Tyr Leu Ser Gln Gln Arg Lys Ala Trp 325 330 335 Asp Val Leu Ser Asp Phe Cys Ser Ala Met Arg Cys Met Pro Val Trp 340 345 350 Asn Gly Gln Thr Leu Thr Phe Val Gln Asp Ser Pro Ser Asp Val Val 355 360 365 Trp Pro Tyr Thr Asn Ser Asp Val Val Val Asp Asp Asn Gly Val Gly 370 375 380 Phe Arg Tyr Ser Phe Ser Ala Leu Lys Asp Arg His Thr Ala Val Glu 385 390 395 400 Val Asn Tyr Thr Asp Pro Gln Asn Gly Trp Gln Thr Ser Thr Glu Leu 405 410 415 Val Glu Asp Pro Glu Ala Ile Leu Arg Tyr Gly Arg Asn Leu Leu Lys 420 425 430 Met Asp Ala Phe Gly Cys Thr Ser Arg Gly Gln Ala His Arg Ala Gly 435 440 445 Leu Trp Val Ile Lys Thr Gly Leu Leu Glu Thr Gln Thr Val Asp Phe 450 455 460 Thr Leu Gly Ser Gln Gly Leu Arg His Thr Pro Gly Asp Ile Ile Glu 465 470 475 480 Ile Cys Asp Asn Asp Tyr Ala Gly Thr Met Thr Gly Gly Arg Val Leu 485 490 495 Ser Ile Asp Ala Ala Ser Arg Thr Leu Thr Leu Asp Arg Glu Val Thr 500 505 510 Leu Pro Glu Thr Gly Ala Ala Thr Val Asn Leu Ile Asn Gly Ser Gly 515 520 525 Lys Pro Val Ser Val Ala Ile Thr Ala His Pro Ala Pro Asp Arg Ile 530 535 540 Gln Val Ser Thr Leu Pro Asp Gly Val Glu Thr Tyr Gly Val Trp Gly 545 550 555 560 Leu Ser Leu Pro Ser Leu Arg Arg Arg Leu Phe Arg Cys Val Ser Ile 565 570 575 Arg Glu Asn Thr Asp Gly Thr Phe Ala Ile Thr Ala Val Gln His Val 580 585 590 Pro Glu Lys Glu Ala Ile Val Asp Asn Gly Ala Arg Phe Glu Pro Gln 595 600 605 Ser Gly Thr Leu Asn Ser Val Ile Pro Pro Ala Val Gln His Leu Thr 610 615 620 Val Glu Val Ser Ala Ala Asp Gly Gln Tyr Leu Ala Gln Ala Lys Trp 625 630 635 640 Asp Thr Pro Arg Val Val Lys Gly Val Arg Phe Ser Leu Arg Leu Thr 645 650 655 Ser Gly Ser Gly Glu Gly Ser Arg Leu Val Thr Thr Ala Ile Thr Ala 660 665 670 Asp Thr Glu His Arg Ser Ser Gly Leu Pro Pro Gly Glu Tyr Thr Leu 675 680 685 Thr Val Arg Ala Ile Asn Ser Tyr Gly Gln Gln Gly Glu Pro Ala Thr 690 695 700 Thr Thr Phe Arg Ile Asn Ala Pro Ala Val Pro Ala Thr Ile Glu Leu 705 710 715 720 Thr Pro Gly Tyr Phe Gln Ile Thr Ala Val Pro Arg Leu Ala Val Tyr 725 730 735 Asp Pro Thr Val Gln Phe Glu Phe Trp Phe Ser Glu Thr Lys Ile Ala 740 745 750 Asp Thr Ser Gln Val Glu Thr Ser Ala Arg Tyr Leu Gly Thr Gly Ser 755 760 765 Gln Trp Ser Val Ser Gly Pro His Ile Lys Pro Gly Lys Asp Phe Trp 770 775 780 Phe Tyr Val Arg Ser Val Asn Leu Val Gly Lys Ser Ala Phe Val Glu 785 790 795 800 Ala Ser Gly Arg Ala Ser Asn Asp Ala Glu Gly Tyr Leu Gly Leu Phe 805 810 815 Arg Glu Lys Ile Gly Lys Leu His Leu Ala Gln Gly Leu Trp Glu Leu 820 825 830 Ile Asp Asn Ser Gln Leu Ala Asp Glu Met Ala Glu Met Lys Thr Ser 835 840 845 Ile Thr Glu Thr Arg Asn Glu Ile Thr Gln Thr Val Ser Lys Thr Leu 850 855 860 Glu Asp Gln Ser Ala Ile Ile Gln Gln Ile Gln Arg Val Gln Lys Asp 865 870 875 880 Thr Asn Asp Asp Leu Ala Ala Leu Tyr Met Leu Lys Val Gln Lys Thr 885 890 895 Lys Asn Gly Ile Pro Tyr Val Ala Gly Ile Gly Ala Gly Ile Glu Asp 900 905 910 Thr Asp Gly Gln Pro Leu Ser Asn Ile Leu Leu Leu Ala Asp Arg Ile 915 920 925 Ala Met Ile Asn Pro Glu Asp Gly Asn Thr Thr Pro Leu Phe Val Ala 930 935 940 Gln Gly Asn Gln Leu Phe Met Asn Asp Val Phe Leu Lys Arg Leu Phe 945 950 955 960 Ala Val Ser Ile Thr Ser Ser Ala Asn Pro Pro Thr Phe Ser Leu Thr 965 970 975 Pro Glu Gly Arg Leu Thr Ala Arg Asn Ala Asp Ile Ser Gly Asn Val 980 985 990 Asn Ala Asn Ser Gly Thr Leu Asn Asn Val Thr Ile Asn Glu Asn Cys 995 1000 1005 Arg Val Leu Gly Lys Leu Ser Ala Asn Gln Ile Glu Gly Asp Leu Val 1010 1015 1020 Lys Thr Val Gly Lys Ala Phe Pro Arg Asp Ser Arg Ala Pro Glu Arg 1025 1030 1035 1040 Trp Pro Ser Gly Thr Ile Thr Val Arg Val Tyr Asp Asp Gln Pro Phe 1045 1050 1055 Asp Arg Gln Ile Val Ile Pro Ala Val Ala Phe Ser Gly Ala Lys His 1060 1065 1070 Glu Arg Glu His Thr Asp Ile Tyr Ser Ser Cys Arg Leu Ile Val Arg 1075 1080 1085 Lys Asn Gly Ala Glu Ile Tyr Asn Arg Thr Ala Leu Asp Asn Thr Leu 1090 1095 1100 Ile Tyr Ser Gly Val Ile Asp Met Pro Ala Gly His Gly His Met Thr 1105 1110 1115 1120 Leu Glu Phe Ser Val Ser Ala Trp Leu Val Asn Asn Trp Tyr Pro Thr 1125 1130 1135 Ala Ser Ile Ser Asp Leu Leu Val Val Val Met Lys Lys Ala Thr Ala 1140 1145 1150 Gly Ile Ser Ile Ser * 1155 <210> 478 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45788..46387) <400> 478 Met Arg Lys Leu Tyr Ala Ala Ile Leu Ser Ala Ala Ile Cys Leu Ala 1 5 10 15 Val Ser Gly Ala Pro Ala Trp Ala Ser Glu His Gln Ser Thr Leu Ser 20 25 30 Ala Gly Tyr Leu His Val Ser Thr Asn Val Pro Gly Ser Asp Glu Leu 35 40 45 Asn Gly Ile Asn Val Lys Tyr Arg Tyr Glu Phe Thr Asp Thr Leu Gly 50 55 60 Met Val Thr Ser Phe Ser Tyr Ala Gly Asp Lys Asn Arg Gln Leu Thr 65 70 75 80 Arg Tyr Ser Asp Thr Arg Trp His Glu Asp Ser Val Arg Asn Arg Trp 85 90 95 Phe Ser Val Met Ala Gly Pro Ser Val Arg Val Asn Glu Trp Phe Ser 100 105 110 Ala Tyr Ala Met Ala Gly Val Ala Tyr Ser Arg Val Ser Thr Phe Ser 115 120 125 Gly Asp Tyr Leu Arg Val Thr Asp Asn Lys Gly Lys Thr His Asp Val 130 135 140 Leu Thr Gly Ser Asp Asp Gly Arg His Ser Asn Thr Ser Leu Ala Trp 145 150 155 160 Gly Ala Gly Val Gln Phe Asn Pro Ile Glu Ser Val Ala Ile Asp Ile 165 170 175 Ala Tyr Glu Gly Ser Gly Ser Gly Asp Trp Arg Thr Asp Gly Phe Ile 180 185 190 Val Gly Val Gly Tyr Lys Phe * 195 <210> 479 <211> 440 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46446..47765) <400> 479 Val Asn Met Ala Val Lys Ile Ser Gly Val Leu Lys Asp Gly Thr Gly 1 5 10 15 Lys Pro Val Glu Asn Cys Thr Ile Gln Leu Lys Ala Arg Arg Asn Ser 20 25 30 Ala Thr Val Val Val Asn Thr Val Ala Ser Glu Asn Pro Asp Glu Ala 35 40 45 Gly Arg Tyr Ser Met Asp Val Glu Tyr Gly Gln Tyr Ser Val Ile Leu 50 55 60 Leu Val Glu Gly Phe Pro Pro Ser His Ala Gly Thr Ile Thr Val Tyr 65 70 75 80 Glu Asp Ser Gln Pro Gly Thr Leu Asn Asp Phe Leu Gly Ala Met Ser 85 90 95 Glu Asp Asp Val Arg Pro Glu Ala Leu Arg Arg Phe Glu Leu Met Val 100 105 110 Glu Glu Ala Ala Arg His Ala Glu Glu Ala Lys Lys Asn Ala Gly Glu 115 120 125 Ala Glu Thr Ser Ala Arg Asn Ala Gly Ile Ser Ala Ser Gln Ala Glu 130 135 140 Glu Ser Ala Ala Asn Ala Asp Thr Ser Ala Gly Asp Ala Ser Glu Ser 145 150 155 160 Ala Arg Gln Ala Ala Glu Ser Ala Ala Ala Ala Lys Gln Ser Glu Glu 165 170 175 Ala Ser Ser Ser Ser Ala Ser Ala Ala Ala Gln Lys Ala Ser Glu Ser 180 185 190 Ser Gln Ser Ala Ala Glu Ala Glu Leu Ser Arg Lys Thr Ala Glu Ser 195 200 205 Ala Ala Gly Asn Ala Ala Arg Asp Ala Thr Thr Ala Thr Glu Lys Ala 210 215 220 Arg Glu Ser Ala Glu Ser Ala Gln Ser Ala Glu Gln Ser Arg Ile Ala 225 230 235 240 Ala Glu Glu Ala Val Asn Arg Ile Pro Thr Val Val Gly Pro Pro Gly 245 250 255 Pro Lys Gly Glu Pro Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp 260 265 270 Lys Gly Glu Arg Gly Asp Thr Gly Pro Ala Gly Ala Thr Gly Glu Arg 275 280 285 Gly Pro Ala Gly Asp Ala Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly 290 295 300 Asp Arg Gly Glu Arg Gly Glu Thr Gly Leu Thr Gly Asn Ala Gly Pro 305 310 315 320 Gln Gly Pro Lys Gly Asp Thr Gly Ala Ala Gly Pro Ala Gly Pro Gln 325 330 335 Gly Pro Lys Gly Glu Thr Gly Ala Ala Gly Pro Val Gly Ala Thr Gly 340 345 350 Pro Gln Gly Pro Lys Gly Asp Pro Gly Glu Thr Gln Ile Arg Phe Arg 355 360 365 Leu Gly Pro Ala Ser Ile Ile Glu Thr Asn Ser His Gly Trp Phe Pro 370 375 380 Gly Thr Asp Gly Ala Leu Ile Thr Gly Leu Thr Phe Leu Ala Pro Lys 385 390 395 400 Asp Ala Thr Arg Val Gln Val Phe Phe Gln His Leu Gln Val Arg Phe 405 410 415 Gly Asp Gly Pro Trp Gln Asp Val Lys Gly Leu Asp Glu Val Gly Ser 420 425 430 Asp Thr Gly Arg Thr Gly Glu * 435 <210> 480 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(47767..48036) <400> 480 Met Asn Ile Leu Lys Lys Ile Met Gln Arg Leu Cys Gly Cys Gly Lys 1 5 10 15 His Asp Asp Cys Glu His Gly Gln Ser Leu Thr Val Gln Leu Arg Leu 20 25 30 Gly Pro Ala Asp Ile Leu Glu Ser Asp Glu Asn Gly Ile Ile Pro Glu 35 40 45 Gln Asp Gly Val Ile Thr Gln Val Val Ile Leu Asp Ala Asp Lys Lys 50 55 60 Gln Ile Gln Cys Val Val Arg Pro Leu Gln Ile Leu Arg Ala Asp Gly 65 70 75 80 Arg Trp Glu Asn Ile Gly Gly Met Lys * 85 <210> 481 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48706..48888) <400> 481 Val Pro Glu Glu Tyr Val Gln Pro Tyr Ser Gly Leu Val Glu Cys His 1 5 10 15 Ala Leu Gln Asp Ala Ala Pro Asp Ala Glu Leu His Gln Val Glu Ala 20 25 30 Asp Val Lys Arg Phe Phe Leu Tyr Leu Thr Glu Tyr Lys Met Trp Asp 35 40 45 Val Glu Val Leu Ile Leu Tyr Lys Asn Phe Leu Pro * 50 55 60 <210> 482 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48161..48730) <400> 482 Met Ala Glu His Ile Pro Pro Ala Pro Asn Trp Pro Ala Pro Pro Pro 1 5 10 15 Pro Val Gln Asn Glu Gln Ser Arg Pro Leu Pro Asp Val Ala Gln Arg 20 25 30 Leu Met Gln His Leu Ala Glu His Gly Ile Gln Pro Ala Arg Asn Met 35 40 45 Ala Glu His Ile Pro Pro Ala Pro Asn Trp Pro Ala Pro Thr Pro Pro 50 55 60 Val Gln Asn Glu Gln Ser Arg Pro Leu Pro Asp Val Ala Gln Arg Leu 65 70 75 80 Met Gln His Leu Ala Glu His Gly Ile Gln Pro Ala Arg Asn Met Ala 85 90 95 Glu His Ile Pro Pro Ala Pro Asn Trp Pro Ala Pro Thr Pro Pro Val 100 105 110 Gln Asn Glu Gln Ser Arg Pro Leu Pro Asp Val Ala Gln Arg Leu Met 115 120 125 Gln His Leu Ala Glu His Gly Ile Gln Pro Ala Arg Asn Met Ala Glu 130 135 140 His Ile Pro Pro Ala Pro Asn Trp Pro Ala Pro Thr Pro Pro Val Gln 145 150 155 160 Asn Glu Gln Ser Arg Pro Leu Pro Asp Val Ala Gln Arg Leu Met Gln 165 170 175 His Leu Ala Glu His Gly Ile Asn Thr Ser Lys Arg Ser * 180 185 <210> 483 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(49369..49551) <400> 483 Met Ser Gly Thr Ser Gly Ser Ser Ser Asp Ala Ala Leu Ala Thr Arg 1 5 10 15 Tyr Ala Ala Glu Tyr Phe Cys Lys Thr Trp Thr Ala Pro Gly Leu Asn 20 25 30 Gln Ala Glu Gly Tyr Lys Ala Ile Ser Asp Leu Ser His His Tyr Phe 35 40 45 Arg Ala Glu Gly Ser Ser Pro Pro Gln Ser Phe Leu * 50 55 60 <210> 484 <211> 48423 <212> DNA <213> Escherichia coli O157:H7 <400> 484 cctttttatt cataaggcgg gacactttca ggattttgaa tttattcaat tttttccttt 60 ctccaaaatc tctccaaaac gtttccccaa aactaggcca cgcattttac aacacttttt 120 tcctgagatg gtgacggata ttccatatgg tgtttgtcaa ataaccaact taacccattc 180 ctgacctcga gtatcgttat agcgatcggt ggttgcctgg actttatgtc ctagtaatgt 240 ttttgtatcg ataccctgtg cacggtacag ccgttctgat agagagcgtt gttcatgaaa 300 tgttggcgga gtttttcctg ctggtggaat taccccagcc agatcccgtg ctttggcaaa 360 gtagtcgctc aggttgtctt tactcatcgg cttcggttgt ttctggtgcc gactatggat 420 tagatatgga cttaatattc tgtctcggca cccatcaata acttctttta acgttatccc 480 aatggcatca cagcgtagtg taagcggtaa cgccagacgc attccggttt ttccctgggt 540 gatatgcaag tgttcgttcc acacatctga aaaacgcatg tggcaaatgt catcacggcg 600 ctgaccagta acaatcgcaa gaagcattgc gttacggata aagtgttttt caggcgttgc 660 attgtaaatt ttttgccagt cttccatggt gagcctggct ctggttactt tagggatcgg 720 tttacgggta gcctccggag gattccatcc aggaggaact tcccctgcat gctgtgcttc 780 tttataaata tcaacccata atccacgatt tactctcgct gtactgacca tgtctttatc 840 cagccactca tccagtatta atgcaaagtc tcttacttcc agttctttca atgggtggtt 900 tcccagacgg gaaaccaggt atgcagccat tcgagttttt tctttgtgag ttgtagctgc 960 aatatctcca tttttcagtc gcgtgtcctg tattttcaga tatcgatcaa cccatgcctt 1020 taatctgata ccccgacgtt ttgttgctga cggactttca tcaattttgc gcatgaaata 1080 ttcagcttct gctgcagcta ttcgctgatt ggctgtggaa gcgatttttt ctgccttacc 1140 tttgtctgtt ccgagtccgt gaaattttcc agtcacagga tttttatact ggtagtaaac 1200 tctgccagtt ctgcgatcaa acttttcgta aagaccggct acgtcagtgc tgttttttcg 1260 tggcctcggt gacatgagtt aaaatctcct tcagtgcatc atcatcgcca gtatgaattt 1320 ccggcgcaat tcccgtttca ccaggcccaa caaatactgc tcggcgatct atcagccaac 1380 gcccacgaat tttttgtggt cttggaacga tgtatcctag ttttccgtat ttcaccaggg 1440 tagtgtttgt tattgggaga ctgaaccgtt ttggtttcca ctcgtcgagc gttatcaggt 1500 actgttcgct catggctatc actccggaac gcgccagttg cagaatatca acgacaactg 1560 gcgacggttg aacattaaaa atcagcctga ctcgggatca gtttttgcca gataactgaa 1620 acgtattttg cctggtaacg ggcgtcatca agtgcattat ggcgctcacc ttcgaatgga 1680 atagccgttc tggcatcgaa gtctatggct ttccccagct caacgattgt gcgtacatcg 1740 cgatcgttgt agtaacgcca cgggcagggg atcccctgcc gttcgtatga acggcgcaaa 1800 atcgtgttgt cgaagttggc tccatttccc cagacctgaa caaaaaattc accggagttt 1860 tcgtcgataa attcccgcaa ttgtaacagt gcatcatcta acgggatttc atcggtcata 1920 atggcagatt gcgcttcgcg tgattgctta agccaccatt taatggtgtc cctcgccgtg 1980 tgctttcgtg ttgtgtgcct gctttttacc acgtcaggcg aggtggtccc cgttattccc 2040 caacaacaag gatcttgtta atctggatat ccccaacaac aataagagta ttgaatgtga 2100 tcgctgaatt aacggcagca atgacggcta ttcgtgaaac cgcccagatt gcaaaactaa 2160 tgaacgaggc aaaaactcaa gctgaagtaa atgcggctat tggtgaactg aactcaaagc 2220 ttgcatctat tcagcgcgaa tgcgtgtctc tcgttgagct ggtgggcact tatcaagaaa 2280 taaatgcttc tctcaaagct aaaattgcag aatttgaaaa ctttgaggct cagacggaag 2340 gttatatcct tagccaactt gagtcgggaa cttttgtgta ctcgaaggag gtaaccgtga 2400 acggcggcag cataatcatg catctttgtc caaaatgttt tggacaaaag atagtatcga 2460 tacttcagcc attcccggtt agagaatatg aattttttca taaaagcagg tgcctgtact 2520 gtgaaaatca gtttcttatg aataaaaatc cggattacgt atcacctcca tctattgaag 2580 agttggccag aaaactgaac ggcaatctgt agatttttac tgttatggat atccagattg 2640 ttaaagagca tgccggatgc ttgcttgtgt ccggcgcgtg tgcaccactc tccccccgtg 2700 gaggattcct taattaccag atttcattag tcagagtttc ttgctaacca gcgacgcgcg 2760 ccagattcgg ttttaaacgt tttgcttttg gtatacgtca tcgcggtgaa cgtgccgtcc 2820 tggttgggaa acacgccgca caccagagat tcgttgttgc caagatcaag agtatccatg 2880 ctgacctcat atccccttaa cgccggggta gcggaacaaa aacctgctgc atagttaaag 2940 ttgaaccctg ccgtcatgtt cttacgcctc gggctggcta cttaatccct gaccactgcc 3000 gggtaactct aggtattgcc ctgtattgtg tgggacggga tgggttggta tgggaaaact 3060 ataggaaatg cctaattgct tgtcaatagg ctacgcctaa tgatttgggt gcgacctaat 3120 aggtgatggt ttgtgggaga ggtagtagga gttaactaac gggaactagg aatttcccgt 3180 cggaccatat aagtttaagt tcctgtcttg gtgatgttct ggcttttccg ttttgattct 3240 tgatttttca gatagttagc taccttcatt tccattgcgg caatgtaggc acgaacgtca 3300 tgatcaaccc aactaggctc cgtagcattt ccagataaga ggaaagccac aattgctctt 3360 ttttcatcag aggcggcttg ataaaggctg tttatgtcta aaagttcact ttttgtatct 3420 gaagtggatg gggttggtat ggggtattcg ttaagccccc aatgctctgg accaaccaca 3480 tcagaaaaga aacgccatag ttctggaagt ttgtctttac ttatcgaacc tttcttaatc 3540 cagtcatgga ttgatggtgg ttggactttg aaatgacgtg cgatttccgc ctttgatttg 3600 acggctcctg atgcaatttt tttgttaatg gcctgctcta tcgctcggcc taagtcttta 3660 ccactaagca ttgcttaata gtctcctatg cgcatcgcat taggcaatgc ctactctcga 3720 agtgttaggc atagcctatt gacaattgca ttaggctaag cctaatatta ttgtgtgttt 3780 tttggagttc attcgatgaa aaaagataac tattcattca aacgagcttg tgctgttgtc 3840 ggtgggcaat cagcaatggc taggctttta ggtgtatctc ctccaagcgt aaatcaatgg 3900 atcaaaggtg tacgtcagtt gcctgctgag agatgtcctg cgattgaacg agcaacaaaa 3960 ggtggtgtcc tgtgtgaaga acttcgtcct gatgttgatt ggacatactt acgacgctcg 4020 tcatgttatt cgcagaatat gtcgatgaag caaccaaatg acgaaaacga tcatacccga 4080 agcatcaaga ggcaaatgat tcatgaaaat caaacatgag cacatccgca tggcgatgaa 4140 tgcctgggca tatcctgatg gtgagaaagt tcctgcagct gaaatagccc ggacttattt 4200 cgaactgggg atgacgttcc cggaactgta cgacgacagc catccggaag ccctggctcg 4260 taatacccag aaaattttcc gttggctgga taaagacacc cctgatgctg ttgaaaaaat 4320 gcaggctctg ttaccggcga tcgaaaaggc aatgccgcct ctgctggtgg cccgtatgcg 4380 cagtcacagc tctgaatatt accgtgagat cgtcgaacgg agggatcggc tggtgaaaga 4440 tgtggatgat tttgtcgcag cggcgatcgc ctggggcacc ctgactaaca gtgggggtca 4500 gcctggtaat gctgttgtcg tgcattgacc aacaatattc atgccggatt tcttccggat 4560 gttcgagggt aaagttcggt atcagatgag gtgagtatgg ctaatgcctg gctcagattg 4620 tggcatgaca tgccaaatga tcccaaatgg cgaaccattg ccagggtctc aggacagcca 4680 atcgcaacag tgatggcggt gtatatccac cttctggtga gtgcgtcacg aaatgtcacg 4740 aaatgtcacg gcgagtcact acgtggtcac attgatgtca cgacggaaga tttagcaagt 4800 gcgcttgatg tgacggaaga cgtgattgat tcaattttgc atgcaatgca ggggcgagtt 4860 ctggatggcg atcttatttc cggatgggaa aaacgccagg tgatgaagga ggataacggt 4920 aatgtttcgc aaaccgcaaa atccccggca gagcgcaaga gagcgcagcg ggagcgggaa 4980 agactgcggg agcagaacac tgattgtcac gatgagtcac gacgcgtcac gcatatgtca 5040 cgacaagtca cgacagatac agatacagat aaagaattaa accccacaca taacgcgcgc 5100 atgcgcgaga gtgctccagc cagtgagtcg aatggcgcgc cgttgcagac agcagaacct 5160 gaatacccgg atggcctgag cgaaccgatc gggaaatttc cgatgactgg tgtctggcgg 5220 ccgtcgctgg attttcgaca gcgggctgca ttgtggggta tggctctgcc tgagcctgag 5280 tttacacctg ctgagcttgc cgcattccgg gattactgga tggcggaggg gaaggttttc 5340 acgcaggttc agtgggagca gaaatttgcc cgtcacgtgc agcacgtcag ggcacaggta 5400 aaaccagtca gcaagggggt aagccatgca gcaccaggtg gcaccgcatc acgggcagtt 5460 caggaaattc gggcagcacg tgaacagtgg gaacgtgaaa acggatttat cagcaacgga 5520 aacggcctgg aagctgtggg aacttatggg ggaggtgtat tcgaaccgct ggacccagaa 5580 gaacggggct gcgccgtcga agctctggat tgctcagatt ggcgcgatga ctgaacagca 5640 aatccggcag gtctgccgtc agtgcatgga ccgctgccgg gcgggtgaaa cgtggcctcc 5700 ggacctggct gagtttgtgg cgttgatttc ggagagcggg gcaaatccat ttggcctgac 5760 ggtggatgcc gtgatggagg agtaccgtcg ctggaggaat gaatcctggc ggtacgacgg 5820 gagtgataaa tacccgtggc cacagccggt gctgtaccac atttgcctcg agatgcgtga 5880 cagagggatt gagcggcaga tgacggaagg tgagttaaaa cgacttgcag aacggcaact 5940 gacgaaatgg gcaaagcaag ttggtaacgg gatgagtatt cccccgatcc ggagacaact 6000 cgcatcgccg aagtgcccgc aagggccaac gccaattgaa ttactgaaac aggaatacga 6060 gcgccggaag gcggctggtt ttgtttgaat ctgagaaacg attttgtcgg aggaaatttt 6120 aatggaaacc gtatctgacg cactgaaagc actgaaaaga gcctcttcac atgtggtggc 6180 agctcgcctt ggaattagtc gtgaagaggc tgtcaacgaa ctgtggaaac tgaaacgccg 6240 tggagaagcg gataacaagg gggcgatatg gtggctgact caggctggtg aaagtgaacc 6300 ggtgtcaccg gtaccgaaag tgacggcgca aatgctgaca gaggcgattg aacaacatgg 6360 cccacaaacg gcggatgaac tggcattgat gttcggaatt acctcccgcc gggcgaattc 6420 atcgctggca atggcaatca gcaaagggtg tctgattcgc gtgaatcagg atggtaaatt 6480 tcgttactgc ataccgggcg ttgatttacc ggcagagccg aaagcagcat ccgtagctga 6540 aacggagggt aaagcccttc ctcagccagc tggtgttgcg ttaccagtcc aggaaacggc 6600 tgcacaggaa gaaattaaaa cagaagcggt ggaggacatt gtgaagttgc agcaatcgtt 6660 cactgaagcg aaagcagatg acctgattct accatcgctg catgtggcta accgcgagct 6720 gcgccgggcg aaaagtaatg ttcagaagtg ggagcgagtc tgtgctgcgc tacgggaact 6780 gaacaaacac agggatattc tccgggatat taccgccacc agagagcagc agcggtgagt 6840 ggctggaaga agtggcgctg ggctgaaatc ctgatactcc ggcagtgtgc gggaacgatg 6900 agagtcgaaa gcatcggtta tctgattggc cgtagtgagt cagccgtcag gacgaaagcg 6960 cgggaactgg gtatcagcat gatgttacgg ggtgattatc accagtcagc caaatgttca 7020 cagcgtgata ttgagctggc gtggcaactg catcagcgtg gtgtaccccg acgggaaatt 7080 gccgaaaagt ttgggatgaa gttgggcgca gtgaataact acgtttattt cgacaggagg 7140 gttcaggagt gagggtgagg gtttatatcg ccggtccgat gacgggatat gaaaatttta 7200 accgcgaggc atttcacaaa acggaagagg tgctgaaacg ggaagggcat accgttttaa 7260 acccggcagt acttccggac gggctgactc agccacacta catggatatt tgcatggcaa 7320 tgctccgttg cgtggatgcg gtttacatgc tgaaaggctg gcagcagtcg gcaggtgcag 7380 gggctgagct ggcactggag gagaaaccgg gccatgcggt gatttttcag gaggtgggca 7440 gtgaatattg acccggcgat aacgattgat atggccctga acgccggcct ggcacttctt 7500 ggttatttct acattatgtt ctgcagcgga cgatggctgt cactgttgtt catgaaaaaa 7560 tggaataaac gccgtaagca ggagcaacgc cagaaggcaa tggatgcatt tttcgaagcc 7620 ttcggaattg acggcatgga accaggggat ccagctcgcg caatcagcag agggggtgta 7680 gtaatccttg tatatcggag tgaagagaaa aatgacgatc acaaaacaac gtgtagaaga 7740 aatcatatcc cgcattgaaa tgtatggaca tggtgcaggg tatatcgcag acgaggttaa 7800 tgatctggct atactggcgc tgaatttatc aaatatcgcg aacctgaagc gatacgagct 7860 tgatatggga ggttgcgact cgtgcggtca ggattgtggc gctgatatga ctgaagatcc 7920 tgatggtgat tatgtcctgt ttgatgacgt ggttaagttg tttgaatttg atacaaccac 7980 tcaaaagtta gaaatcccgg caaaggaggc agccagtggg caagattgac tatcaggcac 8040 tgcgtgaggc agcacaaaac tatcaatcga cgctggcgtg gtatcaggct accccggaca 8100 gcccaaatgc tgaacgggat tgtgatgcgg ctcttgctgc gtttaagcgt cacatccgtc 8160 atcgggaagc ggatattatc gctgatttgc tggatggact ggaagaagca aaatcacaac 8220 tcaacgagca gcgtgagtat tacgaaggcg ttatctctga tgggagcaag cgtattgctg 8280 aactggaagc gcgggaagtt caattaccga ctcgctacga ccttcgatat ggacacccga 8340 taaatgcaga tgagcgacat gtcatgatac ctaaagaaaa tggcagttgg ctttacctga 8400 ttgacctaga acacgcatta cgcgtcgctg gcattcgcat caaaggagag tgagatgaac 8460 ggacaaatat caattgttcg accaggagca tgtgacgatc gcgaaatacg aatgattatt 8520 cgtctggcga tggggaaaac aataactgct ctcattactc cagaaaatct cgcattagca 8580 ttaacaggaa agtcagacat gccagtagag ctaaagctgc gaaatgttga gattaaggtg 8640 aaatagctat gaccactatt accaaagatc gactgctgac aatccagcat tggcgcgaaa 8700 catacggacc gggtagcaac gttgtgcttc cagcagaaga agcggaagag ctggcacgga 8760 ttgcgctggc atcactggca gcagtatcgg atgaacgagc agcctatgaa ttatttatgg 8820 agaagcgttt cggagaatct gtagatcgcc gcagagcaaa aaatggcgat agagattaca 8880 tggtatggga tatggcgctt ggctggatta tctggtgtca ccgcgccgcc atgcttcagg 8940 ctggaaactt tcgggaaaat aagggttcgt caaccaataa ttttcgggaa atctcggaaa 9000 cgtcaaccaa ctatccggta actccggatg gttggataag ctgtagtgag cgaatgccgg 9060 atgatggtca gcacgtaatt attttatgtg atggcgcatt cgttctttat gcgcaatatc 9120 gagacggtga gttttttgat gtagtccgta atggtgatga atttttcgaa acacagagcc 9180 gcaatgtaac cgactggatg ccgctaccag aaccgccgca ggaggtgcgc caatgatctg 9240 gcctgaagcc tttgcaatta caggcgttgc tatagctatt gattttttag tatatgttat 9300 ttgtcggtgg gggtaaaaac gttcgccggg attcacacca aaggagggaa tatgtcggat 9360 gatatttcac tggcaatgga aggtgcgctg gctgttattg ctgttgtggg cgtttactgc 9420 ctggttgtgt ttttgatgga tcgactaggg aactgaattc attacgatat gggaattccc 9480 atatcgggta aaaacggttt gcggtaaagc gagagttaag tagaattgct gcgggtgctt 9540 gaggctgtct gcctcgggca tgccaccgta aggtagacag agaaaagccc cagttaacat 9600 tacgcgtcct gcaagacgcc taacattaat ctgaggccaa tttcatgcta gacacatgta 9660 ggttagcctc ttacgcgccg aaaggcaagg agaagcaggc tatgaagcag caaaaggcga 9720 tgttaatcgc cctgatcgtc atctgtatca ccgtcatagt gacggcactg gtaacgagga 9780 aagacctctg cgaggtacga atccgaaccg gccagacgga ggtcgctgtc ttcacagctt 9840 acgaacctga ggagtaagag acctggcggg ggagaaatcc ctcgccacct ctgatgaatc 9900 aggcatcctc aacgcacccg cacttaaccc gcttcggcgg gttttgtttt ttcctggcat 9960 tctggtttac aattcgcacg ccagcctgaa caactggcac ctgctgcgcc agcagagaca 1002 0 accgatggcg cacgatacca aattatacaa ttctgatgat tctgccgtct ttgccagcag 1008 0 gcgcggacgg tgttttcacg cattcaaatc tgactggtac cagcatcccc catgcactga 1014 0 agaacaggcc gaatggctca ttcagtgtta ccgcaggcgc ggatgcgagg ttaaaaaagc 1020 0 ccttagcctc gactaccgtc actggataat ctccgtcagg ctcccttact ccgaacggcc 1026 0 accgcgtccg tcccgcacat tccagcaacg gatctggagg taatgtgcgg gtattacttc 1032 0 gacctgttct ggtaccggaa ctcggtctgg ttatcgttaa gccaggccgt gaatcaatgt 1038 0 cagcattcca taacggcaga atactggtgg agccggaacc aaaaagcatg cgagctctgc 1044 0 cgtccggggt tgtacctgcc gttcaccagc cgctggcgga agataaatca ctactgccat 1050 0 ttttcagcga tgagcgggtg atccgtgctg cgggtggcgc tggtgcactg tctgactggt 1056 0 tattacgtca cgtgaaatcc tgccagtggc tacacggtga ttatcatcat agcgaaaccg 1062 0 tcattcaccg ttacggtacc ggcgcgatgg tgttgtgctg gcactgcgac aaccagctgc 1068 0 gggagcagac atctgattca ctggatcaac ttgctcaaca gaatctggcc gcctggatga 1074 0 ttgacatcat ccgtcacgca atgaatggcg cacaggagcg tgaattatct ctggctgaat 1080 0 tatcctggtg ggcggtccgc aatcaggtgg cggacgcgct accggaagcg gtattacgtc 1086 0 gttcgctggg gttgcgtgcg gaaaaaatcc gctccgtata ccgtgaaagc gacatcatac 1092 0 cgggagaaca gaccgccacc agcatactga agcagcgcac aaaaaatatt gcgctaccgt 1098 0 ctcacaccca ccagcaacag aacccaccac aggaaaagac ggtggtcagc attgccgttg 1104 0 atccggagtc tccggaatcc ttcaggaaac gacctaaacg tcgccgctgg gtaaatgaga 1110 0 aatacacacg ctgggtaaag acacagccgt gtgcgtgttg tggtaagcca gcggacgatc 1116 0 ctcatcatct gattggtcat ggtcagggcg gaatgggaac aaaatcccac gatattttca 1122 0 cgctaccgct gtgtcgggag catcacaacg agcttcatgc ggatccgctg gcgttcgaag 1128 0 aaaagcatgg ttcccaggtt gatttaattt ttcgttttct tgatcacgcc tttgcaaccg 1134 0 gcgtgctcgg gtaaaagagg ttactgatgc gtatagagtt tgttttgctt tacccgccga 1140 0 cggtgaacac ctactggcga cgtcgtggca gcacatattt tgtatcaaaa gccggtgagc 1146 0 gttatcgccg ggctgtggcg cttattgttc gccagcagcg gctgaaatta agcctgtccg 1152 0 gaaggctggc gataaagatt attgccgagc caccggataa gcgccgccgt gacctggaca 1158 0 atattctgaa agcgccgctg gatgcgctga cgcatgcggg gttgctaatg gacgatgagc 1164 0 agtttgatga aatcaatatc gttcgtgctc agccagtatc tggtggacgt ctgggggtga 1170 0 agatttaccc cataatgctt gaagggcagg tcaaaaaatg aaactggaag atttaccgaa 1176 0 atactactcc ccaaaatccc ccggcctgac tgatgcatcg gcctcaacgt cgaaagatac 1182 0 gctgagtatc actgatgtga tggccgcgca gggcatgaca cagaattggg ctgagatggg 1188 0 gttttctgcg ttccttggga aaatgggcat tagtatgaat gacagagagc gggcaacaga 1194 0 attgctgaca gaatatgcac tcagtcggtg tgatcgcgtg gcggcgttaa gaaaactccc 1200 0 ggcagaaata aaaccggcag tgatgcgtat tatggcttcg tatgcgtttg aagattatgc 1206 0 ccgtagcgcg gcgagcaaaa aacagtgccc ctgttgtcac ggaaaaaaat ttattgaaag 1212 0 cgaggttttt acaaacaaga tccagtatcc ggatggtaag ccgccagtgt gggcaaagtg 1218 0 cacaaaaggc gtgtatccgt cttactggga ggaatggaaa aaagtcaggg aggtggtaaa 1224 0 agttgcctgt ccggagtgtg gagggaaggg ggaggtttcc accgcctgta aagattttcg 1230 0 tgggcgcggt gttgccattc atcgtgaaga gtcggtaaaa cgtggtatgc ctgttatcag 1236 0 agactgccag cgttgtggtg gtcgtggcta tgaaagatta ccttcaacgg aggcatttaa 1242 0 tgccatatgt aatgtaaccg atgccatatc tcttgataca tggaaaaaaa cagttaaacg 1248 0 tttttacgat acgctggtgg tgcagtttga tattgaagaa gcatgggcag aacaacaact 1254 0 gaaaaaggtg accagatagc tttgttgatt tttcccgaat ctgtggtaaa tttgccctaa 1260 0 cgatgggcgt tttatgcctg acgttagaag attttttaca cccgtcgcca ggcgggtttt 1266 0 tttatgactg aaatcacgcc agtacagtaa acgcgctggt ggttgtgaat accggtcttt 1272 0 ctgcttgctg gctttttcga caagagttat tggtgtgtca cgttaaccgg aaaaaggaaa 1278 0 gtttgagaaa cgcgatctgg cacaggcggt gattaacgcc gcatacctgg tggcctgtgc 1284 0 agatggtgaa tgtgaggctt cctagaaagc gaagatcgaa caggtactgc gtaatcagcc 1290 0 agcgctgtcc gcgtttacgt cagaaattaa tgcgattagc gcaaccatta tcggtcagct 1296 0 ggatacgaac tttaaaactg gtcgtcgtgc ggcgttacgt gagatcgagg atgtgaaaca 1302 0 cgatacgcgt gaagcggaag atgtgctgga tgtggcggtg gccattgcgg aggcagacgg 1308 0 cgaaattgag ccggaagagc gcaaggtgct ggaagagatt gccggtgttc tgggtcttcg 1314 0 tctggagaat tacctgtgac ggtaaaactg cgtctggctg tggctgcact cctgctgttt 1320 0 ctggtggtga tggtggattt caccagcaga atcatgtcgg tgctggcgga tggggggctg 1326 0 gtctgcggca ttgtggtatt gctgtggccg gtgataaaaa gaaacagcct gcataatgct 1332 0 tgattttttt gtttactgtt tattaaaaat actactgcat ggcgaatccc cctgtgcgga 1338 0 ggggcaatca gcaaccaggt atatgggata atcgcggatt caggtgctgg tactgaattc 1344 0 accgggaggc acccggcacc atgctttgcc acaaaagtgt tatttctgtt tttctcaaac 1350 0 tatcatcgtt atccctttat ttccggctgc gcatggcgcg gccttttttt tacgaccagc 1356 0 cactggcaga tggtcatcct gtgatttgat tccggttccg gctttttaac tctgttcctg 1362 0 tacacgggag aaattcgatg tcgattaaac attatgatgt tgtcagggcg gcgtcgccgt 1368 0 cagatcttgc ggaaaagctg acacacaaac tgaaagaggg ctggcagccg tttggtagtc 1374 0 ctgtggccat aaccccttat accctgatgc aggcgattgc cgcggagggg gatgtgacca 1380 0 cgccagtggt tgtgcccggc acgggggatg gtggctatcc gggagtggtc accacggagc 1386 0 cagattatta ctacgttatt ccactggccg ggcagtcgaa cggcatggct tacggtgagg 1392 0 ggcttcctct gccgcagaca tatgaccgtc ctgacccgcg tataaagcaa ctggctcgtc 1398 0 gcagcacagt gacgccggat ggcgctccct gtaaatataa cgacattatt ccggcagacc 1404 0 actgtctgca tgatgtacag gacatgagcc gtcttaacca tccgaaagct gacctgtcga 1410 0 aaggtcagta cggaaccgtg gggcaggggc tgcatattgc caaaaagctg ctgccgttta 1416 0 taccggcgaa tgcgggtatt cttctggttc cgtgctgccg tggtggttca gctttcacca 1422 0 ccggggcaga tggaacatac agtgacgtga ccggtgcctc agagagttct acccgctggg 1428 0 gtgtgggcag gccgctgtat aaggatctca tcggtcgtac aaaagccgcg ctggcaaaga 1434 0 acccgaaaaa tgtgctgctt gccgtggtgt ggatgcaggg ggaatttgac tttgacggaa 1440 0 cgccagcaaa tcacacagcc cgttttacag aagtagtgga acaatatcgt acggaccttg 1446 0 cagatatggt gggacagtgc gctggtggtt ctgctgacgg tgttccctgg atatgtggag 1452 0 acacaactta tttctggaag cagaagagcg aatccactta ccagacggtg tacggcagtt 1458 0 acaaaaacaa aacggaaaag aatattcact ttgtgccgtt catgaccgat gagaacggag 1464 0 caaatgtccc gacgaacaaa ccggaagaag acccggatat tccggcatca ggatattacg 1470 0 gtgcggcctc ccggacgtcg gcaaactgga cgtcagcaga ccgtgcgagc catttcagct 1476 0 catgggcacg cagggggatt atttctgacc gtcttgcctc agcgattctt ctccatgcag 1482 0 gacggacggc tgaactggtg ggtggggaac aggttgtgat gccgccggat gagaagccgt 1488 0 caccggacac accatcaaca ccgtcaacgg acgggaaatc agtgacaacg ctgctttatt 1494 0 accgtgcaac agagtcaggt ggtttactga atccgcaggg atggggagct gaaggagggc 1500 0 gtgcattggt agttgatgat gcaggtgctg caggaggtaa ggcgctgagg tggaccaaac 1506 0 agacaggaag ttcctcgtgg tttatgcagc atgatgccgg taatggcgca gacctgctgg 1512 0 agaagggcgg gcttatcagt tgtcgtttta aagttgatgg cacactgaca gctaatcagt 1518 0 acgcactggc gctgtactgg ccggtttctt cactgcctca gggcgtcaca ctggaaggta 1524 0 atgccggtca taacctgctg gcgtcgtttt acgtacagag cgatgccaca gaccttaatg 1530 0 tgatgtacca caagggaaat gctggtcaga acacgaagct ggggtcattc ggcgcatttg 1536 0 ataacgaatg gcatacgctg ggcttccgtt ttgccggtaa caacagtatt gaggtgacgc 1542 0 cggtcattga tggtaaggac gggacgccgt tcatgctgtc acagtcaccg gtcggcacgt 1548 0 ttacggcaga caaattgcgc gtgaccgata tcactagcgg tgcgacatat ccggtgctga 1554 0 ttgaaagtat aacagtggaa gtgaataacc cgtaagcagg aaaaaaaggc cgccggggca 1560 0 gggaaaacaa ggagccagaa ccggcggcaa atgtcgttat atccaaagca aaacatgcag 1566 0 gacacttttt taaccaacag gtattaacga tgtcaacacc atatcaataa ccgggaggga 1572 0 taatgagatt tgtacagctt attttattgt atttctgcac ggtggtgtgc acgttatatc 1578 0 tggtaagtgg cgggtataag gttatccgga actatatacg caaaaagatt gatgccgcgg 1584 0 cggcggaaaa aatcagcgcc agccagtcag ccggaacaaa acccgaagag cctctcattt 1590 0 cgtagcaact ttcttaacaa cacctttcaa cgagaaaatc ccatgtcaga aataaaatct 1596 0 ctggtcactg ctgaagcagt gaaggacgtc ctgcgctctg aagaagtcag aagcgcactg 1602 0 aaacagcaac tccgccagaa tcttgaggcg cgtcttgatg ctgaagtgga tgccattctg 1608 0 gatgagctgc tggggggacc ggctgctcct gagcctgaag acggcgcggg tgacagtgct 1614 0 gtttcagatg gcgttgtgtc tcagcctgac ggtagcagtg agcctcagcc tggcggcgaa 1620 0 atgatgatgt aaccatacgc aggggctgtc ggtgtgagct gatgcccctc ctgttgttgt 1626 0 gagcttccgg attgcgggag acggggtatg taccagatgg aaaaaatcac aacgggtgtg 1632 0 tcatacacca cgtcagcggt ggggacggga tactggttac tgcagctgct ggacaaagtc 1638 0 tctccgtccc agtgggtggc gataggtgtg ctggggagtc tgctgtttgg cctgctgacg 1644 0 tatctgacta acctgtattt caaaatcaga gaggaccgtc gtaaggcggc gcggggagag 1650 0 taaagcgatg aagaaaaaat acgaactggt tgttaaaggg ataaataatt acccggataa 1656 0 gattactgtt actgtggcac tggaaattgg tgggtatccg tcactgttgt tgccagatgt 1662 0 ggcgattagt cttgaccgta ctgaaggtgc cacgctggag ttttacgaag ctgaggcgaa 1668 0 aaagcaggcg aagcagtttt tcatggatgt tgctgccggg ttatgtgaag gggatggtcc 1674 0 gttaccggaa aagcgtcccg taattttaga ggcgcaggat gtgttgataa cctacagagg 1680 0 aaaactaccg ggaataatta cgggttctct gaagactcca ccgctggcct gaagacttaa 1686 0 catatccagg gatttgaaat cgataaaccc tgataaatat ccatgaacgc aaaaatcaga 1692 0 tacggcctgt cggctgccgt tctggcgctg attggtgcag gggcgtctgc gcctgaaatc 1698 0 ctcgaccagt ttctggatga aaaggaaggt aaccacacca cagcataccg tgatggtgcg 1704 0 ggtatctgga ccatctgccg tggagccacc cgggtggatg gtaagcctgt tattcctggc 1710 0 atgaagctgt cgaaggaaaa atgcgaccgg gttaacgcca ttgagcgtga taaggcgctg 1716 0 gcatgggtgg agaaaaacat cagagtgcca ctgaccgaac cccagaaagc ggggattgcg 1722 0 tcattctgtc cgtacaacat tggccccggt aagtgtttcc cgtcgacgtt ttacagacgg 1728 0 attaatgcag gagatcgaaa aggtgcctgc gaagctattc gctggtggat taaggacggt 1734 0 ggcagggact gccgtattcg ctcaaataac tgttacggtc aggtatcccg tcgtgaccag 1740 0 gagagcgcgc tggcgtgctg gggaatcgac agataagcag aatattttgc tgaaaaatga 1746 0 ggtttgctta catggacgga taacacgaaa tcctgcaaat tggcaaaatg taagtgaata 1752 0 aagtcaaaac agttgtttaa cactcaggca ccgtaatgat gcctttgtca tttctgcgca 1758 0 tctcacgcgc atctcacaac acagaacctt tcaggatgac ccttgaggat accggtttgg 1764 0 ctgtcggtgc ctttctgtgg gctggattcc tgtgagacaa ggttcatcac taaaaggaaa 1770 0 taaccgatga atatgatggc cgtgccgttt cacggcaact ctctttatgt agttaaccat 1776 0 aatggcgaac catacgttcc catgaaacct gtcgttgcgg ggatggggct ggcctggcaa 1782 0 tcacagttgg ctaagttaag acagcgtttt gcgtcaacta taacggaaat cgttatggtt 1788 0 gctgaggatg ggaaacaacg caatatggtg tccatgccac ttcgaaaact tgccggctgg 1794 0 ctacaaacca ttaatcccaa caaagtaaaa cccgaaatcc gcgataaggt catccggtat 1800 0 caggaagagt gcgacgatgt tctttacgag tactggacga agggttttgt cgttaatccc 1806 0 cgtaaaatga gcgtgatgga agaactcaac caggcttgtg ctgacatgaa acgggataaa 1812 0 aacattgcca gtgtgtttgc taccgggctg aatgagtgga aacaggttaa agccgcgcat 1818 0 gtatcaaaaa tccgtacgct ggtaaatgaa gcgaatatgc tgattgattt tgtcctggct 1824 0 gatacaggca aagggaaaat aacaaaggcg gattgatggg gtggctaatg atatcagata 1830 0 aactcataac gctggtgaag agcctctgtg tacttgtcgg catttcattt ttagtcatgc 1836 0 tggttgccat tttcttttcc accgcctggc gagtcctgac gttatcggga ctggtggggt 1842 0 gaaagagaga tgaaccgtgt tctgtgtgtg gtgattattg tcatggcggt tggctgtggt 1848 0 gcgctgtggc tggcaacaaa ccattaccgt gacaacgcgc tcacctacaa agcgcagcgc 1854 0 gataaaaaag ccagagagct ggaacaggcg aatgccacca ttactgacat gcaggtgcgc 1860 0 cagcgtgatg ttgctgcgct cgatgcaaaa tactcgaggg aattagccga tgcgagagct 1866 0 gaaaatgaaa ctctgcgtgc tgatgttgcc gctggtcgta agcgcctgcg gatcaacgcc 1872 0 acctgccccg gtaccgtgcg tgaagccacc ggcacctccg gcgtgggcaa tgatgccgcc 1878 0 gtcgaactct ctccggttgc tggacgaaac gttctcggta tcagagacgg aatcatcagc 1884 0 gaccaggcag cattgagaat gcttcaggaa tatatccgca ctcagtgtat taactagtat 1890 0 ttttgttatt cggagaatgc atgaagaaat tattggtaac cgtaaagcct tttcagggaa 1896 0 caattccgtt ccgtattttg cagcgtggtc gtgttcttgt tgaaggttcg ttcagtggta 1902 0 aatgtacgca attacactcc aggacctttc aggtgaatgc cacgaatgaa gagctaaccg 1908 0 ttgagtgtac gatgaatgcc gctaaatgcc gcatggtatc cgctgcatta cagccagtgt 1914 0 gttgagcgac cttattattc atgcgcggta ttgtcgccgt attcctgcat taacagagac 1920 0 cgcagcccga ccgggagaat cctctgcgcg agtgtgcggg gataatcaaa aacgatacac 1926 0 accggggttt accgcgttaa cggagcgcgg cgttgtcccc tcatggtcgc tggtccggtg 1932 0 cgatggtgga agaagccgga tgtttatcac tattaattga taacacagaa atggattcat 1938 0 tgattttcag cacgtttttg tattcgtatt attgaacatc tgtttatttt acttttaaca 1944 0 tattgataat aaaaagagct gtaaatcttt agatgagtcg attttgtccg aggaagttca 1950 0 aatggatttt atgctgacgg tttctggtgt ggttatcctg tccattgctt atactgcaga 1956 0 taaatatggc tgccatttgt tatcacgtat tggcgcttat tgctcgttga tgctgatttt 1962 0 ctcgtcgctt ttttttgagt aagttatatt aattataaca aataattttc tgtgtttttt 1968 0 caggctatcc cgtcagacgg gaagcctgta ctgccggggg acgaatggaa aactgatgtg 1974 0 tccggtaact gtgtgttctg tgaacaccat gttacttaat tatgtaattc atacccgaac 1980 0 gctctgttga cagccttctt ctgcaggctt caataaccca cgctgaaaag ttaccggaac 1986 0 ctttatgttc aagggcgata ttgatctgtt caatcatgtg attggggaaa cggatattgc 1992 0 ggattgtggt tctgcggggc cggtttttcg atgacatttt ctttcctctg gtgacaagct 1998 0 atatggcgag gattttacat ggctgtgctt cgtacgttac cgggcagaat caaaactctg 2004 0 aacacccggc ggataaatgt cctgaggggg gaacagcgtc gtgtcagtgg cagtgcccgg 2010 0 gtttccctca aacgtcgtat ctggcggagg gatgccggac actgttgtct ctgtagacgc 2016 0 gtggttgacc tttgtgacag tgaactcgat caccgcattg cacttcagtt cggtggtggt 2022 0 aatgaggaga cgaacctctg gaccctctgt actgaatgcc atcgccagaa gtcagcgagt 2028 0 gaagcggcga gtggtatgcc tgatccgacg ttgcctgagc ttcctgatgg cacgctcagg 2034 0 gccgacggaa tcactggcct gtgaccagac ccggggggga tcatccggcg aaaaaaaacg 2040 0 atcgccctgg acaccgcgcc ccctctcacg cagagaaaaa attcccgttt cagggcagtt 2046 0 aacatgttaa ctggctgccc gggcattttt gcggttttta tctttattat tcagtttgtt 2052 0 gtgcggaaaa aatgttaaca ggctttttca gcaaatgtta accaggcagc agttaacatt 2058 0 tgcggcatga gacgccggga aaaatgggct gaaccatacc cggctgagtg cgttctggac 2064 0 ccgggaggag gctgtgctga caacgcaaaa acgaaaattt gcgctggcgc tcatgtccgg 2070 0 gaaaaacaaa acagcgtcag cccttgccgc cggttattcg gcgaagacag ccagggttaa 2076 0 aggctcgcag ctggcaaaag atccggaggt gcttgcgttt atagcccgta aacagtgcga 2082 0 gacggtggag gtggatgagg ttcctgttta tcggcagaaa aaatcagagc cggaggataa 2088 0 accccgtcgc cgtgaggcgg ctgcaatacc acagccggac gaaacaaatc cggagatgcc 2094 0 accgcccgtg gtgatatctc ctggtattga gtatatggag gacggtcttc ccgatccggt 2100 0 gaaagcgatg gggcgtcttc tggtggagaa cattaatacc gaccccaggc tggcgctgga 2106 0 tgcggcttat aagctggcgc agttcacgca ccacaaaaaa ggggatgccg gtaaaaaatc 2112 0 ggcaaaaggt gacgcggcga aaaaagcggc taaccgtttt gcggtgccac caccaccccg 2118 0 cctggtggtg aataatgata atgagggcaa cggatgatac ctgtgtggag cacggcctgc 2124 0 ccggactggg cagagcgcct gaaaaagggg ctgtcgatta ttccggctcc gatttatccg 2130 0 gagcaggccg cacatgccct ggcgattttt aaacaactgc ggattgtgga tgcaccgggc 2136 0 agcccgacgt tcggggagtc ctgcgcacag tgggtgtttg acctggtggc ggccctgttt 2142 0 ggctcctacg atgcgcagac cggtgtacgc catatcaagg aagtttttat ccttatcccc 2148 0 aagaaaaaca gcaagtccac gctggctgcc gggatcatga tgacggcgct gttactgaac 2154 0 tggcggcagg cggcgggcta caccattctg gccccgaccg tggaggtggc ggctaacgcc 2160 0 ttcaaccctg ccagggatat ggtacgacgg gacgatgatc tggatgacct ctgtcaggtg 2166 0 cagacacata tccggaccat cacccacagg gtgacggaca ccaccctgaa ggtggtggct 2172 0 gccgatccga atacggtatc cggtatcaag tccgtgggga cgctgattga tgaactgtgg 2178 0 ttatttggca agcagtacaa agcggaggac atgttacgtg aagccatagg cggccttgcc 2184 0 tcccgcccgg aagggtttgt ggtgtatacg accacccagt cgaatgagcc gccagccggg 2190 0 gtgttcagac agaaactgca gtacgcccgg gatgtccgtg acggcaaaat tcatgatccg 2196 0 cactttctgc cggtgatttt tgagcatcct cctgaaatgg tggaaagcgg ggctcacctg 2202 0 ctgatggaaa acctcgccat ggttaacccg aatctcggtt attcggtgga tgaggctttt 2208 0 ctgtaccggg agtaccgtaa agcccgggag gctggtgagg aagcatttcg tggcttcatg 2214 0 tcaaaacatg ccaatgtgga aattggtctt gccctgcgtt ctgaccgctg ggcgggtgcg 2220 0 gatttctggg agcagcaggg caggcgcgtc agcctggacg atatcctgca gcgcgctgat 2226 0 gtggtgacgg tggggattga cggcgggggc ctggatgatc tgctgggaat gtacgtgatt 2232 0 ggccgtgaca gggaaacccg cgaatggctg ggctggggcc atgcctgggc gcatgaaacc 2238 0 gcggtggtcc gacggaagag cgaggcgtcc cggtttcagg atcttgttgc ctgtggagat 2244 0 atgaccattg tccggcgtgt cggggatgac acggcggaag tggcggaata tgtgcgtcgc 2250 0 attcatgagg ctgagttact ggaccatatc ggtattgacc cgtcaggggt ggggcagatt 2256 0 ctggattcac tggcggaagc cgggatcccc gacggaattg tggtggggat aagccagggc 2262 0 tggaaactgg gcggggccat taaaaccacc gagcgcaaac tggctgaagg ggtgctggtg 2268 0 catggtgacc agcccctgat ggcctggtgt gtcggcaatg cccgggtgga gcctaaaggt 2274 0 aacgccattc ttatcaccaa acaggccagt ggacggggaa aaattgaccc gctgatggcg 2280 0 ctgttcaatg cggtctccct gatgtccctt aacccggaac cgaaaaagaa agaatatgcg 2286 0 gtttttttca tataaccctg ttcacactgt aaccatcatg aaccgctgcg gcggtttttt 2292 0 tattttcagg aggctgatgt gactcttaaa cgggcctgtt ccctgctgac ggtgaaatcc 2298 0 ttcagtgagg atgaacgggt gatcaccggg attgcgtcaa cgccttctcc ggatcgggat 2304 0 ggtgacatcc tggagccgga gggcgcggag tttggcagtg cgatcccgtt tctctggcag 2310 0 catgaccatt cccgcccggt ggggcagtgt acggtgcgcc gggtcagcga agggctggaa 2316 0 atcacggcaa cactggtgaa gcccgtaccg gatatgccgt cgcaactggc tgcccggctg 2322 0 gatgaggtct gggcggccat taagaccggg ctggtcaggg ggctgtccgt gggcttccgt 2328 0 ccccatgaat acacctttct ggacggaggc ggactgcatt ttctgcgctg ggaactgatg 2334 0 gaggtgtctg ccgtcaccgt gcccgcgaat gcggaatgca ccatccggac cattaaatct 2340 0 tacgaccgcc cgttttctgc cgcgtccggc aaccggaaac cggtggtgaa aatcgcatct 2346 0 tctgccggcg ctgcggcaca gtcaacaacc gtttttcata aggaaaagac cataatgaat 2352 0 attggcgaac agattaaaag ttttgaaaac aagcgtgcag cgctggcagc ctcccttgag 2358 0 gaggtcatga ccaaagccgc agaggaaggg cgcacgctgg atgtggagga ggaagagcat 2364 0 tacgacaaca ccgcagcgga aatccgtcag gtggatgcgc acctgaagcg cctgcgtgaa 2370 0 ctggaagccg gtaaggccgc cacggcgcag ccggtgaaac aggccggtaa cgggaatgtg 2376 0 gccgcggtgg cttctgcgcc ggtgatccgt gtggagcaga aactggataa ggggattggc 2382 0 ttcgcccgct ttgccaaatc gctggctgcg gctaaaggcg tccgatctga agccctggaa 2388 0 gtggcccgtc gtcagtatcc ggatgacagt cgtctgcatc atgtcctgaa atcggcagtg 2394 0 ggcgcgggga ccaccacgga tccgcagtgg gcaggcagcc tgtctgaata tcaggaatac 2400 0 gcacaggact ttattgatta cctgcgtccg cagaccatta tcgggcgatt tggtcagggc 2406 0 gggatccctg cacttcgtca ggtgccattc aatatccgtg tgcacgccca ggtgtccggc 2412 0 ggtgctgccg gctgggtggg tgagggtaag gcaaaacccc tgacgaagtt tgattttgaa 2418 0 tccatcacct tcagtcatgc gaaggtgtcg gccattgcgg tactgacgga agaattgatc 2424 0 cgtttttcca gtccggctgc tgatgcactg gtccgtaatg cgctggcgga agcggtggtg 2430 0 gcgcgtctgg atacagactt tgtggacccg aaaaaagccg cagtggcaga tgtctccccg 2436 0 gcgtccatca cccatgatgt gaagggcacg gcatcaaccg gtaacccgga tgcggatgcc 2442 0 gaggctgcgt ttggacagtt tgtggcagca aacctgcagc ccaccggtgc ggtctggctg 2448 0 atgtccagca ccaatgccct ggcactgtcc atgcgtaaaa atgcgctggg tcagaaggaa 2454 0 tacccggaca tgaccctgct gggtggctcc ttccaggggc tgccggtgat tgtctcccag 2460 0 tacgtgggtg accagctggt gctggtgaat gccccggata tttatctggc ggatgacggc 2466 0 ggcgtggcag tggatatgtc ccgcgaggca tcactggaaa tgcagtctga gccgggcggc 2472 0 gacagtacca cgccgtcccc ggtggagctg gtttccatgt tccagacagg cagcgtggcc 2478 0 atccgtgcgg agcgctggat caactggcgt cgtcgccgta ctgcggcggt ggcggtgatc 2484 0 accggagtga actacggcag tgcgtccggc ggctgagtct gataaggagg acgggaggcg 2490 0 tgcgcctccc gtaacaggtt atggcaaaga tccgatatct gcagggcacg catgatgccc 2496 0 gggccgggga tatccgtgat gtggcacagc cgtgtgcgga ggtgctggtt cgcctgggaa 2502 0 aggcggagta catcacggtg cgacgtccgg caggtcagaa aaagaaacgt gatgcggagc 2508 0 atggcgaatg tggaaccttt tacggcgaac ccgaaaaaac cagaaatcag gacgtgacgt 2514 0 aagagaggcg ggctggacca gcctgtttca ggcggtggct gagccctttt ccggcgcctg 2520 0 gcagcagggc gtgaaagccg atcctgaagc cgtcctctcc tttcatgcgg tgtttgcatg 2526 0 tatttcgctg atatcccagg atatcgccaa aatgcggctg cgtcttatgc agacggatgc 2532 0 gcatgggata cgcagggaaa cgcgccgggg ggatattgcc cgcctctgtc gtcgtcccaa 2538 0 cgcccagcag aaccgcatcc agttttttga actgtggctg aacgccaaac tgcgtcatgg 2544 0 caatacggtg gtgctgaaaa tccgtaatgc ccgggggcag atcaaagaac tgcgtattct 2550 0 ggactggagc cgggttgaac ctctggtggc ggatgacggc gaggtgttct accgcatcac 2556 0 gccggaccgg aactgcggga tcacggaggc ggtgacggtg cctgcccggg aagtgatcca 2562 0 cgaccggttt aactgttttt ttcatccgct tataggattg ccgccggtgt atgccgccgg 2568 0 gctggcggcc acgcaggggc atcatattca ggaaaattcg acgtcttttt tcagaaatgg 2574 0 cggcaggccg tccggggtga ttgagatccc cggcagtatt acggaagaaa atgcgaaaaa 2580 0 actgaagagc aactgggaca gcgggtatac aggcgaaaat gcggggaaaa cggccattct 2586 0 gagcaacggg gcaaaataca accccacgac gttttcaccg gtggatgcgc agacggtgga 2592 0 acaactgaag atgaccgctg aaattgtctg ttcggtgttc cgtgtcccgg cctacaagat 2598 0 tggcgtggga caaccgcctt ccagtgacaa cgtggaggcg ctggagcagc agtattattc 2604 0 ccagtgcctg cagacgctga ttgagtccat tgaactgtta ctggatgagg cgctggaaac 2610 0 gggggaaaac gagagtacag aatttgatgt caccacgctg ctgagaatgg acagtgagcg 2616 0 gcgcatgaaa acgctggggg atgcggtgaa aaatacgctt ctcacgccca atgaggcccg 2622 0 taaacgggag aacctgccgc ccctggccgg cggtgatgca ctgtatcttc agcagcagaa 2628 0 ctacagtctg gaggcgctgt cccgtcgtga tgcccgtgag gatccgttcg cgtctgccgg 2634 0 gaaaacagtt tcatcacagc tgcctgacgg cgcatctgac ggtaataagg caatcagtga 2640 0 aacagagcat gatgcggtga aagcgatgtt caggggggat actgagaaaa tgacggaacg 2646 0 ggaactgtcc attattcgtg cactgggaga agaattttcc acagtgctgg cggatttaca 2652 0 gcgcacattt gaggagaaaa tagccgcgca ggcacaaacg tttgaagaaa aactggcttc 2658 0 tcagtctgtg gtattacaga agtgcgtgac gggtgatgat gtgcgtccga tgcttgagca 2664 0 gatggtgaaa gaggcagtga gccatattcc tgttccgcgc gacggtcgtg actacgatcc 2670 0 ggatgttctg cagaaggcgg tgaatgatgc ggttgcgaat attccggtac cggcagacgg 2676 0 caaaagtatc accccggatg atgtgcgtcc gatgcttgag cagatggtga aagaggcagt 2682 0 gagccatatt cctgttccgc gcgacggtcg tgactacgat ccggatgttc tgcagaaggc 2688 0 ggtgaatgat gcggtcgcga aaataccggt accggcagac ggtaaaagta tcactccgga 2694 0 tgatgtgcat ccgatgcttg aacagatggt gaaggaggcg gtaagccata ttcctgttcc 2700 0 gcgtgatggt cgtgactacg atccggatgt tctgcagaag gcggtgaatg atgcggtcgc 2706 0 gaaaataccg gtaccggcag acggtaaaag tatcactccg gatgatgtgc atccgatgct 2712 0 tgaacagatg gtgaaggagg cggtaagcca tattcctgtt ccgcgtgatg gtcgtgacta 2718 0 cgatccggat gttctgcaga aggcggttct ggaggcggtg agtgccctgc cggctccgca 2724 0 ggacgggcgt gatgccacgg cactggaaat actccccgcc attgacgatc aaaaatcctt 2730 0 tccccggggc tcgtatgcca cacaccaggg tggactctgg cgggcgtatg aaaaaacgta 2736 0 cgggatgcgg ggatgggaat gcctggttga cggggtggcg gatattgacg tcagcatgac 2742 0 gggtgaacgg tcgttctctg tggtggtccg gcagagcagt ggccagcgta cggaaaaaac 2748 0 attttccctg ccggtgatgc tctaccgtgg tgtgttcaga atcggcgaaa cttaccaccc 2754 0 cggcgatacg gtgacgtggg gggctcgttg tggcactgca acagtatgac cggtgataag 2760 0 cccggagaag ctcattcatc aggctggact ctggctgcaa aacgtgggcg ggatgcagga 2766 0 ggtggaaagt gacagcatta ctgacactgg aagaaatcaa ggcacatctg cgtgttgacc 2772 0 atgacgcgga tgatgagatg ctgatggaca aggttcgtca ggctaccgcc gtgctgctgg 2778 0 cctacatcca gggcagccgg gataaagtga ttagtgagga cggtgagctg atccctggtg 2784 0 aggcattaac ccggatgaag ggggctgcca tgcgactgac cgggatgctg taccggaatc 2790 0 cggatcttgc tgagcgggaa gacctcgtgc agggggaact gccgttttct gtttccgtgc 2796 0 tgatttacga tttgcgttgt ccgacggtgt tatgaggagg gggaatggca atatctgcag 2802 0 gtcgtctgac acagatgatc agtgttctga acccggtgtt aacccgtaat gctgccggag 2808 0 aaatgacgga agaatgggtg tcatgcggga aaattcatgc ggatatccgg ggcaggagca 2814 0 gccgggagcg gatgcagtcc ggtgcggaaa tggcgcaggc ggaaatccgc atctgggtac 2820 0 gcggtcagtc tggtcgtgaa atcacggcgg cgtcacgact tcatgtgctg agtggtccct 2826 0 ggcgtgacca tgtcctgaat gtcgtcgggg tcccggttcc ggatgcaacc ggcgggcgtc 2832 0 tggaaattct ctgtcggctg ggaggggaaa aatgatcgaa accctgctgg atttttcggg 2838 0 gctggaggac atcagccgcg atttgcagct tctgagtggt gcggaaaata accgggtgct 2844 0 gcgtgaggca acccgtgcgg gtgcgaatgt gctgaaagaa gaagtggtgt cacgggcacc 2850 0 ggtacgcagg ggaaaacttc gccgcaatgt ggtggtcctt tcccggtgct cccgcgatgg 2856 0 cgggatggaa tccggtgtgc atatccgggg tgttaatccg gacaccggta acagcgataa 2862 0 caccatgaag gcggataacc cgcgcaatgc tttctactgg cggtttgtgg aaatggggac 2868 0 cgtgaatatg ccaccgcacc cgtttgtgcg cccggcattt gatgtgcgca gtgaacaggc 2874 0 ggcacaggtg gcgattgctc ggatgaaccg ggccattgat gaggtactga gacgatgacg 2880 0 gaggcggatt tgtatcctca tctggcgcat cttgccggcg ggcaggtgta cccgtatgtg 2886 0 gtccccctgc tggatggcag gccgtcggtg gcgcttccgt gggtggtttt cagcctgatt 2892 0 tcatcggtgt cggcggacgt gatgggcggg caggcggagt cctcagtgtc ggtgcagata 2898 0 gacgtttatg ccgggactgt gacgcaggcg cgtcagatac gtcaggacgc ccgtgaagcc 2904 0 ataatgctgc tggccccggg atccgtcagt gaaatgcagg actatattcc ggaaaaccgc 2910 0 tgttaccgtg caaccctgga gtttcaggtc acggtgtaat tttttcaaca gaacccataa 2916 0 cccgccgcgt gcgggttttt tattatcagg aggcagaatg tctgctttgt atgaacgttc 2922 0 acagctgacg caggtgatga tttcatctgc cccggcgact gctgaaacca tggagaaggc 2928 0 ggaatatctg cgcctggact gcaccatcaa ggaagtccag ttcaccgccg gtcagaaaca 2934 0 ggatattgat gtgaccacgc tctgctccac agagcaggag aacatcaacg gtctgggggc 2940 0 gtcgtccgag atttccatgt cgggtaattt ttatctgaat caggcccaga acgccctgcg 2946 0 tgatgcctat gacaatgaca cggtgtatgc gtttaaggtg cagtttccgt ccggtaaggg 2952 0 ctttaagttc ctggcggaag tgcgtcagca cacctggtca tccggtacca acggcgtggt 2958 0 ggctgcaacg ttttcacttc gcctgaaggg taaaccggtg tcctatgtgg taccgctggc 2964 0 gtttgtgaaa aatctggata agacacttac cgtgaatacc ggtgcgctgc tgacaatgtc 2970 0 agtcagtgtc aacgggggaa cgccgcctta taaacacgcc tggaagaagg atggtcagcc 2976 0 ggtagaggga cagactactg acactttcag taagccaggt gcgcagtcag gtgataaggg 2982 0 ggcttatacc tgcgaggtaa cggattctgc agaacagccg cagagcatta cctctgatgc 2988 0 gtgtacagta acggttaatg gtgcgggcgg ataaggctta tggcaaaaga tctgaaaaca 2994 0 ctggcgctgg ccagactgtc ggggttccgt cataaaacgg tgaaggtgcc ggaatggaga 3000 0 aatgtcagcg tggtgctgcg ggagccttcg gcagaggcct ggtatctgtg gcaggaagtg 3006 0 ctcaatggtg atggagagga tgacgatacc ctgtcggtgg tggcgaaaac ccgccgtaac 3012 0 ctggaagcgg atgtgacgct gttctgcgat gtcctgtgtg atactgacct gcaacgggtg 3018 0 ttcactccgg acgaccgtga gcaggtgctg gccgtctatg gtccggtaca tgcccggttg 3024 0 ctgcgtcagg cactggaact gatcgctgat gcagagtcgg ccagaaaaaa gtagcccgcc 3030 0 cggaaattcg ctttctgatg cgacttgcgc tccgtctggg gcgcacctta tccgaactgc 3036 0 ggcacagcct gagtgcgagc gaggcgatga tgtggatgga gttcgacagg gtatccccgc 3042 0 tgggtgatga gcgcggggat atccgtaatg cacagatcgt gaaagcggtt ttcggggcac 3048 0 aggggatgaa tgttgcactg aaggacgcca tgctctgctg gggcgaggat gaggataagc 3054 0 cggaggtgga tccgtttgcg gcgctggaag acgcgctgag ccttgcagca atgtcataaa 3060 0 taatgatgaa aacctgctgt ggcaggtttt tttttgcccg gagaaaggtg aatggcgacg 3066 0 ttacgtgaac tgattatcaa aatttcggca aattcacagt cattccagtc ggagatccag 3072 0 cgggcgtccc gtatgggcag tgaatattac cggaccctgc agaatggcgg gcgtcaggcc 3078 0 gctgcggcag cccgggagca gcgacgtgcc ctggcagaac tgaacagcca gttgacggaa 3084 0 attcgcggtt ctgctgtcgg aatggctggc gcatttgccg gtgcctttgc ctccggacac 3090 0 ctgatttcac tggcggatga gtggagctcc gtgaatgccc gtctgaaaca ggcatcacag 3096 0 tcatccgatg aatttgcgtc atcacagaaa gtgctgatgg atatcagcca gcggacaggc 3102 0 accgcatttt cggataatgc ggccctgttt gcccgttcgg cctgcctcga tgcgtgaata 3108 0 tggttacagt gccggtgatg tactgaaggt gacggaggcc atttccacgg ggctgaaaat 3114 0 ctccggtgcc agtacggctg aggcgggttc ggtgatcacc cagttcagcc aggcgctggc 3120 0 acagggtgtg ttgcgcggtg aggaatttaa ttcggtcaat gaaagtggtg accggatcgt 3126 0 acgtgcactg gctgcgggta tgggcgtggc ccgtaaagat ctgaaggcaa tggcggatga 3132 0 cggaaaactg acagcggata aagtggtccc cgcgttaatc agccagctgg ggatattacg 3138 0 tgatgaatat gcggccatgc cggaaacggt ttccagtagt atcacgaagg tggaaaacgc 3144 0 ctttatggcc tgggtgggcg gtgcgaatga ggccagcggg gtgacaaaaa cgctctccgg 3150 0 catgctgaac ggtgttgccg gacagattga taatgtggca acagccgtgg gcgcgctggt 3156 0 tgccgtcggg gttgcacgtt actttggcaa tatggcctcc ggagcgatgt ctgccacggc 3162 0 aggacttgtg acggctgcac gtaatgaagt tgcactggcg gaagcacagt tcaggggaac 3168 0 gcagattgcc acggcgcggg caagggcagc cgtgtaccgt gctcagcagg ccgtggcggc 3174 0 agcccgcggg acggagatgc agattgcagc agaggcccgt ctggcggcca cacaggaacg 3180 0 cctgaacaga aatattgctg ccagaaccgc cgcccagaat gcgctgaaca gtacaacggc 3186 0 ggtgggctca cgtctgatga gcggtgcgct ggggctggtt ggtggcgtac ccggactggt 3192 0 gatgctgggg gctgcagcat ggtacacgct gtaccagaat caggagcagg ctagggagtc 3198 0 tgcgcgccag tatgcactga cgatagatga aatcgcgcat aaaacgccgt caatgtctct 3204 0 gcctgaagcc tcagataatg aaggacgaac acgggcggcg ctgacagagc agaaccggct 3210 0 gattgatgaa caggccagtc gggtgaaatc cctgcaggaa aaaatcgcag gatatcagta 3216 0 tgttctggcg aacccgggct ggacgaccgg tgacggattc atgataaacc atctgacatc 3222 0 ggtgaagacc gtaacggaag ggcttgctca ggcaacagag cagcttgccg ttgagcagtc 3228 0 ccgtctggca cagatgcagg aaaaagcgca gtccattcag gatgtgcttg ccgggctgga 3234 0 agaccgtcgt gtggcgttaa ttcgtcagca ggcggcagag cagaataagg tgtaccagtc 3240 0 catgctggtt atgaacggtc agcatacgga attcaaccgt ctgctggggc tggggaatga 3246 0 actgcttcag cagcgtcagg gactggtgaa tgtaccgtta cggctgccgc aggccaccct 3252 0 ggatgataaa cagcagagtg ccctgacaaa aacagagcgt gagctggccc tgtccagact 3258 0 gaaaggggaa gaaaaagagc gtgtccgact ggggtatgcg gcggatgacc tcggttttgt 3264 0 gggtgatccg tatcaggagg cgagacaacg ttatatcagt aatgccctgg aagcctggcg 3270 0 caataacgag gcgaataaac ccaaatcccg gggtggaaaa tcagagacgg aaaaagcgga 3276 0 agacagtttt tcccggctgc tgaagcagca gaaagagcaa ctggcactgg tggggcagaa 3282 0 tacagagctg gcgaagctga aataccagac agcgctgggt gaactgaaaa ccctgacgga 3288 0 gatgcagaag caggaactgc tgcgtaacgc gaccctgatt gaccagcaaa aaatccggga 3294 0 acagttgcga tcccgggaag agacactgaa gaatgagaat gcggctgcgc gtgcgtcgaa 3300 0 tgatgctgaa ctgctggggt acgggcaggg ggagcgagcc agagaacgca tgcgggagtt 3306 0 gcagcagatc cgcgacagct tccgccagaa ggatgcggac cttcagtctc agtatcagac 3312 0 cggggatatc agtgaggatt tttacagaca ggctctggca cagaacgcgc agtatctgag 3318 0 cgaacgcctt aaggaccagg cagtctttta tgccgaatcg gatgtgcagc gtgcggactg 3324 0 gcagaaaggg ctgcaggagg gattcagtaa ctgggtggat aatgcgtccg attacgcctc 3330 0 acaggcagca cagctggcga cggagggtat ctcagggatg gtgaataaca tcacggagat 3336 0 gctgaacgga aataaagtgg aatggcgcag ctgggcctca tcagtgctgc aggaaatatc 3342 0 aaaagttctt atgaatgccg cgattgtcaa cggaattaag acggcggcaa acggtatgtc 3348 0 cggtgcggga ggatttctcg gcagcattgg tgactggctg ggcggagcgg tggccaatgc 3354 0 aaaaggcggc gtgtatacct cggcaaacct gagcgcgtac agcaacagca ttgtggacac 3360 0 gcccacgtac tttgcgtttg caaaaggggc cgggctgatg ggggaagccg gacctgaagc 3366 0 tattatgccc ctgacccggg cggcggatgg ctcgctgggc gtacgcgccg tgggcagtat 3372 0 gaacggcagt gctggtctgg tgtattcccc ggtctaccac atcgccattc agaatgacgg 3378 0 ggctaacgga cagatagggc cggaggcggc aggcagtctt gtgcagctga ttgaccagcg 3384 0 ggtgcaggcg gtgatgctgt ccatgcgacg tgacggagga atgctgagtg gctgagataa 3390 0 aaacgctgca tctggtcccg cgtgaaggga tgcaggtgag tgagaagccg tcggtggtga 3396 0 gggtgcggtt tggtgacggt tatgaacagc gccgccccac agggctgaat cctcaactga 3402 0 agacgtttca ggcggtgttc cgggtgacgg atgagtcaac ccggcgctgg ctggatgaat 3408 0 ttttatcctg gcatggtggt taccgtgcct ttttgtggcg accgccgaaa cataaccgga 3414 0 cggtgagggg tgtgtgccgg gagtggagcg tcacggataa cgcccggtac agtgatttca 3420 0 gttgcacgat agagcaggtg gtgaactgat gcagaatatt catgaagaaa gcctgaacga 3426 0 gtcggttaag tcagagcagt caccgcgggt ggtgctctgg gaaatcgacc tgacggtgca 3432 0 gggcggtgag cggtattttt tctgtaatga gctgaatgaa aaaggggagg cggtcacctg 3438 0 gcaggggcgg caatatcagg tatacccgat tgacggcagt ggctttgaga tgaacgggaa 3444 0 gggcagcagt gcccgcccgt cgctgacggt gtcgaatctg ttcggtctgg tcaccggaat 3450 0 ggcggaggac ctgcagagcc tggtgggggc cacggtggtc cgccgccggg tgtatgcccg 3456 0 ttttctggat gcggtgaatt ttgtggcggg caatccggaa gcggacccgg agcaggagct 3462 0 gagagaccgc tgggtggtgg agcagatgtc agagctgacg gccatgacag cctcgtttgt 3468 0 gctggcaaca ccgacggaga cggacggagc gctgtttccc ggtcgcatca tgctggcgaa 3474 0 cacctgtatg tgggattacc ggggagatga atgcggttat cacggtcctg cggtggcgga 3480 0 tgagttcgac aaccccacca cggatatccg taaggacaga tgcagcaagt gcatgcgcgg 3486 0 gtgtgagatg cgcggcatgg tggctaattt tggcggtttc ctttccatta ataaactttc 3492 0 gcagtaatgg attatgccca ccatcaggtg ggttttttat cttcgccgta catgctgctg 3498 0 agagtcttaa gaagagcctc cctaaatttt tcagattctt gttgagcaaa accttctatt 3504 0 gatcttggtg atttttcttc atcaatagca gcttgcaaga tcataactat ttctgaattt 3510 0 aatgagcgtc cgtttttcga tgctcttatg gtcaggtcgc gcttgaggct atctggcatt 3516 0 cttacgctat atggggctat gtctctaacc ttcgtcatac ttacaccgtg ataatcacat 3522 0 tgatatcaca gtgtattcaa aaaaactttg acttgatata gtcacagtga tacgtttgtg 3528 0 attcataata actcacgcgg tggcgatatg gaaaaagaag ttagcagaat tttggtgaga 3534 0 atacctcagt cgctaaaaga tgcgattaca ggaaaggcca aagaagaatg ccggtcgttt 3540 0 aactcggaag tgatgtgatt gctggacagc ctgaagagag aggggataac ggtatgagta 3546 0 aagaatgttg ttttttgcgg cattagcgaa tcagacgctg atcaaacata catttactct 3552 0 aaagaaacag gtcggatgct gtgtagtgac tgcgtgtttg acatcataag atacaagtat 3558 0 cttggatgtt ctgccagcat tagcaatata ggtgaagtgt acgaagggaa agatataact 3564 0 gatagagcag aaagttgaag ccccaactgc tgtaacagtc agggcttcgt tatcaacaaa 3570 0 tcggcttagg aaatattgac atgaaaagta tagcaaaggc acaaaacgat ttcactatct 3576 0 tcaaattcgg cgacagtgaa atccgcgtca tcaacaagtg cggtgagccg tggtttgtag 3582 0 ctaaagatgt ttgtgatgct ttagctttga ctaactcacg caaggcgctt actgcacttg 3588 0 atgacgatga aaagggagta actttaagtt acacccttgg tggtgagcag aatctaagca 3594 0 ttgtgagcga atcaggtatg tatacattgg ttctgcgctg ccgcgatgca gtcaataaag 3600 0 gttcagtccc gcacaaattc cgcaagtggg taacagcaga agttctgcct tcaattcgca 3606 0 aacatggcga gtatgtaaaa ggaaagaaaa ccactgttga ggaaagaaca ccgctacgcg 3612 0 atgcagtaaa catgctggta ggaaagaaag gacttcgcaa tgacgatgca tacaatatgg 3618 0 ttcatcagcg ttttggtatt gacagcattg atgagctttc aattgaacaa atcccgcttg 3624 0 ccgtagagta catccacagg gtagtgcttg aaggtgaatt cattggcaaa caagagaaga 3630 0 gcaccaacga gctttccgca aaagaagcaa acagccttgt atggctatgg gattatgcca 3636 0 accgctcaca ggcattattc cgcgaactgt atccggcgct aaaacaaatt caatcgaact 3642 0 attccggcag atgctacgac tacggtcatg agttctcgta tgttattgga atggcgagag 3648 0 acgttttaat taatcacaca cgagatgttg atatcaatga gccagacgga ccaacgaatc 3654 0 tttccgcatg gatgagactt aagaataaag aattacctcc ttcaccgcat cactactaac 3660 0 agattgccaa cgaaatgacc cagcttcggc tgggttttta tcaggagttc tcatgctcta 3666 0 tagcaatata ttggcgcacg cccggcgatg tgcaccagcg gagtcgtgcg gcttcgtggt 3672 0 gagaacgccg gaaggggaaa gatattttcc ctgcgtgaat atctccggtg agccggaaga 3678 0 ttatttccgg atgtcgccgg aggactggct gcgggcagaa atgcaggggg agattgtggc 3684 0 actggtccac agccaccccg gtggtctgcc ctggctgagc gaggccgacc ggcggctgca 3690 0 gataaaaagt gcactgtcct ggtggctggt ctgccggggg gaaattcata aattccgctg 3696 0 tgtgccacat ctgacaggac ggcgctttga gcacggggtg acggactgtt acacgctgtt 3702 0 ccgggatgcc taccatctgg cgggaattga tatgccggat tttgagcgtg aggatgactg 3708 0 gtggcgcaac ggtcagaacc tttacctgga caatatggcg gtcaccggct tttaccgggt 3714 0 gcccctgtcc tctgcacagg cgggcgatat cctgctgtgc tgctttggcg catcggtggc 3720 0 caatcatgcc gccatatact gcggcaacgg tgaactgctt caccatctgc ctgaacaact 3726 0 gagtaaacgg gagaggtatt ccgaaaaatg gcaacgacga acgcattcag cctggcgtca 3732 0 ccgccactgg cacgtatctg ccttcacggg gatttacaac gatttggccg ccgcctcagc 3738 0 ctgtacgtga acacggcagc ggaagccatc cgtgccctgt cgctgcagat gccgggattc 3744 0 cgccgtcaga tgaacgaagg ctggtaccag acacgtattc cgacagcttc acaaaaccgg 3750 0 agtccggctc cggtttttgt tgtcatgtcc ggggaatatt tgttagataa aaaagaggag 3756 0 ataattcaat agggagttaa attaatgccg ataaatctga catcttattt gtgggtacag 3762 0 ggacagaaag ttgtcccggc agttgtgttt tctaatttta ctttagtgga ctaagtaaaa 3768 0 aggagtgaga taaatgctgc ccactacaaa tatctctgta aattctggag taatatcttt 3774 0 tgaaagtcct gtagattcac catctaacga ggatgttgaa gttgccctcg aaaagtggtg 3780 0 tgctgaggga gaatttagcg aaaatcgtca tgaggttgca tcaaaaatac ttgatgttat 3786 0 aagtactaat ggagagactt tatcaatcag tgagccaata acaacattac cagacttgct 3792 0 tccaggttct ctgaaagaac tggttttgaa tggatgtaca gagcttaaat caataaactg 3798 0 cttacccccc aacttatctt cattaagtat ggttggatgc tcatcattag aggttataaa 3804 0 ttgcagcata cctgaaaatg tcattaattt atctttatgc cattgtagtt ctttgaaaca 3810 0 tatagaaggt tcctttcctg aggcactcag aaattccgta tatttaaatg gctgtaattc 3816 0 attaaatgaa tcgcaatgtc aattccttgc atatgatgtc agtcaaggcc gtgcctgcct 3822 0 gagcaaagct gagcttactg ctgacttaat ttggttgtca gctaaccgaa cgggtgaaga 3828 0 gtctgctgaa gaattgaatt actctggatg tgacttgtca ggtctaagtc ttgtagggct 3834 0 gaatttatca tcagtaaatt tttctggagc agtgcttgat gatacagatc tcaggatgag 3840 0 tgatttgtct caggctgtat tggaaaactg ttcttttaaa aactcgattt tgaatgaatg 3846 0 taatttttgt tatgctaatt tatctaattg tattattagg gctttgtttg aaaactctaa 3852 0 tttcagcaat tccaatctta aaaatgcatc atttaaagga tcttcatata tacaatatcc 3858 0 tccaattttg aacgaggctg atttaacagg agctattata attcctggaa tggttttaag 3864 0 tggtgctatc ttaggtgatg taaaggagct ctttagtgaa aaaagtaata ccattaatct 3870 0 aggagggtgt tacatagatc tatctgacat acaggaaaat atattatctg tgttggataa 3876 0 ctatacaaaa tcaaataaat caattttatt gactatgaat acatctgatg ataagtataa 3882 0 ccatgataaa gtaagggccg ctgaagaact tatcaaaaaa atatctcttg acgaattagc 3888 0 ggcgttccgg ccctatgtta agatgtcttt ggctgattca tttagtattc atccttattt 3894 0 gaacaacgca aatatacagc aatggctcga gcctatatgt gatgactttt ttgatactat 3900 0 aatgtcttgg tttaataatt caataatgat gtatatggag aatggtagtt tattgcaggc 3906 0 agggatgtat tttgagcgac atccaggtgc gatggtatct tataatagtt cctttataca 3912 0 aattgtaatg aatggttcac ggcgtgatgg aatgcaggaa cgatttaggg aactctatga 3918 0 agtatattta aaaaatgaaa aagtttatcc tgtcacacag cagagtgatt ttggattgtg 3924 0 cgatggctct gggaagcctg actgggatga tgattccgat ttggcttata actgggtttt 3930 0 gttatcatca caggatgatg gtatggcaat gatgtgttct ttgagtcata tggttgatat 3936 0 gttatctcct aatacatcaa ctaattggat gtcctttttt ttatataagg atggagaagt 3942 0 tcaaaataca tttgggtatt cattgagcaa tcttttttct gaatcatttc caattttcag 3948 0 tattccttat cataaagctt tttcccagaa tttcgtttct ggtattctgg atatactcat 3954 0 ttctgataat gaactcaaag agagatttat tgaggcactt aattccaata aatcagatta 3960 0 taaaatgatt gctgatgatc agcaaaggaa acttgcctgt gtctggaatc cctttcttga 3966 0 tggttgggaa ctgaacgctc agcatgtaga tatgattatg gggagccatg tattgaaaga 3972 0 tatgccacta agaaaacagg ctgaaatatt attttgttta gggggggttt tctgtaaata 3978 0 ctcatcgagt gatatgtttg gtacagagta tgattctcct gagattctac ggagatatgc 3984 0 aaatggattg attgaacaag cttataaaac agatcctcag gtatttggct cagtttatta 3990 0 ttacaatgat attttagaca ggctacaagg aagaaataat gtttttactt gtaccgctgt 3996 0 gctgactgat atgctaacgg agcatgcaaa agaatctttt cctgaaatat tttcattgta 4002 0 ttatcctgtt gcgtggcgtt gatttagaga ccatggatga atattattgt aacactgtct 4008 0 ttttaggttt gcacatgttc agtgggaaca tttattgctc cgttgttatt atgtcttggt 4014 0 ttagtggcat gagccgaatg ttcttaaaat ttacagtgtc gaagatgaaa gagtacgata 4020 0 gaactcgttg tgattcgatt tgtctgatat ggtggtaata tatgaatagg atactgcata 4026 0 tatcgtagtg cttgaggatg ttgattaggg catatgattt ttatattttt cttgagcaac 4032 0 gttttaaggg aaaatttaca tatgacaact ttgtctgaag agtatctttg ttgtcagtat 4038 0 ttttttgaat gtgataattg attttgtttt gctgtgaatg gtcactatag atgaaatatg 4044 0 attttaatta caacgaaaat tatgttcgtt atttctgggc aaatcgtgga gaatcatatt 4050 0 ttatgaattg atattcagat taatatgttt ttgttactat agtaatatgg cgtaattaat 4056 0 gattgttttg aaaagactct caactggtgt ttattcattg aatagtgcgt tataagagga 4062 0 agtggaattt taatgaaaat aacaaactat atactgccaa caagtcgtac tcatggttca 4068 0 ttctcaacta taaaatcatg ggacacaatg aattatatta aacatttaat cagacataca 4074 0 aatgacccta tatttgaaga acaattttat aaaataacac aatctcatat tgactttgac 4080 0 aaaagagcta aagatgaaaa aaatgacacc attaacattt atgataactt tttctattca 4086 0 tctaatgatg atcttgattc taaaattaga agtatgttaa ataatttata tgagaaaagc 4092 0 ttaactttcc gaagaataat taattattat gtgaaggaaa taaacttaag tgattatggc 4098 0 tttctaaaat gtaagatttt accagcatat gcttataact atgagatgga aaatgatgcc 4104 0 cccccaaaaa tactaattcc aattgaccat aatttaaatt ttattgatgc aaaatataat 4110 0 ggagaaactt atcggggaaa tgaagagttt gctattaatc tttttctgca gcatatatta 4116 0 cataatgaca tacaagaaca aacatcgata gacttataca cgagcataat aaataaagag 4122 0 ttggatagca atagaaaatc atacaataat gaaattttta acaatttctc ttttgataag 4128 0 tctgtaaagt tgaattcata taactatatt gcagatgata tagagcaagt aatcgataaa 4134 0 ggaagcaaag ttcaattgga ggtatataat ttattatccg aagaaaagat atttgaacat 4140 0 aaaattatga ataattggac aaggagcata aaaaatatat tgacgacata tttgtttatg 4146 0 tcatcaggag cggtgacagc cagaaatgtt caaacctttt ctccaacaat aaataatgag 4152 0 tcaaggattc gattgccgag agcattgcca gtaggccatc catatcctga ggaacataag 4158 0 gcttctggtt tctccccttt tatgatgggg gggctgagtg gtgatattct tccggaaatt 4164 0 ttaacgggga atggaccatc tatatttttt aacggaaaac ataataacca acatgatgga 4170 0 gcttttggaa aaataataga ttttacccaa aatggaaata aaataagtgc aaaagataaa 4176 0 gaaataataa aaagatatat ttttgataag atcaatgttt tgattaaaga gtatttcatt 4182 0 agaactggta aaaattctca taccccattt gaagttttta taaaggagcg attatttaat 4188 0 caatatgata tttttaaaac attggctaga gatatattgg cacacccatt agtaatatat 4194 0 gatgcgggtt acaaaaatta tcatgagtca ttaaatgctg ctattgcaat aaactctaga 4200 0 ccattacaag aaatacatta tggtgatgtt ttatatcatt atcataaaaa tgacatctct 4206 0 ttgggagtag atactcttta cgggagggaa agttttgata ttgtactgga tgcaatgaac 4212 0 gtatatagaa aaagcaaaaa aatgagagtt atttccaata atgagatgaa aaaaagcatt 4218 0 aaaatatctg aattagttat ccataatatt ataaagaaag gattgactaa ttgtttgctt 4224 0 aaaaaggatg ttcttaatgc cagatatgat cttattagag atattcttcg atattcttta 4230 0 aatatacgac agggaattaa acatgatgat gttaatagaa tagcggaaaa tataataaaa 4236 0 aagtatggta taactgaggg tatgaatcct aaacctagga atgccagaat atctaaagaa 4242 0 ttgcttttat tagctgttga tagacagatt gagtgggcga aaaaacattt tataacaaaa 4248 0 gatgtattgg aaaatgttgt gtcaaaatgt gatttatcat ctatctttaa tgttaataaa 4254 0 gtgcttcaga atactattct tgagtttgtc catgaaatta ataatatatc atctgctcgc 4260 0 tggatgtcaa aatcagaaaa gaataataaa caaaaagagg caatagaaaa gttcaaaaaa 4266 0 gaagtatccc atatgaatgg cgggcagcag tttatttggg ggtttgataa ggttattcaa 4272 0 gaaggcttaa gtggattgat tgagttaagt atcgatatta atgatagtac aaatcatcgt 4278 0 gataagtctt ctctttctcc tgatgggaga gctgtgttac attttttagg tacaatttgg 4284 0 aatatggcga tgggagctgt acctggttat aatgcattgt ctggtgtaag tagcatttta 4290 0 catagtgcta tagtaaaaga atctagcaat atctgtgatt atattcaggg ggctgtacgt 4296 0 attggaatgg actttgttcc aggcactcgc tctgacttac atagccgttc gctgcagata 4302 0 aaatatgagg ctttgaagca tatagaaaaa aacattaatg ataatattat ttatcatccg 4308 0 agtaataatg ctaatttcta ttctgtaatt gagtcaattg atggtaatga ctttatatat 4314 0 aacgaaaaac aatctaaaat attagaaatg aaacaggatc gtggggggaa tagatatagt 4320 0 gcagtagatc ttaactcttc taagtatggg tattatgaga aagttggcgg tggtttttat 4326 0 agatatatag aatcctttaa ccccatatct tcagagacac caaataaaat agtctacaag 4332 0 ggggaatcag tagatttaac taaggagcca aattcggaat tatattcagg taggtattct 4338 0 ataaataaca aacaggttaa tgtttatttc tttcgtgacg ctgatggtac attttataaa 4344 0 tcagaaggtc ttcatggtgg gggagttatt agatacatag ataaaccgta ttctcagtta 4350 0 agagaaggag atattgggta tgatgaggat ttgttggata tatacgatga ttctccggtg 4356 0 cttgaagaca cgttgcctgc tttatcttct gaaatagtac caactccaga acatagtatt 4362 0 aaacaaattt attcgaaaat taaggagggg cacatagaac tgtccgattc agacatcata 4368 0 ttgtgtcgcg gcacaaccgg tattcaagct gaaaatatcg ttgaatataa aactgctgga 4374 0 gggcttcctg attcaaatcc aaatgtaaaa gcaccagatg aatatatggc acaacagcag 4380 0 gtacgtattg gaagaatatt gcctgaatac acatcggatc ttagcgttgc tgatcggttt 4386 0 agtcgtgagc attatctaat agttgttaaa gtaaaggcaa aatatatcac acgaggaagt 4392 0 gttacagaga gtggttgggt tatagataag accgcacctg ttgaaccact tgcgataatt 4398 0 gatagaactt ttggtatgaa ggaaaatatc tcaatggtaa atgcatcgaa atagtttttt 4404 0 tacaatctat gtcctgcctc ctctggtaaa aacgatgcta catcttggag atgttgcacg 4410 0 gcagtacggt gttgaccgat atgtagtgaa gtacacatcg gtcaacgaat taccattgtc 4416 0 agcaatatca tcctgataaa ctcagtactc gtgagccgct tgatgacggg cggaatagcc 4422 0 caaaaggtaa acgatccgca tggcagtccg tcggaaagct gctgcttcat acgaccgctt 4428 0 aaaccgtcag ttagtgtcag tatcgctgaa gatcagcttc ttttgctgat ttactctgtt 4434 0 tttacctgcc ctgatgaaat actctttaat cataacattg attatatcga aaatatattt 4440 0 tttgctatca ttaagaatat ttatatgtgg aaccggagta ttttggacgg tagtctttcc 4446 0 actctggtgt atctaatatt ctttctgctg gtatctcttt gccatgcaga taaaatttta 4452 0 tgtttttcat tatttggctg ttgtctttat tacgataaat ccatctggat ttgcccctat 4458 0 atttccagac atctgttatc acttaaccca ttacaagccc gctgccgcag atattcccgt 4464 0 ggcgagcgat aacccagcgc actatgcgga tgccattcgt tataatgctc gaacgcctct 4470 0 gcaaggttct ttgctgccgt taacccgtct ggtttgggca tgatactgat gtagtcacgc 4476 0 tttatcgttt tcacgaagtt ctctgctatt ccgttactct ccggactccg caccgccgtg 4482 0 ttcttcggtt caagtcccaa catccgggcg aactggcgtg tttcattagc ccggtagcat 4488 0 gaaccattat ccgtcagcca ctccactgga gacgacggaa gatcgttgcc gaagcggcgt 4494 0 tccaccgctc ccagcatgac gtcctgtact gtttcactgt tgaagccgcc ggtagtcacc 4500 0 gcccagtgca gtgcctcacg atcacagcag tccagcgcga acgtgacacg cagtctctct 4506 0 ccgttatcac agcagaactc gaacccgtca gagcaccatc gctgattgct ttctttcacg 4512 0 gccactctgc ctgtatgtgc ccgtttcgat ggcggtacag taggttttcg ctcaagcaac 4518 0 agcgcattct ggcgcatgat ccggtaaaca cgtttggcat tgatcgcagg cataccatca 4524 0 agttctgcct gtctgcgaag cagcgcccat acccgacgat aaccatacgt gggcagctct 4530 0 ccgataacat ggtgtatacg gagaagcaca tccgtatcat cagtgtgacg actgcggcgg 4536 0 ccatccatcc agtcatcggt tcgtctgaga atgacgtaca actgcgcacg cgacacccgg 4542 0 agacaacggc tgactaagct tactccccat ccccgggcaa taagggcgcg tgcgctatcc 4548 0 acttttttgc ccgtccatat tcaacggctt ctttgaggag ttcattttcc atcgttttct 4554 0 tgccgagcag gcgctggagt tctttaatct gcttcatggc ggcagcaagt tcagaggcag 4560 0 gaacaacctg ttctccggcg gcgacagcag taagacttcc ttcctagtat tgcttacgcc 4566 0 agagaaataa ctggctggct gctacaccat gttgccgggc aacgagggag accgtcatcc 4572 0 ccggttcaaa gctctgctga acaattgcga tcttttcctg tgtggtacgc cgtctgcgtt 4578 0 tctccggccc taagacatca atcatctgtt ctccaatgac tagtctaaaa actagtatta 4584 0 agactatcac ttatttaagt gatactggtt gtctggagat tcagggggcc agtctagtca 4590 0 tctacacaac caacgccatc gagtcgctga acagcgtaat ccggcatgcc atcaaaaaac 4596 0 gcaaggtgtt cccgacggat gactcagtga aaaaggtcgt gtggctggca atccaggcgg 4602 0 cttcacagaa atggacgatg ccactgcggg actggcgtat ggcaatgagc cgctttatta 4608 0 tcgagttcgg tgaccgcctg gacggtcact tctgagaaaa ggcatttaca cagaatcgtg 4614 0 tacagggtca aatattttaa ttttactaca ttgcatgatt acaatcattt ttgtgacttt 4620 0 attgagttta aacacaaaaa tattattatg aacacaagtc agtacacagg aagttcatgg 4626 0 taaaaccacc tcctgtggag gtggttgctt gcagtcaggt gtttcgggtc tgtggctttt 4632 0 tgtgttctct ggtaagtggt tgctattctt ttgtgttgtg tatctctgtt tctatagttt 4638 0 tagatagcca tgtcatctca gtaactgaga gttttagttt tggggttctt tctcctgcgc 4644 0 cgggtgggcg catgtcaaaa ctacaggctt ttttttggta cactgtatag ctatctacat 4650 0 tacatgttgt tgatgtaagt atgcagttct ttgacgctgg cttgtctttt atgggaccgg 4656 0 atatttccgg gtaatgtact tgtgaacttg aaaatctgtt tttgattgaa aatggcattg 4662 0 ttttctcctt tgctccatga aaagtgtttt tatgctattc cgttataagt tggtatcatt 4668 0 aagaatattt atatgtggaa ccagagtatt ttggacgata gtctttccat tctggtgtat 4674 0 ctaatattct ttctgctggt atctctttgc catgtagata aaattttatg tttttcatta 4680 0 tttggttgtt gtctttatta cggtaaatcc atcgtaattc gctggcggta atactctggc 4686 0 catagccctc tgacttgtta gctatgagtt tgagtgagtt gacaagctca tccgcacaaa 4692 0 aaataaccgt tttattgcgt gttaatgtct gaaactctag gccggccttg cttgtttttg 4698 0 cccataattt gtcgcgattg tatacggaaa ggtcggccat ggtaacatta taattattgt 4704 0 gattctttaa gtgttgttta aattttattc ctctttcgtg ttcatttaat gctcttttga 4710 0 taagtggatc ttgcttatat ttgcgaggtg ttctggggtc ccatactgcg tttgttaacg 4716 0 tattctgagt tataatatct tttttggaaa agtcgttaac tagtttaatg ctgttgacaa 4722 0 gtttttctct gggtgaagat agtccataga caatgtctcc ctcgcgaaag tgtaaggcca 4728 0 catccagagc gttgccctga aaggtgatgt tttttgcttt aactacatct ggagagagta 4734 0 gtacattttg taaatcaaga tccagcccat caggcatccc ttcaacaccg atgttccacg 4740 0 tggttttctg ctccgcatga atggttaccg atgtcacact ctccggaagt ttctccggca 4746 0 gtataatatt gctacatcca gtcagcgata gcgtcttcag tgacggtgat atcaggttgt 4752 0 caattctggc ctgattctcc gggttatagc tattgatgct gagagatgat aacccgtttg 4758 0 gaacattttt tatgctgtct gtggcgctac cttttatttc aaggtagcgg acactctctg 4764 0 gcactccaga tatatagcag tggcaaaccg tcaggcactc gatgccttca gatatgaaat 4770 0 gtataaatgg tgaatcagtt aattcaatat gtagattttt tacggttgat ggcatgtctg 4776 0 tgatttgtaa tttttcacag ttaatgacgg agaggttttg tgtattaacc ggcaatcctg 4782 0 taagggttgt caggttgttg cagttttcga ttgtaactga tgttatttcg tttggtaact 4788 0 gtggcagata ctcaatatca caatctttga tatataaacg accactggcc cgcgcttctt 4794 0 ctatctgaat tggtgtgatt tcgcttttga tgtctgctga tgtttcagcg gaataggagc 4800 0 agaatgtccc ggtcggtcgt aattgcgatg taggaagcat tgataaattc catttttaga 4806 0 aataaataac agagtaagtt ctatccatac tactaatcaa caagctaatt ttaacaacca 4812 0 gcaaagccaa ggtgtcaata ttagaaaaga gagttatatc tcaaaaccaa cagactgttg 4818 0 attttaactt ttgcgaatac tttctccagt ccgtcatgca tggattagga ttgctcattt 4824 0 ttataccatt tgttgttttt ttatagcgat ttgctaaaag ggagaagaaa aaacgttctc 4830 0 caaaattaga ttgcaactgt ttgattttat ggatagaggc atgctgttta ctagacagta 4836 0 aaaagcatgc caaatttcct attaaccttt tgaatataaa gcactaatta tctatttctg 4842 0 ttg 4842 3 <210> 485 <211> 373 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(157..1275) <400> 485 Met Ser Pro Arg Pro Arg Lys Asn Ser Thr Asp Val Ala Gly Leu Tyr 1 5 10 15 Glu Lys Phe Asp Arg Arg Thr Gly Arg Val Tyr Tyr Gln Tyr Lys Asn 20 25 30 Pro Val Thr Gly Lys Phe His Gly Leu Gly Thr Asp Lys Gly Lys Ala 35 40 45 Glu Lys Ile Ala Ser Thr Ala Asn Gln Arg Ile Ala Ala Ala Glu Ala 50 55 60 Glu Tyr Phe Met Arg Lys Ile Asp Glu Ser Pro Ser Ala Thr Lys Arg 65 70 75 80 Arg Gly Ile Arg Leu Lys Ala Trp Val Asp Arg Tyr Leu Lys Ile Gln 85 90 95 Asp Thr Arg Leu Lys Asn Gly Asp Ile Ala Ala Thr Thr His Lys Glu 100 105 110 Lys Thr Arg Met Ala Ala Tyr Leu Val Ser Arg Leu Gly Asn His Pro 115 120 125 Leu Lys Glu Leu Glu Val Arg Asp Phe Ala Leu Ile Leu Asp Glu Trp 130 135 140 Leu Asp Lys Asp Met Val Ser Thr Ala Arg Val Asn Arg Gly Leu Trp 145 150 155 160 Val Asp Ile Tyr Lys Glu Ala Gln His Ala Gly Glu Val Pro Pro Gly 165 170 175 Trp Asn Pro Pro Glu Ala Thr Arg Lys Pro Ile Pro Lys Val Thr Arg 180 185 190 Ala Arg Leu Thr Met Glu Asp Trp Gln Lys Ile Tyr Asn Ala Thr Pro 195 200 205 Glu Lys His Phe Ile Arg Asn Ala Met Leu Leu Ala Ile Val Thr Gly 210 215 220 Gln Arg Arg Asp Asp Ile Cys His Met Arg Phe Ser Asp Val Trp Asn 225 230 235 240 Glu His Leu His Ile Thr Gln Gly Lys Thr Gly Met Arg Leu Ala Leu 245 250 255 Pro Leu Thr Leu Arg Cys Asp Ala Ile Gly Ile Thr Leu Lys Glu Val 260 265 270 Ile Asp Gly Cys Arg Asp Arg Ile Leu Ser Pro Tyr Leu Ile His Ser 275 280 285 Arg His Gln Lys Gln Pro Lys Pro Met Ser Lys Asp Asn Leu Ser Asp 290 295 300 Tyr Phe Ala Lys Ala Arg Asp Leu Ala Gly Val Ile Pro Pro Ala Gly 305 310 315 320 Lys Thr Pro Pro Thr Phe His Glu Gln Arg Ser Leu Ser Glu Arg Leu 325 330 335 Tyr Arg Ala Gln Gly Ile Asp Thr Lys Thr Leu Leu Gly His Lys Val 340 345 350 Gln Ala Thr Thr Asp Arg Tyr Asn Asp Thr Arg Gly Gln Glu Trp Val 355 360 365 Lys Leu Val Ile * 370 <210> 486 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1244..1513) <400> 486 Met Ser Glu Gln Tyr Leu Ile Thr Leu Asp Glu Trp Lys Pro Lys Arg 1 5 10 15 Phe Ser Leu Pro Ile Thr Asn Thr Thr Leu Val Lys Tyr Gly Lys Leu 20 25 30 Gly Tyr Ile Val Pro Arg Pro Gln Lys Ile Arg Gly Arg Trp Leu Ile 35 40 45 Asp Arg Arg Ala Val Phe Val Gly Pro Gly Glu Thr Gly Ile Ala Pro 50 55 60 Glu Ile His Thr Gly Asp Asp Asp Ala Leu Lys Glu Ile Leu Thr His 65 70 75 80 Val Thr Glu Ala Thr Lys Lys Gln His * 85 <210> 487 <211> 146 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1575..2012) <400> 487 Val Val Lys Ser Arg His Thr Thr Arg Lys His Thr Ala Arg Asp Thr 1 5 10 15 Ile Lys Trp Trp Leu Lys Gln Ser Arg Glu Ala Gln Ser Ala Ile Met 20 25 30 Thr Asp Glu Ile Pro Leu Asp Asp Ala Leu Leu Gln Leu Arg Glu Phe 35 40 45 Ile Asp Glu Asn Ser Gly Glu Phe Phe Val Gln Val Trp Gly Asn Gly 50 55 60 Ala Asn Phe Asp Asn Thr Ile Leu Arg Arg Ser Tyr Glu Arg Gln Gly 65 70 75 80 Ile Pro Cys Pro Trp Arg Tyr Tyr Asn Asp Arg Asp Val Arg Thr Ile 85 90 95 Val Glu Leu Gly Lys Ala Ile Asp Phe Asp Ala Arg Thr Ala Ile Pro 100 105 110 Phe Glu Gly Glu Arg His Asn Ala Leu Asp Asp Ala Arg Tyr Gln Ala 115 120 125 Lys Tyr Val Ser Val Ile Trp Gln Lys Leu Ile Pro Ser Gln Ala Asp 130 135 140 Phe * 145 <210> 488 <211> 186 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2055..2612) <400> 488 Leu Leu Ile Trp Ile Ser Pro Thr Thr Ile Arg Val Leu Asn Val Ile 1 5 10 15 Ala Glu Leu Thr Ala Ala Met Thr Ala Ile Arg Glu Thr Ala Gln Ile 20 25 30 Ala Lys Leu Met Asn Glu Ala Lys Thr Gln Ala Glu Val Asn Ala Ala 35 40 45 Ile Gly Glu Leu Asn Ser Lys Leu Ala Ser Ile Gln Arg Glu Cys Val 50 55 60 Ser Leu Val Glu Leu Val Gly Thr Tyr Gln Glu Ile Asn Ala Ser Leu 65 70 75 80 Lys Ala Lys Ile Ala Glu Phe Glu Asn Phe Glu Ala Gln Thr Glu Gly 85 90 95 Tyr Ile Leu Ser Gln Leu Glu Ser Gly Thr Phe Val Tyr Ser Lys Glu 100 105 110 Val Thr Val Asn Gly Gly Ser Ile Ile Met His Leu Cys Pro Lys Cys 115 120 125 Phe Gly Gln Lys Ile Val Ser Ile Leu Gln Pro Phe Pro Val Arg Glu 130 135 140 Tyr Glu Phe Phe His Lys Ser Arg Cys Leu Tyr Cys Glu Asn Gln Phe 145 150 155 160 Leu Met Asn Lys Asn Pro Asp Tyr Val Ser Pro Pro Ser Ile Glu Glu 165 170 175 Leu Ala Arg Lys Leu Asn Gly Asn Leu * 180 185 <210> 489 <211> 77 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2727..2957) <400> 489 Met Thr Ala Gly Phe Asn Phe Asn Tyr Ala Ala Gly Phe Cys Ser Ala 1 5 10 15 Thr Pro Ala Leu Arg Gly Tyr Glu Val Ser Met Asp Thr Leu Asp Leu 20 25 30 Gly Asn Asn Glu Ser Leu Val Cys Gly Val Phe Pro Asn Gln Asp Gly 35 40 45 Thr Phe Thr Ala Met Thr Tyr Thr Lys Ser Lys Thr Phe Lys Thr Glu 50 55 60 Ser Gly Ala Arg Arg Trp Leu Ala Arg Asn Ser Asp * 65 70 75 <210> 490 <211> 159 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3195..3671) <400> 490 Met Leu Ser Gly Lys Asp Leu Gly Arg Ala Ile Glu Gln Ala Ile Asn 1 5 10 15 Lys Lys Ile Ala Ser Gly Ala Val Lys Ser Lys Ala Glu Ile Ala Arg 20 25 30 His Phe Lys Val Gln Pro Pro Ser Ile His Asp Trp Ile Lys Lys Gly 35 40 45 Ser Ile Ser Lys Asp Lys Leu Pro Glu Leu Trp Arg Phe Phe Ser Asp 50 55 60 Val Val Gly Pro Glu His Trp Gly Leu Asn Glu Tyr Pro Ile Pro Thr 65 70 75 80 Pro Ser Thr Ser Asp Thr Lys Ser Glu Leu Leu Asp Ile Asn Ser Leu 85 90 95 Tyr Gln Ala Ala Ser Asp Glu Lys Arg Ala Ile Val Ala Phe Leu Leu 100 105 110 Ser Gly Asn Ala Thr Glu Pro Ser Trp Val Asp His Asp Val Arg Ala 115 120 125 Tyr Ile Ala Ala Met Glu Met Lys Val Ala Asn Tyr Leu Lys Asn Gln 130 135 140 Glu Ser Lys Arg Lys Ser Gln Asn Ile Thr Lys Thr Gly Thr * 145 150 155 <210> 491 <211> 108 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3796..4119) <400> 491 Met Lys Lys Asp Asn Tyr Ser Phe Lys Arg Ala Cys Ala Val Val Gly 1 5 10 15 Gly Gln Ser Ala Met Ala Arg Leu Leu Gly Val Ser Pro Pro Ser Val 20 25 30 Asn Gln Trp Ile Lys Gly Val Arg Gln Leu Pro Ala Glu Arg Cys Pro 35 40 45 Ala Ile Glu Arg Ala Thr Lys Gly Gly Val Leu Cys Glu Glu Leu Arg 50 55 60 Pro Asp Val Asp Trp Thr Tyr Leu Arg Arg Ser Ser Cys Tyr Ser Gln 65 70 75 80 Asn Met Ser Met Lys Gln Pro Asn Asp Glu Asn Asp His Thr Arg Ser 85 90 95 Ile Lys Arg Gln Met Ile His Glu Asn Gln Thr * 100 105 <210> 492 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4103..4528) <400> 492 Met Lys Ile Lys His Glu His Ile Arg Met Ala Met Asn Ala Trp Ala 1 5 10 15 Tyr Pro Asp Gly Glu Lys Val Pro Ala Ala Glu Ile Ala Arg Thr Tyr 20 25 30 Phe Glu Leu Gly Met Thr Phe Pro Glu Leu Tyr Asp Asp Ser His Pro 35 40 45 Glu Ala Leu Ala Arg Asn Thr Gln Lys Ile Phe Arg Trp Leu Asp Lys 50 55 60 Asp Thr Pro Asp Ala Val Glu Lys Met Gln Ala Leu Leu Pro Ala Ile 65 70 75 80 Glu Lys Ala Met Pro Pro Leu Leu Val Ala Arg Met Arg Ser His Ser 85 90 95 Ser Glu Tyr Tyr Arg Glu Ile Val Glu Arg Arg Asp Arg Leu Val Lys 100 105 110 Asp Val Asp Asp Phe Val Ala Ala Ala Ile Ala Trp Gly Thr Leu Thr 115 120 125 Asn Ser Gly Gly Gln Pro Gly Asn Ala Val Val Val His * 130 135 140 <210> 493 <211> 346 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4597..5634) <400> 493 Met Ala Asn Ala Trp Leu Arg Leu Trp His Asp Met Pro Asn Asp Pro 1 5 10 15 Lys Trp Arg Thr Ile Ala Arg Val Ser Gly Gln Pro Ile Ala Thr Val 20 25 30 Met Ala Val Tyr Ile His Leu Leu Val Ser Ala Ser Arg Asn Val Thr 35 40 45 Lys Cys His Gly Glu Ser Leu Arg Gly His Ile Asp Val Thr Thr Glu 50 55 60 Asp Leu Ala Ser Ala Leu Asp Val Thr Glu Asp Val Ile Asp Ser Ile 65 70 75 80 Leu His Ala Met Gln Gly Arg Val Leu Asp Gly Asp Leu Ile Ser Gly 85 90 95 Trp Glu Lys Arg Gln Val Met Lys Glu Asp Asn Gly Asn Val Ser Gln 100 105 110 Thr Ala Lys Ser Pro Ala Glu Arg Lys Arg Ala Gln Arg Glu Arg Glu 115 120 125 Arg Leu Arg Glu Gln Asn Thr Asp Cys His Asp Glu Ser Arg Arg Val 130 135 140 Thr His Met Ser Arg Gln Val Thr Thr Asp Thr Asp Thr Asp Lys Glu 145 150 155 160 Leu Asn Pro Thr His Asn Ala Arg Met Arg Glu Ser Ala Pro Ala Ser 165 170 175 Glu Ser Asn Gly Ala Pro Leu Gln Thr Ala Glu Pro Glu Tyr Pro Asp 180 185 190 Gly Leu Ser Glu Pro Ile Gly Lys Phe Pro Met Thr Gly Val Trp Arg 195 200 205 Pro Ser Leu Asp Phe Arg Gln Arg Ala Ala Leu Trp Gly Met Ala Leu 210 215 220 Pro Glu Pro Glu Phe Thr Pro Ala Glu Leu Ala Ala Phe Arg Asp Tyr 225 230 235 240 Trp Met Ala Glu Gly Lys Val Phe Thr Gln Val Gln Trp Glu Gln Lys 245 250 255 Phe Ala Arg His Val Gln His Val Arg Ala Gln Val Lys Pro Val Ser 260 265 270 Lys Gly Val Ser His Ala Ala Pro Gly Gly Thr Ala Ser Arg Ala Val 275 280 285 Gln Glu Ile Arg Ala Ala Arg Glu Gln Trp Glu Arg Glu Asn Gly Phe 290 295 300 Ile Ser Asn Gly Asn Gly Leu Glu Ala Val Gly Thr Tyr Gly Gly Gly 305 310 315 320 Val Phe Glu Pro Leu Asp Pro Glu Glu Arg Gly Cys Ala Val Glu Ala 325 330 335 Leu Asp Cys Ser Asp Trp Arg Asp Asp * 340 345 <210> 494 <211> 198 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5495..6088) <400> 494 Val Lys Thr Asp Leu Ser Ala Thr Glu Thr Ala Trp Lys Leu Trp Glu 1 5 10 15 Leu Met Gly Glu Val Tyr Ser Asn Arg Trp Thr Gln Lys Asn Gly Ala 20 25 30 Ala Pro Ser Lys Leu Trp Ile Ala Gln Ile Gly Ala Met Thr Glu Gln 35 40 45 Gln Ile Arg Gln Val Cys Arg Gln Cys Met Asp Arg Cys Arg Ala Gly 50 55 60 Glu Thr Trp Pro Pro Asp Leu Ala Glu Phe Val Ala Leu Ile Ser Glu 65 70 75 80 Ser Gly Ala Asn Pro Phe Gly Leu Thr Val Asp Ala Val Met Glu Glu 85 90 95 Tyr Arg Arg Trp Arg Asn Glu Ser Trp Arg Tyr Asp Gly Ser Asp Lys 100 105 110 Tyr Pro Trp Pro Gln Pro Val Leu Tyr His Ile Cys Leu Glu Met Arg 115 120 125 Asp Arg Gly Ile Glu Arg Gln Met Thr Glu Gly Glu Leu Lys Arg Leu 130 135 140 Ala Glu Arg Gln Leu Thr Lys Trp Ala Lys Gln Val Gly Asn Gly Met 145 150 155 160 Ser Ile Pro Pro Ile Arg Arg Gln Leu Ala Ser Pro Lys Cys Pro Gln 165 170 175 Gly Pro Thr Pro Ile Glu Leu Leu Lys Gln Glu Tyr Glu Arg Arg Lys 180 185 190 Ala Ala Gly Phe Val * 195 <210> 495 <211> 239 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6122..6838) <400> 495 Met Glu Thr Val Ser Asp Ala Leu Lys Ala Leu Lys Arg Ala Ser Ser 1 5 10 15 His Val Val Ala Ala Arg Leu Gly Ile Ser Arg Glu Glu Ala Val Asn 20 25 30 Glu Leu Trp Lys Leu Lys Arg Arg Gly Glu Ala Asp Asn Lys Gly Ala 35 40 45 Ile Trp Trp Leu Thr Gln Ala Gly Glu Ser Glu Pro Val Ser Pro Val 50 55 60 Pro Lys Val Thr Ala Gln Met Leu Thr Glu Ala Ile Glu Gln His Gly 65 70 75 80 Pro Gln Thr Ala Asp Glu Leu Ala Leu Met Phe Gly Ile Thr Ser Arg 85 90 95 Arg Ala Asn Ser Ser Leu Ala Met Ala Ile Ser Lys Gly Cys Leu Ile 100 105 110 Arg Val Asn Gln Asp Gly Lys Phe Arg Tyr Cys Ile Pro Gly Val Asp 115 120 125 Leu Pro Ala Glu Pro Lys Ala Ala Ser Val Ala Glu Thr Glu Gly Lys 130 135 140 Ala Leu Pro Gln Pro Ala Gly Val Ala Leu Pro Val Gln Glu Thr Ala 145 150 155 160 Ala Gln Glu Glu Ile Lys Thr Glu Ala Val Glu Asp Ile Val Lys Leu 165 170 175 Gln Gln Ser Phe Thr Glu Ala Lys Ala Asp Asp Leu Ile Leu Pro Ser 180 185 190 Leu His Val Ala Asn Arg Glu Leu Arg Arg Ala Lys Ser Asn Val Gln 195 200 205 Lys Trp Glu Arg Val Cys Ala Ala Leu Arg Glu Leu Asn Lys His Arg 210 215 220 Asp Ile Leu Arg Asp Ile Thr Ala Thr Arg Glu Gln Gln Arg * 225 230 235 <210> 496 <211> 106 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6835..7152) <400> 496 Val Ser Gly Trp Lys Lys Trp Arg Trp Ala Glu Ile Leu Ile Leu Arg 1 5 10 15 Gln Cys Ala Gly Thr Met Arg Val Glu Ser Ile Gly Tyr Leu Ile Gly 20 25 30 Arg Ser Glu Ser Ala Val Arg Thr Lys Ala Arg Glu Leu Gly Ile Ser 35 40 45 Met Met Leu Arg Gly Asp Tyr His Gln Ser Ala Lys Cys Ser Gln Arg 50 55 60 Asp Ile Glu Leu Ala Trp Gln Leu His Gln Arg Gly Val Pro Arg Arg 65 70 75 80 Glu Ile Ala Glu Lys Phe Gly Met Lys Leu Gly Ala Val Asn Asn Tyr 85 90 95 Val Tyr Phe Asp Arg Arg Val Gln Glu * 100 105 <210> 497 <211> 101 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7149..7451) <400> 497 Val Arg Val Arg Val Tyr Ile Ala Gly Pro Met Thr Gly Tyr Glu Asn 1 5 10 15 Phe Asn Arg Glu Ala Phe His Lys Thr Glu Glu Val Leu Lys Arg Glu 20 25 30 Gly His Thr Val Leu Asn Pro Ala Val Leu Pro Asp Gly Leu Thr Gln 35 40 45 Pro His Tyr Met Asp Ile Cys Met Ala Met Leu Arg Cys Val Asp Ala 50 55 60 Val Tyr Met Leu Lys Gly Trp Gln Gln Ser Ala Gly Ala Gly Ala Glu 65 70 75 80 Leu Ala Leu Glu Glu Lys Pro Gly His Ala Val Ile Phe Gln Glu Val 85 90 95 Gly Ser Glu Tyr * 100 <210> 498 <211> 106 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7441..7758) <400> 498 Val Asn Ile Asp Pro Ala Ile Thr Ile Asp Met Ala Leu Asn Ala Gly 1 5 10 15 Leu Ala Leu Leu Gly Tyr Phe Tyr Ile Met Phe Cys Ser Gly Arg Trp 20 25 30 Leu Ser Leu Leu Phe Met Lys Lys Trp Asn Lys Arg Arg Lys Gln Glu 35 40 45 Gln Arg Gln Lys Ala Met Asp Ala Phe Phe Glu Ala Phe Gly Ile Asp 50 55 60 Gly Met Glu Pro Gly Asp Pro Ala Arg Ala Ile Ser Arg Gly Gly Val 65 70 75 80 Val Ile Leu Val Tyr Arg Ser Glu Glu Lys Asn Asp Asp His Lys Thr 85 90 95 Thr Cys Arg Arg Asn His Ile Pro His * 100 105 <210> 499 <211> 106 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7712..8029) <400> 499 Met Thr Ile Thr Lys Gln Arg Val Glu Glu Ile Ile Ser Arg Ile Glu 1 5 10 15 Met Tyr Gly His Gly Ala Gly Tyr Ile Ala Asp Glu Val Asn Asp Leu 20 25 30 Ala Ile Leu Ala Leu Asn Leu Ser Asn Ile Ala Asn Leu Lys Arg Tyr 35 40 45 Glu Leu Asp Met Gly Gly Cys Asp Ser Cys Gly Gln Asp Cys Gly Ala 50 55 60 Asp Met Thr Glu Asp Pro Asp Gly Asp Tyr Val Leu Phe Asp Asp Val 65 70 75 80 Val Lys Leu Phe Glu Phe Asp Thr Thr Thr Gln Lys Leu Glu Ile Pro 85 90 95 Ala Lys Glu Ala Ala Ser Gly Gln Asp * 100 105 <210> 500 <211> 146 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8016..8453) <400> 500 Val Gly Lys Ile Asp Tyr Gln Ala Leu Arg Glu Ala Ala Gln Asn Tyr 1 5 10 15 Gln Ser Thr Leu Ala Trp Tyr Gln Ala Thr Pro Asp Ser Pro Asn Ala 20 25 30 Glu Arg Asp Cys Asp Ala Ala Leu Ala Ala Phe Lys Arg His Ile Arg 35 40 45 His Arg Glu Ala Asp Ile Ile Ala Asp Leu Leu Asp Gly Leu Glu Glu 50 55 60 Ala Lys Ser Gln Leu Asn Glu Gln Arg Glu Tyr Tyr Glu Gly Val Ile 65 70 75 80 Ser Asp Gly Ser Lys Arg Ile Ala Glu Leu Glu Ala Arg Glu Val Gln 85 90 95 Leu Pro Thr Arg Tyr Asp Leu Arg Tyr Gly His Pro Ile Asn Ala Asp 100 105 110 Glu Arg His Val Met Ile Pro Lys Glu Asn Gly Ser Trp Leu Tyr Leu 115 120 125 Ile Asp Leu Glu His Ala Leu Arg Val Ala Gly Ile Arg Ile Lys Gly 130 135 140 Glu * 145 <210> 501 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8455..8646) <400> 501 Met Asn Gly Gln Ile Ser Ile Val Arg Pro Gly Ala Cys Asp Asp Arg 1 5 10 15 Glu Ile Arg Met Ile Ile Arg Leu Ala Met Gly Lys Thr Ile Thr Ala 20 25 30 Leu Ile Thr Pro Glu Asn Leu Ala Leu Ala Leu Thr Gly Lys Ser Asp 35 40 45 Met Pro Val Glu Leu Lys Leu Arg Asn Val Glu Ile Lys Val Lys * 50 55 60 <210> 502 <211> 196 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8649..9236) <400> 502 Met Thr Thr Ile Thr Lys Asp Arg Leu Leu Thr Ile Gln His Trp Arg 1 5 10 15 Glu Thr Tyr Gly Pro Gly Ser Asn Val Val Leu Pro Ala Glu Glu Ala 20 25 30 Glu Glu Leu Ala Arg Ile Ala Leu Ala Ser Leu Ala Ala Val Ser Asp 35 40 45 Glu Arg Ala Ala Tyr Glu Leu Phe Met Glu Lys Arg Phe Gly Glu Ser 50 55 60 Val Asp Arg Arg Arg Ala Lys Asn Gly Asp Arg Asp Tyr Met Val Trp 65 70 75 80 Asp Met Ala Leu Gly Trp Ile Ile Trp Cys His Arg Ala Ala Met Leu 85 90 95 Gln Ala Gly Asn Phe Arg Glu Asn Lys Gly Ser Ser Thr Asn Asn Phe 100 105 110 Arg Glu Ile Ser Glu Thr Ser Thr Asn Tyr Pro Val Thr Pro Asp Gly 115 120 125 Trp Ile Ser Cys Ser Glu Arg Met Pro Asp Asp Gly Gln His Val Ile 130 135 140 Ile Leu Cys Asp Gly Ala Phe Val Leu Tyr Ala Gln Tyr Arg Asp Gly 145 150 155 160 Glu Phe Phe Asp Val Val Arg Asn Gly Asp Glu Phe Phe Glu Thr Gln 165 170 175 Ser Arg Asn Val Thr Asp Trp Met Pro Leu Pro Glu Pro Pro Gln Glu 180 185 190 Val Arg Gln * 195 <210> 503 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9445..9600) <400> 503 Met Leu Thr Gly Ala Phe Leu Cys Leu Pro Tyr Gly Gly Met Pro Glu 1 5 10 15 Ala Asp Ser Leu Lys His Pro Gln Gln Phe Tyr Leu Thr Leu Ala Leu 20 25 30 Pro Gln Thr Val Phe Thr Arg Tyr Gly Asn Ser His Ile Val Met Asn 35 40 45 Ser Val Pro * 50 <210> 504 <211> 71 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9645..9857) <400> 504 Met Leu Asp Thr Cys Arg Leu Ala Ser Tyr Ala Pro Lys Gly Lys Glu 1 5 10 15 Lys Gln Ala Met Lys Gln Gln Lys Ala Met Leu Ile Ala Leu Ile Val 20 25 30 Ile Cys Ile Thr Val Ile Val Thr Ala Leu Val Thr Arg Lys Asp Leu 35 40 45 Cys Glu Val Arg Ile Arg Thr Gly Gln Thr Glu Val Ala Val Phe Thr 50 55 60 Ala Tyr Glu Pro Glu Glu * 65 70 <210> 505 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10025..10303) <400> 505 Met Ala His Asp Thr Lys Leu Tyr Asn Ser Asp Asp Ser Ala Val Phe 1 5 10 15 Ala Ser Arg Arg Gly Arg Cys Phe His Ala Phe Lys Ser Asp Trp Tyr 20 25 30 Gln His Pro Pro Cys Thr Glu Glu Gln Ala Glu Trp Leu Ile Gln Cys 35 40 45 Tyr Arg Arg Arg Gly Cys Glu Val Lys Lys Ala Leu Ser Leu Asp Tyr 50 55 60 Arg His Trp Ile Ile Ser Val Arg Leu Pro Tyr Ser Glu Arg Pro Pro 65 70 75 80 Arg Pro Ser Arg Thr Phe Gln Gln Arg Ile Trp Arg * 85 90 <210> 506 <211> 350 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10305..11354) <400> 506 Val Arg Val Leu Leu Arg Pro Val Leu Val Pro Glu Leu Gly Leu Val 1 5 10 15 Ile Val Lys Pro Gly Arg Glu Ser Met Ser Ala Phe His Asn Gly Arg 20 25 30 Ile Leu Val Glu Pro Glu Pro Lys Ser Met Arg Ala Leu Pro Ser Gly 35 40 45 Val Val Pro Ala Val His Gln Pro Leu Ala Glu Asp Lys Ser Leu Leu 50 55 60 Pro Phe Phe Ser Asp Glu Arg Val Ile Arg Ala Ala Gly Gly Ala Gly 65 70 75 80 Ala Leu Ser Asp Trp Leu Leu Arg His Val Lys Ser Cys Gln Trp Leu 85 90 95 His Gly Asp Tyr His His Ser Glu Thr Val Ile His Arg Tyr Gly Thr 100 105 110 Gly Ala Met Val Leu Cys Trp His Cys Asp Asn Gln Leu Arg Glu Gln 115 120 125 Thr Ser Asp Ser Leu Asp Gln Leu Ala Gln Gln Asn Leu Ala Ala Trp 130 135 140 Met Ile Asp Ile Ile Arg His Ala Met Asn Gly Ala Gln Glu Arg Glu 145 150 155 160 Leu Ser Leu Ala Glu Leu Ser Trp Trp Ala Val Arg Asn Gln Val Ala 165 170 175 Asp Ala Leu Pro Glu Ala Val Leu Arg Arg Ser Leu Gly Leu Arg Ala 180 185 190 Glu Lys Ile Arg Ser Val Tyr Arg Glu Ser Asp Ile Ile Pro Gly Glu 195 200 205 Gln Thr Ala Thr Ser Ile Leu Lys Gln Arg Thr Lys Asn Ile Ala Leu 210 215 220 Pro Ser His Thr His Gln Gln Gln Asn Pro Pro Gln Glu Lys Thr Val 225 230 235 240 Val Ser Ile Ala Val Asp Pro Glu Ser Pro Glu Ser Phe Arg Lys Arg 245 250 255 Pro Lys Arg Arg Arg Trp Val Asn Glu Lys Tyr Thr Arg Trp Val Lys 260 265 270 Thr Gln Pro Cys Ala Cys Cys Gly Lys Pro Ala Asp Asp Pro His His 275 280 285 Leu Ile Gly His Gly Gln Gly Gly Met Gly Thr Lys Ser His Asp Ile 290 295 300 Phe Thr Leu Pro Leu Cys Arg Glu His His Asn Glu Leu His Ala Asp 305 310 315 320 Pro Leu Ala Phe Glu Glu Lys His Gly Ser Gln Val Asp Leu Ile Phe 325 330 335 Arg Phe Leu Asp His Ala Phe Ala Thr Gly Val Leu Gly * 340 345 <210> 507 <211> 125 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11367..11741) <400> 507 Met Arg Ile Glu Phe Val Leu Leu Tyr Pro Pro Thr Val Asn Thr Tyr 1 5 10 15 Trp Arg Arg Arg Gly Ser Thr Tyr Phe Val Ser Lys Ala Gly Glu Arg 20 25 30 Tyr Arg Arg Ala Val Ala Leu Ile Val Arg Gln Gln Arg Leu Lys Leu 35 40 45 Ser Leu Ser Gly Arg Leu Ala Ile Lys Ile Ile Ala Glu Pro Pro Asp 50 55 60 Lys Arg Arg Arg Asp Leu Asp Asn Ile Leu Lys Ala Pro Leu Asp Ala 65 70 75 80 Leu Thr His Ala Gly Leu Leu Met Asp Asp Glu Gln Phe Asp Glu Ile 85 90 95 Asn Ile Val Arg Ala Gln Pro Val Ser Gly Gly Arg Leu Gly Val Lys 100 105 110 Ile Tyr Pro Ile Met Leu Glu Gly Gln Val Lys Lys * 115 120 <210> 508 <211> 274 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11738..12559) <400> 508 Met Lys Leu Glu Asp Leu Pro Lys Tyr Tyr Ser Pro Lys Ser Pro Gly 1 5 10 15 Leu Thr Asp Ala Ser Ala Ser Thr Ser Lys Asp Thr Leu Ser Ile Thr 20 25 30 Asp Val Met Ala Ala Gln Gly Met Thr Gln Asn Trp Ala Glu Met Gly 35 40 45 Phe Ser Ala Phe Leu Gly Lys Met Gly Ile Ser Met Asn Asp Arg Glu 50 55 60 Arg Ala Thr Glu Leu Leu Thr Glu Tyr Ala Leu Ser Arg Cys Asp Arg 65 70 75 80 Val Ala Ala Leu Arg Lys Leu Pro Ala Glu Ile Lys Pro Ala Val Met 85 90 95 Arg Ile Met Ala Ser Tyr Ala Phe Glu Asp Tyr Ala Arg Ser Ala Ala 100 105 110 Ser Lys Lys Gln Cys Pro Cys Cys His Gly Lys Lys Phe Ile Glu Ser 115 120 125 Glu Val Phe Thr Asn Lys Ile Gln Tyr Pro Asp Gly Lys Pro Pro Val 130 135 140 Trp Ala Lys Cys Thr Lys Gly Val Tyr Pro Ser Tyr Trp Glu Glu Trp 145 150 155 160 Lys Lys Val Arg Glu Val Val Lys Val Ala Cys Pro Glu Cys Gly Gly 165 170 175 Lys Gly Glu Val Ser Thr Ala Cys Lys Asp Phe Arg Gly Arg Gly Val 180 185 190 Ala Ile His Arg Glu Glu Ser Val Lys Arg Gly Met Pro Val Ile Arg 195 200 205 Asp Cys Gln Arg Cys Gly Gly Arg Gly Tyr Glu Arg Leu Pro Ser Thr 210 215 220 Glu Ala Phe Asn Ala Ile Cys Asn Val Thr Asp Ala Ile Ser Leu Asp 225 230 235 240 Thr Trp Lys Lys Thr Val Lys Arg Phe Tyr Asp Thr Leu Val Val Gln 245 250 255 Phe Asp Ile Glu Glu Ala Trp Ala Glu Gln Gln Leu Lys Lys Val Thr 260 265 270 Arg * <210> 509 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13424..13609) <400> 509 Val Leu Val Leu Asn Ser Pro Gly Gly Thr Arg His His Ala Leu Pro 1 5 10 15 Gln Lys Cys Tyr Phe Cys Phe Ser Gln Thr Ile Ile Val Ile Pro Leu 20 25 30 Phe Pro Ala Ala His Gly Ala Ala Phe Phe Leu Arg Pro Ala Thr Gly 35 40 45 Arg Trp Ser Ser Cys Asp Leu Ile Pro Val Pro Ala Phe * 50 55 60 <210> 510 <211> 167 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12972..13472) <400> 510 Val Ala Lys His Gly Ala Gly Cys Leu Pro Val Asn Ser Val Pro Ala 1 5 10 15 Pro Glu Ser Ala Ile Ile Pro Tyr Thr Trp Leu Leu Ile Ala Pro Pro 20 25 30 His Arg Gly Ile Arg His Ala Val Val Phe Leu Ile Asn Ser Lys Gln 35 40 45 Lys Asn Gln Ala Leu Cys Arg Leu Phe Leu Phe Ile Thr Gly His Ser 50 55 60 Asn Thr Thr Met Pro Gln Thr Ser Pro Pro Ser Ala Ser Thr Asp Met 65 70 75 80 Ile Leu Leu Val Lys Ser Thr Ile Thr Thr Arg Asn Ser Arg Ser Ala 85 90 95 Ala Thr Ala Arg Arg Ser Phe Thr Val Thr Gly Asn Ser Pro Asp Glu 100 105 110 Asp Pro Glu His Arg Gln Ser Leu Pro Ala Pro Cys Ala Leu Pro Ala 115 120 125 Gln Phe Arg Arg Leu Pro Pro Gln Trp Pro Pro Pro His Pro Ala His 130 135 140 Leu Pro Leu His Ala Tyr Arg Val Ser His Pro Arg Ser His Val Thr 145 150 155 160 Pro His Asp Asp Gln Phe * 165 <210> 511 <211> 646 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13638..15575) <400> 511 Met Ser Ile Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Glu Lys Leu Thr His Lys Leu Lys Glu Gly Trp Gln Pro Phe 20 25 30 Gly Ser Pro Val Ala Ile Thr Pro Tyr Thr Leu Met Gln Ala Ile Ala 35 40 45 Ala Glu Gly Asp Val Thr Thr Pro Val Val Val Pro Gly Thr Gly Asp 50 55 60 Gly Gly Tyr Pro Gly Val Val Thr Thr Glu Pro Asp Tyr Tyr Tyr Val 65 70 75 80 Ile Pro Leu Ala Gly Gln Ser Asn Gly Met Ala Tyr Gly Glu Gly Leu 85 90 95 Pro Leu Pro Gln Thr Tyr Asp Arg Pro Asp Pro Arg Ile Lys Gln Leu 100 105 110 Ala Arg Arg Ser Thr Val Thr Pro Asp Gly Ala Pro Cys Lys Tyr Asn 115 120 125 Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln Asp Met Ser 130 135 140 Arg Leu Asn His Pro Lys Ala Asp Leu Ser Lys Gly Gln Tyr Gly Thr 145 150 155 160 Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro Phe Ile Pro 165 170 175 Ala Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly Gly Ser Ala 180 185 190 Phe Thr Thr Gly Ala Asp Gly Thr Tyr Ser Asp Val Thr Gly Ala Ser 195 200 205 Glu Ser Ser Thr Arg Trp Gly Val Gly Arg Pro Leu Tyr Lys Asp Leu 210 215 220 Ile Gly Arg Thr Lys Ala Ala Leu Ala Lys Asn Pro Lys Asn Val Leu 225 230 235 240 Leu Ala Val Val Trp Met Gln Gly Glu Phe Asp Phe Asp Gly Thr Pro 245 250 255 Ala Asn His Thr Ala Arg Phe Thr Glu Val Val Glu Gln Tyr Arg Thr 260 265 270 Asp Leu Ala Asp Met Val Gly Gln Cys Ala Gly Gly Ser Ala Asp Gly 275 280 285 Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Phe Trp Lys Gln Lys Ser 290 295 300 Glu Ser Thr Tyr Gln Thr Val Tyr Gly Ser Tyr Lys Asn Lys Thr Glu 305 310 315 320 Lys Asn Ile His Phe Val Pro Phe Met Thr Asp Glu Asn Gly Ala Asn 325 330 335 Val Pro Thr Asn Lys Pro Glu Glu Asp Pro Asp Ile Pro Ala Ser Gly 340 345 350 Tyr Tyr Gly Ala Ala Ser Arg Thr Ser Ala Asn Trp Thr Ser Ala Asp 355 360 365 Arg Ala Ser His Phe Ser Ser Trp Ala Arg Arg Gly Ile Ile Ser Asp 370 375 380 Arg Leu Ala Ser Ala Ile Leu Leu His Ala Gly Arg Thr Ala Glu Leu 385 390 395 400 Val Gly Gly Glu Gln Val Val Met Pro Pro Asp Glu Lys Pro Ser Pro 405 410 415 Asp Thr Pro Ser Thr Pro Ser Thr Asp Gly Lys Ser Val Thr Thr Leu 420 425 430 Leu Tyr Tyr Arg Ala Thr Glu Ser Gly Gly Leu Leu Asn Pro Gln Gly 435 440 445 Trp Gly Ala Glu Gly Gly Arg Ala Leu Val Val Asp Asp Ala Gly Ala 450 455 460 Ala Gly Gly Lys Ala Leu Arg Trp Thr Lys Gln Thr Gly Ser Ser Ser 465 470 475 480 Trp Phe Met Gln His Asp Ala Gly Asn Gly Ala Asp Leu Leu Glu Lys 485 490 495 Gly Gly Leu Ile Ser Cys Arg Phe Lys Val Asp Gly Thr Leu Thr Ala 500 505 510 Asn Gln Tyr Ala Leu Ala Leu Tyr Trp Pro Val Ser Ser Leu Pro Gln 515 520 525 Gly Val Thr Leu Glu Gly Asn Ala Gly His Asn Leu Leu Ala Ser Phe 530 535 540 Tyr Val Gln Ser Asp Ala Thr Asp Leu Asn Val Met Tyr His Lys Gly 545 550 555 560 Asn Ala Gly Gln Asn Thr Lys Leu Gly Ser Phe Gly Ala Phe Asp Asn 565 570 575 Glu Trp His Thr Leu Gly Phe Arg Phe Ala Gly Asn Asn Ser Ile Glu 580 585 590 Val Thr Pro Val Ile Asp Gly Lys Asp Gly Thr Pro Phe Met Leu Ser 595 600 605 Gln Ser Pro Val Gly Thr Phe Thr Ala Asp Lys Leu Arg Val Thr Asp 610 615 620 Ile Thr Ser Gly Ala Thr Tyr Pro Val Leu Ile Glu Ser Ile Thr Val 625 630 635 640 Glu Val Asn Asn Pro * 645 <210> 512 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15723..15905) <400> 512 Met Arg Phe Val Gln Leu Ile Leu Leu Tyr Phe Cys Thr Val Val Cys 1 5 10 15 Thr Leu Tyr Leu Val Ser Gly Gly Tyr Lys Val Ile Arg Asn Tyr Ile 20 25 30 Arg Lys Lys Ile Asp Ala Ala Ala Ala Glu Lys Ile Ser Ala Ser Gln 35 40 45 Ser Ala Gly Thr Lys Pro Glu Glu Pro Leu Ile Ser * 50 55 60 <210> 513 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15943..16212) <400> 513 Met Ser Glu Ile Lys Ser Leu Val Thr Ala Glu Ala Val Lys Asp Val 1 5 10 15 Leu Arg Ser Glu Glu Val Arg Ser Ala Leu Lys Gln Gln Leu Arg Gln 20 25 30 Asn Leu Glu Ala Arg Leu Asp Ala Glu Val Asp Ala Ile Leu Asp Glu 35 40 45 Leu Leu Gly Gly Pro Ala Ala Pro Glu Pro Glu Asp Gly Ala Gly Asp 50 55 60 Ser Ala Val Ser Asp Gly Val Val Ser Gln Pro Asp Gly Ser Ser Glu 65 70 75 80 Pro Gln Pro Gly Gly Glu Met Met Met * 85 <210> 514 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16288..16503) <400> 514 Met Tyr Gln Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser 1 5 10 15 Ala Val Gly Thr Gly Tyr Trp Leu Leu Gln Leu Leu Asp Lys Val Ser 20 25 30 Pro Ser Gln Trp Val Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly 35 40 45 Leu Leu Thr Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Arg Glu Asp Arg 50 55 60 Arg Lys Ala Ala Arg Gly Glu * 65 70 <210> 515 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16508..16852) <400> 515 Met Lys Lys Lys Tyr Glu Leu Val Val Lys Gly Ile Asn Asn Tyr Pro 1 5 10 15 Asp Lys Ile Thr Val Thr Val Ala Leu Glu Ile Gly Gly Tyr Pro Ser 20 25 30 Leu Leu Leu Pro Asp Val Ala Ile Ser Leu Asp Arg Thr Glu Gly Ala 35 40 45 Thr Leu Glu Phe Tyr Glu Ala Glu Ala Lys Lys Gln Ala Lys Gln Phe 50 55 60 Phe Met Asp Val Ala Ala Gly Leu Cys Glu Gly Asp Gly Pro Leu Pro 65 70 75 80 Glu Lys Arg Pro Val Ile Leu Glu Ala Gln Asp Val Leu Ile Thr Tyr 85 90 95 Arg Gly Lys Leu Pro Gly Ile Ile Thr Gly Ser Leu Lys Thr Pro Pro 100 105 110 Leu Ala * <210> 516 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16903..17436) <400> 516 Met Asn Ala Lys Ile Arg Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Gly Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Thr Arg Val Asp Gly Lys Pro Val Ile 50 55 60 Pro Gly Met Lys Leu Ser Lys Glu Lys Cys Asp Arg Val Asn Ala Ile 65 70 75 80 Glu Arg Asp Lys Ala Leu Ala Trp Val Glu Lys Asn Ile Arg Val Pro 85 90 95 Leu Thr Glu Pro Gln Lys Ala Gly Ile Ala Ser Phe Cys Pro Tyr Asn 100 105 110 Ile Gly Pro Gly Lys Cys Phe Pro Ser Thr Phe Tyr Arg Arg Ile Asn 115 120 125 Ala Gly Asp Arg Lys Gly Ala Cys Glu Ala Ile Arg Trp Trp Ile Lys 130 135 140 Asp Gly Gly Arg Asp Cys Arg Ile Arg Ser Asn Asn Cys Tyr Gly Gln 145 150 155 160 Val Ser Arg Arg Asp Gln Glu Ser Ala Leu Ala Cys Trp Gly Ile Asp 165 170 175 Arg * <210> 517 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17707..18276) <400> 517 Met Asn Met Met Ala Val Pro Phe His Gly Asn Ser Leu Tyr Val Val 1 5 10 15 Asn His Asn Gly Glu Pro Tyr Val Pro Met Lys Pro Val Val Ala Gly 20 25 30 Met Gly Leu Ala Trp Gln Ser Gln Leu Ala Lys Leu Arg Gln Arg Phe 35 40 45 Ala Ser Thr Ile Thr Glu Ile Val Met Val Ala Glu Asp Gly Lys Gln 50 55 60 Arg Asn Met Val Ser Met Pro Leu Arg Lys Leu Ala Gly Trp Leu Gln 65 70 75 80 Thr Ile Asn Pro Asn Lys Val Lys Pro Glu Ile Arg Asp Lys Val Ile 85 90 95 Arg Tyr Gln Glu Glu Cys Asp Asp Val Leu Tyr Glu Tyr Trp Thr Lys 100 105 110 Gly Phe Val Val Asn Pro Arg Lys Met Ser Val Met Glu Glu Leu Asn 115 120 125 Gln Ala Cys Ala Asp Met Lys Arg Asp Lys Asn Ile Ala Ser Val Phe 130 135 140 Ala Thr Gly Leu Asn Glu Trp Lys Gln Val Lys Ala Ala His Val Ser 145 150 155 160 Lys Ile Arg Thr Leu Val Asn Glu Ala Asn Met Leu Ile Asp Phe Val 165 170 175 Leu Ala Asp Thr Gly Lys Gly Lys Ile Thr Lys Ala Asp * 180 185 <210> 518 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18430..18897) <400> 518 Met Asn Arg Val Leu Cys Val Val Ile Ile Val Met Ala Val Gly Cys 1 5 10 15 Gly Ala Leu Trp Leu Ala Thr Asn His Tyr Arg Asp Asn Ala Leu Thr 20 25 30 Tyr Lys Ala Gln Arg Asp Lys Lys Ala Arg Glu Leu Glu Gln Ala Asn 35 40 45 Ala Thr Ile Thr Asp Met Gln Val Arg Gln Arg Asp Val Ala Ala Leu 50 55 60 Asp Ala Lys Tyr Ser Arg Glu Leu Ala Asp Ala Arg Ala Glu Asn Glu 65 70 75 80 Thr Leu Arg Ala Asp Val Ala Ala Gly Arg Lys Arg Leu Arg Ile Asn 85 90 95 Ala Thr Cys Pro Gly Thr Val Arg Glu Ala Thr Gly Thr Ser Gly Val 100 105 110 Gly Asn Asp Ala Ala Val Glu Leu Ser Pro Val Ala Gly Arg Asn Val 115 120 125 Leu Gly Ile Arg Asp Gly Ile Ile Ser Asp Gln Ala Ala Leu Arg Met 130 135 140 Leu Gln Glu Tyr Ile Arg Thr Gln Cys Ile Asn * 145 150 155 <210> 519 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18650..18856) <400> 519 Met Arg Glu Leu Lys Met Lys Leu Cys Val Leu Met Leu Pro Leu Val 1 5 10 15 Val Ser Ala Cys Gly Ser Thr Pro Pro Ala Pro Val Pro Cys Val Lys 20 25 30 Pro Pro Ala Pro Pro Ala Trp Ala Met Met Pro Pro Ser Asn Ser Leu 35 40 45 Arg Leu Leu Asp Glu Thr Phe Ser Val Ser Glu Thr Glu Ser Ser Ala 50 55 60 Thr Arg Gln His * 65 <210> 520 <211> 75 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18921..19145) <400> 520 Met Lys Lys Leu Leu Val Thr Val Lys Pro Phe Gln Gly Thr Ile Pro 1 5 10 15 Phe Arg Ile Leu Gln Arg Gly Arg Val Leu Val Glu Gly Ser Phe Ser 20 25 30 Gly Lys Cys Thr Gln Leu His Ser Arg Thr Phe Gln Val Asn Ala Thr 35 40 45 Asn Glu Glu Leu Thr Val Glu Cys Thr Met Asn Ala Ala Lys Cys Arg 50 55 60 Met Val Ser Ala Ala Leu Gln Pro Val Cys * 65 70 <210> 521 <211> 73 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19142..19360) <400> 521 Leu Ser Asp Leu Ile Ile His Ala Arg Tyr Cys Arg Arg Ile Pro Ala 1 5 10 15 Leu Thr Glu Thr Ala Ala Arg Pro Gly Glu Ser Ser Ala Arg Val Cys 20 25 30 Gly Asp Asn Gln Lys Arg Tyr Thr Pro Gly Phe Thr Ala Leu Thr Glu 35 40 45 Arg Gly Val Val Pro Ser Trp Ser Leu Val Arg Cys Asp Gly Gly Arg 50 55 60 Ser Arg Met Phe Ile Thr Ile Asn * 65 70 <210> 522 <211> 47 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19502..19642) <400> 522 Met Asp Phe Met Leu Thr Val Ser Gly Val Val Ile Leu Ser Ile Ala 1 5 10 15 Tyr Thr Ala Asp Lys Tyr Gly Cys His Leu Leu Ser Arg Ile Gly Ala 20 25 30 Tyr Cys Ser Leu Met Leu Ile Phe Ser Ser Leu Phe Phe Glu * 35 40 45 <210> 523 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19772..19957) <400> 523 Met Ser Ser Lys Asn Arg Pro Arg Arg Thr Thr Ile Arg Asn Ile Arg 1 5 10 15 Phe Pro Asn His Met Ile Glu Gln Ile Asn Ile Ala Leu Glu His Lys 20 25 30 Gly Ser Gly Asn Phe Ser Ala Trp Val Ile Glu Ala Cys Arg Arg Arg 35 40 45 Leu Ser Thr Glu Arg Ser Gly Met Asn Tyr Ile Ile Lys * 50 55 60 <210> 524 <211> 122 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19999..20364) <400> 524 Met Ala Val Leu Arg Thr Leu Pro Gly Arg Ile Lys Thr Leu Asn Thr 1 5 10 15 Arg Arg Ile Asn Val Leu Arg Gly Glu Gln Arg Arg Val Ser Gly Ser 20 25 30 Ala Arg Val Ser Leu Lys Arg Arg Ile Trp Arg Arg Asp Ala Gly His 35 40 45 Cys Cys Leu Cys Arg Arg Val Val Asp Leu Cys Asp Ser Glu Leu Asp 50 55 60 His Arg Ile Ala Leu Gln Phe Gly Gly Gly Asn Glu Glu Thr Asn Leu 65 70 75 80 Trp Thr Leu Cys Thr Glu Cys His Arg Gln Lys Ser Ala Ser Glu Ala 85 90 95 Ala Ser Gly Met Pro Asp Pro Thr Leu Pro Glu Leu Pro Asp Gly Thr 100 105 110 Leu Arg Ala Asp Gly Ile Thr Gly Leu * 115 120 <210> 525 <211> 188 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20654..21217) <400> 525 Val Leu Thr Thr Gln Lys Arg Lys Phe Ala Leu Ala Leu Met Ser Gly 1 5 10 15 Lys Asn Lys Thr Ala Ser Ala Leu Ala Ala Gly Tyr Ser Ala Lys Thr 20 25 30 Ala Arg Val Lys Gly Ser Gln Leu Ala Lys Asp Pro Glu Val Leu Ala 35 40 45 Phe Ile Ala Arg Lys Gln Cys Glu Thr Val Glu Val Asp Glu Val Pro 50 55 60 Val Tyr Arg Gln Lys Lys Ser Glu Pro Glu Asp Lys Pro Arg Arg Arg 65 70 75 80 Glu Ala Ala Ala Ile Pro Gln Pro Asp Glu Thr Asn Pro Glu Met Pro 85 90 95 Pro Pro Val Val Ile Ser Pro Gly Ile Glu Tyr Met Glu Asp Gly Leu 100 105 110 Pro Asp Pro Val Lys Ala Met Gly Arg Leu Leu Val Glu Asn Ile Asn 115 120 125 Thr Asp Pro Arg Leu Ala Leu Asp Ala Ala Tyr Lys Leu Ala Gln Phe 130 135 140 Thr His His Lys Lys Gly Asp Ala Gly Lys Lys Ser Ala Lys Gly Asp 145 150 155 160 Ala Ala Lys Lys Ala Ala Asn Arg Phe Ala Val Pro Pro Pro Pro Arg 165 170 175 Leu Val Val Asn Asn Asp Asn Glu Gly Asn Gly * 180 185 <210> 526 <211> 554 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21214..22875) <400> 526 Met Ile Pro Val Trp Ser Thr Ala Cys Pro Asp Trp Ala Glu Arg Leu 1 5 10 15 Lys Lys Gly Leu Ser Ile Ile Pro Ala Pro Ile Tyr Pro Glu Gln Ala 20 25 30 Ala His Ala Leu Ala Ile Phe Lys Gln Leu Arg Ile Val Asp Ala Pro 35 40 45 Gly Ser Pro Thr Phe Gly Glu Ser Cys Ala Gln Trp Val Phe Asp Leu 50 55 60 Val Ala Ala Leu Phe Gly Ser Tyr Asp Ala Gln Thr Gly Val Arg His 65 70 75 80 Ile Lys Glu Val Phe Ile Leu Ile Pro Lys Lys Asn Ser Lys Ser Thr 85 90 95 Leu Ala Ala Gly Ile Met Met Thr Ala Leu Leu Leu Asn Trp Arg Gln 100 105 110 Ala Ala Gly Tyr Thr Ile Leu Ala Pro Thr Val Glu Val Ala Ala Asn 115 120 125 Ala Phe Asn Pro Ala Arg Asp Met Val Arg Arg Asp Asp Asp Leu Asp 130 135 140 Asp Leu Cys Gln Val Gln Thr His Ile Arg Thr Ile Thr His Arg Val 145 150 155 160 Thr Asp Thr Thr Leu Lys Val Val Ala Ala Asp Pro Asn Thr Val Ser 165 170 175 Gly Ile Lys Ser Val Gly Thr Leu Ile Asp Glu Leu Trp Leu Phe Gly 180 185 190 Lys Gln Tyr Lys Ala Glu Asp Met Leu Arg Glu Ala Ile Gly Gly Leu 195 200 205 Ala Ser Arg Pro Glu Gly Phe Val Val Tyr Thr Thr Thr Gln Ser Asn 210 215 220 Glu Pro Pro Ala Gly Val Phe Arg Gln Lys Leu Gln Tyr Ala Arg Asp 225 230 235 240 Val Arg Asp Gly Lys Ile His Asp Pro His Phe Leu Pro Val Ile Phe 245 250 255 Glu His Pro Pro Glu Met Val Glu Ser Gly Ala His Leu Leu Met Glu 260 265 270 Asn Leu Ala Met Val Asn Pro Asn Leu Gly Tyr Ser Val Asp Glu Ala 275 280 285 Phe Leu Tyr Arg Glu Tyr Arg Lys Ala Arg Glu Ala Gly Glu Glu Ala 290 295 300 Phe Arg Gly Phe Met Ser Lys His Ala Asn Val Glu Ile Gly Leu Ala 305 310 315 320 Leu Arg Ser Asp Arg Trp Ala Gly Ala Asp Phe Trp Glu Gln Gln Gly 325 330 335 Arg Arg Val Ser Leu Asp Asp Ile Leu Gln Arg Ala Asp Val Val Thr 340 345 350 Val Gly Ile Asp Gly Gly Gly Leu Asp Asp Leu Leu Gly Met Tyr Val 355 360 365 Ile Gly Arg Asp Arg Glu Thr Arg Glu Trp Leu Gly Trp Gly His Ala 370 375 380 Trp Ala His Glu Thr Ala Val Val Arg Arg Lys Ser Glu Ala Ser Arg 385 390 395 400 Phe Gln Asp Leu Val Ala Cys Gly Asp Met Thr Ile Val Arg Arg Val 405 410 415 Gly Asp Asp Thr Ala Glu Val Ala Glu Tyr Val Arg Arg Ile His Glu 420 425 430 Ala Glu Leu Leu Asp His Ile Gly Ile Asp Pro Ser Gly Val Gly Gln 435 440 445 Ile Leu Asp Ser Leu Ala Glu Ala Gly Ile Pro Asp Gly Ile Val Val 450 455 460 Gly Ile Ser Gln Gly Trp Lys Leu Gly Gly Ala Ile Lys Thr Thr Glu 465 470 475 480 Arg Lys Leu Ala Glu Gly Val Leu Val His Gly Asp Gln Pro Leu Met 485 490 495 Ala Trp Cys Val Gly Asn Ala Arg Val Glu Pro Lys Gly Asn Ala Ile 500 505 510 Leu Ile Thr Lys Gln Ala Ser Gly Arg Gly Lys Ile Asp Pro Leu Met 515 520 525 Ala Leu Phe Asn Ala Val Ser Leu Met Ser Leu Asn Pro Glu Pro Lys 530 535 540 Lys Lys Glu Tyr Ala Val Phe Phe Ile * 545 550 <210> 527 <211> 646 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22939..24876) <400> 527 Val Thr Leu Lys Arg Ala Cys Ser Leu Leu Thr Val Lys Ser Phe Ser 1 5 10 15 Glu Asp Glu Arg Val Ile Thr Gly Ile Ala Ser Thr Pro Ser Pro Asp 20 25 30 Arg Asp Gly Asp Ile Leu Glu Pro Glu Gly Ala Glu Phe Gly Ser Ala 35 40 45 Ile Pro Phe Leu Trp Gln His Asp His Ser Arg Pro Val Gly Gln Cys 50 55 60 Thr Val Arg Arg Val Ser Glu Gly Leu Glu Ile Thr Ala Thr Leu Val 65 70 75 80 Lys Pro Val Pro Asp Met Pro Ser Gln Leu Ala Ala Arg Leu Asp Glu 85 90 95 Val Trp Ala Ala Ile Lys Thr Gly Leu Val Arg Gly Leu Ser Val Gly 100 105 110 Phe Arg Pro His Glu Tyr Thr Phe Leu Asp Gly Gly Gly Leu His Phe 115 120 125 Leu Arg Trp Glu Leu Met Glu Val Ser Ala Val Thr Val Pro Ala Asn 130 135 140 Ala Glu Cys Thr Ile Arg Thr Ile Lys Ser Tyr Asp Arg Pro Phe Ser 145 150 155 160 Ala Ala Ser Gly Asn Arg Lys Pro Val Val Lys Ile Ala Ser Ser Ala 165 170 175 Gly Ala Ala Ala Gln Ser Thr Thr Val Phe His Lys Glu Lys Thr Ile 180 185 190 Met Asn Ile Gly Glu Gln Ile Lys Ser Phe Glu Asn Lys Arg Ala Ala 195 200 205 Leu Ala Ala Ser Leu Glu Glu Val Met Thr Lys Ala Ala Glu Glu Gly 210 215 220 Arg Thr Leu Asp Val Glu Glu Glu Glu His Tyr Asp Asn Thr Ala Ala 225 230 235 240 Glu Ile Arg Gln Val Asp Ala His Leu Lys Arg Leu Arg Glu Leu Glu 245 250 255 Ala Gly Lys Ala Ala Thr Ala Gln Pro Val Lys Gln Ala Gly Asn Gly 260 265 270 Asn Val Ala Ala Val Ala Ser Ala Pro Val Ile Arg Val Glu Gln Lys 275 280 285 Leu Asp Lys Gly Ile Gly Phe Ala Arg Phe Ala Lys Ser Leu Ala Ala 290 295 300 Ala Lys Gly Val Arg Ser Glu Ala Leu Glu Val Ala Arg Arg Gln Tyr 305 310 315 320 Pro Asp Asp Ser Arg Leu His His Val Leu Lys Ser Ala Val Gly Ala 325 330 335 Gly Thr Thr Thr Asp Pro Gln Trp Ala Gly Ser Leu Ser Glu Tyr Gln 340 345 350 Glu Tyr Ala Gln Asp Phe Ile Asp Tyr Leu Arg Pro Gln Thr Ile Ile 355 360 365 Gly Arg Phe Gly Gln Gly Gly Ile Pro Ala Leu Arg Gln Val Pro Phe 370 375 380 Asn Ile Arg Val His Ala Gln Val Ser Gly Gly Ala Ala Gly Trp Val 385 390 395 400 Gly Glu Gly Lys Ala Lys Pro Leu Thr Lys Phe Asp Phe Glu Ser Ile 405 410 415 Thr Phe Ser His Ala Lys Val Ser Ala Ile Ala Val Leu Thr Glu Glu 420 425 430 Leu Ile Arg Phe Ser Ser Pro Ala Ala Asp Ala Leu Val Arg Asn Ala 435 440 445 Leu Ala Glu Ala Val Val Ala Arg Leu Asp Thr Asp Phe Val Asp Pro 450 455 460 Lys Lys Ala Ala Val Ala Asp Val Ser Pro Ala Ser Ile Thr His Asp 465 470 475 480 Val Lys Gly Thr Ala Ser Thr Gly Asn Pro Asp Ala Asp Ala Glu Ala 485 490 495 Ala Phe Gly Gln Phe Val Ala Ala Asn Leu Gln Pro Thr Gly Ala Val 500 505 510 Trp Leu Met Ser Ser Thr Asn Ala Leu Ala Leu Ser Met Arg Lys Asn 515 520 525 Ala Leu Gly Gln Lys Glu Tyr Pro Asp Met Thr Leu Leu Gly Gly Ser 530 535 540 Phe Gln Gly Leu Pro Val Ile Val Ser Gln Tyr Val Gly Asp Gln Leu 545 550 555 560 Val Leu Val Asn Ala Pro Asp Ile Tyr Leu Ala Asp Asp Gly Gly Val 565 570 575 Ala Val Asp Met Ser Arg Glu Ala Ser Leu Glu Met Gln Ser Glu Pro 580 585 590 Gly Gly Asp Ser Thr Thr Pro Ser Pro Val Glu Leu Val Ser Met Phe 595 600 605 Gln Thr Gly Ser Val Ala Ile Arg Ala Glu Arg Trp Ile Asn Trp Arg 610 615 620 Arg Arg Arg Thr Ala Ala Val Ala Val Ile Thr Gly Val Asn Tyr Gly 625 630 635 640 Ser Ala Ser Gly Gly * 645 <210> 528 <211> 834 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25088..27589) <400> 528 Met Trp Asn Leu Leu Arg Arg Thr Arg Lys Asn Gln Lys Ser Gly Arg 1 5 10 15 Asp Val Arg Glu Ala Gly Trp Thr Ser Leu Phe Gln Ala Val Ala Glu 20 25 30 Pro Phe Ser Gly Ala Trp Gln Gln Gly Val Lys Ala Asp Pro Glu Ala 35 40 45 Val Leu Ser Phe His Ala Val Phe Ala Cys Ile Ser Leu Ile Ser Gln 50 55 60 Asp Ile Ala Lys Met Arg Leu Arg Leu Met Gln Thr Asp Ala His Gly 65 70 75 80 Ile Arg Arg Glu Thr Arg Arg Gly Asp Ile Ala Arg Leu Cys Arg Arg 85 90 95 Pro Asn Ala Gln Gln Asn Arg Ile Gln Phe Phe Glu Leu Trp Leu Asn 100 105 110 Ala Lys Leu Arg His Gly Asn Thr Val Val Leu Lys Ile Arg Asn Ala 115 120 125 Arg Gly Gln Ile Lys Glu Leu Arg Ile Leu Asp Trp Ser Arg Val Glu 130 135 140 Pro Leu Val Ala Asp Asp Gly Glu Val Phe Tyr Arg Ile Thr Pro Asp 145 150 155 160 Arg Asn Cys Gly Ile Thr Glu Ala Val Thr Val Pro Ala Arg Glu Val 165 170 175 Ile His Asp Arg Phe Asn Cys Phe Phe His Pro Leu Ile Gly Leu Pro 180 185 190 Pro Val Tyr Ala Ala Gly Leu Ala Ala Thr Gln Gly His His Ile Gln 195 200 205 Glu Asn Ser Thr Ser Phe Phe Arg Asn Gly Gly Arg Pro Ser Gly Val 210 215 220 Ile Glu Ile Pro Gly Ser Ile Thr Glu Glu Asn Ala Lys Lys Leu Lys 225 230 235 240 Ser Asn Trp Asp Ser Gly Tyr Thr Gly Glu Asn Ala Gly Lys Thr Ala 245 250 255 Ile Leu Ser Asn Gly Ala Lys Tyr Asn Pro Thr Thr Phe Ser Pro Val 260 265 270 Asp Ala Gln Thr Val Glu Gln Leu Lys Met Thr Ala Glu Ile Val Cys 275 280 285 Ser Val Phe Arg Val Pro Ala Tyr Lys Ile Gly Val Gly Gln Pro Pro 290 295 300 Ser Ser Asp Asn Val Glu Ala Leu Glu Gln Gln Tyr Tyr Ser Gln Cys 305 310 315 320 Leu Gln Thr Leu Ile Glu Ser Ile Glu Leu Leu Leu Asp Glu Ala Leu 325 330 335 Glu Thr Gly Glu Asn Glu Ser Thr Glu Phe Asp Val Thr Thr Leu Leu 340 345 350 Arg Met Asp Ser Glu Arg Arg Met Lys Thr Leu Gly Asp Ala Val Lys 355 360 365 Asn Thr Leu Leu Thr Pro Asn Glu Ala Arg Lys Arg Glu Asn Leu Pro 370 375 380 Pro Leu Ala Gly Gly Asp Ala Leu Tyr Leu Gln Gln Gln Asn Tyr Ser 385 390 395 400 Leu Glu Ala Leu Ser Arg Arg Asp Ala Arg Glu Asp Pro Phe Ala Ser 405 410 415 Ala Gly Lys Thr Val Ser Ser Gln Leu Pro Asp Gly Ala Ser Asp Gly 420 425 430 Asn Lys Ala Ile Ser Glu Thr Glu His Asp Ala Val Lys Ala Met Phe 435 440 445 Arg Gly Asp Thr Glu Lys Met Thr Glu Arg Glu Leu Ser Ile Ile Arg 450 455 460 Ala Leu Gly Glu Glu Phe Ser Thr Val Leu Ala Asp Leu Gln Arg Thr 465 470 475 480 Phe Glu Glu Lys Ile Ala Ala Gln Ala Gln Thr Phe Glu Glu Lys Leu 485 490 495 Ala Ser Gln Ser Val Val Leu Gln Lys Cys Val Thr Gly Asp Asp Val 500 505 510 Arg Pro Met Leu Glu Gln Met Val Lys Glu Ala Val Ser His Ile Pro 515 520 525 Val Pro Arg Asp Gly Arg Asp Tyr Asp Pro Asp Val Leu Gln Lys Ala 530 535 540 Val Asn Asp Ala Val Ala Asn Ile Pro Val Pro Ala Asp Gly Lys Ser 545 550 555 560 Ile Thr Pro Asp Asp Val Arg Pro Met Leu Glu Gln Met Val Lys Glu 565 570 575 Ala Val Ser His Ile Pro Val Pro Arg Asp Gly Arg Asp Tyr Asp Pro 580 585 590 Asp Val Leu Gln Lys Ala Val Asn Asp Ala Val Ala Lys Ile Pro Val 595 600 605 Pro Ala Asp Gly Lys Ser Ile Thr Pro Asp Asp Val His Pro Met Leu 610 615 620 Glu Gln Met Val Lys Glu Ala Val Ser His Ile Pro Val Pro Arg Asp 625 630 635 640 Gly Arg Asp Tyr Asp Pro Asp Val Leu Gln Lys Ala Val Asn Asp Ala 645 650 655 Val Ala Lys Ile Pro Val Pro Ala Asp Gly Lys Ser Ile Thr Pro Asp 660 665 670 Asp Val His Pro Met Leu Glu Gln Met Val Lys Glu Ala Val Ser His 675 680 685 Ile Pro Val Pro Arg Asp Gly Arg Asp Tyr Asp Pro Asp Val Leu Gln 690 695 700 Lys Ala Val Leu Glu Ala Val Ser Ala Leu Pro Ala Pro Gln Asp Gly 705 710 715 720 Arg Asp Ala Thr Ala Leu Glu Ile Leu Pro Ala Ile Asp Asp Gln Lys 725 730 735 Ser Phe Pro Arg Gly Ser Tyr Ala Thr His Gln Gly Gly Leu Trp Arg 740 745 750 Ala Tyr Glu Lys Thr Tyr Gly Met Arg Gly Trp Glu Cys Leu Val Asp 755 760 765 Gly Val Ala Asp Ile Asp Val Ser Met Thr Gly Glu Arg Ser Phe Ser 770 775 780 Val Val Val Arg Gln Ser Ser Gly Gln Arg Thr Glu Lys Thr Phe Ser 785 790 795 800 Leu Pro Val Met Leu Tyr Arg Gly Val Phe Arg Ile Gly Glu Thr Tyr 805 810 815 His Pro Gly Asp Thr Val Thr Trp Gly Ala Arg Cys Gly Thr Ala Thr 820 825 830 Val * <210> 529 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27669..27995) <400> 529 Val Thr Ala Leu Leu Thr Leu Glu Glu Ile Lys Ala His Leu Arg Val 1 5 10 15 Asp His Asp Ala Asp Asp Glu Met Leu Met Asp Lys Val Arg Gln Ala 20 25 30 Thr Ala Val Leu Leu Ala Tyr Ile Gln Gly Ser Arg Asp Lys Val Ile 35 40 45 Ser Glu Asp Gly Glu Leu Ile Pro Gly Glu Ala Leu Thr Arg Met Lys 50 55 60 Gly Ala Ala Met Arg Leu Thr Gly Met Leu Tyr Arg Asn Pro Asp Leu 65 70 75 80 Ala Glu Arg Glu Asp Leu Val Gln Gly Glu Leu Pro Phe Ser Val Ser 85 90 95 Val Leu Ile Tyr Asp Leu Arg Cys Pro Thr Val Leu * 100 105 <210> 530 <211> 117 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28005..28355) <400> 530 Met Ala Ile Ser Ala Gly Arg Leu Thr Gln Met Ile Ser Val Leu Asn 1 5 10 15 Pro Val Leu Thr Arg Asn Ala Ala Gly Glu Met Thr Glu Glu Trp Val 20 25 30 Ser Cys Gly Lys Ile His Ala Asp Ile Arg Gly Arg Ser Ser Arg Glu 35 40 45 Arg Met Gln Ser Gly Ala Glu Met Ala Gln Ala Glu Ile Arg Ile Trp 50 55 60 Val Arg Gly Gln Ser Gly Arg Glu Ile Thr Ala Ala Ser Arg Leu His 65 70 75 80 Val Leu Ser Gly Pro Trp Arg Asp His Val Leu Asn Val Val Gly Val 85 90 95 Pro Val Pro Asp Ala Thr Gly Gly Arg Leu Glu Ile Leu Cys Arg Leu 100 105 110 Gly Gly Glu Lys * 115 <210> 531 <211> 149 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28352..28798) <400> 531 Met Ile Glu Thr Leu Leu Asp Phe Ser Gly Leu Glu Asp Ile Ser Arg 1 5 10 15 Asp Leu Gln Leu Leu Ser Gly Ala Glu Asn Asn Arg Val Leu Arg Glu 20 25 30 Ala Thr Arg Ala Gly Ala Asn Val Leu Lys Glu Glu Val Val Ser Arg 35 40 45 Ala Pro Val Arg Arg Gly Lys Leu Arg Arg Asn Val Val Val Leu Ser 50 55 60 Arg Cys Ser Arg Asp Gly Gly Met Glu Ser Gly Val His Ile Arg Gly 65 70 75 80 Val Asn Pro Asp Thr Gly Asn Ser Asp Asn Thr Met Lys Ala Asp Asn 85 90 95 Pro Arg Asn Ala Phe Tyr Trp Arg Phe Val Glu Met Gly Thr Val Asn 100 105 110 Met Pro Pro His Pro Phe Val Arg Pro Ala Phe Asp Val Arg Ser Glu 115 120 125 Gln Ala Ala Gln Val Ala Ile Ala Arg Met Asn Arg Ala Ile Asp Glu 130 135 140 Val Leu Arg Arg * 145 <210> 532 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28795..29139) <400> 532 Met Thr Glu Ala Asp Leu Tyr Pro His Leu Ala His Leu Ala Gly Gly 1 5 10 15 Gln Val Tyr Pro Tyr Val Val Pro Leu Leu Asp Gly Arg Pro Ser Val 20 25 30 Ala Leu Pro Trp Val Val Phe Ser Leu Ile Ser Ser Val Ser Ala Asp 35 40 45 Val Met Gly Gly Gln Ala Glu Ser Ser Val Ser Val Gln Ile Asp Val 50 55 60 Tyr Ala Gly Thr Val Thr Gln Ala Arg Gln Ile Arg Gln Asp Ala Arg 65 70 75 80 Glu Ala Ile Met Leu Leu Ala Pro Gly Ser Val Ser Glu Met Gln Asp 85 90 95 Tyr Ile Pro Glu Asn Arg Cys Tyr Arg Ala Thr Leu Glu Phe Gln Val 100 105 110 Thr Val * <210> 533 <211> 239 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29198..29914) <400> 533 Met Ser Ala Leu Tyr Glu Arg Ser Gln Leu Thr Gln Val Met Ile Ser 1 5 10 15 Ser Ala Pro Ala Thr Ala Glu Thr Met Glu Lys Ala Glu Tyr Leu Arg 20 25 30 Leu Asp Cys Thr Ile Lys Glu Val Gln Phe Thr Ala Gly Gln Lys Gln 35 40 45 Asp Ile Asp Val Thr Thr Leu Cys Ser Thr Glu Gln Glu Asn Ile Asn 50 55 60 Gly Leu Gly Ala Ser Ser Glu Ile Ser Met Ser Gly Asn Phe Tyr Leu 65 70 75 80 Asn Gln Ala Gln Asn Ala Leu Arg Asp Ala Tyr Asp Asn Asp Thr Val 85 90 95 Tyr Ala Phe Lys Val Gln Phe Pro Ser Gly Lys Gly Phe Lys Phe Leu 100 105 110 Ala Glu Val Arg Gln His Thr Trp Ser Ser Gly Thr Asn Gly Val Val 115 120 125 Ala Ala Thr Phe Ser Leu Arg Leu Lys Gly Lys Pro Val Ser Tyr Val 130 135 140 Val Pro Leu Ala Phe Val Lys Asn Leu Asp Lys Thr Leu Thr Val Asn 145 150 155 160 Thr Gly Ala Leu Leu Thr Met Ser Val Ser Val Asn Gly Gly Thr Pro 165 170 175 Pro Tyr Lys His Ala Trp Lys Lys Asp Gly Gln Pro Val Glu Gly Gln 180 185 190 Thr Thr Asp Thr Phe Ser Lys Pro Gly Ala Gln Ser Gly Asp Lys Gly 195 200 205 Ala Tyr Thr Cys Glu Val Thr Asp Ser Ala Glu Gln Pro Gln Ser Ile 210 215 220 Thr Ser Asp Ala Cys Thr Val Thr Val Asn Gly Ala Gly Gly * 225 230 235 <210> 534 <211> 125 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29920..30294) <400> 534 Met Ala Lys Asp Leu Lys Thr Leu Ala Leu Ala Arg Leu Ser Gly Phe 1 5 10 15 Arg His Lys Thr Val Lys Val Pro Glu Trp Arg Asn Val Ser Val Val 20 25 30 Leu Arg Glu Pro Ser Ala Glu Ala Trp Tyr Leu Trp Gln Glu Val Leu 35 40 45 Asn Gly Asp Gly Glu Asp Asp Asp Thr Leu Ser Val Val Ala Lys Thr 50 55 60 Arg Arg Asn Leu Glu Ala Asp Val Thr Leu Phe Cys Asp Val Leu Cys 65 70 75 80 Asp Thr Asp Leu Gln Arg Val Phe Thr Pro Asp Asp Arg Glu Gln Val 85 90 95 Leu Ala Val Tyr Gly Pro Val His Ala Arg Leu Leu Arg Gln Ala Leu 100 105 110 Glu Leu Ile Ala Asp Ala Glu Ser Ala Arg Lys Lys * 115 120 <210> 535 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30318..30599) <400> 535 Met Arg Leu Ala Leu Arg Leu Gly Arg Thr Leu Ser Glu Leu Arg His 1 5 10 15 Ser Leu Ser Ala Ser Glu Ala Met Met Trp Met Glu Phe Asp Arg Val 20 25 30 Ser Pro Leu Gly Asp Glu Arg Gly Asp Ile Arg Asn Ala Gln Ile Val 35 40 45 Lys Ala Val Phe Gly Ala Gln Gly Met Asn Val Ala Leu Lys Asp Ala 50 55 60 Met Leu Cys Trp Gly Glu Asp Glu Asp Lys Pro Glu Val Asp Pro Phe 65 70 75 80 Ala Ala Leu Glu Asp Ala Leu Ser Leu Ala Ala Met Ser * 85 90 <210> 536 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30652..31077) <400> 536 Met Ala Thr Leu Arg Glu Leu Ile Ile Lys Ile Ser Ala Asn Ser Gln 1 5 10 15 Ser Phe Gln Ser Glu Ile Gln Arg Ala Ser Arg Met Gly Ser Glu Tyr 20 25 30 Tyr Arg Thr Leu Gln Asn Gly Gly Arg Gln Ala Ala Ala Ala Ala Arg 35 40 45 Glu Gln Arg Arg Ala Leu Ala Glu Leu Asn Ser Gln Leu Thr Glu Ile 50 55 60 Arg Gly Ser Ala Val Gly Met Ala Gly Ala Phe Ala Gly Ala Phe Ala 65 70 75 80 Ser Gly His Leu Ile Ser Leu Ala Asp Glu Trp Ser Ser Val Asn Ala 85 90 95 Arg Leu Lys Gln Ala Ser Gln Ser Ser Asp Glu Phe Ala Ser Ser Gln 100 105 110 Lys Val Leu Met Asp Ile Ser Gln Arg Thr Gly Thr Ala Phe Ser Asp 115 120 125 Asn Ala Ala Leu Phe Ala Arg Ser Ala Cys Leu Asp Ala * 130 135 140 <210> 537 <211> 953 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31037..33895) <400> 537 Met Arg Pro Cys Leu Pro Val Arg Pro Ala Ser Met Arg Glu Tyr Gly 1 5 10 15 Tyr Ser Ala Gly Asp Val Leu Lys Val Thr Glu Ala Ile Ser Thr Gly 20 25 30 Leu Lys Ile Ser Gly Ala Ser Thr Ala Glu Ala Gly Ser Val Ile Thr 35 40 45 Gln Phe Ser Gln Ala Leu Ala Gln Gly Val Leu Arg Gly Glu Glu Phe 50 55 60 Asn Ser Val Asn Glu Ser Gly Asp Arg Ile Val Arg Ala Leu Ala Ala 65 70 75 80 Gly Met Gly Val Ala Arg Lys Asp Leu Lys Ala Met Ala Asp Asp Gly 85 90 95 Lys Leu Thr Ala Asp Lys Val Val Pro Ala Leu Ile Ser Gln Leu Gly 100 105 110 Ile Leu Arg Asp Glu Tyr Ala Ala Met Pro Glu Thr Val Ser Ser Ser 115 120 125 Ile Thr Lys Val Glu Asn Ala Phe Met Ala Trp Val Gly Gly Ala Asn 130 135 140 Glu Ala Ser Gly Val Thr Lys Thr Leu Ser Gly Met Leu Asn Gly Val 145 150 155 160 Ala Gly Gln Ile Asp Asn Val Ala Thr Ala Val Gly Ala Leu Val Ala 165 170 175 Val Gly Val Ala Arg Tyr Phe Gly Asn Met Ala Ser Gly Ala Met Ser 180 185 190 Ala Thr Ala Gly Leu Val Thr Ala Ala Arg Asn Glu Val Ala Leu Ala 195 200 205 Glu Ala Gln Phe Arg Gly Thr Gln Ile Ala Thr Ala Arg Ala Arg Ala 210 215 220 Ala Val Tyr Arg Ala Gln Gln Ala Val Ala Ala Ala Arg Gly Thr Glu 225 230 235 240 Met Gln Ile Ala Ala Glu Ala Arg Leu Ala Ala Thr Gln Glu Arg Leu 245 250 255 Asn Arg Asn Ile Ala Ala Arg Thr Ala Ala Gln Asn Ala Leu Asn Ser 260 265 270 Thr Thr Ala Val Gly Ser Arg Leu Met Ser Gly Ala Leu Gly Leu Val 275 280 285 Gly Gly Val Pro Gly Leu Val Met Leu Gly Ala Ala Ala Trp Tyr Thr 290 295 300 Leu Tyr Gln Asn Gln Glu Gln Ala Arg Glu Ser Ala Arg Gln Tyr Ala 305 310 315 320 Leu Thr Ile Asp Glu Ile Ala His Lys Thr Pro Ser Met Ser Leu Pro 325 330 335 Glu Ala Ser Asp Asn Glu Gly Arg Thr Arg Ala Ala Leu Thr Glu Gln 340 345 350 Asn Arg Leu Ile Asp Glu Gln Ala Ser Arg Val Lys Ser Leu Gln Glu 355 360 365 Lys Ile Ala Gly Tyr Gln Tyr Val Leu Ala Asn Pro Gly Trp Thr Thr 370 375 380 Gly Asp Gly Phe Met Ile Asn His Leu Thr Ser Val Lys Thr Val Thr 385 390 395 400 Glu Gly Leu Ala Gln Ala Thr Glu Gln Leu Ala Val Glu Gln Ser Arg 405 410 415 Leu Ala Gln Met Gln Glu Lys Ala Gln Ser Ile Gln Asp Val Leu Ala 420 425 430 Gly Leu Glu Asp Arg Arg Val Ala Leu Ile Arg Gln Gln Ala Ala Glu 435 440 445 Gln Asn Lys Val Tyr Gln Ser Met Leu Val Met Asn Gly Gln His Thr 450 455 460 Glu Phe Asn Arg Leu Leu Gly Leu Gly Asn Glu Leu Leu Gln Gln Arg 465 470 475 480 Gln Gly Leu Val Asn Val Pro Leu Arg Leu Pro Gln Ala Thr Leu Asp 485 490 495 Asp Lys Gln Gln Ser Ala Leu Thr Lys Thr Glu Arg Glu Leu Ala Leu 500 505 510 Ser Arg Leu Lys Gly Glu Glu Lys Glu Arg Val Arg Leu Gly Tyr Ala 515 520 525 Ala Asp Asp Leu Gly Phe Val Gly Asp Pro Tyr Gln Glu Ala Arg Gln 530 535 540 Arg Tyr Ile Ser Asn Ala Leu Glu Ala Trp Arg Asn Asn Glu Ala Asn 545 550 555 560 Lys Pro Lys Ser Arg Gly Gly Lys Ser Glu Thr Glu Lys Ala Glu Asp 565 570 575 Ser Phe Ser Arg Leu Leu Lys Gln Gln Lys Glu Gln Leu Ala Leu Val 580 585 590 Gly Gln Asn Thr Glu Leu Ala Lys Leu Lys Tyr Gln Thr Ala Leu Gly 595 600 605 Glu Leu Lys Thr Leu Thr Glu Met Gln Lys Gln Glu Leu Leu Arg Asn 610 615 620 Ala Thr Leu Ile Asp Gln Gln Lys Ile Arg Glu Gln Leu Arg Ser Arg 625 630 635 640 Glu Glu Thr Leu Lys Asn Glu Asn Ala Ala Ala Arg Ala Ser Asn Asp 645 650 655 Ala Glu Leu Leu Gly Tyr Gly Gln Gly Glu Arg Ala Arg Glu Arg Met 660 665 670 Arg Glu Leu Gln Gln Ile Arg Asp Ser Phe Arg Gln Lys Asp Ala Asp 675 680 685 Leu Gln Ser Gln Tyr Gln Thr Gly Asp Ile Ser Glu Asp Phe Tyr Arg 690 695 700 Gln Ala Leu Ala Gln Asn Ala Gln Tyr Leu Ser Glu Arg Leu Lys Asp 705 710 715 720 Gln Ala Val Phe Tyr Ala Glu Ser Asp Val Gln Arg Ala Asp Trp Gln 725 730 735 Lys Gly Leu Gln Glu Gly Phe Ser Asn Trp Val Asp Asn Ala Ser Asp 740 745 750 Tyr Ala Ser Gln Ala Ala Gln Leu Ala Thr Glu Gly Ile Ser Gly Met 755 760 765 Val Asn Asn Ile Thr Glu Met Leu Asn Gly Asn Lys Val Glu Trp Arg 770 775 780 Ser Trp Ala Ser Ser Val Leu Gln Glu Ile Ser Lys Val Leu Met Asn 785 790 795 800 Ala Ala Ile Val Asn Gly Ile Lys Thr Ala Ala Asn Gly Met Ser Gly 805 810 815 Ala Gly Gly Phe Leu Gly Ser Ile Gly Asp Trp Leu Gly Gly Ala Val 820 825 830 Ala Asn Ala Lys Gly Gly Val Tyr Thr Ser Ala Asn Leu Ser Ala Tyr 835 840 845 Ser Asn Ser Ile Val Asp Thr Pro Thr Tyr Phe Ala Phe Ala Lys Gly 850 855 860 Ala Gly Leu Met Gly Glu Ala Gly Pro Glu Ala Ile Met Pro Leu Thr 865 870 875 880 Arg Ala Ala Asp Gly Ser Leu Gly Val Arg Ala Val Gly Ser Met Asn 885 890 895 Gly Ser Ala Gly Leu Val Tyr Ser Pro Val Tyr His Ile Ala Ile Gln 900 905 910 Asn Asp Gly Ala Asn Gly Gln Ile Gly Pro Glu Ala Ala Gly Ser Leu 915 920 925 Val Gln Leu Ile Asp Gln Arg Val Gln Ala Val Met Leu Ser Met Arg 930 935 940 Arg Asp Gly Gly Met Leu Ser Gly * 945 950 <210> 538 <211> 114 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33888..34229) <400> 538 Val Ala Glu Ile Lys Thr Leu His Leu Val Pro Arg Glu Gly Met Gln 1 5 10 15 Val Ser Glu Lys Pro Ser Val Val Arg Val Arg Phe Gly Asp Gly Tyr 20 25 30 Glu Gln Arg Arg Pro Thr Gly Leu Asn Pro Gln Leu Lys Thr Phe Gln 35 40 45 Ala Val Phe Arg Val Thr Asp Glu Ser Thr Arg Arg Trp Leu Asp Glu 50 55 60 Phe Leu Ser Trp His Gly Gly Tyr Arg Ala Phe Leu Trp Arg Pro Pro 65 70 75 80 Lys His Asn Arg Thr Val Arg Gly Val Cys Arg Glu Trp Ser Val Thr 85 90 95 Asp Asn Ala Arg Tyr Ser Asp Phe Ser Cys Thr Ile Glu Gln Val Val 100 105 110 Asn * <210> 539 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34229..34927) <400> 539 Met Gln Asn Ile His Glu Glu Ser Leu Asn Glu Ser Val Lys Ser Glu 1 5 10 15 Gln Ser Pro Arg Val Val Leu Trp Glu Ile Asp Leu Thr Val Gln Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Leu Asn Glu Lys Gly Glu Ala 35 40 45 Val Thr Trp Gln Gly Arg Gln Tyr Gln Val Tyr Pro Ile Asp Gly Ser 50 55 60 Gly Phe Glu Met Asn Gly Lys Gly Ser Ser Ala Arg Pro Ser Leu Thr 65 70 75 80 Val Ser Asn Leu Phe Gly Leu Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Ala Thr Val Val Arg Arg Arg Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Ala Gly Asn Pro Glu Ala Asp Pro Glu 115 120 125 Gln Glu Leu Arg Asp Arg Trp Val Val Glu Gln Met Ser Glu Leu Thr 130 135 140 Ala Met Thr Ala Ser Phe Val Leu Ala Thr Pro Thr Glu Thr Asp Gly 145 150 155 160 Ala Leu Phe Pro Gly Arg Ile Met Leu Ala Asn Thr Cys Met Trp Asp 165 170 175 Tyr Arg Gly Asp Glu Cys Gly Tyr His Gly Pro Ala Val Ala Asp Glu 180 185 190 Phe Asp Asn Pro Thr Thr Asp Ile Arg Lys Asp Arg Cys Ser Lys Cys 195 200 205 Met Arg Gly Cys Glu Met Arg Gly Met Val Ala Asn Phe Gly Gly Phe 210 215 220 Leu Ser Ile Asn Lys Leu Ser Gln * 225 230 <210> 540 <211> 85 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34944..35198) <400> 540 Met Thr Lys Val Arg Asp Ile Ala Pro Tyr Ser Val Arg Met Pro Asp 1 5 10 15 Ser Leu Lys Arg Asp Leu Thr Ile Arg Ala Ser Lys Asn Gly Arg Ser 20 25 30 Leu Asn Ser Glu Ile Val Met Ile Leu Gln Ala Ala Ile Asp Glu Glu 35 40 45 Lys Ser Pro Arg Ser Ile Glu Gly Phe Ala Gln Gln Glu Ser Glu Lys 50 55 60 Phe Arg Glu Ala Leu Leu Lys Thr Leu Ser Ser Met Tyr Gly Glu Asp 65 70 75 80 Lys Lys Pro Thr * <210> 541 <211> 293 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35721..36599) <400> 541 Met Lys Ser Ile Ala Lys Ala Gln Asn Asp Phe Thr Ile Phe Lys Phe 1 5 10 15 Gly Asp Ser Glu Ile Arg Val Ile Asn Lys Cys Gly Glu Pro Trp Phe 20 25 30 Val Ala Lys Asp Val Cys Asp Ala Leu Ala Leu Thr Asn Ser Arg Lys 35 40 45 Ala Leu Thr Ala Leu Asp Asp Asp Glu Lys Gly Val Thr Leu Ser Tyr 50 55 60 Thr Leu Gly Gly Glu Gln Asn Leu Ser Ile Val Ser Glu Ser Gly Met 65 70 75 80 Tyr Thr Leu Val Leu Arg Cys Arg Asp Ala Val Asn Lys Gly Ser Val 85 90 95 Pro His Lys Phe Arg Lys Trp Val Thr Ala Glu Val Leu Pro Ser Ile 100 105 110 Arg Lys His Gly Glu Tyr Val Lys Gly Lys Lys Thr Thr Val Glu Glu 115 120 125 Arg Thr Pro Leu Arg Asp Ala Val Asn Met Leu Val Gly Lys Lys Gly 130 135 140 Leu Arg Asn Asp Asp Ala Tyr Asn Met Val His Gln Arg Phe Gly Ile 145 150 155 160 Asp Ser Ile Asp Glu Leu Ser Ile Glu Gln Ile Pro Leu Ala Val Glu 165 170 175 Tyr Ile His Arg Val Val Leu Glu Gly Glu Phe Ile Gly Lys Gln Glu 180 185 190 Lys Ser Thr Asn Glu Leu Ser Ala Lys Glu Ala Asn Ser Leu Val Trp 195 200 205 Leu Trp Asp Tyr Ala Asn Arg Ser Gln Ala Leu Phe Arg Glu Leu Tyr 210 215 220 Pro Ala Leu Lys Gln Ile Gln Ser Asn Tyr Ser Gly Arg Cys Tyr Asp 225 230 235 240 Tyr Gly His Glu Phe Ser Tyr Val Ile Gly Met Ala Arg Asp Val Leu 245 250 255 Ile Asn His Thr Arg Asp Val Asp Ile Asn Glu Pro Asp Gly Pro Thr 260 265 270 Asn Leu Ser Ala Trp Met Arg Leu Lys Asn Lys Glu Leu Pro Pro Ser 275 280 285 Pro His His Tyr * 290 <210> 542 <211> 246 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36653..37390) <400> 542 Met Leu Tyr Ser Asn Ile Leu Ala His Ala Arg Arg Cys Ala Pro Ala 1 5 10 15 Glu Ser Cys Gly Phe Val Val Arg Thr Pro Glu Gly Glu Arg Tyr Phe 20 25 30 Pro Cys Val Asn Ile Ser Gly Glu Pro Glu Asp Tyr Phe Arg Met Ser 35 40 45 Pro Glu Asp Trp Leu Arg Ala Glu Met Gln Gly Glu Ile Val Ala Leu 50 55 60 Val His Ser His Pro Gly Gly Leu Pro Trp Leu Ser Glu Ala Asp Arg 65 70 75 80 Arg Leu Gln Ile Lys Ser Ala Leu Ser Trp Trp Leu Val Cys Arg Gly 85 90 95 Glu Ile His Lys Phe Arg Cys Val Pro His Leu Thr Gly Arg Arg Phe 100 105 110 Glu His Gly Val Thr Asp Cys Tyr Thr Leu Phe Arg Asp Ala Tyr His 115 120 125 Leu Ala Gly Ile Asp Met Pro Asp Phe Glu Arg Glu Asp Asp Trp Trp 130 135 140 Arg Asn Gly Gln Asn Leu Tyr Leu Asp Asn Met Ala Val Thr Gly Phe 145 150 155 160 Tyr Arg Val Pro Leu Ser Ser Ala Gln Ala Gly Asp Ile Leu Leu Cys 165 170 175 Cys Phe Gly Ala Ser Val Ala Asn His Ala Ala Ile Tyr Cys Gly Asn 180 185 190 Gly Glu Leu Leu His His Leu Pro Glu Gln Leu Ser Lys Arg Glu Arg 195 200 205 Tyr Ser Glu Lys Trp Gln Arg Arg Thr His Ser Ala Trp Arg His Arg 210 215 220 His Trp His Val Ser Ala Phe Thr Gly Ile Tyr Asn Asp Leu Ala Ala 225 230 235 240 Ala Ser Ala Cys Thr * 245 <210> 543 <211> 95 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37288..37572) <400> 543 Met Ala Thr Thr Asn Ala Phe Ser Leu Ala Ser Pro Pro Leu Ala Arg 1 5 10 15 Ile Cys Leu His Gly Asp Leu Gln Arg Phe Gly Arg Arg Leu Ser Leu 20 25 30 Tyr Val Asn Thr Ala Ala Glu Ala Ile Arg Ala Leu Ser Leu Gln Met 35 40 45 Pro Gly Phe Arg Arg Gln Met Asn Glu Gly Trp Tyr Gln Thr Arg Ile 50 55 60 Pro Thr Ala Ser Gln Asn Arg Ser Pro Ala Pro Val Phe Val Val Met 65 70 75 80 Ser Gly Glu Tyr Leu Leu Asp Lys Lys Glu Glu Ile Ile Gln * 85 90 <210> 544 <211> 783 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37694..40042) <400> 544 Met Leu Pro Thr Thr Asn Ile Ser Val Asn Ser Gly Val Ile Ser Phe 1 5 10 15 Glu Ser Pro Val Asp Ser Pro Ser Asn Glu Asp Val Glu Val Ala Leu 20 25 30 Glu Lys Trp Cys Ala Glu Gly Glu Phe Ser Glu Asn Arg His Glu Val 35 40 45 Ala Ser Lys Ile Leu Asp Val Ile Ser Thr Asn Gly Glu Thr Leu Ser 50 55 60 Ile Ser Glu Pro Ile Thr Thr Leu Pro Asp Leu Leu Pro Gly Ser Leu 65 70 75 80 Lys Glu Leu Val Leu Asn Gly Cys Thr Glu Leu Lys Ser Ile Asn Cys 85 90 95 Leu Pro Pro Asn Leu Ser Ser Leu Ser Met Val Gly Cys Ser Ser Leu 100 105 110 Glu Val Ile Asn Cys Ser Ile Pro Glu Asn Val Ile Asn Leu Ser Leu 115 120 125 Cys His Cys Ser Ser Leu Lys His Ile Glu Gly Ser Phe Pro Glu Ala 130 135 140 Leu Arg Asn Ser Val Tyr Leu Asn Gly Cys Asn Ser Leu Asn Glu Ser 145 150 155 160 Gln Cys Gln Phe Leu Ala Tyr Asp Val Ser Gln Gly Arg Ala Cys Leu 165 170 175 Ser Lys Ala Glu Leu Thr Ala Asp Leu Ile Trp Leu Ser Ala Asn Arg 180 185 190 Thr Gly Glu Glu Ser Ala Glu Glu Leu Asn Tyr Ser Gly Cys Asp Leu 195 200 205 Ser Gly Leu Ser Leu Val Gly Leu Asn Leu Ser Ser Val Asn Phe Ser 210 215 220 Gly Ala Val Leu Asp Asp Thr Asp Leu Arg Met Ser Asp Leu Ser Gln 225 230 235 240 Ala Val Leu Glu Asn Cys Ser Phe Lys Asn Ser Ile Leu Asn Glu Cys 245 250 255 Asn Phe Cys Tyr Ala Asn Leu Ser Asn Cys Ile Ile Arg Ala Leu Phe 260 265 270 Glu Asn Ser Asn Phe Ser Asn Ser Asn Leu Lys Asn Ala Ser Phe Lys 275 280 285 Gly Ser Ser Tyr Ile Gln Tyr Pro Pro Ile Leu Asn Glu Ala Asp Leu 290 295 300 Thr Gly Ala Ile Ile Ile Pro Gly Met Val Leu Ser Gly Ala Ile Leu 305 310 315 320 Gly Asp Val Lys Glu Leu Phe Ser Glu Lys Ser Asn Thr Ile Asn Leu 325 330 335 Gly Gly Cys Tyr Ile Asp Leu Ser Asp Ile Gln Glu Asn Ile Leu Ser 340 345 350 Val Leu Asp Asn Tyr Thr Lys Ser Asn Lys Ser Ile Leu Leu Thr Met 355 360 365 Asn Thr Ser Asp Asp Lys Tyr Asn His Asp Lys Val Arg Ala Ala Glu 370 375 380 Glu Leu Ile Lys Lys Ile Ser Leu Asp Glu Leu Ala Ala Phe Arg Pro 385 390 395 400 Tyr Val Lys Met Ser Leu Ala Asp Ser Phe Ser Ile His Pro Tyr Leu 405 410 415 Asn Asn Ala Asn Ile Gln Gln Trp Leu Glu Pro Ile Cys Asp Asp Phe 420 425 430 Phe Asp Thr Ile Met Ser Trp Phe Asn Asn Ser Ile Met Met Tyr Met 435 440 445 Glu Asn Gly Ser Leu Leu Gln Ala Gly Met Tyr Phe Glu Arg His Pro 450 455 460 Gly Ala Met Val Ser Tyr Asn Ser Ser Phe Ile Gln Ile Val Met Asn 465 470 475 480 Gly Ser Arg Arg Asp Gly Met Gln Glu Arg Phe Arg Glu Leu Tyr Glu 485 490 495 Val Tyr Leu Lys Asn Glu Lys Val Tyr Pro Val Thr Gln Gln Ser Asp 500 505 510 Phe Gly Leu Cys Asp Gly Ser Gly Lys Pro Asp Trp Asp Asp Asp Ser 515 520 525 Asp Leu Ala Tyr Asn Trp Val Leu Leu Ser Ser Gln Asp Asp Gly Met 530 535 540 Ala Met Met Cys Ser Leu Ser His Met Val Asp Met Leu Ser Pro Asn 545 550 555 560 Thr Ser Thr Asn Trp Met Ser Phe Phe Leu Tyr Lys Asp Gly Glu Val 565 570 575 Gln Asn Thr Phe Gly Tyr Ser Leu Ser Asn Leu Phe Ser Glu Ser Phe 580 585 590 Pro Ile Phe Ser Ile Pro Tyr His Lys Ala Phe Ser Gln Asn Phe Val 595 600 605 Ser Gly Ile Leu Asp Ile Leu Ile Ser Asp Asn Glu Leu Lys Glu Arg 610 615 620 Phe Ile Glu Ala Leu Asn Ser Asn Lys Ser Asp Tyr Lys Met Ile Ala 625 630 635 640 Asp Asp Gln Gln Arg Lys Leu Ala Cys Val Trp Asn Pro Phe Leu Asp 645 650 655 Gly Trp Glu Leu Asn Ala Gln His Val Asp Met Ile Met Gly Ser His 660 665 670 Val Leu Lys Asp Met Pro Leu Arg Lys Gln Ala Glu Ile Leu Phe Cys 675 680 685 Leu Gly Gly Val Phe Cys Lys Tyr Ser Ser Ser Asp Met Phe Gly Thr 690 695 700 Glu Tyr Asp Ser Pro Glu Ile Leu Arg Arg Tyr Ala Asn Gly Leu Ile 705 710 715 720 Glu Gln Ala Tyr Lys Thr Asp Pro Gln Val Phe Gly Ser Val Tyr Tyr 725 730 735 Tyr Asn Asp Ile Leu Asp Arg Leu Gln Gly Arg Asn Asn Val Phe Thr 740 745 750 Cys Thr Ala Val Leu Thr Asp Met Leu Thr Glu His Ala Lys Glu Ser 755 760 765 Phe Pro Glu Ile Phe Ser Leu Tyr Tyr Pro Val Ala Trp Arg * 770 775 780 <210> 545 <211> 1134 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40633..44034) <400> 545 Met Lys Ile Thr Asn Tyr Ile Leu Pro Thr Ser Arg Thr His Gly Ser 1 5 10 15 Phe Ser Thr Ile Lys Ser Trp Asp Thr Met Asn Tyr Ile Lys His Leu 20 25 30 Ile Arg His Thr Asn Asp Pro Ile Phe Glu Glu Gln Phe Tyr Lys Ile 35 40 45 Thr Gln Ser His Ile Asp Phe Asp Lys Arg Ala Lys Asp Glu Lys Asn 50 55 60 Asp Thr Ile Asn Ile Tyr Asp Asn Phe Phe Tyr Ser Ser Asn Asp Asp 65 70 75 80 Leu Asp Ser Lys Ile Arg Ser Met Leu Asn Asn Leu Tyr Glu Lys Ser 85 90 95 Leu Thr Phe Arg Arg Ile Ile Asn Tyr Tyr Val Lys Glu Ile Asn Leu 100 105 110 Ser Asp Tyr Gly Phe Leu Lys Cys Lys Ile Leu Pro Ala Tyr Ala Tyr 115 120 125 Asn Tyr Glu Met Glu Asn Asp Ala Pro Pro Lys Ile Leu Ile Pro Ile 130 135 140 Asp His Asn Leu Asn Phe Ile Asp Ala Lys Tyr Asn Gly Glu Thr Tyr 145 150 155 160 Arg Gly Asn Glu Glu Phe Ala Ile Asn Leu Phe Leu Gln His Ile Leu 165 170 175 His Asn Asp Ile Gln Glu Gln Thr Ser Ile Asp Leu Tyr Thr Ser Ile 180 185 190 Ile Asn Lys Glu Leu Asp Ser Asn Arg Lys Ser Tyr Asn Asn Glu Ile 195 200 205 Phe Asn Asn Phe Ser Phe Asp Lys Ser Val Lys Leu Asn Ser Tyr Asn 210 215 220 Tyr Ile Ala Asp Asp Ile Glu Gln Val Ile Asp Lys Gly Ser Lys Val 225 230 235 240 Gln Leu Glu Val Tyr Asn Leu Leu Ser Glu Glu Lys Ile Phe Glu His 245 250 255 Lys Ile Met Asn Asn Trp Thr Arg Ser Ile Lys Asn Ile Leu Thr Thr 260 265 270 Tyr Leu Phe Met Ser Ser Gly Ala Val Thr Ala Arg Asn Val Gln Thr 275 280 285 Phe Ser Pro Thr Ile Asn Asn Glu Ser Arg Ile Arg Leu Pro Arg Ala 290 295 300 Leu Pro Val Gly His Pro Tyr Pro Glu Glu His Lys Ala Ser Gly Phe 305 310 315 320 Ser Pro Phe Met Met Gly Gly Leu Ser Gly Asp Ile Leu Pro Glu Ile 325 330 335 Leu Thr Gly Asn Gly Pro Ser Ile Phe Phe Asn Gly Lys His Asn Asn 340 345 350 Gln His Asp Gly Ala Phe Gly Lys Ile Ile Asp Phe Thr Gln Asn Gly 355 360 365 Asn Lys Ile Ser Ala Lys Asp Lys Glu Ile Ile Lys Arg Tyr Ile Phe 370 375 380 Asp Lys Ile Asn Val Leu Ile Lys Glu Tyr Phe Ile Arg Thr Gly Lys 385 390 395 400 Asn Ser His Thr Pro Phe Glu Val Phe Ile Lys Glu Arg Leu Phe Asn 405 410 415 Gln Tyr Asp Ile Phe Lys Thr Leu Ala Arg Asp Ile Leu Ala His Pro 420 425 430 Leu Val Ile Tyr Asp Ala Gly Tyr Lys Asn Tyr His Glu Ser Leu Asn 435 440 445 Ala Ala Ile Ala Ile Asn Ser Arg Pro Leu Gln Glu Ile His Tyr Gly 450 455 460 Asp Val Leu Tyr His Tyr His Lys Asn Asp Ile Ser Leu Gly Val Asp 465 470 475 480 Thr Leu Tyr Gly Arg Glu Ser Phe Asp Ile Val Leu Asp Ala Met Asn 485 490 495 Val Tyr Arg Lys Ser Lys Lys Met Arg Val Ile Ser Asn Asn Glu Met 500 505 510 Lys Lys Ser Ile Lys Ile Ser Glu Leu Val Ile His Asn Ile Ile Lys 515 520 525 Lys Gly Leu Thr Asn Cys Leu Leu Lys Lys Asp Val Leu Asn Ala Arg 530 535 540 Tyr Asp Leu Ile Arg Asp Ile Leu Arg Tyr Ser Leu Asn Ile Arg Gln 545 550 555 560 Gly Ile Lys His Asp Asp Val Asn Arg Ile Ala Glu Asn Ile Ile Lys 565 570 575 Lys Tyr Gly Ile Thr Glu Gly Met Asn Pro Lys Pro Arg Asn Ala Arg 580 585 590 Ile Ser Lys Glu Leu Leu Leu Leu Ala Val Asp Arg Gln Ile Glu Trp 595 600 605 Ala Lys Lys His Phe Ile Thr Lys Asp Val Leu Glu Asn Val Val Ser 610 615 620 Lys Cys Asp Leu Ser Ser Ile Phe Asn Val Asn Lys Val Leu Gln Asn 625 630 635 640 Thr Ile Leu Glu Phe Val His Glu Ile Asn Asn Ile Ser Ser Ala Arg 645 650 655 Trp Met Ser Lys Ser Glu Lys Asn Asn Lys Gln Lys Glu Ala Ile Glu 660 665 670 Lys Phe Lys Lys Glu Val Ser His Met Asn Gly Gly Gln Gln Phe Ile 675 680 685 Trp Gly Phe Asp Lys Val Ile Gln Glu Gly Leu Ser Gly Leu Ile Glu 690 695 700 Leu Ser Ile Asp Ile Asn Asp Ser Thr Asn His Arg Asp Lys Ser Ser 705 710 715 720 Leu Ser Pro Asp Gly Arg Ala Val Leu His Phe Leu Gly Thr Ile Trp 725 730 735 Asn Met Ala Met Gly Ala Val Pro Gly Tyr Asn Ala Leu Ser Gly Val 740 745 750 Ser Ser Ile Leu His Ser Ala Ile Val Lys Glu Ser Ser Asn Ile Cys 755 760 765 Asp Tyr Ile Gln Gly Ala Val Arg Ile Gly Met Asp Phe Val Pro Gly 770 775 780 Thr Arg Ser Asp Leu His Ser Arg Ser Leu Gln Ile Lys Tyr Glu Ala 785 790 795 800 Leu Lys His Ile Glu Lys Asn Ile Asn Asp Asn Ile Ile Tyr His Pro 805 810 815 Ser Asn Asn Ala Asn Phe Tyr Ser Val Ile Glu Ser Ile Asp Gly Asn 820 825 830 Asp Phe Ile Tyr Asn Glu Lys Gln Ser Lys Ile Leu Glu Met Lys Gln 835 840 845 Asp Arg Gly Gly Asn Arg Tyr Ser Ala Val Asp Leu Asn Ser Ser Lys 850 855 860 Tyr Gly Tyr Tyr Glu Lys Val Gly Gly Gly Phe Tyr Arg Tyr Ile Glu 865 870 875 880 Ser Phe Asn Pro Ile Ser Ser Glu Thr Pro Asn Lys Ile Val Tyr Lys 885 890 895 Gly Glu Ser Val Asp Leu Thr Lys Glu Pro Asn Ser Glu Leu Tyr Ser 900 905 910 Gly Arg Tyr Ser Ile Asn Asn Lys Gln Val Asn Val Tyr Phe Phe Arg 915 920 925 Asp Ala Asp Gly Thr Phe Tyr Lys Ser Glu Gly Leu His Gly Gly Gly 930 935 940 Val Ile Arg Tyr Ile Asp Lys Pro Tyr Ser Gln Leu Arg Glu Gly Asp 945 950 955 960 Ile Gly Tyr Asp Glu Asp Leu Leu Asp Ile Tyr Asp Asp Ser Pro Val 965 970 975 Leu Glu Asp Thr Leu Pro Ala Leu Ser Ser Glu Ile Val Pro Thr Pro 980 985 990 Glu His Ser Ile Lys Gln Ile Tyr Ser Lys Ile Lys Glu Gly His Ile 995 1000 1005 Glu Leu Ser Asp Ser Asp Ile Ile Leu Cys Arg Gly Thr Thr Gly Ile 1010 1015 1020 Gln Ala Glu Asn Ile Val Glu Tyr Lys Thr Ala Gly Gly Leu Pro Asp 1025 1030 1035 1040 Ser Asn Pro Asn Val Lys Ala Pro Asp Glu Tyr Met Ala Gln Gln Gln 1045 1050 1055 Val Arg Ile Gly Arg Ile Leu Pro Glu Tyr Thr Ser Asp Leu Ser Val 1060 1065 1070 Ala Asp Arg Phe Ser Arg Glu His Tyr Leu Ile Val Val Lys Val Lys 1075 1080 1085 Ala Lys Tyr Ile Thr Arg Gly Ser Val Thr Glu Ser Gly Trp Val Ile 1090 1095 1100 Asp Lys Thr Ala Pro Val Glu Pro Leu Ala Ile Ile Asp Arg Thr Phe 1105 1110 1115 1120 Gly Met Lys Glu Asn Ile Ser Met Val Asn Ala Ser Lys * 1125 1130 <210> 546 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44021..44176) <400> 546 Met His Arg Asn Ser Phe Phe Thr Ile Tyr Val Leu Pro Pro Leu Val 1 5 10 15 Lys Thr Met Leu His Leu Gly Asp Val Ala Arg Gln Tyr Gly Val Asp 20 25 30 Arg Tyr Val Val Lys Tyr Thr Ser Val Asn Glu Leu Pro Leu Ser Ala 35 40 45 Ile Ser Ser * 50 <210> 547 <211> 150 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44203..44652) <400> 547 Met Thr Gly Gly Ile Ala Gln Lys Val Asn Asp Pro His Gly Ser Pro 1 5 10 15 Ser Glu Ser Cys Cys Phe Ile Arg Pro Leu Lys Pro Ser Val Ser Val 20 25 30 Ser Ile Ala Glu Asp Gln Leu Leu Leu Leu Ile Tyr Ser Val Phe Thr 35 40 45 Cys Pro Asp Glu Ile Leu Phe Asn His Asn Ile Asp Tyr Ile Glu Asn 50 55 60 Ile Phe Phe Ala Ile Ile Lys Asn Ile Tyr Met Trp Asn Arg Ser Ile 65 70 75 80 Leu Asp Gly Ser Leu Ser Thr Leu Val Tyr Leu Ile Phe Phe Leu Leu 85 90 95 Val Ser Leu Cys His Ala Asp Lys Ile Leu Cys Phe Ser Leu Phe Gly 100 105 110 Cys Cys Leu Tyr Tyr Asp Lys Ser Ile Trp Ile Cys Pro Tyr Ile Ser 115 120 125 Arg His Leu Leu Ser Leu Asn Pro Leu Gln Ala Arg Cys Arg Arg Tyr 130 135 140 Ser Arg Gly Glu Arg * 145 <210> 548 <211> 302 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44577..45482) <400> 548 Val Asp Ser Ala Arg Ala Leu Ile Ala Arg Gly Trp Gly Val Ser Leu 1 5 10 15 Val Ser Arg Cys Leu Arg Val Ser Arg Ala Gln Leu Tyr Val Ile Leu 20 25 30 Arg Arg Thr Asp Asp Trp Met Asp Gly Arg Arg Ser Arg His Thr Asp 35 40 45 Asp Thr Asp Val Leu Leu Arg Ile His His Val Ile Gly Glu Leu Pro 50 55 60 Thr Tyr Gly Tyr Arg Arg Val Trp Ala Leu Leu Arg Arg Gln Ala Glu 65 70 75 80 Leu Asp Gly Met Pro Ala Ile Asn Ala Lys Arg Val Tyr Arg Ile Met 85 90 95 Arg Gln Asn Ala Leu Leu Leu Glu Arg Lys Pro Thr Val Pro Pro Ser 100 105 110 Lys Arg Ala His Thr Gly Arg Val Ala Val Lys Glu Ser Asn Gln Arg 115 120 125 Trp Cys Ser Asp Gly Phe Glu Phe Cys Cys Asp Asn Gly Glu Arg Leu 130 135 140 Arg Val Thr Phe Ala Leu Asp Cys Cys Asp Arg Glu Ala Leu His Trp 145 150 155 160 Ala Val Thr Thr Gly Gly Phe Asn Ser Glu Thr Val Gln Asp Val Met 165 170 175 Leu Gly Ala Val Glu Arg Arg Phe Gly Asn Asp Leu Pro Ser Ser Pro 180 185 190 Val Glu Trp Leu Thr Asp Asn Gly Ser Cys Tyr Arg Ala Asn Glu Thr 195 200 205 Arg Gln Phe Ala Arg Met Leu Gly Leu Glu Pro Lys Asn Thr Ala Val 210 215 220 Arg Ser Pro Glu Ser Asn Gly Ile Ala Glu Asn Phe Val Lys Thr Ile 225 230 235 240 Lys Arg Asp Tyr Ile Ser Ile Met Pro Lys Pro Asp Gly Leu Thr Ala 245 250 255 Ala Lys Asn Leu Ala Glu Ala Phe Glu His Tyr Asn Glu Trp His Pro 260 265 270 His Ser Ala Leu Gly Tyr Arg Ser Pro Arg Glu Tyr Leu Arg Gln Arg 275 280 285 Ala Cys Asn Gly Leu Ser Asp Asn Arg Cys Leu Glu Ile * 290 295 300 <210> 549 <211> 54 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45644..45805) <400> 549 Met Ile Asp Val Leu Gly Pro Glu Lys Arg Arg Arg Arg Thr Thr Gln 1 5 10 15 Glu Lys Ile Ala Ile Val Gln Gln Ser Phe Glu Pro Gly Met Thr Val 20 25 30 Ser Leu Val Ala Arg Gln His Gly Val Ala Ala Ser Gln Leu Phe Leu 35 40 45 Trp Arg Lys Gln Tyr * 50 <210> 550 <211> 58 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46090..46263) <400> 550 Val Thr Ala Trp Thr Val Thr Ser Glu Lys Arg His Leu His Arg Ile 1 5 10 15 Val Tyr Arg Val Lys Tyr Phe Asn Phe Thr Thr Leu His Asp Tyr Asn 20 25 30 His Phe Cys Asp Phe Ile Glu Phe Lys His Lys Asn Ile Ile Met Asn 35 40 45 Thr Ser Gln Tyr Thr Gly Ser Ser Trp * 50 55 <210> 551 <211> 92 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46343..46618) <400> 551 Met Pro Phe Ser Ile Lys Asn Arg Phe Ser Ser Ser Gln Val His Tyr 1 5 10 15 Pro Glu Ile Ser Gly Pro Ile Lys Asp Lys Pro Ala Ser Lys Asn Cys 20 25 30 Ile Leu Thr Ser Thr Thr Cys Asn Val Asp Ser Tyr Thr Val Tyr Gln 35 40 45 Lys Lys Ala Cys Ser Phe Asp Met Arg Pro Pro Gly Ala Gly Glu Arg 50 55 60 Thr Pro Lys Leu Lys Leu Ser Val Thr Glu Met Thr Trp Leu Ser Lys 65 70 75 80 Thr Ile Glu Thr Glu Ile His Asn Thr Lys Glu * 85 90 <210> 552 <211> 454 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46679..48040) <400> 552 Met Leu Pro Thr Ser Gln Leu Arg Pro Thr Gly Thr Phe Cys Ser Tyr 1 5 10 15 Ser Ala Glu Thr Ser Ala Asp Ile Lys Ser Glu Ile Thr Pro Ile Gln 20 25 30 Ile Glu Glu Ala Arg Ala Ser Gly Arg Leu Tyr Ile Lys Asp Cys Asp 35 40 45 Ile Glu Tyr Leu Pro Gln Leu Pro Asn Glu Ile Thr Ser Val Thr Ile 50 55 60 Glu Asn Cys Asn Asn Leu Thr Thr Leu Thr Gly Leu Pro Val Asn Thr 65 70 75 80 Gln Asn Leu Ser Val Ile Asn Cys Glu Lys Leu Gln Ile Thr Asp Met 85 90 95 Pro Ser Thr Val Lys Asn Leu His Ile Glu Leu Thr Asp Ser Pro Phe 100 105 110 Ile His Phe Ile Ser Glu Gly Ile Glu Cys Leu Thr Val Cys His Cys 115 120 125 Tyr Ile Ser Gly Val Pro Glu Ser Val Arg Tyr Leu Glu Ile Lys Gly 130 135 140 Ser Ala Thr Asp Ser Ile Lys Asn Val Pro Asn Gly Leu Ser Ser Leu 145 150 155 160 Ser Ile Asn Ser Tyr Asn Pro Glu Asn Gln Ala Arg Ile Asp Asn Leu 165 170 175 Ile Ser Pro Ser Leu Lys Thr Leu Ser Leu Thr Gly Cys Ser Asn Ile 180 185 190 Ile Leu Pro Glu Lys Leu Pro Glu Ser Val Thr Ser Val Thr Ile His 195 200 205 Ala Glu Gln Lys Thr Thr Trp Asn Ile Gly Val Glu Gly Met Pro Asp 210 215 220 Gly Leu Asp Leu Asp Leu Gln Asn Val Leu Leu Ser Pro Asp Val Val 225 230 235 240 Lys Ala Lys Asn Ile Thr Phe Gln Gly Asn Ala Leu Asp Val Ala Leu 245 250 255 His Phe Arg Glu Gly Asp Ile Val Tyr Gly Leu Ser Ser Pro Arg Glu 260 265 270 Lys Leu Val Asn Ser Ile Lys Leu Val Asn Asp Phe Ser Lys Lys Asp 275 280 285 Ile Ile Thr Gln Asn Thr Leu Thr Asn Ala Val Trp Asp Pro Arg Thr 290 295 300 Pro Arg Lys Tyr Lys Gln Asp Pro Leu Ile Lys Arg Ala Leu Asn Glu 305 310 315 320 His Glu Arg Gly Ile Lys Phe Lys Gln His Leu Lys Asn His Asn Asn 325 330 335 Tyr Asn Val Thr Met Ala Asp Leu Ser Val Tyr Asn Arg Asp Lys Leu 340 345 350 Trp Ala Lys Thr Ser Lys Ala Gly Leu Glu Phe Gln Thr Leu Thr Arg 355 360 365 Asn Lys Thr Val Ile Phe Cys Ala Asp Glu Leu Val Asn Ser Leu Lys 370 375 380 Leu Ile Ala Asn Lys Ser Glu Gly Tyr Gly Gln Ser Ile Thr Ala Ser 385 390 395 400 Glu Leu Arg Trp Ile Tyr Arg Asn Lys Asp Asn Asn Gln Ile Met Lys 405 410 415 Asn Ile Lys Phe Tyr Leu His Gly Lys Glu Ile Pro Ala Glu Arg Ile 420 425 430 Leu Asp Thr Pro Glu Trp Lys Asp Tyr Arg Pro Lys Tyr Ser Gly Ser 435 440 445 Thr Tyr Lys Tyr Ser * 450 <210> 553 <211> 71 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48161..48373) <400> 553 Leu Ala Cys Phe Leu Leu Ser Ser Lys Gln His Ala Ser Ile His Lys 1 5 10 15 Ile Lys Gln Leu Gln Ser Asn Phe Gly Glu Arg Phe Phe Phe Ser Leu 20 25 30 Leu Ala Asn Arg Tyr Lys Lys Thr Thr Asn Gly Ile Lys Met Ser Asn 35 40 45 Pro Asn Pro Cys Met Thr Asp Trp Arg Lys Tyr Ser Gln Lys Leu Lys 50 55 60 Ser Thr Val Cys Trp Phe * 65 70 <210> 554 <211> 47879 <212> DNA <213> Escherichia coli O157:H7 <400> 554 acgcaacatt tttaaaaatc gacgaagatc gtccaggagc gccgtttttc aagggttgga 60 tagatgattc gtttaccatg tcgatgaact tcgacgaatt tcgccgataa aaagtgtccc 120 atacatgccc cattgatgcc ccataaacaa tatcaggaat tgacactggt tatccataca 180 gataaaaata acacctgtac ataactacag ttacaggagg gtgttatgcg tgttgagatc 240 tgtatcgcta aagaaaaaat cactaaaatg ccaaacggtg ctgtggatgc gttaaaggaa 300 gaattaaccc gacgcatcag taaacgttat gacgatgtag aggtgatcgt aaaagccacc 360 agcaacgatg gcctttctgt tacgcgcacc gccgataaag attcagctaa aacttttgtt 420 caggagacgc tgaaagatac ctgggagtct gctgacgagt ggtttgttcg ctaataaaca 480 cgtaaatcgg taacggctgg aaatcattca atactcgcac tatcgaaagt tcaccagcca 540 accgcgacac gctcttacat acgaagtgcc gcgctttcct taataatttt ttagcagtac 600 tgtgtaaata atgagcgacc taatccatgc atgacgcgta gtgcctattg tgcatctttc 660 tgcgtctctt tttactggac ccaagccaat gatgctggcg ataccattcc cgccaggccc 720 acttacaaca gtaaaattcg gagctctgcc tttacataca atacaatcta cctaacaaat 780 atcccccgga cattgcaaca caaaaaccgg agccggactc cggttttgtg aagctgtcgg 840 gttacttcat cccgccaata ttttcccacg tcccgtcagc acgcaggatt tgcagcggtc 900 ttaccacgca ctgtatctgc tttttatccg catccagtat caccacctgc gtgattaccc 960 tgtcctgctc cggaataata ccattctcat cggactccag gatgtctgcc ggccccagtc 1020 gcagttgtgc tgtaagcgac tgcccgtgtt cacggccatc atgctttccg caaccacaca 1080 gacgctgcat aagttttttt agtatattca tgtcattctc ctgttctgcc tgtatcactg 1140 cccacttcat ccagcccctt aacatcctgc cacggcccgt caccaaacct gacctgcaaa 1200 tgccgaaaca gcccctgaac ctgtgtggca tctttggggt caagaaaggt cagtccggtg 1260 atgagtgcgc catctgtatc cgggaaccag ccattgctgt ttgtctcaat aatgctcgcc 1320 ggccccagac gaaaacggat ttgtgtctcc cccgggtcgc ccttcggtcc ctgaggtccg 1380 gttgccccca ccgggccagc cgcacctgtt tctcctttcg gtccctgtgg gcctgccggg 1440 cctgccgcac cggtatctcc ctttggaccc tgtggacctg catttcccgt cagaccggtc 1500 tctccccgct ctcccctgtc acctttcggc ccctgcgggc ctgccggacc agcatcacct 1560 gccggtcccc gttcgccggt tgccccgaca gggccggtgt caccgcgctc tcccttatca 1620 cccttcggcc cctgaggacc cgcgggcccc tgttccccct ttggcccggg aggtcccacc 1680 acggtgggga ttcggtttac ggcctcttcc gccgctatcc tgctttgttc cgctgactgt 1740 gcgctttctg ctgactcccg ggctttttct gttgcggtcg ttgcatccct ggctgcatta 1800 ccggctgcac tttctgccgt ctttcttgac aattcagctt ctgctgcact ttgtgatgac 1860 tcactggctt tttgagcggc cgcagaagcc gaggacgagg acgcatcctc tgactgcttt 1920 gcagcggctg cactttctgc cgcctgccgg gctgactcca atgcatcccc tgctgaagtg 1980 tcagcatttg ccgcgctctc ttctgcctga ctggctgata tgccggcatt cctcgcggac 2040 gtctccgcct ctccggcatt cttcttcgcc tcctcagcgt gacgcgccgc ttcttccacc 2100 atcagttcaa aacgacgcag tgcctccggc cggacgtcat cctccgacat ggcaccgaga 2160 aaatcattca gcgtccccgg ttgagaatct tcatacacgg tgatggtccc ggcatgtgac 2220 ggcgggaacc cttccaccaa cagaataacg ctgtactgac cgtactcaac gtccatgctg 2280 taacgaccgg cttcatccgg attttcagag gccaccgtgt tcaccaccac cgtggcgctg 2340 ttacgtctgg ctttcagttg aatggtgcag ttctctaccg gttttcctgt gccgtctttc 2400 agtacacctg aaatctttac tgccatattc accccacaaa aaagcccgcc tgaaccggcg 2460 ggctgtcata acactgtgtt acctggctaa tcagaattta tagccgacac ccacgatgaa 2520 gccgtcagtg cgccagtcgc cactgccgga gccttcataa gcaatatcaa tggccacgga 2580 ttcggtcggg ttaaactgca cgccagctcc ccacgccaga gacgtgttgc tgtggcgacc 2640 gtcatcactt ccggtcagca catcgtgcgt tttccccttg ttgtcagtta cgcggagata 2700 atccccggag aaagtcgaca cacggctgta agccacaccc gccatcgcat acgcgctgaa 2760 ccattcattc acgcgtacag acggccccgc catcacgctg aaccagcggt tacgcacgga 2820 atcttcatgc cagcgggtat cgctgtagcg cgttttttgc tcatcctcag cattggcata 2880 actgaaggac gtaatcagcc ccagcgcgtc cataaactca taacggtatt tcacgttaat 2940 cccgttcaga tcatcactac cgggaacgtt cgtcgaggca tggagatacc ccgcgctcag 3000 cgtggactga tgttctgctg cactcgctgg cgtagcagcg gcgacctgcc agactactgc 3060 ggacaaaata acagcacata atttacgcat aattacctct cgcttttctg caataaaaaa 3120 ggcgccattt ctggcgcccg tatctgggtt ataaaattca gctaatcgtg atgcctgcag 3180 tggctttctt catcaccaca accagcaaat cgctgatact tgctgtggga taccagttat 3240 ttaccagcca tgctgacacc gaaaactcca gtgtcatgtg accgtgaccg gcaggcatat 3300 caataacacc actgtaaatc agcgtattat ccagcgcggt acggttataa atttcagcac 3360 cgtttttccg cactatcaga cggcatgagg agtaaatatc agtatgctct ttctcatgtt 3420 tagcgccgct gaatgccacc gccggaataa caatctgccg gtcaaacggc tgatcgtcat 3480 aaaccctgac ggtaatggtt cctgatggcc accgctccgg tgcacgggag tcccggggga 3540 aagctttgcc cactgtttta acgagatcgc cttcaatctg gttcgcggac aattttccca 3600 gaacccgaca gttctcgtta atcgtgacgt tgttgagcgt cccggagttc gcattcacgt 3660 taccgctgat atcggcattt ttcgccgtca gccgcccgtc cggtgtcagg gaaaatgccg 3720 gaggattacc gccgctggta atggtgggag ccgtcagata tttcaggaac acttcattca 3780 taaatatctg atcgccctga ccaacaaaca tcggctttgt gttgccattc gcaggattaa 3840 tcatcgcaat cctgtctgcc gccagcagca cctgactctg cattcctgct ggcgtattct 3900 caataccggc accgataccc gcaatataaa ggcgtccgtc ctgcatctgc tgcagtttca 3960 cggcccacat gctgttcagg ttattatttg tatcaacctg aactttctgt atctgctgga 4020 ttgccgcact ctgattttcc agttttttat tgacggtctg cgtgatttca ttgctgacat 4080 tcgtaatgga cgtcctgatt tcagccaggt ccggcgcaag ctgaccgtta tcaatctgcg 4140 tccacagctc ctgggccaga tgtgttttcc cgatttctcc tttgaaaaaa tccaggtaac 4200 cttccgcatc atcgctcgcc cgaccgacag cctccacgaa tgccgatttg ccaacagtat 4260 tcacactgcg gatataaaaa taataatcat ggcccggttt gatattgata ctggcagcta 4320 tccagtacag cgccgagcca agatagcggg ctgcggtttc aacctgcctg atatccgcaa 4380 tccgcttttc cgagaaccag aactcaaact gtaccgtcgg gtcataaacg gcaagatgcg 4440 gcgtggcggt tatctgaaaa tagcccggcg tcagctcaat ccgcgacggt gctgccggtg 4500 cggcaatccg gaaggtggtg gtggcaggtt caccctgctg gccatagctg tttatcgccc 4560 gcaccgtcag ggtgtattcc ccgagcggca ggccgctgaa acggtgctcc gtgtctgcgg 4620 tgatggcggt ggtcaccagt ctggcatccg ttcccttacc actggtcagg cgcagactga 4680 agcgcacgcc cttcaccacc cgcggcgtgt cccatttagc ctgcgccaga tactggccgt 4740 cagctgcact cacctccacc gtcaggtgct gtactgccgg tgggatgacg ctgttcaggg 4800 aacctgactg cggctcaaag cgggcaccgt tatccacgat ggcttctttt tccggtacgt 4860 gctgcaccgc cgtgatggca aaggtgccgt ccgtgttttc ccggacggag acacagcgga 4920 acaggcgacg gcacagtgac ggcagggaga gtccccacac cccgtatgtc tccacaccat 4980 caggcagggt actgacctgt atccggtccg gcgcggggtg tgcggtgatg tccacactca 5040 ccggcttacc gctgccgtta atcaggttca ccgtggcggc accggtctcc ggcagtgtca 5100 cctcacggtc cagcgtcagg gtgcggctgg cggcatcgat ggacaggaca cgtccgccgg 5160 tcatggtccc ggcatagtcg ttatcacaga tttcaataat gtcaccgggt gtgtgacgca 5220 gcccctgtga cccaagcgtg aaatccaccg tctgcgtttc cagcagtccg gtctttatca 5280 cccacagccc ggcacggtgg gcctgaccgc gactggtgca gccgaacgca tccatcttca 5340 gcaggttgcg tccgtagcgc agtatggctt ccgggtcttc caccagttcc gtggaggtct 5400 gccagccgtt ctgcgggtcg gtgtaattca cctccaccgc cgtgtggcgg tccttcaggg 5460 cgctgaagct gtagcgaaac cccacgccgt tatcatccac caccacatca ctgctggtgt 5520 aggccacacc acatctgacg gacggtcctg cacaaacgtc agcgtctgcc cgttccatac 5580 cggcatacag cgcatcgccg agcagaaatc actgagaacg tcccacgcct tacgctgttg 5640 tgacaggtac gcattgaaag tcatccgcgg ctctgtgccc ccgaaaccat ccgggaccgt 5700 ctggtcgcag tactgcgcaa tggcatacag cgcccacttg tccacatccg ccgcccccag 5760 gcgttttccc atgccgtagc gcgggtgagt cagcatgtcc cacaggcacc aggccgggtt 5820 gttgctgtat gccggtttca ggctgccgtc ccagatgccg ctgtacgtgc gtttttccgg 5880 gtcatagttt gacggtacct ggatgatgcg accgcggata tggtagttca ccgtcatctg 5940 ctgaccgcca aactgctccg catccacctg cagccccaca atcgccgtgt tcgggtagca 6000 ctgtttcaca tcgatgattt cggtgtatga cgaccacagc gttctgttct gcagctggtc 6060 cgtggtgctg tccgccgtct cccggaccat ccggatgtta aagggacggg gaggcagatt 6120 atccagaatc accgaagcga ggaactgtga ggtggtcttg ccgttaatgg tgacatcctt 6180 ttccgtcacc cagttaccgt tacgctgcag ctgaatcagc aggcggacgg atgccgggtt 6240 acggtcaccc tgtgaggtgg tctgcaccag tgactgcacc ccgaaggtaa cccgcaggcg 6300 gtcaatgttc gcggacgtaa tggtgcgcgt caccggcttt gccttcgtca cttccacgcc 6360 cagtgcggtt tcagagccgg atgactcaaa accttccggc ggtgtctgct cctgctcccc 6420 ggcgcgccag accgcggtca caccgtgtat cacgggattg ccgtccgtgt ccgtcagtgg 6480 ggttttgttc accagaatac tctgcagccc cttcaccgga ccttcaatcg gcccttcacc 6540 aatggcgtca atcacgctca tcatctgcgt ggacttaaga ttgtcctttg cctctaccgg 6600 cgtgtgcccc ttgccgcccc ctttacccac tctgtccccc tctcctgtct gatgtctgaa 6660 tctgtttatg ccagaaaaca acaggcaccc cggagggtgc ctgtgtcatg acggaataaa 6720 atttctgaaa ctcttcacat ttccggcaat tgcctgtagc cgcaataatg acgctgcatt 6780 acttttttga tgcctgaaaa ataactccat aacgttaatc ttcatcgttc tctcccgcag 6840 ctccgctaac tctgcgggat ttttttattt tcatccccgc ccgataacca ccactttccc 6900 gtctccgccc tcatcacggg tgctgatgtc ctgggatatc cgtcgtgaac caaccagcat 6960 ttcaccataa ggcaccggca tcgggttccc ctgggcaatc atgttatcca gtgacgaaaa 7020 atacgtgttc tgtttaccgt tatccgtcgc cctgtactcc ggtgtttttg ccttcggtgc 7080 cagcatctgg gccacaccgc ccagtatcat gctggcaccc agtgagaaca gcatcgtggt 7140 ggcagtcagc cctccggcac tcagggctgc gccccacaac gccatcgttg cgccggcggt 7200 gaagaaagag cccacgatgg ctgctgcccc cagcacaatc tgcagtccgc cctttccggc 7260 tccggccagt cgcggcacaa tatggatgac cgccccctca cccagaggtt cgtgaagacg 7320 ggcgtacacc gcctccggtg ccgtgtcctc accgcgaata cgtatctggt accagccttc 7380 gttcatctga cggcggaatc ccggcatctg cagcgacagg gcacggatgg cttccgctgc 7440 cgtgttcacg tacaggctga ggcggcggcc aaatcgttgc aaatccccgt gaaggcagat 7500 gcgtgccagt ggcggtgacg ccagacagaa tgcgttcgtc gttgccattt ttcagaatac 7560 ctctcccgtt tactcagttg ttcaggcaga tggtgaagca gttcaccgtt gccgcagtat 7620 atggcggcat gattggccac cgatgcgcca aagcagcaca gcaggatatc gcccgcctgt 7680 gcagaggaca ggggcacccg gtaaaaacca gtcgccgcca tattgtccag gtaaaggttc 7740 tgaccgttgc gccaccagtc atcctcacgc tcaaaatccg gcagcgttat ccccgccaga 7800 tggtatgcat cccggaacag ggtgtaacag tccgtcaccc cgtgctcaaa acgacgcccg 7860 gtcaggtgcg gcacacagcg gaatttatga atttcccccc ggcagaccag ccaccagggc 7920 agggcactct ttatctgcag ccgccggtcg gcctcgctca gccagggcag accaccaggg 7980 tggctgtgaa ccagcgccac aatctccccc tgcatctctg cctgcagcca gtcttccggc 8040 gcaatacgaa aatacgcctc cggctctgcg gagatattca cgcagggctg gtaccgttcg 8100 ccctccgggg tgcctatcac gaagccgcac gactccgcag gcgcacaccg ccgggcatgc 8160 accagaatcg ctgattcagt ctgtgtcata aaacaggatt tactgcgaaa gtttattgat 8220 ggaaaggaaa ccgccaaaat tagccaccat gccgcgcatc tcacacccgc gcatgcactt 8280 gctgcatctg tccttacgga tatccgtggt ggggttgtcg aactcatccg ccaccgcagg 8340 accgttatac ccgcattcat ctccccggta atcccacata caggtattcg ccagcataat 8400 gcgaccggga aacagcgctc cgtccgtctc cgtcggtgtt gccagcacaa acgaggctgt 8460 catggccgtc agctctgaca tctgctccac cacccagcgg tcgctcagct cctgctccgg 8520 gtccgcttcc ggattgcccg ccacaaaatt caccgcatcc agaaaacggg catacacccg 8580 gcggcggacc accgtggccc ccaccaggct ctgcaggtcc tccgccattc cggtgaccag 8640 accgaacaga ttcgacaccg tcagcgacgg gcgggcactg ctgcccttcc cgttcatctc 8700 aaaaccgctg ccgtcaatcg ggtatgcctg atattcccgc ccctgccagg taaccgcctc 8760 ccctttttca ttcagctcat tgcagaaaaa ataccgctca ccaccctgca ccgtcaggtc 8820 gatttcccag agcaccaccc gcggtgactg ctctgattta accgactcga tcaggctttc 8880 cccgtgaata tcctgcatca gttcaccacc tgcttaaact ccgcgctgaa ctcaacgcgc 8940 aacatcccga cccgcgcaga ccacccggca caggtcacct ttatctgccg gtatgcatag 9000 ggtggcttcc acaaaaatgc cttccagcct ccgtgctctg ccaggaatgc ctccagatgt 9060 cgggcctcct cccgggtcac ggaaagcgtc acacggtatg ttttcaggtc agcattcagc 9120 cccgccgcca tacgctgcga atacccgtca ccaaaacgca cttcacgcac cgatggctgc 9180 gagttcacct ccatatccgg cttcactttc cagcgaaatg ttttcatcgc ctgctccccg 9240 ataacatacc gccatcacgc aactgcagcc ggagctcatc ctgcgccccc ttgcgggcca 9300 tgtcatacac cgccttcatc agctgcggcc ccgcctgtcc gttggtgccg tcgttctgaa 9360 tcaccacgtg attgttctga ttaaaattaa tgccttccgt ccgccgcatc tgcgccggac 9420 ttccggcacc gcccacataa cccccttccg catagccccg catcaggcgg tacaggttgc 9480 cgacgccaat ccggctggtt gcctccttcg tgaagacaaa ctccccgcga tgaacaattc 9540 ccgcaggttc atatttaccc cccgtccccg taaatccccc ggtcgcgaaa tggaagttcg 9600 ccgccgcagc ctgaatggcc gtccccgtgg aggcagacgc accaccaccg aaagcaccgc 9660 caatggcgct gccgatacgc ccgacaatgc ccaccatggc ctgtttaagc aggatttctg 9720 tcatcatgga cagcaccgaa cgggtgaatc cccgccagtc tgcctctgca ccggtcagca 9780 tcgccgccat attctgtgca ataccgtcaa aggtctgcgt ggcagcactt ttaacctgcg 9840 aaaaactgtc cgtcgcactt tccgcccact cgccccagcc ggacttcagc ccggccatcc 9900 agcttccacg aagctgctcc tccgcagacc aggtgttctt cagtgccgat gtggccttcg 9960 ccagcgcagc cggattatca ccgtacacgt cccgaagacg ctgcgcttca gactcccgct 1002 0 gcgcctgacg gtcagtgaga ccgcgggctt ttgcgctgat ggcggcctgc ttcgcgctct 1008 0 gctgctcttc aaaccgcacc gcctgctgtg ccagctcatt caggcgtttc tggtattcaa 1014 0 ccttgtcgcc cagctcagcc agctggcgtt tgtactccag cgtctcgtct ttatgcgcca 1020 0 gcagggattt ttcctgctca gataactgtc gtttcgtggc agcctctttc aggaccgcat 1026 0 actgactttc cgccttccat aaatcacggc gctgccggct gattttctca ttcgcaccgc 1032 0 tgtgtttttc cagcgtcctg agctcagctt caagggcaag cagagcctct cttgcctgct 1038 0 cctcttccct ctccccggca gagcgcgttt tcggtgatgt atgcttttta cctgtcagct 1044 0 cttcagccag acggctgacg gcttcctgct gccccggacc tttgctgacg cctgttgcac 1050 0 gcgaacggtt gatgtacccc atttccccct ggcgtatacg cgcatcccgt tccgcaatgg 1056 0 attttctcag cgccagttca tcacgttttg ttttctcaat aaatacgcgg ttctcttctg 1062 0 ccagttcacc aaacaacgca ccaacgccgg gcacattctt tgtcgtttcc caggctgact 1068 0 gaataaattc agccagcgcc agatccccct gcacaagcag cagcttcacc tgttcaacgg 1074 0 ttcctgccac cacgtcagtg atcagactga gtgcccccag tgtatgatca cctatccatg 1080 0 cccatgcgtc agaagtccag gttttaacat cgtcccagat tttttccacc ggcgtggccg 1086 0 ctttatcaag ttgctccaga cgtgcattca tgacatccgc aaacagggac atcgcctccg 1092 0 tcaccgcagc ctgtttacct ttcgtgcgct caagctcatc aatatggcgt aactgggaaa 1098 0 cgctcaggaa gttatactgc tgattcaggg aggccagcgc cttcaccgga tctgctgcaa 1104 0 tcccttcaaa ggctttttcc accttcccgg catcgtcccc caccgtctgc agccatctct 1110 0 gagaggtttc ccccatgatc cgtagctgcc cggcggtata tttcccgctt tctgccagac 1116 0 gggccagatt ttctgccgcc tgtctgatac caccaccggc ttcatcgctg atcaccccgg 1122 0 ccattttcca caattctgcc gttgtggtgg cagcagcccc tccggtcagg gtcagtgaac 1128 0 gcaataaggc ccggtcagcc tgctctgcct gccaggcggc ggcagcaagc gcggccagta 1134 0 cggcaacccc gccacctgcc gccacacggg ccaccgacat aaatcgtccc agctcaccgg 1140 0 cattccgggc attttcagcc agtgcatttg ccgtatctga cagcgactcc tctgatgatt 1146 0 cagaggcatc cctgatcccg agaagttcct ccttcagcag ggtaagcagg ctgagcggtc 1152 0 caccgaatga atcgctgatc tgccccccct gctgcagcat gataaggaag ggattctgac 1158 0 caccggcaag ctgagtgaca atatccgtga actgtgcggg cagtgtgcgc atggcagcct 1164 0 tatactgtcc gactgatatc ccggcttttt gtgcagccag cgcctgtcgg ctcagactct 1170 0 gctcagcagc atcagcctgt tttctgaaag actgactgac tttcccggac atcaaatcag 1176 0 caagcgcact ggtttcaccc agctcttttt ttacccgcgc tgcctcttca gaaaaacggg 1182 0 cagaatccag tgtcagcacg gctgtcagat cggcaaaatt acctgccatc gtggtcacct 1188 0 cctgaaatgt cctctgatac catcaataac tgtcacaacc tccttccctc ctccccgaaa 1194 0 cggactccac cggcgaggcc cgccgccttc tgcatcagta catcattttc gtccggcgtc 1200 0 tccgcctgtc cttcctctgc ctccggagcg aacaggctga aatccgccgg atgcatatcc 1206 0 ggatcgcaaa aaaacaggct gagtacggcg tacatcagcc cggaaaaatg catatccagc 1212 0 tgggtatcct gaaaataatg cgtgcagtaa aaacgtcgcc agtcggcata ttcggtggat 1218 0 gtcatcccgg caagcatggc gcgccagtcg gctctcccca tctcacgcgc cagtttcagg 1224 0 acaaagttca gctcgccttc gaatgctttt ttgatgttac cggctcagtc gcttctgttt 1230 0 tcccggttgg ttcaggatcg gcatcgtgcc ggttatccag catacctgaa agataaagca 1236 0 cccggttcgt tgcctgattc agtgcatcag caggccatcc cagcatcact tcacggcgga 1242 0 tctgctgcat ctctgtctcc ggagaggcca gagtgccttt gagggaatgg gaatgccata 1248 0 gcgacatcgc cacaagcagg gatgccgttt ccagatatcg ctggttaatg tgcacgacat 1254 0 catgcttcgt tgtctcctgt tgttctgcgt ctgaaacaaa ctttatataa tcaaaccgct 1260 0 gcagcgcaga caattcggaa agcgtgacgg acacaccgtt atattcaaat tgttctgttt 1266 0 tcagaaacat gtattacctc cgtttaccct gcagcgcccg cttcagtaac ggtgacttca 1272 0 gccactgcgg cgaactgacc atttccgctc accacaggga tctgcacctt acctgtcgcc 1278 0 acgccgttta ccgtaattgt catatctttc acactaatgg tggctttcga cggatcggcg 1284 0 gaaaccgctc tgaacgtctt gtcggttgca ctttccggct caaaagaaac cgtcagggtg 1290 0 gttgttttcc cttttgccac cgtaccggat gtcggtgtca ccttaattgc agtggccggc 1296 0 gtaatttcgc tgcgttcttc cgccacggaa ggtttgccca cgttagtgac tttcaccgtg 1302 0 cgggtgatca cttctttcgc cgtcacggcc ttaccgatac tgctgaccca gccacggaac 1308 0 acatccaccg tgccatttgg gaaacggatt ttataggccc gcacatcccc gctttcaaac 1314 0 cagcctataa gccctttctg accttcttct cccggtttcc aggccagcgt aaaactggta 1320 0 tctcctgcag acttctgccc ctgcccggtc gcggtccagt ccgcgtcttc atcatccagg 1326 0 tagttatcat cgtagggttc tgccgtcatc tcgcccggcg tcagatcctt caccttagcc 1332 0 agtcgctgcc agtcatcgtc tgacaacggg tttgcataag catcaccctt gccgttgtaa 1338 0 acccacagag tggtaccggc accttttacc ggctcaaggg gatttggtgt tgccatatcg 1344 0 tcctcacatc tcgtaggtaa ttttccacag gagatctgcc gatccccaca tcataaactc 1350 0 atcatcccgg cggtagtcat acccctgaag attcatcttc agcagtaatg cactgagccc 1356 0 gggaactgcc tccagcgcag gaagaatttt ttcttccatc cacatatcca gtgccgagtc 1362 0 cggttctttt gccctgagaa aaacctcaat atgcagtgtc gcctcccagg ttccctcatc 1368 0 aacgaactcg tcagcagcag acgcatctgt caggtaaaca gcaacagcag gcagttcctg 1374 0 ttcatcaata aaaaccgggc gaccgtcaaa ccagctcacc ctctcagaaa tattttcttt 1380 0 cagggcagac agaactgccg cccgtatttc acggtgtttc atacaccctc ccagtcattt 1386 0 tcttttcagc accaggcgta actgatgcgt catggctttc atcatctgcg ccggtaattt 1392 0 ttcccggtac atccggtccc gttcacgttc aaaggtttct gccagcggtc cggcagtcgt 1398 0 aatcttcacc acttcgatcg gcagacggtg gcgtttcggc ctccctttgc tgtccgcgcc 1404 0 ggtggatgat gatgcccacg gcatacgctg catcacatgc cagcgtccgt tagccagccg 1410 0 ggtgataaag gcgtccggga tccgtctttt ccccacaatc agcacactgc cgcccccttt 1416 0 cagggccgca cgctgtcctt tctttctccg ttttctgcgg gaaagtcgaa cgcgggcctc 1422 0 ccccagtttg atggcgggca ggttgccggt attgatgtaa acctttgcgt aaaccttatc 1428 0 cggtcgtgcc ggacttaacc ggatgcgggc acggataaga cgacggggaa cggccagctc 1434 0 cctggcaact gaagaggccg ttttcgcaat aatggccccc gccactcggt tcagtgtcgt 1440 0 ggcagaggcc cggggaacgg cacggcgatc aattgcatcc agatttttca tggcctgcgc 1446 0 cagacctttt attgccatac tcattcctgt tcgacaaaaa tccggggttt accgttgtac 1452 0 gtgtcataac gggtcaccgt cagtgtgcgc cccgcaaaca caacaacatc atgacgggcc 1458 0 ggacggtacc gggctgaaaa caccaccagt gacaactggc tgcccgaaag cgcccccatc 1464 0 tccgcggact cttcctccgg catcacgtcg tacacgacgc cgttaatctc cgcctgtttg 1470 0 cccatcaccc gaacggtcgc cacgtccatc cggcaacaca ttcgcgtaaa cagatcagac 1476 0 attgattttt accgccacag tggcgctgtt tgcaggggca ttttcccagg ctacccccgc 1482 0 tgccaccgca ccgtctgcag ccagctgcac aaccccgtcc ttcagataaa ccaccgcgcc 1488 0 ggactgaatg tcgtcagcag actgtttggg cagcaggaac acgccttcgg caaaaccgtc 1494 0 accggcctca ccggcaggaa tatcggtaat ggccacggcc accatactgc cgaccaccac 1500 0 cgcagcaccg ctcaggatgg tctgatctcc ggcattcacc agttcaatgg tggtaccgtc 1506 0 ctgtacaaaa tttttcgcca taatgctgtt tctccggaca gcccctgtgg ggctgttttt 1512 0 caggcataaa aaaagccctt tcgggcagtg attgtgataa cgcggttatc aggccaccga 1518 0 cgaacgcacc agcccgcgcc agtcaagtgg tgccactccg gcatcaatac ggatttttgt 1524 0 ggcaatgccg tcagtggtga aaccttcctg ctgatcaatg tatggcgtgt ccacaccatc 1530 0 cagccaggcc acttcaatgg tgtcagtgcc ctgtgccgcc gccagatacc aggttttcgg 1536 0 gtctgccgca tcaagacgcg cttctgcaat cacctcagca aagttctgga tagggttaat 1542 0 gacaccggcg tttgcatccg cccctttcac actggccgat ttgatggtct ggttcgccac 1548 0 cgtctccagt gccaccggta ccagcataaa ggccggacgg atattcaggg cacgatcgcc 1554 0 ttctttctgc aggcgcatca tctgacgggc cgcatccagt ccggaaacgg agatcccccc 1560 0 ggtggcaata tttttgtgat cggcatggaa cagcgcctta ccgtcggaca gtttcgggtt 1566 0 atccgtcagc accttgtaga ccaggtcacc aatcgttgcc ttcgccgcac gccccatctt 1572 0 catcggcacg tccaccagca tattcagatc atcattgata atggcctggc gggtgatgga 1578 0 gaaaatctcc ccgtaagtgg ccagtgcaat ggtctccttg cgatctgagg tggtgatgta 1584 0 tttatactcc gccccctcac gaacctggcg cagagaacca aaaccgccca tccccacgcg 1590 0 atacgctgtt ttgaagtctg acaggcgtcc cttacgggtc cacttctgga aggtttcttc 1596 0 tgattcctcc cagccctgga tcagcccctt gttcgacaca tccagcagaa tattgccaaa 1602 0 atcagaggtg ctgtgcgtca gcgccagccc gaccatctgc atggggttat aactggccac 1608 0 cccaataccg cgctccgtca gtgacatgcg agcccattca cgcagggtca tcccgttata 1614 0 ggcgttatcc ttctcgacat tttcaaatcc ggcacgggcc agcatcgcct ggcggatccc 1620 0 gtcccccaca aaattgccgt ttccggcata aatatgggcc ggtgtatttt tgttggtcgg 1626 0 cgaggactcc ttgccctgaa ccgccccgga aatcctggag actaaactcc ctgagaaaga 1632 0 ggtaaacagg atgactaaaa atactcgttt ttcccccgaa gtccgtcagc gggcgattcg 1638 0 tatggttctg gaaagtcagg atgaatatga ctcacagtgg gcggcaattt gttccattgc 1644 0 cccaaagatt ggctgtacgt cggagactct gcgtgtctgg gttcgccagc atgagcggga 1650 0 taccgggggc ggtgatggtg ggctcaccag cgctgaacgt cagcgtctga aagagctgga 1656 0 acgtgaaaat cgtgaactgc gccgcagtaa cgatatcctt cgccaggctt ccgcttattt 1662 0 tgcgaaggcg gagttcgacc gcctctggaa aaaatgatgc cactgctgga taagctgcgt 1668 0 gagcagtacg gggtcggacc ggtatgcagc gaactgcata ttgccccgtc aacgtattac 1674 0 cattgtcagc aacagcgaca tcatccggat aaacgcagtg cccgtgcgca gcacgacgac 1680 0 tggctgaaga gagagataca gcgcgtatac gatgaaaatc atcaggtgta cggtgtgcgt 1686 0 aaagtctggc gtcagttgtt acgggaagga atcagggtgg ccagatgtac agtggcacgt 1692 0 ctcatggcgg ttatgggact tgccggtgtt ctccggggta aaaaggtccg tacgaccatc 1698 0 agccggaaag ccgttgccgc aggcgaccgc gtaaaccgtc agttcgtggc agaacgacct 1704 0 gaccagctgt gggtggctga ttttacttac gtcagcacat ggcagggctt cgtctatgtg 1710 0 gcgtttatca ttgatgtgtt tgccggatac atcgtggggt ggcgggtctc atcgtctatg 1716 0 gaaacgacat tcgtgctgga tgcgctggag caggcgttgt gggcccgtcg tccgtctggc 1722 0 accatccatc acagcgataa aggctctcag tatgtgtcac tggcctatac ggagcgacta 1728 0 aaagaagccg gattactggc atcaacaggg agtacaggcg actcgtatga caacgcgatg 1734 0 gctgagagca tcaatggtct ttacaaagcg gaggtaatac accgtaagag ctggaaaaac 1740 0 cgtgcagaag tggaactggc cacactaacg tgggtggact ggtataacaa tcgacgattg 1746 0 ctgggaaggc tgggccatac tcctccggca gaagcagaaa aagcttatta tgcttccatc 1752 0 ggaaacgatg atctggcagc ctgagttcac agataaaaca ctctccagga aacccggggc 1758 0 ggttcaccca tttcattcag cagacgttca cgggccattt ccagcgaaca gtcaggatca 1764 0 gccacgcact gtgcctgaag cgtctgatag cgaccgccga acatggcaaa cagatcgtta 1770 0 atgcctgaca tgcgggcttt ctgctcagcc ataacgcggg cgcgaatggt cgcctcatca 1776 0 gacactgccg gtaccggtga tggttctgtt accgccggtg cagggattgt cactgtggta 1782 0 tcacgcgggg cactgttgcg tggcggagta atcatgtttc ggatggattc cggcatcttt 1788 0 ttaaattcct ctgtacgttt tgactgaata catgccattg cctcaacagc gggtgtcacc 1794 0 tggtcagcaa atccgtgtgc cagacattcg gcaccggaca tccaggtttc atccgccagc 1800 0 atggcggcaa tttcatcggt ggtttttccg gttttctgcg cataggctgg caacagtacc 1806 0 gattcgactt tatccagcaa atcggcataa ctgcgcatat cctcagcatc cccgccactg 1812 0 aatccccatg gcttatggat catcatgaag gcattttccg gcataatgac cgtatcaccg 1818 0 gccatcgcaa tcacagatgc catcgaggcg gcaacgccat ccacatacac ggtaatggtc 1824 0 gccccctgat ttttcagggc attaaaaatg gcgatgcctt caaagacatc gccacccggt 1830 0 gaattgatat ggagattaat gtgggtgata tcacccagtg cattcagttc gctgacaaac 1836 0 tgcttcgcgg taactcccca gaaaccaatc tcgtcataaa tataaatatc cgcgtcaccc 1842 0 ggccccccag cttgcatcct gaaccaggat ttattcttca tgctggcttt cggtgtcgcg 1848 0 ctgatactgt cgttcagttc cggcactgtt gcctcctttg tcgttgacgg ggtcagtatc 1854 0 aaagaccagc cccagtctgc tgttttcatc aatttcagcc ttgcggcgac gtttgacctc 1860 0 atccggattg cgcccaccgg cacgcaccca gtcagattct gtcgctgcac caccccggat 1866 0 ctgaattctc caggcttcag cttccttaac cgggtcgatc cacggcatca ccggaccgga 1872 0 atacgtcgcg ttatatagcg ttttcatctc cacatccgcc ggaattttca gcagacctgc 1878 0 cgcaaccacc atattcagcc atgtccggta caccgggcgg gttaccgcgc caataaaaca 1884 0 gtcctgcagg atcaggtaac catccgtgga ctcgaccagc tcctgccgct gggcgctgta 1890 0 ggtgccgtta tagttacgcg ccgcactgga aaaactcaga cgactgcctg ctgccactgc 1896 0 acgcaactgg ccgttgcgga aagtttcaag gttgggattg ggacggtcag atttgaccat 1902 0 gccgatatcc tcgcccttgc gcaaatcgtc ataaataata cccggggtga tatggacttc 1908 0 ccgctcggtc tctttgatcc ccggatcttc atagtcctgt ccgtcacctt tacggatata 1914 0 cagtcccagc gccgcagcaa tacgcgccgc tgtcagttcc gcatcctcat actccttaag 1920 0 ggcactgatc cgcatcagca cccccgataa catggatgag cctcgcgtct gatgcagacg 1926 0 acgagtgaac ttcaggtgga tcatttttcc ggcagcgatt tctttcgtat cactctgccg 1932 0 gccgctgacc ggataatttt tataaaccag atattttttc ggtcttcccc actcatcaag 1938 0 aaaaaccccc tgattcagtc cggcggattc atcagtgcgc atgggaacaa aatccggctc 1944 0 catcgcctca agccagaatg gcactcccgc cgtccgttcc agaccgtttc ccgcaccact 1950 0 gaccatctgc gcaaacactt caccatcccg cagccaggtc cgcagcagta aacgttcaag 1956 0 cacaggacgg gtatactgcc ctgtcacatc cggactcacg gaccattcag cccacaaacg 1962 0 gcggatatcc gcagccagct cagccgccat ttccccgttt tttcgtaatg gctgaggctc 1968 0 cacaataatt cccctggcac caatcacccg ctcttccagc ttgtcaaaca caccaatcac 1974 0 caggtcatga ttgatatcca gaaaacgggc ctgctcccgc agggaaaccg caccgtattt 1980 0 actgagctga tcagcagagc gattttcccg ccgggcttta tgtgtccggg tcggtttcac 1986 0 cgcctcatag gccatgatta acgcccttga acgcagtctg gctgctttcc acccggggga 1992 0 aaacacgccg atcacatcat caataattgc cattaaaacc tcgccagttt aaatcccggt 1998 0 tttccccgcc tgcggctcac catcgcggca agcctgcgtt cccactcctg acgtccggcg 2004 0 cggatctgag aaaggctttc cagcgtcagt tgctgcccgt tgaagatgac agactttccc 2010 0 tccagtacgg ccatttccgc ttcacggtac cgctgtatca tttctctggc ttcttctgtg 2016 0 ctcacaacca gcctcctgat gttatccatg gattatcttc cgcacgctcc gtccgcagtt 2022 0 ttttcttccg gcgacggcgt ttttctgccc cggccgtcag ttccggggat accgtttcac 2028 0 cagaacgctc ctgcgggaag acgagccacg tttcccgctg tgcccagtcc ggtgcggagg 2034 0 gccagcggat cttttcgtaa ccatgcagaa cggcaagcgc atccgcataa accagcaggt 2040 0 caaacgcttc gttagcgccc ctgcccggtt ttcgccattt tccgtcactg ccgcgctctt 2046 0 cataggtcag ctcatcgtaa aaccaccgcc ccagccagtc gggaaagtgg atatagttcg 2052 0 gccctggtgt gtcacgccac agggcattat ttacacgatc cttaaacgca tccgtctgaa 2058 0 ccagccacag cgcgacatcg ccactggctc tggcacggcg ggcacttctg ccggtattat 2064 0 ccgggaaggt tcggttaatc agcctgtcac ggcgaagtcc atcccccttg aacagaaaca 2070 0 ccctgttgcc cagtccgtca ctccggcaac gacgccagaa acgataggcg ttatctgtca 2076 0 ccccggcttc ccctcccgta tccaccgcca tggccatcag acgcatgcgc acatccggat 2082 0 cagaagccag cggccatgtt ttatggaaca catccgtcag caacaaatcc cagtcctccg 2088 0 gatatgccgc cggatcaacc ggcagacttt caccgttggg actgcagcgc agtgaatgcc 2094 0 ggatgttgta gcgatcaaca atccagcgtt ccccctgctc tccgtatccg gtgatctgca 2100 0 caacaaaacg gcgattttta ccgccctgta cgtcaaccgt tgcctcaata aaacgcacac 2106 0 catccggcac agatcgccgg ggaaacggct cggcacgctg ttcaagcagt tcacttttac 2112 0 gctgttccgt ggctgaacgg ggcagatagg gtcgtccgat atcggtgttc accaccgctt 2118 0 tcagggtctc ttcactgccg gttcgctcat actcttcttc tgccgccagc agtttaaaaa 2124 0 tcagttgttc ccaggtctga aacgccgcag ctggcccctc catccaaaat gacgcaatcc 2130 0 gggagtttcg tggcgttccg gtgatactgc cgtccgccgc cgcccgttca ccttcacgaa 2136 0 gccagatccc ctggttattc agttcgcgtt tctgctcagg ggcaatcagc ccgcgacaat 2142 0 gcggacacat cagacgggca gcctgaccgg cagccacaaa atccgggtta ttccggtatc 2148 0 cggtcatgtt atccatcacc ggctgaaaat attccccgca gtgcggacac ggccagtacc 2154 0 accggcggcg gtctccccgg ttatacagtg acaggatccc cgttgttggc ggtgcctcat 2160 0 gtgcgccacc acaacgccat ttggtatcgg tgatatcccg ccccggtgaa ctctcgacca 2166 0 gggtcatccc cgaggacata aaggtggtgg tacgctttga ggccagcgtg aaggcatccc 2172 0 cttccccgtc cacattttca gggaaacggt cataatccgt cagcgccaca cgacggtaat 2178 0 ccgaagagga aaagacggtg atcgacggcc agccaatctt caggaaggag ccgtcaagaa 2184 0 acattttatc gtggacgttg ttgtcattac gggaaggact gaggcgcttg ctgacctccg 2190 0 gactgtggcg aaacgtcctg gaaagacgcg ttctggaatg ctcacgcgcc ttcgtctcag 2196 0 tcatctgcac caccagcata tccgccggat cacagatgat gccgtacaca atccagccat 2202 0 caatcagccc ttcggttttc ccggttcgcg caggtcccac aaacaccacc gcgtcatatt 2208 0 cacgggctga taatgtatta atggggtcaa tcatataggg cgtcagcgat gactcccacg 2214 0 gaccggaagt attggctccc cgtggaaccc gcatataacg cctgatggct tccgctactg 2220 0 gtaaccggct gggtgggcga aacagcgagg ccacttcgcg ccagatatcg gatgcgcggc 2226 0 tatggctctc gttcacctga ttcacatatc ggcctcatca caacagtcaa tgactgcctt 2232 0 ttccagtgtg tcgcggatct catcaaccac aatctgtact tcattcagtt gtgatgcagt 2238 0 ccaccccctg tccctctcca gccggtcagg ccaggtttcc agtacctgaa ctatcgcttt 2244 0 caccacgaca gaaaaggacc gcctgacatc actgactggc acaagctgaa cagtttcatg 2250 0 ctgaaattta agacgctcgc gctcggactg ataccatgcc ttacgagcgt gaggatccat 2256 0 atcctcatct tcggaagatg gtggtttttc cagcaacgaa gttatcaaat ccgtcaggag 2262 0 atacagtttt ttcttttcat tactgcctgg tgcaagagga acatccgcca ttctggcggc 2268 0 aacagtctgc cggtgcagac ctgaaagggc tgccagttga ttaatattta acttcatatt 2274 0 tttcagctcg ccgtccattt acatccctcc acataaaccg cagaacagaa gtgactctgt 2280 0 ttttttgtaa agaaatgccg ccatataaag atgtcgaaca aaaaacaacc acaatcatca 2286 0 tctttttaat actaacagca ttaaaaacaa caagttacca tcatgatgat gatgacgata 2292 0 aaatcacaaa aatgcgcctt tttccgcgcc cgcccgcccc gtgttcaggc ccaccccacc 2298 0 aggaggaccc gcaaaatgat aatggttatc atttgcaaca aaatccagtt tcttccacca 2304 0 tcgcaccgga ctggcgacta tgaggggaca acaccgcgct ccgttaacgc ggtaaacccc 2310 0 ggtgtgtatc gtttttgatt atccccgcac actctcgcag aggagtctcc ctgtctggct 2316 0 gcggtctctg ttaatgcagg aatacggtga cgatacggcg catcagcaaa acttagttca 2322 0 ggcactgagt gcggatatag tcctgtgccc cttccagctg cttctgcatt gtcatcaacc 2328 0 gttctctgag gatgaaataa tcccgttcag cggtgtctgc cagtcggggg ccggttgcat 2334 0 tatccacgcc ggaggtgccg gtggcttcac gcacggtacc ggagcaggtg gcgttgatcc 2340 0 gcaggcgctt acgaccagcg gcaacatcag cacgcagagt ttcattttca gctctcgcat 2346 0 cggctaactc cctcgagtat tttgcatcga gcgcagcaac atcacgctgg cgcacctgca 2352 0 tgtcagtaat ggtggcattc gcctgttcca gctctctggc ttttttatcg cgctgcgctt 2358 0 tgtaggtgag cgcgttgtca cggtaatggt ttgttgccag ccacagcgca ccatagccaa 2364 0 ccgccaggac aataatcacc acacacagaa cacggttcat ctctctttca ccccaccagt 2370 0 cccgataacg tcaggactcg ccaggcggtg gaaaagaaaa tggcaaccag catgactaaa 2376 0 aatgaaatgc cgacaagtac acagaggctc ttcaccagcg ttatgagttt atctgatatc 2382 0 attagccacc ccatcaatcc gcctttgtta ttttcccttt gcctgtatca gccaggacaa 2388 0 aatcaatcag catattcgct tcatttacca gcgtacggat ttttgataca tgcgcggctt 2394 0 taacctgttt ccactcattc agcccggtag caaacacact ggcaatgttt ttatcccgtt 2400 0 tcatgtcagc acaagcctgg ttgagttctt ccatcacgct cattttacgg ggattaacga 2406 0 caaaaccctt cgtccagtac tcgtaaagaa catcgtcgca ctcttcctga taccggatga 2412 0 ccttatcgcg gatttcgggt tttactttgt tgggattaat ggtttgtagc cagccggcaa 2418 0 gttttcgaag tggcatggac accatattgc gttgtttccc atcctcagca accataacga 2424 0 tttccgttat agttgacgca aaacgctgtc ttaacttagc caactgtgat tgccaggcca 2430 0 gccccatccc cgcaacgaca ggtttcatgg gaacgtatgg ttcgccatta tggttaacta 2436 0 cataaagaga gttgccgtga aacggcacgg ccatcatatt catcggttat ttccttttag 2442 0 tgatgaacct tgtctcacag gaatccagcc cacagaaagg caccgacagc caaaccggta 2448 0 tcctcaaggg tcatcctgaa aggttctgtg ttgtgagatg cgcgtgagat gcgcagaaat 2454 0 gacaaaggca tcattacggt gcctgagtgt taaacaactg ttttgacttt attcacttac 2460 0 attttgccaa tttgcaggat ttcgtgttat ccgtccatgt aagcaaacct catttttcag 2466 0 caaaatattc ttcttatctg tcgattcccc agcacgccag cgcgctctcc tggtcacgac 2472 0 gggatacctg accgtaacag ttgtttgaac gaatacggca gtctctgcca ccgtccttaa 2478 0 tccaccagcg aatagcttcg caggcacctt ttcgatcacc tgcattaatt cgtctgtaaa 2484 0 acgtcgacgg gaaacactta ccgggaccaa tgttgtacgg acagaatgac gcgatccccg 2490 0 ctttctgggg ttcggtcagc ggcactttga tgtttttctc cacccatgcc agcgccttat 2496 0 cacgctcaat ggcgttaacc cggtcgcatt tttccttcga cagcttcatg ccaggaataa 2502 0 caggcttacc atccacccgg gtggctccac ggcagatggt ccagataccc gcaccatcac 2508 0 ggtatgctgt ggtgtggtta ccttcctttt catccagaaa ctggtcgagg atttcaggcg 2514 0 cagaagcacc tgcggcaatc agcgccagaa cggcagccga taaaccatag cggagtttcc 2520 0 tgctcatcag cttactctcc ccgtgccgcc ttacgccggt cttctttaat cttgaaatac 2526 0 aggttcgtca gatatgtcag cagcccaaac agcagactcc ccagcacgcc tattgccgcc 2532 0 cactgagacg gggaaaccct gtccagcaac tgcaggaacc agtagcccgt tcccaccgct 2538 0 gacgtggtgt atgacacacc tgttgtgatt ttttccatct ggtacatacc ccgtctcccg 2544 0 caatccggaa gctcacaaca ataaaaaaga ccaccggcac acaccgatgg tccctgacgc 2550 0 atgcttacat catcatgtcg ctgtccggtg tggggtcacc gctatctgaa gcactcccct 2556 0 cacccgcgat gccttccggc tccggagctg ccggtgcgcc cagcagctca tccagaatgg 2562 0 catcaacctc tgcatcaaga cgcgcttcca ggttatggcg aagtttctgt ttcagtgcgc 2568 0 tccggacttc ttcagagcgc aggacttcct tcactgcttc agcagtgacc agggatgtaa 2574 0 tttctgacat gggattttct cgtcgaaaga tgtgattaag aaagttgccg ctaaatgagc 2580 0 ggctcttcgg gtttgcttcc ggctgactga ctggcgctga ttttctcagc ggcccttttg 2586 0 tcaatctgtc tgcgccagaa gtcacgcatg gccctgtacc cacccgaaag gagatacagc 2592 0 acacagacca ccgtacagaa gtacagcatt aactggttca gaaatgtcat aatttctttc 2598 0 cgttattgtt gacaataaga actgttttca tttaaaaaac cagagcacga aagtatcgtt 2604 0 cctttatttt ttctccatag gtattaccac cgccagcgtc cattcctgtc gctggcggtt 2610 0 ttttttatca tgccgcagtg tctgtgttgt tcacttccac cgcaatgctg tcaatcagca 2616 0 ccgggtaagt cgcacctttg gtaatgtctg tcacatgcag tttatccgcc gcaaatgcac 2622 0 tgaccggtga ctgcgtcagc gtgaacggtg tgccatcctg accatcaata accggcgtca 2628 0 cctgaaggct gttattcccg gcaaagcgga aggccagcgt atgccattcg ttatcaaatg 2634 0 cgccaaaggt tcccagtttc aggttgtttg tcgccacttt cgcattgtgg tacatcacat 2640 0 tcaggtcttt tgcatctgtc tggatgtaga acgctgccag caggttattc cccccgtctc 2646 0 cggtcagggc aacgccctgt ggcagtgaag ataccggcca gtaaaacgcc ataacatact 2652 0 ggttcgcagc cagcactccc gaaaccttaa agcggcagcg aatctgcccc cctttctgta 2658 0 acagagccgc accgttgccc gcggcgtact ccagcaccca gctgctttta ccggcttcct 2664 0 tggtcagctt cactgcctta cctccggttc cctccgcatc gctgaccact tctgccctgc 2670 0 cgccactggc tgaccatccc tgtactttca ggcttccctc tgactcgctg gcaaggtaag 2676 0 agagcagtgt tgtgacgcct gtggcttctg caccggaagg cgatgacggg cgcacctctg 2682 0 atactgtcga tgatgccccc gcgtttagcg ccactcttcc cgcatggcgc aaaatcgccg 2688 0 ttgccagacg gtcggaaata atcccacggc gtgcccaggc gctgaaatgg ctcgccctgt 2694 0 cctgtgacgt ccaggtggct gagctgtcac gccatttcga accgtaatat ccgatacccg 2700 0 gaatgtccgg gtcttcttcc ggtttgttcg tcggcacatt caccccattc tcatccgtca 2706 0 tgaacggtac gaaatggata ttcttttccg ttttgttttt gtagctgccg tacaccgtct 2712 0 ggtacgagga ttcgttcttc tgcttccaga aatacgtcgt gtccccgcat atccagggaa 2718 0 caccgtcagc agagccaccg acgcactgac ctgccatatc cgccaggtct gcacggaatt 2724 0 tatcaaccag cgcaccaaac tgtgctgcgt gatttgccgg cgtaccgcca aaatcaaatt 2730 0 ccccctgcat ccacaccacg gcaaacagca catttttcgg attcttcttc agtgctgctt 2736 0 ttgttcgacc gataaggtcc ttatacagcg gcttgtccac accccagcgg gttgaattct 2742 0 ccgaggcacc actcgcgtca ctgtatgtgc catcggctcc ggtggtgaac gctgaaccac 2748 0 cacgacagca cggaaccagc agaatgcccg cattcgccgg tataaacggc agcaattttt 2754 0 tggcgatatg cagcccctgc cccacggttc cgtactgccc ctttgacagg tccgctttcg 2760 0 gatggttaag gcggctcatg tcctgcacat catgcagaca atggtccgcc ggaatgatgt 2766 0 cgttatattt acaggcgaca ccgcccggtg tcaccgtact gcgacgcgcc agctgcttaa 2772 0 tgcgcgggtc cggacggtca tatgtctccg gcagcggaag accttcacca tacgacatgc 2778 0 cgtttgactg ccctgccaga accacaacaa agtaataccc ggggtcgctg gtggcgctga 2784 0 ttactgcacc ttctccacct gtcagcttca ccacaacagg tgtgctcaca tcaccttctg 2790 0 cgacaatcgc ctgaataagt gctgcgccat catccgtata cgaagaaaac ggcccaccgt 2796 0 atggttgcca tccttcacga attttttgcg caagtgcatc agcaaggtct gacggcgatg 2802 0 ccgccctgac cacatcgtag tgtttaaatg ccatgaatcc tcccggccgg gataatattg 2808 0 tgagtaaaat gatgagcggg ctgaaatccg gaagttacag gacaatggca gaagagagac 2814 0 aacagcccgc aatacgaaaa aggccgcgct attgcgcaga gtgattactg tcggatatta 2820 0 ttcgccagct gaaatattac ttcacgtttt gttgtttatt ccttgccgcc agcgtctccc 2826 0 tgcgcgggct ttttttgtcc ataagaaagc ccctccggag aggggctgga gagtggcgct 2832 0 atgtgccatt gcatggtgcc gggtgcctcc cggtgagttc ggcctggtgc caccaaaccc 2838 0 gcgtattctc gcttacgatc atcaaagaga tcataccgtt caccagtcgc ccctccgcac 2844 0 agggggattc accatgcaga aattttctaa cacatctatt atcagaccgg caacaactga 2850 0 ctgaattgag atgtatttaa catttatgaa tctccgcctg ctattttcac tgagctattc 2856 0 taagtcaacg aaaaataact tcgctgaatc cccctccatt atgacaggca ttagttttaa 2862 0 tggttacagt catccccgta atttgcgcac tgagaagaag agactgaaga ttccatctgt 2868 0 tggtaaataa ttctttatca cccactttaa ctgtaaaggt atcgtcatca ttatattttg 2874 0 tatactccac ctttccagtt acacaatcag gcgtcgccag cgcacttgct gaaaaaaatg 2880 0 aaagcgatgc agctattaat aatgtttttt tcattttacc ccctcaactg ctaatagttc 2886 0 tgcgcatcag aattgccccc agagtggatg aatcccacaa tattttattg tgcgtaatcc 2892 0 cacggactct tccatctgcc ggacacatag aaggaaactc atcagatgcc attctggcaa 2898 0 ctcgcgatgc atgatgatga caattcagta ttaatgccac gcttcccaga attgcattaa 2904 0 tgcttccaaa agaaattctt cctacacgaa cagagtcttg tccatgataa tcaggcagga 2910 0 cactactcaa ccttccccag ttcaatgtaa gatcaacatc ttcagcagtc attacataag 2916 0 aacgcccact gagatcatcc agtgttgtac gaaatcccct ctgtatttgc cgaaaacgta 2922 0 aagcttcagc tgtcacagta acaaaccgta acatcgctct tgccacagac tgcgtcagtg 2928 0 aggttccact atgcgacatt aaatccagat aagaagtagt caacgaatgg cgatttatct 2934 0 gcatccccgt acgactgatc cctgcaacac gctgtaacgt ggtatagcta ctgtcaccag 2940 0 acaatgtaac cgctgttgta cctggaaagg taacatgtga aaaatcagca aagcgataaa 2946 0 aaacattatt tgtcctgtta acaaatcctg tcacatataa attatttcgt tcaacaataa 2952 0 gccgtagatt attaaaccgc ccttcctctg gatctatccc tctgacatca actgcaaaca 2958 0 aattatcccc tgtgccacta tcaatcatca gtaaagacgt acctcctgat gaaatagtct 2964 0 gtaatggagt acctattgca gagcgaatga cattcagcga atctacatac gtctttgcag 2970 0 tcgagaagtc taaggtaaat tccttcgcaa ccacattaac tgaaaagata acaaagaaaa 2976 0 aagttagcac tctaaaaata attattttca tattacacaa tactccttga gcaccatacg 2982 0 ataactatat tcttgacatc ctccaccccc tgaaggacgg cgttttacgg cgcaccggat 2988 0 aaacgtaaca ataacgtaat gaaaatgata attatattca aagagagctg caaccttaac 2994 0 atatctggtc agatctcatg cgactacttg acgtacgtag acaacaacat ttattgatac 3000 0 acaggatgtt acggacataa aaaagccagc cactggggga ggctggcaaa ctcgtagagc 3006 0 aaaatgctgt tacgcaaact tcgttacagg gtcatcctgc aatacaaaaa atacacaata 3012 0 tttagaaaac taatagtgcc atgtgcaatt tttaagattt tgttattaat tgtggtcgca 3018 0 ccttcctttc tgtgtacttt ccgtatagct cacaggattc tgggtacaaa aaaacccgcg 3024 0 catcggcggg ttaagcagcg tggcaatgta accactctta tcatgatatg cagattttta 3030 0 cgatcgtaaa ctattttttc gctgataaaa tacagaggtt ctccctcccg gcaattcacg 3036 0 ctcaacatac cgatccatct caagcctcac tcccagcatc atcagcatgc cttcaacaat 3042 0 cccctccgct ttgtgaaggc gtttacctat acaggtgtca gagcacccat gtttccgtgc 3048 0 cagcgccatg aacgtccccc ccagcacgta ataatcaacc agcaagtcat gcagatcgcg 3054 0 attgttccgg taaaggcggg ctatacaccc gcatatcacc atcgcatcat cgtcacagca 3060 0 ctgcgggcgt gattttactt tttcggggat cagtccctta aatccggcgg caatgggtga 3066 0 ccaggtcaca tcctcatggt tatttgccgc ccatgccccc cagcactcaa gaacctgccg 3072 0 gatatcacgc atcagtatct ttaccccatc cgcgatgaac cataagaaca ccgttgacaa 3078 0 tagcgtgtct ttttccttct ttatcgccag tgtattttct gaccgtgttg cgactacagt 3084 0 tcagtattct ggctacctcg gtctgatttt catatgcctc aacgagcatg tcaggaatgg 3090 0 tttttactgt gaacgtcatg cggcctcact tctgctgttt cgcaggtctt taagtttctg 3096 0 ctgatacttc gccttgatgg ccctgcactc ttcgatagtc cagcgatggc ggttatggtt 3102 0 tgattcgatt tcgtctactg cttcctgccc gattcggtta atcagttcga cgcgataggg 3108 0 aacgagattt ccgcttttat gctggttgca caccacgcat tgcttgtgaa tattgcgttc 3114 0 atcaaatcgg agttgaggtg ccgcagcagt tgtccggtaa tgtccggcat cccactgagc 3120 0 agacatgagc gttccgcacg agatacatgg taagtcgcgg tctctttctc tgatgaaggc 3126 0 gtttacggct tgttgggctt gtttaatcca gtaactgcgg ggctttaagg cgagttttcg 3132 0 aatcttcagt ttatctttct gtttctgctc ctctcgtcgt cgtttcttct ctgctgcttt 3138 0 ttccgctttt tttcgctgtt tactttgtag tttgagtgct aactgagttc cgtgttccgg 3144 0 gcagcaccac cactgatttg agaatgccgg gtgaaaccat tccttgcata ttttgcattt 3150 0 ccttcgcgct ggtttagcca tcgtcttctt cctcgtacat tgagctattc ggatcgctca 3156 0 tcagttctgc acagcagtgc tcacacacgt gaacttccag cacatgcagc ttctgaccgc 3162 0 agttagcgca cgttaaagcc cgctcgacgc tttctttctg gtattgaagg gattgggatg 3168 0 ggctaagcat ggctttcacc attaaaaagt cgcttgtaag catcaatgtc tcgttttgct 3174 0 tcaccgagct ttcgtcttaa ttccatgttt tctgattcaa gcttttccat gtcttgttgg 3180 0 tatcgatcgc ggtgttcttt ccatgctttt tgatacgcct tcatgtatgt catattggcc 3186 0 tttctctttg cctgacgaac tgcgtggtgg tttttcacaa accagtcagg gtcgttaaat 3192 0 gctgctctgg cgcatgtata ccaataattt gttgcctccc tgtttagcca ataaatactg 3198 0 ataaatggca accggataga caccattttt cgttgtgact ctttctcgcc aaacatgtgg 3204 0 ccttttttga tgctaagtcc aaatccaggt tgaattaaaa gcattgtcat ttcctcgcac 3210 0 gatgtcttag ccaccggata tcccacaggt gagccgtgta attgaaggtt tttacgtcag 3216 0 attcttttgg gattggcttg cgtttatttc tggagcgttt cgttggaagg tatttgcagt 3222 0 tttcgcagat gatgtcggtg atacttcgtc gctgtcgcct catgcagccc tcctgacgcc 3228 0 cagcccgatc gccatcaatg ccgctttgga tacggtagta aacatccgtc gaggactgat 3234 0 gaacggtcgc caaatcagca acattgagcc tttgctgttt cccttcttct ccagccctgt 3240 0 cgatggttcg ataaaattaa tccgtccatc agtgatgatg cgaacttcgt caacactctc 3246 0 cagagccttg ctgaaccatc cgacagacat atcctctggc acaagcatca ctaccgtctg 3252 0 tcgctgttgt atgcactgct cagcggcttt ttccacccac ggcctgatat tgctgtacgg 3258 0 tgggttattc cagattgcac cgtggcttat ccactcagaa tttagcgcgt cgtcagcctc 3264 0 agttagccag tgagcacaca gagcgttttt gtcgctcgca gctgaatcca gccagaatcc 3270 0 aaactcaata tccagtgcat caaaaagcca aagcggcgtt tgccagcagt ccttgtcgtg 3276 0 tgctggcgta tttgatttga tagtcatgca gccctacctt ttcgttgtga ccattcatac 3282 0 tctcgccggg agtcatcact ccaccgcacg ttgcgctctg agccgaacca gaacatgatt 3288 0 tcgataagct cagtcatgct ggccttccgc attttgctgg tacgcacgcc aagcatgaca 3294 0 acgccaccgt cgataccagg cacacttcgt tgctccagtt ttttggtctt aagccacagg 3300 0 gcagtgaaca ggtctttcca gtcttccggc gccagccgtt gaccatgcca tagcacctga 3306 0 cgcgaaacat cgttcagcat cggccacata cggtcattct gcgctttgct gcgcctgggt 3312 0 tctttaacgt ggacttcgtg gggtgacttg tcgtcgatgg gtagtgagag aatggcgtct 3318 0 atggcgttat ttctgattgc ttcgttgcga agcagaaagg tttgcttcat ctcctgctct 3324 0 ccggttccat ttttcagccg ccgcagcaac tgatggtgcc catgcccccc tggcttcaca 3330 0 gaggtcacat tctgcatagc cccacacatc aatatttatt ccggcctcaa cccacagacg 3336 0 agcattaccg ccgcaaaacg gacattcttt tagctttggc tgggttaatg ataggtcgct 3342 0 catgctcact ccttcactta aaatccagac tccggataat tctgttgcgc tgaaactcat 3348 0 tgttgagttt gaacaaccgt cgaagaacac ggtcacgcgg atagcgtcgt gcggcaggtg 3354 0 aatgctcata caactcatca agcggcaaac tggacgatga acgataccga taccaacgca 3360 0 ccaactcttc acgaaaatta gccctgacaa gctcagctat cgtactcatt tcttaaaacc 3366 0 tcctcaaacg cattctgacg catttttcat tctcgctgct tatcggcata ccttgcacgt 3372 0 gcttacctca ccacagagcg attgtgatgc cttaaaagcg atttattgaa gtgatatttg 3378 0 cttaatcgaa attcttttct ttgattcctg cggccctgat ggctttcatt actgcaatta 3384 0 ccgttttgtc acgcccatcc tcataaccca tcgcataagc accttcttca ccatctttcc 3390 0 aaaggtcgtc attcgattcg ggccagtcga tatccagttc aatagcagag cgcgatgcct 3396 0 gccatatcac ccaggcaaac tcttttaatt catcgtctcc cgtgaactgg cttttgtctt 3402 0 ttgaccacca gttttcaaac tgtcggtagc tatcgttcac ttccctctcc cccaaataaa 3408 0 aaggcctgcg attaccagca ggcctgttat tagctcagtg atgtagatgg tcatctttta 3414 0 actccatata ccgccaatac ccgtttcatc gctgcactct ggcgacactc cttaaaaatc 3420 0 aggttcgtgc tcacctttcc ttcccgttct tccctggtag caaaccggta atacaccgtt 3426 0 cgccagacct taccttcgat aaccagaaga cctgcccgtg ccattttagc tgcggcctga 3432 0 tttatgctgg ttactgttgc gcctgttagc gcggcaacgt ccggcgcaca gaagctatta 3438 0 tgcgtcccca ggtaatgaat aattgcctct ttgcccgtca tacacttgct cctttcagtc 3444 0 cgaacttagc tttaatttct gcgatcttcg ccagcgcctg aacacgattt agaggtctgc 3450 0 cgcccatgac aggaagttgt tttactggtt caggtatcgc ctcaccacgg ttaattcgcg 3456 0 ctgtcataca ggtcagttca tcggcagcct tgcgtcgtaa ttccgcgtca gtcagcgcat 3462 0 tggcccgcat gttctggtac aggttggtaa ccagccagta gtgcgcgttc gatttccacg 3468 0 gataagactc tgcatccgga tacaggcctc gcttccggca atactcgtaa accatatcaa 3474 0 ccagctcgct gacgtttggc agtccggcga taacggatgc ttcttcccgg caccatgcaa 3480 0 caaactgccc gggtgatgga agaaatggtc gattctgccg acgggctacg cgcattcctg 3486 0 cgttaacctg ttccatcgag gtgatcccgt tttcccggaa agccagaacc cactggcggc 3492 0 ggatttcgtt cacttcgttc tggtcacggt tagccaggct cgccgggaaa gttgccagta 3498 0 actggctgaa cacaccgttg atgatctgcg ctacctgctg tacctgcggc ttttcgtcgt 3504 0 actgttccgg catgttgttg gcgatccgac gcatctgctc acggtcaaag ttaaccatct 3510 0 gtgcggcgat gtttttcata gatccacccc gtaaatccag tctgtgtttg tcaggtcgag 3516 0 ttttggtttg ctggctgtca cgcctgcctg ttgcttgtta cggttgattt cgagttgggt 3522 0 ccacttatcg cggagtttgg ccgggctcag cacgttaccg gaccagaagt tgtcctggca 3528 0 tgcccagcgg aacagcacgc acatgtcgcg gtggttacgt ccgtcacgtt cacgcatcag 3534 0 gcggatatcg ttagcccacc ctgcaaaatt cggttttctg gctgatggcg cgatggtctt 3540 0 caccatgtca aacatccact ctgcggcggt caggtcttct gctgtccccc acttgctgcc 3546 0 gctctgaatt gcagcatccg gtttcaccac agaaaggtcg ttttctggct ggtcagagga 3552 0 ttcgccagaa ttctcggacg aataatcttt tcttttttct tttgtaatag tgtcttttgt 3558 0 gtccccctgt tttgagggat agcaatcccc taatttgagg gatgttttat ccctcgtttt 3564 0 aggggatttt ccctcgtttt gagggatgtc cctcatttta ggggaacctc cctcgttttg 3570 0 agggatgcac cattctgaga tgtttttatt tggtccaaac atgccgcctt gctgcttgat 3576 0 aatattcatt ctgacgagtt ctaacttggc ttcattgcac cgtttgacag gtaactttgt 3582 0 aatctcgcta agttgagaat cggtgattct gtccattggt ttattccacc cataggtttt 3588 0 acgcagaatg gcaagcagca ctttaaactg tcgcttggtc agatctgcgc ctgaataagc 3594 0 ctcaatcagc atatttgata gtctggcgta accatcatcg agatctgcca cattacgctc 3600 0 ctgttcggca aagttacctc tgccgaagtt gagtattttt gctgtatttg tcataatgaa 3606 0 tcctgtggat tgatccagta attccctcag aattgcatat caatttgctt agagtccccg 3612 0 gcggccaccg gggatttttt ctttgtgatt ccatccaatg catacttaaa agccctgcta 3618 0 atcggactga tgtctgatgc cattccgaaa gcacacaaga ccgaagcaat aaaccgccag 3624 0 tccgttctgc ttatcttcga ttcatgacag ccaatcatct ttgccagacc gcgctgggta 3630 0 agcgttgaca ggttgatgag taaatcagtt tcagcgcgat caatttctcg ctgtgttggc 3636 0 ttgctgtagc ttgcttgtgc catttgttaa ttttcctata ttgatattga gttatagcgg 3642 0 cacacccaat ggatttgccg ctgatgtttg ctcacccggt tagaggtgaa aggccatgat 3648 0 gaaagagcgg gtactgctta ggcggctttg ttactggatg gagggaaaac atcatccaaa 3654 0 gaacattggc accctaactt cctgaggcct tctacgatca ttcggcaatc gttaaggcca 3660 0 ggagtacgga tattcagctc atagttggcg atgcgggatt gcccccaacc aattgccgaa 3666 0 gctagtacag cttgcgaaac tccgattttt tttcgctgct gggcaatttt gttcattgcg 3672 0 gtctccctag cattaatcac acacccatta cacacaattt gtgattaaca gtcaacctca 3678 0 attcgtgtac agagttcaat cacgttgcgt gttacattta agggatgaaa acgatgcatg 3684 0 aaattatcgg ggaaaggatc aagtccctta gagaagctaa aggacttagc caggctcaat 3690 0 tggccaagct ttgcggctgg gctgcgcctt cacgcctggg gaactacgag ttaggaacaa 3696 0 gaaaggttag cgcggatgac gcgctggttc ttggggcggc actcggcgta tctccggcaa 3702 0 aaataatgtt tggcgaggat tcagacgccg tatttcgcca atatgaatac ccgttatttt 3708 0 cttcagtgca ggccgggcca ttttcggagg tgggaagcta cacagccagc gatgcaaagg 3714 0 catgggtccc aacgaccaca aaagccagcg aaaaagcttt ctggcttgag gtgaaggggc 3720 0 attcaatgac ggcgcctcag ggggttcgtc caagttttcc ggaaggcatg ctgatactcg 3726 0 ttgatccggc tgagccggta gagtctgggg atttctgcgt ggcttctgca aatggtgatt 3732 0 cagaggcaac gttcaagaag tatgagaagg atgcaggggt tagttacctg gtacctttaa 3738 0 acccggcata tagaaccctg gattgcgacc atagctgccg catcataggc aaggtagtta 3744 0 aggcgcagtg gcctgaagag acgtttggct gatcggcaag gtgttctggt cggcgcatag 3750 0 ctggtaatcc aacttttccc tgttcttttt atgcaaatta atctaatgaa attgaaaaga 3756 0 tttttaccta ttttgttggt tcaggagaac ataaatgagc gataaacaag aagtttcctt 3762 0 agcacatatc aatgatgtgc tggagtccaa aaattatatt gaaactaatg ctgatggggt 3768 0 tgtaaccatc ggaacggata acaatggcta cgaagttttt aacttcgttt ttctcaatag 3774 0 cacccctgtc atcggccata tgaatggcga aatcgcagtg gcaggaatgc agcgcactaa 3780 0 ggttgcgtcc gtgactttaa gtaaacagaa ggccttcgat ttctatcagt ccttgaaaag 3786 0 catgttcgag gaataaaagc tgatgaatgc agctcaatca tctttggatg agggaaagct 3792 0 agtaattgct tactctgata agaatggctc tacagtaggg ctggaatttt cttctgtagc 3798 0 atcaagccaa gcaacgctct tgatgaaagc ttgttctgtt gctgcttcag ataaagaaaa 3804 0 acggattgtc acatcggttg tgatggatga tactgagatc attcaaacaa caagtgatga 3810 0 tggaggcgac gacatggata agcgattagc agttcttgaa gctgaagttg cgcacatcaa 3816 0 gagcagcatg gcaggaatta aagaggatac ccggaaaata tcttctgatt ctactgacgc 3822 0 caaaagagac accgctgtac ttttacagaa gagcctggat tttgatgctt cattatctaa 3828 0 gaaaccatcg gttgactact ttgaagctaa attttccgct ttggaaacca agatagcaga 3834 0 tgtaaaagta tggatgctcg gggttctctt ggcctcgctt gctatgccaa ctatattttt 3840 0 cctaataaac ttgtacctta agaaaggtca gtaatttagc aaatccggcc accgagccgg 3846 0 gttttttatt gcccgccgat cactatcagg acagcacctg cccgccggtc caaactattg 3852 0 attaaattac tataattctt aatacaactc ccatatcccg ccatctcgcc accaccccat 3858 0 tcgctcgttt ttcgaacttt tcagcaccca tcctgctgtt gccaccgact taagtaagca 3864 0 aaaccatcgc gggtaaaact atttacacaa aaaaatcata cacataacgt gtcacacctt 3870 0 tattttacac attttgtgat tgaccattaa atcacaatat gtgactatca tttccatcag 3876 0 caggacgctg agacgccaca aggaacagat tggcaggctc tttaacatcg acgaactctc 3882 0 aacctaaccg ttgagaccag aacttgagtg gttttgggga tggcgcgaat tgcagctgca 3888 0 agacagcgat cgagaagata aacacctcga cgcgtcatgc gccaaagcca cttaaaggag 3894 0 accatcatgg taaccattgt ctggaaagaa tccaaaggta cggcaaaaag ccgctacaaa 3900 0 gctcgcagag cagaacttat tgccgagcga cgcagtaatg aagcactggc gcgaaaaatt 3906 0 gcgctaaagc tctctggttg cgtcagagca gacaaagcag catcactcgg aagccttcgc 3912 0 tgcaagaagg cagatgaatg cagtggaagt atttgcctgc caaacgtagc catttacgcg 3918 0 gcaggctacc ggaaatcaaa acaactgacg gcgagatgat aaattaattt gctaattact 3924 0 tgtttttgcc atgcttatcc tgagcgataa gttcatccat aagactgtct ttcttcccag 3930 0 caaacctaat gtagcactca tttctatagc gttccgggat aacaaaacgg tcgatttcag 3936 0 gatatccagt agcagaaggt acccgaataa gaagcccttt ttcgagcaat gagattgctt 3942 0 cagggcttcc cttttctgtc tttagctggt tattagcggc tacagcgaat gccaaatacg 3948 0 ctctttctcc aagagttaac gaatcaaaca aatcttgcac gtatttctct tctttagatt 3954 0 tgcgcttctg agcagcgaat atctcaattc tttcagtcac agcgtgataa gcggaattaa 3960 0 caacgccgtt aagcacatag ctaacgcaaa acaacaggat gtaatacatc cagtaatgag 3966 0 gaaggatttc tggattatgc aggtttatcc attcttttac gcttacaggc ataacaataa 3972 0 tcaatataat caggatgatt agcatatgaa tcaactgttt aagtgtcatt ccttgcagga 3978 0 aaaaatgcat tagttcctgc caccatgagt tgttcatcgg cgtttctctt ttgctctctg 3984 0 taggggtgaa tagagtttat ccgatttctc gctgtagggg tacacgagaa ccaccgagcc 3990 0 tgatgtggtt aaaagacagg catactaata aacactgcac tgtgtattca ttccaacgag 3996 0 tgaatacact gagcaatgtc gctcgtaact aaacaggagc cgacttgttc tgattattgg 4002 0 aaatcttctt tgccctccaa tgtgagggcg attttttatc tgtgaggata tgaacagatg 4008 0 tcaaacatca aaaaatacat cattgattac gactggaaag catcaataga aattgaaatc 4014 0 gaccatgacg taatgacaga ggaaaaactt caccagatta ataatttctg gtcagactct 4020 0 gaataccgac tcaataaaca cggctctgta ttaaatgctg tattaatcat gctggcgcaa 4026 0 catgctctgc ttatagcaat ttcaagcgac ttaaatgcat atggtgttgt gtgtgagttc 4032 0 gactggaatg atggaaatgg tcaggaagga tggccttcaa tggatggtag cgaaggaata 4038 0 agaattaccg atatcgatac atcaggaata tttgattcag atgatatgac tatcaaggcc 4044 0 gcctgagtgc ggctttaccg cataccaata acgcttcact cgaggcgttt ttcgttatgt 4050 0 ataaataagg agcacaccat gcaatatgcc attgcagggt ggcctgttgc tggctgccct 4056 0 tccgaatctt tacttgaacg aatcacccgt aaattacgtg acggatggaa acgccttatc 4062 0 gacatactta atcagccagg agtcccaaag aatggatcaa acacttatgg ctatccagac 4068 0 taaattcact atcgccactt ttattggcga tgaaaagatg tttcgtgaag ctgtcgacgc 4074 0 ttataaaaaa tggatattaa tgctgaaacg gagatcaagc aaaagcattc actaacccca 4080 0 tttcctgttt tcctaatcag cctggcattt cgcgggcgat attttcacag ccattttcag 4086 0 gagttcagcc atgaacgctt attacattca ggattgtctt gaggctcaga gctgggcgcg 4092 0 ttactaccag cagatcgccc gtgaagagaa agaggcagaa ctggcagacg acatggaaaa 4098 0 aggcctgccc cagcacctgt ttgaatcgct atgcatcgat catttgcaac gccacggggc 4104 0 cagcaaaaaa gccattaccc gtgcgtttga tgacgatgtt gagtttcagg agcgcatggc 4110 0 agaacacatc cggtacatgg ttgaaaccat tgctcaccac caggttgata ttgattcaga 4116 0 ggtataaaac ggatgagtac agcactcgca acgctggcag ggaagctggc tgaacgtgtc 4122 0 ggcatggatt ctgtcgaccc acaggaactg atcaccactc ttcgccagac ggcatttaaa 4128 0 ggtgatgcca gcgatgcgca gttcatcgca ttgttgatcg tcgccaacca gtacggcctt 4134 0 aatccgtgga cgaaagaaat ttacgccttc cctgataagc agaacggcat cgttccggtg 4140 0 gtgggcgttg atggctggtc ccgcatcatc aacgaaaacc agcagtttga tggcatggac 4146 0 tttgagcagg acaatgaatc ctgcacatgc cggatttacc gcaaggaccg taatcatccg 4152 0 atctgcgtta ccgagtggat ggatgaatgc cgccgcgaac cattcaaaac ccgcgaaggc 4158 0 agagaaatca cggggccgtg gcagtcgcat cccaaacgga tgttacgtca taaagccatg 4164 0 attcagtgtg cccgtctcgc cttcggattt gctggtatct atgacaagga tgaagccgag 4170 0 cgcattgtcg aaaataccgc atacactgca gaacgtcagc cggaacgcga catcactccg 4176 0 gttaacgatg aaaccatgca ggaaattaac actctgctga tcgccctgga taaaacatgg 4182 0 gatgacgact tattgccgct ctgttcccag atatttcgcc gcgacattcg tgcatcgtca 4188 0 gaactgacac aggccgaagc agtaaaagct cttggattcc tgaaacaaaa agccactgaa 4194 0 cagaaggtgg cagcatgaca ccggacatta tcctgcagcg tactgggatc gacgtgagag 4200 0 ctgtcgaaca gggagatgat gcgtggcaca aattacggct cggcgtcatc acagcttcag 4206 0 aaattcacaa cgtaatagca aaaccccgat caggaaagaa gtggcctgac atgaaaatgt 4212 0 cctacttcca caccctgctg gctgaggttt gcaccggtgt ggctccggaa gttaacgcta 4218 0 aggctctggc ctggggaaaa cagtacgaga acgacgccag aaccctcttt gagttcactt 4224 0 ccggcgtgaa tgttactgaa tccccgatca tctatcgcga cgaaagtatg cgcaccgcct 4230 0 gctctcccga tggtttatgc agtgacggca acggccttga gctgaaatgc ccgtttacct 4236 0 cccgggattt catgaagttc cggctcggtg gtttcgaggc cataaaatcg gcttacatgg 4242 0 cccaggtgca gtacagcatg tgggtgacac gaaaagatgc ctggtacttt gccaactatg 4248 0 acccgcgcat gaagcgtgaa ggcctgcatt atgtcgtgat tgagcggaat gaaaagtaca 4254 0 tggcaagttt tgacgagatg gtgccggagt tcatcgaaaa aatggacgag gcactggctg 4260 0 aaattggttt tgtatatggg gagcaatggt aatgaagcat cctcacgata atatccgggt 4266 0 aggcacgatc actttcgtct actccgttac aaagcgaggc tgggtatttc ccggcctttc 4272 0 tgttatccga aatccactga aagcacagcg gctggctgaa gagataaata ataaacgagg 4278 0 ggctgtatgc acaaagcatc tcctgttgaa ttaagaacga gtatcgggat ggcacatagc 4284 0 ctcgctcaaa ttggagtcag gtttgtgcca ataccagtag aaacagacga agaatttcat 4290 0 acgttagcca catccctttc acaaaagctg gaaatgatgg cggcgaaagc agaagcaaac 4296 0 gagagagacc cggcatgaca acaacagaat gcatttttct ggcagcaggc ttcatattct 4302 0 gtgtgcttat gcttgccgac atgggacttg ttcaatgaca cctcagcagg aaaacgccct 4308 0 tcgcagcatt gcccgtcagg ctaattctga aatcaaaaaa gccagacagc agtttccgga 4314 0 taaaaacgtc gatgacattt gccgtagcgt actgaagaag caccgcgaaa cggtaacgct 4320 0 aatgggattc acaccgactc atttaagtct ggcgatcggc atgttaaacg gcgtctttaa 4326 0 ggagcgatga acatgaaaag caaaatcatc agggagctac aggctccttt tttattgttc 4332 0 gcattcaccc tcaagcgtat taaccaacaa ttcagggatt aatggaagat ggcagacatc 4338 0 attgattcag catcagaaat tgaagaatta cagcgcaata cagcaataaa aatgcgtcgc 4344 0 ctgaactacc agactgtatc cgcaactcat tgttgtgagt gtggcgatcc gatagatgaa 4350 0 cgaagacgcc tggcagttca gggttgtcgg acttgtgcaa gttgccagga ggatctggag 4356 0 cttatcagta aacagagagg ttcgaagtga gcgaaattaa ttatcaggca ctgcgtgaaa 4362 0 aggcagagaa agcaactaaa ggaagctaca tcgtagggca tacatctgtt aaccagcacg 4368 0 gcaatttaac aggagttttt gtttgccaaa aatggaaagg agaacccggt ggtgtgattg 4374 0 cggaatgtca tgttaactgc ctggttgaaa cagatgttca ggcttatgca aacgctgaat 4380 0 ttattgctgc ctttaatcca aatgttgcgc tggcgcttct ggatgaacgg gaaagaaacc 4386 0 agcaatacat caaacgccgc gaccaggaga acgaggagat tgcgcttacg gttgggaagc 4392 0 tgcgtgttga gcttgaagca gcaaaatcaa aactcaacga gcagcgtgaa tattacgagg 4398 0 gagtaatcgc ggatggaagt aagcgcatag cagaactgga aaaacaatgc gccgaatggg 4404 0 agcgaaaagc attaagcaac tttgaagagt gtgctgcgat ggctgaacgt atcgaagaga 4410 0 tgcagacaaa atctgcacca gattcgtttg gcatcatcgg tgaaaatatt cgaacacagg 4416 0 acaatcgaat aacgtcagat cccatgtttt gtgtgtatca aaagcgcgaa atcgctgttg 4422 0 atgctgatta tgaccatgac cggattgtct gggttgacga agatggcaat gaagccaata 4428 0 aacgccatag tcgtcgtctc gagctacttc atgaaaactt tcgagagcca ccagaaaaat 4434 0 ggcggcgcgt tgctgtgaaa gatattgatg aattcgttac ctgctgtttc accgaacagg 4440 0 gttgtaaaga ctacctggca gtcaatggtc acaatcttcg cttgccattt atatatgtaa 4446 0 aaagcggttt caggaacgct gaatatatcg gcataagaaa ctggcttgct ggcattcgca 4452 0 tcaaaggaga gtgatatggc gttaacacac cgcgaactct gtcagattgc gtacaagttc 4458 0 cttaagcgca acggtttcaa ggtttgtttt catgaccgct ttatagctgt aaccagtacc 4464 0 ggagaacagc cagatgctat gggattcaga aattcagcat catgcctgac tggcgaaatg 4470 0 ttctcgtgct gacttgttgg cagatagaaa aaagcgtttt cgtaaaaatc cgtctcttgg 4476 0 aatgggcgac tggcgattct ttattagtga gccgggaatt atttcaattg aggatttacc 4482 0 acctggctgg ggattacttc acgttgttaa cggaagagta cggaaagtac atgggtggcc 4488 0 caagggtaat tgctgttggg gtaatcctga cgataagcca tttactggaa ataagcaggt 4494 0 tgaatgcgat tacatgttgt ctgcattaag gcgcatggag ttgagagggc accttaatga 4500 0 aatatatgac ggtgtaattg ttaataagaa agaaggaaac gcggcatgac cactattacc 4506 0 gacaaagaac tgattaaaga aatcaaagag cgcataggca gcttggacgt tcgagacaat 4512 0 attgagcgcc gtgcttatga aattgcactg gcatcgctgg aagcagaacc gatagcgtgg 4518 0 gaatgcggtg aaaacataat cctgtttaac cctgacacag ttgaagcata cgcaaaacgt 4524 0 gcggaaatat cacctaaacc actattctcc gcgccgccag cgctggtagt gcctgataag 4530 0 ttgccgcgtg aatacagaaa cggttggcct cttgcgtata gtgattatgc tgaaggctgg 4536 0 aacgactgcc gcgaagccat gcttcaggga gataaatcat gattaatcgt atcaagctgg 4542 0 agcacatcct cgaatatgcc aggcagcaga ggcatattgg tcagcattgt aaaattccac 4548 0 caggagatat ggttgaaatc atggagattg ccatgcgcaa ggctggcaac tctccggtaa 4554 0 ctccggatgg ttggataagc tgtagtgagc gaatgccgaa cgataaacag tatgtttggt 4560 0 gttgggggaa gtcttacggc tggactgagt gcgatacctt cgaagggtat tacgattgtt 4566 0 cgagaaacaa atggtgggca gttactgaca atggggaaga accggcatcg aaagtaaccc 4572 0 actggatgcc gctaccggag ccgccgcagg aggtgaaatg atgaattggc ctgaagcatt 4578 0 caccgcagtt ggagttgcaa tagcggtggc atttattctg tattcgcttt tccgctgggg 4584 0 ataaaggaat gttcgccctg attcaacgtg gtcagatata cacggacaga gccggatacc 4590 0 ctgtggtgat tactcgcagt actcagcact cagtgttctt tcgacgcatg gacgggcgct 4596 0 ccggacgggt acgcattggt gagttcaaca acctgttcga acatattgac caacaggagt 4602 0 accgcaaaat tctggcgggc actgagcagg aaatgcgcct gaaaaaatta cgcgcaatgc 4608 0 aacggaggtg atacatgcat acggcttttg agttctgggt tcgcaagaca ttcggcaatc 4614 0 gctacgacct gacccgtgat gtcgacggct tctactgccg tgaagttgtg aaacgaatgt 4620 0 ttgacgtgtg gtgccactgc cgtggatgaa agttttatga ggttggcatg cagacaatca 4626 0 tctatcagat aacccccagc aaatggtgta cggagagagt ccttattgca tcaacagggc 4632 0 taaagcccgg caccatcgag cgggccagaa gaaagtcatg gatgcaggga aaagaatacc 4638 0 gccattacgc tgtagaaggt gatcctgggc attacagtga atgcctgtac aacatcgaag 4644 0 aaattatgcg atggatcgaa aaccagaaac aaccaggtgc caaaaatgca agttccggtt 4650 0 aacctgttaa tgctcctgga cgtctgggag gtttaatgag taacgcatca tacccgacag 4656 0 gcgttgaaaa ccatggcgga tcactccgta tatggtttca ctataatggc aaacgtgtca 4662 0 gagaaaacct cggtgttcct gacacagcca aaaaccggaa gatcgctggt gaacttcgca 4668 0 cttccgtttg ttttgcaatc agaatgggga gtttcgacta cgccgcgcag ttccctaatt 4674 0 cccctaacct gaaacacttt ggtctgggaa aaagagagat aaccgttaag gcactttcgg 4680 0 aaaaatggtt ggaccttaag aaaattgaga tttgtgcgaa tgcacttaac cgttaccagt 4686 0 cagtaattaa aaacatgtta ccaatgttag gtgaaaaaaa actggtttca tccataacaa 4692 0 aagaggattt acttttcgta aggagagatt tgttgaccgg ttaccaaaag ctttctaatg 4698 0 gaaagacttc ttccataaaa gggcgctcag tggtcacggt aaactactat atgacaacca 4704 0 tagctggaat gtttcaattt gcaacagata atggttatac ctcaggaaac ccatttaacg 4710 0 gtctggctcc cttaaaaaag tccaaggtaa aaccagatcc tctcacccgt gacgaattta 4716 0 ttcgttttat tgaggcttgc cgtcatcaac aaacaaaaaa cctgtggatt ctcgctgtat 4722 0 acacgggtat tcgtcacggg gagttggtat cgctggcatg ggaagatata gaccttaaag 4728 0 caaggactat aaccatccgt agaaattata caaaacttgg cgaattcact ccaccaaaaa 4734 0 ccgatgcagg caccggaagg acaattcatc tggttcaacc agctattgat gctcttaaaa 4740 0 gccaggcgga aatgaccatg cttggaaagc aacattctgt agaggtgaag cagagggaat 4746 0 atgggagaac tgctgtgcat aaatgcactt ttgtttttag tcctcaggta acaaaacagc 4752 0 agcagttgtc cggacctcac tacaaggttg actccatcag ggagtcatgg acaagtatct 4758 0 taaaacgcgc aggtctgaga cacagaaaat cgtaccaatc caggcatact tatgcatgct 4764 0 ggtcacttgc cgcaggagct aatcctagtt ttatcgcaag ccagatgggc cacacaaacg 4770 0 cacaaatggt attcaatgtt tacggagcat ggatgaaaga caacaatcac gaacagatag 4776 0 aactccttaa caaaagacta tctgaaagtg tcccatgtat gccccataag aaagcagggt 4782 0 aaaataaaaa cttgcaaaat caattagttt acccttaatc cctgtcacgt tacgcgcgt 4787 9 <210> 555 <211> 83 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(226..474) <400> 555 Met Arg Val Glu Ile Cys Ile Ala Lys Glu Lys Ile Thr Lys Met Pro 1 5 10 15 Asn Gly Ala Val Asp Ala Leu Lys Glu Glu Leu Thr Arg Arg Ile Ser 20 25 30 Lys Arg Tyr Asp Asp Val Glu Val Ile Val Lys Ala Thr Ser Asn Asp 35 40 45 Gly Leu Ser Val Thr Arg Thr Ala Asp Lys Asp Ser Ala Lys Thr Phe 50 55 60 Val Gln Glu Thr Leu Lys Asp Thr Trp Glu Ser Ala Asp Glu Trp Phe 65 70 75 80 Val Arg * <210> 556 <211> 103 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(842..1150) <400> 556 Met Lys Trp Ala Val Ile Gln Ala Glu Gln Glu Asn Asp Met Asn Ile 1 5 10 15 Leu Lys Lys Leu Met Gln Arg Leu Cys Gly Cys Gly Lys His Asp Gly 20 25 30 Arg Glu His Gly Gln Ser Leu Thr Ala Gln Leu Arg Leu Gly Pro Ala 35 40 45 Asp Ile Leu Glu Ser Asp Glu Asn Gly Ile Ile Pro Glu Gln Asp Arg 50 55 60 Val Ile Thr Gln Val Val Ile Leu Asp Ala Asp Lys Lys Gln Ile Gln 65 70 75 80 Cys Val Val Arg Pro Leu Gln Ile Leu Arg Ala Asp Gly Thr Trp Glu 85 90 95 Asn Ile Gly Gly Met Lys * 100 <210> 557 <211> 438 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1113..2426) <400> 557 Met Ala Val Lys Ile Ser Gly Val Leu Lys Asp Gly Thr Gly Lys Pro 1 5 10 15 Val Glu Asn Cys Thr Ile Gln Leu Lys Ala Arg Arg Asn Ser Ala Thr 20 25 30 Val Val Val Asn Thr Val Ala Ser Glu Asn Pro Asp Glu Ala Gly Arg 35 40 45 Tyr Ser Met Asp Val Glu Tyr Gly Gln Tyr Ser Val Ile Leu Leu Val 50 55 60 Glu Gly Phe Pro Pro Ser His Ala Gly Thr Ile Thr Val Tyr Glu Asp 65 70 75 80 Ser Gln Pro Gly Thr Leu Asn Asp Phe Leu Gly Ala Met Ser Glu Asp 85 90 95 Asp Val Arg Pro Glu Ala Leu Arg Arg Phe Glu Leu Met Val Glu Glu 100 105 110 Ala Ala Arg His Ala Glu Glu Ala Lys Lys Asn Ala Gly Glu Ala Glu 115 120 125 Thr Ser Ala Arg Asn Ala Gly Ile Ser Ala Ser Gln Ala Glu Glu Ser 130 135 140 Ala Ala Asn Ala Asp Thr Ser Ala Gly Asp Ala Leu Glu Ser Ala Arg 145 150 155 160 Gln Ala Ala Glu Ser Ala Ala Ala Ala Lys Gln Ser Glu Asp Ala Ser 165 170 175 Ser Ser Ser Ala Ser Ala Ala Ala Gln Lys Ala Ser Glu Ser Ser Gln 180 185 190 Ser Ala Ala Glu Ala Glu Leu Ser Arg Lys Thr Ala Glu Ser Ala Ala 195 200 205 Gly Asn Ala Ala Arg Asp Ala Thr Thr Ala Thr Glu Lys Ala Arg Glu 210 215 220 Ser Ala Glu Ser Ala Gln Ser Ala Glu Gln Ser Arg Ile Ala Ala Glu 225 230 235 240 Glu Ala Val Asn Arg Ile Pro Thr Val Val Gly Pro Pro Gly Pro Lys 245 250 255 Gly Glu Gln Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp Lys Gly 260 265 270 Glu Arg Gly Asp Thr Gly Pro Val Gly Ala Thr Gly Glu Arg Gly Pro 275 280 285 Ala Gly Asp Ala Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp Arg 290 295 300 Gly Glu Arg Gly Glu Thr Gly Leu Thr Gly Asn Ala Gly Pro Gln Gly 305 310 315 320 Pro Lys Gly Asp Thr Gly Ala Ala Gly Pro Ala Gly Pro Gln Gly Pro 325 330 335 Lys Gly Glu Thr Gly Ala Ala Gly Pro Val Gly Ala Thr Gly Pro Gln 340 345 350 Gly Pro Lys Gly Asp Pro Gly Glu Thr Gln Ile Arg Phe Arg Leu Gly 355 360 365 Pro Ala Ser Ile Ile Glu Thr Asn Ser Asn Gly Trp Phe Pro Asp Thr 370 375 380 Asp Gly Ala Leu Ile Thr Gly Leu Thr Phe Leu Asp Pro Lys Asp Ala 385 390 395 400 Thr Gln Val Gln Gly Leu Phe Arg His Leu Gln Val Arg Phe Gly Asp 405 410 415 Gly Pro Trp Gln Asp Val Lys Gly Leu Asp Glu Val Gly Ser Asp Thr 420 425 430 Gly Arg Thr Gly Glu * 435 <210> 558 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2491..3090) <400> 558 Met Arg Lys Leu Cys Ala Val Ile Leu Ser Ala Val Val Trp Gln Val 1 5 10 15 Ala Ala Ala Thr Pro Ala Ser Ala Ala Glu His Gln Ser Thr Leu Ser 20 25 30 Ala Gly Tyr Leu His Ala Ser Thr Asn Val Pro Gly Ser Asp Asp Leu 35 40 45 Asn Gly Ile Asn Val Lys Tyr Arg Tyr Glu Phe Met Asp Ala Leu Gly 50 55 60 Leu Ile Thr Ser Phe Ser Tyr Ala Asn Ala Glu Asp Glu Gln Lys Thr 65 70 75 80 Arg Tyr Ser Asp Thr Arg Trp His Glu Asp Ser Val Arg Asn Arg Trp 85 90 95 Phe Ser Val Met Ala Gly Pro Ser Val Arg Val Asn Glu Trp Phe Ser 100 105 110 Ala Tyr Ala Met Ala Gly Val Ala Tyr Ser Arg Val Ser Thr Phe Ser 115 120 125 Gly Asp Tyr Leu Arg Val Thr Asp Asn Lys Gly Lys Thr His Asp Val 130 135 140 Leu Thr Gly Ser Asp Asp Gly Arg His Ser Asn Thr Ser Leu Ala Trp 145 150 155 160 Gly Ala Gly Val Gln Phe Asn Pro Thr Glu Ser Val Ala Ile Asp Ile 165 170 175 Ala Tyr Glu Gly Ser Gly Ser Gly Asp Trp Arg Thr Asp Gly Phe Ile 180 185 190 Val Gly Val Gly Tyr Lys Phe * 195 <210> 559 <211> 776 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3158..5485) <400> 559 Val Gly Phe Arg Tyr Ser Phe Ser Ala Leu Lys Asp Arg His Thr Ala 1 5 10 15 Val Glu Val Asn Tyr Thr Asp Pro Gln Asn Gly Trp Gln Thr Ser Thr 20 25 30 Glu Leu Val Glu Asp Pro Glu Ala Ile Leu Arg Tyr Gly Arg Asn Leu 35 40 45 Leu Lys Met Asp Ala Phe Gly Cys Thr Ser Arg Gly Gln Ala His Arg 50 55 60 Ala Gly Leu Trp Val Ile Lys Thr Gly Leu Leu Glu Thr Gln Thr Val 65 70 75 80 Asp Phe Thr Leu Gly Ser Gln Gly Leu Arg His Thr Pro Gly Asp Ile 85 90 95 Ile Glu Ile Cys Asp Asn Asp Tyr Ala Gly Thr Met Thr Gly Gly Arg 100 105 110 Val Leu Ser Ile Asp Ala Ala Ser Arg Thr Leu Thr Leu Asp Arg Glu 115 120 125 Val Thr Leu Pro Glu Thr Gly Ala Ala Thr Val Asn Leu Ile Asn Gly 130 135 140 Ser Gly Lys Pro Val Ser Val Asp Ile Thr Ala His Pro Ala Pro Asp 145 150 155 160 Arg Ile Gln Val Ser Thr Leu Pro Asp Gly Val Glu Thr Tyr Gly Val 165 170 175 Trp Gly Leu Ser Leu Pro Ser Leu Cys Arg Arg Leu Phe Arg Cys Val 180 185 190 Ser Val Arg Glu Asn Thr Asp Gly Thr Phe Ala Ile Thr Ala Val Gln 195 200 205 His Val Pro Glu Lys Glu Ala Ile Val Asp Asn Gly Ala Arg Phe Glu 210 215 220 Pro Gln Ser Gly Ser Leu Asn Ser Val Ile Pro Pro Ala Val Gln His 225 230 235 240 Leu Thr Val Glu Val Ser Ala Ala Asp Gly Gln Tyr Leu Ala Gln Ala 245 250 255 Lys Trp Asp Thr Pro Arg Val Val Lys Gly Val Arg Phe Ser Leu Arg 260 265 270 Leu Thr Ser Gly Lys Gly Thr Asp Ala Arg Leu Val Thr Thr Ala Ile 275 280 285 Thr Ala Asp Thr Glu His Arg Phe Ser Gly Leu Pro Leu Gly Glu Tyr 290 295 300 Thr Leu Thr Val Arg Ala Ile Asn Ser Tyr Gly Gln Gln Gly Glu Pro 305 310 315 320 Ala Thr Thr Thr Phe Arg Ile Ala Ala Pro Ala Ala Pro Ser Arg Ile 325 330 335 Glu Leu Thr Pro Gly Tyr Phe Gln Ile Thr Ala Thr Pro His Leu Ala 340 345 350 Val Tyr Asp Pro Thr Val Gln Phe Glu Phe Trp Phe Ser Glu Lys Arg 355 360 365 Ile Ala Asp Ile Arg Gln Val Glu Thr Ala Ala Arg Tyr Leu Gly Ser 370 375 380 Ala Leu Tyr Trp Ile Ala Ala Ser Ile Asn Ile Lys Pro Gly His Asp 385 390 395 400 Tyr Tyr Phe Tyr Ile Arg Ser Val Asn Thr Val Gly Lys Ser Ala Phe 405 410 415 Val Glu Ala Val Gly Arg Ala Ser Asp Asp Ala Glu Gly Tyr Leu Asp 420 425 430 Phe Phe Lys Gly Glu Ile Gly Lys Thr His Leu Ala Gln Glu Leu Trp 435 440 445 Thr Gln Ile Asp Asn Gly Gln Leu Ala Pro Asp Leu Ala Glu Ile Arg 450 455 460 Thr Ser Ile Thr Asn Val Ser Asn Glu Ile Thr Gln Thr Val Asn Lys 465 470 475 480 Lys Leu Glu Asn Gln Ser Ala Ala Ile Gln Gln Ile Gln Lys Val Gln 485 490 495 Val Asp Thr Asn Asn Asn Leu Asn Ser Met Trp Ala Val Lys Leu Gln 500 505 510 Gln Met Gln Asp Gly Arg Leu Tyr Ile Ala Gly Ile Gly Ala Gly Ile 515 520 525 Glu Asn Thr Pro Ala Gly Met Gln Ser Gln Val Leu Leu Ala Ala Asp 530 535 540 Arg Ile Ala Met Ile Asn Pro Ala Asn Gly Asn Thr Lys Pro Met Phe 545 550 555 560 Val Gly Gln Gly Asp Gln Ile Phe Met Asn Glu Val Phe Leu Lys Tyr 565 570 575 Leu Thr Ala Pro Thr Ile Thr Ser Gly Gly Asn Pro Pro Ala Phe Ser 580 585 590 Leu Thr Pro Asp Gly Arg Leu Thr Ala Lys Asn Ala Asp Ile Ser Gly 595 600 605 Asn Val Asn Ala Asn Ser Gly Thr Leu Asn Asn Val Thr Ile Asn Glu 610 615 620 Asn Cys Arg Val Leu Gly Lys Leu Ser Ala Asn Gln Ile Glu Gly Asp 625 630 635 640 Leu Val Lys Thr Val Gly Lys Ala Phe Pro Arg Asp Ser Arg Ala Pro 645 650 655 Glu Arg Trp Pro Ser Gly Thr Ile Thr Val Arg Val Tyr Asp Asp Gln 660 665 670 Pro Phe Asp Arg Gln Ile Val Ile Pro Ala Val Ala Phe Ser Gly Ala 675 680 685 Lys His Glu Lys Glu His Thr Asp Ile Tyr Ser Ser Cys Arg Leu Ile 690 695 700 Val Arg Lys Asn Gly Ala Glu Ile Tyr Asn Arg Thr Ala Leu Asp Asn 705 710 715 720 Thr Leu Ile Tyr Ser Gly Val Ile Asp Met Pro Ala Gly His Gly His 725 730 735 Met Thr Leu Glu Phe Ser Val Ser Ala Trp Leu Val Asn Asn Trp Tyr 740 745 750 Pro Thr Ala Ser Ile Ser Asp Leu Leu Val Val Val Met Lys Lys Ala 755 760 765 Thr Ala Gly Ile Thr Ile Ser * 770 775 <210> 560 <211> 392 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5455..6630) <400> 560 Val Gly Lys Gly Gly Gly Lys Gly His Thr Pro Val Glu Ala Lys Asp 1 5 10 15 Asn Leu Lys Ser Thr Gln Met Met Ser Val Ile Asp Ala Ile Gly Glu 20 25 30 Gly Pro Ile Glu Gly Pro Val Lys Gly Leu Gln Ser Ile Leu Val Asn 35 40 45 Lys Thr Pro Leu Thr Asp Thr Asp Gly Asn Pro Val Ile His Gly Val 50 55 60 Thr Ala Val Trp Arg Ala Gly Glu Gln Glu Gln Thr Pro Pro Glu Gly 65 70 75 80 Phe Glu Ser Ser Gly Ser Glu Thr Ala Leu Gly Val Glu Val Thr Lys 85 90 95 Ala Lys Pro Val Thr Arg Thr Ile Thr Ser Ala Asn Ile Asp Arg Leu 100 105 110 Arg Val Thr Phe Gly Val Gln Ser Leu Val Gln Thr Thr Ser Gln Gly 115 120 125 Asp Arg Asn Pro Ala Ser Val Arg Leu Leu Ile Gln Leu Gln Arg Asn 130 135 140 Gly Asn Trp Val Thr Glu Lys Asp Val Thr Ile Asn Gly Lys Thr Thr 145 150 155 160 Ser Gln Phe Leu Ala Ser Val Ile Leu Asp Asn Leu Pro Pro Arg Pro 165 170 175 Phe Asn Ile Arg Met Val Arg Glu Thr Ala Asp Ser Thr Thr Asp Gln 180 185 190 Leu Gln Asn Arg Thr Leu Trp Ser Ser Tyr Thr Glu Ile Ile Asp Val 195 200 205 Lys Gln Cys Tyr Pro Asn Thr Ala Ile Val Gly Leu Gln Val Asp Ala 210 215 220 Glu Gln Phe Gly Gly Gln Gln Met Thr Val Asn Tyr His Ile Arg Gly 225 230 235 240 Arg Ile Ile Gln Val Pro Ser Asn Tyr Asp Pro Glu Lys Arg Thr Tyr 245 250 255 Ser Gly Ile Trp Asp Gly Ser Leu Lys Pro Ala Tyr Ser Asn Asn Pro 260 265 270 Ala Trp Cys Leu Trp Asp Met Leu Thr His Pro Arg Tyr Gly Met Gly 275 280 285 Lys Arg Leu Gly Ala Ala Asp Val Asp Lys Trp Ala Leu Tyr Ala Ile 290 295 300 Ala Gln Tyr Cys Asp Gln Thr Val Pro Asp Gly Phe Gly Gly Thr Glu 305 310 315 320 Pro Arg Met Thr Phe Asn Ala Tyr Leu Ser Gln Gln Arg Lys Ala Trp 325 330 335 Asp Val Leu Ser Asp Phe Cys Ser Ala Met Arg Cys Met Pro Val Trp 340 345 350 Asn Gly Gln Thr Leu Thr Phe Val Gln Asp Arg Pro Ser Asp Val Val 355 360 365 Trp Pro Thr Pro Ala Val Met Trp Trp Trp Met Ile Thr Ala Trp Gly 370 375 380 Phe Ala Thr Ala Ser Ala Pro * 385 390 <210> 561 <211> 226 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6871..7548) <400> 561 Met Ala Thr Thr Asn Ala Phe Cys Leu Ala Ser Pro Pro Leu Ala Arg 1 5 10 15 Ile Cys Leu His Gly Asp Leu Gln Arg Phe Gly Arg Arg Leu Ser Leu 20 25 30 Tyr Val Asn Thr Ala Ala Glu Ala Ile Arg Ala Leu Ser Leu Gln Met 35 40 45 Pro Gly Phe Arg Arg Gln Met Asn Glu Gly Trp Tyr Gln Ile Arg Ile 50 55 60 Arg Gly Glu Asp Thr Ala Pro Glu Ala Val Tyr Ala Arg Leu His Glu 65 70 75 80 Pro Leu Gly Glu Gly Ala Val Ile His Ile Val Pro Arg Leu Ala Gly 85 90 95 Ala Gly Lys Gly Gly Leu Gln Ile Val Leu Gly Ala Ala Ala Ile Val 100 105 110 Gly Ser Phe Phe Thr Ala Gly Ala Thr Met Ala Leu Trp Gly Ala Ala 115 120 125 Leu Ser Ala Gly Gly Leu Thr Ala Thr Thr Met Leu Phe Ser Leu Gly 130 135 140 Ala Ser Met Ile Leu Gly Gly Val Ala Gln Met Leu Ala Pro Lys Ala 145 150 155 160 Lys Thr Pro Glu Tyr Arg Ala Thr Asp Asn Gly Lys Gln Asn Thr Tyr 165 170 175 Phe Ser Ser Leu Asp Asn Met Ile Ala Gln Gly Asn Pro Met Pro Val 180 185 190 Pro Tyr Gly Glu Met Leu Val Gly Ser Arg Arg Ile Ser Gln Asp Ile 195 200 205 Ser Thr Arg Asp Glu Gly Gly Asp Gly Lys Val Val Val Ile Gly Arg 210 215 220 Gly * 225 <210> 562 <211> 248 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7446..8189) <400> 562 Met Thr Gln Thr Glu Ser Ala Ile Leu Val His Ala Arg Arg Cys Ala 1 5 10 15 Pro Ala Glu Ser Cys Gly Phe Val Ile Gly Thr Pro Glu Gly Glu Arg 20 25 30 Tyr Gln Pro Cys Val Asn Ile Ser Ala Glu Pro Glu Ala Tyr Phe Arg 35 40 45 Ile Ala Pro Glu Asp Trp Leu Gln Ala Glu Met Gln Gly Glu Ile Val 50 55 60 Ala Leu Val His Ser His Pro Gly Gly Leu Pro Trp Leu Ser Glu Ala 65 70 75 80 Asp Arg Arg Leu Gln Ile Lys Ser Ala Leu Pro Trp Trp Leu Val Cys 85 90 95 Arg Gly Glu Ile His Lys Phe Arg Cys Val Pro His Leu Thr Gly Arg 100 105 110 Arg Phe Glu His Gly Val Thr Asp Cys Tyr Thr Leu Phe Arg Asp Ala 115 120 125 Tyr His Leu Ala Gly Ile Thr Leu Pro Asp Phe Glu Arg Glu Asp Asp 130 135 140 Trp Trp Arg Asn Gly Gln Asn Leu Tyr Leu Asp Asn Met Ala Ala Thr 145 150 155 160 Gly Phe Tyr Arg Val Pro Leu Ser Ser Ala Gln Ala Gly Asp Ile Leu 165 170 175 Leu Cys Cys Phe Gly Ala Ser Val Ala Asn His Ala Ala Ile Tyr Cys 180 185 190 Gly Asn Gly Glu Leu Leu His His Leu Pro Glu Gln Leu Ser Lys Arg 195 200 205 Glu Arg Tyr Ser Glu Lys Trp Gln Arg Arg Thr His Ser Val Trp Arg 210 215 220 His Arg His Trp His Ala Ser Ala Phe Thr Gly Ile Cys Asn Asp Leu 225 230 235 240 Ala Ala Ala Ser Ala Cys Thr * 245 <210> 563 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8200..8898) <400> 563 Met Gln Asp Ile His Gly Glu Ser Leu Ile Glu Ser Val Lys Ser Glu 1 5 10 15 Gln Ser Pro Arg Val Val Leu Trp Glu Ile Asp Leu Thr Val Gln Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Leu Asn Glu Lys Gly Glu Ala 35 40 45 Val Thr Trp Gln Gly Arg Glu Tyr Gln Ala Tyr Pro Ile Asp Gly Ser 50 55 60 Gly Phe Glu Met Asn Gly Lys Gly Ser Ser Ala Arg Pro Ser Leu Thr 65 70 75 80 Val Ser Asn Leu Phe Gly Leu Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Ala Thr Val Val Arg Arg Arg Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Ala Gly Asn Pro Glu Ala Asp Pro Glu 115 120 125 Gln Glu Leu Ser Asp Arg Trp Val Val Glu Gln Met Ser Glu Leu Thr 130 135 140 Ala Met Thr Ala Ser Phe Val Leu Ala Thr Pro Thr Glu Thr Asp Gly 145 150 155 160 Ala Leu Phe Pro Gly Arg Ile Met Leu Ala Asn Thr Cys Met Trp Asp 165 170 175 Tyr Arg Gly Asp Glu Cys Gly Tyr Asn Gly Pro Ala Val Ala Asp Glu 180 185 190 Phe Asp Asn Pro Thr Thr Asp Ile Arg Lys Asp Arg Cys Ser Lys Cys 195 200 205 Met Arg Gly Cys Glu Met Arg Gly Met Val Ala Asn Phe Gly Gly Phe 210 215 220 Leu Ser Ile Asn Lys Leu Ser Gln * 225 230 <210> 564 <211> 110 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8898..9227) <400> 564 Met Lys Thr Phe Arg Trp Lys Val Lys Pro Asp Met Glu Val Asn Ser 1 5 10 15 Gln Pro Ser Val Arg Glu Val Arg Phe Gly Asp Gly Tyr Ser Gln Arg 20 25 30 Met Ala Ala Gly Leu Asn Ala Asp Leu Lys Thr Tyr Arg Val Thr Leu 35 40 45 Ser Val Thr Arg Glu Glu Ala Arg His Leu Glu Ala Phe Leu Ala Glu 50 55 60 His Gly Gly Trp Lys Ala Phe Leu Trp Lys Pro Pro Tyr Ala Tyr Arg 65 70 75 80 Gln Ile Lys Val Thr Cys Ala Gly Trp Ser Ala Arg Val Gly Met Leu 85 90 95 Arg Val Glu Phe Ser Ala Glu Phe Lys Gln Val Val Asn * 100 105 <210> 565 <211> 882 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9224..11869) <400> 565 Met Ala Gly Asn Phe Ala Asp Leu Thr Ala Val Leu Thr Leu Asp Ser 1 5 10 15 Ala Arg Phe Ser Glu Glu Ala Ala Arg Val Lys Lys Glu Leu Gly Glu 20 25 30 Thr Ser Ala Leu Ala Asp Leu Met Ser Gly Lys Val Ser Gln Ser Phe 35 40 45 Arg Lys Gln Ala Asp Ala Ala Glu Gln Ser Leu Ser Arg Gln Ala Leu 50 55 60 Ala Ala Gln Lys Ala Gly Ile Ser Val Gly Gln Tyr Lys Ala Ala Met 65 70 75 80 Arg Thr Leu Pro Ala Gln Phe Thr Asp Ile Val Thr Gln Leu Ala Gly 85 90 95 Gly Gln Asn Pro Phe Leu Ile Met Leu Gln Gln Gly Gly Gln Ile Ser 100 105 110 Asp Ser Phe Gly Gly Pro Leu Ser Leu Leu Thr Leu Leu Lys Glu Glu 115 120 125 Leu Leu Gly Ile Arg Asp Ala Ser Glu Ser Ser Glu Glu Ser Leu Ser 130 135 140 Asp Thr Ala Asn Ala Leu Ala Glu Asn Ala Arg Asn Ala Gly Glu Leu 145 150 155 160 Gly Arg Phe Met Ser Val Ala Arg Val Ala Ala Gly Gly Gly Val Ala 165 170 175 Val Leu Ala Ala Leu Ala Ala Ala Ala Trp Gln Ala Glu Gln Ala Asp 180 185 190 Arg Ala Leu Leu Arg Ser Leu Thr Leu Thr Gly Gly Ala Ala Ala Thr 195 200 205 Thr Thr Ala Glu Leu Trp Lys Met Ala Gly Val Ile Ser Asp Glu Ala 210 215 220 Gly Gly Gly Ile Arg Gln Ala Ala Glu Asn Leu Ala Arg Leu Ala Glu 225 230 235 240 Ser Gly Lys Tyr Thr Ala Gly Gln Leu Arg Ile Met Gly Glu Thr Ser 245 250 255 Gln Arg Trp Leu Gln Thr Val Gly Asp Asp Ala Gly Lys Val Glu Lys 260 265 270 Ala Phe Glu Gly Ile Ala Ala Asp Pro Val Lys Ala Leu Ala Ser Leu 275 280 285 Asn Gln Gln Tyr Asn Phe Leu Ser Val Ser Gln Leu Arg His Ile Asp 290 295 300 Glu Leu Glu Arg Thr Lys Gly Lys Gln Ala Ala Val Thr Glu Ala Met 305 310 315 320 Ser Leu Phe Ala Asp Val Met Asn Ala Arg Leu Glu Gln Leu Asp Lys 325 330 335 Ala Ala Thr Pro Val Glu Lys Ile Trp Asp Asp Val Lys Thr Trp Thr 340 345 350 Ser Asp Ala Trp Ala Trp Ile Gly Asp His Thr Leu Gly Ala Leu Ser 355 360 365 Leu Ile Thr Asp Val Val Ala Gly Thr Val Glu Gln Val Lys Leu Leu 370 375 380 Leu Val Gln Gly Asp Leu Ala Leu Ala Glu Phe Ile Gln Ser Ala Trp 385 390 395 400 Glu Thr Thr Lys Asn Val Pro Gly Val Gly Ala Leu Phe Gly Glu Leu 405 410 415 Ala Glu Glu Asn Arg Val Phe Ile Glu Lys Thr Lys Arg Asp Glu Leu 420 425 430 Ala Leu Arg Lys Ser Ile Ala Glu Arg Asp Ala Arg Ile Arg Gln Gly 435 440 445 Glu Met Gly Tyr Ile Asn Arg Ser Arg Ala Thr Gly Val Ser Lys Gly 450 455 460 Pro Gly Gln Gln Glu Ala Val Ser Arg Leu Ala Glu Glu Leu Thr Gly 465 470 475 480 Lys Lys His Thr Ser Pro Lys Thr Arg Ser Ala Gly Glu Arg Glu Glu 485 490 495 Glu Gln Ala Arg Glu Ala Leu Leu Ala Leu Glu Ala Glu Leu Arg Thr 500 505 510 Leu Glu Lys His Ser Gly Ala Asn Glu Lys Ile Ser Arg Gln Arg Arg 515 520 525 Asp Leu Trp Lys Ala Glu Ser Gln Tyr Ala Val Leu Lys Glu Ala Ala 530 535 540 Thr Lys Arg Gln Leu Ser Glu Gln Glu Lys Ser Leu Leu Ala His Lys 545 550 555 560 Asp Glu Thr Leu Glu Tyr Lys Arg Gln Leu Ala Glu Leu Gly Asp Lys 565 570 575 Val Glu Tyr Gln Lys Arg Leu Asn Glu Leu Ala Gln Gln Ala Val Arg 580 585 590 Phe Glu Glu Gln Gln Ser Ala Lys Gln Ala Ala Ile Ser Ala Lys Ala 595 600 605 Arg Gly Leu Thr Asp Arg Gln Ala Gln Arg Glu Ser Glu Ala Gln Arg 610 615 620 Leu Arg Asp Val Tyr Gly Asp Asn Pro Ala Ala Leu Ala Lys Ala Thr 625 630 635 640 Ser Ala Leu Lys Asn Thr Trp Ser Ala Glu Glu Gln Leu Arg Gly Ser 645 650 655 Trp Met Ala Gly Leu Lys Ser Gly Trp Gly Glu Trp Ala Glu Ser Ala 660 665 670 Thr Asp Ser Phe Ser Gln Val Lys Ser Ala Ala Thr Gln Thr Phe Asp 675 680 685 Gly Ile Ala Gln Asn Met Ala Ala Met Leu Thr Gly Ala Glu Ala Asp 690 695 700 Trp Arg Gly Phe Thr Arg Ser Val Leu Ser Met Met Thr Glu Ile Leu 705 710 715 720 Leu Lys Gln Ala Met Val Gly Ile Val Gly Arg Ile Gly Ser Ala Ile 725 730 735 Gly Gly Ala Phe Gly Gly Gly Ala Ser Ala Ser Thr Gly Thr Ala Ile 740 745 750 Gln Ala Ala Ala Ala Asn Phe His Phe Ala Thr Gly Gly Phe Thr Gly 755 760 765 Thr Gly Gly Lys Tyr Glu Pro Ala Gly Ile Val His Arg Gly Glu Phe 770 775 780 Val Phe Thr Lys Glu Ala Thr Ser Arg Ile Gly Val Gly Asn Leu Tyr 785 790 795 800 Arg Leu Met Arg Gly Tyr Ala Glu Gly Gly Tyr Val Gly Gly Ala Gly 805 810 815 Ser Pro Ala Gln Met Arg Arg Thr Glu Gly Ile Asn Phe Asn Gln Asn 820 825 830 Asn His Val Val Ile Gln Asn Asp Gly Thr Asn Gly Gln Ala Gly Pro 835 840 845 Gln Leu Met Lys Ala Val Tyr Asp Met Ala Arg Lys Gly Ala Gln Asp 850 855 860 Glu Leu Arg Leu Gln Leu Arg Asp Gly Gly Met Leu Ser Gly Ser Arg 865 870 875 880 Arg * <210> 566 <211> 103 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11913..12221) <400> 566 Met Gly Arg Ala Asp Trp Arg Ala Met Leu Ala Gly Met Thr Ser Thr 1 5 10 15 Glu Tyr Ala Asp Trp Arg Arg Phe Tyr Cys Thr His Tyr Phe Gln Asp 20 25 30 Thr Gln Leu Asp Met His Phe Ser Gly Leu Met Tyr Ala Val Leu Ser 35 40 45 Leu Phe Phe Cys Asp Pro Asp Met His Pro Ala Asp Phe Ser Leu Phe 50 55 60 Ala Pro Glu Ala Glu Glu Gly Gln Ala Glu Thr Pro Asp Glu Asn Asp 65 70 75 80 Val Leu Met Gln Lys Ala Ala Gly Leu Ala Gly Gly Val Arg Phe Gly 85 90 95 Glu Glu Gly Arg Arg Leu * 100 <210> 567 <211> 141 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12248..12670) <400> 567 Met Phe Leu Lys Thr Glu Gln Phe Glu Tyr Asn Gly Val Ser Val Thr 1 5 10 15 Leu Ser Glu Leu Ser Ala Leu Gln Arg Phe Asp Tyr Ile Lys Phe Val 20 25 30 Ser Asp Ala Glu Gln Gln Glu Thr Thr Lys His Asp Val Val His Ile 35 40 45 Asn Gln Arg Tyr Leu Glu Thr Ala Ser Leu Leu Val Ala Met Ser Leu 50 55 60 Trp His Ser His Ser Leu Lys Gly Thr Leu Ala Ser Pro Glu Thr Glu 65 70 75 80 Met Gln Gln Ile Arg Arg Glu Val Met Leu Gly Trp Pro Ala Asp Ala 85 90 95 Leu Asn Gln Ala Thr Asn Arg Val Leu Tyr Leu Ser Gly Met Leu Asp 100 105 110 Asn Arg His Asp Ala Asp Pro Glu Pro Thr Gly Lys Thr Glu Ala Thr 115 120 125 Glu Pro Val Thr Ser Lys Lys His Ser Lys Ala Ser * 130 135 140 <210> 568 <211> 251 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12684..13436) <400> 568 Met Ala Thr Pro Asn Pro Leu Glu Pro Val Lys Gly Ala Gly Thr Thr 1 5 10 15 Leu Trp Val Tyr Asn Gly Lys Gly Asp Ala Tyr Ala Asn Pro Leu Ser 20 25 30 Asp Asp Asp Trp Gln Arg Leu Ala Lys Val Lys Asp Leu Thr Pro Gly 35 40 45 Glu Met Thr Ala Glu Pro Tyr Asp Asp Asn Tyr Leu Asp Asp Glu Asp 50 55 60 Ala Asp Trp Thr Ala Thr Gly Gln Gly Gln Lys Ser Ala Gly Asp Thr 65 70 75 80 Ser Phe Thr Leu Ala Trp Lys Pro Gly Glu Glu Gly Gln Lys Gly Leu 85 90 95 Ile Gly Trp Phe Glu Ser Gly Asp Val Arg Ala Tyr Lys Ile Arg Phe 100 105 110 Pro Asn Gly Thr Val Asp Val Phe Arg Gly Trp Val Ser Ser Ile Gly 115 120 125 Lys Ala Val Thr Ala Lys Glu Val Ile Thr Arg Thr Val Lys Val Thr 130 135 140 Asn Val Gly Lys Pro Ser Val Ala Glu Glu Arg Ser Glu Ile Thr Pro 145 150 155 160 Ala Thr Ala Ile Lys Val Thr Pro Thr Ser Gly Thr Val Ala Lys Gly 165 170 175 Lys Thr Thr Thr Leu Thr Val Ser Phe Glu Pro Glu Ser Ala Thr Asp 180 185 190 Lys Thr Phe Arg Ala Val Ser Ala Asp Pro Ser Lys Ala Thr Ile Ser 195 200 205 Val Lys Asp Met Thr Ile Thr Val Asn Gly Val Ala Thr Gly Lys Val 210 215 220 Gln Ile Pro Val Val Ser Gly Asn Gly Gln Phe Ala Ala Val Ala Glu 225 230 235 240 Val Thr Val Thr Glu Ala Gly Ala Ala Gly * 245 250 <210> 569 <211> 133 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13444..13842) <400> 569 Met Lys His Arg Glu Ile Arg Ala Ala Val Leu Ser Ala Leu Lys Glu 1 5 10 15 Asn Ile Ser Glu Arg Val Ser Trp Phe Asp Gly Arg Pro Val Phe Ile 20 25 30 Asp Glu Gln Glu Leu Pro Ala Val Ala Val Tyr Leu Thr Asp Ala Ser 35 40 45 Ala Ala Asp Glu Phe Val Asp Glu Gly Thr Trp Glu Ala Thr Leu His 50 55 60 Ile Glu Val Phe Leu Arg Ala Lys Glu Pro Asp Ser Ala Leu Asp Met 65 70 75 80 Trp Met Glu Glu Lys Ile Leu Pro Ala Leu Glu Ala Val Pro Gly Leu 85 90 95 Ser Ala Leu Leu Leu Lys Met Asn Leu Gln Gly Tyr Asp Tyr Arg Arg 100 105 110 Asp Asp Glu Phe Met Met Trp Gly Ser Ala Asp Leu Leu Trp Lys Ile 115 120 125 Thr Tyr Glu Met * 130 <210> 570 <211> 208 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13855..14478) <400> 570 Met Ala Ile Lys Gly Leu Ala Gln Ala Met Lys Asn Leu Asp Ala Ile 1 5 10 15 Asp Arg Arg Ala Val Pro Arg Ala Ser Ala Thr Thr Leu Asn Arg Val 20 25 30 Ala Gly Ala Ile Ile Ala Lys Thr Ala Ser Ser Val Ala Arg Glu Leu 35 40 45 Ala Val Pro Arg Arg Leu Ile Arg Ala Arg Ile Arg Leu Ser Pro Ala 50 55 60 Arg Pro Asp Lys Val Tyr Ala Lys Val Tyr Ile Asn Thr Gly Asn Leu 65 70 75 80 Pro Ala Ile Lys Leu Gly Glu Ala Arg Val Arg Leu Ser Arg Arg Lys 85 90 95 Arg Arg Lys Lys Gly Gln Arg Ala Ala Leu Lys Gly Gly Gly Ser Val 100 105 110 Leu Ile Val Gly Lys Arg Arg Ile Pro Asp Ala Phe Ile Thr Arg Leu 115 120 125 Ala Asn Gly Arg Trp His Val Met Gln Arg Met Pro Trp Ala Ser Ser 130 135 140 Ser Thr Gly Ala Asp Ser Lys Gly Arg Pro Lys Arg His Arg Leu Pro 145 150 155 160 Ile Glu Val Val Lys Ile Thr Thr Ala Gly Pro Leu Ala Glu Thr Phe 165 170 175 Glu Arg Glu Arg Asp Arg Met Tyr Arg Glu Lys Leu Pro Ala Gln Met 180 185 190 Met Lys Ala Met Thr His Gln Leu Arg Leu Val Leu Lys Arg Lys * 195 200 205 <210> 571 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14481..14762) <400> 571 Met Ser Asp Leu Phe Thr Arg Met Cys Cys Arg Met Asp Val Ala Thr 1 5 10 15 Val Arg Val Met Gly Lys Gln Ala Glu Ile Asn Gly Val Val Tyr Asp 20 25 30 Val Met Pro Glu Glu Glu Ser Ala Glu Met Gly Ala Leu Ser Gly Ser 35 40 45 Gln Leu Ser Leu Val Val Phe Ser Ala Arg Tyr Arg Pro Ala Arg His 50 55 60 Asp Val Val Val Phe Ala Gly Arg Thr Leu Thr Val Thr Arg Tyr Asp 65 70 75 80 Thr Tyr Asn Gly Lys Pro Arg Ile Phe Val Glu Gln Glu * 85 90 <210> 572 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14755..15081) <400> 572 Met Ala Lys Asn Phe Val Gln Asp Gly Thr Thr Ile Glu Leu Val Asn 1 5 10 15 Ala Gly Asp Gln Thr Ile Leu Ser Gly Ala Ala Val Val Val Gly Ser 20 25 30 Met Val Ala Val Ala Ile Thr Asp Ile Pro Ala Gly Glu Ala Gly Asp 35 40 45 Gly Phe Ala Glu Gly Val Phe Leu Leu Pro Lys Gln Ser Ala Asp Asp 50 55 60 Ile Gln Ser Gly Ala Val Val Tyr Leu Lys Asp Gly Val Val Gln Leu 65 70 75 80 Ala Ala Asp Gly Ala Val Ala Ala Gly Val Ala Trp Glu Asn Ala Pro 85 90 95 Ala Asn Ser Ala Thr Val Ala Val Lys Ile Asn Val * 100 105 <210> 573 <211> 339 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15169..16185) <400> 573 Met Leu Ala Arg Ala Gly Phe Glu Asn Val Glu Lys Asp Asn Ala Tyr 1 5 10 15 Asn Gly Met Thr Leu Arg Glu Trp Ala Arg Met Ser Leu Thr Glu Arg 20 25 30 Gly Ile Gly Val Ala Ser Tyr Asn Pro Met Gln Met Val Gly Leu Ala 35 40 45 Leu Thr His Ser Thr Ser Asp Phe Gly Asn Ile Leu Leu Asp Val Ser 50 55 60 Asn Lys Gly Leu Ile Gln Gly Trp Glu Glu Ser Glu Glu Thr Phe Gln 65 70 75 80 Lys Trp Thr Arg Lys Gly Arg Leu Ser Asp Phe Lys Thr Ala Tyr Arg 85 90 95 Val Gly Met Gly Gly Phe Gly Ser Leu Arg Gln Val Arg Glu Gly Ala 100 105 110 Glu Tyr Lys Tyr Ile Thr Thr Ser Asp Arg Lys Glu Thr Ile Ala Leu 115 120 125 Ala Thr Tyr Gly Glu Ile Phe Ser Ile Thr Arg Gln Ala Ile Ile Asn 130 135 140 Asp Asp Leu Asn Met Leu Val Asp Val Pro Met Lys Met Gly Arg Ala 145 150 155 160 Ala Lys Ala Thr Ile Gly Asp Leu Val Tyr Lys Val Leu Thr Asp Asn 165 170 175 Pro Lys Leu Ser Asp Gly Lys Ala Leu Phe His Ala Asp His Lys Asn 180 185 190 Ile Ala Thr Gly Gly Ile Ser Val Ser Gly Leu Asp Ala Ala Arg Gln 195 200 205 Met Met Arg Leu Gln Lys Glu Gly Asp Arg Ala Leu Asn Ile Arg Pro 210 215 220 Ala Phe Met Leu Val Pro Val Ala Leu Glu Thr Val Ala Asn Gln Thr 225 230 235 240 Ile Lys Ser Ala Ser Val Lys Gly Ala Asp Ala Asn Ala Gly Val Ile 245 250 255 Asn Pro Ile Gln Asn Phe Ala Glu Val Ile Ala Glu Ala Arg Leu Asp 260 265 270 Ala Ala Asp Pro Lys Thr Trp Tyr Leu Ala Ala Ala Gln Gly Thr Asp 275 280 285 Thr Ile Glu Val Ala Trp Leu Asp Gly Val Asp Thr Pro Tyr Ile Asp 290 295 300 Gln Gln Glu Gly Phe Thr Thr Asp Gly Ile Ala Thr Lys Ile Arg Ile 305 310 315 320 Asp Ala Gly Val Ala Pro Leu Asp Trp Arg Gly Leu Val Arg Ser Ser 325 330 335 Val Ala * <210> 574 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16331..16657) <400> 574 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Ser Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 575 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16654..17544) <400> 575 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 576 <211> 369 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17547..18653) <400> 576 Val Val Gln Arg Gln Asn Leu Thr Gly Cys Val Pro Val Gly Ala Ile 1 5 10 15 Arg Met Arg Ser Asn Val Ala Ala Arg Leu Lys Leu Met Lys Thr Ala 20 25 30 Asp Trp Gly Trp Ser Leu Ile Leu Thr Pro Ser Thr Thr Lys Glu Ala 35 40 45 Thr Val Pro Glu Leu Asn Asp Ser Ile Ser Ala Thr Pro Lys Ala Ser 50 55 60 Met Lys Asn Lys Ser Trp Phe Arg Met Gln Ala Gly Gly Pro Gly Asp 65 70 75 80 Ala Asp Ile Tyr Ile Tyr Asp Glu Ile Gly Phe Trp Gly Val Thr Ala 85 90 95 Lys Gln Phe Val Ser Glu Leu Asn Ala Leu Gly Asp Ile Thr His Ile 100 105 110 Asn Leu His Ile Asn Ser Pro Gly Gly Asp Val Phe Glu Gly Ile Ala 115 120 125 Ile Phe Asn Ala Leu Lys Asn Gln Gly Ala Thr Ile Thr Val Tyr Val 130 135 140 Asp Gly Val Ala Ala Ser Met Ala Ser Val Ile Ala Met Ala Gly Asp 145 150 155 160 Thr Val Ile Met Pro Glu Asn Ala Phe Met Met Ile His Lys Pro Trp 165 170 175 Gly Phe Ser Gly Gly Asp Ala Glu Asp Met Arg Ser Tyr Ala Asp Leu 180 185 190 Leu Asp Lys Val Glu Ser Val Leu Leu Pro Ala Tyr Ala Gln Lys Thr 195 200 205 Gly Lys Thr Thr Asp Glu Ile Ala Ala Met Leu Ala Asp Glu Thr Trp 210 215 220 Met Ser Gly Ala Glu Cys Leu Ala His Gly Phe Ala Asp Gln Val Thr 225 230 235 240 Pro Ala Val Glu Ala Met Ala Cys Ile Gln Ser Lys Arg Thr Glu Glu 245 250 255 Phe Lys Lys Met Pro Glu Ser Ile Arg Asn Met Ile Thr Pro Pro Arg 260 265 270 Asn Ser Ala Pro Arg Asp Thr Thr Val Thr Ile Pro Ala Pro Ala Val 275 280 285 Thr Glu Pro Ser Pro Val Pro Ala Val Ser Asp Glu Ala Thr Ile Arg 290 295 300 Ala Arg Val Met Ala Glu Gln Lys Ala Arg Met Ser Gly Ile Asn Asp 305 310 315 320 Leu Phe Ala Met Phe Gly Gly Arg Tyr Gln Thr Leu Gln Ala Gln Cys 325 330 335 Val Ala Asp Pro Asp Cys Ser Leu Glu Met Ala Arg Glu Arg Leu Leu 340 345 350 Asn Glu Met Gly Glu Pro Pro Arg Val Ser Trp Arg Val Phe Tyr Leu 355 360 365 * <210> 577 <211> 501 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18451..19953) <400> 577 Met Ala Ile Ile Asp Asp Val Ile Gly Val Phe Ser Pro Gly Trp Lys 1 5 10 15 Ala Ala Arg Leu Arg Ser Arg Ala Leu Ile Met Ala Tyr Glu Ala Val 20 25 30 Lys Pro Thr Arg Thr His Lys Ala Arg Arg Glu Asn Arg Ser Ala Asp 35 40 45 Gln Leu Ser Lys Tyr Gly Ala Val Ser Leu Arg Glu Gln Ala Arg Phe 50 55 60 Leu Asp Ile Asn His Asp Leu Val Ile Gly Val Phe Asp Lys Leu Glu 65 70 75 80 Glu Arg Val Ile Gly Ala Arg Gly Ile Ile Val Glu Pro Gln Pro Leu 85 90 95 Arg Lys Asn Gly Glu Met Ala Ala Glu Leu Ala Ala Asp Ile Arg Arg 100 105 110 Leu Trp Ala Glu Trp Ser Val Ser Pro Asp Val Thr Gly Gln Tyr Thr 115 120 125 Arg Pro Val Leu Glu Arg Leu Leu Leu Arg Thr Trp Leu Arg Asp Gly 130 135 140 Glu Val Phe Ala Gln Met Val Ser Gly Ala Gly Asn Gly Leu Glu Arg 145 150 155 160 Thr Ala Gly Val Pro Phe Trp Leu Glu Ala Met Glu Pro Asp Phe Val 165 170 175 Pro Met Arg Thr Asp Glu Ser Ala Gly Leu Asn Gln Gly Val Phe Leu 180 185 190 Asp Glu Trp Gly Arg Pro Lys Lys Tyr Leu Val Tyr Lys Asn Tyr Pro 195 200 205 Val Ser Gly Arg Gln Ser Asp Thr Lys Glu Ile Ala Ala Gly Lys Met 210 215 220 Ile His Leu Lys Phe Thr Arg Arg Leu His Gln Thr Arg Gly Ser Ser 225 230 235 240 Met Leu Ser Gly Val Leu Met Arg Ile Ser Ala Leu Lys Glu Tyr Glu 245 250 255 Asp Ala Glu Leu Thr Ala Ala Arg Ile Ala Ala Ala Leu Gly Leu Tyr 260 265 270 Ile Arg Lys Gly Asp Gly Gln Asp Tyr Glu Asp Pro Gly Ile Lys Glu 275 280 285 Thr Glu Arg Glu Val His Ile Thr Pro Gly Ile Ile Tyr Asp Asp Leu 290 295 300 Arg Lys Gly Glu Asp Ile Gly Met Val Lys Ser Asp Arg Pro Asn Pro 305 310 315 320 Asn Leu Glu Thr Phe Arg Asn Gly Gln Leu Arg Ala Val Ala Ala Gly 325 330 335 Ser Arg Leu Ser Phe Ser Ser Ala Ala Arg Asn Tyr Asn Gly Thr Tyr 340 345 350 Ser Ala Gln Arg Gln Glu Leu Val Glu Ser Thr Asp Gly Tyr Leu Ile 355 360 365 Leu Gln Asp Cys Phe Ile Gly Ala Val Thr Arg Pro Val Tyr Arg Thr 370 375 380 Trp Leu Asn Met Val Val Ala Ala Gly Leu Leu Lys Ile Pro Ala Asp 385 390 395 400 Val Glu Met Lys Thr Leu Tyr Asn Ala Thr Tyr Ser Gly Pro Val Met 405 410 415 Pro Trp Ile Asp Pro Val Lys Glu Ala Glu Ala Trp Arg Ile Gln Ile 420 425 430 Arg Gly Gly Ala Ala Thr Glu Ser Asp Trp Val Arg Ala Gly Gly Arg 435 440 445 Asn Pro Asp Glu Val Lys Arg Arg Arg Lys Ala Glu Ile Asp Glu Asn 450 455 460 Ser Arg Leu Gly Leu Val Phe Asp Thr Asp Pro Val Asn Asp Lys Gly 465 470 475 480 Gly Asn Ser Ala Gly Thr Glu Arg Gln Tyr Gln Arg Asp Thr Glu Ser 485 490 495 Gln His Glu Glu * 500 <210> 578 <211> 79 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19953..20189) <400> 578 Met Asp Asn Ile Arg Arg Leu Val Val Ser Thr Glu Glu Ala Arg Glu 1 5 10 15 Met Ile Gln Arg Tyr Arg Glu Ala Glu Met Ala Val Leu Glu Gly Lys 20 25 30 Ser Val Ile Phe Asn Gly Gln Gln Leu Thr Leu Glu Ser Leu Ser Gln 35 40 45 Ile Arg Ala Gly Arg Gln Glu Trp Glu Arg Arg Leu Ala Ala Met Val 50 55 60 Ser Arg Arg Arg Gly Lys Pro Gly Phe Lys Leu Ala Arg Phe * 65 70 75 <210> 579 <211> 708 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20162..22285) <400> 579 Val Asn Gln Val Asn Glu Ser His Ser Arg Ala Ser Asp Ile Trp Arg 1 5 10 15 Glu Val Ala Ser Leu Phe Arg Pro Pro Ser Arg Leu Pro Val Ala Glu 20 25 30 Ala Ile Arg Arg Tyr Met Arg Val Pro Arg Gly Ala Asn Thr Ser Gly 35 40 45 Pro Trp Glu Ser Ser Leu Thr Pro Tyr Met Ile Asp Pro Ile Asn Thr 50 55 60 Leu Ser Ala Arg Glu Tyr Asp Ala Val Val Phe Val Gly Pro Ala Arg 65 70 75 80 Thr Gly Lys Thr Glu Gly Leu Ile Asp Gly Trp Ile Val Tyr Gly Ile 85 90 95 Ile Cys Asp Pro Ala Asp Met Leu Val Val Gln Met Thr Glu Thr Lys 100 105 110 Ala Arg Glu His Ser Arg Thr Arg Leu Ser Arg Thr Phe Arg His Ser 115 120 125 Pro Glu Val Ser Lys Arg Leu Ser Pro Ser Arg Asn Asp Asn Asn Val 130 135 140 His Asp Lys Met Phe Leu Asp Gly Ser Phe Leu Lys Ile Gly Trp Pro 145 150 155 160 Ser Ile Thr Val Phe Ser Ser Ser Asp Tyr Arg Arg Val Ala Leu Thr 165 170 175 Asp Tyr Asp Arg Phe Pro Glu Asn Val Asp Gly Glu Gly Asp Ala Phe 180 185 190 Thr Leu Ala Ser Lys Arg Thr Thr Thr Phe Met Ser Ser Gly Met Thr 195 200 205 Leu Val Glu Ser Ser Pro Gly Arg Asp Ile Thr Asp Thr Lys Trp Arg 210 215 220 Cys Gly Gly Ala His Glu Ala Pro Pro Thr Thr Gly Ile Leu Ser Leu 225 230 235 240 Tyr Asn Arg Gly Asp Arg Arg Arg Trp Tyr Trp Pro Cys Pro His Cys 245 250 255 Gly Glu Tyr Phe Gln Pro Val Met Asp Asn Met Thr Gly Tyr Arg Asn 260 265 270 Asn Pro Asp Phe Val Ala Ala Gly Gln Ala Ala Arg Leu Met Cys Pro 275 280 285 His Cys Arg Gly Leu Ile Ala Pro Glu Gln Lys Arg Glu Leu Asn Asn 290 295 300 Gln Gly Ile Trp Leu Arg Glu Gly Glu Arg Ala Ala Ala Asp Gly Ser 305 310 315 320 Ile Thr Gly Thr Pro Arg Asn Ser Arg Ile Ala Ser Phe Trp Met Glu 325 330 335 Gly Pro Ala Ala Ala Phe Gln Thr Trp Glu Gln Leu Ile Phe Lys Leu 340 345 350 Leu Ala Ala Glu Glu Glu Tyr Glu Arg Thr Gly Ser Glu Glu Thr Leu 355 360 365 Lys Ala Val Val Asn Thr Asp Ile Gly Arg Pro Tyr Leu Pro Arg Ser 370 375 380 Ala Thr Glu Gln Arg Lys Ser Glu Leu Leu Glu Gln Arg Ala Glu Pro 385 390 395 400 Phe Pro Arg Arg Ser Val Pro Asp Gly Val Arg Phe Ile Glu Ala Thr 405 410 415 Val Asp Val Gln Gly Gly Lys Asn Arg Arg Phe Val Val Gln Ile Thr 420 425 430 Gly Tyr Gly Glu Gln Gly Glu Arg Trp Ile Val Asp Arg Tyr Asn Ile 435 440 445 Arg His Ser Leu Arg Cys Ser Pro Asn Gly Glu Ser Leu Pro Val Asp 450 455 460 Pro Ala Ala Tyr Pro Glu Asp Trp Asp Leu Leu Leu Thr Asp Val Phe 465 470 475 480 His Lys Thr Trp Pro Leu Ala Ser Asp Pro Asp Val Arg Met Arg Leu 485 490 495 Met Ala Met Ala Val Asp Thr Gly Gly Glu Ala Gly Val Thr Asp Asn 500 505 510 Ala Tyr Arg Phe Trp Arg Arg Cys Arg Ser Asp Gly Leu Gly Asn Arg 515 520 525 Val Phe Leu Phe Lys Gly Asp Gly Leu Arg Arg Asp Arg Leu Ile Asn 530 535 540 Arg Thr Phe Pro Asp Asn Thr Gly Arg Ser Ala Arg Arg Ala Arg Ala 545 550 555 560 Ser Gly Asp Val Ala Leu Trp Leu Val Gln Thr Asp Ala Phe Lys Asp 565 570 575 Arg Val Asn Asn Ala Leu Trp Arg Asp Thr Pro Gly Pro Asn Tyr Ile 580 585 590 His Phe Pro Asp Trp Leu Gly Arg Trp Phe Tyr Asp Glu Leu Thr Tyr 595 600 605 Glu Glu Arg Gly Ser Asp Gly Lys Trp Arg Lys Pro Gly Arg Gly Ala 610 615 620 Asn Glu Ala Phe Asp Leu Leu Val Tyr Ala Asp Ala Leu Ala Val Leu 625 630 635 640 His Gly Tyr Glu Lys Ile Arg Trp Pro Ser Ala Pro Asp Trp Ala Gln 645 650 655 Arg Glu Thr Trp Leu Val Phe Pro Gln Glu Arg Ser Gly Glu Thr Val 660 665 670 Ser Pro Glu Leu Thr Ala Gly Ala Glu Lys Arg Arg Arg Arg Lys Lys 675 680 685 Lys Leu Arg Thr Glu Arg Ala Glu Asp Asn Pro Trp Ile Thr Ser Gly 690 695 700 Gly Trp Leu * 705 <210> 580 <211> 159 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22282..22758) <400> 580 Met Asp Gly Glu Leu Lys Asn Met Lys Leu Asn Ile Asn Gln Leu Ala 1 5 10 15 Ala Leu Ser Gly Leu His Arg Gln Thr Val Ala Ala Arg Met Ala Asp 20 25 30 Val Pro Leu Ala Pro Gly Ser Asn Glu Lys Lys Lys Leu Tyr Leu Leu 35 40 45 Thr Asp Leu Ile Thr Ser Leu Leu Glu Lys Pro Pro Ser Ser Glu Asp 50 55 60 Glu Asp Met Asp Pro His Ala Arg Lys Ala Trp Tyr Gln Ser Glu Arg 65 70 75 80 Glu Arg Leu Lys Phe Gln His Glu Thr Val Gln Leu Val Pro Val Ser 85 90 95 Asp Val Arg Arg Ser Phe Ser Val Val Val Lys Ala Ile Val Gln Val 100 105 110 Leu Glu Thr Trp Pro Asp Arg Leu Glu Arg Asp Arg Gly Trp Thr Ala 115 120 125 Ser Gln Leu Asn Glu Val Gln Ile Val Val Asp Glu Ile Arg Asp Thr 130 135 140 Leu Glu Lys Ala Val Ile Asp Cys Cys Asp Glu Ala Asp Met * 145 150 155 <210> 581 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23275..23460) <400> 581 Met Arg Glu Leu Lys Met Lys Leu Cys Val Leu Met Leu Pro Leu Val 1 5 10 15 Val Ser Ala Cys Gly Ser Thr Pro Pro Ala Pro Val Pro Cys Val Lys 20 25 30 Pro Pro Ala Pro Pro Ala Trp Ile Met Gln Pro Ala Pro Asp Trp Gln 35 40 45 Thr Pro Leu Asn Gly Ile Ile Ser Ser Ser Glu Asn Gly * 50 55 60 <210> 582 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23213..23680) <400> 582 Met Asn Arg Val Leu Cys Val Val Ile Ile Val Leu Ala Val Gly Tyr 1 5 10 15 Gly Ala Leu Trp Leu Ala Thr Asn His Tyr Arg Asp Asn Ala Leu Thr 20 25 30 Tyr Lys Ala Gln Arg Asp Lys Lys Ala Arg Glu Leu Glu Gln Ala Asn 35 40 45 Ala Thr Ile Thr Asp Met Gln Val Arg Gln Arg Asp Val Ala Ala Leu 50 55 60 Asp Ala Lys Tyr Ser Arg Glu Leu Ala Asp Ala Arg Ala Glu Asn Glu 65 70 75 80 Thr Leu Arg Ala Asp Val Ala Ala Gly Arg Lys Arg Leu Arg Ile Asn 85 90 95 Ala Thr Cys Ser Gly Thr Val Arg Glu Ala Thr Gly Thr Ser Gly Val 100 105 110 Asp Asn Ala Thr Gly Pro Arg Leu Ala Asp Thr Ala Glu Arg Asp Tyr 115 120 125 Phe Ile Leu Arg Glu Arg Leu Met Thr Met Gln Lys Gln Leu Glu Gly 130 135 140 Ala Gln Asp Tyr Ile Arg Thr Gln Cys Leu Asn * 145 150 155 <210> 583 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23834..24403) <400> 583 Met Asn Met Met Ala Val Pro Phe His Gly Asn Ser Leu Tyr Val Val 1 5 10 15 Asn His Asn Gly Glu Pro Tyr Val Pro Met Lys Pro Val Val Ala Gly 20 25 30 Met Gly Leu Ala Trp Gln Ser Gln Leu Ala Lys Leu Arg Gln Arg Phe 35 40 45 Ala Ser Thr Ile Thr Glu Ile Val Met Val Ala Glu Asp Gly Lys Gln 50 55 60 Arg Asn Met Val Ser Met Pro Leu Arg Lys Leu Ala Gly Trp Leu Gln 65 70 75 80 Thr Ile Asn Pro Asn Lys Val Lys Pro Glu Ile Arg Asp Lys Val Ile 85 90 95 Arg Tyr Gln Glu Glu Cys Asp Asp Val Leu Tyr Glu Tyr Trp Thr Lys 100 105 110 Gly Phe Val Val Asn Pro Arg Lys Met Ser Val Met Glu Glu Leu Asn 115 120 125 Gln Ala Cys Ala Asp Met Lys Arg Asp Lys Asn Ile Ala Ser Val Phe 130 135 140 Ala Thr Gly Leu Asn Glu Trp Lys Gln Val Lys Ala Ala His Val Ser 145 150 155 160 Lys Ile Arg Thr Leu Val Asn Glu Ala Asn Met Leu Ile Asp Phe Val 165 170 175 Leu Ala Asp Thr Gly Lys Gly Lys Ile Thr Lys Ala Asp * 180 185 <210> 584 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24674..25207) <400> 584 Met Ser Arg Lys Leu Arg Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Ala Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Thr Arg Val Asp Gly Lys Pro Val Ile 50 55 60 Pro Gly Met Lys Leu Ser Lys Glu Lys Cys Asp Arg Val Asn Ala Ile 65 70 75 80 Glu Arg Asp Lys Ala Leu Ala Trp Val Glu Lys Asn Ile Lys Val Pro 85 90 95 Leu Thr Glu Pro Gln Lys Ala Gly Ile Ala Ser Phe Cys Pro Tyr Asn 100 105 110 Ile Gly Pro Gly Lys Cys Phe Pro Ser Thr Phe Tyr Arg Arg Ile Asn 115 120 125 Ala Gly Asp Arg Lys Gly Ala Cys Glu Ala Ile Arg Trp Trp Ile Lys 130 135 140 Asp Gly Gly Arg Asp Cys Arg Ile Arg Ser Asn Asn Cys Tyr Gly Gln 145 150 155 160 Val Ser Arg Arg Asp Gln Glu Ser Ala Leu Ala Cys Trp Gly Ile Asp 165 170 175 Arg * <210> 585 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25212..25427) <400> 585 Met Tyr Gln Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser 1 5 10 15 Ala Val Gly Thr Gly Tyr Trp Phe Leu Gln Leu Leu Asp Arg Val Ser 20 25 30 Pro Ser Gln Trp Ala Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly 35 40 45 Leu Leu Thr Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Lys Glu Asp Arg 50 55 60 Arg Lys Ala Ala Arg Gly Glu * 65 70 <210> 586 <211> 82 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25505..25750) <400> 586 Met Ser Glu Ile Thr Ser Leu Val Thr Ala Glu Ala Val Lys Glu Val 1 5 10 15 Leu Arg Ser Glu Glu Val Arg Ser Ala Leu Lys Gln Lys Leu Arg His 20 25 30 Asn Leu Glu Ala Arg Leu Asp Ala Glu Val Asp Ala Ile Leu Asp Glu 35 40 45 Leu Leu Gly Ala Pro Ala Ala Pro Glu Pro Glu Gly Ile Ala Gly Glu 50 55 60 Gly Ser Ala Ser Asp Ser Gly Asp Pro Thr Pro Asp Ser Asp Met Met 65 70 75 80 Met * <210> 587 <211> 60 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25791..25970) <400> 587 Met Thr Phe Leu Asn Gln Leu Met Leu Tyr Phe Cys Thr Val Val Cys 1 5 10 15 Val Leu Tyr Leu Leu Ser Gly Gly Tyr Arg Ala Met Arg Asp Phe Trp 20 25 30 Arg Arg Gln Ile Asp Lys Arg Ala Ala Glu Lys Ile Ser Ala Ser Gln 35 40 45 Ser Ala Gly Ser Lys Pro Glu Glu Pro Leu Ile * 50 55 <210> 588 <211> 649 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26108..28054) <400> 588 Met Ala Phe Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Asp Ala Leu Ala Gln Lys Ile Arg Glu Gly Trp Gln Pro Tyr 20 25 30 Gly Gly Pro Phe Ser Ser Tyr Thr Asp Asp Gly Ala Ala Leu Ile Gln 35 40 45 Ala Ile Val Ala Glu Gly Asp Val Ser Thr Pro Val Val Val Lys Leu 50 55 60 Thr Gly Gly Glu Gly Ala Val Ile Ser Ala Thr Ser Asp Pro Gly Tyr 65 70 75 80 Tyr Phe Val Val Val Leu Ala Gly Gln Ser Asn Gly Met Ser Tyr Gly 85 90 95 Glu Gly Leu Pro Leu Pro Glu Thr Tyr Asp Arg Pro Asp Pro Arg Ile 100 105 110 Lys Gln Leu Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Val Ala Cys 115 120 125 Lys Tyr Asn Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln 130 135 140 Asp Met Ser Arg Leu Asn His Pro Lys Ala Asp Leu Ser Lys Gly Gln 145 150 155 160 Tyr Gly Thr Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro 165 170 175 Phe Ile Pro Ala Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly 180 185 190 Gly Ser Ala Phe Thr Thr Gly Ala Asp Gly Thr Tyr Ser Asp Ala Ser 195 200 205 Gly Ala Ser Glu Asn Ser Thr Arg Trp Gly Val Asp Lys Pro Leu Tyr 210 215 220 Lys Asp Leu Ile Gly Arg Thr Lys Ala Ala Leu Lys Lys Asn Pro Lys 225 230 235 240 Asn Val Leu Phe Ala Val Val Trp Met Gln Gly Glu Phe Asp Phe Gly 245 250 255 Gly Thr Pro Ala Asn His Ala Ala Gln Phe Gly Ala Leu Val Asp Lys 260 265 270 Phe Arg Ala Asp Leu Ala Asp Met Ala Gly Gln Cys Val Gly Gly Ser 275 280 285 Ala Asp Gly Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Phe Trp Lys 290 295 300 Gln Lys Asn Glu Ser Ser Tyr Gln Thr Val Tyr Gly Ser Tyr Lys Asn 305 310 315 320 Lys Thr Glu Lys Asn Ile His Phe Val Pro Phe Met Thr Asp Glu Asn 325 330 335 Gly Val Asn Val Pro Thr Asn Lys Pro Glu Glu Asp Pro Asp Ile Pro 340 345 350 Gly Ile Gly Tyr Tyr Gly Ser Lys Trp Arg Asp Ser Ser Ala Thr Trp 355 360 365 Thr Ser Gln Asp Arg Ala Ser His Phe Ser Ala Trp Ala Arg Arg Gly 370 375 380 Ile Ile Ser Asp Arg Leu Ala Thr Ala Ile Leu Arg His Ala Gly Arg 385 390 395 400 Val Ala Leu Asn Ala Gly Ala Ser Ser Thr Val Ser Glu Val Arg Pro 405 410 415 Ser Ser Pro Ser Gly Ala Glu Ala Thr Gly Val Thr Thr Leu Leu Ser 420 425 430 Tyr Leu Ala Ser Glu Ser Glu Gly Ser Leu Lys Val Gln Gly Trp Ser 435 440 445 Ala Ser Gly Gly Arg Ala Glu Val Val Ser Asp Ala Glu Gly Thr Gly 450 455 460 Gly Lys Ala Val Lys Leu Thr Lys Glu Ala Gly Lys Ser Ser Trp Val 465 470 475 480 Leu Glu Tyr Ala Ala Gly Asn Gly Ala Ala Leu Leu Gln Lys Gly Gly 485 490 495 Gln Ile Arg Cys Arg Phe Lys Val Ser Gly Val Leu Ala Ala Asn Gln 500 505 510 Tyr Val Met Ala Phe Tyr Trp Pro Val Ser Ser Leu Pro Gln Gly Val 515 520 525 Ala Leu Thr Gly Asp Gly Gly Asn Asn Leu Leu Ala Ala Phe Tyr Ile 530 535 540 Gln Thr Asp Ala Lys Asp Leu Asn Val Met Tyr His Asn Ala Lys Val 545 550 555 560 Ala Thr Asn Asn Leu Lys Leu Gly Thr Phe Gly Ala Phe Asp Asn Glu 565 570 575 Trp His Thr Leu Ala Phe Arg Phe Ala Gly Asn Asn Ser Leu Gln Val 580 585 590 Thr Pro Val Ile Asp Gly Gln Asp Gly Thr Pro Phe Thr Leu Thr Gln 595 600 605 Ser Pro Val Ser Ala Phe Ala Ala Asp Lys Leu His Val Thr Asp Ile 610 615 620 Thr Lys Gly Ala Thr Tyr Pro Val Leu Ile Asp Ser Ile Ala Val Glu 625 630 635 640 Val Asn Asn Thr Asp Thr Ala Ala * 645 <210> 589 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28565..28834) <400> 589 Met Lys Lys Thr Leu Leu Ile Ala Ala Ser Leu Ser Phe Phe Ser Ala 1 5 10 15 Ser Ala Leu Ala Thr Pro Asp Cys Val Thr Gly Lys Val Glu Tyr Thr 20 25 30 Lys Tyr Asn Asp Asp Asp Thr Phe Thr Val Lys Val Gly Asp Lys Glu 35 40 45 Leu Phe Thr Asn Arg Trp Asn Leu Gln Ser Leu Leu Leu Ser Ala Gln 50 55 60 Ile Thr Gly Met Thr Val Thr Ile Lys Thr Asn Ala Cys His Asn Gly 65 70 75 80 Gly Gly Phe Ser Glu Val Ile Phe Arg * 85 <210> 590 <211> 316 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28844..29791) <400> 590 Met Lys Ile Ile Ile Phe Arg Val Leu Thr Phe Phe Phe Val Ile Phe 1 5 10 15 Ser Val Asn Val Val Ala Lys Glu Phe Thr Leu Asp Phe Ser Thr Ala 20 25 30 Lys Thr Tyr Val Asp Ser Leu Asn Val Ile Arg Ser Ala Ile Gly Thr 35 40 45 Pro Leu Gln Thr Ile Ser Ser Gly Gly Thr Ser Leu Leu Met Ile Asp 50 55 60 Ser Gly Thr Gly Asp Asn Leu Phe Ala Val Asp Val Arg Gly Ile Asp 65 70 75 80 Pro Glu Glu Gly Arg Phe Asn Asn Leu Arg Leu Ile Val Glu Arg Asn 85 90 95 Asn Leu Tyr Val Thr Gly Phe Val Asn Arg Thr Asn Asn Val Phe Tyr 100 105 110 Arg Phe Ala Asp Phe Ser His Val Thr Phe Pro Gly Thr Thr Ala Val 115 120 125 Thr Leu Ser Gly Asp Ser Ser Tyr Thr Thr Leu Gln Arg Val Ala Gly 130 135 140 Ile Ser Arg Thr Gly Met Gln Ile Asn Arg His Ser Leu Thr Thr Ser 145 150 155 160 Tyr Leu Asp Leu Met Ser His Ser Gly Thr Ser Leu Thr Gln Ser Val 165 170 175 Ala Arg Ala Met Leu Arg Phe Val Thr Val Thr Ala Glu Ala Leu Arg 180 185 190 Phe Arg Gln Ile Gln Arg Gly Phe Arg Thr Thr Leu Asp Asp Leu Ser 195 200 205 Gly Arg Ser Tyr Val Met Thr Ala Glu Asp Val Asp Leu Thr Leu Asn 210 215 220 Trp Gly Arg Leu Ser Ser Val Leu Pro Asp Tyr His Gly Gln Asp Ser 225 230 235 240 Val Arg Val Gly Arg Ile Ser Phe Gly Ser Ile Asn Ala Ile Leu Gly 245 250 255 Ser Val Ala Leu Ile Leu Asn Cys His His His Ala Ser Arg Val Ala 260 265 270 Arg Met Ala Ser Asp Glu Phe Pro Ser Met Cys Pro Ala Asp Gly Arg 275 280 285 Val Arg Gly Ile Thr His Asn Lys Ile Leu Trp Asp Ser Ser Thr Leu 290 295 300 Gly Ala Ile Leu Met Arg Arg Thr Ile Ser Ser * 305 310 315 <210> 591 <211> 145 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30298..30732) <400> 591 Met Arg Asp Ile Arg Gln Val Leu Glu Cys Trp Gly Ala Trp Ala Ala 1 5 10 15 Asn Asn His Glu Asp Val Thr Trp Ser Pro Ile Ala Ala Gly Phe Lys 20 25 30 Gly Leu Ile Pro Glu Lys Val Lys Ser Arg Pro Gln Cys Cys Asp Asp 35 40 45 Asp Ala Met Val Ile Cys Gly Cys Ile Ala Arg Leu Tyr Arg Asn Asn 50 55 60 Arg Asp Leu His Asp Leu Leu Val Asp Tyr Tyr Val Leu Gly Gly Thr 65 70 75 80 Phe Met Ala Leu Ala Arg Lys His Gly Cys Ser Asp Thr Cys Ile Gly 85 90 95 Lys Arg Leu His Lys Ala Glu Gly Ile Val Glu Gly Met Leu Met Met 100 105 110 Leu Gly Val Arg Leu Glu Met Asp Arg Tyr Val Glu Arg Glu Leu Pro 115 120 125 Gly Gly Arg Thr Ser Val Phe Tyr Gln Arg Lys Asn Ser Leu Arg Ser 130 135 140 * <210> 592 <211> 65 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30725..30919) <400> 592 Met Thr Phe Thr Val Lys Thr Ile Pro Asp Met Leu Val Glu Ala Tyr 1 5 10 15 Glu Asn Gln Thr Glu Val Ala Arg Ile Leu Asn Cys Ser Arg Asn Thr 20 25 30 Val Arg Lys Tyr Thr Gly Asp Lys Glu Gly Lys Arg His Ala Ile Val 35 40 45 Asn Gly Val Leu Met Val His Arg Gly Trp Gly Lys Asp Thr Asp Ala 50 55 60 * <210> 593 <211> 202 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30916..31521) <400> 593 Met Ala Lys Pro Ala Arg Arg Lys Cys Lys Ile Cys Lys Glu Trp Phe 1 5 10 15 His Pro Ala Phe Ser Asn Gln Trp Trp Cys Cys Pro Glu His Gly Thr 20 25 30 Gln Leu Ala Leu Lys Leu Gln Ser Lys Gln Arg Lys Lys Ala Glu Lys 35 40 45 Ala Ala Glu Lys Lys Arg Arg Arg Glu Glu Gln Lys Gln Lys Asp Lys 50 55 60 Leu Lys Ile Arg Lys Leu Ala Leu Lys Pro Arg Ser Tyr Trp Ile Lys 65 70 75 80 Gln Ala Gln Gln Ala Val Asn Ala Phe Ile Arg Glu Arg Asp Arg Asp 85 90 95 Leu Pro Cys Ile Ser Cys Gly Thr Leu Met Ser Ala Gln Trp Asp Ala 100 105 110 Gly His Tyr Arg Thr Thr Ala Ala Ala Pro Gln Leu Arg Phe Asp Glu 115 120 125 Arg Asn Ile His Lys Gln Cys Val Val Cys Asn Gln His Lys Ser Gly 130 135 140 Asn Leu Val Pro Tyr Arg Val Glu Leu Ile Asn Arg Ile Gly Gln Glu 145 150 155 160 Ala Val Asp Glu Ile Glu Ser Asn His Asn Arg His Arg Trp Thr Ile 165 170 175 Glu Glu Cys Arg Ala Ile Lys Ala Lys Tyr Gln Gln Lys Leu Lys Asp 180 185 190 Leu Arg Asn Ser Arg Ser Glu Ala Ala * 195 200 <210> 594 <211> 70 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31514..31723) <400> 594 Met Leu Thr Ser Asp Phe Leu Met Val Lys Ala Met Leu Ser Pro Ser 1 5 10 15 Gln Ser Leu Gln Tyr Gln Lys Glu Ser Val Glu Arg Ala Leu Thr Cys 20 25 30 Ala Asn Cys Gly Gln Lys Leu His Val Leu Glu Val His Val Cys Glu 35 40 45 His Cys Cys Ala Glu Leu Met Ser Asp Pro Asn Ser Ser Met Tyr Glu 50 55 60 Glu Glu Asp Asp Gly * 65 <210> 595 <211> 134 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31683..32084) <400> 595 Met Leu Leu Ile Gln Pro Gly Phe Gly Leu Ser Ile Lys Lys Gly His 1 5 10 15 Met Phe Gly Glu Lys Glu Ser Gln Arg Lys Met Val Ser Ile Arg Leu 20 25 30 Pro Phe Ile Ser Ile Tyr Trp Leu Asn Arg Glu Ala Thr Asn Tyr Trp 35 40 45 Tyr Thr Cys Ala Arg Ala Ala Phe Asn Asp Pro Asp Trp Phe Val Lys 50 55 60 Asn His His Ala Val Arg Gln Ala Lys Arg Lys Ala Asn Met Thr Tyr 65 70 75 80 Met Lys Ala Tyr Gln Lys Ala Trp Lys Glu His Arg Asp Arg Tyr Gln 85 90 95 Gln Asp Met Glu Lys Leu Glu Ser Glu Asn Met Glu Leu Arg Arg Lys 100 105 110 Leu Gly Glu Ala Lys Arg Asp Ile Asp Ala Tyr Lys Arg Leu Phe Asn 115 120 125 Gly Glu Ser His Ala * 130 <210> 596 <211> 59 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32087..32263) <400> 596 Met Arg Arg Gln Arg Arg Ser Ile Thr Asp Ile Ile Cys Glu Asn Cys 1 5 10 15 Lys Tyr Leu Pro Thr Lys Arg Ser Arg Asn Lys Arg Lys Pro Ile Pro 20 25 30 Lys Glu Ser Asp Val Lys Thr Phe Asn Tyr Thr Ala His Leu Trp Asp 35 40 45 Ile Arg Trp Leu Arg His Arg Ala Arg Lys * 50 55 <210> 597 <211> 176 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32260..32787) <400> 597 Met Thr Ile Lys Ser Asn Thr Pro Ala His Asp Lys Asp Cys Trp Gln 1 5 10 15 Thr Pro Leu Trp Leu Phe Asp Ala Leu Asp Ile Glu Phe Gly Phe Trp 20 25 30 Leu Asp Ser Ala Ala Ser Asp Lys Asn Ala Leu Cys Ala His Trp Leu 35 40 45 Thr Glu Ala Asp Asp Ala Leu Asn Ser Glu Trp Ile Ser His Gly Ala 50 55 60 Ile Trp Asn Asn Pro Pro Tyr Ser Asn Ile Arg Pro Trp Val Glu Lys 65 70 75 80 Ala Ala Glu Gln Cys Ile Gln Gln Arg Gln Thr Val Val Met Leu Val 85 90 95 Pro Glu Asp Met Ser Val Gly Trp Phe Ser Lys Ala Leu Glu Ser Val 100 105 110 Asp Glu Val Arg Ile Ile Thr Asp Gly Arg Ile Asn Phe Ile Glu Pro 115 120 125 Ser Thr Gly Leu Glu Lys Lys Gly Asn Ser Lys Gly Ser Met Leu Leu 130 135 140 Ile Trp Arg Pro Phe Ile Ser Pro Arg Arg Met Phe Thr Thr Val Ser 145 150 155 160 Lys Ala Ala Leu Met Ala Ile Gly Leu Gly Val Arg Arg Ala Ala * 165 170 175 <210> 598 <211> 149 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32784..33230) <400> 598 Met Lys Gln Thr Phe Leu Leu Arg Asn Glu Ala Ile Arg Asn Asn Ala 1 5 10 15 Ile Asp Ala Ile Leu Ser Leu Pro Ile Asp Asp Lys Ser Pro His Glu 20 25 30 Val His Val Lys Glu Pro Arg Arg Ser Lys Ala Gln Asn Asp Arg Met 35 40 45 Trp Pro Met Leu Asn Asp Val Ser Arg Gln Val Leu Trp His Gly Gln 50 55 60 Arg Leu Ala Pro Glu Asp Trp Lys Asp Leu Phe Thr Ala Leu Trp Leu 65 70 75 80 Lys Thr Lys Lys Leu Glu Gln Arg Ser Val Pro Gly Ile Asp Gly Gly 85 90 95 Val Val Met Leu Gly Val Arg Thr Ser Lys Met Arg Lys Ala Ser Met 100 105 110 Thr Glu Leu Ile Glu Ile Met Phe Trp Phe Gly Ser Glu Arg Asn Val 115 120 125 Arg Trp Ser Asp Asp Ser Arg Arg Glu Tyr Glu Trp Ser Gln Arg Lys 130 135 140 Gly Arg Ala Ala * 145 <210> 599 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33187..33612) <400> 599 Val Lys Ser Trp Cys Val Gly Ile Gly Ile Val His Arg Pro Val Cys 1 5 10 15 Arg Leu Met Ser Cys Met Ser Ile His Leu Pro His Asp Ala Ile Arg 20 25 30 Val Thr Val Phe Phe Asp Gly Cys Ser Asn Ser Thr Met Ser Phe Ser 35 40 45 Ala Thr Glu Leu Ser Gly Val Trp Ile Leu Ser Glu Gly Val Ser Met 50 55 60 Ser Asp Leu Ser Leu Thr Gln Pro Lys Leu Lys Glu Cys Pro Phe Cys 65 70 75 80 Gly Gly Asn Ala Arg Leu Trp Val Glu Ala Gly Ile Asn Ile Asp Val 85 90 95 Trp Gly Tyr Ala Glu Cys Asp Leu Cys Glu Ala Arg Gly Ala Trp Ala 100 105 110 Pro Ser Val Ala Ala Ala Ala Glu Lys Trp Asn Arg Arg Ala Gly Asp 115 120 125 Glu Ala Asn Leu Ser Ala Ser Gln Arg Ser Asn Gln Lys * 130 135 140 <210> 600 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33782..34060) <400> 600 Val Asn Asp Ser Tyr Arg Gln Phe Glu Asn Trp Trp Ser Lys Asp Lys 1 5 10 15 Ser Gln Phe Thr Gly Asp Asp Glu Leu Lys Glu Phe Ala Trp Val Ile 20 25 30 Trp Gln Ala Ser Arg Ser Ala Ile Glu Leu Asp Ile Asp Trp Pro Glu 35 40 45 Ser Asn Asp Asp Leu Trp Lys Asp Gly Glu Glu Gly Ala Tyr Ala Met 50 55 60 Gly Tyr Glu Asp Gly Arg Asp Lys Thr Val Ile Ala Val Met Lys Ala 65 70 75 80 Ile Arg Ala Ala Gly Ile Lys Glu Lys Asn Phe Asp * 85 90 <210> 601 <211> 97 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34131..34421) <400> 601 Met Thr Gly Lys Glu Ala Ile Ile His Tyr Leu Gly Thr His Asn Ser 1 5 10 15 Phe Cys Ala Pro Asp Val Ala Ala Leu Thr Gly Ala Thr Val Thr Ser 20 25 30 Ile Asn Gln Ala Ala Ala Lys Met Ala Arg Ala Gly Leu Leu Val Ile 35 40 45 Glu Gly Lys Val Trp Arg Thr Val Tyr Tyr Arg Phe Ala Thr Arg Glu 50 55 60 Glu Arg Glu Gly Lys Val Ser Thr Asn Leu Ile Phe Lys Glu Cys Arg 65 70 75 80 Gln Ser Ala Ala Met Lys Arg Val Leu Ala Val Tyr Gly Val Lys Arg 85 90 95 * <210> 602 <211> 234 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34418..35119) <400> 602 Met Lys Asn Ile Ala Ala Gln Met Val Asn Phe Asp Arg Glu Gln Met 1 5 10 15 Arg Arg Ile Ala Asn Asn Met Pro Glu Gln Tyr Asp Glu Lys Pro Gln 20 25 30 Val Gln Gln Val Ala Gln Ile Ile Asn Gly Val Phe Ser Gln Leu Leu 35 40 45 Ala Thr Phe Pro Ala Ser Leu Ala Asn Arg Asp Gln Asn Glu Val Asn 50 55 60 Glu Ile Arg Arg Gln Trp Val Leu Ala Phe Arg Glu Asn Gly Ile Thr 65 70 75 80 Ser Met Glu Gln Val Asn Ala Gly Met Arg Val Ala Arg Arg Gln Asn 85 90 95 Arg Pro Phe Leu Pro Ser Pro Gly Gln Phe Val Ala Trp Cys Arg Glu 100 105 110 Glu Ala Ser Val Ile Ala Gly Leu Pro Asn Val Ser Glu Leu Val Asp 115 120 125 Met Val Tyr Glu Tyr Cys Arg Lys Arg Gly Leu Tyr Pro Asp Ala Glu 130 135 140 Ser Tyr Pro Trp Lys Ser Asn Ala His Tyr Trp Leu Val Thr Asn Leu 145 150 155 160 Tyr Gln Asn Met Arg Ala Asn Ala Leu Thr Asp Ala Glu Leu Arg Arg 165 170 175 Lys Ala Ala Asp Glu Leu Thr Cys Met Thr Ala Arg Ile Asn Arg Gly 180 185 190 Glu Ala Ile Pro Glu Pro Val Lys Gln Leu Pro Val Met Gly Gly Arg 195 200 205 Pro Leu Asn Arg Val Gln Ala Leu Ala Lys Ile Ala Glu Ile Lys Ala 210 215 220 Lys Phe Gly Leu Lys Gly Ala Ser Val * 225 230 <210> 603 <211> 313 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35116..36054) <400> 603 Met Thr Asn Thr Ala Lys Ile Leu Asn Phe Gly Arg Gly Asn Phe Ala 1 5 10 15 Glu Gln Glu Arg Asn Val Ala Asp Leu Asp Asp Gly Tyr Ala Arg Leu 20 25 30 Ser Asn Met Leu Ile Glu Ala Tyr Ser Gly Ala Asp Leu Thr Lys Arg 35 40 45 Gln Phe Lys Val Leu Leu Ala Ile Leu Arg Lys Thr Tyr Gly Trp Asn 50 55 60 Lys Pro Met Asp Arg Ile Thr Asp Ser Gln Leu Ser Glu Ile Thr Lys 65 70 75 80 Leu Pro Val Lys Arg Cys Asn Glu Ala Lys Leu Glu Leu Val Arg Met 85 90 95 Asn Ile Ile Lys Gln Gln Gly Gly Met Phe Gly Pro Asn Lys Asn Ile 100 105 110 Ser Glu Trp Cys Ile Pro Gln Asn Glu Gly Gly Ser Pro Lys Met Arg 115 120 125 Asp Ile Pro Gln Asn Glu Gly Lys Ser Pro Lys Thr Arg Asp Lys Thr 130 135 140 Ser Leu Lys Leu Gly Asp Cys Tyr Pro Ser Lys Gln Gly Asp Thr Lys 145 150 155 160 Asp Thr Ile Thr Lys Glu Lys Arg Lys Asp Tyr Ser Ser Glu Asn Ser 165 170 175 Gly Glu Ser Ser Asp Gln Pro Glu Asn Asp Leu Ser Val Val Lys Pro 180 185 190 Asp Ala Ala Ile Gln Ser Gly Ser Lys Trp Gly Thr Ala Glu Asp Leu 195 200 205 Thr Ala Ala Glu Trp Met Phe Asp Met Val Lys Thr Ile Ala Pro Ser 210 215 220 Ala Arg Lys Pro Asn Phe Ala Gly Trp Ala Asn Asp Ile Arg Leu Met 225 230 235 240 Arg Glu Arg Asp Gly Arg Asn His Arg Asp Met Cys Val Leu Phe Arg 245 250 255 Trp Ala Cys Gln Asp Asn Phe Trp Ser Gly Asn Val Leu Ser Pro Ala 260 265 270 Lys Leu Arg Asp Lys Trp Thr Gln Leu Glu Ile Asn Arg Asn Lys Gln 275 280 285 Gln Ala Gly Val Thr Ala Ser Lys Pro Lys Leu Asp Leu Thr Asn Thr 290 295 300 Asp Trp Ile Tyr Gly Val Asp Leu * 305 310 <210> 604 <211> 99 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36087..36383) <400> 604 Met Ala Gln Ala Ser Tyr Ser Lys Pro Thr Gln Arg Glu Ile Asp Arg 1 5 10 15 Ala Glu Thr Asp Leu Leu Ile Asn Leu Ser Thr Leu Thr Gln Arg Gly 20 25 30 Leu Ala Lys Met Ile Gly Cys His Glu Ser Lys Ile Ser Arg Thr Asp 35 40 45 Trp Arg Phe Ile Ala Ser Val Leu Cys Ala Phe Gly Met Ala Ser Asp 50 55 60 Ile Ser Pro Ile Ser Arg Ala Phe Lys Tyr Ala Leu Asp Gly Ile Thr 65 70 75 80 Lys Lys Lys Ser Pro Val Ala Ala Gly Asp Ser Lys Gln Ile Asp Met 85 90 95 Gln Phe * <210> 605 <211> 73 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36498..36716) <400> 605 Met Asn Lys Ile Ala Gln Gln Arg Lys Lys Ile Gly Val Ser Gln Ala 1 5 10 15 Val Leu Ala Ser Ala Ile Gly Trp Gly Gln Ser Arg Ile Ala Asn Tyr 20 25 30 Glu Leu Asn Ile Arg Thr Pro Gly Leu Asn Asp Cys Arg Met Ile Val 35 40 45 Glu Gly Leu Arg Lys Leu Gly Cys Gln Cys Ser Leu Asp Asp Val Phe 50 55 60 Pro Pro Ser Ser Asn Lys Ala Ala * 65 70 <210> 606 <211> 213 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36834..37472) <400> 606 Met His Glu Ile Ile Gly Glu Arg Ile Lys Ser Leu Arg Glu Ala Lys 1 5 10 15 Gly Leu Ser Gln Ala Gln Leu Ala Lys Leu Cys Gly Trp Ala Ala Pro 20 25 30 Ser Arg Leu Gly Asn Tyr Glu Leu Gly Thr Arg Lys Val Ser Ala Asp 35 40 45 Asp Ala Leu Val Leu Gly Ala Ala Leu Gly Val Ser Pro Ala Lys Ile 50 55 60 Met Phe Gly Glu Asp Ser Asp Ala Val Phe Arg Gln Tyr Glu Tyr Pro 65 70 75 80 Leu Phe Ser Ser Val Gln Ala Gly Pro Phe Ser Glu Val Gly Ser Tyr 85 90 95 Thr Ala Ser Asp Ala Lys Ala Trp Val Pro Thr Thr Thr Lys Ala Ser 100 105 110 Glu Lys Ala Phe Trp Leu Glu Val Lys Gly His Ser Met Thr Ala Pro 115 120 125 Gln Gly Val Arg Pro Ser Phe Pro Glu Gly Met Leu Ile Leu Val Asp 130 135 140 Pro Ala Glu Pro Val Glu Ser Gly Asp Phe Cys Val Ala Ser Ala Asn 145 150 155 160 Gly Asp Ser Glu Ala Thr Phe Lys Lys Tyr Glu Lys Asp Ala Gly Val 165 170 175 Ser Tyr Leu Val Pro Leu Asn Pro Ala Tyr Arg Thr Leu Asp Cys Asp 180 185 190 His Ser Cys Arg Ile Ile Gly Lys Val Val Lys Ala Gln Trp Pro Glu 195 200 205 Glu Thr Phe Gly * 210 <210> 607 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37595..37876) <400> 607 Met Ser Asp Lys Gln Glu Val Ser Leu Ala His Ile Asn Asp Val Leu 1 5 10 15 Glu Ser Lys Asn Tyr Ile Glu Thr Asn Ala Asp Gly Val Val Thr Ile 20 25 30 Gly Thr Asp Asn Asn Gly Tyr Glu Val Phe Asn Phe Val Phe Leu Asn 35 40 45 Ser Thr Pro Val Ile Gly His Met Asn Gly Glu Ile Ala Val Ala Gly 50 55 60 Met Gln Arg Thr Lys Val Ala Ser Val Thr Leu Ser Lys Gln Lys Ala 65 70 75 80 Phe Asp Phe Tyr Gln Ser Leu Lys Ser Met Phe Glu Glu * 85 90 <210> 608 <211> 184 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37883..38434) <400> 608 Met Asn Ala Ala Gln Ser Ser Leu Asp Glu Gly Lys Leu Val Ile Ala 1 5 10 15 Tyr Ser Asp Lys Asn Gly Ser Thr Val Gly Leu Glu Phe Ser Ser Val 20 25 30 Ala Ser Ser Gln Ala Thr Leu Leu Met Lys Ala Cys Ser Val Ala Ala 35 40 45 Ser Asp Lys Glu Lys Arg Ile Val Thr Ser Val Val Met Asp Asp Thr 50 55 60 Glu Ile Ile Gln Thr Thr Ser Asp Asp Gly Gly Asp Asp Met Asp Lys 65 70 75 80 Arg Leu Ala Val Leu Glu Ala Glu Val Ala His Ile Lys Ser Ser Met 85 90 95 Ala Gly Ile Lys Glu Asp Thr Arg Lys Ile Ser Ser Asp Ser Thr Asp 100 105 110 Ala Lys Arg Asp Thr Ala Val Leu Leu Gln Lys Ser Leu Asp Phe Asp 115 120 125 Ala Ser Leu Ser Lys Lys Pro Ser Val Asp Tyr Phe Glu Ala Lys Phe 130 135 140 Ser Ala Leu Glu Thr Lys Ile Ala Asp Val Lys Val Trp Met Leu Gly 145 150 155 160 Val Leu Leu Ala Ser Leu Ala Met Pro Thr Ile Phe Phe Leu Ile Asn 165 170 175 Leu Tyr Leu Lys Lys Gly Gln * 180 <210> 609 <211> 91 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38947..39219) <400> 609 Met Val Thr Ile Val Trp Lys Glu Ser Lys Gly Thr Ala Lys Ser Arg 1 5 10 15 Tyr Lys Ala Arg Arg Ala Glu Leu Ile Ala Glu Arg Arg Ser Asn Glu 20 25 30 Ala Leu Ala Arg Lys Ile Ala Leu Lys Leu Ser Gly Cys Val Arg Ala 35 40 45 Asp Lys Ala Ala Ser Leu Gly Ser Leu Arg Cys Lys Lys Ala Asp Glu 50 55 60 Cys Ser Gly Ser Ile Cys Leu Pro Asn Val Ala Ile Tyr Ala Ala Gly 65 70 75 80 Tyr Arg Lys Ser Lys Gln Leu Thr Ala Arg * 85 90 <210> 610 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38802..38957) <400> 610 Met Val Thr Met Met Val Ser Phe Lys Trp Leu Trp Arg Met Thr Arg 1 5 10 15 Arg Gly Val Tyr Leu Leu Asp Arg Cys Leu Ala Ala Ala Ile Arg Ala 20 25 30 Ile Pro Lys Thr Thr Gln Val Leu Val Ser Thr Val Arg Leu Arg Val 35 40 45 Arg Arg Cys * 50 <210> 611 <211> 194 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39236..39817) <400> 611 Met Asn Asn Ser Trp Trp Gln Glu Leu Met His Phe Phe Leu Gln Gly 1 5 10 15 Met Thr Leu Lys Gln Leu Ile His Met Leu Ile Ile Leu Ile Ile Leu 20 25 30 Ile Ile Val Met Pro Val Ser Val Lys Glu Trp Ile Asn Leu His Asn 35 40 45 Pro Glu Ile Leu Pro His Tyr Trp Met Tyr Tyr Ile Leu Leu Phe Cys 50 55 60 Val Ser Tyr Val Leu Asn Gly Val Val Asn Ser Ala Tyr His Ala Val 65 70 75 80 Thr Glu Arg Ile Glu Ile Phe Ala Ala Gln Lys Arg Lys Ser Lys Glu 85 90 95 Glu Lys Tyr Val Gln Asp Leu Phe Asp Ser Leu Thr Leu Gly Glu Arg 100 105 110 Ala Tyr Leu Ala Phe Ala Val Ala Ala Asn Asn Gln Leu Lys Thr Glu 115 120 125 Lys Gly Ser Pro Glu Ala Ile Ser Leu Leu Glu Lys Gly Leu Leu Ile 130 135 140 Arg Val Pro Ser Ala Thr Gly Tyr Pro Glu Ile Asp Arg Phe Val Ile 145 150 155 160 Pro Glu Arg Tyr Arg Asn Glu Cys Tyr Ile Arg Phe Ala Gly Lys Lys 165 170 175 Asp Ser Leu Met Asp Glu Leu Ile Ala Gln Asp Lys His Gly Lys Asn 180 185 190 Lys * <210> 612 <211> 123 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40078..40446) <400> 612 Met Ser Asn Ile Lys Lys Tyr Ile Ile Asp Tyr Asp Trp Lys Ala Ser 1 5 10 15 Ile Glu Ile Glu Ile Asp His Asp Val Met Thr Glu Glu Lys Leu His 20 25 30 Gln Ile Asn Asn Phe Trp Ser Asp Ser Glu Tyr Arg Leu Asn Lys His 35 40 45 Gly Ser Val Leu Asn Ala Val Leu Ile Met Leu Ala Gln His Ala Leu 50 55 60 Leu Ile Ala Ile Ser Ser Asp Leu Asn Ala Tyr Gly Val Val Cys Glu 65 70 75 80 Phe Asp Trp Asn Asp Gly Asn Gly Gln Glu Gly Trp Pro Ser Met Asp 85 90 95 Gly Ser Glu Gly Ile Arg Ile Thr Asp Ile Asp Thr Ser Gly Ile Phe 100 105 110 Asp Ser Asp Asp Met Thr Ile Lys Ala Ala * 115 120 <210> 613 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40519..40683) <400> 613 Met Gln Tyr Ala Ile Ala Gly Trp Pro Val Ala Gly Cys Pro Ser Glu 1 5 10 15 Ser Leu Leu Glu Arg Ile Thr Arg Lys Leu Arg Asp Gly Trp Lys Arg 20 25 30 Leu Ile Asp Ile Leu Asn Gln Pro Gly Val Pro Lys Asn Gly Ser Asn 35 40 45 Thr Tyr Gly Tyr Pro Asp * 50 <210> 614 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40526..40795) <400> 614 Met Pro Leu Gln Gly Gly Leu Leu Leu Ala Ala Leu Pro Asn Leu Tyr 1 5 10 15 Leu Asn Glu Ser Pro Val Asn Tyr Val Thr Asp Gly Asn Ala Leu Ser 20 25 30 Thr Tyr Leu Ile Ser Gln Glu Ser Gln Arg Met Asp Gln Thr Leu Met 35 40 45 Ala Ile Gln Thr Lys Phe Thr Ile Ala Thr Phe Ile Gly Asp Glu Lys 50 55 60 Met Phe Arg Glu Ala Val Asp Ala Tyr Lys Lys Trp Ile Leu Met Leu 65 70 75 80 Lys Arg Arg Ser Ser Lys Ser Ile His * 85 <210> 615 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40750..40902) <400> 615 Met Asp Ile Asn Ala Glu Thr Glu Ile Lys Gln Lys His Ser Leu Thr 1 5 10 15 Pro Phe Pro Val Phe Leu Ile Ser Leu Ala Phe Arg Gly Arg Tyr Phe 20 25 30 His Ser His Phe Gln Glu Phe Ser His Glu Arg Leu Leu His Ser Gly 35 40 45 Leu Ser * 50 <210> 616 <211> 99 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40871..41167) <400> 616 Met Asn Ala Tyr Tyr Ile Gln Asp Cys Leu Glu Ala Gln Ser Trp Ala 1 5 10 15 Arg Tyr Tyr Gln Gln Ile Ala Arg Glu Glu Lys Glu Ala Glu Leu Ala 20 25 30 Asp Asp Met Glu Lys Gly Leu Pro Gln His Leu Phe Glu Ser Leu Cys 35 40 45 Ile Asp His Leu Gln Arg His Gly Ala Ser Lys Lys Ala Ile Thr Arg 50 55 60 Ala Phe Asp Asp Asp Val Glu Phe Gln Glu Arg Met Ala Glu His Ile 65 70 75 80 Arg Tyr Met Val Glu Thr Ile Ala His His Gln Val Asp Ile Asp Ser 85 90 95 Glu Val * <210> 617 <211> 262 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41173..41958) <400> 617 Met Ser Thr Ala Leu Ala Thr Leu Ala Gly Lys Leu Ala Glu Arg Val 1 5 10 15 Gly Met Asp Ser Val Asp Pro Gln Glu Leu Ile Thr Thr Leu Arg Gln 20 25 30 Thr Ala Phe Lys Gly Asp Ala Ser Asp Ala Gln Phe Ile Ala Leu Leu 35 40 45 Ile Val Ala Asn Gln Tyr Gly Leu Asn Pro Trp Thr Lys Glu Ile Tyr 50 55 60 Ala Phe Pro Asp Lys Gln Asn Gly Ile Val Pro Val Val Gly Val Asp 65 70 75 80 Gly Trp Ser Arg Ile Ile Asn Glu Asn Gln Gln Phe Asp Gly Met Asp 85 90 95 Phe Glu Gln Asp Asn Glu Ser Cys Thr Cys Arg Ile Tyr Arg Lys Asp 100 105 110 Arg Asn His Pro Ile Cys Val Thr Glu Trp Met Asp Glu Cys Arg Arg 115 120 125 Glu Pro Phe Lys Thr Arg Glu Gly Arg Glu Ile Thr Gly Pro Trp Gln 130 135 140 Ser His Pro Lys Arg Met Leu Arg His Lys Ala Met Ile Gln Cys Ala 145 150 155 160 Arg Leu Ala Phe Gly Phe Ala Gly Ile Tyr Asp Lys Asp Glu Ala Glu 165 170 175 Arg Ile Val Glu Asn Thr Ala Tyr Thr Ala Glu Arg Gln Pro Glu Arg 180 185 190 Asp Ile Thr Pro Val Asn Asp Glu Thr Met Gln Glu Ile Asn Thr Leu 195 200 205 Leu Ile Ala Leu Asp Lys Thr Trp Asp Asp Asp Leu Leu Pro Leu Cys 210 215 220 Ser Gln Ile Phe Arg Arg Asp Ile Arg Ala Ser Ser Glu Leu Thr Gln 225 230 235 240 Ala Glu Ala Val Lys Ala Leu Gly Phe Leu Lys Gln Lys Ala Thr Glu 245 250 255 Gln Lys Val Ala Ala * 260 <210> 618 <211> 226 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41955..42632) <400> 618 Met Thr Pro Asp Ile Ile Leu Gln Arg Thr Gly Ile Asp Val Arg Ala 1 5 10 15 Val Glu Gln Gly Asp Asp Ala Trp His Lys Leu Arg Leu Gly Val Ile 20 25 30 Thr Ala Ser Glu Ile His Asn Val Ile Ala Lys Pro Arg Ser Gly Lys 35 40 45 Lys Trp Pro Asp Met Lys Met Ser Tyr Phe His Thr Leu Leu Ala Glu 50 55 60 Val Cys Thr Gly Val Ala Pro Glu Val Asn Ala Lys Ala Leu Ala Trp 65 70 75 80 Gly Lys Gln Tyr Glu Asn Asp Ala Arg Thr Leu Phe Glu Phe Thr Ser 85 90 95 Gly Val Asn Val Thr Glu Ser Pro Ile Ile Tyr Arg Asp Glu Ser Met 100 105 110 Arg Thr Ala Cys Ser Pro Asp Gly Leu Cys Ser Asp Gly Asn Gly Leu 115 120 125 Glu Leu Lys Cys Pro Phe Thr Ser Arg Asp Phe Met Lys Phe Arg Leu 130 135 140 Gly Gly Phe Glu Ala Ile Lys Ser Ala Tyr Met Ala Gln Val Gln Tyr 145 150 155 160 Ser Met Trp Val Thr Arg Lys Asp Ala Trp Tyr Phe Ala Asn Tyr Asp 165 170 175 Pro Arg Met Lys Arg Glu Gly Leu His Tyr Val Val Ile Glu Arg Asn 180 185 190 Glu Lys Tyr Met Ala Ser Phe Asp Glu Met Val Pro Glu Phe Ile Glu 195 200 205 Lys Met Asp Glu Ala Leu Ala Glu Ile Gly Phe Val Tyr Gly Glu Gln 210 215 220 Trp * 225 <210> 619 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42626..42814) <400> 619 Met Val Met Lys His Pro His Asp Asn Ile Arg Val Gly Thr Ile Thr 1 5 10 15 Phe Val Tyr Ser Val Thr Lys Arg Gly Trp Val Phe Pro Gly Leu Ser 20 25 30 Val Ile Arg Asn Pro Leu Lys Ala Gln Arg Leu Ala Glu Glu Ile Asn 35 40 45 Asn Lys Arg Gly Ala Val Cys Thr Lys His Leu Leu Leu Asn * 50 55 60 <210> 620 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42787..42978) <400> 620 Met His Lys Ala Ser Pro Val Glu Leu Arg Thr Ser Ile Gly Met Ala 1 5 10 15 His Ser Leu Ala Gln Ile Gly Val Arg Phe Val Pro Ile Pro Val Glu 20 25 30 Thr Asp Glu Glu Phe His Thr Leu Ala Thr Ser Leu Ser Gln Lys Leu 35 40 45 Glu Met Met Ala Ala Lys Ala Glu Ala Asn Glu Arg Asp Pro Ala * 50 55 60 <210> 621 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42989..43270) <400> 621 Met His Phe Ser Gly Ser Arg Leu His Ile Leu Cys Ala Tyr Ala Cys 1 5 10 15 Arg His Gly Thr Cys Ser Met Thr Pro Gln Gln Glu Asn Ala Leu Arg 20 25 30 Ser Ile Ala Arg Gln Ala Asn Ser Glu Ile Lys Lys Ala Arg Gln Gln 35 40 45 Phe Pro Asp Lys Asn Val Asp Asp Ile Cys Arg Ser Val Leu Lys Lys 50 55 60 His Arg Glu Thr Val Thr Leu Met Gly Phe Thr Pro Thr His Leu Ser 65 70 75 80 Leu Ala Ile Gly Met Leu Asn Gly Val Phe Lys Glu Arg * 85 90 <210> 622 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43369..43590) <400> 622 Met Ala Asp Ile Ile Asp Ser Ala Ser Glu Ile Glu Glu Leu Gln Arg 1 5 10 15 Asn Thr Ala Ile Lys Met Arg Arg Leu Asn Tyr Gln Thr Val Ser Ala 20 25 30 Thr His Cys Cys Glu Cys Gly Asp Pro Ile Asp Glu Arg Arg Arg Leu 35 40 45 Ala Val Gln Gly Cys Arg Thr Cys Ala Ser Cys Gln Glu Asp Leu Glu 50 55 60 Leu Ile Ser Lys Gln Arg Gly Ser Lys * 65 70 <210> 623 <211> 316 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43587..44534) <400> 623 Val Ser Glu Ile Asn Tyr Gln Ala Leu Arg Glu Lys Ala Glu Lys Ala 1 5 10 15 Thr Lys Gly Ser Tyr Ile Val Gly His Thr Ser Val Asn Gln His Gly 20 25 30 Asn Leu Thr Gly Val Phe Val Cys Gln Lys Trp Lys Gly Glu Pro Gly 35 40 45 Gly Val Ile Ala Glu Cys His Val Asn Cys Leu Val Glu Thr Asp Val 50 55 60 Gln Ala Tyr Ala Asn Ala Glu Phe Ile Ala Ala Phe Asn Pro Asn Val 65 70 75 80 Ala Leu Ala Leu Leu Asp Glu Arg Glu Arg Asn Gln Gln Tyr Ile Lys 85 90 95 Arg Arg Asp Gln Glu Asn Glu Glu Ile Ala Leu Thr Val Gly Lys Leu 100 105 110 Arg Val Glu Leu Glu Ala Ala Lys Ser Lys Leu Asn Glu Gln Arg Glu 115 120 125 Tyr Tyr Glu Gly Val Ile Ala Asp Gly Ser Lys Arg Ile Ala Glu Leu 130 135 140 Glu Lys Gln Cys Ala Glu Trp Glu Arg Lys Ala Leu Ser Asn Phe Glu 145 150 155 160 Glu Cys Ala Ala Met Ala Glu Arg Ile Glu Glu Met Gln Thr Lys Ser 165 170 175 Ala Pro Asp Ser Phe Gly Ile Ile Gly Glu Asn Ile Arg Thr Gln Asp 180 185 190 Asn Arg Ile Thr Ser Asp Pro Met Phe Cys Val Tyr Gln Lys Arg Glu 195 200 205 Ile Ala Val Asp Ala Asp Tyr Asp His Asp Arg Ile Val Trp Val Asp 210 215 220 Glu Asp Gly Asn Glu Ala Asn Lys Arg His Ser Arg Arg Leu Glu Leu 225 230 235 240 Leu His Glu Asn Phe Arg Glu Pro Pro Glu Lys Trp Arg Arg Val Ala 245 250 255 Val Lys Asp Ile Asp Glu Phe Val Thr Cys Cys Phe Thr Glu Gln Gly 260 265 270 Cys Lys Asp Tyr Leu Ala Val Asn Gly His Asn Leu Arg Leu Pro Phe 275 280 285 Ile Tyr Val Lys Ser Gly Phe Arg Asn Ala Glu Tyr Ile Gly Ile Arg 290 295 300 Asn Trp Leu Ala Gly Ile Arg Ile Lys Gly Glu * 305 310 315 <210> 624 <211> 59 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44536..44712) <400> 624 Met Ala Leu Thr His Arg Glu Leu Cys Gln Ile Ala Tyr Lys Phe Leu 1 5 10 15 Lys Arg Asn Gly Phe Lys Val Cys Phe His Asp Arg Phe Ile Ala Val 20 25 30 Thr Ser Thr Gly Glu Gln Pro Asp Ala Met Gly Phe Arg Asn Ser Ala 35 40 45 Ser Cys Leu Thr Gly Glu Met Phe Ser Cys * 50 55 <210> 625 <211> 119 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45046..45402) <400> 625 Met Thr Thr Ile Thr Asp Lys Glu Leu Ile Lys Glu Ile Lys Glu Arg 1 5 10 15 Ile Gly Ser Leu Asp Val Arg Asp Asn Ile Glu Arg Arg Ala Tyr Glu 20 25 30 Ile Ala Leu Ala Ser Leu Glu Ala Glu Pro Ile Ala Trp Glu Cys Gly 35 40 45 Glu Asn Ile Ile Leu Phe Asn Pro Asp Thr Val Glu Ala Tyr Ala Lys 50 55 60 Arg Ala Glu Ile Ser Pro Lys Pro Leu Phe Ser Ala Pro Pro Ala Leu 65 70 75 80 Val Val Pro Asp Lys Leu Pro Arg Glu Tyr Arg Asn Gly Trp Pro Leu 85 90 95 Ala Tyr Ser Asp Tyr Ala Glu Gly Trp Asn Asp Cys Arg Glu Ala Met 100 105 110 Leu Gln Gly Asp Lys Ser * 115 <210> 626 <211> 121 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45399..45761) <400> 626 Met Ile Asn Arg Ile Lys Leu Glu His Ile Leu Glu Tyr Ala Arg Gln 1 5 10 15 Gln Arg His Ile Gly Gln His Cys Lys Ile Pro Pro Gly Asp Met Val 20 25 30 Glu Ile Met Glu Ile Ala Met Arg Lys Ala Gly Asn Ser Pro Val Thr 35 40 45 Pro Asp Gly Trp Ile Ser Cys Ser Glu Arg Met Pro Asn Asp Lys Gln 50 55 60 Tyr Val Trp Cys Trp Gly Lys Ser Tyr Gly Trp Thr Glu Cys Asp Thr 65 70 75 80 Phe Glu Gly Tyr Tyr Asp Cys Ser Arg Asn Lys Trp Trp Ala Val Thr 85 90 95 Asp Asn Gly Glu Glu Pro Ala Ser Lys Val Thr His Trp Met Pro Leu 100 105 110 Pro Glu Pro Pro Gln Glu Val Lys * 115 120 <210> 627 <211> 81 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45849..46091) <400> 627 Met Phe Ala Leu Ile Gln Arg Gly Gln Ile Tyr Thr Asp Arg Ala Gly 1 5 10 15 Tyr Pro Val Val Ile Thr Arg Ser Thr Gln His Ser Val Phe Phe Arg 20 25 30 Arg Met Asp Gly Arg Ser Gly Arg Val Arg Ile Gly Glu Phe Asn Asn 35 40 45 Leu Phe Glu His Ile Asp Gln Gln Glu Tyr Arg Lys Ile Leu Ala Gly 50 55 60 Thr Glu Gln Glu Met Arg Leu Lys Lys Leu Arg Ala Met Gln Arg Arg 65 70 75 80 * <210> 628 <211> 85 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46248..46502) <400> 628 Met Gln Thr Ile Ile Tyr Gln Ile Thr Pro Ser Lys Trp Cys Thr Glu 1 5 10 15 Arg Val Leu Ile Ala Ser Thr Gly Leu Lys Pro Gly Thr Ile Glu Arg 20 25 30 Ala Arg Arg Lys Ser Trp Met Gln Gly Lys Glu Tyr Arg His Tyr Ala 35 40 45 Val Glu Gly Asp Pro Gly His Tyr Ser Glu Cys Leu Tyr Asn Ile Glu 50 55 60 Glu Ile Met Arg Trp Ile Glu Asn Gln Lys Gln Pro Gly Ala Lys Asn 65 70 75 80 Ala Ser Ser Gly * <210> 629 <211> 429 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46536..47822) <400> 629 Met Ser Asn Ala Ser Tyr Pro Thr Gly Val Glu Asn His Gly Gly Ser 1 5 10 15 Leu Arg Ile Trp Phe His Tyr Asn Gly Lys Arg Val Arg Glu Asn Leu 20 25 30 Gly Val Pro Asp Thr Ala Lys Asn Arg Lys Ile Ala Gly Glu Leu Arg 35 40 45 Thr Ser Val Cys Phe Ala Ile Arg Met Gly Ser Phe Asp Tyr Ala Ala 50 55 60 Gln Phe Pro Asn Ser Pro Asn Leu Lys His Phe Gly Leu Gly Lys Arg 65 70 75 80 Glu Ile Thr Val Lys Ala Leu Ser Glu Lys Trp Leu Asp Leu Lys Lys 85 90 95 Ile Glu Ile Cys Ala Asn Ala Leu Asn Arg Tyr Gln Ser Val Ile Lys 100 105 110 Asn Met Leu Pro Met Leu Gly Glu Lys Lys Leu Val Ser Ser Ile Thr 115 120 125 Lys Glu Asp Leu Leu Phe Val Arg Arg Asp Leu Leu Thr Gly Tyr Gln 130 135 140 Lys Leu Ser Asn Gly Lys Thr Ser Ser Ile Lys Gly Arg Ser Val Val 145 150 155 160 Thr Val Asn Tyr Tyr Met Thr Thr Ile Ala Gly Met Phe Gln Phe Ala 165 170 175 Thr Asp Asn Gly Tyr Thr Ser Gly Asn Pro Phe Asn Gly Leu Ala Pro 180 185 190 Leu Lys Lys Ser Lys Val Lys Pro Asp Pro Leu Thr Arg Asp Glu Phe 195 200 205 Ile Arg Phe Ile Glu Ala Cys Arg His Gln Gln Thr Lys Asn Leu Trp 210 215 220 Ile Leu Ala Val Tyr Thr Gly Ile Arg His Gly Glu Leu Val Ser Leu 225 230 235 240 Ala Trp Glu Asp Ile Asp Leu Lys Ala Arg Thr Ile Thr Ile Arg Arg 245 250 255 Asn Tyr Thr Lys Leu Gly Glu Phe Thr Pro Pro Lys Thr Asp Ala Gly 260 265 270 Thr Gly Arg Thr Ile His Leu Val Gln Pro Ala Ile Asp Ala Leu Lys 275 280 285 Ser Gln Ala Glu Met Thr Met Leu Gly Lys Gln His Ser Val Glu Val 290 295 300 Lys Gln Arg Glu Tyr Gly Arg Thr Ala Val His Lys Cys Thr Phe Val 305 310 315 320 Phe Ser Pro Gln Val Thr Lys Gln Gln Gln Leu Ser Gly Pro His Tyr 325 330 335 Lys Val Asp Ser Ile Arg Glu Ser Trp Thr Ser Ile Leu Lys Arg Ala 340 345 350 Gly Leu Arg His Arg Lys Ser Tyr Gln Ser Arg His Thr Tyr Ala Cys 355 360 365 Trp Ser Leu Ala Ala Gly Ala Asn Pro Ser Phe Ile Ala Ser Gln Met 370 375 380 Gly His Thr Asn Ala Gln Met Val Phe Asn Val Tyr Gly Ala Trp Met 385 390 395 400 Lys Asp Asn Asn His Glu Gln Ile Glu Leu Leu Asn Lys Arg Leu Ser 405 410 415 Glu Ser Val Pro Cys Met Pro His Lys Lys Ala Gly * 420 425 <210> 630 <211> 46897 <212> DNA <213> Escherichia coli O157:H7 <400> 630 atgatttaaa atcttcccca aaactttccc caaaaccctt ccccaaaact ggctattttc 60 tatgctgttt tgatatctac gataatccag tctttaccac gatcatcatt gtatcggtcg 120 gtcatttttc tggatttatg acctaacaac ttttgcgtat ccagaccctg ttcccgatat 180 aaccgttctg acagagatcg ctgctcatga aatgtgggcg cagttccttg ctcccatttt 240 atgccacatt tttccctggc ctttttaaaa gccgttgtaa gagtatttgc agacacctgg 300 tctcctctgt ttgcttgaga ggtagtgtga cggtaatgga ccagatattt actaacaaca 360 gcatccctgc actgagatat aacttcacga agggtaatat tcagagcatc gcatttcagg 420 ttaagcggaa tagcaagttt tgaaccggtt ttttcctgag taatgtgcaa catgtcgtcc 480 cagatatcag agaatttcaa attgcagata tcgcttaaac gttgtccagt gacaagagca 540 agtagcatcc cgcattttaa atagggctgc cgtctgctta cgctgtcaaa tattgcctgc 600 cattcgggca gtgataatct ttgacggttt actcgatttc gcggttgttt tgttgcctgc 660 gctgggttaa atcctggcgg aacatgtcct gcgtgttgtg cttctttgaa gacgtcgatc 720 aacaccattc tcacgacttg cgccatcctg ttatgacctt cagcctttac agcatcaatt 780 atttcggcaa tatcaagtgc ggtaatatcc ttgaggtgtt gcattccaca atgctcacgg 840 aaaagacgga tgggtttgcc tttttgccga taggagttgg gtcttagttc attatgttgc 900 agcctgtcct cctggataga attatattta tcaagccatt ctgtcaccgt aatgtctgag 960 cgcctgcctt tcattctttc cagacgctca ttgacgctta atatttgtcg ggtacgttgt 1020 tcagcaataa tggtatttgc ttcagtagca acttgttttg cttcattctc atcagttcct 1080 aagctatgaa aacgaccgga tagtggatgt ttgtattgcc aatatacctt tccggttcgc 1140 ttatctaatt tgcaatataa attgggtata gagattttgt gagatcgggg gctagcagcc 1200 atcagcgatt atccgttgga gttttgggtt tgcgtttatt gggagttgcg gttctgcaag 1260 cgttcctaca aaacgggaat ttcggtcaat catccagtag cgaccaactt ttatagcggg 1320 tggggccatc attttccctt gcgcgtattt tttcagaact cgctcacttg gtgctaagtc 1380 cccaaattct tctttagccc agtcccgtaa agtgattagt cgagacattt gtcctcctct 1440 tagctgctga gggagtttgt gaccgatata tctgacatga tattaagctc atggcaggta 1500 catctcttga ctggtcatag agataaattt aatgctgaga aatgcagtat tgaatttatc 1560 aatttttcac cagcttctgg tctttctggc tgtcatgcgc aaaacatatg gctttaataa 1620 aaaactggat tgggttagca acgagcaact ttccgaatta accgggatat tgccgcacaa 1680 gtgttctgct gcaaaaagtg ttctggtaaa gcgtgggatt tttattcaga gcgggcggaa 1740 taccggcatt aataatgtgg tcagtgaatg gtcaacatta cccgaatcag gtaagaaaaa 1800 taaagtttac ctgaaagagg taaatttacc tgaatcaggt aaaaaaagtt tacccaaatc 1860 aggtaaaggc gtttacccga atcaggtaaa cacaaaagac aaactaacaa aagacaatat 1920 aaaacctttt tcgtccgaga attctggcga atcctctgac caaccagaaa acgatcttcc 1980 tgtggtgaaa ccggatgctg caattcagag cggcagcaag tgggggacag cagaagacct 2040 gaccgccgca gagtggatgt ttgacatggt gaagaccatc gcgccatcag ccagaaaacc 2100 gaattttgca gggtgggcta acgatatccg cctgatgcgt gaacgtgacg gacgtaacca 2160 ccgcgacatg tgcgtgctgt tccgctgggc atgccaggac aacttctggt ccggtaacgt 2220 gctaagtccg gccaaactcc gcgacaagtg gacccagctc gaaatcaacc gtaacaagca 2280 acaggcaggc atgatagcca gcaaaccaaa actcgacctg acaaacactg actggattta 2340 cggggtggat ttatgaaaaa catcgccgca cagatggtta actttgaccg tgagcagatg 2400 cgtcggatcg ccaacaacat gccggaacag tacgacgaaa agccgcaggt acagcaggta 2460 gcgcagatca tcaacggtgt gttcagccag ttactggcaa ctttcccggc gagtctggct 2520 aaccgtgacc agaacgaact gaacgaaatc cgccgccagt gggttctggc tttccgggaa 2580 aacgggatca ccacaatgga acaggttaac gcaggaatgc gcgtagcccg tcggcagaat 2640 cgaccatttc tgccatcacc cgggcagttt gttgcatggt gccgggaaga agcatccgtt 2700 atcgccggac tgccaaacgt cagcgagctg gttgatatgg tttacgagta ttgccggaag 2760 cgtggcctgt atccggatgc agagtcttat ccgtggaaat cgaacgcgca ttactggttg 2820 gttaccaact tgtaccagaa catgcgggcc aatgcgctga ctgacgcgga attacggcgc 2880 aaggctgccg atgaactgac ctgtatgaca gcgcgaatta accgtggtga gacgatacct 2940 gaaccagtaa aacaacttcc tgttatgggc ggtagacctc taaatcgtgc acaggctctg 3000 gcgaagatcg cagaaattaa agctaagttc ggactgaaag gagcaagtgt atgacgggca 3060 aagaggcaat tattcattac ctggggacgc ataagagctt ctgtgcacag gacgttgccg 3120 cggtaacagg tgcaaccgta accagcataa atcaggctgc ggctaaaatg gcgcgggcag 3180 gaatcctggt cgttgatggt aaggtctggc gaacggtgta ttaccggttc gctaccagag 3240 aagaacggga aggaaaggtg agcacgaatc tgatttttaa ggagtgtcgc cagagtgccg 3300 cgatgaaacg ggtattgagg gtatataaaa gaacatcaat gggtacacaa tgatgaaaca 3360 ggtgagttga gttcaaactg tagtacaatt ctctccagtt tgaacaggaa agaatatgtt 3420 atgaaccctt atatttatct tggtggtgca atacttgcag aggtcattgg tacaacctta 3480 atgaagtttt cagaaggttt tacacggtta tggccatctg ttggtacaat tatttgttat 3540 tgtgcatcat tctggttatt agctcagacg ctggcttata ttcctacagg gattgcttat 3600 gctatctggt caggagtcgg tattgtcctg attagcttac tatcatgggg gtttttcggc 3660 caacggctgg acctgccagc cgttataggc atgatgttga tttgtgccgg tgtgttggtt 3720 attaatttat tgtcacgaag cacaccacat taaaaataat ttcttttaaa agactgcaat 3780 atggcggttc atatctttac atgggccgct tttgttaatg tttttagttt ttgtgtattc 3840 ttttgtgcct tcaagattat tgcgtaagca aattgcaata cgattattgt tgtatattca 3900 agatagtgtg atcgtaattg tctttttaaa taaaaattaa acaaaaatta tatctcacca 3960 ctaaggttta taaaagcata agttagcagg tgtcaccatg aaaaaagcca tagcatatat 4020 gcgattttca tcaccaggtc agatgtctgg cgactcatta aaccgacaga gaagacttat 4080 tgctgaatgg ttaaaggtaa atagtgatta ttatcttgat accataacat atgaagattt 4140 aggattaagt gcattcaaag gaaagcatgc acaatcagga gctttttcgg aatttttaga 4200 tgctatagag catggttata tattgccagg aactacattg ttagttgaaa gtctggacag 4260 actttcaaga gaaaaagtcg gtgaagcgat tgaacgtctg aaattgattt tgaatcacgg 4320 tattgatgtt ataactcttt gcgacaatac agtctataat attgactctt tgaatgagcc 4380 atattcatta ataaaagcca tacttatagc acaaagggca aatgaagaaa gcgagataaa 4440 gtcaagtcgg gttaaattat catggaagaa aaaacggcag gatgcactgg aatcaggtac 4500 gattatgacg gcgtcttgtc cgagatggct ctccttagat gacaaaagaa cggcttttgt 4560 tccagacccc gacagggtga aaactattga gctaattttt aaactcagga tggaaaggcg 4620 ctcattgaat gcaatagcca agtatttaaa tgatcatgct gtaaagaatt tctcaggaaa 4680 agaaagtgca tgggggcctt ctgtaattga aaaattatta gcgaataaag ctctgatagg 4740 tatatgcgta ccttcatatc gtgcaagagg gaaagggata agtgaaatcg ctggctatta 4800 tcccagagtc atatcagatg atttgtttta cgctgtacag gaaattcggt tggcaccttt 4860 tggtattagc aatagtagca agaatcctat gctaataaat ctacttcgaa cagttatgaa 4920 gtgtgaggct tgtggtaata ccatgattgt tcatgcggta tctggaagtt tgcatggcta 4980 ttatgtttgt ccgatgagaa gattacatcg atgtgacagg ccatcaataa agagagattt 5040 ggttgattat aatatcatta atgaattgct ttttaattgt agcaaaattc aaccagttga 5100 aaacaagaaa gatgctaatg aaactttaga gttaaaaatt attgagcttc agatgaaaat 5160 taataattta atcgttgcat tgtctgtcgc gcctgaagtt accgctatag cagagaaaat 5220 aagactatta gataaggaat tacgaagagc tttggtatca ttgaaaactt tgaagagtaa 5280 aggtgtaaat tcattcagtg atttttatgc tattgactta accagtaaaa atggacgaga 5340 gttatgccgt acacttgcct ataaaatatt cgaaaaaatc ataattaata cggataataa 5400 aacctgtgat atctatttta tgaatggcat tgtttttaaa cactatcctt taatgaaagt 5460 aatatccgcc cagcaggcga taagtgctct caaatatatg gttgatggtg aggtttattt 5520 ttgagtaata atcacttttt caaccgtgct atggtatgaa agtaaagtaa ctactatgat 5580 attaactatc gagcaagaat atccccaggc actcaacagg gcgcaggtca acgtgaatcg 5640 gtcatgacac gacaccgatt ttgcggaatc aatgttgctt atgaatacaa catcccgctt 5700 agtacatgtt caacacatca gcaaattttg aactgggtgt ggcacttaac tgaaaaaaca 5760 tggatgacac aaaatgttac tcgtcgcttc attgaagtag cttgtggata tcacaagcta 5820 gactatcgcc aatgatattc aatttttgat tttttagtat caaccttcca taataatgtc 5880 accggagctt gaacaactcc ggtgacttct gcgcatttaa ggggacttaa atgcgaccac 5940 aatctgaact ccttaccttg tcacagatgc agaaatgcac ctgcgatgtc ttgcatccag 6000 cgtttgatct ctgcggaggt gaagcgtgaa cctcccacaa gatggcatca aattacatcg 6060 cggtaacttc accgctgtcg gtcagcagat ccagacttat ctggaagacg gcaaatgctt 6120 tcgcatggtg cttaaaccgt ggcgcgagag acgcagtctt tcccagaatg cactcagcca 6180 catgtggtac agcgaaatca gtgaatacct catcagcagg gggaaatcgt tcgctacttc 6240 agcatgggta aaagatgctc tcaaacacac atacctcggt tatgaaacca aggacctggt 6300 tgatgtcgta accggcgaaa tcactactat ccagtcgtta cgccatacct ccgatcttgg 6360 taccggagag atgtatgtct tcctgtgtaa ggttgaagcc tgggcgatga atattggctg 6420 ccacctgact attccacaga gctgcgagtt ccagctgctg cgtgacaagc aggaggcgta 6480 atggctacac cgcttattcg tgtcatgaac ggacacatct acaaagtacc aaatcgtcgt 6540 aagcgtaaac ctgagctgaa gccatccgaa ataccaacac tgctcggata taccgccagc 6600 ctggttgata aaaaatggtt gcgactggca gcaaggagga atcatggctg atttgagaaa 6660 agcagcgcgt agtcgggaat gccaagtaag aatccctggc gtatgtaatg gcaaccctga 6720 aacgtctgta ctggcacata tccggctgac tggattgtgc ggcaccggta ccaaaccgcc 6780 agacttgatt gccaccattg catgttctgc ctgccacgac gaaatcgacc gccgcacaca 6840 ttttgtcgat gctgcatatg caaaagaatg cgcgctggaa ggtatggcga gaacacaggt 6900 tatctggctg aaagaggggg ttattaaggc gtgaatacct acagcatcac attaccctgg 6960 cctccgagca ataatcgcta ctaccggcat aatcgcgggc gcacgcacat cagcgcagaa 7020 gggcaggcat accgtgataa cgtcgcccga atcatcaaag gctccatgct ggatatcggc 7080 ctggctatgc cagtgaaaat ccgtattgag tgccacatgc cggatcgccg tcgccgtgac 7140 ctggataatc tgcaaaaagc cgcttttgac gcactcacca aagcaggttt ctggctggat 7200 gatgctcagg tcgttgatta ccgtgttgtg aagatgcccg ttaccaaagg tgggaagctg 7260 gagctgacca tcaccgaact ggggaatgaa tgatgtttga gtcttatatg gcagaacgtc 7320 ttcgccaccg ctggatgcgc ctgcgcttat atcgttttcc tggttctgtt ttgaccgatt 7380 accggatact gaagaattac gccaaaacac tgaaaggagc tgccgcatga atacccaata 7440 tttacagtat gtccgcgagc aactcattgt ggctaccgct gatttgagcg gagcaacgaa 7500 aggacagctt gaagcctggc tggagcatgc acaatttgat actggtacat acaaacgaaa 7560 gaagccgcgc attctggatg aggtaactgg caggatgatt acgctggata atccgccgat 7620 ttccggtaag cagtcgtacg caaaaggttc atccattgca ctggtcagcc aggttgagtt 7680 ctcaacctcg tcatggcgcc gcgcggttct gtctctcgaa gaacatcaga aagcgtggtt 7740 gctgtggagt tacagcgaaa gtgttcgctg ggaacatcag gtcaccataa cgcagtgggc 7800 atggagcgag tttaagactc tgttgggtac caggaaaatt gcaggtaaga cactggaacg 7860 tttgaagaag ttgatctggc tggcggcaca ggatgtgaag aacgagctgg cagggcgtaa 7920 gacctatgaa taccaggagc tggcatcact ggtgggagtg acatcaaaaa actggtctga 7980 gacatttact gaacgctggg ttgcaatgaa acacattttt ctacagcttg atagccaagc 8040 tttattgctt ttaacgaaaa cacgttcaaa acaaaagacc acattttcac agcaagatat 8100 tgcaaaactg gattaaaaat catatatttt atgtaaatct gatattttgc caatgttgta 8160 cgcactggca gtaatccaaa ttcaagcccg aggtttaaag ccttgggctt ttctgtttct 8220 gaacggtgag tagccttcca acctacccca gccagggggt cttcagctgt tgagttgata 8280 ttgcttagcc ctctgttgcc agctacatgc tggctttttt attccaggct tgtggggagc 8340 atcaactccg tgctttgtcg ttaaattacc ccgtgagcct gatttctgac atttaacgtc 8400 ccggcctttt gtcggcggcg aaacattggc tattcatatg cacgaaaaag agagccttgc 8460 cggagcgttc tggctcgttt tgctgatcat cgcaggttgg ggcggtctgg tccgctacct 8520 gatagatgtg aagcagagta aagcaacgtg gagttggata aatgctctgg ctcaaatagt 8580 ggtatcagga ttcaccggtg ttattggtgg cctgatcagc atcgaaagtg gattcagtat 8640 ttacatgatt ctcgcgacag cggggattag tggtgcgatg ggttcggttg cactgacgta 8700 cttctgggaa cgactgacag gggtgaaaaa tgcaaaatct taatcctcag cgtaaagcct 8760 tcctcgatat gttggcgtgg tcagaaggaa cggataacgg gcgacaaccg acacgtaacc 8820 acggttatga tgttattgtt ggcggcgaac tgtttactga ttactccgat caccctcgca 8880 aacttgtcac gctacacccc aaactcaaat caacagccgc cggacgttat cagcttcttt 8940 cacgctggtg ggatgcttac cgtaaacagc ttggtttgaa agacttctcc cccaaaagcc 9000 aggacgcagt ggcattgcag cagattaaag agcgtggtgc tttacctatg attgatcgcg 9060 gtgatatccg tcaggcaatc gaccgttgca gtaatatctg ggcttcactg ccgggcgctg 9120 gttatggtca gttcgagcat aaggctgaca gcctgattgc aaaattcaaa gaagctggcg 9180 gaacggtcag agagagtgag gtatgagcag aataaccgcg attatctccg ctctgctcat 9240 ctgcatcatc gtctgcctgt catgggctgt taatcattac cgtgataacg ccattaccta 9300 caaagcccag cgcgacaaaa atgccagaga actgaagctg gcgaacgtgg caattactga 9360 catgcagatg cgtcagcgtg atgttgctgc gctcgatgca aaatacacga aggagttagc 9420 tgatgcgaaa gctgaaaatg atgctctgca tgatgatgtt gccgctggtc gtcgtcggtt 9480 gcacatcaaa gcagtctgtc agtcagtgcg tgaagccacc accgcctccg gcgtggataa 9540 tgcagcctcc ccccgactgg cagacaccgc tgaacgggat tatttcaccc tcagagagag 9600 gctgatcact atgcaaaaac aactggaagg aacccagaag tatattaatg agcagtgcag 9660 atagagctgc ccatatcgat gggcagctca tgcaattatt gtgagcaata cacacgcgct 9720 tccagcggag tataaatgcc taaagtaata aaaccgagca atccatttac gaatgtttgc 9780 tgggtttctg ttttaacaac attttctgcg ccgccacaaa ttttagctgc atcgacagtt 9840 ttcttctgcc caattccaga gacgaagaaa tggtgggtga tggtttcctt tggtgttact 9900 gctgccggtt tgttttgaac agtaaacgtc tgttgggcac atcctgtaat aagcagggcc 9960 agcgcagtag cgagtagcat ttttttcatg gtgttattcc cgatgctttt taaagttcgc 1002 0 agaatcgtat gtgtagaaaa ttaaacaaac cctaaacaat gagttgaaat ctcatattgt 1008 0 taatatttat taatgtatgt cagatgcgaa ggatcgtcac tgtattcccg gattaactat 1014 0 gtccgcagcc ctgacaggga aactcctctg cgggagtgtc cgggaataat taataacgat 1020 0 gcacacaggg tttagcgcgt acacgtattg cattatgcca acgccccggt gctgacacgg 1026 0 aagaaaccgg acgtgatgat ttagcgtgga aagatttgtg tagtgttctg aatgctctca 1032 0 gtaaatagta atgaattatc aaaggcatag taatatcttt tatgttcgtg gatatttgta 1038 0 acccatcgga aaactcctgc tttagcaaga ttttccctgt attgctgaaa tgtgatttct 1044 0 cttgatttca acctatcata ggacgtttct ataagatgcg tatttcttga gaatttaaca 1050 0 ttcacaacct ttttaagtcc ttttattaac acagtgttat cgttttctaa cacaatgtga 1056 0 atattatctg tggctagata gtaaatataa tgtgagacat tgtgacgttt tagttcagaa 1062 0 taaaacaatt cacagtttaa atcttttcgc acttgatcga atatttcttt aaaaatggca 1068 0 acctgagcca ttggtaaaac cttccatgtg atacgagggc gcgtagtttg cattatcgtt 1074 0 tttatcgttt caatctggtc tgacctcttt gtgttttgtt gatgatttat gtcaaatatt 1080 0 aggaatgttt tcaattaata gtattggttg cgtaacaaag tgcggtcctg ctggcattct 1086 0 ggagggaaat acaaccgaca gatgtatgta aggccaacgt gctcaaatct tcatacagaa 1092 0 agatttgaag taatatttta accgctagat gaagagcaag cgcatggagc gacaaaatga 1098 0 ataaagaaca atctgctgat gatccctccg tggatctgat tcgtgtaaaa aatatgctta 1104 0 atagcaccat ttctatgagt taccctgatg ttgtaattgc atgtatagaa cataaggtgt 1110 0 ctctggaagc attcagggca attgaggcag cgttggtgaa gcacgataat aatatgaagg 1116 0 attattccct ggtggttgac tgatcaccat aactgctaat cattcaaact acttaacctg 1122 0 tgacagagcc aacacgcagt ctgtcactgt caggaaagtg gtaaaactgc aactcaatta 1128 0 ctgcaatgcc ctcgtaatta agtgaattta caatatcgtc ctgttcggag ggaagaacgc 1134 0 gggatgttca ttcttcatca cttttaattg atgtatatgc tctcttttct gacgttagcc 1140 0 tccgacggca ggcttcaatg acccaggctg agaaatttcc ggaccctttt tgatcaagag 1146 0 cgatgttaat ttgttcaatc atttggttag gaaagcggat gttgcgggtt gttgttctgc 1152 0 gggttctgtt cttcgttgac atgaggttgc cccgtattca gtgtcgctga tttgtattgt 1158 0 ctgaagttgt ttttacgtta agttgatgcg gatcaattaa tacgatacct gcgtcataat 1164 0 tgattatttg acgtggtttg atggcgtaga tgcacgttgt gacatgtaga tgataattat 1170 0 tatcattttg cgggtccttt ccggcgatcc gacaggttac ggggcggcga cctcgcggtt 1176 0 tttcactatt tatgaaaatt ttccggttta aggcgtttcc gttcttcttc gccgtaacct 1182 0 aatgttttta tttaaaacac cccctgaaaa gaaaggaaac gacaggtgct gaaaacgggc 1188 0 tttttggcct ctgtcgtttc ctttctctgt ttttgtccgt ggaatgaaca atggaagtca 1194 0 acaaaaagca gctggctgac attttcggcg cgagtatccg taccattcag aactggcagg 1200 0 agcagggaat gcccgttctg cggggtggtg gcaagggtaa tgaggtactt tatgactctg 1206 0 ccgccgccat aaaatggtat gccgaaaggg atgctgaaat tgagaacgaa aagctgcgcc 1212 0 gggaagttga agaactgagg caggacagcg agacagatct ccagccaggg actattgagt 1218 0 acgaacgcca tcgacttacg cgtgcgcagg ccgacgcaca ggaactgaag aatgccagag 1224 0 actcagctga agtggtggaa accgcattct gtactttcgt gctgtcgcgg atcgcaggtg 1230 0 aaattgccag tattctcgac gggatccccc tgtcggtgca gcggcgtttt ccggaactgg 1236 0 aaaaccgaca tgttgatttc ctgaaacggg atatcatcaa agccatgaac aaagcagccg 1242 0 cgctggatga actgataccg gggttgctga gtgaatatat cgaacagtca ggttaacagg 1248 0 ctgcggcatt ttgtccgcgc cgggcttcgc tcactgttca ggccggagcc acagaccgcc 1254 0 gttgaatggg cggatgccag ttactatctc ccgaaagaat ccgcatacca ggaagggcgc 1260 0 tgggaaacac tgccctttca gcgggccatc atgaatgcga tgggcagtga ctacatccgc 1266 0 gaggtgaatg tggtgaagtc tgcccgtgtt ggttattcca aaatgctgct gggtgtttat 1272 0 gcctacttca tagagcataa gcagcgcaac acccttatct ggttgccgac ggatggtgat 1278 0 gccgagaact ttatgaaaac ccacgttgag ccgactattc gtgatattcc gtcgctgctg 1284 0 gcgctggccc cgtggtatgg caaaaagcac cgggataaca cgctcaccat gaagcgtttc 1290 0 accaatgggc gtggcttctg gtgcctgggc ggtaaagcgg caaaaaacta ccgtgaaaag 1296 0 tcagtggatg tggcgggtta tgatgaactt gctgcctttg atgaggatat tgaacaggaa 1302 0 ggctctccga cgttcctggg cgataagcgt attgaaggct cggtctggcc aaagtccatc 1308 0 cgtggctcca cgcccaaagt gagaggcacc tgccagattg agcgtgcagc cagtgaatcc 1314 0 ccgcatttta tgcgttttca tgttgcctgc ccgcactgcg gggaggagca gtaccttaaa 1320 0 tttggcgaca aagagacgcc gtttggcctc aaatggacgc cggatgatcc ctccagcgtg 1326 0 ttttatctct gcgagcataa tgcctgcgtc atccgtcagc aggagctgga ctttactgat 1332 0 gcccgttata tctgcgaaaa gaccgggatc tggacccgtg atggcattct ctggttttcg 1338 0 tcatccggtg aagagattga accgcctgac agtgtgacct ttcacatctg gacggcgtac 1344 0 agcccgttca ccacctgggt tcagattgtc aaagactgga tgaagacgaa aggggatacg 1350 0 ggaaaacgta aaaccttcgt gaacaccacg ctcggtgaga catgggaagc gaagatcggc 1356 0 gaacgtccgg atgctgaagt gatggcagag cggaaagagc attattcagc gtccgttcct 1362 0 gaccgtgtgg cttacctgac cgccggtatc gactcccagc tggatcgcta cgaaatgcgc 1368 0 gtatggggat gggggccggg tgaggaaagc tggctgattg atcggcagat tattatgggc 1374 0 cgccacgacg atgaacagac gctgctgcgt gtggatgagg ccatcaataa aacctatacc 1380 0 cgccggaatg gtgcagaaat gtcggtatcc cgtatctgct gggatactgg cgggattgac 1386 0 ccgactattg tgtatgaacg ctcgaaaaag catgggctgt tccgggtgat ccccattaaa 1392 0 ggggcatccg tctacggaaa gccggtggcc agcatgccac gtaagcgaaa caaaaacggg 1398 0 gtttacctta ccgaaatcgg tacggatacc gcgaaagagc agatttataa ccgcttcaca 1404 0 ctgacgccgg aaggggatga accgcttccc ggtgccgttc acttcccgaa taacccggat 1410 0 atttttgatc tgaccgaagc gcagcaactg actgctgaag agcaggtcga aaaatgggtg 1416 0 gatggcagga aaaaaatact gtgggacagc aaaaagcgac gcaatgaggc gctcgactgc 1422 0 ttcgtttatg cgctggcggc gctgcgcatc agtatttccc gctggcagct ggatctcagt 1428 0 gcactgctgg cgagcctgca ggaagaggat ggtgcagcaa ccaacaagaa aacactggca 1434 0 gaatacgccc gtgccttatc cggagaggat gaatgacgcg acaggaagaa cttgccgctg 1440 0 cccgtgcggc actgcatgac ctgatgacag gaaaacgggt ggcaacggta cagaaagacg 1446 0 gacggcgagt ggagtttacg accacttccg tgtctgacct gaaaaaatac attgctgagc 1452 0 tggaagtgca gaccggcatg acacagcgac gcaggggacc tgcaggattt tatgtatgaa 1458 0 aatgtccacc attcccaccc ttctggggcc ggacggcatg acatcgctgc gtgaatatgc 1464 0 cggttatcac ggcggtggca gcggatttgg tgggcagttg cgggcgtgga acccaccggg 1470 0 tgaaagtgtg gatgcagccc tgctgcccaa ctttacccgt ggcaatgccc gcgcagacga 1476 0 tctggtacgc aataacggct atgccgccaa cgccatccag ctgcatcagg atcatatcgt 1482 0 cgggtctttt ttccggctca gtcatcgccc aagctggcgc tatctgggca tcggggagga 1488 0 agaagcccgt gccttttccc gcgaggttga agcggcatgg aaagagtttg ccgaagatga 1494 0 ctgttgctgc attgacgttg agcgaaaacg cacgtttacc atgatgattc gggaaggtgt 1500 0 ggccatgcac gcctttaacg gtgaactgtt cgttcaggcc acctgggata cccgtccctc 1506 0 gcgactgttc cggacacagt tccggatggt cagcccgaag cgcatcagca acccgaacaa 1512 0 taccagcgac agccggaact gccgtgccgg tgtgcagatt aatgacagcg gtgcggcgct 1518 0 gggatattac gtcagcgagg acgggtatcc tggctggatg ccgcagaaat ggacatggat 1524 0 accccgcgag ttacccggcg gtcgcgcttc gttcattcac gtctttgaac ccgtggagga 1530 0 cgggcagacc cgcggtgcaa atgtgtttta cagcgtgatg gagcagatga agatgctcga 1536 0 cacgctgcag aacacgcagc tgcagagcgc cattgtgaag gcgatgtatg ccgccaccat 1542 0 tgagagtgag ctggatacgc agtcagcgat ggattttatt ctgggcgcga acagtcagga 1548 0 gcagcgggaa aggctgaccg gctggattgg tgaaattgcc gcgtattacg ccgcagcacc 1554 0 ggtccgtctg ggaggcgcaa aagtgccgca cctgatgccg ggggactcac tgaacctgca 1560 0 gacggctcag gacacggata acggctactc cgtgtttgag cagtcactgc tgcggtatat 1566 0 cgctgccggg ctgggtgtct cgtatgagca gctttcccgg aattacgccc agatgagcta 1572 0 ctccacggca cgggccagtg cgaacgagtc gtgggcgtac tttatggggc ggcgaaaatt 1578 0 cgtcgcatcc cgtcaggcga gccagatgtt tctgtgctgg ctggaagagg ccatcgttcg 1584 0 ccgcgtggtg acgttacctt caaaagcgcg cttcagcttt caggaagccc gcagtgcctg 1590 0 ggggaactgc gactggatag gctccggtcg tatggccatc gatggtctga aagaagttca 1596 0 ggaagcggtg atgctgatag aagccggact gagcacctac gagaaagagt gcgcgaaacg 1602 0 cggtgacgac tatcaggaaa tttttgccca gcaggtccgt gaaacgatgg agcgccgcgc 1608 0 agctggtctt aaaccgcccg cctgggcggc tgcggcattt gaatccgggc tgcgacaatc 1614 0 aacagaggag gagaagagtg acagcagagc tgcgtaatct cccgcatatt gccagcatgg 1620 0 cttttaatga gccgctgatg cttgaacccg cctatgcgcg ggttttcttt tgtgcgcttg 1626 0 caggccagct tgggatcagc cgcctgacgg atgcagtatc cggcgacagc ctgactgccg 1632 0 gagaggcacc cgcggcgctg gcgttatccg gtgatgatga cggaccacga caggcccgga 1638 0 gttatcaggt catgaacggc atcgccgtgc tgccggtgtc cggtacgctg gtcagccgga 1644 0 cgcgggcgct gcagccgtat tcgggaatga ccggttacaa cggcattatc gcccgtctgc 1650 0 aacaggctgc cagcgatccg atggtggacg gcattctgct cgatatggac acaccgggcg 1656 0 ggatggtggc gggagcattt gactgtgctg acatcatcgc ccgtgtgcga gacataaaac 1662 0 cggtatgggc gctggccaac gacatgaact gcagtgcagg tcagctgctt gccagcgccg 1668 0 cctcccggcg tctggtcacg cagaccgccc ggacaggctc catcggcgtc atgatggctc 1674 0 acagtaatta cggtgctgcc ctggagaaac agggcgtgga aatcacgctg atttacagcg 1680 0 gcagccataa ggtggatggc aacccctaca gccatctacc gggtgatgtc cgggaaacac 1686 0 tgcagtcccg gatggatgca acccgccgga tgtttgcgca gaaggtgtcg gcatataccg 1692 0 gcctgtccgt gcaggctgtg ctggataccg aggctgcagt gtacagcggt caggaggcca 1698 0 ttgatgccgg actggctgat gaacttgtca acagcaccga tgcgatcacc gttatgcgtg 1704 0 atgcactgga tgcacgtaaa tcccgtctct caggagggcg aatgaccaaa gagactcaat 1710 0 caacaactgt ttcagccact gcttcgcagg ctgacgttac tggcgtggtg ccagcgacgg 1716 0 agggcgaaaa cgccagcgcg gcgcagccgg acgtgaacgc gcagatcacc gctgcggttg 1722 0 cggcagaaaa cagccgcatt atggggatcc tcaactgtga ggaggctcac ggacgcgaag 1728 0 aacaggcccg cgtgctggca gaaacccccg gtatgaccgt ggaaacggcc cgccgcattc 1734 0 tggccgcagc accacagagt gcacaggcgc gcagtgatac tgcgctggat cgtctgatgc 1740 0 agggggcacc ggcaccgctg gctgcaggta acccggcatc tgatgccgtt aacgatttgc 1746 0 tgaacacacc agtgtaaggg atgtttatga cgagcaaaga aacctttacc cattaccagc 1752 0 cgctgggcaa cagtgacccg gctcataccg caaccgcgcc cggcggattg agtgcgaaag 1758 0 cgcctgcaat gaccccgctg atgctggaca cctccagccg taagctggtt gcgtgggatg 1764 0 gcaccaccga cggtgctgcc gttggcattc ttgcggttgc tgctgaccag accagcacca 1770 0 cgctgacgtt ctacaagtcc ggcacgttcc gttatgagga tgtgctctgg ccggaggctg 1776 0 ccagcgacga gacgaaaaaa cggaccgcgt ttgccggaac ggcaatcagc atcgtttaac 1782 0 ctgacccttc atcactaaag gccgcctgtg cggctttttt tacgggattt ttttatgtcg 1788 0 atgtacacaa ccgcccaact gctggcggca aatgagcaga aatttaagtt tgatccgctg 1794 0 tttctgcgtc tctttttccg tgagagctat cccttcacca cggagaaagt ctatctctca 1800 0 caaattccgg gactggtaaa catggcgctg tacgtttcgc cgattgtttc tggtgaggtt 1806 0 atccgttccc gtggcggctc cacctctgaa tttacgccgg gatatgtcaa gccgaagcat 1812 0 gaagtgaatc cgcagatgac cctgcgtcgc ctgccggatg aagatccgca gaatctggcg 1818 0 gacccggctt accgccgccg tcgcatcatc atgcagaaca tgcgtgacga agagctggcc 1824 0 attgctcagg tcgaagagat gcaggcagtt tctgccgtgc tcaagggcaa atacaccatg 1830 0 accggtgaag ccttcgatcc ggttgaggtg gatatgggcc gcagtgcggc gaacaacatc 1836 0 acgcagtccg gcggcacgga gtggagcaag cgtgacaagt ccacgtatga cccgaccgac 1842 0 gatatcgaag cctacgcgct gaacgccagc ggcgtggtga atatcatcgt gtttgacccg 1848 0 aaaggctggg cgctgttccg ttccttcaaa gccgtcaggg agaagctgga tacccgtcgc 1854 0 ggctctcatt ccgaactgga gacagcggta aaagacctgg gcaaagcggt gtcttataag 1860 0 ggaatgtatg gcgatgtggc catcgtcgtg tattccggac agtacgtgga aaacggcgtc 1866 0 aaaaagaact tcctgccgga caacacgatg gtgctgggga acactcaggc acgcggtctg 1872 0 cgcacctatg gctgcattca ggatgcggac gcacagcgcg aaggcattaa cgcctctgcc 1878 0 cgttacccga aaaactgggt gaccaccggc gatccggcgc gtgagttcac catgattcag 1884 0 tcagcaccgc tgatgctgct ggctgaccct gatgagttcg tgtccgtaca actggcgtaa 1890 0 tcatggccct tcggggccat tgtttttctg tggaggagtc catgacgaaa gatgaactga 1896 0 ttgcccgtct ccgctcgctg ggtgaacaac tgaaccgtga tgtcagcctg acggggacga 1902 0 aagaagaact ggcgctccgt gtggcagagc tggaagagga gcttgatgac acggatgaaa 1908 0 ctgccggtca ggacacccct ctcagccggg aaaatgtgct gaccggacat gaaaatgagg 1914 0 tgggatcagc gcagccggat accgtgattc tggatacgtc tgaactggtc acggtcgtgg 1920 0 cactggtgaa gctgcatact gatgcacttc acgtcacgcg ggatgaacct gtggcatttg 1926 0 tgctgccggg aacggcgttt cgtgtctctg ccggtgtggc agccgaaatg acagagcgcg 1932 0 gcctggccag aatgcaataa cgggaggcgc tgtggctgat ttcgataacc tgttcgatgc 1938 0 tgccattgcc cgcgccgatg aaacgatacg cgggtacatg ggaacgtcag ccaccatgac 1944 0 atccggtgag cggtccggcg cagtaatacg tggtgttttt gatgaccctg aaaatatcag 1950 0 ctatgccgga cagggcgtgc gtgttgaagg ctccagcccg tccctgtttg tccggactga 1956 0 tgatgtgcgg caactgcggc gtggagacac gctgaccatc ggtgaggaaa acttctggat 1962 0 agaccggatt tcgacggatg atggcggaag ctgtcatctc tggcttgggc ggggcgtacc 1968 0 gcctgccgtt aaccgtcgtc gctgaagggg ggatgtatgg ccataaaagg tcttgagcag 1974 0 gccgttgaaa acctcagtcg tatcagcaaa acggcggtgc ctggtgcgtc agcaatggcc 1980 0 attaaccgcg ttgcttcatc cgcgatatcg cagtcggcgt cacaggttgc ccgtgagaca 1986 0 agagtacgcc ggaaactggt aaaggaaagg gccaggctga aaagggccac ggttaaaaat 1992 0 ccgcaggcca gaatcaaggt taaccggggg gatttgcccg taatcaagct gggtaacgcg 1998 0 cgggttgtcc tgtcccgacg caggcgtcgt aaaaaggggc agcgttcatc cctgaaaggt 2004 0 ggcggcagcg tgcttgtggt gggaaaccgt cgtattcccg gcgcgtttat tcagcaactg 2010 0 aaaaatggcc ggtggcatgt catgcagcgt gtggccggga aaaaccgtta ccccattgat 2016 0 gtggtgaaaa tcccgatggc ggtgccgctg accacggcgt ttaaacagaa tattgagcgg 2022 0 atacggcgtg aacgtcttcc gaaagagctg ggctatgcgc tgcagcatca actgagaatg 2028 0 gtaataaagc gatgaaacat actgaactcc gtgcagccgt actggatgca ctggagaagc 2034 0 atgacaccgg ggcgacgttt tttgatggtc gccccgctgt ttttgatgag gcggattttc 2040 0 cggcagttgc cgtttatctc accggcgctg aatacacggg cgaagagctg gacagcgata 2046 0 cctggcaggc ggagctgcat atcgaagttt tcctgcctgc tcaggtgccg gattcagagc 2052 0 tggatgcgtg gatggagtcc cggatttatc cggtgatgag cgatatcccg gcactatcag 2058 0 atttgatcac cagtatggtg gccagtggct atgactaccg gcgcgacgat gatgcgggcc 2064 0 tgtggagttc agccgatctg acttatgtca ttacctatga aatgtgagga cgatatgcca 2070 0 acaccaaatc ctctggcacc ggtgaaaggg gccgggacca cactgtgggt ttataacggg 2076 0 aacggcgacc catatgcaaa cccgctttca gacaatgact ggtcgcgtct ggcaaaggtt 2082 0 aaagacctga cgcccggcga actgaccgct gagtcctatg acgacagtta tctcgatgat 2088 0 gaagatgcgg actgggccgc gaccggacag gggcagaaat ccgctggaga taccagcttc 2094 0 acgctggcgt ggatgcccgg agagcagggg cagcaggcgc tgctggcgtg gtttaatgaa 2100 0 ggtgataccc gtgcctataa aatccgcttc ccgaacggca cggtcgatgt gttccgcggc 2106 0 tgggtcagca gtatcggtaa ggcggtgacg gcgaaggaag tgatcacccg cacggtgaaa 2112 0 gtcaccaacg tgggacgtcc gtcgatggca gaagatcgca gcacggtaac agcggcaacc 2118 0 ggcatgaccg tgacgcctgc cagcacctcg gtggtgaaag ggcagagcac gacgctgacc 2124 0 gtggcattcc agccggaagg cgcaaccgac aagagcttcc gtgcggtgtc tgcggataaa 2130 0 acaaaagcca ccgtgtcggt cagtggtatg accatcaccg tgaaaggtgt tgctgcaggc 2136 0 aaggtcaaca ttccggtcgt atccggtaat ggtgagtttg ctgcggttgc agaaatcaac 2142 0 gtcaccgcca gttaatccgg agaatcagcg atgttcctga aaaccgaatc atttgaacat 2148 0 aacggcgtga ccgtcacgct ttctgaactg tcagccctgc agcgtattga gcatctcgcc 2154 0 ctgatgaaac ggcaggcaga acaggcggag tcagacagca accggaagtt tactgtggaa 2160 0 gacgccatca gaaccggcgc ttttgtggtg gcgatgtccc tgtggcataa ccatccgaag 2166 0 aagacgcaga tgccgtccat gaatgaagcc gttaaacaga ttgagcagga agtgcttacc 2172 0 acctggcccg cggaggcaat ttctcatgct gaaaacgtgg tgtaccggct gtccggtatg 2178 0 tatgagtttg tggtgaatga tgcccctgaa caggcagagg acgccgggcc tgcagagcct 2184 0 gtttctgcgg gaaagtgttc gacggtgagc tgagttttgc cctgaaactg gcgcgcgaga 2190 0 tggggcgacc cgactggcgt gccatgcttg ccgggatgtc atccacggag tatgccgact 2196 0 ggcaccgctt ttacagtacc cattattttc atgatgttct gctggatatg cacttttccg 2202 0 ggctgacgta caccgtgctc agcctgtttt tcagcgatcc ggatatgcat ccgctggatt 2208 0 tcagtctgct gaaccggcgt gaggctgacg aagagcctga agatgatgtg ctgatgcaga 2214 0 aagcggcagg gcttgctgga ggcgttcgtt ttggcccgga cgggaatgaa gttatccccg 2220 0 cttccccgga tgtggcggac atgacggagg atgacgtaat gctgatgaca gtatcagaag 2226 0 ggatcgcagg aggagtccgg tatggctgaa ccggtaggcg atctggtcgt tgatttaagt 2232 0 ctggatgcgg ccagatttga cgagcagatg gccagagtca ggcgtcattt ttccggtacg 2238 0 gaaagtgatg cgaaaaaaac agcggcagtc gttgaacagt cgatgagccg gcaggcgctg 2244 0 gctgcacaga aagcgggaat ttccgtcggg cagtataaag ccgccatgcg tatgctgcct 2250 0 gcgcagttca ctgacgtggc cacgcagctt gcaggtgggc aaagtccgtg gctgatcctg 2256 0 ctgcaacagg gggggcaggt gaaggactcc ttcggcggga tgatccccat gttccggggg 2262 0 cttgccggtg cgatcaccct gccgatggtg ggggccacct cgctggcggt ggcgaccggt 2268 0 gcgctggcgt atgcctggta tcagggcaac tcaaccctgt ccgatttcaa caaaacgctg 2274 0 gtcctttccg gcaatcaggc cgggctgacg gcagatcgta tgctggtcct gtccagagcc 2280 0 gggcaggcgg cagggctgac gtttaaccag accagcgagt cactcagcgc actggttaag 2286 0 gcgggggtaa gcggtgaggc tcagattgcg tccatcagcc agagtgtggc gcgtttctcc 2292 0 tctgcatcag gcgtggaggt ggacaaggtc gctgaagcct tcgggaagct gaccactgac 2298 0 ccgacgtcgg ggctgacagc gatggcgcgc cagttccata acgtgacggc ggagcagatt 2304 0 gcgtatgttg ctcagttgca gcgttccggc gaagaagccg gggcattgca ggcggcgaac 2310 0 gaggccgcga cgaaagggtt tgatgaccag acccgccgcc tgaaagagaa catgggcacg 2316 0 ctggaaacct gggcagacag gacagcacgg gcattcaaat ccatgtggga tgcggtgctg 2322 0 gatattggtc gtcctgatac cgcgcaggag atgctgatta aggcagaggc cgcgtttaag 2328 0 aaagcggacg atatctggaa tctgcgcaag gatgattatt ttgttaacga tgaagcgcgg 2334 0 gcgcgttact gggatgatcg tgaaaaggcc cgtcttgcgc ttgaagccgc ccgaaagaag 2340 0 gctgagcagc agagtcaaca ggacaaaaat gcgcagcaac agagcgatac cgaagcgtca 2346 0 cggctgaaat ataccgaaga ggcgcagaag gcttacgaac gcctgcagac gccgctggag 2352 0 aaatataccg cccgtcagga agaactgaat aaggcactga aagacgggaa aatcctgcag 2358 0 gcagattaca acacgctgat ggcggcggcg aaaaaggact atgaagcgac gctgaaaaag 2364 0 ccgaaacagt ccggcgtgaa ggtgtctgcg ggcgatcgtc aggaagacag tgctcatgct 2370 0 gccctgctga cgcttcaggc agaactccgg atgctggaga agcatgccgg agcgaatgag 2376 0 aaaatcagcc agcagcgccg ggatttgtgg aaggcagaaa gtcagttcgc ggtactggag 2382 0 gaggcggcac aacgtcgcca gctgtccgca caggagaaat ccctgctggc gcataaagac 2388 0 gagacgctgg agtacaaacg ccagctggct gtacttggcg acaaggtcac ctatcaggag 2394 0 cacctgaacg cgctggcaca gcaggcggat aaattcgcac agcaacaacg ggcaaaacgg 2400 0 gccgccattg atgcaaaaaa ccgggggctg actgaccggc aggcagcgcg ggaagccacg 2406 0 gaacagcgcc tgaaggaaca gtatggcgat aatcctctgg cgctgaataa cgtcatgtca 2412 0 gagcagaaaa agacctgggc agctgaagac cagcttcgcg ggagctggat ggcaggcctc 2418 0 aggtcaggct ggagtgagtg ggaagagagc gccacggaca gtatgtcgca ggttaaaagt 2424 0 gctgccacgc agacctttga tggtattgca cagaatatgg cggcgatgct gaccggcagt 2430 0 gaacagaact ggcgcagctt cacccgttcc gtgctgtcca tgatgacaga aattctgctt 2436 0 aagcaggcaa tggtggggat tgtcggaagt ataggcagcg ccattggcgg cggcgcatca 2442 0 gcgtcaggcg gtacagccat tcaggcagct gcggcgaaat tccattttgc ggccggaggg 2448 0 tttacgggaa ccggcggcaa atatgagcca gcggggattg ttcaccgtgg tgaatttgtc 2454 0 ttcacgaagg aggcaaccag ccggattggc gtaggaaatc tttaccggct gatgcgcggc 2460 0 tatgccaccg gcggttatgt cggtacaccg ggcagcatgg cggacagccg gtcgcaggcg 2466 0 tccgggacgt ttgagcagaa taaccatgtg gtgattaaca acgacggcac gaacggtcag 2472 0 atagggccac aggcactgaa ggcggtttat gacgtagccc gtaaggcggc aatggatgtt 2478 0 gtgaccgggc agatgcgcga tggtggtctg ttctccggag gtggacgatg aaaaccttcc 2484 0 gctggaaagt gaaacccggt atggatgtgg cttcggcccc ttccgtaaga aaggtgcgct 2490 0 ttggtgatgg ctattcccag cgagcgcctg ccgggctgaa tgccgacctg aaaacgtaca 2496 0 gcgtgacgct ttctgttccc cgttgggagg ccacggcgct tgagtcgttt ctggctgagc 2502 0 acgggggctg gaaggccttt ctgtggacgc cgccttatga gtggcggcag ataaaggtga 2508 0 cctgcgcaaa atggtcgtcg cgggtcagta tgctgcgtgt tgagttcagc gcagagtttg 2514 0 aacaggtggt gaactgatgc aggatatccg gcaggaaaca ctgaatgaat gcacccgtgc 2520 0 ggagcagtcg gccagcgtgg tgctctggga aatcgatctg acagaggtcg gtggagaacg 2526 0 ttattttttc tgtaatgagc agaacgaaaa aggtgagccg gtcacctggc aggggcgaca 2532 0 gtatcagccg tatcccattc aggggagtgg ttttgaactg aatggcaaag gcaccagtac 2538 0 gcgccccacg ctgacggttt ctaacctgta cggtatggtc accgggatgg cggaagatct 2544 0 gcagagtctg gtcggcggaa cggtggtccg gcgtaaggtt tacgcccgtt ttctggatgc 2550 0 ggtgaacttc gtcaacggaa acagtgacgc cgatccggag caggaggtga tcagccgctg 2556 0 gcgcattgag cagtgcagcg aactgagcgc ggtgagtgcc tcttttgtac tgtccacgcc 2562 0 gacggaaacg gacggcgctg tttttccggg acgtatcatg ctggccaaca cctgcacctg 2568 0 gacctatcgc ggcgatgagt gcggttatca cggtccggcg gtcgcggatg aatatgacca 2574 0 gccaacgtcc gatatcacga aggataaatg cagcaaatgc ctgagcggtt gtaagttccg 2580 0 caataacgtc ggcaactttg gcggcttcct ttccattaac aaactttcgc agtaaatccc 2586 0 atgacacaga cagaatcagc gattctggcg cacgcccggc gatgtgcgcc agcggagtcg 2592 0 tgcggcttcg tggtaagcac gccggagggg gaaagatatt tcccctgcgt gaatatctcc 2598 0 ggtgagccgg aggcgtattt ccgtatgtcg ccggaagact ggctgcaggc agaaatgcag 2604 0 ggtgagattg tggcgctggt ccacagccac cccggtggtc tgccctggct gagtgaggcc 2610 0 gaccggcggc tgcaggtgca gagtgatttg ccgtggtggc tggtctgccg ggggacgatt 2616 0 cataagttcc gctgtgtgcc gcatctcacc gggcggcgct ttgagcacgg ggtgacggac 2622 0 tgttacacgc tgttccggga tgcttatcat ctggcgggga ttgagatgcc ggattttcat 2628 0 cgcgaggatg actggtggcg tcacggtcag aatctctatc tggataatct ggaggccaca 2634 0 gggctgtatc aggtgccgtt gtcatcagca caaccgggcg atgtgctgct gtgctgtttt 2640 0 ggttcatcgg tgccgaatca tgccgccatt tactgtggtg atggcgagct gctgcaccat 2646 0 attcctgaac aactgagcaa acgagagagg tataccgaca aatggcagcg acgcacacac 2652 0 tccctctggc gtcaccgggc atggcgcgca tctgccttta cggggatttg caacgatttg 2658 0 gccgccgcat cgaccttcgt gtgaaaacgg gggctgaagc catccgcgca ctggccacac 2664 0 agctcccggt gtttcgtcag aagctgagcg acggctggta tcaggtacgg attaccgggc 2670 0 gggacgtcag cacgtccggg ttaacggcgc agttacatga gactctgcct gatggcgctg 2676 0 tgattcatat tgttcccaga gtcgccgggg ccaagtcagg tggcgtattc cagattgtcc 2682 0 tgggggctgc cgccattgcc ggatcattct ttaccgccgg agccaccctt gcagcatggg 2688 0 gggcagccat tggggccggt ggtatgaccg gcatcctgtt ttctctcggt gccagtatgg 2694 0 tgctcggtgg tgtggcgcag atgctggcac cgaaagccag aactccccgt acacagacaa 2700 0 cggataacgg caaacagaac acctatttct cctcactgga taacatggtt gcccagggca 2706 0 atgttctgcc ggttctgtac ggtgaaatgc gcgtggggtc acgcgtggtt tctcaagaga 2712 0 tcagcacggc agacgaaggg gacggtggtc aggttgtggt gattggtcgc tgatgcaaaa 2718 0 tgttttatgt gaaaccgcct ccgggcggtt ttatcgttta tggagcatga cgaatgggta 2724 0 aaggcagcag taaggggcat accccgcgcg aagcgaagga caacctgaag tccacgcagc 2730 0 tgctgagtgt gatcgatgcc atcagcgaag ggccggttga aggtccggtg gatggattaa 2736 0 aaagcgtgct gctgaacagt acgccggtgc tggacagtga ggggaatacc aatatatccg 2742 0 gcgtcacggt ggtgttccgg gccggtgagc aggagcagac accgccggag ggatttgaat 2748 0 cctccggctc cgagacggtg ctcggtacag aagtgaaata tgacacgccg atcacccgga 2754 0 ccatcacgtc ggcaaacatt gaccgtctgc gttttacttt cggcgtgcag gcactggtgg 2760 0 aaaccacctc aaagggggac aggaatccat cggaagtccg cctgctggtt cagatacaac 2766 0 gtaacggtgg ctgggtgacg gaaaaagaca tcaccattaa gggtaaaacc acttcacagt 2772 0 atctggcctc ggtggtggtg gataacctgc cgccgcgccc gtttaatatc cggatgcgca 2778 0 ggatgacgcc ggacagcacc acagaccagc tgcagaacaa aacgctctgg tcgtcataca 2784 0 ccgaaattat cgatgtgaaa cagtgctacc cgaacacggc actggtcggc gtgcaggtgg 2790 0 actcggagca gttcggcagc cagaaggtga gccgtaatta tcatctgcgc gggcgtattc 2796 0 tgcaggtgcc gtcgaattat aacccgcaga cgcggcaata cagcggtatc tgggacggaa 2802 0 cgtttaaacc ggcatacagc aacaacatgg cctggtgtct gtgggatatg ctgacccatc 2808 0 cgcgctacgg catggggaaa cgtcttggtg cggcggatgt ggataaatgg gcgctgtatg 2814 0 tcatcggcca gtactgcgac cagtcagtgc cggacggctt tggcggcacg gagccgcgca 2820 0 tcacctgtaa tgcctacctg accacacagc gtaaggcgtg ggatgttctc agcgatttct 2826 0 gctcggcgat gcgctgtatg ccggtatgga acgggcagac gctgacgttc gtgcaggacc 2832 0 gaccgtcgga taaggtgtgg acctataacc gcagtaatgt ggtgatgccg gatgatggcg 2838 0 cgtcgttccg ctacagcttc agcgccctca aggaccgcca taatgccgtt gaggtgaact 2844 0 ggattgaccc ggataacggc tgggagacgg cgacagagct tgtggaggac acgcaggcca 2850 0 ttctccgtta cggtcgtaac gtcacgaaga tggatgcctt tggctgtacc agccgggggc 2856 0 aggcacaccg cgccgggctg tggctgatta aaacggagct gctggagacg cagaccgtgg 2862 0 atttcagcgt gggcgcagaa gggcttcgcc atgtaccggg cgatgtcatt gaaatctgtg 2868 0 atgatgacta tgcggggatc agcatcggtg ggcgtgtgct ggcggtgaac agccagaccc 2874 0 ggacgctgac gctcgaccgt gaaatcacgc tgccatcctc cggtaccacg ctgataagcc 2880 0 tggttgacgg aagtggcaat ccggtcagcg tggaggtcca gtccgtcacc gacggcgtga 2886 0 aggtaaaagt gagccgtgtt cctgacggcg ttgccggata cagcgtatgg gggctgaagt 2892 0 tgccgacgtt gcgccagcgc ctgttccgct gcgtgagtat ccgtgagaac gacgacggca 2898 0 cgtatgccat caccgccgtg cagcatgtac ccgaaaaaga agccatcgtg gataacgggg 2904 0 cgcactttga cggcgacctg agcggcacgg tgaatggcgt cacgccgccc gcggtgcagc 2910 0 acctgactgc cgaagtcacc gcagacagcg gggaatatca ggtgctggcg cgctgggaca 2916 0 cgccgaaggt ggtgaagggg gtgagcttcc tgcttcgcct gaccgtggca gcggacgatg 2922 0 gcagtgagcg gctggtcagt acggccagga cgacggaaac cacataccgc ttcacgcaac 2928 0 tggcgctggg gaactacagg ctgactgtcc gggcggtaaa tgcgtgggga cagcagggcg 2934 0 atccggcatc ggtatcgttc cggattgccg caccggcagc gccgtctcgg attgagctga 2940 0 caccaggcta ttttcagata accgccacgc cgcatcttgc ggtttatgat ccgacggtac 2946 0 agtttgagtt ctggttctcg gaaacgcgga ttgcggatat caggcaggtt gaaaccagcg 2952 0 cgcgttatct tggtacggcg ctgtactgga tagccgccag tatcaatatc aaaccgggcc 2958 0 atgattatta cttttatatc cgcagtgtga acaccgttgg caaatcggca ttcgtggagg 2964 0 ccgtcggtcg ggcgagcgat gatgcggaag gttatctgga ttttttcaaa ggcaagataa 2970 0 ccgaatctca tcttggtaaa gagctactgg aaaaagttga cctgacggag gataacgcca 2976 0 gcagactgga tgagttttcg aaagagtgga aggatgctaa cgataagtgg aatgccatgt 2982 0 ggggcgtcaa aattgagcag accaaagacg gcaaacatta tgtcgcgggt attggcctca 2988 0 gcatggagga cacggaggaa ggcaagctga gccagtttct ggttgccgcc aatcgtatcg 2994 0 cgtttattga cccggcaaac gggaatgaaa cgccgatgtt tgtggcgcag ggcaaccaga 3000 0 tattcatgaa cgacgtgttc ctgaagcgcc tgacggcccc caccattacc agcggtggaa 3006 0 atccaccggc attttccctg acaccggacg gaaagctgac tgctaaaaat gcggatatca 3012 0 gtggcagtgt gaatgcgaac tccgggacgc tcaacaacgt cacgattaat gagaactgtc 3018 0 agattaaggg gaaactgtca gccaatcaga ttgaaggcga tattgtcaaa acggtcagca 3024 0 agtctttccc ccgcacgagc acttatgcca gtggcaccat cacggtaaga atcagtgatg 3030 0 atcagaaatt tgaccggcag gtcatgatac cgccagtgtt attccgcggt ggtaagcatg 3036 0 agaatttcaa cagtaataac caacagtcat actggtattc aacctgccgg ttaagagtga 3042 0 cccgcaatgg ccaggagatt tttaatcagt ccacgacgga tgctcagggc gtattttcct 3048 0 cagttataga tatgcctgcc ggacagggga cgctgacact gacattcacc gtatcttcat 3054 0 caggagcgaa taactggaca ccaacaacca gtatcagcga tctgctggtt gtggtgatga 3060 0 aaaaatccac agcaggtatc agtatcagct gaattttata acccagaacg ggcgtcagaa 3066 0 atgacgcctt ttttattgca gaaaagcgag aggtaattat gcgtaaactt tatgccgcca 3072 0 ttttgtccgc agccatttgt ctggccgtat ccggtgcgcc tgcatgggca tctgaacatc 3078 0 agtccacgct gagcgcgggg tatcttcatg cccggaccaa cgttcccggc agtgatgatc 3084 0 tgaacgggat taacgtgaaa taccgttatg agtttacgga tacgctgggg ctggtgacgt 3090 0 cattcagcta tgcaggagac aagaatcgcc agcttacccg ttacagcgat acccgctggc 3096 0 atgaagattc cgttcgtaac cgctggttca gcgtaatggc ggggccgtct gtgcgcgtga 3102 0 atgaatggtt cagcgcgtat gcgatggcgg gtgtggctta cagccgtgtg tcgactttct 3108 0 ccggggatta tcttcgcgta actgacaaca aggggaaaac gcacgatgtg ctgaccggaa 3114 0 gtgatgacgg tcgccacagc aacacgtctc tggcgtgggg ggctggcgtg cagtttaacc 3120 0 cgaccgaatc cgtggccatt gatattgctt atgaaggctc cggcagtggc gactggcgca 3126 0 ctgacggttt catcgtgggt gtcggttata agttctgatt agccaggtaa cacagtgtta 3132 0 tgacagcccg ccggttcagg cgggcttttt tgtggggtga atatggcagt aaagatttca 3138 0 ggtgtactga aagacggcac aggaaaaccg gtagagaact gcaccattca actgaaagcc 3144 0 agacgtaaca gcgccacggt ggtggtgaac acggtggcct ctgaaaatcc ggatgaagcc 3150 0 ggtcgttaca gcatggacgt tgagtacggt cagtacagcg ttattctgtt ggtggaaggg 3156 0 ttcccgccgt cacatgccgg gaccatcacc gtgtatgaag attctcaacc cggtacgctg 3162 0 aatgattttc ttggtgccat gactgaggat gatgtccgtc cggaggcact gcgccgtttt 3168 0 gagctgatgg tggaagaggt ggcgcgtaac gcgtccgcgg tggcacagaa cacggcagcc 3174 0 gcgaagaagt cagccagcga tgccagcaca tcagcccgtg aggcggcaac ccatgcgact 3180 0 gatgctgcgg actcagcacg cgcagccagc acgtcagccg gacaggccgc gtcgtcggct 3186 0 cagtcagcgt cttccagcgc aggaacggca tcaacaaagg ctactgaagc atcaaaaagt 3192 0 gctgccgctg cagagtcctc aaaaagcgcg gcggctacca gtgccggtgc ggcgaaaacg 3198 0 tcagaaacga atgcggcagt gtcacaacaa tcagccgcca cttctgcatc caccgcgacc 3204 0 acgaaagcgt cagaagctgc ctcctcagcc agggatgcgt cggcttcaaa agaggcggca 3210 0 aaatcatcag aaacgagcgc agcctcgagc gccagtagtg cagcctcctc ggcaacggcg 3216 0 gcaggcaatt ccgcgaaggc ggccaaaacg tctgagacaa acgctaagtc ctctgaaacg 3222 0 gcagcagaac agagtgcctc cgcagcagca ggctcaaaaa cagcggctgc attatctgcc 3228 0 agtgccgcgt caacaagtgc cgggcaggcc tcagccagtg ccaccgccgc cggaaaatcg 3234 0 gcagaaagtg ccgcatcgtc tgcttcaaca gccacaacga aggctggcga agccactgaa 3240 0 caggccagcg cagcagcgag ttctgcttcc gcagcgaaga catccgaaac gaacgcgaaa 3246 0 gcgtcggaaa ccagcgcaga atcctcaaaa acggctgccg catcgtcagc cagttcggcg 3252 0 gcgtcatcgg catcatctgc gtctgcttca aaagatgagg cgaccagaca agcgtcagca 3258 0 gcgaagagca gcgccacgac ggcatccacg aaggcgacag aggcagctgg tagtgcgacg 3264 0 gcagcagctc agagcaaaag tacggcggaa tctgcagcaa cgcgcgctga gacagcggca 3270 0 aaacgggcag aggatattgc atccgccgtg gcgcttgagg atgcgagcac gacgaaaaag 3276 0 gggatagtac agctcagcag tgcgactaac agcacttccg agtcactggc ggcaacgcca 3282 0 aaagccgtta aggccgcgta tgagctggct aacgggaaat acaccgcaca ggatgcaacg 3288 0 acagcacaga aagggatagt tcagcttagc aacgcgacca acagcacatc tgaaatgctg 3294 0 gcggcaacgc caaagtcggt aaaggcagcc tatgaccttg ctaacgggaa atatactgct 3300 0 caggacgcta cgacagcaca aaaaggaatt gtccagctca gtagtgcaac caacagcgca 3306 0 tctgaaacgc ttgccgcgac accgaaagca gtgaaagcag ctaatgataa tgcgaatggt 3312 0 cgggtacctt ctgcccgtaa ggtgaatggt aaggcgcttt catcggatat aacactgacg 3318 0 ccgaaagata ttggtacgct taactcaaca acaatgtcat tcagcggtgg tgctggttgg 3324 0 ttcaaattag caacggtaac catgccacag gcgagttctg ttgtttcaat tacgttgatt 3330 0 ggtggcgcgg gatttaacgt ggggtcacct caacaggcag gtatatctga acttgttttg 3336 0 cgtgcaggta atggtaatcc gaaggggatt actggtgctt tatggcagcg cacatcgaca 3342 0 gggtttacaa attttgcctg ggtcaataca tctggtgata cttacgatat ttacgttgca 3348 0 atcggaaatt atgcgactgg tgtaaatatt caatgggatt ataccagtaa tgccagcgtg 3354 0 acgattcata cgtcaccagc atattctgct aataagccgg aagggttaac ggacggtaca 3360 0 gtttattcac tctatacgcc atcagagcag ttttatccgc ctggcgcacc aatcccgtgg 3366 0 ccatcagata ccgttccgtc tggctatgcc ctgatgcagg ggcagacttt tgacaaatct 3372 0 gcatacccga aacttgcagc cgcttatccg tcaggcgtga tccctgatat gcgtggctgg 3378 0 acgattaagg gcaaacctgc cagtggtcgg gccgtattgt ctcaggaaca ggacggcatt 3384 0 aaatcgcaca cccacagcgc cagcgcatcc agtacggatt tggggacgaa aaccacatcg 3390 0 tcgtttgatt acggcactaa atccacgaat aacaccgggg cgcacacgca cagtgtgagc 3396 0 ggtacagccg caagtgccgg aaaccatact catagtgtca caggcgcatc agcagtcagc 3402 0 cagtggtcac aaaatgggtc agtacataag gtagtgtctg cggccagtgt gaatacaagt 3408 0 gctgcaggag cgcacactca tagtgtcagc ggcacagctg catctgcagg tgctcacgca 3414 0 catactgtcg gtattggtgc tcatacgcac tctgttgcga ttggctcaca tggacacacc 3420 0 atcaccgtta acgctgcggg taacgcggaa aacactgtca aaaacatcgc atttaactac 3426 0 attgtgaggc ttgcataatg gcattcagaa tgagtgaaca accacggacc ataaaaattt 3432 0 ataatctgct gaccggaact aatgaattta ttggtgaagg tgacgcatat attccgcctc 3438 0 atacaggtct gccagcaaac agtacctata ttgcaccgcc agatattccg gctggcttcg 3444 0 tggctgtttt caacagtgat gagtcatcgt ggcatctcgt tgaagatcat cggggtaaaa 3450 0 cggtttatga cgtggcttcc ggcgacgcgt tatttatttc tgaactcggc tcattaccgg 3456 0 aaaatgttac ctggttatcg ccggaagggg agtttcagaa gtggaacggc acagcctggg 3462 0 tgaaagatgc agaagcagaa aaactgttcc ggatccggga ggcggaagaa acaaaaaaca 3468 0 gcctgatgca ggtagccagt gagcatattg cgccacttca ggatgctgta gatctggaaa 3474 0 tcgcaacgga ggaagaagcc tcattgctgg aagcctggaa aaagtatcgg gtgttgctga 3480 0 accgtgttga tacatcaact gcacctgata ttgagtggcc tgtaatacct gaagtttaaa 3486 0 ataaaagccc gcttaaaata tcgcgggctt cgaaatataa atgtattttc agaggctaga 3492 0 gcttaggata tctcagcggc aattaactta tgagggatag ctaaatacca gaagataatt 3498 0 agtttttact atttatcttt gtttgtggtt ctccttcagc aagctcagcg ccagtgacag 3504 0 gattgatgtc ttcatgggat ttcaaccttg ttgccatagc ttttatcata gcttcttgct 3510 0 tggtcgaaag atttatcgag gccttcccat ccccaccgtc aaccgctgaa actggatcgg 3516 0 aaacatagtc aaagttttca tcactgttcc aactacctct gacgtcttca ccttctgaca 3522 0 tgttgtaata tacgtttttg tatttctcaa gtggtggtaa ttttcctggt ggaaaggtgt 3528 0 tacgaattga atgtaatgct ttttcaaatg aaagcatgtg tgctgcttcc cgggtcatta 3534 0 aaaatgccag agtgtctttt actccaggat catcagtaac attaatgaga cgttcgtaaa 3540 0 tgatctttgc ccgagcttca gctgcaatat ttgaacgaag atcggccgtg acttcgccaa 3546 0 tagtatcaac ataagctgca gtccagggta ctccagctga attagttaat gctgggcctc 3552 0 ctccgtagag gagagaagtt atatggctat cattgccatt ttgagttaag gaacggtaaa 3558 0 gctcagcttc attctcagtt ccttcagcaa gtgctccttt tgcacctttg ttgagcatac 3564 0 caacaagaga accaataatt tcgagatgac ttagttcttc tgttgctatg tccatcagca 3570 0 tatcccttcg gcctgcatct tcatcactta agccttgagt gaagtatcgg catgctgctg 3576 0 caagctcacc ctgtggccca ccgaattgtt ctaagagtag attagccaag cctgggtttg 3582 0 gctcacttac acgtactgta tattgaagtt ttttcacgtg tctaaacata atgcctcctc 3588 0 aaaagaatta ttttttggct tcaactccat caatttcaga tctgaccatg aattgctcag 3594 0 tggtgtcagg aatatggtta agaagccatt cagccatttg tttttcttca ttaagaattg 3600 0 cttcaataat gggtactgaa gctgtatcac ccgcattttt ggctgctgcg agaagagatg 3606 0 tgtaacacgc aatttcaaat tgttcgaaca catagccact gatcgaacct ttgacaattt 3612 0 catcagatgg aaaaattcca ccaatggatt gtccaaacgc ggccatttta ctcatagagt 3618 0 ctttaatgac agagcgcgaa atattattac gatcaagtat gctttcaagc tgtgaaagct 3624 0 ggttctttgt ttcgctaatg tgctgctcaa ttctggaacg taactcagga tagttttcta 3630 0 tccggctggc catagactca agcatttttt cagcttgttt ttccatcgca tgtgcatcac 3636 0 gaagccagtc atggtaatgt tcaattctat tcataatctg tttatcctaa aagaaattga 3642 0 agtctatagt tcaggagtta tcctgagctt ttttattaac gttattaaat gccaggtctg 3648 0 ttaatttgac atcagtagct ttttcctctt ccagtgtttc tttcaggagt ttagccgctt 3654 0 ttttatatcc taattgctca gcgagtgtta ccaaagtgcc ataactggca atttcatagt 3660 0 gctctacttt ttgtgctgca gcaatcaatg cagcatcacg tacttcattt ttatcagtgc 3666 0 tttcaattac ctcattcgcc tcttcgataa gtccttccat tgcggcacac ttaattcttt 3672 0 tcaatttaag accatcttca gaatcaacaa cctgatcgat gcgttcaatt tgaccatgtg 3678 0 tctcatcaag atgtgactga aaagcagcgg ttaatttatc actatatgca gagcgactaa 3684 0 gtttagacag tgcctttgtt agttgtttct cagcgctgta tgtatccgat aataagtgga 3690 0 tgaagatatc ttcaacagat ttaatttgca taatcactcc agagttttca ctgcgagccc 3696 0 gtaggctcgc agttagcttc agttattcac gaatgtaggg ggtgataaat taagagtcag 3702 0 atttacggcc gccaccatgg ctattctgac cacctttttt ccctgcttct gatgctcttt 3708 0 gtggatcgtt tttaaaatta ccgccactat gttggccgcc tttacgacca gcgtcagaag 3714 0 ctttttgtcg atcttcagcg aaattacctg caccgccacg atgttcggtc atatcatttc 3720 0 tcctctgatt ttcaaattgt aaataacatg tgccttgtca gcacccaatt aactctagta 3726 0 acaaataaga aagtgtcaaa taagagattg gtatgcgcat cttaatgtga gaaatagcaa 3732 0 ttgtaaaaat gtgtactcag tgagtataat ctgttgatat cttggtgatt aacggaaagt 3738 0 ttaggttgta actcaaaaga ttaataaatc taaatttaca tttctatatc ttttgatgtg 3744 0 tatggcgttg tttttctcaa tcagaacatt ctaaaaaata atttaattac acggcggtag 3750 0 ttgttaatgt ttttacgact cttcctaatg aagtctgttt cttggataaa tagagaaatt 3756 0 ttatcttaag gactaattac aaaaacatct atatagccac aggaatcatt attgtactta 3762 0 actacaatat ttgagagtaa aaattaaacc gcagacacgg cgtatgcaag aacgtgctgc 3768 0 ggttggatgc tattttttcc ctgaagcgga aaacattact acagtacctt gaaccttggt 3774 0 tttaacattc tcgaaatgct ctgagagtat atgtgttaag ccttcttcgg aatcttttgt 3780 0 gtttgaaaag atgcctttct gattgtaaat gcgcatcagt ttttgaccga agctattgtg 3786 0 cacaactcca tcgccaagaa ttgtggctcc gtatagagtt ccatcgtcag ttaaggcctg 3792 0 cgccgcattg cgtattacac agctttttgt agatatattt ccaggcaggc agtgaagaag 3798 0 gtaaaacatg gaaatggaat caaattgacc atgtaacgcc gcgggataag gttcaaaaac 3804 0 atcatggcta attttatgtt taatttttga ttccccagcc cttgtagatg ccgcgttcag 3810 0 gctagcttcg ttcaaatcca ttaaagatat cagactactc tcaggtacgt gagtaaggta 3816 0 aaacccagtt ccaacaccaa tatccagatg gttgttacct aaatgttcca gaaagtgtgg 3822 0 aagaaggtgt tcctttgtag gacatcccca tgcaagacga tttgatactc ccaaaaccca 3828 0 ccagtcataa agctttaggg taagtggtgt gtaaatttta gccccatcat ctgtgttttt 3834 0 tttcattaat ttcaccatgt tatagtttta tttgtgaatt aaatcaatta tggcgatgaa 3840 0 ttacaagggg ttaaatgctg ccgcagcata gcgatattga aatagcctgg tatgctgcga 3846 0 tacagcagga gccgaatggc tggaagaccg tcaccacaca gttctacatc caggaattca 3852 0 gtgagtatat tgcgccactg caggatgctg tagatctgga aatcgcaacg gaggaagaaa 3858 0 gatcgttgct ggaggcatgg aataaatatc gggtattgtt gaatcgtgtt gatacatcag 3864 0 tagctcgtaa gcgtacagcc tgaaccgtct ggtcagaatc tgacgaatta gacaaagtgg 3870 0 tgcccaccaa ataagtagtg ggaaccaaag tatcagatat gcagaaaaat gtgactcccg 3876 0 gcaggcgaaa aggctgccct aattatcctc ccgaatttaa acagcagctc gttgctgcct 3882 0 cctgtgaacc cgggatatcc atctcaaaac ttgctcttga aaatggcatt aacgcaaatc 3888 0 tgttgttcaa atggcgacaa caatggcgcg agggaaagct gctattacct tcttcagaga 3894 0 gcccccagct acttcctgtg actctcgatg cagctgccga acagccagaa tcgctcgcag 3900 0 aggacccgga aaccctcagt atcagctgtg aggtaacgtt ccggcacggg acgctccgct 3906 0 tcaatggcaa tgtcagcgaa aagctcctga ctctgctgat acaggaactg aagcgatgat 3912 0 cccgttacct tccgggacca aaatttggct ggttgccggt atcaccgata tgagaaatgg 3918 0 cttcaacggc ctggctgcga aagtacaaac ggcgctgaaa gacgatccca tgtccggcca 3924 0 tgttttcatt ttccggggcc gcagcggcag tcaggttaaa ctgctgtggt ccaccggtga 3930 0 cggactgtgc ctcctgacca aacggctgga gcgtgggcgc ttcgcctggc cgtcagcccg 3936 0 tgatggcaaa gtgttcctta cgcaggcgca gctggcgatg ctgctggaag gtatcgactg 3942 0 gcgacagcct aagcggctgc tgacctccct gaccatgctg taaatctctt tatcctggtt 3948 0 gtcacagaat aagcccggta aaatacgggc ttatgaacga catctcttct gacgacatct 3954 0 tcctgctgaa acagcgcctg gccgaacagg aagcgctgat ccacgccctg caggaaaagc 3960 0 tgagcaaccg ggagcgcgaa atagaccatc tgcaggcgca gctggataaa ctccgccgga 3966 0 tgaacttcgg cagtcgttcc gaaaaagtct cccgccgtat cgcacaaatg gaagccgatc 3972 0 tgaaccggct tcagaaagag agcgatacgc tgactggtag ggtgtatgac ccggcagtac 3978 0 agcgtccgtt gcgtcagacc cgcacccgta agccgttccc tgaatcacta ccccgtgacg 3984 0 aaaagcgact gttgcctgcg gcgccgtgct gcccgaactg cggcggttca ctgagctatc 3990 0 tgggcgagga taccgccgaa cagctggagt tgatgcgtag cgccttccgg gttatccgga 3996 0 cggtacggga aaaacatgcc tgtactcagt gcgatgccat cgtgcaggca cctgcacctt 4002 0 cgcggcccat cgagcggggt atcgccggac cggggctgct ggcccgcgtg ctgacctcga 4008 0 agtatgcaga gcacaccccg ctgtatcgcc agtcagaaat atacggccgg caaggtgtgg 4014 0 agctgaggcg ttcactgctg tcgggctggg tggatgcatg ctgccggctg ctgtctccgc 4020 0 tggaagaggc gcttcatggc tatgtcatga ctgacggcaa actccatgcc gatgataccc 4026 0 cggtccaggt actgctgccg ggtaataaga agacgaagac cgggcggttg tgggcgtatg 4032 0 ttcgtgatga ccgcaatgca gggtcagcgt tggcacctgc agtgtggttc gcttacagcc 4038 0 cggacagaaa aggcatccat ccgcagactc atcttgcctg cttcagcggt gtgctgcaag 4044 0 cggatgcgta cgccgggttc aacgagctgt atcgcaatgg tgggataacg gaagctgcct 4050 0 gctgggctca tgcccgccga aagatccacg atgtgcacgt ccgcatcccg tcagcactga 4056 0 cggaagaagc cctggagcag atcggtcagt tgtacgccat agaggcggat ataaggggaa 4062 0 tgccggcaga gcagcggctt gctgaacgtc agcgaaaaac gaaaccgttg ttgaaatccc 4068 0 tggaaagctg gttgcgtgaa aagatgaaga ccctgtcgcg acactcagag ttggcgaagg 4074 0 cgttcgcgta cgcacttaac cagtggccgg cactgacgta ctatgcgaac gatggctggg 4080 0 tggaaatcga caacaacatc gctgaaaatg ccctgcgggc ggtcagtctg ggtcgtaaaa 4086 0 acttcctgtt cttcggctct gatcatggtg gtgagcgggg agcgctactg tacagcctga 4092 0 tcgggacgtg caaactgaat gacgtggatc cagaaagcta ccttcgccat gtgcttggcg 4098 0 tcatagcaga ctggccggtc aaccgggtca gcgaactgct tccgtggcgc atagcactgc 4104 0 cagctgaata acacatcccc gtcaatacgg ccctcgctgt acgcttacag tagctctggg 4110 0 tatgaagctg tttgtaactc atgttacagt aatggctatt actatctcga aggtgcaaaa 4116 0 tgtatattga tttgatattt tataaattta cttcgaatct ggcacgtcaa cttttgatta 4122 0 aagtaatatc agttttcggc gaaaaaagga ccgtgtacat gagacgattt catacaagaa 4128 0 taacaaaaat atgaatatgc tcccaatgca atatatgttt tgcattggga gcaaatagcg 4134 0 gaatattttg aaattattgt atttctgctt cagaatttcc tgggcagtat atattttcta 4140 0 ttttttgtgg agtgatcagg tgatgtacaa ctgctttatc tacacataaa ttaactccgg 4146 0 tgagagctaa tgtatgccca tcaccattta ttgttagtaa cgggctggaa aatttctctg 4152 0 ccatcttacg ggcattaatc cagggcgttg ttgggtcgta tttgtgtgct acaaacagta 4158 0 aaccagaggg cagaacagta tttttcaggc gagttttgtt caggtcgcta tgtattggcc 4164 0 ataattcaca aaaatcaggt gaatcggaac gtccattgtc aaagttaata gccgggaagg 4170 0 cattcgcaag agcctctttt cggaattttc gctcttctgg tgttaattgc tcatccccct 4176 0 gatctacaca aaggattacc cccgaagcat cacttgactc ttctgaggct atcggagcac 4182 0 tgagcgcagt ttcaatttca ttactgacaa tcccctgaga gaactggcgt atggcagttg 4188 0 caagggttgg ccatgatgaa cgccatagca gaaggtctgt tgttaatgat atgagttcat 4194 0 ctgaagatat attttctccc ttactgtcta ataaaggttt gtgatgtaat tttgataata 4200 0 gctcatggaa ctgagttatt gccttatctc tgtctgaaga aagcgggcaa ctttttgtac 4206 0 gcgcacacca ggatgcaaag cgatcaaacg tttcctgata actctgtgcc tgtttgagtt 4212 0 gccatgtgaa gttgtcctcc aggtcatcga tatcgacgac tccatcaaga acgatagatc 4218 0 ttacgttgta gggaaaacgt tctgcatata aggctgcaat ttgagttcca tacgaatacg 4224 0 ccacggctgt cagttgttta tcccccaagg cttgcctaat acgatcaata tcgtatacag 4230 0 cctcgttaga gccgatatgg cgaatgactt cggctccggt attatggata caggcattaa 4236 0 ttttatttaa tacttgttgc ttttcggtta tgttttcctg agtctctgta tctgattgcc 4242 0 ggcagtttat tgtcggagtg gactgcccga cgcctcgagg atcaaatcca ataatatccc 4248 0 atgactcacg aagatttgtg actggccagt caaagttaat ataaggattt atgcctggta 4254 0 acccgggacc accacttatt atcaggatac ttcctttatg cttgcttttt gccggcaatt 4260 0 ttgtcaacgc tagtttgact tgtgattttt tttcataaga agcatctccg cctgtgtctg 4266 0 tatattttaa tggaacagac aaataaccac atagtaagtc aggagacggt ttttcctcac 4272 0 caaaccagtg gttgaattga ctggccatac aggattgcca ctgtatctgc tgggcagata 4278 0 cggttactgg tagaagtaac gttaaaacaa ctttgaaatg agtaattatt tttcgcattg 4284 0 tgtctctgaa tatcggaata aagataaaat ttgaatatat tgaggtcttg tgttgcggta 4290 0 agagattaca cgttatgaca taggttaaat gcttacaaaa ttagtggata ttgtctactt 4296 0 gtaactgtaa acaaattccc cggggttata caataccacc ggggagaaaa tctggttaac 4302 0 ttcgttaaaa ggtgtactta agaccagcag tagtgatgaa gttatagttt tctatgcctg 4308 0 caccattttt gctgtagtct gaagtgttat cattgtgatc ataaagtgaa gtattacctt 4314 0 ttttattcgt aacccgattc catgtgcctt caacataaac ttttgcgtta ggtgttacgt 4320 0 aataacctgc attgactgaa acagaatagt aattttggtc tttgacttta ctgcgataag 4326 0 tgattctttt tcctgggtca tagtgctcat cgttatcaga tgcttccacc cagccgctgt 4332 0 atttaaatgt gccacctagc tcaaaatctt cataacgata acttccagtc aagccaatgt 4338 0 agggcatttt aaaacgttgt ttgtagccga ttgctctttc tccattcggg aaggagccga 4344 0 tatcatctct gaatccctcc tcagaactgt agatatagga accacctctg gctgtaaagc 4350 0 tataacggct ttcctgatat ccggccatga gtcccaggcg gtaattgggt tcgttgagga 4356 0 gccagccttt gatattcaga tcaaattcgt tggcataatt gagttgtgta tcagggtgtc 4362 0 tactttcatc cgtccaggtt ccggggttac tggaatccat ccagtcctga tcgaccatat 4368 0 tgccacctcg gctgccgaga gttgtccagc cagcagcccc gatagatatc tggggcatca 4374 0 aatcccaatt aattgcacct ttaataattg cagcgttatt gaatttccag tcgagttgac 4380 0 tgacttttcg gcctccttct tcggctagat aaacacgctc ttttgttttt ccgctcagag 4386 0 ttccaagact aatgtccgca tttatgttgt caggagtaaa cgataaagtc tcggtagaag 4392 0 caaaagagct gatcgcaata ggggttgtca ggactattcc cagaagtttc gcccgcataa 4398 0 aaggtctcca ttcaatcgtt ttaatgattg aatatgtatt ttttatatct aacttaatga 4404 0 gtcaattgta tattgtttaa ctgtttatgg tttgtttaag tttgaattat tgtttcgttt 4410 0 tattcattct ttatgggcag cttgccaagt gttgtattat tgttgtggtt taatatgctg 4416 0 gaaattttct ttttgctgat atttttatct gtctatagtt attcatttat acgcatatta 4422 0 gcaaaaaaaa tattatttta ggtatttcta cagtacattt gacacgatga ttaacctcta 4428 0 tgtagctagg tttttgtaaa gaaactgtgc gtcactgtat ccaggactgt tatgtgccaa 4434 0 ataaggaagt tgaagttacc agctcttact ctaaagctat aacgtataga aaaaatgcat 4440 0 ttgagacgtg taaaatcatt tatttaatcg caatttatgt aatggcataa tcaggtcggt 4446 0 gaaagagggg agaagaatgg ataaaagagc taaaaatcag atagtcgata gcgatattgc 4452 0 acgtttgtta ctcaagctca gaaagtctcg aaacttgact gttacagagc ttgcccaacg 4458 0 atctggtgtc agtcaggcga tgatcagcaa agttgaacga ggcacttcaa gccccagtgc 4464 0 aacaatactt agtcggttag ctaatgcact gaatattacg ctatcaaagc tttttgcaga 4470 0 gcttgagatg caacagaatt cacttgtact tttggctgac cagcaacaac attggattga 4476 0 tgaagaaaca ggcattaccc gctggtcttt gtccccagcg ggtgcatgtc cggaactaat 4482 0 aaaagttgaa atccccccta tggggcaatt gactatccct gcctctgcaa atgagcatct 4488 0 ttctggacaa actctatgga tgttaagcgg cagccttgat tttcgagtca atcatcagac 4494 0 tcatcattta caagccggtg attgtcttgc tcttaccttt gccagcgagt accaaatgag 4500 0 aaacccagat agcggccaga gttgttctta cattgtcgct ttcagccaaa aaaatccatg 4506 0 atgtaattct cctaaaatta tcatgtcaca ttgcgttata aagatgtaat agagggtagg 4512 0 gtctgccttg attgtcccgc tcggaacgtc ctgaaagttt aaagcccata tgttgataaa 4518 0 tgaaccgccc cggaaatcct ggagactaaa ctccctgaga aagaggtaaa caggatgact 4524 0 aaaaatactc gtttttcccc cgaagtccgt cagcgggcga ttcgtatggt tctggaaagt 4530 0 caggatgaat atgactcaca gtgggcggca atttgttcca ttgccccaaa gattggctgt 4536 0 acgccggaga ctctgcgtgt ctgggttcgc cagcatgagc gggataccgg gggcggtgat 4542 0 ggtgggctca ccagcgctga acgtcagcgt ctgaaagagc tggaacgtga aaatcgtgaa 4548 0 ctgcgccgca gtaacgatat ccttcgccag gcttccgctt attttgcgaa ggcggagttc 4554 0 gaccgcctct ggaaaaaatg atgccactgc tggataagct gcgtgagcag tacggggtcg 4560 0 gaccggtatg cagcgaactg catattgccc cgtcaacgta ttaccattgt cagcaacagc 4566 0 gacatcatcc ggataaacgc agtgcccgtg cgcagcacga cgactggctg aagagagaga 4572 0 tacagcgcgt atacgatgaa aatcatcagg tgtacggtgt gcgtaaagtc tggcgtcagt 4578 0 tgttacggga aggaatcagg gtggccagat gtacagtggc acgtctcatg gcggttatgg 4584 0 gacttgccgg tgttctccgg ggtaaaaagg tccgtacgac catcagccgg aaagccgttg 4590 0 ccgcaggcga ccgcgtaaac cgtcagttcg tggcagaacg acctgaccag ctgtgggtgg 4596 0 ctgattttac ttacgtcagc acatggcagg gcttcgtcta tgtggcgttt atcattgatg 4602 0 tgtttgccgg atacatcgtg gggtggcggg tctcatcgtc tatggaaacg acattcgtgc 4608 0 tggatgcgct ggagcaggcg ttgtgggccc gtcgtccgtc tggcaccatc catcacagcg 4614 0 ataaaggctc tcagtatgtg tcactagcct atacggagcg actaaaagaa gccggattac 4620 0 tggcatcaac agggagtaca ggcgactcgt atgacaacgc gatggctgag agcatcaatg 4626 0 gtctttacaa agcggaggta atacaccgta agagctggaa aaaccgtgca gaagtggaac 4632 0 tggccacact aacgtgggtg gactggtata acaatcgacg attgctggga aggctgggcc 4638 0 atactcctcc ggcagaagca gaaaaagctt attatgcttc catcggaaac gatgatctgg 4644 0 cagcctgagt tcacagataa aacactctcc aggaaacccg gggcggttca ccactgatgc 4650 0 gggtgccggg tttgagcaga cgctgaccgg aatgacagtg gggatcgaca gccgtaatga 4656 0 tattcctgag gggattgcga cgctgggcgc ttttatgggt tattcccatt cacatatcgg 4662 0 ttttgatcgt ggaggacatg gcagtgtgga cagttattct ctgggcggct atgccagttg 4668 0 ggaacatgaa agtggtttct atctggacgg tgtcgtgaag ctgaaccgtt ttgaaagtaa 4674 0 cgtagccggt aaaatgagca gcggtggagc cgccaatggc agttaccata gcaacgggct 4680 0 gggcggtcac attgaaaccg ggatgcgatt taccgatggt aactggaacc tgacgccgta 4686 0 tgcctcgtta acggggttca ccgctgataa ccccgaa 4689 7 <210> 631 <211> 381 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(60..1202) <400> 631 Met Ala Ala Ser Pro Arg Ser His Lys Ile Ser Ile Pro Asn Leu Tyr 1 5 10 15 Cys Lys Leu Asp Lys Arg Thr Gly Lys Val Tyr Trp Gln Tyr Lys His 20 25 30 Pro Leu Ser Gly Arg Phe His Ser Leu Gly Thr Asp Glu Asn Glu Ala 35 40 45 Lys Gln Val Ala Thr Glu Ala Asn Thr Ile Ile Ala Glu Gln Arg Thr 50 55 60 Arg Gln Ile Leu Ser Val Asn Glu Arg Leu Glu Arg Met Lys Gly Arg 65 70 75 80 Arg Ser Asp Ile Thr Val Thr Glu Trp Leu Asp Lys Tyr Asn Ser Ile 85 90 95 Gln Glu Asp Arg Leu Gln His Asn Glu Leu Arg Pro Asn Ser Tyr Arg 100 105 110 Gln Lys Gly Lys Pro Ile Arg Leu Phe Arg Glu His Cys Gly Met Gln 115 120 125 His Leu Lys Asp Ile Thr Ala Leu Asp Ile Ala Glu Ile Ile Asp Ala 130 135 140 Val Lys Ala Glu Gly His Asn Arg Met Ala Gln Val Val Arg Met Val 145 150 155 160 Leu Ile Asp Val Phe Lys Glu Ala Gln His Ala Gly His Val Pro Pro 165 170 175 Gly Phe Asn Pro Ala Gln Ala Thr Lys Gln Pro Arg Asn Arg Val Asn 180 185 190 Arg Gln Arg Leu Ser Leu Pro Glu Trp Gln Ala Ile Phe Asp Ser Val 195 200 205 Ser Arg Arg Gln Pro Tyr Leu Lys Cys Gly Met Leu Leu Ala Leu Val 210 215 220 Thr Gly Gln Arg Leu Ser Asp Ile Cys Asn Leu Lys Phe Ser Asp Ile 225 230 235 240 Trp Asp Asp Met Leu His Ile Thr Gln Glu Lys Thr Gly Ser Lys Leu 245 250 255 Ala Ile Pro Leu Asn Leu Lys Cys Asp Ala Leu Asn Ile Thr Leu Arg 260 265 270 Glu Val Ile Ser Gln Cys Arg Asp Ala Val Val Ser Lys Tyr Leu Val 275 280 285 His Tyr Arg His Thr Thr Ser Gln Ala Asn Arg Gly Asp Gln Val Ser 290 295 300 Ala Asn Thr Leu Thr Thr Ala Phe Lys Lys Ala Arg Glu Lys Cys Gly 305 310 315 320 Ile Lys Trp Glu Gln Gly Thr Ala Pro Thr Phe His Glu Gln Arg Ser 325 330 335 Leu Ser Glu Arg Leu Tyr Arg Glu Gln Gly Leu Asp Thr Gln Lys Leu 340 345 350 Leu Gly His Lys Ser Arg Lys Met Thr Asp Arg Tyr Asn Asp Asp Arg 355 360 365 Gly Lys Asp Trp Ile Ile Val Asp Ile Lys Thr Ala * 370 375 380 <210> 632 <211> 79 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1192..1428) <400> 632 Met Ser Arg Leu Ile Thr Leu Arg Asp Trp Ala Lys Glu Glu Phe Gly 1 5 10 15 Asp Leu Ala Pro Ser Glu Arg Val Leu Lys Lys Tyr Ala Gln Gly Lys 20 25 30 Met Met Ala Pro Pro Ala Ile Lys Val Gly Arg Tyr Trp Met Ile Asp 35 40 45 Arg Asn Ser Arg Phe Val Gly Thr Leu Ala Glu Pro Gln Leu Pro Ile 50 55 60 Asn Ala Asn Pro Lys Leu Gln Arg Ile Ile Ala Asp Gly Cys * 65 70 75 <210> 633 <211> 275 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1532..2356) <400> 633 Met Leu Arg Asn Ala Val Leu Asn Leu Ser Ile Phe His Gln Leu Leu 1 5 10 15 Val Phe Leu Ala Val Met Arg Lys Thr Tyr Gly Phe Asn Lys Lys Leu 20 25 30 Asp Trp Val Ser Asn Glu Gln Leu Ser Glu Leu Thr Gly Ile Leu Pro 35 40 45 His Lys Cys Ser Ala Ala Lys Ser Val Leu Val Lys Arg Gly Ile Phe 50 55 60 Ile Gln Ser Gly Arg Asn Thr Gly Ile Asn Asn Val Val Ser Glu Trp 65 70 75 80 Ser Thr Leu Pro Glu Ser Gly Lys Lys Asn Lys Val Tyr Leu Lys Glu 85 90 95 Val Asn Leu Pro Glu Ser Gly Lys Lys Ser Leu Pro Lys Ser Gly Lys 100 105 110 Gly Val Tyr Pro Asn Gln Val Asn Thr Lys Asp Lys Leu Thr Lys Asp 115 120 125 Asn Ile Lys Pro Phe Ser Ser Glu Asn Ser Gly Glu Ser Ser Asp Gln 130 135 140 Pro Glu Asn Asp Leu Pro Val Val Lys Pro Asp Ala Ala Ile Gln Ser 145 150 155 160 Gly Ser Lys Trp Gly Thr Ala Glu Asp Leu Thr Ala Ala Glu Trp Met 165 170 175 Phe Asp Met Val Lys Thr Ile Ala Pro Ser Ala Arg Lys Pro Asn Phe 180 185 190 Ala Gly Trp Ala Asn Asp Ile Arg Leu Met Arg Glu Arg Asp Gly Arg 195 200 205 Asn His Arg Asp Met Cys Val Leu Phe Arg Trp Ala Cys Gln Asp Asn 210 215 220 Phe Trp Ser Gly Asn Val Leu Ser Pro Ala Lys Leu Arg Asp Lys Trp 225 230 235 240 Thr Gln Leu Glu Ile Asn Arg Asn Lys Gln Gln Ala Gly Met Ile Ala 245 250 255 Ser Lys Pro Lys Leu Asp Leu Thr Asn Thr Asp Trp Ile Tyr Gly Val 260 265 270 Asp Leu * <210> 634 <211> 234 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2353..3054) <400> 634 Met Lys Asn Ile Ala Ala Gln Met Val Asn Phe Asp Arg Glu Gln Met 1 5 10 15 Arg Arg Ile Ala Asn Asn Met Pro Glu Gln Tyr Asp Glu Lys Pro Gln 20 25 30 Val Gln Gln Val Ala Gln Ile Ile Asn Gly Val Phe Ser Gln Leu Leu 35 40 45 Ala Thr Phe Pro Ala Ser Leu Ala Asn Arg Asp Gln Asn Glu Leu Asn 50 55 60 Glu Ile Arg Arg Gln Trp Val Leu Ala Phe Arg Glu Asn Gly Ile Thr 65 70 75 80 Thr Met Glu Gln Val Asn Ala Gly Met Arg Val Ala Arg Arg Gln Asn 85 90 95 Arg Pro Phe Leu Pro Ser Pro Gly Gln Phe Val Ala Trp Cys Arg Glu 100 105 110 Glu Ala Ser Val Ile Ala Gly Leu Pro Asn Val Ser Glu Leu Val Asp 115 120 125 Met Val Tyr Glu Tyr Cys Arg Lys Arg Gly Leu Tyr Pro Asp Ala Glu 130 135 140 Ser Tyr Pro Trp Lys Ser Asn Ala His Tyr Trp Leu Val Thr Asn Leu 145 150 155 160 Tyr Gln Asn Met Arg Ala Asn Ala Leu Thr Asp Ala Glu Leu Arg Arg 165 170 175 Lys Ala Ala Asp Glu Leu Thr Cys Met Thr Ala Arg Ile Asn Arg Gly 180 185 190 Glu Thr Ile Pro Glu Pro Val Lys Gln Leu Pro Val Met Gly Gly Arg 195 200 205 Pro Leu Asn Arg Ala Gln Ala Leu Ala Lys Ile Ala Glu Ile Lys Ala 210 215 220 Lys Phe Gly Leu Lys Gly Ala Ser Val * 225 230 <210> 635 <211> 101 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3051..3353) <400> 635 Met Thr Gly Lys Glu Ala Ile Ile His Tyr Leu Gly Thr His Lys Ser 1 5 10 15 Phe Cys Ala Gln Asp Val Ala Ala Val Thr Gly Ala Thr Val Thr Ser 20 25 30 Ile Asn Gln Ala Ala Ala Lys Met Ala Arg Ala Gly Ile Leu Val Val 35 40 45 Asp Gly Lys Val Trp Arg Thr Val Tyr Tyr Arg Phe Ala Thr Arg Glu 50 55 60 Glu Arg Glu Gly Lys Val Ser Thr Asn Leu Ile Phe Lys Glu Cys Arg 65 70 75 80 Gln Ser Ala Ala Met Lys Arg Val Leu Arg Val Tyr Lys Arg Thr Ser 85 90 95 Met Gly Thr Gln * 100 <210> 636 <211> 111 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3421..3753) <400> 636 Met Asn Pro Tyr Ile Tyr Leu Gly Gly Ala Ile Leu Ala Glu Val Ile 1 5 10 15 Gly Thr Thr Leu Met Lys Phe Ser Glu Gly Phe Thr Arg Leu Trp Pro 20 25 30 Ser Val Gly Thr Ile Ile Cys Tyr Cys Ala Ser Phe Trp Leu Leu Ala 35 40 45 Gln Thr Leu Ala Tyr Ile Pro Thr Gly Ile Ala Tyr Ala Ile Trp Ser 50 55 60 Gly Val Gly Ile Val Leu Ile Ser Leu Leu Ser Trp Gly Phe Phe Gly 65 70 75 80 Gln Arg Leu Asp Leu Pro Ala Val Ile Gly Met Met Leu Ile Cys Ala 85 90 95 Gly Val Leu Val Ile Asn Leu Leu Ser Arg Ser Thr Pro His * 100 105 110 <210> 637 <211> 509 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3998..5524) <400> 637 Met Lys Lys Ala Ile Ala Tyr Met Arg Phe Ser Ser Pro Gly Gln Met 1 5 10 15 Ser Gly Asp Ser Leu Asn Arg Gln Arg Arg Leu Ile Ala Glu Trp Leu 20 25 30 Lys Val Asn Ser Asp Tyr Tyr Leu Asp Thr Ile Thr Tyr Glu Asp Leu 35 40 45 Gly Leu Ser Ala Phe Lys Gly Lys His Ala Gln Ser Gly Ala Phe Ser 50 55 60 Glu Phe Leu Asp Ala Ile Glu His Gly Tyr Ile Leu Pro Gly Thr Thr 65 70 75 80 Leu Leu Val Glu Ser Leu Asp Arg Leu Ser Arg Glu Lys Val Gly Glu 85 90 95 Ala Ile Glu Arg Leu Lys Leu Ile Leu Asn His Gly Ile Asp Val Ile 100 105 110 Thr Leu Cys Asp Asn Thr Val Tyr Asn Ile Asp Ser Leu Asn Glu Pro 115 120 125 Tyr Ser Leu Ile Lys Ala Ile Leu Ile Ala Gln Arg Ala Asn Glu Glu 130 135 140 Ser Glu Ile Lys Ser Ser Arg Val Lys Leu Ser Trp Lys Lys Lys Arg 145 150 155 160 Gln Asp Ala Leu Glu Ser Gly Thr Ile Met Thr Ala Ser Cys Pro Arg 165 170 175 Trp Leu Ser Leu Asp Asp Lys Arg Thr Ala Phe Val Pro Asp Pro Asp 180 185 190 Arg Val Lys Thr Ile Glu Leu Ile Phe Lys Leu Arg Met Glu Arg Arg 195 200 205 Ser Leu Asn Ala Ile Ala Lys Tyr Leu Asn Asp His Ala Val Lys Asn 210 215 220 Phe Ser Gly Lys Glu Ser Ala Trp Gly Pro Ser Val Ile Glu Lys Leu 225 230 235 240 Leu Ala Asn Lys Ala Leu Ile Gly Ile Cys Val Pro Ser Tyr Arg Ala 245 250 255 Arg Gly Lys Gly Ile Ser Glu Ile Ala Gly Tyr Tyr Pro Arg Val Ile 260 265 270 Ser Asp Asp Leu Phe Tyr Ala Val Gln Glu Ile Arg Leu Ala Pro Phe 275 280 285 Gly Ile Ser Asn Ser Ser Lys Asn Pro Met Leu Ile Asn Leu Leu Arg 290 295 300 Thr Val Met Lys Cys Glu Ala Cys Gly Asn Thr Met Ile Val His Ala 305 310 315 320 Val Ser Gly Ser Leu His Gly Tyr Tyr Val Cys Pro Met Arg Arg Leu 325 330 335 His Arg Cys Asp Arg Pro Ser Ile Lys Arg Asp Leu Val Asp Tyr Asn 340 345 350 Ile Ile Asn Glu Leu Leu Phe Asn Cys Ser Lys Ile Gln Pro Val Glu 355 360 365 Asn Lys Lys Asp Ala Asn Glu Thr Leu Glu Leu Lys Ile Ile Glu Leu 370 375 380 Gln Met Lys Ile Asn Asn Leu Ile Val Ala Leu Ser Val Ala Pro Glu 385 390 395 400 Val Thr Ala Ile Ala Glu Lys Ile Arg Leu Leu Asp Lys Glu Leu Arg 405 410 415 Arg Ala Leu Val Ser Leu Lys Thr Leu Lys Ser Lys Gly Val Asn Ser 420 425 430 Phe Ser Asp Phe Tyr Ala Ile Asp Leu Thr Ser Lys Asn Gly Arg Glu 435 440 445 Leu Cys Arg Thr Leu Ala Tyr Lys Ile Phe Glu Lys Ile Ile Ile Asn 450 455 460 Thr Asp Asn Lys Thr Cys Asp Ile Tyr Phe Met Asn Gly Ile Val Phe 465 470 475 480 Lys His Tyr Pro Leu Met Lys Val Ile Ser Ala Gln Gln Ala Ile Ser 485 490 495 Ala Leu Lys Tyr Met Val Asp Gly Glu Val Tyr Phe * 500 505 <210> 638 <211> 152 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6026..6481) <400> 638 Val Asn Leu Pro Gln Asp Gly Ile Lys Leu His Arg Gly Asn Phe Thr 1 5 10 15 Ala Val Gly Gln Gln Ile Gln Thr Tyr Leu Glu Asp Gly Lys Cys Phe 20 25 30 Arg Met Val Leu Lys Pro Trp Arg Glu Arg Arg Ser Leu Ser Gln Asn 35 40 45 Ala Leu Ser His Met Trp Tyr Ser Glu Ile Ser Glu Tyr Leu Ile Ser 50 55 60 Arg Gly Lys Ser Phe Ala Thr Ser Ala Trp Val Lys Asp Ala Leu Lys 65 70 75 80 His Thr Tyr Leu Gly Tyr Glu Thr Lys Asp Leu Val Asp Val Val Thr 85 90 95 Gly Glu Ile Thr Thr Ile Gln Ser Leu Arg His Thr Ser Asp Leu Gly 100 105 110 Thr Gly Glu Met Tyr Val Phe Leu Cys Lys Val Glu Ala Trp Ala Met 115 120 125 Asn Ile Gly Cys His Leu Thr Ile Pro Gln Ser Cys Glu Phe Gln Leu 130 135 140 Leu Arg Asp Lys Gln Glu Ala * 145 150 <210> 639 <211> 57 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6481..6651) <400> 639 Met Ala Thr Pro Leu Ile Arg Val Met Asn Gly His Ile Tyr Lys Val 1 5 10 15 Pro Asn Arg Arg Lys Arg Lys Pro Glu Leu Lys Pro Ser Glu Ile Pro 20 25 30 Thr Leu Leu Gly Tyr Thr Ala Ser Leu Val Asp Lys Lys Trp Leu Arg 35 40 45 Leu Ala Ala Arg Arg Asn His Gly * 50 55 <210> 640 <211> 97 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6644..6934) <400> 640 Met Ala Asp Leu Arg Lys Ala Ala Arg Ser Arg Glu Cys Gln Val Arg 1 5 10 15 Ile Pro Gly Val Cys Asn Gly Asn Pro Glu Thr Ser Val Leu Ala His 20 25 30 Ile Arg Leu Thr Gly Leu Cys Gly Thr Gly Thr Lys Pro Pro Asp Leu 35 40 45 Ile Ala Thr Ile Ala Cys Ser Ala Cys His Asp Glu Ile Asp Arg Arg 50 55 60 Thr His Phe Val Asp Ala Ala Tyr Ala Lys Glu Cys Ala Leu Glu Gly 65 70 75 80 Met Ala Arg Thr Gln Val Ile Trp Leu Lys Glu Gly Val Ile Lys Ala 85 90 95 * <210> 641 <211> 121 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6931..7293) <400> 641 Val Asn Thr Tyr Ser Ile Thr Leu Pro Trp Pro Pro Ser Asn Asn Arg 1 5 10 15 Tyr Tyr Arg His Asn Arg Gly Arg Thr His Ile Ser Ala Glu Gly Gln 20 25 30 Ala Tyr Arg Asp Asn Val Ala Arg Ile Ile Lys Gly Ser Met Leu Asp 35 40 45 Ile Gly Leu Ala Met Pro Val Lys Ile Arg Ile Glu Cys His Met Pro 50 55 60 Asp Arg Arg Arg Arg Asp Leu Asp Asn Leu Gln Lys Ala Ala Phe Asp 65 70 75 80 Ala Leu Thr Lys Ala Gly Phe Trp Leu Asp Asp Ala Gln Val Val Asp 85 90 95 Tyr Arg Val Val Lys Met Pro Val Thr Lys Gly Gly Lys Leu Glu Leu 100 105 110 Thr Ile Thr Glu Leu Gly Asn Glu * 115 120 <210> 642 <211> 230 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7427..8116) <400> 642 Met Asn Thr Gln Tyr Leu Gln Tyr Val Arg Glu Gln Leu Ile Val Ala 1 5 10 15 Thr Ala Asp Leu Ser Gly Ala Thr Lys Gly Gln Leu Glu Ala Trp Leu 20 25 30 Glu His Ala Gln Phe Asp Thr Gly Thr Tyr Lys Arg Lys Lys Pro Arg 35 40 45 Ile Leu Asp Glu Val Thr Gly Arg Met Ile Thr Leu Asp Asn Pro Pro 50 55 60 Ile Ser Gly Lys Gln Ser Tyr Ala Lys Gly Ser Ser Ile Ala Leu Val 65 70 75 80 Ser Gln Val Glu Phe Ser Thr Ser Ser Trp Arg Arg Ala Val Leu Ser 85 90 95 Leu Glu Glu His Gln Lys Ala Trp Leu Leu Trp Ser Tyr Ser Glu Ser 100 105 110 Val Arg Trp Glu His Gln Val Thr Ile Thr Gln Trp Ala Trp Ser Glu 115 120 125 Phe Lys Thr Leu Leu Gly Thr Arg Lys Ile Ala Gly Lys Thr Leu Glu 130 135 140 Arg Leu Lys Lys Leu Ile Trp Leu Ala Ala Gln Asp Val Lys Asn Glu 145 150 155 160 Leu Ala Gly Arg Lys Thr Tyr Glu Tyr Gln Glu Leu Ala Ser Leu Val 165 170 175 Gly Val Thr Ser Lys Asn Trp Ser Glu Thr Phe Thr Glu Arg Trp Val 180 185 190 Ala Met Lys His Ile Phe Leu Gln Leu Asp Ser Gln Ala Leu Leu Leu 195 200 205 Leu Thr Lys Thr Arg Ser Lys Gln Lys Thr Thr Phe Ser Gln Gln Asp 210 215 220 Ile Ala Lys Leu Asp * 225 <210> 643 <211> 106 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8426..8743) <400> 643 Leu Ala Ile His Met His Glu Lys Glu Ser Leu Ala Gly Ala Phe Trp 1 5 10 15 Leu Val Leu Leu Ile Ile Ala Gly Trp Gly Gly Leu Val Arg Tyr Leu 20 25 30 Ile Asp Val Lys Gln Ser Lys Ala Thr Trp Ser Trp Ile Asn Ala Leu 35 40 45 Ala Gln Ile Val Val Ser Gly Phe Thr Gly Val Ile Gly Gly Leu Ile 50 55 60 Ser Ile Glu Ser Gly Phe Ser Ile Tyr Met Ile Leu Ala Thr Ala Gly 65 70 75 80 Ile Ser Gly Ala Met Gly Ser Val Ala Leu Thr Tyr Phe Trp Glu Arg 85 90 95 Leu Thr Gly Val Lys Asn Ala Lys Ser * 100 105 <210> 644 <211> 159 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8730..9206) <400> 644 Met Gln Asn Leu Asn Pro Gln Arg Lys Ala Phe Leu Asp Met Leu Ala 1 5 10 15 Trp Ser Glu Gly Thr Asp Asn Gly Arg Gln Pro Thr Arg Asn His Gly 20 25 30 Tyr Asp Val Ile Val Gly Gly Glu Leu Phe Thr Asp Tyr Ser Asp His 35 40 45 Pro Arg Lys Leu Val Thr Leu His Pro Lys Leu Lys Ser Thr Ala Ala 50 55 60 Gly Arg Tyr Gln Leu Leu Ser Arg Trp Trp Asp Ala Tyr Arg Lys Gln 65 70 75 80 Leu Gly Leu Lys Asp Phe Ser Pro Lys Ser Gln Asp Ala Val Ala Leu 85 90 95 Gln Gln Ile Lys Glu Arg Gly Ala Leu Pro Met Ile Asp Arg Gly Asp 100 105 110 Ile Arg Gln Ala Ile Asp Arg Cys Ser Asn Ile Trp Ala Ser Leu Pro 115 120 125 Gly Ala Gly Tyr Gly Gln Phe Glu His Lys Ala Asp Ser Leu Ile Ala 130 135 140 Lys Phe Lys Glu Ala Gly Gly Thr Val Arg Glu Ser Glu Val * 145 150 155 <210> 645 <211> 154 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9203..9664) <400> 645 Met Ser Arg Ile Thr Ala Ile Ile Ser Ala Leu Leu Ile Cys Ile Ile 1 5 10 15 Val Cys Leu Ser Trp Ala Val Asn His Tyr Arg Asp Asn Ala Ile Thr 20 25 30 Tyr Lys Ala Gln Arg Asp Lys Asn Ala Arg Glu Leu Lys Leu Ala Asn 35 40 45 Val Ala Ile Thr Asp Met Gln Met Arg Gln Arg Asp Val Ala Ala Leu 50 55 60 Asp Ala Lys Tyr Thr Lys Glu Leu Ala Asp Ala Lys Ala Glu Asn Asp 65 70 75 80 Ala Leu His Asp Asp Val Ala Ala Gly Arg Arg Arg Leu His Ile Lys 85 90 95 Ala Val Cys Gln Ser Val Arg Glu Ala Thr Thr Ala Ser Gly Val Asp 100 105 110 Asn Ala Ala Ser Pro Arg Leu Ala Asp Thr Ala Glu Arg Asp Tyr Phe 115 120 125 Thr Leu Arg Glu Arg Leu Ile Thr Met Gln Lys Gln Leu Glu Gly Thr 130 135 140 Gln Lys Tyr Ile Asn Glu Gln Cys Arg * 145 150 <210> 646 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9423..9605) <400> 646 Met Arg Lys Leu Lys Met Met Leu Cys Met Met Met Leu Pro Leu Val 1 5 10 15 Val Val Gly Cys Thr Ser Lys Gln Ser Val Ser Gln Cys Val Lys Pro 20 25 30 Pro Pro Pro Pro Ala Trp Ile Met Gln Pro Pro Pro Asp Trp Gln Thr 35 40 45 Pro Leu Asn Gly Ile Ile Ser Pro Ser Glu Arg Gly * 50 55 60 <210> 647 <211> 98 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9696..9989) <400> 647 Met Lys Lys Met Leu Leu Ala Thr Ala Leu Ala Leu Leu Ile Thr Gly 1 5 10 15 Cys Ala Gln Gln Thr Phe Thr Val Gln Asn Lys Pro Ala Ala Val Thr 20 25 30 Pro Lys Glu Thr Ile Thr His His Phe Phe Val Ser Gly Ile Gly Gln 35 40 45 Lys Lys Thr Val Asp Ala Ala Lys Ile Cys Gly Gly Ala Glu Asn Val 50 55 60 Val Lys Thr Glu Thr Gln Gln Thr Phe Val Asn Gly Leu Leu Gly Phe 65 70 75 80 Ile Thr Leu Gly Ile Tyr Thr Pro Leu Glu Ala Arg Val Tyr Cys Ser 85 90 95 Gln * <210> 648 <211> 151 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10281..10733) <400> 648 Met Gln Thr Thr Arg Pro Arg Ile Thr Trp Lys Val Leu Pro Met Ala 1 5 10 15 Gln Val Ala Ile Phe Lys Glu Ile Phe Asp Gln Val Arg Lys Asp Leu 20 25 30 Asn Cys Glu Leu Phe Tyr Ser Glu Leu Lys Arg His Asn Val Ser His 35 40 45 Tyr Ile Tyr Tyr Leu Ala Thr Asp Asn Ile His Ile Val Leu Glu Asn 50 55 60 Asp Asn Thr Val Leu Ile Lys Gly Leu Lys Lys Val Val Asn Val Lys 65 70 75 80 Phe Ser Arg Asn Thr His Leu Ile Glu Thr Ser Tyr Asp Arg Leu Lys 85 90 95 Ser Arg Glu Ile Thr Phe Gln Gln Tyr Arg Glu Asn Leu Ala Lys Ala 100 105 110 Gly Val Phe Arg Trp Val Thr Asn Ile His Glu His Lys Arg Tyr Tyr 115 120 125 Tyr Ala Phe Asp Asn Ser Leu Leu Phe Thr Glu Ser Ile Gln Asn Thr 130 135 140 Thr Gln Ile Phe Pro Arg * 145 150 <210> 649 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10977..11183) <400> 649 Met Asn Lys Glu Gln Ser Ala Asp Asp Pro Ser Val Asp Leu Ile Arg 1 5 10 15 Val Lys Asn Met Leu Asn Ser Thr Ile Ser Met Ser Tyr Pro Asp Val 20 25 30 Val Ile Ala Cys Ile Glu His Lys Val Ser Leu Glu Ala Phe Arg Ala 35 40 45 Ile Glu Ala Ala Leu Val Lys His Asp Asn Asn Met Lys Asp Tyr Ser 50 55 60 Leu Val Val Asp * 65 <210> 650 <211> 65 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11348..11542) <400> 650 Met Ser Thr Lys Asn Arg Thr Arg Arg Thr Thr Thr Arg Asn Ile Arg 1 5 10 15 Phe Pro Asn Gln Met Ile Glu Gln Ile Asn Ile Ala Leu Asp Gln Lys 20 25 30 Gly Ser Gly Asn Phe Ser Ala Trp Val Ile Glu Ala Cys Arg Arg Arg 35 40 45 Leu Thr Ser Glu Lys Arg Ala Tyr Thr Ser Ile Lys Ser Asp Glu Glu 50 55 60 * <210> 651 <211> 182 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11931..12476) <400> 651 Met Glu Val Asn Lys Lys Gln Leu Ala Asp Ile Phe Gly Ala Ser Ile 1 5 10 15 Arg Thr Ile Gln Asn Trp Gln Glu Gln Gly Met Pro Val Leu Arg Gly 20 25 30 Gly Gly Lys Gly Asn Glu Val Leu Tyr Asp Ser Ala Ala Ala Ile Lys 35 40 45 Trp Tyr Ala Glu Arg Asp Ala Glu Ile Glu Asn Glu Lys Leu Arg Arg 50 55 60 Glu Val Glu Glu Leu Arg Gln Asp Ser Glu Thr Asp Leu Gln Pro Gly 65 70 75 80 Thr Ile Glu Tyr Glu Arg His Arg Leu Thr Arg Ala Gln Ala Asp Ala 85 90 95 Gln Glu Leu Lys Asn Ala Arg Asp Ser Ala Glu Val Val Glu Thr Ala 100 105 110 Phe Cys Thr Phe Val Leu Ser Arg Ile Ala Gly Glu Ile Ala Ser Ile 115 120 125 Leu Asp Gly Ile Pro Leu Ser Val Gln Arg Arg Phe Pro Glu Leu Glu 130 135 140 Asn Arg His Val Asp Phe Leu Lys Arg Asp Ile Ile Lys Ala Met Asn 145 150 155 160 Lys Ala Ala Ala Leu Asp Glu Leu Ile Pro Gly Leu Leu Ser Glu Tyr 165 170 175 Ile Glu Gln Ser Gly * 180 <210> 652 <211> 642 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12451..14376) <400> 652 Val Asn Ile Ser Asn Ser Gln Val Asn Arg Leu Arg His Phe Val Arg 1 5 10 15 Ala Gly Leu Arg Ser Leu Phe Arg Pro Glu Pro Gln Thr Ala Val Glu 20 25 30 Trp Ala Asp Ala Ser Tyr Tyr Leu Pro Lys Glu Ser Ala Tyr Gln Glu 35 40 45 Gly Arg Trp Glu Thr Leu Pro Phe Gln Arg Ala Ile Met Asn Ala Met 50 55 60 Gly Ser Asp Tyr Ile Arg Glu Val Asn Val Val Lys Ser Ala Arg Val 65 70 75 80 Gly Tyr Ser Lys Met Leu Leu Gly Val Tyr Ala Tyr Phe Ile Glu His 85 90 95 Lys Gln Arg Asn Thr Leu Ile Trp Leu Pro Thr Asp Gly Asp Ala Glu 100 105 110 Asn Phe Met Lys Thr His Val Glu Pro Thr Ile Arg Asp Ile Pro Ser 115 120 125 Leu Leu Ala Leu Ala Pro Trp Tyr Gly Lys Lys His Arg Asp Asn Thr 130 135 140 Leu Thr Met Lys Arg Phe Thr Asn Gly Arg Gly Phe Trp Cys Leu Gly 145 150 155 160 Gly Lys Ala Ala Lys Asn Tyr Arg Glu Lys Ser Val Asp Val Ala Gly 165 170 175 Tyr Asp Glu Leu Ala Ala Phe Asp Glu Asp Ile Glu Gln Glu Gly Ser 180 185 190 Pro Thr Phe Leu Gly Asp Lys Arg Ile Glu Gly Ser Val Trp Pro Lys 195 200 205 Ser Ile Arg Gly Ser Thr Pro Lys Val Arg Gly Thr Cys Gln Ile Glu 210 215 220 Arg Ala Ala Ser Glu Ser Pro His Phe Met Arg Phe His Val Ala Cys 225 230 235 240 Pro His Cys Gly Glu Glu Gln Tyr Leu Lys Phe Gly Asp Lys Glu Thr 245 250 255 Pro Phe Gly Leu Lys Trp Thr Pro Asp Asp Pro Ser Ser Val Phe Tyr 260 265 270 Leu Cys Glu His Asn Ala Cys Val Ile Arg Gln Gln Glu Leu Asp Phe 275 280 285 Thr Asp Ala Arg Tyr Ile Cys Glu Lys Thr Gly Ile Trp Thr Arg Asp 290 295 300 Gly Ile Leu Trp Phe Ser Ser Ser Gly Glu Glu Ile Glu Pro Pro Asp 305 310 315 320 Ser Val Thr Phe His Ile Trp Thr Ala Tyr Ser Pro Phe Thr Thr Trp 325 330 335 Val Gln Ile Val Lys Asp Trp Met Lys Thr Lys Gly Asp Thr Gly Lys 340 345 350 Arg Lys Thr Phe Val Asn Thr Thr Leu Gly Glu Thr Trp Glu Ala Lys 355 360 365 Ile Gly Glu Arg Pro Asp Ala Glu Val Met Ala Glu Arg Lys Glu His 370 375 380 Tyr Ser Ala Ser Val Pro Asp Arg Val Ala Tyr Leu Thr Ala Gly Ile 385 390 395 400 Asp Ser Gln Leu Asp Arg Tyr Glu Met Arg Val Trp Gly Trp Gly Pro 405 410 415 Gly Glu Glu Ser Trp Leu Ile Asp Arg Gln Ile Ile Met Gly Arg His 420 425 430 Asp Asp Glu Gln Thr Leu Leu Arg Val Asp Glu Ala Ile Asn Lys Thr 435 440 445 Tyr Thr Arg Arg Asn Gly Ala Glu Met Ser Val Ser Arg Ile Cys Trp 450 455 460 Asp Thr Gly Gly Ile Asp Pro Thr Ile Val Tyr Glu Arg Ser Lys Lys 465 470 475 480 His Gly Leu Phe Arg Val Ile Pro Ile Lys Gly Ala Ser Val Tyr Gly 485 490 495 Lys Pro Val Ala Ser Met Pro Arg Lys Arg Asn Lys Asn Gly Val Tyr 500 505 510 Leu Thr Glu Ile Gly Thr Asp Thr Ala Lys Glu Gln Ile Tyr Asn Arg 515 520 525 Phe Thr Leu Thr Pro Glu Gly Asp Glu Pro Leu Pro Gly Ala Val His 530 535 540 Phe Pro Asn Asn Pro Asp Ile Phe Asp Leu Thr Glu Ala Gln Gln Leu 545 550 555 560 Thr Ala Glu Glu Gln Val Glu Lys Trp Val Asp Gly Arg Lys Lys Ile 565 570 575 Leu Trp Asp Ser Lys Lys Arg Arg Asn Glu Ala Leu Asp Cys Phe Val 580 585 590 Tyr Ala Leu Ala Ala Leu Arg Ile Ser Ile Ser Arg Trp Gln Leu Asp 595 600 605 Leu Ser Ala Leu Leu Ala Ser Leu Gln Glu Glu Asp Gly Ala Ala Thr 610 615 620 Asn Lys Lys Thr Leu Ala Glu Tyr Ala Arg Ala Leu Ser Gly Glu Asp 625 630 635 640 Glu * <210> 653 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14373..14579) <400> 653 Met Thr Arg Gln Glu Glu Leu Ala Ala Ala Arg Ala Ala Leu His Asp 1 5 10 15 Leu Met Thr Gly Lys Arg Val Ala Thr Val Gln Lys Asp Gly Arg Arg 20 25 30 Val Glu Phe Thr Thr Thr Ser Val Ser Asp Leu Lys Lys Tyr Ile Ala 35 40 45 Glu Leu Glu Val Gln Thr Gly Met Thr Gln Arg Arg Arg Gly Pro Ala 50 55 60 Gly Phe Tyr Val * 65 <210> 654 <211> 534 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14576..16177) <400> 654 Met Lys Met Ser Thr Ile Pro Thr Leu Leu Gly Pro Asp Gly Met Thr 1 5 10 15 Ser Leu Arg Glu Tyr Ala Gly Tyr His Gly Gly Gly Ser Gly Phe Gly 20 25 30 Gly Gln Leu Arg Ala Trp Asn Pro Pro Gly Glu Ser Val Asp Ala Ala 35 40 45 Leu Leu Pro Asn Phe Thr Arg Gly Asn Ala Arg Ala Asp Asp Leu Val 50 55 60 Arg Asn Asn Gly Tyr Ala Ala Asn Ala Ile Gln Leu His Gln Asp His 65 70 75 80 Ile Val Gly Ser Phe Phe Arg Leu Ser His Arg Pro Ser Trp Arg Tyr 85 90 95 Leu Gly Ile Gly Glu Glu Glu Ala Arg Ala Phe Ser Arg Glu Val Glu 100 105 110 Ala Ala Trp Lys Glu Phe Ala Glu Asp Asp Cys Cys Cys Ile Asp Val 115 120 125 Glu Arg Lys Arg Thr Phe Thr Met Met Ile Arg Glu Gly Val Ala Met 130 135 140 His Ala Phe Asn Gly Glu Leu Phe Val Gln Ala Thr Trp Asp Thr Arg 145 150 155 160 Pro Ser Arg Leu Phe Arg Thr Gln Phe Arg Met Val Ser Pro Lys Arg 165 170 175 Ile Ser Asn Pro Asn Asn Thr Ser Asp Ser Arg Asn Cys Arg Ala Gly 180 185 190 Val Gln Ile Asn Asp Ser Gly Ala Ala Leu Gly Tyr Tyr Val Ser Glu 195 200 205 Asp Gly Tyr Pro Gly Trp Met Pro Gln Lys Trp Thr Trp Ile Pro Arg 210 215 220 Glu Leu Pro Gly Gly Arg Ala Ser Phe Ile His Val Phe Glu Pro Val 225 230 235 240 Glu Asp Gly Gln Thr Arg Gly Ala Asn Val Phe Tyr Ser Val Met Glu 245 250 255 Gln Met Lys Met Leu Asp Thr Leu Gln Asn Thr Gln Leu Gln Ser Ala 260 265 270 Ile Val Lys Ala Met Tyr Ala Ala Thr Ile Glu Ser Glu Leu Asp Thr 275 280 285 Gln Ser Ala Met Asp Phe Ile Leu Gly Ala Asn Ser Gln Glu Gln Arg 290 295 300 Glu Arg Leu Thr Gly Trp Ile Gly Glu Ile Ala Ala Tyr Tyr Ala Ala 305 310 315 320 Ala Pro Val Arg Leu Gly Gly Ala Lys Val Pro His Leu Met Pro Gly 325 330 335 Asp Ser Leu Asn Leu Gln Thr Ala Gln Asp Thr Asp Asn Gly Tyr Ser 340 345 350 Val Phe Glu Gln Ser Leu Leu Arg Tyr Ile Ala Ala Gly Leu Gly Val 355 360 365 Ser Tyr Glu Gln Leu Ser Arg Asn Tyr Ala Gln Met Ser Tyr Ser Thr 370 375 380 Ala Arg Ala Ser Ala Asn Glu Ser Trp Ala Tyr Phe Met Gly Arg Arg 385 390 395 400 Lys Phe Val Ala Ser Arg Gln Ala Ser Gln Met Phe Leu Cys Trp Leu 405 410 415 Glu Glu Ala Ile Val Arg Arg Val Val Thr Leu Pro Ser Lys Ala Arg 420 425 430 Phe Ser Phe Gln Glu Ala Arg Ser Ala Trp Gly Asn Cys Asp Trp Ile 435 440 445 Gly Ser Gly Arg Met Ala Ile Asp Gly Leu Lys Glu Val Gln Glu Ala 450 455 460 Val Met Leu Ile Glu Ala Gly Leu Ser Thr Tyr Glu Lys Glu Cys Ala 465 470 475 480 Lys Arg Gly Asp Asp Tyr Gln Glu Ile Phe Ala Gln Gln Val Arg Glu 485 490 495 Thr Met Glu Arg Arg Ala Ala Gly Leu Lys Pro Pro Ala Trp Ala Ala 500 505 510 Ala Ala Phe Glu Ser Gly Leu Arg Gln Ser Thr Glu Glu Glu Lys Ser 515 520 525 Asp Ser Arg Ala Ala * 530 <210> 655 <211> 440 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16158..17477) <400> 655 Val Thr Ala Glu Leu Arg Asn Leu Pro His Ile Ala Ser Met Ala Phe 1 5 10 15 Asn Glu Pro Leu Met Leu Glu Pro Ala Tyr Ala Arg Val Phe Phe Cys 20 25 30 Ala Leu Ala Gly Gln Leu Gly Ile Ser Arg Leu Thr Asp Ala Val Ser 35 40 45 Gly Asp Ser Leu Thr Ala Gly Glu Ala Pro Ala Ala Leu Ala Leu Ser 50 55 60 Gly Asp Asp Asp Gly Pro Arg Gln Ala Arg Ser Tyr Gln Val Met Asn 65 70 75 80 Gly Ile Ala Val Leu Pro Val Ser Gly Thr Leu Val Ser Arg Thr Arg 85 90 95 Ala Leu Gln Pro Tyr Ser Gly Met Thr Gly Tyr Asn Gly Ile Ile Ala 100 105 110 Arg Leu Gln Gln Ala Ala Ser Asp Pro Met Val Asp Gly Ile Leu Leu 115 120 125 Asp Met Asp Thr Pro Gly Gly Met Val Ala Gly Ala Phe Asp Cys Ala 130 135 140 Asp Ile Ile Ala Arg Val Arg Asp Ile Lys Pro Val Trp Ala Leu Ala 145 150 155 160 Asn Asp Met Asn Cys Ser Ala Gly Gln Leu Leu Ala Ser Ala Ala Ser 165 170 175 Arg Arg Leu Val Thr Gln Thr Ala Arg Thr Gly Ser Ile Gly Val Met 180 185 190 Met Ala His Ser Asn Tyr Gly Ala Ala Leu Glu Lys Gln Gly Val Glu 195 200 205 Ile Thr Leu Ile Tyr Ser Gly Ser His Lys Val Asp Gly Asn Pro Tyr 210 215 220 Ser His Leu Pro Gly Asp Val Arg Glu Thr Leu Gln Ser Arg Met Asp 225 230 235 240 Ala Thr Arg Arg Met Phe Ala Gln Lys Val Ser Ala Tyr Thr Gly Leu 245 250 255 Ser Val Gln Ala Val Leu Asp Thr Glu Ala Ala Val Tyr Ser Gly Gln 260 265 270 Glu Ala Ile Asp Ala Gly Leu Ala Asp Glu Leu Val Asn Ser Thr Asp 275 280 285 Ala Ile Thr Val Met Arg Asp Ala Leu Asp Ala Arg Lys Ser Arg Leu 290 295 300 Ser Gly Gly Arg Met Thr Lys Glu Thr Gln Ser Thr Thr Val Ser Ala 305 310 315 320 Thr Ala Ser Gln Ala Asp Val Thr Gly Val Val Pro Ala Thr Glu Gly 325 330 335 Glu Asn Ala Ser Ala Ala Gln Pro Asp Val Asn Ala Gln Ile Thr Ala 340 345 350 Ala Val Ala Ala Glu Asn Ser Arg Ile Met Gly Ile Leu Asn Cys Glu 355 360 365 Glu Ala His Gly Arg Glu Glu Gln Ala Arg Val Leu Ala Glu Thr Pro 370 375 380 Gly Met Thr Val Glu Thr Ala Arg Arg Ile Leu Ala Ala Ala Pro Gln 385 390 395 400 Ser Ala Gln Ala Arg Ser Asp Thr Ala Leu Asp Arg Leu Met Gln Gly 405 410 415 Ala Pro Ala Pro Leu Ala Ala Gly Asn Pro Ala Ser Asp Ala Val Asn 420 425 430 Asp Leu Leu Asn Thr Pro Val * 435 <210> 656 <211> 111 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17487..17819) <400> 656 Met Thr Ser Lys Glu Thr Phe Thr His Tyr Gln Pro Leu Gly Asn Ser 1 5 10 15 Asp Pro Ala His Thr Ala Thr Ala Pro Gly Gly Leu Ser Ala Lys Ala 20 25 30 Pro Ala Met Thr Pro Leu Met Leu Asp Thr Ser Ser Arg Lys Leu Val 35 40 45 Ala Trp Asp Gly Thr Thr Asp Gly Ala Ala Val Gly Ile Leu Ala Val 50 55 60 Ala Ala Asp Gln Thr Ser Thr Thr Leu Thr Phe Tyr Lys Ser Gly Thr 65 70 75 80 Phe Arg Tyr Glu Asp Val Leu Trp Pro Glu Ala Ala Ser Asp Glu Thr 85 90 95 Lys Lys Arg Thr Ala Phe Ala Gly Thr Ala Ile Ser Ile Val * 100 105 110 <210> 657 <211> 342 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17875..18900) <400> 657 Met Ser Met Tyr Thr Thr Ala Gln Leu Leu Ala Ala Asn Glu Gln Lys 1 5 10 15 Phe Lys Phe Asp Pro Leu Phe Leu Arg Leu Phe Phe Arg Glu Ser Tyr 20 25 30 Pro Phe Thr Thr Glu Lys Val Tyr Leu Ser Gln Ile Pro Gly Leu Val 35 40 45 Asn Met Ala Leu Tyr Val Ser Pro Ile Val Ser Gly Glu Val Ile Arg 50 55 60 Ser Arg Gly Gly Ser Thr Ser Glu Phe Thr Pro Gly Tyr Val Lys Pro 65 70 75 80 Lys His Glu Val Asn Pro Gln Met Thr Leu Arg Arg Leu Pro Asp Glu 85 90 95 Asp Pro Gln Asn Leu Ala Asp Pro Ala Tyr Arg Arg Arg Arg Ile Ile 100 105 110 Met Gln Asn Met Arg Asp Glu Glu Leu Ala Ile Ala Gln Val Glu Glu 115 120 125 Met Gln Ala Val Ser Ala Val Leu Lys Gly Lys Tyr Thr Met Thr Gly 130 135 140 Glu Ala Phe Asp Pro Val Glu Val Asp Met Gly Arg Ser Ala Ala Asn 145 150 155 160 Asn Ile Thr Gln Ser Gly Gly Thr Glu Trp Ser Lys Arg Asp Lys Ser 165 170 175 Thr Tyr Asp Pro Thr Asp Asp Ile Glu Ala Tyr Ala Leu Asn Ala Ser 180 185 190 Gly Val Val Asn Ile Ile Val Phe Asp Pro Lys Gly Trp Ala Leu Phe 195 200 205 Arg Ser Phe Lys Ala Val Arg Glu Lys Leu Asp Thr Arg Arg Gly Ser 210 215 220 His Ser Glu Leu Glu Thr Ala Val Lys Asp Leu Gly Lys Ala Val Ser 225 230 235 240 Tyr Lys Gly Met Tyr Gly Asp Val Ala Ile Val Val Tyr Ser Gly Gln 245 250 255 Tyr Val Glu Asn Gly Val Lys Lys Asn Phe Leu Pro Asp Asn Thr Met 260 265 270 Val Leu Gly Asn Thr Gln Ala Arg Gly Leu Arg Thr Tyr Gly Cys Ile 275 280 285 Gln Asp Ala Asp Ala Gln Arg Glu Gly Ile Asn Ala Ser Ala Arg Tyr 290 295 300 Pro Lys Asn Trp Val Thr Thr Gly Asp Pro Ala Arg Glu Phe Thr Met 305 310 315 320 Ile Gln Ser Ala Pro Leu Met Leu Leu Ala Asp Pro Asp Glu Phe Val 325 330 335 Ser Val Gln Leu Ala * 340 <210> 658 <211> 133 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18942..19340) <400> 658 Met Thr Lys Asp Glu Leu Ile Ala Arg Leu Arg Ser Leu Gly Glu Gln 1 5 10 15 Leu Asn Arg Asp Val Ser Leu Thr Gly Thr Lys Glu Glu Leu Ala Leu 20 25 30 Arg Val Ala Glu Leu Glu Glu Glu Leu Asp Asp Thr Asp Glu Thr Ala 35 40 45 Gly Gln Asp Thr Pro Leu Ser Arg Glu Asn Val Leu Thr Gly His Glu 50 55 60 Asn Glu Val Gly Ser Ala Gln Pro Asp Thr Val Ile Leu Asp Thr Ser 65 70 75 80 Glu Leu Val Thr Val Val Ala Leu Val Lys Leu His Thr Asp Ala Leu 85 90 95 His Val Thr Arg Asp Glu Pro Val Ala Phe Val Leu Pro Gly Thr Ala 100 105 110 Phe Arg Val Ser Ala Gly Val Ala Ala Glu Met Thr Glu Arg Gly Leu 115 120 125 Ala Arg Met Gln * 130 <210> 659 <211> 118 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19352..19705) <400> 659 Val Ala Asp Phe Asp Asn Leu Phe Asp Ala Ala Ile Ala Arg Ala Asp 1 5 10 15 Glu Thr Ile Arg Gly Tyr Met Gly Thr Ser Ala Thr Met Thr Ser Gly 20 25 30 Glu Arg Ser Gly Ala Val Ile Arg Gly Val Phe Asp Asp Pro Glu Asn 35 40 45 Ile Ser Tyr Ala Gly Gln Gly Val Arg Val Glu Gly Ser Ser Pro Ser 50 55 60 Leu Phe Val Arg Thr Asp Asp Val Arg Gln Leu Arg Arg Gly Asp Thr 65 70 75 80 Leu Thr Ile Gly Glu Glu Asn Phe Trp Ile Asp Arg Ile Ser Thr Asp 85 90 95 Asp Gly Gly Ser Cys His Leu Trp Leu Gly Arg Gly Val Pro Pro Ala 100 105 110 Val Asn Arg Arg Arg * 115 <210> 660 <211> 193 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19717..20295) <400> 660 Met Ala Ile Lys Gly Leu Glu Gln Ala Val Glu Asn Leu Ser Arg Ile 1 5 10 15 Ser Lys Thr Ala Val Pro Gly Ala Ser Ala Met Ala Ile Asn Arg Val 20 25 30 Ala Ser Ser Ala Ile Ser Gln Ser Ala Ser Gln Val Ala Arg Glu Thr 35 40 45 Arg Val Arg Arg Lys Leu Val Lys Glu Arg Ala Arg Leu Lys Arg Ala 50 55 60 Thr Val Lys Asn Pro Gln Ala Arg Ile Lys Val Asn Arg Gly Asp Leu 65 70 75 80 Pro Val Ile Lys Leu Gly Asn Ala Arg Val Val Leu Ser Arg Arg Arg 85 90 95 Arg Arg Lys Lys Gly Gln Arg Ser Ser Leu Lys Gly Gly Gly Ser Val 100 105 110 Leu Val Val Gly Asn Arg Arg Ile Pro Gly Ala Phe Ile Gln Gln Leu 115 120 125 Lys Asn Gly Arg Trp His Val Met Gln Arg Val Ala Gly Lys Asn Arg 130 135 140 Tyr Pro Ile Asp Val Val Lys Ile Pro Met Ala Val Pro Leu Thr Thr 145 150 155 160 Ala Phe Lys Gln Asn Ile Glu Arg Ile Arg Arg Glu Arg Leu Pro Lys 165 170 175 Glu Leu Gly Tyr Ala Leu Gln His Gln Leu Arg Met Val Ile Lys Arg 180 185 190 * <210> 661 <211> 132 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20292..20687) <400> 661 Met Lys His Thr Glu Leu Arg Ala Ala Val Leu Asp Ala Leu Glu Lys 1 5 10 15 His Asp Thr Gly Ala Thr Phe Phe Asp Gly Arg Pro Ala Val Phe Asp 20 25 30 Glu Ala Asp Phe Pro Ala Val Ala Val Tyr Leu Thr Gly Ala Glu Tyr 35 40 45 Thr Gly Glu Glu Leu Asp Ser Asp Thr Trp Gln Ala Glu Leu His Ile 50 55 60 Glu Val Phe Leu Pro Ala Gln Val Pro Asp Ser Glu Leu Asp Ala Trp 65 70 75 80 Met Glu Ser Arg Ile Tyr Pro Val Met Ser Asp Ile Pro Ala Leu Ser 85 90 95 Asp Leu Ile Thr Ser Met Val Ala Ser Gly Tyr Asp Tyr Arg Arg Asp 100 105 110 Asp Asp Ala Gly Leu Trp Ser Ser Ala Asp Leu Thr Tyr Val Ile Thr 115 120 125 Tyr Glu Met * 130 <210> 662 <211> 247 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20695..21435) <400> 662 Met Pro Thr Pro Asn Pro Leu Ala Pro Val Lys Gly Ala Gly Thr Thr 1 5 10 15 Leu Trp Val Tyr Asn Gly Asn Gly Asp Pro Tyr Ala Asn Pro Leu Ser 20 25 30 Asp Asn Asp Trp Ser Arg Leu Ala Lys Val Lys Asp Leu Thr Pro Gly 35 40 45 Glu Leu Thr Ala Glu Ser Tyr Asp Asp Ser Tyr Leu Asp Asp Glu Asp 50 55 60 Ala Asp Trp Ala Ala Thr Gly Gln Gly Gln Lys Ser Ala Gly Asp Thr 65 70 75 80 Ser Phe Thr Leu Ala Trp Met Pro Gly Glu Gln Gly Gln Gln Ala Leu 85 90 95 Leu Ala Trp Phe Asn Glu Gly Asp Thr Arg Ala Tyr Lys Ile Arg Phe 100 105 110 Pro Asn Gly Thr Val Asp Val Phe Arg Gly Trp Val Ser Ser Ile Gly 115 120 125 Lys Ala Val Thr Ala Lys Glu Val Ile Thr Arg Thr Val Lys Val Thr 130 135 140 Asn Val Gly Arg Pro Ser Met Ala Glu Asp Arg Ser Thr Val Thr Ala 145 150 155 160 Ala Thr Gly Met Thr Val Thr Pro Ala Ser Thr Ser Val Val Lys Gly 165 170 175 Gln Ser Thr Thr Leu Thr Val Ala Phe Gln Pro Glu Gly Ala Thr Asp 180 185 190 Lys Ser Phe Arg Ala Val Ser Ala Asp Lys Thr Lys Ala Thr Val Ser 195 200 205 Val Ser Gly Met Thr Ile Thr Val Lys Gly Val Ala Ala Gly Lys Val 210 215 220 Asn Ile Pro Val Val Ser Gly Asn Gly Glu Phe Ala Ala Val Ala Glu 225 230 235 240 Ile Asn Val Thr Ala Ser * 245 <210> 663 <211> 141 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21451..21873) <400> 663 Met Phe Leu Lys Thr Glu Ser Phe Glu His Asn Gly Val Thr Val Thr 1 5 10 15 Leu Ser Glu Leu Ser Ala Leu Gln Arg Ile Glu His Leu Ala Leu Met 20 25 30 Lys Arg Gln Ala Glu Gln Ala Glu Ser Asp Ser Asn Arg Lys Phe Thr 35 40 45 Val Glu Asp Ala Ile Arg Thr Gly Ala Phe Val Val Ala Met Ser Leu 50 55 60 Trp His Asn His Pro Lys Lys Thr Gln Met Pro Ser Met Asn Glu Ala 65 70 75 80 Val Lys Gln Ile Glu Gln Glu Val Leu Thr Thr Trp Pro Ala Glu Ala 85 90 95 Ile Ser His Ala Glu Asn Val Val Tyr Arg Leu Ser Gly Met Tyr Glu 100 105 110 Phe Val Val Asn Asp Ala Pro Glu Gln Ala Glu Asp Ala Gly Pro Ala 115 120 125 Glu Pro Val Ser Ala Gly Lys Cys Ser Thr Val Ser * 130 135 140 <210> 664 <211> 145 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21855..22289) <400> 664 Val Phe Asp Gly Glu Leu Ser Phe Ala Leu Lys Leu Ala Arg Glu Met 1 5 10 15 Gly Arg Pro Asp Trp Arg Ala Met Leu Ala Gly Met Ser Ser Thr Glu 20 25 30 Tyr Ala Asp Trp His Arg Phe Tyr Ser Thr His Tyr Phe His Asp Val 35 40 45 Leu Leu Asp Met His Phe Ser Gly Leu Thr Tyr Thr Val Leu Ser Leu 50 55 60 Phe Phe Ser Asp Pro Asp Met His Pro Leu Asp Phe Ser Leu Leu Asn 65 70 75 80 Arg Arg Glu Ala Asp Glu Glu Pro Glu Asp Asp Val Leu Met Gln Lys 85 90 95 Ala Ala Gly Leu Ala Gly Gly Val Arg Phe Gly Pro Asp Gly Asn Glu 100 105 110 Val Ile Pro Ala Ser Pro Asp Val Ala Asp Met Thr Glu Asp Asp Val 115 120 125 Met Leu Met Thr Val Ser Glu Gly Ile Ala Gly Gly Val Arg Tyr Gly 130 135 140 * <210> 665 <211> 850 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22282..24831) <400> 665 Met Ala Glu Pro Val Gly Asp Leu Val Val Asp Leu Ser Leu Asp Ala 1 5 10 15 Ala Arg Phe Asp Glu Gln Met Ala Arg Val Arg Arg His Phe Ser Gly 20 25 30 Thr Glu Ser Asp Ala Lys Lys Thr Ala Ala Val Val Glu Gln Ser Met 35 40 45 Ser Arg Gln Ala Leu Ala Ala Gln Lys Ala Gly Ile Ser Val Gly Gln 50 55 60 Tyr Lys Ala Ala Met Arg Met Leu Pro Ala Gln Phe Thr Asp Val Ala 65 70 75 80 Thr Gln Leu Ala Gly Gly Gln Ser Pro Trp Leu Ile Leu Leu Gln Gln 85 90 95 Gly Gly Gln Val Lys Asp Ser Phe Gly Gly Met Ile Pro Met Phe Arg 100 105 110 Gly Leu Ala Gly Ala Ile Thr Leu Pro Met Val Gly Ala Thr Ser Leu 115 120 125 Ala Val Ala Thr Gly Ala Leu Ala Tyr Ala Trp Tyr Gln Gly Asn Ser 130 135 140 Thr Leu Ser Asp Phe Asn Lys Thr Leu Val Leu Ser Gly Asn Gln Ala 145 150 155 160 Gly Leu Thr Ala Asp Arg Met Leu Val Leu Ser Arg Ala Gly Gln Ala 165 170 175 Ala Gly Leu Thr Phe Asn Gln Thr Ser Glu Ser Leu Ser Ala Leu Val 180 185 190 Lys Ala Gly Val Ser Gly Glu Ala Gln Ile Ala Ser Ile Ser Gln Ser 195 200 205 Val Ala Arg Phe Ser Ser Ala Ser Gly Val Glu Val Asp Lys Val Ala 210 215 220 Glu Ala Phe Gly Lys Leu Thr Thr Asp Pro Thr Ser Gly Leu Thr Ala 225 230 235 240 Met Ala Arg Gln Phe His Asn Val Thr Ala Glu Gln Ile Ala Tyr Val 245 250 255 Ala Gln Leu Gln Arg Ser Gly Glu Glu Ala Gly Ala Leu Gln Ala Ala 260 265 270 Asn Glu Ala Ala Thr Lys Gly Phe Asp Asp Gln Thr Arg Arg Leu Lys 275 280 285 Glu Asn Met Gly Thr Leu Glu Thr Trp Ala Asp Arg Thr Ala Arg Ala 290 295 300 Phe Lys Ser Met Trp Asp Ala Val Leu Asp Ile Gly Arg Pro Asp Thr 305 310 315 320 Ala Gln Glu Met Leu Ile Lys Ala Glu Ala Ala Phe Lys Lys Ala Asp 325 330 335 Asp Ile Trp Asn Leu Arg Lys Asp Asp Tyr Phe Val Asn Asp Glu Ala 340 345 350 Arg Ala Arg Tyr Trp Asp Asp Arg Glu Lys Ala Arg Leu Ala Leu Glu 355 360 365 Ala Ala Arg Lys Lys Ala Glu Gln Gln Ser Gln Gln Asp Lys Asn Ala 370 375 380 Gln Gln Gln Ser Asp Thr Glu Ala Ser Arg Leu Lys Tyr Thr Glu Glu 385 390 395 400 Ala Gln Lys Ala Tyr Glu Arg Leu Gln Thr Pro Leu Glu Lys Tyr Thr 405 410 415 Ala Arg Gln Glu Glu Leu Asn Lys Ala Leu Lys Asp Gly Lys Ile Leu 420 425 430 Gln Ala Asp Tyr Asn Thr Leu Met Ala Ala Ala Lys Lys Asp Tyr Glu 435 440 445 Ala Thr Leu Lys Lys Pro Lys Gln Ser Gly Val Lys Val Ser Ala Gly 450 455 460 Asp Arg Gln Glu Asp Ser Ala His Ala Ala Leu Leu Thr Leu Gln Ala 465 470 475 480 Glu Leu Arg Met Leu Glu Lys His Ala Gly Ala Asn Glu Lys Ile Ser 485 490 495 Gln Gln Arg Arg Asp Leu Trp Lys Ala Glu Ser Gln Phe Ala Val Leu 500 505 510 Glu Glu Ala Ala Gln Arg Arg Gln Leu Ser Ala Gln Glu Lys Ser Leu 515 520 525 Leu Ala His Lys Asp Glu Thr Leu Glu Tyr Lys Arg Gln Leu Ala Val 530 535 540 Leu Gly Asp Lys Val Thr Tyr Gln Glu His Leu Asn Ala Leu Ala Gln 545 550 555 560 Gln Ala Asp Lys Phe Ala Gln Gln Gln Arg Ala Lys Arg Ala Ala Ile 565 570 575 Asp Ala Lys Asn Arg Gly Leu Thr Asp Arg Gln Ala Ala Arg Glu Ala 580 585 590 Thr Glu Gln Arg Leu Lys Glu Gln Tyr Gly Asp Asn Pro Leu Ala Leu 595 600 605 Asn Asn Val Met Ser Glu Gln Lys Lys Thr Trp Ala Ala Glu Asp Gln 610 615 620 Leu Arg Gly Ser Trp Met Ala Gly Leu Arg Ser Gly Trp Ser Glu Trp 625 630 635 640 Glu Glu Ser Ala Thr Asp Ser Met Ser Gln Val Lys Ser Ala Ala Thr 645 650 655 Gln Thr Phe Asp Gly Ile Ala Gln Asn Met Ala Ala Met Leu Thr Gly 660 665 670 Ser Glu Gln Asn Trp Arg Ser Phe Thr Arg Ser Val Leu Ser Met Met 675 680 685 Thr Glu Ile Leu Leu Lys Gln Ala Met Val Gly Ile Val Gly Ser Ile 690 695 700 Gly Ser Ala Ile Gly Gly Gly Ala Ser Ala Ser Gly Gly Thr Ala Ile 705 710 715 720 Gln Ala Ala Ala Ala Lys Phe His Phe Ala Ala Gly Gly Phe Thr Gly 725 730 735 Thr Gly Gly Lys Tyr Glu Pro Ala Gly Ile Val His Arg Gly Glu Phe 740 745 750 Val Phe Thr Lys Glu Ala Thr Ser Arg Ile Gly Val Gly Asn Leu Tyr 755 760 765 Arg Leu Met Arg Gly Tyr Ala Thr Gly Gly Tyr Val Gly Thr Pro Gly 770 775 780 Ser Met Ala Asp Ser Arg Ser Gln Ala Ser Gly Thr Phe Glu Gln Asn 785 790 795 800 Asn His Val Val Ile Asn Asn Asp Gly Thr Asn Gly Gln Ile Gly Pro 805 810 815 Gln Ala Leu Lys Ala Val Tyr Asp Val Ala Arg Lys Ala Ala Met Asp 820 825 830 Val Val Thr Gly Gln Met Arg Asp Gly Gly Leu Phe Ser Gly Gly Gly 835 840 845 Arg * <210> 666 <211> 110 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24828..25157) <400> 666 Met Lys Thr Phe Arg Trp Lys Val Lys Pro Gly Met Asp Val Ala Ser 1 5 10 15 Ala Pro Ser Val Arg Lys Val Arg Phe Gly Asp Gly Tyr Ser Gln Arg 20 25 30 Ala Pro Ala Gly Leu Asn Ala Asp Leu Lys Thr Tyr Ser Val Thr Leu 35 40 45 Ser Val Pro Arg Trp Glu Ala Thr Ala Leu Glu Ser Phe Leu Ala Glu 50 55 60 His Gly Gly Trp Lys Ala Phe Leu Trp Thr Pro Pro Tyr Glu Trp Arg 65 70 75 80 Gln Ile Lys Val Thr Cys Ala Lys Trp Ser Ser Arg Val Ser Met Leu 85 90 95 Arg Val Glu Phe Ser Ala Glu Phe Glu Gln Val Val Asn * 100 105 <210> 667 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25157..25855) <400> 667 Met Gln Asp Ile Arg Gln Glu Thr Leu Asn Glu Cys Thr Arg Ala Glu 1 5 10 15 Gln Ser Ala Ser Val Val Leu Trp Glu Ile Asp Leu Thr Glu Val Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Gln Asn Glu Lys Gly Glu Pro 35 40 45 Val Thr Trp Gln Gly Arg Gln Tyr Gln Pro Tyr Pro Ile Gln Gly Ser 50 55 60 Gly Phe Glu Leu Asn Gly Lys Gly Thr Ser Thr Arg Pro Thr Leu Thr 65 70 75 80 Val Ser Asn Leu Tyr Gly Met Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Gly Thr Val Val Arg Arg Lys Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Asn Gly Asn Ser Asp Ala Asp Pro Glu 115 120 125 Gln Glu Val Ile Ser Arg Trp Arg Ile Glu Gln Cys Ser Glu Leu Ser 130 135 140 Ala Val Ser Ala Ser Phe Val Leu Ser Thr Pro Thr Glu Thr Asp Gly 145 150 155 160 Ala Val Phe Pro Gly Arg Ile Met Leu Ala Asn Thr Cys Thr Trp Thr 165 170 175 Tyr Arg Gly Asp Glu Cys Gly Tyr His Gly Pro Ala Val Ala Asp Glu 180 185 190 Tyr Asp Gln Pro Thr Ser Asp Ile Thr Lys Asp Lys Cys Ser Lys Cys 195 200 205 Leu Ser Gly Cys Lys Phe Arg Asn Asn Val Gly Asn Phe Gly Gly Phe 210 215 220 Leu Ser Ile Asn Lys Leu Ser Gln * 225 230 <210> 668 <211> 248 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25861..26604) <400> 668 Met Thr Gln Thr Glu Ser Ala Ile Leu Ala His Ala Arg Arg Cys Ala 1 5 10 15 Pro Ala Glu Ser Cys Gly Phe Val Val Ser Thr Pro Glu Gly Glu Arg 20 25 30 Tyr Phe Pro Cys Val Asn Ile Ser Gly Glu Pro Glu Ala Tyr Phe Arg 35 40 45 Met Ser Pro Glu Asp Trp Leu Gln Ala Glu Met Gln Gly Glu Ile Val 50 55 60 Ala Leu Val His Ser His Pro Gly Gly Leu Pro Trp Leu Ser Glu Ala 65 70 75 80 Asp Arg Arg Leu Gln Val Gln Ser Asp Leu Pro Trp Trp Leu Val Cys 85 90 95 Arg Gly Thr Ile His Lys Phe Arg Cys Val Pro His Leu Thr Gly Arg 100 105 110 Arg Phe Glu His Gly Val Thr Asp Cys Tyr Thr Leu Phe Arg Asp Ala 115 120 125 Tyr His Leu Ala Gly Ile Glu Met Pro Asp Phe His Arg Glu Asp Asp 130 135 140 Trp Trp Arg His Gly Gln Asn Leu Tyr Leu Asp Asn Leu Glu Ala Thr 145 150 155 160 Gly Leu Tyr Gln Val Pro Leu Ser Ser Ala Gln Pro Gly Asp Val Leu 165 170 175 Leu Cys Cys Phe Gly Ser Ser Val Pro Asn His Ala Ala Ile Tyr Cys 180 185 190 Gly Asp Gly Glu Leu Leu His His Ile Pro Glu Gln Leu Ser Lys Arg 195 200 205 Glu Arg Tyr Thr Asp Lys Trp Gln Arg Arg Thr His Ser Leu Trp Arg 210 215 220 His Arg Ala Trp Arg Ala Ser Ala Phe Thr Gly Ile Cys Asn Asp Leu 225 230 235 240 Ala Ala Ala Ser Thr Phe Val * 245 <210> 669 <211> 224 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26502..27173) <400> 669 Met Ala Ala Thr His Thr Leu Pro Leu Ala Ser Pro Gly Met Ala Arg 1 5 10 15 Ile Cys Leu Tyr Gly Asp Leu Gln Arg Phe Gly Arg Arg Ile Asp Leu 20 25 30 Arg Val Lys Thr Gly Ala Glu Ala Ile Arg Ala Leu Ala Thr Gln Leu 35 40 45 Pro Val Phe Arg Gln Lys Leu Ser Asp Gly Trp Tyr Gln Val Arg Ile 50 55 60 Thr Gly Arg Asp Val Ser Thr Ser Gly Leu Thr Ala Gln Leu His Glu 65 70 75 80 Thr Leu Pro Asp Gly Ala Val Ile His Ile Val Pro Arg Val Ala Gly 85 90 95 Ala Lys Ser Gly Gly Val Phe Gln Ile Val Leu Gly Ala Ala Ala Ile 100 105 110 Ala Gly Ser Phe Phe Thr Ala Gly Ala Thr Leu Ala Ala Trp Gly Ala 115 120 125 Ala Ile Gly Ala Gly Gly Met Thr Gly Ile Leu Phe Ser Leu Gly Ala 130 135 140 Ser Met Val Leu Gly Gly Val Ala Gln Met Leu Ala Pro Lys Ala Arg 145 150 155 160 Thr Pro Arg Thr Gln Thr Thr Asp Asn Gly Lys Gln Asn Thr Tyr Phe 165 170 175 Ser Ser Leu Asp Asn Met Val Ala Gln Gly Asn Val Leu Pro Val Leu 180 185 190 Tyr Gly Glu Met Arg Val Gly Ser Arg Val Val Ser Gln Glu Ile Ser 195 200 205 Thr Ala Asp Glu Gly Asp Gly Gly Gln Val Val Val Ile Gly Arg * 210 215 220 <210> 670 <211> 1133 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27234..30632) <400> 670 Met Gly Lys Gly Ser Ser Lys Gly His Thr Pro Arg Glu Ala Lys Asp 1 5 10 15 Asn Leu Lys Ser Thr Gln Leu Leu Ser Val Ile Asp Ala Ile Ser Glu 20 25 30 Gly Pro Val Glu Gly Pro Val Asp Gly Leu Lys Ser Val Leu Leu Asn 35 40 45 Ser Thr Pro Val Leu Asp Ser Glu Gly Asn Thr Asn Ile Ser Gly Val 50 55 60 Thr Val Val Phe Arg Ala Gly Glu Gln Glu Gln Thr Pro Pro Glu Gly 65 70 75 80 Phe Glu Ser Ser Gly Ser Glu Thr Val Leu Gly Thr Glu Val Lys Tyr 85 90 95 Asp Thr Pro Ile Thr Arg Thr Ile Thr Ser Ala Asn Ile Asp Arg Leu 100 105 110 Arg Phe Thr Phe Gly Val Gln Ala Leu Val Glu Thr Thr Ser Lys Gly 115 120 125 Asp Arg Asn Pro Ser Glu Val Arg Leu Leu Val Gln Ile Gln Arg Asn 130 135 140 Gly Gly Trp Val Thr Glu Lys Asp Ile Thr Ile Lys Gly Lys Thr Thr 145 150 155 160 Ser Gln Tyr Leu Ala Ser Val Val Val Asp Asn Leu Pro Pro Arg Pro 165 170 175 Phe Asn Ile Arg Met Arg Arg Met Thr Pro Asp Ser Thr Thr Asp Gln 180 185 190 Leu Gln Asn Lys Thr Leu Trp Ser Ser Tyr Thr Glu Ile Ile Asp Val 195 200 205 Lys Gln Cys Tyr Pro Asn Thr Ala Leu Val Gly Val Gln Val Asp Ser 210 215 220 Glu Gln Phe Gly Ser Gln Lys Val Ser Arg Asn Tyr His Leu Arg Gly 225 230 235 240 Arg Ile Leu Gln Val Pro Ser Asn Tyr Asn Pro Gln Thr Arg Gln Tyr 245 250 255 Ser Gly Ile Trp Asp Gly Thr Phe Lys Pro Ala Tyr Ser Asn Asn Met 260 265 270 Ala Trp Cys Leu Trp Asp Met Leu Thr His Pro Arg Tyr Gly Met Gly 275 280 285 Lys Arg Leu Gly Ala Ala Asp Val Asp Lys Trp Ala Leu Tyr Val Ile 290 295 300 Gly Gln Tyr Cys Asp Gln Ser Val Pro Asp Gly Phe Gly Gly Thr Glu 305 310 315 320 Pro Arg Ile Thr Cys Asn Ala Tyr Leu Thr Thr Gln Arg Lys Ala Trp 325 330 335 Asp Val Leu Ser Asp Phe Cys Ser Ala Met Arg Cys Met Pro Val Trp 340 345 350 Asn Gly Gln Thr Leu Thr Phe Val Gln Asp Arg Pro Ser Asp Lys Val 355 360 365 Trp Thr Tyr Asn Arg Ser Asn Val Val Met Pro Asp Asp Gly Ala Ser 370 375 380 Phe Arg Tyr Ser Phe Ser Ala Leu Lys Asp Arg His Asn Ala Val Glu 385 390 395 400 Val Asn Trp Ile Asp Pro Asp Asn Gly Trp Glu Thr Ala Thr Glu Leu 405 410 415 Val Glu Asp Thr Gln Ala Ile Leu Arg Tyr Gly Arg Asn Val Thr Lys 420 425 430 Met Asp Ala Phe Gly Cys Thr Ser Arg Gly Gln Ala His Arg Ala Gly 435 440 445 Leu Trp Leu Ile Lys Thr Glu Leu Leu Glu Thr Gln Thr Val Asp Phe 450 455 460 Ser Val Gly Ala Glu Gly Leu Arg His Val Pro Gly Asp Val Ile Glu 465 470 475 480 Ile Cys Asp Asp Asp Tyr Ala Gly Ile Ser Ile Gly Gly Arg Val Leu 485 490 495 Ala Val Asn Ser Gln Thr Arg Thr Leu Thr Leu Asp Arg Glu Ile Thr 500 505 510 Leu Pro Ser Ser Gly Thr Thr Leu Ile Ser Leu Val Asp Gly Ser Gly 515 520 525 Asn Pro Val Ser Val Glu Val Gln Ser Val Thr Asp Gly Val Lys Val 530 535 540 Lys Val Ser Arg Val Pro Asp Gly Val Ala Gly Tyr Ser Val Trp Gly 545 550 555 560 Leu Lys Leu Pro Thr Leu Arg Gln Arg Leu Phe Arg Cys Val Ser Ile 565 570 575 Arg Glu Asn Asp Asp Gly Thr Tyr Ala Ile Thr Ala Val Gln His Val 580 585 590 Pro Glu Lys Glu Ala Ile Val Asp Asn Gly Ala His Phe Asp Gly Asp 595 600 605 Leu Ser Gly Thr Val Asn Gly Val Thr Pro Pro Ala Val Gln His Leu 610 615 620 Thr Ala Glu Val Thr Ala Asp Ser Gly Glu Tyr Gln Val Leu Ala Arg 625 630 635 640 Trp Asp Thr Pro Lys Val Val Lys Gly Val Ser Phe Leu Leu Arg Leu 645 650 655 Thr Val Ala Ala Asp Asp Gly Ser Glu Arg Leu Val Ser Thr Ala Arg 660 665 670 Thr Thr Glu Thr Thr Tyr Arg Phe Thr Gln Leu Ala Leu Gly Asn Tyr 675 680 685 Arg Leu Thr Val Arg Ala Val Asn Ala Trp Gly Gln Gln Gly Asp Pro 690 695 700 Ala Ser Val Ser Phe Arg Ile Ala Ala Pro Ala Ala Pro Ser Arg Ile 705 710 715 720 Glu Leu Thr Pro Gly Tyr Phe Gln Ile Thr Ala Thr Pro His Leu Ala 725 730 735 Val Tyr Asp Pro Thr Val Gln Phe Glu Phe Trp Phe Ser Glu Thr Arg 740 745 750 Ile Ala Asp Ile Arg Gln Val Glu Thr Ser Ala Arg Tyr Leu Gly Thr 755 760 765 Ala Leu Tyr Trp Ile Ala Ala Ser Ile Asn Ile Lys Pro Gly His Asp 770 775 780 Tyr Tyr Phe Tyr Ile Arg Ser Val Asn Thr Val Gly Lys Ser Ala Phe 785 790 795 800 Val Glu Ala Val Gly Arg Ala Ser Asp Asp Ala Glu Gly Tyr Leu Asp 805 810 815 Phe Phe Lys Gly Lys Ile Thr Glu Ser His Leu Gly Lys Glu Leu Leu 820 825 830 Glu Lys Val Asp Leu Thr Glu Asp Asn Ala Ser Arg Leu Asp Glu Phe 835 840 845 Ser Lys Glu Trp Lys Asp Ala Asn Asp Lys Trp Asn Ala Met Trp Gly 850 855 860 Val Lys Ile Glu Gln Thr Lys Asp Gly Lys His Tyr Val Ala Gly Ile 865 870 875 880 Gly Leu Ser Met Glu Asp Thr Glu Glu Gly Lys Leu Ser Gln Phe Leu 885 890 895 Val Ala Ala Asn Arg Ile Ala Phe Ile Asp Pro Ala Asn Gly Asn Glu 900 905 910 Thr Pro Met Phe Val Ala Gln Gly Asn Gln Ile Phe Met Asn Asp Val 915 920 925 Phe Leu Lys Arg Leu Thr Ala Pro Thr Ile Thr Ser Gly Gly Asn Pro 930 935 940 Pro Ala Phe Ser Leu Thr Pro Asp Gly Lys Leu Thr Ala Lys Asn Ala 945 950 955 960 Asp Ile Ser Gly Ser Val Asn Ala Asn Ser Gly Thr Leu Asn Asn Val 965 970 975 Thr Ile Asn Glu Asn Cys Gln Ile Lys Gly Lys Leu Ser Ala Asn Gln 980 985 990 Ile Glu Gly Asp Ile Val Lys Thr Val Ser Lys Ser Phe Pro Arg Thr 995 1000 1005 Ser Thr Tyr Ala Ser Gly Thr Ile Thr Val Arg Ile Ser Asp Asp Gln 1010 1015 1020 Lys Phe Asp Arg Gln Val Met Ile Pro Pro Val Leu Phe Arg Gly Gly 1025 1030 1035 1040 Lys His Glu Asn Phe Asn Ser Asn Asn Gln Gln Ser Tyr Trp Tyr Ser 1045 1050 1055 Thr Cys Arg Leu Arg Val Thr Arg Asn Gly Gln Glu Ile Phe Asn Gln 1060 1065 1070 Ser Thr Thr Asp Ala Gln Gly Val Phe Ser Ser Val Ile Asp Met Pro 1075 1080 1085 Ala Gly Gln Gly Thr Leu Thr Leu Thr Phe Thr Val Ser Ser Ser Gly 1090 1095 1100 Ala Asn Asn Trp Thr Pro Thr Thr Ser Ile Ser Asp Leu Leu Val Val 1105 1110 1115 1120 Val Met Lys Lys Ser Thr Ala Gly Ile Ser Ile Ser * 1125 1130 <210> 671 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30699..31298) <400> 671 Met Arg Lys Leu Tyr Ala Ala Ile Leu Ser Ala Ala Ile Cys Leu Ala 1 5 10 15 Val Ser Gly Ala Pro Ala Trp Ala Ser Glu His Gln Ser Thr Leu Ser 20 25 30 Ala Gly Tyr Leu His Ala Arg Thr Asn Val Pro Gly Ser Asp Asp Leu 35 40 45 Asn Gly Ile Asn Val Lys Tyr Arg Tyr Glu Phe Thr Asp Thr Leu Gly 50 55 60 Leu Val Thr Ser Phe Ser Tyr Ala Gly Asp Lys Asn Arg Gln Leu Thr 65 70 75 80 Arg Tyr Ser Asp Thr Arg Trp His Glu Asp Ser Val Arg Asn Arg Trp 85 90 95 Phe Ser Val Met Ala Gly Pro Ser Val Arg Val Asn Glu Trp Phe Ser 100 105 110 Ala Tyr Ala Met Ala Gly Val Ala Tyr Ser Arg Val Ser Thr Phe Ser 115 120 125 Gly Asp Tyr Leu Arg Val Thr Asp Asn Lys Gly Lys Thr His Asp Val 130 135 140 Leu Thr Gly Ser Asp Asp Gly Arg His Ser Asn Thr Ser Leu Ala Trp 145 150 155 160 Gly Ala Gly Val Gln Phe Asn Pro Thr Glu Ser Val Ala Ile Asp Ile 165 170 175 Ala Tyr Glu Gly Ser Gly Ser Gly Asp Trp Arg Thr Asp Gly Phe Ile 180 185 190 Val Gly Val Gly Tyr Lys Phe * 195 <210> 672 <211> 972 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31363..34278) <400> 672 Met Ala Val Lys Ile Ser Gly Val Leu Lys Asp Gly Thr Gly Lys Pro 1 5 10 15 Val Glu Asn Cys Thr Ile Gln Leu Lys Ala Arg Arg Asn Ser Ala Thr 20 25 30 Val Val Val Asn Thr Val Ala Ser Glu Asn Pro Asp Glu Ala Gly Arg 35 40 45 Tyr Ser Met Asp Val Glu Tyr Gly Gln Tyr Ser Val Ile Leu Leu Val 50 55 60 Glu Gly Phe Pro Pro Ser His Ala Gly Thr Ile Thr Val Tyr Glu Asp 65 70 75 80 Ser Gln Pro Gly Thr Leu Asn Asp Phe Leu Gly Ala Met Thr Glu Asp 85 90 95 Asp Val Arg Pro Glu Ala Leu Arg Arg Phe Glu Leu Met Val Glu Glu 100 105 110 Val Ala Arg Asn Ala Ser Ala Val Ala Gln Asn Thr Ala Ala Ala Lys 115 120 125 Lys Ser Ala Ser Asp Ala Ser Thr Ser Ala Arg Glu Ala Ala Thr His 130 135 140 Ala Thr Asp Ala Ala Asp Ser Ala Arg Ala Ala Ser Thr Ser Ala Gly 145 150 155 160 Gln Ala Ala Ser Ser Ala Gln Ser Ala Ser Ser Ser Ala Gly Thr Ala 165 170 175 Ser Thr Lys Ala Thr Glu Ala Ser Lys Ser Ala Ala Ala Ala Glu Ser 180 185 190 Ser Lys Ser Ala Ala Ala Thr Ser Ala Gly Ala Ala Lys Thr Ser Glu 195 200 205 Thr Asn Ala Ala Val Ser Gln Gln Ser Ala Ala Thr Ser Ala Ser Thr 210 215 220 Ala Thr Thr Lys Ala Ser Glu Ala Ala Ser Ser Ala Arg Asp Ala Ser 225 230 235 240 Ala Ser Lys Glu Ala Ala Lys Ser Ser Glu Thr Ser Ala Ala Ser Ser 245 250 255 Ala Ser Ser Ala Ala Ser Ser Ala Thr Ala Ala Gly Asn Ser Ala Lys 260 265 270 Ala Ala Lys Thr Ser Glu Thr Asn Ala Lys Ser Ser Glu Thr Ala Ala 275 280 285 Glu Gln Ser Ala Ser Ala Ala Ala Gly Ser Lys Thr Ala Ala Ala Leu 290 295 300 Ser Ala Ser Ala Ala Ser Thr Ser Ala Gly Gln Ala Ser Ala Ser Ala 305 310 315 320 Thr Ala Ala Gly Lys Ser Ala Glu Ser Ala Ala Ser Ser Ala Ser Thr 325 330 335 Ala Thr Thr Lys Ala Gly Glu Ala Thr Glu Gln Ala Ser Ala Ala Ala 340 345 350 Ser Ser Ala Ser Ala Ala Lys Thr Ser Glu Thr Asn Ala Lys Ala Ser 355 360 365 Glu Thr Ser Ala Glu Ser Ser Lys Thr Ala Ala Ala Ser Ser Ala Ser 370 375 380 Ser Ala Ala Ser Ser Ala Ser Ser Ala Ser Ala Ser Lys Asp Glu Ala 385 390 395 400 Thr Arg Gln Ala Ser Ala Ala Lys Ser Ser Ala Thr Thr Ala Ser Thr 405 410 415 Lys Ala Thr Glu Ala Ala Gly Ser Ala Thr Ala Ala Ala Gln Ser Lys 420 425 430 Ser Thr Ala Glu Ser Ala Ala Thr Arg Ala Glu Thr Ala Ala Lys Arg 435 440 445 Ala Glu Asp Ile Ala Ser Ala Val Ala Leu Glu Asp Ala Ser Thr Thr 450 455 460 Lys Lys Gly Ile Val Gln Leu Ser Ser Ala Thr Asn Ser Thr Ser Glu 465 470 475 480 Ser Leu Ala Ala Thr Pro Lys Ala Val Lys Ala Ala Tyr Glu Leu Ala 485 490 495 Asn Gly Lys Tyr Thr Ala Gln Asp Ala Thr Thr Ala Gln Lys Gly Ile 500 505 510 Val Gln Leu Ser Asn Ala Thr Asn Ser Thr Ser Glu Met Leu Ala Ala 515 520 525 Thr Pro Lys Ser Val Lys Ala Ala Tyr Asp Leu Ala Asn Gly Lys Tyr 530 535 540 Thr Ala Gln Asp Ala Thr Thr Ala Gln Lys Gly Ile Val Gln Leu Ser 545 550 555 560 Ser Ala Thr Asn Ser Ala Ser Glu Thr Leu Ala Ala Thr Pro Lys Ala 565 570 575 Val Lys Ala Ala Asn Asp Asn Ala Asn Gly Arg Val Pro Ser Ala Arg 580 585 590 Lys Val Asn Gly Lys Ala Leu Ser Ser Asp Ile Thr Leu Thr Pro Lys 595 600 605 Asp Ile Gly Thr Leu Asn Ser Thr Thr Met Ser Phe Ser Gly Gly Ala 610 615 620 Gly Trp Phe Lys Leu Ala Thr Val Thr Met Pro Gln Ala Ser Ser Val 625 630 635 640 Val Ser Ile Thr Leu Ile Gly Gly Ala Gly Phe Asn Val Gly Ser Pro 645 650 655 Gln Gln Ala Gly Ile Ser Glu Leu Val Leu Arg Ala Gly Asn Gly Asn 660 665 670 Pro Lys Gly Ile Thr Gly Ala Leu Trp Gln Arg Thr Ser Thr Gly Phe 675 680 685 Thr Asn Phe Ala Trp Val Asn Thr Ser Gly Asp Thr Tyr Asp Ile Tyr 690 695 700 Val Ala Ile Gly Asn Tyr Ala Thr Gly Val Asn Ile Gln Trp Asp Tyr 705 710 715 720 Thr Ser Asn Ala Ser Val Thr Ile His Thr Ser Pro Ala Tyr Ser Ala 725 730 735 Asn Lys Pro Glu Gly Leu Thr Asp Gly Thr Val Tyr Ser Leu Tyr Thr 740 745 750 Pro Ser Glu Gln Phe Tyr Pro Pro Gly Ala Pro Ile Pro Trp Pro Ser 755 760 765 Asp Thr Val Pro Ser Gly Tyr Ala Leu Met Gln Gly Gln Thr Phe Asp 770 775 780 Lys Ser Ala Tyr Pro Lys Leu Ala Ala Ala Tyr Pro Ser Gly Val Ile 785 790 795 800 Pro Asp Met Arg Gly Trp Thr Ile Lys Gly Lys Pro Ala Ser Gly Arg 805 810 815 Ala Val Leu Ser Gln Glu Gln Asp Gly Ile Lys Ser His Thr His Ser 820 825 830 Ala Ser Ala Ser Ser Thr Asp Leu Gly Thr Lys Thr Thr Ser Ser Phe 835 840 845 Asp Tyr Gly Thr Lys Ser Thr Asn Asn Thr Gly Ala His Thr His Ser 850 855 860 Val Ser Gly Thr Ala Ala Ser Ala Gly Asn His Thr His Ser Val Thr 865 870 875 880 Gly Ala Ser Ala Val Ser Gln Trp Ser Gln Asn Gly Ser Val His Lys 885 890 895 Val Val Ser Ala Ala Ser Val Asn Thr Ser Ala Ala Gly Ala His Thr 900 905 910 His Ser Val Ser Gly Thr Ala Ala Ser Ala Gly Ala His Ala His Thr 915 920 925 Val Gly Ile Gly Ala His Thr His Ser Val Ala Ile Gly Ser His Gly 930 935 940 His Thr Ile Thr Val Asn Ala Ala Gly Asn Ala Glu Asn Thr Val Lys 945 950 955 960 Asn Ile Ala Phe Asn Tyr Ile Val Arg Leu Ala * 965 970 <210> 673 <211> 194 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34278..34859) <400> 673 Met Ala Phe Arg Met Ser Glu Gln Pro Arg Thr Ile Lys Ile Tyr Asn 1 5 10 15 Leu Leu Thr Gly Thr Asn Glu Phe Ile Gly Glu Gly Asp Ala Tyr Ile 20 25 30 Pro Pro His Thr Gly Leu Pro Ala Asn Ser Thr Tyr Ile Ala Pro Pro 35 40 45 Asp Ile Pro Ala Gly Phe Val Ala Val Phe Asn Ser Asp Glu Ser Ser 50 55 60 Trp His Leu Val Glu Asp His Arg Gly Lys Thr Val Tyr Asp Val Ala 65 70 75 80 Ser Gly Asp Ala Leu Phe Ile Ser Glu Leu Gly Ser Leu Pro Glu Asn 85 90 95 Val Thr Trp Leu Ser Pro Glu Gly Glu Phe Gln Lys Trp Asn Gly Thr 100 105 110 Ala Trp Val Lys Asp Ala Glu Ala Glu Lys Leu Phe Arg Ile Arg Glu 115 120 125 Ala Glu Glu Thr Lys Asn Ser Leu Met Gln Val Ala Ser Glu His Ile 130 135 140 Ala Pro Leu Gln Asp Ala Val Asp Leu Glu Ile Ala Thr Glu Glu Glu 145 150 155 160 Ala Ser Leu Leu Glu Ala Trp Lys Lys Tyr Arg Val Leu Leu Asn Arg 165 170 175 Val Asp Thr Ser Thr Ala Pro Asp Ile Glu Trp Pro Val Ile Pro Glu 180 185 190 Val * <210> 674 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34979..35869) <400> 674 Met Phe Arg His Val Lys Lys Leu Gln Tyr Thr Val Arg Val Ser Glu 1 5 10 15 Pro Asn Pro Gly Leu Ala Asn Leu Leu Leu Glu Gln Phe Gly Gly Pro 20 25 30 Gln Gly Glu Leu Ala Ala Ala Cys Arg Tyr Phe Thr Gln Gly Leu Ser 35 40 45 Asp Glu Asp Ala Gly Arg Arg Asp Met Leu Met Asp Ile Ala Thr Glu 50 55 60 Glu Leu Ser His Leu Glu Ile Ile Gly Ser Leu Val Gly Met Leu Asn 65 70 75 80 Lys Gly Ala Lys Gly Ala Leu Ala Glu Gly Thr Glu Asn Glu Ala Glu 85 90 95 Leu Tyr Arg Ser Leu Thr Gln Asn Gly Asn Asp Ser His Ile Thr Ser 100 105 110 Leu Leu Tyr Gly Gly Gly Pro Ala Leu Thr Asn Ser Ala Gly Val Pro 115 120 125 Trp Thr Ala Ala Tyr Val Asp Thr Ile Gly Glu Val Thr Ala Asp Leu 130 135 140 Arg Ser Asn Ile Ala Ala Glu Ala Arg Ala Lys Ile Ile Tyr Glu Arg 145 150 155 160 Leu Ile Asn Val Thr Asp Asp Pro Gly Val Lys Asp Thr Leu Ala Phe 165 170 175 Leu Met Thr Arg Glu Ala Ala His Met Leu Ser Phe Glu Lys Ala Leu 180 185 190 His Ser Ile Arg Asn Thr Phe Pro Pro Gly Lys Leu Pro Pro Leu Glu 195 200 205 Lys Tyr Lys Asn Val Tyr Tyr Asn Met Ser Glu Gly Glu Asp Val Arg 210 215 220 Gly Ser Trp Asn Ser Asp Glu Asn Phe Asp Tyr Val Ser Asp Pro Val 225 230 235 240 Ser Ala Val Asp Gly Gly Asp Gly Lys Ala Ser Ile Asn Leu Ser Thr 245 250 255 Lys Gln Glu Ala Met Ile Lys Ala Met Ala Thr Arg Leu Lys Ser His 260 265 270 Glu Asp Ile Asn Pro Val Thr Gly Ala Glu Leu Ala Glu Gly Glu Pro 275 280 285 Gln Thr Lys Ile Asn Ser Lys Asn * 290 295 <210> 675 <211> 169 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35888..36394) <400> 675 Met Asn Arg Ile Glu His Tyr His Asp Trp Leu Arg Asp Ala His Ala 1 5 10 15 Met Glu Lys Gln Ala Glu Lys Met Leu Glu Ser Met Ala Ser Arg Ile 20 25 30 Glu Asn Tyr Pro Glu Leu Arg Ser Arg Ile Glu Gln His Ile Ser Glu 35 40 45 Thr Lys Asn Gln Leu Ser Gln Leu Glu Ser Ile Leu Asp Arg Asn Asn 50 55 60 Ile Ser Arg Ser Val Ile Lys Asp Ser Met Ser Lys Met Ala Ala Phe 65 70 75 80 Gly Gln Ser Ile Gly Gly Ile Phe Pro Ser Asp Glu Ile Val Lys Gly 85 90 95 Ser Ile Ser Gly Tyr Val Phe Glu Gln Phe Glu Ile Ala Cys Tyr Thr 100 105 110 Ser Leu Leu Ala Ala Ala Lys Asn Ala Gly Asp Thr Ala Ser Val Pro 115 120 125 Ile Ile Glu Ala Ile Leu Asn Glu Glu Lys Gln Met Ala Glu Trp Leu 130 135 140 Leu Asn His Ile Pro Asp Thr Thr Glu Gln Phe Met Val Arg Ser Glu 145 150 155 160 Ile Asp Gly Val Glu Ala Lys Lys * 165 <210> 676 <211> 167 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36431..36931) <400> 676 Met Gln Ile Lys Ser Val Glu Asp Ile Phe Ile His Leu Leu Ser Asp 1 5 10 15 Thr Tyr Ser Ala Glu Lys Gln Leu Thr Lys Ala Leu Ser Lys Leu Ser 20 25 30 Arg Ser Ala Tyr Ser Asp Lys Leu Thr Ala Ala Phe Gln Ser His Leu 35 40 45 Asp Glu Thr His Gly Gln Ile Glu Arg Ile Asp Gln Val Val Asp Ser 50 55 60 Glu Asp Gly Leu Lys Leu Lys Arg Ile Lys Cys Ala Ala Met Glu Gly 65 70 75 80 Leu Ile Glu Glu Ala Asn Glu Val Ile Glu Ser Thr Asp Lys Asn Glu 85 90 95 Val Arg Asp Ala Ala Leu Ile Ala Ala Ala Gln Lys Val Glu His Tyr 100 105 110 Glu Ile Ala Ser Tyr Gly Thr Leu Val Thr Leu Ala Glu Gln Leu Gly 115 120 125 Tyr Lys Lys Ala Ala Lys Leu Leu Lys Glu Thr Leu Glu Glu Glu Lys 130 135 140 Ala Thr Asp Val Lys Leu Thr Asp Leu Ala Phe Asn Asn Val Asn Lys 145 150 155 160 Lys Ala Gln Asp Asn Ser * 165 <210> 677 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37010..37192) <400> 677 Met Thr Glu His Arg Gly Gly Ala Gly Asn Phe Ala Glu Asp Arg Gln 1 5 10 15 Lys Ala Ser Asp Ala Gly Arg Lys Gly Gly Gln His Ser Gly Gly Asn 20 25 30 Phe Lys Asn Asp Pro Gln Arg Ala Ser Glu Ala Gly Lys Lys Gly Gly 35 40 45 Gln Asn Ser His Gly Gly Gly Arg Lys Ser Asp Ser * 50 55 60 <210> 678 <211> 144 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37690..38121) <400> 678 Met Asp Leu Asn Glu Ala Ser Leu Asn Ala Ala Ser Thr Arg Ala Gly 1 5 10 15 Glu Ser Lys Ile Lys His Lys Ile Ser His Asp Val Phe Glu Pro Tyr 20 25 30 Pro Ala Ala Leu His Gly Gln Phe Asp Ser Ile Ser Met Phe Tyr Leu 35 40 45 Leu His Cys Leu Pro Gly Asn Ile Ser Thr Lys Ser Cys Val Ile Arg 50 55 60 Asn Ala Ala Gln Ala Leu Thr Asp Asp Gly Thr Leu Tyr Gly Ala Thr 65 70 75 80 Ile Leu Gly Asp Gly Val Val His Asn Ser Phe Gly Gln Lys Leu Met 85 90 95 Arg Ile Tyr Asn Gln Lys Gly Ile Phe Ser Asn Thr Lys Asp Ser Glu 100 105 110 Glu Gly Leu Thr His Ile Leu Ser Glu His Phe Glu Asn Val Lys Thr 115 120 125 Lys Val Gln Gly Thr Val Val Met Phe Ser Ala Ser Gly Lys Lys * 130 135 140 <210> 679 <211> 83 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38415..38663) <400> 679 Met Leu Pro Gln His Ser Asp Ile Glu Ile Ala Trp Tyr Ala Ala Ile 1 5 10 15 Gln Gln Glu Pro Asn Gly Trp Lys Thr Val Thr Thr Gln Phe Tyr Ile 20 25 30 Gln Glu Phe Ser Glu Tyr Ile Ala Pro Leu Gln Asp Ala Val Asp Leu 35 40 45 Glu Ile Ala Thr Glu Glu Glu Arg Ser Leu Leu Glu Ala Trp Asn Lys 50 55 60 Tyr Arg Val Leu Leu Asn Arg Val Asp Thr Ser Val Ala Arg Lys Arg 65 70 75 80 Thr Ala * <210> 680 <211> 127 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38739..39119) <400> 680 Met Gln Lys Asn Val Thr Pro Gly Arg Arg Lys Gly Cys Pro Asn Tyr 1 5 10 15 Pro Pro Glu Phe Lys Gln Gln Leu Val Ala Ala Ser Cys Glu Pro Gly 20 25 30 Ile Ser Ile Ser Lys Leu Ala Leu Glu Asn Gly Ile Asn Ala Asn Leu 35 40 45 Leu Phe Lys Trp Arg Gln Gln Trp Arg Glu Gly Lys Leu Leu Leu Pro 50 55 60 Ser Ser Glu Ser Pro Gln Leu Leu Pro Val Thr Leu Asp Ala Ala Ala 65 70 75 80 Glu Gln Pro Glu Ser Leu Ala Glu Asp Pro Glu Thr Leu Ser Ile Ser 85 90 95 Cys Glu Val Thr Phe Arg His Gly Thr Leu Arg Phe Asn Gly Asn Val 100 105 110 Ser Glu Lys Leu Leu Thr Leu Leu Ile Gln Glu Leu Lys Arg * 115 120 125 <210> 681 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39116..39463) <400> 681 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Asp Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 682 <211> 513 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39513..41051) <400> 682 Met Asn Asp Ile Ser Ser Asp Asp Ile Phe Leu Leu Lys Gln Arg Leu 1 5 10 15 Ala Glu Gln Glu Ala Leu Ile His Ala Leu Gln Glu Lys Leu Ser Asn 20 25 30 Arg Glu Arg Glu Ile Asp His Leu Gln Ala Gln Leu Asp Lys Leu Arg 35 40 45 Arg Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala 50 55 60 Gln Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu 65 70 75 80 Thr Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr 85 90 95 Arg Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg 100 105 110 Leu Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser 115 120 125 Tyr Leu Gly Glu Asp Thr Ala Glu Gln Leu Glu Leu Met Arg Ser Ala 130 135 140 Phe Arg Val Ile Arg Thr Val Arg Glu Lys His Ala Cys Thr Gln Cys 145 150 155 160 Asp Ala Ile Val Gln Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly 165 170 175 Ile Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Ser Lys Tyr Ala 180 185 190 Glu His Thr Pro Leu Tyr Arg Gln Ser Glu Ile Tyr Gly Arg Gln Gly 195 200 205 Val Glu Leu Arg Arg Ser Leu Leu Ser Gly Trp Val Asp Ala Cys Cys 210 215 220 Arg Leu Leu Ser Pro Leu Glu Glu Ala Leu His Gly Tyr Val Met Thr 225 230 235 240 Asp Gly Lys Leu His Ala Asp Asp Thr Pro Val Gln Val Leu Leu Pro 245 250 255 Gly Asn Lys Lys Thr Lys Thr Gly Arg Leu Trp Ala Tyr Val Arg Asp 260 265 270 Asp Arg Asn Ala Gly Ser Ala Leu Ala Pro Ala Val Trp Phe Ala Tyr 275 280 285 Ser Pro Asp Arg Lys Gly Ile His Pro Gln Thr His Leu Ala Cys Phe 290 295 300 Ser Gly Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr 305 310 315 320 Arg Asn Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg 325 330 335 Lys Ile His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu 340 345 350 Ala Leu Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg 355 360 365 Gly Met Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys 370 375 380 Pro Leu Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr 385 390 395 400 Leu Ser Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn 405 410 415 Gln Trp Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile 420 425 430 Asp Asn Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg 435 440 445 Lys Asn Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala 450 455 460 Leu Leu Tyr Ser Leu Ile Gly Thr Cys Lys Leu Asn Asp Val Asp Pro 465 470 475 480 Glu Ser Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val 485 490 495 Asn Arg Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu 500 505 510 * <210> 683 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40958..41122) <400> 683 Met Ser Tyr Lys Gln Leu His Thr Gln Ser Tyr Cys Lys Arg Thr Ala 1 5 10 15 Arg Ala Val Leu Thr Gly Met Cys Tyr Ser Ala Gly Ser Ala Met Arg 20 25 30 His Gly Ser Ser Ser Leu Thr Arg Leu Thr Gly Gln Ser Ala Met Thr 35 40 45 Pro Ser Thr Trp Arg Arg * 50 <210> 684 <211> 495 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41354..42838) <400> 684 Met Arg Lys Ile Ile Thr His Phe Lys Val Val Leu Thr Leu Leu Leu 1 5 10 15 Pro Val Thr Val Ser Ala Gln Gln Ile Gln Trp Gln Ser Cys Met Ala 20 25 30 Ser Gln Phe Asn His Trp Phe Gly Glu Glu Lys Pro Ser Pro Asp Leu 35 40 45 Leu Cys Gly Tyr Leu Ser Val Pro Leu Lys Tyr Thr Asp Thr Gly Gly 50 55 60 Asp Ala Ser Tyr Glu Lys Lys Ser Gln Val Lys Leu Ala Leu Thr Lys 65 70 75 80 Leu Pro Ala Lys Ser Lys His Lys Gly Ser Ile Leu Ile Ile Ser Gly 85 90 95 Gly Pro Gly Leu Pro Gly Ile Asn Pro Tyr Ile Asn Phe Asp Trp Pro 100 105 110 Val Thr Asn Leu Arg Glu Ser Trp Asp Ile Ile Gly Phe Asp Pro Arg 115 120 125 Gly Val Gly Gln Ser Thr Pro Thr Ile Asn Cys Arg Gln Ser Asp Thr 130 135 140 Glu Thr Gln Glu Asn Ile Thr Glu Lys Gln Gln Val Leu Asn Lys Ile 145 150 155 160 Asn Ala Cys Ile His Asn Thr Gly Ala Glu Val Ile Arg His Ile Gly 165 170 175 Ser Asn Glu Ala Val Tyr Asp Ile Asp Arg Ile Arg Gln Ala Leu Gly 180 185 190 Asp Lys Gln Leu Thr Ala Val Ala Tyr Ser Tyr Gly Thr Gln Ile Ala 195 200 205 Ala Leu Tyr Ala Glu Arg Phe Pro Tyr Asn Val Arg Ser Ile Val Leu 210 215 220 Asp Gly Val Val Asp Ile Asp Asp Leu Glu Asp Asn Phe Thr Trp Gln 225 230 235 240 Leu Lys Gln Ala Gln Ser Tyr Gln Glu Thr Phe Asp Arg Phe Ala Ser 245 250 255 Trp Cys Ala Arg Thr Lys Ser Cys Pro Leu Ser Ser Asp Arg Asp Lys 260 265 270 Ala Ile Thr Gln Phe His Glu Leu Leu Ser Lys Leu His His Lys Pro 275 280 285 Leu Leu Asp Ser Lys Gly Glu Asn Ile Ser Ser Asp Glu Leu Ile Ser 290 295 300 Leu Thr Thr Asp Leu Leu Leu Trp Arg Ser Ser Trp Pro Thr Leu Ala 305 310 315 320 Thr Ala Ile Arg Gln Phe Ser Gln Gly Ile Val Ser Asn Glu Ile Glu 325 330 335 Thr Ala Leu Ser Ala Pro Ile Ala Ser Glu Glu Ser Ser Asp Ala Ser 340 345 350 Gly Val Ile Leu Cys Val Asp Gln Gly Asp Glu Gln Leu Thr Pro Glu 355 360 365 Glu Arg Lys Phe Arg Lys Glu Ala Leu Ala Asn Ala Phe Pro Ala Ile 370 375 380 Asn Phe Asp Asn Gly Arg Ser Asp Ser Pro Asp Phe Cys Glu Leu Trp 385 390 395 400 Pro Ile His Ser Asp Leu Asn Lys Thr Arg Leu Lys Asn Thr Val Leu 405 410 415 Pro Ser Gly Leu Leu Phe Val Ala His Lys Tyr Asp Pro Thr Thr Pro 420 425 430 Trp Ile Asn Ala Arg Lys Met Ala Glu Lys Phe Ser Ser Pro Leu Leu 435 440 445 Thr Ile Asn Gly Asp Gly His Thr Leu Ala Leu Thr Gly Val Asn Leu 450 455 460 Cys Val Asp Lys Ala Val Val His His Leu Ile Thr Pro Gln Lys Ile 465 470 475 480 Glu Asn Ile Tyr Cys Pro Gly Asn Ser Glu Ala Glu Ile Gln * 485 490 <210> 685 <211> 318 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43025..43978) <400> 685 Met Arg Ala Lys Leu Leu Gly Ile Val Leu Thr Thr Pro Ile Ala Ile 1 5 10 15 Ser Ser Phe Ala Ser Thr Glu Thr Leu Ser Phe Thr Pro Asp Asn Ile 20 25 30 Asn Ala Asp Ile Ser Leu Gly Thr Leu Ser Gly Lys Thr Lys Glu Arg 35 40 45 Val Tyr Leu Ala Glu Glu Gly Gly Arg Lys Val Ser Gln Leu Asp Trp 50 55 60 Lys Phe Asn Asn Ala Ala Ile Ile Lys Gly Ala Ile Asn Trp Asp Leu 65 70 75 80 Met Pro Gln Ile Ser Ile Gly Ala Ala Gly Trp Thr Thr Leu Gly Ser 85 90 95 Arg Gly Gly Asn Met Val Asp Gln Asp Trp Met Asp Ser Ser Asn Pro 100 105 110 Gly Thr Trp Thr Asp Glu Ser Arg His Pro Asp Thr Gln Leu Asn Tyr 115 120 125 Ala Asn Glu Phe Asp Leu Asn Ile Lys Gly Trp Leu Leu Asn Glu Pro 130 135 140 Asn Tyr Arg Leu Gly Leu Met Ala Gly Tyr Gln Glu Ser Arg Tyr Ser 145 150 155 160 Phe Thr Ala Arg Gly Gly Ser Tyr Ile Tyr Ser Ser Glu Glu Gly Phe 165 170 175 Arg Asp Asp Ile Gly Ser Phe Pro Asn Gly Glu Arg Ala Ile Gly Tyr 180 185 190 Lys Gln Arg Phe Lys Met Pro Tyr Ile Gly Leu Thr Gly Ser Tyr Arg 195 200 205 Tyr Glu Asp Phe Glu Leu Gly Gly Thr Phe Lys Tyr Ser Gly Trp Val 210 215 220 Glu Ala Ser Asp Asn Asp Glu His Tyr Asp Pro Gly Lys Arg Ile Thr 225 230 235 240 Tyr Arg Ser Lys Val Lys Asp Gln Asn Tyr Tyr Ser Val Ser Val Asn 245 250 255 Ala Gly Tyr Tyr Val Thr Pro Asn Ala Lys Val Tyr Val Glu Gly Thr 260 265 270 Trp Asn Arg Val Thr Asn Lys Lys Gly Asn Thr Ser Leu Tyr Asp His 275 280 285 Asn Asp Asn Thr Ser Asp Tyr Ser Lys Asn Gly Ala Gly Ile Glu Asn 290 295 300 Tyr Asn Phe Ile Thr Thr Ala Gly Leu Lys Tyr Thr Phe * 305 310 315 <210> 686 <211> 195 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44477..45061) <400> 686 Met Asp Lys Arg Ala Lys Asn Gln Ile Val Asp Ser Asp Ile Ala Arg 1 5 10 15 Leu Leu Leu Lys Leu Arg Lys Ser Arg Asn Leu Thr Val Thr Glu Leu 20 25 30 Ala Gln Arg Ser Gly Val Ser Gln Ala Met Ile Ser Lys Val Glu Arg 35 40 45 Gly Thr Ser Ser Pro Ser Ala Thr Ile Leu Ser Arg Leu Ala Asn Ala 50 55 60 Leu Asn Ile Thr Leu Ser Lys Leu Phe Ala Glu Leu Glu Met Gln Gln 65 70 75 80 Asn Ser Leu Val Leu Leu Ala Asp Gln Gln Gln His Trp Ile Asp Glu 85 90 95 Glu Thr Gly Ile Thr Arg Trp Ser Leu Ser Pro Ala Gly Ala Cys Pro 100 105 110 Glu Leu Ile Lys Val Glu Ile Pro Pro Met Gly Gln Leu Thr Ile Pro 115 120 125 Ala Ser Ala Asn Glu His Leu Ser Gly Gln Thr Leu Trp Met Leu Ser 130 135 140 Gly Ser Leu Asp Phe Arg Val Asn His Gln Thr His His Leu Gln Ala 145 150 155 160 Gly Asp Cys Leu Ala Leu Thr Phe Ala Ser Glu Tyr Gln Met Arg Asn 165 170 175 Pro Asp Ser Gly Gln Ser Cys Ser Tyr Ile Val Ala Phe Ser Gln Lys 180 185 190 Asn Pro * <210> 687 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45235..45561) <400> 687 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 688 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45558..46448) <400> 688 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 689 <211> 45045 <212> DNA <213> Escherichia coli O157:H7 <400> 689 accgggcgct gagactgatg acaaacacag cattgcctga tgcgctacgc ttaccaggcc 60 taccagataa ctgcaatata ttgaattttc gagattatgt aggccgaata aggctttatt 120 ccgcatccgg cataaacaat gtgtactttg ccaccaattt gagcgcccct taaggcgctg 180 atgttttttt atccttctcg tgcacattgg gccgcttcag caatcagccg cacatcaggt 240 cgcgaagttg ccgcggtgac cagccagcga catgcagagt taagtagcgc gattaatcat 300 gggaaattgc ctctgcatga gtgagcagat attgctccgc ctcaccggac cagatcccct 360 gatgacgcgc cagaatcgcc gccagtgctt gatcctgaat ctgcgtgagt gacgtcagcg 420 gcaggtattt cccggtatac accagctttt tgccgccgcc gacggcaggc aattcaagcg 480 tggtttcgcc cgcggcattc agcccaagaa tatgtgttac cacttttgcg gcctgcactt 540 ttttctcttc aatcaatttg accgctgcgc gcatgtcgtc ggtattgccg cctgacgtgc 600 ccacgtagtg ggtaaatgca taatgcacat cgtagaaatt aattggcgcg ctgaaatgtt 660 tatcctgcgg tccggcgaag aaattcaggc aaccatctgt cgccagcaag gaagaggcga 720 gagtcaccag tccttcatta ggcacaaaga cgaaaatatc atcgaagccg tgaccgccac 780 tcagcgccat tagcgtatca aatgctgcat cggcggcatt gagataatga atcagtgttt 840 gcggttctga tggatagtgc ttgcgcgcat aactcaattt atcgttgtcg gtatcggtaa 900 tgacgagcag cgacgggtta acgggtccat gtagcgcata atcaatcgcc aacagtccca 960 ttggtccggt gccgccgagg atcagcatgc gcccttgcgg gcgaatcccc atcgtgtggt 1020 tataactacc ttcctgaaga tgatagttgg cgttgaacgc gccaatcacg caggaaagcg 1080 gttcaaccag cgagccttca aaataggttt cgccgtcgta tgccagcagg caatcttgtt 1140 ccatgacctc gttgggaata accacatgcg tggcctcgcc gcctacccac gggaaggagt 1200 agccggggca gtccgggcgg tcggggagtt gcaggttggc ctgaatcaca taacgctgac 1260 ccggctggaa tttgtgctgc cactttttac ccacggccag aatatcgccg caaaactcgt 1320 ggccgatgat gattgggttg gtcgccacat cgtcgggtac ttttttatgg ttttcaccca 1380 gattggcctc tttccaggaa gagaggcaca ggctgtcagt gaccaccgtc gcgaggattt 1440 catcctcctg catttcagga aggtcaaagg tttccaggcg taaatcacgt ttaccataaa 1500 gacgcagagc tgttgttttc ataaaccacc tcatgttgaa cgatggcccc ggcagtcgtg 1560 ccggggcgaa gaatcaggac aggaagccca gcgcattgcc gataatccct aagccaaaca 1620 gggcgaaaat cagccatacc gggttaattt ttttgttgag cagacgaacc atcagtagcg 1680 tcagaccgag cgccagcaaa ccagggcaaa gttgatcgag aatgttctgc acggtcatgg 1740 tgacggtgga gccatcggcg gcatgcgttt gtgaaaccac caacggtacg ttgattgacg 1800 tccatttggt gaccagcacg cccatcacaa acagtccgag aatcgacgcg ccttcggtga 1860 gtttttgcag cacattcccg cccatatcgc tgacgatatt cacccctttg cgaaagccga 1920 gctgtaggcc ataccacttc atcgccagac gcaccgcgtt gaaaataaag aagaacagca 1980 gcgggccgag aatgttgcca gacagcgcca gcgatgcgcc gagcgcggcg gtaatcgggc 2040 gcagcgttcc ccagaccagt ggatcgccaa cccctgccaa tggtcccatc agaccgactt 2100 tgatgccgtt aatggtgccg tcatcaattt ccgcgccgtt ggcccgcgcc tcttccatgg 2160 cggcagtgac gccgatgacc gggccacata cggctggcgt ggtattaaat gtaaccaggt 2220 gaatcatttg ataccaacga gggttttagt gaaaggaggt gaaatcacct gtaagatact 2280 gaaataaaac aggtgatgtc tggatgagcg cttaaagtct atttgatacc gattgtgcaa 2340 taattaatcg tttattctaa aatcggcaaa acttttgata ctgcgatctc aactttttaa 2400 agcgtttaaa acttcattaa atctatatgg caactaacat acgggccagc ctcgccaaac 2460 taacccgctt tagattctac cggatttgat tgcctacttg tctcggtttt ttccaaaatc 2520 tctctgacgc aatcgtctgg catatctaca atcatcaacg cagccaggcg cttcctgcct 2580 tctagttgta ataaatcctg gttttcttta tccagcagtg tcagaaccgt ctctacacct 2640 ttgcgagcaa ggagattggt taactgttct cgttcgtctt tcgtaaggaa tgaaagcatc 2700 tgtgtaagtt gatctccctt atcaccagaa caaccaaaat taccacaaat accaacatcg 2760 tttggtgatt cacccttgcc ctctttaagc cactcaagac taactccttc actttcagaa 2820 attcgtataa ggatactttc tctgggggct ggttgtgttt gtcctccctt gaaatagctg 2880 tttaatgtgt tgatattgat tccccacgct ctggcagctg cacttcttga agggtagcgc 2940 tttgtaagca ttccaatacg ttcaataaca ggttcttttc cctgcgacat aaagatacct 3000 cttggtgctt ttctaaggaa aggtttcttt ctatttatcc aattgaaaaa taaggataaa 3060 agcaaaaatt agccaaaata ccaaaaatac cttgatttgg tatttttggt gatgcattat 3120 ttacccgtgc agatatccgc acgaatatcc gcgcgggtaa ctttttagaa tagaggaagt 3180 atgagtagaa gagaagtttc agatcacgat tggccgcctg aaatcatcaa ggcgcgctta 3240 cacatggctg gcttatcact gcgctcttta tctttaaagg ctggttacag cagggattcg 3300 ctgaaaagcg tattacgtac tccttgccga ccgtatcagc aaataattgc tgatgctctt 3360 ggggtatcgc ctgaagaaat ctggcccagt agataccagg ttaagagcta tatgagaaag 3420 gcgtcatgat atgtatgtca ttgcaaaaga actgattggc gcgcccggaa tgcctgctac 3480 aacaaaaggt attcgccagg cattacaacg ttacgtacaa gggaaaagct gttgttcccg 3540 tcgtcgctca ggctctaaag caactgaata cagcatcgac tgtttacctg aagtgacgca 3600 gcaggcatta cgtgaacgtt atgccctgca actgatgacg caaaaagccg atgaatcacc 3660 ggctccggtg gtgacaaagg ccagacgctc atctgacgtg gttgatgcgg tggaggcata 3720 tcgcggatca ccacaactga tggtcgaacg cctcaatgcc ctgactgaaa accagcgcca 3780 ggtggctgat gcacgaatcg cgatcgtcag cgaagtgatg aaagtcgcgc aacaacccgg 3840 tttcagctgc gcgaaggcta tccggtttat cgttgacaac ctggcacgtt cacagctgga 3900 cgagcgcatt gtggcaatgg ttgagacggc gaacgccaaa aagggaaaca gccgtgcgtt 3960 gagtgaaatc acgctgaagc gatggattgc ggcctttaac aaggcacaga acgccgctga 4020 acgcctgctt ttactggcac cgggtaaacg ccaggaaata aaagccgaag atattaactg 4080 gctgcccgaa tttctggcgc agtatcgcca gtcaaacggc cgaccaatga ccgaggctta 4140 cgaggatttt gtcgctgaat ggcagcaccg gcacgctgat gagccttata tgctcgatat 4200 catgccgtct tatgacacca ttcgccgcgc aatgaagaaa ctgccggaag tggtgaaaca 4260 aaaaggccgg gtgaccggca gtgaataccg ccagcttgag ggattcacgc gccgcgactg 4320 gtccagaatg ccggtgaatt atgtctggat tggtgacggt cacggcatga agctgaaatg 4380 cgcacacccg gttcacggtc ggccatttgc accggaagtg acctttgtta tcgacggtgg 4440 cacgcgcttt gtggtgggct ggagccttga cctggctgaa aatgttttcg ccgtagccgg 4500 tgccatacag cacggcattc gccatcacgg caaaccgttt ctgtattact cggataacgg 4560 ctccggggaa accgccgaca tcctggataa ggaggttgtg gggatactgc cgcgactggg 4620 gattaatcac ccgaccggga ttgccggtaa tccgcaggga cgaggcatta tcgaacggct 4680 taaccgcaca ttaccgatgc gcatagcccg taaataccgc acctatttcg ggaaaggtgc 4740 agatcgcgag acgttacgca aaaccaaccg cgatttacgc tcggcattta ctgccctgca 4800 acagggcaaa cggctgaacg cccggcagca gtcagcgatg cgtgatttac cgtcctggtc 4860 tgaactgatt gatgccattc gtgatggtgt tgagtggtac aacaaccggc cgcacgatga 4920 attaccggtg aagccgaacg gcaagcatta cagcccggcg gagttcagaa aaaaacgcct 4980 ggcggaagag gacacggaaa ttgaatggct gtccgatgtg gaattgcggg acatgttccg 5040 gccgatggtg gaacgccctg taagacgctg tgaaatacgc tggctgaata atatttacta 5100 cgcgcccgag ctgcgtgatg agcatggccg caaggtgctt atcagctatg acattcatga 5160 tgccgaacga attaccgtac gtcgcctgga tggcagcgtg atttgcgagg cggtatggga 5220 cggtaataaa cgcgaagcct tcccggttag cgcggaatac tacaaacagc agcaacgcct 5280 taaaggcatg cgtaaacgcg cagaggaaaa aatccgtgat gccgaggatg aggttgtcaa 5340 cgtgctggag cacaagccgc aggagccctg gctggaaaac atctatcgcc cggtaggtaa 5400 tacggtggcc gttcagcaac ctgccattga tgatgagcct gatgaagaat acgagcgcaa 5460 tttccagcgg ggattgcagt tgctcgaagc gaaattaaaa gaaaatgacc cgctggcctg 5520 aaataaaaaa taacccgagc ggcgactcag gttatttgat taaacaaggt atcaaatgag 5580 aggttaataa tatgactgat attaacgatg taatcaagac cattgatgaa cttattgatg 5640 gcggcgtact gacgcagtat gccatcgcca gagaggcggg aatttccgac ggcacattat 5700 cggctttccg caaggggaaa tataaaggcg ataacgccgc tgtggctgct tccctgcgtt 5760 cctggtatga gaactggaat aaacaaagcg cactgccgga accgccgcag tttgtggaaa 5820 cgcagacagt tcaggagctg cgcgcactgt ttcaggcggt tcgcctgatg ggctgtatta 5880 acgtcattgt gggcgtgccg ggggtaggta aaacggccac cgcccgtaat tactgccagg 5940 agcaaccaaa cacctggatg atcaccctgt cacccgcgca ctccagcgtc acggagtgtc 6000 tgctggagct ggccgatgcg ctggggattg attacacccg cgcgaacaaa ggggcattat 6060 cccgcgccat ccgccgtcgc ctgatgggaa cgcgtggact ggtgattgtg gatgaggcgg 6120 atcatcttgg tattgacggt ctggagcaac tccgggcaat tcaggacgcc acggggatcg 6180 ggatggtgct tattggtaac ccgcgcggat tgtttaaagg tggacgccgc gcctttgatg 6240 atttatcgcg cctgttcagc cgtcttgccc gtacaaaaca acttcgcaag gccaaaaagg 6300 cggatgtgct ggccattgcc agggcatggg gtatcagtgg tgaggccgag ctggccgtca 6360 tgcaggctat cgctgaaaag ccgggagcgt tacgcgttct gacacatacg cttaaccagg 6420 cgtggctcac cgccagcggt gaaggtgcgg cgctgacaga aaaacatatt aatgcggcct 6480 ttaaagaggt ttataccaac cctgaattac tctcacaggt gtgattatgg cggtatttta 6540 tattcctgat atttacggac gcttttacct ggttaatttc gataacgtga aggtgatttc 6600 actggccgaa aataaagaat gtggcgattt actttttgaa tttaatgacc gcacacgaat 6660 ggtgatatct gccggacttg atcgcgaagg tgcgacagac gtttacagcg gaatatgccg 6720 ttctgttggt gcgaaacaag tcagctaaat gaggtgttat atgaatatgc aatcctgcgg 6780 taacaaaatg aatttattcg actccctgaa cagcgcgcgc cgtctgaccg aacttgccgg 6840 tgcggtactg gaacgcagta agcgctaccc acaacgtttt gcactgaaaa ccacgccgcc 6900 ggtaggcaac gtgcagggaa ccggtgaaat tgaaatcacc atacagacca acggcctgcg 6960 ccgccgtgtg aaggccaccc gcatcagcgg ctgcacggtt tactgggagg tgtgaggtga 7020 aaaaaaatct cattgcatgg gcgtggtcga gtggtcttat tgagtttggt tacgtcctgc 7080 cggaaggtgc attgccgata gttgccggaa agcctgccac ggtacggcat gtgattgagg 7140 ttatggcgcg tcatggacgt gatgaacagg agcagttact ggttccgggg ataccggaag 7200 cggtgacgga ggaagaagcc tttaatgcca tgattcggtt ctgccgtgag gtcagacgcc 7260 gggtcagtta tccaaacaga acgaggacca gagggtgagt aaagtcgtac gcattatttt 7320 cgaatacaag gagcacgtta tccataaaaa cgctgatgga acagtgcgca tgggggtaag 7380 tctggacata cgttcaaccg ggataaagca gaaaggtgat ggacccgcca tgatttttgg 7440 ggtggttatg ctcgcggaaa gcagagactt tgctgaactt gtggcaatga aagccagtgc 7500 gctcatgaaa gatatgagca tgcgttccgg ggttattaaa ggtaatgaat ttaatcagca 7560 ggggtaattc catgagcaaa gtacgcgtta tttttgaatt taagcatgtt tcgcatgacg 7620 aaaaaccggc aggcaatgac tgtgttgaag tgcatgaaaa gattggtgtg gatgtaaaaa 7680 cagaacgtga tacgaataac aggccgacgt cactctgtga cgtttatgca agtattctcc 7740 agtatcacag ccctgaaatt attcagtttc tctcagcgga atttcaggca tctgtacagg 7800 cttttggggc ggatgccatc attaaacgcc accgcgtgca taaagcatca ggcacactgc 7860 aataaggaaa aacaaaatgg caaaacgcgt tacaaaatta aaggccgcag cagaggcggc 7920 accgcagacc cgtgaagagg tcagccgcga tatccgcacc ctgggcgata ttcagcgaga 7980 ggcgctgcgc ctggaaacag cgatgaatga tgaagtggca gaaatcaccg cccgttatac 8040 gccgcagatt gaaaacctta aaaaagaaat caaagtgctt tttaagggga ttcaggactg 8100 gtgcaaaacc aaccgtgatg agctgacgaa cggcggcaaa accaaaactg ccaatctgac 8160 caccggaacg gtgtcatggc gactggggaa tccatcatgc agcgtcagtc gtgatgtgga 8220 aggtgtgatt gaaatgctgc gccgtatggg ccttgagcgt tttatccgca cgaaagagga 8280 agtgaacaag gaagcggtcc tggcggagcc ggatgcggtg aaagggattg ccggtattaa 8340 ggtgaataaa ggcgctgaaa gtttttatgt cgagcctttt gaacaggacg ccggactgaa 8400 taaataacac cgcattaatc aattaaatat cacttcgttt taattatggc gctcgcgtca 8460 ggggactgcc tgcgcctgta aactgaaaat aaggaacagg atatatggca tatttttatt 8520 tcaaattaga ccgtgtgcag acaaataaat atttcaccaa atatcaacag actgttttac 8580 cgctacgcaa cagtattctt cgggcattac tgaaaaatac aggcgctgcc ggattgcgct 8640 taaagccgtt tgccatggac gtaatcagtg agttttattt ttctggtgct ctgcctgcgg 8700 gctggcgtaa gcgcgatgat gtggctttta tcggggacgg accgtgcttt attgccagac 8760 ctgatgagtc atgccctgaa ggtccggcga ttgccgcaat gattgaaacc gctgaacgtg 8820 agttaagaaa gcgtcctgat ttccttgtct ggctctgtga aaagctgggg gtaatgagaa 8880 tcccctccat gtttaacacg gactcctggt ggaccccgtc gctctcccgt gatgccctgt 8940 gcgtggtgtt taaagtaggc gcttatggca gggaaataaa agggtgtatt cctgaagaat 9000 gccaggaaat taaacattct gaatatgtgg cgctgacgga ggaataattc atgattgatg 9060 caaaagtgct tgaaggggtt aaaaactggc tgagtattta cgggcgtctg acctgcggca 9120 ttctggctga aaaaatgaat atgccgccat cctcgatggt ttattttttg cgtgatgcgg 9180 tcgatgccgg ggtgctgacg gaatgtaacg gtttttatga tattccgcgt ccccgcccgg 9240 tgcagccggt tcgtcgcaaa tgcagccagg aaggtgcggc tgatgatgtt cagtggtgca 9300 gcttcagaaa atccctgccg tggattgagg ggcatgatat tccgtcgatg gcgtgggaat 9360 ttgctcaggg cgtactgacc tgcgaaaccg tttatgtggt ggctgaagtt gatgagcagg 9420 ccatgaaaga aggcgtgccc cagtttgtga tggcgtatat cgacattcgc ctgggtgtca 9480 ttatctgcgg tttaagcggc tggaatatca ccgaacatgt tctgcgttac ctgattgttg 9540 accggacggc tgcacctgcc gggatatctg cggaggtggc gtaatgttct ttaaaacatc 9600 aaacccttcc gcgctggccg cgtggcaaaa atatcagcag gactgccaga aagttaagga 9660 tgaggcaaaa cgccttgagg ccgtgctgaa tgttgcgtgc cggtcggtat ttgtatccgg 9720 tatcagtggc ttttgtttta aagggctgcg ctttatggat gacaaatatc cttttcatcg 9780 cgacttatgg cgaaaaccga ctgcgtcgaa tggctggagc tgcacaccgc gcacatcacg 9840 tattcccaaa gccctgcgcg ttgcctctga cgaacttaac agtctgtggc gtgaatattc 9900 gcccgtcacg tatgccagaa ccgatgcact gttgttctgg ctgggtattg acttctcagc 9960 aatattgcat ggtcccgtga agtggttctg cgttgacgat gttatttacc ttcagtgcga 1002 0 agatgattcc gcaaaacgga aaatgaccga aattctgtct gatgagtttt atgctgccga 1008 0 aaagcgagtc ggggggtgat gcatgatgaa attacaaccc atggggagaa aaggccgtgc 1014 0 acccgctcat gttcgcgcat ggacacctga agaagatgcg ctgctgattg cgctttatcc 1020 0 atccaccccg gttaaggata ttgctgtcag gataaaaaga agtttctggg gtgtacataa 1026 0 ccggattgtt ttattacgcg gtacttaccc ggagttgctc aaatgcaaac gcctcagatt 1032 0 taaacctgat gaagataaat ttatccgaaa aaatgccagg acgatgaccg gtaagcaaat 1038 0 aggagaatat ctggggcgag accgggattc tgtccacaat cgggcgcgat atattggcgt 1044 0 aagcatgaaa aaatacggag aattactgcc ttttacccgc atacctgacg atgatgttca 1050 0 tcttattcgt gaattacggg atgctgaatc accacggcgt cttaccttta gggaaatcgg 1056 0 cgagaaattt gaattatccg agggcacggt gagttttatt tatcaccgtc gtcggactgc 1062 0 cgaagatgtt gtattacggg agttaacgac atgataagga gacttgtttt tttcgcaatt 1068 0 atcgttcctg tgtggggggt tggttttata tttgcggtta caggaaatct gtccatgatg 1074 0 ccggatatat ggttctttat caggatgtcg ctcttcctgt ttattatgaa tcttcttatc 1080 0 gacatatata tccgtattac tggaaaacat aaatgagaaa aatcacgacc ttgtcagagt 1086 0 tacaggagat gaatatgagt attgaattaa gatcgtctta tgaatatcgt aaaattctca 1092 0 tcgccggagg catgaaaccg gaagatgcag aaaaaatcgt ttcttttatg gataaagaat 1098 0 gtgacaaacg ggatatgcca gaaattatta tggatgacat gattctggat tcagccgtgg 1104 0 cgttaagtcc gttatggatt gtgcattctc ttgctgaaat tgccaaaggc accgataaac 1110 0 aggcagctgt tgctgccctt cagacgctta atgaaatgcg tatatctcca cgcccgacat 1116 0 taatacatat gattctgtcc agcatggagg ataaagcaaa tgaatagtct acccgctgga 1122 0 tgggcgcggc cactaatggc caggaagcat cattttttta aaacaggcga aaatatcagt 1128 0 atatgtggac ggtggttata tctggctcat aatcgcgagc cggatacatt tgaaagccct 1134 0 gatgactgtg ccgaatgccg cagaagagtg aataaggaga aagataatgg acaatagttc 1140 0 tctgttgttc tggtgcttat atatcacatc ctttttcggc gcatttgtta ttacccggtg 1146 0 gttatgtcga aaaatcatct gcttttttga taaaagacat ccggttgaac gggcggctga 1152 0 tgcgctcatt cagcaggcca ttgtgttata tagcggtgag tttttctgcc ggataacaac 1158 0 cagagatggc tggcacataa tgattattcc accaacacac catgcccggt gggatgaggc 1164 0 agaaaaggct ttccatgtcc gtaaaaaggt aaatacggta tgagaggaaa actgatatcc 1170 0 gccattcatg tggcaaagcg cgagcttgcc ctggatgatg agacttatac atccgcgctg 1176 0 ctggcagcca ccggcaaaac cagctgccgg gatatgtcac cggatgagtt atcccgcgtg 1182 0 ctggatgttt tcaaaaaacg cggttttaaa gtgcgtcaga acccggttaa ccgggcctta 1188 0 aaaccgggta cggtgaccgc caaaattcgc gccatctgga aggtgatgca ccggcagggc 1194 0 tttatcaccg atggtgcgga aaccgccctt aaccgctggg tgaaatcgca gacggccgcg 1200 0 cagaacggcg gcgaaggtgt ggcaaactgg cagtggctgg agcaacaccc cgccctggcc 1206 0 tcagatgtgc tggagcgtct caagcgatgg caccgccgca aaatgctggc cgcgatggga 1212 0 atgcccgaac gcacgctgat ggggtatgac gccgtttgca ggcagtatga aaaatcactt 1218 0 ccccgttaac cccaaatccc gccacaacgc gggattttta ttttaaactt accgggaacg 1224 0 cgagaaccgg aggctgatat ggcagaaact cagatgagca tgtttggtgg tgacagtgag 1230 0 caactgcacg cccttatcga ccgccttgat gacatccctg atgatgttct caaaaagaac 1236 0 tggccgcgga ccctgtcaga actggttgaa gtcaccggcg cagaacttca gcgtcagggg 1242 0 attgagccgg tactggccgg taaactggca cgcaaggtgg ctgcggctca ggcagcctat 1248 0 atgggcggac ggggttatta cctgccggtc ggggaatctc tctttgccga gctgcgaaac 1254 0 aatgagatat tttcgcgctg ggaccggggc gagaaaattg aatcccttcg ccgccattac 1260 0 cggatgtcag aaacccagat ttataccgtc atacgcgaac agcgccgtct gcatctggca 1266 0 agaacgcaac cgccactttt ctgatattcc gcaaagcctg ccgcctctcc ttcaccgtta 1272 0 cgctgactca gagaacatca tgagacagcg taacaatgcc aaaactcccc gcaccactgc 1278 0 gtaaaaagct gattgccctt gttctggccg gtgccgggac gttcacgatt gccacgcatt 1284 0 acaccggtta ctgggaaggg aaagaaaact ccacgtatat cgatcccacc ggtacaccca 1290 0 ccatctgtta cggccatacc ggcccggatg tgaaaccggg tatgaccctg acagatgaag 1296 0 aatgcctgga actactggaa aaggacatga aatgggcctt tgcggccatt gatcggcgtg 1302 0 ttcaggtgcc gcttacccgt ggtcagacgg tggcgctggc ttcgtggatc ttctgggccg 1308 0 gtgaaacgaa ctttcgcaac tccacgcttc tgcgcctgat caatgccggg cagatgcccg 1314 0 cgtcctgtaa gcagtatatc cgctggattt attcaaaggg ggtgaaactc cccggccttg 1320 0 aggcccgccg ttcggcggat gaatggttat gtcgctacga cttgccgaaa gtctgaaccg 1326 0 cttctggcga ccgctcatga tagcgctgct gtgtgcggta ctgctgttac ggggtgtcct 1332 0 gtggctgcgg tgaataatgc cttaccggcc ctgattgccg gggcgtgcat ggcggcgctg 1338 0 gggattatcg ctgtactggt tgccgctata tggggaatgc accagaagac gcagcgcctt 1344 0 gaagacaata atcaggtgct tgtgcgtgag cgggatgagg cgcgtcaggt gctggcaaat 1350 0 cagcagcaca ccctgcaact catttcacaa atcagtgagg cggccacgaa tgaaaaacaa 1356 0 cagaacattc agcacagcga ggggcagcag agcgttgtcc gccggtcgct ggcagcagtg 1362 0 cctgcggcct ctgcccctgt tcctgatgat gtggctgatc gggtgcgccg ggccgtctgt 1368 0 gaaatacgtg cctgtgaagc cggtgccgat ccccgctgaa tggctggctg actgcctggt 1374 0 ccctcctgcg ccggagccgt tcacgtttgg ggcatcggtc acttacaacc tgcaactgct 1380 0 ggcggtgatc aagaactgca acgtggacaa ggccagtatt cgtcgtctgg agacgcggcg 1386 0 acaacatgaa tttactgata tggccggaac gcctgctgtt ccggcaggaa aaacgaagta 1392 0 aggaaaaggt atggatgatt cagatcgtgc tcaggctgtg atggagcggg gatcagaacg 1398 0 cgccctttgt aaccggctga cacgtaagcg ccaggcagtg gatacgccgg gcagacgtgt 1404 0 ctgcgcggac tgtggcggag agatccccgc cgcacgtctt gttgctgtgc cggatgccat 1410 0 ccgttgtgtg aactgccaga acatcatgga ggcccgtcat gtgggtcagc atcgttaaag 1416 0 attatgttgt gccgatcctt tcggcgacgg caaccgctgg cgggatattc atggcgctga 1422 0 tgcgcaaaac gtttgtcccc cgcgaggcct ttgaaaaact ctccgaccgc gttgagaagg 1428 0 tggaaacccg cctgtcgtca ctgccgacag aagccgaggt caaccgtctg aatgtggaaa 1434 0 tcgtgaccct gcggggtgaa ctgaaaacca cgaacgccac gctccgctct gtctcctatc 1440 0 agaacgaact gctgctggag caggctgtaa ggaaaaaaac gcaatgagtg atttcattac 1446 0 tgaagatcag cgtctggtca ttctgcggtc gctggcagat tacaacggtg aactgggtga 1452 0 atccgtgctc caggactgtc tggatgatta cggccaccgc gtgtcccgcg acaccgttca 1458 0 cacccacatt gcctggcttg ccgagcaggg actggtgcgc aaacgcgttc tgattaacgg 1464 0 ttatttcatc gcggaactga ccggtcgtgg gcaggatgtg gcggaaggcc gggtctgcgt 1470 0 tccgggtgtg aagaaaccac gcgcaagggg gtaacgatgg acaagccgac gcgtggtcgt 1476 0 gtacgcaagg tggatttgct ccccgacagc atccgtaagc cgctgctgga aatgctgcgt 1482 0 gaaaaacgtc tgacgcaggt ccagatccgt gaggaaatca accgtctgat ccgtgaggcg 1488 0 ggcctgccgg aagagcagca gctttcaccg gcggccatca gccgggaagc ctcccgtaat 1494 0 gagctgattg cccgtaacct gcgtgattta cgcgagcaga caaaagccat gatggccgaa 1500 0 ctgggggaca agccgaccgg tgaaaccaca gcgctgattc tggaaatgtc ccgcgccctg 1506 0 atgtaccgcc gcctgcgtgc cgcgaccgaa tctctgaaca gcgacagcga cgtggatatg 1512 0 cgcctcatca aagacatcct cctgtcagca cagcgtgcgg aaagtgccgc cgagcgcagc 1518 0 attaagcgtg aaaaagaaat ccgggccgca tttgctgaag agatggcaaa cgcggtcacc 1524 0 gacgagctgc gcggcgtgga cgggatgagt gaacagcttg agtcccgtat taaggggatt 1530 0 ctgttgggta aagcctgatg aataacgccg aagaactctc acccttactg acgaataccg 1536 0 tctccacccg caaaattgat ctggccggtg aaaaagccct gctgggcgtg gatgtgccgg 1542 0 acagccttga tttgcccggt gatatgccgg tgtttctgga ttatcaggcc cgctggtttg 1548 0 aggatgaaag cgaggtctgc atcgcggaaa aatcccgccg caccgggctt acctgggcgg 1554 0 aagccgggcg taacgtcatt accgctgcaa aaccgaagcg gcgtggtggc cgcaatgtgt 1560 0 tttatgtggg gtcaaagcag gagatggcgc tggaatatat ttctgcctgt gcactgttct 1566 0 cccgtgcctt taaccagctg gcagatgctg atgtgtatga gcagaccttc tgggatcggg 1572 0 ataaaaaaga agaaattctg acctacatga tccgctttcc gaacagtgga ttcaaaattc 1578 0 aggcactgtc ttcccgtccg tcaaacctgc gcggccttca gggggatgtg gtgattgatg 1584 0 aagccgcgtt ccacgagtca ctggatgagc ttctcaaggc ggcaatggcg cttaccatgt 1590 0 ggggcgcgcg cgtgcgtatt atctccacgc ataacggcgt cgataatctg tttaatcagt 1596 0 acattcagga agcccgcgaa gggcgcaagg attacagcgt ccaccgcatt accctggatg 1602 0 atgccattgc ggacgggctg taccgtcgta tctgttatgt caccggccgc gaatggtcac 1608 0 cggaaagcga gcagaagtgg cgtgatgatc tctacaaaaa cgccccgacc cgtgaggatg 1614 0 ccgacgagga atacggctgt atcccgaaaa aatccggcgg tgcctatatt cctcacgcgc 1620 0 ttattgaaat ggcgatgctc cgcgacatcc cgattctgac gtttgaagcc ccggacgact 1626 0 tcatcagccg tgccgcatgg ctgcgtgaat cggaagtttt aacctggtgt gaagaacatt 1632 0 taaaaccgct tttagaggcg ttaaatcccc gttcccgctt cagcttcggg gaagactttg 1638 0 cccgcaccgg tgacctgtcc tgctttgtgc tgctggaaat cactgaatcc ctggcaaaac 1644 0 gcgaggtgtt tcgcgtggag ctgcgcaacc tgccgtatgc ccagcaggag caggtgatga 1650 0 tgtacatcct gacccgcgtt ccggcgctgg tcggtgcggc gttcgacgcc accggtaacg 1656 0 gcggctatct ggccgaagcc gcgctgctgg cctttggccc ggacatcatc gactgcgtga 1662 0 tgttatcgcc gaagtggtac ggtgagtgga tgccaaaact gaaggccgag tttgaggatc 1668 0 agaatatcct cgtcgcccgc catcagacca cgcttgatga tttgcgccat gtgaaggtgg 1674 0 tgaacggtat cccgcaaatc gacaaggggc gtacgaagga ccagaacgca acggctgtga 1680 0 acgcccgccg ccatggtgat tttgccgtgg cgctctgtat ggcaaaccgg gcgtcataca 1686 0 tggagggctt catcctggat gaatcagcct gtcaggcgct gccggagcgg tcgcgggcaa 1692 0 tggagggcgg ttatcgtgat gacgatgagg catatcatga atttgatcgg gggtgctggt 1698 0 agtgggacgc ataattgatc ttgacggaaa acctttctcc tttgacccgg agatgcagag 1704 0 tgccgtgctg gatattccgc agattgccag ccgttatatt gaacatccgg cctcgggtat 1710 0 caccccgaac cgggcggcgc agtgccttcg cggggctgaa cgtggcgatc tgattgccca 1716 0 gtccgatctg gcggctgaca ttgaagaaaa ggatacccac ctttttgcag agctgggcaa 1722 0 gcgacgtctt gccattcaga gcgtgccctg gagtattgag ccgccaccga acgccagcgc 1728 0 gaatgagaaa aaggacgcgg aaatgctcga cgaatatctg cattccgccg actggtttga 1734 0 tgccatgctg tttgacgcca cggatgccat cctgaagggc tattcctgca tggagattga 1740 0 gcacgggatg ctcggtaaaa tgcacatcat ccgcgccatc cgctggcgtg acagcgggca 1746 0 tttctgcctt aacccggatg atttgagcga actgcggctg cgtgacggca gccatgccgg 1752 0 ggtggcgttt cagccctttg gctgggtagt gcatcagtca cgttcacgca ccggttacgg 1758 0 tggtgcgacg gggcttgtca gaacgcttat ctggccgttc attttcaaaa actattccgt 1764 0 gcgcgatctg gctgaatttc tggaggtgta cggcctgccg atgaaggtcg gtaaataccc 1770 0 gtccggggca acatcggagc agaaaagcgc cctgatgcgg gcggtgatgg atatcgggcg 1776 0 acgtacaggc gggatcatcc cggccgggat gtcgctggag tttcaggtag ccgcgaacgg 1782 0 tcaggccgat ccgtttgaaa ccatgatttc gtggggggag cgttccatct ccaaagctat 1788 0 cctcggcggc acgctgacca cggaagccgg agacaaaggc gcgcgctcac tgggtgaggt 1794 0 gcataacgag gtgcgccggg aaatcaggga ttctgattta cgtcagctgg ccgccacgct 1800 0 gaaccgcgat ctggtgtatc cgctgtatgc cctgaacacc gcccacgcca tagatatccg 1806 0 tcgcctgccg cgtatctgtt tccagacaaa agagccgggg gatatcacca aaatcaccag 1812 0 tgcggtgatg cagctcagta cggggatgga tattcctgat ccctgggtac gggaccagac 1818 0 cggtattcca cagcctgccc ccggtgaagc catcttccgt gtccgtcaga gtggcaatga 1824 0 acctgctcag acagacaaag agatgccacc ggaaaaacag gagaagacag agcagacggc 1830 0 gctgtcagcc cgactgccgg aagcgaaaag cagcccccgt gatgaactgg acgatatggg 1836 0 ggatgcggtg cctgcccgcc ggttacagga cgctatcgac ccgctgctgg agccggtcat 1842 0 tgatgccatc agaacgcggg ggctggcgga tgcgctggca gacctgcctg ccctttaccg 1848 0 tgaaatggat gattcccgcc tgatgacgct gctcagtgat gccatgtttg ctgcggaaat 1854 0 gaaggggatg ctggatggca caggggattg atttaggtta tgccgccacc cttccctcaa 1860 0 aagaggcggt ggcatacttc cgcgccaaag gggcgcatat cagctggaac tggttcgaaa 1866 0 cagacgcaga tgttcatgcc cgatcgttca cggcggcaaa agcggcacgc ctggacgtac 1872 0 tgaccacact acaggcggaa gtgcaacggg ccattgatga ggggatttca cagaaagcat 1878 0 ttatccgcac actgacaccc cgcctgcaaa agctgggatg gtgggggaag cagattgtgg 1884 0 tggacagcgc cggtaacgca gaagaagtac agctgggcag tccccgccgt ctggcgctga 1890 0 tttacaacgt gaacacccgc gtggcttaca atgccgggcg ttacacgcag atgatgaaca 1896 0 acacggacac gcatccgttc tggcagtatg tggcggtcat ggacagccgt acccgcccgt 1902 0 cgcattccac ccttaacggt ctggtattcc gctatgatga tccgttctgg aaaacacact 1908 0 acccacccaa tggctggaac tgccgctgcc gtgtgcggcc attgtctcag gcccgtctgg 1914 0 atgcaatggg gttatccgtt tcatccggtg aggatcatct ctccacccgc aatgttgagg 1920 0 ctggcgtgga taaacagacc ggagaagtca gagaaatgcc ggtgaccaca tattcagatg 1926 0 gcaccagaac catgacaccg gatgtgggct ggtcatataa ccccggttcg gcggcgttcg 1932 0 gcacagacca ggcgctgatc cgtaaactga tcgaggtgaa aagcccggcg ttacgggaaa 1938 0 tggtggttca ggagatgaac aacagcccgg agcggcagct ggcgttccgc atctgggcaa 1944 0 aaaatatcat gaaaacccgg cgcggtggtc acgatatccg cacgctgggc tttatgaccg 1950 0 aaagtattgc gcaggcagtg gaaagccgga caggaacgcc accggcccgc ctgctggcga 1956 0 tgagcggtaa aaatgtgctc catgcggaca gtgtgaaaca tcagaatgac ggtatcgccc 1962 0 tgacgccgga ggatttcgcg cagcttcccg ccatgctggc tgcccccgat gccgtgctgt 1968 0 gggatcatgt ccatcagaac ctgctttaca tcactgaaac ccgtgacgga acggcaaaga 1974 0 ttgccgtcaa tgcgccttat ggtgtgaagc gccagccgga taagctggat gtggtaatta 1980 0 atgcttaccg ggtaaataaa tttgatattg aaaaagcaat agagggcgga aagctggaac 1986 0 tactggaagg taaattgtaa gccggtgacg ggggtcgaac ccgcataaac atatgacccc 1992 0 tgagggttta tgccgcttta ccagttaaga gtacaccggc ctgtatttat tttaatcaga 1998 0 tagttttaag gaggcaacat gtcatccatc gatgcagccg tggtggtgga cgttgcgcgt 2004 0 ctccagcggg tctttgcccg gcttcagttt gtgggtggtg gaaaagacct ggcccgcagt 2010 0 gtggcgtcca gccttctgtc atcgtcagaa atggcgtttg aacaggaaaa agagccggac 2016 0 ggcgaacgct ggcatgactg gtcagatcct taccgcaagt ggcgtacccg taagggaaac 2022 0 atgcccggca aaatcctgac gctgaacggc gatctggccc gacgcctgac cacggattat 2028 0 ggcgatacct gggcgctgat tggatcaaat gagccttatg cggccattca tcagtggggt 2034 0 ggcctgccag gtatgccgcc tggaccggcg gccattggtg cacgtccgta tatgggtttt 2040 0 gatcaggtgg cagagcagga gatcatggac gaaatcagaa aacgctttaa aaaggccaca 2046 0 gaaacgcctt aattgtttaa ggtatgcaaa tgcattacct tacccccttc aggcgcgtgt 2052 0 cgtgattttc taacctgtat ttaacgggct ttaaaatctg cgtgaagcgc ctttgtattt 2058 0 ttcccctgga agcacttcct gaaatcccgc aaaacccgcc ctgaaaattc ccggcctatg 2064 0 ctgccggaat gaagacgaaa aacacgccca aacttgctta tgccattctg aatgccatca 2070 0 gcctgtccgc agacggggac ggtgactggt gtcagatcat gccagccggt cgggtaaagg 2076 0 cccgtgacgg tcgcccggaa aaaccggcgg aaggctggct gatcaaccat gcagccgttg 2082 0 agcgcatggt ctcccgtgtt gtggcgctca atcagccggt gaaaattgac tacaaccacc 2088 0 agaccctgat tgagggacat ccggcaccgg ctgccggttt tgtgatggcc tcaccggaga 2094 0 attttcgctt cagtgaagag cgaggtttcg aggtgcgccc gaagtggaac cctccggccc 2100 0 ttgaacatct gcgtaataac gaattcccct ggttttcacc ggtgattggc tatgacgaga 2106 0 gcaccggcga acctgtcgaa cttcggatgc tggctattac cggtgacccc ggtctgaccg 2112 0 gcatgaatcc tgtcgccgca ctgtcggcgg atgaccttta taacgcctta aaccctcctt 2118 0 taaaggatac ctccatgaat gagcaattac gccagttgct gacggcgctc ggtctgaccg 2124 0 tggctgacgg tgacgaattt acgccggagc tgggcacggc ggcgctgtct gccctcaccg 2130 0 ggatcaaaac ccgtgcggat gcacacgaca acctgaaaac acaggtcgcc agtctgtcgg 2136 0 cagagctgga aaccgcaaaa ggcacaccgg ctggcggcat tattgatctg acgaaatacg 2142 0 tgcccgttga aacgtataac gccctgcgta ccgaatacgt tgcgctgtcg gcgcagcacg 2148 0 gcagcaccac gctggagcag gtgctggaca aggctgaatc cgaagggcgc atcttcaaaa 2154 0 gcgaacgcgg ctatctggaa caactgggcg ggcagattgg cgttgcggca ctttctgcac 2160 0 agcttgacgc ccgccagccg gttgcggccc tgacctctct tcagaccgac accgtgaccg 2166 0 tgccggataa aaagactgcc accgctgcgc tgtcggctga agatatcgcg gccgccaaac 2172 0 tgctgggtaa aaccgaagcc gagttcctga aaatgaaaga ggaaatgcaa taatgcctac 2178 0 cccgattaca ccggcgatga tcacagccct gatgacgggc taccgttctg attttcaggc 2184 0 cgggatgtcc atggccccgt cgcagtataa aaaaattgcg atgaccgtgc cctccacatc 2190 0 gaaatccaac acctacggct ggctggggca gttcccgcag ttccgtgagt ggatcggctc 2196 0 ccgcgtcatc gagaagatga aagcctatgg ctatgccatc gtgaacaaaa cttttgaagg 2202 0 cactgtcgcc attagccgcg atgacttcga agacgacaac ctcggtattt attccccgtt 2208 0 gttccaggag atggggcgcg ctgcggcggt acaaccggat gagctggtct ttgctgccct 2214 0 gcgtgacggg atcagtgcgg cctgctatga cggtcagaac ttctttgata ccgaacatcc 2220 0 ggtttacccc aaagtggatg gctccgggga tgcgcagatg gtcagcaata tgtttgtggc 2226 0 aaaaaccggc tctgtcggcg cacaggctga ttacagcggt ccggcctggt atctgcttga 2232 0 ctgctcccgc gcggtaaaac cgctgattta tcaggatcgc cgtaaggctg aactggttgc 2238 0 ccagaccaaa gtcgatgaag gtcgcgcatt caccgataac gaatttgtgt ttggtgcatc 2244 0 cgcccgtcgc aatgtgggct acggcttctg gcagatggcc tacatgatgc agtcaccgct 2250 0 gacgctggat gcactgtggc acggctggtc agccatgcgc gaatttaccg ctgacggtgg 2256 0 ccgcaaactc ggcattaaac ccacccatat tgttgtcccc acctcgctgg aaaaacaggc 2262 0 ggtgcagctg ctggagcgtg aactgttcgc agacggaaac gcaaccgtct ctaacgagat 2268 0 gaagggtaag ctggagctgg ttgtcgcgga ttatctgtaa acggtgagcc gggcttacgg 2274 0 cccggcccct gcggagggca aatatgaatg aacatcacac tgtggcagca acagatgatt 2280 0 caggtcttca ggtcagtggt gacaattctg tcacggtgct ggcagaagtg cgttgcagtc 2286 0 gttcggcgtt tcgtcgtgcg gggttcctgt tcacgcgtgg acgtcagcag gttgaggtca 2292 0 ccccggagca gcttgcccga ctggaggagg agccatgcct cactgtgcga atactacaga 2298 0 cgtctgctga tgatgcgggg agcgtggcgg gtgtggttca tgcagtggcc ggtacagatt 2304 0 tagccgaagc cgaagccgaa gccgaagccg aagccgaagc cgaagccgaa gccggacagg 2310 0 atgctccccg gaaaaagacc ggtaacaaag cggaacaggc ccgtgcatga attacgccac 2316 0 tgaaaccgat atgcgggcgc gttaccgcga ggatttgctc aggccgttac tggctgtgcc 2322 0 ccgttcggat gagccggaca cgcgcaagct gaaccgggcg ctgacagatg cgtcagccct 2328 0 tatcgacagc tatctgtccg cccgttacac gttgccgctg gaggttattc cggccgttct 2334 0 tgttcagcac tgttgcgcga ttgcctttta ttacctgtgc gatcagcgag cctccgatca 2340 0 ggcgcgtgac cgttaccgtg aagcgctggc ctggctgaaa gatgtcatga acggcaatgt 2346 0 gccggtcggt gtggatacga acggtgcggc ccctgaatcc ggggatttac cacaggttca 2352 0 gtctgatgca gcggtattcg ggcgcaacca gaagggcttc atatgattac ggaaaccgaa 2358 0 caggcataca tcgcccgtat ccgtgagtat ttcgggaatg aactggtgtc tgttgacacg 2364 0 catcccggcg actggagcga cagcgtactg cgcaccatgc tgattaacgc cccggcgatc 2370 0 tacgttgcct ggctgggtgc cggtgaaggc cgtacccgtg gtcgcctggt cagtcactgg 2376 0 gtgttctacg tcatcggcga catgctcaac gggcgtgagg ccagccgtcc cggactgtat 2382 0 cagattgtgg cccggctgat tgccgtgctt aacggcttca gaacagaaaa aacctcaccg 2388 0 ctttactttg aaaaggcggt caacggttac accgaaaccc aggcggacag tggtgcggtg 2394 0 atgtatgcgc tttatttctc ctgcgaggaa atgatcgcac cgctgaccga taccagctcg 2400 0 ctggacgact tcctgcgtca ttacgaaacc tttgtggagc cgcccggtac gccgccgttt 2406 0 gaggcacata ttgatttgcc ggggaacacg acaacggcgg tcgaaccgcc ggaggaactg 2412 0 taaatgaaaa ccatctttat caaacccgcg ccgggacgcc tgattcgtga tcccgacaca 2418 0 atgcgcccgc tggcacagga gggggaggaa aagcccttta cgccgttctg gtgtcggcgt 2424 0 cttgatgacg gcgatgtcat tcaggctgaa aaagccgctg aagaggctcc ggctgtatct 2430 0 gcggatgcaa cgactgcgac agaaaaaccg gtcgcccaac cggcatccga taaggagaaa 2436 0 ccgcaatgat taattttgac gggatcggta atgaccgccg tataccgctg attgaggttg 2442 0 agtttaataa ctccatggct gtcaccggca ctccggcaca gcgtcagtgt gtgctgctgt 2448 0 ttggtcaggc gagaatgaaa gagaatgccg tggacggtgc cggtgttctg gatgttccgg 2454 0 tcaggatcac ccgtgcgtct caggcaacag aactctgggg gcgcggctcc atgattgccc 2460 0 tgatggtggc ggaatttatc gccatcaatc ctgatgctga actgtatgcc attgctcagg 2466 0 ggaacggcac cggacaggca acggctgcgg ccatgaatct gaccggaacg gtcacccgtg 2472 0 acgggattgt ttatgcctgc gtgggggggc ggcgttatac actcccggca ccaaaaggta 2478 0 agaaaggcaa agaactgacc gacgagctgg ccgcgctgat caatgccgat cctgacgcgc 2484 0 ccttcacggc ctcctctggt gcaggaagtg gtgataatgg cgcaggtctg aaagggtctc 2490 0 tggggatcac cgcccgcttt accggtgaat gctccgttca tgatgtgcgc ctgaactatc 2496 0 acgacgggga agcaaccccg gaaggaatac aggtcgctat agcctatccg aaacaaaaag 2502 0 cggctaaccc ggatatcacc cgaagcgtgg cgggtatggg cgatcgccag tacaactatg 2508 0 tcgtcatgcc ctataaggat gatgcaaacc tgaaaatcat cagtgatgag cttctgaaac 2514 0 gctggggacc ggccaaaatg tctgacggcg tgctgtggct ggcacatacc ggcacgtttg 2520 0 gtgaggtgca ggcattcggg gcaaaacgca atgattttct ggcgacctgc acatccattc 2526 0 ccaaagcccc tgaaccggat tacctctggg cagcggcggt ctgtgccacc tgtgcaccct 2532 0 ctctgggagc agatcctgcg cgtccgcttc agacgctggc gcttccgtca cgcatggccc 2538 0 cggctccggc cgatcgtctg acgcgtgaag agcgtaacag tctgctgtgg ggagggattg 2544 0 ccacggtcag tgtggctgcc ggtgatgtgg ttcagatcga acgtcaggtg accatgtatc 2550 0 gccagaacgt gtacggcgaa agtgatccca gctatctgga tgtggaaacc atctacaccc 2556 0 tctcctggct gcgttattcc ctgcgtactt ttatcacaca acgttttccg cgccataaac 2562 0 tggctgatga cgggacgccc gttcgtgccg gtcagaatat cgtgacgccg gagatcatga 2568 0 agcttcagtt aatttcgctg ggtgaagagt gggtggaact cgggctggtc gaaaatctgg 2574 0 acacctttaa aaagaatctg cttgtggagc gtaatgcgtc agatcgaaac cgtcttgacg 2580 0 tgttatgcac gccggatctg gttaaccagt tccgcttcct ggcagcacag atccgtttca 2586 0 ttttgtgagg taaggcatga gcggaaaaca gtatcagggt acggccacta tccgtgtgaa 2592 0 cggtcaggaa tacgagacgc ttgagggggc tacattttct ccgtctggtt ttgaacgtga 2598 0 agtggtgaaa ggcgcgaaag tctatggtta ccgccagaaa ccacgtgaag cgacgctgga 2604 0 ctgcaaattt ccggcaggcg gagaaggttc accagccgcc gatgaaatca acaactggac 2610 0 tgcggtcact atcgagtttg tggcggatac cggcgaagtc cacatgatga cgaaggcctg 2616 0 gagcagtgaa ccggcctcgc ttgacggtgg cggggagatc tccgtgaagt tcgccagcgc 2622 0 ctccagtacc cgtgttcagt gatcaggaaa aataaaatga ccacacgtaa gaaaaaaacg 2628 0 gcagtttccg aggcagccgt gatggaggca atccgggaag cacttgaggg ggctgatcca 2634 0 cgcactgccg ggctgacaga gcaactggca aagggatatg tggatctgct tgatggtctg 2640 0 ccgtttggtg agacccgtga atatcgtgtc acgttccggg aactgacagc gaaagacagt 2646 0 attgacgcag aagcagaagc cgagcgcgtg gtggagacaa acaatggccc gatgctgata 2652 0 gcgtctccgt cgttacgcgg tgttgcactg ctgcgccgtc agattgccgc agtgggagac 2658 0 attgaaggtc cgttgtcacc ccgtcagatt ggacagttaa gcgagcgcga tctctcccgc 2664 0 ctgatggcag cggtcagcct gctggatacc gcgcttgccg gaaagctggc agctgaccgg 2670 0 gggcgatcag gcgcagtgtc gggatcagat tgaagaagcg gcaattatcc tggggatggt 2676 0 gacaaaaagc ggtccggaat gggcgcttaa cctccccctg tcgcaacttt accggcactg 2682 0 ccgacagaca gaaaaaatca tcagaacgaa gcagtaagta tggcccgaaa tctcagagca 2688 0 tctctgatag ttgatttgct cggcaatatc tcagccaaat cccgccagtg gtcacaggag 2694 0 ctgggggcat tctcacgctc cggccaggcg gggctgggtg gcctgggaaa tgctgcccgc 2700 0 cgtgccgggc aggaaacaga tgtactcgga agcaggatgc agcgcacgct ggccggggtg 2706 0 cggggcagta tccgccatgt cacttctgat tttgaccgtc ttcagggcag tattaccggc 2712 0 accatcgggc ggatcagcaa tctttacgga atgctggccg gtggtgctgc tgtatatggc 2718 0 tttaaccggg gatttattcg cccggcagcg gagatggaaa cctatatgat tcgcctgaac 2724 0 tccctttaca aaggggatcg ggcgaaaact gatgatgtcc gcaggtgggc aatacagaat 2730 0 gcgaaggaaa ccacctgggg gctggctggc gtcatgcagg aatatacgtc cagtctgggc 2736 0 tttggtatga gtgacaggga ggcccgaaat tttgtcacca tgcttcagga tcagggtgcc 2742 0 gtgggcggct ggtcactgtc cgatgcacag ggggcatccc tgcaactgaa acagatgtat 2748 0 gcaagaggca gtattcaggc ggcggatgca aatattcttg ccacctacgg cattaatgcc 2754 0 taccgcgtgc tggctgatcg tctgggtgtg gaccagaaag tggtcagaaa acttggtgaa 2760 0 aaagggctgc ttgggccgga cagtattcgc ctgttatttc agacgctggc ggaacaggcc 2766 0 aggggagcac aaaaggacgc aatgaattcc tggagtggcc tgacggccat gatgggtgac 2772 0 gtctgggacc agtttgcccg ggatgtgatg gacagtgggc catttgaaaa actgaagggt 2778 0 aatctcaggg gatttctttc atgggttgac agtgccaaat ctgatggcag ttaccattcc 2784 0 ctggcggaaa gcacggcatc agccatgaac cagggctttg agtatgcccg tgatgcagtg 2790 0 actgggtttt atcaggcgat cagaaaggta cgcgacacgc ttcaggctct gcgggatgcg 2796 0 ggctatggtg atgcgctgga tcgcattggt cagggggcac agaccgccgc gaaatacctg 2802 0 ctgtacatgt atctcgccac ccgtgccctg aaaatggcgc gggctgtcgg aacggggatt 2808 0 atacgtccgg gtgctgcatt gctgggatac ggattatcag cggcggcctt cctgacctca 2814 0 cctttccggc gctctcctcc ggccggaaca ccaccaggca catatcaggg acgagggcaa 2820 0 cgttttataa actttcttac cggggtaaat ccggcagccg ttcagccagt acttgtaaca 2826 0 aactggccca caggaggact gtccggcacc ggcgcgaccg atacatcctc aggcggacgt 2832 0 caggggcggg gccgcaggaa acgcggaccg gggcgcggaa gaccggtcac gcctcccctg 2838 0 ccaccgtccc cagtgccacc gtctccctct tctggtgggg cagggttctg ggggcgcatg 2844 0 atggggcgcg ccggtgggtt actttcgtct gtcggtagcc gcatggggct ggggcgtttc 2850 0 tccggctttt tccgcagtgc cggtggactg gccggccggc tgggtggagg tgccctgtgg 2856 0 gctggcgcga tggcagcccc ggttctgctg gatggcagcg ccagtgccac agacaaggga 2862 0 gaagcggtcg gctctcttgc aggcagtatt gccggtggtg cgctgggggc ggcagccgga 2868 0 cctgtgggga ttgccattgg ttctacggtg ggcagctatc tcggtaacta tctgggggga 2874 0 tggctgactg aagcctggca gaaattacgg ggcagtgatg atgaaagcag tggacaggcg 2880 0 gtacaaaaag cctctgcccg tgtggagctg gttgccccgg aagggtggca ggctcgcagt 2886 0 attgatattg atgacacgtc cggtcacgga ctggatgtga atgtctggaa cggagggaat 2892 0 tatggcctct ggtgacggtc gtggtgcgtt ccgtggtgtg ccgttcctcg tctggcgtga 2898 0 gcagcgcgaa cgtggcgggc gaaacattgt ccgtcgggaa tatccgttac gggaaaccgg 2904 0 tggtgcagac gatctgggac ctaaactggc tgaatttacg ttcagtgtac ttgtgatggg 2910 0 ggatgatgtt cagacacagc gaaatcgtct gcgtgatgcc cttcgtgctc ccggtgccgg 2916 0 ggagctgctt cacccggatt acggcacgtt aaatgtgctg ataaacagct ttgaaagtcg 2922 0 ttataacgct gctgaacagg gcgtggttga gttcaccatt aatgtcacgc cggtaagtga 2928 0 tgataccgca cctgctgtca cacaggacac ggccgccatt ctggagcaga agagtaccac 2934 0 cgcgctcggg aaggtttttg aaaccctaga agcgggctgg acggtgattt ctgacggaat 2940 0 gcacgatgtc caggcaatga ccgaaaccat cagcgataag gtgtccgccc tggaaaatgc 2946 0 cgtttccggc atggggattg tacaggatat cagtgccttt actgccacgt tcacggcgct 2952 0 gaaagggaat gccacggcat tactgacagc accttcccgc atggcctcat cttttgcggg 2958 0 gcttttcagt gccctgatca ccctgccatc gctgccgtca ctgtcttcag gaggcctgaa 2964 0 tacccggccc ggtggcagta tcggccggac gacatccgcc ttctctcagg gaatgccgca 2970 0 actgtacagg acattatctt ccctgcgtta cgtgctggat gagcaggata atccgcagac 2976 0 tctcatcggt ctgacaccgg cagcacaaaa gaatattcgt ctgatacggg cggtaatgca 2982 0 gagtgctgcc gtggtggccc aggcacagac cgtgggaaaa ctgctggatc aggttctcag 2988 0 tcaggaaacc ctgccggaca gtgacgcagc ccaccgtacc tggcctgtct ggctggaaag 2994 0 ttcagttgat cttcagcgca ttaaccgtga cttaagcgaa gcgctcgaac ggcaggtgat 3000 0 gacactgtcc gggcaggggt ataccgccac ggcgctgacg cttcgtgatg ccagactggc 3006 0 actgacagag gatctgaata cacggggagt tcagctaccc ggtgcaacag tagtgactgt 3012 0 acgtaccacc gagcctgcac tggtgaccct gtaccgtgcc accgggaaca gtaccggctg 3018 0 gcaacgtttt gtgcgccgta acggtattgt tgatccgctg ttcattcccg gaggccattc 3024 0 agtggaggtg attagtgagc agcagggttg aactgtatct gggcggtgag attttttccg 3030 0 gctggctgac ggtgagtgtt cgtcgctctc ttgaacatct ggcgggctcc tttgaactgg 3036 0 gggtaatgat gcccggtgta cgccttccgt catccgtccg tgccggtcag tctctggaat 3042 0 tgcgcattga cggtcagcct gtgatcactg gctggctgga tcaggtccgg cagcgcatca 3048 0 gcgccacgcg ttttcagatc acgctcagcg gacgggataa aaccggtgac ctggtggact 3054 0 gttcagccat tcatccgggc agccagtgga ggaaccgcac gctggagcac attgcttcag 3060 0 atttgtgtgc tccgttcggg gtcacggtgc gctggcaggt aaatgatgca acggcagccc 3066 0 ggcccttttc caccttcaca ctggaaaact cagaaaccgt ggcagatgcg ctgacacggg 3072 0 ccgcgagaca cagaggcgtc ctggtaacca gtaatgccgc cggtgaactg gttttcactc 3078 0 aggccggcag tcagcgtggc gacacgctga cgctgggcga aaatctgctg gatttggatc 3084 0 acaacgtgga tcaccgtctg cgccacagtg aataccgtgt acgggggcac gggcgtggtg 3090 0 gtggtcatgc cggggatgca ctgacagccg gaacgctggc cgcacccgtt ggtacggtga 3096 0 cagacagtgc catccaccgt tacagaccga aaattgtgct ggcggatcat gctgttgatg 3102 0 cagacggtgc acgccagagg gctgtccggg aaatgcgccg ggcggttgcc cgctctgtgc 3108 0 gcctgacagc caccgtgcgg cactggtttc gggagaacgg ccagttgtgg gatatcaacc 3114 0 tgctgacggc tgtcacggct ccccgcaccg gagtggaaga gcgtgatctt cttgtctgtc 3120 0 aggtggagtt ttcgctggat gcaaatcacg gcgaaaccac ccgtctgatt ctggcacccc 3126 0 gtgacggctt tattgttccg gcagagccgg gaaacagcgg aagcggaaat gcgggtgacg 3132 0 tggacgcctt cgtgcgggca cagatgaaaa aacaggggat taaattcaat gatgaatgac 3138 0 gaagtcatca gccgccttct ggcccccgtg atgcggggtg ttcgtctgct gttcgggcgt 3144 0 ggtgtactga ccggcacaac ggacacgctg aaaatccaga atgtgcaaat caccggtatg 3150 0 gatggtgaaa cctttgatga cgttgaacgc ccccagcagt acgggcaaat cagcgtcccc 3156 0 ctgcctggtg cggaagtttt tctggcctgt gctggcggac aacgggatca ggccgtggtg 3162 0 cttgtggtgg aagaccgccg cagtcgcccg accggactta ccgccggaga taccggcgtg 3168 0 tatcaccatg aggggcaccg tatacgtctg acaaagaacg gccggatcat tgtgacctgt 3174 0 aagacgctgg agatttacgc cgatgaaggt gttcaggtgg atacaccgga ggctcacttt 3180 0 accggtaatg tcacagtgga taagaacctg catgtcaaag gcaatgtgtc cattgacggc 3186 0 accggaagat cacaggggac gttcacgatg tccgaagcgg ttattgccgg gatcacctat 3192 0 tcaggtcatg tgcatcacga taacggtgaa ggcagcaaac gcggaggccc agagaatggc 3198 0 tgatatcgct gtcgtctggg atcagggttg cggttccctg caactgaacg gcgcagatct 3204 0 tctgacggat aacagcctgc tgactgcggt cattatttca ctgtttacgg acaggcgggc 3210 0 gctggattcc gatgaaatcc ctgacggcac ccgtgaccgt cggggatggt ggggagacag 3216 0 tttccgggag cgccccgttg gctcccgtct ctggctgtta agccgtgaaa agacgctgtc 3222 0 ctccgtggtc agccgtgcac aggcctatgc tgatgaagcg ctggcgtggc tgcataaaag 3228 0 cggtgctgcc acatccgtgg tatgtcatgc catgcgtgtg gggcatgctc gcctttcgct 3234 0 ttccgtgaaa atcaccctgc cggacggaag cagacatccg atgatttttt atgctgatat 3240 0 gaagggggaa tgatgcctta tcagccctta ccactggcgc aactgatcac acagacacaa 3246 0 caggatatca gccagcgcct gcccggttcg cagccgggcg tgaatgaaac caccctgaat 3252 0 gccattgcgt atgcactggc gggtctgtca gcacaggagc atgaacatct ggcctggatc 3258 0 tcccggcaga taattccgac agaagctgat gaagccgaac tcctgaaaca ctgcgcattc 3264 0 tggggtgtca tccgtaaacc ggcttcccgc gctgacggac cggtacaact gatgctgacc 3270 0 acggatgcag ggatcacgga aggcgtactc cttcagcgaa gcgatggggt tgtgtaccgc 3276 0 atcaccggct ctgcgaccgg aaaagccgga acactgaatg ttaatgtgga ggcggaaagt 3282 0 gcggggcgcg ctggaaatac cccgaccgga acccgcctgt cctttatcac gccacaggcg 3288 0 ggcatcaacc agacagccac ggtcaccggc acgggactca ccggtggtgc ggatgtggaa 3294 0 acggtgccgg agttgctgtc caggctggta ttccgggtac agaacccgcc atcaggggga 3300 0 acacagtatg attttgaacg ctgggcacgg gaagtaccgg gcgtgacgcg ggcatggtgt 3306 0 aagcctgaat ggcctgaggc gggtagtgtt ggtgtgactt ttgttcagga taataaccct 3312 0 gacattttcc ccggagaagg tgatgtgaag cgggtggcgg attatatccg cagtcatgat 3318 0 gatccggcga cgggccagcc cgttggtcag ccacttgggc cgacaatcag cgtgtttaag 3324 0 ctgaccaata agccggtggc gtttgagatc aggattgtac ccaaaacgcc ggaaaatcag 3330 0 gctgccgtaa aacaggcatt aacagacctg ctttataacg aatcgcggcc gggtggactt 3336 0 gtattgcctt catcattctg gcgggctgtt gcaggggtga aaggactgga ggattttgaa 3342 0 gttcgcagcc cgctgaagtc cgtgatggcc ggagatacag agttgctgac cgtgggggaa 3348 0 atcacatggc tgtaaccctg accccgcatc agcgcgccct gttgcagttg ctgcctgacg 3354 0 ggctggcatg ggataagcgg ccgtcatccg ttcttgcggc tttgtgcctg ggcctcagtc 3360 0 attccacgga gcgtgtttcc tggaccggta accagatgct ggcagaacgt tttcctgatt 3366 0 catcccgtct gctgctggaa gactgggagc gttatctggg gttaccggaa tgtgatatga 3372 0 ccggcgcaac cattcaggag cgtcagcgtt atgccgggaa taaataccgg atgaaaccct 3378 0 ctcttaaccg tgaattttat atccggtttg cggcagagtt tggttatgaa atagatattc 3384 0 agccatcacc ggattcacag tgggtcagta ttgtcacgat taacagtgaa accggctacc 3390 0 ggaatatgaa tgtgctggat gatattctca cgccgctgcg tatttatgaa ggcggtgcgc 3396 0 tggaatgtat tctgaaccgt tataagcctg catggcagac gtttatttac gtatatgcaa 3402 0 acagtcacga agaggagaat atttaatgtt ccatgttgat aataattccg gcgtggcgaa 3408 0 tatgcctgcg ctggcaccgg cgcagagtaa taccaccacc tggtttaccg aaggtgacgg 3414 0 acaaaaaggt atcagctgga ttggtcagga ctggctgaat attctccagg ccgaactgct 3420 0 gaatattctg gctgaagcca gtattcagcc ggataaggcg cagttaaacc agcttacgct 3426 0 gtccattaaa gccattatcg ctgcgaatgc cttttcccgg aaaaacaacc tgaaagaaat 3432 0 tgctgatgcc ggtgcggaag cccagcgtct tgcccgtggt tatcttggtc ttggggcgct 3438 0 tgccacaaaa aacagtcttg gtcccggtga cgttaatgct ctggcgaagg atcagaacct 3444 0 tgccgacctg gagaatgcgg gaaccgcccg taataatctg gatgtttaca gcaaaagcga 3450 0 aggtgataac cgttacctgc gcagggagca gaacggcgca gacattccgg ataaaggcgc 3456 0 ttttatcgat aacgttggtt tacgggaaac ggtaaataag gctgctgatg ccctgccatc 3462 0 gggtggaacc gccgtggcag caaacagact cgccacccca agaaatatta atggtgttcc 3468 0 ttttgacgga acgctggata tcaacatcac gtcaggaatg acgcagtcaa ccgcagatgg 3474 0 ccggtatgta cagaatgttc agcttggagc acagagctat cattcacccg gaggcaatga 3480 0 aatgtcatgg aattacagcg caccttccgg ttgtatgctt tccggaatta acgtgcagga 3486 0 aaccggctcc cggtctgcgg acaatatcgg tggggtctat tatcgcccgg ttcagattta 3492 0 tattaataat gcctggagaa cggtaagttc agtgtaaacc acagaaaagg gtgctgaatg 3498 0 caccctctga attattccgg tttttccggc cagggaatcg cctggtaatg cccctcactg 3504 0 gcaatatcat taaagtgcat ttctttaagc tgtcggatat acgccatcca gcgcgtcagc 3510 0 tgtaatttat tttcatcgct aatcatgtcc agttttaatt ccgttttcca gtcatccaca 3516 0 gtttcgttgg cttcctggag cagcgatgag cggcgctttt cagcaaccgt cttccagttt 3522 0 accggcacct ttgatatcag gccatcagaa aactgccagt taccgtcaat attcacacct 3528 0 tccggcagtt cgtccacttc aacaacagta aaacctgccg gatataaagc agagacatct 3534 0 tcagcaacag agcagataat acccgttaca ggcgaaatac agagtttgta tttctttgtg 3540 0 aaaagcggga tagattcata aaaatccctt ccgtcctcac tctggaaata ctgaacatcc 3546 0 tcaccatagg gtttgtgttc cgggtaatat cgttttacgt taataagctc cattatttca 3552 0 ccttgttttt gttgaaaaga caaaatcatc atatatttat tcagataatc tgttttttga 3558 0 actactgcac ttttatgcgc tggaagctgt tttccacgaa ccatctatca gaaactgaac 3564 0 aggtcgataa tatgcggtta ccgttgcatt accatcacca gcgacatcaa gccctgtaag 3570 0 tacgcatccg tcaggaacct caaaaatatt atattgcatt ccaatcgttg accttgaacc 3576 0 tcttcgaatg ctttgaacat aacgtgagtc agccacagac tgcgtcatcc ccgatgtaat 3582 0 atttatatcc tgcgttccgt caaatgggac accattaata tttcttggag tggcgagttt 3588 0 attcgctgca acagccgctc cgttcgatgg cagggcattc gcggccctgt ttacagtatc 3594 0 ccgtaaacca aggtttcagg gatgccgtat atctgcttta aaaggccttt ccacctcttt 3600 0 ttaaggaagg taaatacatg ctgattggct atatacgcgt atcaacaaat gaccagaaca 3606 0 caggtttaca aagaaatgcg ctggaatgtg caggatgtga gcagattttt gaagataaaa 3612 0 tgagtggtaa aacgacacag cggccgggac tgaagcgggc actgaagaaa ctaaaacccg 3618 0 gtgacacact gatggtctgg aaactggaca ggctggggcg cagtatgcgc caccttgttg 3624 0 cgctgacaga tgaattacag caacagggga taaattttcg tagtcttact gacaacattg 3630 0 atacgtcaac ccccatgggg cgcttctttt ttcacataat gggtgcgctg gcagaaatgg 3636 0 agcgtgaatt aattgtcgaa cggacacggg ctggtcttgc agctgcccgt gaaaggggac 3642 0 gaaccggcgg cagaccccgt cgtctcacgc aggaacaata cgagcaggtc gggcgtttac 3648 0 tggccggggg tgtcagtcga agacaggtgg cacttatttt tgatatcggc ctttcaaccc 3654 0 tttatcgtta ttatcctgcg agcgtttcgg aaaaataaga cgctctcttt gttgggcctt 3660 0 tactgaatta acgcaaaatg gcgtttatcg gtctgtggat atgataattc agtttattca 3666 0 ggaacaggct gattattatg acgtccaaat gggttcaact atcatcaatg cccggaaact 3672 0 ttactgttaa agtttccggt ggtacagcgg catttcttga ggctcccttt cctccggccg 3678 0 aaacaaaagg aggaatgaca tttgctgact gtctcatcag ttttaataca cgggattgcc 3684 0 tgtgggtaag gccagtatcc ggtgatccga gtgtggaaat taccggagcg ggtattggtg 3690 0 cggtcattcc gttaagtgct gatgttgccg gtactgctga accgtcagac tgggataatg 3696 0 ctgaaacaca tacccgtccg tcaggaaatg aaactgcttc cagctcccct tcctggtatt 3702 0 acgtggtggt tcttgctggt cagtcaaacg gtatggctta cggtgaaggt ctgccactgc 3708 0 cggagacata tgaccgcccc gaaccgcgta ttatgcagtt agcccgtcgc agtacagtca 3714 0 cgccgggagg taaagcctgt cagtataacg acatcattct ggccgaccac tgtctgcatg 3720 0 atgtgcagga tatgagtgga aaaaatcacc cgaaagcgga tgtggctaaa gggcaatatg 3726 0 gcaccgtggg tcaggggctt cacattgcca aaaaactgct gccgtttatt ccggcagatg 3732 0 cggggattct gctggttccc tgctgccgtg gtggttctgc attcacggcg ggtgctgacg 3738 0 gcacgtacag tgacagcacg ggtgcttcag aggactcagc ccgctggggt gtggataagc 3744 0 cgctgtataa ggacttaatc agccggacaa aagcggcact ggcgaagaac ccgaaaaacc 3750 0 gcctgcttgc tgtggtgtgg atgcagggcg agtttgatat tgatgcgaag ccgacggagc 3756 0 attccgcgct gtttctggcg atggtggaaa aattccgcgc agacctggct gaacaggcgg 3762 0 aacagtgtac cggtggcagt gctgctggcg ttccgtggat ttgtggcgat accacgtatt 3768 0 tctggaaaca gaaaaatgaa ccggcatacc aggcaatcta tggcggctac aaaaacaaaa 3774 0 cagataaaaa cattcatttc gttccattaa tgacagatga aaatgacgcg aatgtaccca 3780 0 ccaacaatcc ggcagaagac ccggatattg aatccattgg ttattacggc tcaacgtggc 3786 0 gtaacagtgc cgccacctgg acatctgcgg accgggccag ccatttcagt tcatgggcac 3792 0 gtcgtgggat tatttccgac cgtctggcca cggcagttct gactcatgcg gggcgaacca 3798 0 cagtaaaagc cgatgttcca tcttctgaaa ctgaagcacc agtgccgtca ccttcagaaa 3804 0 ctgaagcagt aaccacaaca ctgctgtctt atcgtgtcag tgagtcagaa ggaaatctga 3810 0 aagcccaggg ctgggagccg gctggcggta aagctgaaat tatcagtgat gcaggaggca 3816 0 caggtggtaa ggcaatgaaa ctgaccaagg aaacaggtaa atcatcctgg tatctggatc 3822 0 atgatgccgg tactggtgct gaactgctga aaaatggtgg tttaatcagt tgtcgtttta 3828 0 aagtacctgg cgacctggtg gcaaaccagt atgtcatggg gctttactgg ccggtttcct 3834 0 ctctgccgca gggtgtcacc ctgacagggg atgcagggaa taatctgctg gcatcgttct 3840 0 acatccagac agacgcaaaa gacctgaatg tgatgtacca caatgcaaaa gtggcaacaa 3846 0 ataaccagaa actgggaacc tttggtgcat ttgataatga atggcatacg ctggccttcc 3852 0 gttttgcagg aaataacagc cttcaggtta ttccggttat tgatggtcag gatggtgccg 3858 0 cgtttaccct gacgcagtca ccagtaggaa ctttcccggt ggacaaactc cgcgtaacgg 3864 0 atatcacaaa aaatgcaact tacccggtgc tgattgacag cattgtggtg gaagtgaaaa 3870 0 aagcggtaac agaataaaaa aatcccgccg gtcatgatat ggctggcggg agctacctaa 3876 0 cccataaagg aaaataaaaa tactcccgaa ggagtggtta tcagtcgctt cgatgttttt 3882 0 acccgataac gaattatgta gtcaatatca aaggtaaggt tatatgacat tcgttcatac 3888 0 aatgctgctt tatttctgcg ctgtggtcag tgcgttatat ctggtgagcg gtggttataa 3894 0 ggtcatcaga aattatattc gccgtaaaat tgatgatgcg gcagctgaaa aactcagtaa 3900 0 aacagcacag gcaccgtcat ccccaaacga cccgaccccg ctctgataac ggggcaatat 3906 0 acctgcaaaa ggagaatatt catgccagag attaaaggca cggttactga agagcttgtc 3912 0 aaacaggcac tttattctga agaagtgaac cgcgtgctga aggcgcaggt tcgcaaggat 3918 0 tttgaggcac aaatcgacgc atatgttgat gaagtgctgg cccgaatggt tggccgttct 3924 0 ccggctgaaa acagcacgga aaatgatcct caacccgtag agcaaccaga gccggttcag 3930 0 cccggaactg acggtactat gatgtaacaa taccgaccgg caggtttccc tgccgggtga 3936 0 gtttgttaat gcacgttttg tgtattttcc ctcctgggag aacaggcagg acatatcagc 3942 0 atcctgaaac aggaagcatt tttgggtttg tatgtcttgc cattttgaga tcgagaacgg 3948 0 cgatagatga gctgtaaggg agtcttacag gcagggcaaa caggctcttt catccatgat 3954 0 aaagatctcc tttttatgca tctctgcttt acaggagacc ggggaatatc ataggatacg 3960 0 ccacgagctc gaagtaaagc attgatgcaa gtttttacag attgacccag catagttcca 3966 0 gctatgctgg gtttcacttt tatgtagtat cctgttgatt tgaaacatac tacatatacg 3972 0 cgtgatccta ccttcactgt ataaaaagtc aataaaatga tcattttatg atcgttttca 3978 0 ccacctaact cttcgttttc tttaagtaaa taatcacctc cctgaatcat tgttgatgac 3984 0 ttttcaatct atttgttgta tcaattaaac aaatcgaatc gatcgttttt gtcgatcgat 3990 0 tgcatgagaa aggcatcaac aacaaagcag gaggttatgc ggtcatgtat cgaaacatac 3996 0 ggtgccgaca ctgcaataag ctactggcac gggccagttt cagttatctg gaagtaaaat 4002 0 gtccgcgctg taaaaccctc aatcaaatca catctccgag cgccacagag caccccacat 4008 0 acacaaggaa atcctgtcgt ggggaacaga aagcaagtca catcccgaat catcagcacg 4014 0 cctgaactta ttcgctataa cgacaatatc gttggttatg gctcccgtga gttgcgggtt 4020 0 gagacaataa gttgctggct ggccagactg gtcatcgtca ataaacatta cagccaccgt 4026 0 ttcgtaaata actcctacct tcatctgggc atattttcag aacgggaact tgttggcgta 4032 0 atgcaatggg gttacgccct taacccaaac agtggtgcac gcgtcgtaac gggtacgcag 4038 0 aaccgagaat atatggagct taaccggcta tggctgcatg actgtatgcc gagaaactcc 4044 0 gaatcaaggg caatcagtta cgcgctcaag ctaatcaggc agctttatcc gcaggtacag 4050 0 tgggttcagt cgtttgcaga tgagcgttgt ggctgtcttg gtgtcgtgta tcaggcaagc 4056 0 aattttgatt atgtaggcag ccatgaatca atattctatg aacttgatgg cgagtggtat 4062 0 cacgagattt gcaggaatgc cattaaacga ggcggacaac gaggtgaaca tctgagggct 4068 0 aatattgaca gagccagtgt tcataagttc cgacagtttc gttacatccg gtttctgaac 4074 0 aagagggcca gaaaacgcct caacacaaag ctattcaaag tccagcctta cccaaaacca 4080 0 caaacagtta aaactggttt gaaagagagt gaatgagcgc ttaaaaactc attctaaaac 4086 0 tcaaaagaaa agcgccgatt tagtatcaaa taagttgcgt atcggcgttt ttcagcggta 4092 0 tcaaatgaaa tgcaaatcgg tatcaaaaaa atcgccgcgc tatataaaga acaccaggtg 4098 0 tcgcctgagc gccgcaacct gatcctcttt tactgggtaa agtcgcttga tggcggggat 4104 0 catgtcgtag caaaaaccca gcccgtgaat acgttcaaag ttaaaggacg cctgttgcag 4110 0 gttggagcgc agaaacatgc tcaccagatc gccgcgtgta atttttctct gttccatgat 4116 0 ggctccgtta atcgtcaagt tggtcaaggg cggtggaagc gggggccagg agttgaggtt 4122 0 cagctttacg ccactgtgga tttagctgga tgtagaccag ggccatgatc acgccgacgc 4128 0 caccgaacgc cagcagactg agatcgaggt agccacctgc gaggaaaccg aggaaaaaga 4134 0 aaggcatcaa atatttcacg cccatcatac gtagcaccat ggcgtaaccg actaccacga 4140 0 taaaaccgcc agcaatttgc agacctcggg tcacaaattc gggaatggcg tttaacatat 4146 0 tgctcaccat atcggcgctg acgaacagcg agacaatcag tgccggaatg gcgacgcgca 4152 0 gcgcctgcac gccaagcgcg gagacatgca gaatatcgag agtgcgaaac cgtgcttctt 4158 0 ccgctgcttt atccgccgcg tgctggaaca ctacggtgat ggtacgggca aacaccgtca 4164 0 gcacctggcc tgccgcagcc acaggcaacg cgatggcgat tccggtggcg atgctttgct 4170 0 gaccaacgat aaccagaatg gcggagatta tgctggcgag tgcagaatcc ggagattgcg 4176 0 ccgcgccgac gttcatccag ccgagagcta tcaattccag cgtaccaccg agtattattc 4182 0 cggtttttaa atcaccgaga attaaaccaa tcaccgtaca ggcaattaac gggcgatgag 4188 0 tctgaaattc atccagcacg ctgcccattc cggcaataca ggaaaaaaga aatatagcaa 4194 0 tgatttgtag ggtacttatt tccatgattt gtcacctttt aagtgtcgtc atccctgcct 4200 0 gttaaagcat atgtacacag gcgctattat ttaatttgcg attaactgtt cgtttatttt 4206 0 gtagataata ttgattgagg gatctgacgc tacgacgcgt aaatccagta tgacgcctag 4212 0 attatttaac tcatgaaatg cgttaatatc atcatcatct aatgaaaccg ctttggttaa 4218 0 ctgtttttta ccgggccgcc aggccatgcc gccaatattc agggtgccta tttttacccc 4224 0 ctggcgaacc atcgctaagg catcctgtgg gcgagtgaaa agataaaaaa cggtttcgtc 4230 0 ctgatattgc gggttgtgat aaaccgcgac ggctttttca atattgacca cgttaacctt 4236 0 cattcccggt ggcgcagcct gacgcaataa tgtccggcga acttcatcgt tataaacttc 4242 0 gtcattgcag ataataatgc gctgggcgtt agccactttc gaccagacgg tagtgacctg 4248 0 accgtggatc aggcggtcat caatgcgggc gagcgtaatg ttcatcagaa atcctcctct 4254 0 gtcgttgcca gttgtttcca gacaacgcag gtttgctttg cgatttgcgt caggtgttca 4260 0 cacagttcat caacattcat gctgtcctgg ttatcaacca gttcgagcgc cagcggcaga 4266 0 gaaagtccgc tgattacccg cagacgagga ttgcgcatcg caagcatcgc tgccgcattc 4272 0 cacgggctgc cgcactgtaa atccacggca atcagccact cattttgatt gtgaatgctt 4278 0 actaattttt ccagctttgc tacgatgtct ccggcgtttt caccgggcac aaattcaacg 4284 0 gcttcaacat tggcgttgcc gtaaaccatc tgaaccgatt ccagcatggc gcaagctaat 4290 0 ttgccgtggg cacaaaaaat ggcgttgacc ataaagcctc cttagccgcg cgttttgccg 4296 0 cccgcaatgt tagtggttac tccggtgata tagctggcgc gttcagacag cagataacaa 4302 0 acaaaatcag cgatttctgc taatcttccg gcgcgcccaa taggaatggc gtttttggta 4308 0 tagccttcac gcagctgctc gacggtgata ttgcgcgtcc acgccagcgc ctcttcatat 4314 0 tccggcgtgc gtagcccggt tttttccaga atccccggcg cgataccgac cacacggata 4320 0 ccgtgtttac ccagctcttt cgaccaggag cgcgtgaagc tattgagcgc ggctttggta 4326 0 gcggcgtaac agctttggcc ttctgagcct tccagcccac tttctgagga aacattcaca 4332 0 atcacgccat catgttgttt gaccatctgt cgcgccaccg cctgcgacat cagaaaaacg 4338 0 cctttctggt tgatattgac cattttttcg aatgcagctt cgttgagttc atactgcccg 4344 0 gcaggcgctt tctcatcgac cagcagacgc gggaaattga ccccggcgtt attgaccaga 4350 0 ccgtcgatgc gaccaaaacg ctggataatt tccgctaccg tatgatttac ctctttggcg 4356 0 ctggaaatat cggtcggcca aaactgatag cctttatgac cttcatattg tccatcgcca 4362 0 ccgtgaatat ctaccatctg tacgtttgcg ccttgtgcta ataattcctc tacaatcgcc 4368 0 agaccaatac cggatgcgcc gccggtgacg ataatgattt tatcctgcaa atttaaccac 4374 0 gtttgcataa cagactcctg attttagata atagggaccc gccgtaattt ttattacgat 4380 0 aaacatcggg aagattttta tttcagtaat agttcagctg tgctgctatt cgttaccaga 4386 0 caattaatat attttccacg cagtgcacca ataattccgc tgtatttttc ttcactcatg 4392 0 gcaatgccaa tggaatatcg tgcctgcttt aatttattca tttcgataga gagtgttttt 4398 0 tcgctcatat tcgtttcaac catttcgccg tgaatatcaa aaaagcgcga gcaaatatcg 4404 0 ccagcaacct ggcgggcatt caggtcgtca ctctcttcac caccataaaa cgcatgccag 4410 0 ttagcgccgt cgcgaatggc cggtgagcca attcccacca gggcgacatc cagattatcc 4416 0 cagtaggcag agatggtttt aaagtgctga gactgcatga tcccattacg aattaatggg 4422 0 ttatccagta gagccggaaa atccgcgaga tgcgattccc ctttcagctt cgctgccgcg 4428 0 ctgtaggtta atgtgtttac gtgatagcgg ctttcgagtt taccggacgg tccgccaata 4434 0 attggtacgc agattaactg ccgcgattgc cccgcctgcg gcaagttttc aaccagtgcg 4440 0 ctcaccgcgc gaccccagga aaaaccgaca atatcgccag gctccagcaa gcgatccagc 4446 0 agttgcgcgc cgtgtaaccc catcatcgcc agttgagtct cttcatcctc atcatttccc 4452 0 gacaccacca caacgtcttt caggccaaac ttttgcttca gttgctgctc cagccagaga 4458 0 ttttcgttgt agtcatagtt gatggcgatg gtgacaattc cctgatcgcg gcctcgttta 4464 0 agcaagcggc tgatgttggt gcggtaaata cccagttcgc gcgcgatttg cgcctgcgtc 4470 0 atatcctgtt cgtaatagag ttgggcaatc ttcacaatca aacggatatc gtcactgttt 4476 0 tccattgccg cctcctggtt ctgcacattt gtgcaaatac gctttctcac cgcttgatct 4482 0 gatataaccc catcatgatg gcctttcaaa gcgatttttc actctttgca tggggagaaa 4488 0 tagcgctttc tcttgcacat ttgtttctct gcgcagtagt tatcagcaca ggtgtgcagc 4494 0 gattcgtaat atgttgatta tccttatttt gccacgcaaa tttgcattgt acttccggag 4500 0 acacttttgt gataaaaggc gtggcagatc acatttaatt tcgac 4504 5 <210> 690 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18..173) <400> 690 Met Thr Asn Thr Ala Leu Pro Asp Ala Leu Arg Leu Pro Gly Leu Pro 1 5 10 15 Asp Asn Cys Asn Ile Leu Asn Phe Arg Asp Tyr Val Gly Arg Ile Arg 20 25 30 Leu Tyr Ser Ala Ser Gly Ile Asn Asn Val Tyr Phe Ala Thr Asn Leu 35 40 45 Ser Ala Pro * 50 <210> 691 <211> 410 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(293..1522) <400> 691 Met Lys Thr Thr Ala Leu Arg Leu Tyr Gly Lys Arg Asp Leu Arg Leu 1 5 10 15 Glu Thr Phe Asp Leu Pro Glu Met Gln Glu Asp Glu Ile Leu Ala Thr 20 25 30 Val Val Thr Asp Ser Leu Cys Leu Ser Ser Trp Lys Glu Ala Asn Leu 35 40 45 Gly Glu Asn His Lys Lys Val Pro Asp Asp Val Ala Thr Asn Pro Ile 50 55 60 Ile Ile Gly His Glu Phe Cys Gly Asp Ile Leu Ala Val Gly Lys Lys 65 70 75 80 Trp Gln His Lys Phe Gln Pro Gly Gln Arg Tyr Val Ile Gln Ala Asn 85 90 95 Leu Gln Leu Pro Asp Arg Pro Asp Cys Pro Gly Tyr Ser Phe Pro Trp 100 105 110 Val Gly Gly Glu Ala Thr His Val Val Ile Pro Asn Glu Val Met Glu 115 120 125 Gln Asp Cys Leu Leu Ala Tyr Asp Gly Glu Thr Tyr Phe Glu Gly Ser 130 135 140 Leu Val Glu Pro Leu Ser Cys Val Ile Gly Ala Phe Asn Ala Asn Tyr 145 150 155 160 His Leu Gln Glu Gly Ser Tyr Asn His Thr Met Gly Ile Arg Pro Gln 165 170 175 Gly Arg Met Leu Ile Leu Gly Gly Thr Gly Pro Met Gly Leu Leu Ala 180 185 190 Ile Asp Tyr Ala Leu His Gly Pro Val Asn Pro Ser Leu Leu Val Ile 195 200 205 Thr Asp Thr Asp Asn Asp Lys Leu Ser Tyr Ala Arg Lys His Tyr Pro 210 215 220 Ser Glu Pro Gln Thr Leu Ile His Tyr Leu Asn Ala Ala Asp Ala Ala 225 230 235 240 Phe Asp Thr Leu Met Ala Leu Ser Gly Gly His Gly Phe Asp Asp Ile 245 250 255 Phe Val Phe Val Pro Asn Glu Gly Leu Val Thr Leu Ala Ser Ser Leu 260 265 270 Leu Ala Thr Asp Gly Cys Leu Asn Phe Phe Ala Gly Pro Gln Asp Lys 275 280 285 His Phe Ser Ala Pro Ile Asn Phe Tyr Asp Val His Tyr Ala Phe Thr 290 295 300 His Tyr Val Gly Thr Ser Gly Gly Asn Thr Asp Asp Met Arg Ala Ala 305 310 315 320 Val Lys Leu Ile Glu Glu Lys Lys Val Gln Ala Ala Lys Val Val Thr 325 330 335 His Ile Leu Gly Leu Asn Ala Ala Gly Glu Thr Thr Leu Glu Leu Pro 340 345 350 Ala Val Gly Gly Gly Lys Lys Leu Val Tyr Thr Gly Lys Tyr Leu Pro 355 360 365 Leu Thr Ser Leu Thr Gln Ile Gln Asp Gln Ala Leu Ala Ala Ile Leu 370 375 380 Ala Arg His Gln Gly Ile Trp Ser Gly Glu Ala Glu Gln Tyr Leu Leu 385 390 395 400 Thr His Ala Glu Ala Ile Ser His Asp * 405 <210> 692 <211> 218 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1574..2227) <400> 692 Met Ile His Leu Val Thr Phe Asn Thr Thr Pro Ala Val Cys Gly Pro 1 5 10 15 Val Ile Gly Val Thr Ala Ala Met Glu Glu Ala Arg Ala Asn Gly Ala 20 25 30 Glu Ile Asp Asp Gly Thr Ile Asn Gly Ile Lys Val Gly Leu Met Gly 35 40 45 Pro Leu Ala Gly Val Gly Asp Pro Leu Val Trp Gly Thr Leu Arg Pro 50 55 60 Ile Thr Ala Ala Leu Gly Ala Ser Leu Ala Leu Ser Gly Asn Ile Leu 65 70 75 80 Gly Pro Leu Leu Phe Phe Phe Ile Phe Asn Ala Val Arg Leu Ala Met 85 90 95 Lys Trp Tyr Gly Leu Gln Leu Gly Phe Arg Lys Gly Val Asn Ile Val 100 105 110 Ser Asp Met Gly Gly Asn Val Leu Gln Lys Leu Thr Glu Gly Ala Ser 115 120 125 Ile Leu Gly Leu Phe Val Met Gly Val Leu Val Thr Lys Trp Thr Ser 130 135 140 Ile Asn Val Pro Leu Val Val Ser Gln Thr His Ala Ala Asp Gly Ser 145 150 155 160 Thr Val Thr Met Thr Val Gln Asn Ile Leu Asp Gln Leu Cys Pro Gly 165 170 175 Leu Leu Ala Leu Gly Leu Thr Leu Leu Met Val Arg Leu Leu Asn Lys 180 185 190 Lys Ile Asn Pro Val Trp Leu Ile Phe Ala Leu Phe Gly Leu Gly Ile 195 200 205 Ile Gly Asn Ala Leu Gly Phe Leu Ser * 210 215 <210> 693 <211> 177 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2460..2990) <400> 693 Met Ser Gln Gly Lys Glu Pro Val Ile Glu Arg Ile Gly Met Leu Thr 1 5 10 15 Lys Arg Tyr Pro Ser Arg Ser Ala Ala Ala Arg Ala Trp Gly Ile Asn 20 25 30 Ile Asn Thr Leu Asn Ser Tyr Phe Lys Gly Gly Gln Thr Gln Pro Ala 35 40 45 Pro Arg Glu Ser Ile Leu Ile Arg Ile Ser Glu Ser Glu Gly Val Ser 50 55 60 Leu Glu Trp Leu Lys Glu Gly Lys Gly Glu Ser Pro Asn Asp Val Gly 65 70 75 80 Ile Cys Gly Asn Phe Gly Cys Ser Gly Asp Lys Gly Asp Gln Leu Thr 85 90 95 Gln Met Leu Ser Phe Leu Thr Lys Asp Glu Arg Glu Gln Leu Thr Asn 100 105 110 Leu Leu Ala Arg Lys Gly Val Glu Thr Val Leu Thr Leu Leu Asp Lys 115 120 125 Glu Asn Gln Asp Leu Leu Gln Leu Glu Gly Arg Lys Arg Leu Ala Ala 130 135 140 Leu Met Ile Val Asp Met Pro Asp Asp Cys Val Arg Glu Ile Leu Glu 145 150 155 160 Lys Thr Glu Thr Ser Arg Gln Ser Asn Pro Val Glu Ser Lys Ala Gly 165 170 175 * <210> 694 <211> 83 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3181..3429) <400> 694 Met Ser Arg Arg Glu Val Ser Asp His Asp Trp Pro Pro Glu Ile Ile 1 5 10 15 Lys Ala Arg Leu His Met Ala Gly Leu Ser Leu Arg Ser Leu Ser Leu 20 25 30 Lys Ala Gly Tyr Ser Arg Asp Ser Leu Lys Ser Val Leu Arg Thr Pro 35 40 45 Cys Arg Pro Tyr Gln Gln Ile Ile Ala Asp Ala Leu Gly Val Ser Pro 50 55 60 Glu Glu Ile Trp Pro Ser Arg Tyr Gln Val Lys Ser Tyr Met Arg Lys 65 70 75 80 Ala Ser * <210> 695 <211> 697 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3431..5521) <400> 695 Met Tyr Val Ile Ala Lys Glu Leu Ile Gly Ala Pro Gly Met Pro Ala 1 5 10 15 Thr Thr Lys Gly Ile Arg Gln Ala Leu Gln Arg Tyr Val Gln Gly Lys 20 25 30 Ser Cys Cys Ser Arg Arg Arg Ser Gly Ser Lys Ala Thr Glu Tyr Ser 35 40 45 Ile Asp Cys Leu Pro Glu Val Thr Gln Gln Ala Leu Arg Glu Arg Tyr 50 55 60 Ala Leu Gln Leu Met Thr Gln Lys Ala Asp Glu Ser Pro Ala Pro Val 65 70 75 80 Val Thr Lys Ala Arg Arg Ser Ser Asp Val Val Asp Ala Val Glu Ala 85 90 95 Tyr Arg Gly Ser Pro Gln Leu Met Val Glu Arg Leu Asn Ala Leu Thr 100 105 110 Glu Asn Gln Arg Gln Val Ala Asp Ala Arg Ile Ala Ile Val Ser Glu 115 120 125 Val Met Lys Val Ala Gln Gln Pro Gly Phe Ser Cys Ala Lys Ala Ile 130 135 140 Arg Phe Ile Val Asp Asn Leu Ala Arg Ser Gln Leu Asp Glu Arg Ile 145 150 155 160 Val Ala Met Val Glu Thr Ala Asn Ala Lys Lys Gly Asn Ser Arg Ala 165 170 175 Leu Ser Glu Ile Thr Leu Lys Arg Trp Ile Ala Ala Phe Asn Lys Ala 180 185 190 Gln Asn Ala Ala Glu Arg Leu Leu Leu Leu Ala Pro Gly Lys Arg Gln 195 200 205 Glu Ile Lys Ala Glu Asp Ile Asn Trp Leu Pro Glu Phe Leu Ala Gln 210 215 220 Tyr Arg Gln Ser Asn Gly Arg Pro Met Thr Glu Ala Tyr Glu Asp Phe 225 230 235 240 Val Ala Glu Trp Gln His Arg His Ala Asp Glu Pro Tyr Met Leu Asp 245 250 255 Ile Met Pro Ser Tyr Asp Thr Ile Arg Arg Ala Met Lys Lys Leu Pro 260 265 270 Glu Val Val Lys Gln Lys Gly Arg Val Thr Gly Ser Glu Tyr Arg Gln 275 280 285 Leu Glu Gly Phe Thr Arg Arg Asp Trp Ser Arg Met Pro Val Asn Tyr 290 295 300 Val Trp Ile Gly Asp Gly His Gly Met Lys Leu Lys Cys Ala His Pro 305 310 315 320 Val His Gly Arg Pro Phe Ala Pro Glu Val Thr Phe Val Ile Asp Gly 325 330 335 Gly Thr Arg Phe Val Val Gly Trp Ser Leu Asp Leu Ala Glu Asn Val 340 345 350 Phe Ala Val Ala Gly Ala Ile Gln His Gly Ile Arg His His Gly Lys 355 360 365 Pro Phe Leu Tyr Tyr Ser Asp Asn Gly Ser Gly Glu Thr Ala Asp Ile 370 375 380 Leu Asp Lys Glu Val Val Gly Ile Leu Pro Arg Leu Gly Ile Asn His 385 390 395 400 Pro Thr Gly Ile Ala Gly Asn Pro Gln Gly Arg Gly Ile Ile Glu Arg 405 410 415 Leu Asn Arg Thr Leu Pro Met Arg Ile Ala Arg Lys Tyr Arg Thr Tyr 420 425 430 Phe Gly Lys Gly Ala Asp Arg Glu Thr Leu Arg Lys Thr Asn Arg Asp 435 440 445 Leu Arg Ser Ala Phe Thr Ala Leu Gln Gln Gly Lys Arg Leu Asn Ala 450 455 460 Arg Gln Gln Ser Ala Met Arg Asp Leu Pro Ser Trp Ser Glu Leu Ile 465 470 475 480 Asp Ala Ile Arg Asp Gly Val Glu Trp Tyr Asn Asn Arg Pro His Asp 485 490 495 Glu Leu Pro Val Lys Pro Asn Gly Lys His Tyr Ser Pro Ala Glu Phe 500 505 510 Arg Lys Lys Arg Leu Ala Glu Glu Asp Thr Glu Ile Glu Trp Leu Ser 515 520 525 Asp Val Glu Leu Arg Asp Met Phe Arg Pro Met Val Glu Arg Pro Val 530 535 540 Arg Arg Cys Glu Ile Arg Trp Leu Asn Asn Ile Tyr Tyr Ala Pro Glu 545 550 555 560 Leu Arg Asp Glu His Gly Arg Lys Val Leu Ile Ser Tyr Asp Ile His 565 570 575 Asp Ala Glu Arg Ile Thr Val Arg Arg Leu Asp Gly Ser Val Ile Cys 580 585 590 Glu Ala Val Trp Asp Gly Asn Lys Arg Glu Ala Phe Pro Val Ser Ala 595 600 605 Glu Tyr Tyr Lys Gln Gln Gln Arg Leu Lys Gly Met Arg Lys Arg Ala 610 615 620 Glu Glu Lys Ile Arg Asp Ala Glu Asp Glu Val Val Asn Val Leu Glu 625 630 635 640 His Lys Pro Gln Glu Pro Trp Leu Glu Asn Ile Tyr Arg Pro Val Gly 645 650 655 Asn Thr Val Ala Val Gln Gln Pro Ala Ile Asp Asp Glu Pro Asp Glu 660 665 670 Glu Tyr Glu Arg Asn Phe Gln Arg Gly Leu Gln Leu Leu Glu Ala Lys 675 680 685 Leu Lys Glu Asn Asp Pro Leu Ala * 690 695 <210> 696 <211> 311 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5592..6524) <400> 696 Met Thr Asp Ile Asn Asp Val Ile Lys Thr Ile Asp Glu Leu Ile Asp 1 5 10 15 Gly Gly Val Leu Thr Gln Tyr Ala Ile Ala Arg Glu Ala Gly Ile Ser 20 25 30 Asp Gly Thr Leu Ser Ala Phe Arg Lys Gly Lys Tyr Lys Gly Asp Asn 35 40 45 Ala Ala Val Ala Ala Ser Leu Arg Ser Trp Tyr Glu Asn Trp Asn Lys 50 55 60 Gln Ser Ala Leu Pro Glu Pro Pro Gln Phe Val Glu Thr Gln Thr Val 65 70 75 80 Gln Glu Leu Arg Ala Leu Phe Gln Ala Val Arg Leu Met Gly Cys Ile 85 90 95 Asn Val Ile Val Gly Val Pro Gly Val Gly Lys Thr Ala Thr Ala Arg 100 105 110 Asn Tyr Cys Gln Glu Gln Pro Asn Thr Trp Met Ile Thr Leu Ser Pro 115 120 125 Ala His Ser Ser Val Thr Glu Cys Leu Leu Glu Leu Ala Asp Ala Leu 130 135 140 Gly Ile Asp Tyr Thr Arg Ala Asn Lys Gly Ala Leu Ser Arg Ala Ile 145 150 155 160 Arg Arg Arg Leu Met Gly Thr Arg Gly Leu Val Ile Val Asp Glu Ala 165 170 175 Asp His Leu Gly Ile Asp Gly Leu Glu Gln Leu Arg Ala Ile Gln Asp 180 185 190 Ala Thr Gly Ile Gly Met Val Leu Ile Gly Asn Pro Arg Gly Leu Phe 195 200 205 Lys Gly Gly Arg Arg Ala Phe Asp Asp Leu Ser Arg Leu Phe Ser Arg 210 215 220 Leu Ala Arg Thr Lys Gln Leu Arg Lys Ala Lys Lys Ala Asp Val Leu 225 230 235 240 Ala Ile Ala Arg Ala Trp Gly Ile Ser Gly Glu Ala Glu Leu Ala Val 245 250 255 Met Gln Ala Ile Ala Glu Lys Pro Gly Ala Leu Arg Val Leu Thr His 260 265 270 Thr Leu Asn Gln Ala Trp Leu Thr Ala Ser Gly Glu Gly Ala Ala Leu 275 280 285 Thr Glu Lys His Ile Asn Ala Ala Phe Lys Glu Val Tyr Thr Asn Pro 290 295 300 Glu Leu Leu Ser Gln Val * 305 310 <210> 697 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6527..6748) <400> 697 Met Ala Val Phe Tyr Ile Pro Asp Ile Tyr Gly Arg Phe Tyr Leu Val 1 5 10 15 Asn Phe Asp Asn Val Lys Val Ile Ser Leu Ala Glu Asn Lys Glu Cys 20 25 30 Gly Asp Leu Leu Phe Glu Phe Asn Asp Arg Thr Arg Met Val Ile Ser 35 40 45 Ala Gly Leu Asp Arg Glu Gly Ala Thr Asp Val Tyr Ser Gly Ile Cys 50 55 60 Arg Ser Val Gly Ala Lys Gln Val Ser * 65 70 <210> 698 <211> 85 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6761..7015) <400> 698 Met Asn Met Gln Ser Cys Gly Asn Lys Met Asn Leu Phe Asp Ser Leu 1 5 10 15 Asn Ser Ala Arg Arg Leu Thr Glu Leu Ala Gly Ala Val Leu Glu Arg 20 25 30 Ser Lys Arg Tyr Pro Gln Arg Phe Ala Leu Lys Thr Thr Pro Pro Val 35 40 45 Gly Asn Val Gln Gly Thr Gly Glu Ile Glu Ile Thr Ile Gln Thr Asn 50 55 60 Gly Leu Arg Arg Arg Val Lys Ala Thr Arg Ile Ser Gly Cys Thr Val 65 70 75 80 Tyr Trp Glu Val * <210> 699 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7017..7298) <400> 699 Val Lys Lys Asn Leu Ile Ala Trp Ala Trp Ser Ser Gly Leu Ile Glu 1 5 10 15 Phe Gly Tyr Val Leu Pro Glu Gly Ala Leu Pro Ile Val Ala Gly Lys 20 25 30 Pro Ala Thr Val Arg His Val Ile Glu Val Met Ala Arg His Gly Arg 35 40 45 Asp Glu Gln Glu Gln Leu Leu Val Pro Gly Ile Pro Glu Ala Val Thr 50 55 60 Glu Glu Glu Ala Phe Asn Ala Met Ile Arg Phe Cys Arg Glu Val Arg 65 70 75 80 Arg Arg Val Ser Tyr Pro Asn Arg Thr Arg Thr Arg Gly * 85 90 <210> 700 <211> 91 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7295..7567) <400> 700 Val Ser Lys Val Val Arg Ile Ile Phe Glu Tyr Lys Glu His Val Ile 1 5 10 15 His Lys Asn Ala Asp Gly Thr Val Arg Met Gly Val Ser Leu Asp Ile 20 25 30 Arg Ser Thr Gly Ile Lys Gln Lys Gly Asp Gly Pro Ala Met Ile Phe 35 40 45 Gly Val Val Met Leu Ala Glu Ser Arg Asp Phe Ala Glu Leu Val Ala 50 55 60 Met Lys Ala Ser Ala Leu Met Lys Asp Met Ser Met Arg Ser Gly Val 65 70 75 80 Ile Lys Gly Asn Glu Phe Asn Gln Gln Gly * 85 90 <210> 701 <211> 98 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7572..7865) <400> 701 Met Ser Lys Val Arg Val Ile Phe Glu Phe Lys His Val Ser His Asp 1 5 10 15 Glu Lys Pro Ala Gly Asn Asp Cys Val Glu Val His Glu Lys Ile Gly 20 25 30 Val Asp Val Lys Thr Glu Arg Asp Thr Asn Asn Arg Pro Thr Ser Leu 35 40 45 Cys Asp Val Tyr Ala Ser Ile Leu Gln Tyr His Ser Pro Glu Ile Ile 50 55 60 Gln Phe Leu Ser Ala Glu Phe Gln Ala Ser Val Gln Ala Phe Gly Ala 65 70 75 80 Asp Ala Ile Ile Lys Arg His Arg Val His Lys Ala Ser Gly Thr Leu 85 90 95 Gln * <210> 702 <211> 177 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7877..8407) <400> 702 Met Ala Lys Arg Val Thr Lys Leu Lys Ala Ala Ala Glu Ala Ala Pro 1 5 10 15 Gln Thr Arg Glu Glu Val Ser Arg Asp Ile Arg Thr Leu Gly Asp Ile 20 25 30 Gln Arg Glu Ala Leu Arg Leu Glu Thr Ala Met Asn Asp Glu Val Ala 35 40 45 Glu Ile Thr Ala Arg Tyr Thr Pro Gln Ile Glu Asn Leu Lys Lys Glu 50 55 60 Ile Lys Val Leu Phe Lys Gly Ile Gln Asp Trp Cys Lys Thr Asn Arg 65 70 75 80 Asp Glu Leu Thr Asn Gly Gly Lys Thr Lys Thr Ala Asn Leu Thr Thr 85 90 95 Gly Thr Val Ser Trp Arg Leu Gly Asn Pro Ser Cys Ser Val Ser Arg 100 105 110 Asp Val Glu Gly Val Ile Glu Met Leu Arg Arg Met Gly Leu Glu Arg 115 120 125 Phe Ile Arg Thr Lys Glu Glu Val Asn Lys Glu Ala Val Leu Ala Glu 130 135 140 Pro Asp Ala Val Lys Gly Ile Ala Gly Ile Lys Val Asn Lys Gly Ala 145 150 155 160 Glu Ser Phe Tyr Val Glu Pro Phe Glu Gln Asp Ala Gly Leu Asn Lys 165 170 175 * <210> 703 <211> 181 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8505..9047) <400> 703 Met Ala Tyr Phe Tyr Phe Lys Leu Asp Arg Val Gln Thr Asn Lys Tyr 1 5 10 15 Phe Thr Lys Tyr Gln Gln Thr Val Leu Pro Leu Arg Asn Ser Ile Leu 20 25 30 Arg Ala Leu Leu Lys Asn Thr Gly Ala Ala Gly Leu Arg Leu Lys Pro 35 40 45 Phe Ala Met Asp Val Ile Ser Glu Phe Tyr Phe Ser Gly Ala Leu Pro 50 55 60 Ala Gly Trp Arg Lys Arg Asp Asp Val Ala Phe Ile Gly Asp Gly Pro 65 70 75 80 Cys Phe Ile Ala Arg Pro Asp Glu Ser Cys Pro Glu Gly Pro Ala Ile 85 90 95 Ala Ala Met Ile Glu Thr Ala Glu Arg Glu Leu Arg Lys Arg Pro Asp 100 105 110 Phe Leu Val Trp Leu Cys Glu Lys Leu Gly Val Met Arg Ile Pro Ser 115 120 125 Met Phe Asn Thr Asp Ser Trp Trp Thr Pro Ser Leu Ser Arg Asp Ala 130 135 140 Leu Cys Val Val Phe Lys Val Gly Ala Tyr Gly Arg Glu Ile Lys Gly 145 150 155 160 Cys Ile Pro Glu Glu Cys Gln Glu Ile Lys His Ser Glu Tyr Val Ala 165 170 175 Leu Thr Glu Glu * 180 <210> 704 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9051..9584) <400> 704 Met Ile Asp Ala Lys Val Leu Glu Gly Val Lys Asn Trp Leu Ser Ile 1 5 10 15 Tyr Gly Arg Leu Thr Cys Gly Ile Leu Ala Glu Lys Met Asn Met Pro 20 25 30 Pro Ser Ser Met Val Tyr Phe Leu Arg Asp Ala Val Asp Ala Gly Val 35 40 45 Leu Thr Glu Cys Asn Gly Phe Tyr Asp Ile Pro Arg Pro Arg Pro Val 50 55 60 Gln Pro Val Arg Arg Lys Cys Ser Gln Glu Gly Ala Ala Asp Asp Val 65 70 75 80 Gln Trp Cys Ser Phe Arg Lys Ser Leu Pro Trp Ile Glu Gly His Asp 85 90 95 Ile Pro Ser Met Ala Trp Glu Phe Ala Gln Gly Val Leu Thr Cys Glu 100 105 110 Thr Val Tyr Val Val Ala Glu Val Asp Glu Gln Ala Met Lys Glu Gly 115 120 125 Val Pro Gln Phe Val Met Ala Tyr Ile Asp Ile Arg Leu Gly Val Ile 130 135 140 Ile Cys Gly Leu Ser Gly Trp Asn Ile Thr Glu His Val Leu Arg Tyr 145 150 155 160 Leu Ile Val Asp Arg Thr Ala Ala Pro Ala Gly Ile Ser Ala Glu Val 165 170 175 Ala * <210> 705 <211> 172 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9584..10099) <400> 705 Met Phe Phe Lys Thr Ser Asn Pro Ser Ala Leu Ala Ala Trp Gln Lys 1 5 10 15 Tyr Gln Gln Asp Cys Gln Lys Val Lys Asp Glu Ala Lys Arg Leu Glu 20 25 30 Ala Val Leu Asn Val Ala Cys Arg Ser Val Phe Val Ser Gly Ile Ser 35 40 45 Gly Phe Cys Phe Lys Gly Leu Arg Phe Met Asp Asp Lys Tyr Pro Phe 50 55 60 His Arg Asp Leu Trp Arg Lys Pro Thr Ala Ser Asn Gly Trp Ser Cys 65 70 75 80 Thr Pro Arg Thr Ser Arg Ile Pro Lys Ala Leu Arg Val Ala Ser Asp 85 90 95 Glu Leu Asn Ser Leu Trp Arg Glu Tyr Ser Pro Val Thr Tyr Ala Arg 100 105 110 Thr Asp Ala Leu Leu Phe Trp Leu Gly Ile Asp Phe Ser Ala Ile Leu 115 120 125 His Gly Pro Val Lys Trp Phe Cys Val Asp Asp Val Ile Tyr Leu Gln 130 135 140 Cys Glu Asp Asp Ser Ala Lys Arg Lys Met Thr Glu Ile Leu Ser Asp 145 150 155 160 Glu Phe Tyr Ala Ala Glu Lys Arg Val Gly Gly * 165 170 <210> 706 <211> 97 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10364..10654) <400> 706 Met Thr Gly Lys Gln Ile Gly Glu Tyr Leu Gly Arg Asp Arg Asp Ser 1 5 10 15 Val His Asn Arg Ala Arg Tyr Ile Gly Val Ser Met Lys Lys Tyr Gly 20 25 30 Glu Leu Leu Pro Phe Thr Arg Ile Pro Asp Asp Asp Val His Leu Ile 35 40 45 Arg Glu Leu Arg Asp Ala Glu Ser Pro Arg Arg Leu Thr Phe Arg Glu 50 55 60 Ile Gly Glu Lys Phe Glu Leu Ser Glu Gly Thr Val Ser Phe Ile Tyr 65 70 75 80 His Arg Arg Arg Thr Ala Glu Asp Val Val Leu Arg Glu Leu Thr Thr 85 90 95 * <210> 707 <211> 125 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10833..11207) <400> 707 Met Arg Lys Ile Thr Thr Leu Ser Glu Leu Gln Glu Met Asn Met Ser 1 5 10 15 Ile Glu Leu Arg Ser Ser Tyr Glu Tyr Arg Lys Ile Leu Ile Ala Gly 20 25 30 Gly Met Lys Pro Glu Asp Ala Glu Lys Ile Val Ser Phe Met Asp Lys 35 40 45 Glu Cys Asp Lys Arg Asp Met Pro Glu Ile Ile Met Asp Asp Met Ile 50 55 60 Leu Asp Ser Ala Val Ala Leu Ser Pro Leu Trp Ile Val His Ser Leu 65 70 75 80 Ala Glu Ile Ala Lys Gly Thr Asp Lys Gln Ala Ala Val Ala Ala Leu 85 90 95 Gln Thr Leu Asn Glu Met Arg Ile Ser Pro Arg Pro Thr Leu Ile His 100 105 110 Met Ile Leu Ser Ser Met Glu Asp Lys Ala Asn Glu * 115 120 <210> 708 <211> 66 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11200..11397) <400> 708 Met Asn Ser Leu Pro Ala Gly Trp Ala Arg Pro Leu Met Ala Arg Lys 1 5 10 15 His His Phe Phe Lys Thr Gly Glu Asn Ile Ser Ile Cys Gly Arg Trp 20 25 30 Leu Tyr Leu Ala His Asn Arg Glu Pro Asp Thr Phe Glu Ser Pro Asp 35 40 45 Asp Cys Ala Glu Cys Arg Arg Arg Val Asn Lys Glu Lys Asp Asn Gly 50 55 60 Gln * 65 <210> 709 <211> 99 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11387..11683) <400> 709 Met Asp Asn Ser Ser Leu Leu Phe Trp Cys Leu Tyr Ile Thr Ser Phe 1 5 10 15 Phe Gly Ala Phe Val Ile Thr Arg Trp Leu Cys Arg Lys Ile Ile Cys 20 25 30 Phe Phe Asp Lys Arg His Pro Val Glu Arg Ala Ala Asp Ala Leu Ile 35 40 45 Gln Gln Ala Ile Val Leu Tyr Ser Gly Glu Phe Phe Cys Arg Ile Thr 50 55 60 Thr Arg Asp Gly Trp His Ile Met Ile Ile Pro Pro Thr His His Ala 65 70 75 80 Arg Trp Asp Glu Ala Glu Lys Ala Phe His Val Arg Lys Lys Val Asn 85 90 95 Thr Val * <210> 710 <211> 170 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11680..12189) <400> 710 Met Arg Gly Lys Leu Ile Ser Ala Ile His Val Ala Lys Arg Glu Leu 1 5 10 15 Ala Leu Asp Asp Glu Thr Tyr Thr Ser Ala Leu Leu Ala Ala Thr Gly 20 25 30 Lys Thr Ser Cys Arg Asp Met Ser Pro Asp Glu Leu Ser Arg Val Leu 35 40 45 Asp Val Phe Lys Lys Arg Gly Phe Lys Val Arg Gln Asn Pro Val Asn 50 55 60 Arg Ala Leu Lys Pro Gly Thr Val Thr Ala Lys Ile Arg Ala Ile Trp 65 70 75 80 Lys Val Met His Arg Gln Gly Phe Ile Thr Asp Gly Ala Glu Thr Ala 85 90 95 Leu Asn Arg Trp Val Lys Ser Gln Thr Ala Ala Gln Asn Gly Gly Glu 100 105 110 Gly Val Ala Asn Trp Gln Trp Leu Glu Gln His Pro Ala Leu Ala Ser 115 120 125 Asp Val Leu Glu Arg Leu Lys Arg Trp His Arg Arg Lys Met Leu Ala 130 135 140 Ala Met Gly Met Pro Glu Arg Thr Leu Met Gly Tyr Asp Ala Val Cys 145 150 155 160 Arg Gln Tyr Glu Lys Ser Leu Pro Arg * 165 <210> 711 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12259..12684) <400> 711 Met Ala Glu Thr Gln Met Ser Met Phe Gly Gly Asp Ser Glu Gln Leu 1 5 10 15 His Ala Leu Ile Asp Arg Leu Asp Asp Ile Pro Asp Asp Val Leu Lys 20 25 30 Lys Asn Trp Pro Arg Thr Leu Ser Glu Leu Val Glu Val Thr Gly Ala 35 40 45 Glu Leu Gln Arg Gln Gly Ile Glu Pro Val Leu Ala Gly Lys Leu Ala 50 55 60 Arg Lys Val Ala Ala Ala Gln Ala Ala Tyr Met Gly Gly Arg Gly Tyr 65 70 75 80 Tyr Leu Pro Val Gly Glu Ser Leu Phe Ala Glu Leu Arg Asn Asn Glu 85 90 95 Ile Phe Ser Arg Trp Asp Arg Gly Glu Lys Ile Glu Ser Leu Arg Arg 100 105 110 His Tyr Arg Met Ser Glu Thr Gln Ile Tyr Thr Val Ile Arg Glu Gln 115 120 125 Arg Arg Leu His Leu Ala Arg Thr Gln Pro Pro Leu Phe * 130 135 140 <210> 712 <211> 167 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12756..13256) <400> 712 Met Pro Lys Leu Pro Ala Pro Leu Arg Lys Lys Leu Ile Ala Leu Val 1 5 10 15 Leu Ala Gly Ala Gly Thr Phe Thr Ile Ala Thr His Tyr Thr Gly Tyr 20 25 30 Trp Glu Gly Lys Glu Asn Ser Thr Tyr Ile Asp Pro Thr Gly Thr Pro 35 40 45 Thr Ile Cys Tyr Gly His Thr Gly Pro Asp Val Lys Pro Gly Met Thr 50 55 60 Leu Thr Asp Glu Glu Cys Leu Glu Leu Leu Glu Lys Asp Met Lys Trp 65 70 75 80 Ala Phe Ala Ala Ile Asp Arg Arg Val Gln Val Pro Leu Thr Arg Gly 85 90 95 Gln Thr Val Ala Leu Ala Ser Trp Ile Phe Trp Ala Gly Glu Thr Asn 100 105 110 Phe Arg Asn Ser Thr Leu Leu Arg Leu Ile Asn Ala Gly Gln Met Pro 115 120 125 Ala Ser Cys Lys Gln Tyr Ile Arg Trp Ile Tyr Ser Lys Gly Val Lys 130 135 140 Leu Pro Gly Leu Glu Ala Arg Arg Ser Ala Asp Glu Trp Leu Cys Arg 145 150 155 160 Tyr Asp Leu Pro Lys Val * 165 <210> 713 <211> 86 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13462..13719) <400> 713 Val Arg Glu Arg Asp Glu Ala Arg Gln Val Leu Ala Asn Gln Gln His 1 5 10 15 Thr Leu Gln Leu Ile Ser Gln Ile Ser Glu Ala Ala Thr Asn Glu Lys 20 25 30 Gln Gln Asn Ile Gln His Ser Glu Gly Gln Gln Ser Val Val Arg Arg 35 40 45 Ser Leu Ala Ala Val Pro Ala Ala Ser Ala Pro Val Pro Asp Asp Val 50 55 60 Ala Asp Arg Val Arg Arg Ala Val Cys Glu Ile Arg Ala Cys Glu Ala 65 70 75 80 Gly Ala Asp Pro Arg * 85 <210> 714 <211> 149 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13475..13921) <400> 714 Met Arg Arg Val Arg Cys Trp Gln Ile Ser Ser Thr Pro Cys Asn Ser 1 5 10 15 Phe His Lys Ser Val Arg Arg Pro Arg Met Lys Asn Asn Arg Thr Phe 20 25 30 Ser Thr Ala Arg Gly Ser Arg Ala Leu Ser Ala Gly Arg Trp Gln Gln 35 40 45 Cys Leu Arg Pro Leu Pro Leu Phe Leu Met Met Trp Leu Ile Gly Cys 50 55 60 Ala Gly Pro Ser Val Lys Tyr Val Pro Val Lys Pro Val Pro Ile Pro 65 70 75 80 Ala Glu Trp Leu Ala Asp Cys Leu Val Pro Pro Ala Pro Glu Pro Phe 85 90 95 Thr Phe Gly Ala Ser Val Thr Tyr Asn Leu Gln Leu Leu Ala Val Ile 100 105 110 Lys Asn Cys Asn Val Asp Lys Ala Ser Ile Arg Arg Leu Glu Thr Arg 115 120 125 Arg Gln His Glu Phe Thr Asp Met Ala Gly Thr Pro Ala Val Pro Ala 130 135 140 Gly Lys Thr Lys * 145 <210> 715 <211> 76 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13931..14158) <400> 715 Met Asp Asp Ser Asp Arg Ala Gln Ala Val Met Glu Arg Gly Ser Glu 1 5 10 15 Arg Ala Leu Cys Asn Arg Leu Thr Arg Lys Arg Gln Ala Val Asp Thr 20 25 30 Pro Gly Arg Arg Val Cys Ala Asp Cys Gly Gly Glu Ile Pro Ala Ala 35 40 45 Arg Leu Val Ala Val Pro Asp Ala Ile Arg Cys Val Asn Cys Gln Asn 50 55 60 Ile Met Glu Ala Arg His Val Gly Gln His Arg * 65 70 75 <210> 716 <211> 103 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14139..14447) <400> 716 Met Trp Val Ser Ile Val Lys Asp Tyr Val Val Pro Ile Leu Ser Ala 1 5 10 15 Thr Ala Thr Ala Gly Gly Ile Phe Met Ala Leu Met Arg Lys Thr Phe 20 25 30 Val Pro Arg Glu Ala Phe Glu Lys Leu Ser Asp Arg Val Glu Lys Val 35 40 45 Glu Thr Arg Leu Ser Ser Leu Pro Thr Glu Ala Glu Val Asn Arg Leu 50 55 60 Asn Val Glu Ile Val Thr Leu Arg Gly Glu Leu Lys Thr Thr Asn Ala 65 70 75 80 Thr Leu Arg Ser Val Ser Tyr Gln Asn Glu Leu Leu Leu Glu Gln Ala 85 90 95 Val Arg Lys Lys Thr Gln * 100 <210> 717 <211> 97 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14444..14734) <400> 717 Met Ser Asp Phe Ile Thr Glu Asp Gln Arg Leu Val Ile Leu Arg Ser 1 5 10 15 Leu Ala Asp Tyr Asn Gly Glu Leu Gly Glu Ser Val Leu Gln Asp Cys 20 25 30 Leu Asp Asp Tyr Gly His Arg Val Ser Arg Asp Thr Val His Thr His 35 40 45 Ile Ala Trp Leu Ala Glu Gln Gly Leu Val Arg Lys Arg Val Leu Ile 50 55 60 Asn Gly Tyr Phe Ile Ala Glu Leu Thr Gly Arg Gly Gln Asp Val Ala 65 70 75 80 Glu Gly Arg Val Cys Val Pro Gly Val Lys Lys Pro Arg Ala Arg Gly 85 90 95 * <210> 718 <211> 194 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14737..15318) <400> 718 Met Asp Lys Pro Thr Arg Gly Arg Val Arg Lys Val Asp Leu Leu Pro 1 5 10 15 Asp Ser Ile Arg Lys Pro Leu Leu Glu Met Leu Arg Glu Lys Arg Leu 20 25 30 Thr Gln Val Gln Ile Arg Glu Glu Ile Asn Arg Leu Ile Arg Glu Ala 35 40 45 Gly Leu Pro Glu Glu Gln Gln Leu Ser Pro Ala Ala Ile Ser Arg Glu 50 55 60 Ala Ser Arg Asn Glu Leu Ile Ala Arg Asn Leu Arg Asp Leu Arg Glu 65 70 75 80 Gln Thr Lys Ala Met Met Ala Glu Leu Gly Asp Lys Pro Thr Gly Glu 85 90 95 Thr Thr Ala Leu Ile Leu Glu Met Ser Arg Ala Leu Met Tyr Arg Arg 100 105 110 Leu Arg Ala Ala Thr Glu Ser Leu Asn Ser Asp Ser Asp Val Asp Met 115 120 125 Arg Leu Ile Lys Asp Ile Leu Leu Ser Ala Gln Arg Ala Glu Ser Ala 130 135 140 Ala Glu Arg Ser Ile Lys Arg Glu Lys Glu Ile Arg Ala Ala Phe Ala 145 150 155 160 Glu Glu Met Ala Asn Ala Val Thr Asp Glu Leu Arg Gly Val Asp Gly 165 170 175 Met Ser Glu Gln Leu Glu Ser Arg Ile Lys Gly Ile Leu Leu Gly Lys 180 185 190 Ala * <210> 719 <211> 555 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15318..16982) <400> 719 Met Asn Asn Ala Glu Glu Leu Ser Pro Leu Leu Thr Asn Thr Val Ser 1 5 10 15 Thr Arg Lys Ile Asp Leu Ala Gly Glu Lys Ala Leu Leu Gly Val Asp 20 25 30 Val Pro Asp Ser Leu Asp Leu Pro Gly Asp Met Pro Val Phe Leu Asp 35 40 45 Tyr Gln Ala Arg Trp Phe Glu Asp Glu Ser Glu Val Cys Ile Ala Glu 50 55 60 Lys Ser Arg Arg Thr Gly Leu Thr Trp Ala Glu Ala Gly Arg Asn Val 65 70 75 80 Ile Thr Ala Ala Lys Pro Lys Arg Arg Gly Gly Arg Asn Val Phe Tyr 85 90 95 Val Gly Ser Lys Gln Glu Met Ala Leu Glu Tyr Ile Ser Ala Cys Ala 100 105 110 Leu Phe Ser Arg Ala Phe Asn Gln Leu Ala Asp Ala Asp Val Tyr Glu 115 120 125 Gln Thr Phe Trp Asp Arg Asp Lys Lys Glu Glu Ile Leu Thr Tyr Met 130 135 140 Ile Arg Phe Pro Asn Ser Gly Phe Lys Ile Gln Ala Leu Ser Ser Arg 145 150 155 160 Pro Ser Asn Leu Arg Gly Leu Gln Gly Asp Val Val Ile Asp Glu Ala 165 170 175 Ala Phe His Glu Ser Leu Asp Glu Leu Leu Lys Ala Ala Met Ala Leu 180 185 190 Thr Met Trp Gly Ala Arg Val Arg Ile Ile Ser Thr His Asn Gly Val 195 200 205 Asp Asn Leu Phe Asn Gln Tyr Ile Gln Glu Ala Arg Glu Gly Arg Lys 210 215 220 Asp Tyr Ser Val His Arg Ile Thr Leu Asp Asp Ala Ile Ala Asp Gly 225 230 235 240 Leu Tyr Arg Arg Ile Cys Tyr Val Thr Gly Arg Glu Trp Ser Pro Glu 245 250 255 Ser Glu Gln Lys Trp Arg Asp Asp Leu Tyr Lys Asn Ala Pro Thr Arg 260 265 270 Glu Asp Ala Asp Glu Glu Tyr Gly Cys Ile Pro Lys Lys Ser Gly Gly 275 280 285 Ala Tyr Ile Pro His Ala Leu Ile Glu Met Ala Met Leu Arg Asp Ile 290 295 300 Pro Ile Leu Thr Phe Glu Ala Pro Asp Asp Phe Ile Ser Arg Ala Ala 305 310 315 320 Trp Leu Arg Glu Ser Glu Val Leu Thr Trp Cys Glu Glu His Leu Lys 325 330 335 Pro Leu Leu Glu Ala Leu Asn Pro Arg Ser Arg Phe Ser Phe Gly Glu 340 345 350 Asp Phe Ala Arg Thr Gly Asp Leu Ser Cys Phe Val Leu Leu Glu Ile 355 360 365 Thr Glu Ser Leu Ala Lys Arg Glu Val Phe Arg Val Glu Leu Arg Asn 370 375 380 Leu Pro Tyr Ala Gln Gln Glu Gln Val Met Met Tyr Ile Leu Thr Arg 385 390 395 400 Val Pro Ala Leu Val Gly Ala Ala Phe Asp Ala Thr Gly Asn Gly Gly 405 410 415 Tyr Leu Ala Glu Ala Ala Leu Leu Ala Phe Gly Pro Asp Ile Ile Asp 420 425 430 Cys Val Met Leu Ser Pro Lys Trp Tyr Gly Glu Trp Met Pro Lys Leu 435 440 445 Lys Ala Glu Phe Glu Asp Gln Asn Ile Leu Val Ala Arg His Gln Thr 450 455 460 Thr Leu Asp Asp Leu Arg His Val Lys Val Val Asn Gly Ile Pro Gln 465 470 475 480 Ile Asp Lys Gly Arg Thr Lys Asp Gln Asn Ala Thr Ala Val Asn Ala 485 490 495 Arg Arg His Gly Asp Phe Ala Val Ala Leu Cys Met Ala Asn Arg Ala 500 505 510 Ser Tyr Met Glu Gly Phe Ile Leu Asp Glu Ser Ala Cys Gln Ala Leu 515 520 525 Pro Glu Arg Ser Arg Ala Met Glu Gly Gly Tyr Arg Asp Asp Asp Glu 530 535 540 Ala Tyr His Glu Phe Asp Arg Gly Cys Trp * 545 550 <210> 720 <211> 509 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17045..18571) <400> 720 Val Leu Asp Ile Pro Gln Ile Ala Ser Arg Tyr Ile Glu His Pro Ala 1 5 10 15 Ser Gly Ile Thr Pro Asn Arg Ala Ala Gln Cys Leu Arg Gly Ala Glu 20 25 30 Arg Gly Asp Leu Ile Ala Gln Ser Asp Leu Ala Ala Asp Ile Glu Glu 35 40 45 Lys Asp Thr His Leu Phe Ala Glu Leu Gly Lys Arg Arg Leu Ala Ile 50 55 60 Gln Ser Val Pro Trp Ser Ile Glu Pro Pro Pro Asn Ala Ser Ala Asn 65 70 75 80 Glu Lys Lys Asp Ala Glu Met Leu Asp Glu Tyr Leu His Ser Ala Asp 85 90 95 Trp Phe Asp Ala Met Leu Phe Asp Ala Thr Asp Ala Ile Leu Lys Gly 100 105 110 Tyr Ser Cys Met Glu Ile Glu His Gly Met Leu Gly Lys Met His Ile 115 120 125 Ile Arg Ala Ile Arg Trp Arg Asp Ser Gly His Phe Cys Leu Asn Pro 130 135 140 Asp Asp Leu Ser Glu Leu Arg Leu Arg Asp Gly Ser His Ala Gly Val 145 150 155 160 Ala Phe Gln Pro Phe Gly Trp Val Val His Gln Ser Arg Ser Arg Thr 165 170 175 Gly Tyr Gly Gly Ala Thr Gly Leu Val Arg Thr Leu Ile Trp Pro Phe 180 185 190 Ile Phe Lys Asn Tyr Ser Val Arg Asp Leu Ala Glu Phe Leu Glu Val 195 200 205 Tyr Gly Leu Pro Met Lys Val Gly Lys Tyr Pro Ser Gly Ala Thr Ser 210 215 220 Glu Gln Lys Ser Ala Leu Met Arg Ala Val Met Asp Ile Gly Arg Arg 225 230 235 240 Thr Gly Gly Ile Ile Pro Ala Gly Met Ser Leu Glu Phe Gln Val Ala 245 250 255 Ala Asn Gly Gln Ala Asp Pro Phe Glu Thr Met Ile Ser Trp Gly Glu 260 265 270 Arg Ser Ile Ser Lys Ala Ile Leu Gly Gly Thr Leu Thr Thr Glu Ala 275 280 285 Gly Asp Lys Gly Ala Arg Ser Leu Gly Glu Val His Asn Glu Val Arg 290 295 300 Arg Glu Ile Arg Asp Ser Asp Leu Arg Gln Leu Ala Ala Thr Leu Asn 305 310 315 320 Arg Asp Leu Val Tyr Pro Leu Tyr Ala Leu Asn Thr Ala His Ala Ile 325 330 335 Asp Ile Arg Arg Leu Pro Arg Ile Cys Phe Gln Thr Lys Glu Pro Gly 340 345 350 Asp Ile Thr Lys Ile Thr Ser Ala Val Met Gln Leu Ser Thr Gly Met 355 360 365 Asp Ile Pro Asp Pro Trp Val Arg Asp Gln Thr Gly Ile Pro Gln Pro 370 375 380 Ala Pro Gly Glu Ala Ile Phe Arg Val Arg Gln Ser Gly Asn Glu Pro 385 390 395 400 Ala Gln Thr Asp Lys Glu Met Pro Pro Glu Lys Gln Glu Lys Thr Glu 405 410 415 Gln Thr Ala Leu Ser Ala Arg Leu Pro Glu Ala Lys Ser Ser Pro Arg 420 425 430 Asp Glu Leu Asp Asp Met Gly Asp Ala Val Pro Ala Arg Arg Leu Gln 435 440 445 Asp Ala Ile Asp Pro Leu Leu Glu Pro Val Ile Asp Ala Ile Arg Thr 450 455 460 Arg Gly Leu Ala Asp Ala Leu Ala Asp Leu Pro Ala Leu Tyr Arg Glu 465 470 475 480 Met Asp Asp Ser Arg Leu Met Thr Leu Leu Ser Asp Ala Met Phe Ala 485 490 495 Ala Glu Met Lys Gly Met Leu Asp Gly Thr Gly Asp * 500 505 <210> 721 <211> 442 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18555..19880) <400> 721 Met Ala Gln Gly Ile Asp Leu Gly Tyr Ala Ala Thr Leu Pro Ser Lys 1 5 10 15 Glu Ala Val Ala Tyr Phe Arg Ala Lys Gly Ala His Ile Ser Trp Asn 20 25 30 Trp Phe Glu Thr Asp Ala Asp Val His Ala Arg Ser Phe Thr Ala Ala 35 40 45 Lys Ala Ala Arg Leu Asp Val Leu Thr Thr Leu Gln Ala Glu Val Gln 50 55 60 Arg Ala Ile Asp Glu Gly Ile Ser Gln Lys Ala Phe Ile Arg Thr Leu 65 70 75 80 Thr Pro Arg Leu Gln Lys Leu Gly Trp Trp Gly Lys Gln Ile Val Val 85 90 95 Asp Ser Ala Gly Asn Ala Glu Glu Val Gln Leu Gly Ser Pro Arg Arg 100 105 110 Leu Ala Leu Ile Tyr Asn Val Asn Thr Arg Val Ala Tyr Asn Ala Gly 115 120 125 Arg Tyr Thr Gln Met Met Asn Asn Thr Asp Thr His Pro Phe Trp Gln 130 135 140 Tyr Val Ala Val Met Asp Ser Arg Thr Arg Pro Ser His Ser Thr Leu 145 150 155 160 Asn Gly Leu Val Phe Arg Tyr Asp Asp Pro Phe Trp Lys Thr His Tyr 165 170 175 Pro Pro Asn Gly Trp Asn Cys Arg Cys Arg Val Arg Pro Leu Ser Gln 180 185 190 Ala Arg Leu Asp Ala Met Gly Leu Ser Val Ser Ser Gly Glu Asp His 195 200 205 Leu Ser Thr Arg Asn Val Glu Ala Gly Val Asp Lys Gln Thr Gly Glu 210 215 220 Val Arg Glu Met Pro Val Thr Thr Tyr Ser Asp Gly Thr Arg Thr Met 225 230 235 240 Thr Pro Asp Val Gly Trp Ser Tyr Asn Pro Gly Ser Ala Ala Phe Gly 245 250 255 Thr Asp Gln Ala Leu Ile Arg Lys Leu Ile Glu Val Lys Ser Pro Ala 260 265 270 Leu Arg Glu Met Val Val Gln Glu Met Asn Asn Ser Pro Glu Arg Gln 275 280 285 Leu Ala Phe Arg Ile Trp Ala Lys Asn Ile Met Lys Thr Arg Arg Gly 290 295 300 Gly His Asp Ile Arg Thr Leu Gly Phe Met Thr Glu Ser Ile Ala Gln 305 310 315 320 Ala Val Glu Ser Arg Thr Gly Thr Pro Pro Ala Arg Leu Leu Ala Met 325 330 335 Ser Gly Lys Asn Val Leu His Ala Asp Ser Val Lys His Gln Asn Asp 340 345 350 Gly Ile Ala Leu Thr Pro Glu Asp Phe Ala Gln Leu Pro Ala Met Leu 355 360 365 Ala Ala Pro Asp Ala Val Leu Trp Asp His Val His Gln Asn Leu Leu 370 375 380 Tyr Ile Thr Glu Thr Arg Asp Gly Thr Ala Lys Ile Ala Val Asn Ala 385 390 395 400 Pro Tyr Gly Val Lys Arg Gln Pro Asp Lys Leu Asp Val Val Ile Asn 405 410 415 Ala Tyr Arg Val Asn Lys Phe Asp Ile Glu Lys Ala Ile Glu Gly Gly 420 425 430 Lys Leu Glu Leu Leu Glu Gly Lys Leu * 435 440 <210> 722 <211> 158 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19999..20472) <400> 722 Met Ser Ser Ile Asp Ala Ala Val Val Val Asp Val Ala Arg Leu Gln 1 5 10 15 Arg Val Phe Ala Arg Leu Gln Phe Val Gly Gly Gly Lys Asp Leu Ala 20 25 30 Arg Ser Val Ala Ser Ser Leu Leu Ser Ser Ser Glu Met Ala Phe Glu 35 40 45 Gln Glu Lys Glu Pro Asp Gly Glu Arg Trp His Asp Trp Ser Asp Pro 50 55 60 Tyr Arg Lys Trp Arg Thr Arg Lys Gly Asn Met Pro Gly Lys Ile Leu 65 70 75 80 Thr Leu Asn Gly Asp Leu Ala Arg Arg Leu Thr Thr Asp Tyr Gly Asp 85 90 95 Thr Trp Ala Leu Ile Gly Ser Asn Glu Pro Tyr Ala Ala Ile His Gln 100 105 110 Trp Gly Gly Leu Pro Gly Met Pro Pro Gly Pro Ala Ala Ile Gly Ala 115 120 125 Arg Pro Tyr Met Gly Phe Asp Gln Val Ala Glu Gln Glu Ile Met Asp 130 135 140 Glu Ile Arg Lys Arg Phe Lys Lys Ala Thr Glu Thr Pro * 145 150 155 <210> 723 <211> 375 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20649..21773) <400> 723 Met Lys Thr Lys Asn Thr Pro Lys Leu Ala Tyr Ala Ile Leu Asn Ala 1 5 10 15 Ile Ser Leu Ser Ala Asp Gly Asp Gly Asp Trp Cys Gln Ile Met Pro 20 25 30 Ala Gly Arg Val Lys Ala Arg Asp Gly Arg Pro Glu Lys Pro Ala Glu 35 40 45 Gly Trp Leu Ile Asn His Ala Ala Val Glu Arg Met Val Ser Arg Val 50 55 60 Val Ala Leu Asn Gln Pro Val Lys Ile Asp Tyr Asn His Gln Thr Leu 65 70 75 80 Ile Glu Gly His Pro Ala Pro Ala Ala Gly Phe Val Met Ala Ser Pro 85 90 95 Glu Asn Phe Arg Phe Ser Glu Glu Arg Gly Phe Glu Val Arg Pro Lys 100 105 110 Trp Asn Pro Pro Ala Leu Glu His Leu Arg Asn Asn Glu Phe Pro Trp 115 120 125 Phe Ser Pro Val Ile Gly Tyr Asp Glu Ser Thr Gly Glu Pro Val Glu 130 135 140 Leu Arg Met Leu Ala Ile Thr Gly Asp Pro Gly Leu Thr Gly Met Asn 145 150 155 160 Pro Val Ala Ala Leu Ser Ala Asp Asp Leu Tyr Asn Ala Leu Asn Pro 165 170 175 Pro Leu Lys Asp Thr Ser Met Asn Glu Gln Leu Arg Gln Leu Leu Thr 180 185 190 Ala Leu Gly Leu Thr Val Ala Asp Gly Asp Glu Phe Thr Pro Glu Leu 195 200 205 Gly Thr Ala Ala Leu Ser Ala Leu Thr Gly Ile Lys Thr Arg Ala Asp 210 215 220 Ala His Asp Asn Leu Lys Thr Gln Val Ala Ser Leu Ser Ala Glu Leu 225 230 235 240 Glu Thr Ala Lys Gly Thr Pro Ala Gly Gly Ile Ile Asp Leu Thr Lys 245 250 255 Tyr Val Pro Val Glu Thr Tyr Asn Ala Leu Arg Thr Glu Tyr Val Ala 260 265 270 Leu Ser Ala Gln His Gly Ser Thr Thr Leu Glu Gln Val Leu Asp Lys 275 280 285 Ala Glu Ser Glu Gly Arg Ile Phe Lys Ser Glu Arg Gly Tyr Leu Glu 290 295 300 Gln Leu Gly Gly Gln Ile Gly Val Ala Ala Leu Ser Ala Gln Leu Asp 305 310 315 320 Ala Arg Gln Pro Val Ala Ala Leu Thr Ser Leu Gln Thr Asp Thr Val 325 330 335 Thr Val Pro Asp Lys Lys Thr Ala Thr Ala Ala Leu Ser Ala Glu Asp 340 345 350 Ile Ala Ala Ala Lys Leu Leu Gly Lys Thr Glu Ala Glu Phe Leu Lys 355 360 365 Met Lys Glu Glu Met Gln * 370 <210> 724 <211> 316 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21773..22720) <400> 724 Met Pro Thr Pro Ile Thr Pro Ala Met Ile Thr Ala Leu Met Thr Gly 1 5 10 15 Tyr Arg Ser Asp Phe Gln Ala Gly Met Ser Met Ala Pro Ser Gln Tyr 20 25 30 Lys Lys Ile Ala Met Thr Val Pro Ser Thr Ser Lys Ser Asn Thr Tyr 35 40 45 Gly Trp Leu Gly Gln Phe Pro Gln Phe Arg Glu Trp Ile Gly Ser Arg 50 55 60 Val Ile Glu Lys Met Lys Ala Tyr Gly Tyr Ala Ile Val Asn Lys Thr 65 70 75 80 Phe Glu Gly Thr Val Ala Ile Ser Arg Asp Asp Phe Glu Asp Asp Asn 85 90 95 Leu Gly Ile Tyr Ser Pro Leu Phe Gln Glu Met Gly Arg Ala Ala Ala 100 105 110 Val Gln Pro Asp Glu Leu Val Phe Ala Ala Leu Arg Asp Gly Ile Ser 115 120 125 Ala Ala Cys Tyr Asp Gly Gln Asn Phe Phe Asp Thr Glu His Pro Val 130 135 140 Tyr Pro Lys Val Asp Gly Ser Gly Asp Ala Gln Met Val Ser Asn Met 145 150 155 160 Phe Val Ala Lys Thr Gly Ser Val Gly Ala Gln Ala Asp Tyr Ser Gly 165 170 175 Pro Ala Trp Tyr Leu Leu Asp Cys Ser Arg Ala Val Lys Pro Leu Ile 180 185 190 Tyr Gln Asp Arg Arg Lys Ala Glu Leu Val Ala Gln Thr Lys Val Asp 195 200 205 Glu Gly Arg Ala Phe Thr Asp Asn Glu Phe Val Phe Gly Ala Ser Ala 210 215 220 Arg Arg Asn Val Gly Tyr Gly Phe Trp Gln Met Ala Tyr Met Met Gln 225 230 235 240 Ser Pro Leu Thr Leu Asp Ala Leu Trp His Gly Trp Ser Ala Met Arg 245 250 255 Glu Phe Thr Ala Asp Gly Gly Arg Lys Leu Gly Ile Lys Pro Thr His 260 265 270 Ile Val Val Pro Thr Ser Leu Glu Lys Gln Ala Val Gln Leu Leu Glu 275 280 285 Arg Glu Leu Phe Ala Asp Gly Asn Ala Thr Val Ser Asn Glu Met Lys 290 295 300 Gly Lys Leu Glu Leu Val Val Ala Asp Tyr Leu * 305 310 315 <210> 725 <211> 129 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22764..23150) <400> 725 Met Asn Glu His His Thr Val Ala Ala Thr Asp Asp Ser Gly Leu Gln 1 5 10 15 Val Ser Gly Asp Asn Ser Val Thr Val Leu Ala Glu Val Arg Cys Ser 20 25 30 Arg Ser Ala Phe Arg Arg Ala Gly Phe Leu Phe Thr Arg Gly Arg Gln 35 40 45 Gln Val Glu Val Thr Pro Glu Gln Leu Ala Arg Leu Glu Glu Glu Pro 50 55 60 Cys Leu Thr Val Arg Ile Leu Gln Thr Ser Ala Asp Asp Ala Gly Ser 65 70 75 80 Val Ala Gly Val Val His Ala Val Ala Gly Thr Asp Leu Ala Glu Ala 85 90 95 Glu Ala Glu Ala Glu Ala Glu Ala Glu Ala Glu Ala Glu Ala Gly Gln 100 105 110 Asp Ala Pro Arg Lys Lys Thr Gly Asn Lys Ala Glu Gln Ala Arg Ala 115 120 125 * <210> 726 <211> 140 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23147..23566) <400> 726 Met Asn Tyr Ala Thr Glu Thr Asp Met Arg Ala Arg Tyr Arg Glu Asp 1 5 10 15 Leu Leu Arg Pro Leu Leu Ala Val Pro Arg Ser Asp Glu Pro Asp Thr 20 25 30 Arg Lys Leu Asn Arg Ala Leu Thr Asp Ala Ser Ala Leu Ile Asp Ser 35 40 45 Tyr Leu Ser Ala Arg Tyr Thr Leu Pro Leu Glu Val Ile Pro Ala Val 50 55 60 Leu Val Gln His Cys Cys Ala Ile Ala Phe Tyr Tyr Leu Cys Asp Gln 65 70 75 80 Arg Ala Ser Asp Gln Ala Arg Asp Arg Tyr Arg Glu Ala Leu Ala Trp 85 90 95 Leu Lys Asp Val Met Asn Gly Asn Val Pro Val Gly Val Asp Thr Asn 100 105 110 Gly Ala Ala Pro Glu Ser Gly Asp Leu Pro Gln Val Gln Ser Asp Ala 115 120 125 Ala Val Phe Gly Arg Asn Gln Lys Gly Phe Ile * 130 135 <210> 727 <211> 187 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23563..24123) <400> 727 Met Ile Thr Glu Thr Glu Gln Ala Tyr Ile Ala Arg Ile Arg Glu Tyr 1 5 10 15 Phe Gly Asn Glu Leu Val Ser Val Asp Thr His Pro Gly Asp Trp Ser 20 25 30 Asp Ser Val Leu Arg Thr Met Leu Ile Asn Ala Pro Ala Ile Tyr Val 35 40 45 Ala Trp Leu Gly Ala Gly Glu Gly Arg Thr Arg Gly Arg Leu Val Ser 50 55 60 His Trp Val Phe Tyr Val Ile Gly Asp Met Leu Asn Gly Arg Glu Ala 65 70 75 80 Ser Arg Pro Gly Leu Tyr Gln Ile Val Ala Arg Leu Ile Ala Val Leu 85 90 95 Asn Gly Phe Arg Thr Glu Lys Thr Ser Pro Leu Tyr Phe Glu Lys Ala 100 105 110 Val Asn Gly Tyr Thr Glu Thr Gln Ala Asp Ser Gly Ala Val Met Tyr 115 120 125 Ala Leu Tyr Phe Ser Cys Glu Glu Met Ile Ala Pro Leu Thr Asp Thr 130 135 140 Ser Ser Leu Asp Asp Phe Leu Arg His Tyr Glu Thr Phe Val Glu Pro 145 150 155 160 Pro Gly Thr Pro Pro Phe Glu Ala His Ile Asp Leu Pro Gly Asn Thr 165 170 175 Thr Thr Ala Val Glu Pro Pro Glu Glu Leu * 180 185 <210> 728 <211> 82 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24124..24369) <400> 728 Met Lys Thr Ile Phe Ile Lys Pro Ala Pro Gly Arg Leu Ile Arg Asp 1 5 10 15 Pro Asp Thr Met Arg Pro Leu Ala Gln Glu Gly Glu Glu Lys Pro Phe 20 25 30 Thr Pro Phe Trp Cys Arg Arg Leu Asp Asp Gly Asp Val Ile Gln Ala 35 40 45 Glu Lys Ala Ala Glu Glu Ala Pro Ala Val Ser Ala Asp Ala Thr Thr 50 55 60 Ala Thr Glu Lys Pro Val Ala Gln Pro Ala Ser Asp Lys Glu Lys Pro 65 70 75 80 Gln * <210> 729 <211> 501 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24366..25868) <400> 729 Met Ile Asn Phe Asp Gly Ile Gly Asn Asp Arg Arg Ile Pro Leu Ile 1 5 10 15 Glu Val Glu Phe Asn Asn Ser Met Ala Val Thr Gly Thr Pro Ala Gln 20 25 30 Arg Gln Cys Val Leu Leu Phe Gly Gln Ala Arg Met Lys Glu Asn Ala 35 40 45 Val Asp Gly Ala Gly Val Leu Asp Val Pro Val Arg Ile Thr Arg Ala 50 55 60 Ser Gln Ala Thr Glu Leu Trp Gly Arg Gly Ser Met Ile Ala Leu Met 65 70 75 80 Val Ala Glu Phe Ile Ala Ile Asn Pro Asp Ala Glu Leu Tyr Ala Ile 85 90 95 Ala Gln Gly Asn Gly Thr Gly Gln Ala Thr Ala Ala Ala Met Asn Leu 100 105 110 Thr Gly Thr Val Thr Arg Asp Gly Ile Val Tyr Ala Cys Val Gly Gly 115 120 125 Arg Arg Tyr Thr Leu Pro Ala Pro Lys Gly Lys Lys Gly Lys Glu Leu 130 135 140 Thr Asp Glu Leu Ala Ala Leu Ile Asn Ala Asp Pro Asp Ala Pro Phe 145 150 155 160 Thr Ala Ser Ser Gly Ala Gly Ser Gly Asp Asn Gly Ala Gly Leu Lys 165 170 175 Gly Ser Leu Gly Ile Thr Ala Arg Phe Thr Gly Glu Cys Ser Val His 180 185 190 Asp Val Arg Leu Asn Tyr His Asp Gly Glu Ala Thr Pro Glu Gly Ile 195 200 205 Gln Val Ala Ile Ala Tyr Pro Lys Gln Lys Ala Ala Asn Pro Asp Ile 210 215 220 Thr Arg Ser Val Ala Gly Met Gly Asp Arg Gln Tyr Asn Tyr Val Val 225 230 235 240 Met Pro Tyr Lys Asp Asp Ala Asn Leu Lys Ile Ile Ser Asp Glu Leu 245 250 255 Leu Lys Arg Trp Gly Pro Ala Lys Met Ser Asp Gly Val Leu Trp Leu 260 265 270 Ala His Thr Gly Thr Phe Gly Glu Val Gln Ala Phe Gly Ala Lys Arg 275 280 285 Asn Asp Phe Leu Ala Thr Cys Thr Ser Ile Pro Lys Ala Pro Glu Pro 290 295 300 Asp Tyr Leu Trp Ala Ala Ala Val Cys Ala Thr Cys Ala Pro Ser Leu 305 310 315 320 Gly Ala Asp Pro Ala Arg Pro Leu Gln Thr Leu Ala Leu Pro Ser Arg 325 330 335 Met Ala Pro Ala Pro Ala Asp Arg Leu Thr Arg Glu Glu Arg Asn Ser 340 345 350 Leu Leu Trp Gly Gly Ile Ala Thr Val Ser Val Ala Ala Gly Asp Val 355 360 365 Val Gln Ile Glu Arg Gln Val Thr Met Tyr Arg Gln Asn Val Tyr Gly 370 375 380 Glu Ser Asp Pro Ser Tyr Leu Asp Val Glu Thr Ile Tyr Thr Leu Ser 385 390 395 400 Trp Leu Arg Tyr Ser Leu Arg Thr Phe Ile Thr Gln Arg Phe Pro Arg 405 410 415 His Lys Leu Ala Asp Asp Gly Thr Pro Val Arg Ala Gly Gln Asn Ile 420 425 430 Val Thr Pro Glu Ile Met Lys Leu Gln Leu Ile Ser Leu Gly Glu Glu 435 440 445 Trp Val Glu Leu Gly Leu Val Glu Asn Leu Asp Thr Phe Lys Lys Asn 450 455 460 Leu Leu Val Glu Arg Asn Ala Ser Asp Arg Asn Arg Leu Asp Val Leu 465 470 475 480 Cys Thr Pro Asp Leu Val Asn Gln Phe Arg Phe Leu Ala Ala Gln Ile 485 490 495 Arg Phe Ile Leu * 500 <210> 730 <211> 122 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25877..26242) <400> 730 Met Ser Gly Lys Gln Tyr Gln Gly Thr Ala Thr Ile Arg Val Asn Gly 1 5 10 15 Gln Glu Tyr Glu Thr Leu Glu Gly Ala Thr Phe Ser Pro Ser Gly Phe 20 25 30 Glu Arg Glu Val Val Lys Gly Ala Lys Val Tyr Gly Tyr Arg Gln Lys 35 40 45 Pro Arg Glu Ala Thr Leu Asp Cys Lys Phe Pro Ala Gly Gly Glu Gly 50 55 60 Ser Pro Ala Ala Asp Glu Ile Asn Asn Trp Thr Ala Val Thr Ile Glu 65 70 75 80 Phe Val Ala Asp Thr Gly Glu Val His Met Met Thr Lys Ala Trp Ser 85 90 95 Ser Glu Pro Ala Ser Leu Asp Gly Gly Gly Glu Ile Ser Val Lys Phe 100 105 110 Ala Ser Ala Ser Ser Thr Arg Val Gln * 115 120 <210> 731 <211> 159 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26257..26733) <400> 731 Met Thr Thr Arg Lys Lys Lys Thr Ala Val Ser Glu Ala Ala Val Met 1 5 10 15 Glu Ala Ile Arg Glu Ala Leu Glu Gly Ala Asp Pro Arg Thr Ala Gly 20 25 30 Leu Thr Glu Gln Leu Ala Lys Gly Tyr Val Asp Leu Leu Asp Gly Leu 35 40 45 Pro Phe Gly Glu Thr Arg Glu Tyr Arg Val Thr Phe Arg Glu Leu Thr 50 55 60 Ala Lys Asp Ser Ile Asp Ala Glu Ala Glu Ala Glu Arg Val Val Glu 65 70 75 80 Thr Asn Asn Gly Pro Met Leu Ile Ala Ser Pro Ser Leu Arg Gly Val 85 90 95 Ala Leu Leu Arg Arg Gln Ile Ala Ala Val Gly Asp Ile Glu Gly Pro 100 105 110 Leu Ser Pro Arg Gln Ile Gly Gln Leu Ser Glu Arg Asp Leu Ser Arg 115 120 125 Leu Met Ala Ala Val Ser Leu Leu Asp Thr Ala Leu Ala Gly Lys Leu 130 135 140 Ala Ala Asp Arg Gly Arg Ser Gly Ala Val Ser Gly Ser Asp * 145 150 155 <210> 732 <211> 692 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26860..28935) <400> 732 Met Ala Arg Asn Leu Arg Ala Ser Leu Ile Val Asp Leu Leu Gly Asn 1 5 10 15 Ile Ser Ala Lys Ser Arg Gln Trp Ser Gln Glu Leu Gly Ala Phe Ser 20 25 30 Arg Ser Gly Gln Ala Gly Leu Gly Gly Leu Gly Asn Ala Ala Arg Arg 35 40 45 Ala Gly Gln Glu Thr Asp Val Leu Gly Ser Arg Met Gln Arg Thr Leu 50 55 60 Ala Gly Val Arg Gly Ser Ile Arg His Val Thr Ser Asp Phe Asp Arg 65 70 75 80 Leu Gln Gly Ser Ile Thr Gly Thr Ile Gly Arg Ile Ser Asn Leu Tyr 85 90 95 Gly Met Leu Ala Gly Gly Ala Ala Val Tyr Gly Phe Asn Arg Gly Phe 100 105 110 Ile Arg Pro Ala Ala Glu Met Glu Thr Tyr Met Ile Arg Leu Asn Ser 115 120 125 Leu Tyr Lys Gly Asp Arg Ala Lys Thr Asp Asp Val Arg Arg Trp Ala 130 135 140 Ile Gln Asn Ala Lys Glu Thr Thr Trp Gly Leu Ala Gly Val Met Gln 145 150 155 160 Glu Tyr Thr Ser Ser Leu Gly Phe Gly Met Ser Asp Arg Glu Ala Arg 165 170 175 Asn Phe Val Thr Met Leu Gln Asp Gln Gly Ala Val Gly Gly Trp Ser 180 185 190 Leu Ser Asp Ala Gln Gly Ala Ser Leu Gln Leu Lys Gln Met Tyr Ala 195 200 205 Arg Gly Ser Ile Gln Ala Ala Asp Ala Asn Ile Leu Ala Thr Tyr Gly 210 215 220 Ile Asn Ala Tyr Arg Val Leu Ala Asp Arg Leu Gly Val Asp Gln Lys 225 230 235 240 Val Val Arg Lys Leu Gly Glu Lys Gly Leu Leu Gly Pro Asp Ser Ile 245 250 255 Arg Leu Leu Phe Gln Thr Leu Ala Glu Gln Ala Arg Gly Ala Gln Lys 260 265 270 Asp Ala Met Asn Ser Trp Ser Gly Leu Thr Ala Met Met Gly Asp Val 275 280 285 Trp Asp Gln Phe Ala Arg Asp Val Met Asp Ser Gly Pro Phe Glu Lys 290 295 300 Leu Lys Gly Asn Leu Arg Gly Phe Leu Ser Trp Val Asp Ser Ala Lys 305 310 315 320 Ser Asp Gly Ser Tyr His Ser Leu Ala Glu Ser Thr Ala Ser Ala Met 325 330 335 Asn Gln Gly Phe Glu Tyr Ala Arg Asp Ala Val Thr Gly Phe Tyr Gln 340 345 350 Ala Ile Arg Lys Val Arg Asp Thr Leu Gln Ala Leu Arg Asp Ala Gly 355 360 365 Tyr Gly Asp Ala Leu Asp Arg Ile Gly Gln Gly Ala Gln Thr Ala Ala 370 375 380 Lys Tyr Leu Leu Tyr Met Tyr Leu Ala Thr Arg Ala Leu Lys Met Ala 385 390 395 400 Arg Ala Val Gly Thr Gly Ile Ile Arg Pro Gly Ala Ala Leu Leu Gly 405 410 415 Tyr Gly Leu Ser Ala Ala Ala Phe Leu Thr Ser Pro Phe Arg Arg Ser 420 425 430 Pro Pro Ala Gly Thr Pro Pro Gly Thr Tyr Gln Gly Arg Gly Gln Arg 435 440 445 Phe Ile Asn Phe Leu Thr Gly Val Asn Pro Ala Ala Val Gln Pro Val 450 455 460 Leu Val Thr Asn Trp Pro Thr Gly Gly Leu Ser Gly Thr Gly Ala Thr 465 470 475 480 Asp Thr Ser Ser Gly Gly Arg Gln Gly Arg Gly Arg Arg Lys Arg Gly 485 490 495 Pro Gly Arg Gly Arg Pro Val Thr Pro Pro Leu Pro Pro Ser Pro Val 500 505 510 Pro Pro Ser Pro Ser Ser Gly Gly Ala Gly Phe Trp Gly Arg Met Met 515 520 525 Gly Arg Ala Gly Gly Leu Leu Ser Ser Val Gly Ser Arg Met Gly Leu 530 535 540 Gly Arg Phe Ser Gly Phe Phe Arg Ser Ala Gly Gly Leu Ala Gly Arg 545 550 555 560 Leu Gly Gly Gly Ala Leu Trp Ala Gly Ala Met Ala Ala Pro Val Leu 565 570 575 Leu Asp Gly Ser Ala Ser Ala Thr Asp Lys Gly Glu Ala Val Gly Ser 580 585 590 Leu Ala Gly Ser Ile Ala Gly Gly Ala Leu Gly Ala Ala Ala Gly Pro 595 600 605 Val Gly Ile Ala Ile Gly Ser Thr Val Gly Ser Tyr Leu Gly Asn Tyr 610 615 620 Leu Gly Gly Trp Leu Thr Glu Ala Trp Gln Lys Leu Arg Gly Ser Asp 625 630 635 640 Asp Glu Ser Ser Gly Gln Ala Val Gln Lys Ala Ser Ala Arg Val Glu 645 650 655 Leu Val Ala Pro Glu Gly Trp Gln Ala Arg Ser Ile Asp Ile Asp Asp 660 665 670 Thr Ser Gly His Gly Leu Asp Val Asn Val Trp Asn Gly Gly Asn Tyr 675 680 685 Gly Leu Trp * 690 <210> 733 <211> 457 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28901..30271) <400> 733 Met Ser Gly Thr Glu Gly Ile Met Ala Ser Gly Asp Gly Arg Gly Ala 1 5 10 15 Phe Arg Gly Val Pro Phe Leu Val Trp Arg Glu Gln Arg Glu Arg Gly 20 25 30 Gly Arg Asn Ile Val Arg Arg Glu Tyr Pro Leu Arg Glu Thr Gly Gly 35 40 45 Ala Asp Asp Leu Gly Pro Lys Leu Ala Glu Phe Thr Phe Ser Val Leu 50 55 60 Val Met Gly Asp Asp Val Gln Thr Gln Arg Asn Arg Leu Arg Asp Ala 65 70 75 80 Leu Arg Ala Pro Gly Ala Gly Glu Leu Leu His Pro Asp Tyr Gly Thr 85 90 95 Leu Asn Val Leu Ile Asn Ser Phe Glu Ser Arg Tyr Asn Ala Ala Glu 100 105 110 Gln Gly Val Val Glu Phe Thr Ile Asn Val Thr Pro Val Ser Asp Asp 115 120 125 Thr Ala Pro Ala Val Thr Gln Asp Thr Ala Ala Ile Leu Glu Gln Lys 130 135 140 Ser Thr Thr Ala Leu Gly Lys Val Phe Glu Thr Leu Glu Ala Gly Trp 145 150 155 160 Thr Val Ile Ser Asp Gly Met His Asp Val Gln Ala Met Thr Glu Thr 165 170 175 Ile Ser Asp Lys Val Ser Ala Leu Glu Asn Ala Val Ser Gly Met Gly 180 185 190 Ile Val Gln Asp Ile Ser Ala Phe Thr Ala Thr Phe Thr Ala Leu Lys 195 200 205 Gly Asn Ala Thr Ala Leu Leu Thr Ala Pro Ser Arg Met Ala Ser Ser 210 215 220 Phe Ala Gly Leu Phe Ser Ala Leu Ile Thr Leu Pro Ser Leu Pro Ser 225 230 235 240 Leu Ser Ser Gly Gly Leu Asn Thr Arg Pro Gly Gly Ser Ile Gly Arg 245 250 255 Thr Thr Ser Ala Phe Ser Gln Gly Met Pro Gln Leu Tyr Arg Thr Leu 260 265 270 Ser Ser Leu Arg Tyr Val Leu Asp Glu Gln Asp Asn Pro Gln Thr Leu 275 280 285 Ile Gly Leu Thr Pro Ala Ala Gln Lys Asn Ile Arg Leu Ile Arg Ala 290 295 300 Val Met Gln Ser Ala Ala Val Val Ala Gln Ala Gln Thr Val Gly Lys 305 310 315 320 Leu Leu Asp Gln Val Leu Ser Gln Glu Thr Leu Pro Asp Ser Asp Ala 325 330 335 Ala His Arg Thr Trp Pro Val Trp Leu Glu Ser Ser Val Asp Leu Gln 340 345 350 Arg Ile Asn Arg Asp Leu Ser Glu Ala Leu Glu Arg Gln Val Met Thr 355 360 365 Leu Ser Gly Gln Gly Tyr Thr Ala Thr Ala Leu Thr Leu Arg Asp Ala 370 375 380 Arg Leu Ala Leu Thr Glu Asp Leu Asn Thr Arg Gly Val Gln Leu Pro 385 390 395 400 Gly Ala Thr Val Val Thr Val Arg Thr Thr Glu Pro Ala Leu Val Thr 405 410 415 Leu Tyr Arg Ala Thr Gly Asn Ser Thr Gly Trp Gln Arg Phe Val Arg 420 425 430 Arg Asn Gly Ile Val Asp Pro Leu Phe Ile Pro Gly Gly His Ser Val 435 440 445 Glu Val Ile Ser Glu Gln Gln Gly * 450 455 <210> 734 <211> 375 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30255..31379) <400> 734 Val Ser Ser Arg Val Glu Leu Tyr Leu Gly Gly Glu Ile Phe Ser Gly 1 5 10 15 Trp Leu Thr Val Ser Val Arg Arg Ser Leu Glu His Leu Ala Gly Ser 20 25 30 Phe Glu Leu Gly Val Met Met Pro Gly Val Arg Leu Pro Ser Ser Val 35 40 45 Arg Ala Gly Gln Ser Leu Glu Leu Arg Ile Asp Gly Gln Pro Val Ile 50 55 60 Thr Gly Trp Leu Asp Gln Val Arg Gln Arg Ile Ser Ala Thr Arg Phe 65 70 75 80 Gln Ile Thr Leu Ser Gly Arg Asp Lys Thr Gly Asp Leu Val Asp Cys 85 90 95 Ser Ala Ile His Pro Gly Ser Gln Trp Arg Asn Arg Thr Leu Glu His 100 105 110 Ile Ala Ser Asp Leu Cys Ala Pro Phe Gly Val Thr Val Arg Trp Gln 115 120 125 Val Asn Asp Ala Thr Ala Ala Arg Pro Phe Ser Thr Phe Thr Leu Glu 130 135 140 Asn Ser Glu Thr Val Ala Asp Ala Leu Thr Arg Ala Ala Arg His Arg 145 150 155 160 Gly Val Leu Val Thr Ser Asn Ala Ala Gly Glu Leu Val Phe Thr Gln 165 170 175 Ala Gly Ser Gln Arg Gly Asp Thr Leu Thr Leu Gly Glu Asn Leu Leu 180 185 190 Asp Leu Asp His Asn Val Asp His Arg Leu Arg His Ser Glu Tyr Arg 195 200 205 Val Arg Gly His Gly Arg Gly Gly Gly His Ala Gly Asp Ala Leu Thr 210 215 220 Ala Gly Thr Leu Ala Ala Pro Val Gly Thr Val Thr Asp Ser Ala Ile 225 230 235 240 His Arg Tyr Arg Pro Lys Ile Val Leu Ala Asp His Ala Val Asp Ala 245 250 255 Asp Gly Ala Arg Gln Arg Ala Val Arg Glu Met Arg Arg Ala Val Ala 260 265 270 Arg Ser Val Arg Leu Thr Ala Thr Val Arg His Trp Phe Arg Glu Asn 275 280 285 Gly Gln Leu Trp Asp Ile Asn Leu Leu Thr Ala Val Thr Ala Pro Arg 290 295 300 Thr Gly Val Glu Glu Arg Asp Leu Leu Val Cys Gln Val Glu Phe Ser 305 310 315 320 Leu Asp Ala Asn His Gly Glu Thr Thr Arg Leu Ile Leu Ala Pro Arg 325 330 335 Asp Gly Phe Ile Val Pro Ala Glu Pro Gly Asn Ser Gly Ser Gly Asn 340 345 350 Ala Gly Asp Val Asp Ala Phe Val Arg Ala Gln Met Lys Lys Gln Gly 355 360 365 Ile Lys Phe Asn Asp Glu * 370 <210> 735 <211> 205 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31369..31983) <400> 735 Met Met Asn Asp Glu Val Ile Ser Arg Leu Leu Ala Pro Val Met Arg 1 5 10 15 Gly Val Arg Leu Leu Phe Gly Arg Gly Val Leu Thr Gly Thr Thr Asp 20 25 30 Thr Leu Lys Ile Gln Asn Val Gln Ile Thr Gly Met Asp Gly Glu Thr 35 40 45 Phe Asp Asp Val Glu Arg Pro Gln Gln Tyr Gly Gln Ile Ser Val Pro 50 55 60 Leu Pro Gly Ala Glu Val Phe Leu Ala Cys Ala Gly Gly Gln Arg Asp 65 70 75 80 Gln Ala Val Val Leu Val Val Glu Asp Arg Arg Ser Arg Pro Thr Gly 85 90 95 Leu Thr Ala Gly Asp Thr Gly Val Tyr His His Glu Gly His Arg Ile 100 105 110 Arg Leu Thr Lys Asn Gly Arg Ile Ile Val Thr Cys Lys Thr Leu Glu 115 120 125 Ile Tyr Ala Asp Glu Gly Val Gln Val Asp Thr Pro Glu Ala His Phe 130 135 140 Thr Gly Asn Val Thr Val Asp Lys Asn Leu His Val Lys Gly Asn Val 145 150 155 160 Ser Ile Asp Gly Thr Gly Arg Ser Gln Gly Thr Phe Thr Met Ser Glu 165 170 175 Ala Val Ile Ala Gly Ile Thr Tyr Ser Gly His Val His His Asp Asn 180 185 190 Gly Glu Gly Ser Lys Arg Gly Gly Pro Glu Asn Gly * 195 200 <210> 736 <211> 146 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31976..32413) <400> 736 Met Ala Asp Ile Ala Val Val Trp Asp Gln Gly Cys Gly Ser Leu Gln 1 5 10 15 Leu Asn Gly Ala Asp Leu Leu Thr Asp Asn Ser Leu Leu Thr Ala Val 20 25 30 Ile Ile Ser Leu Phe Thr Asp Arg Arg Ala Leu Asp Ser Asp Glu Ile 35 40 45 Pro Asp Gly Thr Arg Asp Arg Arg Gly Trp Trp Gly Asp Ser Phe Arg 50 55 60 Glu Arg Pro Val Gly Ser Arg Leu Trp Leu Leu Ser Arg Glu Lys Thr 65 70 75 80 Leu Ser Ser Val Val Ser Arg Ala Gln Ala Tyr Ala Asp Glu Ala Leu 85 90 95 Ala Trp Leu His Lys Ser Gly Ala Ala Thr Ser Val Val Cys His Ala 100 105 110 Met Arg Val Gly His Ala Arg Leu Ser Leu Ser Val Lys Ile Thr Leu 115 120 125 Pro Asp Gly Ser Arg His Pro Met Ile Phe Tyr Ala Asp Met Lys Gly 130 135 140 Glu * 145 <210> 737 <211> 362 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32410..33495) <400> 737 Met Met Pro Tyr Gln Pro Leu Pro Leu Ala Gln Leu Ile Thr Gln Thr 1 5 10 15 Gln Gln Asp Ile Ser Gln Arg Leu Pro Gly Ser Gln Pro Gly Val Asn 20 25 30 Glu Thr Thr Leu Asn Ala Ile Ala Tyr Ala Leu Ala Gly Leu Ser Ala 35 40 45 Gln Glu His Glu His Leu Ala Trp Ile Ser Arg Gln Ile Ile Pro Thr 50 55 60 Glu Ala Asp Glu Ala Glu Leu Leu Lys His Cys Ala Phe Trp Gly Val 65 70 75 80 Ile Arg Lys Pro Ala Ser Arg Ala Asp Gly Pro Val Gln Leu Met Leu 85 90 95 Thr Thr Asp Ala Gly Ile Thr Glu Gly Val Leu Leu Gln Arg Ser Asp 100 105 110 Gly Val Val Tyr Arg Ile Thr Gly Ser Ala Thr Gly Lys Ala Gly Thr 115 120 125 Leu Asn Val Asn Val Glu Ala Glu Ser Ala Gly Arg Ala Gly Asn Thr 130 135 140 Pro Thr Gly Thr Arg Leu Ser Phe Ile Thr Pro Gln Ala Gly Ile Asn 145 150 155 160 Gln Thr Ala Thr Val Thr Gly Thr Gly Leu Thr Gly Gly Ala Asp Val 165 170 175 Glu Thr Val Pro Glu Leu Leu Ser Arg Leu Val Phe Arg Val Gln Asn 180 185 190 Pro Pro Ser Gly Gly Thr Gln Tyr Asp Phe Glu Arg Trp Ala Arg Glu 195 200 205 Val Pro Gly Val Thr Arg Ala Trp Cys Lys Pro Glu Trp Pro Glu Ala 210 215 220 Gly Ser Val Gly Val Thr Phe Val Gln Asp Asn Asn Pro Asp Ile Phe 225 230 235 240 Pro Gly Glu Gly Asp Val Lys Arg Val Ala Asp Tyr Ile Arg Ser His 245 250 255 Asp Asp Pro Ala Thr Gly Gln Pro Val Gly Gln Pro Leu Gly Pro Thr 260 265 270 Ile Ser Val Phe Lys Leu Thr Asn Lys Pro Val Ala Phe Glu Ile Arg 275 280 285 Ile Val Pro Lys Thr Pro Glu Asn Gln Ala Ala Val Lys Gln Ala Leu 290 295 300 Thr Asp Leu Leu Tyr Asn Glu Ser Arg Pro Gly Gly Leu Val Leu Pro 305 310 315 320 Ser Ser Phe Trp Arg Ala Val Ala Gly Val Lys Gly Leu Glu Asp Phe 325 330 335 Glu Val Arg Ser Pro Leu Lys Ser Val Met Ala Gly Asp Thr Glu Leu 340 345 350 Leu Thr Val Gly Glu Ile Thr Trp Leu * 355 360 <210> 738 <211> 187 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33486..34046) <400> 738 Met Ala Val Thr Leu Thr Pro His Gln Arg Ala Leu Leu Gln Leu Leu 1 5 10 15 Pro Asp Gly Leu Ala Trp Asp Lys Arg Pro Ser Ser Val Leu Ala Ala 20 25 30 Leu Cys Leu Gly Leu Ser His Ser Thr Glu Arg Val Ser Trp Thr Gly 35 40 45 Asn Gln Met Leu Ala Glu Arg Phe Pro Asp Ser Ser Arg Leu Leu Leu 50 55 60 Glu Asp Trp Glu Arg Tyr Leu Gly Leu Pro Glu Cys Asp Met Thr Gly 65 70 75 80 Ala Thr Ile Gln Glu Arg Gln Arg Tyr Ala Gly Asn Lys Tyr Arg Met 85 90 95 Lys Pro Ser Leu Asn Arg Glu Phe Tyr Ile Arg Phe Ala Ala Glu Phe 100 105 110 Gly Tyr Glu Ile Asp Ile Gln Pro Ser Pro Asp Ser Gln Trp Val Ser 115 120 125 Ile Val Thr Ile Asn Ser Glu Thr Gly Tyr Arg Asn Met Asn Val Leu 130 135 140 Asp Asp Ile Leu Thr Pro Leu Arg Ile Tyr Glu Gly Gly Ala Leu Glu 145 150 155 160 Cys Ile Leu Asn Arg Tyr Lys Pro Ala Trp Gln Thr Phe Ile Tyr Val 165 170 175 Tyr Ala Asn Ser His Glu Glu Glu Asn Ile * 180 185 <210> 739 <211> 304 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34046..34957) <400> 739 Met Phe His Val Asp Asn Asn Ser Gly Val Ala Asn Met Pro Ala Leu 1 5 10 15 Ala Pro Ala Gln Ser Asn Thr Thr Thr Trp Phe Thr Glu Gly Asp Gly 20 25 30 Gln Lys Gly Ile Ser Trp Ile Gly Gln Asp Trp Leu Asn Ile Leu Gln 35 40 45 Ala Glu Leu Leu Asn Ile Leu Ala Glu Ala Ser Ile Gln Pro Asp Lys 50 55 60 Ala Gln Leu Asn Gln Leu Thr Leu Ser Ile Lys Ala Ile Ile Ala Ala 65 70 75 80 Asn Ala Phe Ser Arg Lys Asn Asn Leu Lys Glu Ile Ala Asp Ala Gly 85 90 95 Ala Glu Ala Gln Arg Leu Ala Arg Gly Tyr Leu Gly Leu Gly Ala Leu 100 105 110 Ala Thr Lys Asn Ser Leu Gly Pro Gly Asp Val Asn Ala Leu Ala Lys 115 120 125 Asp Gln Asn Leu Ala Asp Leu Glu Asn Ala Gly Thr Ala Arg Asn Asn 130 135 140 Leu Asp Val Tyr Ser Lys Ser Glu Gly Asp Asn Arg Tyr Leu Arg Arg 145 150 155 160 Glu Gln Asn Gly Ala Asp Ile Pro Asp Lys Gly Ala Phe Ile Asp Asn 165 170 175 Val Gly Leu Arg Glu Thr Val Asn Lys Ala Ala Asp Ala Leu Pro Ser 180 185 190 Gly Gly Thr Ala Val Ala Ala Asn Arg Leu Ala Thr Pro Arg Asn Ile 195 200 205 Asn Gly Val Pro Phe Asp Gly Thr Leu Asp Ile Asn Ile Thr Ser Gly 210 215 220 Met Thr Gln Ser Thr Ala Asp Gly Arg Tyr Val Gln Asn Val Gln Leu 225 230 235 240 Gly Ala Gln Ser Tyr His Ser Pro Gly Gly Asn Glu Met Ser Trp Asn 245 250 255 Tyr Ser Ala Pro Ser Gly Cys Met Leu Ser Gly Ile Asn Val Gln Glu 260 265 270 Thr Gly Ser Arg Ser Ala Asp Asn Ile Gly Gly Val Tyr Tyr Arg Pro 275 280 285 Val Gln Ile Tyr Ile Asn Asn Ala Trp Arg Thr Val Ser Ser Val * 290 295 300 <210> 740 <211> 174 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34992..35513) <400> 740 Met Glu Leu Ile Asn Val Lys Arg Tyr Tyr Pro Glu His Lys Pro Tyr 1 5 10 15 Gly Glu Asp Val Gln Tyr Phe Gln Ser Glu Asp Gly Arg Asp Phe Tyr 20 25 30 Glu Ser Ile Pro Leu Phe Thr Lys Lys Tyr Lys Leu Cys Ile Ser Pro 35 40 45 Val Thr Gly Ile Ile Cys Ser Val Ala Glu Asp Val Ser Ala Leu Tyr 50 55 60 Pro Ala Gly Phe Thr Val Val Glu Val Asp Glu Leu Pro Glu Gly Val 65 70 75 80 Asn Ile Asp Gly Asn Trp Gln Phe Ser Asp Gly Leu Ile Ser Lys Val 85 90 95 Pro Val Asn Trp Lys Thr Val Ala Glu Lys Arg Arg Ser Ser Leu Leu 100 105 110 Gln Glu Ala Asn Glu Thr Val Asp Asp Trp Lys Thr Glu Leu Lys Leu 115 120 125 Asp Met Ile Ser Asp Glu Asn Lys Leu Gln Leu Thr Arg Trp Met Ala 130 135 140 Tyr Ile Arg Gln Leu Lys Glu Met His Phe Asn Asp Ile Ala Ser Glu 145 150 155 160 Gly His Tyr Gln Ala Ile Pro Trp Pro Glu Lys Pro Glu * 165 170 <210> 741 <211> 68 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35593..35796) <400> 741 Val Ala Asp Ser Arg Tyr Val Gln Ser Ile Arg Arg Gly Ser Arg Ser 1 5 10 15 Thr Ile Gly Met Gln Tyr Asn Ile Phe Glu Val Pro Asp Gly Cys Val 20 25 30 Leu Thr Gly Leu Asp Val Ala Gly Asp Gly Asn Ala Thr Val Thr Ala 35 40 45 Tyr Tyr Arg Pro Val Gln Phe Leu Ile Asp Gly Ser Trp Lys Thr Ala 50 55 60 Ser Ser Ala * 65 <210> 742 <211> 187 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36018..36578) <400> 742 Met Leu Ile Gly Tyr Ile Arg Val Ser Thr Asn Asp Gln Asn Thr Gly 1 5 10 15 Leu Gln Arg Asn Ala Leu Glu Cys Ala Gly Cys Glu Gln Ile Phe Glu 20 25 30 Asp Lys Met Ser Gly Lys Thr Thr Gln Arg Pro Gly Leu Lys Arg Ala 35 40 45 Leu Lys Lys Leu Lys Pro Gly Asp Thr Leu Met Val Trp Lys Leu Asp 50 55 60 Arg Leu Gly Arg Ser Met Arg His Leu Val Ala Leu Thr Asp Glu Leu 65 70 75 80 Gln Gln Gln Gly Ile Asn Phe Arg Ser Leu Thr Asp Asn Ile Asp Thr 85 90 95 Ser Thr Pro Met Gly Arg Phe Phe Phe His Ile Met Gly Ala Leu Ala 100 105 110 Glu Met Glu Arg Glu Leu Ile Val Glu Arg Thr Arg Ala Gly Leu Ala 115 120 125 Ala Ala Arg Glu Arg Gly Arg Thr Gly Gly Arg Pro Arg Arg Leu Thr 130 135 140 Gln Glu Gln Tyr Glu Gln Val Gly Arg Leu Leu Ala Gly Gly Val Ser 145 150 155 160 Arg Arg Gln Val Ala Leu Ile Phe Asp Ile Gly Leu Ser Thr Leu Tyr 165 170 175 Arg Tyr Tyr Pro Ala Ser Val Ser Glu Lys * 180 185 <210> 743 <211> 680 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36678..38717) <400> 743 Met Thr Ser Lys Trp Val Gln Leu Ser Ser Met Pro Gly Asn Phe Thr 1 5 10 15 Val Lys Val Ser Gly Gly Thr Ala Ala Phe Leu Glu Ala Pro Phe Pro 20 25 30 Pro Ala Glu Thr Lys Gly Gly Met Thr Phe Ala Asp Cys Leu Ile Ser 35 40 45 Phe Asn Thr Arg Asp Cys Leu Trp Val Arg Pro Val Ser Gly Asp Pro 50 55 60 Ser Val Glu Ile Thr Gly Ala Gly Ile Gly Ala Val Ile Pro Leu Ser 65 70 75 80 Ala Asp Val Ala Gly Thr Ala Glu Pro Ser Asp Trp Asp Asn Ala Glu 85 90 95 Thr His Thr Arg Pro Ser Gly Asn Glu Thr Ala Ser Ser Ser Pro Ser 100 105 110 Trp Tyr Tyr Val Val Val Leu Ala Gly Gln Ser Asn Gly Met Ala Tyr 115 120 125 Gly Glu Gly Leu Pro Leu Pro Glu Thr Tyr Asp Arg Pro Glu Pro Arg 130 135 140 Ile Met Gln Leu Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Lys Ala 145 150 155 160 Cys Gln Tyr Asn Asp Ile Ile Leu Ala Asp His Cys Leu His Asp Val 165 170 175 Gln Asp Met Ser Gly Lys Asn His Pro Lys Ala Asp Val Ala Lys Gly 180 185 190 Gln Tyr Gly Thr Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu 195 200 205 Pro Phe Ile Pro Ala Asp Ala Gly Ile Leu Leu Val Pro Cys Cys Arg 210 215 220 Gly Gly Ser Ala Phe Thr Ala Gly Ala Asp Gly Thr Tyr Ser Asp Ser 225 230 235 240 Thr Gly Ala Ser Glu Asp Ser Ala Arg Trp Gly Val Asp Lys Pro Leu 245 250 255 Tyr Lys Asp Leu Ile Ser Arg Thr Lys Ala Ala Leu Ala Lys Asn Pro 260 265 270 Lys Asn Arg Leu Leu Ala Val Val Trp Met Gln Gly Glu Phe Asp Ile 275 280 285 Asp Ala Lys Pro Thr Glu His Ser Ala Leu Phe Leu Ala Met Val Glu 290 295 300 Lys Phe Arg Ala Asp Leu Ala Glu Gln Ala Glu Gln Cys Thr Gly Gly 305 310 315 320 Ser Ala Ala Gly Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Phe Trp 325 330 335 Lys Gln Lys Asn Glu Pro Ala Tyr Gln Ala Ile Tyr Gly Gly Tyr Lys 340 345 350 Asn Lys Thr Asp Lys Asn Ile His Phe Val Pro Leu Met Thr Asp Glu 355 360 365 Asn Asp Ala Asn Val Pro Thr Asn Asn Pro Ala Glu Asp Pro Asp Ile 370 375 380 Glu Ser Ile Gly Tyr Tyr Gly Ser Thr Trp Arg Asn Ser Ala Ala Thr 385 390 395 400 Trp Thr Ser Ala Asp Arg Ala Ser His Phe Ser Ser Trp Ala Arg Arg 405 410 415 Gly Ile Ile Ser Asp Arg Leu Ala Thr Ala Val Leu Thr His Ala Gly 420 425 430 Arg Thr Thr Val Lys Ala Asp Val Pro Ser Ser Glu Thr Glu Ala Pro 435 440 445 Val Pro Ser Pro Ser Glu Thr Glu Ala Val Thr Thr Thr Leu Leu Ser 450 455 460 Tyr Arg Val Ser Glu Ser Glu Gly Asn Leu Lys Ala Gln Gly Trp Glu 465 470 475 480 Pro Ala Gly Gly Lys Ala Glu Ile Ile Ser Asp Ala Gly Gly Thr Gly 485 490 495 Gly Lys Ala Met Lys Leu Thr Lys Glu Thr Gly Lys Ser Ser Trp Tyr 500 505 510 Leu Asp His Asp Ala Gly Thr Gly Ala Glu Leu Leu Lys Asn Gly Gly 515 520 525 Leu Ile Ser Cys Arg Phe Lys Val Pro Gly Asp Leu Val Ala Asn Gln 530 535 540 Tyr Val Met Gly Leu Tyr Trp Pro Val Ser Ser Leu Pro Gln Gly Val 545 550 555 560 Thr Leu Thr Gly Asp Ala Gly Asn Asn Leu Leu Ala Ser Phe Tyr Ile 565 570 575 Gln Thr Asp Ala Lys Asp Leu Asn Val Met Tyr His Asn Ala Lys Val 580 585 590 Ala Thr Asn Asn Gln Lys Leu Gly Thr Phe Gly Ala Phe Asp Asn Glu 595 600 605 Trp His Thr Leu Ala Phe Arg Phe Ala Gly Asn Asn Ser Leu Gln Val 610 615 620 Ile Pro Val Ile Asp Gly Gln Asp Gly Ala Ala Phe Thr Leu Thr Gln 625 630 635 640 Ser Pro Val Gly Thr Phe Pro Val Asp Lys Leu Arg Val Thr Asp Ile 645 650 655 Thr Lys Asn Ala Thr Tyr Pro Val Leu Ile Asp Ser Ile Val Val Glu 660 665 670 Val Lys Lys Ala Val Thr Glu * 675 <210> 744 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38864..39046) <400> 744 Met Thr Phe Val His Thr Met Leu Leu Tyr Phe Cys Ala Val Val Ser 1 5 10 15 Ala Leu Tyr Leu Val Ser Gly Gly Tyr Lys Val Ile Arg Asn Tyr Ile 20 25 30 Arg Arg Lys Ile Asp Asp Ala Ala Ala Glu Lys Leu Ser Lys Thr Ala 35 40 45 Gln Ala Pro Ser Ser Pro Asn Asp Pro Thr Pro Leu * 50 55 60 <210> 745 <211> 82 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39082..39327) <400> 745 Met Pro Glu Ile Lys Gly Thr Val Thr Glu Glu Leu Val Lys Gln Ala 1 5 10 15 Leu Tyr Ser Glu Glu Val Asn Arg Val Leu Lys Ala Gln Val Arg Lys 20 25 30 Asp Phe Glu Ala Gln Ile Asp Ala Tyr Val Asp Glu Val Leu Ala Arg 35 40 45 Met Val Gly Arg Ser Pro Ala Glu Asn Ser Thr Glu Asn Asp Pro Gln 50 55 60 Pro Val Glu Gln Pro Glu Pro Val Gln Pro Gly Thr Asp Gly Thr Met 65 70 75 80 Met * <210> 746 <211> 104 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39366..39677) <400> 746 Val Lys Pro Ser Ile Ala Gly Thr Met Leu Gly Gln Ser Val Lys Thr 1 5 10 15 Cys Ile Asn Ala Leu Leu Arg Ala Arg Gly Val Ser Tyr Asp Ile Pro 20 25 30 Arg Ser Pro Val Lys Gln Arg Cys Ile Lys Arg Arg Ser Leu Ser Trp 35 40 45 Met Lys Glu Pro Val Cys Pro Ala Cys Lys Thr Pro Leu Gln Leu Ile 50 55 60 Tyr Arg Arg Ser Arg Ser Gln Asn Gly Lys Thr Tyr Lys Pro Lys Asn 65 70 75 80 Ala Ser Cys Phe Arg Met Leu Ile Cys Pro Ala Cys Ser Pro Arg Arg 85 90 95 Glu Asn Thr Gln Asn Val His * 100 <210> 747 <211> 67 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39945..40145) <400> 747 Met Tyr Arg Asn Ile Arg Cys Arg His Cys Asn Lys Leu Leu Ala Arg 1 5 10 15 Ala Ser Phe Ser Tyr Leu Glu Val Lys Cys Pro Arg Cys Lys Thr Leu 20 25 30 Asn Gln Ile Thr Ser Pro Ser Ala Thr Glu His Pro Thr Tyr Thr Arg 35 40 45 Lys Ser Cys Arg Gly Glu Gln Lys Ala Ser His Ile Pro Asn His Gln 50 55 60 His Ala * 65 <210> 748 <211> 246 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40099..40836) <400> 748 Val Gly Asn Arg Lys Gln Val Thr Ser Arg Ile Ile Ser Thr Pro Glu 1 5 10 15 Leu Ile Arg Tyr Asn Asp Asn Ile Val Gly Tyr Gly Ser Arg Glu Leu 20 25 30 Arg Val Glu Thr Ile Ser Cys Trp Leu Ala Arg Leu Val Ile Val Asn 35 40 45 Lys His Tyr Ser His Arg Phe Val Asn Asn Ser Tyr Leu His Leu Gly 50 55 60 Ile Phe Ser Glu Arg Glu Leu Val Gly Val Met Gln Trp Gly Tyr Ala 65 70 75 80 Leu Asn Pro Asn Ser Gly Ala Arg Val Val Thr Gly Thr Gln Asn Arg 85 90 95 Glu Tyr Met Glu Leu Asn Arg Leu Trp Leu His Asp Cys Met Pro Arg 100 105 110 Asn Ser Glu Ser Arg Ala Ile Ser Tyr Ala Leu Lys Leu Ile Arg Gln 115 120 125 Leu Tyr Pro Gln Val Gln Trp Val Gln Ser Phe Ala Asp Glu Arg Cys 130 135 140 Gly Cys Leu Gly Val Val Tyr Gln Ala Ser Asn Phe Asp Tyr Val Gly 145 150 155 160 Ser His Glu Ser Ile Phe Tyr Glu Leu Asp Gly Glu Trp Tyr His Glu 165 170 175 Ile Cys Arg Asn Ala Ile Lys Arg Gly Gly Gln Arg Gly Glu His Leu 180 185 190 Arg Ala Asn Ile Asp Arg Ala Ser Val His Lys Phe Arg Gln Phe Arg 195 200 205 Tyr Ile Arg Phe Leu Asn Lys Arg Ala Arg Lys Arg Leu Asn Thr Lys 210 215 220 Leu Phe Lys Val Gln Pro Tyr Pro Lys Pro Gln Thr Val Lys Thr Gly 225 230 235 240 Leu Lys Glu Ser Glu * 245 <210> 749 <211> 66 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40960..41157) <400> 749 Met Glu Gln Arg Lys Ile Thr Arg Gly Asp Leu Val Ser Met Phe Leu 1 5 10 15 Arg Ser Asn Leu Gln Gln Ala Ser Phe Asn Phe Glu Arg Ile His Gly 20 25 30 Leu Gly Phe Cys Tyr Asp Met Ile Pro Ala Ile Lys Arg Leu Tyr Pro 35 40 45 Val Lys Glu Asp Gln Val Ala Ala Leu Arg Arg His Leu Val Phe Phe 50 55 60 Ile * 65 <210> 750 <211> 266 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41168..41965) <400> 750 Met Glu Ile Ser Thr Leu Gln Ile Ile Ala Ile Phe Leu Phe Ser Cys 1 5 10 15 Ile Ala Gly Met Gly Ser Val Leu Asp Glu Phe Gln Thr His Arg Pro 20 25 30 Leu Ile Ala Cys Thr Val Ile Gly Leu Ile Leu Gly Asp Leu Lys Thr 35 40 45 Gly Ile Ile Leu Gly Gly Thr Leu Glu Leu Ile Ala Leu Gly Trp Met 50 55 60 Asn Val Gly Ala Ala Gln Ser Pro Asp Ser Ala Leu Ala Ser Ile Ile 65 70 75 80 Ser Ala Ile Leu Val Ile Val Gly Gln Gln Ser Ile Ala Thr Gly Ile 85 90 95 Ala Ile Ala Leu Pro Val Ala Ala Ala Gly Gln Val Leu Thr Val Phe 100 105 110 Ala Arg Thr Ile Thr Val Val Phe Gln His Ala Ala Asp Lys Ala Ala 115 120 125 Glu Glu Ala Arg Phe Arg Thr Leu Asp Ile Leu His Val Ser Ala Leu 130 135 140 Gly Val Gln Ala Leu Arg Val Ala Ile Pro Ala Leu Ile Val Ser Leu 145 150 155 160 Phe Val Ser Ala Asp Met Val Ser Asn Met Leu Asn Ala Ile Pro Glu 165 170 175 Phe Val Thr Arg Gly Leu Gln Ile Ala Gly Gly Phe Ile Val Val Val 180 185 190 Gly Tyr Ala Met Val Leu Arg Met Met Gly Val Lys Tyr Leu Met Pro 195 200 205 Phe Phe Phe Leu Gly Phe Leu Ala Gly Gly Tyr Leu Asp Leu Ser Leu 210 215 220 Leu Ala Phe Gly Gly Val Gly Val Ile Met Ala Leu Val Tyr Ile Gln 225 230 235 240 Leu Asn Pro Gln Trp Arg Lys Ala Glu Pro Gln Leu Leu Ala Pro Ala 245 250 255 Ser Thr Ala Leu Asp Gln Leu Asp Asp * 260 265 <210> 751 <211> 165 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42031..42525) <400> 751 Met Asn Ile Thr Leu Ala Arg Ile Asp Asp Arg Leu Ile His Gly Gln 1 5 10 15 Val Thr Thr Val Trp Ser Lys Val Ala Asn Ala Gln Arg Ile Ile Ile 20 25 30 Cys Asn Asp Glu Val Tyr Asn Asp Glu Val Arg Arg Thr Leu Leu Arg 35 40 45 Gln Ala Ala Pro Pro Gly Met Lys Val Asn Val Val Asn Ile Glu Lys 50 55 60 Ala Val Ala Val Tyr His Asn Pro Gln Tyr Gln Asp Glu Thr Val Phe 65 70 75 80 Tyr Leu Phe Thr Arg Pro Gln Asp Ala Leu Ala Met Val Arg Gln Gly 85 90 95 Val Lys Ile Gly Thr Leu Asn Ile Gly Gly Met Ala Trp Arg Pro Gly 100 105 110 Lys Lys Gln Leu Thr Lys Ala Val Ser Leu Asp Asp Asp Asp Ile Asn 115 120 125 Ala Phe His Glu Leu Asn Asn Leu Gly Val Ile Leu Asp Leu Arg Val 130 135 140 Val Ala Ser Asp Pro Ser Ile Asn Ile Ile Tyr Lys Ile Asn Glu Gln 145 150 155 160 Leu Ile Ala Asn * <210> 752 <211> 136 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42525..42932) <400> 752 Met Val Asn Ala Ile Phe Cys Ala His Gly Lys Leu Ala Cys Ala Met 1 5 10 15 Leu Glu Ser Val Gln Met Val Tyr Gly Asn Ala Asn Val Glu Ala Val 20 25 30 Glu Phe Val Pro Gly Glu Asn Ala Gly Asp Ile Val Ala Lys Leu Glu 35 40 45 Lys Leu Val Ser Ile His Asn Gln Asn Glu Trp Leu Ile Ala Val Asp 50 55 60 Leu Gln Cys Gly Ser Pro Trp Asn Ala Ala Ala Met Leu Ala Met Arg 65 70 75 80 Asn Pro Arg Leu Arg Val Ile Ser Gly Leu Ser Leu Pro Leu Ala Leu 85 90 95 Glu Leu Val Asp Asn Gln Asp Ser Met Asn Val Asp Glu Leu Cys Glu 100 105 110 His Leu Thr Gln Ile Ala Lys Gln Thr Cys Val Val Trp Lys Gln Leu 115 120 125 Ala Thr Thr Glu Glu Asp Phe * 130 135 <210> 753 <211> 269 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42942..43748) <400> 753 Met Gln Thr Trp Leu Asn Leu Gln Asp Lys Ile Ile Ile Val Thr Gly 1 5 10 15 Gly Ala Ser Gly Ile Gly Leu Ala Ile Val Glu Glu Leu Leu Ala Gln 20 25 30 Gly Ala Asn Val Gln Met Val Asp Ile His Gly Gly Asp Gly Gln Tyr 35 40 45 Glu Gly His Lys Gly Tyr Gln Phe Trp Pro Thr Asp Ile Ser Ser Ala 50 55 60 Lys Glu Val Asn His Thr Val Ala Glu Ile Ile Gln Arg Phe Gly Arg 65 70 75 80 Ile Asp Gly Leu Val Asn Asn Ala Gly Val Asn Phe Pro Arg Leu Leu 85 90 95 Val Asp Glu Lys Ala Pro Ala Gly Gln Tyr Glu Leu Asn Glu Ala Ala 100 105 110 Phe Glu Lys Met Val Asn Ile Asn Gln Lys Gly Val Phe Leu Met Ser 115 120 125 Gln Ala Val Ala Arg Gln Met Val Lys Gln His Asp Gly Val Ile Val 130 135 140 Asn Val Ser Ser Glu Ser Gly Leu Glu Gly Ser Glu Gly Gln Ser Cys 145 150 155 160 Tyr Ala Ala Thr Lys Ala Ala Leu Asn Ser Phe Thr Arg Ser Trp Ser 165 170 175 Lys Glu Leu Gly Lys His Gly Ile Arg Val Val Gly Ile Ala Pro Gly 180 185 190 Ile Leu Glu Lys Thr Gly Leu Arg Thr Pro Glu Tyr Glu Glu Ala Leu 195 200 205 Ala Trp Thr Arg Asn Ile Thr Val Glu Gln Leu Arg Glu Gly Tyr Thr 210 215 220 Lys Asn Ala Ile Pro Ile Gly Arg Ala Gly Arg Leu Ala Glu Ile Ala 225 230 235 240 Asp Phe Val Cys Tyr Leu Leu Ser Glu Arg Ala Ser Tyr Ile Thr Gly 245 250 255 Val Thr Thr Asn Ile Ala Gly Gly Lys Thr Arg Gly * 260 265 <210> 754 <211> 316 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43818..44765) <400> 754 Met Glu Asn Ser Asp Asp Ile Arg Leu Ile Val Lys Ile Ala Gln Leu 1 5 10 15 Tyr Tyr Glu Gln Asp Met Thr Gln Ala Gln Ile Ala Arg Glu Leu Gly 20 25 30 Ile Tyr Arg Thr Asn Ile Ser Arg Leu Leu Lys Arg Gly Arg Asp Gln 35 40 45 Gly Ile Val Thr Ile Ala Ile Asn Tyr Asp Tyr Asn Glu Asn Leu Trp 50 55 60 Leu Glu Gln Gln Leu Lys Gln Lys Phe Gly Leu Lys Asp Val Val Val 65 70 75 80 Val Ser Gly Asn Asp Glu Asp Glu Glu Thr Gln Leu Ala Met Met Gly 85 90 95 Leu His Gly Ala Gln Leu Leu Asp Arg Leu Leu Glu Pro Gly Asp Ile 100 105 110 Val Gly Phe Ser Trp Gly Arg Ala Val Ser Ala Leu Val Glu Asn Leu 115 120 125 Pro Gln Ala Gly Gln Ser Arg Gln Leu Ile Cys Val Pro Ile Ile Gly 130 135 140 Gly Pro Ser Gly Lys Leu Glu Ser Arg Tyr His Val Asn Thr Leu Thr 145 150 155 160 Tyr Ser Ala Ala Ala Lys Leu Lys Gly Glu Ser His Leu Ala Asp Phe 165 170 175 Pro Ala Leu Leu Asp Asn Pro Leu Ile Arg Asn Gly Ile Met Gln Ser 180 185 190 Gln His Phe Lys Thr Ile Ser Ala Tyr Trp Asp Asn Leu Asp Val Ala 195 200 205 Leu Val Gly Ile Gly Ser Pro Ala Ile Arg Asp Gly Ala Asn Trp His 210 215 220 Ala Phe Tyr Gly Gly Glu Glu Ser Asp Asp Leu Asn Ala Arg Gln Val 225 230 235 240 Ala Gly Asp Ile Cys Ser Arg Phe Phe Asp Ile His Gly Glu Met Val 245 250 255 Glu Thr Asn Met Ser Glu Lys Thr Leu Ser Ile Glu Met Asn Lys Leu 260 265 270 Lys Gln Ala Arg Tyr Ser Ile Gly Ile Ala Met Ser Glu Glu Lys Tyr 275 280 285 Ser Gly Ile Ile Gly Ala Leu Arg Gly Lys Tyr Ile Asn Cys Leu Val 290 295 300 Thr Asn Ser Ser Thr Ala Glu Leu Leu Leu Lys * 305 310 315 <210> 755 <211> 44029 <212> DNA <213> Escherichia coli O157:H7 <400> 755 tggcggagag agggggattt gaacccccgg tagagttgcc cctactccgg ttttcgagac 60 ctatgctatg ggttaataaa atcaatatat tatgtgtttt atttggaata aatattctat 120 atttaggatt gaaaaatcag atggttagca tcaaacaacc tcagaatatt ccaagcaaac 180 aggttaaaaa taaaactgca cccgaacaat tgataacgac agaaaacgcc ttttccgagc 240 caccaaaatt acttcgcatc ctatttattg ctcacgttaa cgccttgtat aactcgagct 300 ctccacggta tttaacctct cttctgttta actataattc caataaatct cgtcactgag 360 ctcaatcact tcgaaagtca agcacaatat gaatttcaca taagctatca atgaaaatcg 420 gaggtcatac cattaatcaa caataaacca agtctttctc atataatcac ttgacaaaca 480 ctcatgataa ttgtaataaa atatataagg ctataataca atactgtcaa tcaatatttc 540 atttatatga gaaaaaggca tttataatgt caattataaa aaactgctta tcattaatta 600 acaatgcatt aaatatacaa aaaacatcat attctctgac caaaatggag caggcaggga 660 agttgttaaa tagaaaaata actccagaaa atactcctcc aatgttgtta tcatacagaa 720 atgcagattt aacgcaagaa aaaaacatta cagaaagagt tttatccata tttaaaataa 780 aacgagattt tgttgctgta agaatccaaa acaatcagtt tactgatttg aaaaacaaaa 840 aaattcaagg ccatcaaaac acagttgcca gtgtcatgga ttggtataat ccccaaaaaa 900 atgctttggg tataactatg ggtacaccaa gaaaatcggc cgatatagca aaagaagagc 960 acagaaatgc actaaatttc atgataatgg aaaaaaacac atttcatgaa aaaatcttaa 1020 acagcaatga caatttgcaa aaatcataca gcaaaacaga agacagtagt tgggtcgcag 1080 cttctgtcgg ctctcttcta gataaaggag caaaagtata tcccgataca tcatgctctc 1140 tgagactggg agaaccattc atctttacgc tgccagaatc agttagagtc gatgttgaca 1200 tatatcctct caaaaaataa tcttaaaggt attgacatat aagaaataat taagtgtatt 1260 cacattagac tagtcgctta agagtagatt tttggcattt tgggaagatc agcgggacat 1320 aagagacata caacacagga ggaatggctg ttttttaata gtgctttgaa ttccgcatga 1380 aacctttctt agcagtcgaa aagcaaaaca tacgttttct ttttaacaat aattgatgag 1440 tattgcatcg agtgtcattt atacatcgcc gcatttattt gccactataa aaaggctgat 1500 tacatatcta tcggagaact aaaattactt ataaggtaat ctgcatgatt aacaatgttt 1560 cttcactttt tccaaccgtc aaccgcaata ttacagctgt atataaaaaa agcagcttct 1620 ctgtatcacc acagaaaatc acattaaatc ctgtaaaaat cagctcacct ttttcaccaa 1680 gcagtagctc catcagcgca acaactctct ttcgagcccc aaacgcccat tcggcatcat 1740 ttcatcgaca gtctactgct gaaagttcgt tacatcaaca acttcctaat gtgaggcagc 1800 gcctgataca acatcttgca gagcatggca ttaaacctgc ccggagtatg gctgaacata 1860 ttcctccggc acctaactgg cctgcgccac caccgccagt acaaaatgaa caatcaagac 1920 ctctgcctga tgtggctcag cgtctggtgc agcatcttgc agagcatggc attcaaccag 1980 cccggaatat ggctgaacat attcctccgg cacctaactg gcctgcgcca ccactgccag 2040 tacaaaatga acaatcaaga cctctgcctg atgtggctca gcgtctggtg cagcatcttg 2100 cagagcatgg cattcaacca gcccggagta tggctgaaca tattcctccg gcacctaact 2160 ggcctgcgcc accaccgcca gtacaaaatg aacaatcaag acctctgcct gatgtggctc 2220 agcgtctgat gcagcatctt gcagagcatg gcattcaacc agcccggaat atggctgaac 2280 atattcctcc ggcacctaac tggcctgcgc caacgccgcc agtacaaaat gaacaatcaa 2340 gacctttgcc tgatgtggct cagcgtctga tgcagcatct tgcagagcat ggcattcaac 2400 cagcccggaa tatggctgaa catattcctc cggcacctaa ctggcctgcg ccaacgccgc 2460 cagtacaaaa tgaacaatca agacctttgc ctgatgtggc tcagcgtctg atgcagcatc 2520 ttgcagagca tggcattaat acatctaagc gctcgtgatt ataatataat tacctatatt 2580 agctctgacc tgacagttac cggttattta tacaggtatc tgtcagatta catctaacca 2640 acaaaaaacc ggagccggac tccggttttg tgaagctgtc gggttacttc atcccgccaa 2700 tattttccca cgtcccgtca gcacgcagga tttgcagcgg tcttaccaca cactgtatct 2760 gctttttatc cgcatccagt atcaccacct gcgtgattac cctgtcctgc tccgggataa 2820 taccattctc atctgactcc aggatgtctg ccggccccag tcgcagctgt gctgtaagta 2880 actccccgtg ttcacggtca tcatgctttc cgcaaccaca cagacgctgc ataagttttt 2940 ttagtatgtt catgtcattc tcctgttctg cctgtatcac tgcccacttc atccagcccc 3000 ttaacatcct gccacggccc gtcaccaaac ctgacctgca aatgctgaaa aaaaccctga 3060 acccgtgtgg tatctttggg ggcaagaaag gtcagtccgg tgatgagcgc accatctgta 3120 cccgggaacc agccatggct gtttgtctca ataatgctcg ccggccccag acgaaaacgg 3180 atttgtgtct cccccgggtc gcccttcggt ccctgaggtc cggttgcccc caccgggcca 3240 gccgcacctg tttctccttt cggtccctgt gggcctgccg ggcctgctgc cccggtgtct 3300 ccctttggac cctgtggacc tgcatttccc gtcagaccgg tctctccccg ctctcccctg 3360 tcacctttcg gcccctgcgg gcctgccgga ccagcatcac ctgccggtcc ccgttcgccg 3420 gttgccccga cagggccggt gtcaccgcgc tctcccttat cacccttcgg cccctgagga 3480 cccgcgggac ccggttcccc ctttggcccg ggaggcccca ccaccgtggg gattcggttt 3540 acggcctctt ccgccgctat cctgctttgt tccgctgact gtgcgctttc tgctgactcc 3600 cgggcttttt ctgttgcggt cgttgcatcc ctggctgcat taccggctgc actttctgcc 3660 gtcttttttg acaactcagc atctgctgca ctttgtgatg actcactggc tttttgagcg 3720 gccgcagagg ccgaggacga ggacgcctcc tctgactgct ttgcagcggc tgcactttct 3780 gccgcctgcc gggctgactc cgatgcatcc cctgctgaag tgtcagcatt tgccgcgctc 3840 tcttctgcct gactggctga tatgccggca ttcctcgcgg acgtctccgc ctctccggca 3900 ttcttcttcg cctcctcagc gtgacgcgcc gcttcttcca ccatcagttc aaaacgacgc 3960 agtgcctccg gccggacgtc atcctccgac atggcaccga gaaaatcatt cagcgtcccc 4020 ggttgagaat cttcatacac ggtgatggtc ccggcatgtg acggcgggaa cccttccacc 4080 aacagaataa cgctgtactg accgtactca acgtccatgc tgtaacgacc ggcttcatcc 4140 ggattttcag aggccaccgt gttcaccacc accgtggcgc tgttacgtct ggctttcagt 4200 tgaatggtgc agttctctac cggttttcct gtgccgtctt tcagtacacc tgaaatcttt 4260 actgccatat tcaccccaca aaaaagcccg cctgaaccgg cgggctgtca taacactgtg 4320 ttacctggct aatcagaact tataaccgac acccacgatg aaaccgtcag tgcgccagtc 4380 gccactgccg gagccttcat aagcaatatc aatggccacg gattcggtcg ggttaaactg 4440 cacgccagcc ccccacgcca gagacgtgtt gctgtggcga ccgtcatcac ttccggtcag 4500 cacatcgtgc gttttcccct tgttgtcagt tacgcgaaga taatccccgg agaaagtcga 4560 cacacggctg taagccacac ccgccatcgc atacgcgctg aaccattcat tcacgcgcac 4620 agacggcccc gccattacgc tgaaccagcg gttacgaacg gaatcttcat gccagcgggt 4680 atcgctgtaa cgggtaagct ggcgattctt gtctcctgca tagctgaatg acgtcaccag 4740 ccccagcgtg tccgtaaatt cataacggta tttcacgtta atcccgttaa gattatcgct 4800 accgggagcg ctcgtccggg catgaagata ccccgcgctc agcgtggcct gctgctcaga 4860 cgcccatgca ggcgcgccgg atacggccag acagatggct gcggacaaaa tggcggcata 4920 aagtttacgc ataattacct ctcgcttttc tgcaataaaa aaggcgccat ttctggcgcc 4980 cgtatatggg ttataaaatt cagctgatac tgatacctgc tgtggatttt ttcatcacca 5040 caaccagcag atcgctgata ctggttgttg gtgtccagtt attcgctcct gatgaagata 5100 cggtgaatgt cagtgtcagc gtcccctgtc cggcaggcat atctataact gaggaaaata 5160 cgccctgagc atccgtcgtg gactgattaa aaatctcctg accattgcgg gtcactctta 5220 accggcaggt tgaataccag tatgactgtt ggttattact gttgaaattc tcatgcttac 5280 caccgcggaa taacactggc ggtatcatga cctgccggtc aaacttctga tcatcactga 5340 ttcttaccgt gatggtgcca ctggcataag tgctcgtgcg ggggaaagac ttgctgaccg 5400 ttttgacaat atcgccttca atctggttgg ctgacagttt ccccttaatc tgacagttct 5460 cattaatcgt gacgttgttg agcgtccctg agttcgcatt cacactgcca ctgatatccg 5520 catttttcgc cgtcagtcgc ccgtccggcg tcagggaaaa cgtcggggga ttgccggacg 5580 aggtgatact caccgcaaac agtcgcttca ggaacacgtc gttcatgaac agctgattcc 5640 cctgcgccac aaataacggc gtgctgttgc cgctctccgg atttatcatc gcgatacggt 5700 cagccagcag cagtatgttg ctcagtggct ggccatcagt atcctcaatc cctgcaccaa 5760 tcccggccac atagggaatg ccgtctttcg ttttttgaac cttcagcatg tacagcgcag 5820 ccaggtcatc atttgtgtcc ttctgcacgc gctgtatctg ctgtatagtg gcgctctggt 5880 tctccagcgt tttactgacc gtctgtgtga tttcattgcg ggtttccgtg atggtggtct 5940 tcatctccgc catctcatcc gcaagctggc tgttgtctat cagctcccat agcccctgag 6000 ccagatgcag ttttcctatt ttttcccgga aaaattccag atacccttca ccatcattgc 6060 tgggctgccc gctgacttcc acaaacgcag atttccccac caggttgacg ctgcgcacgt 6120 aaaaccagaa atccgtcccc ggcttaatcc ggcttccctg gacagtccac tgactgccgc 6180 tccccagata acgggcagat ttttccacct gtgccgtgtt cgtgatgcgt ttttccgaaa 6240 accagaactc aaactgcacc gtcgggtcat acaccgccag caccggtacc gccgttatct 6300 gaaaataccc cggcgtcagt tcaatggtgg cgggttttgc tggcgcgtta atccggaagg 6360 tggtgatggc cggttccccc tgctggccat aactgttaat tgccctgact gtcagggtgt 6420 attccccgag cggcagacca ctgaaacgat gctctgtatc cgcagtgatg gcggtggtca 6480 ccagacggct gtcctgaccg cttccactgg tcaggcgcag actgaagcgc acgcccttca 6540 ccacccgcgg cgtgtcccat ttcgcctgcg ccagatactg gctgtcagct gcactcacct 6600 ccaccgtcag gtgctgcact gccggaggga tgacgctgtt cagggtgccg ctctggtcgc 6660 cgtcaaagtg cgccccgtta tccacgatgg cttctttttc cggtacgtgc tgcactgccg 6720 tgatggcaaa ggtgccgtcc gtgttttccc ggatggagac acagcggaac aggcgacgac 6780 gcagtgacgg cagggagagc ccccacacac cgtatgtctc cacgccatcc ggcagggtgc 6840 tgacctgtat ccggtccggc gcggggtgtg cagtgatggc cacgctcacc ggcttaccgc 6900 tgccgttaat caggttcacc gtggcggcac cggtctccgg cagggtcacc tcacggtcca 6960 gtgtcagggt gcggctggcg gcatcgatgg acaggatacg tccgccggtc atggtcccgg 7020 catagtcgtt atcacagatt tcaataatgt caccgggtgt gtgacgcagc ccctgtgacc 7080 cgagcgtgaa atccaccgtc tgcgtttcca gcagtccggt ctttatcacc cacagcccgg 7140 cacggtgggc ctgaccgcga ctggtacagc cgaacgcatc catcttcagc aggttgcgtc 7200 cgtagcgcag tatggcttcc gggtcttcca ccagttccgt ggaggtctgc cagccgttct 7260 gcgggtcggt gtaattcacc tccaccgccg tgtggcggtc cttcagggcg ctgaagctgt 7320 agcgaaaccc cacgccgtta tcatccacca ccacatcact gctggtgtag gccacaccac 7380 atctgacgga cggtcctgca caaacgtcag cgtctgcccg ttccataccg gcatacagcg 7440 catcgccgag cagaaatcac tgagaacgtc ccacgcctta cgctgttgtg acaggtacgc 7500 attgaaagtc atccgcggct ctgtgccccc gaaaccatcc gggaccgtct ggtcgcagta 7560 ctgcgcaatg gcatacagcg cccacttgtc cacatccgcc gcccccaggc gttttcccat 7620 gccgtagcgc gggtgagtca gcatgtccca caggcaccag gccgggttgt tgctgtatgc 7680 cggtttcagg ctgccgtccc agatgccgct gtacgtgcgt ttttccgggt catagtttga 7740 cggtacctgg atgatgcgac cgcggatatg gtagttcacc gtcatctgct gaccgccaaa 7800 ctgctccgca tccacctgca gccccacaat cgccgtgttc gggtagcact gtttcacatc 7860 gatgatttcg gtgtatgacg accacagcgt tctgttctgc agctggtccg tggtgctgtc 7920 cgccgtctcc cggaccatcc ggatgttaaa gggacgggga ggcagattat ccagaatcac 7980 cgaagcgagg aactgtgagg tggtcttgcc gttaatggtg acatcctttt ccgtcaccca 8040 gttaccgtta cgctgcagct gaatcagcag gcggacggat gccgggttac ggtcaccctg 8100 tgaggtggtc tgcaccagtg actgcacccc gaaggtaacc cgcaggcggt caatgttcgc 8160 ggacgtaatg gtgcgcgtca ccggctttgc cttcgtcact tccacgccca gtgcggtttc 8220 agagccggat gactcaaaac cttccggcgg tgtctgctcc tgctccccgg cgcgccagac 8280 cgcggtcaca ccgtgtatca cgggattgcc gtccgtgtcc gtcagtgggg ttttgttcac 8340 cagaatactc tgcagcccct tcaccggacc ttcaatcggc ccttcaccaa tggcgtcaat 8400 cacgctcatc atctgcgtgg acttaagatt gtcctttgcc tctaccggcg tgtgcccctt 8460 gccgccccct ttacccactc tgtccccctc tcctgtctga tgtctgaatc tgtttatgcc 8520 agaaaacaac aggcaccccg gagggtgcct gtgtcatgac ggaataaaat ttctgaaact 8580 cttcacattt ccggcaattg cctgtagccg caataatgac gctgcattac ttttttgatg 8640 cctgaaaaat aactccataa cgttaatctt catcgttctc tcccgcagct ccgctaactc 8700 tgcgggattt ttttattttc atccccgccc gataaccacc actttcccgt ctccgccctc 8760 atcacgggtg ctgatgtcct gggatatccg tcgtgaacca accagcattt caccataagg 8820 caccggcatc gggttcccct gggcaatcat gttatccagt gacgaaaaat acgtgttctg 8880 tttaccgtta tccgtcgccc tgtactccgg tgtttttgcc ttcggtgcca gcatctgggc 8940 cacaccgccc agtatcatgc tggcacccag tgagaacagc atcgtggtgg cagtcagccc 9000 tccggcactc agggctgcgc cccacaacgc catcgttgcg ccggcggtga agaaagagcc 9060 cacgatggct gctgccccca gcacaatctg cagtccgccc tttccggctc cggccagtcg 9120 cggcacaata tggatgaccg ccccctcacc cagaggttcg tgaagacggg cgtacaccgc 9180 ctccggtgcc gtgtcctcac cgcgaatacg tatctggtac cagccttcgt tcatctgacg 9240 gcggaatccc ggcatctgca gcgacagggc acggatggct tccgctgccg tgttcacgta 9300 caggctgagg cggcggccaa atcgttgcaa atccccgtga aggcagatgc gtgccagtgg 9360 cggtgacgcc agacagaatg cgttcgtcgt tgccattttt cagaatacct ctcccgttta 9420 ctcagttgtt caggcagatg gtgaagcagt tcaccgttgc cgcagtatat ggcggcatga 9480 ttggccaccg atgcgccaaa gcagcacagc aggatatcgc ccgcctgtgc agaggacagg 9540 ggcacccggt aaaaaccagt cgccgccata ttgtccaggt aaaggttctg accgttgcgc 9600 caccagtcat cctcacgctc aaaatccggc agcgttatcc ccgccagatg gtatgcatcc 9660 cggaacaggg tgtaacagtc cgtcaccccg tgctcaaaac gacgcccggt caggtgcggc 9720 acacagcgga atttatgaat ttccccccgg cagaccagcc accagggcag ggcactcttt 9780 atctgcagcc gccggtcggc ctcgctcagc cagggcagac caccagggtg gctgtgaacc 9840 agcgccacaa tctccccctg catctctgcc tgcagccagt cttccggcgc aatacgaaaa 9900 tacgcctccg gctctgcgga gatattcacg cagggctggt accgttcgcc ctccggggtg 9960 cctatcacga agccgcacga ctccgcaggc gcacaccgcc gggcatgcac cagaatcgct 1002 0 gattcagtct gtgtcataaa acaggattta ctgcgaaagt ttattgatgg aaaggaaacc 1008 0 gccaaaatta gccaccatgc cgcgcatctc acacccgcgc atgcacttgc tgcatctgtc 1014 0 cttacggata tccgtggtgg ggttgtcgaa ctcatccgcc accgcaggac cgttataccc 1020 0 gcattcatct ccccggtaat cccacataca ggtattcgcc agcataatgc gaccgggaaa 1026 0 cagcgctccg tccgtctccg tcggtgttgc cagcacaaac gaggctgtca tggccgtcag 1032 0 ctctgacatc tgctccacca cccagcggtc gctcagctcc tgctccgggt ccgcttccgg 1038 0 attgcccgcc acaaaattca ccgcatccag aaaacgggca tacacccggc ggcggaccac 1044 0 cgtggccccc accaggctct gcaggtcctc cgccattccg gtgaccagac cgaacagatt 1050 0 cgacaccgtc agcgacgggc gggcactgct gcccttcccg ttcatctcaa aaccgctgcc 1056 0 gtcaatcggg tatgcctgat attcccgccc ctgccaggta accgcctccc ctttttcatt 1062 0 cagctcattg cagaaaaaat accgctcacc accctgcacc gtcaggtcga tttcccagag 1068 0 caccacccgc ggtgactgct ctgatttaac cgactcgatc aggctttccc cgtgaatatc 1074 0 ctgcatcagt tcaccacctg cttaaactcc gcgctgaact caacgcgcaa catcccgacc 1080 0 cgcgcagacc acccggcaca ggtcaccttt atctgccggt atgcataggg tggcttccac 1086 0 aaaaatgcct tccagcctcc gtgctctgcc aggaatgcct ccagatgtcg ggcctcctcc 1092 0 cgggtcacgg aaagcgtcac acggtatgtt ttcaggtcag cattcagccc cgccgccata 1098 0 cgctgcgaat acccgtcacc aaaacgcact tcacgcaccg atggctgcga gttcacctcc 1104 0 atatccggct tcactttcca gcgaaatgtt ttcatcgcct gctccccgat aacataccgc 1110 0 catcacgcaa ctgcagccgg agctcatcct gcgccccctt gcgggccatg tcatacaccg 1116 0 ccttcatcag ctgcggcccc gcctgtccgt tggtgccgtc gttctgaatc accacgtgat 1122 0 tgttctgatt aaaattaatg ccttccgtcc gccgcatctg cgccggactt ccggcaccgc 1128 0 ccacataacc cccttccgca tagccccgca tcaggcggta caggttgccg acgccaatcc 1134 0 ggctggttgc ctccttcgtg aagacaaact ccccgcgatg aacaattccc gcaggttcat 1140 0 atttaccccc cgtccccgta aatcccccgg tcgcgaaatg gaagttcgcc gccgcagcct 1146 0 gaatggccgt ccccgtggag gcagacgcac caccaccgaa agcaccgcca atggcgctgc 1152 0 cgatacgccc gacaatgccc accatggcct gtttaagcag gatttctgtc atcatggaca 1158 0 gcaccgaacg ggtgaatccc cgccagtctg cctctgcacc ggtcagcatc gccgccatat 1164 0 tctgtgcaat accgtcaaag gtctgcgtgg cagcactttt aacctgcgaa aaactgtccg 1170 0 tcgcactttc cgcccactcg ccccagccgg acttcagtcc ggccatccag cttccacgaa 1176 0 gctgctcctc cgcagaccag gtgttcttca gtgcagatgt ggccttcgcc agcgcatccg 1182 0 gattatcacc gtacacgtca cgaaggcgct gctcttccga ctcccgctgc gcctgacggt 1188 0 cggtgaggcc cgcgcctggg cactgattgc cgcctgcttc gcgccctgct gctgctcaaa 1194 0 ccgcaccgcc tgctgtgcca gctcattcag gcgtttctgg tgttcaactt tgtctcccag 1200 0 ctcagccagc tggcgtttgt actccagcgt ctcgtcttta tgcgccagca ggaatttttc 1206 0 ctgctcagat aactgccgtt tcgtggcagc ctctttcagg accgcatact gattttccgc 1212 0 tttccataaa tcgcgacgct gctggctgat tttctcattc gcaccgctgt gtttttccag 1218 0 cgtcctgagc tcggtttcaa gcgccagcag ggcagcatgc gcctggtctt cctgacgctc 1224 0 accggctgac actttgactc ctgacgactt cggctttttc agcgtcgatt cataatcctt 1230 0 tttcgccgcc gccatcagcg tgttgtaatc cgcccgcagg attttcccgt ctttcagggc 1236 0 cttattcagt tcttcctgac gggcggtata tttctccagc ggcgtcagca gacgctcata 1242 0 cgccttctgc gcctctccgg tatacttcag ctgtgatgcg tcccgttcgg cccggtccct 1248 0 ggcggccagt tcaccggctt tttccatatc cgactgcagc gtggccgctg ccagccccag 1254 0 acgggcattt tcccggtcat tccatgcgcc ctgaaggttg gcccggaaag aggcggtttt 1260 0 tccccggcgc tggctccggc tctggtacca ctgccatttt ttatccgcct catcaaatgc 1266 0 cttctgtgca ctggcgagca tatccgctga ggactcagga cgaccgatat ccagaatggc 1272 0 atcccacatc gatttgaatg ccttcccggt tttatccgcc caggtctcca gtgtccccat 1278 0 gttttctttc aggcgacggg tctgctcatc aaagcctttc gtggcgatat cgttcgccgc 1284 0 ctgtaaggcc ccggcctcat caccggaacg ctgcagctgc gcaacatacg caatctgctc 1290 0 tgccgtcacg ttacggaact ggcgcaccat cgcaatcagc cccgacgtag ggtcggtggt 1296 0 cagttttccg aaagcctctg caaccttgtc cacctccaca ccggatgcag aagcaaaacg 1302 0 cgcgacactc tggttgatgg catcaaactg ttcaccacca cgcacaccgg cattcaccag 1308 0 ggctgccagt gactctctcg cctggttaaa cgtcagccct gctgcctgcc cggctcttga 1314 0 gagcgtcagc atgcgatcgg cagtcagtcc ggactgatta ccggaaagaa ccagggtttt 1320 0 attaaacgct gaaagcgtgg aatctccctg gtaccaggcg tacaccagcg cacctgtcgc 1326 0 caccgccagc gaggtgaccc cgaccatcgg cagggtgatc gcaccggcaa gccccctgaa 1332 0 catggggatc atcccgccga aggagtcctt cacctgaccg ccctgttgca gcaggatcag 1338 0 ccagggattc tgaccaccgg caagctgcgt ggcgatatcc gtaaactgtg cgggcagggt 1344 0 tcgcatggcc gctttatact gcccgacgga aatcccggct ttttgtgcag ccagcgcctg 1350 0 gcggctcagg ccctgttcaa cagcactggc ggtttttctg acgtcggtat ccagacctga 1356 0 aaaatgacgc cttacccggc tcatctgctc atcgaaacgg acagcatcca gactcaggtc 1362 0 aataacaaga tcaccaaccg gctgggacat atctcacacc tcccggaatc cccgctgaag 1368 0 ccatcattaa tgcggcatca tccaccatga catccgccac atccgcagac gataaaatat 1374 0 cgcgccctcc gtccccaccg aaccggacgc ctccggcaag tcctgccgct ttctgcatca 1380 0 gcattttgtc ctcatccggc ctctccacct gctcttcctc atgccggggg acaagcagac 1386 0 tgaaatcaga gggatgcata tccggatcgc aaaaaaacag gctgagtaca gcgtacgtca 1392 0 gcccggaaaa atgcatatcc agctgggtat cctgaaaata atgcgtgcgg taaaaacggt 1398 0 gccagtcggc atattcggtg gatgtcatcc cggcaagcat ggcgcgccag tcgggtctcc 1404 0 ccatctcacg cgccagtctg agggcaaagt tcagctcgcc gtcgaagact ttcccgcaga 1410 0 aaaatcatca tcagtcagcg tgttattttt cgccacttca gtaatatcag tatccggacg 1416 0 aacagccccg ctcatcccgg acaggcacaa caccacgtct tccgcccggg caatggcatc 1422 0 ggcaggccag gtggtgagca cttcctgctc tatcttcatc acggcctcat tcattgacgg 1428 0 tgactgcgtt ttctgtggat ggttatgcca cagggacatc gccaccagaa acgcgccggt 1434 0 tctgacgaga tcttccacgc ttacctgcag gttgccgctg gattctgcct gttctgcacg 1440 0 ccgtttcagg agggcaagat gctcgatacg ctgcagcgca gacaattcgg aaagcgtgac 1446 0 agacacaccg ttatattcaa attgttctgt tttcagaaac atgtatgacc tccgtttacc 1452 0 ctgcagcgcc cgcttcagta acggtgactt cagccactgc ggcgaactga ccatttccgc 1458 0 tcaccacagg gatctgcacc ttacctgtcg ccacgccgtt taccgtaatt gtcatatctt 1464 0 tcacactaat ggtggctttc gacggatcgg cggaaaccgc tctgaacgtc ttgtctgttg 1470 0 cactttccgg ctcaaaagaa accgtcaggg tggttgtttt cccttttgcc accgtaccgg 1476 0 atgtcggcgt caccttaatc gcactgaccg gcgtaatttt gctgcgttct tccgctacag 1482 0 aaggtttacc cacgttagtg actttcaccg tgcgggtgat cacttctttc gccgtcacgg 1488 0 ccttaccgat actgctgacc cagccacgaa acacatccac cgtgccattc ggaaaacgga 1494 0 ttttataggc ccggacatcg ccgctttcaa accagcctat aagccctttc tggccttcct 1500 0 ctcccggttt ccaggccagc gtaaaactgg tatcacctgc agatttctgc ccctgcccgg 1506 0 tcgcggtcca gtccgcgtct tcatcatcca ggtagttatc atcgtaggat tctgccgtca 1512 0 tctcgcccgg cgtcagatcc ttcaccttag ccagtcgctg ccagtcatcg tctgacaacg 1518 0 ggtttgcata ggcgtcaccc tgaccgttat aaacccacag ggtggtaccg gctcctttta 1524 0 ccggctccag gggaattcgt gtttcggctt gacgtagccc ggacgtaaca cgcgggtttc 1530 0 accaccgcga tgacgcagca cttttccttc aacaaccggg gagacatagg ccgccaccgg 1536 0 cgtttttccg gtaattttgt ccagcatcac ctcttcggta tggaaattca ccgtacggcg 1542 0 gaaaaacagc tccagaaaca gcgcacgaaa tttcactttt tgttcggtat aaccgagtaa 1548 0 ctggcgggtc gtaaacaatc ccataaatca gttcctttca ttcagaaatc agtcaggcca 1554 0 ccgcggtggc ctgataacgt gttacggcag cgccgcgtga ctcagggcac tgccggcaaa 1560 0 ggcatttgcc tttttgtgtt catccacact ttcaggccag cggattgcct ccgtcgcaaa 1566 0 ggtccccgac ttgtaatagg tcagtaccgt ctctgtgcct tcaagcggca gtaccagtat 1572 0 gccaactgca ctaccggctt tctgtccgtc ccagaccacc agtttcccgc tggcttcatc 1578 0 cagcatcagg ggcgtcagtg ccggtgttgc cgaggaaatc ccgctgctgc ctgtggctgt 1584 0 atgagccgga tcattaccgg caaaaatacg tacttccgca cgctgttcag tgatgttttt 1590 0 cgttaccata ttgtaaaaac ctcctgttga tggtcagcac tgacttcatg gcatggccat 1596 0 gagcattttc acgtccgcat caccgtctgc tgacgtctgt ggcacgccac cctgtaccgc 1602 0 agccggtgaa tggttcgcca tgatgcgttc aaacagggcg gttgtggatg cagagaccgg 1608 0 ttctgcctta cctgatcccg cagccagcac agcccgggcg ctctccacag tcattcccgg 1614 0 gcaggcagcc agctgttcag cctgcgcctc agcccctttt gcctcatcca gtgccatgat 1620 0 ctgatcacgg agtgagggtc cggcatccgc ctgcggtgaa gcagccagga tcgggcgggc 1626 0 tttttccacc gtcatctccg gcatcgccgc cagcgttgcc gccagttgtt cacgaccgtt 1632 0 cgcttcttca cacgccataa tgcgatcggc ttcactctgc gtggatgcca ccggctgctg 1638 0 cggtgccgcc gcggccagaa tcgcccgggc ctgttcaacg ctcatgccct gttgtcctgc 1644 0 cagcatcgtg gcaagctgtt cacgtccttt cgcttcctgg catgtcagga tccccatcac 1650 0 tcgctggttc tcctgcgcgg cggcttccgt tgcagttaat tgcggcatag tgcctcctct 1656 0 gacattactg ttcagcgccg tggccatcac actgatggca tccgacgcat tgactaattc 1662 0 atccgccagc ccggcatcaa tgccggactg accttcaaaa acggcggcct ctgttcccgt 1668 0 gacggcatca acagacagac cggtaaacat ggccactttt tcggcaaaca tccggcgcgc 1674 0 cgcatcaatg cgctgctgca tgttctggcg aacctctgcc ggtaaggctt caaactgatt 1680 0 gccatccacc ttgtgcgccc ctgagtaaat cagcgtgata tccacaccgg cctgcgccag 1686 0 atgaccggca tagctgacat ggctcatcat cacgccaatg gagccgatac gggatgtctg 1692 0 ggtaaccagc cgtcgggagc aggccgacgc cagcagcatg gctgcagaac aggccgtgtc 1698 0 attgcacagt gcccagaccg gcttctgctg acggaggcgg taaatcatgt cagcgcagtc 1704 0 aaacgcgccg gcggcctgcc cgcccggact gtcaatgtcc agcagtacgc cccgcacctg 1710 0 gctatccgcc attgcctgct gaagacaggc gacaatgccg tcatagcctg tcattccgga 1716 0 aaatggccgc atacccccca gccggtgcac cagcgtgccg gtcaccggca gtacagcaat 1722 0 accgttcacc acccggtaaa cacgggccgg tcgtttacct ccggccatgt actcgtccgt 1728 0 ttcagccagc attccgggag catcaagctg tacctgctgc tgtggtaccg aaagacttgc 1734 0 tgcccccatc tcgcgcccga gcgcgcaaaa gaaaacccgc gcataggcgg gctccagaag 1740 0 cagcggttca ttgaatgctg cggcaataat gtgtgaaaga ttacgtctca cggggtgttg 1746 0 tctcctcttc cggcctgcga ctctccgcta tctgctgctg atacgcctgc gctatccaca 1752 0 ccggacgtga gagtccggct ttttgccgct ctgcagattc cctgacctgc tggcggaaaa 1758 0 tgtcctgata atcctcgccc atcagcgccg gctctttctc atacgtgctc agtccggcct 1764 0 caatgcgcat caccgattcc tgaacctcct tgagcccgtc aatggccatt cttccggcac 1770 0 caatccactc tgcccgtgac caggctgatc gcgcctgata aaaatcaaaa cgcgcccgtg 1776 0 gcggacggat aatcccccga agaagtgcct cttccagcca gtaggaaaac atctgcgtgg 1782 0 ccagccgggc cgcaataaat tttcgccgcc ccataaaata gcgccacgac tcattggcag 1788 0 aggccctggc acttgaataa ctgaccttcg agtaatcacg ggacaactgt tcgtaggaaa 1794 0 cgccaagacc ggcggcgata taccgcagca gcgcctgttc aagcgccgaa aatccattgt 1800 0 ctgaatcctg cgcagtctgt agtttcagat catccccggg gaaaaggtgc ggaattttga 1806 0 caccacccag cgtcacgtta ttcgtgtcat accagctgga gaacttctcc agaatattaa 1812 0 taagcggatt atccttctgc ccctgcggcg caccggcgat atattcaaag gccttttcgg 1818 0 tatcaaggtc actttcaatc gtcgctgcat acatggcttt cacaatggcc gactgaagct 1824 0 gtgttgcctg cagggaatcg agcatcttca gccgttccat gacgctgtaa aactggttgg 1830 0 ccccacgggt ctgcccgtcc tccaccggct cgaaaatatg cagcatggcc ggacgcccgg 1836 0 tgggaagttc acgcgggatc cgttcccatc gtccactccc ggagcgagga aaatcatcct 1842 0 cacagatatg gtacgcaacg gcacggccat atcgatcgac ctccaccccg gcccgcagaa 1848 0 aacggttccc cataccgtgt cctggcgtgt ccacccgttt cggactcacg gctttaaaac 1854 0 gcgtacggaa taactgcgtg gtttccgtat cccagaccgg ctgcacaaag atttcgccgt 1860 0 taaacgcatg aacgcccaca ccttcacgga taaattccgt gaacgtgcgt tttccttcca 1866 0 cgtcgatctc gccagacatc ccttcggcgt attccgacca ggccgcctcc acctcatcga 1872 0 caaagctttt tgctgcggtc tcccgcatcc ccagccagcg ccagttcgga cggtagctga 1878 0 taagaaacat atgcccgaca atgtgatcct tatgcagtgc caccgcattg gccgctattc 1884 0 cgttattgcg caccagatca tctgcccggg cattccccag acgcaacgcg ggcagcaggg 1890 0 ccgcatcggc actctgcgcc ggtggcaacc actccgccat ttgcccgcca aatcctgcac 1896 0 cgcccccgtt gtagctgaga ctctcacgaa gcggaacgcc gttcacatca atcaggacag 1902 0 gcgttcgttt cataacctca ctcccagcgg acgacggcga cgccgggttg tccccagtac 1908 0 cgactccgca tcattgatcg cccggttaag ctcatccaga gaagccgccg tatattcaat 1914 0 tctgcgacca tctttctgga cagacaccac ccgtttaccg gttaataaat caaggcgcgc 1920 0 ctgacgcagc gcctgcagtt cagcgactgt aaccattcac tcctccggac agcttcgctg 1926 0 ccagttcttt cagggttggc cgggtcgtct cttcttcccg ggattttgcc agtacagcca 1932 0 gatcaagctg ccagcgttgc acggacacac gtaatgccgc gtaggcatac accaggcagt 1938 0 ccagcgcttc gttacgccgc tttttgttat cccacagcag acgcatcttt cctttttccc 1944 0 acttctccac cagctcttcc gccaccagtt gctgcgcctc tgtctgcgaa aaaatctccg 1950 0 gatcatcagg aaaacggatg gcatacgacg tggcttcatc cgcaggcgag ggatcggctt 1956 0 tcatacgggc atagagaatt tcttttgcgg tgtccgttcc cacttcacac agatacacgc 1962 0 cccgctgatt gcgggttttt ggcatggtga tcaccggctt gccatagaca gatgcgcctt 1968 0 ttaccggcag cacccggaaa acaccgtgtt tttttgatct ctgataaaca atttcaccat 1974 0 cgatcccccc ggtgtcccag cagacacggg aaatagtcat ttcggtgcca tccgcatggc 1980 0 ggtatttttt gttgatcgcc gcatccacac gtaacagcgt ctcttcctca tcaggacgcc 1986 0 ccataatgat gattttatcc accagaaagg cttcctctcc cggagcccat ccccagacat 1992 0 acatctcaaa acggtttcgc tgcgagtcaa tgcccgccgt cagataaacc acccgggcag 1998 0 gcaccgccgc cgtgtaacgc accaccttat ccatcagtac ctggtgatcg agtttttcgc 2004 0 ccacggcctc ttcccaggtc tcgcccagcg tggtgttcac aaaggttttc aggccgttgg 2010 0 gatctttcag tgcatccagc cagtcataga caatctgtac ccaggtggtg aacggactgt 2016 0 acgccgtcca gatatggaac atgatggagc gcggcggcgg aatttcatca ccccgggcgc 2022 0 tgaaaaacgt cagaccgtca cgggtccaca tgcccgtgtt ttcacagatc caccgcccgt 2028 0 tgctctggtc cagttcagac tgatggatca cgcagccatg atgttcacag aggtagaaaa 2034 0 cactttcagg gctgtccttc tcccatttaa gcccaaaagg cgtggactca tcgccaaatt 2040 0 tcagatactg cgcctcccca cagtgcgggc agggcacata aaaacgcata aaatgcgccg 2046 0 actcgttagc ggctttttcg atctggcagg tgcctttgat tttaggcgtc gagccgcgaa 2052 0 tggattttgg ccacaccgac ccctcaatac gcttatcccc cagcagggtt ggcgagccct 2058 0 ctttttcgac atccggctcg aacgaggaaa gttcgtcata gcagaccacg tcaacggatt 2064 0 tttcacggta gtttttggcg gcagcgccgc ccaggcacca gaaaccgacg cccgatgaaa 2070 0 agcgtttcag cgtgagagta ttgtcacgat gtttacgacc cagccatggg gaaaggtctt 2076 0 tcaggcatgg cacgttccga atcgtcgcct ccacgtgaga cttcataaaa tcttcagcgg 2082 0 cagaatccgt gggctgaaaa agcagactgt ttcgggattt atgctcaata aaatacccgc 2088 0 ccccccccag caacatcttt gtatagccaa cacgggcaga tttaatcaga ttaacagtgc 2094 0 ggatctgatc attccccata ctgttcatga tggcgatctg gaatggcagc gttttccatt 2100 0 cgccctcacc atatgaagat tctttaggca gataataatt ttgatcagcc cattcaactg 2106 0 gcgtcaccgg caatgccctt atcaggggct gtaatgcagt tgtgacagcg ctcatcatat 2112 0 tattcagttg ttgctctgat atattcatca agtaaatccg gtaatttatc ccctgcccgc 2118 0 gcacactgat ttgccccctt agcaataagg gttttcagat ggtcaagatg gcgcggtgtt 2124 0 aaatcaggaa actgtcgctg catggataaa gggatggaat caagcgtact ggataacgcc 2130 0 attgccagct tactgagggc aaaaatacag aacccggtgt caatcagttt tccttttgac 2136 0 acctcatttt ttaactgctg tgtaacagcc tgttctgctg tcagttccca tctggcaata 2142 0 agcaatttct cctcatagtc gtcttcgcta tcgccatcag gcacatcgtt tttacttctc 2148 0 ctcagatacg atatgtaaaa atcgcgccag gcatccagat ccagttgccc tcgcttattc 2154 0 gatatcgggg cacccggcaa tttctgcaat ctgcgaagct ggcgatcggt cagacttaaa 2160 0 tgcctggcaa cttcagtctg cgtagccact cctcacctcg caaaaactct cacctcacaa 2166 0 tcacaacaaa accggtcatg tccggtttac atgtctgttt tttgttcatg tccggttcac 2172 0 agaagacctg tttttatatt tttcatatag ttaacttgaa gagaaaccgg acatggatcc 2178 0 cggaaaattt tcataaatag cgaaaacccg cgaggtcgcc gccccgtaac ctgtcggatc 2184 0 gccggaaagg acccgcaaaa tgataataat tatcatctac atgtcacaac gtgcatctac 2190 0 gccatcaaac cacgtcaaat aattaattat gacgcaggta tcgtattaat tgatctgcat 2196 0 caacttaacg taaaaacaac ttcagacaat acaaatcagc gacactgaat acggggcaac 2202 0 ctcatgtcaa cgaagaacag aacccgcaga acaacaaccc gcaacatccg ctttcctaac 2208 0 caaatgattg aacaaattaa catcgctctt gatcagaaag gttcaggtaa tttttcagcg 2214 0 tgggttattg aagcctgcag aagaagatta attaatgaaa aacatgctca atttgtaccc 2220 0 aacaaagaca aacacgacca gagcacctgt tcagacaggt ttacttaaac gacttatata 2226 0 tgacacaaaa agcgaccact aaagtcgctt tttcttatgg taacaggcaa taacgctctc 2232 0 agatattttt tagcattttt ttgaccgcgc gtttccggac gtattctgtt ctcctgtccc 2238 0 tttatatcgt cggaataccc gccgctcttc aaatcccatt cccaactcag aatgtagtct 2244 0 gttgaccgct tgttttattt ctgtcaggtt catcggtgaa accggagtcc ggcgcgcctt 2250 0 acgcaaacac tctgctcgtt tctgtgccgc cacttttctt ttctggtcat cacttagctg 2256 0 taccatcact tttgcccatc gttcagctgc tctccggtac agtccttttt tctccagaca 2262 0 ttctgccagg tgatcatgta gcataagtga cctccgatta tctacagact gctatcctga 2268 0 atttaccttc ctttaatgaa ataacaataa aaaataaatc acagaaaaac aacaaaacaa 2274 0 cacacaaaaa aaccaaataa taaacccaaa taatcacctt attttattat tttttgagag 2280 0 agctattact gaacaaaaaa cgctgactat atactcaaaa ccaaacaact attctgccaa 2286 0 tcaggtataa tggcaacaca aggaattacc gtgtttttgc cttctctgcc catacaatac 2292 0 ggacatatac ttcatactct attgtaatat ttccatccat gcgaacaact tcatttatct 2298 0 gtaaataata ttcaaaatat ttatcacaga aatcgttttt ggccatgaac tgagcacact 2304 0 ataaagtccg gaactgactc tttgttaaat taccttaacg ttaccagtaa caccttcata 2310 0 acaaaacatc acggtataca ctgggtacgg atatattcct gtgctccttc cagttgcttc 2316 0 tgcattgcca tcagccgttc tctgaggatg aaataatccc gttcagcggc ttctgccagt 2322 0 cggggaccgg ttgcattatc cacgccggag gtgatggggg ctttacgcaa ggagcctgga 2328 0 cagttggcgt tgatgcgcag gcgcttacga ccagcggcaa catcagcacg cagagtttca 2334 0 ttttcagctc tcgcatcggc taattccctc gagtatctgg catcaagtgc agcgacatca 2340 0 cgctggcgta cctgcatatc agtaattgtc acgttcgcca gcttcagctc actggctttt 2346 0 ttatcgcgtt gcgctttgta ggtaatggcg ttatcgcggt aatgattcag ccccagacta 2352 0 agcacaccac aggctaccag caggacaata atcaccacac acagaacacg gttcatatcc 2358 0 ccctcacccc accagccatg acaaagttaa gacgcgccag gcagtggaaa agcaaatagc 2364 0 aaccagcatt agtgaaaatg aaatgccgac gattacacag aggatcttcg ccagcgttat 2370 0 gagcttgtct gacatgctta atcctcttca cgatttcaac gcaatgacca gttttgccag 2376 0 cccatacagc atcggagaca cagcaatacc gaccgccacc cacttaatag caaaagccag 2382 0 cgctctgctg acgtcatcag ttacaggcgc tttcagttca aggccgtttt tcatagtcaa 2388 0 tctcaacaga attcgtttat actttcccat gttctccctt gccttactca aggtcagaaa 2394 0 cacaaaaccc cgtttgcggc caacaaacgg ggttttactt ttattcactt agtttttgcc 2400 0 agttcgcagg atttcgtgtt atccgccagt gtgagcaaac cgcatttttc agcaaaatat 2406 0 tctgcttatc tgtcaattcc ccagcacgcc agcgcgctct cctggtcacg ccgtgaaacc 2412 0 tgaccgtagc agttgtttga gcgaatacgg cagtctctgc caccgtcctt aatccaccag 2418 0 cgaatcgcct cacacgctcc cctgcgatca cctgcattaa ttcgtctgta aaacgtcgac 2424 0 gggaaacact taccgggacc aatgttgtac ggacagaatg acgcgatccc cgctttctgg 2430 0 ggttcggtca gcggtacttt aatattgcgc tccacccact ccagcgcctt atcacgttca 2436 0 atggcgttaa cctggtcgca tttttccttc gacaacttca tgcccggaac gacaggttta 2442 0 ccatccacca ggatggcacc gcggcagatg gtccagatac ccgcaccatc acggtatgcc 2448 0 gtggtgtggt taccttcttt ttcgtcaaga aactggtcga ggatttcagg cgcagacgcc 2454 0 cctgcaccaa tcagcgccag aacggcagcc gacaggccgt atctgatttt tgcgttcatg 2460 0 gatatttatc agggtttatc gatttcaaat ccctggatat gttaagtctt caggccagcg 2466 0 gtggagtctt cagagaaccc gtaattattc ccggtagttt tcctctgtag gttatcaaca 2472 0 catcctgcgc ctctaaaatt acggggcgct tttccggcaa cggaccatcc ccttcacata 2478 0 acccggcagc aacatccatg aaaaactgct tcgcctgctt tttcgcctca gcttcgtaaa 2484 0 actccagcgt ggcaccttca gtacggtcaa gactaatcgc cacatctggc aacaacagtg 2490 0 acggataccc accaatttcc ggtgccacag taacagtaat cttatccggg taattattta 2496 0 tccctttaac acccagttcg tattttttct tcatcgcttt actccccccg cgccgcctta 2502 0 cgacggtcct ctctgatttt gaaatacagg ttagtcagat acgtcagcag gccaaacagc 2508 0 agactcccca gcacaccgat tgccacccac tgggacggag agactttgtc cagcagctgc 2514 0 agtaaccagt atcccgtccc caccgctgac gtggtgtatg acacacctgt tgtgattttt 2520 0 tccatctgat gtatgtctcc gtcaccgccg acagaaaatg aaagtaaagg aaaacaaaaa 2526 0 gccgccagtg tcgcccactg acggccaacg ccgggagccg tgattatggc attcaggctc 2532 0 tgctaaaaat gccagataac attccggctc ccccccctga ttcaggttat aaatgacaca 2538 0 atatcttgac aacacccatc actgtctgtc agaaaatgta ctgccagata taagtatcat 2544 0 gtgaaaccca actatccttc ttagccagta tgaaccgccc cggaaatcct ggagactaaa 2550 0 ctccctgaga aagaggtaaa caggatgact aaaaatactc gtttttcccc cgaagtccgt 2556 0 cagcgggcga ttcgtatggt tctggaaagt caggatgaat atgactcaca gtgggcggca 2562 0 atttgttcca ttgccccaaa gattggctgt acgccggaga ctctgcgtgt ctgggttcgc 2568 0 cagcatgagc gggataccgg gggcggtgat ggtgggctca ccagcgctga acgtcagcgt 2574 0 ctgaaagagc tggaacgtga aaatcgtgaa ctgcgccgca gtaacgatat ccttcgccag 2580 0 gcttccgctt attttgcgaa ggcggagttc gaccgcctct ggaaaaaatg atgccactgc 2586 0 tggataagct gcgtgagcag tacggggtcg gaccggtatg cagcgaactg catattgccc 2592 0 cgtcaacgta ttaccattgt cagcaacagc gacatcatcc ggataaacgc agtgcccgtg 2598 0 cgcagcacga cgactggctg aagagagaga tacagcgcgt atacgatgaa aatcatcagg 2604 0 tgtacggtgt gcgtaaagtc tggcgtcagt tgttacggga aggaatcagg gtggccagat 2610 0 gtacagtggc acgtctcatg gcggttatgg gacttgccgg tgttctccgg ggtaaaaagg 2616 0 tccgtacgac catcagccgg aaagccgttg ccgcaggcga ccgcgtaaac cgtcagttcg 2622 0 tggcagaacg acctgaccag ctgtgggtgg ctgattttac ttacgtcagc acatggcagg 2628 0 gcttcgtcta tgtggcgttt atcattgatg tgtttgccgg atacatcgtg gggtggcggg 2634 0 tctcatcgtc tatggaaacg acattcgtgc tggatgcgct ggagcaggcg ttgtgggccc 2640 0 gtcgtccgtc tggcaccatc catcacagcg ataaaggctc tcagtatgtg tcactggcct 2646 0 atacggagcg actaaaagaa gccggattac tggcatcaac agggagtaca ggcgactcgt 2652 0 atgacaacgc gatggctgag agcatcaatg gtctttacaa agcggaggta atacaccgta 2658 0 agagctggaa aaaccgtgca gaagtggaac tggccacact aacgtgggtg gactggtata 2664 0 acaatcgacg attgctggga aggctgggcc atactcctcc ggcagaagca gaaaaagctt 2670 0 attatgcttc catcggaaac gatgatctgg cagcctgagt tcacagataa aacactctcc 2676 0 aggaaacccg gggcggttca gtacttctcc gacgaaagtc agtactggct gtttttttat 2682 0 tatgctgccg gtgcatttat ctccagcatc agactttcta tctcaacgcc atacgctgca 2688 0 ttttttgtaa catccgtcag cgtcagcgca ttcagtccca gtgtcagact gtcttttata 2694 0 acctggaatg ccgggccagc cactccattc agtttcggag taaccatggc actgccggcg 2700 0 gtgaacacca gctccagcgt ctgccagtcg ttaccgtaat cgccgaactc ccccagcttc 2706 0 gtgtttccgg ctttcctgtg atgcatcaga ttcaccctgc cgtcagtggt ctgagtgaag 2712 0 tacgacatca ggaacggatt accggtaccc gtcatcgcca caccatcagg aacgggagca 2718 0 tccgtataca gataaatccc cagcccgaac tgattgttgg tcagtgcgcc tgacaggcgg 2724 0 aacttacagg tcagtctgcc gccctgtgtc agcagggtaa ttgcgtcatc caccggatgc 2730 0 gtcagggacc aggttttatt gctctgcctg gtgatcttaa atacaccatc tgacaactga 2736 0 attccgccat ccttaatgct ccagccctgc gcagcagcct ctccggctgc cggcagcagg 2742 0 gagattgtgc gaacggacgt atctgcagac ggacccgatg gcgtgttgcc gccgggcgag 2748 0 ggtttgattt ccggtgcctt accactgatg aaggctgagg tgcgcccggc tgcgttcaga 2754 0 atagcggttg ccagacgatc cggaataatg ctcctgcgcg cccatgaact gaaatgtgtc 2760 0 gggcggtttg atgatacctg gtttccattc gttctcgatg ccgcaccgta atatcctgat 2766 0 gccggaatat ccggatcttc tgccggcgcg ttagtggcgg tattgacgcc gttaccgtct 2772 0 gtcatgaagg gcacaaaata aacgccctca ctctccctgt ttttataccc gccgtacacg 2778 0 gtgtcgtact gggtagcgta tgtatttttc cagtaatacg tcgtgtcacc acaaatccac 2784 0 ggcacatctg cagcgctgcc accatggcac tgcgcgttaa acacggagag gtcagcacga 2790 0 aactgtgtca gcatggctgt aaacagcgca ggttgctgtg cgtgggtggc ggcgctcatg 2796 0 tcaaactcac cctgcatcca gcagacggcc agcagaacgt ttttgggatt tttctgcaat 2802 0 gccgcttttg tgcgggaaat cagatcctga tataacggct tgcccacccc ccagcgtgcc 2808 0 gaatcctgac tggcccccgt ggactcgctg aatgtcccct ccgcgccctg ggtaaatgcc 2814 0 gaaccaccac gacagcatgg taccagcagg atccccgcgt tattcgggat atacgggagc 2820 0 agttttttgg caatatgtaa accctggccg acacagccgt actgcccttt gctcaggtca 2826 0 gccctcggat gattcagcgt actcatatcc tgcacatcat gcagacagtg gtcagccgga 2832 0 ataatatcgt tatatctgca ggcagccccg cccggcgtca ctgtactgcg gcgcgccagc 2838 0 tgtttaatgc gcggatccgg agcatcgtat gaatccggca gcggaagccc ttcaccgtaa 2844 0 gccatggcat tggactgccc ggccagtacg atgacgtagt accaatccgg ctcagatgaa 2850 0 gggccgacct gtggctctcc ttcaatagcc accgcctgca tcagtgtgta cggcgtaatg 2856 0 gcaaccggtc cgccgtatgg ctgccagccc tctttcagtt tgtgtgtcag cttttccgca 2862 0 aggtctgacg gcgacgccgc cctgacaaca tcataatgtt taatcgacat cgaatttctc 2868 0 ccgtgtagag gaacagagtt aaaaagccgg aagcggaatc aaatcacagg atgaccatct 2874 0 gccagtggct ggtcgtaaaa aaaggccgcg ccatgcgcag ccgaaaataa agggataacg 2880 0 atgatagttt gagaaaaaca gaaataacac ttttgtggca aagcatggtg ccgggtgcct 2886 0 cccggtgaat tcagtatcag cacctgaatc cgcgattacc ccatattcct tcttgctgat 2892 0 tgccccaccg cacaggggga ttcaccatgc agaagtgttt ttaataaaca gcaaacaaaa 2898 0 aaatcaagca ttatgcaggc tgtttctttt tatcaccggc cacagcaata ccataatgcc 2904 0 gcagaccagc accccatccg ccagcaccga catgattctg ctggtgaaat ccaccatcac 2910 0 caccagaaac agcaggagtg cagccacagt caggcgcagt tttaccgtca caggtaattc 2916 0 tccagacgaa gacccagaac accggcaatc tcttccagca ccttgcgctc ttccggctca 2922 0 atttcgccgt ctgcctccgc aatggccacc gccacatcca gcacatcttc cgcttcacgc 2928 0 gtatcgtgtt tcacatcctc gatctcacgt aacgccgcac gacgaccagt tttaaagttc 2934 0 gtatccagct gaccgataat ggttgcgcta atcgcattaa tttctgacgt aaacgcgtac 2940 0 agcgcaggct gattacgcag tacctgttcg atcttcgctt tctcggatgc ctcacattca 2946 0 ccatctgcac aggccaccag gtatgcggcg ttaatcacca cctgtgccag atcgcgtttt 2952 0 tcaaactttt taatttccgt tgccgctctg cgggcttttt ttaccaaaaa taccaaacat 2958 0 cgtgacgttc ctttgggtgg gtgagccaac gcccgggagc gatctgccca cagagaaagt 2964 0 cacactgacc actccataag ctccccccga aaggctctgt ggttggtatg cgccgggcgt 2970 0 ggtgcggata caaaaaaggt ccgcaaaagc gagcgaggga aaataagtgt ggtgcgttgt 2976 0 actgggttcg aaccagtgac cgattgctta gaaggcaatt gctctgtccg gctgagctaa 2982 0 aaacgcagaa taccgataat ggaccgccat cggagactcg aaccccgcga aaccagcttc 2988 0 gaaggctggc gttctatccc gatgagctaa tggcggtatg tgatggtggc ccttgctgga 2994 0 tttgaaccag cggcctggcg attatgagtc gctcgctctc accactgagc taaagggccg 3000 0 ggcgcaggat aataacgtta cgaaatcaat gttgcaagca ttcaagaatc acctggttaa 3006 0 aaattaccct tgcttcctcc accagcgcat tcaccatgtc tatccgagat aagtggcaca 3012 0 aaaaaacccg cttgtgggcg ggttttgttt gcttttgcca tcacgtacaa aatcggcaaa 3018 0 atatcagatt tgcatgaaat atatgccttt caatctactt ttgcaacact ttgctttgaa 3024 0 aatgccgcct tttgttttga acgcgttctc attacaaaca ataaagcctc actatccagt 3030 0 cggtgaaaaa tgtgtttcat tgcaacccag tgacgagtaa atgttttgga ccagttttta 3036 0 gttgtcactc ccaccagtaa tgccagctcc ttgtattcat aaccttcccc accaaaaagt 3042 0 tctgctttta ctgcctgcgc cgccagccag attaattttt tcaggcgttc ctgcgttttc 3048 0 cctgcaattt ttctggtacc ggattgagta ttaaattcat tccacgccca ctgtgttatc 3054 0 gcgatctgat attcccaaca aatactcccg ctgtaacacc acaacaacca ggctttatga 3060 0 tgttcttcaa gagacagaac agcccgccgc cacgatgatg tcgaaaactc aaccggactg 3066 0 accagaggaa ttgacgtcac cttcgccagc gattgctttc ccgggattgg tggattatcc 3072 0 cgcgttatca tttttccagt cacttcatcg cggtaccgga ttttttttcg cctgtaacgc 3078 0 cctgtatcga acatggcatt ctcctgccag gcttcaagct gaccttttgt tgccccactc 3084 0 aaatcggcgg tagcgataat gagcagctca cgcacaaact gtaaatagtg gttattcatg 3090 0 cgcactccag ttctgtgatt tttatcccca gccgctcacc aggaacgagc tgaccgcgca 3096 0 caatattgat ttcatcaaac tgctcatcgt ccattagcaa ccccgcatgc gtcagcgcat 3102 0 ccagcggcgc tttcagaata ttgtccaggt cacggcggcg cttatccggt ggctcggcaa 3108 0 taatctttat cgccagcctt ccggacaggc ttaatttcag ccgctgctgg cgaacaataa 3114 0 gcgccacagc ccggcgataa cgctcaccgg cttttgatac aaaatatgtg ctgccacgac 3120 0 gtcgccagta ggtgttcacc gtcggcgggt aaggtaaaac caaatctatg agcatcagtc 3126 0 acctctttta cccgagcacg ccagtcgcaa aggcgtgatc aagaaaacga aaaattaact 3132 0 caatctgaga gccgtacttt ttctcaaact ccagcgggtc tgcatgaagt tcgttgtggt 3138 0 gctcccggca caacggtagc gtgaaaatat cgtgggcctt tgtccccatt cccccctgac 3144 0 catgaccaat caggtgatgc ggatcgtcag caggcttacc acaacacgca cacggctgtg 3150 0 tctttaccca gcgcgtgtat ttctcattaa cccagcggca acgtttaggc cgcctcatga 3156 0 acgattcagg agactccgga tcaacggcga tactgacaac cgtttttttc tgtggtggat 3162 0 tttgttgctg gtggacgtga agtggcagcg caatattttt tgtgcgctgc ttcagtatgc 3168 0 tgatggctgt ctgttctccc ggtacgatgt cactctcacg gtatacggag cggatttttt 3174 0 ccgctggtaa tcccagcgaa cgacgcgcta ctgcctcagg tagtgcatcc accacctgat 3180 0 tgcaggccgc ccaccaggat aattcagcca gcgataattc acgctcctgt gtgccattca 3186 0 ttgcgtgacg aatgacgtca atcatccatg ctgacaggtt ttggtgagca agttgctcaa 3192 0 gtgattcgga ggtctggtca cgcaactggt tgtcgcagtg ccagcacaac accattgcgc 3198 0 cggtaccata acggtgaatg acggtttcac tgtggtgata atcgccgtgt ggccactggc 3204 0 aggatttaac atggcgcagt aaccagtcag acagtgcgcc agcgccacca gcagcacgaa 3210 0 tcactcgttc gtcgctgaaa aatggcagta atgatttatc ctccgccagc ggctggcgaa 3216 0 cggcaggaac gaccccggac ggcagattac gcatgctttt cggttccggc tccaccagta 3222 0 cccgggtatt gtggaatacc ggcatggatt cacggcccgg cttaacgatc accagcccga 3228 0 gttccggtac cagaacaggt cgaagtaata cccgcacgtt acctccagat gcgttgctgg 3234 0 aatgtgcggg acggacgcgg tgggcgttcg gagtaaggaa gcctgacgga gattatccag 3240 0 tgacgataat cgagactgag ggctttctta acctcgtatc cgcgcctgcg gtaacactga 3246 0 atcagccatt cagcctgttc ttcggtgcag gggtcgtgct gataccagtc agatttgaat 3252 0 gcatgagaac gccgcccgtg cctgctggca ggggcggcag agttatccga attgtaaaat 3258 0 ttggtatcgt gcgccatctg ttttctctgc tggcgcagca ggtgccagtt gttcaggctg 3264 0 acggatggat tgtaaaccag aacgaccaga aaaaacaaaa cccgccgaag cgggttaagt 3270 0 gcgggtgcgt tgaggatgcc tgacacatca gcggtggcga gggatttctc ccccgcctgg 3276 0 tctcttactc ctcaggttcg taagctgtga agacagcgac ctccgtctgg ccggttcgga 3282 0 ttcgtacctc gcagaggtct ttcctcgtta ccagtgccgt cactatgacg gttaaacaga 3288 0 tgacgatcag ggcgattaac atcgcctttt gctgcttcat aacctgcttc tccttgcctt 3294 0 tcggcgcgta agaggctaac ctacgtttgt gaagcataga ttgggcctca gattaatgtt 3300 0 aagcgtcttg caggacgcgt aatgttaact ggggcttttc tctgtctgcc ttacggtggc 3306 0 atgcccgagg cagacagcct caagcacccg cagcaattct acttaactct cgctttacag 3312 0 caaaccgttt tgcccgatat gggaattccc atacggaatg aattcagttc cccaggcgct 3318 0 ccatcaaaaa cacaaccagg cagtaaacac ccacaacagc aataacagcc agagcgcctt 3324 0 ccattaccag tgaaatatca tccgacatat tccctccctt ggtgtgaatc ccggcgaacg 3330 0 tttttacccc caccgacaaa taacatatac tagaaaagca atagctatag caacgcctgc 3336 0 aaatgcatct ggccggctca ttggttctcc ccctgtgtcg cttctactgc gatctgactg 3342 0 gcgtattcgt taatggtaac gataagttct tgctcggcct catccagaca actaccgata 3348 0 cctcgcctgt ccacttcaga agcatcgaaa tctgcacgaa gcctggcgac cttcaggatt 3354 0 gcggacaaca cctcatcagg gattgccgga gagttggttg acgtttccga gattatccga 3360 0 aaattattgg ttgacgaacc cttattttcc cgaaagtttc cagcctgaag catggcggcg 3366 0 cggtgacacc agataatcca gccaagcgcc atatcccatg ccatgtattc tctatcgcca 3372 0 ttttttgctc tgcggcgatc tacagattcc ccgaaacgct tctccataaa taattcatag 3378 0 gctgcccgtt catccgatac tgatgccagt gatgccagtg caatttttaa tgcggtaagc 3384 0 atgttgtttt gatcttcatc gagtccgaac ggtatttcat cccgtgatga ctcaattccg 3390 0 gtaatcgtgt tctgtagcca ttctttggtt aattcagtca tttttcacta ccgccctttc 3396 0 gggcggtctc ctgatgttct gagggtgcag gaatccctcc ggttaaggat ttaataaaaa 3402 0 tcatttctga tttaaatttt cagtgtttag ttgttggttt atagccttta tgcttcggcc 3408 0 ttatttctca gccatacaca aacaggacca tcttcggtgt catgtatcga accgataaac 3414 0 catccctcac cttctggtcg ctcaggttcc catgctgaaa tatcagggcc atctgcgtcc 3420 0 agattaaaat catcttcatc catactacgg atagcccact gaagattatt tttctccatc 3426 0 caggcgttaa actcttccgt tgaaatatat tcccgaccat cacagaattt ttcatattca 3432 0 ggatgcgtcc agcagccata ttcattacgt tccactggca tttctttaat tacgctcatt 3438 0 tacccccctt atttaatttt ctacgacact ttttacaatc atctggactt tcgaatgtat 3444 0 ccggctcacg ctcattgcca aaatacatcc acccaccgca aatacttgtt atttcacctt 3450 0 cagcaaaata atgatgtttt ttcgccataa gtggccttgc ccagcccgga ttcgttttac 3456 0 tcacttgttg cctcctttgc gaagctctgc gactaactcg tcacatatgt gcgtcaaaga 3462 0 gcaaagtttg attgctggat gttcgcgcac catctccaca ccctgcgccc gcaattctgc 3468 0 cagaaaagcg taggggtcag ttttttcact gtggtacatg gcatcataga taatcattgc 3474 0 agcgacacct gcctgtcctg catctgtgac ggatatatgc tcaagggcta cggccattgc 3480 0 gtgtttcaac ctctcatttt ccacctcaag caccacacga ttagcctcca gctcttctat 3486 0 gcgttttttt gctgctccca gctcaacacg cagctcctga tagttaatct cgctcattct 3492 0 ccttcctccc gcactgctgt tttatatgcc cgaagcacat gcgatgtttt tcctgacaca 3498 0 gtgcttctca gaaagaaaat tccactggtg tttattacca gatacgggtc agcaagacgc 3504 0 agcatatcca gtatgtgatt atgttttctt gtttccagca ccgtacttga aataagcata 3510 0 tgtgacacgg ggccgaaatc atgatatctg attttcatat catcaccctg ctgtaaaaat 3516 0 tacccgttat ctcctgtcgt tattttctgt atgacatcac gatgcttatt aatttcccgc 3522 0 agcgcggcgc ataagcgctc ccacttctga acctgacctt ttgcccggcg cagctcgcgg 3528 0 ttagccacat gcagcgatgg taaaatcaga ccatccggat gctttctgat gaacgacgac 3534 0 tgtgactgca ctgtgaccgc cacactttca gttttaattt cttcctgtgt ttccgcttcc 3540 0 cggactggta acgcaacacc tgccggctga ggaaaggctt taccatcggt ttccgttacc 3546 0 gatgcagctt tcggctctgc cggtaaatta tcgcccggta tgcagtaacg atatttaccg 3552 0 tcctgattta cgcgaatcag acgacctttg ctgacagcca tcgccagtga tgaattcgcc 3558 0 cggcgggagg taatcccgaa cattaacgcc agttcgtcag ccgactgagg accatgctgt 3564 0 tcaatcgcgt taatcagcat ctctgcagtg gtttttgggg ccgcttcagt tgcctcactc 3570 0 gtcagccacc acatcgaccc cttgttatca gcttcgccac gacgcttcag cttccagagt 3576 0 tcggtaacag catcgtcacg gctgatttca agacgggctg caatctcgtg cgacgaggct 3582 0 tttttcagtg ctttcagtgc gtcaaaaacg gtttccatta aattttcctc ccggtaaaaa 3588 0 ttacttctca actcagacaa aaccggccgc cttccggcgc tcatattcct gtttcagcaa 3594 0 ttcaattggc gttggccctg gcgggcgttt gggtgctgcc agttgtcgcc ggactggcgg 3600 0 aacactgagg ccattaccaa catgctttgc ccatttcgtc agctgccttt ccacaagccg 3606 0 ttttaactcc ccttcggtca tctggcgctc aatccccttt gaacgcatct cgaggcaaat 3612 0 gtggtacagc accggctgtg gccacgggta tttatcactc ccgtcgtacc gccaggattc 3618 0 attcctccag cgacggtact cctccatcac ggcatccacc gtcaggccaa atggatttgc 3624 0 cccgctctcc gaaatcaacg ccacaaactc agccagatcc ggaggccacg tttcacccgc 3630 0 ccggcagcgg tccatgcact gacggcagac ctgccggatt tgctgttcag tcatcgcgcc 3636 0 aatctgagca atccagagct tcgacggcgc agccccgttc ttctgggtcc agcggttcga 3642 0 atacacctcc cccataagtt cccacagctt ccaggccgtt tccgttgctg ataaatccgt 3648 0 tttcacgttc ccactgttca cgtgctgccc gaatttcctg aactgcccgt gatgcggtgc 3654 0 cacctggtgc tgcatggctt acccccttgc tgactggttt tacctgtgcc ctgacgtgct 3660 0 gcacgtgacg ggcaaatttc tgctcccact gaacctgcgt gaaaaccttc ccctccgcca 3666 0 tccagtaatc ccggaatgcg gcaagctcag caggtgtaaa ctcaggctca ggcagagcca 3672 0 taccccacac tgctgcccgc tgtcgaaaat ccggcgacgg ttgccagact ccagtcatcg 3678 0 gaaatttccc gatcggttcg ctcaggccgt ccaggtattc aggttcggct gtctgcaacg 3684 0 acgcgtcatt caactcaccg gtcgtagcac tctcgcgcat gcgcgcgtta tgtgtggggt 3690 0 ttaattcttt atctgtatct gtatctgtcg tgatttgtcg tgacatatgc gtgacgcgtc 3696 0 gtgactcatc gtgacaatca gtgttctgct tccgcagtct ttcccgctcc cgctgcgctc 3702 0 tcttgcgctc tgccggggat tttgcggttt gcgaaacatt accgttatcc tccttcatca 3708 0 cctggcgttt ttcccatccg gaaataagat caccatccag aactcgcccc tgcattgcat 3714 0 gcaaaattga atcaatcacg tcttccgtca catcaagcgc acttgctaaa tcttccgtcg 3720 0 tgacatcaat gtgaccacgt agtgacacgc cgtgacatgt cgtgacattt cgtgacgcac 3726 0 tcaccagaag gtggatatac accgccatca ctgttgcgat tggctgtcct gagaccctgg 3732 0 caatggttcg ccatttggga tcatttggca tgtcatgcca caatctgagc caggcattag 3738 0 ccatactcac ctcatctgat accgaacttt accctcgaac atccggaaga aatccggcat 3744 0 gaatattgtt ggtcaatgca cgacaacagc attaccaggc tgaccaccac tgttagtcag 3750 0 ggtgccccag gcgatcgccg ctgcgacaaa atcatccaca tctttcacca gccgatccct 3756 0 ccgttcgacg atctcacggt aatattcaga gctgtgactg cgcatacggg ccaccagcag 3762 0 aggcggcatt gccttttcga tcgccggtaa cagagcctga attttttcaa cagcatcagg 3768 0 ggtgtcttta tccagccaac ggaaaatttt ctgggtatta cgagccaggg cttccggatg 3774 0 gctgtcgtcg tacagttccg ggaacgtcat ccccagctcg aaataagtcc gggctatttc 3780 0 agctgcagga actttctcac cgtccggata ggcccaggca ttgatcgcca tgcggatgtg 3786 0 ctcatgtttg attttcatga atcccccttt ccttcgccct gagtggtatc cttctttttg 3792 0 taaagttctg ggttcaaaga taatttcccc ttggagtatg cagcagcttc cgcagccctc 3798 0 cccttcggaa ctatttcacc aggacgctta cgccacatgt aaatagcttc gcgggttatc 3804 0 ccataaaaat cggcaaccct ctgaacagaa ccaaaaaact ggacaagttc atcaactcgc 3810 0 attttacctc ccaaatctaa gtatttttag attacaagat aatttttttt aggtcaatgc 3816 0 aatctaaaat aatttatatt caatttgcag gagaaaatga tggaaagcct tggcttcagg 3822 0 cttaagagac ttagaaaaga taaggggctg acccaagtag aactgggtaa gctttcaggc 3828 0 gtgactgggg ttactatagg gtactgggag aaagatctaa acgaaccagg tagcaaagct 3834 0 ctaagtaagt tagcccaggc attaggaact actgagtcct atctcctata tggagtatcg 3840 0 tctcctgaat tatcttttgt acaaagtacc tcaggcacca agatccccta cctttcgtgg 3846 0 ggtgaggcga tttctttcct aatcttaaaa ggagagaaaa caatgggaaa tgtcgataga 3852 0 atcaccacat tctttgatgt cgaggaaggt gattttgccg tttcaatgcc tgatgacaca 3858 0 atgcataacc catcaggatc accgagtatc ccagttggtg ctactgtgat cctaaggcca 3864 0 ggagaaagtt ataaaaatgg cagcatcgtc gctgtaatag ttccggatcc gcttaaaaat 3870 0 gaaccatcta tgactataaa gaaattagtt attgatggga agcttgtgta tttaagccct 3876 0 ctcaatccac gctatcagtc atccttactt acaccagagt gtaaaattgt tgccgtagca 3882 0 aaaggtgtac agttcaactt ataacccgcc acgtccttta cttgaggtcg gcaatgccga 3888 0 cctttttttt aaattaatct agatttacct tgactgaaaa actaaatact tttagattta 3894 0 ttacatacca ccctacctcg ccccacagaa cgtcgggcaa tacctcgagt tacccggcag 3900 0 tggtcagggg ttaagtagcc agcccgaggc gtatgaacat gacggcggga acactttgta 3906 0 taacagcgca gcaggttttt agttccgcga cccggcgtta agggtaaatg aggtcaacat 3912 0 ggatatgctc aatcttggca acaatgaatc tctggtgtgc ggagtattcc ccaaccacga 3918 0 cggcacgttt accgcgatga cgtataccag aagtaaaacg tttaaaaccg aagctggcgc 3924 0 gcatcgctgg ttagcaagaa acgctaactg attagcgcca gtaaaaacag gtttccacag 3930 0 gttaatttac cctgaaaagt cagggcataa cacgaaagcg cacggcgaag ttagtctctc 3936 0 tgtataggtc gtcgttaaat ttaattcgac cgtgcgcttc tggttgtggc aatccgcgaa 3942 0 atggcgcggc ggtaagtatg gcggggttat tccttccccc gttgaggaca ccgggttgtc 3948 0 aggttgacca tacgcttaag tgacacccca gccacaacaa cctctgttat cacttttctg 3954 0 gtgattcggc ggaaatggat atccgccctt tttaaagtga attttgtgat gcggtgaatg 3960 0 cggctatgcg cacgcggaac agttaaagca gtaaggcggt cttttactgg cgtaacgagc 3966 0 atcaactaac ccgacgttaa ttgttaactg gttaacgtca cctggaggca ccaggcactg 3972 0 catcacaaaa ttcattgttg aggacgcgat aatggaaacg ttattaccaa acgttaatac 3978 0 gtctgaaggt tgttttgata ttggtgttct gctcagtaat aaagcgttta ctgaggatgc 3984 0 cattaatatg cggaaatatg agccttatct gctcaatgat aattccattc tttcccgaat 3990 0 tgcccttatt aaacttggta ttttcggaga acgtcaatga cttcagcatt tgcactggtg 3996 0 atgacggttt ttcttataac gggtgaatca cagaatgtta ttaccggaat ttatgccagt 4002 0 aaagaatcct gcctccaggc aagagacgag caaaaaattt ctggtgaatg cctaccggta 4008 0 aaaaaagtat cgctgtacct gaataacgaa acaccggctg gataacccgc cagccatatt 4014 0 aacgccatac caacggatta aaaatgccag caatggcagg gattcgttca ccctgaaatc 4020 0 tgtaatgagg ttaaaacaca atgagtaaaa tctttatttg cgctgctatt cctgacgaac 4026 0 aggccataaa agaagatagc gctgttgcgg tggccactgc cattgaagcc ggtgatgagc 4032 0 gtcgcgcacg cgcaaaattt cactggcaat ttctggagca attcccggca gctcaggact 4038 0 gcgcttataa atttattgtc tgcgaggata aacccggcat accccgccct gccctcgatt 4044 0 cctgggatac cgaatatatg caggaaaacc gctgggatga ggagtcagct tcctttgtac 4050 0 cggtcgaacc agaatccgat ccgatgaacg tcaattttga caagctgtcc cctgaagtac 4056 0 agaacgcagt cctggttaaa ttcgacacat gcgaaaacat caccgttgat atggtgatta 4062 0 gcgcacagga attactacag gaagacatgg caacattcgg cggacatatc gttgaagcgt 4068 0 tgatgaaaat gccagaagtt aacgccatgt atcctgaact taaactgcat gccatcgggt 4074 0 gggttaagca taaatgtgag cctggcgcta aatggcctga aattcaggca gagatgcgca 4080 0 tctggaaaaa acgtcgcgaa ggtgaacgca aggaaaccgg aaaatacacg tctgttgttg 4086 0 atctcgcccg cgccagagtc aaccaacaga accctgaaaa cgctgctgaa aaaaccgggg 4092 0 ctgtcactgt tgccattcgc cgcgaataca aacagacatg gaaaacactc gacaatgaac 4098 0 tggcctgcgc cctctggccc ggtgatgtgg atgcaggaaa cattgacggt accatccatc 4104 0 gctgggcgac aaatgaggtt atcgacaagg atcgcgaaga ctggaagcgt atctcagcat 4110 0 caatgcgcaa acagcccgaa gcacttggct atgaccgtca gactattttt ggccttgttc 4116 0 gcgaacgtcc gatcgatatt cacaaagatc ccgttgcact gaacaaatat atcagtgaat 4122 0 acctgacgac aaagggcgtg tttgaacatg aagaaacaga ccagagctct actgatgctc 4128 0 tccagccgtc agcagcacaa actgctccag tggagacggc agaatccgat actcaaaaaa 4134 0 atgaaatcct ggtggaagct gaaccatctg tagagcgtga aggaccattt tatttcgtct 4140 0 ttaccgataa gggcggggaa aaatacggca gggcaaacaa actttctggt ctggacaagg 4146 0 cgctggctgc cggcggtacc gaaatctcaa aagaagaata ttttgcccga aaaaatggca 4152 0 catacacggg cttaccgcaa aatgtggata ccgctgaaga ttccgaacaa tcagagccgg 4158 0 taaaagttac cgctgacgaa gtaaacaaaa ttatgcaggc agccaatatc agccagcctg 4164 0 acgccgataa attgcttgct gcatcacgtg gtgaatttgt tgaagggatt agcgacccga 4170 0 atgatccgaa atgggtgaaa gggatccaga gtcgcgacgc tgaggaccag aatcagccca 4176 0 acgtgaaaca aaatgagcca gaagcggaac aaaacagccc ggatacgcaa caaaacgggc 4182 0 cagaagaaca acaaccagaa ccagcagtgc aacaggaact ggaaaaagtt tgcaccgcat 4188 0 gcggtcagac cggtggcggc aactgtcctg actgtggtgc ggtgatgggg aacgcaacct 4194 0 acctggaaac attcgatgaa gagaatcagg ctgaagctca gaaaaatgat ccggaggaaa 4200 0 tggaaggcac tgaacatctg cacaaggaga acactggcag cgatcagtat cacgccagcg 4206 0 ataataaaac tggcgaaaca gcaaatccct taattaaagt gaacggtcat catgaaatct 4212 0 catccaccag caggttgtgg caccatctga tgattgacct tgaaacaatg ggaaaaaatc 4218 0 ctgatgcgcc aataaactct atagccggta agttttttga tccggcaacc ggagagatgg 4224 0 ggccagaatt cagcaaaact atcgatctgg aaaccgcagg tggggtcatc gatcgggaca 4230 0 ccattaagtg gtggctgaaa cagtcacgcg aagcacaatc ctccattctg accgatgaaa 4236 0 tcacgttgga tgatgcactg ctgcaattcg gggaatttta tcgacgaaaa ctccggtgaa 4242 0 ttttctgttc aggtctgggg taacggtgca actttcgaca acgtgatttt acgccgttca 4248 0 tatgaacggc aggggatccc ctgcccgtgg cgttacacca atgatcgcga tgtaagaacg 4254 0 atggttgctc tgggactggt gatggatttc gacgcaagaa cgactattcc attcgaaggt 4260 0 gaacgccata acgccctgca cgatgcgcgt taccaggcaa aatacgtttc agccatctgg 4266 0 caaaaactgc tcccgagtca ggctgatttt taatgttcaa cccggatcgc cgctaacggc 4272 0 atatagttag cggcggttgt gagatatagc tatgagcagc atatttttaa ccgaaaatga 4278 0 attgcaaacg ttaacgggct gcaaatatgc aagccaccag cgcaactggt taataaaaaa 4284 0 tgggcttccg ttctatacca atcgtagtgg aaaaccgatc gtcagtcggg aactgtttac 4290 0 ctgtataaaa actttaccac cacgtgaggc tgaacctgat ttcggtgcga tctaatggga 4296 0 agacgaagga aaaatcccga acacgaaaaa ttaccgccaa aggtataccc caataaatat 4302 0 agtgtatgga aaccgacatc cagagaatct gtaaccttaa ctgcaatcga ggatggttta 4308 0 gccgcattat ggaaaaagta tgaagaaacg gttaaccatc gcgatcgcgc aatgacattt 4314 0 gggcgtttgt gggaaaaatt tctcgccagc gcctattaca gcgagcttag tcctagaact 4320 0 caaaaagatt atctgcaaca tcaaaaaaag ctgctggccg tattcggtaa ggtgctggcc 4326 0 gattctgtaa aaccagagca catcagacga tacatggaca aaagaggcga gcagagtaaa 4332 0 acgcaggcaa accatgaaaa aagcagtatg tcgcgcgttt atagttgggg gtatgagcga 4338 0 ggatacgtga aggctaaccc atgtgcaggt gtaagtaaat tcaaggccaa aaaccgcgaa 4344 0 cgatatgtaa ccgacaaaga ataccaggca gtattaagcg ttgcacctct tcctgttttt 4350 0 atcgcaatgg aaattgccta tctgtgtgca gcgagggttt ccgatgtgtt atcgctgaaa 4356 0 tgggagcaga ttggaaacga cgggatcttt atccagcaag ggaaaacagg gaaaaaacag 4362 0 ataaaagcat ggagtccacg attacaggcg gcgatcgaaa aagcaaaaca gttaccaaca 4368 0 tccgcctatg taatcagcaa tcaatacggc aaccgatata tgtacaaagg ctttaacgaa 4374 0 atgtgggtag aagcaagaaa tcacgcaggc aaaatttcag gtattttaac cgacttcacc 4380 0 tttcatgatc tgaaggcgaa aggaatttca gactatgaag gaagcagccg ggataagcaa 4386 0 cttttctctg gtcacaaaac cgaagggcaa gtgctaatct atgacaggaa ggttaaagtt 4392 0 tcaccaacac ttgatgtccc gttacctgaa aatattccaa gaaaatattc caagtaattc 4398 0 caagtgtgat ttttgtcact gacttaatga tgtgtaagtg attgaattt 4402 9 <210> 756 <211> 218 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(567..1220) <400> 756 Met Ser Ile Ile Lys Asn Cys Leu Ser Leu Ile Asn Asn Ala Leu Asn 1 5 10 15 Ile Gln Lys Thr Ser Tyr Ser Leu Thr Lys Met Glu Gln Ala Gly Lys 20 25 30 Leu Leu Asn Arg Lys Ile Thr Pro Glu Asn Thr Pro Pro Met Leu Leu 35 40 45 Ser Tyr Arg Asn Ala Asp Leu Thr Gln Glu Lys Asn Ile Thr Glu Arg 50 55 60 Val Leu Ser Ile Phe Lys Ile Lys Arg Asp Phe Val Ala Val Arg Ile 65 70 75 80 Gln Asn Asn Gln Phe Thr Asp Leu Lys Asn Lys Lys Ile Gln Gly His 85 90 95 Gln Asn Thr Val Ala Ser Val Met Asp Trp Tyr Asn Pro Gln Lys Asn 100 105 110 Ala Leu Gly Ile Thr Met Gly Thr Pro Arg Lys Ser Ala Asp Ile Ala 115 120 125 Lys Glu Glu His Arg Asn Ala Leu Asn Phe Met Ile Met Glu Lys Asn 130 135 140 Thr Phe His Glu Lys Ile Leu Asn Ser Asn Asp Asn Leu Gln Lys Ser 145 150 155 160 Tyr Ser Lys Thr Glu Asp Ser Ser Trp Val Ala Ala Ser Val Gly Ser 165 170 175 Leu Leu Asp Lys Gly Ala Lys Val Tyr Pro Asp Thr Ser Cys Ser Leu 180 185 190 Arg Leu Gly Glu Pro Phe Ile Phe Thr Leu Pro Glu Ser Val Arg Val 195 200 205 Asp Val Asp Ile Tyr Pro Leu Lys Lys * 210 215 <210> 757 <211> 338 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1545..2558) <400> 757 Met Ile Asn Asn Val Ser Ser Leu Phe Pro Thr Val Asn Arg Asn Ile 1 5 10 15 Thr Ala Val Tyr Lys Lys Ser Ser Phe Ser Val Ser Pro Gln Lys Ile 20 25 30 Thr Leu Asn Pro Val Lys Ile Ser Ser Pro Phe Ser Pro Ser Ser Ser 35 40 45 Ser Ile Ser Ala Thr Thr Leu Phe Arg Ala Pro Asn Ala His Ser Ala 50 55 60 Ser Phe His Arg Gln Ser Thr Ala Glu Ser Ser Leu His Gln Gln Leu 65 70 75 80 Pro Asn Val Arg Gln Arg Leu Ile Gln His Leu Ala Glu His Gly Ile 85 90 95 Lys Pro Ala Arg Ser Met Ala Glu His Ile Pro Pro Ala Pro Asn Trp 100 105 110 Pro Ala Pro Pro Pro Pro Val Gln Asn Glu Gln Ser Arg Pro Leu Pro 115 120 125 Asp Val Ala Gln Arg Leu Val Gln His Leu Ala Glu His Gly Ile Gln 130 135 140 Pro Ala Arg Asn Met Ala Glu His Ile Pro Pro Ala Pro Asn Trp Pro 145 150 155 160 Ala Pro Pro Leu Pro Val Gln Asn Glu Gln Ser Arg Pro Leu Pro Asp 165 170 175 Val Ala Gln Arg Leu Val Gln His Leu Ala Glu His Gly Ile Gln Pro 180 185 190 Ala Arg Ser Met Ala Glu His Ile Pro Pro Ala Pro Asn Trp Pro Ala 195 200 205 Pro Pro Pro Pro Val Gln Asn Glu Gln Ser Arg Pro Leu Pro Asp Val 210 215 220 Ala Gln Arg Leu Met Gln His Leu Ala Glu His Gly Ile Gln Pro Ala 225 230 235 240 Arg Asn Met Ala Glu His Ile Pro Pro Ala Pro Asn Trp Pro Ala Pro 245 250 255 Thr Pro Pro Val Gln Asn Glu Gln Ser Arg Pro Leu Pro Asp Val Ala 260 265 270 Gln Arg Leu Met Gln His Leu Ala Glu His Gly Ile Gln Pro Ala Arg 275 280 285 Asn Met Ala Glu His Ile Pro Pro Ala Pro Asn Trp Pro Ala Pro Thr 290 295 300 Pro Pro Val Gln Asn Glu Gln Ser Arg Pro Leu Pro Asp Val Ala Gln 305 310 315 320 Arg Leu Met Gln His Leu Ala Glu His Gly Ile Asn Thr Ser Lys Arg 325 330 335 Ser * <210> 758 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2684..2953) <400> 758 Met Asn Ile Leu Lys Lys Leu Met Gln Arg Leu Cys Gly Cys Gly Lys 1 5 10 15 His Asp Asp Arg Glu His Gly Glu Leu Leu Thr Ala Gln Leu Arg Leu 20 25 30 Gly Pro Ala Asp Ile Leu Glu Ser Asp Glu Asn Gly Ile Ile Pro Glu 35 40 45 Gln Asp Arg Val Ile Thr Gln Val Val Ile Leu Asp Ala Asp Lys Lys 50 55 60 Gln Ile Gln Cys Val Val Arg Pro Leu Gln Ile Leu Arg Ala Asp Gly 65 70 75 80 Thr Trp Glu Asn Ile Gly Gly Met Lys * 85 <210> 759 <211> 438 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2955..4268) <400> 759 Met Ala Val Lys Ile Ser Gly Val Leu Lys Asp Gly Thr Gly Lys Pro 1 5 10 15 Val Glu Asn Cys Thr Ile Gln Leu Lys Ala Arg Arg Asn Ser Ala Thr 20 25 30 Val Val Val Asn Thr Val Ala Ser Glu Asn Pro Asp Glu Ala Gly Arg 35 40 45 Tyr Ser Met Asp Val Glu Tyr Gly Gln Tyr Ser Val Ile Leu Leu Val 50 55 60 Glu Gly Phe Pro Pro Ser His Ala Gly Thr Ile Thr Val Tyr Glu Asp 65 70 75 80 Ser Gln Pro Gly Thr Leu Asn Asp Phe Leu Gly Ala Met Ser Glu Asp 85 90 95 Asp Val Arg Pro Glu Ala Leu Arg Arg Phe Glu Leu Met Val Glu Glu 100 105 110 Ala Ala Arg His Ala Glu Glu Ala Lys Lys Asn Ala Gly Glu Ala Glu 115 120 125 Thr Ser Ala Arg Asn Ala Gly Ile Ser Ala Ser Gln Ala Glu Glu Ser 130 135 140 Ala Ala Asn Ala Asp Thr Ser Ala Gly Asp Ala Ser Glu Ser Ala Arg 145 150 155 160 Gln Ala Ala Glu Ser Ala Ala Ala Ala Lys Gln Ser Glu Glu Ala Ser 165 170 175 Ser Ser Ser Ala Ser Ala Ala Ala Gln Lys Ala Ser Glu Ser Ser Gln 180 185 190 Ser Ala Ala Asp Ala Glu Leu Ser Lys Lys Thr Ala Glu Ser Ala Ala 195 200 205 Gly Asn Ala Ala Arg Asp Ala Thr Thr Ala Thr Glu Lys Ala Arg Glu 210 215 220 Ser Ala Glu Ser Ala Gln Ser Ala Glu Gln Ser Arg Ile Ala Ala Glu 225 230 235 240 Glu Ala Val Asn Arg Ile Pro Thr Val Val Gly Pro Pro Gly Pro Lys 245 250 255 Gly Glu Pro Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp Lys Gly 260 265 270 Glu Arg Gly Asp Thr Gly Pro Val Gly Ala Thr Gly Glu Arg Gly Pro 275 280 285 Ala Gly Asp Ala Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp Arg 290 295 300 Gly Glu Arg Gly Glu Thr Gly Leu Thr Gly Asn Ala Gly Pro Gln Gly 305 310 315 320 Pro Lys Gly Asp Thr Gly Ala Ala Gly Pro Ala Gly Pro Gln Gly Pro 325 330 335 Lys Gly Glu Thr Gly Ala Ala Gly Pro Val Gly Ala Thr Gly Pro Gln 340 345 350 Gly Pro Lys Gly Asp Pro Gly Glu Thr Gln Ile Arg Phe Arg Leu Gly 355 360 365 Pro Ala Ser Ile Ile Glu Thr Asn Ser His Gly Trp Phe Pro Gly Thr 370 375 380 Asp Gly Ala Leu Ile Thr Gly Leu Thr Phe Leu Ala Pro Lys Asp Thr 385 390 395 400 Thr Arg Val Gln Gly Phe Phe Gln His Leu Gln Val Arg Phe Gly Asp 405 410 415 Gly Pro Trp Gln Asp Val Lys Gly Leu Asp Glu Val Gly Ser Asp Thr 420 425 430 Gly Arg Thr Gly Glu * 435 <210> 760 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4333..4932) <400> 760 Met Arg Lys Leu Tyr Ala Ala Ile Leu Ser Ala Ala Ile Cys Leu Ala 1 5 10 15 Val Ser Gly Ala Pro Ala Trp Ala Ser Glu Gln Gln Ala Thr Leu Ser 20 25 30 Ala Gly Tyr Leu His Ala Arg Thr Ser Ala Pro Gly Ser Asp Asn Leu 35 40 45 Asn Gly Ile Asn Val Lys Tyr Arg Tyr Glu Phe Thr Asp Thr Leu Gly 50 55 60 Leu Val Thr Ser Phe Ser Tyr Ala Gly Asp Lys Asn Arg Gln Leu Thr 65 70 75 80 Arg Tyr Ser Asp Thr Arg Trp His Glu Asp Ser Val Arg Asn Arg Trp 85 90 95 Phe Ser Val Met Ala Gly Pro Ser Val Arg Val Asn Glu Trp Phe Ser 100 105 110 Ala Tyr Ala Met Ala Gly Val Ala Tyr Ser Arg Val Ser Thr Phe Ser 115 120 125 Gly Asp Tyr Leu Arg Val Thr Asp Asn Lys Gly Lys Thr His Asp Val 130 135 140 Leu Thr Gly Ser Asp Asp Gly Arg His Ser Asn Thr Ser Leu Ala Trp 145 150 155 160 Gly Ala Gly Val Gln Phe Asn Pro Thr Glu Ser Val Ala Ile Asp Ile 165 170 175 Ala Tyr Glu Gly Ser Gly Ser Gly Asp Trp Arg Thr Asp Gly Phe Ile 180 185 190 Val Gly Val Gly Tyr Lys Phe * 195 <210> 761 <211> 809 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5000..7426) <400> 761 Met Glu Arg Ala Asp Ala Asp Val Cys Ala Gly Pro Ser Val Arg Cys 1 5 10 15 Gly Val Ala Tyr Thr Ser Ser Asp Val Val Val Asp Asp Asn Gly Val 20 25 30 Gly Phe Arg Tyr Ser Phe Ser Ala Leu Lys Asp Arg His Thr Ala Val 35 40 45 Glu Val Asn Tyr Thr Asp Pro Gln Asn Gly Trp Gln Thr Ser Thr Glu 50 55 60 Leu Val Glu Asp Pro Glu Ala Ile Leu Arg Tyr Gly Arg Asn Leu Leu 65 70 75 80 Lys Met Asp Ala Phe Gly Cys Thr Ser Arg Gly Gln Ala His Arg Ala 85 90 95 Gly Leu Trp Val Ile Lys Thr Gly Leu Leu Glu Thr Gln Thr Val Asp 100 105 110 Phe Thr Leu Gly Ser Gln Gly Leu Arg His Thr Pro Gly Asp Ile Ile 115 120 125 Glu Ile Cys Asp Asn Asp Tyr Ala Gly Thr Met Thr Gly Gly Arg Ile 130 135 140 Leu Ser Ile Asp Ala Ala Ser Arg Thr Leu Thr Leu Asp Arg Glu Val 145 150 155 160 Thr Leu Pro Glu Thr Gly Ala Ala Thr Val Asn Leu Ile Asn Gly Ser 165 170 175 Gly Lys Pro Val Ser Val Ala Ile Thr Ala His Pro Ala Pro Asp Arg 180 185 190 Ile Gln Val Ser Thr Leu Pro Asp Gly Val Glu Thr Tyr Gly Val Trp 195 200 205 Gly Leu Ser Leu Pro Ser Leu Arg Arg Arg Leu Phe Arg Cys Val Ser 210 215 220 Ile Arg Glu Asn Thr Asp Gly Thr Phe Ala Ile Thr Ala Val Gln His 225 230 235 240 Val Pro Glu Lys Glu Ala Ile Val Asp Asn Gly Ala His Phe Asp Gly 245 250 255 Asp Gln Ser Gly Thr Leu Asn Ser Val Ile Pro Pro Ala Val Gln His 260 265 270 Leu Thr Val Glu Val Ser Ala Ala Asp Ser Gln Tyr Leu Ala Gln Ala 275 280 285 Lys Trp Asp Thr Pro Arg Val Val Lys Gly Val Arg Phe Ser Leu Arg 290 295 300 Leu Thr Ser Gly Ser Gly Gln Asp Ser Arg Leu Val Thr Thr Ala Ile 305 310 315 320 Thr Ala Asp Thr Glu His Arg Phe Ser Gly Leu Pro Leu Gly Glu Tyr 325 330 335 Thr Leu Thr Val Arg Ala Ile Asn Ser Tyr Gly Gln Gln Gly Glu Pro 340 345 350 Ala Ile Thr Thr Phe Arg Ile Asn Ala Pro Ala Lys Pro Ala Thr Ile 355 360 365 Glu Leu Thr Pro Gly Tyr Phe Gln Ile Thr Ala Val Pro Val Leu Ala 370 375 380 Val Tyr Asp Pro Thr Val Gln Phe Glu Phe Trp Phe Ser Glu Lys Arg 385 390 395 400 Ile Thr Asn Thr Ala Gln Val Glu Lys Ser Ala Arg Tyr Leu Gly Ser 405 410 415 Gly Ser Gln Trp Thr Val Gln Gly Ser Arg Ile Lys Pro Gly Thr Asp 420 425 430 Phe Trp Phe Tyr Val Arg Ser Val Asn Leu Val Gly Lys Ser Ala Phe 435 440 445 Val Glu Val Ser Gly Gln Pro Ser Asn Asp Gly Glu Gly Tyr Leu Glu 450 455 460 Phe Phe Arg Glu Lys Ile Gly Lys Leu His Leu Ala Gln Gly Leu Trp 465 470 475 480 Glu Leu Ile Asp Asn Ser Gln Leu Ala Asp Glu Met Ala Glu Met Lys 485 490 495 Thr Thr Ile Thr Glu Thr Arg Asn Glu Ile Thr Gln Thr Val Ser Lys 500 505 510 Thr Leu Glu Asn Gln Ser Ala Thr Ile Gln Gln Ile Gln Arg Val Gln 515 520 525 Lys Asp Thr Asn Asp Asp Leu Ala Ala Leu Tyr Met Leu Lys Val Gln 530 535 540 Lys Thr Lys Asp Gly Ile Pro Tyr Val Ala Gly Ile Gly Ala Gly Ile 545 550 555 560 Glu Asp Thr Asp Gly Gln Pro Leu Ser Asn Ile Leu Leu Leu Ala Asp 565 570 575 Arg Ile Ala Met Ile Asn Pro Glu Ser Gly Asn Ser Thr Pro Leu Phe 580 585 590 Val Ala Gln Gly Asn Gln Leu Phe Met Asn Asp Val Phe Leu Lys Arg 595 600 605 Leu Phe Ala Val Ser Ile Thr Ser Ser Gly Asn Pro Pro Thr Phe Ser 610 615 620 Leu Thr Pro Asp Gly Arg Leu Thr Ala Lys Asn Ala Asp Ile Ser Gly 625 630 635 640 Ser Val Asn Ala Asn Ser Gly Thr Leu Asn Asn Val Thr Ile Asn Glu 645 650 655 Asn Cys Gln Ile Lys Gly Lys Leu Ser Ala Asn Gln Ile Glu Gly Asp 660 665 670 Ile Val Lys Thr Val Ser Lys Ser Phe Pro Arg Thr Ser Thr Tyr Ala 675 680 685 Ser Gly Thr Ile Thr Val Arg Ile Ser Asp Asp Gln Lys Phe Asp Arg 690 695 700 Gln Val Met Ile Pro Pro Val Leu Phe Arg Gly Gly Lys His Glu Asn 705 710 715 720 Phe Asn Ser Asn Asn Gln Gln Ser Tyr Trp Tyr Ser Thr Cys Arg Leu 725 730 735 Arg Val Thr Arg Asn Gly Gln Glu Ile Phe Asn Gln Ser Thr Thr Asp 740 745 750 Ala Gln Gly Val Phe Ser Ser Val Ile Asp Met Pro Ala Gly Gln Gly 755 760 765 Thr Leu Thr Leu Thr Phe Thr Val Ser Ser Ser Gly Ala Asn Asn Trp 770 775 780 Thr Pro Thr Thr Ser Ile Ser Asp Leu Leu Val Val Val Met Lys Lys 785 790 795 800 Ser Thr Ala Gly Ile Ser Ile Ser * 805 <210> 762 <211> 392 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7303..8478) <400> 762 Val Gly Lys Gly Gly Gly Lys Gly His Thr Pro Val Glu Ala Lys Asp 1 5 10 15 Asn Leu Lys Ser Thr Gln Met Met Ser Val Ile Asp Ala Ile Gly Glu 20 25 30 Gly Pro Ile Glu Gly Pro Val Lys Gly Leu Gln Ser Ile Leu Val Asn 35 40 45 Lys Thr Pro Leu Thr Asp Thr Asp Gly Asn Pro Val Ile His Gly Val 50 55 60 Thr Ala Val Trp Arg Ala Gly Glu Gln Glu Gln Thr Pro Pro Glu Gly 65 70 75 80 Phe Glu Ser Ser Gly Ser Glu Thr Ala Leu Gly Val Glu Val Thr Lys 85 90 95 Ala Lys Pro Val Thr Arg Thr Ile Thr Ser Ala Asn Ile Asp Arg Leu 100 105 110 Arg Val Thr Phe Gly Val Gln Ser Leu Val Gln Thr Thr Ser Gln Gly 115 120 125 Asp Arg Asn Pro Ala Ser Val Arg Leu Leu Ile Gln Leu Gln Arg Asn 130 135 140 Gly Asn Trp Val Thr Glu Lys Asp Val Thr Ile Asn Gly Lys Thr Thr 145 150 155 160 Ser Gln Phe Leu Ala Ser Val Ile Leu Asp Asn Leu Pro Pro Arg Pro 165 170 175 Phe Asn Ile Arg Met Val Arg Glu Thr Ala Asp Ser Thr Thr Asp Gln 180 185 190 Leu Gln Asn Arg Thr Leu Trp Ser Ser Tyr Thr Glu Ile Ile Asp Val 195 200 205 Lys Gln Cys Tyr Pro Asn Thr Ala Ile Val Gly Leu Gln Val Asp Ala 210 215 220 Glu Gln Phe Gly Gly Gln Gln Met Thr Val Asn Tyr His Ile Arg Gly 225 230 235 240 Arg Ile Ile Gln Val Pro Ser Asn Tyr Asp Pro Glu Lys Arg Thr Tyr 245 250 255 Ser Gly Ile Trp Asp Gly Ser Leu Lys Pro Ala Tyr Ser Asn Asn Pro 260 265 270 Ala Trp Cys Leu Trp Asp Met Leu Thr His Pro Arg Tyr Gly Met Gly 275 280 285 Lys Arg Leu Gly Ala Ala Asp Val Asp Lys Trp Ala Leu Tyr Ala Ile 290 295 300 Ala Gln Tyr Cys Asp Gln Thr Val Pro Asp Gly Phe Gly Gly Thr Glu 305 310 315 320 Pro Arg Met Thr Phe Asn Ala Tyr Leu Ser Gln Gln Arg Lys Ala Trp 325 330 335 Asp Val Leu Ser Asp Phe Cys Ser Ala Met Arg Cys Met Pro Val Trp 340 345 350 Asn Gly Gln Thr Leu Thr Phe Val Gln Asp Arg Pro Ser Asp Val Val 355 360 365 Trp Pro Thr Pro Ala Val Met Trp Trp Trp Met Ile Thr Ala Trp Gly 370 375 380 Phe Ala Thr Ala Ser Ala Pro * 385 390 <210> 763 <211> 226 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8719..9396) <400> 763 Met Ala Thr Thr Asn Ala Phe Cys Leu Ala Ser Pro Pro Leu Ala Arg 1 5 10 15 Ile Cys Leu His Gly Asp Leu Gln Arg Phe Gly Arg Arg Leu Ser Leu 20 25 30 Tyr Val Asn Thr Ala Ala Glu Ala Ile Arg Ala Leu Ser Leu Gln Met 35 40 45 Pro Gly Phe Arg Arg Gln Met Asn Glu Gly Trp Tyr Gln Ile Arg Ile 50 55 60 Arg Gly Glu Asp Thr Ala Pro Glu Ala Val Tyr Ala Arg Leu His Glu 65 70 75 80 Pro Leu Gly Glu Gly Ala Val Ile His Ile Val Pro Arg Leu Ala Gly 85 90 95 Ala Gly Lys Gly Gly Leu Gln Ile Val Leu Gly Ala Ala Ala Ile Val 100 105 110 Gly Ser Phe Phe Thr Ala Gly Ala Thr Met Ala Leu Trp Gly Ala Ala 115 120 125 Leu Ser Ala Gly Gly Leu Thr Ala Thr Thr Met Leu Phe Ser Leu Gly 130 135 140 Ala Ser Met Ile Leu Gly Gly Val Ala Gln Met Leu Ala Pro Lys Ala 145 150 155 160 Lys Thr Pro Glu Tyr Arg Ala Thr Asp Asn Gly Lys Gln Asn Thr Tyr 165 170 175 Phe Ser Ser Leu Asp Asn Met Ile Ala Gln Gly Asn Pro Met Pro Val 180 185 190 Pro Tyr Gly Glu Met Leu Val Gly Ser Arg Arg Ile Ser Gln Asp Ile 195 200 205 Ser Thr Arg Asp Glu Gly Gly Asp Gly Lys Val Val Val Ile Gly Arg 210 215 220 Gly * 225 <210> 764 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9294..9863) <400> 764 Met Gln Gly Glu Ile Val Ala Leu Val His Ser His Pro Gly Gly Leu 1 5 10 15 Pro Trp Leu Ser Glu Ala Asp Arg Arg Leu Gln Ile Lys Ser Ala Leu 20 25 30 Pro Trp Trp Leu Val Cys Arg Gly Glu Ile His Lys Phe Arg Cys Val 35 40 45 Pro His Leu Thr Gly Arg Arg Phe Glu His Gly Val Thr Asp Cys Tyr 50 55 60 Thr Leu Phe Arg Asp Ala Tyr His Leu Ala Gly Ile Thr Leu Pro Asp 65 70 75 80 Phe Glu Arg Glu Asp Asp Trp Trp Arg Asn Gly Gln Asn Leu Tyr Leu 85 90 95 Asp Asn Met Ala Ala Thr Gly Phe Tyr Arg Val Pro Leu Ser Ser Ala 100 105 110 Gln Ala Gly Asp Ile Leu Leu Cys Cys Phe Gly Ala Ser Val Ala Asn 115 120 125 His Ala Ala Ile Tyr Cys Gly Asn Gly Glu Leu Leu His His Leu Pro 130 135 140 Glu Gln Leu Ser Lys Arg Glu Arg Tyr Ser Glu Lys Trp Gln Arg Arg 145 150 155 160 Thr His Ser Val Trp Arg His Arg His Trp His Ala Ser Ala Phe Thr 165 170 175 Gly Ile Cys Asn Asp Leu Ala Ala Ala Ser Ala Cys Thr * 180 185 <210> 765 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10048..10746) <400> 765 Met Gln Asp Ile His Gly Glu Ser Leu Ile Glu Ser Val Lys Ser Glu 1 5 10 15 Gln Ser Pro Arg Val Val Leu Trp Glu Ile Asp Leu Thr Val Gln Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Leu Asn Glu Lys Gly Glu Ala 35 40 45 Val Thr Trp Gln Gly Arg Glu Tyr Gln Ala Tyr Pro Ile Asp Gly Ser 50 55 60 Gly Phe Glu Met Asn Gly Lys Gly Ser Ser Ala Arg Pro Ser Leu Thr 65 70 75 80 Val Ser Asn Leu Phe Gly Leu Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Ala Thr Val Val Arg Arg Arg Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Ala Gly Asn Pro Glu Ala Asp Pro Glu 115 120 125 Gln Glu Leu Ser Asp Arg Trp Val Val Glu Gln Met Ser Glu Leu Thr 130 135 140 Ala Met Thr Ala Ser Phe Val Leu Ala Thr Pro Thr Glu Thr Asp Gly 145 150 155 160 Ala Leu Phe Pro Gly Arg Ile Met Leu Ala Asn Thr Cys Met Trp Asp 165 170 175 Tyr Arg Gly Asp Glu Cys Gly Tyr Asn Gly Pro Ala Val Ala Asp Glu 180 185 190 Phe Asp Asn Pro Thr Thr Asp Ile Arg Lys Asp Arg Cys Ser Lys Cys 195 200 205 Met Arg Gly Cys Glu Met Arg Gly Met Val Ala Asn Phe Gly Gly Phe 210 215 220 Leu Ser Ile Asn Lys Leu Ser Gln * 225 230 <210> 766 <211> 110 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10746..11075) <400> 766 Met Lys Thr Phe Arg Trp Lys Val Lys Pro Asp Met Glu Val Asn Ser 1 5 10 15 Gln Pro Ser Val Arg Glu Val Arg Phe Gly Asp Gly Tyr Ser Gln Arg 20 25 30 Met Ala Ala Gly Leu Asn Ala Asp Leu Lys Thr Tyr Arg Val Thr Leu 35 40 45 Ser Val Thr Arg Glu Glu Ala Arg His Leu Glu Ala Phe Leu Ala Glu 50 55 60 His Gly Gly Trp Lys Ala Phe Leu Trp Lys Pro Pro Tyr Ala Tyr Arg 65 70 75 80 Gln Ile Lys Val Thr Cys Ala Gly Trp Ser Ala Arg Val Gly Met Leu 85 90 95 Arg Val Glu Phe Ser Ala Glu Phe Lys Gln Val Val Asn * 100 105 <210> 767 <211> 255 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11072..11836) <400> 767 Val Tyr Gly Asp Asn Pro Asp Ala Leu Ala Lys Ala Thr Ser Ala Leu 1 5 10 15 Lys Asn Thr Trp Ser Ala Glu Glu Gln Leu Arg Gly Ser Trp Met Ala 20 25 30 Gly Leu Lys Ser Gly Trp Gly Glu Trp Ala Glu Ser Ala Thr Asp Ser 35 40 45 Phe Ser Gln Val Lys Ser Ala Ala Thr Gln Thr Phe Asp Gly Ile Ala 50 55 60 Gln Asn Met Ala Ala Met Leu Thr Gly Ala Glu Ala Asp Trp Arg Gly 65 70 75 80 Phe Thr Arg Ser Val Leu Ser Met Met Thr Glu Ile Leu Leu Lys Gln 85 90 95 Ala Met Val Gly Ile Val Gly Arg Ile Gly Ser Ala Ile Gly Gly Ala 100 105 110 Phe Gly Gly Gly Ala Ser Ala Ser Thr Gly Thr Ala Ile Gln Ala Ala 115 120 125 Ala Ala Asn Phe His Phe Ala Thr Gly Gly Phe Thr Gly Thr Gly Gly 130 135 140 Lys Tyr Glu Pro Ala Gly Ile Val His Arg Gly Glu Phe Val Phe Thr 145 150 155 160 Lys Glu Ala Thr Ser Arg Ile Gly Val Gly Asn Leu Tyr Arg Leu Met 165 170 175 Arg Gly Tyr Ala Glu Gly Gly Tyr Val Gly Gly Ala Gly Ser Pro Ala 180 185 190 Gln Met Arg Arg Thr Glu Gly Ile Asn Phe Asn Gln Asn Asn His Val 195 200 205 Val Ile Gln Asn Asp Gly Thr Asn Gly Gln Ala Gly Pro Gln Leu Met 210 215 220 Lys Ala Val Tyr Asp Met Ala Arg Lys Gly Ala Gln Asp Glu Leu Arg 225 230 235 240 Leu Gln Leu Arg Asp Gly Gly Met Leu Ser Gly Ser Arg Arg * 245 250 <210> 768 <211> 621 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11788..13650) <400> 768 Met Ser Gln Pro Val Gly Asp Leu Val Ile Asp Leu Ser Leu Asp Ala 1 5 10 15 Val Arg Phe Asp Glu Gln Met Ser Arg Val Arg Arg His Phe Ser Gly 20 25 30 Leu Asp Thr Asp Val Arg Lys Thr Ala Ser Ala Val Glu Gln Gly Leu 35 40 45 Ser Arg Gln Ala Leu Ala Ala Gln Lys Ala Gly Ile Ser Val Gly Gln 50 55 60 Tyr Lys Ala Ala Met Arg Thr Leu Pro Ala Gln Phe Thr Asp Ile Ala 65 70 75 80 Thr Gln Leu Ala Gly Gly Gln Asn Pro Trp Leu Ile Leu Leu Gln Gln 85 90 95 Gly Gly Gln Val Lys Asp Ser Phe Gly Gly Met Ile Pro Met Phe Arg 100 105 110 Gly Leu Ala Gly Ala Ile Thr Leu Pro Met Val Gly Val Thr Ser Leu 115 120 125 Ala Val Ala Thr Gly Ala Leu Val Tyr Ala Trp Tyr Gln Gly Asp Ser 130 135 140 Thr Leu Ser Ala Phe Asn Lys Thr Leu Val Leu Ser Gly Asn Gln Ser 145 150 155 160 Gly Leu Thr Ala Asp Arg Met Leu Thr Leu Ser Arg Ala Gly Gln Ala 165 170 175 Ala Gly Leu Thr Phe Asn Gln Ala Arg Glu Ser Leu Ala Ala Leu Val 180 185 190 Asn Ala Gly Val Arg Gly Gly Glu Gln Phe Asp Ala Ile Asn Gln Ser 195 200 205 Val Ala Arg Phe Ala Ser Ala Ser Gly Val Glu Val Asp Lys Val Ala 210 215 220 Glu Ala Phe Gly Lys Leu Thr Thr Asp Pro Thr Ser Gly Leu Ile Ala 225 230 235 240 Met Val Arg Gln Phe Arg Asn Val Thr Ala Glu Gln Ile Ala Tyr Val 245 250 255 Ala Gln Leu Gln Arg Ser Gly Asp Glu Ala Gly Ala Leu Gln Ala Ala 260 265 270 Asn Asp Ile Ala Thr Lys Gly Phe Asp Glu Gln Thr Arg Arg Leu Lys 275 280 285 Glu Asn Met Gly Thr Leu Glu Thr Trp Ala Asp Lys Thr Gly Lys Ala 290 295 300 Phe Lys Ser Met Trp Asp Ala Ile Leu Asp Ile Gly Arg Pro Glu Ser 305 310 315 320 Ser Ala Asp Met Leu Ala Ser Ala Gln Lys Ala Phe Asp Glu Ala Asp 325 330 335 Lys Lys Trp Gln Trp Tyr Gln Ser Arg Ser Gln Arg Arg Gly Lys Thr 340 345 350 Ala Ser Phe Arg Ala Asn Leu Gln Gly Ala Trp Asn Asp Arg Glu Asn 355 360 365 Ala Arg Leu Gly Leu Ala Ala Ala Thr Leu Gln Ser Asp Met Glu Lys 370 375 380 Ala Gly Glu Leu Ala Ala Arg Asp Arg Ala Glu Arg Asp Ala Ser Gln 385 390 395 400 Leu Lys Tyr Thr Gly Glu Ala Gln Lys Ala Tyr Glu Arg Leu Leu Thr 405 410 415 Pro Leu Glu Lys Tyr Thr Ala Arg Gln Glu Glu Leu Asn Lys Ala Leu 420 425 430 Lys Asp Gly Lys Ile Leu Arg Ala Asp Tyr Asn Thr Leu Met Ala Ala 435 440 445 Ala Lys Lys Asp Tyr Glu Ser Thr Leu Lys Lys Pro Lys Ser Ser Gly 450 455 460 Val Lys Val Ser Ala Gly Glu Arg Gln Glu Asp Gln Ala His Ala Ala 465 470 475 480 Leu Leu Ala Leu Glu Thr Glu Leu Arg Thr Leu Glu Lys His Ser Gly 485 490 495 Ala Asn Glu Lys Ile Ser Gln Gln Arg Arg Asp Leu Trp Lys Ala Glu 500 505 510 Asn Gln Tyr Ala Val Leu Lys Glu Ala Ala Thr Lys Arg Gln Leu Ser 515 520 525 Glu Gln Glu Lys Phe Leu Leu Ala His Lys Asp Glu Thr Leu Glu Tyr 530 535 540 Lys Arg Gln Leu Ala Glu Leu Gly Asp Lys Val Glu His Gln Lys Arg 545 550 555 560 Leu Asn Glu Leu Ala Gln Gln Ala Val Arg Phe Glu Gln Gln Gln Gly 565 570 575 Ala Lys Gln Ala Ala Ile Ser Ala Gln Ala Arg Ala Ser Pro Thr Val 580 585 590 Arg Arg Ser Gly Ser Arg Lys Ser Ser Ala Phe Val Thr Cys Thr Val 595 600 605 Ile Ile Arg Met Arg Trp Arg Arg Pro His Leu His * 610 615 620 <210> 769 <211> 102 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13631..13936) <400> 769 Met His Phe Ser Gly Leu Thr Tyr Ala Val Leu Ser Leu Phe Phe Cys 1 5 10 15 Asp Pro Asp Met His Pro Ser Asp Phe Ser Leu Leu Val Pro Arg His 20 25 30 Glu Glu Glu Gln Val Glu Arg Pro Asp Glu Asp Lys Met Leu Met Gln 35 40 45 Lys Ala Ala Gly Leu Ala Gly Gly Val Arg Phe Gly Gly Asp Gly Gly 50 55 60 Arg Asp Ile Leu Ser Ser Ala Asp Val Ala Asp Val Met Val Asp Asp 65 70 75 80 Ala Ala Leu Met Met Ala Ser Ala Gly Ile Pro Gly Gly Val Arg Tyr 85 90 95 Val Pro Ala Gly Trp * 100 <210> 770 <211> 144 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14071..14502) <400> 770 Met Phe Leu Lys Thr Glu Gln Phe Glu Tyr Asn Gly Val Ser Val Thr 1 5 10 15 Leu Ser Glu Leu Ser Ala Leu Gln Arg Ile Glu His Leu Ala Leu Leu 20 25 30 Lys Arg Arg Ala Glu Gln Ala Glu Ser Ser Gly Asn Leu Gln Val Ser 35 40 45 Val Glu Asp Leu Val Arg Thr Gly Ala Phe Leu Val Ala Met Ser Leu 50 55 60 Trp His Asn His Pro Gln Lys Thr Gln Ser Pro Ser Met Asn Glu Ala 65 70 75 80 Val Met Lys Ile Glu Gln Glu Val Leu Thr Thr Trp Pro Ala Asp Ala 85 90 95 Ile Ala Arg Ala Glu Asp Val Val Leu Cys Leu Ser Gly Met Ser Gly 100 105 110 Ala Val Arg Pro Asp Thr Asp Ile Thr Glu Val Ala Lys Asn Asn Thr 115 120 125 Leu Thr Asp Asp Asp Phe Ser Ala Gly Lys Ser Ser Thr Ala Ser * 130 135 140 <210> 771 <211> 202 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14516..15121) <400> 771 Met Thr Ala Glu Ser Tyr Asp Asp Asn Tyr Leu Asp Asp Glu Asp Ala 1 5 10 15 Asp Trp Thr Ala Thr Gly Gln Gly Gln Lys Ser Ala Gly Asp Thr Ser 20 25 30 Phe Thr Leu Ala Trp Lys Pro Gly Glu Glu Gly Gln Lys Gly Leu Ile 35 40 45 Gly Trp Phe Glu Ser Gly Asp Val Arg Ala Tyr Lys Ile Arg Phe Pro 50 55 60 Asn Gly Thr Val Asp Val Phe Arg Gly Trp Val Ser Ser Ile Gly Lys 65 70 75 80 Ala Val Thr Ala Lys Glu Val Ile Thr Arg Thr Val Lys Val Thr Asn 85 90 95 Val Gly Lys Pro Ser Val Ala Glu Glu Arg Ser Lys Ile Thr Pro Val 100 105 110 Ser Ala Ile Lys Val Thr Pro Thr Ser Gly Thr Val Ala Lys Gly Lys 115 120 125 Thr Thr Thr Leu Thr Val Ser Phe Glu Pro Glu Ser Ala Thr Asp Lys 130 135 140 Thr Phe Arg Ala Val Ser Ala Asp Pro Ser Lys Ala Thr Ile Ser Val 145 150 155 160 Lys Asp Met Thr Ile Thr Val Asn Gly Val Ala Thr Gly Lys Val Gln 165 170 175 Ile Pro Val Val Ser Gly Asn Gly Gln Phe Ala Ala Val Ala Glu Val 180 185 190 Thr Val Thr Glu Ala Gly Ala Ala Gly * 195 200 <210> 772 <211> 89 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15238..15504) <400> 772 Met Gly Leu Phe Thr Thr Arg Gln Leu Leu Gly Tyr Thr Glu Gln Lys 1 5 10 15 Val Lys Phe Arg Ala Leu Phe Leu Glu Leu Phe Phe Arg Arg Thr Val 20 25 30 Asn Phe His Thr Glu Glu Val Met Leu Asp Lys Ile Thr Gly Lys Thr 35 40 45 Pro Val Ala Ala Tyr Val Ser Pro Val Val Glu Gly Lys Val Leu Arg 50 55 60 His Arg Gly Gly Glu Thr Arg Val Leu Arg Pro Gly Tyr Val Lys Pro 65 70 75 80 Lys His Glu Phe Pro Trp Ser Arg * 85 <210> 773 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15562..15909) <400> 773 Met Val Thr Lys Asn Ile Thr Glu Gln Arg Ala Glu Val Arg Ile Phe 1 5 10 15 Ala Gly Asn Asp Pro Ala His Thr Ala Thr Gly Ser Ser Gly Ile Ser 20 25 30 Ser Ala Thr Pro Ala Leu Thr Pro Leu Met Leu Asp Glu Ala Ser Gly 35 40 45 Lys Leu Val Val Trp Asp Gly Gln Lys Ala Gly Ser Ala Val Gly Ile 50 55 60 Leu Val Leu Pro Leu Glu Gly Thr Glu Thr Val Leu Thr Tyr Tyr Lys 65 70 75 80 Ser Gly Thr Phe Ala Thr Glu Ala Ile Arg Trp Pro Glu Ser Val Asp 85 90 95 Glu His Lys Lys Ala Asn Ala Phe Ala Gly Ser Ala Leu Ser His Ala 100 105 110 Ala Leu Pro * 115 <210> 774 <211> 502 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15946..17451) <400> 774 Val Arg Arg Asn Leu Ser His Ile Ile Ala Ala Ala Phe Asn Glu Pro 1 5 10 15 Leu Leu Leu Glu Pro Ala Tyr Ala Arg Val Phe Phe Cys Ala Leu Gly 20 25 30 Arg Glu Met Gly Ala Ala Ser Leu Ser Val Pro Gln Gln Gln Val Gln 35 40 45 Leu Asp Ala Pro Gly Met Leu Ala Glu Thr Asp Glu Tyr Met Ala Gly 50 55 60 Gly Lys Arg Pro Ala Arg Val Tyr Arg Val Val Asn Gly Ile Ala Val 65 70 75 80 Leu Pro Val Thr Gly Thr Leu Val His Arg Leu Gly Gly Met Arg Pro 85 90 95 Phe Ser Gly Met Thr Gly Tyr Asp Gly Ile Val Ala Cys Leu Gln Gln 100 105 110 Ala Met Ala Asp Ser Gln Val Arg Gly Val Leu Leu Asp Ile Asp Ser 115 120 125 Pro Gly Gly Gln Ala Ala Gly Ala Phe Asp Cys Ala Asp Met Ile Tyr 130 135 140 Arg Leu Arg Gln Gln Lys Pro Val Trp Ala Leu Cys Asn Asp Thr Ala 145 150 155 160 Cys Ser Ala Ala Met Leu Leu Ala Ser Ala Cys Ser Arg Arg Leu Val 165 170 175 Thr Gln Thr Ser Arg Ile Gly Ser Ile Gly Val Met Met Ser His Val 180 185 190 Ser Tyr Ala Gly His Leu Ala Gln Ala Gly Val Asp Ile Thr Leu Ile 195 200 205 Tyr Ser Gly Ala His Lys Val Asp Gly Asn Gln Phe Glu Ala Leu Pro 210 215 220 Ala Glu Val Arg Gln Asn Met Gln Gln Arg Ile Asp Ala Ala Arg Arg 225 230 235 240 Met Phe Ala Glu Lys Val Ala Met Phe Thr Gly Leu Ser Val Asp Ala 245 250 255 Val Thr Gly Thr Glu Ala Ala Val Phe Glu Gly Gln Ser Gly Ile Asp 260 265 270 Ala Gly Leu Ala Asp Glu Leu Val Asn Ala Ser Asp Ala Ile Ser Val 275 280 285 Met Ala Thr Ala Leu Asn Ser Asn Val Arg Gly Gly Thr Met Pro Gln 290 295 300 Leu Thr Ala Thr Glu Ala Ala Ala Gln Glu Asn Gln Arg Val Met Gly 305 310 315 320 Ile Leu Thr Cys Gln Glu Ala Lys Gly Arg Glu Gln Leu Ala Thr Met 325 330 335 Leu Ala Gly Gln Gln Gly Met Ser Val Glu Gln Ala Arg Ala Ile Leu 340 345 350 Ala Ala Ala Ala Pro Gln Gln Pro Val Ala Ser Thr Gln Ser Glu Ala 355 360 365 Asp Arg Ile Met Ala Cys Glu Glu Ala Asn Gly Arg Glu Gln Leu Ala 370 375 380 Ala Thr Leu Ala Ala Met Pro Glu Met Thr Val Glu Lys Ala Arg Pro 385 390 395 400 Ile Leu Ala Ala Ser Pro Gln Ala Asp Ala Gly Pro Ser Leu Arg Asp 405 410 415 Gln Ile Met Ala Leu Asp Glu Ala Lys Gly Ala Glu Ala Gln Ala Glu 420 425 430 Gln Leu Ala Ala Cys Pro Gly Met Thr Val Glu Ser Ala Arg Ala Val 435 440 445 Leu Ala Ala Gly Ser Gly Lys Ala Glu Pro Val Ser Ala Ser Thr Thr 450 455 460 Ala Leu Phe Glu Arg Ile Met Ala Asn His Ser Pro Ala Ala Val Gln 465 470 475 480 Gly Gly Val Pro Gln Thr Ser Ala Asp Gly Asp Ala Asp Val Lys Met 485 490 495 Leu Met Ala Met Pro * 500 <210> 775 <211> 531 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17441..19033) <400> 775 Met Lys Arg Thr Pro Val Leu Ile Asp Val Asn Gly Val Pro Leu Arg 1 5 10 15 Glu Ser Leu Ser Tyr Asn Gly Gly Gly Ala Gly Phe Gly Gly Gln Met 20 25 30 Ala Glu Trp Leu Pro Pro Ala Gln Ser Ala Asp Ala Ala Leu Leu Pro 35 40 45 Ala Leu Arg Leu Gly Asn Ala Arg Ala Asp Asp Leu Val Arg Asn Asn 50 55 60 Gly Ile Ala Ala Asn Ala Val Ala Leu His Lys Asp His Ile Val Gly 65 70 75 80 His Met Phe Leu Ile Ser Tyr Arg Pro Asn Trp Arg Trp Leu Gly Met 85 90 95 Arg Glu Thr Ala Ala Lys Ser Phe Val Asp Glu Val Glu Ala Ala Trp 100 105 110 Ser Glu Tyr Ala Glu Gly Met Ser Gly Glu Ile Asp Val Glu Gly Lys 115 120 125 Arg Thr Phe Thr Glu Phe Ile Arg Glu Gly Val Gly Val His Ala Phe 130 135 140 Asn Gly Glu Ile Phe Val Gln Pro Val Trp Asp Thr Glu Thr Thr Gln 145 150 155 160 Leu Phe Arg Thr Arg Phe Lys Ala Val Ser Pro Lys Arg Val Asp Thr 165 170 175 Pro Gly His Gly Met Gly Asn Arg Phe Leu Arg Ala Gly Val Glu Val 180 185 190 Asp Arg Tyr Gly Arg Ala Val Ala Tyr His Ile Cys Glu Asp Asp Phe 195 200 205 Pro Arg Ser Gly Ser Gly Arg Trp Glu Arg Ile Pro Arg Glu Leu Pro 210 215 220 Thr Gly Arg Pro Ala Met Leu His Ile Phe Glu Pro Val Glu Asp Gly 225 230 235 240 Gln Thr Arg Gly Ala Asn Gln Phe Tyr Ser Val Met Glu Arg Leu Lys 245 250 255 Met Leu Asp Ser Leu Gln Ala Thr Gln Leu Gln Ser Ala Ile Val Lys 260 265 270 Ala Met Tyr Ala Ala Thr Ile Glu Ser Asp Leu Asp Thr Glu Lys Ala 275 280 285 Phe Glu Tyr Ile Ala Gly Ala Pro Gln Gly Gln Lys Asp Asn Pro Leu 290 295 300 Ile Asn Ile Leu Glu Lys Phe Ser Ser Trp Tyr Asp Thr Asn Asn Val 305 310 315 320 Thr Leu Gly Gly Val Lys Ile Pro His Leu Phe Pro Gly Asp Asp Leu 325 330 335 Lys Leu Gln Thr Ala Gln Asp Ser Asp Asn Gly Phe Ser Ala Leu Glu 340 345 350 Gln Ala Leu Leu Arg Tyr Ile Ala Ala Gly Leu Gly Val Ser Tyr Glu 355 360 365 Gln Leu Ser Arg Asp Tyr Ser Lys Val Ser Tyr Ser Ser Ala Arg Ala 370 375 380 Ser Ala Asn Glu Ser Trp Arg Tyr Phe Met Gly Arg Arg Lys Phe Ile 385 390 395 400 Ala Ala Arg Leu Ala Thr Gln Met Phe Ser Tyr Trp Leu Glu Glu Ala 405 410 415 Leu Leu Arg Gly Ile Ile Arg Pro Pro Arg Ala Arg Phe Asp Phe Tyr 420 425 430 Gln Ala Arg Ser Ala Trp Ser Arg Ala Glu Trp Ile Gly Ala Gly Arg 435 440 445 Met Ala Ile Asp Gly Leu Lys Glu Val Gln Glu Ser Val Met Arg Ile 450 455 460 Glu Ala Gly Leu Ser Thr Tyr Glu Lys Glu Pro Ala Leu Met Gly Glu 465 470 475 480 Asp Tyr Gln Asp Ile Phe Arg Gln Gln Val Arg Glu Ser Ala Glu Arg 485 490 495 Gln Lys Ala Gly Leu Ser Arg Pro Val Trp Ile Ala Gln Ala Tyr Gln 500 505 510 Gln Gln Ile Ala Glu Ser Arg Arg Pro Glu Glu Glu Thr Thr Pro Arg 515 520 525 Glu Thr * 530 <210> 776 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19030..19236) <400> 776 Met Val Thr Val Ala Glu Leu Gln Ala Leu Arg Gln Ala Arg Leu Asp 1 5 10 15 Leu Leu Thr Gly Lys Arg Val Val Ser Val Gln Lys Asp Gly Arg Arg 20 25 30 Ile Glu Tyr Thr Ala Ala Ser Leu Asp Glu Leu Asn Arg Ala Ile Asn 35 40 45 Asp Ala Glu Ser Val Leu Gly Thr Thr Arg Arg Arg Arg Arg Pro Leu 50 55 60 Gly Val Arg Leu * 65 <210> 777 <211> 643 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19220..21148) <400> 777 Met Asn Ile Ser Glu Gln Gln Leu Asn Asn Met Met Ser Ala Val Thr 1 5 10 15 Thr Ala Leu Gln Pro Leu Ile Arg Ala Leu Pro Val Thr Pro Val Glu 20 25 30 Trp Ala Asp Gln Asn Tyr Tyr Leu Pro Lys Glu Ser Ser Tyr Gly Glu 35 40 45 Gly Glu Trp Lys Thr Leu Pro Phe Gln Ile Ala Ile Met Asn Ser Met 50 55 60 Gly Asn Asp Gln Ile Arg Thr Val Asn Leu Ile Lys Ser Ala Arg Val 65 70 75 80 Gly Tyr Thr Lys Met Leu Leu Gly Gly Gly Gly Tyr Phe Ile Glu His 85 90 95 Lys Ser Arg Asn Ser Leu Leu Phe Gln Pro Thr Asp Ser Ala Ala Glu 100 105 110 Asp Phe Met Lys Ser His Val Glu Ala Thr Ile Arg Asn Val Pro Cys 115 120 125 Leu Lys Asp Leu Ser Pro Trp Leu Gly Arg Lys His Arg Asp Asn Thr 130 135 140 Leu Thr Leu Lys Arg Phe Ser Ser Gly Val Gly Phe Trp Cys Leu Gly 145 150 155 160 Gly Ala Ala Ala Lys Asn Tyr Arg Glu Lys Ser Val Asp Val Val Cys 165 170 175 Tyr Asp Glu Leu Ser Ser Phe Glu Pro Asp Val Glu Lys Glu Gly Ser 180 185 190 Pro Thr Leu Leu Gly Asp Lys Arg Ile Glu Gly Ser Val Trp Pro Lys 195 200 205 Ser Ile Arg Gly Ser Thr Pro Lys Ile Lys Gly Thr Cys Gln Ile Glu 210 215 220 Lys Ala Ala Asn Glu Ser Ala His Phe Met Arg Phe Tyr Val Pro Cys 225 230 235 240 Pro His Cys Gly Glu Ala Gln Tyr Leu Lys Phe Gly Asp Glu Ser Thr 245 250 255 Pro Phe Gly Leu Lys Trp Glu Lys Asp Ser Pro Glu Ser Val Phe Tyr 260 265 270 Leu Cys Glu His His Gly Cys Val Ile His Gln Ser Glu Leu Asp Gln 275 280 285 Ser Asn Gly Arg Trp Ile Cys Glu Asn Thr Gly Met Trp Thr Arg Asp 290 295 300 Gly Leu Thr Phe Phe Ser Ala Arg Gly Asp Glu Ile Pro Pro Pro Arg 305 310 315 320 Ser Ile Met Phe His Ile Trp Thr Ala Tyr Ser Pro Phe Thr Thr Trp 325 330 335 Val Gln Ile Val Tyr Asp Trp Leu Asp Ala Leu Lys Asp Pro Asn Gly 340 345 350 Leu Lys Thr Phe Val Asn Thr Thr Leu Gly Glu Thr Trp Glu Glu Ala 355 360 365 Val Gly Glu Lys Leu Asp His Gln Val Leu Met Asp Lys Val Val Arg 370 375 380 Tyr Thr Ala Ala Val Pro Ala Arg Val Val Tyr Leu Thr Ala Gly Ile 385 390 395 400 Asp Ser Gln Arg Asn Arg Phe Glu Met Tyr Val Trp Gly Trp Ala Pro 405 410 415 Gly Glu Glu Ala Phe Leu Val Asp Lys Ile Ile Ile Met Gly Arg Pro 420 425 430 Asp Glu Glu Glu Thr Leu Leu Arg Val Asp Ala Ala Ile Asn Lys Lys 435 440 445 Tyr Arg His Ala Asp Gly Thr Glu Met Thr Ile Ser Arg Val Cys Trp 450 455 460 Asp Thr Gly Gly Ile Asp Gly Glu Ile Val Tyr Gln Arg Ser Lys Lys 465 470 475 480 His Gly Val Phe Arg Val Leu Pro Val Lys Gly Ala Ser Val Tyr Gly 485 490 495 Lys Pro Val Ile Thr Met Pro Lys Thr Arg Asn Gln Arg Gly Val Tyr 500 505 510 Leu Cys Glu Val Gly Thr Asp Thr Ala Lys Glu Ile Leu Tyr Ala Arg 515 520 525 Met Lys Ala Asp Pro Ser Pro Ala Asp Glu Ala Thr Ser Tyr Ala Ile 530 535 540 Arg Phe Pro Asp Asp Pro Glu Ile Phe Ser Gln Thr Glu Ala Gln Gln 545 550 555 560 Leu Val Ala Glu Glu Leu Val Glu Lys Trp Glu Lys Gly Lys Met Arg 565 570 575 Leu Leu Trp Asp Asn Lys Lys Arg Arg Asn Glu Ala Leu Asp Cys Leu 580 585 590 Val Tyr Ala Tyr Ala Ala Leu Arg Val Ser Val Gln Arg Trp Gln Leu 595 600 605 Asp Leu Ala Val Leu Ala Lys Ser Arg Glu Glu Glu Thr Thr Arg Pro 610 615 620 Thr Leu Lys Glu Leu Ala Ala Lys Leu Ser Gly Gly Val Asn Gly Tyr 625 630 635 640 Ser Arg * <210> 778 <211> 170 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21120..21629) <400> 778 Val Ala Thr Gln Thr Glu Val Ala Arg His Leu Ser Leu Thr Asp Arg 1 5 10 15 Gln Leu Arg Arg Leu Gln Lys Leu Pro Gly Ala Pro Ile Ser Asn Lys 20 25 30 Arg Gly Gln Leu Asp Leu Asp Ala Trp Arg Asp Phe Tyr Ile Ser Tyr 35 40 45 Leu Arg Arg Ser Lys Asn Asp Val Pro Asp Gly Asp Ser Glu Asp Asp 50 55 60 Tyr Glu Glu Lys Leu Leu Ile Ala Arg Trp Glu Leu Thr Ala Glu Gln 65 70 75 80 Ala Val Thr Gln Gln Leu Lys Asn Glu Val Ser Lys Gly Lys Leu Ile 85 90 95 Asp Thr Gly Phe Cys Ile Phe Ala Leu Ser Lys Leu Ala Met Ala Leu 100 105 110 Ser Ser Thr Leu Asp Ser Ile Pro Leu Ser Met Gln Arg Gln Phe Pro 115 120 125 Asp Leu Thr Pro Arg His Leu Asp His Leu Lys Thr Leu Ile Ala Lys 130 135 140 Gly Ala Asn Gln Cys Ala Arg Ala Gly Asp Lys Leu Pro Asp Leu Leu 145 150 155 160 Asp Glu Tyr Ile Arg Ala Thr Thr Glu * 165 <210> 779 <211> 105 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22330..22644) <400> 779 Met Leu His Asp His Leu Ala Glu Cys Leu Glu Lys Lys Gly Leu Tyr 1 5 10 15 Arg Arg Ala Ala Glu Arg Trp Ala Lys Val Met Val Gln Leu Ser Asp 20 25 30 Asp Gln Lys Arg Lys Val Ala Ala Gln Lys Arg Ala Glu Cys Leu Arg 35 40 45 Lys Ala Arg Arg Thr Pro Val Ser Pro Met Asn Leu Thr Glu Ile Lys 50 55 60 Gln Ala Val Asn Arg Leu His Ser Glu Leu Gly Met Gly Phe Glu Glu 65 70 75 80 Arg Arg Val Phe Arg Arg Tyr Lys Gly Thr Gly Glu Gln Asn Thr Ser 85 90 95 Gly Asn Ala Arg Ser Lys Lys Cys * 100 <210> 780 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23171..23356) <400> 780 Met Arg Glu Leu Lys Met Lys Leu Cys Val Leu Met Leu Pro Leu Val 1 5 10 15 Val Ser Ala Cys Ala Ser Thr Pro Thr Val Gln Ala Pro Cys Val Lys 20 25 30 Pro Pro Ser Pro Pro Ala Trp Ile Met Gln Pro Val Pro Asp Trp Gln 35 40 45 Lys Pro Leu Asn Gly Ile Ile Ser Ser Ser Glu Asn Gly * 50 55 60 <210> 781 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23109..23576) <400> 781 Met Asn Arg Val Leu Cys Val Val Ile Ile Val Leu Leu Val Ala Cys 1 5 10 15 Gly Val Leu Ser Leu Gly Leu Asn His Tyr Arg Asp Asn Ala Ile Thr 20 25 30 Tyr Lys Ala Gln Arg Asp Lys Lys Ala Ser Glu Leu Lys Leu Ala Asn 35 40 45 Val Thr Ile Thr Asp Met Gln Val Arg Gln Arg Asp Val Ala Ala Leu 50 55 60 Asp Ala Arg Tyr Ser Arg Glu Leu Ala Asp Ala Arg Ala Glu Asn Glu 65 70 75 80 Thr Leu Arg Ala Asp Val Ala Ala Gly Arg Lys Arg Leu Arg Ile Asn 85 90 95 Ala Asn Cys Pro Gly Ser Leu Arg Lys Ala Pro Ile Thr Ser Gly Val 100 105 110 Asp Asn Ala Thr Gly Pro Arg Leu Ala Glu Ala Ala Glu Arg Asp Tyr 115 120 125 Phe Ile Leu Arg Glu Arg Leu Met Ala Met Gln Lys Gln Leu Glu Gly 130 135 140 Ala Gln Glu Tyr Ile Arg Thr Gln Cys Ile Pro * 145 150 155 <210> 782 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23728..23910) <400> 782 Met Gly Lys Tyr Lys Arg Ile Leu Leu Arg Leu Thr Met Lys Asn Gly 1 5 10 15 Leu Glu Leu Lys Ala Pro Val Thr Asp Asp Val Ser Arg Ala Leu Ala 20 25 30 Phe Ala Ile Lys Trp Val Ala Val Gly Ile Ala Val Ser Pro Met Leu 35 40 45 Tyr Gly Leu Ala Lys Leu Val Ile Ala Leu Lys Ser * 50 55 60 <210> 783 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24066..24599) <400> 783 Met Asn Ala Lys Ile Arg Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Gly Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Ile Leu Val Asp Gly Lys Pro Val Val 50 55 60 Pro Gly Met Lys Leu Ser Lys Glu Lys Cys Asp Gln Val Asn Ala Ile 65 70 75 80 Glu Arg Asp Lys Ala Leu Glu Trp Val Glu Arg Asn Ile Lys Val Pro 85 90 95 Leu Thr Glu Pro Gln Lys Ala Gly Ile Ala Ser Phe Cys Pro Tyr Asn 100 105 110 Ile Gly Pro Gly Lys Cys Phe Pro Ser Thr Phe Tyr Arg Arg Ile Asn 115 120 125 Ala Gly Asp Arg Arg Gly Ala Cys Glu Ala Ile Arg Trp Trp Ile Lys 130 135 140 Asp Gly Gly Arg Asp Cys Arg Ile Arg Ser Asn Asn Cys Tyr Gly Gln 145 150 155 160 Val Ser Arg Arg Asp Gln Glu Ser Ala Leu Ala Cys Trp Gly Ile Asp 165 170 175 Arg * <210> 784 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24650..24994) <400> 784 Met Lys Lys Lys Tyr Glu Leu Gly Val Lys Gly Ile Asn Asn Tyr Pro 1 5 10 15 Asp Lys Ile Thr Val Thr Val Ala Pro Glu Ile Gly Gly Tyr Pro Ser 20 25 30 Leu Leu Leu Pro Asp Val Ala Ile Ser Leu Asp Arg Thr Glu Gly Ala 35 40 45 Thr Leu Glu Phe Tyr Glu Ala Glu Ala Lys Lys Gln Ala Lys Gln Phe 50 55 60 Phe Met Asp Val Ala Ala Gly Leu Cys Glu Gly Asp Gly Pro Leu Pro 65 70 75 80 Glu Lys Arg Pro Val Ile Leu Glu Ala Gln Asp Val Leu Ile Thr Tyr 85 90 95 Arg Gly Lys Leu Pro Gly Ile Ile Thr Gly Ser Leu Lys Thr Pro Pro 100 105 110 Leu Ala * <210> 785 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24999..25205) <400> 785 Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser Ala Val Gly 1 5 10 15 Thr Gly Tyr Trp Leu Leu Gln Leu Leu Asp Lys Val Ser Pro Ser Gln 20 25 30 Trp Val Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly Leu Leu Thr 35 40 45 Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Arg Glu Asp Arg Arg Lys Ala 50 55 60 Ala Arg Gly Glu * 65 <210> 786 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25525..25851) <400> 786 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 787 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25848..26738) <400> 787 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 788 <211> 617 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26820..28670) <400> 788 Met Ser Ile Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Glu Lys Leu Thr His Lys Leu Lys Glu Gly Trp Gln Pro Tyr 20 25 30 Gly Gly Pro Val Ala Ile Thr Pro Tyr Thr Leu Met Gln Ala Val Ala 35 40 45 Ile Glu Gly Glu Pro Gln Val Gly Pro Ser Ser Glu Pro Asp Trp Tyr 50 55 60 Tyr Val Ile Val Leu Ala Gly Gln Ser Asn Ala Met Ala Tyr Gly Glu 65 70 75 80 Gly Leu Pro Leu Pro Asp Ser Tyr Asp Ala Pro Asp Pro Arg Ile Lys 85 90 95 Gln Leu Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Ala Ala Cys Arg 100 105 110 Tyr Asn Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln Asp 115 120 125 Met Ser Thr Leu Asn His Pro Arg Ala Asp Leu Ser Lys Gly Gln Tyr 130 135 140 Gly Cys Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro Tyr 145 150 155 160 Ile Pro Asn Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly Gly 165 170 175 Ser Ala Phe Thr Gln Gly Ala Glu Gly Thr Phe Ser Glu Ser Thr Gly 180 185 190 Ala Ser Gln Asp Ser Ala Arg Trp Gly Val Gly Lys Pro Leu Tyr Gln 195 200 205 Asp Leu Ile Ser Arg Thr Lys Ala Ala Leu Gln Lys Asn Pro Lys Asn 210 215 220 Val Leu Leu Ala Val Cys Trp Met Gln Gly Glu Phe Asp Met Ser Ala 225 230 235 240 Ala Thr His Ala Gln Gln Pro Ala Leu Phe Thr Ala Met Leu Thr Gln 245 250 255 Phe Arg Ala Asp Leu Ser Val Phe Asn Ala Gln Cys His Gly Gly Ser 260 265 270 Ala Ala Asp Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Tyr Trp Lys 275 280 285 Asn Thr Tyr Ala Thr Gln Tyr Asp Thr Val Tyr Gly Gly Tyr Lys Asn 290 295 300 Arg Glu Ser Glu Gly Val Tyr Phe Val Pro Phe Met Thr Asp Gly Asn 305 310 315 320 Gly Val Asn Thr Ala Thr Asn Ala Pro Ala Glu Asp Pro Asp Ile Pro 325 330 335 Ala Ser Gly Tyr Tyr Gly Ala Ala Ser Arg Thr Asn Gly Asn Gln Val 340 345 350 Ser Ser Asn Arg Pro Thr His Phe Ser Ser Trp Ala Arg Arg Ser Ile 355 360 365 Ile Pro Asp Arg Leu Ala Thr Ala Ile Leu Asn Ala Ala Gly Arg Thr 370 375 380 Ser Ala Phe Ile Ser Gly Lys Ala Pro Glu Ile Lys Pro Ser Pro Gly 385 390 395 400 Gly Asn Thr Pro Ser Gly Pro Ser Ala Asp Thr Ser Val Arg Thr Ile 405 410 415 Ser Leu Leu Pro Ala Ala Gly Glu Ala Ala Ala Gln Gly Trp Ser Ile 420 425 430 Lys Asp Gly Gly Ile Gln Leu Ser Asp Gly Val Phe Lys Ile Thr Arg 435 440 445 Gln Ser Asn Lys Thr Trp Ser Leu Thr His Pro Val Asp Asp Ala Ile 450 455 460 Thr Leu Leu Thr Gln Gly Gly Arg Leu Thr Cys Lys Phe Arg Leu Ser 465 470 475 480 Gly Ala Leu Thr Asn Asn Gln Phe Gly Leu Gly Ile Tyr Leu Tyr Thr 485 490 495 Asp Ala Pro Val Pro Asp Gly Val Ala Met Thr Gly Thr Gly Asn Pro 500 505 510 Phe Leu Met Ser Tyr Phe Thr Gln Thr Thr Asp Gly Arg Val Asn Leu 515 520 525 Met His His Arg Lys Ala Gly Asn Thr Lys Leu Gly Glu Phe Gly Asp 530 535 540 Tyr Gly Asn Asp Trp Gln Thr Leu Glu Leu Val Phe Thr Ala Gly Ser 545 550 555 560 Ala Met Val Thr Pro Lys Leu Asn Gly Val Ala Gly Pro Ala Phe Gln 565 570 575 Val Ile Lys Asp Ser Leu Thr Leu Gly Leu Asn Ala Leu Thr Leu Thr 580 585 590 Asp Val Thr Lys Asn Ala Ala Tyr Gly Val Glu Ile Glu Ser Leu Met 595 600 605 Leu Glu Ile Asn Ala Pro Ala Ala * 610 615 <210> 789 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28719..28883) <400> 789 Val Leu Ile Leu Asn Ser Pro Gly Gly Thr Arg His His Ala Leu Pro 1 5 10 15 Gln Lys Cys Tyr Phe Cys Phe Ser Gln Thr Ile Ile Val Ile Pro Leu 20 25 30 Phe Ser Ala Ala His Gly Ala Ala Phe Phe Tyr Asp Gln Pro Leu Ala 35 40 45 Asp Gly His Pro Val Ile * 50 <210> 790 <211> 56 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28984..29151) <400> 790 Val Thr Val Lys Leu Arg Leu Thr Val Ala Ala Leu Leu Leu Phe Leu 1 5 10 15 Val Val Met Val Asp Phe Thr Ser Arg Ile Met Ser Val Leu Ala Asp 20 25 30 Gly Val Leu Val Cys Gly Ile Met Val Leu Leu Trp Pro Val Ile Lys 35 40 45 Arg Asn Ser Leu His Asn Ala * 50 55 <210> 791 <211> 143 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29148..29576) <400> 791 Leu Val Phe Leu Val Lys Lys Ala Arg Arg Ala Ala Thr Glu Ile Lys 1 5 10 15 Lys Phe Glu Lys Arg Asp Leu Ala Gln Val Val Ile Asn Ala Ala Tyr 20 25 30 Leu Val Ala Cys Ala Asp Gly Glu Cys Glu Ala Ser Glu Lys Ala Lys 35 40 45 Ile Glu Gln Val Leu Arg Asn Gln Pro Ala Leu Tyr Ala Phe Thr Ser 50 55 60 Glu Ile Asn Ala Ile Ser Ala Thr Ile Ile Gly Gln Leu Asp Thr Asn 65 70 75 80 Phe Lys Thr Gly Arg Arg Ala Ala Leu Arg Glu Ile Glu Asp Val Lys 85 90 95 His Asp Thr Arg Glu Ala Glu Asp Val Leu Asp Val Ala Val Ala Ile 100 105 110 Ala Glu Ala Asp Gly Glu Ile Glu Pro Glu Glu Arg Lys Val Leu Glu 115 120 125 Glu Ile Ala Gly Val Leu Gly Leu Arg Leu Glu Asn Tyr Leu * 130 135 140 <210> 792 <211> 230 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30210..30899) <400> 792 Met Asn Asn His Tyr Leu Gln Phe Val Arg Glu Leu Leu Ile Ile Ala 1 5 10 15 Thr Ala Asp Leu Ser Gly Ala Thr Lys Gly Gln Leu Glu Ala Trp Gln 20 25 30 Glu Asn Ala Met Phe Asp Thr Gly Arg Tyr Arg Arg Lys Lys Ile Arg 35 40 45 Tyr Arg Asp Glu Val Thr Gly Lys Met Ile Thr Arg Asp Asn Pro Pro 50 55 60 Ile Pro Gly Lys Gln Ser Leu Ala Lys Val Thr Ser Ile Pro Leu Val 65 70 75 80 Ser Pro Val Glu Phe Ser Thr Ser Ser Trp Arg Arg Ala Val Leu Ser 85 90 95 Leu Glu Glu His His Lys Ala Trp Leu Leu Trp Cys Tyr Ser Gly Ser 100 105 110 Ile Cys Trp Glu Tyr Gln Ile Ala Ile Thr Gln Trp Ala Trp Asn Glu 115 120 125 Phe Asn Thr Gln Ser Gly Thr Arg Lys Ile Ala Gly Lys Thr Gln Glu 130 135 140 Arg Leu Lys Lys Leu Ile Trp Leu Ala Ala Gln Ala Val Lys Ala Glu 145 150 155 160 Leu Phe Gly Gly Glu Gly Tyr Glu Tyr Lys Glu Leu Ala Leu Leu Val 165 170 175 Gly Val Thr Thr Lys Asn Trp Ser Lys Thr Phe Thr Arg His Trp Val 180 185 190 Ala Met Lys His Ile Phe His Arg Leu Asp Ser Glu Ala Leu Leu Phe 195 200 205 Val Met Arg Thr Arg Ser Lys Gln Lys Ala Ala Phe Ser Lys Gln Ser 210 215 220 Val Ala Lys Val Asp * 225 <210> 793 <211> 120 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30896..31255) <400> 793 Met Leu Ile Asp Leu Val Leu Pro Tyr Pro Pro Thr Val Asn Thr Tyr 1 5 10 15 Trp Arg Arg Arg Gly Ser Thr Tyr Phe Val Ser Lys Ala Gly Glu Arg 20 25 30 Tyr Arg Arg Ala Val Ala Leu Ile Val Arg Gln Gln Arg Leu Lys Leu 35 40 45 Ser Leu Ser Gly Arg Leu Ala Ile Lys Ile Ile Ala Glu Pro Pro Asp 50 55 60 Lys Arg Arg Arg Asp Leu Asp Asn Ile Leu Lys Ala Pro Leu Asp Ala 65 70 75 80 Leu Thr His Ala Gly Leu Leu Met Asp Asp Glu Gln Phe Asp Glu Ile 85 90 95 Asn Ile Val Arg Gly Gln Leu Val Pro Gly Glu Arg Leu Gly Ile Lys 100 105 110 Ile Thr Glu Leu Glu Cys Ala * 115 <210> 794 <211> 350 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31268..32317) <400> 794 Val Arg Val Leu Leu Arg Pro Val Leu Val Pro Glu Leu Gly Leu Val 1 5 10 15 Ile Val Lys Pro Gly Arg Glu Ser Met Pro Val Phe His Asn Thr Arg 20 25 30 Val Leu Val Glu Pro Glu Pro Lys Ser Met Arg Asn Leu Pro Ser Gly 35 40 45 Val Val Pro Ala Val Arg Gln Pro Leu Ala Glu Asp Lys Ser Leu Leu 50 55 60 Pro Phe Phe Ser Asp Glu Arg Val Ile Arg Ala Ala Gly Gly Ala Gly 65 70 75 80 Ala Leu Ser Asp Trp Leu Leu Arg His Val Lys Ser Cys Gln Trp Pro 85 90 95 His Gly Asp Tyr His His Ser Glu Thr Val Ile His Arg Tyr Gly Thr 100 105 110 Gly Ala Met Val Leu Cys Trp His Cys Asp Asn Gln Leu Arg Asp Gln 115 120 125 Thr Ser Glu Ser Leu Glu Gln Leu Ala His Gln Asn Leu Ser Ala Trp 130 135 140 Met Ile Asp Val Ile Arg His Ala Met Asn Gly Thr Gln Glu Arg Glu 145 150 155 160 Leu Ser Leu Ala Glu Leu Ser Trp Trp Ala Ala Cys Asn Gln Val Val 165 170 175 Asp Ala Leu Pro Glu Ala Val Ala Arg Arg Ser Leu Gly Leu Pro Ala 180 185 190 Glu Lys Ile Arg Ser Val Tyr Arg Glu Ser Asp Ile Val Pro Gly Glu 195 200 205 Gln Thr Ala Ile Ser Ile Leu Lys Gln Arg Thr Lys Asn Ile Ala Leu 210 215 220 Pro Leu His Val His Gln Gln Gln Asn Pro Pro Gln Lys Lys Thr Val 225 230 235 240 Val Ser Ile Ala Val Asp Pro Glu Ser Pro Glu Ser Phe Met Arg Arg 245 250 255 Pro Lys Arg Cys Arg Trp Val Asn Glu Lys Tyr Thr Arg Trp Val Lys 260 265 270 Thr Gln Pro Cys Ala Cys Cys Gly Lys Pro Ala Asp Asp Pro His His 275 280 285 Leu Ile Gly His Gly Gln Gly Gly Met Gly Thr Lys Ala His Asp Ile 290 295 300 Phe Thr Leu Pro Leu Cys Arg Glu His His Asn Glu Leu His Ala Asp 305 310 315 320 Pro Leu Glu Phe Glu Lys Lys Tyr Gly Ser Gln Ile Glu Leu Ile Phe 325 330 335 Arg Phe Leu Asp His Ala Phe Ala Thr Gly Val Leu Gly * 340 345 <210> 795 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32319..32597) <400> 795 Met Ala His Asp Thr Lys Phe Tyr Asn Ser Asp Asn Ser Ala Ala Pro 1 5 10 15 Ala Ser Arg His Gly Arg Arg Ser His Ala Phe Lys Ser Asp Trp Tyr 20 25 30 Gln His Asp Pro Cys Thr Glu Glu Gln Ala Glu Trp Leu Ile Gln Cys 35 40 45 Tyr Arg Arg Arg Gly Tyr Glu Val Lys Lys Ala Leu Ser Leu Asp Tyr 50 55 60 Arg His Trp Ile Ile Ser Val Arg Leu Pro Tyr Ser Glu Arg Pro Pro 65 70 75 80 Arg Pro Ser Arg Thr Phe Gln Gln Arg Ile Trp Arg * 85 90 <210> 796 <211> 71 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32765..32977) <400> 796 Met Leu His Lys Arg Arg Leu Ala Ser Tyr Ala Pro Lys Gly Lys Glu 1 5 10 15 Lys Gln Val Met Lys Gln Gln Lys Ala Met Leu Ile Ala Leu Ile Val 20 25 30 Ile Cys Leu Thr Val Ile Val Thr Ala Leu Val Thr Arg Lys Asp Leu 35 40 45 Cys Glu Val Arg Ile Arg Thr Gly Gln Thr Glu Val Ala Val Phe Thr 50 55 60 Ala Tyr Glu Pro Glu Glu * 65 70 <210> 797 <211> 35 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33164..33268) <400> 797 Met Ser Asp Asp Ile Ser Leu Val Met Glu Gly Ala Leu Ala Val Ile 1 5 10 15 Ala Val Val Gly Val Tyr Cys Leu Val Val Phe Leu Met Glu Arg Leu 20 25 30 Gly Asn * <210> 798 <211> 188 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33378..33941) <400> 798 Met Thr Glu Leu Thr Lys Glu Trp Leu Gln Asn Thr Ile Thr Gly Ile 1 5 10 15 Glu Ser Ser Arg Asp Glu Ile Pro Phe Gly Leu Asp Glu Asp Gln Asn 20 25 30 Asn Met Leu Thr Ala Leu Lys Ile Ala Leu Ala Ser Leu Ala Ser Val 35 40 45 Ser Asp Glu Arg Ala Ala Tyr Glu Leu Phe Met Glu Lys Arg Phe Gly 50 55 60 Glu Ser Val Asp Arg Arg Arg Ala Lys Asn Gly Asp Arg Glu Tyr Met 65 70 75 80 Ala Trp Asp Met Ala Leu Gly Trp Ile Ile Trp Cys His Arg Ala Ala 85 90 95 Met Leu Gln Ala Gly Asn Phe Arg Glu Asn Lys Gly Ser Ser Thr Asn 100 105 110 Asn Phe Arg Ile Ile Ser Glu Thr Ser Thr Asn Ser Pro Ala Ile Pro 115 120 125 Asp Glu Val Leu Ser Ala Ile Leu Lys Val Ala Arg Leu Arg Ala Asp 130 135 140 Phe Asp Ala Ser Glu Val Asp Arg Arg Gly Ile Gly Ser Cys Leu Asp 145 150 155 160 Glu Ala Glu Gln Glu Leu Ile Val Thr Ile Asn Glu Tyr Ala Ser Gln 165 170 175 Ile Ala Val Glu Ala Thr Gln Gly Glu Asn Gln * 180 185 <210> 799 <211> 104 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34068..34379) <400> 799 Met Ser Val Ile Lys Glu Met Pro Val Glu Arg Asn Glu Tyr Gly Cys 1 5 10 15 Trp Thr His Pro Glu Tyr Glu Lys Phe Cys Asp Gly Arg Glu Tyr Ile 20 25 30 Ser Thr Glu Glu Phe Asn Ala Trp Met Glu Lys Asn Asn Leu Gln Trp 35 40 45 Ala Ile Arg Ser Met Asp Glu Asp Asp Phe Asn Leu Asp Ala Asp Gly 50 55 60 Pro Asp Ile Ser Ala Trp Glu Pro Glu Arg Pro Glu Gly Glu Gly Trp 65 70 75 80 Phe Ile Gly Ser Ile His Asp Thr Glu Asp Gly Pro Val Cys Val Trp 85 90 95 Leu Arg Asn Lys Ala Glu Ala * 100 <210> 800 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34376..34564) <400> 800 Val Ser Lys Thr Asn Pro Gly Trp Ala Arg Pro Leu Met Ala Lys Lys 1 5 10 15 His His Tyr Phe Ala Glu Gly Glu Ile Thr Ser Ile Cys Gly Gly Trp 20 25 30 Met Tyr Phe Gly Asn Glu Arg Glu Pro Asp Thr Phe Glu Ser Pro Asp 35 40 45 Asp Cys Lys Lys Cys Arg Arg Lys Leu Asn Lys Gly Gly Lys * 50 55 60 <210> 801 <211> 119 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34561..34917) <400> 801 Met Ser Glu Ile Asn Tyr Gln Glu Leu Arg Val Glu Leu Gly Ala Ala 1 5 10 15 Lys Lys Arg Ile Glu Glu Leu Glu Ala Asn Arg Val Val Leu Glu Val 20 25 30 Glu Asn Glu Arg Leu Lys His Ala Met Ala Val Ala Leu Glu His Ile 35 40 45 Ser Val Thr Asp Ala Gly Gln Ala Gly Val Ala Ala Met Ile Ile Tyr 50 55 60 Asp Ala Met Tyr His Ser Glu Lys Thr Asp Pro Tyr Ala Phe Leu Ala 65 70 75 80 Glu Leu Arg Ala Gln Gly Val Glu Met Val Arg Glu His Pro Ala Ile 85 90 95 Lys Leu Cys Ser Leu Thr His Ile Cys Asp Glu Leu Val Ala Glu Leu 100 105 110 Arg Lys Gly Gly Asn Lys * 115 <210> 802 <211> 75 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34914..35138) <400> 802 Met Lys Ile Arg Tyr His Asp Phe Gly Pro Val Ser His Met Leu Ile 1 5 10 15 Ser Ser Thr Val Leu Glu Thr Arg Lys His Asn His Ile Leu Asp Met 20 25 30 Leu Arg Leu Ala Asp Pro Tyr Leu Val Ile Asn Thr Ser Gly Ile Phe 35 40 45 Phe Leu Arg Ser Thr Val Ser Gly Lys Thr Ser His Val Leu Arg Ala 50 55 60 Tyr Lys Thr Ala Val Arg Glu Glu Gly Glu * 65 70 <210> 803 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35160..35858) <400> 803 Met Glu Thr Val Phe Asp Ala Leu Lys Ala Leu Lys Lys Ala Ser Ser 1 5 10 15 His Glu Ile Ala Ala Arg Leu Glu Ile Ser Arg Asp Asp Ala Val Thr 20 25 30 Glu Leu Trp Lys Leu Lys Arg Arg Gly Glu Ala Asp Asn Lys Gly Ser 35 40 45 Met Trp Trp Leu Thr Ser Glu Ala Thr Glu Ala Ala Pro Lys Thr Thr 50 55 60 Ala Glu Met Leu Ile Asn Ala Ile Glu Gln His Gly Pro Gln Ser Ala 65 70 75 80 Asp Glu Leu Ala Leu Met Phe Gly Ile Thr Ser Arg Arg Ala Asn Ser 85 90 95 Ser Leu Ala Met Ala Val Ser Lys Gly Arg Leu Ile Arg Val Asn Gln 100 105 110 Asp Gly Lys Tyr Arg Tyr Cys Ile Pro Gly Asp Asn Leu Pro Ala Glu 115 120 125 Pro Lys Ala Ala Ser Val Thr Glu Thr Asp Gly Lys Ala Phe Pro Gln 130 135 140 Pro Ala Gly Val Ala Leu Pro Val Arg Glu Ala Glu Thr Gln Glu Glu 145 150 155 160 Ile Lys Thr Glu Ser Val Ala Val Thr Val Gln Ser Gln Ser Ser Phe 165 170 175 Ile Arg Lys His Pro Asp Gly Leu Ile Leu Pro Ser Leu His Val Ala 180 185 190 Asn Arg Glu Leu Arg Arg Ala Lys Gly Gln Val Gln Lys Trp Glu Arg 195 200 205 Leu Cys Ala Ala Leu Arg Glu Ile Asn Lys His Arg Asp Val Ile Gln 210 215 220 Lys Ile Thr Thr Gly Asp Asn Gly * 225 230 <210> 804 <211> 221 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35893..36555) <400> 804 Met Gln His Gln Val Ala Pro His His Gly Gln Phe Arg Lys Phe Gly 1 5 10 15 Gln His Val Asn Ser Gly Asn Val Lys Thr Asp Leu Ser Ala Thr Glu 20 25 30 Thr Ala Trp Lys Leu Trp Glu Leu Met Gly Glu Val Tyr Ser Asn Arg 35 40 45 Trp Thr Gln Lys Asn Gly Ala Ala Pro Ser Lys Leu Trp Ile Ala Gln 50 55 60 Ile Gly Ala Met Thr Glu Gln Gln Ile Arg Gln Val Cys Arg Gln Cys 65 70 75 80 Met Asp Arg Cys Arg Ala Gly Glu Thr Trp Pro Pro Asp Leu Ala Glu 85 90 95 Phe Val Ala Leu Ile Ser Glu Ser Gly Ala Asn Pro Phe Gly Leu Thr 100 105 110 Val Asp Ala Val Met Glu Glu Tyr Arg Arg Trp Arg Asn Glu Ser Trp 115 120 125 Arg Tyr Asp Gly Ser Asp Lys Tyr Pro Trp Pro Gln Pro Val Leu Tyr 130 135 140 His Ile Cys Leu Glu Met Arg Ser Lys Gly Ile Glu Arg Gln Met Thr 145 150 155 160 Glu Gly Glu Leu Lys Arg Leu Val Glu Arg Gln Leu Thr Lys Trp Ala 165 170 175 Lys His Val Gly Asn Gly Leu Ser Val Pro Pro Val Arg Arg Gln Leu 180 185 190 Ala Ala Pro Lys Arg Pro Pro Gly Pro Thr Pro Ile Glu Leu Leu Lys 195 200 205 Gln Glu Tyr Glu Arg Arg Lys Ala Ala Gly Phe Val * 210 215 220 <210> 805 <211> 346 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36347..37384) <400> 805 Met Ala Asn Ala Trp Leu Arg Leu Trp His Asp Met Pro Asn Asp Pro 1 5 10 15 Lys Trp Arg Thr Ile Ala Arg Val Ser Gly Gln Pro Ile Ala Thr Val 20 25 30 Met Ala Val Tyr Ile His Leu Leu Val Ser Ala Ser Arg Asn Val Thr 35 40 45 Thr Cys His Gly Val Ser Leu Arg Gly His Ile Asp Val Thr Thr Glu 50 55 60 Asp Leu Ala Ser Ala Leu Asp Val Thr Glu Asp Val Ile Asp Ser Ile 65 70 75 80 Leu His Ala Met Gln Gly Arg Val Leu Asp Gly Asp Leu Ile Ser Gly 85 90 95 Trp Glu Lys Arg Gln Val Met Lys Glu Asp Asn Gly Asn Val Ser Gln 100 105 110 Thr Ala Lys Ser Pro Ala Glu Arg Lys Arg Ala Gln Arg Glu Arg Glu 115 120 125 Arg Leu Arg Lys Gln Asn Thr Asp Cys His Asp Glu Ser Arg Arg Val 130 135 140 Thr His Met Ser Arg Gln Ile Thr Thr Asp Thr Asp Thr Asp Lys Glu 145 150 155 160 Leu Asn Pro Thr His Asn Ala Arg Met Arg Glu Ser Ala Thr Thr Gly 165 170 175 Glu Leu Asn Asp Ala Ser Leu Gln Thr Ala Glu Pro Glu Tyr Leu Asp 180 185 190 Gly Leu Ser Glu Pro Ile Gly Lys Phe Pro Met Thr Gly Val Trp Gln 195 200 205 Pro Ser Pro Asp Phe Arg Gln Arg Ala Ala Val Trp Gly Met Ala Leu 210 215 220 Pro Glu Pro Glu Phe Thr Pro Ala Glu Leu Ala Ala Phe Arg Asp Tyr 225 230 235 240 Trp Met Ala Glu Gly Lys Val Phe Thr Gln Val Gln Trp Glu Gln Lys 245 250 255 Phe Ala Arg His Val Gln His Val Arg Ala Gln Val Lys Pro Val Ser 260 265 270 Lys Gly Val Ser His Ala Ala Pro Gly Gly Thr Ala Ser Arg Ala Val 275 280 285 Gln Glu Ile Arg Ala Ala Arg Glu Gln Trp Glu Arg Glu Asn Gly Phe 290 295 300 Ile Ser Asn Gly Asn Gly Leu Glu Ala Val Gly Thr Tyr Gly Gly Gly 305 310 315 320 Val Phe Glu Pro Leu Asp Pro Glu Glu Arg Gly Cys Ala Val Glu Ala 325 330 335 Leu Asp Cys Ser Asp Trp Arg Asp Asp * 340 345 <210> 806 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37453..37878) <400> 806 Met Lys Ile Lys His Glu His Ile Arg Met Ala Ile Asn Ala Trp Ala 1 5 10 15 Tyr Pro Asp Gly Glu Lys Val Pro Ala Ala Glu Ile Ala Arg Thr Tyr 20 25 30 Phe Glu Leu Gly Met Thr Phe Pro Glu Leu Tyr Asp Asp Ser His Pro 35 40 45 Glu Ala Leu Ala Arg Asn Thr Gln Lys Ile Phe Arg Trp Leu Asp Lys 50 55 60 Asp Thr Pro Asp Ala Val Glu Lys Ile Gln Ala Leu Leu Pro Ala Ile 65 70 75 80 Glu Lys Ala Met Pro Pro Leu Leu Val Ala Arg Met Arg Ser His Ser 85 90 95 Ser Glu Tyr Tyr Arg Glu Ile Val Glu Arg Arg Asp Arg Leu Val Lys 100 105 110 Asp Val Asp Asp Phe Val Ala Ala Ala Ile Ala Trp Gly Thr Leu Thr 115 120 125 Asn Ser Gly Gly Gln Pro Gly Asn Ala Val Val Val His * 130 135 140 <210> 807 <211> 76 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37875..38102) <400> 807 Met Arg Val Asp Glu Leu Val Gln Phe Phe Gly Ser Val Gln Arg Val 1 5 10 15 Ala Asp Phe Tyr Gly Ile Thr Arg Glu Ala Ile Tyr Met Trp Arg Lys 20 25 30 Arg Pro Gly Glu Ile Val Pro Lys Gly Arg Ala Ala Glu Ala Ala Ala 35 40 45 Tyr Ser Lys Gly Lys Leu Ser Leu Asn Pro Glu Leu Tyr Lys Lys Lys 50 55 60 Asp Thr Thr Gln Gly Glu Gly Lys Gly Asp Ser * 65 70 75 <210> 808 <211> 216 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38197..38844) <400> 808 Met Met Glu Ser Leu Gly Phe Arg Leu Lys Arg Leu Arg Lys Asp Lys 1 5 10 15 Gly Leu Thr Gln Val Glu Leu Gly Lys Leu Ser Gly Val Thr Gly Val 20 25 30 Thr Ile Gly Tyr Trp Glu Lys Asp Leu Asn Glu Pro Gly Ser Lys Ala 35 40 45 Leu Ser Lys Leu Ala Gln Ala Leu Gly Thr Thr Glu Ser Tyr Leu Leu 50 55 60 Tyr Gly Val Ser Ser Pro Glu Leu Ser Phe Val Gln Ser Thr Ser Gly 65 70 75 80 Thr Lys Ile Pro Tyr Leu Ser Trp Gly Glu Ala Ile Ser Phe Leu Ile 85 90 95 Leu Lys Gly Glu Lys Thr Met Gly Asn Val Asp Arg Ile Thr Thr Phe 100 105 110 Phe Asp Val Glu Glu Gly Asp Phe Ala Val Ser Met Pro Asp Asp Thr 115 120 125 Met His Asn Pro Ser Gly Ser Pro Ser Ile Pro Val Gly Ala Thr Val 130 135 140 Ile Leu Arg Pro Gly Glu Ser Tyr Lys Asn Gly Ser Ile Val Ala Val 145 150 155 160 Ile Val Pro Asp Pro Leu Lys Asn Glu Pro Ser Met Thr Ile Lys Lys 165 170 175 Leu Val Ile Asp Gly Lys Leu Val Tyr Leu Ser Pro Leu Asn Pro Arg 180 185 190 Tyr Gln Ser Ser Leu Leu Thr Pro Glu Cys Lys Ile Val Ala Val Ala 195 200 205 Lys Gly Val Gln Phe Asn Leu * 210 215 <210> 809 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39119..39271) <400> 809 Met Asp Met Leu Asn Leu Gly Asn Asn Glu Ser Leu Val Cys Gly Val 1 5 10 15 Phe Pro Asn His Asp Gly Thr Phe Thr Ala Met Thr Tyr Thr Arg Ser 20 25 30 Lys Thr Phe Lys Thr Glu Ala Gly Ala His Arg Trp Leu Ala Arg Asn 35 40 45 Ala Asn * 50 <210> 810 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39752..39940) <400> 810 Met Glu Thr Leu Leu Pro Asn Val Asn Thr Ser Glu Gly Cys Phe Asp 1 5 10 15 Ile Gly Val Leu Leu Ser Asn Lys Ala Phe Thr Glu Asp Ala Ile Asn 20 25 30 Met Arg Lys Tyr Glu Pro Tyr Leu Leu Asn Asp Asn Ser Ile Leu Ser 35 40 45 Arg Ile Ala Leu Ile Lys Leu Gly Ile Phe Gly Glu Arg Gln * 50 55 60 <210> 811 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39937..40125) <400> 811 Met Thr Ser Ala Phe Ala Leu Val Met Thr Val Phe Leu Ile Thr Gly 1 5 10 15 Glu Ser Gln Asn Val Ile Thr Gly Ile Tyr Ala Ser Lys Glu Ser Cys 20 25 30 Leu Gln Ala Arg Asp Glu Gln Lys Ile Ser Gly Glu Cys Leu Pro Val 35 40 45 Lys Lys Val Ser Leu Tyr Leu Asn Asn Glu Thr Pro Ala Gly * 50 55 60 <210> 812 <211> 733 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40221..42419) <400> 812 Met Ser Lys Ile Phe Ile Cys Ala Ala Ile Pro Asp Glu Gln Ala Ile 1 5 10 15 Lys Glu Asp Ser Ala Val Ala Val Ala Thr Ala Ile Glu Ala Gly Asp 20 25 30 Glu Arg Arg Ala Arg Ala Lys Phe His Trp Gln Phe Leu Glu Gln Phe 35 40 45 Pro Ala Ala Gln Asp Cys Ala Tyr Lys Phe Ile Val Cys Glu Asp Lys 50 55 60 Pro Gly Ile Pro Arg Pro Ala Leu Asp Ser Trp Asp Thr Glu Tyr Met 65 70 75 80 Gln Glu Asn Arg Trp Asp Glu Glu Ser Ala Ser Phe Val Pro Val Glu 85 90 95 Pro Glu Ser Asp Pro Met Asn Val Asn Phe Asp Lys Leu Ser Pro Glu 100 105 110 Val Gln Asn Ala Val Leu Val Lys Phe Asp Thr Cys Glu Asn Ile Thr 115 120 125 Val Asp Met Val Ile Ser Ala Gln Glu Leu Leu Gln Glu Asp Met Ala 130 135 140 Thr Phe Gly Gly His Ile Val Glu Ala Leu Met Lys Met Pro Glu Val 145 150 155 160 Asn Ala Met Tyr Pro Glu Leu Lys Leu His Ala Ile Gly Trp Val Lys 165 170 175 His Lys Cys Glu Pro Gly Ala Lys Trp Pro Glu Ile Gln Ala Glu Met 180 185 190 Arg Ile Trp Lys Lys Arg Arg Glu Gly Glu Arg Lys Glu Thr Gly Lys 195 200 205 Tyr Thr Ser Val Val Asp Leu Ala Arg Ala Arg Val Asn Gln Gln Asn 210 215 220 Pro Glu Asn Ala Ala Glu Lys Thr Gly Ala Val Thr Val Ala Ile Arg 225 230 235 240 Arg Glu Tyr Lys Gln Thr Trp Lys Thr Leu Asp Asn Glu Leu Ala Cys 245 250 255 Ala Leu Trp Pro Gly Asp Val Asp Ala Gly Asn Ile Asp Gly Thr Ile 260 265 270 His Arg Trp Ala Thr Asn Glu Val Ile Asp Lys Asp Arg Glu Asp Trp 275 280 285 Lys Arg Ile Ser Ala Ser Met Arg Lys Gln Pro Glu Ala Leu Gly Tyr 290 295 300 Asp Arg Gln Thr Ile Phe Gly Leu Val Arg Glu Arg Pro Ile Asp Ile 305 310 315 320 His Lys Asp Pro Val Ala Leu Asn Lys Tyr Ile Ser Glu Tyr Leu Thr 325 330 335 Thr Lys Gly Val Phe Glu His Glu Glu Thr Asp Gln Ser Ser Thr Asp 340 345 350 Ala Leu Gln Pro Ser Ala Ala Gln Thr Ala Pro Val Glu Thr Ala Glu 355 360 365 Ser Asp Thr Gln Lys Asn Glu Ile Leu Val Glu Ala Glu Pro Ser Val 370 375 380 Glu Arg Glu Gly Pro Phe Tyr Phe Val Phe Thr Asp Lys Gly Gly Glu 385 390 395 400 Lys Tyr Gly Arg Ala Asn Lys Leu Ser Gly Leu Asp Lys Ala Leu Ala 405 410 415 Ala Gly Gly Thr Glu Ile Ser Lys Glu Glu Tyr Phe Ala Arg Lys Asn 420 425 430 Gly Thr Tyr Thr Gly Leu Pro Gln Asn Val Asp Thr Ala Glu Asp Ser 435 440 445 Glu Gln Ser Glu Pro Val Lys Val Thr Ala Asp Glu Val Asn Lys Ile 450 455 460 Met Gln Ala Ala Asn Ile Ser Gln Pro Asp Ala Asp Lys Leu Leu Ala 465 470 475 480 Ala Ser Arg Gly Glu Phe Val Glu Gly Ile Ser Asp Pro Asn Asp Pro 485 490 495 Lys Trp Val Lys Gly Ile Gln Ser Arg Asp Ala Glu Asp Gln Asn Gln 500 505 510 Pro Asn Val Lys Gln Asn Glu Pro Glu Ala Glu Gln Asn Ser Pro Asp 515 520 525 Thr Gln Gln Asn Gly Pro Glu Glu Gln Gln Pro Glu Pro Ala Val Gln 530 535 540 Gln Glu Leu Glu Lys Val Cys Thr Ala Cys Gly Gln Thr Gly Gly Gly 545 550 555 560 Asn Cys Pro Asp Cys Gly Ala Val Met Gly Asn Ala Thr Tyr Leu Glu 565 570 575 Thr Phe Asp Glu Glu Asn Gln Ala Glu Ala Gln Lys Asn Asp Pro Glu 580 585 590 Glu Met Glu Gly Thr Glu His Leu His Lys Glu Asn Thr Gly Ser Asp 595 600 605 Gln Tyr His Ala Ser Asp Asn Lys Thr Gly Glu Thr Ala Asn Pro Leu 610 615 620 Ile Lys Val Asn Gly His His Glu Ile Ser Ser Thr Ser Arg Leu Trp 625 630 635 640 His His Leu Met Ile Asp Leu Glu Thr Met Gly Lys Asn Pro Asp Ala 645 650 655 Pro Ile Asn Ser Ile Ala Gly Lys Phe Phe Asp Pro Ala Thr Gly Glu 660 665 670 Met Gly Pro Glu Phe Ser Lys Thr Ile Asp Leu Glu Thr Ala Gly Gly 675 680 685 Val Ile Asp Arg Asp Thr Ile Lys Trp Trp Leu Lys Gln Ser Arg Glu 690 695 700 Ala Gln Ser Ser Ile Leu Thr Asp Glu Ile Thr Leu Asp Asp Ala Leu 705 710 715 720 Leu Gln Phe Gly Glu Phe Tyr Arg Arg Lys Leu Arg * 725 730 <210> 813 <211> 107 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42373..42693) <400> 813 Met His Cys Cys Asn Ser Gly Asn Phe Ile Asp Glu Asn Ser Gly Glu 1 5 10 15 Phe Ser Val Gln Val Trp Gly Asn Gly Ala Thr Phe Asp Asn Val Ile 20 25 30 Leu Arg Arg Ser Tyr Glu Arg Gln Gly Ile Pro Cys Pro Trp Arg Tyr 35 40 45 Thr Asn Asp Arg Asp Val Arg Thr Met Val Ala Leu Gly Leu Val Met 50 55 60 Asp Phe Asp Ala Arg Thr Thr Ile Pro Phe Glu Gly Glu Arg His Asn 65 70 75 80 Ala Leu His Asp Ala Arg Tyr Gln Ala Lys Tyr Val Ser Ala Ile Trp 85 90 95 Gln Lys Leu Leu Pro Ser Gln Ala Asp Phe * 100 105 <210> 814 <211> 68 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42752..42955) <400> 814 Met Ser Ser Ile Phe Leu Thr Glu Asn Glu Leu Gln Thr Leu Thr Gly 1 5 10 15 Cys Lys Tyr Ala Ser His Gln Arg Asn Trp Leu Ile Lys Asn Gly Leu 20 25 30 Pro Phe Tyr Thr Asn Arg Ser Gly Lys Pro Ile Val Ser Arg Glu Leu 35 40 45 Phe Thr Cys Ile Lys Thr Leu Pro Pro Arg Glu Ala Glu Pro Asp Phe 50 55 60 Gly Ala Ile * 65 <210> 815 <211> 341 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42955..43977) <400> 815 Met Gly Arg Arg Arg Lys Asn Pro Glu His Glu Lys Leu Pro Pro Lys 1 5 10 15 Val Tyr Pro Asn Lys Tyr Ser Val Trp Lys Pro Thr Ser Arg Glu Ser 20 25 30 Val Thr Leu Thr Ala Ile Glu Asp Gly Leu Ala Ala Leu Trp Lys Lys 35 40 45 Tyr Glu Glu Thr Val Asn His Arg Asp Arg Ala Met Thr Phe Gly Arg 50 55 60 Leu Trp Glu Lys Phe Leu Ala Ser Ala Tyr Tyr Ser Glu Leu Ser Pro 65 70 75 80 Arg Thr Gln Lys Asp Tyr Leu Gln His Gln Lys Lys Leu Leu Ala Val 85 90 95 Phe Gly Lys Val Leu Ala Asp Ser Val Lys Pro Glu His Ile Arg Arg 100 105 110 Tyr Met Asp Lys Arg Gly Glu Gln Ser Lys Thr Gln Ala Asn His Glu 115 120 125 Lys Ser Ser Met Ser Arg Val Tyr Ser Trp Gly Tyr Glu Arg Gly Tyr 130 135 140 Val Lys Ala Asn Pro Cys Ala Gly Val Ser Lys Phe Lys Ala Lys Asn 145 150 155 160 Arg Glu Arg Tyr Val Thr Asp Lys Glu Tyr Gln Ala Val Leu Ser Val 165 170 175 Ala Pro Leu Pro Val Phe Ile Ala Met Glu Ile Ala Tyr Leu Cys Ala 180 185 190 Ala Arg Val Ser Asp Val Leu Ser Leu Lys Trp Glu Gln Ile Gly Asn 195 200 205 Asp Gly Ile Phe Ile Gln Gln Gly Lys Thr Gly Lys Lys Gln Ile Lys 210 215 220 Ala Trp Ser Pro Arg Leu Gln Ala Ala Ile Glu Lys Ala Lys Gln Leu 225 230 235 240 Pro Thr Ser Ala Tyr Val Ile Ser Asn Gln Tyr Gly Asn Arg Tyr Met 245 250 255 Tyr Lys Gly Phe Asn Glu Met Trp Val Glu Ala Arg Asn His Ala Gly 260 265 270 Lys Ile Ser Gly Ile Leu Thr Asp Phe Thr Phe His Asp Leu Lys Ala 275 280 285 Lys Gly Ile Ser Asp Tyr Glu Gly Ser Ser Arg Asp Lys Gln Leu Phe 290 295 300 Ser Gly His Lys Thr Glu Gly Gln Val Leu Ile Tyr Asp Arg Lys Val 305 310 315 320 Lys Val Ser Pro Thr Leu Asp Val Pro Leu Pro Glu Asn Ile Pro Arg 325 330 335 Lys Tyr Ser Lys * 340 <210> 816 <211> 43450 <212> DNA <213> Escherichia coli O157:H7 <400> 816 gtttgcctct cctgaactct cccgacatca acaaagcccc ttataatccc ttatatatca 60 ggttttcttt gtatcctgag gtcaaacgac tttaacccat atcaagttgt ttgtgggggt 120 gcattggggg tatcaggttg gttactggcg gaaattcccc caggaggatg gattcatcaa 180 aagctggagg atgtcatggc gctaaccgat gttaaagtga aaaccgcgaa gccaaaagaa 240 aggccctata agctggctga tggcggaggt atgtatctgc tgattaacgc taatggttcc 300 aaatactggc gtatgaagta ccgcttcgcc ggtaaagaaa agatgctgtc tattggcgta 360 taccccgatg taacgcttgc cgacgcacgt gagaaacgca gtgaagccag gaaaatactt 420 gcggctggtg gcgatccggg tgaggcaaaa aaagaagaaa aaatagcgct gcaaatgagt 480 ttgaaaaaca ctttcgaggc cgttgctcgc gagtggcatc agacgaaagc cgatcgctgg 540 tcactgcgct accgcgatga aataatcgac acctttgaga aagatatctt cccctacatc 600 ggcaagcgac ctattgccga aatcaagccg atggagctat tggaagcact acgtaagatg 660 gagaaacgtg gagcactgga gaaaatgcgc aaggtccgcc aacgttgtgg tgaggtgttt 720 cgctatgcaa ttgttactgg tcgagccgac tataaccctg ctcccgatct tgccagtgct 780 ttagctacac cgaaaaaagt acattttccc tttcttactg ccaatgaact tccccacttc 840 cttactgatc tggcgggtta taccggaagt atcatcacta agacagctac tcagatcatt 900 atgttaaccg gtgtacgaac gcaagagttg cgtttcgcgc attgggagga tattgatttt 960 gaggcaaaat tatgggagat cccggcagaa gtaatgaaga tgaaacggcc tcatattgtg 1020 ccgccctctg agcaggttat tgcgctattt aagcaacttg aaccaatctc aaaacatcat 1080 cctctggtct ttatcggtag gaacgatcct cgcaagccaa ttagtaagga gagcattaac 1140 caggtcattg aattgctggg gtataaggga agactcacag ggcacggttt caggcatacc 1200 atgagcacaa ttctgcacga acaaggcttt aattctgcct ggattgaaat gcagttggct 1260 catgtggata aaaactccat caggggtacc tataaccacg cccagtatct cgatggtcgc 1320 cgtgaaatga tgcaatggta cgctgactac attgattcac tttctgagct ggcctgatga 1380 atgaaagttc ggtgacacaa aaataatgaa taaccatcca gccccaacag gcggatggtt 1440 gtagtggcac agtaaatttg gccacctgat taaaggtgat atcctcacca caacacaaaa 1500 caggtgactt aatgaacaag aaaaccaaac gtactttcac ccctgaattc aggctggaat 1560 gtgcacagct aattgttgat aagggctact catatcgaca agccagtgaa gcgatgaatg 1620 tcggttctac cacgcttgag agttgggtgc gccagctcag gcgagagcgt caggggattg 1680 cgccctctgc cacacctatt actccagacc agcaacgtat ccgcgaactg gaaaagcagg 1740 ttcgccgcct ggaggaacac aatacgatat taaaaaaggc tacaaccgcg ctcttgatgt 1800 ccgactcgct gaacggttca cgatagttgc cagactgagt gacagccact cagttgtcag 1860 cctctgttct gctctggaaa tacaccgcag cagttaccag tactggcgaa aacgacgcga 1920 tacggttaat ccggcgcgag tcaggttgtg cagcgaaata cgccgggcgt ggaaccaaag 1980 taggggctct gcgggggcgc gcacgctggc tgaaatgctg acccaaaacg gcgtcccgat 2040 gagccgttac cgtgccgggc gtctgatgaa atatctgaac ctgagcagtt gtcagcccgg 2100 aaaacatcag tacaaaaatg ctcgtcagga acatacctgc ctgccgaatc tgcttgagcg 2160 ccagttcgct gtgcccgagc cagatagggt atggtgcgga gatattacgt atatctgggc 2220 aggaaatcgc tggtgctatc tggcggtcgt catggatctt tttgcccgca gggttatcgg 2280 ctggagcctg tcagcgaatg ccgatactgc cctgataagc agtgccctgc ggatggcgta 2340 tgaggtgcgt ggtcagccgc gggacgtcat gttccatagc gaccagggaa gtcaatatac 2400 aggactgaaa tatcaacaac ttctctggcg ttacaggata aagcaaagtg tcagccgacg 2460 gggaaactgc tgggataaca gtccaatgga acgcttcttc cgcagtctga aaacagaatg 2520 ggtgccaacc gatggctaca caggcaaaga cgtggcccgg cagcaaatca gcagttatat 2580 tctgaattat tacaatagcg tcaggcctca ccattataac ggagggctga cgccggaaga 2640 gtcagagaac agatatcatt tttactgtaa aaccgtggcc agtattactt gaccactaca 2700 ctggaactca tgctcaccag cggtgagctg aatccccgcc atcagcatac cgtcacgctg 2760 tatgcaaaag ggctgacctg caaagccgat accctcggca gtcgaggtta cgtttatatg 2820 gctgtttatc cgacgcccga aacgaaaaag taaatcatca gaataacctt ctgctccggc 2880 ctggtgtttt caccacgcca cttccccatt tctcatctct gcatatcagg aaaaacttta 2940 gtatgaaaac attacccgat acacacgtac gggaggcatc gcgctgcccg tctcccatca 3000 ccatctggca gacactgctt ggccgtctgc tggaccagca ctacggcctc acgctgaatg 3060 acacaccgtt cgctgatgaa cgtgtgattg agcagcatat tgaggcaggt atttcactgt 3120 gtgatgcggt gaactttctc gtggaaaaat acgtgctggt gcgtaccgac cagccgggat 3180 tcagcgcctg tacccgctct cagttaataa acagcatcga tatcctccgg gctcgcaggg 3240 cgaccggcct gatgacccgc gacaattaca gaacggtaaa taacattacc ctgggtaagc 3300 atccggaggc gaaatgatga aactggccct gacactggaa gccgacagcg ttaacgtaca 3360 ggcactgaat atggggcgaa ttgtcgttga cattgatggt gttaatctcg ctgaactgat 3420 taacatggtc tgcgataacg gctactccct tcgtgttgtt gatgaatctg accggacctc 3480 agcagactgc acgccaccat ttactgccct taccggcata cgctgcagta ccgcacatat 3540 cacggaaacg gacaacgcct ggctgtactc gctgtcacac cagaccagtg acttcggtga 3600 atcagaatgg attcatttta ccggtaacgg ctatctgttg cgtaccgatg cgtggtcgta 3660 cccggttctg cggcttaaac gcctgggtct gtcaaaaacg ttccgtcgtc tggtcgtcac 3720 actcatccgg cgttatggtg tcagtctcat tcatctggat gccagtgccg gatgtctgcc 3780 aggtttaccc acttttaatt ggtaactagg aacaacatga catcattaac cccggaagca 3840 gcactggata ttctgattgc gtggctgcag gacaatatcg acagcgaatc cggaattatc 3900 ttcgacaacg atgaggataa aacggattcg gcagcattgt tgccctgtat cgaacaggtc 3960 agggaagatg tccgtaccct gcgccaactg cagcttctgc aacagaaccg gtgagtctca 4020 ctcaccatac ttcattccac tgacgccagc ctgaacaggg ctggcgtttt cgtttataaa 4080 ccaaaaggaa aaccgataat gtcaggcatc ataatctccc gtccggaagt ggacaccggg 4140 catacggacg ttatctgctc caccagtatc cgacacgttg tgacggtacg gaatgcagca 4200 ctgcaacaaa ccgaaacgct tatccggcaa ctggcagaaa tctcagtcct gacagcagca 4260 gacattggcg gcaaaaccgc cctggaccgg gcgatgaaac aggattttca ctgcggctgc 4320 tggctgatgg agaaacctga aaccgcaatg aaagccatca cccgcaacct cgactgcgaa 4380 atctggcgtg acctgatgca acgctccggg atgctgagtc tgatggatgc acagggctag 4440 gatacatggt accgctcact ggagtacgat aatattccgg aaatcagcga ggcgaatatc 4500 atgaatgcat tcaaacaact gcaccagagt aaggatgaag tgtttgagcg tggggtgatc 4560 aacgtcttca gagggccgaa cggaattaca aaaccaattc cccctgtaaa ttcggcagta 4620 aaattatcgt caacaacttg gtgagatggg acagatggag atttcatctt atcagtggaa 4680 tgcaggcaga tcgcttagct gacctggaaa gaatgttgca tctgctcagc ggtaaaccgc 4740 tccccaacaa ccgagggaat atcaccatta atctggatga ccacctacag tccgttcagg 4800 gtaaagagcg ctatgaagac aagtaaatac tttaagaagg gcccgcacac atcacattca 4860 gaaagccaga gctggttgac aggcttaatg atattattgc cagacactac ctaggaatgt 4920 taccttcaca aaaatctcta agaattgatt caattgtgta ttttagcctc attccctcat 4980 gtaaagtcat ttgggggtta ttatgggggt caatcattta tccaacacgc attaatcatt 5040 taaaatcaat gcattaataa tcatattcga ctcctgtgat ctccgccaaa cttcctcttc 5100 tgaactctcc cgacgtcaac aaaagtaagc gtacagcctg aaccgtctgg tcagaatctg 5160 acgaattaga caaagtggtg tccaccaaat aagtagtggg aaccaaagta tcagatatgc 5220 agaaaaatgt gactcccggc aggcgaaaag gctgccctaa ttatcctccc gaatttaaac 5280 agcagctcgt tgctgcctcc tgtgaacccg ggatatccat ctcaaaactt gctcttgaaa 5340 atggcattaa cgccaatctg ttgttcaaat ggcgacaaca atggcgcgag ggaaagctgc 5400 tattaccttc ttcagagagc ccccagctac ttcctgtgac tctcgatgca gctgccgaac 5460 agccagaatc gctcgcagag gacccggaaa ccctcagtat cagctgtgag gtaacgttcc 5520 ggcacgggac gctccgcttc aatggcaatg tcagcgaaaa gctcctgact ctgctgatac 5580 aggaactgaa gcgatgatcc cgttaccttc cgggaccaaa atttggctgg ttgccggtat 5640 caccgatatg agaaatggct tcaacggcct ggctgcgaaa gtacaaacgg cgctgaaaga 5700 cgatcccatg tccggccatg ttttcatttt ccggggccgc agcggcagtc aggttaaact 5760 gctgtggtcc accggtgacg gactgtgcct cctgaccaaa cggctggagc gtgggcgctt 5820 cgcctggccg tcagcccgtg atggcaaagt gttccttacg caggcgcagc tggcgatgct 5880 gctggaaggt atcgactggc gacagcctaa gcggctgctg acctccctga ccatgctgta 5940 aatctcttta tcctggttgt cacagaataa gcccggtaaa atacgggctt atgaacgaca 6000 tctcttctga cgacatcttc ctgctgaaac agcgcctggc cgaacaggaa gcgctgatcc 6060 acgccctgca ggaaaagctg agcaaccggg agcgcgaaat agaccatctg caggcgcagc 6120 tggataaact ccgccggatg aacttcggca gtcgttccga aaaagtctcc cgccgtatcg 6180 cacaaatgga agccgatctg aaccggcttc agaaagagag cgatacgctg actggtaggg 6240 tgtatgaccc ggcagtacag cgtccgttgc gtcagacccg cacccgtaag ccgttccctg 6300 aatcactacc ccgtgacgaa aagcgactgt tgcctgcggc gccgtgctgc ccgaactgcg 6360 gcggttcact gagctatctg ggcgaggata ccgccgaaca gctggagttg atgcgtagcg 6420 ccttccgggt tatccggacg gtacgggaaa aacatgcctg tactcagtgc gatgccatcg 6480 tgcaggcacc tgcaccttcg cggcccatcg agcggggtat cgccggaccg gggctgctgg 6540 cccgcgtgct gacctcgaag tatgcagagc acaccccgct gtatcgccag tcagaaatat 6600 acggccggca aggtgtggag ctgaggcgtt cactgctgtc gggctgggtg gatgcatgct 6660 gccggctgct gtctccgctg gaagaggcgc ttcatggcta tgtcatgact gacggcaaac 6720 tccatgccga tgataccccg gtccaggtac tgctgccggg taataagaag acgaagaccg 6780 ggcggttgtg ggcgtatgtt cgtgatgacc gcaatgcagg gtcagcgttg gcacctgcag 6840 tgtggttcgc ttacagcccg gacagaaaag gcatccatcc gcagactcat cttgcctgct 6900 tcagcggtgt gctgcaagcg gatgcgtacg ccgggttcaa cgagctgtat cgcaatggtg 6960 ggataacgga agctgcctgc tgggctcatg cccgccgaaa gatccacgat gtgcacgtcc 7020 gcatcccgtc agcactgacg gaagaagccc tggagcagat cggtcagttg tacgccatag 7080 aggcggatat aaggggaatg ccggcagagc agcggcttgc tgaacgtcag cgaaaaacga 7140 aaccgttgtt gaaatccctg gaaagctggt tgcgtgaaaa gatgaagacc ctgtcgcgac 7200 actcagagtt ggcgaaggcg ttcgcgtacg cacttaacca gtggccggca ctgacgtact 7260 atgcgaacga tggctgggtg gaaatcgaca acaacatcgc tgaaaatgcc ctgcgggcgg 7320 tcagtctggg tcgtaaaaac ttcctgttct tcggctctga tcatggtggt gagcggggag 7380 cgccactgta cagcctgatc gggacgtgca aactgaatga cgtggatcca gaaagctacc 7440 ttcgccatgt gcttggcgtc atagcagact ggccggtcaa ccgggtcagc gaactgcttc 7500 cgtggcgcat agcactgcca gctgaataac acatccccgt caatacggcc ctcgctgtac 7560 gcttaccaac aaaacccctt ttaatccctt atatatcagg ctttctttgt gtacaggggt 7620 caaccgactc aacctgtatc aagttgcttt tgaggatact ttagggggta ttatttcctc 7680 ttgaaatatt agcaccccat aatgggaaaa aggtaataca taacaatggt ttttaacagt 7740 atctttgtta tacaaggggg cattgaggat atcaggaaaa atctcaaaat cggtacggac 7800 aggaaactac gtgggcagca aaaacgtatg gtaacaccgg gaaatgcaac gcccaccagt 7860 cgggctaatc caccactcca atcgtggttc gcagtactgc acacacgatt accgggctat 7920 acaggagcgg tttggtctga aaacatccat gccgcgtaaa ggtaaccgtt acgacaacac 7980 ctcaatgaaa aacttatagt aaacgctgaa gaatgaaact atcgttttaa taaccgggat 8040 gaagccatct aagtaatacg gaaatacatt gagattttct acaaccatca gcgccgccac 8100 tcccgtctgg ggaatatctc cctggtagcc ttcaagaaaa atataaccag ataactgcgt 8160 aaaaaaagaa caaatggtgg tgtccgctat tgccagtata cctgagttta ctgcctttca 8220 gattatcaca atcaatagcg aacagacttt taagctctgt gcgcttttaa caaaacgtcc 8280 ctttctccac tttcaccgta taataataca ttatttatta cccctccaat aaaaaccgat 8340 attactaatc acatttatta ccacacaatt tgatatcggt ttttattagt tggttaccct 8400 ttcttcgatt gctcataggc agctaaatga tcttttaatg cctgtgcaag gggcggtagt 8460 ccactaggcc ctgtcggtgg cggtggtgcc tgacgggcgg gcttaaaacc taaagcctca 8520 ggacctttcg atttttcata ggcagccaag tgctctttta atgcctgtgc aatgggcggt 8580 aaaggtcggg atgccccgga tgcctgtcca cttgtcggtg gcggcggtgc ctgacgggcg 8640 ggcttaaaac ctaaagcctc aggacctttc gatttttcat aggcagccaa gtgctctttt 8700 aatgcctgtg caatgggcgg taaaggtcgg gatgccccgg atgcctgtcc acttgtcggt 8760 ggcggcggtg cctgacgggc gggcttaaaa cctaaagcct caggaccttt cgatttttca 8820 taggcagcca agtgctcttt taatgcctgt gcaatgggcg gtaaaggtcg ggatgccccg 8880 gatgcctgtc cacttgtcgg tggcggcggt gccggacgag agggagtaaa tgaagtcacc 8940 tggctgctca cattaaaaat cgttctcgca ttaacattcg acgagcctgg agaaaaaggg 9000 gaatgaactt tcaccggagt aagacgcacg gcctgagggg ctacagaaaa tccagttccc 9060 cccgcagagc tcactcgact tgcgatacct acaagctgcc gccctagtgt agaagcagcg 9120 ttactaattc cattaagcat aatttatgcc tctttatatc taagcttggc taactctcat 9180 atatatcaaa acgaataata aaatgatttt taaatcaata taaattaaaa tcctcgtacc 9240 cagccactac cattctcatg gaccaaactg tacaataact gactcgtctc atcatccata 9300 cagtcctcca aagcctttac cgcatcattt tttctattta atccaaataa gataataaat 9360 tctaaatgtg cgatatcttt tttatcaggt ataatttgtg ggaatacatt caggatagct 9420 tccgcatatt tgggaagctt atggtttgcc gcagctacag ccgcccacac cagtatctta 9480 ttagcagaaa tatcattaac cattaaaatt aaaaactacg gttagaaatg gttgagacca 9540 gatcttttat cgttttcaac attccacttt ctacgttaac ataagcagaa tattgctgaa 9600 ccgcaaactg caactctaac attttttcag ggtcattaac caaatcggtg ctattaagta 9660 actctggcac agaatcgctc agcgttttac ctacttcacc catttgttga gtaatttcag 9720 ataaattcat taaatttccc tcagaagtta ataaaataaa aacttttaac tatttacgtt 9780 cattacgaac caaattccgt cttctgtttc ttgctgcacg gcaccctttc tgatgaagta 9840 attaaacaac tcttcgcgct tttgacgttc tgaatctgaa ccaatcttag atttcatcgc 9900 gctgattttc ttaatacccg aaaaatggtg atacaactct tcgagcaaat gagtcagcga 9960 taaaacaggg ccgttaagcc ctgtttggtt acgtgcttca aaagagcaca aaatcagttc 1002 0 ttgttcatcc agtctgtacg ctaatgaaaa aaaaggtgtc tcaatccgcc atccgataaa 1008 0 aaaggcactg ccacaaagaa actccttctg tattgtgtac cctttttgtt caagatagta 1014 0 attaaacact tcatcattaa acgtatcgac catgatcaat tacccagcta agcgacccga 1020 0 ttgccccata cgattctgga cctcaaggag atcgcggaca gcggacgtta tatcacgcag 1026 0 acgagtcgtg atatcatcct gcgttctgcg aacgtcttgt ttatacagct ccagattccc 1032 0 ctgctggaag ttttccagcg acttcgcacg ttgttcatta acctcatgag tcgatttgac 1038 0 ggactcagat attgttgttg gcaacgtttt cgtaccttca gcaagactgg tcacggcaac 1044 0 aaatgctgtg gtattggtca gtttatctac ggaattcaac aacttattga ttctgcttgt 1050 0 cttctcggcg gcgtctgcaa gatcttcagc aaagtcagag gctttcgcaa catcatctgc 1056 0 aacgccagat gcacggctgg ctgctttcgt tgttgtggcc atcgctttct gcatcgcact 1062 0 ggatgcctcc tctgcgacat cagcaacact ttccgtagcc ttgaccagag ctttatttgc 1068 0 aacctcagaa gccgcaccag cagcctttga agatgcagag cttgcttttt cagcaatctc 1074 0 accagcccct ttagccgcgt tgttcattgc tgcaaaagaa cctaagatcc ccaatgctga 1080 0 tgaaataatc ccgccaacca aagcagcggt tgccgcggct tttttttcct caatagcttt 1086 0 attctggctc tcaaaaacgg cctgctgaat ctgatagctt tgcgccaatt gtttttgttg 1092 0 gtaatcctgc aatagagtca ccatcttgcc gaggagtttt tgaatttcca gcatcagctt 1098 0 acaaatatca accttaccat cagtaagcag agatgaatca attgataaag cagatgcggc 1104 0 aactgcactg gaagcgccgg tcgtactctc cgaagcggaa ttaaccatcg ttacttgagt 1110 0 attatcaata gtattcataa taaaattctc tttaataatt aaattcggcc actaacaata 1116 0 cgactattta cccgtgctga atcggacatc agttgagaaa cactttgtaa atagctcgcc 1122 0 tgattttgta actcgcttgc cgctttatcc agctcgagct tcgcactctc acctaagctt 1128 0 tcactctgtc gagttaagtt ttgcaccgcg aaagcagcta actgagacaa catttggagt 1134 0 tgcgcagcct cattattcaa cgcagttgtc ccggcagaac gaataccgtt cgtaacgccc 1140 0 tcagccactg tcgaaatttt tgcaaaaacg tttttaacca gcgcttctgc cgccttctca 1146 0 acgactttta caacgcttga gccaattttg ttagcaacat taccaaattt agataacagt 1152 0 gaagacaccc cgccaacgcc ggctgtcaga atgcttgcgg ccatagatat tccgccaaag 1158 0 acctgtgctg cagtctttaa tccctgaggg gcattttccc ccattacatc gactgccgtt 1164 0 tgcagtgcca ttgctgttgc accaatggca acaacagccc agagtgctgg gttaaaaaca 1170 0 gcggcaacgg ctgttaatgc gacgcccaac caaccaaaga cctggccaac aattttactt 1176 0 ttttgtgatt tctcttcggc tttctgttgt tcttcgagct gttttttata ctcctgcgtt 1182 0 ttattctcca gcgctttagt ttgcccatcc atataaatct cgttagagtt tttcagactc 1188 0 gagactttct gcgcggaagt atccagggat aacagagtga ccatcatcat catttgctga 1194 0 gggtcaacgg tattcacctg agagagatag ggatagcttg tgcgctgtgg ctctgcctcc 1200 0 tcagtgcgac ttgtaacctc accactaata ccaccaaaca atttactaag gacatcctca 1206 0 gcagcagagg gcgtcactaa tgagtgacct gccggcggcg tcggtaaagg gctactttct 1212 0 gtccagcctg ctgacgagtt catggattta accagttgta aatccagcga taaacccgtt 1218 0 tcagattgag taataccaga agtacccgag gcggtattaa ccccagacgt tacagacagg 1224 0 gtatcgttat ttacgttaag catagttatc tccggttatt taccaaggga tattgctgaa 1230 0 atagttctat attgtagaga ttgcacatca gaacgtgcac tcgttaagag atttaatgta 1236 0 ttcgacattt gctgaatttc gagctggcta ttattcacta ccgttgtcag gttattcgct 1242 0 ttagctgaaa tagccgcctt cactgtttgc agatcaccag cgcttaaatc accactaaga 1248 0 tcacgaatac cagttacact tatgtcatta cgtggatcgt ttatatagtc aatcacgtct 1254 0 tgaggaagtt tggctttcgc attcttatca gtgctactct gaacatcagc aattttggca 1260 0 tccacaagat tagccatctt ttgtgccgtg gttgacgctt tagatgcctc attcatatca 1266 0 gcaaactttg caatcgacag attactttgt gcctgataca tataagaaaa catgagaatc 1272 0 gcagcctgaa aaacaccgag ttcctcaaat agcttaacca cctcatcctt cgacatatta 1278 0 cctaagtcat agatcgtcga tgtcgaagaa ctcgcactca cattaacaac ggatgttgca 1284 0 tttgatgtat ccatctatat acctcttgat aatttttctc aggaaaacaa aaaaattatt 1290 0 gagtaattaa tatcaaataa tttcctcctt atagtcgata actttaccaa tcattaataa 1296 0 tgcattctct ctctgctcac tatcaataaa gcaagcatct ggtaatgatg taaaaaagtc 1302 0 tttcaataaa tgaaaataat aaatatgttt atcttcgaca atcgataccc gagaaggact 1308 0 ctccagcaac cagtcttctg ttagccagac atgttcaata atcgataaca cttcatttaa 1314 0 aatgatatct ttatctttct taatagagat cgaaataata tctgcatagt tatcaagtga 1320 0 taaaaaaatg attaccctgc ataaatcact aataattgaa gatgtcttta ctttgtcttc 1326 0 aaaagaagac atataagaga gatcgaacga cagcgcccta ataatgactt ttaagtgctt 1332 0 ctcacgctcg ggaagatcct taatctccat aaaccagtca agtaaagagg cgccattttc 1338 0 agaatcctca tccttagcct tttcataaag cttcttgatc ttctggatac cttcctgatt 1344 0 taactcaccc acccctaacc aggaaagcag agccagctcc caatcatctt cgcctaataa 1350 0 atctaataat aacctggcat atttcttttt taattcaatc ttaacaaact tagattgcaa 1356 0 taaagaagat attagcgcaa caatttcccc ctttggcatg ttgccaaaca tcgccaaagt 1362 0 aggatcgtgt tgttccagca gcccgctgtt ttttaatgat agttctttta ttttatcact 1368 0 atcggtaaga gtaagcagct cttgcatatc attgagcagc ttctcgattg tcgagccttc 1374 0 ctcttctttc cttgcgctac ctttgcgata tcccaggctt agcccttcaa tcgtttcaga 1380 0 aagcgatgaa ctagtaatca ttgctaattc attttgcaaa tttattaatg gcgaagaaat 1386 0 attagaagaa tttttttgcg ttaattgctg agattctaat tcaaaatcta atgaattaga 1392 0 attaaaaaca gatgcggggt tttgattaaa ttcaatacca ttagccattg gaaactcacg 1398 0 taatcattaa ttatgaatat tccattaaat agtactgtac aacagcttcc tttctactct 1404 0 attcttagac gatgtaagtt caccatattt tttctcattg ttcaaccacc aggatgaata 1410 0 aaatttaaaa atgttatcct catataaaat aaaacttctc aatggtgcga tgcgtaatcg 1416 0 ggaattacaa cttccgatgg gaaacctaac gctaggtacg gaagataacg atattgttta 1422 0 ctttcccctt gaacaaggcc tcaatcagtt tttacttgat atacgtgagg aaggtgtttt 1428 0 ccttttatct ccggttgaat tttggattga tgggcaaccc acgccctatg aagcagataa 1434 0 accattacct gtcggaaagg ttattgatat agcgggatgt tgcttcatca ttggtgatat 1440 0 tgaccattcc ttgccattgt ctgatgtgcc agaaaggttc tctgccaaaa gtcgacgcaa 1446 0 aaaacgcctt atcctggcga gcgtgattgg tgctactttt gcgttgtctg gtgccatcgg 1452 0 cagttacgtt ttgctttccc caaaagctga acccccaacg tttaccagag ctgatgtata 1458 0 tcagcagcta aaagaaaaca aacttcatgc aatcactctg gtatggcatg ggaaaaatat 1464 0 cgcgctttat gggcgttgcg aatcaaccac ggatttaact ccatttttta attacctaaa 1470 0 agaaaaaaat attttttatt acaataatat catttgcaat aaccaaatca tatccgcaat 1476 0 taatgatgtc ttaacggaat acggttacaa agatatcatt attacaaaag gtaataagcc 1482 0 tggattcttt ctgttatcgg gatacattcc cccttcaccc aaatggagcg aggttgaaaa 1488 0 tctgttactg aatacgccag gagttgcagg atgggaaata cacaacaaca gtaacaataa 1494 0 aatcaatgaa ctggcatcag agtttaaaaa gaataaacta ataaactatg tcaatatttt 1500 0 caaaaagaat gatgtcatca ttgttgcggg ggaagtttct caacagaatg agagtaagat 1506 0 ccttgccatt ataaatgcaa tgaacaaaaa tagtaacgcc aagatactct ttcagaacat 1512 0 tcagccgtac atttcagcag atattttccc cggaaaaata ctcagaatca gcggtacgat 1518 0 gaagaatcca acaattgctc ttgataatgg caccagcctg gggattggta gcattctgaa 1524 0 aggaggctat gtcatagacg cgattgatcc taaagatggt atcaacatct cccgcccaga 1530 0 cgaatatata catattccac tgtcgtatta atttcttatc ctcttccccc tcttcggagg 1536 0 gttttttatt gtgtggatgt tgtgagcata gttgttgctt gatgtgattc agctttggta 1542 0 tcagcgtggt tggatcaacc tacatgagaa aacgtgaatg tgtctctttg aaagagacct 1548 0 attaagcaga taaaaagacc agtagtagat ttgattataa gaggttattt cttaagaaga 1554 0 aataattatg ccccgactaa aacaatacat attttagccg gggtggttat ggaattattc 1560 0 tacacaaacc gcatagacat ttggagtatt aacattaacc ccaggaagag ggttttgtgt 1566 0 tattaggtta taagtgcttg atactccaga acgctgctca ctagatgtct gtttaatcca 1572 0 agcagttatt gagttcatag aactataatg gctatattta tttgcagccc cccatgagtc 1578 0 ataaatatct gacaataccg tctgtgtgga tggtaataaa tttttgcaaa tggacatagc 1584 0 atcagcataa taggcttgct tatccacttt tatcatatac gacggtgctt ttatagtgta 1590 0 acttactgtt tgcttatcac cagatgtggc tttaattacg acactgcctt taccattcaa 1596 0 agtgactttc cctgatgcat cgacagtcgc gatactggta ttttctgaat accatgaata 1602 0 tgtaccatca ccaccgcttg ctttcagttt aaactgacca tattgcagcc aaatattagg 1608 0 caactcgcct ctgacattgt taccaataat atcaaccttg ttgtcaattt tcagttcatc 1614 0 aaaaaaagtg acctcagtcg ctttaacctc agccccatca ctgactgtcg cactaacagt 1620 0 cgctttaccg gcggaactgg aagttagtgt tatcgtcgca cgaccatcat ttcccgtggt 1626 0 tgcttgcgtt tgagacttac cgttgaacat cccaaagttt gttgagaatg taacggattg 1632 0 attattaact ggctgaccgt ttttcataac ttttacagta tatttaatag catccttacc 1638 0 atttgctact gcagttgtct tatcagcctt aatctcagta atgctggcct tggtttgatc 1644 0 aaaaaatata accgcactgg cattaagtgc tgaagtcatc tccgcggttt tagcagacac 1650 0 gacgacctgt cctggcgtac tcgacttcaa cgttacggtt gccttaccgt tagcatccgt 1656 0 tttggcacta tttgccccaa gagttgcagt tcctgaaaca atattaaatg aaacagggac 1662 0 attagcctga gctaccccat tctttttcac cgtcgcggta taagtaatgg tatcggcgtt 1668 0 atccgcttta gccgaagtct tatccgccgt aaagtccgtt accccaacct ggtcgacaac 1674 0 ttgaccattc gacagaacgg taatagtaag ctgtacattg ttagagctat tgccattacg 1680 0 gtcataggcg cgagccgtca ctttataaat attgctgcca ccttgcacat aagcaggcaa 1686 0 aatagcctgg tagtcttgtg cgctttggct tccgctatgc tgaatctgac cgccctgact 1692 0 gcgtaatgca ctatcatccc agacgatacg atccagaccg tatttgctct taacgatcaa 1698 0 ctgaatcttc tgcgtactgt gttcagtacc attaatatca tgcggaatat tcagagaaag 1704 0 aatatcctgc ttcttgtact ccagaataat attgttatta cgctgaacca gatcgtaacg 1710 0 gctgcctgat aatgttctta actcgttaac atactgtggt tcaatttgct gagaccacga 1716 0 tttatcaaac tgataacgga actgcattga gtaaaggaga tcattttcat tacccgtacc 1722 0 atgacggtaa tcgatcccca tcgtcaccag aggaatcgga gtatagttta caccaacggt 1728 0 cgccgcacca ggattcgact gcagcttatc agaattaaac aaagcaacat tatcaccata 1734 0 atactgctca tatatcagct tggcgcctaa tgccggatat gacggtagat agccattaaa 1740 0 acggatatcg aagccatttg ctgggcgctc atcatagtct ttcttattgt atgactcatg 1746 0 ccagccgctc atgcggaaat agccgttaac gctacttttg aaatagtctc gccagtattc 1752 0 gccaccaata cctaaacggg tattatcacc agaaaaatcc tgatcaatga agacgttata 1758 0 gcccaacatg tttgcaggaa ggaaaaaacg ctgacccgca cctaaatttg ccgtaaagcg 1764 0 ggagtcaatg taacgcgctc cgacctgacc aaatgccagc attttttcgg aatcatagaa 1770 0 cggtaataag aagtccagtg aactaccgtc aaagttatta ccactctgca gattaacctc 1776 0 tgccgttcca taatgttgta accaggcctg caactgtgac gaagcctggt taccagcgat 1782 0 accaagagcg gtatctttcg cgtaatcgcc gttcagagat cgcgactgaa gctggctacc 1788 0 gagactcgcc gcctgttgtg ccgcataatt taatgccttg tcatcggtca tgttgctttt 1794 0 ggtcacgtcc ggggacattt tagtcagttt attcgtgtga ccagcaacac cacctgcagc 1800 0 aacaagaggt gccgaaccta aaagtggtag tgcactgtat tcaaagggaa gttttttgag 1806 0 tggcaaaatg atctgctgac caggcgcggc cttcatcatt tcgctttcag aactgtataa 1812 0 atgcttattc aacgaccaaa tcgtcgataa attaatatct tgcgatttag aaagatcggc 1818 0 aacagtttca ccagttttca acgtataaaa aaggcgattc tgatagctat catgagttaa 1824 0 cagttttgaa tccgaaccca atttaaaata attttcacca tttgcaaatg aattctgatt 1830 0 aacataaaaa aacaatccta aaccagcact aagcataatc aatgtttttt ttagcttatg 1836 0 cttgtgccgg gtccgggtat aacaaccatg agtaatcatg ttatggctcc accacaatga 1842 0 gttagaatga gaaataaatt atattaatag atcggatttt atcttccggc gtaataatgt 1848 0 ttattgtcgc ttgaactgat ttcctctatt ttcatatgtt cgttttctaa tgttattccc 1854 0 tgattatgta ataccaaata caggttttcc attgacttaa caacgacttc tatttcattc 1860 0 tcgagttttt caggggtagc atcatcgaga gggaaacgta acgctaacaa cagcgattgt 1866 0 gctccagcct catagcacag atatggccca ccattctctg caaaccataa gtttgcattc 1872 0 aaaatctcaa gagcgaagtt agagttatct gtcgggaatt tcccacagac accataaatc 1878 0 atcatatatt cgtcattggc atcagataac gaaatataat aaatttcatc aatagcaaaa 1884 0 gaacacaatc tgttttcatt aaatgaaata gatccaatac caattttttc tgcaaatttt 1890 0 tctaataaaa gttcagatct tgatgacatt gtattttctc ttaattaaat ttatatttac 1896 0 agaagctcaa gagttgccca tcctgcagca atgttattcc ctgaaaaatt gacgttagtt 1902 0 agacttcccc cctccctccc tctaaataaa atgattatgg atatatttag acgaaacgat 1908 0 gggatcccgg cgctggtggg ttattcgaag tattcacagc gctattactc ccccccgtta 1914 0 atcctcccat gtcatggcgt aatccaccac ttagcgccag acgcgcataa gtgctttgaa 1920 0 tccccgcact tggatttcct aataaccgtg cgccgttatc agtagtatcc cggggaggat 1926 0 gttgaatggt gctatataca acagaatctg tattccccat attctgaaca gacgtattag 1932 0 aattagaagt cggcacctgc gaatcatgca gcgatgtttt aacatcagca tacggattct 1938 0 gcacggtccc tatgctggaa gtgtcaaaga aagtcgacga ggtgctagcc atcgagctac 1944 0 gtctgctctc catggtatct tctgacccag gggtatctac attgccctgt gcaggtgtat 1950 0 tatttgcagg cttattctct accgtacgtg cgcttgtagt tgtagttgta gtagttgttg 1956 0 ttgttgtttg ttctaccggc tgattttttc gatgaagcgc agcggtgacg gcaacaccaa 1962 0 ttcccccacc aagaatcaat gcgccactaa gaccgtagcc agcccccgat gaaactttca 1968 0 gctcctcctg gcgtttagct tgttgttcat catatttttt ttgcgcctga gcattatttt 1974 0 caatggcttg ctgtttggcc tcttcgcctg ctgctttagc ctgctcttct atattcgcaa 1980 0 caacatcatc tttcaatacc cctgacggaa tcgcatttcc gagctcatcg atattaactt 1986 0 tttgattatc tgggttctgg aacgcttctt tcgttaactg atctcttgtc gcagtttcag 1992 0 ttgcacttgc agctgcatca gggtcggtcg tggttgggct atccggctcc ggcgtcaatg 1998 0 caagcgcctg tacaataccc gtcgccgcca accctatcag acctgtagca acagtcccca 2004 0 acgccaacca aagtttagga tctgaacgaa ggctggaagt tgaggttgag gtctgagttt 2010 0 ctgtggtgtt ttccgcaccg ctatttgact ccctcaactc cccaacgcct tttgactccc 2016 0 cagcaccttt ggactccccg gtccctttgg gctctaacag ctccagtatc ctttggcggg 2022 0 cttccgtgat atctgaagca acggtgacca tagcatgccc agcaccacca cggcctccag 2028 0 taaatacaaa tttgtcttta ccttcaggat caatggactg caagcgagcg tactcttgat 2034 0 cacttaaaac aacagaggtc tcaacaccat tcctctgacc gacagcaata tgtttaccat 2040 0 cttcctgagt ttcaactcga aataccgaag agccaatctg cctgttaaga gtatcgagcg 2046 0 gaccatgatc atgaagaact tcaaatccat cattcagtgt tatctcagac gccgccaggc 2052 0 gcatcggatt tacaggaagt ccaggaacat cactggcacg attgtcgcca gaatcagcca 2058 0 tagaattcct tacaggcgta aatagcgcac gagatcccaa cggccccgta gagttaatga 2064 0 gctgaccacg cccccctgca ccgtcggttt gtgaaggtaa tggaggtgca ggaggaattg 2070 0 aattattcac attgggatta tgaccaagat taccaatagg cataaatatc tcctttttat 2076 0 tttatgtaaa tagataacaa tcctttattt tgctattaca taataatgta tggtatacag 2082 0 cacgtagtcg ataaacggct gaacatgaca tcgaccaaat aaatcacaat ctgatttttg 2088 0 atgcaagaaa ataatgtgct aaaaacacac atcgggtaac aaaataaaaa taattatatt 2094 0 atataaaagt aaacaccacg tgaaatctta ataaaacatt tcataaataa aattgcagca 2100 0 aacattcatt tatattaaaa aacacagcca aagaaaacca attaagcaaa ctataaatct 2106 0 taattaataa taaagtttat taagtttctt tatcgcgttt tttcttacat caacaaaggc 2112 0 catgctatac accaggaagc ttaatttata cctgacaagg ttatccctac aatcgggtat 2118 0 cctgtacatg ctctaaaatc gcattctgag taatcgcttt tatctcactg actttgaagc 2124 0 cgctaaagtt gcgttcaaat atttcttgtg agacttgttc tatcatcttc gtctgggtgt 2130 0 taaaacgtgt tattggatcc actcttttgc cgcactgctc atcaactttc tgattaaagt 2136 0 atttattgga ctgcaagaag tgaccaattg atgattgtgc cccgttcata tcaagaggtt 2142 0 gctgtaacgc attttcaaca gctctaaaaa tgtgaccttt agtctcctta ctaatgaccg 2148 0 aattattact cctgcaatag tcatccagag ttctatttac tgttctggat atataagtcg 2154 0 tctgctcctg ctggaaccat tgttgggtat cgccattacg agtttgtttg gctacagcct 2160 0 gcaggagttg gttagtcagt ttgccatgat taatcacaaa gttcgactgc acgggcatga 2166 0 acctcatacc cgtggctccc gtacccgctt gcattgcagc tctggtaacc gcaggtttaa 2172 0 gcgtctgtgc agtcgcctga actaacgatc tgcctgccat tgtcattgga ctaaacatac 2178 0 cataaacctt tataaattat atttcgacag taaaaaaatt gcttcccatt aaaaaataac 2184 0 tttaaagaat aattatcttg tatttatatt tgaattatcc tccggcctta tctacaggta 2190 0 gttgcactac atttatcata tgctatcatg aatatgcaac actattcccg taatcttata 2196 0 tctacgcctt attatttgta tcagaactct cggattaatt acgtttgagt atatcaacat 2202 0 gaaaagaatg gcaggactac aatatgaatg agaaatttcg cacagacctt gcacatacgt 2208 0 ttgggatagc tcttgaagag caaactgacg tgctctcttt ccacgataac gatggccatg 2214 0 aatggatact ggagtgtgca tctcaatctg aaattctgtt tttttattgt tatttattga 2220 0 atagcgaatc aatacagatt aattcaatac ttgaaatgaa tagcaatcga gaactgctcg 2226 0 gtatgttttt cctgtcatta aaagatgaca acattctttt aaatattgca tttcctgcag 2232 0 ataaaattga tattacagag tttgctaatt taatggaaaa tggttatcta ttaaagaatg 2238 0 agataattag atccttgtct tccagaccta cagatttttt accttgataa tttctgcgct 2244 0 ggatgggatc atccattccg tttaacatac tcttcatcac agggacctct gatttctggc 2250 0 cgctaacgtc tctgaagatt cagcctgtat tatctaaaag caatgtaata tcagttaaaa 2256 0 agcggaaaaa ctccagaatt ataactattc tggagttaag tcaggaagaa aactcaaatg 2262 0 ctaatcataa tacgctataa gaggaagctc ttgttgctat agccctatta tcaagacgtt 2268 0 cggtagactg tacacgacgt aacaaagaag ataatcctct ttcagctaag atcccctcca 2274 0 ggggagtacg aggaaaccag gttgaagaaa gtggagttat atgtctctca tttaattttc 2280 0 tttccaaagc cttagtcaca ccgccagaaa acacgctaaa tagcgttgag aaacatccat 2286 0 tttccggtgt tattctttgt actttgtaca cataatcatc ttttgggcca tctttaataa 2292 0 agtgaacagc atagtctttg cctctaaaag agacaatggt ggaatcccct atttctggat 2298 0 atacccgatg atggcgttgt tgcattcggg ctttaagctg aatttcatct acgatatctt 2304 0 cattgggtat atgaagcctt ctgttgaacc tgttccatga cgcatgttca cttgtcagaa 2310 0 atgtcttgaa taccgctcct gataacgaca tgatacatct ccctatataa cgtattcctg 2316 0 attaatcaca tactatgcta acagtaaaat aaaaatcttc gttgattttt acaatactcc 2322 0 cgtatgctat cgtcgtatta ttgcgtatta actgacaacc accaaaaaga tggtatccat 2328 0 ctgaattaat aatgtcatct tttttaacat tacgcaacat gtgtatatca atatggactg 2334 0 taccgatcgc acaataaatg cgattcatga cagtctcatt gctaagagca gataacagat 2340 0 ccgcagccag aacatccgtg acagataaat tattatcact cagatttact gttgctaaag 2346 0 gggtattaat aacaatccag caccttctct cttgactatc atcaacatga tagagtctca 2352 0 gactatcacc aactctcaac tctgtaactg gataatcagt ccacccaggt acgatatagc 2358 0 catcaaaaaa aagagcatta gaatgtggaa ctaattgcca attatcatta atcagatatt 2364 0 gtaaactttg taccgttgtt tcgagtataa ttacattaag tctgttttct ccattattat 2370 0 tttctattac cggataaata tctttattta gcatcgtaaa ttgaacatca tcaactgaca 2376 0 catcaccttc cggtaaggca gtctgcatta cccataagat catgagtttt atcgtatctt 2382 0 ccggtatcag ccggctttcg ctatacggga ataactcttg gcaccactga atgaactgtt 2388 0 cttctgatat ccagaaacgc ccctcatagc ccgagtatgt caacgtgaaa cgaataccat 2394 0 gaccgctgac ctcacgaaaa tatgcatggc aagcatgacc tttggacgta atatagaggc 2400 0 gaccggttcc gataactggc aacaacggca aataaaaatc gttaattttc atattcaatt 2406 0 gtgaactcaa tggcttcatc aggaaagatt tcttttaact tatcgaaaac atagtctttt 2412 0 ttatgatata aaaaaacatg atttctatta tttgggctta ctttaataga cagataaatg 2418 0 attccgttac tacatttaat tgttaaaaca attcctcgta atcttccaca aagaatacta 2424 0 aacgagtgct ccccttcttc aaagtagcgt cgtcttcggc ccgaggagta aaacaatctc 2430 0 ttccataaag aagccattcg tatgaacaac gtatcaggcg atcttttttt tatatgataa 2436 0 aaaatatcat taaaactttc ttctccttgc ggccaatcat ctgatggccg aaaagaaaca 2442 0 ggctctatca aatttctttt tagagaaact ctagtcaaag taatgttcct ttatggcaaa 2448 0 agataatttt tctactgatt tattaacatg ttgcagattc tcttttgttc gtttttgtga 2454 0 atctagcaat gaacgctttt ccttcgaaag tgaagatttt ttctcataca atcgctgctt 2460 0 ttgctcatca aatgcattgt ttttaatctg atatttatac aacgacactt tatccaaatt 2466 0 caccagcgat gcacaatatg cctgcttaga ggcaatcgac tctttaatgg attgctcgca 2472 0 gtcatcgagt ttaccatcca cctcttttat ctgagagtta atcttagcca ttgattctct 2478 0 caatcggttc gctctgcttt tacgaataga taaaattctg tccaacatac tcaggcaacc 2484 0 actttgaata ggctttcaat cgttttttcg taactactga tatctttggt gctttgttgt 2490 0 ataaagttct gaattaattt cctatttttt attgccttat ctgcttcagg atcttgcccc 2496 0 atcgtgtact caccaatacg aataagcagc tcaacatttt tataagttgc aataagcttt 2502 0 ttgcattctg ccgccgcacg caaatgctcc gatgtaacaa cgttatgcat aacacgactg 2508 0 gcacttaaac caatatcaat tgcagggaaa tggttttcct ctgcaagttc tcgggtaagt 2514 0 acgatgtgcc catcaagaat agagcggact tcatcgccaa taggatcatt aacattatcg 2520 0 ctttctaaca acaccgtata aatcgcggtt attgaacctt ttggcgcagg ccccgctcgc 2526 0 tctaataatt tgggtaacga agaaaaaaca ctcggaggga atccccccct tacatcaggt 2532 0 tctcccgatg caagcccaac atcacgtgcg gctcgggcat aacgagttac agaatccatc 2538 0 attaataata catttttacc ttgatcgcgg aagtactctg caatagtcgt cgccgtaaat 2544 0 gcggctttca tcctttccag cgcggggcgg tctgacgttg tgacgaccag tacacattta 2550 0 gaaagcgtgg attgaggtaa gagcgcgagg aattcattta cttcgcgacc acgttcgccg 2556 0 ataagagcaa ggacaataat atctgcggat gcgccattac aaatcatccc caaaagcgta 2562 0 cttttaccaa cgcctgaacc agcaaaaata ccgatacgct gcccaatacc gcaagttagt 2568 0 agcccatcaa ttgccctgac gccaagtata aatggctgat caataacctg ccttaataaa 2574 0 ggatctggtg gttcagcata caagctgcgt tcaaacggaa gatagggggc agcaatatta 2580 0 ctctccattg gtctgcctat gccatcaaca agccgcccaa gtagtgcgtc tccaacacga 2586 0 atcttgaact catctccctg ataacttaac cactgaccac agtacatgcc ggaaacatgc 2592 0 tcaaaaggca acaagaaaac ctcatcttca tcaatagcga tcacctcggc taaacgttga 2598 0 ctgggttcta tcttataaaa ggcgccaata cgcgcttttg gtaaacgcgc cttaataatc 2604 0 gtcccgccga tattgataat cttgccttca tatctggtag acgaatttaa tgataatgcc 2610 0 ggcacagtgc tattgagcac tttctgaata cgtgggtatt tttccaatac agaatcatgc 2616 0 tctgaaatca tttaccgttc ctaatacttt aagttcgata ttattcccaa cctcctgaaa 2622 0 agagagcacg gggactgacg ggaacgaacc ttcaatcatt ttcttcacat agcgcctgat 2628 0 atctaaagcg gtcagaatga cgccgttccc cgttggattc atgatatttt ttaagaagcc 2634 0 aattatctgc tcagttcgct ccggtgagat attcagatac gaacctgatg acgtttgtct 2640 0 gatcgactct cgtagctcat tttcaatatc agagccaata agccaaacgt tcagaagtgt 2646 0 accgctaacg ctatagcgac ctaaaatatg ccgacgcagg gcaatacgaa cgtattcgca 2652 0 caagataacc acatcctttt cttttgttga ccaaaaaata agcgtctcaa agatagttct 2658 0 caggtctcta attgagacat tttcctctac gagacgttgt aggatgtcaa caattttgct 2664 0 caaaccaagc tggcgctgca gctctttcac aagctcgtta tattttctct ccatgatgtc 2670 0 catcaaataa cgcgtttctt gtacgccgat gaactctttg gcattagaca atacaagttt 2676 0 ctttagcaaa aacgttatct tatcatttgt tgttgcataa acatccatac ctgtaaggtg 2682 0 agcgagctgt tgattagtct tattcgtctt atatacgata gagttagtcg aaagcttttc 2688 0 ctggacaaat tcgaatgata tctctgcatg cccagcctca aaatagacag tatcatctat 2694 0 aagagtatct ttgtatattg actcttgata gagcaaaaat tctattgcgc tatcattatt 2700 0 tttaaccgga ttaacaataa tcttaggcaa tggaattcca ctttcctcaa agaaattcca 2706 0 acgcatgacc tcaatttgct gtgtaatgtc tgaactataa atattactac ttaagtttaa 2712 0 aatcaatggc tcagcgcccg gtgagatgtt ttggctatta gacaaatcag ctcccatagc 2718 0 atccttatta ttgccagttc caaatgttct tttcttctgt aatttccagg ctatccccaa 2724 0 caggcaaacc gccagaaata agaagaccaa tgcaggaaag cccggaataa tcgccattac 2730 0 gagcattagt gcggcactga ttaaaaaagg gcgactatta acagaaacct gttgaacaat 2736 0 atcacctgca aggttttctt ctttttcgct ttcaccgggc acacgagtaa caaccacgcc 2742 0 tgcggtgaca gaaataataa gcgcagggat ctgggcaacc aaagcatcac cgacagacaa 2748 0 tacagaaaac aggctaagtg ccgcactaaa tggcatgtca aattgccaca taccaatgag 2754 0 cacgccacca aaaaggttaa ctaaaacaat aatgatacca gcaatagcgt ccccttttac 2760 0 aaacttcatc gccccgtcca ttgaaccata aaactggctt tccttttgca ctcgggagcg 2766 0 aagaactttt gcctcaagcg ggtcaataac gcctgcgcgc atatcaccat caatactcat 2772 0 ttgctttcct ggcataccat caagggaaaa acgagcactc acttcagcaa cacgctcggc 2778 0 cccttttgta ataaccataa attgaacaat ggtgataata gtaaaaataa ccaggccaac 2784 0 aacaatatta ccgccaacaa caaagttacc gaaggagtaa ataatgtcac ccgcatcgtg 2790 0 atgcagcaga ataagtctgg ttgtactaac actgagcgac aggcgcatca acgtcgtaat 2796 0 caacaggatt gtggggaaag aagttagttc aagaggattt tttatataga ttgagagcat 2802 0 taataaaagt aaagctgtcg aaatattaat cgcgataatg atatccacca caactgttgg 2808 0 tagtggaata atcatcatca ttacagccat aaagaagaag agagccagaa taagatcgtg 2814 0 atatgactct gcttttttaa atatatttaa gagtttattc atgatgtcat cctgcgaacg 2820 0 cgctcaataa tctgcacatg ctgttgaaaa gtattcatta gaaaaaaaac atcgatattg 2826 0 gttaacaaac aacttaagca caatttatta tcgtagacaa aaatatgttc aatcactccc 2832 0 tgcgtacgct caggagcaag ggcactaaag aaagagaaaa atgcgttttc gttatactct 2838 0 aaagcaaacg taacaaaaac attattatca attatttcaa taaaaaaaga aaacccatta 2844 0 aaatcaattt caacacggtt atcaaataaa taaaaatcat ttcccaataa tcttaaaaac 2850 0 tcttcaacgt ttcttttaac taaaagattc atctgcaggc tctgaagtaa gtatacgtgt 2856 0 gaatattatt gcttgaaaaa gcgtattgga taatatatac agtatatgta ctttatgtac 2862 0 attgcaacta tttaaataat ataatagttg cctatgggat aatttggtta tttataacca 2868 0 ggtaaatgtc taaattagac aaaaggagaa agatcaatgg aagcagcaaa tttaagtcct 2874 0 tctggtgcag taatgccgct ggcgacctca ctcagtggaa ataactcagt ggatgagaag 2880 0 acaggagtga ttaaaccaga aaatggaaca aatcgcaccg ttagagttat agccggatta 2886 0 gcacttacca ctacggctct ggcagctcta ggtacaggta ttgcagcggc atgctcggag 2892 0 acgagcagca cagaatactt agccctgggt attacttctg gcgtactagg tactcttact 2898 0 gcggttggcg gtgcattagc gatgaaatat gcctaaccgg cccatcgcat aaataaaaga 2904 0 tagaggtaat ggatgtatta tgcccttgcc tctttcataa aaagaggcta acagtaaata 2910 0 tgaacaacat taatcaatcg gaaaacatta atattcaatt aaataaagcg ccccaaacaa 2916 0 atttcgttga tgagcatacc tcgttagcct cagccccctc tgcggcaggt gcggctcagt 2922 0 ttcttgatca attactccct aaaacagcgg gagtgtcttc tccagaacaa gtgttgattg 2928 0 aagaaattaa aaagagacat cttgcaacaa tgaacagcga tctcagtttc gatgctctat 2934 0 ctgcaggtgg gctctcgcca gaagacgtgc tcaccttaca aaagaatgtg ctcaacgcaa 2940 0 acgtcaacgt tgatgtcgta tctaagttag caagcctcct ttcaacatcg gttacaaaat 2946 0 tagtttcgat gcaataaaaa tgaaaaaaca cattaaaaac ctttttttat tggctgctat 2952 0 ttgtttgaca gtggcatgta aagagcaatt gtatacagga ttaacagaaa aagaagctaa 2958 0 tcagatgcaa gcactgttgc tatccaatga tgtcaatgtt tccaaagaaa tggacaaaag 2964 0 tggaaatatg acactcagtg tggaaaaaga ggattttgtt cgcgcaataa cgattttaaa 2970 0 taataacggc ttcccgaaaa agaaatttgc agatatcgag gttattttcc cacctagcca 2976 0 gttagtggca tcgccatcac aagaaaatgc aaaaatcaac tatctcaaag aacaagacat 2982 0 cgaaaggttg ctaagtaaaa tacctggtgt tatcgattgc agcgtttcat taaatgttaa 2988 0 caataacgaa agtcaaccct cctcagcagc cgttttagtc atcagctcgc cagaggttaa 2994 0 cttagcacca tcggtcattc agataaaaaa cctagttaag aatagtgttg acgatctcaa 3000 0 attagaaaat attagtgttg ttatcaagtc atcctcagga caggacgggt aatatgtatg 3006 0 aacaataata atggcatagc aaagaatgat tgtgactggc taacggccct tgattttgta 3012 0 aaggatgtca acggttcacc aacgcatctc actttttata tctaccaaaa aaatgctttc 3018 0 ttgcacgatt ttggaaacta ctgggttcta tatattgagc ttagtggtga ttttcgtcag 3024 0 gttccaacag atacatttat cagactctgc aatatcctgg ccgttagtaa cgaatataaa 3030 0 caaatgggta ttttcctgtc taataagaag tggtatcttt gccaaatttt tcataaagat 3036 0 aataatcatc gcgcaaacat gtcaaaagca ataatgcaac atactctcgc ctctttgctc 3042 0 gataagcaat ttgataaact agagcaatta tcttcatcgg atacaatgat gccgccaaca 3048 0 cacttgtttt ctgatatagg acgaattgtg taatgaaaaa aataagtttt tttattttta 3054 0 cagcactatt ttgctgcagt gcacaagctg ccccgtcctc tctggaaaaa agattaggca 3060 0 agagcgaata ttttattatt actaaaagtt ctccagtacg tgcaatcctt aatgactttg 3066 0 ctgctaacta cagcattcct gttttcatca gtagttccgt gaatgatgat ttctctggcg 3072 0 aaataaaaaa tgaaaaacct gtaaaagtac tggaaaaact gtccaaacta tatcatctca 3078 0 catggtatta tgatgagaac atcttgtata tttataaaac aaatgaaata tcaagaagta 3084 0 taattacacc aacatatctg gatattgact cactgctaaa atatctgagt gatacaatct 3090 0 cagtaaacaa aaactcttgc aatgtgagaa aaattacgac atttaactcg attgaagttc 3096 0 ggggtgttcc tgaatgtata aaatatatta catctttatc agaaagtctt gataaagagg 3102 0 cacagtctaa agccaaaaat aaagatgttg ttaaggtctt taaactgaac tatgcgtcag 3108 0 cgacagatat aacatacaaa taccgtgacc aaaatgttgt cgtcccaggt gttgtctcca 3114 0 ttctgaagac aatggcaagt aatggttcac ttcccagtac cggtaaaggt gccgtcgagc 3120 0 gaagcggtaa cctgtttgat aacagtgtaa cgatttccgc tgatccacgt cttaatgcag 3126 0 ttgttgtaaa agaccgcgaa ataacgatgg atatctatca gcaattaatt tctgagcttg 3132 0 atattgaaca aaggcaaatt gaaatttctg tctcaattat tgatgttgat gcaaacgatc 3138 0 ttcagcagct cggcgtaaac tggtccggta cgttaaatgc aggacaaggt acgattgcct 3144 0 ttaatagctc taccgcacag gctaatatca gctcttctgt gataagtaat gccagtaatt 3150 0 ttatgattag ggtgaatgcg ttacaacaga actcgaaagc taaaatactc tctcagcctt 3156 0 caattataac cttaaataat atgcaggcga ttcttgataa aaacgtaacg ttttatacaa 3162 0 aagtctccgg agaaaaggtg gcgtctctgg aaagtattac aagcggaaca ttgctgagag 3168 0 tgacaccacg tatacttgat gacagctcga atagccttac cggaaaacgt cgggaacgag 3174 0 ttcgtttgtt acttgatatt caggatggca atcaatcgac taaccaaagc aatgctcagg 3180 0 atgccagcag caccttacct gaagtacaaa attcagaaat gacaacagaa gcgacattaa 3186 0 gtgcaggaga aagtttatta cttggcggat ttatccaaga taaagaaagt tcaagtaaag 3192 0 atggtatacc gctgttaagc gacattcctg ttattggtag tttattctcc agtacggtaa 3198 0 aacaaaaaca tagtgttgtt cgactctttt taattaaagc aaccccgata aaatctgcat 3204 0 ctagcgaata ataaatgagg ctttatgagc aggaaattta gctctctaga ggatatttat 3210 0 gatttctacc aggatggtgg cacattagcg tcattaacaa atctgacaca acaagatctc 3216 0 aatgaccttc attcttatgc ctatacagca tatcaatctg gtgatgttat aaccgcaaga 3222 0 aatctattcc atttgctcac atatctggaa cactggaatt atgactacac cttatctctg 3228 0 ggcttatgtc atcagcgttt atcaaatcat gaagatgcac aactgtgttt cgcacgctgt 3234 0 gcaactttag ttatgcaaga tcccagggca tcttattatt ctggaattag ctacttactc 3240 0 gtcggaaata agaaaatggc caagaaagcc tttaaggctt gtttaatgtg gtgtaatgaa 3246 0 aaagaaaaat acactacata taaagaaaat attaaaaaat tgttaggtaa tacagagtaa 3252 0 aaactaccat cagctatacc aatccccagg ctgactgggg attttctatc ggaaataata 3258 0 aagctgctat agtgaagtgc tcccaaagtt gagcaccgac cactggtaga tttatctaca 3264 0 ggtgtggggt tattccatta accaggagtt tatgccctga actatcttct gctgtattta 3270 0 atatcatttc cgtttatgaa acaatcagta tatcttaact tagcattaga aatctgatct 3276 0 ttccaatcat ctatagctca gagtatattt gtcaggaaat gaccttcaaa ctttagccga 3282 0 gaaaaaggct taccctggaa aacaaaaccc ttaaatatag ctttattttt attcttctat 3288 0 aaaatatact caaaaaatta cgtctaactc tcctttttcc gcctcatgat catttcgttc 3294 0 cagatattag actgtcccac aataccatta ccaactcggt aggtttttct ttttggtccg 3300 0 gttgttccag gactttctat cggaaccgcc tcaaggttaa catcataaat gaaaatctca 3306 0 aggcgcttat aatgcaaatt accataacta acatatctga cacgaaatga aattttttct 3312 0 tttcttctcg atatataagt tataataaat gatgctctcc tcaggtttat accgaatgct 3318 0 tcggcaatat cattgcgaga aatccatttc tcctgcaatt tacaccaaag agaaaccaag 3324 0 atatacagag gttcaccatc gtaattcttt actgagtcag gaattacata gtcgccattt 3330 0 ttatttttag attccatttt ccatattctt tttatttgat aaataaatcg acataaaaaa 3336 0 catacataaa attattttaa ataaacttgt ggcattcctg tgtttttaat aactaatggt 3342 0 tctataaatt tggcataaac atcaacaaac aatttttcat ttcctcttac atggcaatgt 3348 0 aatgtgagat tattatcatt actcagtact tttttaggga taactaattg ataatcttgt 3354 0 tcaatgttta gcaccgaggg aatttcgtaa ttatatcgat ggacatgaag tatgatgtcc 3360 0 tcatcttcag agaggacccc ctgatacaca gaagcaatat cgccgccagt gatcatattt 3366 0 ccatttttaa tcagtatacc ttccccacag gagtcttcat tgctaataaa tataatgcta 3372 0 tagatgccat ccttcataat cataactcac tcagtttcat actaacctca ctcctttcaa 3378 0 tttgttctat ccataagcaa tatcaagaat aatggagacc tttctttttc tccagattgc 3384 0 aatgtaatat atcattaaat atactcatgt ttcaacctgc tgtttccctg gttaacatat 3390 0 gtaatttctg attaataata ttgagtaaca acgtaaaaat gaaaaaaata atactgagca 3396 0 tcattctcat ttcaaattac tgttatgctt ccgattgttt tgaaattaca ggaaaagcat 3402 0 ataacataga tccattaata ttaaaagcaa ttgcatggaa tgaatcaaaa tgcaaaagcg 3408 0 gaataaaaag caaaacaaac aaaaacggaa cgtatgatat aggtataatg caaattaatt 3414 0 catctcattt agatttatta agcaaattta atatatctga agatgattta ttgaatgatg 3420 0 cctgtataaa catatctgtt gctggttata tcttagcctc taacataaaa tccagaggga 3426 0 atacatggga tgcagttggt gcgtataatg caggttactt taatacacca aatgcagtag 3432 0 aactcagaag gcaatacgca atgaaaatat ataaaacata taataaatta aagaataatg 3438 0 agcaaattat cgattaataa tcaaggtcta tcgcaatacg aatcaattgt gccacaggtt 3444 0 caaaaaagtc ttctgttata tattgtcctt tatgtatatt cttatagaga gttcttgcta 3450 0 aaggaatatc ttcaatcact ggaatatcat agagttcagc cagtttaatg atctgtagag 3456 0 ctttggcatc ttttcctgtt tcaataacta aaggtaatgg agtctcccca agtttatagt 3462 0 ataggcaaat cgcaatgtga gtcgggtttt taacaataac ggttgatttt ttgatgttat 3468 0 tagccaaact tccactttgt atctcggaat gaaggcgacg gcgctcccct ttaatttcag 3474 0 ggttaccatc agtatccttg gcttctcgtt tcacctcatc tttactcatt ttcattttct 3480 0 tcagtccctc atgcttctgg aaccagaaat caaatactga aaagagtaga tatccgaata 3486 0 gcacgccttt ccataaaaga aaaacaaaaa aggcaacaac gacaagagct tgatatgcgt 3492 0 tcagtcctgt gaaattagca aactcatttg catatgaatg ccccataaaa taaaaaatga 3498 0 gaacaattat cactaactta aatactgatt taagtagctc aaaaatgctc tttacagaaa 3504 0 aaatattttt caggttattt tttacactaa tcttctgagc cgatggtttt attttttcaa 3510 0 ccgcaaagat gaatcctatt tgtgatacac cagtcgtaac agttccaaca aagacaatca 3516 0 aagaaattgg caaaatatat aataaaaata tatttaatac cgcacctaat atttctcgaa 3522 0 tggcatacaa aaacggtcta tttagcgagt ctattgtcgt attaactaat ccaactatat 3528 0 caacaaaaaa actcatgcca tataaagaaa aaaatgaaaa taagattaat gactgcactg 3534 0 cagccattac ctcttcactt tttgttacat cgcccttctt ttttagatcc cttagttttt 3540 0 tgggtgtggg cttttctgtt ttttcactca ttaatcatgc tcggtaacga tctatcaatt 3546 0 atgtcagaat gaatatttgc cgtaataaaa tcaggaaaaa catgaataac taatagcaat 3552 0 ataaagattg ctatcaaact ttttactggc agtgataatg tgaatacgtt tagctgaggt 3558 0 gctgttttgt taagaaaccc aaaccccata tcacataaga atataccgat aatcatggga 3564 0 actgaaaatg ataacatcag tttaataaat gaatcccata gagaaaacaa aaaatctatt 3570 0 aaagcacgat tgaatgcaat atcggcttgt aatggtaata tctcgtagga taaatatagc 3576 0 ttatctagga tgctttgtat cccaccatga ataacaaaga tcacagagat aaattggtac 3582 0 aagataacgc cagtgataga agatgaatca cttatggacg ggttaaaaat tgaagatatt 3588 0 gttgagcctc ttagagtatc aataatctgt ccagccgcat ctattgccca aaaaagaata 3594 0 gtaaatgata acccaatgaa aaaaccaata cttatttctt ttagcgctat tcctgtcaac 3600 0 tgaaagattc cagatggcaa tttttccgaa aatgtatagt tctctactat gatcggaagc 3606 0 gtaaacgcaa tcataattga gttgcgaata aagttactga gtaaaacacc tgttgaaaat 3612 0 attggtagga taataaacat ccccagcggc ctgagtatac aataaaatga tgatactatg 3618 0 accgtcatta tctcattcat tagccgttca ccttcggaat catttcaaat attatcgacg 3624 0 agaagttgat gattgttgtt cccatccagt gataagtcag ggcaagcgta gcaaacactg 3630 0 ctattatttt tagcaaaaaa ggcaatgttt gatcctgtaa ctgcgttata gcctggacca 3636 0 gactaataat aataccgata acagaggccg ctatgactgt aggcaatgag aggataaata 3642 0 ttatccagaa cgtttgcaca cataattgaa caaaatatcc agtatccatc aattcaccac 3648 0 caacagaaat tcgaataatt tttgccagcc tccaacaaga atgaataata agatcttaaa 3654 0 aggaatcgaa attgttactg gcgataccat catcataccc aaggccaata agatattgga 3660 0 aatgatcaaa tctatcgcaa taaagggtaa atagagcaaa aaacctatct tgaatgcagc 3666 0 ttcaagctgc cccatcgtga aagccggtaa cagtataaat agagagtctt tttttaagat 3672 0 agtttcatta cccaattttt tttgagctgc acgttcaaaa aactctacat tgtctttctc 3678 0 tgtatttttt tctaaaaaac cgcgatatgg tgataatatt ttctcatcaa ctttttgaaa 3684 0 aaaatcagag tcggtataat tgattggttc ctgagaaata ttatcattta tctgtaatat 3690 0 tatcggagac ataataaaca ttgtcagtat caaagacact gatgttagcg ccatgtttgg 3696 0 tggtacctgt tgaatgccta atgcgttctt caatatcccc agtacaatag aaattttcag 3702 0 gaatgaagta ccaataccaa caaatattgg cagtaatgat aacagaaaaa atacaataat 3708 0 taaaaatatt ggctgtgagc caatggtcat taattgagac atatcatcat tcctgaataa 3714 0 tgctaagata attatcttta aatgaattca ataaaatact tatttgctct aatgggtcta 3720 0 aagttattct aatatattca ttttctatta taattttatt atgcggtgtg tttgcatcat 3726 0 taataagctg tatattgttg gcctcgccag gatcaagttt aatgtctggg tttttagtga 3732 0 tcttaatagc tccgacaata ttgttattag atagagtttc ccttacaact tcattaagta 3738 0 aatcatccca attaattctt gatgatgtat ctaaagaatg taatgcatta gtcagtgaca 3744 0 aatgaatctt attcattatg tcctgcatta agaccaactc gatagcctgg atatctttaa 3750 0 cccattttat cgattggtta acctctttat ctaattttat tttattattt tttcgaatcc 3756 0 tttctctcat tagaatcatt tttctggcaa ttttttttct ggattctgtc tttaattctt 3762 0 tcgatttcct cctcgccctc agtaaatgtt catatgtttt ttttcgagcc agtttgataa 3768 0 tatcatcaga ttgaataatt tcctgtaact tatcctctgg tatgatatct tctgtaagca 3774 0 ctaaatcaat ttttatattt ttaaattcat aaagtttcat aaggcaataa aattttatta 3780 0 agtctgttaa gaaataaatc attaatatga gttggtttta tttctccact tttcggcaaa 3786 0 agatatttga ctatggtcca taaaggatta tcagcaaata gccactccaa atttcctgca 3792 0 ccgtatttta ttaactcagc acaaaaccgt tcttcaccat attctggttt acattgccct 3798 0 ccctgccaat agaatgataa ctgcttcaca ttttgatatc ctatctctct aatcagagtt 3804 0 tctcgatata atcgtgagaa aatataatca gggcattgaa tgtcaaataa tgcactactt 3810 0 agagcaagca atcttatttt cccaattgac tgatataaaa aaccttcctt atttatgtca 3816 0 gataattcca caccagaaat tttatcatgt atttcctgac gcaatatctt attgagttga 3822 0 ttacgagtag aactagtttc tcttaaacgc cgaaaactga cctgattgac accggttaaa 3828 0 tcacctagcc attcatcatg aaccatcatg attggataat taattaattt ataatagtta 3834 0 tagtctattt tattaaaaat tgtcatacta tttttctatt atttctattc cgttgattca 3840 0 ttgttgattg gcttttagat cttgctggac tcagtgtctc tattagtttt tcaatcttac 3846 0 ttagggcaga atcatataat tttcgctctt caccatatgt gtacccctca attaatttgt 3852 0 ttaatttttc tgccgcctga ggatctgttt ttgctttttc acttaactca ttaacgcttt 3858 0 cttttacgac atcaaattcg gcgattattt tttttatcgc ctcaatttct gatcttattt 3864 0 ttttatctaa tagttcttta tttcttgttt ggctcacaat actcatcctc tatttattat 3870 0 taatcctgat tcgcattatc tctatagtcc taattgccgc atcacacgca atgagcagtt 3876 0 cctttgcttc atcgtaggta actttatcca aagggtgttt cattttttca tggatttcgt 3882 0 tctttttgtc gtttattttt tcaataaaaa catttgcggc ttctttattt tttattattt 3888 0 catcttccag ctcagttatc gttatcattt aattatttca tgttaaatat ttttcagcgg 3894 0 tattatttct tcttcagtgt ccttcacaag aaaatcttct ttcttcattc cattcaacag 3900 0 tgcttcttta agccagcgtg gctgtcggcc tacgcccgac caggtctgcc cttcttcatt 3906 0 gcggtagtaa acacctttcg atgagttccg gcgagcgagt ccatcatcag gcacattagt 3912 0 atatcccagc tcttgtaagg ttatattgta ataagtaatc tgcttctgaa tcgactcaat 3918 0 tacactttga acttcctgct ctcgcagtcg ctttgcttcc tgctgtagaa ctgcaatttg 3924 0 ctctataagc tgaatgtatg gacttgttgt atgtgaatta ttttccatat tcataataaa 3930 0 taatctccgc atgctttaat attttaagct attagcgacc ttatcaggaa ggaccaacaa 3936 0 ttaatcaaat gatataaatt atgtgagata acgtttatct atcaaattag gacacatcta 3942 0 tttcatcaaa caaccacctt aaaatgttat tattctcttt tttctaatgt gtaaaataca 3948 0 ttatcattaa atgtcaacaa aaaaatcata tatttttaaa atccatttaa aatcaatgat 3954 0 atagaagaaa atcatctcgt taacaaacga ctttaataat tgcatttcca tttagttaag 3960 0 cgtttctctt tataagatag atctcattgc ataaacaaat aaaacagaat aaaaaccaag 3966 0 ctgaaccgtt tcactatact ctacttaatt cgagttacag gaaggcggca agcgagtgaa 3972 0 tccccaggag cttacataag taagtgattg gggtaagcga acgcagtcgc agcacatgca 3978 0 acttgaagta tgacgagtat atatatctat tagctgtttc ccggacataa gctacagcca 3984 0 gcactaacct ggaacgggtg cattataaaa aggaacaagg gacaaatagc tgaacagtaa 3990 0 ccgcgttagt ctcttcccgc ataaccgtac cattcgtatt aagaagtatt gtccatatcc 3996 0 attcggcgaa agaggatctg ccatacatca agtccgtttt acttggcatc agatcatcgc 4002 0 cgtcattaac tctgttaaag tcggacaaac gattagcaag atctgtgatt caaaagtgct 4008 0 tagcgctaag gtgggactgg ttacagattc attaaccctg ttctttgtcg cacctatcga 4014 0 tcggtgtaat gccacaacag gtttatgtta atcagaacaa tgcgcccctc tataaagaga 4020 0 attctttgat aaggcaactt gaaaagggaa agctaactga tatcaatgta ccactttagt 4026 0 aatcatcaca ttatatacag gccaaaataa gtttcctgaa agccagtatc tctaaatcaa 4032 0 tcattaatga tatattttat cgtcacaata aaaaattatc taaattctat tacttatgta 4038 0 aataagtaca accttttcat agacacaaaa actatggctg acgcatcact tgcaatcaat 4044 0 tatccatcat tagattaata ttttcactta tttttcagaa ggtaaaaata actttctatg 4050 0 cgtttaaaac acccgctata aatatcttgt atattattga cactatatga tgctatatga 4056 0 tacttgttgc caaattgttc attacaaacc agataggaga atctctcatg ataaatggac 4062 0 ttaataatga ctccgcatct ttagttttag atgctgcaat gaaagttaat tctgggttta 4068 0 aaaaaagctg ggatgagatg tcatgcgctg aaaagttatt taaagtactt agttttggtt 4074 0 tatggaatcc aacgtacagt cgtagtgaaa gacaatcatt tcaagagttg ttaaccgttt 4080 0 tagagcctgt atatccactt cccaatgaat taggcagagt atctgctcgt ttttcagatg 4086 0 gttcatcctt aagaatttcc gtcactaaca gcgaacttgt tgaagccgag attcgcacag 4092 0 caaataatga aaagattact gtgctcctgg agtcaaacga acaaaatagg ttattacaat 4098 0 ctttacccat cgatcgccac atgccataca ttcaggttca tcgtgcctta tctgagatgg 4104 0 acctgactga tactacctca atgcgcaatc tacttggttt tacgtcaaaa ctatcaacaa 4110 0 ccttgattcc tcataatgct caaacagatc cgctttccgg gcctacacca ttcagctcta 4116 0 tctttatgga tacatgtcga ggactcggca atgcaaagct ttcactcaat ggtgttgata 4122 0 tacctgcaaa tgcacaaaaa ttgcttcgcg atgcactagg acttaaagac acacattcat 4128 0 caccaacccg gaatgttata gatcatggta tttctcgcca tgatgcagag caaatagcaa 4134 0 gagaaagcag cggcagtgat aaacagaaag ctgaagttgt ggaattttta tgccatccag 4140 0 aagcagcaac ggccatatgc tcggctttct atcaatcttt caatgtgcca gccttaacgt 4146 0 tgacacatga aaggatctct aaagccagtg aatacaatgc ggaaagatca ttagatacac 4152 0 ctaacgcttg cattaacatc agtatctctc aatcatcaga tggaaacatt tatgttacca 4158 0 gccatactgg ggttctgata atggcgccag aagaccgccc caacgagatg ggcatgttga 4164 0 cgaacaggac ttcttatgaa gtgccgcaag gtgtgaaatg tataatcgat gaaatggtaa 4170 0 gtgcgctaca accaaggtat gccgcatctg aaacgtactt acaaaacact taaaataaaa 4176 0 ctttattaat caaaactaat aatagaaacc acacccataa ttattaacaa tttattccga 4182 0 agttaatcac aattaaacaa agatatttat tctgcaaaca atttacagca aatagagaaa 4188 0 atgaaaagaa aaccattgat tgcatttttc atcgcgatat ttattgcact aaccatatta 4194 0 atattatttc catttaattg tacttacaaa aaatcacctc aagaacactc actttcattt 4200 0 ataaaacaat taccaaatac ggtgaactta tcatctctta cttataataa agaggatgat 4206 0 ttcctgtatg ccacccagaa tagccctgca cagctactta aaataaccaa aagtggcgac 4212 0 atcatggaca gagccccact gccttttatc tctgatgccg aaacaattga acacatacaa 4218 0 gggaacattt ttgctgcagt agacgaaaag acttctgaac tattcttttt tacagttaca 4224 0 aaagatatgc atatctcctt tcgaaataaa attcagttag aaaaattcaa taaaaagaat 4230 0 agagggtttg aagggctggc atggaaagca gatgatcgga tgctgtttgt cgcaaaagaa 4236 0 agacgcccaa gtaaaatatt tatatatcaa ctttctccag acctgctgag tgtaaagcaa 4242 0 gcaactattc cagaggcact aaatgatata cgtgttaacg atatatccgg cctggccttt 4248 0 aataatgaaa gtctgatgat tctgtccgat gaatcgcgta aattactcaa gtttaacctg 4254 0 acagagatgt ctttcattga gatgcttgac ctgacaaaag gaaatcattc tctgaccagt 4260 0 gatttgcccc aacctgaagg aattgtaact ctgcctgatg aaagcattta tgttgccagt 4266 0 gaacctgata tcctcgcgaa atttgtccct aataagtaag tctgtcactg gccttattat 4272 0 ttatcgacca aacctggcaa tctcataaag ttataaaaat acgagtataa tttcacgcta 4278 0 aataaacaca ttaatagttg aaaaggatat cagttattat caaccagaat cttactcagt 4284 0 ctattagtat tatcagactt atattagatc ctacaatata tttaatttgt atgcagaata 4290 0 gagtgttcac accacatctg gtatagaaaa gcacaggcta gcaaaaacct gaataacccc 4296 0 gtacttacgg agttattcag gttaaaaata tccataacat cacttctgat ttttattgct 4302 0 tacgacggat ataatttctc tggtcagcta ctaatatcat catgctcacg cgtttaatca 4308 0 aactcgtgtt tctcaaacgg acatcgcggg acaatcttct gcttctcccg gcgcattttt 4314 0 taccaccttc gctacctgca ttttgagcgg aagatccgct tttttctggc ccccgcacat 4320 0 atgcaagtcc agttttaaat ttatccttta tttcattctg aaacaaactg ctcataattt 4326 0 tctccagtgg aacctgcatc tcagggagac atcactacag aatacttccc cttatgcact 4332 0 gatttaattt tggtcattta gaataacggc ctgtaaagtc tcaatgcaac agatgggtaa 4338 0 cgctattatg aggatcctcg tcagtaaatt actggcaagg cactccgata aataagaata 4344 0 ggttccgcaa 4345 0 <210> 817 <211> 394 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(196..1377) <400> 817 Met Ala Leu Thr Asp Val Lys Val Lys Thr Ala Lys Pro Lys Glu Arg 1 5 10 15 Pro Tyr Lys Leu Ala Asp Gly Gly Gly Met Tyr Leu Leu Ile Asn Ala 20 25 30 Asn Gly Ser Lys Tyr Trp Arg Met Lys Tyr Arg Phe Ala Gly Lys Glu 35 40 45 Lys Met Leu Ser Ile Gly Val Tyr Pro Asp Val Thr Leu Ala Asp Ala 50 55 60 Arg Glu Lys Arg Ser Glu Ala Arg Lys Ile Leu Ala Ala Gly Gly Asp 65 70 75 80 Pro Gly Glu Ala Lys Lys Glu Glu Lys Ile Ala Leu Gln Met Ser Leu 85 90 95 Lys Asn Thr Phe Glu Ala Val Ala Arg Glu Trp His Gln Thr Lys Ala 100 105 110 Asp Arg Trp Ser Leu Arg Tyr Arg Asp Glu Ile Ile Asp Thr Phe Glu 115 120 125 Lys Asp Ile Phe Pro Tyr Ile Gly Lys Arg Pro Ile Ala Glu Ile Lys 130 135 140 Pro Met Glu Leu Leu Glu Ala Leu Arg Lys Met Glu Lys Arg Gly Ala 145 150 155 160 Leu Glu Lys Met Arg Lys Val Arg Gln Arg Cys Gly Glu Val Phe Arg 165 170 175 Tyr Ala Ile Val Thr Gly Arg Ala Asp Tyr Asn Pro Ala Pro Asp Leu 180 185 190 Ala Ser Ala Leu Ala Thr Pro Lys Lys Val His Phe Pro Phe Leu Thr 195 200 205 Ala Asn Glu Leu Pro His Phe Leu Thr Asp Leu Ala Gly Tyr Thr Gly 210 215 220 Ser Ile Ile Thr Lys Thr Ala Thr Gln Ile Ile Met Leu Thr Gly Val 225 230 235 240 Arg Thr Gln Glu Leu Arg Phe Ala His Trp Glu Asp Ile Asp Phe Glu 245 250 255 Ala Lys Leu Trp Glu Ile Pro Ala Glu Val Met Lys Met Lys Arg Pro 260 265 270 His Ile Val Pro Pro Ser Glu Gln Val Ile Ala Leu Phe Lys Gln Leu 275 280 285 Glu Pro Ile Ser Lys His His Pro Leu Val Phe Ile Gly Arg Asn Asp 290 295 300 Pro Arg Lys Pro Ile Ser Lys Glu Ser Ile Asn Gln Val Ile Glu Leu 305 310 315 320 Leu Gly Tyr Lys Gly Arg Leu Thr Gly His Gly Phe Arg His Thr Met 325 330 335 Ser Thr Ile Leu His Glu Gln Gly Phe Asn Ser Ala Trp Ile Glu Met 340 345 350 Gln Leu Ala His Val Asp Lys Asn Ser Ile Arg Gly Thr Tyr Asn His 355 360 365 Ala Gln Tyr Leu Asp Gly Arg Arg Glu Met Met Gln Trp Tyr Ala Asp 370 375 380 Tyr Ile Asp Ser Leu Ser Glu Leu Ala * 385 390 <210> 818 <211> 117 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1476..1826) <400> 818 Val Ile Ser Ser Pro Gln His Lys Thr Gly Asp Leu Met Asn Lys Lys 1 5 10 15 Thr Lys Arg Thr Phe Thr Pro Glu Phe Arg Leu Glu Cys Ala Gln Leu 20 25 30 Ile Val Asp Lys Gly Tyr Ser Tyr Arg Gln Ala Ser Glu Ala Met Asn 35 40 45 Val Gly Ser Thr Thr Leu Glu Ser Trp Val Arg Gln Leu Arg Arg Glu 50 55 60 Arg Gln Gly Ile Ala Pro Ser Ala Thr Pro Ile Thr Pro Asp Gln Gln 65 70 75 80 Arg Ile Arg Glu Leu Glu Lys Gln Val Arg Arg Leu Glu Glu His Asn 85 90 95 Thr Ile Leu Lys Lys Ala Thr Thr Ala Leu Leu Met Ser Asp Ser Leu 100 105 110 Asn Gly Ser Arg * 115 <210> 819 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1839..2021) <400> 819 Val Thr Ala Thr Gln Leu Ser Ala Ser Val Leu Leu Trp Lys Tyr Thr 1 5 10 15 Ala Ala Val Thr Ser Thr Gly Glu Asn Asp Ala Ile Arg Leu Ile Arg 20 25 30 Arg Glu Ser Gly Cys Ala Ala Lys Tyr Ala Gly Arg Gly Thr Lys Val 35 40 45 Gly Ala Leu Arg Gly Arg Ala Arg Trp Leu Lys Cys * 50 55 60 <210> 820 <211> 218 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2039..2692) <400> 820 Met Ser Arg Tyr Arg Ala Gly Arg Leu Met Lys Tyr Leu Asn Leu Ser 1 5 10 15 Ser Cys Gln Pro Gly Lys His Gln Tyr Lys Asn Ala Arg Gln Glu His 20 25 30 Thr Cys Leu Pro Asn Leu Leu Glu Arg Gln Phe Ala Val Pro Glu Pro 35 40 45 Asp Arg Val Trp Cys Gly Asp Ile Thr Tyr Ile Trp Ala Gly Asn Arg 50 55 60 Trp Cys Tyr Leu Ala Val Val Met Asp Leu Phe Ala Arg Arg Val Ile 65 70 75 80 Gly Trp Ser Leu Ser Ala Asn Ala Asp Thr Ala Leu Ile Ser Ser Ala 85 90 95 Leu Arg Met Ala Tyr Glu Val Arg Gly Gln Pro Arg Asp Val Met Phe 100 105 110 His Ser Asp Gln Gly Ser Gln Tyr Thr Gly Leu Lys Tyr Gln Gln Leu 115 120 125 Leu Trp Arg Tyr Arg Ile Lys Gln Ser Val Ser Arg Arg Gly Asn Cys 130 135 140 Trp Asp Asn Ser Pro Met Glu Arg Phe Phe Arg Ser Leu Lys Thr Glu 145 150 155 160 Trp Val Pro Thr Asp Gly Tyr Thr Gly Lys Asp Val Ala Arg Gln Gln 165 170 175 Ile Ser Ser Tyr Ile Leu Asn Tyr Tyr Asn Ser Val Arg Pro His His 180 185 190 Tyr Asn Gly Gly Leu Thr Pro Glu Glu Ser Glu Asn Arg Tyr His Phe 195 200 205 Tyr Cys Lys Thr Val Ala Ser Ile Thr * 210 215 <210> 821 <211> 48 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2710..2853) <400> 821 Met Leu Thr Ser Gly Glu Leu Asn Pro Arg His Gln His Thr Val Thr 1 5 10 15 Leu Tyr Ala Lys Gly Leu Thr Cys Lys Ala Asp Thr Leu Gly Ser Arg 20 25 30 Gly Tyr Val Tyr Met Ala Val Tyr Pro Thr Pro Glu Thr Lys Lys * 35 40 45 <210> 822 <211> 125 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2943..3317) <400> 822 Met Lys Thr Leu Pro Asp Thr His Val Arg Glu Ala Ser Arg Cys Pro 1 5 10 15 Ser Pro Ile Thr Ile Trp Gln Thr Leu Leu Gly Arg Leu Leu Asp Gln 20 25 30 His Tyr Gly Leu Thr Leu Asn Asp Thr Pro Phe Ala Asp Glu Arg Val 35 40 45 Ile Glu Gln His Ile Glu Ala Gly Ile Ser Leu Cys Asp Ala Val Asn 50 55 60 Phe Leu Val Glu Lys Tyr Val Leu Val Arg Thr Asp Gln Pro Gly Phe 65 70 75 80 Ser Ala Cys Thr Arg Ser Gln Leu Ile Asn Ser Ile Asp Ile Leu Arg 85 90 95 Ala Arg Arg Ala Thr Gly Leu Met Thr Arg Asp Asn Tyr Arg Thr Val 100 105 110 Asn Asn Ile Thr Leu Gly Lys His Pro Glu Ala Lys * 115 120 <210> 823 <211> 164 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3314..3805) <400> 823 Met Met Lys Leu Ala Leu Thr Leu Glu Ala Asp Ser Val Asn Val Gln 1 5 10 15 Ala Leu Asn Met Gly Arg Ile Val Val Asp Ile Asp Gly Val Asn Leu 20 25 30 Ala Glu Leu Ile Asn Met Val Cys Asp Asn Gly Tyr Ser Leu Arg Val 35 40 45 Val Asp Glu Ser Asp Arg Thr Ser Ala Asp Cys Thr Pro Pro Phe Thr 50 55 60 Ala Leu Thr Gly Ile Arg Cys Ser Thr Ala His Ile Thr Glu Thr Asp 65 70 75 80 Asn Ala Trp Leu Tyr Ser Leu Ser His Gln Thr Ser Asp Phe Gly Glu 85 90 95 Ser Glu Trp Ile His Phe Thr Gly Asn Gly Tyr Leu Leu Arg Thr Asp 100 105 110 Ala Trp Ser Tyr Pro Val Leu Arg Leu Lys Arg Leu Gly Leu Ser Lys 115 120 125 Thr Phe Arg Arg Leu Val Val Thr Leu Ile Arg Arg Tyr Gly Val Ser 130 135 140 Leu Ile His Leu Asp Ala Ser Ala Gly Cys Leu Pro Gly Leu Pro Thr 145 150 155 160 Phe Asn Trp * <210> 824 <211> 66 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3817..4014) <400> 824 Met Thr Ser Leu Thr Pro Glu Ala Ala Leu Asp Ile Leu Ile Ala Trp 1 5 10 15 Leu Gln Asp Asn Ile Asp Ser Glu Ser Gly Ile Ile Phe Asp Asn Asp 20 25 30 Glu Asp Lys Thr Asp Ser Ala Ala Leu Leu Pro Cys Ile Glu Gln Val 35 40 45 Arg Glu Asp Val Arg Thr Leu Arg Gln Leu Gln Leu Leu Gln Gln Asn 50 55 60 Arg * 65 <210> 825 <211> 114 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4099..4440) <400> 825 Met Ser Gly Ile Ile Ile Ser Arg Pro Glu Val Asp Thr Gly His Thr 1 5 10 15 Asp Val Ile Cys Ser Thr Ser Ile Arg His Val Val Thr Val Arg Asn 20 25 30 Ala Ala Leu Gln Gln Thr Glu Thr Leu Ile Arg Gln Leu Ala Glu Ile 35 40 45 Ser Val Leu Thr Ala Ala Asp Ile Gly Gly Lys Thr Ala Leu Asp Arg 50 55 60 Ala Met Lys Gln Asp Phe His Cys Gly Cys Trp Leu Met Glu Lys Pro 65 70 75 80 Glu Thr Ala Met Lys Ala Ile Thr Arg Asn Leu Asp Cys Glu Ile Trp 85 90 95 Arg Asp Leu Met Gln Arg Ser Gly Met Leu Ser Leu Met Asp Ala Gln 100 105 110 Gly * <210> 826 <211> 48 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4501..4644) <400> 826 Met Asn Ala Phe Lys Gln Leu His Gln Ser Lys Asp Glu Val Phe Glu 1 5 10 15 Arg Gly Val Ile Asn Val Phe Arg Gly Pro Asn Gly Ile Thr Lys Pro 20 25 30 Ile Pro Pro Val Asn Ser Ala Val Lys Leu Ser Ser Thr Thr Trp * 35 40 45 <210> 827 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4641..4826) <400> 827 Val Arg Trp Asp Arg Trp Arg Phe His Leu Ile Ser Gly Met Gln Ala 1 5 10 15 Asp Arg Leu Ala Asp Leu Glu Arg Met Leu His Leu Leu Ser Gly Lys 20 25 30 Pro Leu Pro Asn Asn Arg Gly Asn Ile Thr Ile Asn Leu Asp Asp His 35 40 45 Leu Gln Ser Val Gln Gly Lys Glu Arg Tyr Glu Asp Lys * 50 55 60 <210> 828 <211> 134 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5196..5597) <400> 828 Val Gly Thr Lys Val Ser Asp Met Gln Lys Asn Val Thr Pro Gly Arg 1 5 10 15 Arg Lys Gly Cys Pro Asn Tyr Pro Pro Glu Phe Lys Gln Gln Leu Val 20 25 30 Ala Ala Ser Cys Glu Pro Gly Ile Ser Ile Ser Lys Leu Ala Leu Glu 35 40 45 Asn Gly Ile Asn Ala Asn Leu Leu Phe Lys Trp Arg Gln Gln Trp Arg 50 55 60 Glu Gly Lys Leu Leu Leu Pro Ser Ser Glu Ser Pro Gln Leu Leu Pro 65 70 75 80 Val Thr Leu Asp Ala Ala Ala Glu Gln Pro Glu Ser Leu Ala Glu Asp 85 90 95 Pro Glu Thr Leu Ser Ile Ser Cys Glu Val Thr Phe Arg His Gly Thr 100 105 110 Leu Arg Phe Asn Gly Asn Val Ser Glu Lys Leu Leu Thr Leu Leu Ile 115 120 125 Gln Glu Leu Lys Arg * 130 <210> 829 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5594..5941) <400> 829 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Asp Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 830 <211> 513 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5991..7529) <400> 830 Met Asn Asp Ile Ser Ser Asp Asp Ile Phe Leu Leu Lys Gln Arg Leu 1 5 10 15 Ala Glu Gln Glu Ala Leu Ile His Ala Leu Gln Glu Lys Leu Ser Asn 20 25 30 Arg Glu Arg Glu Ile Asp His Leu Gln Ala Gln Leu Asp Lys Leu Arg 35 40 45 Arg Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala 50 55 60 Gln Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu 65 70 75 80 Thr Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr 85 90 95 Arg Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg 100 105 110 Leu Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser 115 120 125 Tyr Leu Gly Glu Asp Thr Ala Glu Gln Leu Glu Leu Met Arg Ser Ala 130 135 140 Phe Arg Val Ile Arg Thr Val Arg Glu Lys His Ala Cys Thr Gln Cys 145 150 155 160 Asp Ala Ile Val Gln Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly 165 170 175 Ile Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Ser Lys Tyr Ala 180 185 190 Glu His Thr Pro Leu Tyr Arg Gln Ser Glu Ile Tyr Gly Arg Gln Gly 195 200 205 Val Glu Leu Arg Arg Ser Leu Leu Ser Gly Trp Val Asp Ala Cys Cys 210 215 220 Arg Leu Leu Ser Pro Leu Glu Glu Ala Leu His Gly Tyr Val Met Thr 225 230 235 240 Asp Gly Lys Leu His Ala Asp Asp Thr Pro Val Gln Val Leu Leu Pro 245 250 255 Gly Asn Lys Lys Thr Lys Thr Gly Arg Leu Trp Ala Tyr Val Arg Asp 260 265 270 Asp Arg Asn Ala Gly Ser Ala Leu Ala Pro Ala Val Trp Phe Ala Tyr 275 280 285 Ser Pro Asp Arg Lys Gly Ile His Pro Gln Thr His Leu Ala Cys Phe 290 295 300 Ser Gly Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr 305 310 315 320 Arg Asn Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg 325 330 335 Lys Ile His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu 340 345 350 Ala Leu Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg 355 360 365 Gly Met Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys 370 375 380 Pro Leu Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr 385 390 395 400 Leu Ser Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn 405 410 415 Gln Trp Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile 420 425 430 Asp Asn Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg 435 440 445 Lys Asn Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala 450 455 460 Pro Leu Tyr Ser Leu Ile Gly Thr Cys Lys Leu Asn Asp Val Asp Pro 465 470 475 480 Glu Ser Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val 485 490 495 Asn Arg Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu 500 505 510 * <210> 831 <211> 78 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7726..7959) <400> 831 Met Val Phe Asn Ser Ile Phe Val Ile Gln Gly Gly Ile Glu Asp Ile 1 5 10 15 Arg Lys Asn Leu Lys Ile Gly Thr Asp Arg Lys Leu Arg Gly Gln Gln 20 25 30 Lys Arg Met Val Thr Pro Gly Asn Ala Thr Pro Thr Ser Arg Ala Asn 35 40 45 Pro Pro Leu Gln Ser Trp Phe Ala Val Leu His Thr Arg Leu Pro Gly 50 55 60 Tyr Thr Gly Ala Val Trp Ser Glu Asn Ile His Ala Ala * 65 70 75 <210> 832 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7844..7999) <400> 832 Met Gln Arg Pro Pro Val Gly Leu Ile His His Ser Asn Arg Gly Ser 1 5 10 15 Gln Tyr Cys Thr His Asp Tyr Arg Ala Ile Gln Glu Arg Phe Gly Leu 20 25 30 Lys Thr Ser Met Pro Arg Lys Gly Asn Arg Tyr Asp Asn Thr Ser Met 35 40 45 Lys Asn Leu * 50 <210> 833 <211> 249 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8394..9140) <400> 833 Met Leu Asn Gly Ile Ser Asn Ala Ala Ser Thr Leu Gly Arg Gln Leu 1 5 10 15 Val Gly Ile Ala Ser Arg Val Ser Ser Ala Gly Gly Thr Gly Phe Ser 20 25 30 Val Ala Pro Gln Ala Val Arg Leu Thr Pro Val Lys Val His Ser Pro 35 40 45 Phe Ser Pro Gly Ser Ser Asn Val Asn Ala Arg Thr Ile Phe Asn Val 50 55 60 Ser Ser Gln Val Thr Ser Phe Thr Pro Ser Arg Pro Ala Pro Pro Pro 65 70 75 80 Pro Thr Ser Gly Gln Ala Ser Gly Ala Ser Arg Pro Leu Pro Pro Ile 85 90 95 Ala Gln Ala Leu Lys Glu His Leu Ala Ala Tyr Glu Lys Ser Lys Gly 100 105 110 Pro Glu Ala Leu Gly Phe Lys Pro Ala Arg Gln Ala Pro Pro Pro Pro 115 120 125 Thr Ser Gly Gln Ala Ser Gly Ala Ser Arg Pro Leu Pro Pro Ile Ala 130 135 140 Gln Ala Leu Lys Glu His Leu Ala Ala Tyr Glu Lys Ser Lys Gly Pro 145 150 155 160 Glu Ala Leu Gly Phe Lys Pro Ala Arg Gln Ala Pro Pro Pro Pro Thr 165 170 175 Ser Gly Gln Ala Ser Gly Ala Ser Arg Pro Leu Pro Pro Ile Ala Gln 180 185 190 Ala Leu Lys Glu His Leu Ala Ala Tyr Glu Lys Ser Lys Gly Pro Glu 195 200 205 Ala Leu Gly Phe Lys Pro Ala Arg Gln Ala Pro Pro Pro Pro Thr Gly 210 215 220 Pro Ser Gly Leu Pro Pro Leu Ala Gln Ala Leu Lys Asp His Leu Ala 225 230 235 240 Ala Tyr Glu Gln Ser Lys Lys Gly * 245 <210> 834 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9225..9503) <400> 834 Met Val Asn Asp Ile Ser Ala Asn Lys Ile Leu Val Trp Ala Ala Val 1 5 10 15 Ala Ala Ala Asn His Lys Leu Pro Lys Tyr Ala Glu Ala Ile Leu Asn 20 25 30 Val Phe Pro Gln Ile Ile Pro Asp Lys Lys Asp Ile Ala His Leu Glu 35 40 45 Phe Ile Ile Leu Phe Gly Leu Asn Arg Lys Asn Asp Ala Val Lys Ala 50 55 60 Leu Glu Asp Cys Met Asp Asp Glu Thr Ser Gln Leu Leu Tyr Ser Leu 65 70 75 80 Val His Glu Asn Gly Ser Gly Trp Val Arg Gly Phe * 85 90 <210> 835 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9509..9730) <400> 835 Met Asn Leu Ser Glu Ile Thr Gln Gln Met Gly Glu Val Gly Lys Thr 1 5 10 15 Leu Ser Asp Ser Val Pro Glu Leu Leu Asn Ser Thr Asp Leu Val Asn 20 25 30 Asp Pro Glu Lys Met Leu Glu Leu Gln Phe Ala Val Gln Gln Tyr Ser 35 40 45 Ala Tyr Val Asn Val Glu Ser Gly Met Leu Lys Thr Ile Lys Asp Leu 50 55 60 Val Ser Thr Ile Ser Asn Arg Ser Phe * 65 70 <210> 836 <211> 136 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9766..10173) <400> 836 Met Val Asp Thr Phe Asn Asp Glu Val Phe Asn Tyr Tyr Leu Glu Gln 1 5 10 15 Lys Gly Tyr Thr Ile Gln Lys Glu Phe Leu Cys Gly Ser Ala Phe Phe 20 25 30 Ile Gly Trp Arg Ile Glu Thr Pro Phe Phe Ser Leu Ala Tyr Arg Leu 35 40 45 Asp Glu Gln Glu Leu Ile Leu Cys Ser Phe Glu Ala Arg Asn Gln Thr 50 55 60 Gly Leu Asn Gly Pro Val Leu Ser Leu Thr His Leu Leu Glu Glu Leu 65 70 75 80 Tyr His His Phe Ser Gly Ile Lys Lys Ile Ser Ala Met Lys Ser Lys 85 90 95 Ile Gly Ser Asp Ser Glu Arg Gln Lys Arg Glu Glu Leu Phe Asn Tyr 100 105 110 Phe Ile Arg Lys Gly Ala Val Gln Gln Glu Thr Glu Asp Gly Ile Trp 115 120 125 Phe Val Met Asn Val Asn Ser * 130 135 <210> 837 <211> 313 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10180..11118) <400> 837 Met Asn Thr Ile Asp Asn Thr Gln Val Thr Met Val Asn Ser Ala Ser 1 5 10 15 Glu Ser Thr Thr Gly Ala Ser Ser Ala Val Ala Ala Ser Ala Leu Ser 20 25 30 Ile Asp Ser Ser Leu Leu Thr Asp Gly Lys Val Asp Ile Cys Lys Leu 35 40 45 Met Leu Glu Ile Gln Lys Leu Leu Gly Lys Met Val Thr Leu Leu Gln 50 55 60 Asp Tyr Gln Gln Lys Gln Leu Ala Gln Ser Tyr Gln Ile Gln Gln Ala 65 70 75 80 Val Phe Glu Ser Gln Asn Lys Ala Ile Glu Glu Lys Lys Ala Ala Ala 85 90 95 Thr Ala Ala Leu Val Gly Gly Ile Ile Ser Ser Ala Leu Gly Ile Leu 100 105 110 Gly Ser Phe Ala Ala Met Asn Asn Ala Ala Lys Gly Ala Gly Glu Ile 115 120 125 Ala Glu Lys Ala Ser Ser Ala Ser Ser Lys Ala Ala Gly Ala Ala Ser 130 135 140 Glu Val Ala Asn Lys Ala Leu Val Lys Ala Thr Glu Ser Val Ala Asp 145 150 155 160 Val Ala Glu Glu Ala Ser Ser Ala Met Gln Lys Ala Met Ala Thr Thr 165 170 175 Thr Lys Ala Ala Ser Arg Ala Ser Gly Val Ala Asp Asp Val Ala Lys 180 185 190 Ala Ser Asp Phe Ala Glu Asp Leu Ala Asp Ala Ala Glu Lys Thr Ser 195 200 205 Arg Ile Asn Lys Leu Leu Asn Ser Val Asp Lys Leu Thr Asn Thr Thr 210 215 220 Ala Phe Val Ala Val Thr Ser Leu Ala Glu Gly Thr Lys Thr Leu Pro 225 230 235 240 Thr Thr Ile Ser Glu Ser Val Lys Ser Thr His Glu Val Asn Glu Gln 245 250 255 Arg Ala Lys Ser Leu Glu Asn Phe Gln Gln Gly Asn Leu Glu Leu Tyr 260 265 270 Lys Gln Asp Val Arg Arg Thr Gln Asp Asp Ile Thr Thr Arg Leu Arg 275 280 285 Asp Ile Thr Ser Ala Val Arg Asp Leu Leu Glu Val Gln Asn Arg Met 290 295 300 Gly Gln Ser Gly Arg Leu Ala Gly * 305 310 <210> 838 <211> 375 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11139..12263) <400> 838 Met Leu Asn Val Asn Asn Asp Thr Leu Ser Val Thr Ser Gly Val Asn 1 5 10 15 Thr Ala Ser Gly Thr Ser Gly Ile Thr Gln Ser Glu Thr Gly Leu Ser 20 25 30 Leu Asp Leu Gln Leu Val Lys Ser Met Asn Ser Ser Ala Gly Trp Thr 35 40 45 Glu Ser Ser Pro Leu Pro Thr Pro Pro Ala Gly His Ser Leu Val Thr 50 55 60 Pro Ser Ala Ala Glu Asp Val Leu Ser Lys Leu Phe Gly Gly Ile Ser 65 70 75 80 Gly Glu Val Thr Ser Arg Thr Glu Glu Ala Glu Pro Gln Arg Thr Ser 85 90 95 Tyr Pro Tyr Leu Ser Gln Val Asn Thr Val Asp Pro Gln Gln Met Met 100 105 110 Met Met Val Thr Leu Leu Ser Leu Asp Thr Ser Ala Gln Lys Val Ser 115 120 125 Ser Leu Lys Asn Ser Asn Glu Ile Tyr Met Asp Gly Gln Thr Lys Ala 130 135 140 Leu Glu Asn Lys Thr Gln Glu Tyr Lys Lys Gln Leu Glu Glu Gln Gln 145 150 155 160 Lys Ala Glu Glu Lys Ser Gln Lys Ser Lys Ile Val Gly Gln Val Phe 165 170 175 Gly Trp Leu Gly Val Ala Leu Thr Ala Val Ala Ala Val Phe Asn Pro 180 185 190 Ala Leu Trp Ala Val Val Ala Ile Gly Ala Thr Ala Met Ala Leu Gln 195 200 205 Thr Ala Val Asp Val Met Gly Glu Asn Ala Pro Gln Gly Leu Lys Thr 210 215 220 Ala Ala Gln Val Phe Gly Gly Ile Ser Met Ala Ala Ser Ile Leu Thr 225 230 235 240 Ala Gly Val Gly Gly Val Ser Ser Leu Leu Ser Lys Phe Gly Asn Val 245 250 255 Ala Asn Lys Ile Gly Ser Ser Val Val Lys Val Val Glu Lys Ala Ala 260 265 270 Glu Ala Leu Val Lys Asn Val Phe Ala Lys Ile Ser Thr Val Ala Glu 275 280 285 Gly Val Thr Asn Gly Ile Arg Ser Ala Gly Thr Thr Ala Leu Asn Asn 290 295 300 Glu Ala Ala Gln Leu Gln Met Leu Ser Gln Leu Ala Ala Phe Ala Val 305 310 315 320 Gln Asn Leu Thr Arg Gln Ser Glu Ser Leu Gly Glu Ser Ala Lys Leu 325 330 335 Glu Leu Asp Lys Ala Ala Ser Glu Leu Gln Asn Gln Ala Ser Tyr Leu 340 345 350 Gln Ser Val Ser Gln Leu Met Ser Asp Ser Ala Arg Val Asn Ser Arg 355 360 365 Ile Val Ser Gly Arg Ile * 370 <210> 839 <211> 193 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12276..12854) <400> 839 Met Asp Thr Ser Asn Ala Thr Ser Val Val Asn Val Ser Ala Ser Ser 1 5 10 15 Ser Thr Ser Thr Ile Tyr Asp Leu Gly Asn Met Ser Lys Asp Glu Val 20 25 30 Val Lys Leu Phe Glu Glu Leu Gly Val Phe Gln Ala Ala Ile Leu Met 35 40 45 Phe Ser Tyr Met Tyr Gln Ala Gln Ser Asn Leu Ser Ile Ala Lys Phe 50 55 60 Ala Asp Met Asn Glu Ala Ser Lys Ala Ser Thr Thr Ala Gln Lys Met 65 70 75 80 Ala Asn Leu Val Asp Ala Lys Ile Ala Asp Val Gln Ser Ser Thr Asp 85 90 95 Lys Asn Ala Lys Ala Lys Leu Pro Gln Asp Val Ile Asp Tyr Ile Asn 100 105 110 Asp Pro Arg Asn Asp Ile Ser Val Thr Gly Ile Arg Asp Leu Ser Gly 115 120 125 Asp Leu Ser Ala Gly Asp Leu Gln Thr Val Lys Ala Ala Ile Ser Ala 130 135 140 Lys Ala Asn Asn Leu Thr Thr Val Val Asn Asn Ser Gln Leu Glu Ile 145 150 155 160 Gln Gln Met Ser Asn Thr Leu Asn Leu Leu Thr Ser Ala Arg Ser Asp 165 170 175 Val Gln Ser Leu Gln Tyr Arg Thr Ile Ser Ala Ile Ser Leu Gly Lys 180 185 190 * <210> 840 <211> 352 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12913..13968) <400> 840 Met Ala Asn Gly Ile Glu Phe Asn Gln Asn Pro Ala Ser Val Phe Asn 1 5 10 15 Ser Asn Ser Leu Asp Phe Glu Leu Glu Ser Gln Gln Leu Thr Gln Lys 20 25 30 Asn Ser Ser Asn Ile Ser Ser Pro Leu Ile Asn Leu Gln Asn Glu Leu 35 40 45 Ala Met Ile Thr Ser Ser Ser Leu Ser Glu Thr Ile Glu Gly Leu Ser 50 55 60 Leu Gly Tyr Arg Lys Gly Ser Ala Arg Lys Glu Glu Glu Gly Ser Thr 65 70 75 80 Ile Glu Lys Leu Leu Asn Asp Met Gln Glu Leu Leu Thr Leu Thr Asp 85 90 95 Ser Asp Lys Ile Lys Glu Leu Ser Leu Lys Asn Ser Gly Leu Leu Glu 100 105 110 Gln His Asp Pro Thr Leu Ala Met Phe Gly Asn Met Pro Lys Gly Glu 115 120 125 Ile Val Ala Leu Ile Ser Ser Leu Leu Gln Ser Lys Phe Val Lys Ile 130 135 140 Glu Leu Lys Lys Lys Tyr Ala Arg Leu Leu Leu Asp Leu Leu Gly Glu 145 150 155 160 Asp Asp Trp Glu Leu Ala Leu Leu Ser Trp Leu Gly Val Gly Glu Leu 165 170 175 Asn Gln Glu Gly Ile Gln Lys Ile Lys Lys Leu Tyr Glu Lys Ala Lys 180 185 190 Asp Glu Asp Ser Glu Asn Gly Ala Ser Leu Leu Asp Trp Phe Met Glu 195 200 205 Ile Lys Asp Leu Pro Glu Arg Glu Lys His Leu Lys Val Ile Ile Arg 210 215 220 Ala Leu Ser Phe Asp Leu Ser Tyr Met Ser Ser Phe Glu Asp Lys Val 225 230 235 240 Lys Thr Ser Ser Ile Ile Ser Asp Leu Cys Arg Val Ile Ile Phe Leu 245 250 255 Ser Leu Asp Asn Tyr Ala Asp Ile Ile Ser Ile Ser Ile Lys Lys Asp 260 265 270 Lys Asp Ile Ile Leu Asn Glu Val Leu Ser Ile Ile Glu His Val Trp 275 280 285 Leu Thr Glu Asp Trp Leu Leu Glu Ser Pro Ser Arg Val Ser Ile Val 290 295 300 Glu Asp Lys His Ile Tyr Tyr Phe His Leu Leu Lys Asp Phe Phe Thr 305 310 315 320 Ser Leu Pro Asp Ala Cys Phe Ile Asp Ser Glu Gln Arg Glu Asn Ala 325 330 335 Leu Leu Met Ile Gly Lys Val Ile Asp Tyr Lys Glu Glu Ile Ile * 340 345 350 <210> 841 <211> 407 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14111..15331) <400> 841 Met Leu Ser Ser Tyr Lys Ile Lys Leu Leu Asn Gly Ala Met Arg Asn 1 5 10 15 Arg Glu Leu Gln Leu Pro Met Gly Asn Leu Thr Leu Gly Thr Glu Asp 20 25 30 Asn Asp Ile Val Tyr Phe Pro Leu Glu Gln Gly Leu Asn Gln Phe Leu 35 40 45 Leu Asp Ile Arg Glu Glu Gly Val Phe Leu Leu Ser Pro Val Glu Phe 50 55 60 Trp Ile Asp Gly Gln Pro Thr Pro Tyr Glu Ala Asp Lys Pro Leu Pro 65 70 75 80 Val Gly Lys Val Ile Asp Ile Ala Gly Cys Cys Phe Ile Ile Gly Asp 85 90 95 Ile Asp His Ser Leu Pro Leu Ser Asp Val Pro Glu Arg Phe Ser Ala 100 105 110 Lys Ser Arg Arg Lys Lys Arg Leu Ile Leu Ala Ser Val Ile Gly Ala 115 120 125 Thr Phe Ala Leu Ser Gly Ala Ile Gly Ser Tyr Val Leu Leu Ser Pro 130 135 140 Lys Ala Glu Pro Pro Thr Phe Thr Arg Ala Asp Val Tyr Gln Gln Leu 145 150 155 160 Lys Glu Asn Lys Leu His Ala Ile Thr Leu Val Trp His Gly Lys Asn 165 170 175 Ile Ala Leu Tyr Gly Arg Cys Glu Ser Thr Thr Asp Leu Thr Pro Phe 180 185 190 Phe Asn Tyr Leu Lys Glu Lys Asn Ile Phe Tyr Tyr Asn Asn Ile Ile 195 200 205 Cys Asn Asn Gln Ile Ile Ser Ala Ile Asn Asp Val Leu Thr Glu Tyr 210 215 220 Gly Tyr Lys Asp Ile Ile Ile Thr Lys Gly Asn Lys Pro Gly Phe Phe 225 230 235 240 Leu Leu Ser Gly Tyr Ile Pro Pro Ser Pro Lys Trp Ser Glu Val Glu 245 250 255 Asn Leu Leu Leu Asn Thr Pro Gly Val Ala Gly Trp Glu Ile His Asn 260 265 270 Asn Ser Asn Asn Lys Ile Asn Glu Leu Ala Ser Glu Phe Lys Lys Asn 275 280 285 Lys Leu Ile Asn Tyr Val Asn Ile Phe Lys Lys Asn Asp Val Ile Ile 290 295 300 Val Ala Gly Glu Val Ser Gln Gln Asn Glu Ser Lys Ile Leu Ala Ile 305 310 315 320 Ile Asn Ala Met Asn Lys Asn Ser Asn Ala Lys Ile Leu Phe Gln Asn 325 330 335 Ile Gln Pro Tyr Ile Ser Ala Asp Ile Phe Pro Gly Lys Ile Leu Arg 340 345 350 Ile Ser Gly Thr Met Lys Asn Pro Thr Ile Ala Leu Asp Asn Gly Thr 355 360 365 Ser Leu Gly Ile Gly Ser Ile Leu Lys Gly Gly Tyr Val Ile Asp Ala 370 375 380 Ile Asp Pro Lys Asp Gly Ile Asn Ile Ser Arg Pro Asp Glu Tyr Ile 385 390 395 400 His Ile Pro Leu Ser Tyr * 405 <210> 842 <211> 935 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15595..18399) <400> 842 Met Ile Thr His Gly Cys Tyr Thr Arg Thr Arg His Lys His Lys Leu 1 5 10 15 Lys Lys Thr Leu Ile Met Leu Ser Ala Gly Leu Gly Leu Phe Phe Tyr 20 25 30 Val Asn Gln Asn Ser Phe Ala Asn Gly Glu Asn Tyr Phe Lys Leu Gly 35 40 45 Ser Asp Ser Lys Leu Leu Thr His Asp Ser Tyr Gln Asn Arg Leu Phe 50 55 60 Tyr Thr Leu Lys Thr Gly Glu Thr Val Ala Asp Leu Ser Lys Ser Gln 65 70 75 80 Asp Ile Asn Leu Ser Thr Ile Trp Ser Leu Asn Lys His Leu Tyr Ser 85 90 95 Ser Glu Ser Glu Met Met Lys Ala Ala Pro Gly Gln Gln Ile Ile Leu 100 105 110 Pro Leu Lys Lys Leu Pro Phe Glu Tyr Ser Ala Leu Pro Leu Leu Gly 115 120 125 Ser Ala Pro Leu Val Ala Ala Gly Gly Val Ala Gly His Thr Asn Lys 130 135 140 Leu Thr Lys Met Ser Pro Asp Val Thr Lys Ser Asn Met Thr Asp Asp 145 150 155 160 Lys Ala Leu Asn Tyr Ala Ala Gln Gln Ala Ala Ser Leu Gly Ser Gln 165 170 175 Leu Gln Ser Arg Ser Leu Asn Gly Asp Tyr Ala Lys Asp Thr Ala Leu 180 185 190 Gly Ile Ala Gly Asn Gln Ala Ser Ser Gln Leu Gln Ala Trp Leu Gln 195 200 205 His Tyr Gly Thr Ala Glu Val Asn Leu Gln Ser Gly Asn Asn Phe Asp 210 215 220 Gly Ser Ser Leu Asp Phe Leu Leu Pro Phe Tyr Asp Ser Glu Lys Met 225 230 235 240 Leu Ala Phe Gly Gln Val Gly Ala Arg Tyr Ile Asp Ser Arg Phe Thr 245 250 255 Ala Asn Leu Gly Ala Gly Gln Arg Phe Phe Leu Pro Ala Asn Met Leu 260 265 270 Gly Tyr Asn Val Phe Ile Asp Gln Asp Phe Ser Gly Asp Asn Thr Arg 275 280 285 Leu Gly Ile Gly Gly Glu Tyr Trp Arg Asp Tyr Phe Lys Ser Ser Val 290 295 300 Asn Gly Tyr Phe Arg Met Ser Gly Trp His Glu Ser Tyr Asn Lys Lys 305 310 315 320 Asp Tyr Asp Glu Arg Pro Ala Asn Gly Phe Asp Ile Arg Phe Asn Gly 325 330 335 Tyr Leu Pro Ser Tyr Pro Ala Leu Gly Ala Lys Leu Ile Tyr Glu Gln 340 345 350 Tyr Tyr Gly Asp Asn Val Ala Leu Phe Asn Ser Asp Lys Leu Gln Ser 355 360 365 Asn Pro Gly Ala Ala Thr Val Gly Val Asn Tyr Thr Pro Ile Pro Leu 370 375 380 Val Thr Met Gly Ile Asp Tyr Arg His Gly Thr Gly Asn Glu Asn Asp 385 390 395 400 Leu Leu Tyr Ser Met Gln Phe Arg Tyr Gln Phe Asp Lys Ser Trp Ser 405 410 415 Gln Gln Ile Glu Pro Gln Tyr Val Asn Glu Leu Arg Thr Leu Ser Gly 420 425 430 Ser Arg Tyr Asp Leu Val Gln Arg Asn Asn Asn Ile Ile Leu Glu Tyr 435 440 445 Lys Lys Gln Asp Ile Leu Ser Leu Asn Ile Pro His Asp Ile Asn Gly 450 455 460 Thr Glu His Ser Thr Gln Lys Ile Gln Leu Ile Val Lys Ser Lys Tyr 465 470 475 480 Gly Leu Asp Arg Ile Val Trp Asp Asp Ser Ala Leu Arg Ser Gln Gly 485 490 495 Gly Gln Ile Gln His Ser Gly Ser Gln Ser Ala Gln Asp Tyr Gln Ala 500 505 510 Ile Leu Pro Ala Tyr Val Gln Gly Gly Ser Asn Ile Tyr Lys Val Thr 515 520 525 Ala Arg Ala Tyr Asp Arg Asn Gly Asn Ser Ser Asn Asn Val Gln Leu 530 535 540 Thr Ile Thr Val Leu Ser Asn Gly Gln Val Val Asp Gln Val Gly Val 545 550 555 560 Thr Asp Phe Thr Ala Asp Lys Thr Ser Ala Lys Ala Asp Asn Ala Asp 565 570 575 Thr Ile Thr Tyr Thr Ala Thr Val Lys Lys Asn Gly Val Ala Gln Ala 580 585 590 Asn Val Pro Val Ser Phe Asn Ile Val Ser Gly Thr Ala Thr Leu Gly 595 600 605 Ala Asn Ser Ala Lys Thr Asp Ala Asn Gly Lys Ala Thr Val Thr Leu 610 615 620 Lys Ser Ser Thr Pro Gly Gln Val Val Val Ser Ala Lys Thr Ala Glu 625 630 635 640 Met Thr Ser Ala Leu Asn Ala Ser Ala Val Ile Phe Phe Asp Gln Thr 645 650 655 Lys Ala Ser Ile Thr Glu Ile Lys Ala Asp Lys Thr Thr Ala Val Ala 660 665 670 Asn Gly Lys Asp Ala Ile Lys Tyr Thr Val Lys Val Met Lys Asn Gly 675 680 685 Gln Pro Val Asn Asn Gln Ser Val Thr Phe Ser Thr Asn Phe Gly Met 690 695 700 Phe Asn Gly Lys Ser Gln Thr Gln Ala Thr Thr Gly Asn Asp Gly Arg 705 710 715 720 Ala Thr Ile Thr Leu Thr Ser Ser Ser Ala Gly Lys Ala Thr Val Ser 725 730 735 Ala Thr Val Ser Asp Gly Ala Glu Val Lys Ala Thr Glu Val Thr Phe 740 745 750 Phe Asp Glu Leu Lys Ile Asp Asn Lys Val Asp Ile Ile Gly Asn Asn 755 760 765 Val Arg Gly Glu Leu Pro Asn Ile Trp Leu Gln Tyr Gly Gln Phe Lys 770 775 780 Leu Lys Ala Ser Gly Gly Asp Gly Thr Tyr Ser Trp Tyr Ser Glu Asn 785 790 795 800 Thr Ser Ile Ala Thr Val Asp Ala Ser Gly Lys Val Thr Leu Asn Gly 805 810 815 Lys Gly Ser Val Val Ile Lys Ala Thr Ser Gly Asp Lys Gln Thr Val 820 825 830 Ser Tyr Thr Ile Lys Ala Pro Ser Tyr Met Ile Lys Val Asp Lys Gln 835 840 845 Ala Tyr Tyr Ala Asp Ala Met Ser Ile Cys Lys Asn Leu Leu Pro Ser 850 855 860 Thr Gln Thr Val Leu Ser Asp Ile Tyr Asp Ser Trp Gly Ala Ala Asn 865 870 875 880 Lys Tyr Ser His Tyr Ser Ser Met Asn Ser Ile Thr Ala Trp Ile Lys 885 890 895 Gln Thr Ser Ser Glu Gln Arg Ser Gly Val Ser Ser Thr Tyr Asn Leu 900 905 910 Ile Thr Gln Asn Pro Leu Pro Gly Val Asn Val Asn Thr Pro Asn Val 915 920 925 Tyr Ala Val Cys Val Glu * 930 <210> 843 <211> 157 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18459..18929) <400> 843 Met Ser Ser Arg Ser Glu Leu Leu Leu Glu Lys Phe Ala Glu Lys Ile 1 5 10 15 Gly Ile Gly Ser Ile Ser Phe Asn Glu Asn Arg Leu Cys Ser Phe Ala 20 25 30 Ile Asp Glu Ile Tyr Tyr Ile Ser Leu Ser Asp Ala Asn Asp Glu Tyr 35 40 45 Met Met Ile Tyr Gly Val Cys Gly Lys Phe Pro Thr Asp Asn Ser Asn 50 55 60 Phe Ala Leu Glu Ile Leu Asn Ala Asn Leu Trp Phe Ala Glu Asn Gly 65 70 75 80 Gly Pro Tyr Leu Cys Tyr Glu Ala Gly Ala Gln Ser Leu Leu Leu Ala 85 90 95 Leu Arg Phe Pro Leu Asp Asp Ala Thr Pro Glu Lys Leu Glu Asn Glu 100 105 110 Ile Glu Val Val Val Lys Ser Met Glu Asn Leu Tyr Leu Val Leu His 115 120 125 Asn Gln Gly Ile Thr Leu Glu Asn Glu His Met Lys Ile Glu Glu Ile 130 135 140 Ser Ser Ser Asp Asn Lys His Tyr Tyr Ala Gly Arg * 145 150 155 <210> 844 <211> 559 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19067..20743) <400> 844 Met Pro Ile Gly Asn Leu Gly His Asn Pro Asn Val Asn Asn Ser Ile 1 5 10 15 Pro Pro Ala Pro Pro Leu Pro Ser Gln Thr Asp Gly Ala Gly Gly Arg 20 25 30 Gly Gln Leu Ile Asn Ser Thr Gly Pro Leu Gly Ser Arg Ala Leu Phe 35 40 45 Thr Pro Val Arg Asn Ser Met Ala Asp Ser Gly Asp Asn Arg Ala Ser 50 55 60 Asp Val Pro Gly Leu Pro Val Asn Pro Met Arg Leu Ala Ala Ser Glu 65 70 75 80 Ile Thr Leu Asn Asp Gly Phe Glu Val Leu His Asp His Gly Pro Leu 85 90 95 Asp Thr Leu Asn Arg Gln Ile Gly Ser Ser Val Phe Arg Val Glu Thr 100 105 110 Gln Glu Asp Gly Lys His Ile Ala Val Gly Gln Arg Asn Gly Val Glu 115 120 125 Thr Ser Val Val Leu Ser Asp Gln Glu Tyr Ala Arg Leu Gln Ser Ile 130 135 140 Asp Pro Glu Gly Lys Asp Lys Phe Val Phe Thr Gly Gly Arg Gly Gly 145 150 155 160 Ala Gly His Ala Met Val Thr Val Ala Ser Asp Ile Thr Glu Ala Arg 165 170 175 Gln Arg Ile Leu Glu Leu Leu Glu Pro Lys Gly Thr Gly Glu Ser Lys 180 185 190 Gly Ala Gly Glu Ser Lys Gly Val Gly Glu Leu Arg Glu Ser Asn Ser 195 200 205 Gly Ala Glu Asn Thr Thr Glu Thr Gln Thr Ser Thr Ser Thr Ser Ser 210 215 220 Leu Arg Ser Asp Pro Lys Leu Trp Leu Ala Leu Gly Thr Val Ala Thr 225 230 235 240 Gly Leu Ile Gly Leu Ala Ala Thr Gly Ile Val Gln Ala Leu Ala Leu 245 250 255 Thr Pro Glu Pro Asp Ser Pro Thr Thr Thr Asp Pro Asp Ala Ala Ala 260 265 270 Ser Ala Thr Glu Thr Ala Thr Arg Asp Gln Leu Thr Lys Glu Ala Phe 275 280 285 Gln Asn Pro Asp Asn Gln Lys Val Asn Ile Asp Glu Leu Gly Asn Ala 290 295 300 Ile Pro Ser Gly Val Leu Lys Asp Asp Val Val Ala Asn Ile Glu Glu 305 310 315 320 Gln Ala Lys Ala Ala Gly Glu Glu Ala Lys Gln Gln Ala Ile Glu Asn 325 330 335 Asn Ala Gln Ala Gln Lys Lys Tyr Asp Glu Gln Gln Ala Lys Arg Gln 340 345 350 Glu Glu Leu Lys Val Ser Ser Gly Ala Gly Tyr Gly Leu Ser Gly Ala 355 360 365 Leu Ile Leu Gly Gly Gly Ile Gly Val Ala Val Thr Ala Ala Leu His 370 375 380 Arg Lys Asn Gln Pro Val Glu Gln Thr Thr Thr Thr Thr Thr Thr Thr 385 390 395 400 Thr Thr Thr Ser Ala Arg Thr Val Glu Asn Lys Pro Ala Asn Asn Thr 405 410 415 Pro Ala Gln Gly Asn Val Asp Thr Pro Gly Ser Glu Asp Thr Met Glu 420 425 430 Ser Arg Arg Ser Ser Met Ala Ser Thr Ser Ser Thr Phe Phe Asp Thr 435 440 445 Ser Ser Ile Gly Thr Val Gln Asn Pro Tyr Ala Asp Val Lys Thr Ser 450 455 460 Leu His Asp Ser Gln Val Pro Thr Ser Asn Ser Asn Thr Ser Val Gln 465 470 475 480 Asn Met Gly Asn Thr Asp Ser Val Val Tyr Ser Thr Ile Gln His Pro 485 490 495 Pro Arg Asp Thr Thr Asp Asn Gly Ala Arg Leu Leu Gly Asn Pro Ser 500 505 510 Ala Gly Ile Gln Ser Thr Tyr Ala Arg Leu Ala Leu Ser Gly Gly Leu 515 520 525 Arg His Asp Met Gly Gly Leu Thr Gly Gly Ser Asn Ser Ala Val Asn 530 535 540 Thr Ser Asn Asn Pro Pro Ala Pro Gly Ser His Arg Phe Val * 545 550 555 <210> 845 <211> 204 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21167..21778) <400> 845 Met Phe Ser Pro Met Thr Met Ala Gly Arg Ser Leu Val Gln Ala Thr 1 5 10 15 Ala Gln Thr Leu Lys Pro Ala Val Thr Arg Ala Ala Met Gln Ala Gly 20 25 30 Thr Gly Ala Thr Gly Met Arg Phe Met Pro Val Gln Ser Asn Phe Val 35 40 45 Ile Asn His Gly Lys Leu Thr Asn Gln Leu Leu Gln Ala Val Ala Lys 50 55 60 Gln Thr Arg Asn Gly Asp Thr Gln Gln Trp Phe Gln Gln Glu Gln Thr 65 70 75 80 Thr Tyr Ile Ser Arg Thr Val Asn Arg Thr Leu Asp Asp Tyr Cys Arg 85 90 95 Ser Asn Asn Ser Val Ile Ser Lys Glu Thr Lys Gly His Ile Phe Arg 100 105 110 Ala Val Glu Asn Ala Leu Gln Gln Pro Leu Asp Met Asn Gly Ala Gln 115 120 125 Ser Ser Ile Gly His Phe Leu Gln Ser Asn Lys Tyr Phe Asn Gln Lys 130 135 140 Val Asp Glu Gln Cys Gly Lys Arg Val Asp Pro Ile Thr Arg Phe Asn 145 150 155 160 Thr Gln Thr Lys Met Ile Glu Gln Val Ser Gln Glu Ile Phe Glu Arg 165 170 175 Asn Phe Ser Gly Phe Lys Val Ser Glu Ile Lys Ala Ile Thr Gln Asn 180 185 190 Ala Ile Leu Glu His Val Gln Asp Thr Arg Leu * 195 200 <210> 846 <211> 128 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22044..22427) <400> 846 Met Asn Glu Lys Phe Arg Thr Asp Leu Ala His Thr Phe Gly Ile Ala 1 5 10 15 Leu Glu Glu Gln Thr Asp Val Leu Ser Phe His Asp Asn Asp Gly His 20 25 30 Glu Trp Ile Leu Glu Cys Ala Ser Gln Ser Glu Ile Leu Phe Phe Tyr 35 40 45 Cys Tyr Leu Leu Asn Ser Glu Ser Ile Gln Ile Asn Ser Ile Leu Glu 50 55 60 Met Asn Ser Asn Arg Glu Leu Leu Gly Met Phe Phe Leu Ser Leu Lys 65 70 75 80 Asp Asp Asn Ile Leu Leu Asn Ile Ala Phe Pro Ala Asp Lys Ile Asp 85 90 95 Ile Thr Glu Phe Ala Asn Leu Met Glu Asn Gly Tyr Leu Leu Lys Asn 100 105 110 Glu Ile Ile Arg Ser Leu Ser Ser Arg Pro Thr Asp Phe Leu Pro * 115 120 125 <210> 847 <211> 169 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22625..23131) <400> 847 Met Ser Leu Ser Gly Ala Val Phe Lys Thr Phe Leu Thr Ser Glu His 1 5 10 15 Ala Ser Trp Asn Arg Phe Asn Arg Arg Leu His Ile Pro Asn Glu Asp 20 25 30 Ile Val Asp Glu Ile Gln Leu Lys Ala Arg Met Gln Gln Arg His His 35 40 45 Arg Val Tyr Pro Glu Ile Gly Asp Ser Thr Ile Val Ser Phe Arg Gly 50 55 60 Lys Asp Tyr Ala Val His Phe Ile Lys Asp Gly Pro Lys Asp Asp Tyr 65 70 75 80 Val Tyr Lys Val Gln Arg Ile Thr Pro Glu Asn Gly Cys Phe Ser Thr 85 90 95 Leu Phe Ser Val Phe Ser Gly Gly Val Thr Lys Ala Leu Glu Arg Lys 100 105 110 Leu Asn Glu Arg His Ile Thr Pro Leu Ser Ser Thr Trp Phe Pro Arg 115 120 125 Thr Pro Leu Glu Gly Ile Leu Ala Glu Arg Gly Leu Ser Ser Leu Leu 130 135 140 Arg Arg Val Gln Ser Thr Glu Arg Leu Asp Asn Arg Ala Ile Ala Thr 145 150 155 160 Arg Ala Ser Ser Tyr Ser Val Leu * 165 <210> 848 <211> 306 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23162..24079) <400> 848 Met Lys Pro Leu Ser Ser Gln Leu Asn Met Lys Ile Asn Asp Phe Tyr 1 5 10 15 Leu Pro Leu Leu Pro Val Ile Gly Thr Gly Arg Leu Tyr Ile Thr Ser 20 25 30 Lys Gly His Ala Cys His Ala Tyr Phe Arg Glu Val Ser Gly His Gly 35 40 45 Ile Arg Phe Thr Leu Thr Tyr Ser Gly Tyr Glu Gly Arg Phe Trp Ile 50 55 60 Ser Glu Glu Gln Phe Ile Gln Trp Cys Gln Glu Leu Phe Pro Tyr Ser 65 70 75 80 Glu Ser Arg Leu Ile Pro Glu Asp Thr Ile Lys Leu Met Ile Leu Trp 85 90 95 Val Met Gln Thr Ala Leu Pro Glu Gly Asp Val Ser Val Asp Asp Val 100 105 110 Gln Phe Thr Met Leu Asn Lys Asp Ile Tyr Pro Val Ile Glu Asn Asn 115 120 125 Asn Gly Glu Asn Arg Leu Asn Val Ile Ile Leu Glu Thr Thr Val Gln 130 135 140 Ser Leu Gln Tyr Leu Ile Asn Asp Asn Trp Gln Leu Val Pro His Ser 145 150 155 160 Asn Ala Leu Phe Phe Asp Gly Tyr Ile Val Pro Gly Trp Thr Asp Tyr 165 170 175 Pro Val Thr Glu Leu Arg Val Gly Asp Ser Leu Arg Leu Tyr His Val 180 185 190 Asp Asp Ser Gln Glu Arg Arg Cys Trp Ile Val Ile Asn Thr Pro Leu 195 200 205 Ala Thr Val Asn Leu Ser Asp Asn Asn Leu Ser Val Thr Asp Val Leu 210 215 220 Ala Ala Asp Leu Leu Ser Ala Leu Ser Asn Glu Thr Val Met Asn Arg 225 230 235 240 Ile Tyr Cys Ala Ile Gly Thr Val His Ile Asp Ile His Met Leu Arg 245 250 255 Asn Val Lys Lys Asp Asp Ile Ile Asn Ser Asp Gly Tyr His Leu Phe 260 265 270 Gly Gly Cys Gln Leu Ile Arg Asn Asn Thr Thr Ile Ala Tyr Gly Ser 275 280 285 Ile Val Lys Ile Asn Glu Asp Phe Tyr Phe Thr Val Ser Ile Val Cys 290 295 300 Asp * 305 <210> 849 <211> 139 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24042..24458) <400> 849 Leu Thr Arg Val Ser Leu Lys Arg Asn Leu Ile Glu Pro Val Ser Phe 1 5 10 15 Arg Pro Ser Asp Asp Trp Pro Gln Gly Glu Glu Ser Phe Asn Asp Ile 20 25 30 Phe Tyr His Ile Lys Lys Arg Ser Pro Asp Thr Leu Phe Ile Arg Met 35 40 45 Ala Ser Leu Trp Lys Arg Leu Phe Tyr Ser Ser Gly Arg Arg Arg Arg 50 55 60 Tyr Phe Glu Glu Gly Glu His Ser Phe Ser Ile Leu Cys Gly Arg Leu 65 70 75 80 Arg Gly Ile Val Leu Thr Ile Lys Cys Ser Asn Gly Ile Ile Tyr Leu 85 90 95 Ser Ile Lys Val Ser Pro Asn Asn Arg Asn His Val Phe Leu Tyr His 100 105 110 Lys Lys Asp Tyr Val Phe Asp Lys Leu Lys Glu Ile Phe Pro Asp Glu 115 120 125 Ala Ile Glu Phe Thr Ile Glu Tyr Glu Asn * 130 135 <210> 850 <211> 126 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24451..24828) <400> 850 Met Leu Asp Arg Ile Leu Ser Ile Arg Lys Ser Arg Ala Asn Arg Leu 1 5 10 15 Arg Glu Ser Met Ala Lys Ile Asn Ser Gln Ile Lys Glu Val Asp Gly 20 25 30 Lys Leu Asp Asp Cys Glu Gln Ser Ile Lys Glu Ser Ile Ala Ser Lys 35 40 45 Gln Ala Tyr Cys Ala Ser Leu Val Asn Leu Asp Lys Val Ser Leu Tyr 50 55 60 Lys Tyr Gln Ile Lys Asn Asn Ala Phe Asp Glu Gln Lys Gln Arg Leu 65 70 75 80 Tyr Glu Lys Lys Ser Ser Leu Ser Lys Glu Lys Arg Ser Leu Leu Asp 85 90 95 Ser Gln Lys Arg Thr Lys Glu Asn Leu Gln His Val Asn Lys Ser Val 100 105 110 Glu Lys Leu Ser Phe Ala Ile Lys Glu His Tyr Phe Asp * 115 120 125 <210> 851 <211> 447 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24831..26171) <400> 851 Met Ile Ser Glu His Asp Ser Val Leu Glu Lys Tyr Pro Arg Ile Gln 1 5 10 15 Lys Val Leu Asn Ser Thr Val Pro Ala Leu Ser Leu Asn Ser Ser Thr 20 25 30 Arg Tyr Glu Gly Lys Ile Ile Asn Ile Gly Gly Thr Ile Ile Lys Ala 35 40 45 Arg Leu Pro Lys Ala Arg Ile Gly Ala Phe Tyr Lys Ile Glu Pro Ser 50 55 60 Gln Arg Leu Ala Glu Val Ile Ala Ile Asp Glu Asp Glu Val Phe Leu 65 70 75 80 Leu Pro Phe Glu His Val Ser Gly Met Tyr Cys Gly Gln Trp Leu Ser 85 90 95 Tyr Gln Gly Asp Glu Phe Lys Ile Arg Val Gly Asp Ala Leu Leu Gly 100 105 110 Arg Leu Val Asp Gly Ile Gly Arg Pro Met Glu Ser Asn Ile Ala Ala 115 120 125 Pro Tyr Leu Pro Phe Glu Arg Ser Leu Tyr Ala Glu Pro Pro Asp Pro 130 135 140 Leu Leu Arg Gln Val Ile Asp Gln Pro Phe Ile Leu Gly Val Arg Ala 145 150 155 160 Ile Asp Gly Leu Leu Thr Cys Gly Ile Gly Gln Arg Ile Gly Ile Phe 165 170 175 Ala Gly Ser Gly Val Gly Lys Ser Thr Leu Leu Gly Met Ile Cys Asn 180 185 190 Gly Ala Ser Ala Asp Ile Ile Val Leu Ala Leu Ile Gly Glu Arg Gly 195 200 205 Arg Glu Val Asn Glu Phe Leu Ala Leu Leu Pro Gln Ser Thr Leu Ser 210 215 220 Lys Cys Val Leu Val Val Thr Thr Ser Asp Arg Pro Ala Leu Glu Arg 225 230 235 240 Met Lys Ala Ala Phe Thr Ala Thr Thr Ile Ala Glu Tyr Phe Arg Asp 245 250 255 Gln Gly Lys Asn Val Leu Leu Met Met Asp Ser Val Thr Arg Tyr Ala 260 265 270 Arg Ala Ala Arg Asp Val Gly Leu Ala Ser Gly Glu Pro Asp Val Arg 275 280 285 Gly Gly Phe Pro Pro Ser Val Phe Ser Ser Leu Pro Lys Leu Leu Glu 290 295 300 Arg Ala Gly Pro Ala Pro Lys Gly Ser Ile Thr Ala Ile Tyr Thr Val 305 310 315 320 Leu Leu Glu Ser Asp Asn Val Asn Asp Pro Ile Gly Asp Glu Val Arg 325 330 335 Ser Ile Leu Asp Gly His Ile Val Leu Thr Arg Glu Leu Ala Glu Glu 340 345 350 Asn His Phe Pro Ala Ile Asp Ile Gly Leu Ser Ala Ser Arg Val Met 355 360 365 His Asn Val Val Thr Ser Glu His Leu Arg Ala Ala Ala Glu Cys Lys 370 375 380 Lys Leu Ile Ala Thr Tyr Lys Asn Val Glu Leu Leu Ile Arg Ile Gly 385 390 395 400 Glu Tyr Thr Met Gly Gln Asp Pro Glu Ala Asp Lys Ala Ile Lys Asn 405 410 415 Arg Lys Leu Ile Gln Asn Phe Ile Gln Gln Ser Thr Lys Asp Ile Ser 420 425 430 Ser Tyr Glu Lys Thr Ile Glu Ser Leu Phe Lys Val Val Ala * 435 440 445 <210> 852 <211> 676 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26155..28182) <400> 852 Met Asn Lys Leu Leu Asn Ile Phe Lys Lys Ala Glu Ser Tyr His Asp 1 5 10 15 Leu Ile Leu Ala Leu Phe Phe Phe Met Ala Val Met Met Met Ile Ile 20 25 30 Pro Leu Pro Thr Val Val Val Asp Ile Ile Ile Ala Ile Asn Ile Ser 35 40 45 Thr Ala Leu Leu Leu Leu Met Leu Ser Ile Tyr Ile Lys Asn Pro Leu 50 55 60 Glu Leu Thr Ser Phe Pro Thr Ile Leu Leu Ile Thr Thr Leu Met Arg 65 70 75 80 Leu Ser Leu Ser Val Ser Thr Thr Arg Leu Ile Leu Leu His His Asp 85 90 95 Ala Gly Asp Ile Ile Tyr Ser Phe Gly Asn Phe Val Val Gly Gly Asn 100 105 110 Ile Val Val Gly Leu Val Ile Phe Thr Ile Ile Thr Ile Val Gln Phe 115 120 125 Met Val Ile Thr Lys Gly Ala Glu Arg Val Ala Glu Val Ser Ala Arg 130 135 140 Phe Ser Leu Asp Gly Met Pro Gly Lys Gln Met Ser Ile Asp Gly Asp 145 150 155 160 Met Arg Ala Gly Val Ile Asp Pro Leu Glu Ala Lys Val Leu Arg Ser 165 170 175 Arg Val Gln Lys Glu Ser Gln Phe Tyr Gly Ser Met Asp Gly Ala Met 180 185 190 Lys Phe Val Lys Gly Asp Ala Ile Ala Gly Ile Ile Ile Val Leu Val 195 200 205 Asn Leu Phe Gly Gly Val Leu Ile Gly Met Trp Gln Phe Asp Met Pro 210 215 220 Phe Ser Ala Ala Leu Ser Leu Phe Ser Val Leu Ser Val Gly Asp Ala 225 230 235 240 Leu Val Ala Gln Ile Pro Ala Leu Ile Ile Ser Val Thr Ala Gly Val 245 250 255 Val Val Thr Arg Val Pro Gly Glu Ser Glu Lys Glu Glu Asn Leu Ala 260 265 270 Gly Asp Ile Val Gln Gln Val Ser Val Asn Ser Arg Pro Phe Leu Ile 275 280 285 Ser Ala Ala Leu Met Leu Val Met Ala Ile Ile Pro Gly Phe Pro Ala 290 295 300 Leu Val Phe Leu Phe Leu Ala Val Cys Leu Leu Gly Ile Ala Trp Lys 305 310 315 320 Leu Gln Lys Lys Arg Thr Phe Gly Thr Gly Asn Asn Lys Asp Ala Met 325 330 335 Gly Ala Asp Leu Ser Asn Ser Gln Asn Ile Ser Pro Gly Ala Glu Pro 340 345 350 Leu Ile Leu Asn Leu Ser Ser Asn Ile Tyr Ser Ser Asp Ile Thr Gln 355 360 365 Gln Ile Glu Val Met Arg Trp Asn Phe Phe Glu Glu Ser Gly Ile Pro 370 375 380 Leu Pro Lys Ile Ile Val Asn Pro Val Lys Asn Asn Asp Ser Ala Ile 385 390 395 400 Glu Phe Leu Leu Tyr Gln Glu Ser Ile Tyr Lys Asp Thr Leu Ile Asp 405 410 415 Asp Thr Val Tyr Phe Glu Ala Gly His Ala Glu Ile Ser Phe Glu Phe 420 425 430 Val Gln Glu Lys Leu Ser Thr Asn Ser Ile Val Tyr Lys Thr Asn Lys 435 440 445 Thr Asn Gln Gln Leu Ala His Leu Thr Gly Met Asp Val Tyr Ala Thr 450 455 460 Thr Asn Asp Lys Ile Thr Phe Leu Leu Lys Lys Leu Val Leu Ser Asn 465 470 475 480 Ala Lys Glu Phe Ile Gly Val Gln Glu Thr Arg Tyr Leu Met Asp Ile 485 490 495 Met Glu Arg Lys Tyr Asn Glu Leu Val Lys Glu Leu Gln Arg Gln Leu 500 505 510 Gly Leu Ser Lys Ile Val Asp Ile Leu Gln Arg Leu Val Glu Glu Asn 515 520 525 Val Ser Ile Arg Asp Leu Arg Thr Ile Phe Glu Thr Leu Ile Phe Trp 530 535 540 Ser Thr Lys Glu Lys Asp Val Val Ile Leu Cys Glu Tyr Val Arg Ile 545 550 555 560 Ala Leu Arg Arg His Ile Leu Gly Arg Tyr Ser Val Ser Gly Thr Leu 565 570 575 Leu Asn Val Trp Leu Ile Gly Ser Asp Ile Glu Asn Glu Leu Arg Glu 580 585 590 Ser Ile Arg Gln Thr Ser Ser Gly Ser Tyr Leu Asn Ile Ser Pro Glu 595 600 605 Arg Thr Glu Gln Ile Ile Gly Phe Leu Lys Asn Ile Met Asn Pro Thr 610 615 620 Gly Asn Gly Val Ile Leu Thr Ala Leu Asp Ile Arg Arg Tyr Val Lys 625 630 635 640 Lys Met Ile Glu Gly Ser Phe Pro Ser Val Pro Val Leu Ser Phe Gln 645 650 655 Glu Val Gly Asn Asn Ile Glu Leu Lys Val Leu Gly Thr Val Asn Asp 660 665 670 Phe Arg Ala * 675 <210> 853 <211> 118 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28179..28532) <400> 853 Met Asn Leu Leu Val Lys Arg Asn Val Glu Glu Phe Leu Arg Leu Leu 1 5 10 15 Gly Asn Asp Phe Tyr Leu Phe Asp Asn Arg Val Glu Ile Asp Phe Asn 20 25 30 Gly Phe Ser Phe Phe Ile Glu Ile Ile Asp Asn Asn Val Phe Val Thr 35 40 45 Phe Ala Leu Glu Tyr Asn Glu Asn Ala Phe Phe Ser Phe Phe Ser Ala 50 55 60 Leu Ala Pro Glu Arg Thr Gln Gly Val Ile Glu His Ile Phe Val Tyr 65 70 75 80 Asp Asn Lys Leu Cys Leu Ser Cys Leu Leu Thr Asn Ile Asp Val Phe 85 90 95 Phe Leu Met Asn Thr Phe Gln Gln His Val Gln Ile Ile Glu Arg Val 100 105 110 Arg Arg Met Thr Ser * 115 <210> 854 <211> 100 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28717..29016) <400> 854 Met Glu Ala Ala Asn Leu Ser Pro Ser Gly Ala Val Met Pro Leu Ala 1 5 10 15 Thr Ser Leu Ser Gly Asn Asn Ser Val Asp Glu Lys Thr Gly Val Ile 20 25 30 Lys Pro Glu Asn Gly Thr Asn Arg Thr Val Arg Val Ile Ala Gly Leu 35 40 45 Ala Leu Thr Thr Thr Ala Leu Ala Ala Leu Gly Thr Gly Ile Ala Ala 50 55 60 Ala Cys Ser Glu Thr Ser Ser Thr Glu Tyr Leu Ala Leu Gly Ile Thr 65 70 75 80 Ser Gly Val Leu Gly Thr Leu Thr Ala Val Gly Gly Ala Leu Ala Met 85 90 95 Lys Tyr Ala * <210> 855 <211> 143 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29049..29477) <400> 855 Met Asp Val Leu Cys Pro Cys Leu Phe His Lys Lys Arg Leu Thr Val 1 5 10 15 Asn Met Asn Asn Ile Asn Gln Ser Glu Asn Ile Asn Ile Gln Leu Asn 20 25 30 Lys Ala Pro Gln Thr Asn Phe Val Asp Glu His Thr Ser Leu Ala Ser 35 40 45 Ala Pro Ser Ala Ala Gly Ala Ala Gln Phe Leu Asp Gln Leu Leu Pro 50 55 60 Lys Thr Ala Gly Val Ser Ser Pro Glu Gln Val Leu Ile Glu Glu Ile 65 70 75 80 Lys Lys Arg His Leu Ala Thr Met Asn Ser Asp Leu Ser Phe Asp Ala 85 90 95 Leu Ser Ala Gly Gly Leu Ser Pro Glu Asp Val Leu Thr Leu Gln Lys 100 105 110 Asn Val Leu Asn Ala Asn Val Asn Val Asp Val Val Ser Lys Leu Ala 115 120 125 Ser Leu Leu Ser Thr Ser Val Thr Lys Leu Val Ser Met Gln * 130 135 140 <210> 856 <211> 191 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29480..30052) <400> 856 Met Lys Lys His Ile Lys Asn Leu Phe Leu Leu Ala Ala Ile Cys Leu 1 5 10 15 Thr Val Ala Cys Lys Glu Gln Leu Tyr Thr Gly Leu Thr Glu Lys Glu 20 25 30 Ala Asn Gln Met Gln Ala Leu Leu Leu Ser Asn Asp Val Asn Val Ser 35 40 45 Lys Glu Met Asp Lys Ser Gly Asn Met Thr Leu Ser Val Glu Lys Glu 50 55 60 Asp Phe Val Arg Ala Ile Thr Ile Leu Asn Asn Asn Gly Phe Pro Lys 65 70 75 80 Lys Lys Phe Ala Asp Ile Glu Val Ile Phe Pro Pro Ser Gln Leu Val 85 90 95 Ala Ser Pro Ser Gln Glu Asn Ala Lys Ile Asn Tyr Leu Lys Glu Gln 100 105 110 Asp Ile Glu Arg Leu Leu Ser Lys Ile Pro Gly Val Ile Asp Cys Ser 115 120 125 Val Ser Leu Asn Val Asn Asn Asn Glu Ser Gln Pro Ser Ser Ala Ala 130 135 140 Val Leu Val Ile Ser Ser Pro Glu Val Asn Leu Ala Pro Ser Val Ile 145 150 155 160 Gln Ile Lys Asn Leu Val Lys Asn Ser Val Asp Asp Leu Lys Leu Glu 165 170 175 Asn Ile Ser Val Val Ile Lys Ser Ser Ser Gly Gln Asp Gly * 180 185 190 <210> 857 <211> 152 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30058..30513) <400> 857 Met Asn Asn Asn Asn Gly Ile Ala Lys Asn Asp Cys Asp Trp Leu Thr 1 5 10 15 Ala Leu Asp Phe Val Lys Asp Val Asn Gly Ser Pro Thr His Leu Thr 20 25 30 Phe Tyr Ile Tyr Gln Lys Asn Ala Phe Leu His Asp Phe Gly Asn Tyr 35 40 45 Trp Val Leu Tyr Ile Glu Leu Ser Gly Asp Phe Arg Gln Val Pro Thr 50 55 60 Asp Thr Phe Ile Arg Leu Cys Asn Ile Leu Ala Val Ser Asn Glu Tyr 65 70 75 80 Lys Gln Met Gly Ile Phe Leu Ser Asn Lys Lys Trp Tyr Leu Cys Gln 85 90 95 Ile Phe His Lys Asp Asn Asn His Arg Ala Asn Met Ser Lys Ala Ile 100 105 110 Met Gln His Thr Leu Ala Ser Leu Leu Asp Lys Gln Phe Asp Lys Leu 115 120 125 Glu Gln Leu Ser Ser Ser Asp Thr Met Met Pro Pro Thr His Leu Phe 130 135 140 Ser Asp Ile Gly Arg Ile Val * 145 150 <210> 858 <211> 513 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30513..32051) <400> 858 Met Lys Lys Ile Ser Phe Phe Ile Phe Thr Ala Leu Phe Cys Cys Ser 1 5 10 15 Ala Gln Ala Ala Pro Ser Ser Leu Glu Lys Arg Leu Gly Lys Ser Glu 20 25 30 Tyr Phe Ile Ile Thr Lys Ser Ser Pro Val Arg Ala Ile Leu Asn Asp 35 40 45 Phe Ala Ala Asn Tyr Ser Ile Pro Val Phe Ile Ser Ser Ser Val Asn 50 55 60 Asp Asp Phe Ser Gly Glu Ile Lys Asn Glu Lys Pro Val Lys Val Leu 65 70 75 80 Glu Lys Leu Ser Lys Leu Tyr His Leu Thr Trp Tyr Tyr Asp Glu Asn 85 90 95 Ile Leu Tyr Ile Tyr Lys Thr Asn Glu Ile Ser Arg Ser Ile Ile Thr 100 105 110 Pro Thr Tyr Leu Asp Ile Asp Ser Leu Leu Lys Tyr Leu Ser Asp Thr 115 120 125 Ile Ser Val Asn Lys Asn Ser Cys Asn Val Arg Lys Ile Thr Thr Phe 130 135 140 Asn Ser Ile Glu Val Arg Gly Val Pro Glu Cys Ile Lys Tyr Ile Thr 145 150 155 160 Ser Leu Ser Glu Ser Leu Asp Lys Glu Ala Gln Ser Lys Ala Lys Asn 165 170 175 Lys Asp Val Val Lys Val Phe Lys Leu Asn Tyr Ala Ser Ala Thr Asp 180 185 190 Ile Thr Tyr Lys Tyr Arg Asp Gln Asn Val Val Val Pro Gly Val Val 195 200 205 Ser Ile Leu Lys Thr Met Ala Ser Asn Gly Ser Leu Pro Ser Thr Gly 210 215 220 Lys Gly Ala Val Glu Arg Ser Gly Asn Leu Phe Asp Asn Ser Val Thr 225 230 235 240 Ile Ser Ala Asp Pro Arg Leu Asn Ala Val Val Val Lys Asp Arg Glu 245 250 255 Ile Thr Met Asp Ile Tyr Gln Gln Leu Ile Ser Glu Leu Asp Ile Glu 260 265 270 Gln Arg Gln Ile Glu Ile Ser Val Ser Ile Ile Asp Val Asp Ala Asn 275 280 285 Asp Leu Gln Gln Leu Gly Val Asn Trp Ser Gly Thr Leu Asn Ala Gly 290 295 300 Gln Gly Thr Ile Ala Phe Asn Ser Ser Thr Ala Gln Ala Asn Ile Ser 305 310 315 320 Ser Ser Val Ile Ser Asn Ala Ser Asn Phe Met Ile Arg Val Asn Ala 325 330 335 Leu Gln Gln Asn Ser Lys Ala Lys Ile Leu Ser Gln Pro Ser Ile Ile 340 345 350 Thr Leu Asn Asn Met Gln Ala Ile Leu Asp Lys Asn Val Thr Phe Tyr 355 360 365 Thr Lys Val Ser Gly Glu Lys Val Ala Ser Leu Glu Ser Ile Thr Ser 370 375 380 Gly Thr Leu Leu Arg Val Thr Pro Arg Ile Leu Asp Asp Ser Ser Asn 385 390 395 400 Ser Leu Thr Gly Lys Arg Arg Glu Arg Val Arg Leu Leu Leu Asp Ile 405 410 415 Gln Asp Gly Asn Gln Ser Thr Asn Gln Ser Asn Ala Gln Asp Ala Ser 420 425 430 Ser Thr Leu Pro Glu Val Gln Asn Ser Glu Met Thr Thr Glu Ala Thr 435 440 445 Leu Ser Ala Gly Glu Ser Leu Leu Leu Gly Gly Phe Ile Gln Asp Lys 450 455 460 Glu Ser Ser Ser Lys Asp Gly Ile Pro Leu Leu Ser Asp Ile Pro Val 465 470 475 480 Ile Gly Ser Leu Phe Ser Ser Thr Val Lys Gln Lys His Ser Val Val 485 490 495 Arg Leu Phe Leu Ile Lys Ala Thr Pro Ile Lys Ser Ala Ser Ser Glu 500 505 510 * <210> 859 <211> 152 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32065..32520) <400> 859 Met Ser Arg Lys Phe Ser Ser Leu Glu Asp Ile Tyr Asp Phe Tyr Gln 1 5 10 15 Asp Gly Gly Thr Leu Ala Ser Leu Thr Asn Leu Thr Gln Gln Asp Leu 20 25 30 Asn Asp Leu His Ser Tyr Ala Tyr Thr Ala Tyr Gln Ser Gly Asp Val 35 40 45 Ile Thr Ala Arg Asn Leu Phe His Leu Leu Thr Tyr Leu Glu His Trp 50 55 60 Asn Tyr Asp Tyr Thr Leu Ser Leu Gly Leu Cys His Gln Arg Leu Ser 65 70 75 80 Asn His Glu Asp Ala Gln Leu Cys Phe Ala Arg Cys Ala Thr Leu Val 85 90 95 Met Gln Asp Pro Arg Ala Ser Tyr Tyr Ser Gly Ile Ser Tyr Leu Leu 100 105 110 Val Gly Asn Lys Lys Met Ala Lys Lys Ala Phe Lys Ala Cys Leu Met 115 120 125 Trp Cys Asn Glu Lys Glu Lys Tyr Thr Thr Tyr Lys Glu Asn Ile Lys 130 135 140 Lys Leu Leu Gly Asn Thr Glu * 145 150 <210> 860 <211> 138 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32904..33317) <400> 860 Met Glu Ser Lys Asn Lys Asn Gly Asp Tyr Val Ile Pro Asp Ser Val 1 5 10 15 Lys Asn Tyr Asp Gly Glu Pro Leu Tyr Ile Leu Val Ser Leu Trp Cys 20 25 30 Lys Leu Gln Glu Lys Trp Ile Ser Arg Asn Asp Ile Ala Glu Ala Phe 35 40 45 Gly Ile Asn Leu Arg Arg Ala Ser Phe Ile Ile Thr Tyr Ile Ser Arg 50 55 60 Arg Lys Glu Lys Ile Ser Phe Arg Val Arg Tyr Val Ser Tyr Gly Asn 65 70 75 80 Leu His Tyr Lys Arg Leu Glu Ile Phe Ile Tyr Asp Val Asn Leu Glu 85 90 95 Ala Val Pro Ile Glu Ser Pro Gly Thr Thr Gly Pro Lys Arg Lys Thr 100 105 110 Tyr Arg Val Gly Asn Gly Ile Val Gly Gln Ser Asn Ile Trp Asn Glu 115 120 125 Met Ile Met Arg Arg Lys Lys Glu Ser * 130 135 <210> 861 <211> 124 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33372..33743) <400> 861 Met Ile Met Lys Asp Gly Ile Tyr Ser Ile Ile Phe Ile Ser Asn Glu 1 5 10 15 Asp Ser Cys Gly Glu Gly Ile Leu Ile Lys Asn Gly Asn Met Ile Thr 20 25 30 Gly Gly Asp Ile Ala Ser Val Tyr Gln Gly Val Leu Ser Glu Asp Glu 35 40 45 Asp Ile Ile Leu His Val His Arg Tyr Asn Tyr Glu Ile Pro Ser Val 50 55 60 Leu Asn Ile Glu Gln Asp Tyr Gln Leu Val Ile Pro Lys Lys Val Leu 65 70 75 80 Ser Asn Asp Asn Asn Leu Thr Leu His Cys His Val Arg Gly Asn Glu 85 90 95 Lys Leu Phe Val Asp Val Tyr Ala Lys Phe Ile Glu Pro Leu Val Ile 100 105 110 Lys Asn Thr Gly Met Pro Gln Val Tyr Leu Lys * 115 120 <210> 862 <211> 153 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33939..34397) <400> 862 Met Lys Lys Ile Ile Leu Ser Ile Ile Leu Ile Ser Asn Tyr Cys Tyr 1 5 10 15 Ala Ser Asp Cys Phe Glu Ile Thr Gly Lys Ala Tyr Asn Ile Asp Pro 20 25 30 Leu Ile Leu Lys Ala Ile Ala Trp Asn Glu Ser Lys Cys Lys Ser Gly 35 40 45 Ile Lys Ser Lys Thr Asn Lys Asn Gly Thr Tyr Asp Ile Gly Ile Met 50 55 60 Gln Ile Asn Ser Ser His Leu Asp Leu Leu Ser Lys Phe Asn Ile Ser 65 70 75 80 Glu Asp Asp Leu Leu Asn Asp Ala Cys Ile Asn Ile Ser Val Ala Gly 85 90 95 Tyr Ile Leu Ala Ser Asn Ile Lys Ser Arg Gly Asn Thr Trp Asp Ala 100 105 110 Val Gly Ala Tyr Asn Ala Gly Tyr Phe Asn Thr Pro Asn Ala Val Glu 115 120 125 Leu Arg Arg Gln Tyr Ala Met Lys Ile Tyr Lys Thr Tyr Asn Lys Leu 130 135 140 Lys Asn Asn Glu Gln Ile Ile Asp * 145 150 <210> 863 <211> 346 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34394..35431) <400> 863 Met Ser Glu Lys Thr Glu Lys Pro Thr Pro Lys Lys Leu Arg Asp Leu 1 5 10 15 Lys Lys Lys Gly Asp Val Thr Lys Ser Glu Glu Val Met Ala Ala Val 20 25 30 Gln Ser Leu Ile Leu Phe Ser Phe Phe Ser Leu Tyr Gly Met Ser Phe 35 40 45 Phe Val Asp Ile Val Gly Leu Val Asn Thr Thr Ile Asp Ser Leu Asn 50 55 60 Arg Pro Phe Leu Tyr Ala Ile Arg Glu Ile Leu Gly Ala Val Leu Asn 65 70 75 80 Ile Phe Leu Leu Tyr Ile Leu Pro Ile Ser Leu Ile Val Phe Val Gly 85 90 95 Thr Val Thr Thr Gly Val Ser Gln Ile Gly Phe Ile Phe Ala Val Glu 100 105 110 Lys Ile Lys Pro Ser Ala Gln Lys Ile Ser Val Lys Asn Asn Leu Lys 115 120 125 Asn Ile Phe Ser Val Lys Ser Ile Phe Glu Leu Leu Lys Ser Val Phe 130 135 140 Lys Leu Val Ile Ile Val Leu Ile Phe Tyr Phe Met Gly His Ser Tyr 145 150 155 160 Ala Asn Glu Phe Ala Asn Phe Thr Gly Leu Asn Ala Tyr Gln Ala Leu 165 170 175 Val Val Val Ala Phe Phe Val Phe Leu Leu Trp Lys Gly Val Leu Phe 180 185 190 Gly Tyr Leu Leu Phe Ser Val Phe Asp Phe Trp Phe Gln Lys His Glu 195 200 205 Gly Leu Lys Lys Met Lys Met Ser Lys Asp Glu Val Lys Arg Glu Ala 210 215 220 Lys Asp Thr Asp Gly Asn Pro Glu Ile Lys Gly Glu Arg Arg Arg Leu 225 230 235 240 His Ser Glu Ile Gln Ser Gly Ser Leu Ala Asn Asn Ile Lys Lys Ser 245 250 255 Thr Val Ile Val Lys Asn Pro Thr His Ile Ala Ile Cys Leu Tyr Tyr 260 265 270 Lys Leu Gly Glu Thr Pro Leu Pro Leu Val Ile Glu Thr Gly Lys Asp 275 280 285 Ala Lys Ala Leu Gln Ile Ile Lys Leu Ala Glu Leu Tyr Asp Ile Pro 290 295 300 Val Ile Glu Asp Ile Pro Leu Ala Arg Thr Leu Tyr Lys Asn Ile His 305 310 315 320 Lys Gly Gln Tyr Ile Thr Glu Asp Phe Phe Glu Pro Val Ala Gln Leu 325 330 335 Ile Arg Ile Ala Ile Asp Leu Asp Tyr * 340 345 <210> 864 <211> 259 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35424..36200) <400> 864 Met Asn Glu Ile Met Thr Val Ile Val Ser Ser Phe Tyr Cys Ile Leu 1 5 10 15 Arg Pro Leu Gly Met Phe Ile Ile Leu Pro Ile Phe Ser Thr Gly Val 20 25 30 Leu Leu Ser Asn Phe Ile Arg Asn Ser Ile Met Ile Ala Phe Thr Leu 35 40 45 Pro Ile Ile Val Glu Asn Tyr Thr Phe Ser Glu Lys Leu Pro Ser Gly 50 55 60 Ile Phe Gln Leu Thr Gly Ile Ala Leu Lys Glu Ile Ser Ile Gly Phe 65 70 75 80 Phe Ile Gly Leu Ser Phe Thr Ile Leu Phe Trp Ala Ile Asp Ala Ala 85 90 95 Gly Gln Ile Ile Asp Thr Leu Arg Gly Ser Thr Ile Ser Ser Ile Phe 100 105 110 Asn Pro Ser Ile Ser Asp Ser Ser Ser Ile Thr Gly Val Ile Leu Tyr 115 120 125 Gln Phe Ile Ser Val Ile Phe Val Ile His Gly Gly Ile Gln Ser Ile 130 135 140 Leu Asp Lys Leu Tyr Leu Ser Tyr Glu Ile Leu Pro Leu Gln Ala Asp 145 150 155 160 Ile Ala Phe Asn Arg Ala Leu Ile Asp Phe Leu Phe Ser Leu Trp Asp 165 170 175 Ser Phe Ile Lys Leu Met Leu Ser Phe Ser Val Pro Met Ile Ile Gly 180 185 190 Ile Phe Leu Cys Asp Met Gly Phe Gly Phe Leu Asn Lys Thr Ala Pro 195 200 205 Gln Leu Asn Val Phe Thr Leu Ser Leu Pro Val Lys Ser Leu Ile Ala 210 215 220 Ile Phe Ile Leu Leu Leu Val Ile His Val Phe Pro Asp Phe Ile Thr 225 230 235 240 Ala Asn Ile His Ser Asp Ile Ile Asp Arg Ser Leu Pro Ser Met Ile 245 250 255 Asn Glu * <210> 865 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36200..36469) <400> 865 Met Asp Thr Gly Tyr Phe Val Gln Leu Cys Val Gln Thr Phe Trp Ile 1 5 10 15 Ile Phe Ile Leu Ser Leu Pro Thr Val Ile Ala Ala Ser Val Ile Gly 20 25 30 Ile Ile Ile Ser Leu Val Gln Ala Ile Thr Gln Leu Gln Asp Gln Thr 35 40 45 Leu Pro Phe Leu Leu Lys Ile Ile Ala Val Phe Ala Thr Leu Ala Leu 50 55 60 Thr Tyr His Trp Met Gly Thr Thr Ile Ile Asn Phe Ser Ser Ile Ile 65 70 75 80 Phe Glu Met Ile Pro Lys Val Asn Gly * 85 <210> 866 <211> 218 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36469..37122) <400> 866 Met Ser Gln Leu Met Thr Ile Gly Ser Gln Pro Ile Phe Leu Ile Ile 1 5 10 15 Val Phe Phe Leu Leu Ser Leu Leu Pro Ile Phe Val Gly Ile Gly Thr 20 25 30 Ser Phe Leu Lys Ile Ser Ile Val Leu Gly Ile Leu Lys Asn Ala Leu 35 40 45 Gly Ile Gln Gln Val Pro Pro Asn Met Ala Leu Thr Ser Val Ser Leu 50 55 60 Ile Leu Thr Met Phe Ile Met Ser Pro Ile Ile Leu Gln Ile Asn Asp 65 70 75 80 Asn Ile Ser Gln Glu Pro Ile Asn Tyr Thr Asp Ser Asp Phe Phe Gln 85 90 95 Lys Val Asp Glu Lys Ile Leu Ser Pro Tyr Arg Gly Phe Leu Glu Lys 100 105 110 Asn Thr Glu Lys Asp Asn Val Glu Phe Phe Glu Arg Ala Ala Gln Lys 115 120 125 Lys Leu Gly Asn Glu Thr Ile Leu Lys Lys Asp Ser Leu Phe Ile Leu 130 135 140 Leu Pro Ala Phe Thr Met Gly Gln Leu Glu Ala Ala Phe Lys Ile Gly 145 150 155 160 Phe Leu Leu Tyr Leu Pro Phe Ile Ala Ile Asp Leu Ile Ile Ser Asn 165 170 175 Ile Leu Leu Ala Leu Gly Met Met Met Val Ser Pro Val Thr Ile Ser 180 185 190 Ile Pro Phe Lys Ile Leu Leu Phe Ile Leu Val Gly Gly Trp Gln Lys 195 200 205 Leu Phe Glu Phe Leu Leu Val Val Asn * 210 215 <210> 867 <211> 232 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37127..37822) <400> 867 Met Ile Tyr Phe Leu Thr Asp Leu Ile Lys Phe Tyr Cys Leu Met Lys 1 5 10 15 Leu Tyr Glu Phe Lys Asn Ile Lys Ile Asp Leu Val Leu Thr Glu Asp 20 25 30 Ile Ile Pro Glu Asp Lys Leu Gln Glu Ile Ile Gln Ser Asp Asp Ile 35 40 45 Ile Lys Leu Ala Arg Lys Lys Thr Tyr Glu His Leu Leu Arg Ala Arg 50 55 60 Arg Lys Ser Lys Glu Leu Lys Thr Glu Ser Arg Lys Lys Ile Ala Arg 65 70 75 80 Lys Met Ile Leu Met Arg Glu Arg Ile Arg Lys Asn Asn Lys Ile Lys 85 90 95 Leu Asp Lys Glu Val Asn Gln Ser Ile Lys Trp Val Lys Asp Ile Gln 100 105 110 Ala Ile Glu Leu Val Leu Met Gln Asp Ile Met Asn Lys Ile His Leu 115 120 125 Ser Leu Thr Asn Ala Leu His Ser Leu Asp Thr Ser Ser Arg Ile Asn 130 135 140 Trp Asp Asp Leu Leu Asn Glu Val Val Arg Glu Thr Leu Ser Asn Asn 145 150 155 160 Asn Ile Val Gly Ala Ile Lys Ile Thr Lys Asn Pro Asp Ile Lys Leu 165 170 175 Asp Pro Gly Glu Ala Asn Asn Ile Gln Leu Ile Asn Asp Ala Asn Thr 180 185 190 Pro His Asn Lys Ile Ile Ile Glu Asn Glu Tyr Ile Arg Ile Thr Leu 195 200 205 Asp Pro Leu Glu Gln Ile Ser Ile Leu Leu Asn Ser Phe Lys Asp Asn 210 215 220 Tyr Leu Ser Ile Ile Gln Glu * 225 230 <210> 868 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37767..38366) <400> 868 Met Thr Ile Phe Asn Lys Ile Asp Tyr Asn Tyr Tyr Lys Leu Ile Asn 1 5 10 15 Tyr Pro Ile Met Met Val His Asp Glu Trp Leu Gly Asp Leu Thr Gly 20 25 30 Val Asn Gln Val Ser Phe Arg Arg Leu Arg Glu Thr Ser Ser Thr Arg 35 40 45 Asn Gln Leu Asn Lys Ile Leu Arg Gln Glu Ile His Asp Lys Ile Ser 50 55 60 Gly Val Glu Leu Ser Asp Ile Asn Lys Glu Gly Phe Leu Tyr Gln Ser 65 70 75 80 Ile Gly Lys Ile Arg Leu Leu Ala Leu Ser Ser Ala Leu Phe Asp Ile 85 90 95 Gln Cys Pro Asp Tyr Ile Phe Ser Arg Leu Tyr Arg Glu Thr Leu Ile 100 105 110 Arg Glu Ile Gly Tyr Gln Asn Val Lys Gln Leu Ser Phe Tyr Trp Gln 115 120 125 Gly Gly Gln Cys Lys Pro Glu Tyr Gly Glu Glu Arg Phe Cys Ala Glu 130 135 140 Leu Ile Lys Tyr Gly Ala Gly Asn Leu Glu Trp Leu Phe Ala Asp Asn 145 150 155 160 Pro Leu Trp Thr Ile Val Lys Tyr Leu Leu Pro Lys Ser Gly Glu Ile 165 170 175 Lys Pro Thr His Ile Asn Asp Leu Phe Leu Asn Arg Leu Asn Lys Ile 180 185 190 Leu Leu Pro Tyr Glu Thr Leu * 195 <210> 869 <211> 108 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38363..38686) <400> 869 Met Ser Ile Val Ser Gln Thr Arg Asn Lys Glu Leu Leu Asp Lys Lys 1 5 10 15 Ile Arg Ser Glu Ile Glu Ala Ile Lys Lys Ile Ile Ala Glu Phe Asp 20 25 30 Val Val Lys Glu Ser Val Asn Glu Leu Ser Glu Lys Ala Lys Thr Asp 35 40 45 Pro Gln Ala Ala Glu Lys Leu Asn Lys Leu Ile Glu Gly Tyr Thr Tyr 50 55 60 Gly Glu Glu Arg Lys Leu Tyr Asp Ser Ala Leu Ser Lys Ile Glu Lys 65 70 75 80 Leu Ile Glu Thr Leu Ser Pro Ala Arg Ser Lys Ser Gln Ser Thr Met 85 90 95 Asn Gln Arg Asn Arg Asn Asn Arg Lys Ile Val * 100 105 <210> 870 <211> 73 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38690..38908) <400> 870 Met Ile Thr Ile Thr Glu Leu Glu Asp Glu Ile Ile Lys Asn Lys Glu 1 5 10 15 Ala Ala Asn Val Phe Ile Glu Lys Ile Asn Asp Lys Lys Asn Glu Ile 20 25 30 His Glu Lys Met Lys His Pro Leu Asp Lys Val Thr Tyr Asp Glu Ala 35 40 45 Lys Glu Leu Leu Ile Ala Cys Asp Ala Ala Ile Arg Thr Ile Glu Ile 50 55 60 Met Arg Ile Arg Ile Asn Asn Lys * 65 70 <210> 871 <211> 130 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38923..39312) <400> 871 Met Arg Arg Leu Phe Ile Met Asn Met Glu Asn Asn Ser His Thr Thr 1 5 10 15 Ser Pro Tyr Ile Gln Leu Ile Glu Gln Ile Ala Val Leu Gln Gln Glu 20 25 30 Ala Lys Arg Leu Arg Glu Gln Glu Val Gln Ser Val Ile Glu Ser Ile 35 40 45 Gln Lys Gln Ile Thr Tyr Tyr Asn Ile Thr Leu Gln Glu Leu Gly Tyr 50 55 60 Thr Asn Val Pro Asp Asp Gly Leu Ala Arg Arg Asn Ser Ser Lys Gly 65 70 75 80 Val Tyr Tyr Arg Asn Glu Glu Gly Gln Thr Trp Ser Gly Val Gly Arg 85 90 95 Gln Pro Arg Trp Leu Lys Glu Ala Leu Leu Asn Gly Met Lys Lys Glu 100 105 110 Asp Phe Leu Val Lys Asp Thr Glu Glu Glu Ile Ile Pro Leu Lys Asn 115 120 125 Ile * <210> 872 <211> 42 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39863..39988) <400> 872 Met Tyr Gly Arg Ser Ser Phe Ala Glu Trp Ile Trp Thr Ile Leu Leu 1 5 10 15 Asn Thr Asn Gly Thr Val Met Arg Glu Glu Thr Asn Ala Val Thr Val 20 25 30 Gln Leu Phe Val Pro Cys Ser Phe Leu * 35 40 <210> 873 <211> 399 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40557..41753) <400> 873 Met Ile Leu Val Ala Lys Leu Phe Ile Thr Asn Gln Ile Gly Glu Ser 1 5 10 15 Leu Met Ile Asn Gly Leu Asn Asn Asp Ser Ala Ser Leu Val Leu Asp 20 25 30 Ala Ala Met Lys Val Asn Ser Gly Phe Lys Lys Ser Trp Asp Glu Met 35 40 45 Ser Cys Ala Glu Lys Leu Phe Lys Val Leu Ser Phe Gly Leu Trp Asn 50 55 60 Pro Thr Tyr Ser Arg Ser Glu Arg Gln Ser Phe Gln Glu Leu Leu Thr 65 70 75 80 Val Leu Glu Pro Val Tyr Pro Leu Pro Asn Glu Leu Gly Arg Val Ser 85 90 95 Ala Arg Phe Ser Asp Gly Ser Ser Leu Arg Ile Ser Val Thr Asn Ser 100 105 110 Glu Leu Val Glu Ala Glu Ile Arg Thr Ala Asn Asn Glu Lys Ile Thr 115 120 125 Val Leu Leu Glu Ser Asn Glu Gln Asn Arg Leu Leu Gln Ser Leu Pro 130 135 140 Ile Asp Arg His Met Pro Tyr Ile Gln Val His Arg Ala Leu Ser Glu 145 150 155 160 Met Asp Leu Thr Asp Thr Thr Ser Met Arg Asn Leu Leu Gly Phe Thr 165 170 175 Ser Lys Leu Ser Thr Thr Leu Ile Pro His Asn Ala Gln Thr Asp Pro 180 185 190 Leu Ser Gly Pro Thr Pro Phe Ser Ser Ile Phe Met Asp Thr Cys Arg 195 200 205 Gly Leu Gly Asn Ala Lys Leu Ser Leu Asn Gly Val Asp Ile Pro Ala 210 215 220 Asn Ala Gln Lys Leu Leu Arg Asp Ala Leu Gly Leu Lys Asp Thr His 225 230 235 240 Ser Ser Pro Thr Arg Asn Val Ile Asp His Gly Ile Ser Arg His Asp 245 250 255 Ala Glu Gln Ile Ala Arg Glu Ser Ser Gly Ser Asp Lys Gln Lys Ala 260 265 270 Glu Val Val Glu Phe Leu Cys His Pro Glu Ala Ala Thr Ala Ile Cys 275 280 285 Ser Ala Phe Tyr Gln Ser Phe Asn Val Pro Ala Leu Thr Leu Thr His 290 295 300 Glu Arg Ile Ser Lys Ala Ser Glu Tyr Asn Ala Glu Arg Ser Leu Asp 305 310 315 320 Thr Pro Asn Ala Cys Ile Asn Ile Ser Ile Ser Gln Ser Ser Asp Gly 325 330 335 Asn Ile Tyr Val Thr Ser His Thr Gly Val Leu Ile Met Ala Pro Glu 340 345 350 Asp Arg Pro Asn Glu Met Gly Met Leu Thr Asn Arg Thr Ser Tyr Glu 355 360 365 Val Pro Gln Gly Val Lys Cys Ile Ile Asp Glu Met Val Ser Ala Leu 370 375 380 Gln Pro Arg Tyr Ala Ala Ser Glu Thr Tyr Leu Gln Asn Thr * 385 390 395 <210> 874 <211> 273 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(41881..42699) <400> 874 Met Lys Arg Lys Pro Leu Ile Ala Phe Phe Ile Ala Ile Phe Ile Ala 1 5 10 15 Leu Thr Ile Leu Ile Leu Phe Pro Phe Asn Cys Thr Tyr Lys Lys Ser 20 25 30 Pro Gln Glu His Ser Leu Ser Phe Ile Lys Gln Leu Pro Asn Thr Val 35 40 45 Asn Leu Ser Ser Leu Thr Tyr Asn Lys Glu Asp Asp Phe Leu Tyr Ala 50 55 60 Thr Gln Asn Ser Pro Ala Gln Leu Leu Lys Ile Thr Lys Ser Gly Asp 65 70 75 80 Ile Met Asp Arg Ala Pro Leu Pro Phe Ile Ser Asp Ala Glu Thr Ile 85 90 95 Glu His Ile Gln Gly Asn Ile Phe Ala Ala Val Asp Glu Lys Thr Ser 100 105 110 Glu Leu Phe Phe Phe Thr Val Thr Lys Asp Met His Ile Ser Phe Arg 115 120 125 Asn Lys Ile Gln Leu Glu Lys Phe Asn Lys Lys Asn Arg Gly Phe Glu 130 135 140 Gly Leu Ala Trp Lys Ala Asp Asp Arg Met Leu Phe Val Ala Lys Glu 145 150 155 160 Arg Arg Pro Ser Lys Ile Phe Ile Tyr Gln Leu Ser Pro Asp Leu Leu 165 170 175 Ser Val Lys Gln Ala Thr Ile Pro Glu Ala Leu Asn Asp Ile Arg Val 180 185 190 Asn Asp Ile Ser Gly Leu Ala Phe Asn Asn Glu Ser Leu Met Ile Leu 195 200 205 Ser Asp Glu Ser Arg Lys Leu Leu Lys Phe Asn Leu Thr Glu Met Ser 210 215 220 Phe Ile Glu Met Leu Asp Leu Thr Lys Gly Asn His Ser Leu Thr Ser 225 230 235 240 Asp Leu Pro Gln Pro Glu Gly Ile Val Thr Leu Pro Asp Glu Ser Ile 245 250 255 Tyr Val Ala Ser Glu Pro Asp Ile Leu Ala Lys Phe Val Pro Asn Lys 260 265 270 * <210> 875 <211> 78 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43013..43246) <400> 875 Leu Phe Gln Asn Glu Ile Lys Asp Lys Phe Lys Thr Gly Leu Ala Tyr 1 5 10 15 Val Arg Gly Pro Glu Lys Ser Gly Ser Ser Ala Gln Asn Ala Gly Ser 20 25 30 Glu Gly Gly Lys Lys Cys Ala Gly Arg Ser Arg Arg Leu Ser Arg Asp 35 40 45 Val Arg Leu Arg Asn Thr Ser Leu Ile Lys Arg Val Ser Met Met Ile 50 55 60 Leu Val Ala Asp Gln Arg Asn Tyr Ile Arg Arg Lys Gln * 65 70 75 <210> 876 <211> 39824 <212> DNA <213> Escherichia coli O157:H7 <400> 876 ggaaactgat ggtaaggcct ttcctcagcc cacaggtgtt gcgttaccag tacaggaggc 60 tgcaacacag gaagatatta aaacagaaac ggtggcggac attgtgcagt cgctgccatc 120 gtttactgaa acgcgagcgg atgacctggt tttaccatcg ctgcatatgg caaaccgcga 180 actgcgtcgg gcgaaaaatc atgtccagaa gtgggagcga gtctgcgccg cgctgcggga 240 gctgaacaag caccgggata ttgttcgaca gattttcgat tcctccagtc gtattgtgtc 300 ggaaaagtga ttgccggagg cacctatggc aaaagtattt acaccagaag agcgggaaaa 360 aattaaaggg caggttgttg aacttgtacg tctgagcggt cgcgagacgt tacgggctct 420 ggaggctaaa accggtgcat caaggtatta cataagcact ctcgccagag aactggtcgc 480 cagtggtgat gtttacaatt caggctacgg attattcccg tctgagcagg cgcgtaaaga 540 ctggcaaaac gcccgcaaaa aactatcaag ggcaaaggtg aagaaaccgg ttgtggttga 600 tccggatctt atctggtcat taccagacgg agaaatacgc cgctacgaca ggcgtctgaa 660 cataatctgt agcgagtgcc ggaagagcga agctatgcag cgtgtactgg ctttctatca 720 gggtaatttt cagaaggtgc tgttgtgagc caaattaaca atcggaactt cgtgaagaga 780 aagcataatc caaatctgaa taattaagtt cagcactgta aataaaattt aatccttaac 840 tggaggtata tttatgttaa atacacagaa agccattaat gcggaaaaat ataacgagtg 900 ggcaagaaaa ttctctgagc agatttttaa aattactggc gatgagaatg cggcaaaaaa 960 tgaattagaa ccgtggacgc ctgaaggagc cgacccaaat tattgctgga gggaggttga 1020 tccagttgat gctgcaaatg aagctatgag ttatcacaac gattaatgtc aggaggccgc 1080 ccgaaagggc ggtaatgaat ggtcacatta tttagaaaaa atatccgcga aagagtagaa 1140 caacagaatt tctgtttctc attctgttta tcgtgttgat gataccgata tccccgttaa 1200 tcctagtctg gataatcgga aaaataattg agccagttat tgaattgtat aacgacgtgg 1260 tatgggcgtc attcaacaca ctgcacaata aaattaatcc gtataaggaa aactgatatg 1320 gcaactttga caaaaaaaga acgggcatgg ttgaacgaat tacaggaagt tcttgatcgc 1380 tgtccatcac cgaaaaaaat tggcttttac accattggcg ataaaagcat ttacctgtat 1440 gacctacgcc gcatggatga aatcatggag gctcttgata atcgttcgtc gatggattgg 1500 tgtgttgctg ttcatgatat gaatgcaggg tttgatgaaa agattttgtt cccctcatca 1560 gttgaaagca ctgcgggtta aggagtaaca catgaccact attaccaaag aacgtattga 1620 attgttcatt aaaaatccgg ttgaaaacgg gcttacccgt ggtgaacaaa tggaactggc 1680 acggattgcg ctggcatcgc tggaagcaga gccagttggt gatttttatg aatacaaacc 1740 ggatgactgg tagcagcgtt cggctggaga taaagcgcca aaatggacgc caccctatgc 1800 cgtttttcca gcgcccgtag tgccggaaga aatggatttg cttacatgcc atctcgatgg 1860 tgtaactgaa acatatgctg agggatggaa cgcttgccgc gctgccctgc ttcagggcaa 1920 aggggagccc gggaaacaag ttcgcgaatt gacaatgctg gttaaacaat tggttagtca 1980 actgaagaaa gcgaaaccgg gctgcaaatt gccggataaa gtgatggact acctggagcg 2040 aagcggactt ataagcgtgg aggatgtttc acgatgacct ggcctgaagc attcacaacg 2100 gtaggaattg cgatggcggt ggcgctggtt gtgtattcga tttgccgctg gggataaaaa 2160 cgatttgcgg gaaaaggata gttaagtaga attgctgcgg gtgcttgagg ctatctgcct 2220 tgggcatgaa caccaaaggc agatagagaa aaacccaccc gactataaat caaagtgtat 2280 tacccccatt tgttggacga tgaaatgggt ttagttaact atgtcggtat cgacatgact 2340 aaaacaacct taaattgctc gattaataga caagtagttt tgaaagatta aatttatgcg 2400 atccggtatt ttcaagggat agcctttatg aggttatctt atggggttaa aacatcaaga 2460 acagttgtgt tataatacat agaaactaat aagagacgtt gcaactatat gaatgtaata 2520 gatttgtttt ctggcgttgg aggtctaagt cttggtgctg cacgtgctgg atttgatgtt 2580 aaaatggcag ttgaaattga tcaacatgct attaatactc acgcaattaa ttttccaaga 2640 agtttgcacg tccaagaaga tgtttcttta ctaaatgcag aaataattaa gggttttttt 2700 aaaaacgata tgcccataga tggtattatt ggcggtcctc cgtgccaagg atttagttca 2760 ataggcaagg ggaatcctga tgatagcagg aatcagcttt acatgcattt ctaccgttta 2820 gtatcagaat tacagccatt attctttttg gcagaaaatg ttccaggtat tatgcaagag 2880 aaatattctg gcattagaaa taaagcattt aatttggtta gcggtgatta tgatattctt 2940 gatcccatca aggtaaaagc atctgattat ggtgctccaa ctattcgaac tagatatttt 3000 tttatcggtg taaaaaaatc attgaagctt gatatttcag atgaagtatt tatgcctaaa 3060 atgattgatc cggttactgt aaaagatgct ttgtatggat taccagatat tatcgatgcc 3120 aattggcaat cagactctga gagttggcga acaattaaaa aagatcgaaa agggggattt 3180 tatgaaaaat tatgggggca gatccctcgg aatgttggtg atacagaatc gatcgctaag 3240 ttaaaaaata atatcatatc tggatgtacc ggaacattac atagcaaaat cgtccaagag 3300 cgttatgctt ccttatcttt tggggaaact gataaaattt caagatctac aagattagat 3360 ccaaatggtt tttgcccgac tttaagggcg ggaaccgcta gagataaagg aagctttcaa 3420 gccgtcaggc cgatccaccc ttatcatcca agagtgatta caccaagaga agctgctaga 3480 ttacaaggct tccctgattg gtttcgcttt catgtaacta aatggcatag tttcagacaa 3540 ataggaaata gcgtgtcacc aatagttgct gaatatatat taaaggggct gtacaattta 3600 ttaaataaaa gagtacagcc cgaatattta aaccataatt ctttggaagt tagggtataa 3660 cctatagtat ttataatagt tatcccgttc attttcgttt aaagagaact cttcagcggc 3720 tgcctgatat gcttctttat caggcagttt actatctaaa tttatctttt ctttaattgt 3780 tagtgttggt attgctattt cttgcacgtc ttcccaattt gttgaataaa attgccagtt 3840 agaaaggtcg catgccttag ataactctat atattcttgt tctgaggaga aaaaacctga 3900 tattgtcaac atggtatgac tgccatcatt atattgattt aaggataatg ggtaatactg 3960 aatcttatcc ttacgtcctg aaagaccacg ttctattgct gatctaaaag cgtttgtaat 4020 aattcgtatt aaaagagctt taatcttacg atctgaaaga tctgcatttg atatctgaag 4080 attaaaatca agatactttt tcccaagcaa tgattttaat gaattaataa aagcttcttt 4140 aaaaatatct aaactttctc caactctacg ttggtaataa gaactaggat ttatggggaa 4200 ggtgaccttc aaaatatcaa aagagcttac tttagtactt agtaagtgta tatcatctag 4260 atccgtttgt atttttttcg gggaggcata gtctaaccat gttattgatg gtttagaaaa 4320 actataatca agaataaagt catgagctga tattagctta caatcaatac aattataagg 4380 caaattatat ttttgtctga tgtgagtaga ctcttgttct tcgagagaaa tcatatcaga 4440 aagagcgata cgattatgca tgattctaaa atcttcaagc atcggaccac caaaacctat 4500 atatgtatat tcttgaatat ttagtctttt gcttaagagg tttaggcttt cgagaaaaat 4560 ctctctatca atagacttat tatgccttaa gtgataggga atgtattgtc cagacatcac 4620 ttcacctctt caatcaccgt atcaaagcat tgcatcccca catcagaagc gctagcatct 4680 tcatgtccaa agaaatattt agataaaatt ttaacatctt ctttctctct ggtgaagatt 4740 attcgtacag tagagctttt ttttactggg gtaggcagct taggtgtata tcgccactca 4800 tttttgtttc tattagggtt ggaccagtta ttttttttat cttctggagt tgattgtggg 4860 gtaatttcaa ataaagattg agcttcatgt gactgagctg acttaagtaa ttttttccct 4920 tcttcaagat gctcaccttt ccactgattg gtgaatcgaa taaaatgcat catcccttca 4980 atcattttat ttcgtacatc attgtacaat gtagaactaa gatcgacacc tcgtttcgtt 5040 gttgttattg gtaatttttc tgggttttta ctggtaaagc gaacaacccc agaaattgct 5100 ataaattggg tatgaaacct tggtacatta gcaaagcccc aacctgtgag atgtgtctta 5160 tcacaatata gaacaacgcg gtcattgcaa atgacagtcc atccagcatc atcagaactc 5220 cttttttcta aaacatcatc attgtcatct tctaaatttt tatagaagcc aacaactaaa 5280 tcgatatcaa catcgtctat tttagcttta tatatgtatg gttctatttt agaatgatca 5340 gttatgatgt taatcggatt atgttcaaca acaactccat ttaattctat tttaaatcct 5400 ttttgaataa taaatgacaa tgagtgtttt atctgtaaaa agagatcagt aagatatgtg 5460 ctctcattaa atttttgtgc cacattagaa tggagttttt ttatctctat agttgtgcct 5520 gttggatttt tgttatcata gtcactctcg tgcatcggta ttttccaacc atcaccatcg 5580 atccaatcag gtgttatatc tacagtgaat gcgccatcgg gattattcga ttgtattgag 5640 caatctctac ccattttaaa aatggctctt ttcataccaa taccatagac gccaacggtg 5700 ccttcatttt cttcttcttt ttgatggggt cgtcccattt taaaagcata ttctcggaag 5760 cttttaggga tacctccgca attgtcttct ataataaaga catctttatt aatcgtaagt 5820 ttcgcataaa atccttcata tggttttgaa gttttttttg tgtcttttat tgtacgtaaa 5880 gccccatcga cgcagttatc aagcagatca agtatggcat cgtttaagtc gatatctcga 5940 gttagcatac ttacaaaaaa tcttttacta ggactaaagt ctgctgttgg agtcgtgttc 6000 tcagtcataa tttactctct atgtgtttgg gaaaataaat accttaagtg caaattgttg 6060 attttaaacg cttcgcatgc gaagtcaacg atgttaagaa agaaagtgca tgtgatctaa 6120 cagtatgttt ttaaaaaaag attagcttta tgagaattca ggactgaatc ccgtgagagg 6180 aaaataacat atgttattgt tgcattgctg tgttgtttgg gatttgttgc accattctgg 6240 cgttggtata tctagttcgt tgttcatttt gttaattgta caacaggcag acaacagaga 6300 gcttttagcc tagttagctt acgaaattaa acaactaaga ttatcggcgg ggagtggtca 6360 ccgctactct ttggctagga gacttcaacg caaccgcaca caaccagctt cggcgggttt 6420 tgttttttcc tggcattctg gtttacaatt tgcgtgctag cttgaacaac tggcatctgc 6480 tgcactgcgc catcgagaga ttgagaaatg gcgcatatac aactggtcaa acaaacttct 6540 tctggtttac ttctcccggc gacgccggag agttgcgatt ttctgcatca aatcaaaata 6600 ggtgagtgga tacacgcaga ttttaagcgt gtgcgtaact acgcattcca caagcgtttt 6660 ttcaaactcc tgcaactggg attcgattac tggactccgg tcggtggggc gatcacgcct 6720 cgcgaacgag aactgctgtc tggtttcgtt gattacctgt gcgaatcagt tggtcgggaa 6780 cacacgccag ccctgagtga tgccgcagag caatacctta acaccgttgc gactcgtaga 6840 acccgggata cggcgttgct aaagtcgttt gaggctttcc gcgagtgggt aaccattcag 6900 gccggatttt acaccgagca tatttatccg gacggtagcc gtgggcgtcg ggcaaaatcc 6960 atcgcttttg cgaatatgga cgaagtcgag tttcagcagg tttataaatc tgtactgaat 7020 gtgctgtgga actggattct gttccgtaaa ttctcctctc aggaggaagt tgaaaatgtg 7080 gccgcacaac tactggagtt tgcgtaatgg tgaatttacg taaagcggct aaaggccaga 7140 tatgccagat cagaatccct ggctactgca atcacaatcc cgaaacctct gtgctggcgc 7200 attacaggct ggcgggaacg tgcggaacag cgataaagcc acacgatatg caggcagcga 7260 ttgcctgtaa ctcatgccac gatttaatcg acgggagagt aaaaaccagc gattacacca 7320 aagaagaatt gcgcctgatg catgcagaag gtgtttttcg cacacaagag atctggagaa 7380 aggacggtta tttatgattt acccaacgaa cacaggaaaa agcggagagc accttcgtct 7440 caccacgctg gaaagtgtct ggattcaggg gaaactacgt atgtgggggc gctggtcgta 7500 tattggcggc ggtaagacgg gaaatatgtt caaccagttg ctgacctcta aaaagctgac 7560 aaaaacggca attaacgagg cgctccggag gatgaaaaaa gcaggtctgg acaaacctaa 7620 acttgaggct tttttgcggg atatgatcaa cggcaagcaa aaaagctggc tggtgcattg 7680 taccgattca gaggcgttaa taatcgacag ggttattggt gaagtactgg caggttatcc 7740 cgggctgctc aatgttctga gtcagcgtta tgtggggcgg gggatgacta agcgcaaaat 7800 ggctgaactg ctgaatgatg cacatccgga atggagttta agaacctgtg aaagacgcat 7860 tgagcattgg ctaaaggtgg cagaatttat tttgtacaaa ccaatggtta tggcttttgg 7920 tatagagaaa aaagttattg ctttttgacg taaaaactgc ttcaattccg gtaagcttcg 7980 caaagctgta tcgcgaggcg aaccaaacgc atgaacttta ccagaacccg ccattgagcg 8040 ggttttttat tgcggaatta attacggacc gttattattc tgctcccggc cctttagctc 8100 agtggtgaga gcgagcgact cataatcgcc aggtcgctgg ttcaaatcca gcaagggcca 8160 ccatcacaaa ccgccattag cttatcagga agagcagacg acaccataac agggttgttg 8220 gtgcgggggc gggtccccga tggcggtcca ttatcggtat tctgcgttgt tagctcagcc 8280 ggacagagca attgccttct aagcaatcgg tcagtggttc gactccacta caacgcgcca 8340 cacttatttt ccaggctcgc ttcggcgggc cttttttgta tctgcgccac gcccggcgca 8400 tatcaaccac agagcctttc gggggtgagc ttacggagtg gtcagtgtga ctttctctgt 8460 gggcagatcg ctcccgggcg ttggctcacc cacccaaagg aacgtcacga tgtttggaat 8520 cttcaaaaag aaaacccgca gagcggcagc ggaaattaaa aagtttgaga aacgcgatct 8580 ggcacaggcg gtgattaacg ctgcatacct ggtggcctat gcagatggtg aatgcgaggc 8640 atccgagaaa gcgaagatcg aacaggtctt acgtaatcag cctgcgttgt ctgcgtttac 8700 ctcggaaatt aatgcgatta gcgcaactat tatcggtcag ctggatacca attttaaaat 8760 tggtcgtcgt gccgcgttac gcgagattga ggatgtgaaa cacgatacgc gtgaagcgga 8820 agatgtgctg gatgtggcgg tggccattgc ggaggcagac ggcgaaattg agccggaaga 8880 gcgcaaggtg ctggaagaga ttgccggtgt tctgggtctt cgtctggaga atcacctgtg 8940 acggtaaaac tgcgcctggc tgtggctgca ctcctgctgt ttctggtggt gatggtggat 9000 ttcaccagca gaatcatgtc ggtgctggcg gatggggtgc tggtctgcgg cattgtggta 9060 ttgctgtggc cggtgataaa aagaaacagc ctgcataatg cttgattttt ttgtttgctg 9120 tttattaaaa acacttctgc atggtgaatc cccctgtgcg gaggggcgat cagcaaccag 9180 gtatatggga taatcgcgga ttcaggtgct gatactgaat tcaccgggag gcacccggca 9240 ccatgcaaga aaaagaatgt gcatgcaaac atgcccctct ccggaggggc ttttttatgg 9300 gtaaaaaatg cccgaatggg ttcgggcaat agcatgagat actgatattg ttgtgttgtt 9360 atcgtgtgga ttttaaccag ggtttatcag gctgcgcaac tgcgtggcct tttttcattt 9420 cttgggctgt agtccccgag tgtcattcag gcttccggac tacagccagc ccactccata 9480 tctgatttaa tacactatcc cggccgggag gaataatgac atttaaacat tatgatgttg 9540 tcagggcggc gtcgccgtca gaccttgcgg aaaagctgac acacaaactg aaagagggct 9600 ggcagccata cggcggaccg gttgccatta cgccgtacac actgatgcag gcggtggcta 9660 ttgaaggaga gccacaggtc ggcccttcat ctgagccgga ttggtactac gtcatcgtac 9720 tggccgggca gtccaatgcc atggcttacg gtgaagggct tccgctgccg gattcatacg 9780 atgctccgga tccgcgcatt aaacagctgg cgcgccgcag tacagtgacg ccgggcgggg 9840 ctgcctgcag atataacgat attattccgg ctgaccactg tctgcatgat gtgcaggata 9900 tgagtacgct gaatcatccg agggctgacc tgagcaaagg gcagtacggc tgtgtcggcc 9960 agggtttaca tattgccaaa aaactgctcc cgtatatccc gaataacgcg gggatcctgc 1002 0 tggtaccatg ctgtcgtggt ggttcggcat ttacccaggg cgcggagggg acattcagcg 1008 0 agtccacggg ggccagtcag gattcggcac gctggggggt gggcaagccg ttatatcagg 1014 0 atctgatttc ccgcacaaaa gcggcattgc agaaaaatcc caaaaacgtt ctgctggccg 1020 0 tctgctggat gcagggtgag tttgacatga gcgccgccac ccacgcacag caacctgcgc 1026 0 tgtttacagc catgctgaca cagtttcgtg ctgacctctc cgtgtttaac gcgcagtgcc 1032 0 atggtggcag cgctgcagat gtgccgtgga tttgtggtga cacgacgtat tactggaaaa 1038 0 atacatacgc tacccaatac gacaccgtgt acggcgggta taaaaacagg gagagtgagg 1044 0 gcgtttattt tgtgcccttc atgacagacg gtaacggcgt caataccgcc actaacgcgc 1050 0 cggcagaaga tccggatatt ccggcatcag gatattacgg tgcggcatcg agaacgaatg 1056 0 gaaaccaggt atcatcaaac cgcccgacac atttcagttc atgggcgcgc aggagcatta 1062 0 ttccggatcg tctggcaacc gctattctga acgcagccgg gcgcacctcc gccttcatca 1068 0 gtggtaaggc accggaaatc aaaccctcgc ccggcggcaa cacgccatcg ggtccgtctg 1074 0 cagatacgtc cgttcgcaca atctccctgc tgccggcagc cggagaggct gctgcgcagg 1080 0 gctggagcat taaggatggc ggaattcagt tgtcagatgg tgtatttaag atcaccaggc 1086 0 agagcaataa aacctggtcc ctgacgcatc cggtggatga cgcaattacc ctgctgacac 1092 0 agggcggcag actgaactgt aagttccgcc tgtcaggcgc actgaccaac aatcagttcg 1098 0 ggctggggat ttatctgtat acggatgctc ccgttcctga tggtgtggcg atgacgggta 1104 0 ccggtaatcc gttcctgatg tcgtacttca ctcagaccac tgacggcaga gtgaatctga 1110 0 tgcatcacag gaaagccgga aacacgaagc tgggggagtt cggcgattac ggtaacgact 1116 0 ggcagacgct ggagctggtg ttcaccgccg gcagtgccac ggttactccg aaactgaatg 1122 0 gagtggctgg cccggcattc caggttataa aagacagtct gacactggga ctgaatgcgc 1128 0 tgacgctgac ggatgttaca aaaaatgcag cgtatggcgt tgagatagaa agtctggtgc 1134 0 tggagataaa tgcaccggca tcatcataaa aagtgagcca gtcaaatgga aggtatcgtt 1140 0 aaactcaccg gtagtgtcag tgggtcgtct gagacgcctg catgagttat cagagccatc 1146 0 agtagttaac tggtggcttt tttattgttg tcagcttccg gataacggga gacggggtat 1152 0 gtaccagatg gaaaaaatca caacaggtgt gtcatacacc acgtcagcgg tagggacggg 1158 0 atactggtta ctgcaactgc tggacaaagt ctctccgtcc cagtgggtgg caataggtgt 1164 0 actggggagt ctgctgtttg gcctgctgac gtatctgact aacctgtatt tcaaaatcag 1170 0 ggaggaccgc cgtaagacgg cgcggggaga ctaaagcgat gaagaaaaaa tacgaactgg 1176 0 ttgttaaaga gataaataat tacccggata agattgctgt tactgtggca cttgaaattg 1182 0 gcgggcatcc gtcgttgttg ttgccacatg tggcgattag tcttgaccgt actgaaggtg 1188 0 ccacgctgga gttttacgaa gctgaggcga aaaagcaggc gaagcagttt ttcatggatg 1194 0 ttgctgccgg gttatgtgaa ggggatggtc cgttaccgga aaagcgtccc gtaattttag 1200 0 aggcgcagga tgtgttgata acctacagag gaaaactacc gggaataatt acgggttctc 1206 0 tgaagactcc accgctggcc tgaagactta acatatccag ggatttgaaa tcgataaacc 1212 0 ctgataaata tccatgaacg caaaaatcag atacggcctg tcggctgccg ttctggcgct 1218 0 gattggtgca ggggcgtctg cgcctgaaat cctcgaccag tttctggatg aaaaggaagg 1224 0 taaccacacc acagcatacc gtgatggtgc gggtatctgg accatctgcc gtggagccac 1230 0 ccggggggat ggtaagcctg ttattcctgg catgaagctg tcgaaggaaa aatgcgaccg 1236 0 ggttaacgcc attgagcgtg ataaggcgct ggcatgggtg gagaaaaaca tcagagtgcc 1242 0 gctgaccgaa ccccagaaag cggggatcgc gtcattctgt ccgtacaaca ttggccccgg 1248 0 taagtgtttc ccgtcgacgt tttacagacg gattaatgca ggagatcgaa aaggtgcctg 1254 0 cgaagcgatt cgctggtgga ttaaggacgg tggcagggac tgccgtattc gctcaaataa 1260 0 ctgttacggt caggtatccc gtcgtgacca ggagagcgcg ctggcgtgct ggggaatcga 1266 0 cagataagca gaatattttg ctgaaaaatg aggtttgctt acatggacgg ataacacgaa 1272 0 atcctgcaaa ttggcaaaat gtaagtgaat aaagtcaaag cagttgttta acactcaggc 1278 0 accgtaatga tgcctttgtc atttctgcgc atctcacgcg catctcacaa cacagaacct 1284 0 ttcaggatga cccttgagga taccggtttg gctgtcggtg cctttctgtg ggctggattc 1290 0 ctgtgagaca aggttcatca ctaaaaggaa ataaccgatg aatatgatgg ccgtgccgtt 1296 0 tcacggcaac tctctttatg tagttaacca taatggcgaa ccatacgttc ccatgaaacc 1302 0 tgtcgttgcg gggatggggc tggcctggca atcacagttg gctaagttaa gacagcgttt 1308 0 tgcgtcaact ataacggaaa tcgttatggt tgctgaggat gggaaacaac gcaatatggt 1314 0 gtccatgcca cttcgaaaac ttgccggctg gctacaaacc attaatccca acaaagtaaa 1320 0 acccgaaatc cgcgataagg tcatccggta tcaggaagag tgcgacgatg ttctttacga 1326 0 gtactggacg aagggttttg tcgttaatcc ccgtaaaatg agcgtgatgg aagaactcaa 1332 0 ccaggcttgt gctgacatga aacgggataa aaacattgcc agtgtgtttg ctaccgggct 1338 0 gaatgagtgg aaacaggtta aagccgcgca tgtatcaaaa atccgtacgc tggtaaatga 1344 0 agcgaatatg ctgattgatt ttgtcctggc tgatacaggc aaagggaaaa taacaaaggc 1350 0 ggattgatgg ggtggctaat gatatcagat aaactcataa cgctggtgaa gagcctctgt 1356 0 gtacttgtcg gcatttcatt tttagtcatg ctggttgcca ttttcttttc caccgcctgg 1362 0 cgagtcctga cgttatcggg actggtgggg tgaaagagag atgaaccgtg ttctgtgtgt 1368 0 ggtgattatt gtcctggcgg ttggctatgg tgcgctgtgg ctggcaacaa accattaccg 1374 0 tgacaacgcg ctcacctaca aagcgcagcg cgataaaaaa gccagagagc tggaacaggc 1380 0 gaatgccacc attactgaca tgcaggtgcg ccagcgtgat gttgctgcgc tcgatgcaaa 1386 0 atactcgagg gagttagccg atgcgagagc tgaaaatgaa actctgcgtg ctgatgttgc 1392 0 cgctggtcgt aagcgcctgc ggatcaacgc cacctgctcc ggtaccgtgc gtgaagccac 1398 0 cggcacctcc ggcgtggata atgcaaccgg cccccgactg gcagacaccg ctgaacggga 1404 0 ttatttcatc ctcagagaac ggttgatgac aatgcagaag cagctggaag gggcacagga 1410 0 ctatatccgc actcagtgcc tgaactaagt tttgctgatg cgccgtatcg tcgccgtatt 1416 0 cctgcattaa cagagaccgc agcccgacag ggagactcct ctgcgagagt gtgcggggat 1422 0 aatcaaaaac gatacacacc ggggtttacc gcgtaaacgg agcgcggcgt tctcccctca 1428 0 tggtcgcccg tccggtgcga tggtggaaga aactggaatc tgttcaataa aaaaactgcc 1434 0 gtgttggagt cacagcagta atgtactgat tgggtagaag attattattg ttatgcttta 1440 0 tttttattct atatggctga ttatttcaat tcggaattaa tacagctaat gtctgtgagt 1446 0 ttttataaat tcagcaatat aaagaaatag ttatatgaac agccatcgca gagcatactg 1452 0 tgtatcattc ttttttatag tcaactgacg ggcatatttt atgtctgctg ccagctcccg 1458 0 gcggcaagat tcaatgaccc acgcagaaaa attttctgaa cctttctggt caagagcgat 1464 0 gttaatttgt tcaatcatct ggtttggaaa tcggatgttg cgggttgttg ttctgcgggg 1470 0 ccggtttttc gatgacattt tctttcctct ggtgacaagc tatatggcga ggattttaca 1476 0 tggctgtgct tcgtacgtta ccgggcagaa tcaaaactct gaacacccgg cggataaatg 1482 0 tcctgagggg ggaacagcgt cgtgtcagtg gcagtgcccg ggtttccctc aaacgtcgta 1488 0 tctggcggag ggatgccgga cactgttgtc tctgtagacg cgtggttgac ctttgtgaca 1494 0 gtgaactcga tcaccgcatt gcacttcagt tcggtggtgg taatgaggag acgaacctct 1500 0 ggaccctctg tactgaatgc catcgccaga agtcagcgag tgaagcggcg agtggtatgc 1506 0 ctgatccgac gttgcctgag cttcctgatg gcacgctcag ggccgacgga atcactggcc 1512 0 tgtgaccaga cccggggggg atcatccggc gaaaaaaaac gatcgccctg gacaccgcgc 1518 0 cccctctcac gcagagaaaa aattcccgtt tcagggcagt taacatgtta actggctgcc 1524 0 cgggcatttt tgcggttttt atctttatta ttcagtttgt tgtgcggaaa aaatgttaac 1530 0 aggctttttc agcaaatgtt aaccaggcag cagttaacat ttgcggcatg agacgccggg 1536 0 aaaaatgggc tgaaccatac ccggctgagt gcgttctgga cccgggagga ggctgtgctg 1542 0 acaacgcaaa aacgaaaatt tgcgctggcg ctcatgtccg ggaaaaacaa aacagcgtca 1548 0 gcccttgccg ccggttattc ggcgaagaca gccagggtta aaggctcgca gctggcaaaa 1554 0 gatccggagg tgcttgcgtt tatagcccgt aaacagtgcg agacggtgga ggtggatgag 1560 0 gttcctgttt atcggcagaa aaaatcagag ccggaggata aaccccgtcg ccgtgaggcg 1566 0 gctgcaatac cacagccgga cgaaacaaat ccggagatgc caccgcccgt ggtgatatct 1572 0 cctggtattg agtatatgga ggacggtctt cccgatccgg tgaaagcgat ggggcgtctt 1578 0 ctggtggaga acattaatac cgaccccagg ctggcgctgg atgcggctta taagctggcg 1584 0 cagttcacgc accacaaaaa aggggatgcc ggtaaaaaat cggcaaaagg tgacgcggcg 1590 0 aaaaaagcgg ctaaccgttt tgcggtgcca ccaccacccc gcctggtggt gaataatgat 1596 0 aatgagggca acggatgata cctgtgtgga gcacggcctg cccggactgg gcagagcgcc 1602 0 tgaaaaaggg gctgtcgatt attccggctc cgatttatcc ggagcaggcc gcacatgccc 1608 0 tggcgatttt taaacaactg cggattgtgg atgcaccggg cagcccgacg ttcggggagt 1614 0 cctgcgcaca gtgggtgttt gacctggtgg cggccctgtt tggctcctac gatgcgcaga 1620 0 ccggtgtacg ccatatcaag gaagttttta tccttatccc caagaaaaac agcaagtcca 1626 0 cgctggctgc cgggatcatg atgacggcgc tgttactgaa ctggcggcag gcggcgggct 1632 0 acaccattct ggccccgacc gtggaggtgg cggctaacgc cttcaaccct gccagggata 1638 0 tggtacgacg ggacgatgat ctggatgacc tctgtcaggt gcagacacat atccggacca 1644 0 tcacccacag ggtgacggac accaccctga aggtggtggc tgccgatccg aatacggtat 1650 0 ccggtatcaa gtccgtgggg acgctgattg atgaactgtg gttatttggc aagcagtaca 1656 0 aagcggagga catgttacgt gaagccatag gcggccttgc ctcccgcccg gaagggtttg 1662 0 tggtgtatac gaccacccag tcgaatgagc cgccagccgg ggtgttcaga cagaaactgc 1668 0 agtacgcccg ggatgtccgt gacggcaaaa ttcatgatcc gcactttctg ccggtgattt 1674 0 ttgagcatcc tcctgaaatg gtggaaagcg gggctcacct gctgatggaa aacctcgcca 1680 0 tggttaaccc gaatctcggt tattcggtgg atgaggcttt tctgtaccgg gagtaccgta 1686 0 aagcccggga ggctggtgag gaagcatttc gtggcttcat gtcaaaacat gccaatgtgg 1692 0 aaattggtct tgccctgcgt tctgaccgct gggcgggtgc ggatttctgg gagcagcagg 1698 0 gcaggcgcgt cagcctggac gatatcctgc agcgcgctga tgtggtgacg gtggggattg 1704 0 acggcggggg cctggatgat ctgctgggaa tgtacgtgat tggccgtgac agggaaaccc 1710 0 gcgaatggct gggctggggc catgcctggg cgcatgaaac cgcggtggtc cgacggaaga 1716 0 gcgaggcgtc ccggtttcag gatcttgttg cctgtggaga tatgaccatt gtccggcgtg 1722 0 tcggggatga cacggcggaa gtggcggaat atgtgcgtcg cattcatgag gctgagttac 1728 0 tggaccatat cggtattgac ccgtcagggg tggggcagat tctggattca ctggcggaag 1734 0 ccgggatccc cgacggaatt gtggtgggga taagccaggg ctggaaactg ggcggggcca 1740 0 ttaaaaccac cgagcgcaaa ctggctgaag gggtgctggt gcatggtgac cagcccctga 1746 0 tggcctggtg tgtcggcaat gcccgggtgg agcctaaagg taacgccatt cttatcacca 1752 0 aacaggccag tggacgggga aaaattgacc cgctgatggc gctgttcaat gcggtctccc 1758 0 tgatgtccct taacccggaa ccgaaaaaga aagaatatgc ggtttttttc atataaccct 1764 0 gttcacactg taaccatcat gaaccgctgc ggcggttttt ttattttcag gaggctgatg 1770 0 tgactcttaa acgggcctgt tccctgctga cggtgaaatc cttcagtgag gatgaacggg 1776 0 tgatcaccgg gattgcgtca acgccttctc cggatcggga tggtgacatc ctggagccgg 1782 0 agggcgcgga gtttggcagt gcgatcccgt ttctctggca gcatgaccat tcccgcccgg 1788 0 tggggcagtg tacggtgcgc cgggtcagcg aagggctgga aatcacggca acactggtga 1794 0 agcccgtacc ggatatgccg tcgcaactgg ctgcccggct ggatgaggtc tgggcggcca 1800 0 ttaagaccgg gctggtcagg gggctgtccg tgggcttccg tccccatgaa tacacctttc 1806 0 tggacggagg cggactgcat tttctgcgct gggaactgat ggaggtgtct gccgtcaccg 1812 0 tgcccgcgaa tgcggaatgc accatccgga ccattaaatc ttacgaccgc ccgttttctg 1818 0 ccgcgtccgg caaccggaaa ccggtggtga aaatcgcatc ttctgccggc gctgcggcac 1824 0 agtcaacaac cgtttttcat aaggaaaaga ccataatgaa tattggcgaa cagattaaaa 1830 0 gttttgaaaa caagcgtgca gcgctggcag cctcccttga ggaggtcatg accaaagccg 1836 0 cagaggaagg gcgcacgctg gatgtggagg aggaagagca ttacgacaac accgcagcgg 1842 0 aaatccgtca ggtggatgcg cacctgaagc gcctgcgtga actggaagcc ggtaaggccg 1848 0 ccacggcgca gccggtgaaa caggccggta acgggaatgt ggccgcggtg gcttctgcgc 1854 0 cggtgatccg tgtggagcag aaactggata aggggattgg cttcgcccgc tttgccaaat 1860 0 cgctggctgc ggctaaaggc gtccgatctg aagccctgga agtggcccgt cgtcagtatc 1866 0 cggatgacag tcgtctgcat catgtcctga aatcggcagt gggcgcgggg accaccacgg 1872 0 atccgcagtg ggcaggcagc ctgtctgaat atcaggaata cgcacaggac tttattgatt 1878 0 acctgcgtcc gcagaccatt atcgggcgat ttggtcaggg cgggatccct gcacttcgtc 1884 0 aggtgccatt caatatccgt gtgcacgccc aggtgtccgg cggtgctgcc ggctgggtgg 1890 0 gtgagggtaa ggcaaaaccc ctgacgaagt ttgattttga atccatcacc ttcagtcatg 1896 0 cgaaggtgtc ggccattgcg gtactgacgg aagaattgat ccgtttttcc agtccggctg 1902 0 ctgatgcact ggtccgtaat gcgctggcgg aagcggtggt ggcgcgtctg gatacagact 1908 0 ttgtggaccc gaaaaaagcc gcagtggcag atgtctcccc ggcgtccatc acccatgatg 1914 0 tgaagggcac ggcatcaacc ggtaacccgg atgcggatgc cgaggctgcg tttggacagt 1920 0 ttgtggcagc aaacctgcag cccaccggtg cggtctggct gatgtccagc accaatgccc 1926 0 tggcactgtc catgcgtaaa aatgcgctgg gtcagaagga atacccggac atgaccctgc 1932 0 tgggtggctc cttccagggg ctgccggtga ttgtctccca gtacgtgggt gaccagctgg 1938 0 tgctggtgaa tgccccggat atttatctgg cggatgacgg cggcgtggca gtggatatgt 1944 0 cccgcgaggc atcactggaa atgcagtctg agccgggcgg cgacagtacc acgccgtccc 1950 0 cggtggagct ggtttccatg ttccagacag gcagcgtggc catccgtgcg gagcgctgga 1956 0 tcaactggcg tcgtcgccgt actgcggcgg tggcggtgat caccggagtg aactacggca 1962 0 gtgcgtccgg cggctgagtc tgataaggag gacgggaggc gtgcgcctcc cgtaacaggt 1968 0 tatggcaaag atccgatatc tgcagggcac gcatgatgcc cgggccgggg atatccgtga 1974 0 tgtggcacag ccgtgtgcgg aggtgctggt tcgcctgggg aaggcggagt acatcacagc 1980 0 gcgacgtccg gcaggtcaga aaaagaaacg tgatgcggag catggcgaat gtggaacctt 1986 0 ttgcggcgaa cccgaaaaaa ccagaaatca ggacgtgacg taagagaagt gggctggcgg 1992 0 tccctgtttc aggcggtggc tgagcctttt gccggtgcct ggcagcaggg ggtgaaagcc 1998 0 gatccggaaa ccgttttgtc ctttcacgcg gtgttttcat gcatttcgct gatatcccag 2004 0 gatattgcca aaatgcggct tcgcctgatg cagactgatg tacagggaat acgccgggaa 2010 0 aagcggcagg gagatactgc ccgtctctgt cgtcgtccta atgcgcagca gaatcgcatc 2016 0 cagttttttg aactgtggct gaattccaaa ttgcgtcacg gcaatacggt ggtgctgaaa 2022 0 atccgcaccc cccgggggca gatcaaagaa ctgcgtattc tggactggaa ccgggttgaa 2028 0 cctctggtgg cggatgacgg cgaggtgttc taccgcatca cgccggaccg gaactgtggg 2034 0 atcacagagt cggtgacggt gcctgcccgg gaggtgatcc acgaccgttt taactgtttt 2040 0 tttcatccgc ttgtggggct gccgccggtg tatgccgcag gactggccgc catgcagggg 2046 0 catcatattc aggcaaattc gacgtatttt ttcagaaatg gcgggcgacc atcaggcgtg 2052 0 attgaggtcc ccggcagtat tacggaagaa aacgcgaaaa aactgaaggg gaactgggac 2058 0 agcggatata cgggcgaaaa tgccgggaag acggccatac tgagcaacgg ggcaaaatac 2064 0 agccccacga cgttttcacc ggtggatgcg cagacggtgg aacaactgaa aatgacggct 2070 0 gaaattgtct gttcggtgtt ccgtgtcccg gcctacaaga ttggcgttgg ccacccgcct 2076 0 tccagtgaca acgtggaggc gctggagcag cagtattatt cccagtgtct gcagacgctg 2082 0 attgagtcca ttgagctgtt actggatgag gcgctggaaa cgggggaaaa cgagagcacg 2088 0 gagtttgacg tcaccacgct gctgagaatg gacagcgaac ggcgcatgaa aacactgggt 2094 0 gaatcggtga aaaatacgct tctcacgccc aatgaggccc gtaaacgtga gaacctgccg 2100 0 ccccttgccg gcggtgatgc actgtatctt cagcagcaga actacagtct ggaggcgctg 2106 0 tcccgtcgtg atgcccgtga ggacccgttc gcgtcggccg ggaaaacagt ttcagcacaa 2112 0 ctgcctgacg gcgcatctga cggtaataag gcaatcagtg aaacagagca tgatgcagtg 2118 0 aaagcgatgt tcagggggat actgagaaaa tgacggaacg ggaactgtcc attattcgtg 2124 0 cactgggcga agaattctcc acggtgctgg cggatttaca gcgcacattt gaggggaaga 2130 0 tggccgcgca ggcacaagcg tttgaagaga aactggcttc cctgtcggcg gtattacaga 2136 0 agcatgtgac ggtggatgag gtacatccgg ttctgcaggc gatggtggat gacgctgtgg 2142 0 ggaccattcc ggtaccgcgt gatggtcgtg attatgatcc ggatgtactg cagcaggcgg 2148 0 tgaatgatgc ggttgcgaat attccggtac cggcggacgg caaaagtatc acccccgatg 2154 0 atgtgcgtcc gatgcttgag cagatggtga aagaggctgt aagccatatc cctgctccgc 2160 0 gtgacggtcg tgattatgat ccggaagtac tgaagcaggc ggtgaatgat gcggttgcga 2166 0 atattccggt accggcggac ggcaaaagta tcacccccga tgatgtgcgt ccgatgcttg 2172 0 agcagatggt gaaagaggct gtaagccata tccctgctcc gcgtgacggt cgtgattatg 2178 0 atccggaagt actgaagcag gcggtgaatg atgcggttgc gaatattccg gtaccggcgg 2184 0 acggcaaaag tattaccccc gatgatgtgc gtccgatgct tgaacagatg gtgaaagagg 2190 0 cggtaagcca tattcctgtt ccgcgtgatg gtcgtgacta tgatcccgat gttctgcaga 2196 0 aggctgttct ggatgcggtg agagccctgc cggctccgca ggacgggcgt gatgccacgg 2202 0 cactggaaat aatccccgcc attgacgatc aaaaatcctt tccccggggc acgtatgcca 2208 0 cacaccaggg cggactctgg cgggcgtatg aaaaaacgca cgggatgcgg ggatgggaat 2214 0 gcctggttga cggggtggcc gatattgacg tcagcatgac cggcgaacgg tcgttcactg 2220 0 tggtggtccg gcagagcagt ggccagcgta cggaaaaaac attttccctg ccggtgatgc 2226 0 tctaccgcgg tgtgttcaga gccggtgaaa cctaccaccc cggtgatacg gtgacgtggg 2232 0 ggggctcgct gtggcactgc aacagtatga ccggtgataa acccggagaa gctcattcat 2238 0 caggctggac cctggctgcc aaacgtggac gggatgcagg aggcggaaaa tgacggcatt 2244 0 actgacactg gaagagatca aggcacatct gcgtgtcgac catgacgcgg atgatgacat 2250 0 gctgatggac aaggttcgtc aggctaccgc cgtgctgctg gcctacattc agggcagccg 2256 0 ggataaggtg attcgtgagg acggtgagct gatcccgggc gaggcattaa cccggatgaa 2262 0 gggggctgcc atgcgactga ccgggatgct gtaccggaat ccggatcttg ctgagcggga 2268 0 agacctcgtg cagggggaac tgccgttttc tgtgtccgtg ctgatttacg atttgcgttg 2274 0 tccgacggtg ttatgaggag ggggaatggc aatatctgca ggtcgtctga cacagatgat 2280 0 aagtgttctg aacccggtgt taacccgtaa tgctgccgga gaaatgacgg aagaatgggt 2286 0 gtcatgcggg aaaattcatg cggatatccg tggcaggagc agccgggagc ggatgcagtc 2292 0 cggtgcggaa atggcgcagg cggaaatccg catctgggtg cgcggtcagt ccggccggga 2298 0 aatcacggca gcgtcacgac ttcatgtgct gagtggtcca tggcgtgacc ggatcctgaa 2304 0 cgttgtcggg ctgcccgtgc cggatgtgac cggcgggcgt ctggaaattc tctgtcggct 2310 0 gggaggggaa aaatgatcga aaccctgctg gatttttcgg ggctggagga catcagccgc 2316 0 gatttgcagc ttctgagtgg tgcggaaaat aaccgggtgc tgcgtgaggc aacccgtgcg 2322 0 ggtgcgaatg tgctgaaaga agaagtggtg tcacgggcac cggtacgcag gggaaaactg 2328 0 cgccgcaatg tggtggtcct ttcccggcgc tcccgcgatg gcgggatgga atccggtgtc 2334 0 catatccgtg gtgttaatcc ggacaccggt aacagcgata acaccatgaa ggcggataac 2340 0 ccgcgcaatg ctttctactg gcggtttgtg gaaatgggga ccgtgaatat gccaccgcac 2346 0 ccgtttgtgc gcccggcgtt tgatgtgcgc agtgaacagg cagctcaggt ggcgattgcg 2352 0 cggatgaacc gggccattga tgaggtactg agacgatgac ggaggcggat ttgtatcctt 2358 0 atctggcgca tcttgccggc gggcaggtgt acccgtatgt ggtccccctg ctggatggca 2364 0 ggccgtcggt ggcgcttccg tgggtggttt tcagcctgat ttcatcggtg tctgcggacg 2370 0 tgatgggcgg gcaggcggag tcctcagtgt cggtgcagat agacgtttat gccgggactg 2376 0 tgacgcaggc gcgtcagata cgtcaggacg cccgtgaagc cataatgctg ctggccccgg 2382 0 gatccgtcag tgaaatgcag gactatattc cggaaaaccg ctgttaccgt gcaaccctgg 2388 0 agtttcaggt cacggtgtga ctttttcttt tttttctaca aaacccatac cccgccgcgt 2394 0 gcgggttttt ttattatcag gaggcagaat gtctgctttg tatgaacgct cacagctgac 2400 0 gcaggtgatg atttcatctg ccccggcgac tgctgaaact atggataagg cggaatatct 2406 0 gcgcctggac tgcaccatca aggaagtcca gttcaccgcc ggtcagaaac aggatattga 2412 0 tgtgaccacg ctctgctcca cagagcagga gaacatcaac ggtctggggg cgtcgtccga 2418 0 gatttccatg tcgggtaatt tttatctgaa tcaggcccag aacgccctgc gtgatgccta 2424 0 tgacaatgac acggtgtatg cgtttaaggt gcagtttccg tccggtaagg gctttaagtt 2430 0 cctggcggaa gtgcgtcagc acacctggtc atccggtacc aacggcgtgg tggctgcaac 2436 0 gttttcactt cgcctgaagg gtaaaccggt gtcctatgtg gtaccgctgg cgtttgtgaa 2442 0 aaatccggag aagacactta ccgtgaatac cggtgcgctg ctgacaatgt cagtcagtgt 2448 0 caacggggga acgccgcctt ataaatacgc ctggaagaag gatggtcagc cggtcgaggg 2454 0 acagactact gacactttca gtaaagccaa tgcgcagtca ggtgataagg gggcttatac 2460 0 ctgcatggta atggattctg cagaacagcc gcagagcatt acctctgatg cgtgtacggt 2466 0 aacggttaat ggtgcgggcg gataaggctt atggcaaaag atctgaaaac actggcgctg 2472 0 gccagactgt cggggttccg tcataaaacg gtgaaggtgc cggaatggag aaatgtcagc 2478 0 gtggtgctgc gggagccttc ggcagaggcc tggtatctgt ggcaggaagt gctcaatggt 2484 0 gatggagagg atgacgatac cctgtcggtg gtggcgaaaa cccgccgtaa cctggaagcg 2490 0 gatgtgacgc tgttctgcga tgtcctgtgt gatacggatc tgcagcgggt gttcgctccg 2496 0 gacgaccgtg agcaggtgct ggccgtctat ggtccggtac atgcccggtt gctgcgtcag 2502 0 gcactggaac tgatcgctga tgcagagtcg gccagaaaaa agtagcccgc ccggaaattc 2508 0 gctttctgat gcgacttgcg ctccgtctgg ggcgcacctt atccgaactg cgccacagcc 2514 0 tgagtgcgag cgaggcgatg atgtggatgg agttcgacag ggtatccccg ctgggtgatg 2520 0 agcgcgggga tatccgtaat gcacagatcg tgaaagcggt tttcggggca caggggatga 2526 0 atgttgcact gaaggacgcc atgctctgct ggggcgagga tgaggataag ccggaggtgg 2532 0 atccgtttgc ggcgctggaa gacgcgctga gccttgcagc aatgtcataa ataatgatga 2538 0 aaacctgctg tggcaggttt tttttgcccg gagaaaggtg aatggcgacg ttacgtgaac 2544 0 tgattatcaa aatttcggca aattcgcagt cattccagtc ggagatccag cgggcgtccc 2550 0 gtatgggcag tgaatattac cggaccctgc agaatggcgg gcgtcaggcc gctgcggcag 2556 0 cccgggatca gcgacgtgcc ctggcagaac tgaacagcca gttgacggaa attcgcggtt 2562 0 ctgctgtcgg aatggctggc gcatttgccg gtgcctttgc caccggacac ctgatttcac 2568 0 tggctgatga gtggagttcc gtgaatgccc gtctgaaaca ggcgtcgcag tcatctgatg 2574 0 aattttcgtc atcacagaaa gtgctgatgg atatcagtca gcggacaggt accgcttttt 2580 0 cggataatgc ggccctgttt gcccgctcgg cagcctcaat gcgtgaatat ggttacagtg 2586 0 ctgatgatgt gctgaaggtg acggaggcca tttccacggg gctgaaaatc tccggtgcca 2592 0 gtacggctga ggcgggttcg gtgatcaccc agttcagcca ggcgctggca cagggtgtgt 2598 0 tgcgcggtga ggaatttaat tcggtcaatg aaagtggtga ccggatcgta cgtgcactgg 2604 0 ctgcgggtat gggcgtggcc cgtaaagatc tgaaggcgat ggcggacgat ggtcaactga 2610 0 cggcggataa agtcgttcct gcgttaatca gccagctgga ggtattgcgt gatgaatacg 2616 0 cggccatgcc ggaaacggtc tctgacggga tcacaaaggt ggaaaacgcc tttatggcct 2622 0 gggtgggtgg tgcgaatgag gccagcgggg tgacgaaaac gctctccggc gtgctgaacg 2628 0 gtgttgccgg acagattgat aatgtggcaa cagccgtggg ggcactggtt gccgtcgggg 2634 0 ttgcccggta ctttggcaat atggcctccg gagcgatgtc tgccacggca ggacttgtga 2640 0 cggctgcacg taatgaagtt gcactggcgg aagcacagtt caggggaacg cagattgcca 2646 0 cggcgcgggc aagagcagcc gtgtaccgtg ctcagcaggc cgtggcggca gcccgcggga 2652 0 cggagatgca gattgctgca gaagcccgtc tggcggccac acaggaacgc ctgaacagaa 2658 0 atattgctgc cagaagcgcc gcccagaatg cgctgaacag tacaacggcg gtgggctcac 2664 0 gtctgatgag cggtgcgctg gggctggttg gtggcgtacc cggactggtg atgctggggg 2670 0 ctgcagcatg gtacacgctg taccagaatc aggagcaggc cagggagtct gcgcgccagt 2676 0 atgcactgac gatagatgaa atcgcgcata aaacgccgtc aatgtctttg cctgaagcct 2682 0 cagataatga aggacgaaca cgggcggcgc tgacagagca gaaccggctg attgatgaac 2688 0 aggccagtcg ggtgaaatcc ctgcaggaaa aagcgcagtc cattcaggat gtgcttgccg 2694 0 ggctggaaga ccgtcgtgtg gcgttaattc gtcagcaggc ggcagagcag aataaggtgt 2700 0 accagtccat gctggttatg aacggtcagc atacggaatt caaccgtctg ctggggctgg 2706 0 gtaatgaact gcttcagcag cggcagggac tggtgaatgt gccgttacgg ctgccacagg 2712 0 ccactctgga tgataaacag cagagtgccc tgacaaaaac agagcgtgag ctggccctgt 2718 0 ccagactgaa aggggaagaa aaagagcgtg cccggctggg gtatgcggcg gatgaccttg 2724 0 gttttgtggg ggattcgtat caggaggcga gacagcgtta tatcagtaat gctctggaag 2730 0 cctggcgtaa taacgaggcg aacaaaccta aatcccgggg tggaaaatca gagacggaaa 2736 0 aagcggaaga cagtttttcc cggctgctga agcagcagaa ggcgcaactg gcactggccg 2742 0 gtcagaatac agagctggcg aagctgaagt accagactgc gcagggcgaa ctgaaaaccc 2748 0 tgacggagat acagaagcag gagctgctgc gcaatgcggc cctgattgac cagcaaaaaa 2754 0 tccgggaaca gttgcgatcc cgggaagaga cactgaagaa tgagaatgcg gctgcgcgtg 2760 0 cgtcgaatga tgctgaactg ctggggtacg ggcaggggga gcgagccaga gaacgcatgc 2766 0 gggagttgca gcagatccgc gacagcttcc gccagaagga tgcggacctt cagtctcagt 2772 0 atcagaccgg ggatatcagt gaggattttt acagacaggc tctggcacag aacgcgcagt 2778 0 atctgagtga acgccttaaa gaccaggaaa ctttttatgc cgaatcggat gcgcagcgtg 2784 0 cggactggca gaaagggctg caggagggat tcagtaactg ggtggataat gcgtccgatt 2790 0 acgcctcaca ggcagcacag cttgcgacgg agggtatctc agggatggtg aataacatca 2796 0 cggagatgct gaacggaaac aaagtggaat ggcgcagctg ggcctcatcc gtactgcagg 2802 0 aaatatcaaa agttcttatg aatgcggcca ttgtcaacgg aattaagacg gcggcaaacg 2808 0 gtatgtccgg tgcgggagga tttctcggca gcattggtga ctggctgggc ggagcggtgg 2814 0 ccaatgcaaa aggcggcgtg tatacctcgg caaacctgag tgcgtacagc aacagtattg 2820 0 tggatacgcc cacgtacttt gcctttgcaa aaggggccgg gctgatgggg gaggccggac 2826 0 ctgaagccat tatgcccctg acccgggcgg cggatggctc gctgggtgtg cgcgcggtgg 2832 0 gcagtatgaa cggcagtgcg ggtctggtgt attccccggt ctaccatatc gccattcaga 2838 0 atgacgggac taatggccag atagggccgg aggcggcagg cagtcttgtg cagctgattg 2844 0 accagcgggt gcaggcggtg atgctgtcca tgcgacgtga cggaggaatg ctgagtggct 2850 0 gagataaaaa cgctgcatct ggtcccgcgt gaagggatgc aggtgagtga gaagccgtcg 2856 0 gtggtgaggg tgcggtttgg tgacggttat gaacagcgcc gccccacagg gctgaatcct 2862 0 caactgaaga cgtttcaggc ggtgttccgg gtgacggatg agtcaacccg gcgctggctg 2868 0 gaagagtttt tatcgtggca tggtggttac cgtgcctttt tgtggcgacc gccgaaacat 2874 0 aaccggacgg tgagggtggt gtgccgggag tggagcgtca cggataacgc ccggtacagt 2880 0 gatttcagtt gtacgattga gcaggtggtg aactgatgca ggacattcat gaagaaagtc 2886 0 tgaacgagtc ggttaaatca gagcagtcac cgcgggtggt actctgggaa atcgacctga 2892 0 cggtgcaggg tggtgagcgg tattttttct gtaatgagct gaatgaaaaa ggggaggcgg 2898 0 tcacctggca ggggcggcaa tatcaggcat acccgattga cggcagcggt tttgagatga 2904 0 acgggaaggg cagcagtgcc cgcccgtcac tgacggtgtc caatctgttt ggccttgtca 2910 0 ccgggatggc ggaggacctg cagagtctgg tgggggccac ggtggtccgc cgccgggtgt 2916 0 atgcccgttt tctggatgcg gtgaatttcg ttgcgggcaa tccggaggcg gacccggagc 2922 0 aggagctgag tgaccgctgg gtggtggagc agatgtcgca gctgacagcc atgacggcct 2928 0 cgtttgtgct ggctacaccg accgagacgg atggggcgct gtttcccggt cgcatcatgc 2934 0 tggcgaatac ctgtatgtgg acctaccgct ctgatgagtg tggttacacg ggcggggctg 2940 0 tggcggatga gttcgacaac cccaccacgg atatccgtaa ggacagatgc agcaagtgca 2946 0 tgcgcgggtg tgagatgcgc ggcatggcgg ttaattttgg cggtttcctt tccatcaata 2952 0 aactttcgca gtaaatcctg ttttatgaca cagactgaat cagcgattct ggcgcatgcc 2958 0 cggcggtgtg cgccagcgga gtcgtgcggc ttcgtggtga gaacgccgga gggggagcgg 2964 0 tatatccctt gtgtgaatat ctctgcagag ccggaggcgt attttcgtat tgcaccggaa 2970 0 gactggctgc gggcagagat gcagggggag attgtggcac tggtccacag tcatcccggt 2976 0 ggtctgccct ggctgagcga ggccgaccgg cggctgcaga taaaaagtgc actgtcctgg 2982 0 tggctggtct gccgggggga aattcataaa ttccgctgtg tgccacatct gacaggacgg 2988 0 cgctttgagc acggggtgac ggactgttac acgctgttcc gggatgccta ccatctggcg 2994 0 ggaattgata tgccggattt tgagcgtgag gatgactggt ggcgcaacgg tcagaacctg 3000 0 tacctggaca atatggaggc gactggtttt tacaggattt ccctgccttc cgcacagcct 3006 0 ggcgatattc tgctgtgctg ctttggtgct tcggtaccga accatgccgc catttactgc 3012 0 ggcaacggtg agctgcttca ccatctgcct gaacaactga gtaaacggga gaggtattcc 3018 0 gaaaaatggc aacgacgaac gcattcagcc tggcgtcacc gccactggca cgcatctgcc 3024 0 ttcacgggga tttacaacga tttggccgcc gcctcagcct gtatgtgaac acggcagcgg 3030 0 aagccatccg ggcgctgtcg ttacaggtgc ccggattccg ccgtcagatg aacgaaggct 3036 0 ggtaccagat acgtattgcc ggtgatgaca cggcaccgga ggcggtgtac gcccgtcttc 3042 0 acgaacagct gggtgaggga acggtcatcc acattgtgcc gcgactggcc ggggccggaa 3048 0 agggtggact gcagattgtg ctgggggcgg cagccatcgt gggctctttc ttcacggccg 3054 0 gagcatcgat ggcagcctgg ggtgcagcgc tgagtgccgg cggtttttct gccaccacga 3060 0 tgctgttttc actgggtgcc agcatgatac tgggtggtgt ggcacagatg ctggccccga 3066 0 agccaaaaac accggaatac agggcaacgg ataacggtaa acagaacacg tacttttcgt 3072 0 cgctggacaa catgattgcc cagggtaacc cgatgccggt gccttacggg gaaatgctgg 3078 0 ttggctcccg ccgtatatcc caggacatca gtacccgtga tgaaggcggg ggcggaaagg 3084 0 tcgtggttat cgggcggcag gcataaaagc gaaaaaatcc cgcagtgctc acggacagga 3090 0 actgcgggag cgttacgaag attgagtgta aggaattatt cttatgtcac gacaaaaaca 3096 0 ttaactcaga gagggaggat gtgccgttct tttcagggag aaaggattta tcgtcctgag 3102 0 gaataaaggt aaggggcccg ccccttacct gactgattat tgaatgatgc cgcaggccat 3108 0 tctcgcacca ccaccgccca ggggctccgg atggtcatga tggttatcac cgccagcatg 3114 0 aagcatgaga gaacgccctt taatctcttt taatgagttc agtctcgggg ccaggaccgg 3120 0 gtagttcgct tttccgtcat gcgtcacgaa cagcgcaggg aggtcgccca ggtgtccatc 3126 0 cggagaccag gggccaagat gtttgccggt gtttttcggg tcaaagtgac cgccagccga 3132 0 taatgctgcg accggttttc cgtctttcag tgccggggcg caatttcctt tttcgtgcac 3138 0 atgaaaacca tgaatgcctt cagacagaga gtgaagggct ggtgtgaaca gcagaccgta 3144 0 gggggtctcc tgaatggtta tttttccaat gctgacttct tttccgtcag cactgacaag 3150 0 gttcattggg acttcctgtt ctgctgcgta tccgcatgat gctgctgtca gcatggcaat 3156 0 ggcagcaatg attttacatt tcataaaacc ctcattaatt ccgttaacag actgagcttg 3162 0 ctggttacag ggtaacaaac agcgttctga tgatatcgcg caatagctgt gcaatatcct 3168 0 atcactgcga ttaataatac caattgagag gaacattatg ggcaaaggtg gcggcagggc 3174 0 gcacacgcct cgagaggcga aggataatct caaatccacg cagatgatga gtgtgattga 3180 0 tgcgattggt gagggaccga tagaaggccc ggtgaagggg ctgcagagta tcctggtgaa 3186 0 caaaaccccg ctgacggaca cggacggtaa tcccgtgata cacggtgtga ctgcggtctg 3192 0 gcgtgccggg gagcaggagc agacaccacc ggaaggcttt gagtcctccg gagctgaaac 3198 0 cggactgggc gtggaagtga cgaaggcaaa gccggtgacg cgcaccatta cgtccgcgaa 3204 0 cattgaccgc ctgcgggtta ccttcggggt gcagtcactg gtggagacca cctcaaaggg 3210 0 tgaccgtaac ccgacgtctg tccgcctgct gattcagctt gagcgtggtg gtaaatggat 3216 0 gacggaaaag gatgtcacca ttaacggcaa gaccacctcg cagttcctgg cgtcggtgat 3222 0 tctggataat ctgccgcccc ggccctttaa catccggatg gtcagggaga cggcggacag 3228 0 caccacggac cagctgcaga ataagacgct ctggtcgtca tacaccgaaa tcatcgatgt 3234 0 gaaacagtgc tacccgaaca cggcgattgt ggggctgcag gtggatgcgg agcagtttgg 3240 0 cggtcagcag atgacggtga actaccatat ccgcggtcgc attattcagg tgccgtcaaa 3246 0 ctatgacccg gaaaaacgca cgtacagcgg catctgggac ggcagcctga aaccggcata 3252 0 cagcaacaac ccggcctggt gtctgtggga catgctgact cacccgcgct acgggatggg 3258 0 aaaacgtctg ggggcggcgg atgtggacaa atgggcgctg tatgccattg cgcagtactg 3264 0 cgaccagacg gtgccggatg gtttcggggg cacagagccg cggatgacct ttaatgcata 3270 0 cctgtcacaa cagcgtaagg cgtgggacgt cctcagtgat ttctgctcgg cgatgcgctg 3276 0 tatgccggta tggaacggcc agacgctgac gttcgttcag gaccgcccgt cggatgtggt 3282 0 gtggccgtac accaacagcg atgtggtggt ggatgataac ggcgtggggt ttcgctacag 3288 0 cttcagcgcc ctgaaggacc gccacacggc ggtggaggtg aattacaccg acccgcagaa 3294 0 cggctggcag acctccacgg aactggtgga agacccggaa gccatactgc gctacgggcg 3300 0 caacctgctg aagatggatg cgttcggctg caccagtcgc ggtcaggccc accgtgccgg 3306 0 gctgtgggtg ataaagaccg gactgctgga aacgcagacg gtggatttca cgctcgggtc 3312 0 acaggggctg cgtcacacac ccggtgacat tattgaaatc tgtgataacg actatgccgg 3318 0 gaccatgacc ggcggacgta tcctgtccat cgatgccgcc agccgcaccc tgacactgga 3324 0 ccgtgaggtg accctgccgg agacaggtgc cgccacggtg aacctgatta acggcagcgg 3330 0 taagccggtg agcgtggcca tcactgcaca ccccgcgccg gaccggatac aggtcagcac 3336 0 cctgcctgat ggtgtggaga catacggtgt atggggactc tccctgccgt cactgcgtcg 3342 0 tcgcctgttc cgctgtgtct ccatccggga aaacacggac ggcacctttg ccatcacggc 3348 0 ggtgcagcac gtgccggaaa aagaagccat cgtggataac ggggcgcact ttgacggcga 3354 0 ccagagcggc acggtgaatg gtgtcacgcc gccagcggtg cagcacctga ccgccgaagt 3360 0 caccgcagac agcggggaat atcaggtgct ggcgcgctgg gacacgccga aggtggtgaa 3366 0 gggcgtgagc ttcctgcttc gcctgaccgt ggcagcggat gacggcagtg agcggctggt 3372 0 cagcacggcc aggacgacag aaaccacata ccgcttcacg caactggcgc cggggaacta 3378 0 caggttgaca gtccgggcgg taaatgcgtg gggacagcag ggcgatccgg catcggtatc 3384 0 gttccggatt gccgcaccgg cagcgccgtc tcggattgag ctgacaccgg gctattttca 3390 0 gataaccgcc acgccgcatc ttgcggttta tgatccgacg gtacagtttg agttctggtt 3396 0 ctcggaaaag cggattgctg atatcaggca ggttgaaacc acagcccgct atcttggcac 3402 0 ggcgctgtac tggatagctg ccagtatcaa tatcaaaccg ggccatgatt attactttta 3408 0 tatccgcagt gtgaacaccg ttggcaaatc ggcatttgta gaggctgtcg gtcagccgag 3414 0 tgatgatgca tcaggctatc tggatttttt caaaggcgag atagggaaaa cccatctggc 3420 0 tcaggagctg tggacgcaga ttgataacgg tcagcttgcg cctgacctga ctgaaatcag 3426 0 gacgtccata acggatgtca gcaatgaaat aacacagacc gtcaataaga aactggaaga 3432 0 ccagagtgca gcgatccagc agatacagaa ggttcaggtt gatacaaata ataacctgaa 3438 0 cagcatgtgg gcagtgaagc tgcagcagat gcaggacgga cgcctttata ttgcgggtat 3444 0 cggtgccggt attgagaaca cccccgacgg catgcagagt caggtgctgc tggcagcaga 3450 0 caggattgcg atgattaatc ctgcgaatgg caacacaaag ccgatgtttg ttggtcaggg 3456 0 cgatcagata ttcatgaatg aagtgttcct gaaatatctg acggctccca ccattaccag 3462 0 cggcggtaat cctccggcat tttccctgac accagacggg cgactgacgg cgaaaaatgc 3468 0 ggatatcagt ggcagtgtga atgcgaactc aggagcgctc aacaatgtca cgattaacca 3474 0 gaactgtacg attaagggca tgctggaggc gacccaggtc agaggggatt tcgttaaagc 3480 0 tgtatcaaaa gccttcccga aaaaagtcgg tacgtggggt aacacggaaa caccaaacgg 3486 0 tacggttaca gtcaccatca gcgatgatca taactttgac cgccagatta ttattccgcc 3492 0 cattattttt aacggtatag cgtatgacga tccggggagc ggaaataacc caggaggcac 3498 0 gcgatacacg gggtatggtt ttgaagttcg caaaaacggc gtattaatcg catccagaga 3504 0 aactaaaggg gccattcccg gtagttacag tgcagttatt gatatgccta gtggtggtgg 3510 0 tagcgtcact ctggagttta agattttcca gaaaggcaat cagggggcag gcaatatcac 3516 0 cgactgtacg gtgattgtga ccaaaaaagc tgcttccggc atcagtattc gttgaaatat 3522 0 ttataacccc aataaagggc gtcaggaatg acgccttttt tattgcagaa aagcgagagg 3528 0 taattatgcg taaactttat gccgccattt tgtccgcagc catttgtctg accgtatccg 3534 0 gtgcgcctgc atgggcgtct gagcagcagg ccacgctgag cgcggggtat cttcatgtct 3540 0 cgacgaacgc tcccggtagc gataatctta acgggattaa cgtgaaatac cgttatgaat 3546 0 tcacggacac gctggggctg gtgacgtcat tcagctatgc aggagacagg aatcgccaga 3552 0 ttacccgtta cagcgatacc cgctggcatg aagattccgt gcgtaaccgc tggttcagcg 3558 0 taatggcggg gccgtctgtg cgcgtgaatg aatggttcag cgcgtatgcg atggcgggag 3564 0 tggcttacag ccgtgtgtcg actttctccg gggattatct ccgcgtaact gacaacaagg 3570 0 ggaaaacgca cgatgtgctg accggaagtg atgacggtcg ccacagcaac acgtctctgg 3576 0 cgtggggggc tggcgtgcag tttaacccga ccgaatccgt ggccattgat attgcttatg 3582 0 aaggctccgg cagtggcgac tggcgcactg acggtttcat cgtgggtgtc ggttataagt 3588 0 tctgattagc caggtaacac agtgttatga cagcccgccg gttcaggcgg gcttttttgt 3594 0 ggggtgaata tggcagtaaa gatttcaggt gtactgaaag acggcacagg aaaaccggta 3600 0 gagaactgca ccattcaact gaaagccaga cggaccagca gcacggtggt ggtgaacacg 3606 0 gtggcctctg aaaatccgga tgaagccggt cgttacagca tggacgttga gtacggtcag 3612 0 tacagcgtca ttctgttggt ggaaggattc ccgccgtcac atgccgggac catcaccgtg 3618 0 tatgaagatt ctcaacccgg tacgctgaat gattttctcg gtgccatgtc ggaggatgac 3624 0 gtccggccgg aggcactgcg tcgttttgaa ctgatggtgg aagaagcggc gcgtcacgct 3630 0 gaggaggcga agaagaatgc cggagaggcg gagacgtccg cgaggaatgc cggcatatca 3636 0 gccagtcagg cagaagagag cgctgcaaat gctgacactt cagcagggga tgcatcggag 3642 0 tcagcccggc aggcggcaga aagtgcagcc gctgcaaagc agtcagagga tgcgtcctcg 3648 0 tcctcggctt ctgcggccgc tcaaaaagcc agtgagtcat cacaaagtgc agcagaagct 3654 0 gaattgtcaa gaaagacggc agaaagtgca gccggtaatg cagccaggga tgcaacgacc 3660 0 gcaacagaaa aagcccggga gtcagcagaa agcgcacagt cagcggaaca aagcaggata 3666 0 gcggcggaag aggccgtaaa ccgaatcccc accgtggtgg gacctcccgg gccaaagggg 3672 0 gaacaggggc ccgcgggtcc tcaggggccg aagggtgata agggagagcg cggtgacacc 3678 0 ggccctgtcg gggcaaccgg cgaacgggga ccggcaggtg atgctggtcc ggcaggcccg 3684 0 caggggccga aaggtgacag gggagagcgg ggagagaccg gtctgacggg aaatgcaggt 3690 0 ccacagggtc caaagggaga taccggtgcg gcaggcccgg caggcccaca gggaccgaaa 3696 0 ggagaaacag gtgcggctgg cccggtgggg gcaaccggac ctcagggacc gaagggcgac 3702 0 ccgggggaga cacaaatccg ttttcgtctg gggccgggaa acattattga gacaaacagc 3708 0 aatggctggt tcccggatac agatggcgca ctcatcaccg gactgacctt tcttgccccc 3714 0 aaagatgcca cacgggttca gggttttttt cagcatttgc aggtcaggtt tggtgacggg 3720 0 ccgtggcagg atgttaaggg gctggatgaa gtgggcagtg atacaggcag aacaggagaa 3726 0 tgacatgaat attttgagaa agcttatgga gcgtctgtgt ggttgcggaa agcatgatga 3732 0 ctgtgaacac gggcagtcgc ttacagtaca actgcgactg gggccggcag acatcctgga 3738 0 gtcagatgag aatggcatta ttccggagca ggacagggta atcacacagg tggtgatact 3744 0 ggatgcggat aaaaagcaga tacagtgcat ggtaagaccg ctgcaaatcc tacgtgctga 3750 0 cgggaggtgg gaaaatattg gcgggatgaa atagccgacg ggttcacaaa aaccggagtc 3756 0 ctgctctggt ttttgttgtc acgtatgggg gatgtttgtt acagctattt aagtctggag 3762 0 ttcaaattaa aatagggagc tttgttatgc cattaacctc agatattaga tcacattcat 3768 0 ttaatcttgg ggtggaggtt gttcgtgccc gaattgtagc caatgggcgc ggagatatta 3774 0 cagtcggtgg tgaaactgtc agtattgtgt atgattctac taatgggcgc ttttcatcca 3780 0 gtggcggtaa tggcggattg ctttctgagt tattgctttt gggatttaat agtggtcctc 3786 0 gagcccttgg tgagagaatg ctaagtatgc tttcggactc aggtgaagca caatcgcaag 3792 0 agagtattca gaacaaaata tctcaatgta agttttctgt ttgtccagag agacttcagt 3798 0 gcccgcttga ggctattcaa tgtccaatta cactggagca gcctgaaaaa ggtatttttg 3804 0 tgaagaattc agatggttca gatgtatgta ctttatttga tgccgctgca ttttctcgtt 3810 0 tggttggtga aggcttaccc cacccactga cccgggaacc aataacggca tcaataattg 3816 0 taaaacatga agaatgcatt tatgacgata ccagaggaaa cttcgttata aagggtaatt 3822 0 gaaatgaaca ttacccttta ttttatttaa tgaaacatcc tgcaaactga tatgaattac 3828 0 tgaatgaggt ttttatgcct gttaccacct taagtatccc aagtatatct caattatctc 3834 0 ctgcaggagt acagtctttg caggatgctg ccagacttga aagtggaata agaatatcca 3840 0 ttggtagtgg ccaatattct gttcactatg tccagctact ggatggattt tcagttgaac 3846 0 cggtgagagg aggcttactg gataggctat tggggcgtga gcatcgaatg gagagaaggg 3852 0 ctgtggctct ggaaaggcaa ttaaatggag gtgtcgattt tttaagtagt gttaataact 3858 0 attttcagag tgtcatggca gaacacagag aaaataaaac aagtaataaa atattaatgg 3864 0 aaaaaataaa ttcttgttta tttagacctg attctaatca cttttcttgc ccggagtcat 3870 0 ttttgacatg cccgataacg ctggacacac ctgagactgg ggtgttcatg agaaactcac 3876 0 gaggtgctga gatatgctct ctatatgata aggacgcgtt agtgcaactt gttgaaactg 3882 0 gtggagctca tcctctgagt cgagaaccta taacagaatc aatgattatg agaaaagatg 3888 0 aatgtcactt tgatacaaaa agagaagctt tttgttgtaa gtgataatta atgatataaa 3894 0 tgtagtttta tgtactttta ttttttacta aagcaaaatt aagttattaa aatggaggga 3900 0 gaggaatgcc tgtagattta acgccttata ttttacctgg ggttagtttt ttgtctgaca 3906 0 ttcctcaaga aaccttgtct gagatacgta atcagactat tcgtggagaa gctcaaataa 3912 0 gactgggtga gttgatggtg tcaatacgac ctatgcaggt aaatggatat tttatgggaa 3918 0 gtcttaacca ggatggttta tcgaatgata atatccagat tggccttcaa tatatagaac 3924 0 atattgaacg tacacttaat catggtagtt tgacaagccg tgaagttaca gtactgcgtg 3930 0 aaattgagat gctcgaaaat atggatttgc tttctaacta ccagttagag gagttgttag 3936 0 ataaaattga agtatgtgca tttaatgtgg agcatgcaca attgcaagtg ccagagagct 3942 0 tacgaacatg ccctgttaca ttatgtgaac cagaagatgg ggtatttatg aggaattcaa 3948 0 tgaattcaaa tgtttgtatg ttgtatgata aaatggcatt aatacatctt gttaaaacaa 3954 0 gggcggctca tcctttgagc agggaatcaa tcgcagtttc aatgattgta ggaagagata 3960 0 attgtgcttt tgaccctgac agaggtaact tcgttttaaa aaattaaggt agcaatggcg 3966 0 ggttaacttt tcgtaaaatg aaattaattc tcggtacggc atgtaaaacg cggcacctcg 3972 0 tatgcaagaa cgtgccgcgg ttggctggta agcttttcga tagtgcgagt atctaatgat 3978 0 ttccagccgg aactgattct attggaaaga aatcatgggc gcca 3982 4 <210> 877 <211> 79 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9..245) <400> 877 Met Val Arg Pro Phe Leu Ser Pro Gln Val Leu Arg Tyr Gln Tyr Arg 1 5 10 15 Arg Leu Gln His Arg Lys Ile Leu Lys Gln Lys Arg Trp Arg Thr Leu 20 25 30 Cys Ser Arg Cys His Arg Leu Leu Lys Arg Glu Arg Met Thr Trp Phe 35 40 45 Tyr His Arg Cys Ile Trp Gln Thr Ala Asn Cys Val Gly Arg Lys Ile 50 55 60 Met Ser Arg Ser Gly Ser Glu Ser Ala Pro Arg Cys Gly Ser * 65 70 75 <210> 878 <211> 141 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(326..748) <400> 878 Met Ala Lys Val Phe Thr Pro Glu Glu Arg Glu Lys Ile Lys Gly Gln 1 5 10 15 Val Val Glu Leu Val Arg Leu Ser Gly Arg Glu Thr Leu Arg Ala Leu 20 25 30 Glu Ala Lys Thr Gly Ala Ser Arg Tyr Tyr Ile Ser Thr Leu Ala Arg 35 40 45 Glu Leu Val Ala Ser Gly Asp Val Tyr Asn Ser Gly Tyr Gly Leu Phe 50 55 60 Pro Ser Glu Gln Ala Arg Lys Asp Trp Gln Asn Ala Arg Lys Lys Leu 65 70 75 80 Ser Arg Ala Lys Val Lys Lys Pro Val Val Val Asp Pro Asp Leu Ile 85 90 95 Trp Ser Leu Pro Asp Gly Glu Ile Arg Arg Tyr Asp Arg Arg Leu Asn 100 105 110 Ile Ile Cys Ser Glu Cys Arg Lys Ser Glu Ala Met Gln Arg Val Leu 115 120 125 Ala Phe Tyr Gln Gly Asn Phe Gln Lys Val Leu Leu * 130 135 140 <210> 879 <211> 71 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(854..1066) <400> 879 Met Leu Asn Thr Gln Lys Ala Ile Asn Ala Glu Lys Tyr Asn Glu Trp 1 5 10 15 Ala Arg Lys Phe Ser Glu Gln Ile Phe Lys Ile Thr Gly Asp Glu Asn 20 25 30 Ala Ala Lys Asn Glu Leu Glu Pro Trp Thr Pro Glu Gly Ala Asp Pro 35 40 45 Asn Tyr Cys Trp Arg Glu Val Asp Pro Val Asp Ala Ala Asn Glu Ala 50 55 60 Met Ser Tyr His Asn Asp * 65 70 <210> 880 <211> 88 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1318..1581) <400> 880 Met Ala Thr Leu Thr Lys Lys Glu Arg Ala Trp Leu Asn Glu Leu Gln 1 5 10 15 Glu Val Leu Asp Arg Cys Pro Ser Pro Lys Lys Ile Gly Phe Tyr Thr 20 25 30 Ile Gly Asp Lys Ser Ile Tyr Leu Tyr Asp Leu Arg Arg Met Asp Glu 35 40 45 Ile Met Glu Ala Leu Asp Asn Arg Ser Ser Met Asp Trp Cys Val Ala 50 55 60 Val His Asp Met Asn Ala Gly Phe Asp Glu Lys Ile Leu Phe Pro Ser 65 70 75 80 Ser Val Glu Ser Thr Ala Gly * 85 <210> 881 <211> 54 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1592..1753) <400> 881 Met Thr Thr Ile Thr Lys Glu Arg Ile Glu Leu Phe Ile Lys Asn Pro 1 5 10 15 Val Glu Asn Gly Leu Thr Arg Gly Glu Gln Met Glu Leu Ala Arg Ile 20 25 30 Ala Leu Ala Ser Leu Glu Ala Glu Pro Val Gly Asp Phe Tyr Glu Tyr 35 40 45 Lys Pro Asp Asp Trp * 50 <210> 882 <211> 82 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1832..2077) <400> 882 Met Asp Leu Leu Thr Cys His Leu Asp Gly Val Thr Glu Thr Tyr Ala 1 5 10 15 Glu Gly Trp Asn Ala Cys Arg Ala Ala Leu Leu Gln Gly Lys Gly Glu 20 25 30 Pro Gly Lys Gln Val Arg Glu Leu Thr Met Leu Val Lys Gln Leu Val 35 40 45 Ser Gln Leu Lys Lys Ala Lys Pro Gly Cys Lys Leu Pro Asp Lys Val 50 55 60 Met Asp Tyr Leu Glu Arg Ser Gly Leu Ile Ser Val Glu Asp Val Ser 65 70 75 80 Arg * <210> 883 <211> 384 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2509..3660) <400> 883 Met Asn Val Ile Asp Leu Phe Ser Gly Val Gly Gly Leu Ser Leu Gly 1 5 10 15 Ala Ala Arg Ala Gly Phe Asp Val Lys Met Ala Val Glu Ile Asp Gln 20 25 30 His Ala Ile Asn Thr His Ala Ile Asn Phe Pro Arg Ser Leu His Val 35 40 45 Gln Glu Asp Val Ser Leu Leu Asn Ala Glu Ile Ile Lys Gly Phe Phe 50 55 60 Lys Asn Asp Met Pro Ile Asp Gly Ile Ile Gly Gly Pro Pro Cys Gln 65 70 75 80 Gly Phe Ser Ser Ile Gly Lys Gly Asn Pro Asp Asp Ser Arg Asn Gln 85 90 95 Leu Tyr Met His Phe Tyr Arg Leu Val Ser Glu Leu Gln Pro Leu Phe 100 105 110 Phe Leu Ala Glu Asn Val Pro Gly Ile Met Gln Glu Lys Tyr Ser Gly 115 120 125 Ile Arg Asn Lys Ala Phe Asn Leu Val Ser Gly Asp Tyr Asp Ile Leu 130 135 140 Asp Pro Ile Lys Val Lys Ala Ser Asp Tyr Gly Ala Pro Thr Ile Arg 145 150 155 160 Thr Arg Tyr Phe Phe Ile Gly Val Lys Lys Ser Leu Lys Leu Asp Ile 165 170 175 Ser Asp Glu Val Phe Met Pro Lys Met Ile Asp Pro Val Thr Val Lys 180 185 190 Asp Ala Leu Tyr Gly Leu Pro Asp Ile Ile Asp Ala Asn Trp Gln Ser 195 200 205 Asp Ser Glu Ser Trp Arg Thr Ile Lys Lys Asp Arg Lys Gly Gly Phe 210 215 220 Tyr Glu Lys Leu Trp Gly Gln Ile Pro Arg Asn Val Gly Asp Thr Glu 225 230 235 240 Ser Ile Ala Lys Leu Lys Asn Asn Ile Ile Ser Gly Cys Thr Gly Thr 245 250 255 Leu His Ser Lys Ile Val Gln Glu Arg Tyr Ala Ser Leu Ser Phe Gly 260 265 270 Glu Thr Asp Lys Ile Ser Arg Ser Thr Arg Leu Asp Pro Asn Gly Phe 275 280 285 Cys Pro Thr Leu Arg Ala Gly Thr Ala Arg Asp Lys Gly Ser Phe Gln 290 295 300 Ala Val Arg Pro Ile His Pro Tyr His Pro Arg Val Ile Thr Pro Arg 305 310 315 320 Glu Ala Ala Arg Leu Gln Gly Phe Pro Asp Trp Phe Arg Phe His Val 325 330 335 Thr Lys Trp His Ser Phe Arg Gln Ile Gly Asn Ser Val Ser Pro Ile 340 345 350 Val Ala Glu Tyr Ile Leu Lys Gly Leu Tyr Asn Leu Leu Asn Lys Arg 355 360 365 Val Gln Pro Glu Tyr Leu Asn His Asn Ser Leu Glu Val Arg Val * 370 375 380 <210> 884 <211> 330 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3628..4617) <400> 884 Met Ser Gly Gln Tyr Ile Pro Tyr His Leu Arg His Asn Lys Ser Ile 1 5 10 15 Asp Arg Glu Ile Phe Leu Glu Ser Leu Asn Leu Leu Ser Lys Arg Leu 20 25 30 Asn Ile Gln Glu Tyr Thr Tyr Ile Gly Phe Gly Gly Pro Met Leu Glu 35 40 45 Asp Phe Arg Ile Met His Asn Arg Ile Ala Leu Ser Asp Met Ile Ser 50 55 60 Leu Glu Glu Gln Glu Ser Thr His Ile Arg Gln Lys Tyr Asn Leu Pro 65 70 75 80 Tyr Asn Cys Ile Asp Cys Lys Leu Ile Ser Ala His Asp Phe Ile Leu 85 90 95 Asp Tyr Ser Phe Ser Lys Pro Ser Ile Thr Trp Leu Asp Tyr Ala Ser 100 105 110 Pro Lys Lys Ile Gln Thr Asp Leu Asp Asp Ile His Leu Leu Ser Thr 115 120 125 Lys Val Ser Ser Phe Asp Ile Leu Lys Val Thr Phe Pro Ile Asn Pro 130 135 140 Ser Ser Tyr Tyr Gln Arg Arg Val Gly Glu Ser Leu Asp Ile Phe Lys 145 150 155 160 Glu Ala Phe Ile Asn Ser Leu Lys Ser Leu Leu Gly Lys Lys Tyr Leu 165 170 175 Asp Phe Asn Leu Gln Ile Ser Asn Ala Asp Leu Ser Asp Arg Lys Ile 180 185 190 Lys Ala Leu Leu Ile Arg Ile Ile Thr Asn Ala Phe Arg Ser Ala Ile 195 200 205 Glu Arg Gly Leu Ser Gly Arg Lys Asp Lys Ile Gln Tyr Tyr Pro Leu 210 215 220 Ser Leu Asn Gln Tyr Asn Asp Gly Ser His Thr Met Leu Thr Ile Ser 225 230 235 240 Gly Phe Phe Ser Ser Glu Gln Glu Tyr Ile Glu Leu Ser Lys Ala Cys 245 250 255 Asp Leu Ser Asn Trp Gln Phe Tyr Ser Thr Asn Trp Glu Asp Val Gln 260 265 270 Glu Ile Ala Ile Pro Thr Leu Thr Ile Lys Glu Lys Ile Asn Leu Asp 275 280 285 Ser Lys Leu Pro Asp Lys Glu Ala Tyr Gln Ala Ala Ala Glu Glu Phe 290 295 300 Ser Leu Asn Glu Asn Glu Arg Asp Asn Tyr Tyr Lys Tyr Tyr Arg Leu 305 310 315 320 Tyr Pro Asn Phe Gln Arg Ile Met Val * 325 <210> 885 <211> 464 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4617..6008) <400> 885 Met Thr Glu Asn Thr Thr Pro Thr Ala Asp Phe Ser Pro Ser Lys Arg 1 5 10 15 Phe Phe Val Ser Met Leu Thr Arg Asp Ile Asp Leu Asn Asp Ala Ile 20 25 30 Leu Asp Leu Leu Asp Asn Cys Val Asp Gly Ala Leu Arg Thr Ile Lys 35 40 45 Asp Thr Lys Lys Thr Ser Lys Pro Tyr Glu Gly Phe Tyr Ala Lys Leu 50 55 60 Thr Ile Asn Lys Asp Val Phe Ile Ile Glu Asp Asn Cys Gly Gly Ile 65 70 75 80 Pro Lys Ser Phe Arg Glu Tyr Ala Phe Lys Met Gly Arg Pro His Gln 85 90 95 Lys Glu Glu Glu Asn Glu Gly Thr Val Gly Val Tyr Gly Ile Gly Met 100 105 110 Lys Arg Ala Ile Phe Lys Met Gly Arg Asp Cys Ser Ile Gln Ser Asn 115 120 125 Asn Pro Asp Gly Ala Phe Thr Val Asp Ile Thr Pro Asp Trp Ile Asp 130 135 140 Gly Asp Gly Trp Lys Ile Pro Met His Glu Ser Asp Tyr Asp Asn Lys 145 150 155 160 Asn Pro Thr Gly Thr Thr Ile Glu Ile Lys Lys Leu His Ser Asn Val 165 170 175 Ala Gln Lys Phe Asn Glu Ser Thr Tyr Leu Thr Asp Leu Phe Leu Gln 180 185 190 Ile Lys His Ser Leu Ser Phe Ile Ile Gln Lys Gly Phe Lys Ile Glu 195 200 205 Leu Asn Gly Val Val Val Glu His Asn Pro Ile Asn Ile Ile Thr Asp 210 215 220 His Ser Lys Ile Glu Pro Tyr Ile Tyr Lys Ala Lys Ile Asp Asp Val 225 230 235 240 Asp Ile Asp Leu Val Val Gly Phe Tyr Lys Asn Leu Glu Asp Asp Asn 245 250 255 Asp Asp Val Leu Glu Lys Arg Ser Ser Asp Asp Ala Gly Trp Thr Val 260 265 270 Ile Cys Asn Asp Arg Val Val Leu Tyr Cys Asp Lys Thr His Leu Thr 275 280 285 Gly Trp Gly Phe Ala Asn Val Pro Arg Phe His Thr Gln Phe Ile Ala 290 295 300 Ile Ser Gly Val Val Arg Phe Thr Ser Lys Asn Pro Glu Lys Leu Pro 305 310 315 320 Ile Thr Thr Thr Lys Arg Gly Val Asp Leu Ser Ser Thr Leu Tyr Asn 325 330 335 Asp Val Arg Asn Lys Met Ile Glu Gly Met Met His Phe Ile Arg Phe 340 345 350 Thr Asn Gln Trp Lys Gly Glu His Leu Glu Glu Gly Lys Lys Leu Leu 355 360 365 Lys Ser Ala Gln Ser His Glu Ala Gln Ser Leu Phe Glu Ile Thr Pro 370 375 380 Gln Ser Thr Pro Glu Asp Lys Lys Asn Asn Trp Ser Asn Pro Asn Arg 385 390 395 400 Asn Lys Asn Glu Trp Arg Tyr Thr Pro Lys Leu Pro Thr Pro Val Lys 405 410 415 Lys Ser Ser Thr Val Arg Ile Ile Phe Thr Arg Glu Lys Glu Asp Val 420 425 430 Lys Ile Leu Ser Lys Tyr Phe Phe Gly His Glu Asp Ala Ser Ala Ser 435 440 445 Asp Val Gly Met Gln Cys Phe Asp Thr Val Ile Glu Glu Val Lys * 450 455 460 <210> 886 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6508..7107) <400> 886 Met Ala His Ile Gln Leu Val Lys Gln Thr Ser Ser Gly Leu Leu Leu 1 5 10 15 Pro Ala Thr Pro Glu Ser Cys Asp Phe Leu His Gln Ile Lys Ile Gly 20 25 30 Glu Trp Ile His Ala Asp Phe Lys Arg Val Arg Asn Tyr Ala Phe His 35 40 45 Lys Arg Phe Phe Lys Leu Leu Gln Leu Gly Phe Asp Tyr Trp Thr Pro 50 55 60 Val Gly Gly Ala Ile Thr Pro Arg Glu Arg Glu Leu Leu Ser Gly Phe 65 70 75 80 Val Asp Tyr Leu Cys Glu Ser Val Gly Arg Glu His Thr Pro Ala Leu 85 90 95 Ser Asp Ala Ala Glu Gln Tyr Leu Asn Thr Val Ala Thr Arg Arg Thr 100 105 110 Arg Asp Thr Ala Leu Leu Lys Ser Phe Glu Ala Phe Arg Glu Trp Val 115 120 125 Thr Ile Gln Ala Gly Phe Tyr Thr Glu His Ile Tyr Pro Asp Gly Ser 130 135 140 Arg Gly Arg Arg Ala Lys Ser Ile Ala Phe Ala Asn Met Asp Glu Val 145 150 155 160 Glu Phe Gln Gln Val Tyr Lys Ser Val Leu Asn Val Leu Trp Asn Trp 165 170 175 Ile Leu Phe Arg Lys Phe Ser Ser Gln Glu Glu Val Glu Asn Val Ala 180 185 190 Ala Gln Leu Leu Glu Phe Ala * 195 <210> 887 <211> 97 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7107..7397) <400> 887 Met Val Asn Leu Arg Lys Ala Ala Lys Gly Gln Ile Cys Gln Ile Arg 1 5 10 15 Ile Pro Gly Tyr Cys Asn His Asn Pro Glu Thr Ser Val Leu Ala His 20 25 30 Tyr Arg Leu Ala Gly Thr Cys Gly Thr Ala Ile Lys Pro His Asp Met 35 40 45 Gln Ala Ala Ile Ala Cys Asn Ser Cys His Asp Leu Ile Asp Gly Arg 50 55 60 Val Lys Thr Ser Asp Tyr Thr Lys Glu Glu Leu Arg Leu Met His Ala 65 70 75 80 Glu Gly Val Phe Arg Thr Gln Glu Ile Trp Arg Lys Asp Gly Tyr Leu 85 90 95 * <210> 888 <211> 185 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7394..7948) <400> 888 Met Ile Tyr Pro Thr Asn Thr Gly Lys Ser Gly Glu His Leu Arg Leu 1 5 10 15 Thr Thr Leu Glu Ser Val Trp Ile Gln Gly Lys Leu Arg Met Trp Gly 20 25 30 Arg Trp Ser Tyr Ile Gly Gly Gly Lys Thr Gly Asn Met Phe Asn Gln 35 40 45 Leu Leu Thr Ser Lys Lys Leu Thr Lys Thr Ala Ile Asn Glu Ala Leu 50 55 60 Arg Arg Met Lys Lys Ala Gly Leu Asp Lys Pro Lys Leu Glu Ala Phe 65 70 75 80 Leu Arg Asp Met Ile Asn Gly Lys Gln Lys Ser Trp Leu Val His Cys 85 90 95 Thr Asp Ser Glu Ala Leu Ile Ile Asp Arg Val Ile Gly Glu Val Leu 100 105 110 Ala Gly Tyr Pro Gly Leu Leu Asn Val Leu Ser Gln Arg Tyr Val Gly 115 120 125 Arg Gly Met Thr Lys Arg Lys Met Ala Glu Leu Leu Asn Asp Ala His 130 135 140 Pro Glu Trp Ser Leu Arg Thr Cys Glu Arg Arg Ile Glu His Trp Leu 145 150 155 160 Lys Val Ala Glu Phe Ile Leu Tyr Lys Pro Met Val Met Ala Phe Gly 165 170 175 Ile Glu Lys Lys Val Ile Ala Phe * 180 <210> 889 <211> 144 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8510..8941) <400> 889 Met Phe Gly Ile Phe Lys Lys Lys Thr Arg Arg Ala Ala Ala Glu Ile 1 5 10 15 Lys Lys Phe Glu Lys Arg Asp Leu Ala Gln Ala Val Ile Asn Ala Ala 20 25 30 Tyr Leu Val Ala Tyr Ala Asp Gly Glu Cys Glu Ala Ser Glu Lys Ala 35 40 45 Lys Ile Glu Gln Val Leu Arg Asn Gln Pro Ala Leu Ser Ala Phe Thr 50 55 60 Ser Glu Ile Asn Ala Ile Ser Ala Thr Ile Ile Gly Gln Leu Asp Thr 65 70 75 80 Asn Phe Lys Ile Gly Arg Arg Ala Ala Leu Arg Glu Ile Glu Asp Val 85 90 95 Lys His Asp Thr Arg Glu Ala Glu Asp Val Leu Asp Val Ala Val Ala 100 105 110 Ile Ala Glu Ala Asp Gly Glu Ile Glu Pro Glu Glu Arg Lys Val Leu 115 120 125 Glu Glu Ile Ala Gly Val Leu Gly Leu Arg Leu Glu Asn His Leu * 130 135 140 <210> 890 <211> 56 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8938..9105) <400> 890 Val Thr Val Lys Leu Arg Leu Ala Val Ala Ala Leu Leu Leu Phe Leu 1 5 10 15 Val Val Met Val Asp Phe Thr Ser Arg Ile Met Ser Val Leu Ala Asp 20 25 30 Gly Val Leu Val Cys Gly Ile Val Val Leu Leu Trp Pro Val Ile Lys 35 40 45 Arg Asn Ser Leu His Asn Ala * 50 55 <210> 891 <211> 618 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9516..11369) <400> 891 Met Thr Phe Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Glu Lys Leu Thr His Lys Leu Lys Glu Gly Trp Gln Pro Tyr 20 25 30 Gly Gly Pro Val Ala Ile Thr Pro Tyr Thr Leu Met Gln Ala Val Ala 35 40 45 Ile Glu Gly Glu Pro Gln Val Gly Pro Ser Ser Glu Pro Asp Trp Tyr 50 55 60 Tyr Val Ile Val Leu Ala Gly Gln Ser Asn Ala Met Ala Tyr Gly Glu 65 70 75 80 Gly Leu Pro Leu Pro Asp Ser Tyr Asp Ala Pro Asp Pro Arg Ile Lys 85 90 95 Gln Leu Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Ala Ala Cys Arg 100 105 110 Tyr Asn Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln Asp 115 120 125 Met Ser Thr Leu Asn His Pro Arg Ala Asp Leu Ser Lys Gly Gln Tyr 130 135 140 Gly Cys Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro Tyr 145 150 155 160 Ile Pro Asn Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly Gly 165 170 175 Ser Ala Phe Thr Gln Gly Ala Glu Gly Thr Phe Ser Glu Ser Thr Gly 180 185 190 Ala Ser Gln Asp Ser Ala Arg Trp Gly Val Gly Lys Pro Leu Tyr Gln 195 200 205 Asp Leu Ile Ser Arg Thr Lys Ala Ala Leu Gln Lys Asn Pro Lys Asn 210 215 220 Val Leu Leu Ala Val Cys Trp Met Gln Gly Glu Phe Asp Met Ser Ala 225 230 235 240 Ala Thr His Ala Gln Gln Pro Ala Leu Phe Thr Ala Met Leu Thr Gln 245 250 255 Phe Arg Ala Asp Leu Ser Val Phe Asn Ala Gln Cys His Gly Gly Ser 260 265 270 Ala Ala Asp Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Tyr Trp Lys 275 280 285 Asn Thr Tyr Ala Thr Gln Tyr Asp Thr Val Tyr Gly Gly Tyr Lys Asn 290 295 300 Arg Glu Ser Glu Gly Val Tyr Phe Val Pro Phe Met Thr Asp Gly Asn 305 310 315 320 Gly Val Asn Thr Ala Thr Asn Ala Pro Ala Glu Asp Pro Asp Ile Pro 325 330 335 Ala Ser Gly Tyr Tyr Gly Ala Ala Ser Arg Thr Asn Gly Asn Gln Val 340 345 350 Ser Ser Asn Arg Pro Thr His Phe Ser Ser Trp Ala Arg Arg Ser Ile 355 360 365 Ile Pro Asp Arg Leu Ala Thr Ala Ile Leu Asn Ala Ala Gly Arg Thr 370 375 380 Ser Ala Phe Ile Ser Gly Lys Ala Pro Glu Ile Lys Pro Ser Pro Gly 385 390 395 400 Gly Asn Thr Pro Ser Gly Pro Ser Ala Asp Thr Ser Val Arg Thr Ile 405 410 415 Ser Leu Leu Pro Ala Ala Gly Glu Ala Ala Ala Gln Gly Trp Ser Ile 420 425 430 Lys Asp Gly Gly Ile Gln Leu Ser Asp Gly Val Phe Lys Ile Thr Arg 435 440 445 Gln Ser Asn Lys Thr Trp Ser Leu Thr His Pro Val Asp Asp Ala Ile 450 455 460 Thr Leu Leu Thr Gln Gly Gly Arg Leu Asn Cys Lys Phe Arg Leu Ser 465 470 475 480 Gly Ala Leu Thr Asn Asn Gln Phe Gly Leu Gly Ile Tyr Leu Tyr Thr 485 490 495 Asp Ala Pro Val Pro Asp Gly Val Ala Met Thr Gly Thr Gly Asn Pro 500 505 510 Phe Leu Met Ser Tyr Phe Thr Gln Thr Thr Asp Gly Arg Val Asn Leu 515 520 525 Met His His Arg Lys Ala Gly Asn Thr Lys Leu Gly Glu Phe Gly Asp 530 535 540 Tyr Gly Asn Asp Trp Gln Thr Leu Glu Leu Val Phe Thr Ala Gly Ser 545 550 555 560 Ala Thr Val Thr Pro Lys Leu Asn Gly Val Ala Gly Pro Ala Phe Gln 565 570 575 Val Ile Lys Asp Ser Leu Thr Leu Gly Leu Asn Ala Leu Thr Leu Thr 580 585 590 Asp Val Thr Lys Asn Ala Ala Tyr Gly Val Glu Ile Glu Ser Leu Val 595 600 605 Leu Glu Ile Asn Ala Pro Ala Ser Ser * 610 615 <210> 892 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11519..11734) <400> 892 Met Tyr Gln Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser 1 5 10 15 Ala Val Gly Thr Gly Tyr Trp Leu Leu Gln Leu Leu Asp Lys Val Ser 20 25 30 Pro Ser Gln Trp Val Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly 35 40 45 Leu Leu Thr Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Arg Glu Asp Arg 50 55 60 Arg Lys Thr Ala Arg Gly Asp * 65 70 <210> 893 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11739..12083) <400> 893 Met Lys Lys Lys Tyr Glu Leu Val Val Lys Glu Ile Asn Asn Tyr Pro 1 5 10 15 Asp Lys Ile Ala Val Thr Val Ala Leu Glu Ile Gly Gly His Pro Ser 20 25 30 Leu Leu Leu Pro His Val Ala Ile Ser Leu Asp Arg Thr Glu Gly Ala 35 40 45 Thr Leu Glu Phe Tyr Glu Ala Glu Ala Lys Lys Gln Ala Lys Gln Phe 50 55 60 Phe Met Asp Val Ala Ala Gly Leu Cys Glu Gly Asp Gly Pro Leu Pro 65 70 75 80 Glu Lys Arg Pro Val Ile Leu Glu Ala Gln Asp Val Leu Ile Thr Tyr 85 90 95 Arg Gly Lys Leu Pro Gly Ile Ile Thr Gly Ser Leu Lys Thr Pro Pro 100 105 110 Leu Ala * <210> 894 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12134..12667) <400> 894 Met Asn Ala Lys Ile Arg Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Gly Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Thr Arg Gly Asp Gly Lys Pro Val Ile 50 55 60 Pro Gly Met Lys Leu Ser Lys Glu Lys Cys Asp Arg Val Asn Ala Ile 65 70 75 80 Glu Arg Asp Lys Ala Leu Ala Trp Val Glu Lys Asn Ile Arg Val Pro 85 90 95 Leu Thr Glu Pro Gln Lys Ala Gly Ile Ala Ser Phe Cys Pro Tyr Asn 100 105 110 Ile Gly Pro Gly Lys Cys Phe Pro Ser Thr Phe Tyr Arg Arg Ile Asn 115 120 125 Ala Gly Asp Arg Lys Gly Ala Cys Glu Ala Ile Arg Trp Trp Ile Lys 130 135 140 Asp Gly Gly Arg Asp Cys Arg Ile Arg Ser Asn Asn Cys Tyr Gly Gln 145 150 155 160 Val Ser Arg Arg Asp Gln Glu Ser Ala Leu Ala Cys Trp Gly Ile Asp 165 170 175 Arg * <210> 895 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12938..13507) <400> 895 Met Asn Met Met Ala Val Pro Phe His Gly Asn Ser Leu Tyr Val Val 1 5 10 15 Asn His Asn Gly Glu Pro Tyr Val Pro Met Lys Pro Val Val Ala Gly 20 25 30 Met Gly Leu Ala Trp Gln Ser Gln Leu Ala Lys Leu Arg Gln Arg Phe 35 40 45 Ala Ser Thr Ile Thr Glu Ile Val Met Val Ala Glu Asp Gly Lys Gln 50 55 60 Arg Asn Met Val Ser Met Pro Leu Arg Lys Leu Ala Gly Trp Leu Gln 65 70 75 80 Thr Ile Asn Pro Asn Lys Val Lys Pro Glu Ile Arg Asp Lys Val Ile 85 90 95 Arg Tyr Gln Glu Glu Cys Asp Asp Val Leu Tyr Glu Tyr Trp Thr Lys 100 105 110 Gly Phe Val Val Asn Pro Arg Lys Met Ser Val Met Glu Glu Leu Asn 115 120 125 Gln Ala Cys Ala Asp Met Lys Arg Asp Lys Asn Ile Ala Ser Val Phe 130 135 140 Ala Thr Gly Leu Asn Glu Trp Lys Gln Val Lys Ala Ala His Val Ser 145 150 155 160 Lys Ile Arg Thr Leu Val Asn Glu Ala Asn Met Leu Ile Asp Phe Val 165 170 175 Leu Ala Asp Thr Gly Lys Gly Lys Ile Thr Lys Ala Asp * 180 185 <210> 896 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13661..14128) <400> 896 Met Asn Arg Val Leu Cys Val Val Ile Ile Val Leu Ala Val Gly Tyr 1 5 10 15 Gly Ala Leu Trp Leu Ala Thr Asn His Tyr Arg Asp Asn Ala Leu Thr 20 25 30 Tyr Lys Ala Gln Arg Asp Lys Lys Ala Arg Glu Leu Glu Gln Ala Asn 35 40 45 Ala Thr Ile Thr Asp Met Gln Val Arg Gln Arg Asp Val Ala Ala Leu 50 55 60 Asp Ala Lys Tyr Ser Arg Glu Leu Ala Asp Ala Arg Ala Glu Asn Glu 65 70 75 80 Thr Leu Arg Ala Asp Val Ala Ala Gly Arg Lys Arg Leu Arg Ile Asn 85 90 95 Ala Thr Cys Ser Gly Thr Val Arg Glu Ala Thr Gly Thr Ser Gly Val 100 105 110 Asp Asn Ala Thr Gly Pro Arg Leu Ala Asp Thr Ala Glu Arg Asp Tyr 115 120 125 Phe Ile Leu Arg Glu Arg Leu Met Thr Met Gln Lys Gln Leu Glu Gly 130 135 140 Ala Gln Asp Tyr Ile Arg Thr Gln Cys Leu Asn * 145 150 155 <210> 897 <211> 76 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14491..14718) <400> 897 Met Ser Ser Lys Asn Arg Pro Arg Arg Thr Thr Thr Arg Asn Ile Arg 1 5 10 15 Phe Pro Asn Gln Met Ile Glu Gln Ile Asn Ile Ala Leu Asp Gln Lys 20 25 30 Gly Ser Glu Asn Phe Ser Ala Trp Val Ile Glu Ser Cys Arg Arg Glu 35 40 45 Leu Ala Ala Asp Ile Lys Tyr Ala Arg Gln Leu Thr Ile Lys Lys Asn 50 55 60 Asp Thr Gln Tyr Ala Leu Arg Trp Leu Phe Ile * 65 70 75 <210> 898 <211> 122 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14760..15125) <400> 898 Met Ala Val Leu Arg Thr Leu Pro Gly Arg Ile Lys Thr Leu Asn Thr 1 5 10 15 Arg Arg Ile Asn Val Leu Arg Gly Glu Gln Arg Arg Val Ser Gly Ser 20 25 30 Ala Arg Val Ser Leu Lys Arg Arg Ile Trp Arg Arg Asp Ala Gly His 35 40 45 Cys Cys Leu Cys Arg Arg Val Val Asp Leu Cys Asp Ser Glu Leu Asp 50 55 60 His Arg Ile Ala Leu Gln Phe Gly Gly Gly Asn Glu Glu Thr Asn Leu 65 70 75 80 Trp Thr Leu Cys Thr Glu Cys His Arg Gln Lys Ser Ala Ser Glu Ala 85 90 95 Ala Ser Gly Met Pro Asp Pro Thr Leu Pro Glu Leu Pro Asp Gly Thr 100 105 110 Leu Arg Ala Asp Gly Ile Thr Gly Leu * 115 120 <210> 899 <211> 48 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15088..15231) <400> 899 Met Ala Arg Ser Gly Pro Thr Glu Ser Leu Ala Cys Asp Gln Thr Arg 1 5 10 15 Gly Gly Ser Ser Gly Glu Lys Lys Arg Ser Pro Trp Thr Pro Arg Pro 20 25 30 Leu Ser Arg Arg Glu Lys Ile Pro Val Ser Gly Gln Leu Thr Cys * 35 40 45 <210> 900 <211> 188 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15415..15978) <400> 900 Val Leu Thr Thr Gln Lys Arg Lys Phe Ala Leu Ala Leu Met Ser Gly 1 5 10 15 Lys Asn Lys Thr Ala Ser Ala Leu Ala Ala Gly Tyr Ser Ala Lys Thr 20 25 30 Ala Arg Val Lys Gly Ser Gln Leu Ala Lys Asp Pro Glu Val Leu Ala 35 40 45 Phe Ile Ala Arg Lys Gln Cys Glu Thr Val Glu Val Asp Glu Val Pro 50 55 60 Val Tyr Arg Gln Lys Lys Ser Glu Pro Glu Asp Lys Pro Arg Arg Arg 65 70 75 80 Glu Ala Ala Ala Ile Pro Gln Pro Asp Glu Thr Asn Pro Glu Met Pro 85 90 95 Pro Pro Val Val Ile Ser Pro Gly Ile Glu Tyr Met Glu Asp Gly Leu 100 105 110 Pro Asp Pro Val Lys Ala Met Gly Arg Leu Leu Val Glu Asn Ile Asn 115 120 125 Thr Asp Pro Arg Leu Ala Leu Asp Ala Ala Tyr Lys Leu Ala Gln Phe 130 135 140 Thr His His Lys Lys Gly Asp Ala Gly Lys Lys Ser Ala Lys Gly Asp 145 150 155 160 Ala Ala Lys Lys Ala Ala Asn Arg Phe Ala Val Pro Pro Pro Pro Arg 165 170 175 Leu Val Val Asn Asn Asp Asn Glu Gly Asn Gly * 180 185 <210> 901 <211> 554 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15975..17636) <400> 901 Met Ile Pro Val Trp Ser Thr Ala Cys Pro Asp Trp Ala Glu Arg Leu 1 5 10 15 Lys Lys Gly Leu Ser Ile Ile Pro Ala Pro Ile Tyr Pro Glu Gln Ala 20 25 30 Ala His Ala Leu Ala Ile Phe Lys Gln Leu Arg Ile Val Asp Ala Pro 35 40 45 Gly Ser Pro Thr Phe Gly Glu Ser Cys Ala Gln Trp Val Phe Asp Leu 50 55 60 Val Ala Ala Leu Phe Gly Ser Tyr Asp Ala Gln Thr Gly Val Arg His 65 70 75 80 Ile Lys Glu Val Phe Ile Leu Ile Pro Lys Lys Asn Ser Lys Ser Thr 85 90 95 Leu Ala Ala Gly Ile Met Met Thr Ala Leu Leu Leu Asn Trp Arg Gln 100 105 110 Ala Ala Gly Tyr Thr Ile Leu Ala Pro Thr Val Glu Val Ala Ala Asn 115 120 125 Ala Phe Asn Pro Ala Arg Asp Met Val Arg Arg Asp Asp Asp Leu Asp 130 135 140 Asp Leu Cys Gln Val Gln Thr His Ile Arg Thr Ile Thr His Arg Val 145 150 155 160 Thr Asp Thr Thr Leu Lys Val Val Ala Ala Asp Pro Asn Thr Val Ser 165 170 175 Gly Ile Lys Ser Val Gly Thr Leu Ile Asp Glu Leu Trp Leu Phe Gly 180 185 190 Lys Gln Tyr Lys Ala Glu Asp Met Leu Arg Glu Ala Ile Gly Gly Leu 195 200 205 Ala Ser Arg Pro Glu Gly Phe Val Val Tyr Thr Thr Thr Gln Ser Asn 210 215 220 Glu Pro Pro Ala Gly Val Phe Arg Gln Lys Leu Gln Tyr Ala Arg Asp 225 230 235 240 Val Arg Asp Gly Lys Ile His Asp Pro His Phe Leu Pro Val Ile Phe 245 250 255 Glu His Pro Pro Glu Met Val Glu Ser Gly Ala His Leu Leu Met Glu 260 265 270 Asn Leu Ala Met Val Asn Pro Asn Leu Gly Tyr Ser Val Asp Glu Ala 275 280 285 Phe Leu Tyr Arg Glu Tyr Arg Lys Ala Arg Glu Ala Gly Glu Glu Ala 290 295 300 Phe Arg Gly Phe Met Ser Lys His Ala Asn Val Glu Ile Gly Leu Ala 305 310 315 320 Leu Arg Ser Asp Arg Trp Ala Gly Ala Asp Phe Trp Glu Gln Gln Gly 325 330 335 Arg Arg Val Ser Leu Asp Asp Ile Leu Gln Arg Ala Asp Val Val Thr 340 345 350 Val Gly Ile Asp Gly Gly Gly Leu Asp Asp Leu Leu Gly Met Tyr Val 355 360 365 Ile Gly Arg Asp Arg Glu Thr Arg Glu Trp Leu Gly Trp Gly His Ala 370 375 380 Trp Ala His Glu Thr Ala Val Val Arg Arg Lys Ser Glu Ala Ser Arg 385 390 395 400 Phe Gln Asp Leu Val Ala Cys Gly Asp Met Thr Ile Val Arg Arg Val 405 410 415 Gly Asp Asp Thr Ala Glu Val Ala Glu Tyr Val Arg Arg Ile His Glu 420 425 430 Ala Glu Leu Leu Asp His Ile Gly Ile Asp Pro Ser Gly Val Gly Gln 435 440 445 Ile Leu Asp Ser Leu Ala Glu Ala Gly Ile Pro Asp Gly Ile Val Val 450 455 460 Gly Ile Ser Gln Gly Trp Lys Leu Gly Gly Ala Ile Lys Thr Thr Glu 465 470 475 480 Arg Lys Leu Ala Glu Gly Val Leu Val His Gly Asp Gln Pro Leu Met 485 490 495 Ala Trp Cys Val Gly Asn Ala Arg Val Glu Pro Lys Gly Asn Ala Ile 500 505 510 Leu Ile Thr Lys Gln Ala Ser Gly Arg Gly Lys Ile Asp Pro Leu Met 515 520 525 Ala Leu Phe Asn Ala Val Ser Leu Met Ser Leu Asn Pro Glu Pro Lys 530 535 540 Lys Lys Glu Tyr Ala Val Phe Phe Ile * 545 550 <210> 902 <211> 646 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17700..19637) <400> 902 Val Thr Leu Lys Arg Ala Cys Ser Leu Leu Thr Val Lys Ser Phe Ser 1 5 10 15 Glu Asp Glu Arg Val Ile Thr Gly Ile Ala Ser Thr Pro Ser Pro Asp 20 25 30 Arg Asp Gly Asp Ile Leu Glu Pro Glu Gly Ala Glu Phe Gly Ser Ala 35 40 45 Ile Pro Phe Leu Trp Gln His Asp His Ser Arg Pro Val Gly Gln Cys 50 55 60 Thr Val Arg Arg Val Ser Glu Gly Leu Glu Ile Thr Ala Thr Leu Val 65 70 75 80 Lys Pro Val Pro Asp Met Pro Ser Gln Leu Ala Ala Arg Leu Asp Glu 85 90 95 Val Trp Ala Ala Ile Lys Thr Gly Leu Val Arg Gly Leu Ser Val Gly 100 105 110 Phe Arg Pro His Glu Tyr Thr Phe Leu Asp Gly Gly Gly Leu His Phe 115 120 125 Leu Arg Trp Glu Leu Met Glu Val Ser Ala Val Thr Val Pro Ala Asn 130 135 140 Ala Glu Cys Thr Ile Arg Thr Ile Lys Ser Tyr Asp Arg Pro Phe Ser 145 150 155 160 Ala Ala Ser Gly Asn Arg Lys Pro Val Val Lys Ile Ala Ser Ser Ala 165 170 175 Gly Ala Ala Ala Gln Ser Thr Thr Val Phe His Lys Glu Lys Thr Ile 180 185 190 Met Asn Ile Gly Glu Gln Ile Lys Ser Phe Glu Asn Lys Arg Ala Ala 195 200 205 Leu Ala Ala Ser Leu Glu Glu Val Met Thr Lys Ala Ala Glu Glu Gly 210 215 220 Arg Thr Leu Asp Val Glu Glu Glu Glu His Tyr Asp Asn Thr Ala Ala 225 230 235 240 Glu Ile Arg Gln Val Asp Ala His Leu Lys Arg Leu Arg Glu Leu Glu 245 250 255 Ala Gly Lys Ala Ala Thr Ala Gln Pro Val Lys Gln Ala Gly Asn Gly 260 265 270 Asn Val Ala Ala Val Ala Ser Ala Pro Val Ile Arg Val Glu Gln Lys 275 280 285 Leu Asp Lys Gly Ile Gly Phe Ala Arg Phe Ala Lys Ser Leu Ala Ala 290 295 300 Ala Lys Gly Val Arg Ser Glu Ala Leu Glu Val Ala Arg Arg Gln Tyr 305 310 315 320 Pro Asp Asp Ser Arg Leu His His Val Leu Lys Ser Ala Val Gly Ala 325 330 335 Gly Thr Thr Thr Asp Pro Gln Trp Ala Gly Ser Leu Ser Glu Tyr Gln 340 345 350 Glu Tyr Ala Gln Asp Phe Ile Asp Tyr Leu Arg Pro Gln Thr Ile Ile 355 360 365 Gly Arg Phe Gly Gln Gly Gly Ile Pro Ala Leu Arg Gln Val Pro Phe 370 375 380 Asn Ile Arg Val His Ala Gln Val Ser Gly Gly Ala Ala Gly Trp Val 385 390 395 400 Gly Glu Gly Lys Ala Lys Pro Leu Thr Lys Phe Asp Phe Glu Ser Ile 405 410 415 Thr Phe Ser His Ala Lys Val Ser Ala Ile Ala Val Leu Thr Glu Glu 420 425 430 Leu Ile Arg Phe Ser Ser Pro Ala Ala Asp Ala Leu Val Arg Asn Ala 435 440 445 Leu Ala Glu Ala Val Val Ala Arg Leu Asp Thr Asp Phe Val Asp Pro 450 455 460 Lys Lys Ala Ala Val Ala Asp Val Ser Pro Ala Ser Ile Thr His Asp 465 470 475 480 Val Lys Gly Thr Ala Ser Thr Gly Asn Pro Asp Ala Asp Ala Glu Ala 485 490 495 Ala Phe Gly Gln Phe Val Ala Ala Asn Leu Gln Pro Thr Gly Ala Val 500 505 510 Trp Leu Met Ser Ser Thr Asn Ala Leu Ala Leu Ser Met Arg Lys Asn 515 520 525 Ala Leu Gly Gln Lys Glu Tyr Pro Asp Met Thr Leu Leu Gly Gly Ser 530 535 540 Phe Gln Gly Leu Pro Val Ile Val Ser Gln Tyr Val Gly Asp Gln Leu 545 550 555 560 Val Leu Val Asn Ala Pro Asp Ile Tyr Leu Ala Asp Asp Gly Gly Val 565 570 575 Ala Val Asp Met Ser Arg Glu Ala Ser Leu Glu Met Gln Ser Glu Pro 580 585 590 Gly Gly Asp Ser Thr Thr Pro Ser Pro Val Glu Leu Val Ser Met Phe 595 600 605 Gln Thr Gly Ser Val Ala Ile Arg Ala Glu Arg Trp Ile Asn Trp Arg 610 615 620 Arg Arg Arg Thr Ala Ala Val Ala Val Ile Thr Gly Val Asn Tyr Gly 625 630 635 640 Ser Ala Ser Gly Gly * 645 <210> 903 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19713..19898) <400> 903 Met Met Pro Gly Pro Gly Ile Ser Val Met Trp His Ser Arg Val Arg 1 5 10 15 Arg Cys Trp Phe Ala Trp Gly Arg Arg Ser Thr Ser Gln Arg Asp Val 20 25 30 Arg Gln Val Arg Lys Arg Asn Val Met Arg Ser Met Ala Asn Val Glu 35 40 45 Pro Phe Ala Ala Asn Pro Lys Lys Pro Glu Ile Arg Thr * 50 55 60 <210> 904 <211> 455 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19849..21213) <400> 904 Met Trp Asn Leu Leu Arg Arg Thr Arg Lys Asn Gln Lys Ser Gly Arg 1 5 10 15 Asp Val Arg Glu Val Gly Trp Arg Ser Leu Phe Gln Ala Val Ala Glu 20 25 30 Pro Phe Ala Gly Ala Trp Gln Gln Gly Val Lys Ala Asp Pro Glu Thr 35 40 45 Val Leu Ser Phe His Ala Val Phe Ser Cys Ile Ser Leu Ile Ser Gln 50 55 60 Asp Ile Ala Lys Met Arg Leu Arg Leu Met Gln Thr Asp Val Gln Gly 65 70 75 80 Ile Arg Arg Glu Lys Arg Gln Gly Asp Thr Ala Arg Leu Cys Arg Arg 85 90 95 Pro Asn Ala Gln Gln Asn Arg Ile Gln Phe Phe Glu Leu Trp Leu Asn 100 105 110 Ser Lys Leu Arg His Gly Asn Thr Val Val Leu Lys Ile Arg Thr Pro 115 120 125 Arg Gly Gln Ile Lys Glu Leu Arg Ile Leu Asp Trp Asn Arg Val Glu 130 135 140 Pro Leu Val Ala Asp Asp Gly Glu Val Phe Tyr Arg Ile Thr Pro Asp 145 150 155 160 Arg Asn Cys Gly Ile Thr Glu Ser Val Thr Val Pro Ala Arg Glu Val 165 170 175 Ile His Asp Arg Phe Asn Cys Phe Phe His Pro Leu Val Gly Leu Pro 180 185 190 Pro Val Tyr Ala Ala Gly Leu Ala Ala Met Gln Gly His His Ile Gln 195 200 205 Ala Asn Ser Thr Tyr Phe Phe Arg Asn Gly Gly Arg Pro Ser Gly Val 210 215 220 Ile Glu Val Pro Gly Ser Ile Thr Glu Glu Asn Ala Lys Lys Leu Lys 225 230 235 240 Gly Asn Trp Asp Ser Gly Tyr Thr Gly Glu Asn Ala Gly Lys Thr Ala 245 250 255 Ile Leu Ser Asn Gly Ala Lys Tyr Ser Pro Thr Thr Phe Ser Pro Val 260 265 270 Asp Ala Gln Thr Val Glu Gln Leu Lys Met Thr Ala Glu Ile Val Cys 275 280 285 Ser Val Phe Arg Val Pro Ala Tyr Lys Ile Gly Val Gly His Pro Pro 290 295 300 Ser Ser Asp Asn Val Glu Ala Leu Glu Gln Gln Tyr Tyr Ser Gln Cys 305 310 315 320 Leu Gln Thr Leu Ile Glu Ser Ile Glu Leu Leu Leu Asp Glu Ala Leu 325 330 335 Glu Thr Gly Glu Asn Glu Ser Thr Glu Phe Asp Val Thr Thr Leu Leu 340 345 350 Arg Met Asp Ser Glu Arg Arg Met Lys Thr Leu Gly Glu Ser Val Lys 355 360 365 Asn Thr Leu Leu Thr Pro Asn Glu Ala Arg Lys Arg Glu Asn Leu Pro 370 375 380 Pro Leu Ala Gly Gly Asp Ala Leu Tyr Leu Gln Gln Gln Asn Tyr Ser 385 390 395 400 Leu Glu Ala Leu Ser Arg Arg Asp Ala Arg Glu Asp Pro Phe Ala Ser 405 410 415 Ala Gly Lys Thr Val Ser Ala Gln Leu Pro Asp Gly Ala Ser Asp Gly 420 425 430 Asn Lys Ala Ile Ser Glu Thr Glu His Asp Ala Val Lys Ala Met Phe 435 440 445 Arg Gly Ile Leu Arg Lys * 450 <210> 905 <211> 408 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21210..22433) <400> 905 Met Thr Glu Arg Glu Leu Ser Ile Ile Arg Ala Leu Gly Glu Glu Phe 1 5 10 15 Ser Thr Val Leu Ala Asp Leu Gln Arg Thr Phe Glu Gly Lys Met Ala 20 25 30 Ala Gln Ala Gln Ala Phe Glu Glu Lys Leu Ala Ser Leu Ser Ala Val 35 40 45 Leu Gln Lys His Val Thr Val Asp Glu Val His Pro Val Leu Gln Ala 50 55 60 Met Val Asp Asp Ala Val Gly Thr Ile Pro Val Pro Arg Asp Gly Arg 65 70 75 80 Asp Tyr Asp Pro Asp Val Leu Gln Gln Ala Val Asn Asp Ala Val Ala 85 90 95 Asn Ile Pro Val Pro Ala Asp Gly Lys Ser Ile Thr Pro Asp Asp Val 100 105 110 Arg Pro Met Leu Glu Gln Met Val Lys Glu Ala Val Ser His Ile Pro 115 120 125 Ala Pro Arg Asp Gly Arg Asp Tyr Asp Pro Glu Val Leu Lys Gln Ala 130 135 140 Val Asn Asp Ala Val Ala Asn Ile Pro Val Pro Ala Asp Gly Lys Ser 145 150 155 160 Ile Thr Pro Asp Asp Val Arg Pro Met Leu Glu Gln Met Val Lys Glu 165 170 175 Ala Val Ser His Ile Pro Ala Pro Arg Asp Gly Arg Asp Tyr Asp Pro 180 185 190 Glu Val Leu Lys Gln Ala Val Asn Asp Ala Val Ala Asn Ile Pro Val 195 200 205 Pro Ala Asp Gly Lys Ser Ile Thr Pro Asp Asp Val Arg Pro Met Leu 210 215 220 Glu Gln Met Val Lys Glu Ala Val Ser His Ile Pro Val Pro Arg Asp 225 230 235 240 Gly Arg Asp Tyr Asp Pro Asp Val Leu Gln Lys Ala Val Leu Asp Ala 245 250 255 Val Arg Ala Leu Pro Ala Pro Gln Asp Gly Arg Asp Ala Thr Ala Leu 260 265 270 Glu Ile Ile Pro Ala Ile Asp Asp Gln Lys Ser Phe Pro Arg Gly Thr 275 280 285 Tyr Ala Thr His Gln Gly Gly Leu Trp Arg Ala Tyr Glu Lys Thr His 290 295 300 Gly Met Arg Gly Trp Glu Cys Leu Val Asp Gly Val Ala Asp Ile Asp 305 310 315 320 Val Ser Met Thr Gly Glu Arg Ser Phe Thr Val Val Val Arg Gln Ser 325 330 335 Ser Gly Gln Arg Thr Glu Lys Thr Phe Ser Leu Pro Val Met Leu Tyr 340 345 350 Arg Gly Val Phe Arg Ala Gly Glu Thr Tyr His Pro Gly Asp Thr Val 355 360 365 Thr Trp Gly Gly Ser Leu Trp His Cys Asn Ser Met Thr Gly Asp Lys 370 375 380 Pro Gly Glu Ala His Ser Ser Gly Trp Thr Leu Ala Ala Lys Arg Gly 385 390 395 400 Arg Asp Ala Gly Gly Gly Lys * 405 <210> 906 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22430..22756) <400> 906 Met Thr Ala Leu Leu Thr Leu Glu Glu Ile Lys Ala His Leu Arg Val 1 5 10 15 Asp His Asp Ala Asp Asp Asp Met Leu Met Asp Lys Val Arg Gln Ala 20 25 30 Thr Ala Val Leu Leu Ala Tyr Ile Gln Gly Ser Arg Asp Lys Val Ile 35 40 45 Arg Glu Asp Gly Glu Leu Ile Pro Gly Glu Ala Leu Thr Arg Met Lys 50 55 60 Gly Ala Ala Met Arg Leu Thr Gly Met Leu Tyr Arg Asn Pro Asp Leu 65 70 75 80 Ala Glu Arg Glu Asp Leu Val Gln Gly Glu Leu Pro Phe Ser Val Ser 85 90 95 Val Leu Ile Tyr Asp Leu Arg Cys Pro Thr Val Leu * 100 105 <210> 907 <211> 117 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22766..23116) <400> 907 Met Ala Ile Ser Ala Gly Arg Leu Thr Gln Met Ile Ser Val Leu Asn 1 5 10 15 Pro Val Leu Thr Arg Asn Ala Ala Gly Glu Met Thr Glu Glu Trp Val 20 25 30 Ser Cys Gly Lys Ile His Ala Asp Ile Arg Gly Arg Ser Ser Arg Glu 35 40 45 Arg Met Gln Ser Gly Ala Glu Met Ala Gln Ala Glu Ile Arg Ile Trp 50 55 60 Val Arg Gly Gln Ser Gly Arg Glu Ile Thr Ala Ala Ser Arg Leu His 65 70 75 80 Val Leu Ser Gly Pro Trp Arg Asp Arg Ile Leu Asn Val Val Gly Leu 85 90 95 Pro Val Pro Asp Val Thr Gly Gly Arg Leu Glu Ile Leu Cys Arg Leu 100 105 110 Gly Gly Glu Lys * 115 <210> 908 <211> 149 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23113..23559) <400> 908 Met Ile Glu Thr Leu Leu Asp Phe Ser Gly Leu Glu Asp Ile Ser Arg 1 5 10 15 Asp Leu Gln Leu Leu Ser Gly Ala Glu Asn Asn Arg Val Leu Arg Glu 20 25 30 Ala Thr Arg Ala Gly Ala Asn Val Leu Lys Glu Glu Val Val Ser Arg 35 40 45 Ala Pro Val Arg Arg Gly Lys Leu Arg Arg Asn Val Val Val Leu Ser 50 55 60 Arg Arg Ser Arg Asp Gly Gly Met Glu Ser Gly Val His Ile Arg Gly 65 70 75 80 Val Asn Pro Asp Thr Gly Asn Ser Asp Asn Thr Met Lys Ala Asp Asn 85 90 95 Pro Arg Asn Ala Phe Tyr Trp Arg Phe Val Glu Met Gly Thr Val Asn 100 105 110 Met Pro Pro His Pro Phe Val Arg Pro Ala Phe Asp Val Arg Ser Glu 115 120 125 Gln Ala Ala Gln Val Ala Ile Ala Arg Met Asn Arg Ala Ile Asp Glu 130 135 140 Val Leu Arg Arg * 145 <210> 909 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23556..23900) <400> 909 Met Thr Glu Ala Asp Leu Tyr Pro Tyr Leu Ala His Leu Ala Gly Gly 1 5 10 15 Gln Val Tyr Pro Tyr Val Val Pro Leu Leu Asp Gly Arg Pro Ser Val 20 25 30 Ala Leu Pro Trp Val Val Phe Ser Leu Ile Ser Ser Val Ser Ala Asp 35 40 45 Val Met Gly Gly Gln Ala Glu Ser Ser Val Ser Val Gln Ile Asp Val 50 55 60 Tyr Ala Gly Thr Val Thr Gln Ala Arg Gln Ile Arg Gln Asp Ala Arg 65 70 75 80 Glu Ala Ile Met Leu Leu Ala Pro Gly Ser Val Ser Glu Met Gln Asp 85 90 95 Tyr Ile Pro Glu Asn Arg Cys Tyr Arg Ala Thr Leu Glu Phe Gln Val 100 105 110 Thr Val * <210> 910 <211> 239 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23969..24685) <400> 910 Met Ser Ala Leu Tyr Glu Arg Ser Gln Leu Thr Gln Val Met Ile Ser 1 5 10 15 Ser Ala Pro Ala Thr Ala Glu Thr Met Asp Lys Ala Glu Tyr Leu Arg 20 25 30 Leu Asp Cys Thr Ile Lys Glu Val Gln Phe Thr Ala Gly Gln Lys Gln 35 40 45 Asp Ile Asp Val Thr Thr Leu Cys Ser Thr Glu Gln Glu Asn Ile Asn 50 55 60 Gly Leu Gly Ala Ser Ser Glu Ile Ser Met Ser Gly Asn Phe Tyr Leu 65 70 75 80 Asn Gln Ala Gln Asn Ala Leu Arg Asp Ala Tyr Asp Asn Asp Thr Val 85 90 95 Tyr Ala Phe Lys Val Gln Phe Pro Ser Gly Lys Gly Phe Lys Phe Leu 100 105 110 Ala Glu Val Arg Gln His Thr Trp Ser Ser Gly Thr Asn Gly Val Val 115 120 125 Ala Ala Thr Phe Ser Leu Arg Leu Lys Gly Lys Pro Val Ser Tyr Val 130 135 140 Val Pro Leu Ala Phe Val Lys Asn Pro Glu Lys Thr Leu Thr Val Asn 145 150 155 160 Thr Gly Ala Leu Leu Thr Met Ser Val Ser Val Asn Gly Gly Thr Pro 165 170 175 Pro Tyr Lys Tyr Ala Trp Lys Lys Asp Gly Gln Pro Val Glu Gly Gln 180 185 190 Thr Thr Asp Thr Phe Ser Lys Ala Asn Ala Gln Ser Gly Asp Lys Gly 195 200 205 Ala Tyr Thr Cys Met Val Met Asp Ser Ala Glu Gln Pro Gln Ser Ile 210 215 220 Thr Ser Asp Ala Cys Thr Val Thr Val Asn Gly Ala Gly Gly * 225 230 235 <210> 911 <211> 125 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24691..25065) <400> 911 Met Ala Lys Asp Leu Lys Thr Leu Ala Leu Ala Arg Leu Ser Gly Phe 1 5 10 15 Arg His Lys Thr Val Lys Val Pro Glu Trp Arg Asn Val Ser Val Val 20 25 30 Leu Arg Glu Pro Ser Ala Glu Ala Trp Tyr Leu Trp Gln Glu Val Leu 35 40 45 Asn Gly Asp Gly Glu Asp Asp Asp Thr Leu Ser Val Val Ala Lys Thr 50 55 60 Arg Arg Asn Leu Glu Ala Asp Val Thr Leu Phe Cys Asp Val Leu Cys 65 70 75 80 Asp Thr Asp Leu Gln Arg Val Phe Ala Pro Asp Asp Arg Glu Gln Val 85 90 95 Leu Ala Val Tyr Gly Pro Val His Ala Arg Leu Leu Arg Gln Ala Leu 100 105 110 Glu Leu Ile Ala Asp Ala Glu Ser Ala Arg Lys Lys * 115 120 <210> 912 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25089..25370) <400> 912 Met Arg Leu Ala Leu Arg Leu Gly Arg Thr Leu Ser Glu Leu Arg His 1 5 10 15 Ser Leu Ser Ala Ser Glu Ala Met Met Trp Met Glu Phe Asp Arg Val 20 25 30 Ser Pro Leu Gly Asp Glu Arg Gly Asp Ile Arg Asn Ala Gln Ile Val 35 40 45 Lys Ala Val Phe Gly Ala Gln Gly Met Asn Val Ala Leu Lys Asp Ala 50 55 60 Met Leu Cys Trp Gly Glu Asp Glu Asp Lys Pro Glu Val Asp Pro Phe 65 70 75 80 Ala Ala Leu Glu Asp Ala Leu Ser Leu Ala Ala Met Ser * 85 90 <210> 913 <211> 1027 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25422..28502) <400> 913 Met Ala Thr Leu Arg Glu Leu Ile Ile Lys Ile Ser Ala Asn Ser Gln 1 5 10 15 Ser Phe Gln Ser Glu Ile Gln Arg Ala Ser Arg Met Gly Ser Glu Tyr 20 25 30 Tyr Arg Thr Leu Gln Asn Gly Gly Arg Gln Ala Ala Ala Ala Ala Arg 35 40 45 Asp Gln Arg Arg Ala Leu Ala Glu Leu Asn Ser Gln Leu Thr Glu Ile 50 55 60 Arg Gly Ser Ala Val Gly Met Ala Gly Ala Phe Ala Gly Ala Phe Ala 65 70 75 80 Thr Gly His Leu Ile Ser Leu Ala Asp Glu Trp Ser Ser Val Asn Ala 85 90 95 Arg Leu Lys Gln Ala Ser Gln Ser Ser Asp Glu Phe Ser Ser Ser Gln 100 105 110 Lys Val Leu Met Asp Ile Ser Gln Arg Thr Gly Thr Ala Phe Ser Asp 115 120 125 Asn Ala Ala Leu Phe Ala Arg Ser Ala Ala Ser Met Arg Glu Tyr Gly 130 135 140 Tyr Ser Ala Asp Asp Val Leu Lys Val Thr Glu Ala Ile Ser Thr Gly 145 150 155 160 Leu Lys Ile Ser Gly Ala Ser Thr Ala Glu Ala Gly Ser Val Ile Thr 165 170 175 Gln Phe Ser Gln Ala Leu Ala Gln Gly Val Leu Arg Gly Glu Glu Phe 180 185 190 Asn Ser Val Asn Glu Ser Gly Asp Arg Ile Val Arg Ala Leu Ala Ala 195 200 205 Gly Met Gly Val Ala Arg Lys Asp Leu Lys Ala Met Ala Asp Asp Gly 210 215 220 Gln Leu Thr Ala Asp Lys Val Val Pro Ala Leu Ile Ser Gln Leu Glu 225 230 235 240 Val Leu Arg Asp Glu Tyr Ala Ala Met Pro Glu Thr Val Ser Asp Gly 245 250 255 Ile Thr Lys Val Glu Asn Ala Phe Met Ala Trp Val Gly Gly Ala Asn 260 265 270 Glu Ala Ser Gly Val Thr Lys Thr Leu Ser Gly Val Leu Asn Gly Val 275 280 285 Ala Gly Gln Ile Asp Asn Val Ala Thr Ala Val Gly Ala Leu Val Ala 290 295 300 Val Gly Val Ala Arg Tyr Phe Gly Asn Met Ala Ser Gly Ala Met Ser 305 310 315 320 Ala Thr Ala Gly Leu Val Thr Ala Ala Arg Asn Glu Val Ala Leu Ala 325 330 335 Glu Ala Gln Phe Arg Gly Thr Gln Ile Ala Thr Ala Arg Ala Arg Ala 340 345 350 Ala Val Tyr Arg Ala Gln Gln Ala Val Ala Ala Ala Arg Gly Thr Glu 355 360 365 Met Gln Ile Ala Ala Glu Ala Arg Leu Ala Ala Thr Gln Glu Arg Leu 370 375 380 Asn Arg Asn Ile Ala Ala Arg Ser Ala Ala Gln Asn Ala Leu Asn Ser 385 390 395 400 Thr Thr Ala Val Gly Ser Arg Leu Met Ser Gly Ala Leu Gly Leu Val 405 410 415 Gly Gly Val Pro Gly Leu Val Met Leu Gly Ala Ala Ala Trp Tyr Thr 420 425 430 Leu Tyr Gln Asn Gln Glu Gln Ala Arg Glu Ser Ala Arg Gln Tyr Ala 435 440 445 Leu Thr Ile Asp Glu Ile Ala His Lys Thr Pro Ser Met Ser Leu Pro 450 455 460 Glu Ala Ser Asp Asn Glu Gly Arg Thr Arg Ala Ala Leu Thr Glu Gln 465 470 475 480 Asn Arg Leu Ile Asp Glu Gln Ala Ser Arg Val Lys Ser Leu Gln Glu 485 490 495 Lys Ala Gln Ser Ile Gln Asp Val Leu Ala Gly Leu Glu Asp Arg Arg 500 505 510 Val Ala Leu Ile Arg Gln Gln Ala Ala Glu Gln Asn Lys Val Tyr Gln 515 520 525 Ser Met Leu Val Met Asn Gly Gln His Thr Glu Phe Asn Arg Leu Leu 530 535 540 Gly Leu Gly Asn Glu Leu Leu Gln Gln Arg Gln Gly Leu Val Asn Val 545 550 555 560 Pro Leu Arg Leu Pro Gln Ala Thr Leu Asp Asp Lys Gln Gln Ser Ala 565 570 575 Leu Thr Lys Thr Glu Arg Glu Leu Ala Leu Ser Arg Leu Lys Gly Glu 580 585 590 Glu Lys Glu Arg Ala Arg Leu Gly Tyr Ala Ala Asp Asp Leu Gly Phe 595 600 605 Val Gly Asp Ser Tyr Gln Glu Ala Arg Gln Arg Tyr Ile Ser Asn Ala 610 615 620 Leu Glu Ala Trp Arg Asn Asn Glu Ala Asn Lys Pro Lys Ser Arg Gly 625 630 635 640 Gly Lys Ser Glu Thr Glu Lys Ala Glu Asp Ser Phe Ser Arg Leu Leu 645 650 655 Lys Gln Gln Lys Ala Gln Leu Ala Leu Ala Gly Gln Asn Thr Glu Leu 660 665 670 Ala Lys Leu Lys Tyr Gln Thr Ala Gln Gly Glu Leu Lys Thr Leu Thr 675 680 685 Glu Ile Gln Lys Gln Glu Leu Leu Arg Asn Ala Ala Leu Ile Asp Gln 690 695 700 Gln Lys Ile Arg Glu Gln Leu Arg Ser Arg Glu Glu Thr Leu Lys Asn 705 710 715 720 Glu Asn Ala Ala Ala Arg Ala Ser Asn Asp Ala Glu Leu Leu Gly Tyr 725 730 735 Gly Gln Gly Glu Arg Ala Arg Glu Arg Met Arg Glu Leu Gln Gln Ile 740 745 750 Arg Asp Ser Phe Arg Gln Lys Asp Ala Asp Leu Gln Ser Gln Tyr Gln 755 760 765 Thr Gly Asp Ile Ser Glu Asp Phe Tyr Arg Gln Ala Leu Ala Gln Asn 770 775 780 Ala Gln Tyr Leu Ser Glu Arg Leu Lys Asp Gln Glu Thr Phe Tyr Ala 785 790 795 800 Glu Ser Asp Ala Gln Arg Ala Asp Trp Gln Lys Gly Leu Gln Glu Gly 805 810 815 Phe Ser Asn Trp Val Asp Asn Ala Ser Asp Tyr Ala Ser Gln Ala Ala 820 825 830 Gln Leu Ala Thr Glu Gly Ile Ser Gly Met Val Asn Asn Ile Thr Glu 835 840 845 Met Leu Asn Gly Asn Lys Val Glu Trp Arg Ser Trp Ala Ser Ser Val 850 855 860 Leu Gln Glu Ile Ser Lys Val Leu Met Asn Ala Ala Ile Val Asn Gly 865 870 875 880 Ile Lys Thr Ala Ala Asn Gly Met Ser Gly Ala Gly Gly Phe Leu Gly 885 890 895 Ser Ile Gly Asp Trp Leu Gly Gly Ala Val Ala Asn Ala Lys Gly Gly 900 905 910 Val Tyr Thr Ser Ala Asn Leu Ser Ala Tyr Ser Asn Ser Ile Val Asp 915 920 925 Thr Pro Thr Tyr Phe Ala Phe Ala Lys Gly Ala Gly Leu Met Gly Glu 930 935 940 Ala Gly Pro Glu Ala Ile Met Pro Leu Thr Arg Ala Ala Asp Gly Ser 945 950 955 960 Leu Gly Val Arg Ala Val Gly Ser Met Asn Gly Ser Ala Gly Leu Val 965 970 975 Tyr Ser Pro Val Tyr His Ile Ala Ile Gln Asn Asp Gly Thr Asn Gly 980 985 990 Gln Ile Gly Pro Glu Ala Ala Gly Ser Leu Val Gln Leu Ile Asp Gln 995 1000 1005 Arg Val Gln Ala Val Met Leu Ser Met Arg Arg Asp Gly Gly Met Leu 1010 1015 1020 Ser Gly * 1025 <210> 914 <211> 114 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28495..28836) <400> 914 Val Ala Glu Ile Lys Thr Leu His Leu Val Pro Arg Glu Gly Met Gln 1 5 10 15 Val Ser Glu Lys Pro Ser Val Val Arg Val Arg Phe Gly Asp Gly Tyr 20 25 30 Glu Gln Arg Arg Pro Thr Gly Leu Asn Pro Gln Leu Lys Thr Phe Gln 35 40 45 Ala Val Phe Arg Val Thr Asp Glu Ser Thr Arg Arg Trp Leu Glu Glu 50 55 60 Phe Leu Ser Trp His Gly Gly Tyr Arg Ala Phe Leu Trp Arg Pro Pro 65 70 75 80 Lys His Asn Arg Thr Val Arg Val Val Cys Arg Glu Trp Ser Val Thr 85 90 95 Asp Asn Ala Arg Tyr Ser Asp Phe Ser Cys Thr Ile Glu Gln Val Val 100 105 110 Asn * <210> 915 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28836..29534) <400> 915 Met Gln Asp Ile His Glu Glu Ser Leu Asn Glu Ser Val Lys Ser Glu 1 5 10 15 Gln Ser Pro Arg Val Val Leu Trp Glu Ile Asp Leu Thr Val Gln Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Leu Asn Glu Lys Gly Glu Ala 35 40 45 Val Thr Trp Gln Gly Arg Gln Tyr Gln Ala Tyr Pro Ile Asp Gly Ser 50 55 60 Gly Phe Glu Met Asn Gly Lys Gly Ser Ser Ala Arg Pro Ser Leu Thr 65 70 75 80 Val Ser Asn Leu Phe Gly Leu Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Ala Thr Val Val Arg Arg Arg Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Ala Gly Asn Pro Glu Ala Asp Pro Glu 115 120 125 Gln Glu Leu Ser Asp Arg Trp Val Val Glu Gln Met Ser Gln Leu Thr 130 135 140 Ala Met Thr Ala Ser Phe Val Leu Ala Thr Pro Thr Glu Thr Asp Gly 145 150 155 160 Ala Leu Phe Pro Gly Arg Ile Met Leu Ala Asn Thr Cys Met Trp Thr 165 170 175 Tyr Arg Ser Asp Glu Cys Gly Tyr Thr Gly Gly Ala Val Ala Asp Glu 180 185 190 Phe Asp Asn Pro Thr Thr Asp Ile Arg Lys Asp Arg Cys Ser Lys Cys 195 200 205 Met Arg Gly Cys Glu Met Arg Gly Met Ala Val Asn Phe Gly Gly Phe 210 215 220 Leu Ser Ile Asn Lys Leu Ser Gln * 225 230 <210> 916 <211> 248 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29545..30288) <400> 916 Met Thr Gln Thr Glu Ser Ala Ile Leu Ala His Ala Arg Arg Cys Ala 1 5 10 15 Pro Ala Glu Ser Cys Gly Phe Val Val Arg Thr Pro Glu Gly Glu Arg 20 25 30 Tyr Ile Pro Cys Val Asn Ile Ser Ala Glu Pro Glu Ala Tyr Phe Arg 35 40 45 Ile Ala Pro Glu Asp Trp Leu Arg Ala Glu Met Gln Gly Glu Ile Val 50 55 60 Ala Leu Val His Ser His Pro Gly Gly Leu Pro Trp Leu Ser Glu Ala 65 70 75 80 Asp Arg Arg Leu Gln Ile Lys Ser Ala Leu Ser Trp Trp Leu Val Cys 85 90 95 Arg Gly Glu Ile His Lys Phe Arg Cys Val Pro His Leu Thr Gly Arg 100 105 110 Arg Phe Glu His Gly Val Thr Asp Cys Tyr Thr Leu Phe Arg Asp Ala 115 120 125 Tyr His Leu Ala Gly Ile Asp Met Pro Asp Phe Glu Arg Glu Asp Asp 130 135 140 Trp Trp Arg Asn Gly Gln Asn Leu Tyr Leu Asp Asn Met Glu Ala Thr 145 150 155 160 Gly Phe Tyr Arg Ile Ser Leu Pro Ser Ala Gln Pro Gly Asp Ile Leu 165 170 175 Leu Cys Cys Phe Gly Ala Ser Val Pro Asn His Ala Ala Ile Tyr Cys 180 185 190 Gly Asn Gly Glu Leu Leu His His Leu Pro Glu Gln Leu Ser Lys Arg 195 200 205 Glu Arg Tyr Ser Glu Lys Trp Gln Arg Arg Thr His Ser Ala Trp Arg 210 215 220 His Arg His Trp His Ala Ser Ala Phe Thr Gly Ile Tyr Asn Asp Leu 225 230 235 240 Ala Ala Ala Ser Ala Cys Met * 245 <210> 917 <211> 227 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30186..30866) <400> 917 Met Ala Thr Thr Asn Ala Phe Ser Leu Ala Ser Pro Pro Leu Ala Arg 1 5 10 15 Ile Cys Leu His Gly Asp Leu Gln Arg Phe Gly Arg Arg Leu Ser Leu 20 25 30 Tyr Val Asn Thr Ala Ala Glu Ala Ile Arg Ala Leu Ser Leu Gln Val 35 40 45 Pro Gly Phe Arg Arg Gln Met Asn Glu Gly Trp Tyr Gln Ile Arg Ile 50 55 60 Ala Gly Asp Asp Thr Ala Pro Glu Ala Val Tyr Ala Arg Leu His Glu 65 70 75 80 Gln Leu Gly Glu Gly Thr Val Ile His Ile Val Pro Arg Leu Ala Gly 85 90 95 Ala Gly Lys Gly Gly Leu Gln Ile Val Leu Gly Ala Ala Ala Ile Val 100 105 110 Gly Ser Phe Phe Thr Ala Gly Ala Ser Met Ala Ala Trp Gly Ala Ala 115 120 125 Leu Ser Ala Gly Gly Phe Ser Ala Thr Thr Met Leu Phe Ser Leu Gly 130 135 140 Ala Ser Met Ile Leu Gly Gly Val Ala Gln Met Leu Ala Pro Lys Pro 145 150 155 160 Lys Thr Pro Glu Tyr Arg Ala Thr Asp Asn Gly Lys Gln Asn Thr Tyr 165 170 175 Phe Ser Ser Leu Asp Asn Met Ile Ala Gln Gly Asn Pro Met Pro Val 180 185 190 Pro Tyr Gly Glu Met Leu Val Gly Ser Arg Arg Ile Ser Gln Asp Ile 195 200 205 Ser Thr Arg Asp Glu Gly Gly Gly Gly Lys Val Val Val Ile Gly Arg 210 215 220 Gln Ala * 225 <210> 918 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30820..31026) <400> 918 Met Lys Ala Gly Ala Glu Arg Ser Trp Leu Ser Gly Gly Arg His Lys 1 5 10 15 Ser Glu Lys Ile Pro Gln Cys Ser Arg Thr Gly Thr Ala Gly Ala Leu 20 25 30 Arg Arg Leu Ser Val Arg Asn Tyr Ser Tyr Val Thr Thr Lys Thr Leu 35 40 45 Thr Gln Arg Gly Arg Met Cys Arg Ser Phe Gln Gly Glu Arg Ile Tyr 50 55 60 Arg Pro Glu Glu * 65 <210> 919 <211> 176 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31057..31584) <400> 919 Met Lys Cys Lys Ile Ile Ala Ala Ile Ala Met Leu Thr Ala Ala Ser 1 5 10 15 Cys Gly Tyr Ala Ala Glu Gln Glu Val Pro Met Asn Leu Val Ser Ala 20 25 30 Asp Gly Lys Glu Val Ser Ile Gly Lys Ile Thr Ile Gln Glu Thr Pro 35 40 45 Tyr Gly Leu Leu Phe Thr Pro Ala Leu His Ser Leu Ser Glu Gly Ile 50 55 60 His Gly Phe His Val His Glu Lys Gly Asn Cys Ala Pro Ala Leu Lys 65 70 75 80 Asp Gly Lys Pro Val Ala Ala Leu Ser Ala Gly Gly His Phe Asp Pro 85 90 95 Lys Asn Thr Gly Lys His Leu Gly Pro Trp Ser Pro Asp Gly His Leu 100 105 110 Gly Asp Leu Pro Ala Leu Phe Val Thr His Asp Gly Lys Ala Asn Tyr 115 120 125 Pro Val Leu Ala Pro Arg Leu Asn Ser Leu Lys Glu Ile Lys Gly Arg 130 135 140 Ser Leu Met Leu His Ala Gly Gly Asp Asn His His Asp His Pro Glu 145 150 155 160 Pro Leu Gly Gly Gly Gly Ala Arg Met Ala Cys Gly Ile Ile Gln * 165 170 175 <210> 920 <211> 1166 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31718..35215) <400> 920 Met Gly Lys Gly Gly Gly Arg Ala His Thr Pro Arg Glu Ala Lys Asp 1 5 10 15 Asn Leu Lys Ser Thr Gln Met Met Ser Val Ile Asp Ala Ile Gly Glu 20 25 30 Gly Pro Ile Glu Gly Pro Val Lys Gly Leu Gln Ser Ile Leu Val Asn 35 40 45 Lys Thr Pro Leu Thr Asp Thr Asp Gly Asn Pro Val Ile His Gly Val 50 55 60 Thr Ala Val Trp Arg Ala Gly Glu Gln Glu Gln Thr Pro Pro Glu Gly 65 70 75 80 Phe Glu Ser Ser Gly Ala Glu Thr Gly Leu Gly Val Glu Val Thr Lys 85 90 95 Ala Lys Pro Val Thr Arg Thr Ile Thr Ser Ala Asn Ile Asp Arg Leu 100 105 110 Arg Val Thr Phe Gly Val Gln Ser Leu Val Glu Thr Thr Ser Lys Gly 115 120 125 Asp Arg Asn Pro Thr Ser Val Arg Leu Leu Ile Gln Leu Glu Arg Gly 130 135 140 Gly Lys Trp Met Thr Glu Lys Asp Val Thr Ile Asn Gly Lys Thr Thr 145 150 155 160 Ser Gln Phe Leu Ala Ser Val Ile Leu Asp Asn Leu Pro Pro Arg Pro 165 170 175 Phe Asn Ile Arg Met Val Arg Glu Thr Ala Asp Ser Thr Thr Asp Gln 180 185 190 Leu Gln Asn Lys Thr Leu Trp Ser Ser Tyr Thr Glu Ile Ile Asp Val 195 200 205 Lys Gln Cys Tyr Pro Asn Thr Ala Ile Val Gly Leu Gln Val Asp Ala 210 215 220 Glu Gln Phe Gly Gly Gln Gln Met Thr Val Asn Tyr His Ile Arg Gly 225 230 235 240 Arg Ile Ile Gln Val Pro Ser Asn Tyr Asp Pro Glu Lys Arg Thr Tyr 245 250 255 Ser Gly Ile Trp Asp Gly Ser Leu Lys Pro Ala Tyr Ser Asn Asn Pro 260 265 270 Ala Trp Cys Leu Trp Asp Met Leu Thr His Pro Arg Tyr Gly Met Gly 275 280 285 Lys Arg Leu Gly Ala Ala Asp Val Asp Lys Trp Ala Leu Tyr Ala Ile 290 295 300 Ala Gln Tyr Cys Asp Gln Thr Val Pro Asp Gly Phe Gly Gly Thr Glu 305 310 315 320 Pro Arg Met Thr Phe Asn Ala Tyr Leu Ser Gln Gln Arg Lys Ala Trp 325 330 335 Asp Val Leu Ser Asp Phe Cys Ser Ala Met Arg Cys Met Pro Val Trp 340 345 350 Asn Gly Gln Thr Leu Thr Phe Val Gln Asp Arg Pro Ser Asp Val Val 355 360 365 Trp Pro Tyr Thr Asn Ser Asp Val Val Val Asp Asp Asn Gly Val Gly 370 375 380 Phe Arg Tyr Ser Phe Ser Ala Leu Lys Asp Arg His Thr Ala Val Glu 385 390 395 400 Val Asn Tyr Thr Asp Pro Gln Asn Gly Trp Gln Thr Ser Thr Glu Leu 405 410 415 Val Glu Asp Pro Glu Ala Ile Leu Arg Tyr Gly Arg Asn Leu Leu Lys 420 425 430 Met Asp Ala Phe Gly Cys Thr Ser Arg Gly Gln Ala His Arg Ala Gly 435 440 445 Leu Trp Val Ile Lys Thr Gly Leu Leu Glu Thr Gln Thr Val Asp Phe 450 455 460 Thr Leu Gly Ser Gln Gly Leu Arg His Thr Pro Gly Asp Ile Ile Glu 465 470 475 480 Ile Cys Asp Asn Asp Tyr Ala Gly Thr Met Thr Gly Gly Arg Ile Leu 485 490 495 Ser Ile Asp Ala Ala Ser Arg Thr Leu Thr Leu Asp Arg Glu Val Thr 500 505 510 Leu Pro Glu Thr Gly Ala Ala Thr Val Asn Leu Ile Asn Gly Ser Gly 515 520 525 Lys Pro Val Ser Val Ala Ile Thr Ala His Pro Ala Pro Asp Arg Ile 530 535 540 Gln Val Ser Thr Leu Pro Asp Gly Val Glu Thr Tyr Gly Val Trp Gly 545 550 555 560 Leu Ser Leu Pro Ser Leu Arg Arg Arg Leu Phe Arg Cys Val Ser Ile 565 570 575 Arg Glu Asn Thr Asp Gly Thr Phe Ala Ile Thr Ala Val Gln His Val 580 585 590 Pro Glu Lys Glu Ala Ile Val Asp Asn Gly Ala His Phe Asp Gly Asp 595 600 605 Gln Ser Gly Thr Val Asn Gly Val Thr Pro Pro Ala Val Gln His Leu 610 615 620 Thr Ala Glu Val Thr Ala Asp Ser Gly Glu Tyr Gln Val Leu Ala Arg 625 630 635 640 Trp Asp Thr Pro Lys Val Val Lys Gly Val Ser Phe Leu Leu Arg Leu 645 650 655 Thr Val Ala Ala Asp Asp Gly Ser Glu Arg Leu Val Ser Thr Ala Arg 660 665 670 Thr Thr Glu Thr Thr Tyr Arg Phe Thr Gln Leu Ala Pro Gly Asn Tyr 675 680 685 Arg Leu Thr Val Arg Ala Val Asn Ala Trp Gly Gln Gln Gly Asp Pro 690 695 700 Ala Ser Val Ser Phe Arg Ile Ala Ala Pro Ala Ala Pro Ser Arg Ile 705 710 715 720 Glu Leu Thr Pro Gly Tyr Phe Gln Ile Thr Ala Thr Pro His Leu Ala 725 730 735 Val Tyr Asp Pro Thr Val Gln Phe Glu Phe Trp Phe Ser Glu Lys Arg 740 745 750 Ile Ala Asp Ile Arg Gln Val Glu Thr Thr Ala Arg Tyr Leu Gly Thr 755 760 765 Ala Leu Tyr Trp Ile Ala Ala Ser Ile Asn Ile Lys Pro Gly His Asp 770 775 780 Tyr Tyr Phe Tyr Ile Arg Ser Val Asn Thr Val Gly Lys Ser Ala Phe 785 790 795 800 Val Glu Ala Val Gly Gln Pro Ser Asp Asp Ala Ser Gly Tyr Leu Asp 805 810 815 Phe Phe Lys Gly Glu Ile Gly Lys Thr His Leu Ala Gln Glu Leu Trp 820 825 830 Thr Gln Ile Asp Asn Gly Gln Leu Ala Pro Asp Leu Thr Glu Ile Arg 835 840 845 Thr Ser Ile Thr Asp Val Ser Asn Glu Ile Thr Gln Thr Val Asn Lys 850 855 860 Lys Leu Glu Asp Gln Ser Ala Ala Ile Gln Gln Ile Gln Lys Val Gln 865 870 875 880 Val Asp Thr Asn Asn Asn Leu Asn Ser Met Trp Ala Val Lys Leu Gln 885 890 895 Gln Met Gln Asp Gly Arg Leu Tyr Ile Ala Gly Ile Gly Ala Gly Ile 900 905 910 Glu Asn Thr Pro Asp Gly Met Gln Ser Gln Val Leu Leu Ala Ala Asp 915 920 925 Arg Ile Ala Met Ile Asn Pro Ala Asn Gly Asn Thr Lys Pro Met Phe 930 935 940 Val Gly Gln Gly Asp Gln Ile Phe Met Asn Glu Val Phe Leu Lys Tyr 945 950 955 960 Leu Thr Ala Pro Thr Ile Thr Ser Gly Gly Asn Pro Pro Ala Phe Ser 965 970 975 Leu Thr Pro Asp Gly Arg Leu Thr Ala Lys Asn Ala Asp Ile Ser Gly 980 985 990 Ser Val Asn Ala Asn Ser Gly Ala Leu Asn Asn Val Thr Ile Asn Gln 995 1000 1005 Asn Cys Thr Ile Lys Gly Met Leu Glu Ala Thr Gln Val Arg Gly Asp 1010 1015 1020 Phe Val Lys Ala Val Ser Lys Ala Phe Pro Lys Lys Val Gly Thr Trp 1025 1030 1035 1040 Gly Asn Thr Glu Thr Pro Asn Gly Thr Val Thr Val Thr Ile Ser Asp 1045 1050 1055 Asp His Asn Phe Asp Arg Gln Ile Ile Ile Pro Pro Ile Ile Phe Asn 1060 1065 1070 Gly Ile Ala Tyr Asp Asp Pro Gly Ser Gly Asn Asn Pro Gly Gly Thr 1075 1080 1085 Arg Tyr Thr Gly Tyr Gly Phe Glu Val Arg Lys Asn Gly Val Leu Ile 1090 1095 1100 Ala Ser Arg Glu Thr Lys Gly Ala Ile Pro Gly Ser Tyr Ser Ala Val 1105 1110 1115 1120 Ile Asp Met Pro Ser Gly Gly Gly Ser Val Thr Leu Glu Phe Lys Ile 1125 1130 1135 Phe Gln Lys Gly Asn Gln Gly Ala Gly Asn Ile Thr Asp Cys Thr Val 1140 1145 1150 Ile Val Thr Lys Lys Ala Ala Ser Gly Ile Ser Ile Arg * 1155 1160 1165 <210> 921 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(35286..35885) <400> 921 Met Arg Lys Leu Tyr Ala Ala Ile Leu Ser Ala Ala Ile Cys Leu Thr 1 5 10 15 Val Ser Gly Ala Pro Ala Trp Ala Ser Glu Gln Gln Ala Thr Leu Ser 20 25 30 Ala Gly Tyr Leu His Val Ser Thr Asn Ala Pro Gly Ser Asp Asn Leu 35 40 45 Asn Gly Ile Asn Val Lys Tyr Arg Tyr Glu Phe Thr Asp Thr Leu Gly 50 55 60 Leu Val Thr Ser Phe Ser Tyr Ala Gly Asp Arg Asn Arg Gln Ile Thr 65 70 75 80 Arg Tyr Ser Asp Thr Arg Trp His Glu Asp Ser Val Arg Asn Arg Trp 85 90 95 Phe Ser Val Met Ala Gly Pro Ser Val Arg Val Asn Glu Trp Phe Ser 100 105 110 Ala Tyr Ala Met Ala Gly Val Ala Tyr Ser Arg Val Ser Thr Phe Ser 115 120 125 Gly Asp Tyr Leu Arg Val Thr Asp Asn Lys Gly Lys Thr His Asp Val 130 135 140 Leu Thr Gly Ser Asp Asp Gly Arg His Ser Asn Thr Ser Leu Ala Trp 145 150 155 160 Gly Ala Gly Val Gln Phe Asn Pro Thr Glu Ser Val Ala Ile Asp Ile 165 170 175 Ala Tyr Glu Gly Ser Gly Ser Gly Asp Trp Arg Thr Asp Gly Phe Ile 180 185 190 Val Gly Val Gly Tyr Lys Phe * 195 <210> 922 <211> 362 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36178..37263) <400> 922 Val Tyr Glu Asp Ser Gln Pro Gly Thr Leu Asn Asp Phe Leu Gly Ala 1 5 10 15 Met Ser Glu Asp Asp Val Arg Pro Glu Ala Leu Arg Arg Phe Glu Leu 20 25 30 Met Val Glu Glu Ala Ala Arg His Ala Glu Glu Ala Lys Lys Asn Ala 35 40 45 Gly Glu Ala Glu Thr Ser Ala Arg Asn Ala Gly Ile Ser Ala Ser Gln 50 55 60 Ala Glu Glu Ser Ala Ala Asn Ala Asp Thr Ser Ala Gly Asp Ala Ser 65 70 75 80 Glu Ser Ala Arg Gln Ala Ala Glu Ser Ala Ala Ala Ala Lys Gln Ser 85 90 95 Glu Asp Ala Ser Ser Ser Ser Ala Ser Ala Ala Ala Gln Lys Ala Ser 100 105 110 Glu Ser Ser Gln Ser Ala Ala Glu Ala Glu Leu Ser Arg Lys Thr Ala 115 120 125 Glu Ser Ala Ala Gly Asn Ala Ala Arg Asp Ala Thr Thr Ala Thr Glu 130 135 140 Lys Ala Arg Glu Ser Ala Glu Ser Ala Gln Ser Ala Glu Gln Ser Arg 145 150 155 160 Ile Ala Ala Glu Glu Ala Val Asn Arg Ile Pro Thr Val Val Gly Pro 165 170 175 Pro Gly Pro Lys Gly Glu Gln Gly Pro Ala Gly Pro Gln Gly Pro Lys 180 185 190 Gly Asp Lys Gly Glu Arg Gly Asp Thr Gly Pro Val Gly Ala Thr Gly 195 200 205 Glu Arg Gly Pro Ala Gly Asp Ala Gly Pro Ala Gly Pro Gln Gly Pro 210 215 220 Lys Gly Asp Arg Gly Glu Arg Gly Glu Thr Gly Leu Thr Gly Asn Ala 225 230 235 240 Gly Pro Gln Gly Pro Lys Gly Asp Thr Gly Ala Ala Gly Pro Ala Gly 245 250 255 Pro Gln Gly Pro Lys Gly Glu Thr Gly Ala Ala Gly Pro Val Gly Ala 260 265 270 Thr Gly Pro Gln Gly Pro Lys Gly Asp Pro Gly Glu Thr Gln Ile Arg 275 280 285 Phe Arg Leu Gly Pro Gly Asn Ile Ile Glu Thr Asn Ser Asn Gly Trp 290 295 300 Phe Pro Asp Thr Asp Gly Ala Leu Ile Thr Gly Leu Thr Phe Leu Ala 305 310 315 320 Pro Lys Asp Ala Thr Arg Val Gln Gly Phe Phe Gln His Leu Gln Val 325 330 335 Arg Phe Gly Asp Gly Pro Trp Gln Asp Val Lys Gly Leu Asp Glu Val 340 345 350 Gly Ser Asp Thr Gly Arg Thr Gly Glu * 355 360 <210> 923 <211> 114 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37193..37534) <400> 923 Val Thr Gly Arg Gly Arg Met Leu Arg Gly Trp Met Lys Trp Ala Val 1 5 10 15 Ile Gln Ala Glu Gln Glu Asn Asp Met Asn Ile Leu Arg Lys Leu Met 20 25 30 Glu Arg Leu Cys Gly Cys Gly Lys His Asp Asp Cys Glu His Gly Gln 35 40 45 Ser Leu Thr Val Gln Leu Arg Leu Gly Pro Ala Asp Ile Leu Glu Ser 50 55 60 Asp Glu Asn Gly Ile Ile Pro Glu Gln Asp Arg Val Ile Thr Gln Val 65 70 75 80 Val Ile Leu Asp Ala Asp Lys Lys Gln Ile Gln Cys Met Val Arg Pro 85 90 95 Leu Gln Ile Leu Arg Ala Asp Gly Arg Trp Glu Asn Ile Gly Gly Met 100 105 110 Lys * <210> 924 <211> 192 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37647..38222) <400> 924 Met Pro Leu Thr Ser Asp Ile Arg Ser His Ser Phe Asn Leu Gly Val 1 5 10 15 Glu Val Val Arg Ala Arg Ile Val Ala Asn Gly Arg Gly Asp Ile Thr 20 25 30 Val Gly Gly Glu Thr Val Ser Ile Val Tyr Asp Ser Thr Asn Gly Arg 35 40 45 Phe Ser Ser Ser Gly Gly Asn Gly Gly Leu Leu Ser Glu Leu Leu Leu 50 55 60 Leu Gly Phe Asn Ser Gly Pro Arg Ala Leu Gly Glu Arg Met Leu Ser 65 70 75 80 Met Leu Ser Asp Ser Gly Glu Ala Gln Ser Gln Glu Ser Ile Gln Asn 85 90 95 Lys Ile Ser Gln Cys Lys Phe Ser Val Cys Pro Glu Arg Leu Gln Cys 100 105 110 Pro Leu Glu Ala Ile Gln Cys Pro Ile Thr Leu Glu Gln Pro Glu Lys 115 120 125 Gly Ile Phe Val Lys Asn Ser Asp Gly Ser Asp Val Cys Thr Leu Phe 130 135 140 Asp Ala Ala Ala Phe Ser Arg Leu Val Gly Glu Gly Leu Pro His Pro 145 150 155 160 Leu Thr Arg Glu Pro Ile Thr Ala Ser Ile Ile Val Lys His Glu Glu 165 170 175 Cys Ile Tyr Asp Asp Thr Arg Gly Asn Phe Val Ile Lys Gly Asn * 180 185 190 <210> 925 <211> 210 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38295..38924) <400> 925 Met Pro Val Thr Thr Leu Ser Ile Pro Ser Ile Ser Gln Leu Ser Pro 1 5 10 15 Ala Gly Val Gln Ser Leu Gln Asp Ala Ala Arg Leu Glu Ser Gly Ile 20 25 30 Arg Ile Ser Ile Gly Ser Gly Gln Tyr Ser Val His Tyr Val Gln Leu 35 40 45 Leu Asp Gly Phe Ser Val Glu Pro Val Arg Gly Gly Leu Leu Asp Arg 50 55 60 Leu Leu Gly Arg Glu His Arg Met Glu Arg Arg Ala Val Ala Leu Glu 65 70 75 80 Arg Gln Leu Asn Gly Gly Val Asp Phe Leu Ser Ser Val Asn Asn Tyr 85 90 95 Phe Gln Ser Val Met Ala Glu His Arg Glu Asn Lys Thr Ser Asn Lys 100 105 110 Ile Leu Met Glu Lys Ile Asn Ser Cys Leu Phe Arg Pro Asp Ser Asn 115 120 125 His Phe Ser Cys Pro Glu Ser Phe Leu Thr Cys Pro Ile Thr Leu Asp 130 135 140 Thr Pro Glu Thr Gly Val Phe Met Arg Asn Ser Arg Gly Ala Glu Ile 145 150 155 160 Cys Ser Leu Tyr Asp Lys Asp Ala Leu Val Gln Leu Val Glu Thr Gly 165 170 175 Gly Ala His Pro Leu Ser Arg Glu Pro Ile Thr Glu Ser Met Ile Met 180 185 190 Arg Lys Asp Glu Cys His Phe Asp Thr Lys Arg Glu Ala Phe Cys Cys 195 200 205 Lys * <210> 926 <211> 214 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(39006..39647) <400> 926 Met Pro Val Asp Leu Thr Pro Tyr Ile Leu Pro Gly Val Ser Phe Leu 1 5 10 15 Ser Asp Ile Pro Gln Glu Thr Leu Ser Glu Ile Arg Asn Gln Thr Ile 20 25 30 Arg Gly Glu Ala Gln Ile Arg Leu Gly Glu Leu Met Val Ser Ile Arg 35 40 45 Pro Met Gln Val Asn Gly Tyr Phe Met Gly Ser Leu Asn Gln Asp Gly 50 55 60 Leu Ser Asn Asp Asn Ile Gln Ile Gly Leu Gln Tyr Ile Glu His Ile 65 70 75 80 Glu Arg Thr Leu Asn His Gly Ser Leu Thr Ser Arg Glu Val Thr Val 85 90 95 Leu Arg Glu Ile Glu Met Leu Glu Asn Met Asp Leu Leu Ser Asn Tyr 100 105 110 Gln Leu Glu Glu Leu Leu Asp Lys Ile Glu Val Cys Ala Phe Asn Val 115 120 125 Glu His Ala Gln Leu Gln Val Pro Glu Ser Leu Arg Thr Cys Pro Val 130 135 140 Thr Leu Cys Glu Pro Glu Asp Gly Val Phe Met Arg Asn Ser Met Asn 145 150 155 160 Ser Asn Val Cys Met Leu Tyr Asp Lys Met Ala Leu Ile His Leu Val 165 170 175 Lys Thr Arg Ala Ala His Pro Leu Ser Arg Glu Ser Ile Ala Val Ser 180 185 190 Met Ile Val Gly Arg Asp Asn Cys Ala Phe Asp Pro Asp Arg Gly Asn 195 200 205 Phe Val Leu Lys Asn * 210 <210> 927 <211> 38586 <212> DNA <213> Escherichia coli O157:H7 <400> 927 gttggcatta taaaaaagca ttgcttatca atttgttgca acgaacaggt cactatcagt 60 caaaataaaa tcattatttg atttcaattt tgtcccactc cctgcctctg tcatcacgat 120 actgtgatgc catggtgtcc gacttatgcc cgagaagatg ttgagcaaac ttatcgctta 180 tctgcttctc atagagtctt gcagacaaac tgcgcaactc gtgaaaggta ggcggatccc 240 cttcgaagga aagacctgat gcttttcgtg cgcgcataaa ataccttgat actgtgccgg 300 atgaaagcgg ttcacgacga gtagatgcaa ttatggtttc tccgccaaga atctctttgc 360 atttatcaag tgtttccttc attgatatcc cgagagcatc aacatgcaat gttgtaggga 420 tggcaatttt tacgcctgtt ttgctttgtt cgacataaag atatccatct acgatatcag 480 accacttcat ttcgcataaa tcaccaactc gctgcccggt aacaacagcc agttccattg 540 caagtctgag ccaacatggt gatgattctg ctgcttgata aattttcagg tattcgtcag 600 ccgtaagtct tgatctcctt acctctgatt ttgctgcgcg agtggcagcg accgggtttg 660 ttgttatatg gccttcagct attgcctctc ggaatgcatc gctcagtgtt gatctgatta 720 acttggctga cgccgccttg ccctcgtcta tgtatccatt gagcattgcc gcaatttctt 780 ttgtggtgat gtcttcaagt ggagcatcag gcagccccct ccttattgct ttaattttgc 840 tcatgtaatt tatgagtgtc ttctgcttga ttcctctgct ggcgaggatt ttttcgtagc 900 gatcaagcca tgaatgtaac gtaacagaat tatcactgtt gattctcgct gtcagaggct 960 tgtgtttgtg tcctgaaaat aactcaatat tggcctgtat tgcttcagtg attgctatcc 1020 tcctgtctcg gcctaaacca aactctttac ccgtccttgg gtccctgtag cagtaatatt 1080 gtttcttata taaaggttag ggggtaaatc ccggcgctca tgacttcgcc ttcttcccat 1140 ttctgatcct cttcaaaagg ctacctgtta ctggtcgatt taagtcaacc tttaccgctg 1200 attcgtggaa cagatactct cttccatcct taaccggagg agggaatatc ctgcattcgc 1260 gcacccatcg acgaactgtt tcaaggcttc ttgggcgtcg ctggcgtgcg ttccactcct 1320 gaagtgtcaa gtacatcgca aagtctccgc aattacacgc aagaaaaagc cgccatcagg 1380 cggcttggtg ttctttcagt tcttcaattc gaatattggt tatgtctgca tgtgctatct 1440 gcgcccatat catccagtgg tcatagcagt cattgatgtt ctctgcttcg ataactctgt 1500 tgaatggttc tccattccat tcacctgtga ctcggaagtg catttatcat ctccataaaa 1560 caaaacccgc cgtagcgagt tcagataaaa gaaatcctcg tcagtgcgag gatgctgttc 1620 attgctgcta tacacttttt tgctctcaac gtaagcggta gctcattctg ttgggttggt 1680 gcagttgctt ttaggaaatg ctatttaccc cttaaacgtc ggctgaaaga gctaaaatcc 1740 atgcaaaaaa tttacgcaat tttgtgtatt attgtgcagt aagtaatgag ctattttctg 1800 cgcaaaaaat ggatggtaaa tttgtccgga gcaggaaaaa ttttatgggc gctaaacatg 1860 aaaaaagatt cgtatcctta tttgatttgc atgacagttt taggcctgat ctttattttc 1920 cttttcttct ggtggcgggc agatatttac agggtcacgt ttcttaatca gagtatatcc 1980 cactattaca ttctgtttag catgggaata gcttttctgt tatctctgtt ttgggttaag 2040 aaggggatag taaaacaaag cggctggaag agtctgtcag cataccttaa ggtttatgca 2100 gggatgtgca tatttgctgg attttttctg attatacccc ttacaacact aacttatttt 2160 ttgcctggag agacatcgtc ttatgttgca ccgtatcggt atacttccgg tagttcaaaa 2220 agttgttctg gagctgaggt ggatgacccc gatctacatg agaatattcg catttgctat 2280 ccgtatggca attatgagta cgataatatt atctatgttg aaaagaaaat taatacatta 2340 ggtgcggtag taacatatgc acagaccgcg cgtgatgata ctgaatgaga tagtatatag 2400 cgggcaagtt ttagttaatt tatcgaggta atataattta cctcgactcg tttattctgg 2460 tattaatatt tcgctttacg atcgattttt atctgatgat atcatgcggt tttcatatac 2520 tgacttactg tcttttctcc gttagcgatt ttctcctgct cagcgatgat tttatctttg 2580 gcttctagtt aatttcgctc acttcgaacc tctctgttta ctgataagtt ccagatcctc 2640 ctggcaactt gcacaagtcc gacaaccctg aacggccagg cgtcttcgct catctatggg 2700 atcgccacac tcacaacaat gagtggcaga tatagcctgg tggttcaggc ggcgcatttt 2760 tattgctgtg ttgcgctgta attcttcaat ttctgatgct gaatcaatga tgtctgccat 2820 cttccattaa tccctgaatt gttggttaat acgcttgagg gtgaatgcga ataataaaaa 2880 aggagcctgt agctccctga tgattttgct tttcatgttc accgttcctt aaagacgccg 2940 tttaacatgc cgattgccag acttaagtga gtcggtgtga atcccatcag cgttaccgtt 3000 tcgcggtgct tcttcagtac gctacggcaa atgtcatcga cgtttttatc cggaaacggc 3060 tgtctggctt ttttgatttc agaattagcc tgacgggcaa tactgcgaag ggcgttttct 3120 tgctgaggtg tcattgaaca agtcccatgt cggcaagcat aagcacacag aatatgaagc 3180 ccgctgccag aaaaatgcat tcagtggttg tcataccagg tctctctcat ctgcttctgc 3240 tttcgccacc atcatttcca gcttttgcga aagggatgtg gctaacgtat gaaattcttc 3300 gtctgtttct actggtattg gcacaaacct gactccaatt tgagcaaggc tatgtgccat 3360 ctcaatactc gttcttaact caacaggaga tgctttgtgc atatcgcctc ccgtttatta 3420 tttatctcct cagccagccg ctgggctttc agcggatttc ggataacaga aaggccggga 3480 aatacccagc ctcgcttcgt aacggagtag acgaaagtga tcgtgcctac gcggatatta 3540 tcgtgaggat gcttcatcgc cattgctccc caaatacaaa accaatttca gccagtgcct 3600 cgtccatttt ttcgatgaac tccggcacca tctcgtcaaa acccgccatg tacttttcat 3660 cccgctcaac cacgacataa tgcaggcctt cacgcttcat acgcgggtca tagttggcaa 3720 agtaccaggc atcttttcgc gtcacccaca tgctgtactg cacctgggcc atgtaagccg 3780 actttatggc ctcgaaacca ccgagcctga acttcatgaa atcccgggag gtaaacgggc 3840 atttcagctc aaggccgttg ccgtcactgc ataaaccatc gggagagcag gcggtgcgca 3900 tactttcgtc gcgatagatg atcggggatt cagtaacatt cacgccggaa gtgaattcaa 3960 acagggttct ggcgtcgttc tcgtactgtt ttccccaggc cagcgcctta gcattaactt 4020 ccggagccac accggtgcaa acctcagcca gcagggtgtg gaagtaggac attttcatgt 4080 caggccactt ctttcctgag cggggctttg ctatcacgtt gtgaacttct gaagcggtga 4140 tgacgccgag ccgtaatttg tgccatgcat catccccctg ttcgacagct ctcacgtcga 4200 tcccggtacg ctgcaggata atgtccggtg tcatgctgcc accttctgct cagtggcttt 4260 ctgtttcagg aatccaagag ctttcactgc ttcggcctgt gtcagttctg acgatgcgcg 4320 aatgtcgcgg cgaaatatct gggaacagag cggcaataag tcgtcatccc atgttttatc 4380 cagggcgatt agcagagtgt taatctcctg catggtttca tcgttaaccg gagtgatgtc 4440 gcgttccggc tggcgttctg cagtgtatgc agtattttcg acaatgcgct cggcttcatc 4500 cttgtcatag ataccagcaa atccgaaggc cagacgggca cactgaatca tagctttatg 4560 ccgtaacatc cgtttgggat gcgactgcca cggccccgtg atttctctgc cttcgcgggt 4620 tttgaatggt tcgcggcggc attcatccat ccattcggta acgcagatcg gatgattacg 4680 gtccttgcgg taaatccggc atgtacagga ttcattgtcc tgctcaaagt ccatgccatc 4740 aaactgctgg ttttcattga tgatgcggga ccagccatca acgcccacca ccggaacgat 4800 gccgttctgc ttatcaggga aggcgtaaat ttctttcgtc cacggattaa ggccgtactg 4860 gttggcgacg atcaacaatg cgatgaactg cgcatcgctg gcatgaaagc gcgatgggga 4920 gacagggcgg catgagacga cagcgacgaa gtttcaccga catcatctgc gaaaactgca 4980 aataccttcc aacgaaacgc tccagaaata aacgcaagcc aatcccaaaa gaatctgacg 5040 taaaaacctt caactacacg gctcacctgt gggatatccg gtggctaaga cattgtgcga 5100 ggaaaacaag gtgattgacc aaaatcgaag ttacgaacaa gaaagcgtcg agcgggcttt 5160 aacgtgcgct aactgcggtc agaagctgca tgtgctggaa gttcacgtgt gtgagcactg 5220 ctgcgcagag ctgatgagcg attcgaatag ctcgatgcac gaggaaaaag atgatggcta 5280 aaccagcgcg aagacgatgt aaaaacgatg aatgtcggga atggtttcac cctgcattcg 5340 ctaatcagtg gtggtgctct ccagagtgtg gaaccaagat agcactcgaa cgacgaagca 5400 aagaacgcga aaaagcggaa aaggcagaaa aggcagcaga gaagaaacga cgacgagagg 5460 agcagaaaca gaaagataaa cttaagattc aaaaactcgc cttaaagccc cgcagttact 5520 ggattaaaca agcccaacaa gccgtacacg ccttcatcag agaaagagac cgcgacttac 5580 catgtatctc gtgcggaacg ctcacgtctg ctcagtggga tgccggacat taccggacaa 5640 ctgctgcggc acctcaactc cgatttgatg aacgcaatat tcacaagcaa tgcgtggtgt 5700 gcaaccagca caaaagcgga aatctcgttc cgtatcgcgt cgaactgatt agccgcatcg 5760 ggcaggaagc agtagaggaa atcgaatcaa accataaccg ctatcgctgg actgtcgaag 5820 agtgcagggc catcaaggcg gagtatcaac agaaacttaa aaaactgcga aacagcagaa 5880 gtgaggttgc atgaatatct acgaaagaat tgatggcagc aaataccgaa atatttgggt 5940 agttggcgat ctgcacggat gctacacgaa cctgatgaaa aaactggaga cgataggatt 6000 cgacaccaaa aaagacctgc ttatctcggt gggcgatttg gttgatcgcg gtacagagaa 6060 cgtagaatgc ctggaattaa tcacattccc ctggttcaga gctgtacgtg gaaaccatga 6120 gcaaatgatg attgatggct tatcagagcg tggaaacgtc aatcactggc tgcttaatgg 6180 cggtggctgg ttctttaatc tcgattacga caaagaaatt ctggctaaag ctcttgccca 6240 taaagcagat gaacttccgt taatcatcga actggtgagt aaaggaaaaa aatatgtcat 6300 ctgccacgcc gattatcctt gtgataaata cgagtttgga aagccagttg atcatcagca 6360 ggtaatctgg aaccgcgaac gaatcagcaa ctcacaagac gggatcgtga aagaaatcaa 6420 aggcgcggac acgttcatct ttggtcatac gccagcagtg aaaccactca aatttgccaa 6480 ccagatgtat atcgatactg gcgcagtgtt ctgcggaaac ctcacattga ttcaggtaca 6540 gggagaaggc gcatgagact cgaaagcgta gctaaatttc attcgccaaa aagcccgatg 6600 atgagcgact cactactggc cacagtttat tggttttcgt aactgagtca ttttattatt 6660 ttattgcaac ttttaatctt ttatagtgcg aaataaatgg agctggcatt catttcgcac 6720 tttatgtttt tgttggactt atgttatttt gattgaattc aattcagtta aaaaaagaag 6780 gtgattgctc catttataaa tgaatagtca tcccctgtct tgaattctga tgttacttta 6840 ttaaatgcta gtgtgaaggc tacaggtgca tacccaattg ttgcgccaac ttgatattca 6900 tcaacagttt tgtttagcga tactgttgtt tgtttcgtct gtattgtttt tccttcgaga 6960 gtatagttgc gattgacatc tcgtctttcc atacctgcaa aaatcttgta tttgaatccg 7020 cttgtatcgg acatatgcat taaaccacgg ggagccagca gaccaaagcc attatccgaa 7080 ttgaaggttt tatcattacc aatggcaatg gttgcgccat atgctacata ttgaaataag 7140 tttccagtaa cagcagaaac ttcagggtat aatccaacat tagcacctaa aatatccata 7200 cttggtgtca tggatagcat cccttttaca gtataaccgt agcgattctc tatttgatca 7260 tcccatgcat gatatttttc tgccccaata atctcatgag ctttattttg tactttctga 7320 ccgcctgcgt cggggccaac aacacctatg tcagtaccta atcgatagcg aatccagtca 7380 ttcgcaaggg agttccattc aataccagtg tgagtgtatg cactaaaagc tctgtctcca 7440 gttacagctg tgttgtgtct tttattactg cctgatggag agtaaatatc ttgcgcaata 7500 tggagagata attggctcga gtctgagata tcgtggctat atcccagaaa taagccttgt 7560 gagtaatcat ctctgttttc atgtttattg ccataaatat cattaagtat tggttgaaac 7620 ttccctgcat catcatttgc taatgataat gcaaggctgt tcgcgatagc tgaacacgtg 7680 gtaaatgaca gagcaataaa gacgccagcg atgacacttt ttttcatatg ttattgtctt 7740 cctttttttt gaatggtgcg cgtattttac atacatgagt ttgtaatgca aggtgcgtaa 7800 tcaatatgat gttttataat tgcgtgagac aattgattta ttcgtttttt attgcggttt 7860 ttattatctt ttaatgtaac ggtgttttta ttaagtgtgt ttgcgtggtg ttttatgttt 7920 tttataattt tattttatta aatttaaatg cattagtaat ggctattcta tatagcaata 7980 taagaactgt tacaaaaaaa gggggggcaa ttacaggtag ttatggatga tgagtgaaac 8040 agatattgga gaaccgggga atgaatgatg tctgagtctt atatatcaga actccttcgc 8100 tgtcgctggg ggctcctgtg cttatgtcgt ttccccgatt cggttttgaa cgattaccga 8160 atgttgaaga attatgccaa aatatagaaa ggatttactg catgaatacc caatatttac 8220 agtatgttcg tgagcaactt atggcagcta ctgctgactt gaacggagca acgaaaggcc 8280 agctcgaagc ctggcaggag catgcacaat ttgatactgg tacatacaaa cgaaagaagc 8340 cgcgcattct ggatgtggta actggcaaga tgattacgct ggataatacg ccgacttccg 8400 gtaagcagtc gtacgcaaaa ggttcatcca ttgctttggt cagcccggtt gaattctcaa 8460 cctcttcatg gcgccgcgcg gttttgtctc tcgatgaaca tcagaaagca tggttgcttt 8520 ggtgttacag cgaaagcgtt cgatgggggc atcaggtcac cataacgcaa tgggcatgga 8580 gcgagtttaa agatttgtta agtaacagaa aaattgcagg taagacactg gatcgcctga 8640 agacgttaat ctggctggct gcacaggatg tgaagagcga acttgcaggg cgtgaggcct 8700 atgaatacca gacactggca tcattggtgg gagtgacaac aaaaaactgg tccgagacat 8760 ttactgaacg ctgggttgca atgaagcaca tttttctaca gcttgatagt gatgctttat 8820 tgcttgtgac gagaacacgt tcaaaacaaa aggcagcatt tttacagcaa aatattgcaa 8880 aactggatta aaagccatat acttcatgca aatttggtat gttgtaaaaa atgtataaac 8940 ccgctgccga gtgggttttt ttatgccctg agttgtactt gtacggtaaa catgctggct 9000 gctatgtaat agagtttttt tagcctgtaa cctcttgacg gcattgaatt gcttttgtta 9060 tgagttgtaa gccaatgtta tcatcttgta ttggggtggt tatgaaggat ggtgcgctgc 9120 tcaggagttc ttcacttttt attgcctaca tgggatgcct tggatggggg agtgcttatt 9180 tctatggatg gggtacttct ttttactacg gcttcccatg gtggattgta ggtgcaggtg 9240 ttgatgatgt tgccagaagt ttattttttg cagttatcgt cattgctata tttcttatcg 9300 gttggggtat tggtgttgta ttctttttcg cagtgaaaag aaaacattct atgcaagagc 9360 taaatgtatt tcgcctttat tttgctgtgg aattattgtt tgtgccggca attattgagt 9420 tttctatatt gagacagaag attcaggtac ctcttttgct actgtcagca gcgattgcgc 9480 tggcggttac aatttcgata agatcttatg ggcgattttt atcggtatca tgcttctatg 9540 ataagccatt tataaaaaaa catttttttg agattgtgat gattgctttt gtggcatatt 9600 tctggctttt ttcatttctg acaggatatt acaaaccaca gtttaagaaa gaatatgaaa 9660 tgattaatta taatgatggt tggtattatg ttcttgctcg ttatgataat tgtctggttt 9720 tgtctacttc tttcaatgca ggtagtaaaa ggtttgtcat ttatcaatca gcacaagata 9780 agaatcttca ggttgatatt gtaaggacca gaatttaatt ggctgcataa ataatatttt 9840 aagttgcaag ttggctattc gtaggaatag aaccttaggc atgctgaatg cgtttcctga 9900 acattgtttt ataaactgtg tctgcttgct gttgtgatcc tgcttttagt gatggtgatg 9960 atggatttca ccagcaggat aatgttggta ctgactgatg gcgctctggt ctgcggcatt 1002 0 gtggtattgc tgtggccgat gatgaaagaa cagaatgaat aattcttgac ttttttgttt 1008 0 actgtttatt aaaaaatcaa ccgcatggtg aatcctcctt ggaggggcta aatgatcgag 1014 0 ttttaagggc acgtagcgag ttctgtttga tcattgcaga acttagcggg aggcgccatg 1020 0 cgtacatcac taatgttatt tccttctatc attttccttg tgagttctgg ctgcgcatgg 1026 0 cgcggccttt tttttatgac ctgccactgg cagatggtca tcctgtgatt tgattccggt 1032 0 tccggctttt taactctgtt cctgtacacg ggagaaattc tatgtcgatt aatcgttatg 1038 0 atattggtta caagaagtac cacgtattgt gttgagatag aaagcatggt gccagaggta 1044 0 aatgcagcag cataataaaa aagagccagc gcagaagaga acgggtaaaa gagtctgcgc 1050 0 tggcgtgggg atattccccg tggagaaatg atatgtaaca cacatcggga acctttctat 1056 0 ataaacatta tcattattgt caatcataac agtcaggtat tatgacgttt atgcatcagg 1062 0 gccatcagga attaactggt ggctttttat tgttgtcagc ttccggataa cgggagacgg 1068 0 ggtatgtacc agatggaaaa aataacaaca ggtgtgtcat acaccacgtc agcggtgggg 1074 0 acgggatact ggctactgca gttgctggac aaagtctccc catcccagtg ggtggcaata 1080 0 ggcgtattgg gtagcttggt gtttggcttg ctgacgtatc tgacaaacct ttatttcaag 1086 0 attaaagaag ataagcgtaa ggctgcgaga ggtgaataat gtcgccatca ttacgcaagg 1092 0 ctgttgctgc tgctattggt ggtggggctg ctgccatagc gtctgtgctc atcactggtc 1098 0 cgagtggtga cgatggcctg gaaggtgtca gctacatacc atacgaagat atcgttggcg 1104 0 tatggactgt atgtcacgga cacaccggaa aagacatcat tcccggtaaa acgtataccg 1110 0 aagcagaatg caaagccctc ctgaataaag accttgccac ggtcgccaga caaattaacc 1116 0 cgtacatcaa agtcgatata ccggaaacaa cgcgcggcgc tctttactcg ttcgtttaca 1122 0 acgtgggcgc tggtaatttc agaacatcga cgcttcttcg caaaataaac cagggtgata 1128 0 tcaaaggcgc atgtgatcag ctacggcgct ggacatacgc tggcggtaag caatggaaag 1134 0 ggctgatgac tcgccgcgag attgagcgtg aagtctgttt gtgggggcaa caatgagcag 1140 0 agtaaccgcg attatctccg ctctggttat ctgcatcatc gtctgccagt catgggcggt 1146 0 taatcattac cgtgataacg ccatcgccta taaagaacag cgtgataaaa aagtcagtga 1152 0 gctgaagcag gcgaccgcca ccattactga catgcagcag cgccagcgtg ctgctgatgc 1158 0 actcgatgct aaatacacga aggagttagc tgatgcgaaa gctaaaaatg atgctcttcg 1164 0 gcgcaagctt gataatggtg gtcgggtgtt cgtcaaagga aaatgccctg tgccatcctc 1170 0 agacgaaacc tccagcgcct ccggcatggg caatgatgcc accgtcgaac tctctccagt 1176 0 tgctggacga aacgttctcg gtatccggga cggaattatc cgcgaccaaa cagcactgag 1182 0 aacgcttcag gaatacatca ggacgcaatg ccttcgatga tagcgataat tttactcatc 1188 0 atccttcaca tctggctctg tagacagggt ggtgctcact tctggagtga atcatggtta 1194 0 aacatctcat tgctgatgct tgatattgag catctggcgc gcggtaaggg gctgcgttga 1200 0 gataagagcc agtcattaaa aatacctgga tttagcctcg cattcgcggg gcttttttat 1206 0 tgccattaca aaagccactc cctacagagt ggctttgata atggcttata ccctacacgg 1212 0 gataacttaa ctgatatccc ttttaacgga taaaggtatt caagcctgac acatcatgcg 1218 0 ctgtatcgtc gctgtattcc cgcattaacc atgaccgtag cccgacgggg aactccttct 1224 0 gcgcgagtgt gcgggaataa tcaaaaacga tgcacaccgg gtttttaccg cgctaatgat 1230 0 tcgcgggttt gtccctcatg ctcgccagtc ctgtgcgggg gtggaagaaa caggacactc 1236 0 acacagattc ttgtgggtcg atgctattcc tttctggatt atcccgatgc cattcatgca 1242 0 agggctgtat cagacgttcg tcatggcttt caggctgacg gctcctcccg gtggggtggc 1248 0 ctgccacggg gcgggagcgt cgcggaaaaa ggctagtttt tgcattttta tcggccacca 1254 0 tcatctttgc atcttattga ttattaatgg ttatttgttt tttgtatgtc gaattgagtg 1260 0 ttttttgttc gacatcgaac gcgttttctt aaagttgttc gcacgatgca tgtttaaagc 1266 0 tctccggagg aaatatggat catgagttga aaaacctggt gctgaatatt aatcaactgg 1272 0 cggctttatc tggtctgcac cgccagactg tcgtggcaag actgaaaaac attcgtcccg 1278 0 ctggtggaca tgacaaactc aagctatacc ggttgaccga tattctgact gaatttatgg 1284 0 ggttaccacc gccggttgct gagggcgaaa tggatccaca tgaacgcaaa gcctggtatc 1290 0 agtctgaacg tgagcgtctt aagttcgaac aggaaacggc acaactcatt ccggccagtg 1296 0 atgtcagacg ggagtttgcc atctgggcaa aagcggtcgt gcaggtgctg gagacattac 1302 0 cggatattct ggaacgtgac tgtggtctgc agcctgccgc tgtgagccgt gttcagtcca 1308 0 ttattgatga tctgcgcgat cagatagccc tgcgggtgac cgaagcaggt gcggatgatg 1314 0 aggaggaatt acagcaggag gagtaatgct gaatcaggaa accgcaaagg cagcacgaac 1320 0 cgattcaggt tatatccttc gcgcaccgag acgaatgcgg gttgctgatg ccgttgctca 1326 0 gtatatgcgg gtgcccatgg gggccgggaa ctcagtcccg tgggatccgc tggtggcacc 1332 0 gtatgttatt gagccgatga actgcctggc ctcgcgtgaa tacgacgcag tgatatttgt 1338 0 tggcccggca cgaaccggca agactatcgg cctgattgac ggctgggtga tttacaacgt 1344 0 gatttgcgat cctgcggata tgctgatcat tcagatgacg gaggaaaaag cccgcgaaca 1350 0 ctccaaaaaa cgactcgcca gaacgtttcg cgtcagcccg gaagtggtca gtcgcctgag 1356 0 tccgaacaaa aatgacaaca acgtttatga cagaacattc cttgctggca actacctgaa 1362 0 aatcggctgg ccgtcagtca atatcatgtc ctcatcagat tataaatgcg tggcgctgac 1368 0 ggattatgac cgttttccgg aagatattga tggcgagggg gatgccttct ctcttgcctc 1374 0 aaaacgtacc accacattta tgtccagtgg tatgacgctg gtggagagtt cccccggcag 1380 0 ggatgtgaag gatgtgaaat ggcgacggac ttcaccgcat gaggctccac caaccacggg 1386 0 gatactgtcg ctctataacc gtggcgatcg ccgtcgctgg tactggccct gtccacactg 1392 0 tggtgagtat tttcagccct gcggcgatgt ggttgctggt ttccgtgata ttgccgatcc 1398 0 cgtgctggca agtgaggcgg cttatattca gtgtccttcc tgttcaggac ggattatgcc 1404 0 tgaacaaaaa cgtgagctga acggacgtgg ggtctggttg cgggatggtg aatccatcaa 1410 0 tgcggatggt agtcgttatg gtgatccccg acgctcacgt attgcgtcat tctggatgga 1416 0 gggtccggca gctgcttacc agacactctc gcaactcgtt tacaaactgc ttactgcaga 1422 0 acaggaatac gagacaaccg gaagtgaaga aacactcaag acggttatca ataccgactg 1428 0 gggattacct tatcttcccc gcgccagcat ggagcaacga aaaagtgaac tgcttgagca 1434 0 gcgggcagag ccagttcctt ccagcagtgt gccggatggc gttaatttcc ttgtggcgac 1440 0 agtggatgtg caggcgggac gtcatcgccg ttttgtggtt caggtaacgg gctatggcag 1446 0 ccgtggcgaa cgctggatta ttgatcgtta caacatcacg cagtcattgc gcggtgacag 1452 0 cgacggtgag agccagcgaa ttgatccggc cagctatccg gaagactggg atgtcctgct 1458 0 gacggatgtt tttcataaaa gctggccgct ggcctccgat ccttctcaac aaatgcgact 1464 0 gatggcaatg gcggtggact ccggcggtga agacggggtc actgataatg cctataaatt 1470 0 ctggcgtcgt tgccgtcgtg atggccttgg taaacgtatt tacctgttta agggcgacag 1476 0 catccggcgc gcaaaactga tcacccgtac attccctgat aacaccggac gaacgggccg 1482 0 acgggcgcag gccgcaggtg atgtgccgct ctggcttctt cagacggatg cactgaaaga 1488 0 ccgggtgaat aacgcgttat ggcgtgactc tccaggtccc ggctatgtgc atttccctga 1494 0 ctggctgggg agctggtttt acgacgaact gacgtatgaa gagcggagta gtgacgggaa 1500 0 atggagtaag ccgggtcgcg gtgccaacga agcttttgac ctgatggtgt atgccgaggc 1506 0 tctggtcatt ctgcatggat acgaaaagat ccgctggccg gatgcaccgg ggtgggcgag 1512 0 ccgggaaacc tggctggaga gtgtcccgga cagtaccgaa ccgtcaccct caccggaacc 1518 0 ggtatccacg cctgttaaaa aacaaaaacg gaagaaaaca gtaactgacg atgttaaccc 1524 0 ctggctgact tccggaggat ggttatgaac cagaatgata tcgaagccat gattcagcgt 1530 0 tatacggaag ctgaaatggc ggtgctggac ggaaaatccg tcacctttaa tggtcagcag 1536 0 atgaccatgg aaaacttatc tgagatccgg cagggacggc aggagtggga gcgccgcctt 1542 0 gcggctctga ttacacgacg acgggggcat cccgggtacc ggctggcgag gttctgatgg 1548 0 caattcttga tgatgtgatt ggcgtttttt caccaggatg gaaagcggca aggctgcgtt 1554 0 cccgtgcggt gatccaggct tatgaggccg taaaaacgac gcggacacac aaagcccggc 1560 0 gggaaaaccg aactgccgac cagttaagcc agtacggggc cgtgtcgtta cgtgagcagg 1566 0 cccgttacct tgataacaac cacgatctgg ttattggtgt atttgacaag ctggaagaac 1572 0 gggtggtggg gaaaaacggg attattgtcg agccacatcc ggtattacgc aatggggcca 1578 0 ttgcccgtga tctggcagcg gagatacgca cccgatggag tgaatggtct gtcagtccgg 1584 0 aagtcaccgg gcagtttacc cgtccgatgc tggaacgtct gatgctgcgt acctggctgc 1590 0 gcgatggtga ggtgtttgcc cagatggttt ccgggcgcat aaacagcctg acgccttctg 1596 0 ccggtgttca tttctggctg gaggcgctcg agccagactt tattcccatg accagtgatg 1602 0 agagcaacag gctgaatcag ggcgtgtttg ttgatgactg ggggcgtccc gaaaaatatc 1608 0 tggtgtataa aagccgtccc gtatccggac ggcagatgga aaccaaagaa gtggatgcag 1614 0 agcgaatgct gcatcttaaa tttgttcgcc gtctgcacca gatgcgcggg acgtctttgt 1620 0 tgtccggtgt gctgatccgc ctcagtgccc tgaaagagta tgaggattct gagctgactg 1626 0 cagcaaggat cgccgctgct ctggggatgt acatccggaa aggcgatggg cagagctatg 1632 0 aaccggatgg taatggcagc aaggataagg aacgcgagct taccattcag ccaggcatta 1638 0 tttacgacga tctgaaaccc ggcgaagaaa tcggaatggt gaagtcggat cgccccaatc 1644 0 ctaaccttga aacttttcgt aatggtcagt tgcgtgccgt ggcggcgggc agtcgtctga 1650 0 attttttcca gtacagcgcg caactataac ggcacttaca gcgcccagcg tcaggagctg 1656 0 gttgaatcca ctgatggcta cctgatcctg caggactggt ttattggtgc cgtcacccgc 1662 0 ccgatgtatc gtgcctggct gaaacaggct gtggcatccg gtgttatcag gctaccccgc 1668 0 gatcttgacc gttcttcact gtataccgcg gtgtattccg gaccggtgat gccgtggatt 1674 0 gaccctgtta aggaggctga ggcctggaaa attcagattc gtggtggagc agcgacagaa 1680 0 tcagactggg tacgtgcagg tggtcgtaat ccggatgatg tcaaacgtcg gcgcaaggcc 1686 0 gaaattgatg aaaaccgcaa gctggatctg gtatttgata ccgatccggc cagtgataaa 1692 0 ggaggcagca gtgccgcaac gaaacgacag gagccgcagc acaccgacga ccagtccgaa 1698 0 gaataattcc tggttcagga tgcaggctgg tcaccagagt gacgcggata tttatattta 1704 0 tgacgagatt ggtttctggg gtgttacagc gaagcagttt atcagtgatc tgaatgcact 1710 0 gggcgatatc acccacatta atctcaatat caattcaccg ggtggcgatg tctttgaagg 1716 0 catcgccatt tttaatgcac tgaaaacaca tggtgcgtcc attaccgttt atgtcgacgg 1722 0 tgtggcggcg tcaatggcgt cggtcattgc gatggtggga aaaccggtca ttatgccgga 1728 0 aaactccttc atgatgattc ataaaccatt tggctttacg ggcggtgatg cggaggacat 1734 0 gcgcacctat gccgacctgc tcgataaagt tgaggcggtt ctgttacccg cttatgcaca 1740 0 gaaaaccggg aaaaccaccg atgaaattgc tgccatgctg gcggatgaga cctggatgtc 1746 0 cggtgccgaa tgtctggcac atggatttgc tgatcaggtg acgccagccg ttaaggcaat 1752 0 ggcatgtatt cagtcaaaac gtacagagga atttaaaaag atgccggaat ccattcgaaa 1758 0 catgattact ccgccacgca acagtgctcc acgcgtacag gatgatggac ctgcagcctc 1764 0 ccggacgcca gtgcaggcag cagcacctgt ggtggatgaa aacagtatcc gtgcgcaggt 1770 0 actggcagag caaaaagcgc gtgtaaacgg tattaatgat ctgtttgcca tgtttggcgg 1776 0 gcgttatcag acgctgcagg ctcagtgtct tgccgatcct gaatgttcgc tggagcaggc 1782 0 ccgcgaaaag ctgttgaacg agatggggcg cgagtccacg ccatctaata aaaatacccc 1788 0 ggctcatatt tatgccggaa acggtaattt tgtgggggat gggatccgcc aggcgctgat 1794 0 ggcgcgtgcc ggatttgaaa aaaccgaacg tgataatgtc tacaacggga tgaccctgcg 1800 0 tgaatatgcc cgtatgtcac tgactgaacg gggtattggg gtttccagtt ataacccgat 1806 0 gcagatggtc ggtgcggcgt tcacacacag tacgtctgac ttcggtaata ttctgctgga 1812 0 tgttgcgaac aaagccattc tgcagggctg ggaagatgcc cctgaaacct atgaacagtg 1818 0 gacgcggaaa ggtcagttgt ctgattttaa aattgcccat cgtgtgggta tggggggctt 1824 0 cagtgctctg cgtcaggtgc gtgaaggggc ggaatataaa tacgtcacca ccggagataa 1830 0 acaggccact attgcactgg cgacctatgg cgagctgttc agtatcaccc gtcaggccat 1836 0 tatcaatgat gatctgaata tgctgaccga tgtcccgatg aaactgggcc gtgcggcgaa 1842 0 atccactatt gccgatctgg tttatgccat tctgacgtct aacccgaaaa tctccacaga 1848 0 taatgtaagt ctgttcgata aagcgaaaca tgcaaacgta ctggagagcg ctgcaatgga 1854 0 cgtggcatcg ctggataaag cccgccagtt gatgcgcgtt cagaaagagg gggagcgtca 1860 0 tctgaatatt cgtcctgcgt tcgtactggt accgacggcg atggagtctg ttgctaacca 1866 0 ggtcattcgc tcctcaagtg tcaagggggc tgacattaac gccggtatta ttaacccggt 1872 0 gaaagatttt gcgaccgtta ttgcagagcc tcgtcttgat gataacagcc agaccacctt 1878 0 ctacctggct gcgtcaaaag gctccgatac gattgaagtg gcttatctca acggtgtgga 1884 0 tacgccatat attgatcaga tggagggctt cagtgtggat ggcgtgacaa cgaaagtgcg 1890 0 tattgacgcc ggtgtcgcgc cagttgatca ccgcggtctg gtgaaatgta cggcgtaaac 1896 0 gtcgcagaca acaactctga tggcccgtaa gggctttttt tgtacctgaa atcagcccct 1902 0 gaacggggct gtgcggagac agttatggca aagaattttg tagaagaagg aaaaacggtg 1908 0 gcgattgttg ccagtgcagc catcagcagc ggagatctgg tgcaggtggg cgatgttttt 1914 0 gcggtggcgc tgaccgatat tccacagggt gaaacaggcg acggcatgac cgaaggtgtg 1920 0 tttatgctgc ctaagctgaa aacggatgac atgaaaacgg gtaagaaggt ttatctgaag 1926 0 tcaggaaaag ttcagctgac taacagcggc tctgatccgc tggtcggggt tgtctgggca 1932 0 gatgccggaa ccagtgcaga agaagtgccg gtaaaactca atgtctgatc ccttttcccg 1938 0 gctggcagcg cgtatggatg ctatcacggt cagaaagatg ggaaagacag cctcgattaa 1944 0 tgatgtcgat atgactgtga tcccgggaga aacactggca gagctgaatg ctctgtccgg 1950 0 acctgcggtc tctctggtgg tgttttcttc gggataccgc ccacggcgcg gggatcgcgt 1956 0 tgtttatgac ggacaacaat ggacggtcac acggcatgaa cgctttaacg gtaagccaat 1962 0 gatctttatt gagtaaagag gtgtgggatg aaggggcttg agaatgccat ccgcaatctg 1968 0 aacagccttg atacccgtat ggtgccacag gccagcgcat gggcgataaa ccgtgtggca 1974 0 cagaaagcgg gctcggttgc cacccggcag gttgccggga ataccgttgc gggagataac 1980 0 caggtgaaag ggatccccct gaaactggtt cgtcagcgtg tccgggtgtt taaagccagt 1986 0 ccgtcaggaa aaatgacggc caggatccgc gttaaccggg gcaatctgcc cgccattaag 1992 0 ctggggacag cccgggtcag actggcccag cgtggtggaa aactgcagta ccgtggcagt 1998 0 gtgctgaagg tgggtaaata tcttttccgg gatgcgttta ttcagcaact ggcgaatggt 2004 0 cgctggcatg tgatgcggcg tattgatggc aaaaatcgtt accccattga tgtggtgaaa 2010 0 atcccgctgt ccggaccgct gacacaggca tttgaagatg cccgcgaccg catcattgct 2016 0 gcggaaatgc cgaaacagct ggggtatgca ctgaaacaac aactgaggtt atggctgacc 2022 0 cgatgaaccg acatacacaa atccgccagg tcgtactggc acgccttcgg gaacagtgtg 2028 0 gagacagcgc cacgtttttt gacgggcttc cggcatttgt tgatgcgcag gaactgcctg 2034 0 ccgtggcggt gtggctgagt gatgctcagt acaccggaaa aatgacggat gaagatgact 2040 0 ggcaggctgt tctgcatatt gctgtcttca tccgggcaca ggcaccggat tcagagctgg 2046 0 atatgtggat ggagagcacc attttcccgg ccctgaatga tgtatcggca ctttccggac 2052 0 tcatcgacac cctgatccca ctcggtttta actatcaacg tgataatgag atggccacct 2058 0 gggcgatggc ggaaatcacg taccagatca cgtacacgaa ttaaggaggt ggtaatgacc 2064 0 acgccaaatc cactggcaaa gacgaaaggt gcggggacga cgttctggat gtataccggc 2070 0 aacggcgatg cgtttgcgaa ccctttgtcg gacactgact ggctgcgtct tgcgatggtg 2076 0 aaggatctgc aacctggcga aatgaccgct gatgcagaag atgacactta tctcgatgat 2082 0 gaagatgcag actggaaaac gacaacccag gggcagaaat ccgttggtga tacttcggcg 2088 0 acgctggcct ggcgtccggg tgacagcggg cagaaaaaac tggttcagtt gttcgactcc 2094 0 ggtgaagtct gcgcgtttcg tatcaaatat cccaacggca ctgttgatgt tttccgcggc 2100 0 tggctgagct cactgggtaa aaccattgcc tcaaaagacg tgatgacccg cacagtgaaa 2106 0 atcagcggtg tggggcgtcc atatctggca gaggagggca ctgaaactgt gggcgttacc 2112 0 gggctgacgg tggcaccggc atccgccagt gtcaatgtgg gagcaaccac cacgctgacc 2118 0 tttacagtaa aacctgacgg agccagtgac aaagcgatca gtgtgcattc gacagatcca 2124 0 cagacagcca ctgtgaccct gaacggactt gtggccacgg tgaaaggcgt gaagcagggc 2130 0 agcgtcagca ttgtgggcat gaccgctgac gggaattttg tggctgtggc tgcggtgact 2136 0 gtcagcgctg caggttaaca ggacgatact catcatttgc cccggttatc cggggctttt 2142 0 ttgcaggtgg agaacatgat gtttctgaaa cagggcacgt ttaattatga aaagcagtcc 2148 0 gtggtgctca gtgagctgtc cgggctgcag agaattgaat atctggcgtt tgttcagcag 2154 0 cgaacggcaa agtttgatgc cgaagaggga gaactgccgg aggctgaacg acagattgct 2160 0 tttctgcgga tggggatgga tatcaatgct tggctggttt cccgctcact gtggaatgcg 2166 0 gaacagtctc aggatgttga gacgctttgc gcatccgtta ttacaacatg gtcgtatgat 2172 0 gccctgggag cgggggcgga gatggttctg tcgctgagcg gtatgggagc cattgagaat 2178 0 gccggggatt tggagcatga ggtgctgacg ccggaaaagt cctgacgcgg gaaatgcagt 2184 0 ttgtcatgcg gcttgcccgg gagttccggc gggcagactg gcggcggatg ctgtcggaaa 2190 0 tgtcggccac tgagcttggt gagtggggcg attatttccg gatgcagagc ttcagtgatg 2196 0 tgtggatgga tgcgcagttt gcctcgctga aggcattgat cgtgagaatg gtgtccggta 2202 0 gcagtgatgc tgcggtggct gatttcagcc ttttaccgga agagaacggg ataccggagc 2208 0 gaacggacga agaactgatg catcttgggg aaggtatttc cggaggtgtg cgttatggac 2214 0 cagatagcca acctggtcat tgatttgggg attgatgcgg cagagtttaa aaatgaaatt 2220 0 ccccgtatca aaaaccttct gaatggtgca gccagcgatg cagaacggtc ttctgcccgt 2226 0 atgcagcgtt ttatggagcg tcagactcag gccgcccggc agacaatgca ggcggcttct 2232 0 tcggctgcaa cagccgcatc cgtccatgcg cagacggtgg agaagagcgc acaggctcat 2238 0 gaacgcatgg cccgcgaggt ggagcaaacc cgccagcgta tggaggcact gagccagaaa 2244 0 atgcgcgagg aacaggcgca ggccatggct ctggcggagg ctcaggataa agcggctgct 2250 0 gcgttttatc gtcagattga cagtgtgaaa caggccggtg cggggctgca ggaattacag 2256 0 cgtattcagc aacagatccg acaggccaga aacagtggcg ggattggtca gcaggattat 2262 0 ctggcgctga tttctgaggt tacggcgaaa acccgtgttc ttacacaggc tgaggaagag 2268 0 gctacccgac agaaagtggc gtttatccgt cagcttaaag agcaggcaac ccgccagaat 2274 0 ctttcttctt ctgagttgct tcgtgctaag gctgcccagc tgggggtaag cagtgctgca 2280 0 gaagtgtata tccgcaaaat ggagcaggca ggaaaagcca cgcattcgct gggtctgaaa 2286 0 agtgcagcag cccgtcagga gataggcgtt ctgataggtg aactggcccg cggcaattta 2292 0 ggtgcgctga ggggatccgg aataacgctg gctaaccgtg ccgggtggat agacacactg 2298 0 atgtcaccga aaggcatgat gccaggagcg gttattggcg gtattgccgc ggctgtctat 2304 0 ggtctgggta aagcctggta tgacggtcag aaggaggggg aagaatttaa ccgccagctg 2310 0 tcgctgacgg ggcattatgc cggagtcact gccgggcagc tgtggacgct cagtcgtgct 2316 0 atttccggga atggtatcac gcaacatgct gcagccggtg cgctggctca ggtggtgggg 2322 0 agtggtgcat ttcgtggaaa cgatatcggt atggtggcga gagctgccgc acagatggag 2328 0 cgatcggttg gccagtcggt cagcgatacc ataaatcagt ttaagcggct gaaggatgat 2334 0 cctgtaaatg ccgcgaaggc tctggacaat gagctgcatt ttcttactgc cactcagctt 2340 0 gagcagatac gcgtccttgg ggagcagggg cggtccagtg atgctgcacg gatagccatg 2346 0 tctgcactgg cagaggaaac cggtcggcgt actgcggata ttgataataa cctcaatgcg 2352 0 cttggcagta cgctgaagta tctgtctgat ttgtggagtc gtttctggga tgcggccatg 2358 0 aatattggtc gtgaagactc gctggatgaa cagattgccg ctttacagga gaaagtgtcg 2364 0 cgggcgaaaa gactcccctg gacggcatca tcttctcagg ttgaatacga tcagcagcgt 2370 0 cttaacgatc ttcaggagaa aaaacgccag aaggatttgc aggatgcaaa agagcaggca 2376 0 gagcggaatt atcaggagca acagaaacgc cgtaatgctg aaaatgctgc actgaaccgg 2382 0 atgaatgaaa cggaagcagc acgacatcag cgtgaaatag cgcgtattaa tgccatgcag 2388 0 tacgccgatc aggctgtcag ggatgcggcg atacaacgtg aaaatgaacg ttacgagaaa 2394 0 gccctggcat ccggtaagaa aaaaacacgc gaaacccgta atgatgaggc cacccggtta 2400 0 ttgctgcagt acagtcagca acaggcacag gtggaaggac agattgctgc tgccagacag 2406 0 tcagcaggca ttgccacgga aaggatgaca gaagcgcgta aacagcttct ggctctgcag 2412 0 cagcgcatca gcgacctgga cgggaaaaaa ctgacggcag atgaaaagag tgtgctggcc 2418 0 cgtaaagatg aactgattca ggcactgacg ctgctggatg taaaacagca ggagcttcag 2424 0 aaacagacgg cactcaacga gctgaagaaa aaaacaattc agctgaccag tcaactggct 2430 0 gaagaagagc gcgctcagcg tcagcaacat gacctggata tcgccacggt gggtatgggt 2436 0 gatcagcagc gacagcgata tcaggtacaa ctgagtcttc gccagaaata ccagcaacag 2442 0 ctggagcagt tgaggcggga tagtgagcag aaagggacat ataacacgga tgactacaga 2448 0 aaggccgagc aggcgctgac ggagagcctg aaccgacaac tgaatgagaa tcgccgttac 2454 0 tggcaacagc ttgaagttgt acagggtaac tggaaaaacg gagtcctgcg tgcatttcag 2460 0 gattttaccg tggatgcaga taatacggca gaaacagcag aacaggtgtt ctcgtcagcc 2466 0 ttcagcaaca tgggaaatgg cctggcaact tttgtcacta ccggcaaact caatttcaaa 2472 0 tccttcacct cttctgtgct gtcagatatg gcgaaaatcc tggcgcaggc aaccatgatg 2478 0 aaatcgataa aagggattgg cagtgtactg ggatttgatc tcagcagcct ttccctgaat 2484 0 gccaatgggg ggatttatca gtctgctgat ttgagtcgtt acagtggcac ggtggttaac 2490 0 cgtccgacgt tttttgcttt tgcaaaaggc gcgggtgtga tgggggaagc gggacctgaa 2496 0 gccattctgc cattgcgtcg tggtgctgac ggtaagctgg gggttgtggc ggatattggg 2502 0 ggttcaggta tggcgatgtt ttccccgcag tacaacatcg agatcaataa cgatggcacg 2508 0 aacgggcaga taggtccggc tgccctgaag gcggtttatg acctcgggaa aaaagcggca 2514 0 gcggacttta tgcaacagca ggcccgtgat ggtggtcggt taagtggagc atatcggtaa 2520 0 tggagacgtt tcactggaaa gtgcgcccgg atatgaatgt ggtatcagag ccgaaagtgg 2526 0 tgacagtgaa gctgggcgat ggttatgaac agcgtcgtgc ggcgggactg aataaccagt 2532 0 tgtcgactta cagcgtgacg atacgtgttc gtaaatgtga acacccatct ttaaaagcct 2538 0 ttctggaacg gcacggtggc gtccgtgcat ttcagtggac gccaccttat gactggaaac 2544 0 cgatcagggt ggtttgtcgt aaatggtcgg caagcgtggg ggcgctgtgg gtaaccataa 2550 0 cggcagattt tgaacaggtc gtggcatagg aggctctgat gcaggatatt ccacaggaaa 2556 0 cacatcatga gacgacacgc ctcactcagt cagcccaggc ggtgctctgg gaaatcgatc 2562 0 tgacagaggt cggtggtgaa cgttattttt tctgtaatga gcagaacgaa aaaggtgagc 2568 0 cggttacctg gcaggggcgg cagtatcagg cataccccat tcaggggacg ggatttgaac 2574 0 tgaacggcaa gggcagttct gcccgtccga cactgacggt ttctaacctg cacggcatgg 2580 0 tcacggggat ggcggaagac ctgcagagtc tggtcggcgg aacggtggtc cggcgtaagg 2586 0 tttacgcccg ttttctggat gcggtgaact tcgtcaacgg aaacagcgac gccgatccgg 2592 0 agcaggaggt gatcagccgc tggcgcattg agcagtgcag cgaactgagc gcggtgagtg 2598 0 cctcttttgt actgtccacg ccgacggaaa cggacggcgc tgtttttccg ggacgtatca 2604 0 tgctggccaa cacctgcacc tggacctatc gcggcgatga gtgcggttat cacggtccgg 2610 0 cggtcgcgga tgaatatgac cagccaacgt ccgatatcac gaaggataaa tgcagcaaat 2616 0 gcctgagcgg ttgtaagttc cgcaataacg tcggcaactt tggcggcttc ctttccatta 2622 0 acaaactttc gcagtaaatc ccatgacaca gacagaatca gcgattctgg cgcacgcccg 2628 0 gcgatgtgcg ccagcggagt cgtgcggctt cgtggtaagc acgccggagg gggaaagata 2634 0 tttcccctgc gtgaatatct ccggtgagcc ggaggcgtat ttccgtatgt cgccggaaga 2640 0 ctggctgcag gcagaaatgc agggtgagat tgtggcgctg gtccacagcc accccggtgg 2646 0 tctgccctgg ctgagtgagg ccgaccggcg gctgcaggtg cagagtgatt tgccgtggtg 2652 0 gctggtctgc cgggggacga ttcataagtt ccgctgtgtg ccgcatctca ccgggcggcg 2658 0 ctttgagcac ggggtgacgg actgttacac gctgttccgg gatgcttatc atctggcggg 2664 0 gattgagatg ccggattttc atcgcgagga tgactggtgg cgtcacggtc agaatctcta 2670 0 tctggataat ctggaggcca cagggctgta tcaggtgccg ttgtcatcag cacaaccggg 2676 0 cgatgtgctg ctgtgctgtt ttggttcatc ggtgccgaat catgccgcca tttactgtgg 2682 0 tgatggcgag ctgctgcacc atattcctga acaactgagc aaacgagaga ggtataccga 2688 0 caaatggcag cgacgcacac actccctctg gcgtcaccgg gcatggcgcg catctgcctt 2694 0 tacggggatt tgcaacgatt tggccgccgc atcgaccttc gtgtaaaaac gggggccgaa 2700 0 gccatccggg cgctggccat gcagatcccg gcgtttcgtc agaagctgag cgacggctgg 2706 0 tatctggtac ggattgccgg gcgtgataca ggtgaaaatg aattatctgc ccgtcttaat 2712 0 gagccgctgg caaatggtgc cgtgatccac atcgtgccgc gcctggcggg tgctaaaagt 2718 0 ggcggtgtgt ttcaggcagt gctgggtgcg gcgctgattg cggtggcatg gtggaaccct 2724 0 gtgggctggc tgggggccgc ggctgtatcg ggtatgtatg cagcaggggc cagtatgatc 2730 0 ctgggtggtg tggcgcagat gctggcaccg aaagccagaa ctccccgtac acagacaacg 2736 0 gataacggca aacaaaacac ctatttctcc tcactggata acatggttgc ccagggcaat 2742 0 gttctgcccg ttctgtacgg tgaaatgcgc gtgggatcac gtgtggtttc tcaggagatc 2748 0 agcacggcag acgaagggga cggtggtcag gttgtggtga ttggtcgctg atgcaaaatg 2754 0 ttttatgtga aaccgcctcc gggcggtttt gtcgtttatg gagcatgacg aatgggtaaa 2760 0 ggaagcagta aggggcatac cccgcgcgaa gcgaaggaca acctgaagtc cacgcagctg 2766 0 ctgagtgtga tcgatgccat cagcgaagga ccgattgaag gtccggtgga tggattaaaa 2772 0 agcgtgctgc tgaacagtac gccggtgctg gacagtgaag gtaataccaa catctccggt 2778 0 gtcacggtgg tgttccgggc cggtgagcag gagcagacac cgccggaggg atttgaatcc 2784 0 tccggttctg agacggtgct gggtacggaa gtgaaatacg acacgccgat cacccgcacc 2790 0 atcacgtcgg caaacatcga tcgtctgcgc tttactttcg gtgtgcaggc actgcgggaa 2796 0 accacctcaa agggggaccg gaatccgtcg gaagtccgcc tgctggttca gatacagcgt 2802 0 aatggtggct gggtgacgga aaaagacatc accattaagg gcaaaaccac gtcgcagtat 2808 0 ctggcctcgg tggtggtgga taacctgccg ccgcgcccgt ttaatatccg gatgcgcagg 2814 0 atgacgccgg acagcaccac agaccagctg cagaacaaaa cgctctggtc gtcatacacc 2820 0 gaaatcatcg atgtgaaaca gtgctacccg aacacggcac tggttggcgt gcaggtggac 2826 0 tcggagcagt ttggcagtca gcaggtgagc cgtaattatc atcttcgcgg gcgcattctg 2832 0 caggtgccgt caaactatga tccggaaaaa cgcacttaca gcggcatctg ggacggaacg 2838 0 ttaaaaccgg catacagcaa caacatggcc tggtgtctgt gggatatgct gacccacccg 2844 0 cgctacggca tggggaaacg tcttggtgcg gcggatgtgg ataaatgggc gctgtatgtc 2850 0 atcggccagt actgcgacca gtcagtaccg gacggctttg gcggcacgga gccgcgcatc 2856 0 acctgtaatg cgtacctgac cacgcagcgc aaggcgtggg atgtgctcag tgatttctgc 2862 0 tcggcgatgc gctgtatgcc ggtatggaac gggcagacgc tgacgttcgt gcaggaccgg 2868 0 ccgtcggata aggtgtggac ctataaccgc agtaatgtgg tgatgccgga tgatggcgcg 2874 0 ccgttccgct acagctttag cgccctgaaa gaccgccata atgccgttga ggtgaactgg 2880 0 actgacccgg acaacggctg ggagacggcg acagagcttg tggaggacac gcaggccatt 2886 0 gcccgttacg gtcgtaacgt cacgaagatg gatgcctttg gctgtaccag tcgggggcag 2892 0 gcacaccgtg ccgggctgtg gctgattaaa acggaactgc tggaaacgca gaccgtggac 2898 0 ttcagcgtgg gcgcagaagg gcttcgccat gtaccgggcg atgtcattga aatctgtgat 2904 0 gatgactatg cggggatcag catcggtggg cgtgtgctgg cggtgaacag ccagacccgg 2910 0 acgctgacgc tcgaccgtga aatcacgctg ccatcctccg gcaccacgct gataagcctg 2916 0 gttgacggaa gtggcaatcc ggtcagcgtg gaggttcagt ccgtcaccga cggcgtgaag 2922 0 gtaaaagtga gccgggttcc tgacggtgtt gctgaataca gcgtgtgggg gctgaagctg 2928 0 ccgacgctgc gccagcgcct gttccgctgc gtgagtatcc gtgagaacga cgacggcacg 2934 0 tatgccatca ctgccgtgca gcatgtgccg gagaaagagg gcatcgtgga taacggggcg 2940 0 cactttgacg gtgaccagag cagcacggtg aatggtgtca cgccgccagc ggtgcagcac 2946 0 ctgaccgccg aagtctccgc agacagcggg gaatatcagg tgctggcgcg atgggacacg 2952 0 ccgaaggtgg tgaagggtgt gagcttcctg cttcgcctga ccgtggcagc ggatgacggc 2958 0 agtgagcggc tggtcagcac ggcccggacg acggaaacca cataccgctt cacgcagctg 2964 0 gcgctgggga actacaggct gacagtccgg gcggtaaatg cgtggggaca gcagggcgat 2970 0 ccggcgtcgg tatcgttccg gattgccgca ccggcagcgc cgtcacagat tgagctgaca 2976 0 ccgggctatt ttcagataac cgccacgccg catcttgcgg tttatgatcc gacggtacag 2982 0 tttgagttct ggttctcgga aacgcggatt gcggatatca ggcaggttga aaccagcgcg 2988 0 cgttatcttg gtacggcgct gtactggata gccgccagta tcaatatcaa accgggccat 2994 0 gattattact tttatatccg cagtgtgaac accgttggca aatcggcatt cgtggaggcc 3000 0 gtcggtcggg cgagcgatga tgcggaaggt tatctggatt ttttcaaagg caagataacc 3006 0 gaatctcatc tcggcaagga gctgctggaa aaagtcgatc tgacggagga taacgccagc 3012 0 agactggatg agttttcgaa agagtggaag gacgctaacg ataaatggaa tgccatgtgg 3018 0 ggcgtcaaaa ttgagcagac caaagacggc aaacattatg tcgcgggtat tggcctcagc 3024 0 atggaggaca cggaggaagg caagctgagc cagtttctgg ttgccgccaa tcgtatcgcg 3030 0 tttattgacc cggcaaacgg gaatgaaacg ccgatgtttg tggcgcaggg caaccagata 3036 0 ttcatgaacg acgtgttcct gaagcgcctg acggccccca ccattaccag cggtggaaat 3042 0 ccaccggtat tttccctgac atcagacgga aagctgaccg ctaaaaatgc ggatatcagt 3048 0 ggcagtgtga atgcgaactc cgggacgctc aacaacgtca cggtaaatga aaactgtacg 3054 0 attaagggca tgctggaggc gactcaggtc agaggtgact tcgttaaagc tgtatccaaa 3060 0 tcatttccga aacaggctgg tacgtggggt aacacggaaa caccaaacgg gacggttaca 3066 0 gtcaccatca gcgatgatca taactttgac cgtcaaatca ttattccgcc cattatcttt 3072 0 aacggaatag cgtatagcga tccgggaagt ggtaataacc cgggaggtac aagatacacg 3078 0 ggttatggtt ttgaagttcg caaaaacggt gtattaatcg catccagaga aactaaaggg 3084 0 gccattcccg gtagctacag tgcggttatt gatatgccga gtggcagggg aagcgtcact 3090 0 ctggagttta aggttttcca taaaggcaat cagcgggcag gtaatatcac cgactgtacg 3096 0 gtgattgtga ccaaaaaagc ggcttccggc atcagtatcc gttgaaatat ttataaccct 3102 0 aataacgggc gccagaaatg gcgccttttt tattgcagaa aatcgggagg taattatgcg 3108 0 taaagtttgt gcagcaattt tgtccgcagc catttgtctg gccgtatccg gtgtgcctgc 3114 0 atgggcgtct gagcatcagt ccacgctgag cgcaggatat cttcatgcca gtacggacgc 3120 0 tcccggcagc gatgatctga acgggattaa cgtgaaatac cgttatgagt ttacggacac 3126 0 actggggctg attacgtcct tcagttatgc caacgccgaa gatgagcaaa aaacgcatta 3132 0 cagcgatacc cgctggcatg aggattacgt gcgtaaccgc tggttcagcg tgatggcagg 3138 0 gccgtctgtg cgtgtgaatg aatggttcag tgcgtatgcg atggcgggtg tggcttacag 3144 0 ccgtgtgtcg actttttccg gggattattt ccgcgtaact gacaacaaga ggaaaacgca 3150 0 cgacgtgctg accggaagtg atgacgctcg ctacagcaac acatctctgg cgtggggggc 3156 0 tggcgtgcag tttaacccga ccgaatcagt ggccgttgat gtcgcttatg aaggctccgg 3162 0 cagcggtgac tggcgcactg acggtttcat cgtgggtgtc ggttataaat tttgattagt 3168 0 aacacagcgt tatgacagcc cgccggttca ggcgggcttt tttgtggagt gggtatggca 3174 0 gcagtacaaa tatcaggcgt gctgaaagat ggtgcgggaa aaccaataca gaactgcacc 3180 0 attcaactga aagccagacg taacagcacc acggtggtgg tgaacacggt ggcctctgaa 3186 0 aatccggatg aggcagggcg ttacagcatg gacgtcgagt atggtcagta cagcgtcact 3192 0 ctgttggtgg agggattccc gccatcacat gccgggacca tctccgtgta tgaagattct 3198 0 caaccgggta cgctgaatga ttttctcggt gccatgacgg aggatgatgc ccgtccggag 3204 0 gcactgcgtc gttttgaaca gatggtggaa gaagcagcgc gtcacgcaga ggaggcgaag 3210 0 aagaatgccg gagaagcaga gacgtccgcg aggaatgccg gcatatcagc cagtaaggcg 3216 0 gaagcgagcg ccgcaaatgc tgatacttca gcagaggatg catcggagtc agcccggcag 3222 0 gcggcagaaa gtgcagcctc tgcaaagaag tcagaggaag cgtcctcgtc ctcagcctct 3228 0 gaggccgctc aaaaagccag tgagtcatta caaagtgcaa cagatgccga gttgtcaaaa 3234 0 aagacggcag aaagtgcagc cggtaatgca gccagggatg caacgacctc aacagaaaaa 3240 0 gcccgggaat cagcagaaag cgcacagtca gcggaacaaa gcagaatagc ggcggaagac 3246 0 gccgtaaaca gaattcccac cgtggtgggg cctcccggac caaaggggga accgggtccc 3252 0 gcgggtcctc aggggccgaa gggagataaa ggagagcgtg gagacaccgg tccggcaggg 3258 0 gcaaccggtg aacggggacc gggaggagat acaggtccgg caggtccgca ggggccgaaa 3264 0 ggcgacaggg gagagcgggg agagaccggt ctgacaggaa gtacaggtcc acaggggcca 3270 0 aagggagata ccggggcaac aggtccggca ggaccgcagg gaccgaaagg ggaaacaggt 3276 0 gcggctggcc cggtgggggc taccggacct cagggggcga agggcgaccc gggggagaca 3282 0 caaatacggt tccgtctggg gccgatgaga attattgaga caaacagcta tggctggttc 3288 0 ccgggtacag atggtgcgct catcaccgga ctgacctttc ttgaccccaa agatgccaca 3294 0 caggttcagg ggatgtttca gcatttgcag gtcagatttg gtgacgggcc atggcaggat 3300 0 gttaagggac tggatgaagt gggcagtgat acaggcagaa ctggagaatg acatgaatat 3306 0 tttgagaaag cttatgcaga gtctgtgcgg ttgcggaaag catgatgact gtgaaaacgg 3312 0 acggtcactt acagcacaat tgcgactggg accggcagac attctggagt cagatgagaa 3318 0 tggcattatt ccggagcagg acagggtaat cacacaggtg gtgatactgg atgcagataa 3324 0 aaagcagata cagtgtgtgg taagaccgct gcaaatcctg cgtgctgacg ggacgtggga 3330 0 aaatattggc gggatgaagt aacccgacag cttcacaaaa ccggagtccg gctccggttt 3336 0 ttgttgtcat gtccggtgga tgtttgttag gaaagcaaag atggcaaaac tgctggaggt 3342 0 tttgtggttg agtatgccaa tataattaat agattaaaga gttagttgtg aagaaaatat 3348 0 ggataaacag gacgacgaat gctttcaccg ataaggacaa ctttccataa ctcagtaaat 3354 0 atagtgcaga gttcaccctg tcaaacggtt tcttttgcag gaaaggaata tgagttaaag 3360 0 gtcattgatg aaaaaacgcc tattcttttt cagtggtttg aacctaatcc tgaacgatat 3366 0 aagaaagatg aggttccaat agttaatact aagcagcatc cctatttaga taatgtcaca 3372 0 aatgcggcaa ggatagagag tgatcgtatg ataggtattt ttgttgatgg cgatttttca 3378 0 gtcaaccaaa agactgcttt ttcaaaattg gaacgagatt ttgaaaatgt aatgataatc 3384 0 tatcgggaag atgttgactt cagtatgtat gacagaaaac tatcagatat ttatcatgat 3390 0 attatatgtg aacaaaggtt acgaactgaa gacaaaagag atgaatactt gttgaatctg 3396 0 ttagagaaag agctgaggga aatttcaaag gcgcaggatt ctttgatttc tatgtatgca 3402 0 aagaaaagaa atcatgcatg gtttgatttc ttcagaaatt tagccttatt aaaagcagga 3408 0 gagatattca ggtgcacata taatacaaag aatcacggta tttcattcgg ggaggggtgt 3414 0 atctatcttg atatggatat gatacttaca ggtaagcttg gtacaatata tgctcctgat 3420 0 ggaatttcaa tgcatgtgga tcgtcgtaat gatagtgtaa atattgaaaa tagtgcaata 3426 0 attgttaacc gtagtaatca tcctgctcta cttgagggac tttcttttat gcatagtaaa 3432 0 gtagatgctc atccatatta tgatggtttg gggaaaggag ttaagaaata ttttaatttt 3438 0 acaccattac ataattataa tcatttttgt gactttattg agtttaacca ccctaatata 3444 0 atcatgaaca caagtcagta tacatgcagt tcatggtaaa tgaatttgat atagtttatt 3450 0 ttgttgtaat aaatgatttg cagggtatta gatataaaca tgaaaattcc ctcattacag 3456 0 tccaacttca acttttccgc cccggcagga tactctgctc ccattgctcc taatcgtgct 3462 0 gaaaatgcct atgcggatta cgttttggat ataggtaagc gaataccact ttccgcagca 3468 0 gatttaagca acgtatacga aagtgtaata cgcgccgtcc atgacagccg tagcaggctt 3474 0 atcgatcagc atacagtcga tatgatcggc aacactgtac ttgatgcttt gagccgatca 3480 0 cagacatttc gtgatgccgt aagctatggc attcataatg agaaggtaca cattggttgc 3486 0 attaaataca gaaacgaata cgagcttaac gaagaatctt ctgtcaaaat tgatgatatt 3492 0 caatcactaa cctgtaacga attatatgaa tatgatgtcg ggcaagagcc aattttcccc 3498 0 atttgcgaag caggagaaaa cgataacgaa gagccttatg tcagttttag tgttgcgcca 3504 0 gatactgact cttatgagat gccatcgtgg caggaaggac tgattcacga gattattcat 3510 0 catgttactg gatctagcga tccatctgga gatagtaata tagagttagg acccaccgag 3516 0 attctcgcac gtcgtgtcgc tcaagaactg ggatggagtg ttcccgactt caaaggatat 3522 0 gcagagccag aacgtgaagc tcatcttagg ctacgtaacc tgaatgccct tcgacaggct 3528 0 gccatgaggc atgaagagaa tgagagggct ttcttcgaaa ggctgggtac gatcagtgac 3534 0 cgatatgagg cgagtcctga tttcacagag tattccgctg tgtctaacat aggatacgga 3540 0 tttatccagc aacatgattt tcctggattg gctatcaacg ataatttaca ggatgcaaat 3546 0 cagatccaac tgtatcatgg cgccccttat atttttacat ttggggatgt ggacaaacac 3552 0 aatcagcaat gattcgtctt tgcagtgaca taaggttact attcatacat tttaacggag 3558 0 ttgatgatgg gtaatcgtgc aacattgtat gtaaaggcaa ttcccctaat tttactgtag 3564 0 taagtgaaca tggccggaac gagactatca gcatcatcgg cttcggccca gtaaaaagag 3570 0 gctcggaaaa atgcacaata ggcatcacac gtcatgcatg gattcaaatt gtacataatt 3576 0 caacagtaca gctataaatc gtaaagaaac tgcagtacgt tgtgcacaga aaagtaccgt 3582 0 gattcactat tgtacaggtc cattgcagca acaatatttt gtgaattttg cgtgagagaa 3588 0 agaaaaggaa taatttgtat ataaacaatt gattaatcaa ttgctggaaa ataaataaaa 3594 0 ctgataatta aaggcttaaa gcttgtatta aatcatattt aaaatttttt gttttaaatg 3600 0 cagcgtgtta ttgtgttttt tttaatctat cggtctggta cttgtaatca gtgagtatat 3606 0 cgcaccactt caggatgctg cagatttaga tattgcgacg gatgagcaga catcgttact 3612 0 ggcggcatgg aagcagtatc gtatgccgct caatcatgtt gatacgtctg tatctccaga 3618 0 tatcgagtga ccggtaatac ctgcgttata gttcgtaaac gttcgtttga tgggatgctg 3624 0 gaaggatgaa ttagttgcca gatacaaaaa gcaagagttc atttctaatt tttgttgcca 3630 0 tgttaggggg gatgtttgtt aaggaaattt agatgggttt attttgaagg ttgaaatgta 3636 0 tgttatcgcc atattctgta aatttgggat gttcatggaa ttctttaacc agaaacctga 3642 0 cttcgcctga taatcgtgtt ttatcctctg taagggatgc tgccgttcat tctgataatg 3648 0 gggcgcaagt aaaggttggc aacagaacat atcgtgttgt tgccaccgat aataagtttt 3654 0 gcgttacaag agaaagtcat agtggttgtt ttactaatct gttgcacagg ctgggatggc 3660 0 ctaaggggga gattagcagg aaaattgagg tcatgctgaa tgcatcacca gtgagcgctg 3666 0 ctatggaaag aggcattgtt cattcgaaca gacctgattt acctcctgtt gattatgcac 3672 0 cgccagagtt accgagtgtg gactataaca ggttgtcagt acctggtaat gttattggca 3678 0 aaggggggaa cgctgtagta tatgaagatg ctgaggatgc aacaaaagtc ctgaagatgt 3684 0 ttactacatc tcaaagcaat gaagaggtga caagcgaagt tcgttgcttc aaccaatatt 3690 0 atggtgccgg gagtgcagaa aaaatatatg gcaataatgg tgatattatt ggtattagaa 3696 0 tggataaaat aaatggagaa tcgcttttaa atatttcgtc cttgccagca caggctgagc 3702 0 atgctattta cgatatgttt gatagactgg agcaaaaagg aattcttttt gtcgatacaa 3708 0 cagagacaaa tgtcttatat gaccgcgcga agaatgagtt taatccaata gatatatcat 3714 0 cttataatgt ttccgaccgt tcatggagtg aaagtcaaat aatgcaatct tatcatggcg 3720 0 gaaagcaaga tcttattagt gtggtattaa gtaaaattta gtaattttat ccagtgtagt 3726 0 ggatttgttg catggatgga gttggtaaca aattgtgtgg ttggcaattc ttggcggatc 3732 0 acggaaatgg gcaatgtcgc tgaggactgg caaatggcta tgatccgctt tattatcggg 3738 0 tttggtgacc gccttgacgg tcacttttaa aaaaatcatt ttcacagagt ggtaaacagg 3744 0 ctgctaataa gtagcattct caggagtcct gatgcgccct acgtccctca acttggtatt 3750 0 acatcagtca tcaaggtcga gctcaatgtc agatacagat atcgagtctc ttgtaaaagc 3756 0 atcgagcgtt caatggataa aaaataatcc gcaacttcgt ttccagggga ctgatcataa 3762 0 tatatatcag cagattgaag cagcactcga taagattggc tctacagaga cagggcgtgt 3768 0 actcctgaat gctattgaat caatatcccg acttaaatca gaaacagtgg taatacacct 3774 0 caactcttcc agactaggag ttatggcaca tagagatata gatgctgaga accatcgggg 3780 0 gactggttcc gattttcact gtaatctgaa tgcagttgaa tatccctgtg gggaggggat 3786 0 tagcgtggtg gactttcatg cgactattgt ttttcatgag ttgctccatg ttttccacaa 3792 0 tttaaatggg gagcgtttga aagttgagag ttcccgagca gaatcacaaa aatactctcc 3798 0 acttttactc gaagaagcca ggactgttgg gttgggggct ttttcagagg aggtgctttc 3804 0 agaaaataaa ttccacgaag agattgggat gccccgtaga acctcctacc cgcacgactc 3810 0 agctcttatt catgatgaca atacagtgag tctgggattc caacaggtaa gactgcatcc 3816 0 attgctttag ctgtgtttct tgtgctgaat atatattggt ggggcaaacg gaggcacaca 3822 0 aaactttgca ctggattgca aggctttgtg ctattccgat agtggttcag gtggagtacc 3828 0 ccaccttttc atcaagccag cccacccacc actgcatcat ttctctgcgc ttatagagat 3834 0 actgagcatg gttgtaaatt cagcaaacga cgtaatgtgt ttgacaaaaa attagcgcaa 3840 0 gaagacaaaa atcaccttgc gctaatgctc tgttacaggt cactaatacc atctaagtag 3846 0 ttgattcata gtgactggat atgttgtgtt ttgtagcatt atgcagtcta ttttttagac 3852 0 taaatgcatt gtaatacatt gatattattg ggttttgctg tttcgcgttc agctttttta 3858 0 tactaa 3858 6 <210> 928 <211> 73 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1118..1336) <400> 928 Met Tyr Leu Thr Leu Gln Glu Trp Asn Ala Arg Gln Arg Arg Pro Arg 1 5 10 15 Ser Leu Glu Thr Val Arg Arg Trp Val Arg Glu Cys Arg Ile Phe Pro 20 25 30 Pro Pro Val Lys Asp Gly Arg Glu Tyr Leu Phe His Glu Ser Ala Val 35 40 45 Lys Val Asp Leu Asn Arg Pro Val Thr Gly Ser Leu Leu Lys Arg Ile 50 55 60 Arg Asn Gly Lys Lys Ala Lys Ser * 65 70 <210> 929 <211> 56 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1376..1543) <400> 929 Met His Phe Arg Val Thr Gly Glu Trp Asn Gly Glu Pro Phe Asn Arg 1 5 10 15 Val Ile Glu Ala Glu Asn Ile Asn Asp Cys Tyr Asp His Trp Met Ile 20 25 30 Trp Ala Gln Ile Ala His Ala Asp Ile Thr Asn Ile Arg Ile Glu Glu 35 40 45 Leu Lys Glu His Gln Ala Ala * 50 55 <210> 930 <211> 41 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1845..1967) <400> 930 Met Gly Ala Lys His Glu Lys Arg Phe Val Ser Leu Phe Asp Leu His 1 5 10 15 Asp Ser Phe Arg Pro Asp Leu Tyr Phe Pro Phe Leu Leu Val Ala Gly 20 25 30 Arg Tyr Leu Gln Gly His Val Ser * 35 40 <210> 931 <211> 177 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1858..2388) <400> 931 Met Lys Lys Asp Ser Tyr Pro Tyr Leu Ile Cys Met Thr Val Leu Gly 1 5 10 15 Leu Ile Phe Ile Phe Leu Phe Phe Trp Trp Arg Ala Asp Ile Tyr Arg 20 25 30 Val Thr Phe Leu Asn Gln Ser Ile Ser His Tyr Tyr Ile Leu Phe Ser 35 40 45 Met Gly Ile Ala Phe Leu Leu Ser Leu Phe Trp Val Lys Lys Gly Ile 50 55 60 Val Lys Gln Ser Gly Trp Lys Ser Leu Ser Ala Tyr Leu Lys Val Tyr 65 70 75 80 Ala Gly Met Cys Ile Phe Ala Gly Phe Phe Leu Ile Ile Pro Leu Thr 85 90 95 Thr Leu Thr Tyr Phe Leu Pro Gly Glu Thr Ser Ser Tyr Val Ala Pro 100 105 110 Tyr Arg Tyr Thr Ser Gly Ser Ser Lys Ser Cys Ser Gly Ala Glu Val 115 120 125 Asp Asp Pro Asp Leu His Glu Asn Ile Arg Ile Cys Tyr Pro Tyr Gly 130 135 140 Asn Tyr Glu Tyr Asp Asn Ile Ile Tyr Val Glu Lys Lys Ile Asn Thr 145 150 155 160 Leu Gly Ala Val Val Thr Tyr Ala Gln Thr Ala Arg Asp Asp Thr Glu 165 170 175 * <210> 932 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2599..2820) <400> 932 Met Ala Asp Ile Ile Asp Ser Ala Ser Glu Ile Glu Glu Leu Gln Arg 1 5 10 15 Asn Thr Ala Ile Lys Met Arg Arg Leu Asn His Gln Ala Ile Ser Ala 20 25 30 Thr His Cys Cys Glu Cys Gly Asp Pro Ile Asp Glu Arg Arg Arg Leu 35 40 45 Ala Val Gln Gly Cys Arg Thr Cys Ala Ser Cys Gln Glu Asp Leu Glu 50 55 60 Leu Ile Ser Lys Gln Arg Gly Ser Lys * 65 70 <210> 933 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2919..3200) <400> 933 Met His Phe Ser Gly Ser Gly Leu His Ile Leu Cys Ala Tyr Ala Cys 1 5 10 15 Arg His Gly Thr Cys Ser Met Thr Pro Gln Gln Glu Asn Ala Leu Arg 20 25 30 Ser Ile Ala Arg Gln Ala Asn Ser Glu Ile Lys Lys Ala Arg Gln Pro 35 40 45 Phe Pro Asp Lys Asn Val Asp Asp Ile Cys Arg Ser Val Leu Lys Lys 50 55 60 His Arg Glu Thr Val Thr Leu Met Gly Phe Thr Pro Thr His Leu Ser 65 70 75 80 Leu Ala Ile Gly Met Leu Asn Gly Val Phe Lys Glu Arg * 85 90 <210> 934 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3211..3402) <400> 934 Met His Lys Ala Ser Pro Val Glu Leu Arg Thr Ser Ile Glu Met Ala 1 5 10 15 His Ser Leu Ala Gln Ile Gly Val Arg Phe Val Pro Ile Pro Val Glu 20 25 30 Thr Asp Glu Glu Phe His Thr Leu Ala Thr Ser Leu Ser Gln Lys Leu 35 40 45 Glu Met Met Val Ala Lys Ala Glu Ala Asp Glu Arg Asp Leu Val * 50 55 60 <210> 935 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3375..3557) <400> 935 Met Lys His Pro His Asp Asn Ile Arg Val Gly Thr Ile Thr Phe Val 1 5 10 15 Tyr Ser Val Thr Lys Arg Gly Trp Val Phe Pro Gly Leu Ser Val Ile 20 25 30 Arg Asn Pro Leu Lys Ala Gln Arg Leu Ala Glu Glu Ile Asn Asn Lys 35 40 45 Arg Glu Ala Ile Cys Thr Lys His Leu Leu Leu Ser * 50 55 60 <210> 936 <211> 227 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3554..4234) <400> 936 Met Thr Pro Asp Ile Ile Leu Gln Arg Thr Gly Ile Asp Val Arg Ala 1 5 10 15 Val Glu Gln Gly Asp Asp Ala Trp His Lys Leu Arg Leu Gly Val Ile 20 25 30 Thr Ala Ser Glu Val His Asn Val Ile Ala Lys Pro Arg Ser Gly Lys 35 40 45 Lys Trp Pro Asp Met Lys Met Ser Tyr Phe His Thr Leu Leu Ala Glu 50 55 60 Val Cys Thr Gly Val Ala Pro Glu Val Asn Ala Lys Ala Leu Ala Trp 65 70 75 80 Gly Lys Gln Tyr Glu Asn Asp Ala Arg Thr Leu Phe Glu Phe Thr Ser 85 90 95 Gly Val Asn Val Thr Glu Ser Pro Ile Ile Tyr Arg Asp Glu Ser Met 100 105 110 Arg Thr Ala Cys Ser Pro Asp Gly Leu Cys Ser Asp Gly Asn Gly Leu 115 120 125 Glu Leu Lys Cys Pro Phe Thr Ser Arg Asp Phe Met Lys Phe Arg Leu 130 135 140 Gly Gly Phe Glu Ala Ile Lys Ser Ala Tyr Met Ala Gln Val Gln Tyr 145 150 155 160 Ser Met Trp Val Thr Arg Lys Asp Ala Trp Tyr Phe Ala Asn Tyr Asp 165 170 175 Pro Arg Met Lys Arg Glu Gly Leu His Tyr Val Val Val Glu Arg Asp 180 185 190 Glu Lys Tyr Met Ala Gly Phe Asp Glu Met Val Pro Glu Phe Ile Glu 195 200 205 Lys Met Asp Glu Ala Leu Ala Glu Ile Gly Phe Val Phe Gly Glu Gln 210 215 220 Trp Arg * 225 <210> 937 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4932..5114) <400> 937 Met Arg Arg Gln Arg Arg Ser Phe Thr Asp Ile Ile Cys Glu Asn Cys 1 5 10 15 Lys Tyr Leu Pro Thr Lys Arg Ser Arg Asn Lys Arg Lys Pro Ile Pro 20 25 30 Lys Glu Ser Asp Val Lys Thr Phe Asn Tyr Thr Ala His Leu Trp Asp 35 40 45 Ile Arg Trp Leu Arg His Cys Ala Arg Lys Thr Arg * 50 55 60 <210> 938 <211> 57 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5111..5281) <400> 938 Val Ile Asp Gln Asn Arg Ser Tyr Glu Gln Glu Ser Val Glu Arg Ala 1 5 10 15 Leu Thr Cys Ala Asn Cys Gly Gln Lys Leu His Val Leu Glu Val His 20 25 30 Val Cys Glu His Cys Cys Ala Glu Leu Met Ser Asp Ser Asn Ser Ser 35 40 45 Met His Glu Glu Lys Asp Asp Gly * 50 55 <210> 939 <211> 208 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5271..5894) <400> 939 Met Met Ala Lys Pro Ala Arg Arg Arg Cys Lys Asn Asp Glu Cys Arg 1 5 10 15 Glu Trp Phe His Pro Ala Phe Ala Asn Gln Trp Trp Cys Ser Pro Glu 20 25 30 Cys Gly Thr Lys Ile Ala Leu Glu Arg Arg Ser Lys Glu Arg Glu Lys 35 40 45 Ala Glu Lys Ala Glu Lys Ala Ala Glu Lys Lys Arg Arg Arg Glu Glu 50 55 60 Gln Lys Gln Lys Asp Lys Leu Lys Ile Gln Lys Leu Ala Leu Lys Pro 65 70 75 80 Arg Ser Tyr Trp Ile Lys Gln Ala Gln Gln Ala Val His Ala Phe Ile 85 90 95 Arg Glu Arg Asp Arg Asp Leu Pro Cys Ile Ser Cys Gly Thr Leu Thr 100 105 110 Ser Ala Gln Trp Asp Ala Gly His Tyr Arg Thr Thr Ala Ala Ala Pro 115 120 125 Gln Leu Arg Phe Asp Glu Arg Asn Ile His Lys Gln Cys Val Val Cys 130 135 140 Asn Gln His Lys Ser Gly Asn Leu Val Pro Tyr Arg Val Glu Leu Ile 145 150 155 160 Ser Arg Ile Gly Gln Glu Ala Val Glu Glu Ile Glu Ser Asn His Asn 165 170 175 Arg Tyr Arg Trp Thr Val Glu Glu Cys Arg Ala Ile Lys Ala Glu Tyr 180 185 190 Gln Gln Lys Leu Lys Lys Leu Arg Asn Ser Arg Ser Glu Val Ala * 195 200 205 <210> 940 <211> 222 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5891..6556) <400> 940 Met Asn Ile Tyr Glu Arg Ile Asp Gly Ser Lys Tyr Arg Asn Ile Trp 1 5 10 15 Val Val Gly Asp Leu His Gly Cys Tyr Thr Asn Leu Met Lys Lys Leu 20 25 30 Glu Thr Ile Gly Phe Asp Thr Lys Lys Asp Leu Leu Ile Ser Val Gly 35 40 45 Asp Leu Val Asp Arg Gly Thr Glu Asn Val Glu Cys Leu Glu Leu Ile 50 55 60 Thr Phe Pro Trp Phe Arg Ala Val Arg Gly Asn His Glu Gln Met Met 65 70 75 80 Ile Asp Gly Leu Ser Glu Arg Gly Asn Val Asn His Trp Leu Leu Asn 85 90 95 Gly Gly Gly Trp Phe Phe Asn Leu Asp Tyr Asp Lys Glu Ile Leu Ala 100 105 110 Lys Ala Leu Ala His Lys Ala Asp Glu Leu Pro Leu Ile Ile Glu Leu 115 120 125 Val Ser Lys Gly Lys Lys Tyr Val Ile Cys His Ala Asp Tyr Pro Cys 130 135 140 Asp Lys Tyr Glu Phe Gly Lys Pro Val Asp His Gln Gln Val Ile Trp 145 150 155 160 Asn Arg Glu Arg Ile Ser Asn Ser Gln Asp Gly Ile Val Lys Glu Ile 165 170 175 Lys Gly Ala Asp Thr Phe Ile Phe Gly His Thr Pro Ala Val Lys Pro 180 185 190 Leu Lys Phe Ala Asn Gln Met Tyr Ile Asp Thr Gly Ala Val Phe Cys 195 200 205 Gly Asn Leu Thr Leu Ile Gln Val Gln Gly Glu Gly Ala * 210 215 220 <210> 941 <211> 320 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6768..7727) <400> 941 Met Lys Lys Ser Val Ile Ala Gly Val Phe Ile Ala Leu Ser Phe Thr 1 5 10 15 Thr Cys Ser Ala Ile Ala Asn Ser Leu Ala Leu Ser Leu Ala Asn Asp 20 25 30 Asp Ala Gly Lys Phe Gln Pro Ile Leu Asn Asp Ile Tyr Gly Asn Lys 35 40 45 His Glu Asn Arg Asp Asp Tyr Ser Gln Gly Leu Phe Leu Gly Tyr Ser 50 55 60 His Asp Ile Ser Asp Ser Ser Gln Leu Ser Leu His Ile Ala Gln Asp 65 70 75 80 Ile Tyr Ser Pro Ser Gly Ser Asn Lys Arg His Asn Thr Ala Val Thr 85 90 95 Gly Asp Arg Ala Phe Ser Ala Tyr Thr His Thr Gly Ile Glu Trp Asn 100 105 110 Ser Leu Ala Asn Asp Trp Ile Arg Tyr Arg Leu Gly Thr Asp Ile Gly 115 120 125 Val Val Gly Pro Asp Ala Gly Gly Gln Lys Val Gln Asn Lys Ala His 130 135 140 Glu Ile Ile Gly Ala Glu Lys Tyr His Ala Trp Asp Asp Gln Ile Glu 145 150 155 160 Asn Arg Tyr Gly Tyr Thr Val Lys Gly Met Leu Ser Met Thr Pro Ser 165 170 175 Met Asp Ile Leu Gly Ala Asn Val Gly Leu Tyr Pro Glu Val Ser Ala 180 185 190 Val Thr Gly Asn Leu Phe Gln Tyr Val Ala Tyr Gly Ala Thr Ile Ala 195 200 205 Ile Gly Asn Asp Lys Thr Phe Asn Ser Asp Asn Gly Phe Gly Leu Leu 210 215 220 Ala Pro Arg Gly Leu Met His Met Ser Asp Thr Ser Gly Phe Lys Tyr 225 230 235 240 Lys Ile Phe Ala Gly Met Glu Arg Arg Asp Val Asn Arg Asn Tyr Thr 245 250 255 Leu Glu Gly Lys Thr Ile Gln Thr Lys Gln Thr Thr Val Ser Leu Asn 260 265 270 Lys Thr Val Asp Glu Tyr Gln Val Gly Ala Thr Ile Gly Tyr Ala Pro 275 280 285 Val Ala Phe Thr Leu Ala Phe Asn Lys Val Thr Ser Glu Phe Lys Thr 290 295 300 Gly Asp Asp Tyr Ser Phe Ile Asn Gly Ala Ile Thr Phe Phe Phe * 305 310 315 <210> 942 <211> 230 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8202..8891) <400> 942 Met Asn Thr Gln Tyr Leu Gln Tyr Val Arg Glu Gln Leu Met Ala Ala 1 5 10 15 Thr Ala Asp Leu Asn Gly Ala Thr Lys Gly Gln Leu Glu Ala Trp Gln 20 25 30 Glu His Ala Gln Phe Asp Thr Gly Thr Tyr Lys Arg Lys Lys Pro Arg 35 40 45 Ile Leu Asp Val Val Thr Gly Lys Met Ile Thr Leu Asp Asn Thr Pro 50 55 60 Thr Ser Gly Lys Gln Ser Tyr Ala Lys Gly Ser Ser Ile Ala Leu Val 65 70 75 80 Ser Pro Val Glu Phe Ser Thr Ser Ser Trp Arg Arg Ala Val Leu Ser 85 90 95 Leu Asp Glu His Gln Lys Ala Trp Leu Leu Trp Cys Tyr Ser Glu Ser 100 105 110 Val Arg Trp Gly His Gln Val Thr Ile Thr Gln Trp Ala Trp Ser Glu 115 120 125 Phe Lys Asp Leu Leu Ser Asn Arg Lys Ile Ala Gly Lys Thr Leu Asp 130 135 140 Arg Leu Lys Thr Leu Ile Trp Leu Ala Ala Gln Asp Val Lys Ser Glu 145 150 155 160 Leu Ala Gly Arg Glu Ala Tyr Glu Tyr Gln Thr Leu Ala Ser Leu Val 165 170 175 Gly Val Thr Thr Lys Asn Trp Ser Glu Thr Phe Thr Glu Arg Trp Val 180 185 190 Ala Met Lys His Ile Phe Leu Gln Leu Asp Ser Asp Ala Leu Leu Leu 195 200 205 Val Thr Arg Thr Arg Ser Lys Gln Lys Ala Ala Phe Leu Gln Gln Asn 210 215 220 Ile Ala Lys Leu Asp * 225 <210> 943 <211> 223 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9150..9818) <400> 943 Met Gly Cys Leu Gly Trp Gly Ser Ala Tyr Phe Tyr Gly Trp Gly Thr 1 5 10 15 Ser Phe Tyr Tyr Gly Phe Pro Trp Trp Ile Val Gly Ala Gly Val Asp 20 25 30 Asp Val Ala Arg Ser Leu Phe Phe Ala Val Ile Val Ile Ala Ile Phe 35 40 45 Leu Ile Gly Trp Gly Ile Gly Val Val Phe Phe Phe Ala Val Lys Arg 50 55 60 Lys His Ser Met Gln Glu Leu Asn Val Phe Arg Leu Tyr Phe Ala Val 65 70 75 80 Glu Leu Leu Phe Val Pro Ala Ile Ile Glu Phe Ser Ile Leu Arg Gln 85 90 95 Lys Ile Gln Val Pro Leu Leu Leu Leu Ser Ala Ala Ile Ala Leu Ala 100 105 110 Val Thr Ile Ser Ile Arg Ser Tyr Gly Arg Phe Leu Ser Val Ser Cys 115 120 125 Phe Tyr Asp Lys Pro Phe Ile Lys Lys His Phe Phe Glu Ile Val Met 130 135 140 Ile Ala Phe Val Ala Tyr Phe Trp Leu Phe Ser Phe Leu Thr Gly Tyr 145 150 155 160 Tyr Lys Pro Gln Phe Lys Lys Glu Tyr Glu Met Ile Asn Tyr Asn Asp 165 170 175 Gly Trp Tyr Tyr Val Leu Ala Arg Tyr Asp Asn Cys Leu Val Leu Ser 180 185 190 Thr Ser Phe Asn Ala Gly Ser Lys Arg Phe Val Ile Tyr Gln Ser Ala 195 200 205 Gln Asp Lys Asn Leu Gln Val Asp Ile Val Arg Thr Arg Ile * 210 215 220 <210> 944 <211> 133 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10143..10541) <400> 944 Val Leu His Ile Ile Ser Pro Arg Gly Ile Ser Pro Arg Gln Arg Arg 1 5 10 15 Leu Phe Tyr Pro Phe Ser Ser Ala Leu Ala Leu Phe Tyr Tyr Ala Ala 20 25 30 Ala Phe Thr Ser Gly Thr Met Leu Ser Ile Ser Thr Gln Tyr Val Val 35 40 45 Leu Leu Val Thr Asn Ile Ile Thr Ile Asn Arg His Arg Ile Ser Pro 50 55 60 Val Tyr Arg Asn Arg Val Lys Lys Pro Glu Pro Glu Ser Asn His Arg 65 70 75 80 Met Thr Ile Cys Gln Trp Gln Val Ile Lys Lys Arg Pro Arg His Ala 85 90 95 Gln Pro Glu Leu Thr Arg Lys Met Ile Glu Gly Asn Asn Ile Ser Asp 100 105 110 Val Arg Met Ala Pro Pro Ala Lys Phe Cys Asn Asp Gln Thr Glu Leu 115 120 125 Ala Thr Cys Pro * 130 <210> 945 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10684..10899) <400> 945 Met Tyr Gln Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser 1 5 10 15 Ala Val Gly Thr Gly Tyr Trp Leu Leu Gln Leu Leu Asp Lys Val Ser 20 25 30 Pro Ser Gln Trp Val Ala Ile Gly Val Leu Gly Ser Leu Val Phe Gly 35 40 45 Leu Leu Thr Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Lys Glu Asp Lys 50 55 60 Arg Lys Ala Ala Arg Gly Glu * 65 70 <210> 946 <211> 166 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10899..11396) <400> 946 Met Ser Pro Ser Leu Arg Lys Ala Val Ala Ala Ala Ile Gly Gly Gly 1 5 10 15 Ala Ala Ala Ile Ala Ser Val Leu Ile Thr Gly Pro Ser Gly Asp Asp 20 25 30 Gly Leu Glu Gly Val Ser Tyr Ile Pro Tyr Glu Asp Ile Val Gly Val 35 40 45 Trp Thr Val Cys His Gly His Thr Gly Lys Asp Ile Ile Pro Gly Lys 50 55 60 Thr Tyr Thr Glu Ala Glu Cys Lys Ala Leu Leu Asn Lys Asp Leu Ala 65 70 75 80 Thr Val Ala Arg Gln Ile Asn Pro Tyr Ile Lys Val Asp Ile Pro Glu 85 90 95 Thr Thr Arg Gly Ala Leu Tyr Ser Phe Val Tyr Asn Val Gly Ala Gly 100 105 110 Asn Phe Arg Thr Ser Thr Leu Leu Arg Lys Ile Asn Gln Gly Asp Ile 115 120 125 Lys Gly Ala Cys Asp Gln Leu Arg Arg Trp Thr Tyr Ala Gly Gly Lys 130 135 140 Gln Trp Lys Gly Leu Met Thr Arg Arg Glu Ile Glu Arg Glu Val Cys 145 150 155 160 Leu Trp Gly Gln Gln * 165 <210> 947 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11393..11860) <400> 947 Met Ser Arg Val Thr Ala Ile Ile Ser Ala Leu Val Ile Cys Ile Ile 1 5 10 15 Val Cys Gln Ser Trp Ala Val Asn His Tyr Arg Asp Asn Ala Ile Ala 20 25 30 Tyr Lys Glu Gln Arg Asp Lys Lys Val Ser Glu Leu Lys Gln Ala Thr 35 40 45 Ala Thr Ile Thr Asp Met Gln Gln Arg Gln Arg Ala Ala Asp Ala Leu 50 55 60 Asp Ala Lys Tyr Thr Lys Glu Leu Ala Asp Ala Lys Ala Lys Asn Asp 65 70 75 80 Ala Leu Arg Arg Lys Leu Asp Asn Gly Gly Arg Val Phe Val Lys Gly 85 90 95 Lys Cys Pro Val Pro Ser Ser Asp Glu Thr Ser Ser Ala Ser Gly Met 100 105 110 Gly Asn Asp Ala Thr Val Glu Leu Ser Pro Val Ala Gly Arg Asn Val 115 120 125 Leu Gly Ile Arg Asp Gly Ile Ile Arg Asp Gln Thr Ala Leu Arg Thr 130 135 140 Leu Gln Glu Tyr Ile Arg Thr Gln Cys Leu Arg * 145 150 155 <210> 948 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11613..11819) <400> 948 Met Arg Lys Leu Lys Met Met Leu Phe Gly Ala Ser Leu Ile Met Val 1 5 10 15 Val Gly Cys Ser Ser Lys Glu Asn Ala Leu Cys His Pro Gln Thr Lys 20 25 30 Pro Pro Ala Pro Pro Ala Trp Ala Met Met Pro Pro Ser Asn Ser Leu 35 40 45 Gln Leu Leu Asp Glu Thr Phe Ser Val Ser Gly Thr Glu Leu Ser Ala 50 55 60 Thr Lys Gln His * 65 <210> 949 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11848..12000) <400> 949 Met Pro Ser Met Ile Ala Ile Ile Leu Leu Ile Ile Leu His Ile Trp 1 5 10 15 Leu Cys Arg Gln Gly Gly Ala His Phe Trp Ser Glu Ser Trp Leu Asn 20 25 30 Ile Ser Leu Leu Met Leu Asp Ile Glu His Leu Ala Arg Gly Lys Gly 35 40 45 Leu Arg * 50 <210> 950 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12407..12685) <400> 950 Met Pro Phe Met Gln Gly Leu Tyr Gln Thr Phe Val Met Ala Phe Arg 1 5 10 15 Leu Thr Ala Pro Pro Gly Gly Val Ala Cys His Gly Ala Gly Ala Ser 20 25 30 Arg Lys Lys Ala Ser Phe Cys Ile Phe Ile Gly His His His Leu Cys 35 40 45 Ile Leu Leu Ile Ile Asn Gly Tyr Leu Phe Phe Val Cys Arg Ile Glu 50 55 60 Cys Phe Leu Phe Asp Ile Glu Arg Val Phe Leu Lys Leu Phe Ala Arg 65 70 75 80 Cys Met Phe Lys Ala Leu Arg Arg Lys Tyr Gly Ser * 85 90 <210> 951 <211> 164 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12675..13166) <400> 951 Met Asp His Glu Leu Lys Asn Leu Val Leu Asn Ile Asn Gln Leu Ala 1 5 10 15 Ala Leu Ser Gly Leu His Arg Gln Thr Val Val Ala Arg Leu Lys Asn 20 25 30 Ile Arg Pro Ala Gly Gly His Asp Lys Leu Lys Leu Tyr Arg Leu Thr 35 40 45 Asp Ile Leu Thr Glu Phe Met Gly Leu Pro Pro Pro Val Ala Glu Gly 50 55 60 Glu Met Asp Pro His Glu Arg Lys Ala Trp Tyr Gln Ser Glu Arg Glu 65 70 75 80 Arg Leu Lys Phe Glu Gln Glu Thr Ala Gln Leu Ile Pro Ala Ser Asp 85 90 95 Val Arg Arg Glu Phe Ala Ile Trp Ala Lys Ala Val Val Gln Val Leu 100 105 110 Glu Thr Leu Pro Asp Ile Leu Glu Arg Asp Cys Gly Leu Gln Pro Ala 115 120 125 Ala Val Ser Arg Val Gln Ser Ile Ile Asp Asp Leu Arg Asp Gln Ile 130 135 140 Ala Leu Arg Val Thr Glu Ala Gly Ala Asp Asp Glu Glu Glu Leu Gln 145 150 155 160 Gln Glu Glu * <210> 952 <211> 701 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13166..15268) <400> 952 Met Leu Asn Gln Glu Thr Ala Lys Ala Ala Arg Thr Asp Ser Gly Tyr 1 5 10 15 Ile Leu Arg Ala Pro Arg Arg Met Arg Val Ala Asp Ala Val Ala Gln 20 25 30 Tyr Met Arg Val Pro Met Gly Ala Gly Asn Ser Val Pro Trp Asp Pro 35 40 45 Leu Val Ala Pro Tyr Val Ile Glu Pro Met Asn Cys Leu Ala Ser Arg 50 55 60 Glu Tyr Asp Ala Val Ile Phe Val Gly Pro Ala Arg Thr Gly Lys Thr 65 70 75 80 Ile Gly Leu Ile Asp Gly Trp Val Ile Tyr Asn Val Ile Cys Asp Pro 85 90 95 Ala Asp Met Leu Ile Ile Gln Met Thr Glu Glu Lys Ala Arg Glu His 100 105 110 Ser Lys Lys Arg Leu Ala Arg Thr Phe Arg Val Ser Pro Glu Val Val 115 120 125 Ser Arg Leu Ser Pro Asn Lys Asn Asp Asn Asn Val Tyr Asp Arg Thr 130 135 140 Phe Leu Ala Gly Asn Tyr Leu Lys Ile Gly Trp Pro Ser Val Asn Ile 145 150 155 160 Met Ser Ser Ser Asp Tyr Lys Cys Val Ala Leu Thr Asp Tyr Asp Arg 165 170 175 Phe Pro Glu Asp Ile Asp Gly Glu Gly Asp Ala Phe Ser Leu Ala Ser 180 185 190 Lys Arg Thr Thr Thr Phe Met Ser Ser Gly Met Thr Leu Val Glu Ser 195 200 205 Ser Pro Gly Arg Asp Val Lys Asp Val Lys Trp Arg Arg Thr Ser Pro 210 215 220 His Glu Ala Pro Pro Thr Thr Gly Ile Leu Ser Leu Tyr Asn Arg Gly 225 230 235 240 Asp Arg Arg Arg Trp Tyr Trp Pro Cys Pro His Cys Gly Glu Tyr Phe 245 250 255 Gln Pro Cys Gly Asp Val Val Ala Gly Phe Arg Asp Ile Ala Asp Pro 260 265 270 Val Leu Ala Ser Glu Ala Ala Tyr Ile Gln Cys Pro Ser Cys Ser Gly 275 280 285 Arg Ile Met Pro Glu Gln Lys Arg Glu Leu Asn Gly Arg Gly Val Trp 290 295 300 Leu Arg Asp Gly Glu Ser Ile Asn Ala Asp Gly Ser Arg Tyr Gly Asp 305 310 315 320 Pro Arg Arg Ser Arg Ile Ala Ser Phe Trp Met Glu Gly Pro Ala Ala 325 330 335 Ala Tyr Gln Thr Leu Ser Gln Leu Val Tyr Lys Leu Leu Thr Ala Glu 340 345 350 Gln Glu Tyr Glu Thr Thr Gly Ser Glu Glu Thr Leu Lys Thr Val Ile 355 360 365 Asn Thr Asp Trp Gly Leu Pro Tyr Leu Pro Arg Ala Ser Met Glu Gln 370 375 380 Arg Lys Ser Glu Leu Leu Glu Gln Arg Ala Glu Pro Val Pro Ser Ser 385 390 395 400 Ser Val Pro Asp Gly Val Asn Phe Leu Val Ala Thr Val Asp Val Gln 405 410 415 Ala Gly Arg His Arg Arg Phe Val Val Gln Val Thr Gly Tyr Gly Ser 420 425 430 Arg Gly Glu Arg Trp Ile Ile Asp Arg Tyr Asn Ile Thr Gln Ser Leu 435 440 445 Arg Gly Asp Ser Asp Gly Glu Ser Gln Arg Ile Asp Pro Ala Ser Tyr 450 455 460 Pro Glu Asp Trp Asp Val Leu Leu Thr Asp Val Phe His Lys Ser Trp 465 470 475 480 Pro Leu Ala Ser Asp Pro Ser Gln Gln Met Arg Leu Met Ala Met Ala 485 490 495 Val Asp Ser Gly Gly Glu Asp Gly Val Thr Asp Asn Ala Tyr Lys Phe 500 505 510 Trp Arg Arg Cys Arg Arg Asp Gly Leu Gly Lys Arg Ile Tyr Leu Phe 515 520 525 Lys Gly Asp Ser Ile Arg Arg Ala Lys Leu Ile Thr Arg Thr Phe Pro 530 535 540 Asp Asn Thr Gly Arg Thr Gly Arg Arg Ala Gln Ala Ala Gly Asp Val 545 550 555 560 Pro Leu Trp Leu Leu Gln Thr Asp Ala Leu Lys Asp Arg Val Asn Asn 565 570 575 Ala Leu Trp Arg Asp Ser Pro Gly Pro Gly Tyr Val His Phe Pro Asp 580 585 590 Trp Leu Gly Ser Trp Phe Tyr Asp Glu Leu Thr Tyr Glu Glu Arg Ser 595 600 605 Ser Asp Gly Lys Trp Ser Lys Pro Gly Arg Gly Ala Asn Glu Ala Phe 610 615 620 Asp Leu Met Val Tyr Ala Glu Ala Leu Val Ile Leu His Gly Tyr Glu 625 630 635 640 Lys Ile Arg Trp Pro Asp Ala Pro Gly Trp Ala Ser Arg Glu Thr Trp 645 650 655 Leu Glu Ser Val Pro Asp Ser Thr Glu Pro Ser Pro Ser Pro Glu Pro 660 665 670 Val Ser Thr Pro Val Lys Lys Gln Lys Arg Lys Lys Thr Val Thr Asp 675 680 685 Asp Val Asn Pro Trp Leu Thr Ser Gly Gly Trp Leu * 690 695 700 <210> 953 <211> 71 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15265..15477) <400> 953 Met Asn Gln Asn Asp Ile Glu Ala Met Ile Gln Arg Tyr Thr Glu Ala 1 5 10 15 Glu Met Ala Val Leu Asp Gly Lys Ser Val Thr Phe Asn Gly Gln Gln 20 25 30 Met Thr Met Glu Asn Leu Ser Glu Ile Arg Gln Gly Arg Gln Glu Trp 35 40 45 Glu Arg Arg Leu Ala Ala Leu Ile Thr Arg Arg Arg Gly His Pro Gly 50 55 60 Tyr Arg Leu Ala Arg Phe * 65 70 <210> 954 <211> 375 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15405..16529) <400> 954 Val Gly Ala Pro Pro Cys Gly Ser Asp Tyr Thr Thr Thr Gly Ala Ser 1 5 10 15 Arg Val Pro Ala Gly Glu Val Leu Met Ala Ile Leu Asp Asp Val Ile 20 25 30 Gly Val Phe Ser Pro Gly Trp Lys Ala Ala Arg Leu Arg Ser Arg Ala 35 40 45 Val Ile Gln Ala Tyr Glu Ala Val Lys Thr Thr Arg Thr His Lys Ala 50 55 60 Arg Arg Glu Asn Arg Thr Ala Asp Gln Leu Ser Gln Tyr Gly Ala Val 65 70 75 80 Ser Leu Arg Glu Gln Ala Arg Tyr Leu Asp Asn Asn His Asp Leu Val 85 90 95 Ile Gly Val Phe Asp Lys Leu Glu Glu Arg Val Val Gly Lys Asn Gly 100 105 110 Ile Ile Val Glu Pro His Pro Val Leu Arg Asn Gly Ala Ile Ala Arg 115 120 125 Asp Leu Ala Ala Glu Ile Arg Thr Arg Trp Ser Glu Trp Ser Val Ser 130 135 140 Pro Glu Val Thr Gly Gln Phe Thr Arg Pro Met Leu Glu Arg Leu Met 145 150 155 160 Leu Arg Thr Trp Leu Arg Asp Gly Glu Val Phe Ala Gln Met Val Ser 165 170 175 Gly Arg Ile Asn Ser Leu Thr Pro Ser Ala Gly Val His Phe Trp Leu 180 185 190 Glu Ala Leu Glu Pro Asp Phe Ile Pro Met Thr Ser Asp Glu Ser Asn 195 200 205 Arg Leu Asn Gln Gly Val Phe Val Asp Asp Trp Gly Arg Pro Glu Lys 210 215 220 Tyr Leu Val Tyr Lys Ser Arg Pro Val Ser Gly Arg Gln Met Glu Thr 225 230 235 240 Lys Glu Val Asp Ala Glu Arg Met Leu His Leu Lys Phe Val Arg Arg 245 250 255 Leu His Gln Met Arg Gly Thr Ser Leu Leu Ser Gly Val Leu Ile Arg 260 265 270 Leu Ser Ala Leu Lys Glu Tyr Glu Asp Ser Glu Leu Thr Ala Ala Arg 275 280 285 Ile Ala Ala Ala Leu Gly Met Tyr Ile Arg Lys Gly Asp Gly Gln Ser 290 295 300 Tyr Glu Pro Asp Gly Asn Gly Ser Lys Asp Lys Glu Arg Glu Leu Thr 305 310 315 320 Ile Gln Pro Gly Ile Ile Tyr Asp Asp Leu Lys Pro Gly Glu Glu Ile 325 330 335 Gly Met Val Lys Ser Asp Arg Pro Asn Pro Asn Leu Glu Thr Phe Arg 340 345 350 Asn Gly Gln Leu Arg Ala Val Ala Ala Gly Ser Arg Leu Asn Phe Phe 355 360 365 Gln Tyr Ser Ala Gln Leu * 370 <210> 955 <211> 86 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16729..16986) <400> 955 Met Pro Trp Ile Asp Pro Val Lys Glu Ala Glu Ala Trp Lys Ile Gln 1 5 10 15 Ile Arg Gly Gly Ala Ala Thr Glu Ser Asp Trp Val Arg Ala Gly Gly 20 25 30 Arg Asn Pro Asp Asp Val Lys Arg Arg Arg Lys Ala Glu Ile Asp Glu 35 40 45 Asn Arg Lys Leu Asp Leu Val Phe Asp Thr Asp Pro Ala Ser Asp Lys 50 55 60 Gly Gly Ser Ser Ala Ala Thr Lys Arg Gln Glu Pro Gln His Thr Asp 65 70 75 80 Asp Gln Ser Glu Glu * 85 <210> 956 <211> 708 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16835..18958) <400> 956 Met Met Ser Asn Val Gly Ala Arg Pro Lys Leu Met Lys Thr Ala Ser 1 5 10 15 Trp Ile Trp Tyr Leu Ile Pro Ile Arg Pro Val Ile Lys Glu Ala Ala 20 25 30 Val Pro Gln Arg Asn Asp Arg Ser Arg Ser Thr Pro Thr Thr Ser Pro 35 40 45 Lys Asn Asn Ser Trp Phe Arg Met Gln Ala Gly His Gln Ser Asp Ala 50 55 60 Asp Ile Tyr Ile Tyr Asp Glu Ile Gly Phe Trp Gly Val Thr Ala Lys 65 70 75 80 Gln Phe Ile Ser Asp Leu Asn Ala Leu Gly Asp Ile Thr His Ile Asn 85 90 95 Leu Asn Ile Asn Ser Pro Gly Gly Asp Val Phe Glu Gly Ile Ala Ile 100 105 110 Phe Asn Ala Leu Lys Thr His Gly Ala Ser Ile Thr Val Tyr Val Asp 115 120 125 Gly Val Ala Ala Ser Met Ala Ser Val Ile Ala Met Val Gly Lys Pro 130 135 140 Val Ile Met Pro Glu Asn Ser Phe Met Met Ile His Lys Pro Phe Gly 145 150 155 160 Phe Thr Gly Gly Asp Ala Glu Asp Met Arg Thr Tyr Ala Asp Leu Leu 165 170 175 Asp Lys Val Glu Ala Val Leu Leu Pro Ala Tyr Ala Gln Lys Thr Gly 180 185 190 Lys Thr Thr Asp Glu Ile Ala Ala Met Leu Ala Asp Glu Thr Trp Met 195 200 205 Ser Gly Ala Glu Cys Leu Ala His Gly Phe Ala Asp Gln Val Thr Pro 210 215 220 Ala Val Lys Ala Met Ala Cys Ile Gln Ser Lys Arg Thr Glu Glu Phe 225 230 235 240 Lys Lys Met Pro Glu Ser Ile Arg Asn Met Ile Thr Pro Pro Arg Asn 245 250 255 Ser Ala Pro Arg Val Gln Asp Asp Gly Pro Ala Ala Ser Arg Thr Pro 260 265 270 Val Gln Ala Ala Ala Pro Val Val Asp Glu Asn Ser Ile Arg Ala Gln 275 280 285 Val Leu Ala Glu Gln Lys Ala Arg Val Asn Gly Ile Asn Asp Leu Phe 290 295 300 Ala Met Phe Gly Gly Arg Tyr Gln Thr Leu Gln Ala Gln Cys Leu Ala 305 310 315 320 Asp Pro Glu Cys Ser Leu Glu Gln Ala Arg Glu Lys Leu Leu Asn Glu 325 330 335 Met Gly Arg Glu Ser Thr Pro Ser Asn Lys Asn Thr Pro Ala His Ile 340 345 350 Tyr Ala Gly Asn Gly Asn Phe Val Gly Asp Gly Ile Arg Gln Ala Leu 355 360 365 Met Ala Arg Ala Gly Phe Glu Lys Thr Glu Arg Asp Asn Val Tyr Asn 370 375 380 Gly Met Thr Leu Arg Glu Tyr Ala Arg Met Ser Leu Thr Glu Arg Gly 385 390 395 400 Ile Gly Val Ser Ser Tyr Asn Pro Met Gln Met Val Gly Ala Ala Phe 405 410 415 Thr His Ser Thr Ser Asp Phe Gly Asn Ile Leu Leu Asp Val Ala Asn 420 425 430 Lys Ala Ile Leu Gln Gly Trp Glu Asp Ala Pro Glu Thr Tyr Glu Gln 435 440 445 Trp Thr Arg Lys Gly Gln Leu Ser Asp Phe Lys Ile Ala His Arg Val 450 455 460 Gly Met Gly Gly Phe Ser Ala Leu Arg Gln Val Arg Glu Gly Ala Glu 465 470 475 480 Tyr Lys Tyr Val Thr Thr Gly Asp Lys Gln Ala Thr Ile Ala Leu Ala 485 490 495 Thr Tyr Gly Glu Leu Phe Ser Ile Thr Arg Gln Ala Ile Ile Asn Asp 500 505 510 Asp Leu Asn Met Leu Thr Asp Val Pro Met Lys Leu Gly Arg Ala Ala 515 520 525 Lys Ser Thr Ile Ala Asp Leu Val Tyr Ala Ile Leu Thr Ser Asn Pro 530 535 540 Lys Ile Ser Thr Asp Asn Val Ser Leu Phe Asp Lys Ala Lys His Ala 545 550 555 560 Asn Val Leu Glu Ser Ala Ala Met Asp Val Ala Ser Leu Asp Lys Ala 565 570 575 Arg Gln Leu Met Arg Val Gln Lys Glu Gly Glu Arg His Leu Asn Ile 580 585 590 Arg Pro Ala Phe Val Leu Val Pro Thr Ala Met Glu Ser Val Ala Asn 595 600 605 Gln Val Ile Arg Ser Ser Ser Val Lys Gly Ala Asp Ile Asn Ala Gly 610 615 620 Ile Ile Asn Pro Val Lys Asp Phe Ala Thr Val Ile Ala Glu Pro Arg 625 630 635 640 Leu Asp Asp Asn Ser Gln Thr Thr Phe Tyr Leu Ala Ala Ser Lys Gly 645 650 655 Ser Asp Thr Ile Glu Val Ala Tyr Leu Asn Gly Val Asp Thr Pro Tyr 660 665 670 Ile Asp Gln Met Glu Gly Phe Ser Val Asp Gly Val Thr Thr Lys Val 675 680 685 Arg Ile Asp Ala Gly Val Ala Pro Val Asp His Arg Gly Leu Val Lys 690 695 700 Cys Thr Ala * 705 <210> 957 <211> 123 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19000..19368) <400> 957 Leu Tyr Leu Lys Ser Ala Pro Glu Arg Gly Cys Ala Glu Thr Val Met 1 5 10 15 Ala Lys Asn Phe Val Glu Glu Gly Lys Thr Val Ala Ile Val Ala Ser 20 25 30 Ala Ala Ile Ser Ser Gly Asp Leu Val Gln Val Gly Asp Val Phe Ala 35 40 45 Val Ala Leu Thr Asp Ile Pro Gln Gly Glu Thr Gly Asp Gly Met Thr 50 55 60 Glu Gly Val Phe Met Leu Pro Lys Leu Lys Thr Asp Asp Met Lys Thr 65 70 75 80 Gly Lys Lys Val Tyr Leu Lys Ser Gly Lys Val Gln Leu Thr Asn Ser 85 90 95 Gly Ser Asp Pro Leu Val Gly Val Val Trp Ala Asp Ala Gly Thr Ser 100 105 110 Ala Glu Glu Val Pro Val Lys Leu Asn Val * 115 120 <210> 958 <211> 92 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19361..19636) <400> 958 Met Ser Asp Pro Phe Ser Arg Leu Ala Ala Arg Met Asp Ala Ile Thr 1 5 10 15 Val Arg Lys Met Gly Lys Thr Ala Ser Ile Asn Asp Val Asp Met Thr 20 25 30 Val Ile Pro Gly Glu Thr Leu Ala Glu Leu Asn Ala Leu Ser Gly Pro 35 40 45 Ala Val Ser Leu Val Val Phe Ser Ser Gly Tyr Arg Pro Arg Arg Gly 50 55 60 Asp Arg Val Val Tyr Asp Gly Gln Gln Trp Thr Val Thr Arg His Glu 65 70 75 80 Arg Phe Asn Gly Lys Pro Met Ile Phe Ile Glu * 85 90 <210> 959 <211> 193 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19648..20226) <400> 959 Met Lys Gly Leu Glu Asn Ala Ile Arg Asn Leu Asn Ser Leu Asp Thr 1 5 10 15 Arg Met Val Pro Gln Ala Ser Ala Trp Ala Ile Asn Arg Val Ala Gln 20 25 30 Lys Ala Gly Ser Val Ala Thr Arg Gln Val Ala Gly Asn Thr Val Ala 35 40 45 Gly Asp Asn Gln Val Lys Gly Ile Pro Leu Lys Leu Val Arg Gln Arg 50 55 60 Val Arg Val Phe Lys Ala Ser Pro Ser Gly Lys Met Thr Ala Arg Ile 65 70 75 80 Arg Val Asn Arg Gly Asn Leu Pro Ala Ile Lys Leu Gly Thr Ala Arg 85 90 95 Val Arg Leu Ala Gln Arg Gly Gly Lys Leu Gln Tyr Arg Gly Ser Val 100 105 110 Leu Lys Val Gly Lys Tyr Leu Phe Arg Asp Ala Phe Ile Gln Gln Leu 115 120 125 Ala Asn Gly Arg Trp His Val Met Arg Arg Ile Asp Gly Lys Asn Arg 130 135 140 Tyr Pro Ile Asp Val Val Lys Ile Pro Leu Ser Gly Pro Leu Thr Gln 145 150 155 160 Ala Phe Glu Asp Ala Arg Asp Arg Ile Ile Ala Ala Glu Met Pro Lys 165 170 175 Gln Leu Gly Tyr Ala Leu Lys Gln Gln Leu Arg Leu Trp Leu Thr Arg 180 185 190 * <210> 960 <211> 134 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20223..20624) <400> 960 Met Asn Arg His Thr Gln Ile Arg Gln Val Val Leu Ala Arg Leu Arg 1 5 10 15 Glu Gln Cys Gly Asp Ser Ala Thr Phe Phe Asp Gly Leu Pro Ala Phe 20 25 30 Val Asp Ala Gln Glu Leu Pro Ala Val Ala Val Trp Leu Ser Asp Ala 35 40 45 Gln Tyr Thr Gly Lys Met Thr Asp Glu Asp Asp Trp Gln Ala Val Leu 50 55 60 His Ile Ala Val Phe Ile Arg Ala Gln Ala Pro Asp Ser Glu Leu Asp 65 70 75 80 Met Trp Met Glu Ser Thr Ile Phe Pro Ala Leu Asn Asp Val Ser Ala 85 90 95 Leu Ser Gly Leu Ile Asp Thr Leu Ile Pro Leu Gly Phe Asn Tyr Gln 100 105 110 Arg Asp Asn Glu Met Ala Thr Trp Ala Met Ala Glu Ile Thr Tyr Gln 115 120 125 Ile Thr Tyr Thr Asn * 130 <210> 961 <211> 248 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20635..21378) <400> 961 Met Thr Thr Pro Asn Pro Leu Ala Lys Thr Lys Gly Ala Gly Thr Thr 1 5 10 15 Phe Trp Met Tyr Thr Gly Asn Gly Asp Ala Phe Ala Asn Pro Leu Ser 20 25 30 Asp Thr Asp Trp Leu Arg Leu Ala Met Val Lys Asp Leu Gln Pro Gly 35 40 45 Glu Met Thr Ala Asp Ala Glu Asp Asp Thr Tyr Leu Asp Asp Glu Asp 50 55 60 Ala Asp Trp Lys Thr Thr Thr Gln Gly Gln Lys Ser Val Gly Asp Thr 65 70 75 80 Ser Ala Thr Leu Ala Trp Arg Pro Gly Asp Ser Gly Gln Lys Lys Leu 85 90 95 Val Gln Leu Phe Asp Ser Gly Glu Val Cys Ala Phe Arg Ile Lys Tyr 100 105 110 Pro Asn Gly Thr Val Asp Val Phe Arg Gly Trp Leu Ser Ser Leu Gly 115 120 125 Lys Thr Ile Ala Ser Lys Asp Val Met Thr Arg Thr Val Lys Ile Ser 130 135 140 Gly Val Gly Arg Pro Tyr Leu Ala Glu Glu Gly Thr Glu Thr Val Gly 145 150 155 160 Val Thr Gly Leu Thr Val Ala Pro Ala Ser Ala Ser Val Asn Val Gly 165 170 175 Ala Thr Thr Thr Leu Thr Phe Thr Val Lys Pro Asp Gly Ala Ser Asp 180 185 190 Lys Ala Ile Ser Val His Ser Thr Asp Pro Gln Thr Ala Thr Val Thr 195 200 205 Leu Asn Gly Leu Val Ala Thr Val Lys Gly Val Lys Gln Gly Ser Val 210 215 220 Ser Ile Val Gly Met Thr Ala Asp Gly Asn Phe Val Ala Val Ala Ala 225 230 235 240 Val Thr Val Ser Ala Ala Gly * 245 <210> 962 <211> 129 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21439..21825) <400> 962 Met Phe Leu Lys Gln Gly Thr Phe Asn Tyr Glu Lys Gln Ser Val Val 1 5 10 15 Leu Ser Glu Leu Ser Gly Leu Gln Arg Ile Glu Tyr Leu Ala Phe Val 20 25 30 Gln Gln Arg Thr Ala Lys Phe Asp Ala Glu Glu Gly Glu Leu Pro Glu 35 40 45 Ala Glu Arg Gln Ile Ala Phe Leu Arg Met Gly Met Asp Ile Asn Ala 50 55 60 Trp Leu Val Ser Arg Ser Leu Trp Asn Ala Glu Gln Ser Gln Asp Val 65 70 75 80 Glu Thr Leu Cys Ala Ser Val Ile Thr Thr Trp Ser Tyr Asp Ala Leu 85 90 95 Gly Ala Gly Ala Glu Met Val Leu Ser Leu Ser Gly Met Gly Ala Ile 100 105 110 Glu Asn Ala Gly Asp Leu Glu His Glu Val Leu Thr Pro Glu Lys Ser 115 120 125 * <210> 963 <211> 110 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21834..22163) <400> 963 Met Gln Phe Val Met Arg Leu Ala Arg Glu Phe Arg Arg Ala Asp Trp 1 5 10 15 Arg Arg Met Leu Ser Glu Met Ser Ala Thr Glu Leu Gly Glu Trp Gly 20 25 30 Asp Tyr Phe Arg Met Gln Ser Phe Ser Asp Val Trp Met Asp Ala Gln 35 40 45 Phe Ala Ser Leu Lys Ala Leu Ile Val Arg Met Val Ser Gly Ser Ser 50 55 60 Asp Ala Ala Val Ala Asp Phe Ser Leu Leu Pro Glu Glu Asn Gly Ile 65 70 75 80 Pro Glu Arg Thr Asp Glu Glu Leu Met His Leu Gly Glu Gly Ile Ser 85 90 95 Gly Gly Val Arg Tyr Gly Pro Asp Ser Gln Pro Gly His * 100 105 <210> 964 <211> 1022 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22135..25200) <400> 964 Met Asp Gln Ile Ala Asn Leu Val Ile Asp Leu Gly Ile Asp Ala Ala 1 5 10 15 Glu Phe Lys Asn Glu Ile Pro Arg Ile Lys Asn Leu Leu Asn Gly Ala 20 25 30 Ala Ser Asp Ala Glu Arg Ser Ser Ala Arg Met Gln Arg Phe Met Glu 35 40 45 Arg Gln Thr Gln Ala Ala Arg Gln Thr Met Gln Ala Ala Ser Ser Ala 50 55 60 Ala Thr Ala Ala Ser Val His Ala Gln Thr Val Glu Lys Ser Ala Gln 65 70 75 80 Ala His Glu Arg Met Ala Arg Glu Val Glu Gln Thr Arg Gln Arg Met 85 90 95 Glu Ala Leu Ser Gln Lys Met Arg Glu Glu Gln Ala Gln Ala Met Ala 100 105 110 Leu Ala Glu Ala Gln Asp Lys Ala Ala Ala Ala Phe Tyr Arg Gln Ile 115 120 125 Asp Ser Val Lys Gln Ala Gly Ala Gly Leu Gln Glu Leu Gln Arg Ile 130 135 140 Gln Gln Gln Ile Arg Gln Ala Arg Asn Ser Gly Gly Ile Gly Gln Gln 145 150 155 160 Asp Tyr Leu Ala Leu Ile Ser Glu Val Thr Ala Lys Thr Arg Val Leu 165 170 175 Thr Gln Ala Glu Glu Glu Ala Thr Arg Gln Lys Val Ala Phe Ile Arg 180 185 190 Gln Leu Lys Glu Gln Ala Thr Arg Gln Asn Leu Ser Ser Ser Glu Leu 195 200 205 Leu Arg Ala Lys Ala Ala Gln Leu Gly Val Ser Ser Ala Ala Glu Val 210 215 220 Tyr Ile Arg Lys Met Glu Gln Ala Gly Lys Ala Thr His Ser Leu Gly 225 230 235 240 Leu Lys Ser Ala Ala Ala Arg Gln Glu Ile Gly Val Leu Ile Gly Glu 245 250 255 Leu Ala Arg Gly Asn Leu Gly Ala Leu Arg Gly Ser Gly Ile Thr Leu 260 265 270 Ala Asn Arg Ala Gly Trp Ile Asp Thr Leu Met Ser Pro Lys Gly Met 275 280 285 Met Pro Gly Ala Val Ile Gly Gly Ile Ala Ala Ala Val Tyr Gly Leu 290 295 300 Gly Lys Ala Trp Tyr Asp Gly Gln Lys Glu Gly Glu Glu Phe Asn Arg 305 310 315 320 Gln Leu Ser Leu Thr Gly His Tyr Ala Gly Val Thr Ala Gly Gln Leu 325 330 335 Trp Thr Leu Ser Arg Ala Ile Ser Gly Asn Gly Ile Thr Gln His Ala 340 345 350 Ala Ala Gly Ala Leu Ala Gln Val Val Gly Ser Gly Ala Phe Arg Gly 355 360 365 Asn Asp Ile Gly Met Val Ala Arg Ala Ala Ala Gln Met Glu Arg Ser 370 375 380 Val Gly Gln Ser Val Ser Asp Thr Ile Asn Gln Phe Lys Arg Leu Lys 385 390 395 400 Asp Asp Pro Val Asn Ala Ala Lys Ala Leu Asp Asn Glu Leu His Phe 405 410 415 Leu Thr Ala Thr Gln Leu Glu Gln Ile Arg Val Leu Gly Glu Gln Gly 420 425 430 Arg Ser Ser Asp Ala Ala Arg Ile Ala Met Ser Ala Leu Ala Glu Glu 435 440 445 Thr Gly Arg Arg Thr Ala Asp Ile Asp Asn Asn Leu Asn Ala Leu Gly 450 455 460 Ser Thr Leu Lys Tyr Leu Ser Asp Leu Trp Ser Arg Phe Trp Asp Ala 465 470 475 480 Ala Met Asn Ile Gly Arg Glu Asp Ser Leu Asp Glu Gln Ile Ala Ala 485 490 495 Leu Gln Glu Lys Val Ser Arg Ala Lys Arg Leu Pro Trp Thr Ala Ser 500 505 510 Ser Ser Gln Val Glu Tyr Asp Gln Gln Arg Leu Asn Asp Leu Gln Glu 515 520 525 Lys Lys Arg Gln Lys Asp Leu Gln Asp Ala Lys Glu Gln Ala Glu Arg 530 535 540 Asn Tyr Gln Glu Gln Gln Lys Arg Arg Asn Ala Glu Asn Ala Ala Leu 545 550 555 560 Asn Arg Met Asn Glu Thr Glu Ala Ala Arg His Gln Arg Glu Ile Ala 565 570 575 Arg Ile Asn Ala Met Gln Tyr Ala Asp Gln Ala Val Arg Asp Ala Ala 580 585 590 Ile Gln Arg Glu Asn Glu Arg Tyr Glu Lys Ala Leu Ala Ser Gly Lys 595 600 605 Lys Lys Thr Arg Glu Thr Arg Asn Asp Glu Ala Thr Arg Leu Leu Leu 610 615 620 Gln Tyr Ser Gln Gln Gln Ala Gln Val Glu Gly Gln Ile Ala Ala Ala 625 630 635 640 Arg Gln Ser Ala Gly Ile Ala Thr Glu Arg Met Thr Glu Ala Arg Lys 645 650 655 Gln Leu Leu Ala Leu Gln Gln Arg Ile Ser Asp Leu Asp Gly Lys Lys 660 665 670 Leu Thr Ala Asp Glu Lys Ser Val Leu Ala Arg Lys Asp Glu Leu Ile 675 680 685 Gln Ala Leu Thr Leu Leu Asp Val Lys Gln Gln Glu Leu Gln Lys Gln 690 695 700 Thr Ala Leu Asn Glu Leu Lys Lys Lys Thr Ile Gln Leu Thr Ser Gln 705 710 715 720 Leu Ala Glu Glu Glu Arg Ala Gln Arg Gln Gln His Asp Leu Asp Ile 725 730 735 Ala Thr Val Gly Met Gly Asp Gln Gln Arg Gln Arg Tyr Gln Val Gln 740 745 750 Leu Ser Leu Arg Gln Lys Tyr Gln Gln Gln Leu Glu Gln Leu Arg Arg 755 760 765 Asp Ser Glu Gln Lys Gly Thr Tyr Asn Thr Asp Asp Tyr Arg Lys Ala 770 775 780 Glu Gln Ala Leu Thr Glu Ser Leu Asn Arg Gln Leu Asn Glu Asn Arg 785 790 795 800 Arg Tyr Trp Gln Gln Leu Glu Val Val Gln Gly Asn Trp Lys Asn Gly 805 810 815 Val Leu Arg Ala Phe Gln Asp Phe Thr Val Asp Ala Asp Asn Thr Ala 820 825 830 Glu Thr Ala Glu Gln Val Phe Ser Ser Ala Phe Ser Asn Met Gly Asn 835 840 845 Gly Leu Ala Thr Phe Val Thr Thr Gly Lys Leu Asn Phe Lys Ser Phe 850 855 860 Thr Ser Ser Val Leu Ser Asp Met Ala Lys Ile Leu Ala Gln Ala Thr 865 870 875 880 Met Met Lys Ser Ile Lys Gly Ile Gly Ser Val Leu Gly Phe Asp Leu 885 890 895 Ser Ser Leu Ser Leu Asn Ala Asn Gly Gly Ile Tyr Gln Ser Ala Asp 900 905 910 Leu Ser Arg Tyr Ser Gly Thr Val Val Asn Arg Pro Thr Phe Phe Ala 915 920 925 Phe Ala Lys Gly Ala Gly Val Met Gly Glu Ala Gly Pro Glu Ala Ile 930 935 940 Leu Pro Leu Arg Arg Gly Ala Asp Gly Lys Leu Gly Val Val Ala Asp 945 950 955 960 Ile Gly Gly Ser Gly Met Ala Met Phe Ser Pro Gln Tyr Asn Ile Glu 965 970 975 Ile Asn Asn Asp Gly Thr Asn Gly Gln Ile Gly Pro Ala Ala Leu Lys 980 985 990 Ala Val Tyr Asp Leu Gly Lys Lys Ala Ala Ala Asp Phe Met Gln Gln 995 1000 1005 Gln Ala Arg Asp Gly Gly Arg Leu Ser Gly Ala Tyr Arg * 1010 1015 1020 <210> 965 <211> 110 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25200..25529) <400> 965 Met Gln Phe Val Met Arg Leu Ala Arg Glu Phe Arg Arg Ala Asp Trp 1 5 10 15 Arg Arg Met Leu Ser Glu Met Ser Ala Thr Glu Leu Gly Glu Trp Gly 20 25 30 Asp Tyr Phe Arg Met Gln Ser Phe Ser Asp Val Trp Met Asp Ala Gln 35 40 45 Phe Ala Ser Leu Lys Ala Leu Ile Val Arg Met Val Ser Gly Ser Ser 50 55 60 Asp Ala Ala Val Ala Asp Phe Ser Leu Leu Pro Glu Glu Asn Gly Ile 65 70 75 80 Pro Glu Arg Thr Asp Glu Glu Leu Met His Leu Gly Glu Gly Ile Ser 85 90 95 Gly Gly Val Arg Tyr Gly Pro Asp Ser Gln Pro Gly His 100 105 <210> 966 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25539..26237) <400> 966 Met Gln Asp Ile Pro Gln Glu Thr His His Glu Thr Thr Arg Leu Thr 1 5 10 15 Gln Ser Ala Gln Ala Val Leu Trp Glu Ile Asp Leu Thr Glu Val Gly 20 25 30 Gly Glu Arg Tyr Phe Phe Cys Asn Glu Gln Asn Glu Lys Gly Glu Pro 35 40 45 Val Thr Trp Gln Gly Arg Gln Tyr Gln Ala Tyr Pro Ile Gln Gly Thr 50 55 60 Gly Phe Glu Leu Asn Gly Lys Gly Ser Ser Ala Arg Pro Thr Leu Thr 65 70 75 80 Val Ser Asn Leu His Gly Met Val Thr Gly Met Ala Glu Asp Leu Gln 85 90 95 Ser Leu Val Gly Gly Thr Val Val Arg Arg Lys Val Tyr Ala Arg Phe 100 105 110 Leu Asp Ala Val Asn Phe Val Asn Gly Asn Ser Asp Ala Asp Pro Glu 115 120 125 Gln Glu Val Ile Ser Arg Trp Arg Ile Glu Gln Cys Ser Glu Leu Ser 130 135 140 Ala Val Ser Ala Ser Phe Val Leu Ser Thr Pro Thr Glu Thr Asp Gly 145 150 155 160 Ala Val Phe Pro Gly Arg Ile Met Leu Ala Asn Thr Cys Thr Trp Thr 165 170 175 Tyr Arg Gly Asp Glu Cys Gly Tyr His Gly Pro Ala Val Ala Asp Glu 180 185 190 Tyr Asp Gln Pro Thr Ser Asp Ile Thr Lys Asp Lys Cys Ser Lys Cys 195 200 205 Leu Ser Gly Cys Lys Phe Arg Asn Asn Val Gly Asn Phe Gly Gly Phe 210 215 220 Leu Ser Ile Asn Lys Leu Ser Gln * 225 230 <210> 967 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26387..26986) <400> 967 Met Ser Pro Glu Asp Trp Leu Gln Ala Glu Met Gln Gly Glu Ile Val 1 5 10 15 Ala Leu Val His Ser His Pro Gly Gly Leu Pro Trp Leu Ser Glu Ala 20 25 30 Asp Arg Arg Leu Gln Val Gln Ser Asp Leu Pro Trp Trp Leu Val Cys 35 40 45 Arg Gly Thr Ile His Lys Phe Arg Cys Val Pro His Leu Thr Gly Arg 50 55 60 Arg Phe Glu His Gly Val Thr Asp Cys Tyr Thr Leu Phe Arg Asp Ala 65 70 75 80 Tyr His Leu Ala Gly Ile Glu Met Pro Asp Phe His Arg Glu Asp Asp 85 90 95 Trp Trp Arg His Gly Gln Asn Leu Tyr Leu Asp Asn Leu Glu Ala Thr 100 105 110 Gly Leu Tyr Gln Val Pro Leu Ser Ser Ala Gln Pro Gly Asp Val Leu 115 120 125 Leu Cys Cys Phe Gly Ser Ser Val Pro Asn His Ala Ala Ile Tyr Cys 130 135 140 Gly Asp Gly Glu Leu Leu His His Ile Pro Glu Gln Leu Ser Lys Arg 145 150 155 160 Glu Arg Tyr Thr Asp Lys Trp Gln Arg Arg Thr His Ser Leu Trp Arg 165 170 175 His Arg Ala Trp Arg Ala Ser Ala Phe Thr Gly Ile Cys Asn Asp Leu 180 185 190 Ala Ala Ala Ser Thr Phe Val * 195 <210> 968 <211> 216 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26884..27531) <400> 968 Met Ala Ala Thr His Thr Leu Pro Leu Ala Ser Pro Gly Met Ala Arg 1 5 10 15 Ile Cys Leu Tyr Gly Asp Leu Gln Arg Phe Gly Arg Arg Ile Asp Leu 20 25 30 Arg Val Lys Thr Gly Ala Glu Ala Ile Arg Ala Leu Ala Met Gln Ile 35 40 45 Pro Ala Phe Arg Gln Lys Leu Ser Asp Gly Trp Tyr Leu Val Arg Ile 50 55 60 Ala Gly Arg Asp Thr Gly Glu Asn Glu Leu Ser Ala Arg Leu Asn Glu 65 70 75 80 Pro Leu Ala Asn Gly Ala Val Ile His Ile Val Pro Arg Leu Ala Gly 85 90 95 Ala Lys Ser Gly Gly Val Phe Gln Ala Val Leu Gly Ala Ala Leu Ile 100 105 110 Ala Val Ala Trp Trp Asn Pro Val Gly Trp Leu Gly Ala Ala Ala Val 115 120 125 Ser Gly Met Tyr Ala Ala Gly Ala Ser Met Ile Leu Gly Gly Val Ala 130 135 140 Gln Met Leu Ala Pro Lys Ala Arg Thr Pro Arg Thr Gln Thr Thr Asp 145 150 155 160 Asn Gly Lys Gln Asn Thr Tyr Phe Ser Ser Leu Asp Asn Met Val Ala 165 170 175 Gln Gly Asn Val Leu Pro Val Leu Tyr Gly Glu Met Arg Val Gly Ser 180 185 190 Arg Val Val Ser Gln Glu Ile Ser Thr Ala Asp Glu Gly Asp Gly Gly 195 200 205 Gln Val Val Val Ile Gly Arg * 210 215 <210> 969 <211> 1138 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27592..31005) <400> 969 Met Gly Lys Gly Ser Ser Lys Gly His Thr Pro Arg Glu Ala Lys Asp 1 5 10 15 Asn Leu Lys Ser Thr Gln Leu Leu Ser Val Ile Asp Ala Ile Ser Glu 20 25 30 Gly Pro Ile Glu Gly Pro Val Asp Gly Leu Lys Ser Val Leu Leu Asn 35 40 45 Ser Thr Pro Val Leu Asp Ser Glu Gly Asn Thr Asn Ile Ser Gly Val 50 55 60 Thr Val Val Phe Arg Ala Gly Glu Gln Glu Gln Thr Pro Pro Glu Gly 65 70 75 80 Phe Glu Ser Ser Gly Ser Glu Thr Val Leu Gly Thr Glu Val Lys Tyr 85 90 95 Asp Thr Pro Ile Thr Arg Thr Ile Thr Ser Ala Asn Ile Asp Arg Leu 100 105 110 Arg Phe Thr Phe Gly Val Gln Ala Leu Arg Glu Thr Thr Ser Lys Gly 115 120 125 Asp Arg Asn Pro Ser Glu Val Arg Leu Leu Val Gln Ile Gln Arg Asn 130 135 140 Gly Gly Trp Val Thr Glu Lys Asp Ile Thr Ile Lys Gly Lys Thr Thr 145 150 155 160 Ser Gln Tyr Leu Ala Ser Val Val Val Asp Asn Leu Pro Pro Arg Pro 165 170 175 Phe Asn Ile Arg Met Arg Arg Met Thr Pro Asp Ser Thr Thr Asp Gln 180 185 190 Leu Gln Asn Lys Thr Leu Trp Ser Ser Tyr Thr Glu Ile Ile Asp Val 195 200 205 Lys Gln Cys Tyr Pro Asn Thr Ala Leu Val Gly Val Gln Val Asp Ser 210 215 220 Glu Gln Phe Gly Ser Gln Gln Val Ser Arg Asn Tyr His Leu Arg Gly 225 230 235 240 Arg Ile Leu Gln Val Pro Ser Asn Tyr Asp Pro Glu Lys Arg Thr Tyr 245 250 255 Ser Gly Ile Trp Asp Gly Thr Leu Lys Pro Ala Tyr Ser Asn Asn Met 260 265 270 Ala Trp Cys Leu Trp Asp Met Leu Thr His Pro Arg Tyr Gly Met Gly 275 280 285 Lys Arg Leu Gly Ala Ala Asp Val Asp Lys Trp Ala Leu Tyr Val Ile 290 295 300 Gly Gln Tyr Cys Asp Gln Ser Val Pro Asp Gly Phe Gly Gly Thr Glu 305 310 315 320 Pro Arg Ile Thr Cys Asn Ala Tyr Leu Thr Thr Gln Arg Lys Ala Trp 325 330 335 Asp Val Leu Ser Asp Phe Cys Ser Ala Met Arg Cys Met Pro Val Trp 340 345 350 Asn Gly Gln Thr Leu Thr Phe Val Gln Asp Arg Pro Ser Asp Lys Val 355 360 365 Trp Thr Tyr Asn Arg Ser Asn Val Val Met Pro Asp Asp Gly Ala Pro 370 375 380 Phe Arg Tyr Ser Phe Ser Ala Leu Lys Asp Arg His Asn Ala Val Glu 385 390 395 400 Val Asn Trp Thr Asp Pro Asp Asn Gly Trp Glu Thr Ala Thr Glu Leu 405 410 415 Val Glu Asp Thr Gln Ala Ile Ala Arg Tyr Gly Arg Asn Val Thr Lys 420 425 430 Met Asp Ala Phe Gly Cys Thr Ser Arg Gly Gln Ala His Arg Ala Gly 435 440 445 Leu Trp Leu Ile Lys Thr Glu Leu Leu Glu Thr Gln Thr Val Asp Phe 450 455 460 Ser Val Gly Ala Glu Gly Leu Arg His Val Pro Gly Asp Val Ile Glu 465 470 475 480 Ile Cys Asp Asp Asp Tyr Ala Gly Ile Ser Ile Gly Gly Arg Val Leu 485 490 495 Ala Val Asn Ser Gln Thr Arg Thr Leu Thr Leu Asp Arg Glu Ile Thr 500 505 510 Leu Pro Ser Ser Gly Thr Thr Leu Ile Ser Leu Val Asp Gly Ser Gly 515 520 525 Asn Pro Val Ser Val Glu Val Gln Ser Val Thr Asp Gly Val Lys Val 530 535 540 Lys Val Ser Arg Val Pro Asp Gly Val Ala Glu Tyr Ser Val Trp Gly 545 550 555 560 Leu Lys Leu Pro Thr Leu Arg Gln Arg Leu Phe Arg Cys Val Ser Ile 565 570 575 Arg Glu Asn Asp Asp Gly Thr Tyr Ala Ile Thr Ala Val Gln His Val 580 585 590 Pro Glu Lys Glu Gly Ile Val Asp Asn Gly Ala His Phe Asp Gly Asp 595 600 605 Gln Ser Ser Thr Val Asn Gly Val Thr Pro Pro Ala Val Gln His Leu 610 615 620 Thr Ala Glu Val Ser Ala Asp Ser Gly Glu Tyr Gln Val Leu Ala Arg 625 630 635 640 Trp Asp Thr Pro Lys Val Val Lys Gly Val Ser Phe Leu Leu Arg Leu 645 650 655 Thr Val Ala Ala Asp Asp Gly Ser Glu Arg Leu Val Ser Thr Ala Arg 660 665 670 Thr Thr Glu Thr Thr Tyr Arg Phe Thr Gln Leu Ala Leu Gly Asn Tyr 675 680 685 Arg Leu Thr Val Arg Ala Val Asn Ala Trp Gly Gln Gln Gly Asp Pro 690 695 700 Ala Ser Val Ser Phe Arg Ile Ala Ala Pro Ala Ala Pro Ser Gln Ile 705 710 715 720 Glu Leu Thr Pro Gly Tyr Phe Gln Ile Thr Ala Thr Pro His Leu Ala 725 730 735 Val Tyr Asp Pro Thr Val Gln Phe Glu Phe Trp Phe Ser Glu Thr Arg 740 745 750 Ile Ala Asp Ile Arg Gln Val Glu Thr Ser Ala Arg Tyr Leu Gly Thr 755 760 765 Ala Leu Tyr Trp Ile Ala Ala Ser Ile Asn Ile Lys Pro Gly His Asp 770 775 780 Tyr Tyr Phe Tyr Ile Arg Ser Val Asn Thr Val Gly Lys Ser Ala Phe 785 790 795 800 Val Glu Ala Val Gly Arg Ala Ser Asp Asp Ala Glu Gly Tyr Leu Asp 805 810 815 Phe Phe Lys Gly Lys Ile Thr Glu Ser His Leu Gly Lys Glu Leu Leu 820 825 830 Glu Lys Val Asp Leu Thr Glu Asp Asn Ala Ser Arg Leu Asp Glu Phe 835 840 845 Ser Lys Glu Trp Lys Asp Ala Asn Asp Lys Trp Asn Ala Met Trp Gly 850 855 860 Val Lys Ile Glu Gln Thr Lys Asp Gly Lys His Tyr Val Ala Gly Ile 865 870 875 880 Gly Leu Ser Met Glu Asp Thr Glu Glu Gly Lys Leu Ser Gln Phe Leu 885 890 895 Val Ala Ala Asn Arg Ile Ala Phe Ile Asp Pro Ala Asn Gly Asn Glu 900 905 910 Thr Pro Met Phe Val Ala Gln Gly Asn Gln Ile Phe Met Asn Asp Val 915 920 925 Phe Leu Lys Arg Leu Thr Ala Pro Thr Ile Thr Ser Gly Gly Asn Pro 930 935 940 Pro Val Phe Ser Leu Thr Ser Asp Gly Lys Leu Thr Ala Lys Asn Ala 945 950 955 960 Asp Ile Ser Gly Ser Val Asn Ala Asn Ser Gly Thr Leu Asn Asn Val 965 970 975 Thr Val Asn Glu Asn Cys Thr Ile Lys Gly Met Leu Glu Ala Thr Gln 980 985 990 Val Arg Gly Asp Phe Val Lys Ala Val Ser Lys Ser Phe Pro Lys Gln 995 1000 1005 Ala Gly Thr Trp Gly Asn Thr Glu Thr Pro Asn Gly Thr Val Thr Val 1010 1015 1020 Thr Ile Ser Asp Asp His Asn Phe Asp Arg Gln Ile Ile Ile Pro Pro 1025 1030 1035 1040 Ile Ile Phe Asn Gly Ile Ala Tyr Ser Asp Pro Gly Ser Gly Asn Asn 1045 1050 1055 Pro Gly Gly Thr Arg Tyr Thr Gly Tyr Gly Phe Glu Val Arg Lys Asn 1060 1065 1070 Gly Val Leu Ile Ala Ser Arg Glu Thr Lys Gly Ala Ile Pro Gly Ser 1075 1080 1085 Tyr Ser Ala Val Ile Asp Met Pro Ser Gly Arg Gly Ser Val Thr Leu 1090 1095 1100 Glu Phe Lys Val Phe His Lys Gly Asn Gln Arg Ala Gly Asn Ile Thr 1105 1110 1115 1120 Asp Cys Thr Val Ile Val Thr Lys Lys Ala Ala Ser Gly Ile Ser Ile 1125 1130 1135 Arg * <210> 970 <211> 200 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31076..31675) <400> 970 Met Arg Lys Val Cys Ala Ala Ile Leu Ser Ala Ala Ile Cys Leu Ala 1 5 10 15 Val Ser Gly Val Pro Ala Trp Ala Ser Glu His Gln Ser Thr Leu Ser 20 25 30 Ala Gly Tyr Leu His Ala Ser Thr Asp Ala Pro Gly Ser Asp Asp Leu 35 40 45 Asn Gly Ile Asn Val Lys Tyr Arg Tyr Glu Phe Thr Asp Thr Leu Gly 50 55 60 Leu Ile Thr Ser Phe Ser Tyr Ala Asn Ala Glu Asp Glu Gln Lys Thr 65 70 75 80 His Tyr Ser Asp Thr Arg Trp His Glu Asp Tyr Val Arg Asn Arg Trp 85 90 95 Phe Ser Val Met Ala Gly Pro Ser Val Arg Val Asn Glu Trp Phe Ser 100 105 110 Ala Tyr Ala Met Ala Gly Val Ala Tyr Ser Arg Val Ser Thr Phe Ser 115 120 125 Gly Asp Tyr Phe Arg Val Thr Asp Asn Lys Arg Lys Thr His Asp Val 130 135 140 Leu Thr Gly Ser Asp Asp Ala Arg Tyr Ser Asn Thr Ser Leu Ala Trp 145 150 155 160 Gly Ala Gly Val Gln Phe Asn Pro Thr Glu Ser Val Ala Val Asp Val 165 170 175 Ala Tyr Glu Gly Ser Gly Ser Gly Asp Trp Arg Thr Asp Gly Phe Ile 180 185 190 Val Gly Val Gly Tyr Lys Phe * 195 <210> 971 <211> 439 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31735..33051) <400> 971 Met Ala Ala Val Gln Ile Ser Gly Val Leu Lys Asp Gly Ala Gly Lys 1 5 10 15 Pro Ile Gln Asn Cys Thr Ile Gln Leu Lys Ala Arg Arg Asn Ser Thr 20 25 30 Thr Val Val Val Asn Thr Val Ala Ser Glu Asn Pro Asp Glu Ala Gly 35 40 45 Arg Tyr Ser Met Asp Val Glu Tyr Gly Gln Tyr Ser Val Thr Leu Leu 50 55 60 Val Glu Gly Phe Pro Pro Ser His Ala Gly Thr Ile Ser Val Tyr Glu 65 70 75 80 Asp Ser Gln Pro Gly Thr Leu Asn Asp Phe Leu Gly Ala Met Thr Glu 85 90 95 Asp Asp Ala Arg Pro Glu Ala Leu Arg Arg Phe Glu Gln Met Val Glu 100 105 110 Glu Ala Ala Arg His Ala Glu Glu Ala Lys Lys Asn Ala Gly Glu Ala 115 120 125 Glu Thr Ser Ala Arg Asn Ala Gly Ile Ser Ala Ser Lys Ala Glu Ala 130 135 140 Ser Ala Ala Asn Ala Asp Thr Ser Ala Glu Asp Ala Ser Glu Ser Ala 145 150 155 160 Arg Gln Ala Ala Glu Ser Ala Ala Ser Ala Lys Lys Ser Glu Glu Ala 165 170 175 Ser Ser Ser Ser Ala Ser Glu Ala Ala Gln Lys Ala Ser Glu Ser Leu 180 185 190 Gln Ser Ala Thr Asp Ala Glu Leu Ser Lys Lys Thr Ala Glu Ser Ala 195 200 205 Ala Gly Asn Ala Ala Arg Asp Ala Thr Thr Ser Thr Glu Lys Ala Arg 210 215 220 Glu Ser Ala Glu Ser Ala Gln Ser Ala Glu Gln Ser Arg Ile Ala Ala 225 230 235 240 Glu Asp Ala Val Asn Arg Ile Pro Thr Val Val Gly Pro Pro Gly Pro 245 250 255 Lys Gly Glu Pro Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp Lys 260 265 270 Gly Glu Arg Gly Asp Thr Gly Pro Ala Gly Ala Thr Gly Glu Arg Gly 275 280 285 Pro Gly Gly Asp Thr Gly Pro Ala Gly Pro Gln Gly Pro Lys Gly Asp 290 295 300 Arg Gly Glu Arg Gly Glu Thr Gly Leu Thr Gly Ser Thr Gly Pro Gln 305 310 315 320 Gly Pro Lys Gly Asp Thr Gly Ala Thr Gly Pro Ala Gly Pro Gln Gly 325 330 335 Pro Lys Gly Glu Thr Gly Ala Ala Gly Pro Val Gly Ala Thr Gly Pro 340 345 350 Gln Gly Ala Lys Gly Asp Pro Gly Glu Thr Gln Ile Arg Phe Arg Leu 355 360 365 Gly Pro Met Arg Ile Ile Glu Thr Asn Ser Tyr Gly Trp Phe Pro Gly 370 375 380 Thr Asp Gly Ala Leu Ile Thr Gly Leu Thr Phe Leu Asp Pro Lys Asp 385 390 395 400 Ala Thr Gln Val Gln Gly Met Phe Gln His Leu Gln Val Arg Phe Gly 405 410 415 Asp Gly Pro Trp Gln Asp Val Lys Gly Leu Asp Glu Val Gly Ser Asp 420 425 430 Thr Gly Arg Thr Gly Glu * 435 <210> 972 <211> 103 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33014..33322) <400> 972 Met Lys Trp Ala Val Ile Gln Ala Glu Leu Glu Asn Asp Met Asn Ile 1 5 10 15 Leu Arg Lys Leu Met Gln Ser Leu Cys Gly Cys Gly Lys His Asp Asp 20 25 30 Cys Glu Asn Gly Arg Ser Leu Thr Ala Gln Leu Arg Leu Gly Pro Ala 35 40 45 Asp Ile Leu Glu Ser Asp Glu Asn Gly Ile Ile Pro Glu Gln Asp Arg 50 55 60 Val Ile Thr Gln Val Val Ile Leu Asp Ala Asp Lys Lys Gln Ile Gln 65 70 75 80 Cys Val Val Arg Pro Leu Gln Ile Leu Arg Ala Asp Gly Thr Trp Glu 85 90 95 Asn Ile Gly Gly Met Lys * 100 <210> 973 <211> 327 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33499..34479) <400> 973 Met Leu Ser Pro Ile Arg Thr Thr Phe His Asn Ser Val Asn Ile Val 1 5 10 15 Gln Ser Ser Pro Cys Gln Thr Val Ser Phe Ala Gly Lys Glu Tyr Glu 20 25 30 Leu Lys Val Ile Asp Glu Lys Thr Pro Ile Leu Phe Gln Trp Phe Glu 35 40 45 Pro Asn Pro Glu Arg Tyr Lys Lys Asp Glu Val Pro Ile Val Asn Thr 50 55 60 Lys Gln His Pro Tyr Leu Asp Asn Val Thr Asn Ala Ala Arg Ile Glu 65 70 75 80 Ser Asp Arg Met Ile Gly Ile Phe Val Asp Gly Asp Phe Ser Val Asn 85 90 95 Gln Lys Thr Ala Phe Ser Lys Leu Glu Arg Asp Phe Glu Asn Val Met 100 105 110 Ile Ile Tyr Arg Glu Asp Val Asp Phe Ser Met Tyr Asp Arg Lys Leu 115 120 125 Ser Asp Ile Tyr His Asp Ile Ile Cys Glu Gln Arg Leu Arg Thr Glu 130 135 140 Asp Lys Arg Asp Glu Tyr Leu Leu Asn Leu Leu Glu Lys Glu Leu Arg 145 150 155 160 Glu Ile Ser Lys Ala Gln Asp Ser Leu Ile Ser Met Tyr Ala Lys Lys 165 170 175 Arg Asn His Ala Trp Phe Asp Phe Phe Arg Asn Leu Ala Leu Leu Lys 180 185 190 Ala Gly Glu Ile Phe Arg Cys Thr Tyr Asn Thr Lys Asn His Gly Ile 195 200 205 Ser Phe Gly Glu Gly Cys Ile Tyr Leu Asp Met Asp Met Ile Leu Thr 210 215 220 Gly Lys Leu Gly Thr Ile Tyr Ala Pro Asp Gly Ile Ser Met His Val 225 230 235 240 Asp Arg Arg Asn Asp Ser Val Asn Ile Glu Asn Ser Ala Ile Ile Val 245 250 255 Asn Arg Ser Asn His Pro Ala Leu Leu Glu Gly Leu Ser Phe Met His 260 265 270 Ser Lys Val Asp Ala His Pro Tyr Tyr Asp Gly Leu Gly Lys Gly Val 275 280 285 Lys Lys Tyr Phe Asn Phe Thr Pro Leu His Asn Tyr Asn His Phe Cys 290 295 300 Asp Phe Ile Glu Phe Asn His Pro Asn Ile Ile Met Asn Thr Ser Gln 305 310 315 320 Tyr Thr Cys Ser Ser Trp 325 <210> 974 <211> 331 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34540..35532) <400> 974 Met Lys Ile Pro Ser Leu Gln Ser Asn Phe Asn Phe Ser Ala Pro Ala 1 5 10 15 Gly Tyr Ser Ala Pro Ile Ala Pro Asn Arg Ala Glu Asn Ala Tyr Ala 20 25 30 Asp Tyr Val Leu Asp Ile Gly Lys Arg Ile Pro Leu Ser Ala Ala Asp 35 40 45 Leu Ser Asn Val Tyr Glu Ser Val Ile Arg Ala Val His Asp Ser Arg 50 55 60 Ser Arg Leu Ile Asp Gln His Thr Val Asp Met Ile Gly Asn Thr Val 65 70 75 80 Leu Asp Ala Leu Ser Arg Ser Gln Thr Phe Arg Asp Ala Val Ser Tyr 85 90 95 Gly Ile His Asn Glu Lys Val His Ile Gly Cys Ile Lys Tyr Arg Asn 100 105 110 Glu Tyr Glu Leu Asn Glu Glu Ser Ser Val Lys Ile Asp Asp Ile Gln 115 120 125 Ser Leu Thr Cys Asn Glu Leu Tyr Glu Tyr Asp Val Gly Gln Glu Pro 130 135 140 Ile Phe Pro Ile Cys Glu Ala Gly Glu Asn Asp Asn Glu Glu Pro Tyr 145 150 155 160 Val Ser Phe Ser Val Ala Pro Asp Thr Asp Ser Tyr Glu Met Pro Ser 165 170 175 Trp Gln Glu Gly Leu Ile His Glu Ile Ile His His Val Thr Gly Ser 180 185 190 Ser Asp Pro Ser Gly Asp Ser Asn Ile Glu Leu Gly Pro Thr Glu Ile 195 200 205 Leu Ala Arg Arg Val Ala Gln Glu Leu Gly Trp Ser Val Pro Asp Phe 210 215 220 Lys Gly Tyr Ala Glu Pro Glu Arg Glu Ala His Leu Arg Leu Arg Asn 225 230 235 240 Leu Asn Ala Leu Arg Gln Ala Ala Met Arg His Glu Glu Asn Glu Arg 245 250 255 Ala Phe Phe Glu Arg Leu Gly Thr Ile Ser Asp Arg Tyr Glu Ala Ser 260 265 270 Pro Asp Phe Thr Glu Tyr Ser Ala Val Ser Asn Ile Gly Tyr Gly Phe 275 280 285 Ile Gln Gln His Asp Phe Pro Gly Leu Ala Ile Asn Asp Asn Leu Gln 290 295 300 Asp Ala Asn Gln Ile Gln Leu Tyr His Gly Ala Pro Tyr Ile Phe Thr 305 310 315 320 Phe Gly Asp Val Asp Lys His Asn Gln Gln * 325 330 <210> 975 <211> 294 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(36360..37241) <400> 975 Met Leu Ser Pro Tyr Ser Val Asn Leu Gly Cys Ser Trp Asn Ser Leu 1 5 10 15 Thr Arg Asn Leu Thr Ser Pro Asp Asn Arg Val Leu Ser Ser Val Arg 20 25 30 Asp Ala Ala Val His Ser Asp Asn Gly Ala Gln Val Lys Val Gly Asn 35 40 45 Arg Thr Tyr Arg Val Val Ala Thr Asp Asn Lys Phe Cys Val Thr Arg 50 55 60 Glu Ser His Ser Gly Cys Phe Thr Asn Leu Leu His Arg Leu Gly Trp 65 70 75 80 Pro Lys Gly Glu Ile Ser Arg Lys Ile Glu Val Met Leu Asn Ala Ser 85 90 95 Pro Val Ser Ala Ala Met Glu Arg Gly Ile Val His Ser Asn Arg Pro 100 105 110 Asp Leu Pro Pro Val Asp Tyr Ala Pro Pro Glu Leu Pro Ser Val Asp 115 120 125 Tyr Asn Arg Leu Ser Val Pro Gly Asn Val Ile Gly Lys Gly Gly Asn 130 135 140 Ala Val Val Tyr Glu Asp Ala Glu Asp Ala Thr Lys Val Leu Lys Met 145 150 155 160 Phe Thr Thr Ser Gln Ser Asn Glu Glu Val Thr Ser Glu Val Arg Cys 165 170 175 Phe Asn Gln Tyr Tyr Gly Ala Gly Ser Ala Glu Lys Ile Tyr Gly Asn 180 185 190 Asn Gly Asp Ile Ile Gly Ile Arg Met Asp Lys Ile Asn Gly Glu Ser 195 200 205 Leu Leu Asn Ile Ser Ser Leu Pro Ala Gln Ala Glu His Ala Ile Tyr 210 215 220 Asp Met Phe Asp Arg Leu Glu Gln Lys Gly Ile Leu Phe Val Asp Thr 225 230 235 240 Thr Glu Thr Asn Val Leu Tyr Asp Arg Ala Lys Asn Glu Phe Asn Pro 245 250 255 Ile Asp Ile Ser Ser Tyr Asn Val Ser Asp Arg Ser Trp Ser Glu Ser 260 265 270 Gln Ile Met Gln Ser Tyr His Gly Gly Lys Gln Asp Leu Ile Ser Val 275 280 285 Val Leu Ser Lys Ile * 290 <210> 976 <211> 45 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37276..37410) <400> 976 Met Glu Leu Val Thr Asn Cys Val Val Gly Asn Ser Trp Arg Ile Thr 1 5 10 15 Glu Met Gly Asn Val Ala Glu Asp Trp Gln Met Ala Met Ile Arg Phe 20 25 30 Ile Ile Gly Phe Gly Asp Arg Leu Asp Gly His Phe * 35 40 <210> 977 <211> 233 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(37472..38170) <400> 977 Met Arg Pro Thr Ser Leu Asn Leu Val Leu His Gln Ser Ser Arg Ser 1 5 10 15 Ser Ser Met Ser Asp Thr Asp Ile Glu Ser Leu Val Lys Ala Ser Ser 20 25 30 Val Gln Trp Ile Lys Asn Asn Pro Gln Leu Arg Phe Gln Gly Thr Asp 35 40 45 His Asn Ile Tyr Gln Gln Ile Glu Ala Ala Leu Asp Lys Ile Gly Ser 50 55 60 Thr Glu Thr Gly Arg Val Leu Leu Asn Ala Ile Glu Ser Ile Ser Arg 65 70 75 80 Leu Lys Ser Glu Thr Val Val Ile His Leu Asn Ser Ser Arg Leu Gly 85 90 95 Val Met Ala His Arg Asp Ile Asp Ala Glu Asn His Arg Gly Thr Gly 100 105 110 Ser Asp Phe His Cys Asn Leu Asn Ala Val Glu Tyr Pro Cys Gly Glu 115 120 125 Gly Ile Ser Val Val Asp Phe His Ala Thr Ile Val Phe His Glu Leu 130 135 140 Leu His Val Phe His Asn Leu Asn Gly Glu Arg Leu Lys Val Glu Ser 145 150 155 160 Ser Arg Ala Glu Ser Gln Lys Tyr Ser Pro Leu Leu Leu Glu Glu Ala 165 170 175 Arg Thr Val Gly Leu Gly Ala Phe Ser Glu Glu Val Leu Ser Glu Asn 180 185 190 Lys Phe His Glu Glu Ile Gly Met Pro Arg Arg Thr Ser Tyr Pro His 195 200 205 Asp Ser Ala Leu Ile His Asp Asp Asn Thr Val Ser Leu Gly Phe Gln 210 215 220 Gln Val Arg Leu His Pro Leu Leu * 225 230 <210> 978 <211> 35910 <212> DNA <213> Escherichia coli O157:H7 <400> 978 tttccgccgg ctggaataac aaaaacgagc aataaagaac tatcaaatga ccatgttacg 60 gaagcgcaac tgtttaattt gaaacaaaaa acatatgtat cgatggtgaa agacttggtg 120 agtcgattcc agtaatcgtt attgttatgc tgccgcctgt agtttagggt ggcagcaaac 180 aggagttgag tatttctata atgtaaatat gattgttttt ataaagttat aatatatatt 240 accagtgtat tgcatgtgag ttattttttt aattcttcat aaattaaaat agtatcatct 300 gcaatggaaa gaattgctat tatctcttca tttttttata tttttctttt aatgtcttgt 360 ttctttcttt taatggagta cattcattaa taatatcatt cttagctgtc attgagtcag 420 tttcgatatc gaatgctaaa tctacaaagc aataatctac gtagaacata aatctacgta 480 tatcttccgg tatagcagtg gaaaaataac ggtattgcgt gtaagtggtt tgatcatcga 540 attcgtctga ttgtactgaa tatgtaaatg tggccagtat aaatagtaat gttaatctta 600 aatttataat aatcatttgc tggatatctc atctggattt tgaaagtcag aaatgtaagc 660 attgtttagt tgcatggctc ttattttgtt taactcagta tagcatggat atagccgaga 720 gaatgccagt cgccctactc tggcccccca ggttagagta aaagagcatt gagcaaatct 780 gtaacgtata aattccctat tagaagactc tagtcttttt aaagaaataa ctgcttcttt 840 tcttattgct tcgtcctcat cactattcca tttttgaatt ttctctttta tatttgcttc 900 tgctttttta agtgtaatag tgctcataat aaatgagttt ttaacacaat caataaattc 960 aagttcatca acaccactac attctttaga catggaaatg tcaaatgcca gaccttttgt 1020 acatgagaat gtcagcagta gaataattgt tatttttcgc attctcataa tactctgttt 1080 tttgtgagta atgtataaac gaactgaagt tttattgcat acttgggatc gccaccacca 1140 ttataattca tcgctacatt ttttattgtg ataggtttcc atccagtaat tattactttc 1200 atggatgctt tttgataata taaaatatct cccgggtgta ttttatcgag attttttcca 1260 ggattgtttt tcgttaagtt aggtatggtc gtttttctct cttttctgat gttgtcagcc 1320 aaatcgcctt tttggacaat ggcgctatat agagttgagt catattgatc gatagttgat 1380 tcttcctttg tattagaaag tttcatcatt aagtaagtaa ttgctgcttt gatattctct 1440 tctggagagc cagttatttg ttcttttgcc cagtaatttc tttctggatc ttttaaccca 1500 ttgaatgctt tgtttctcca ttgtggtggg gtaacaaggg ctgtagattt ttctccagag 1560 attaaagctg gcatcgcttt atctttccga aaacgaccaa tttgtaatgg ataaccattc 1620 cactgagaag tattttccgc atcgttttca gtccagagca tggcttttat tatataccaa 1680 tccaacggct gaaagtatgg agtgctggac aaatgaatgt tgatttcatt aacagatttt 1740 taaattaata agtcatattt attccattct ttatgattgc tcacaaatgc caactctctt 1800 atttttttcc atttaaaaaa atcactttca tcttctgtta ttcttgatgc gaaatcttgt 1860 cttagttgaa atgggaattt ttcattaaat aacgtactgt cagtgcttgt atttttgctt 1920 tcactgtctg atgttgaaga gtgtaaaata ttgttagcca ttataataat cccatatgtt 1980 tttaaaaaag acgatcttcc cataaactgt atgcactagt gccagcggaa caatgctccc 2040 atataattga ctcataactg aaagaaactg actcttcggg ttgaacgctg ttatcaacaa 2100 caatatgtga tatagagaca tgaatgtcgc ttatctttgc tccagttaat ttgattttat 2160 agaacagttc attaattcca aatttatttg tacgataaaa ggaaaaatca catgtcaata 2220 attcattgtc gcaaattgct ttgcctaata agggtgatgc tttatctata ggttttttta 2280 ttgtcaaatg atgatggttg acgttttgat ctcgatttaa tccatgcatg aattcataaa 2340 tcataatttg atcaatgtgt gctgtttgag ctttatttcc aatggatggt tgtgatgaac 2400 aaccacttga aatgagccct tgattatcac catttagtgt taaataaatt aaattcgcca 2460 tttaaaactc ctttgtattc atgaatgtta ttgaaattca atgctttttt tatcgtcggt 2520 atcgtattat tcttcagcag cagccagcgg cttaacacgc cttcgagtcg ctcattaatt 2580 tgtttttcca gcgcatctgt attctgcttc tgcgcacggg catcctggta ctgcgtcaac 2640 agagactcaa cgggtgtttc ctgccccagt ccccgctccg cctgccagat gacatttttg 2700 atataggaaa gggttagtcc ctctttctcg cgctgcatca ctagatctgc aaaagcatgt 2760 aagtcctggc gggtctgcaa ccagccacgc aactgcgggc tactctgtgc gcgggttttg 2820 agtgcctcat tccattgtgt cgaggcctgt tgctgttgca ggctttccgg ccagcgactg 2880 tcggcaacac gcatcatctg catcccggtt tccagcggct gtaccgggga ggtatcaaga 2940 agttgttgca gcctgcgctc atagttttcg agttcaggtg aggccatcca caccgttgct 3000 gcgccctgag cggtgtcgtt aacctgtaac agttgctgct gcaccggata gacctgccac 3060 caccacaatg ctgaggcgac agccactgaa caggcgatcc ctgcgataaa ccctcttacc 3120 gtactgcctt gctttatcac actggcctgt gggggattct ctgtcagact gcgcacttcc 3180 actttcatct caggcaggcc gggcagggga ggcactaccg cttctggtgt ggaagatgcc 3240 tgtgtttccg gggcataaat cagcgttctg accgtggtct gtgcggcgtt ctcagtgtta 3300 ctcttcagct ggggttcaag ccgtttacgc gtgttctgca taaaatagag cagattctcc 3360 acgcgcggaa cgcgcttcag ttccacctgc tggagcttat cgcagataag ctgcaatgcc 3420 cgctctgtgc ggtagatcag tggtaggtcg gattccgcaa aggagatttg ctgacgcaga 3480 atattgccgg ttcgggagtt aaaccagtcc agcatttcag tacgcgccgg gccgccctgc 3540 ggccagaact tatcccagtc gtggcttacc attgccgcca gcagttccgc accttcgcag 3600 aatcccgcca gtccctgtgt ccgtgtccgg gcaagcgtat agtaggtggc ggtgtgtaaa 3660 tccacaccgt tggctttaaa aatcgccagc gccagcgact ccaccagttt ccagttcagc 3720 tcaggctgtg acgggtggct ggctttgttt atttcctcgc ggatggcgct gaattccggc 3780 agcccgcgcg ggtcactgcc ggtaacgata gtttgtgtca gtacgttact attcatccct 3840 gcctcctcag tacagtgtgt ctgacagacc aaactggctg aacaacccac cgctgaacgg 3900 gttatcttcc gtgtcggtat gcacacggta ggtcatcgcg ccaccgtcca cgctaaagcg 3960 cacggtaaag ttgccatcct gtactccggt cagttgtccg gccccgaaca ggcggaactg 4020 cgcccacggc ccgctgaagc tgatactgcg cggcgcgttg ccgctggtgc cgatgagcgt 4080 cagcttactt tcgttgcctt cgcgcatgtt gttaggccag accagatggg cggtatagtt 4140 acggccctgg ctgtaatcga ctaactgacc gtcaaggttc agtacactgc ggcgtttatt 4200 gcctgaaagc gataccgttt ccacggcaaa ggatgttccc agaccgttct gtttgctgaa 4260 gaagatgtca cggattttct gcgcagtttc cagttgcgca ataatatctt cgcgaataat 4320 gacgttgtta tcgccatcct ccagactcag gtcattatcg ataaacagct tcaggttctg 4380 ctggtagaag gtatccagta tgccatccgg tttaaagaag cgttcgaagg catccagtga 4440 ggcatcctgt gcagaacgcg gattaaacgg atagttattt gccagttgct cgttaaacgg 4500 tttcaccacg ctgtcgcgcc agtccacttc catataatgt acagcctcca ccatcaccac 4560 atgccaggcc tggtcagtca gtctgccaac ccagcggttg agcggagcag gcagcgtttt 4620 tgccatctgg cgggtggcga atatcggatc gctgctgttc tgatcaagcc gtaactgcac 4680 ggctttcagc gccgatttcc ctggtacagg cgcgttctgg attgccagca ggtagcggtg 4740 caactcggtg agttgctgat acacggcctg catcgtgctt tctttgtctt tctgtactgc 4800 cagggtaatg ttttccgggg cgaactcatg cccgagacgg gtgagtaact ggtagtccgg 4860 ctctgccagg gcctcatccc gttctttggc agagagtttt tcagaaaaga cgcctggctg 4920 tgtgttgtca cgcagcacgg tcagcgcccg ctgcaaaggc tggtcgccgc tgataacctg 4980 ctccagcgcc ccggtcagtt gtccgatgga ctcaaaattg cggatattca gattgtccat 5040 cccggcccgc caggtggcgg tgtagtcgct gatatactgc tcggtgagct ggcgctggat 5100 ttccgcgcgg tcggcgtcac tgtatttcac gctgcgggta aggttaagta cccaggaatc 5160 catcgccgtc agttcaacca gttcatcgcg ctgttttaca aaatagcttt gcaggccgta 5220 acgggtaaga aactgtggaa caaccagttt gttgtcatcg gcagatgtaa acacctggtc 5280 aaaggttggc cctacctggt cacgcagatt gaggtcggca ggaagaacgc ccagcgcccg 5340 cgttttcagg ctctggtaaa cccgctggta gacaggcagt ttgctcagtt ctttctgtgc 5400 tgataccacg ggcttgtcat atggcgtcca gcggctgatg gcgtcaccgt cgcccgcctg 5460 acgctctgcg tgccagtcag tatgagccag cgcgtagtca agatgggaca tcagttgtgc 5520 ctggatatcg cgctggccgt ggaacttttc gctccagcgt tttgccatat actgcttcac 5580 cacctcattg ttacgtccgc ttttgtcctc cagcattcgc atcacgcgca gcaccgcgag 5640 tttttcttca ctctccggcg gcgcggcatt catcgcttta accagcccgt taaacagcga 5700 gggcaggtaa cgttgctcca gcagttgcag ataggtctgt tccacataag gtccgatacg 5760 tcgtccctgg tacagtccca tatcggccag acggctgcgg tcgccccagt cgccataggc 5820 cagtgtggca tcgcgtaccg ggttcagcag cggcagttgc aggttgccgt agtcatcttc 5880 cccctgtgga ggcggcacat ccataaaggc tttggcctgc ttaagcacgg tgatgccgga 5940 ctgatagtta ccgttgtaat agtgatgcca gccggtgatg agcagcagtg ccgccacgcc 6000 gccggtggca gagaaaaccg tcaggcggcg acgggaacgc atcagccagg cgcggctctc 6060 cgttgccaga ttaggctctg cgagtaatgc ctgcgggaac aagctgcggg tgaaataagg 6120 cgcggtgtcc accagaggcc aggacgccag tgggttattg cccagtcggt actggcgggc 6180 ggcagactgg gtgaatatat catccatctg cccgcgctga agcgaagagg tgagatagac 6240 accacgcagc atcacgttca tattttcacc gtcaagcaga ccctcaagca gtgacaccag 6300 cggttcacgg cttccctgca tctggcggga aaaactgaat aaagacgcgc gggtgtgagt 6360 ctgggtgacc atcagatccg gcaacgccag attcattcga tccacccatg tctgccagaa 6420 agcattcaac tctgttcgcc agtcatcatt ttcatgggca cggcgggtga acgtgacgcc 6480 cagaatcgca tcgcgatcct gtctgttcag ggactggaac agggcggcaa aaccctgtaa 6540 taaatcaagc cgggtcagta ccacgtaaac cggtaactgg cagtgaagat gctggcgtat 6600 atcctgtaag cggctgcgca gcgtctgtaa cagatgctcg cggtggcgtt tgtctgcggt 6660 cagcagatcg ggtaaatcga gtgtcagaat aatcccgttc agcggctggc gcgcgcgctt 6720 ttctttcagc cagccgaggg catgttccca cagacggcga tgcaggatat ccgcatcagc 6780 gggagcgcag agtgtgccgt cgatatcaaa gatcaccgcc tgtttaccga catggggcgt 6840 aaggtacagg cgttgttctg tgccgcgcgc gccctccggg gcataaataa tgtctgacgg 6900 aaacccctcg cgcagcagtg tcgttttgcc actgcccgcc gggccgatga ccatatacca 6960 cggtaactgc cacaggaaac ggcggttgtc gagatggcgt tgcaggcgca gcagccagcg 7020 gtcaaggtaa cgctgctggg cgttcagctc cacactgagc ggatcaatgg cctcttcgcg 7080 ctgctgtttt tgctgttttt caagcagttg caggcgcttc attacccgga cggtaagcca 7140 caccagggca ataatccccc acgccgccgt tgccagccag cggttcgcca gtggtttgag 7200 ccactgttct tcatacagcg tccacgtcgg gcctttccac cagatccata ccagcagaaa 7260 aatccacgcc agtatcagca agcagaaaaa tccacgccag tatcagcagc cagaaagcgg 7320 agactttaaa ccggggcatc gccggtcgca gggctgattt gagtccgctg agtagtcggg 7380 gtgttggtaa tctgaacaca aaaactcctg ttctctttta ttgttctgcc gtgaattttt 7440 gttcaagctg cgtaagtaat gatggctccc agtcagacac catcatctga ctccctatca 7500 tcaacaacat ccggtactgt tgctgcgcaa gctgtatcag ccccgcctcc tccgtcaact 7560 gtgcggcaag gtactggcgg tgaaactgat cgcggggatc gccttcgggt agcatgtcca 7620 gatatcgcag cgccgcctcc agaccctgcc cagcaaaaca ggctctggct gcctgcgatt 7680 cctcaccgat ttgcgcaacc ggtgcaactt tgccgtcggg cgaagcagcc agccattgtt 7740 tcgtctgctc actgagaaac ggtgtgcggt cattaaacag cagcccggta agctggggca 7800 gacgctcaag gaagcggatg acctcatcgc ggatggtgtc tgccacctgt ttgtaaccca 7860 gacgcagtgc cgtctgtgca gaaagacagt gaccgtccag ccagtaagga gccagcaata 7920 cgcttttctc aacctgttgc cacagcgcca tatccgcgct ggcaagccgg gactggtaat 7980 ccgccaccat atcggcagag accgcagcca gtggggtacg tccatcgctt tccgcctggg 8040 gtgtactggt gatggattgc cacagggcat ggcggcgcag gcgatagccc tgcggcgagt 8100 ccggctggcg ttcacataaa atagccgcca cttttaacag cgtgtcgcgc caggctttgt 8160 cgtcgtgact gtcgatggcg atttggggag ccggagcact gggttgcgtc acgccgcttt 8220 cagacgtgac ggtggtttgt ggtgaactac cggaggccgc cggagtgggg accggagcag 8280 gagccgcacg attaaacgta cgctggtaca gggcaaaaag atcatcggta gcctgtgcca 8340 gttccgggac gttatgtgac tgccagcact gcgccagttt cgccagctca cccagcagag 8400 tatcgcgctg cgttgtggca gcgttttgtg aaaagccttc aataccgttt caaaacgttt 8460 aatgatctgg ctggcaaagc gttttttatg cgccatattc tgcggcgcgg ccacagtcca 8520 gtaatgttcc acgtatagcg ttagcaggtg cagtgccagc agtggatcac cggcatgttg 8580 cagggttctg agcaggtgtg ccagtagcct gaagtctttg ctttcagaag ccagaagctg 8640 tagccccctg cgttgtagtt cgggaatatc aagctgagcg tgggccagag accccagctt 8700 gacgatttcg ccgtcgatat actcccagtc cgggttgtca tctttcagcg ccgatgccag 8760 tttttcttcc ggcaggtttt ccagcaggtg cgatatccag acattcggat cgcgtaagtc 8820 cattgccata tttttattct cccgcccagt ggcaggcatc gcgcaggggg gcaatcgccc 8880 ttgccagccc gtcaatgtta aaggtcagct ttcctgcggc gttatctgcg ccggtatcca 8940 ctgtcagcgt ttttgcgccg aacagttgct taatttcatc aatcccggac agcccccggc 9000 tggactccag cagggtgccg ttctcgcgca caaaccagtg gctgcgcaat gcccggctgt 9060 cggcattcag agtgacggcg atatcatgga catccagagg gtgcatcagc gccacctgca 9120 tccgggtgat attgtccacg caactgaaca tcagcaccgg gcgcggcgga acatggccga 9180 tagccggggt ggttatcacc accgtcgggc gctcccccgg cacctgcgtc accagcagtt 9240 ctgtggtgtt gccctcgcgg cgtttttcct gctctgtggc gcgggtccag gcctcgccca 9300 caaaaccggc tttgaccagc gccccgtcaa accctgacgg ggacagcggt gccagcaggt 9360 ggtcatagca gtcaagccgc tccagcgccg cggactcccg ccgacaggac tgcatggcct 9420 gtaacgtggc tgtcgcatcc ggcggggtcg tggtggcgac ggcgaccgcc acaccggcca 9480 ttgacgatgc ttctgcgggc gcggcagtgg cgggtaagcc cgtcatcagg cccgcgataa 9540 accatcctgt ctgccggaaa acgcgcaacc tgctcataaa accgtttcat cctttgtgac 9600 ggactcgtcg ttctgagcat cttccacgtc tgccgtaaat gcgccgtcca ctgccgacaa 9660 ccgaatccgg gcaatcgccg tgttagccgc cattttctgc aacagcagca gcgagagcgg 9720 cggtagcatg tcgccatcga tgacagattc cagcatcctc gcgccgtttt ccgcgcgggt 9780 gacgcggctc atgatttcgt ccgtcacttc cggttcaatg accacttctg caccaaagcg 9840 actgcgcagc acgttatcca gacgggccag tttcccggcg ataatggtgg cgagcgtctc 9900 tttcgacagc ggcaggtacg gcaccacctc cattcgcgcc agcagggcag gtttaaagaa 9960 gtccgccagc accggataga gggcttcctg catggtttcc gggtcatccg cgtgttcgac 1002 0 aatcacctgg taaccgaggt tggaggtgag gaagaagacg atgtttttac agtcaatcag 1008 0 gcggccttcg ccgtcggcca tctcgccctt gtcaaacgcc tggtagaaca ggttgaggac 1014 0 atccgggtgc gctttttcca cttcatcgag cagcaccacc gagtagggtt tctggcggat 1020 0 ggcttcagtc agcacgccgc cttcgccata gccgacatag cccggagggg agccaatcag 1026 0 ccgcgaaacg gtgtgtttct cctggaactc ggacatattg atggtggtca ggtactggcg 1032 0 accgccgtag agcagctctg ccagttgcag gacggtttcg gttttaccca cgccgctggg 1038 0 gccagcgagc aggaacgcac cgagcgggcg tcccggacga cgcaggtcgg cgcgtgcggt 1044 0 cagtagatgc ttatgcaggc tggcaatcgc caggtcctgg cctttgatgg tgtcgcccag 1050 0 ccatttcggc aggtcggtga tgaccgacat ttcattctgc gacaggcggt tgagcggcac 1056 0 gccggtccat tcggcaatca ccgccgcaat ctgtttttta tcgacgtgcg gggagaccag 1062 0 caaccggtcg ttatgcaggg cgtccagttc ggcagtgagc tgggccagcc gctgtaccgg 1068 0 ggaaactgtt tcagcggtct cttccggctg ttctctgtcg gtctcatcag ccggtacggc 1074 0 accggtatta tcctgttctg actctgactc tgactctggc tgcgtatcct ccacagtatc 1080 0 tgcgtccggc aacggcgccg catcgtcctc tgccacgccc agtaactgct ggcgcagcgc 1086 0 gataatctcc cggaccagcg tctgctgctg gtgccaagcc gcttccagtt catccagcgc 1092 0 cgtcagcgtt tcatcatact gcaccagcac ctcggtcatc cgtgatgtgt cggtacgcag 1098 0 tccgatgcga agctcgcgct caagctggcg aatttccgcc tcctgctggt ggctcagagt 1104 0 ggtcagcgcc gagatttgct tcggcggcga cgacaggttg atggccacac gggcgcaggc 1110 0 ggtatccagc acatcaatcg ctttgtccgg taactgacgc ccggagagat aacgttcgct 1116 0 cagcgttgct gcggcctgca aggcatcatc gtcaatcagc acgccgtgag accgttcata 1122 0 gaccgccgac agaccacgca gaataatggt ggcttcggca gcgttgggtt cgctgacctt 1128 0 cactaactgg aagcggcgcg acagggcggc gtctttctcg aagtattttt tgtactcgct 1134 0 ccaggtggtg gcggcgatgg ttttcagttc gccacgcgcc agcgccggtt tcagcaggtt 1140 0 ggagatatcc agcccgccct gctggttgcc cgcgccaatc agggtatgcg cttcgtcgat 1146 0 aaacagaatg accggcaccg gagaggaaat gacctccgcc atcagcccct tgaagcgttt 1152 0 ttcaaactca cccttcaccg atgccccggc ctgcaatgcg cccaggtcaa gggtcatgat 1158 0 atcggtgttt ttcagtttgt ccggcacctg gcctgccacg atgcgcagcg ccagcccttc 1164 0 aatcagcgcg cttttaccca cgcctgcttc gcccaccacc accgggttgt ttttacggcg 1170 0 gcggcagaga atgtcgatca tcaggtcgat ttcgtggtcg cggcacagta ctggggctag 1176 0 cctgccgtta cgggcgtctt ctgtcatgtt tttggcgtag cgggcaagca gggtgtcaga 1182 0 ggcgtccgtc agtgtgcctg cgcctttacc gtctgcatcc ggcacgactg attccgccga 1188 0 ctcctgtgtc cactgcacaa agtcctgttg cagacggtca cggttaatgc cggtcaacag 1194 0 ccgggcggca gcaggcggta tataacgcag cggcgaatgc agcaaggcca gcagcaacac 1200 0 gccgccgcgc agttcgctgt gctgcatctc agccgacgcc agcagccagc cctctttaag 1206 0 ccactcaacc agcatcgggg aaaacgccgg gtagctgtcc gcagaacggg cggttgtgta 1212 0 gttctctacc gtcaacgcct ggcgcaactc ttccatgcca atatcgccct ggcgggtaat 1218 0 aacccgcagg tcactgcgtg gcatggcgag catctgaata agcacatggc tgacggtaat 1224 0 ttccgctgcc tgctggctca tacattctga ggcggccatc tccagcgcct ggcgggagaa 1230 0 caggttcagc cgttttacca gcgtgggaag atcaatctgg atcataaacg tccttatcga 1236 0 agtaatttgt ttagctggtg caggatgtcc tgcgtctggc tgtccagccg caacagatag 1242 0 aacaggtaaa acaacgccag cacgacaacg ccaccacaaa aaatatgttt aacagtcagg 1248 0 cgactgatga gctgataacg cccgccttgg gtttttttgt cctggtgtaa cagcgggaaa 1254 0 ggggcatcgc cgcgcagttt atgcagaacg tggtacagac ggcggtagat ctgctcaaat 1260 0 tccccctgat cctgtactgc cactttgtag cgcccgcgaa atcccagaga aaaacagagc 1266 0 cagagaaatt ccagcagatc ctggtaacgt ttgggttcac ggatcaggcg ctccagcagg 1272 0 atgaaaactt tctcgccacc ccaggcttcg ttgtggaaat ggaccagcaa tgactgcttg 1278 0 atccactcgt tcttgttcga ccagccgtta ccgagcgccg cttcatcaat aaacgtgcag 1284 0 aggatgtagc gaaacgagat aatcacgccc ggttcgtagc cctgttcctg aagcagttgc 1290 0 tccacggcct gaacatctgt caccacctga gcaaaaagat gctccggcat cgtctggctg 1296 0 ttcatggtgg aaaggcgcat taccataccg agtagcggcg tcgccgcgtc gatcatcgga 1302 0 ttcaggctgt tgccatgaag cgcgagatgg tagtcgcgca ggcttttttc gtcgtatccg 1308 0 gtaaatggtg gcagagacag tgacccctca tccatcgtct taccctctta tcgcccacag 1314 0 ttgcatgttc agatccggga aactgccgga tacatgcagt gcaacggccc cggcggcagc 1320 0 catttctgtc caggcctggc cgctcttgtc gagttcgaaa tagctgaacc cggaatggta 1326 0 gggaagctgg cggggggcca ccatcagtgc gcgcagagga atacccggga tctgcacact 1332 0 gaccatattg cggatttttt ccggcgagga aattttcgac tgctggataa actgacgctg 1338 0 gatctgatcg acaggcatat ttgctgccac ggccagtaca aaggtggcag actgtagcag 1344 0 ttccgagtca tgaacatcgg cctgccagat gccgtcacgc agatgcagcg gcagattgac 1350 0 cgctcttggc gacagtacgg tatgcagcgc ccgtttgact tccggtaaca gtgttttaaa 1356 0 tgttttggtc aggtcatgat gatcatacac atcaagcggg cagggcaggc gtgacggctc 1362 0 tgtaaaggtc atcagttcac ccagcaactc ggcaagatca aggtagaaat cttccgggtg 1368 0 gagctgggat cggcgggcgc gatgggtaaa ccgggtctgg ttacggttaa gcaactgcaa 1374 0 catcataaat tccgccacat ccgcgatgcc gctctgcgcc ggagagccaa tacggtttgc 1380 0 cagatcgctt gcccgtccgc caatggcccc ctgtacctct ttgagataaa cacgcagttt 1386 0 cttactgacc tgaatattct ggcaggaggg gataaaatcg tcatccagcg tcagggagcc 1392 0 gtcggcatgg cgatcgctga tacggcaaag cgggagcgta atataggcac tcatatcttc 1398 0 tgcaccgctc ataatgcgcg gcgtcagttg tcccagcgtc agtgttcgcg cgtcgccttc 1404 0 ttctgaatgc agatcccgga catcggcata attcagccgg taacgcccga ttcgccgccc 1410 0 gtcgctgatt tcatttctca catcactggc gaccggcaga gcgaggtaaa tattgcggct 1416 0 tctttcgtcc ggaaaatttt gcgggtgcag cggatcgggc agtgcgtcct ggtcggggat 1422 0 agaaaagacg gtgccgtcag gcagtgtgcc tgacgcgctg tcaatcatga tcttaccctg 1428 0 cgccagcagt tcattgttga gggtgagttc ggtaaatccc caggataaat cattcatggc 1434 0 ccggaaacgc tggttatcca ggtagtcgtt gtaacgctgc tgttgctgga aatggtgtgg 1440 0 gcgcatcagc atcccttcct gccacatcac cttgttgcgg gtggttgcca taattattca 1446 0 tcctcttttt tcatttcgat gctgctttga cgtacatgca ccagcaggcg gtaatggtgg 1452 0 ccggttcctt ccaccgtctc gatttgtttc cattcagtgg cctggtcatc ggagaaatag 1458 0 gccacgacac caataaactg cgttttctca tccagcttta tcggcggcag ggttttgatg 1464 0 gtgtccggca acaggttgaa atcctggtgg tcgatatagt ttttacccag cacatccggt 1470 0 agcggcgtac tggctatctg gtcatagtcg gctgcctgca attttgagtc gtcagtcagg 1476 0 tacaccagtt gcacatccac ggcggctgat tcaccctccg cattggtatt ggtgtccggt 1482 0 tcagtcagca gggtgacggt tatttccgaa ggttgctcct tcaggctccc gacctggata 1488 0 tccgggtttt tgatcacctc gctgattttt ttcgccgttt cgcagccggt taatatgacg 1494 0 cacatcagca cgcaggccag aaacgccttc ctgttcatgc ttccggctcc cgctgttttt 1500 0 cacgaagcac ccggtcatag acctgggcgt agacctcgtt aaacagcatc tcaaacccct 1506 0 gctggcgatc ggaggccagt tcttcgtaat aatggctgta catttgccat gctccggcat 1512 0 catccagcgg ctggcgcagt tcatggctgc ggcggtactg cacaaagcgg cgcagcagat 1518 0 tttgtggtga gaaagcatcc agcaggacac gaagcgactc cacaatcgcc gcccggttag 1524 0 cttcttcgtg gtggcggaca ttgcgcaggc tttcactgac ggcggcggga gccgccagat 1530 0 gtaccgggct tttaccttcg gcaaacatca cgtcgagcgc ggtggcgtaa tccatgttca 1536 0 ggcgcagcgg gttatcttcc agcgggcgca aatgtttgtc tgagaggctg ttacgctgct 1542 0 gctgcaaatc gagcagacct tttattgcgg cctgtaacgt tcgtccggcc tcctccagaa 1548 0 aatcatccgc atcgtcggaa ttgctcacgg taagcgagcc gccaagaccg cgcagtaagg 1554 0 gggtgaccgc aaggtggcgt tgcgccattt ctgccgcaga gatgtcatca ttatgatcgc 1560 0 cagggctggc ataaatgggc ggcagatcca taaacggagt attgatcccc ccattacttg 1566 0 ccggatcgga cagcggtgcc gatggccgga cagccgcaat gcctgaaagc ggatcgcccg 1572 0 tggtaatcag gctttcggac tgaagtgcct ggagtggatc ggcagaaaaa ccatttacca 1578 0 cggtgtctgc aagctggtgc cggtgagtca ttcccggata gtgtggcgca ccctccgttg 1584 0 atagcagggt atccgtgagc atatcgcgat tggtaacgat ggtttcggga gtggccattt 1590 0 cctcatcgta atggggaata tctccccggt tcagatgaac cctcaccatc agccgtccga 1596 0 tctggatctc atcgccctgg cgcaactgta tcaggtctga tgttgctgtg acttttgcct 1602 0 gattcagcca cagttgtgcc gtctgcgggc gtagacaaaa tgtgccatcg tgcaggataa 1608 0 cggtaaaagc ctgggccgga atgctctgct gacgatcctg taccgaccag tggcattcgg 1614 0 gggcatggcc gacatttccc tgctgtgtga acagacagcg cgccgcccgc ccgctttcca 1620 0 gctcactgcc gttaatgacc tgcaatgaaa gcgtctgtag tttctcttcc ggcatattct 1626 0 gctccgtgat tatcataatt tacgaccgta ccctgatggt gactgagggt cgttcttccg 1632 0 gtgtgccgag gaagctggtc cagcccagca gcgcactttt gttatcgccc aggcgcattg 1638 0 cgcccacctg ctccggcgcc agccccagat gtaagtccca ggcaagctga tcgcgcagga 1644 0 tgaaggacac gaacgtcgtc agtggcagga agttttcgcc ggacggcaga aaagagagga 1650 0 actgttttcg ggtcaggctg gtaatactga gctggaattt tccgctgaga tcgggtactc 1656 0 gtgtacccag aacaaagttg cccagtaccg atcttcccgc cagtttttcg ccatttttaa 1662 0 gagaatagct ccccaggctg ttttgctgat ccggttcaat atccaccttg cgacgttgcc 1668 0 agttttgcag cgtcacttct gacaaatcaa agcagtggga caccaggcca cagataattt 1674 0 ccggggatcg tcccggattt gccaggatcc cggaatacgc cagcattttg ctgtgattaa 1680 0 tcgccagctt atcgcgaagc tggcggtggc ccagcccgac aagggagtac atgcgctgcg 1686 0 agaacgcatc cacaccgccg ttacgaaaac tgatgtgata gcggtactta cgccagatat 1692 0 gccagacaaa ctgggtcagg cggtggctga acatatccag aaaatcacct accggacttt 1698 0 gttcatgtac cgctttccag gccaggtgat cgaggtaata accggggaga ggcgactggc 1704 0 tcccctgtaa ccccataaag gtagtggtca tcctgaatgc ccctgacgta tcccgtttca 1710 0 gcgcactgat atcactgcac gggaaggcaa ggctggcatc ggcgctgaaa cgcagggttt 1716 0 cctgtgccgg atcgtcgcgc agggataatt ctggcgtccc cttttcaccc tttgccaggc 1722 0 ggtgcaacag ctccgccatc gcaaaaaaat tgtaagagca ggcattatgg aaaacctgtg 1728 0 ccagcggatc attctgctct ttatctgccg ggggatttcc cggactcaga taagaggatg 1734 0 ctgcccgatt ctttccgtcc atttccatgt ctcctggctt tctgtgttca caacggtcag 1740 0 catgtggaat gagttaacgc tggcgtacag cgacagaaaa tgcgaaagca ccgtaccgag 1746 0 cagatacatt tccccttcac agacaaacgg ctccgggtgc agatacagcg tggaggccag 1752 0 tccccggacg ggaatacccg taaacaggcg atcaacgggg cgggtctcca gacgctcaat 1758 0 ggcatccagc ttttgttgtg acagccgcgc cgtctgcgga tggtggattg cgtggcgatc 1764 0 aaagttggcg atgacctgct tcagcgcgtc cgtatccagt aatgacagat aattcaggtt 1770 0 catggcggag agcagggacc agtgcaggct gccatcaatg accggccaga gtggttgcgt 1776 0 cgggcgggta atgttgcgaa aggaagcaac agccgcattt ttaccggttg tgccggtgat 1782 0 atcgccggaa cgaatttgtg acggaagctc acggttggta caggtcagcg ataccgaaac 1788 0 cacttcatta ctgagcagag attcgtctga cggataactg ccatcagcat gtataaaggc 1794 0 aagggtatga tcaaagccgc gatggaacag ggatgttttg gtccggtgat gccagtacac 1800 0 cacctcccgc ttccggctgt attccatctg atggctgaaa ctttcaaagg ctggccactg 1806 0 gcgcgcggcc tgcgtcgaaa caggacgccc cagatctttt ttcctgaaca tatcctggac 1812 0 ctggctcacc acactgttaa cggaaaatac atcgtaatgt tgtgggtaat ggcggctggg 1818 0 aaccagcgga tagtctgccc gccggttgtc cagcgtgatg gcttctgcat ggtggataaa 1824 0 taaattaatg gcaggtgcgc aatacaggcg cagggaatcg cggcgcagcc ggatgtccac 1830 0 gggcaaaggg cgcgaaaaac gcagttgcag ggtaaagaat tccgcctgca atccgtcagg 1836 0 caaagccgga caaccacaaa gatcaaaaaa gagaaacgca tcggggtaac agaaatactc 1842 0 ctgaaggatc cggtagccgc tgtggacgtt tttcggccag ggcagcatgg catcctgcgg 1848 0 ctcaaaaccg acagctttta gcataaactc aggcaggcga atatgctgtt cacccacagt 1854 0 caggtcggca ccctgcaagt attcgcagaa ccataaataa agctggtcac gggtatagtt 1860 0 gtcgtcattg ccgagccaga agcgaagttt gttcagatcc agcgtgcgga agtccgttcc 1866 0 cggtgcgacc gaaaaggtga tgttgataac accattacgg gtcgtactgc ggttttcaat 1872 0 ctgctccagg cgaacgggca gcagccagat atcccggcag agggtgaagg tacagggagg 1878 0 cggctcctcc tttttagcat cagagggcag cacttcatca actctgattt ccccggcgtt 1884 0 ggttgtaaac tgctcattac gggggattaa caccggtaca gaagacttat ccatatccgg 1890 0 cgtatattca ataagggtca ttgccggaac cggacgcagg taattaggcc atagcatctt 1896 0 aataagcccg tgcgtcagtt ctgggaattc atcctcaatt ttctggcgga gattgccggt 1902 0 aagaaaagcc accccttcca gcaggcgttc aatatccgga tccgcatctt tttcggccag 1908 0 gaagcgggcc agatggggtt tttccgttgc cagcagcttg ctaagctggc gcaggtaatc 1914 0 gagttcttcc cgaaaatagc gttcttcaaa ttccatttgt cagtccaccc ggtaatgctg 1920 0 gctgccattc ggtgccatat caaattcaag cacctcatgc gtttcgttaa atgtcaccca 1926 0 ggctgtaata tgaaacgtca tatccagcgg gctggaggcg gatgaaacca ctgcctgcac 1932 0 ttcagcgtgt gagatccggg gttcatagcg ttctatacat tgctcgatgg cccgactcat 1938 0 ggattcgcgg aagttttcag ccccttccgg ttcatcaatg cccagctcag gcgcaccccg 1944 0 gcaactaccg gaccgggtat taagaatgtt tcttaggttc tggcgaatgg attgcctgag 1950 0 cgaatgaata ctgcctccct gccggtttct ggccgaagag gcttccatac gctcaaaaag 1956 0 agaacctgtg gttctttccc gatccagtat catggtgtgt tactccctgt ctaaccggcc 1962 0 aaccagggaa agctcaaaat ttgcccccat aaatttaaaa tgaggtctca cgcttagcgc 1968 0 aacctagtac cagccgggtt cgccttctac atccataacc tcaactttgg cagcgcgcag 1974 0 aggtttgcgg ctgcgcacgt ctgcaggcgg gttttcctgg tcggcaacat actgacggat 1980 0 ccaggtatta agctctcttt ctaagtcgct cctttctttc catgacccca gttgttcacg 1986 0 ctgcaacacc ttgatgtagt gcgctaaccg attgatgatg aagagataag gaagctgcgt 1992 0 acccagctta tagttggttt ctgcatcttt tcccggaaag tgcttcggtt tttgtaccga 1998 0 gtttgcagag aaaaaggctg cattatcaga gtctttacgc atggtaaggg tgataaaacc 2004 0 ctcttcagcc agttcaaatt cgcggcgatc ggtgaccagc acctcggttg ggattttggc 2010 0 ctgaatctgc cccatcgttt cgaacagatg caccggcaga tctttcactg cgccgccgct 2016 0 ttgcggaccg ataatgtttg gacaccagcg gtatttggca aaactgtctg cgatattgca 2022 0 tgccagcatc caggccgtat taccccacag ataatcttcg tggttctggc tgacatcttc 2028 0 gtaatagtta aagttcttaa cagggttatc tgttggtgaa tagggctggc gaagcaggaa 2034 0 gcggggtgcc gtaagcccta aatagcgcga atcttccgag tcacgcaggg cgcgccattt 2040 0 ggtgtaggcc ggaccttcaa agatggcata aagatctttg atattaggca gttcggtcca 2046 0 cgagttcagc cccataaact ccggggaaac ggaggacagg aacggtgcgt gcgccattgc 2052 0 gcccacggca ctgacgtatt gcagcagttt catgtcaggc gcggtatttt tgaactcata 2058 0 agcgcccagc acggcagcga tgggttcacc gccaaactgt ccgaaaccgg acgaataaac 2064 0 gtgcttataa aatccggact gaataatttc tggcgcaaac tcaaagtctt ccagaagttc 2070 0 ctgcttggtg acatgaagca cgttgacctt gatgttttca cggaaatcaa cgcgatccac 2076 0 catggttttc agtgagcgcc agaacgactc gacctgctga aaggcaggcg catggatgat 2082 0 gacatccatc tggcggctga tgcgttcatc aatatctgca atcatgctgt ccacggccag 2088 0 tttattgacc ggttcggcag atgcagtgga ttgcaggatg ctggcaataa aggctgtcac 2094 0 accctggcgg gcaacgtcat aaccttccga accgggctga atacgggtct gtgccatgat 2100 0 ttgatcaagc agcgacgatt cctgctcagg ctgcccggca tgactggaaa cgagttcctc 2106 0 ttcctgtaaa gacatactga aaatccttct gttttagctg tgtttctgaa accggctttt 2112 0 cgccgtcagt gaagtacgcg ctgccagtgc gacgcgctct gctgaaactc acaaaaatgg 2118 0 ataatctcat ccaatagatc actgatacgg cgatccagtg ttgtaatcag cgcagccaca 2124 0 ccatcctggt tgatttcaac ggacgggctg aaacatacct ggtaaaccac ctgcagaatg 2130 0 tctgcaacag agaggtggta tgtcccggag atatttttgt gtgccgtcat gcctggataa 2136 0 ccctgtttaa tgaaatagtg gtggttattt attgctcacc tggccgattt ctttgagcaa 2142 0 ctgctcgcgg gactcttcat tttccagcaa tgcctggagc tgggtacgga atgccggaag 2148 0 gttacccatc ggccccttca gtgcagtcag tgcttcacgc agttccagca atttattcac 2154 0 ttccggaacc tgccgggcca cgctatctgg tgaaaaatca tccagtgact tgatattcag 2160 0 cgccacattc atttcatcgt ccgttgtgct tcccttcagc gtggcgggga cggtaaaatt 2166 0 gaggccaatg gctgcttcag ccatcactgc accgaaattg tgcttgttaa cggaaactgc 2172 0 ctgacgttca tccagtgagg atgtttcctg cgtatttccg gtatcgccga caacgagcat 2178 0 gttaagcgga agttccactt cagccgtctg gccatctgtt tttgggacat acgatatatt 2184 0 aatacgttcg cgaggcgcga cgctgccttc aaattttttg ctcataaaag tgatccgtca 2190 0 tgttatctcg tacaggccat gaacacggca tattcgtacc gcaaaaaata tcggaaatgc 2196 0 cgtcttgatg gcggtgaaaa taaaatcacc actccttcat caccccgcat tttacgcttc 2202 0 aaaataaata agaaaaggac tttttatcga tcgtaaagag gggtattctg caagcgttaa 2208 0 atagatttta tgaacctgtg caattcgcgt caggtgtatt gtggcaataa tttaaatata 2214 0 gagttttttg tgtatcttat tgaattatat aataatttta ttaaacataa gctaatctaa 2220 0 tgattgcttg tttatatatt tgttttgtga ttgattaagt gggtattttt aaggaatatc 2226 0 tcaaaaatta tcaaaatgat aattcagaaa ggataaatac aatatttatt catgattcag 2232 0 ctttggccat tttatggagg caatacggac tttgaacagt tgggtatggc tatccagata 2238 0 tatattatta agttattgct gaataagaga tttaatgatt ttaaaaatag tttttacgac 2244 0 aaccgtaaat tctagctcgg tttgtatgta aaaaatactg aaaaatgatg cggttccgtg 2250 0 aagtgagctg catctgcctg tctgggatta acggcaggtc attgtaagta gtaattaacc 2256 0 acgttaacaa ggagtttaca aatgccaaca ccgtgttata tctccatcac tggtcagacc 2262 0 cagggaaata ttactgcagg tgcatttacc gctgattctg tcggcaacat ctatgtgcag 2268 0 gggcacgaag acgagatgct ggtgcaggaa ttcctgcata acgttactgt cccgaccgat 2274 0 cctcagtccg gtcagcctgc gggtcagcgt gctcacaagc ctttcatttt taccgtggcg 2280 0 ctgaacaaag cggttccgct gatgtacaac gcactggcct ccggcgaaat gctgccaacc 2286 0 actgaacttc actggtggcg tacctctgtg gaaggcaaac aggagcatta tttcactacc 2292 0 cgcctgactg attcgacgat tgtcgatatg aaactgcata tgccgcattg ccaggacccg 2298 0 gcgaaacgcg agttcaccca gttgctcgaa gtttcactgg cctaccgcaa aattgaatgg 2304 0 gaacacgtca aatctggcac ctccggtgcc gacgactggc gcgcaccgct ggaagcataa 2310 0 gttaagccaa cagcatccgg ctatcaggcc ggatgctgtt tttgtattac gccgtagaaa 2316 0 gaaaggttgt cagtaagggg ttacgttcac gggagatggc ggctgccgga aacttcggcg 2322 0 gtagcgtgcc tgaacgcaag cgtagcactg tactgtcaca gccgctttaa cagcgaactg 2328 0 tctgtttttc cttaaccccg gaggttgcta tgtcaaccgg attacgtttc acgctggaag 2334 0 tggacggcct gccaccggat gcttttgcgg tggtcttctt tcatctgaac cagtcactct 2340 0 cttcgctttt ttccctcgct ctctctctgg tcagccagca gtttctctcc cttgaattcc 2346 0 agcagatcct cgacaaaatg gcctacctga cgatatggca gggcgatgac gtacagcgcc 2352 0 gggtgaaagg tgtggtgacc tggtttgaac tgggggagaa cgacaaaaac cagaagctgt 2358 0 acagcatgaa ggtgtgcccg ccgctgtggc gcacagggct gcgccagaac ttccgtatct 2364 0 tccagaatga ggacatcgca agcatcctcg gcacgatatt gcaggaaaac ggggtgaccg 2370 0 agtggagccc gctgttcagc gagccacatc cttcccgtga gttttgtgtc cagtacggtg 2376 0 agactgatta cgatttcctg tgccggatgg cggcggagga aggcatcttc ttttatgagg 2382 0 agcacgcgca aaaaagtacc gaccagagcc tggtcctgtg cgataccgtg ctttatctgc 2388 0 cggagtcctt tgagatcccc tggaatccga acacccgtac cgaggtaagc accctctgca 2394 0 tcagccagtt tcgctacagc gcacaaatcc gcccttcttc cgtggtgacc aaagactaca 2400 0 cctttaaacg ccccggctgg gccggacgtt ttgaccagga aggccagcac caggattacc 2406 0 agcgcacaca gtatgaagtg tatgactatc ccggacgttt caagggcgcc cacgggcaga 2412 0 actttgcccg ctggcagatg gacggctggc gaaacaacgc agaagtggcg cgcggaacaa 2418 0 gccgttcgcc ggagatatgg ccgggacggc gaattgtgct gacggggcat ccgcaggcga 2424 0 acctgaaccg ggaatggcag gtggtggcaa gtgaactgca cggtgagcag ccgcaggcgg 2430 0 tgccgggacg caggggttca ggcaccacgc tggataacca ttttgcggta ataccggcag 2436 0 acagaacatg gcgaccacag ccgttgctga aaccgctggt ggacggcccg cagagcgccg 2442 0 tcgtgacggg accggcaggc gaggaaatct tctgtgatga acatggccgc gtgcgggtga 2448 0 aatttaactg ggaccgctat aacccgtcaa accaggacag ttcatgctgg atccgtgtgg 2454 0 cacaggcgtg ggcaggcacc gggtttggta acctggcgat accgcgtgtg ggtcaggagg 2460 0 tcattgtgga cttcctcaac ggcgatccgg accagccgat cattatgggg cgtacctacc 2466 0 accaggaaaa ccgcacaccc ggtagcctgc cggggacgaa gacgcagatg accattcgtt 2472 0 cgaaaaccta taagggcagc gggtttaatg aactgaagtt tgacgatgcg acagggaaag 2478 0 aacaggtcta catccacgcg cagaagaaca tgaacaccga ggtgctgaat aaccgcacca 2484 0 cggatgtgat aaacaaccat gccgaaaaaa taggtaacaa ccaggcgatc accgttacca 2490 0 ataaccagat cctgaacatt ggcgttaatc agatacagac ggttggtgtc aaccaggtgg 2496 0 aaacggtagg cagtaaccag attatcaaag tgggatcaaa ccaggttgaa aaggtgggga 2502 0 tcattcgtgc gctgacggtg ggtgtggcgt atcagacgac ggtaggcggc attatgaata 2508 0 cctcggtggc gttgttgcag tcctcacagg tagggctgca taaatcactg atggtgggaa 2514 0 tgggctacag cgtcaatgta gggaataacg tcaccttctc ggtgggcaag acgatgaagg 2520 0 aaaacaccgg acaaacagca gtttattctg ccggtgagca tcttgaactc tgctgtggta 2526 0 aggcaaggct ggtgctgacg aaggacggaa gcatatttct taatggtacg cacattcatc 2532 0 tggaagggga gtcggatgtg aacggtgatg cgccggtgat taactggaac tgtggtgcca 2538 0 cacaacctgt accggatgcg cctgtgccga aagatttacc ccccggaatg ccggatatgc 2544 0 ggcaattttg agtcaggtgc aaaaaatcaa aacggaactg gtgcagtgac cagataaacc 2550 0 atattaaaag cagaaggaat tgattcatgg gaggaaaacc ggcggcgcgg cagggtgaca 2556 0 tgacccgcaa gggactggat attgtgcagg gttcagcagg ggtgctgata ggtgcgccga 2562 0 cgggcgtggc ctgctcggtg tgtccgggag ggattaccta tgctaacccg gtgaacccgg 2568 0 tgctgggtgc gaaggtgctg ccgggcgaga cggaccttgc gctgcccggc ccgctgccgt 2574 0 ttattctttc ccgcgcctac agcagctacc ggaccagaac acccgcgccg gtgggggtgt 2580 0 ttggtcccgg ctggaaagcg cccttcgata tccgcttaca gatacgcgat gaaggcctga 2586 0 tactcaacga caacggcggc aggagcattc actttgagcc gctgtttccc ggcgagataa 2592 0 gctacagccg cagcgagtcg ttctggctgg cgcggggcgg ggtggcggag cagcacagtt 2598 0 cgcagccgct aagcgcgctc tggcaggtgc tgccggaaga tgttcgcctg agtccgcata 2604 0 tgtacctggc gacaaacagc cttcaggggc cgtggtggat actcaactgg ccggagcggg 2610 0 tgccgggggc ggacgaggtg ctgccgccgg agccgcccgc ataccgggtg ctgacgggcg 2616 0 tggtggatgg cttcgggcgg acgctggcct ttcaccgggc ggcggagggt gatgtggcgg 2622 0 gcgcggtgac gggggtgacg gacggcgcgg gccgccgttt tcacctggtg ctgaccacac 2628 0 aggcacagcg ggcggaagta ttccgtaaac agcgcgccac gtctttatct tcccctgccg 2634 0 gtccccgttc tgcttcctct tctctggttt tccccgacac gctgcccgcc ggtacagaat 2640 0 acggtgccga taacggtatc cggctggagg cggtatggct gacacacgac ccggcatacc 2646 0 cggatgaact gcccgccgcg ccgctggcgc gctacacgta cacggccagc ggagaactgc 2652 0 gggcggtgta tgaccgcagc gggacgcagg tgcgcgggtt tgcttatgat gcggagcacg 2658 0 ccgggcggat ggtggcgcac cattatgcgg gtaggccgga gagccgctac cggtatgatg 2664 0 ataccggccg ggtgacggag ctggtcaacc cggaggggct ggactaccgc tttgagtacg 2670 0 ggcaggaccg tgtgaccatc acggacagcc tgaaccggcg ggaggtgctg tacacggaag 2676 0 gcgagggtgg cctgaaacgt gttgtgaaga aggaacatgc ggacgggagc atcacccgca 2682 0 gcgagtatga tgaggcgggg aggctgaagg cacagacgga tgcggcggga cggcggacgg 2688 0 agtacagcct gcatatggcg tcgggtgcgg tgacagcggt gacggggccg gacggcagga 2694 0 cggtgcggta tggctataac agccagcggc aggtgacgtc agtgacgtac ccggacgggc 2700 0 tgcgcagcag ccgggagtat gatgagaagg gaaggctggc ggcggagacc tcgcgcagcg 2706 0 gagagacgac gcggtacagc tatgatgacc cggcgagtga gctgccgaca gggatacagg 2712 0 acgcgacggg cagtacaaaa cagatggcat ggagccgtta cggtcagctg ctgaccttta 2718 0 cggactgctc ggggtacacg acgcggtatg agtatgaccg gtacggtcaa caaatcgccg 2724 0 ttcaccggga agaaggcatc agcacttaca gcagttataa cccgcgtggc caactggtca 2730 0 gtcagaagga tgcgcagggg cgtgaaaccc gttatgagta cagcgccgca ggcgacctca 2736 0 ccgctatcgt tgccccggac ggcagccgca gtgagataca gtatgatgcg tggggaaagg 2742 0 ccgtcagcac cacgcagggc ggtctgacgc gcagcatggg gtatgacgct gccgggcgca 2748 0 tcaccgtgct gaccaacgag aacggcagcc agtccacgtt ccggtatgac ccggtggaca 2754 0 ggctgactga acagcgcggt tttgatggcc ggacgcaacg ttaccactat gacctgaccg 2760 0 gaaaactcac gcagagtgaa gacgaggggc ttgtcaccct ctggcactac gatgcgtcgg 2766 0 accgcatcac gcaccggacg gtgaacggcg acccggcaga gcagtggcag tatgatgagc 2772 0 acgggtggct aaccaccctc agccatacca gtgaaggcca ccgggtgtcg gtccactacg 2778 0 gctatgacga taaaggccgc ctgacgggtg aacggcagac ggtggagaac ccggagacgg 2784 0 gggagatgct gtgggagcat gagacggggc acgcgtacag cgaacagggg ctggcgaccc 2790 0 gtcaggagcc ggacggtctg ccgccggtag agtggctgac gtatggcagc ggttatcttg 2796 0 cggggatgaa gctgggcgga acgccactgg tcgagtacat gcgggaccgg ctgcaccgtg 2802 0 agacggcccg cagcttcggc ggggaggcat atgaacttgc caccgcctgg aataccagcg 2808 0 gccagctccg gagcaggcac ctgaaccttc cgcagcttga ccgtgactac gactggaacg 2814 0 acaacggaca gctaatccgc atcagcggcc cgcaggagag ccgggagtac cgttacagtg 2820 0 acacgggaag gctgacgggc gtccacacca cggcagcgaa cctggatatc gatatcccgt 2826 0 atgcaacgga cccggcagga aaccggctgc cggacccgga actgcacccg gacagcaccc 2832 0 tcacggcatg gccggataac cgcatcgcgg aagatgcgca ctatgtctac cgctacgatg 2838 0 aatacggcag gctggcggag aagacggacc gcatcccgga aggggttatc cggatgcacg 2844 0 acgagcgcac ccaccactat cactacgaca gccagcaccg cctggtgttc cacacgcgga 2850 0 tacagcacgg cgaaccacag gtggagagcc ggtacctcta tgacccgctg ggccgccgga 2856 0 cgggaaaacg ggtgtggcgg cgggagcgtg acctgacggg gtggatgtcg ctgtcgcgta 2862 0 aaccggagga gacctggtac gggtgggacg gtgacaggct gaccactgta cagacccaac 2868 0 agacaagaat ccagacggta taccagccgg gaagcttcac gccgctcctg agaatcgaaa 2874 0 cagagaatgg tgaacaggcg aaggcgcggc accgtagcct ggcggaggtg ttgcaggagg 2880 0 acacgggtgt gacgctaccg gcggagctgg cggtgatgct gggaaggctg gagcgggagc 2886 0 tgcggcaggg cagcgtgagt gaagaaagcc agcagtggct tgcgcagtgc gggctgacgg 2892 0 cggagcagat gggcgcgcag ctggaggcgg gatacatccc ggagaggaaa cttcatcttt 2898 0 accactgcga ccaacgggga ctgccgctgg ggctcatcag cccgggaagg gagacggcgt 2904 0 tgactgcgga gtatgacgag tggggaaacc tgctgagcga aaccagcgcg cagccccttc 2910 0 aacagtcact ccgtttcccg ggccagcagt atgatgagga gtcggggctg tactacaacc 2916 0 gcaaccggta ctatgatccg ttgcagggga gatatatcac ccaggacccg atagggctgg 2922 0 aggggggatg gaacctgtat cagtacccac tcaatcctat tgaacatata gatccgttgg 2928 0 ggttagcact tgatttgaat tattattctc cgtcagatcc tatatataaa ggttctctta 2934 0 atgtaaggga atttccaacg ggttttacag ttggaggtca tggttcgcct acatctatga 2940 0 gtgatgacag aatcaaaaaa ggaagtgatc tgacaataaa acaattagct agcgacataa 2946 0 gagcgaatcc taaatatcat gaaggtatgc ctgtagtctt gttttcctgc gaaacaggaa 2952 0 aaggcaaaaa ttcatttgca cagaaactag ctaacgaact tgatgctaca gtgattgctc 2958 0 ctgatgaaat aatatggatt tggccggatg gaaactatgc tattatgggg caaacagcta 2964 0 ggataacaat aggcggtaag gacaacgggg tgtttgaatt ggtgccagac gagaaacaac 2970 0 caggggactt tcataagttt acacctacag gaagcaaata gtaatgaaag tatttacttt 2976 0 tttgttgatt atcatggtat gtctttataa ctttggagtg agggctgcta tggataactc 2982 0 aaaacattct gatgaggcgg aaaaattatt ggcggagctt tctgctagaa aaggtgaagg 2988 0 tgaaggtgaa ggtgaaggtg aaggtgaagg tgaaggtgaa ggtgaaccaa aatcaacagt 2994 0 aagcgtcttt tatttgcagc cagaagaagt aaatacttta tcacaccagg caaaacgagg 3000 0 cgatggcgag gcgggtttta ggttgttctt gtactacaag ttgtccaatt atgatgaaga 3006 0 aaaaagtagt cagtggttaa aaatagcggc taataatggt catgcgacag ctcagtatcg 3012 0 gttatatgta gagttacaag aacaaggtga aaccaaggaa gctaatgaat ggttacaaaa 3018 0 aattaaattg gctgccagta ataatgacag ttcagcaata tggttcttgg tgaattgtta 3024 0 taaaaaccag ggaaataaaa aagaagcatt gcaatgggca tataaactca aagcgagtaa 3030 0 acagccgctt gatgcagatc gactaattga agaattaacg aaagaacaaa agtagcttta 3036 0 aacaggtaac agaaaaatgg agagtagaaa aactttacca gtcgctacaa cacctacaca 3042 0 caaaattacg tttacgacga ctgcaacaag ctcatcaaag cgcaagttga aaccaaaact 3048 0 ggcatcttcg tcgccggtta tcattacgat gtacttggca gatgcatcaa aagtcgcaag 3054 0 agaaaagatg aaaatatagc tttttgtatc attaagtatg tggccagcac atgactcggc 3060 0 atagatctta tgactaagat tctacacccc aaacctaagt atgggccaaa gaagccgttt 3066 0 ggttcatttt ttatatctcc agcattttag tggatggagc ttatgaaaat aataaggtta 3072 0 ttattgctgg cttgttcgat aaccattcat ttttttattg taaaagaaca tgtatttaaa 3078 0 atattcaatc aacatgctta ttgttttttg tttgcttttt atgttttgat agtgttctgt 3084 0 tttttgttat tttttaaaag atcttttatt gttgatttaa tagcttgtat aataattcct 3090 0 tatatttctt ctgtcataag tttcttgttt ttgtccatgt taatatctcc tcacctcagg 3096 0 gaaagatcac ctaacgccgc ttttttgtac taaataattc gcactaaatg ttcaataatt 3102 0 gagatgttcc ttattatcta aaactgtttt tcacagctta catatgatca aatactcctt 3108 0 gcataaataa ggagaacaaa atggaactta aaaaattgat ggaacatatt tctattatcc 3114 0 ccgattacag acaagcctgg aaagtagaac ataaattgtc agatattcta ctgttgacta 3120 0 tttgtgccgt catttctggt gcagaaggtt gggaagatat agaggatttt ggtgaaacgc 3126 0 atctcgattt tttgaggcaa tatggtgatt ttgaaaatgc tattcctgtc cacgatacca 3132 0 ttgccagagt tgtatcctgt atcagtcctg caaaatttca tgagtgcttt attaactgga 3138 0 tgcgtgactg ccattcttca gatgataaag acgtcattgc aattgatgga aaaacgctcc 3144 0 ggcactctta tgacaagagt cgccgcaggg gagcgattca tgtcattagt gcgttctcaa 3150 0 caatgcacag tctggtcatc ggacagatca agacggatga gaaatctaat gagattacag 3156 0 ctccccctga acttcttaac atactggata ttaaaggaaa aatcatcaca actgatgcga 3162 0 tggggtgcca gaaagatatt gcagagaaga tacaaaaaca gggaggtgat tatttattcg 3168 0 cggtaaaagg aaaccagggg cggctaaata aagcctttga ggaaaaattt ccgctgaaag 3174 0 aattaaataa tccagagcat gacagttacg caattagtga aaagagtcac ggcagagaag 3180 0 aaatccgtct tcatattgtt tgcgaagtcc ctgatgaact tattgatttc acgtttgaat 3186 0 ggaaagggct gaagaaatta tgcgtggcag tctcctttcg gtccataata gcagaacaaa 3192 0 agaaagagcc aaaaatgacg gtcagatatt atatcagttc tgctgattta accgcaggga 3198 0 agttcgccac agcaatccga aaccactggc acgtggagaa taagctgcac tggcgtctgg 3204 0 acgtggtaat gaatgaagac gactgcaaaa taagaagagg aaatgcagca gaattatttt 3210 0 cagggatacg gcacattgct attaatattt tgacgaatga taaggtattc aaggcagggt 3216 0 taagacgtaa gatgcgaaaa gcagccatgg acagaaacta tctggcgtca gtccttgcgg 3222 0 ggagcgggct ttcgtaatct tgccctggct gcaccgtgag acggcccgca gcttcggcgg 3228 0 ggcgggcagt acagcggggt acgaacaggt cacggcgtac accctcacag ggcagctaca 3234 0 gagcaggcac ctgaacctcc cgcagcttga ctgtgactac gactggaacg acaacggaca 3240 0 gctaatccgc atcagcggcc cgcaggagag ccgggagtac cgttacagcg acacgggaag 3246 0 gctgacgggc gtccacacca cggcagcgaa cctggatatc gatatcccgt atgcaacgga 3252 0 cccggcagga aaccggctgc cggacccgga actgcatccg gacagcacgc tcacggcgtg 3258 0 gccggataac cgcatcgcgg aagatgcgca ctatgtctac cgctacgatg aatacggcag 3264 0 gctgacggag aagacggacc gcattccgga aggggttatc cggatgcacg acgagcggac 3270 0 ccaccactac cattacgaca accagcaccg cctggtgttc tacacgcgga tacaatacgg 3276 0 cgagccgctg gtcgagagcc gctacctcta tgacccgctg ggccgccgga cggggaaacg 3282 0 ggtgtggcgg cgggagcgtg acctgacggg gtggatgtcg ctgtcgcgta aaccggaggt 3288 0 gacctggtac gggtgggacg gcgacaggct gacgacggta cagaccggca ccacacgtat 3294 0 ccagacggta taccggccgg ggagcttcac accgctcatc cgcatcgaaa cggagaacgg 3300 0 cgagcgggag aaagcgcagc gccgcagcct ggcggagaaa ctccagcagg aagggagtga 3306 0 ggacggtcac ggtgtggtgt tcccggcaga actggtgagg atgctggaca ggctggagga 3312 0 agaaatccgg gcagaccgcg tgagcagtga aagccgggcg tggcttgcgc agtgcggact 3318 0 gacggtggag caactggaaa aacaggtgga gccggaatac acgccggcgc gcacgctgca 3324 0 tctgtaccac tgtgaccacc ggggactgcc gctggcgctt atcagcgaag acggcaatac 3330 0 ggcgtggagc gcggaatatg atgaatgggg caaccagctt aatgaggaga acccgcatca 3336 0 cctgcaccag ccgtaccgtc tgccgggcca gcagcatgat gaggagtcgg ggctgtacta 3342 0 taatcgtcac cggtactacg atccgttgca ggggcggtat atcaccccgg acccgattgg 3348 0 gttgagaggt ggatggaata tgtatcagta tccgttgaat cccatacaag tgatagaccc 3354 0 aatggggtta gatgcgattg agaatatgac atcaggtgga ctaatttatg ccgtatctgg 3360 0 tgtacctgga ttgattgttg caaacagcat tactaacagt gcttaccagt tcggttatga 3366 0 tatggatgct attgttggcg gagctcataa tggggccgcc gatgcaatga gatattgtta 3372 0 cttgatgtgt cgaatgacta agacatttgg atcaacaata gctgacgtga taggtaaaaa 3378 0 tcatgaggcg gctggggata gacaaggtca gccagctaaa gaaagaatca tggatcttaa 3384 0 aaataacact gtcggtattg cttgtggcga tttttctgcc aaatgtagcg atgcatgtat 3390 0 tgaaaaatat aacattgggc aactcttcgg gttagatggt ataaaagcag ataatccaat 3396 0 aaaagcaaag caagggagtt cagatgcttc aaattattag aggcaaactt gtcatttttt 3402 0 taattaccct ttgtttattt gttgtttacc ttgggtttga taacaattca aattctgaca 3408 0 tcgtatttta tggacataaa acaccaaaga gcgttgagat atatctttct gaaaaaatat 3414 0 tatttataaa ataattaatg accaaaaaat tagtagaggg aatggtcatt ttataagtat 3420 0 aatggttaat aattacaaga cgcactgtgg agtggttgat ataaatctta attttttcaa 3426 0 tgatattctt tatagcgtgc gattaaaaaa cattagtaaa ctggagaata tggagttctg 3432 0 cgctacaaaa caacgggtgt attttagtga taaaaacaag aaggctagtt ataaaataat 3438 0 taattatgga gactattatg atgttgatta ttatgataac aatttgaaaa atgaagtttt 3444 0 tgactggatt ggtaaatggt cataatgaac aacaccagaa agagaaaaat ataaaataca 3450 0 tacagaaaga catgagagca agggacgggg cagggcaaga tcatgaaaat cgtgatgtaa 3456 0 atcacgattt tcatcctggc tttaacgcct acaggtgatc aaaatttaac ctttggaata 3462 0 actaaaaaga taaaaaggac gccaggtgag tattcaaagt ttgcttgatt atatttcagt 3468 0 gatccctgat atacgacaac aaggaaaggt taaacataaa ttatctgata ttttgtttct 3474 0 caccgtatgt gcagtaattg caggtgccga tgagtggcag gaaattgaag attttggaca 3480 0 tgaaagactt gaatggctaa agaaatatgg tgattttgat aatggcattc cggtcgatga 3486 0 caccattgca cgcgttgtga gtaacattga cagtttggcc tttgaaaaga tatttattga 3492 0 atggatgcag gagtgccatg aaatcactga tggtgaaatt atagcaatag atggaaagac 3498 0 cataagaggc tcctttgata agggaaaaag aaaaggagca atccatatgg tgagtgcatt 3504 0 ctcgaacgaa aatggtgttg tactggggca ggtaaaaacg gaagccaaaa gtaatgagat 3510 0 tacagccatt ccagagttgc ttaacctact ggatttaaag aaaaatttga taaccattga 3516 0 tgctatgggc tgtcagaaag atatcgcttc gaagatcaaa gataaaaaag cagattatct 3522 0 tctggcagta aaaggcaatc aggggaaatt acatcatgca ttcgaggaaa aatttcctgt 3528 0 aaatgtgttt tctaattata aaggcgattc gtttagtacg caggagataa gtcatggaag 3534 0 aaaagaaaca cgtttgcata ttgtcagtaa cgtaacgcct gaattttgtg attttgaatt 3540 0 cgaatggaag ggattaaaaa agctttgtgt agcattgtca ttcaggcaga agaaagaaga 3546 0 taaatcagca gaaggtgtaa gcatccgata ttatatttca tcaaaggata tggatgctaa 3552 0 agaatttgca catgctatca gagcgcactg gctgatcgag cacagtcttc attgggtgtt 3558 0 agatgtaaaa atgaatgaag atgccagccg gataagaaga ggaaacgcag ccgaaataat 3564 0 atctggaata aagaagatgg cactgaattt attaagagat tgcaaagaca ttaagggtgg 3570 0 ggtgaagagg aaaagaaaga aggttgcgtt aaacacatgt tatatagaag aagtgcttgc 3576 0 atcctgctca gagcttgggt ttcgaactga caaaatgaaa aatttaacac agatttaatt 3582 0 catgctcttg ccctgcgggg ggattattaa atcttcccag ttttttatta tttaactctc 3588 0 gctcagcaca ctaaacatcc ctttctgaat 3591 0 <210> 979 <211> 99 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(320..616) <400> 979 Met Ile Ile Ile Asn Leu Arg Leu Thr Leu Leu Phe Ile Leu Ala Thr 1 5 10 15 Phe Thr Tyr Ser Val Gln Ser Asp Glu Phe Asp Asp Gln Thr Thr Tyr 20 25 30 Thr Gln Tyr Arg Tyr Phe Ser Thr Ala Ile Pro Glu Asp Ile Arg Arg 35 40 45 Phe Met Phe Tyr Val Asp Tyr Cys Phe Val Asp Leu Ala Phe Asp Ile 50 55 60 Glu Thr Asp Ser Met Thr Ala Lys Asn Asp Ile Ile Asn Glu Cys Thr 65 70 75 80 Pro Leu Lys Glu Arg Asn Lys Thr Leu Lys Glu Lys Tyr Lys Lys Met 85 90 95 Lys Arg * <210> 980 <211> 150 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(613..1062) <400> 980 Met Arg Lys Ile Thr Ile Ile Leu Leu Leu Thr Phe Ser Cys Thr Lys 1 5 10 15 Gly Leu Ala Phe Asp Ile Ser Met Ser Lys Glu Cys Ser Gly Val Asp 20 25 30 Glu Leu Glu Phe Ile Asp Cys Val Lys Asn Ser Phe Ile Met Ser Thr 35 40 45 Ile Thr Leu Lys Lys Ala Glu Ala Asn Ile Lys Glu Lys Ile Gln Lys 50 55 60 Trp Asn Ser Asp Glu Asp Glu Ala Ile Arg Lys Glu Ala Val Ile Ser 65 70 75 80 Leu Lys Arg Leu Glu Ser Ser Asn Arg Glu Phe Ile Arg Tyr Arg Phe 85 90 95 Ala Gln Cys Ser Phe Thr Leu Thr Trp Gly Ala Arg Val Gly Arg Leu 100 105 110 Ala Phe Ser Arg Leu Tyr Pro Cys Tyr Thr Glu Leu Asn Lys Ile Arg 115 120 125 Ala Met Gln Leu Asn Asn Ala Tyr Ile Ser Asp Phe Gln Asn Pro Asp 130 135 140 Glu Ile Ser Ser Lys * 145 <210> 981 <211> 216 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1065..1712) <400> 981 Leu Ser Ser Thr Pro Tyr Phe Gln Pro Leu Asp Trp Tyr Ile Ile Lys 1 5 10 15 Ala Met Leu Trp Thr Glu Asn Asp Ala Glu Asn Thr Ser Gln Trp Asn 20 25 30 Gly Tyr Pro Leu Gln Ile Gly Arg Phe Arg Lys Asp Lys Ala Met Pro 35 40 45 Ala Leu Ile Ser Gly Glu Lys Ser Thr Ala Leu Val Thr Pro Pro Gln 50 55 60 Trp Arg Asn Lys Ala Phe Asn Gly Leu Lys Asp Pro Glu Arg Asn Tyr 65 70 75 80 Trp Ala Lys Glu Gln Ile Thr Gly Ser Pro Glu Glu Asn Ile Lys Ala 85 90 95 Ala Ile Thr Tyr Leu Met Met Lys Leu Ser Asn Thr Lys Glu Glu Ser 100 105 110 Thr Ile Asp Gln Tyr Asp Ser Thr Leu Tyr Ser Ala Ile Val Gln Lys 115 120 125 Gly Asp Leu Ala Asp Asn Ile Arg Lys Glu Arg Lys Thr Thr Ile Pro 130 135 140 Asn Leu Thr Lys Asn Asn Pro Gly Lys Asn Leu Asp Lys Ile His Pro 145 150 155 160 Gly Asp Ile Leu Tyr Tyr Gln Lys Ala Ser Met Lys Val Ile Ile Thr 165 170 175 Gly Trp Lys Pro Ile Thr Ile Lys Asn Val Ala Met Asn Tyr Asn Gly 180 185 190 Gly Gly Asp Pro Lys Tyr Ala Ile Lys Leu Gln Phe Val Tyr Thr Leu 195 200 205 Leu Thr Lys Asn Arg Val Leu * 210 215 <210> 982 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1740..1961) <400> 982 Met Ala Asn Asn Ile Leu His Ser Ser Thr Ser Asp Ser Glu Ser Lys 1 5 10 15 Asn Thr Ser Thr Asp Ser Thr Leu Phe Asn Glu Lys Phe Pro Phe Gln 20 25 30 Leu Arg Gln Asp Phe Ala Ser Arg Ile Thr Glu Asp Glu Ser Asp Phe 35 40 45 Phe Lys Trp Lys Lys Ile Arg Glu Leu Ala Phe Val Ser Asn His Lys 50 55 60 Glu Trp Asn Lys Tyr Asp Leu Leu Ile * 65 70 <210> 983 <211> 160 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1982..2461) <400> 983 Met Ala Asn Leu Ile Tyr Leu Thr Leu Asn Gly Asp Asn Gln Gly Leu 1 5 10 15 Ile Ser Ser Gly Cys Ser Ser Gln Pro Ser Ile Gly Asn Lys Ala Gln 20 25 30 Thr Ala His Ile Asp Gln Ile Met Ile Tyr Glu Phe Met His Gly Leu 35 40 45 Asn Arg Asp Gln Asn Val Asn His His His Leu Thr Ile Lys Lys Pro 50 55 60 Ile Asp Lys Ala Ser Pro Leu Leu Gly Lys Ala Ile Cys Asp Asn Glu 65 70 75 80 Leu Leu Thr Cys Asp Phe Ser Phe Tyr Arg Thr Asn Lys Phe Gly Ile 85 90 95 Asn Glu Leu Phe Tyr Lys Ile Lys Leu Thr Gly Ala Lys Ile Ser Asp 100 105 110 Ile His Val Ser Ile Ser His Ile Val Val Asp Asn Ser Val Gln Pro 115 120 125 Glu Glu Ser Val Ser Phe Ser Tyr Glu Ser Ile Ile Trp Glu His Cys 130 135 140 Ser Ala Gly Thr Ser Ala Tyr Ser Leu Trp Glu Asp Arg Leu Phe * 145 150 155 <210> 984 <211> 470 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2427..3836) <400> 984 Met Asn Ser Asn Val Leu Thr Gln Thr Ile Val Thr Gly Ser Asp Pro 1 5 10 15 Arg Gly Leu Pro Glu Phe Ser Ala Ile Arg Glu Glu Ile Asn Lys Ala 20 25 30 Ser His Pro Ser Gln Pro Glu Leu Asn Trp Lys Leu Val Glu Ser Leu 35 40 45 Ala Leu Ala Ile Phe Lys Ala Asn Gly Val Asp Leu His Thr Ala Thr 50 55 60 Tyr Tyr Thr Leu Ala Arg Thr Arg Thr Gln Gly Leu Ala Gly Phe Cys 65 70 75 80 Glu Gly Ala Glu Leu Leu Ala Ala Met Val Ser His Asp Trp Asp Lys 85 90 95 Phe Trp Pro Gln Gly Gly Pro Ala Arg Thr Glu Met Leu Asp Trp Phe 100 105 110 Asn Ser Arg Thr Gly Asn Ile Leu Arg Gln Gln Ile Ser Phe Ala Glu 115 120 125 Ser Asp Leu Pro Leu Ile Tyr Arg Thr Glu Arg Ala Leu Gln Leu Ile 130 135 140 Cys Asp Lys Leu Gln Gln Val Glu Leu Lys Arg Val Pro Arg Val Glu 145 150 155 160 Asn Leu Leu Tyr Phe Met Gln Asn Thr Arg Lys Arg Leu Glu Pro Gln 165 170 175 Leu Lys Ser Asn Thr Glu Asn Ala Ala Gln Thr Thr Val Arg Thr Leu 180 185 190 Ile Tyr Ala Pro Glu Thr Gln Ala Ser Ser Thr Pro Glu Ala Val Val 195 200 205 Pro Pro Leu Pro Gly Leu Pro Glu Met Lys Val Glu Val Arg Ser Leu 210 215 220 Thr Glu Asn Pro Pro Gln Ala Ser Val Ile Lys Gln Gly Ser Thr Val 225 230 235 240 Arg Gly Phe Ile Ala Gly Ile Ala Cys Ser Val Ala Val Ala Ser Ala 245 250 255 Leu Trp Trp Trp Gln Val Tyr Pro Val Gln Gln Gln Leu Leu Gln Val 260 265 270 Asn Asp Thr Ala Gln Gly Ala Ala Thr Val Trp Met Ala Ser Pro Glu 275 280 285 Leu Glu Asn Tyr Glu Arg Arg Leu Gln Gln Leu Leu Asp Thr Ser Pro 290 295 300 Val Gln Pro Leu Glu Thr Gly Met Gln Met Met Arg Val Ala Asp Ser 305 310 315 320 Arg Trp Pro Glu Ser Leu Gln Gln Gln Gln Ala Ser Thr Gln Trp Asn 325 330 335 Glu Ala Leu Lys Thr Arg Ala Gln Ser Ser Pro Gln Leu Arg Gly Trp 340 345 350 Leu Gln Thr Arg Gln Asp Leu His Ala Phe Ala Asp Leu Val Met Gln 355 360 365 Arg Glu Lys Glu Gly Leu Thr Leu Ser Tyr Ile Lys Asn Val Ile Trp 370 375 380 Gln Ala Glu Arg Gly Leu Gly Gln Glu Thr Pro Val Glu Ser Leu Leu 385 390 395 400 Thr Gln Tyr Gln Asp Ala Arg Ala Gln Lys Gln Asn Thr Asp Ala Leu 405 410 415 Glu Lys Gln Ile Asn Glu Arg Leu Glu Gly Val Leu Ser Arg Trp Leu 420 425 430 Leu Leu Lys Asn Asn Thr Ile Pro Thr Ile Lys Lys Ala Leu Asn Phe 435 440 445 Asn Asn Ile His Glu Tyr Lys Gly Val Leu Asn Gly Glu Phe Asn Leu 450 455 460 Phe Asn Thr Lys Trp * 465 <210> 985 <211> 1036 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3847..6954) <400> 985 Met Val Ile Gly Pro Ala Gly Ser Gly Lys Thr Thr Leu Leu Arg Glu 1 5 10 15 Gly Phe Pro Ser Asp Ile Ile Tyr Ala Pro Glu Gly Ala Arg Gly Thr 20 25 30 Glu Gln Arg Leu Tyr Leu Thr Pro His Val Gly Lys Gln Ala Val Ile 35 40 45 Phe Asp Ile Asp Gly Thr Leu Cys Ala Pro Ala Asp Ala Asp Ile Leu 50 55 60 His Arg Arg Leu Trp Glu His Ala Leu Gly Trp Leu Lys Glu Lys Arg 65 70 75 80 Ala Arg Gln Pro Leu Asn Gly Ile Ile Leu Thr Leu Asp Leu Pro Asp 85 90 95 Leu Leu Thr Ala Asp Lys Arg His Arg Glu His Leu Leu Gln Thr Leu 100 105 110 Arg Ser Arg Leu Gln Asp Ile Arg Gln His Leu His Cys Gln Leu Pro 115 120 125 Val Tyr Val Val Leu Thr Arg Leu Asp Leu Leu Gln Gly Phe Ala Ala 130 135 140 Leu Phe Gln Ser Leu Asn Arg Gln Asp Arg Asp Ala Ile Leu Gly Val 145 150 155 160 Thr Phe Thr Arg Arg Ala His Glu Asn Asp Asp Trp Arg Thr Glu Leu 165 170 175 Asn Ala Phe Trp Gln Thr Trp Val Asp Arg Met Asn Leu Ala Leu Pro 180 185 190 Asp Leu Met Val Thr Gln Thr His Thr Arg Ala Ser Leu Phe Ser Phe 195 200 205 Ser Arg Gln Met Gln Gly Ser Arg Glu Pro Leu Val Ser Leu Leu Glu 210 215 220 Gly Leu Leu Asp Gly Glu Asn Met Asn Val Met Leu Arg Gly Val Tyr 225 230 235 240 Leu Thr Ser Ser Leu Gln Arg Gly Gln Met Asp Asp Ile Phe Thr Gln 245 250 255 Ser Ala Ala Arg Gln Tyr Arg Leu Gly Asn Asn Pro Leu Ala Ser Trp 260 265 270 Pro Leu Val Asp Thr Ala Pro Tyr Phe Thr Arg Ser Leu Phe Pro Gln 275 280 285 Ala Leu Leu Ala Glu Pro Asn Leu Ala Thr Glu Ser Arg Ala Trp Leu 290 295 300 Met Arg Ser Arg Arg Arg Leu Thr Val Phe Ser Ala Thr Gly Gly Val 305 310 315 320 Ala Ala Leu Leu Leu Ile Thr Gly Trp His His Tyr Tyr Asn Gly Asn 325 330 335 Tyr Gln Ser Gly Ile Thr Val Leu Lys Gln Ala Lys Ala Phe Met Asp 340 345 350 Val Pro Pro Pro Gln Gly Glu Asp Asp Tyr Gly Asn Leu Gln Leu Pro 355 360 365 Leu Leu Asn Pro Val Arg Asp Ala Thr Leu Ala Tyr Gly Asp Trp Gly 370 375 380 Asp Arg Ser Arg Leu Ala Asp Met Gly Leu Tyr Gln Gly Arg Arg Ile 385 390 395 400 Gly Pro Tyr Val Glu Gln Thr Tyr Leu Gln Leu Leu Glu Gln Arg Tyr 405 410 415 Leu Pro Ser Leu Phe Asn Gly Leu Val Lys Ala Met Asn Ala Ala Pro 420 425 430 Pro Glu Ser Glu Glu Lys Leu Ala Val Leu Arg Val Met Arg Met Leu 435 440 445 Glu Asp Lys Ser Gly Arg Asn Asn Glu Val Val Lys Gln Tyr Met Ala 450 455 460 Lys Arg Trp Ser Glu Lys Phe His Gly Gln Arg Asp Ile Gln Ala Gln 465 470 475 480 Leu Met Ser His Leu Asp Tyr Ala Leu Ala His Thr Asp Trp His Ala 485 490 495 Glu Arg Gln Ala Gly Asp Gly Asp Ala Ile Ser Arg Trp Thr Pro Tyr 500 505 510 Asp Lys Pro Val Val Ser Ala Gln Lys Glu Leu Ser Lys Leu Pro Val 515 520 525 Tyr Gln Arg Val Tyr Gln Ser Leu Lys Thr Arg Ala Leu Gly Val Leu 530 535 540 Pro Ala Asp Leu Asn Leu Arg Asp Gln Val Gly Pro Thr Phe Asp Gln 545 550 555 560 Val Phe Thr Ser Ala Asp Asp Asn Lys Leu Val Val Pro Gln Phe Leu 565 570 575 Thr Arg Tyr Gly Leu Gln Ser Tyr Phe Val Lys Gln Arg Asp Glu Leu 580 585 590 Val Glu Leu Thr Ala Met Asp Ser Trp Val Leu Asn Leu Thr Arg Ser 595 600 605 Val Lys Tyr Ser Asp Ala Asp Arg Ala Glu Ile Gln Arg Gln Leu Thr 610 615 620 Glu Gln Tyr Ile Ser Asp Tyr Thr Ala Thr Trp Arg Ala Gly Met Asp 625 630 635 640 Asn Leu Asn Ile Arg Asn Phe Glu Ser Ile Gly Gln Leu Thr Gly Ala 645 650 655 Leu Glu Gln Val Ile Ser Gly Asp Gln Pro Leu Gln Arg Ala Leu Thr 660 665 670 Val Leu Arg Asp Asn Thr Gln Pro Gly Val Phe Ser Glu Lys Leu Ser 675 680 685 Ala Lys Glu Arg Asp Glu Ala Leu Ala Glu Pro Asp Tyr Gln Leu Leu 690 695 700 Thr Arg Leu Gly His Glu Phe Ala Pro Glu Asn Ile Thr Leu Ala Val 705 710 715 720 Gln Lys Asp Lys Glu Ser Thr Met Gln Ala Val Tyr Gln Gln Leu Thr 725 730 735 Glu Leu His Arg Tyr Leu Leu Ala Ile Gln Asn Ala Pro Val Pro Gly 740 745 750 Lys Ser Ala Leu Lys Ala Val Gln Leu Arg Leu Asp Gln Asn Ser Ser 755 760 765 Asp Pro Ile Phe Ala Thr Arg Gln Met Ala Lys Thr Leu Pro Ala Pro 770 775 780 Leu Asn Arg Trp Val Gly Arg Leu Thr Asp Gln Ala Trp His Val Val 785 790 795 800 Met Val Glu Ala Val His Tyr Met Glu Val Asp Trp Arg Asp Ser Val 805 810 815 Val Lys Pro Phe Asn Glu Gln Leu Ala Asn Asn Tyr Pro Phe Asn Pro 820 825 830 Arg Ser Ala Gln Asp Ala Ser Leu Asp Ala Phe Glu Arg Phe Phe Lys 835 840 845 Pro Asp Gly Ile Leu Asp Thr Phe Tyr Gln Gln Asn Leu Lys Leu Phe 850 855 860 Ile Asp Asn Asp Leu Ser Leu Glu Asp Gly Asp Asn Asn Val Ile Ile 865 870 875 880 Arg Glu Asp Ile Ile Ala Gln Leu Glu Thr Ala Gln Lys Ile Arg Asp 885 890 895 Ile Phe Phe Ser Lys Gln Asn Gly Leu Gly Thr Ser Phe Ala Val Glu 900 905 910 Thr Val Ser Leu Ser Gly Asn Lys Arg Arg Ser Val Leu Asn Leu Asp 915 920 925 Gly Gln Leu Val Asp Tyr Ser Gln Gly Arg Asn Tyr Thr Ala His Leu 930 935 940 Val Trp Pro Asn Asn Met Arg Glu Gly Asn Glu Ser Lys Leu Thr Leu 945 950 955 960 Ile Gly Thr Ser Gly Asn Ala Pro Arg Ser Ile Ser Phe Ser Gly Pro 965 970 975 Trp Ala Gln Phe Arg Leu Phe Gly Ala Gly Gln Leu Thr Gly Val Gln 980 985 990 Asp Gly Asn Phe Thr Val Arg Phe Ser Val Asp Gly Gly Ala Met Thr 995 1000 1005 Tyr Arg Val His Thr Asp Thr Glu Asp Asn Pro Phe Ser Gly Gly Leu 1010 1015 1020 Phe Ser Gln Phe Gly Leu Ser Asp Thr Leu Tyr * 1025 1030 1035 <210> 986 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7211..7399) <400> 986 Val Phe Arg Leu Pro Thr Pro Arg Leu Leu Ser Gly Leu Lys Ser Ala 1 5 10 15 Leu Arg Pro Ala Met Pro Arg Phe Lys Val Ser Ala Phe Trp Leu Leu 20 25 30 Ile Leu Ala Trp Ile Phe Leu Leu Ala Asp Thr Gly Val Asp Phe Ser 35 40 45 Ala Gly Met Asp Leu Val Glu Arg Pro Asp Val Asp Ala Val * 50 55 60 <210> 987 <211> 265 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7418..8212) <400> 987 Val Thr Gln Pro Ser Ala Pro Ala Pro Gln Ile Ala Ile Asp Ser His 1 5 10 15 Asp Asp Lys Ala Trp Arg Asp Thr Leu Leu Lys Val Ala Ala Ile Leu 20 25 30 Cys Glu Arg Gln Pro Asp Ser Pro Gln Gly Tyr Arg Leu Arg Arg His 35 40 45 Ala Leu Trp Gln Ser Ile Thr Ser Thr Pro Gln Ala Glu Ser Asp Gly 50 55 60 Arg Thr Pro Leu Ala Ala Val Ser Ala Asp Met Val Ala Asp Tyr Gln 65 70 75 80 Ser Arg Leu Ala Ser Ala Asp Met Ala Leu Trp Gln Gln Val Glu Lys 85 90 95 Ser Val Leu Leu Ala Pro Tyr Trp Leu Asp Gly His Cys Leu Ser Ala 100 105 110 Gln Thr Ala Leu Arg Leu Gly Tyr Lys Gln Val Ala Asp Thr Ile Arg 115 120 125 Asp Glu Val Ile Arg Phe Leu Glu Arg Leu Pro Gln Leu Thr Gly Leu 130 135 140 Leu Phe Asn Asp Arg Thr Pro Phe Leu Ser Glu Gln Thr Lys Gln Trp 145 150 155 160 Leu Ala Ala Ser Pro Asp Gly Lys Val Ala Pro Val Ala Gln Ile Gly 165 170 175 Glu Glu Ser Gln Ala Ala Arg Ala Cys Phe Ala Gly Gln Gly Leu Glu 180 185 190 Ala Ala Leu Arg Tyr Leu Asp Met Leu Pro Glu Gly Asp Pro Arg Asp 195 200 205 Gln Phe His Arg Gln Tyr Leu Ala Ala Gln Leu Thr Glu Glu Ala Gly 210 215 220 Leu Ile Gln Leu Ala Gln Gln Gln Tyr Arg Met Leu Leu Met Ile Gly 225 230 235 240 Ser Gln Met Met Val Ser Asp Trp Glu Pro Ser Leu Leu Thr Gln Leu 245 250 255 Glu Gln Lys Phe Thr Ala Glu Gln * 260 <210> 988 <211> 207 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8209..8829) <400> 988 Met Ala Met Asp Leu Arg Asp Pro Asn Val Trp Ile Ser His Leu Leu 1 5 10 15 Glu Asn Leu Pro Glu Glu Lys Leu Ala Ser Ala Leu Lys Asp Asp Asn 20 25 30 Pro Asp Trp Glu Tyr Ile Asp Gly Glu Ile Val Lys Leu Gly Ser Leu 35 40 45 Ala His Ala Gln Leu Asp Ile Pro Glu Leu Gln Arg Arg Gly Leu Gln 50 55 60 Leu Leu Ala Ser Glu Ser Lys Asp Phe Arg Leu Leu Ala His Leu Leu 65 70 75 80 Arg Thr Leu Gln His Ala Gly Asp Pro Leu Leu Ala Leu His Leu Leu 85 90 95 Thr Leu Tyr Val Glu His Tyr Trp Thr Val Ala Ala Pro Gln Asn Met 100 105 110 Ala His Lys Lys Arg Phe Ala Ser Gln Ile Ile Lys Arg Phe Glu Thr 115 120 125 Val Leu Lys Ala Phe His Lys Thr Leu Pro Gln Arg Ser Ala Ile Leu 130 135 140 Cys Trp Val Ser Trp Arg Asn Trp Arg Ser Ala Gly Ser His Ile Thr 145 150 155 160 Ser Arg Asn Trp His Arg Leu Pro Met Ile Phe Leu Pro Cys Thr Ser 165 170 175 Val Arg Leu Ile Val Arg Leu Leu Leu Arg Ser Pro Leu Arg Arg Pro 180 185 190 Pro Val Val His His Lys Pro Pro Ser Arg Leu Lys Ala Ala * 195 200 205 <210> 989 <211> 248 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8834..9577) <400> 989 Met Ser Arg Leu Arg Val Phe Arg Gln Thr Gly Trp Phe Ile Ala Gly 1 5 10 15 Leu Met Thr Gly Leu Pro Ala Thr Ala Ala Pro Ala Glu Ala Ser Ser 20 25 30 Met Ala Gly Val Ala Val Ala Val Ala Thr Thr Thr Pro Pro Asp Ala 35 40 45 Thr Ala Thr Leu Gln Ala Met Gln Ser Cys Arg Arg Glu Ser Ala Ala 50 55 60 Leu Glu Arg Leu Asp Cys Tyr Asp His Leu Leu Ala Pro Leu Ser Pro 65 70 75 80 Ser Gly Phe Asp Gly Ala Leu Val Lys Ala Gly Phe Val Gly Glu Ala 85 90 95 Trp Thr Arg Ala Thr Glu Gln Glu Lys Arg Arg Glu Gly Asn Thr Thr 100 105 110 Glu Leu Leu Val Thr Gln Val Pro Gly Glu Arg Pro Thr Val Val Ile 115 120 125 Thr Thr Pro Ala Ile Gly His Val Pro Pro Arg Pro Val Leu Met Phe 130 135 140 Ser Cys Val Asp Asn Ile Thr Arg Met Gln Val Ala Leu Met His Pro 145 150 155 160 Leu Asp Val His Asp Ile Ala Val Thr Leu Asn Ala Asp Ser Arg Ala 165 170 175 Leu Arg Ser His Trp Phe Val Arg Glu Asn Gly Thr Leu Leu Glu Ser 180 185 190 Ser Arg Gly Leu Ser Gly Ile Asp Glu Ile Lys Gln Leu Phe Gly Ala 195 200 205 Lys Thr Leu Thr Val Asp Thr Gly Ala Asp Asn Ala Ala Gly Lys Leu 210 215 220 Thr Phe Asn Ile Asp Gly Leu Ala Arg Ala Ile Ala Pro Leu Arg Asp 225 230 235 240 Ala Cys His Trp Ala Gly Glu * 245 <210> 990 <211> 924 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9574..12345) <400> 990 Met Ile Gln Ile Asp Leu Pro Thr Leu Val Lys Arg Leu Asn Leu Phe 1 5 10 15 Ser Arg Gln Ala Leu Glu Met Ala Ala Ser Glu Cys Met Ser Gln Gln 20 25 30 Ala Ala Glu Ile Thr Val Ser His Val Leu Ile Gln Met Leu Ala Met 35 40 45 Pro Arg Ser Asp Leu Arg Val Ile Thr Arg Gln Gly Asp Ile Gly Met 50 55 60 Glu Glu Leu Arg Gln Ala Leu Thr Val Glu Asn Tyr Thr Thr Ala Arg 65 70 75 80 Ser Ala Asp Ser Tyr Pro Ala Phe Ser Pro Met Leu Val Glu Trp Leu 85 90 95 Lys Glu Gly Trp Leu Leu Ala Ser Ala Glu Met Gln His Ser Glu Leu 100 105 110 Arg Gly Gly Val Leu Leu Leu Ala Leu Leu His Ser Pro Leu Arg Tyr 115 120 125 Ile Pro Pro Ala Ala Ala Arg Leu Leu Thr Gly Ile Asn Arg Asp Arg 130 135 140 Leu Gln Gln Asp Phe Val Gln Trp Thr Gln Glu Ser Ala Glu Ser Val 145 150 155 160 Val Pro Asp Ala Asp Gly Lys Gly Ala Gly Thr Leu Thr Asp Ala Ser 165 170 175 Asp Thr Leu Leu Ala Arg Tyr Ala Lys Asn Met Thr Glu Asp Ala Arg 180 185 190 Asn Gly Arg Leu Ala Pro Val Leu Cys Arg Asp His Glu Ile Asp Leu 195 200 205 Met Ile Asp Ile Leu Cys Arg Arg Arg Lys Asn Asn Pro Val Val Val 210 215 220 Gly Glu Ala Gly Val Gly Lys Ser Ala Leu Ile Glu Gly Leu Ala Leu 225 230 235 240 Arg Ile Val Ala Gly Gln Val Pro Asp Lys Leu Lys Asn Thr Asp Ile 245 250 255 Met Thr Leu Asp Leu Gly Ala Leu Gln Ala Gly Ala Ser Val Lys Gly 260 265 270 Glu Phe Glu Lys Arg Phe Lys Gly Leu Met Ala Glu Val Ile Ser Ser 275 280 285 Pro Val Pro Val Ile Leu Phe Ile Asp Glu Ala His Thr Leu Ile Gly 290 295 300 Ala Gly Asn Gln Gln Gly Gly Leu Asp Ile Ser Asn Leu Leu Lys Pro 305 310 315 320 Ala Leu Ala Arg Gly Glu Leu Lys Thr Ile Ala Ala Thr Thr Trp Ser 325 330 335 Glu Tyr Lys Lys Tyr Phe Glu Lys Asp Ala Ala Leu Ser Arg Arg Phe 340 345 350 Gln Leu Val Lys Val Ser Glu Pro Asn Ala Ala Glu Ala Thr Ile Ile 355 360 365 Leu Arg Gly Leu Ser Ala Val Tyr Glu Arg Ser His Gly Val Leu Ile 370 375 380 Asp Asp Asp Ala Leu Gln Ala Ala Ala Thr Leu Ser Glu Arg Tyr Leu 385 390 395 400 Ser Gly Arg Gln Leu Pro Asp Lys Ala Ile Asp Val Leu Asp Thr Ala 405 410 415 Cys Ala Arg Val Ala Ile Asn Leu Ser Ser Pro Pro Lys Gln Ile Ser 420 425 430 Ala Leu Thr Thr Leu Ser His Gln Gln Glu Ala Glu Ile Arg Gln Leu 435 440 445 Glu Arg Glu Leu Arg Ile Gly Leu Arg Thr Asp Thr Ser Arg Met Thr 450 455 460 Glu Val Leu Val Gln Tyr Asp Glu Thr Leu Thr Ala Leu Asp Glu Leu 465 470 475 480 Glu Ala Ala Trp His Gln Gln Gln Thr Leu Val Arg Glu Ile Ile Ala 485 490 495 Leu Arg Gln Gln Leu Leu Gly Val Ala Glu Asp Asp Ala Ala Pro Leu 500 505 510 Pro Asp Ala Asp Thr Val Glu Asp Thr Gln Pro Glu Ser Glu Ser Glu 515 520 525 Ser Glu Gln Asp Asn Thr Gly Ala Val Pro Ala Asp Glu Thr Asp Arg 530 535 540 Glu Gln Pro Glu Glu Thr Ala Glu Thr Val Ser Pro Val Gln Arg Leu 545 550 555 560 Ala Gln Leu Thr Ala Glu Leu Asp Ala Leu His Asn Asp Arg Leu Leu 565 570 575 Val Ser Pro His Val Asp Lys Lys Gln Ile Ala Ala Val Ile Ala Glu 580 585 590 Trp Thr Gly Val Pro Leu Asn Arg Leu Ser Gln Asn Glu Met Ser Val 595 600 605 Ile Thr Asp Leu Pro Lys Trp Leu Gly Asp Thr Ile Lys Gly Gln Asp 610 615 620 Leu Ala Ile Ala Ser Leu His Lys His Leu Leu Thr Ala Arg Ala Asp 625 630 635 640 Leu Arg Arg Pro Gly Arg Pro Leu Gly Ala Phe Leu Leu Ala Gly Pro 645 650 655 Ser Gly Val Gly Lys Thr Glu Thr Val Leu Gln Leu Ala Glu Leu Leu 660 665 670 Tyr Gly Gly Arg Gln Tyr Leu Thr Thr Ile Asn Met Ser Glu Phe Gln 675 680 685 Glu Lys His Thr Val Ser Arg Leu Ile Gly Ser Pro Pro Gly Tyr Val 690 695 700 Gly Tyr Gly Glu Gly Gly Val Leu Thr Glu Ala Ile Arg Gln Lys Pro 705 710 715 720 Tyr Ser Val Val Leu Leu Asp Glu Val Glu Lys Ala His Pro Asp Val 725 730 735 Leu Asn Leu Phe Tyr Gln Ala Phe Asp Lys Gly Glu Met Ala Asp Gly 740 745 750 Glu Gly Arg Leu Ile Asp Cys Lys Asn Ile Val Phe Phe Leu Thr Ser 755 760 765 Asn Leu Gly Tyr Gln Val Ile Val Glu His Ala Asp Asp Pro Glu Thr 770 775 780 Met Gln Glu Ala Leu Tyr Pro Val Leu Ala Asp Phe Phe Lys Pro Ala 785 790 795 800 Leu Leu Ala Arg Met Glu Val Val Pro Tyr Leu Pro Leu Ser Lys Glu 805 810 815 Thr Leu Ala Thr Ile Ile Ala Gly Lys Leu Ala Arg Leu Asp Asn Val 820 825 830 Leu Arg Ser Arg Phe Gly Ala Glu Val Val Ile Glu Pro Glu Val Thr 835 840 845 Asp Glu Ile Met Ser Arg Val Thr Arg Ala Glu Asn Gly Ala Arg Met 850 855 860 Leu Glu Ser Val Ile Asp Gly Asp Met Leu Pro Pro Leu Ser Leu Leu 865 870 875 880 Leu Leu Gln Lys Met Ala Ala Asn Thr Ala Ile Ala Arg Ile Arg Leu 885 890 895 Ser Ala Val Asp Gly Ala Phe Thr Ala Asp Val Glu Asp Ala Gln Asn 900 905 910 Asp Glu Ser Val Thr Lys Asp Glu Thr Val Leu * 915 920 <210> 991 <211> 254 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12354..13115) <400> 991 Met Asp Glu Gly Ser Leu Ser Leu Pro Pro Phe Thr Gly Tyr Asp Glu 1 5 10 15 Lys Ser Leu Arg Asp Tyr His Leu Ala Leu His Gly Asn Ser Leu Asn 20 25 30 Pro Met Ile Asp Ala Ala Thr Pro Leu Leu Gly Met Val Met Arg Leu 35 40 45 Ser Thr Met Asn Ser Gln Thr Met Pro Glu His Leu Phe Ala Gln Val 50 55 60 Val Thr Asp Val Gln Ala Val Glu Gln Leu Leu Gln Glu Gln Gly Tyr 65 70 75 80 Glu Pro Gly Val Ile Ile Ser Phe Arg Tyr Ile Leu Cys Thr Phe Ile 85 90 95 Asp Glu Ala Ala Leu Gly Asn Gly Trp Ser Asn Lys Asn Glu Trp Ile 100 105 110 Lys Gln Ser Leu Leu Val His Phe His Asn Glu Ala Trp Gly Gly Glu 115 120 125 Lys Val Phe Ile Leu Leu Glu Arg Leu Ile Arg Glu Pro Lys Arg Tyr 130 135 140 Gln Asp Leu Leu Glu Phe Leu Trp Leu Cys Phe Ser Leu Gly Phe Arg 145 150 155 160 Gly Arg Tyr Lys Val Ala Val Gln Asp Gln Gly Glu Phe Glu Gln Ile 165 170 175 Tyr Arg Arg Leu Tyr His Val Leu His Lys Leu Arg Gly Asp Ala Pro 180 185 190 Phe Pro Leu Leu His Gln Asp Lys Lys Thr Gln Gly Gly Arg Tyr Gln 195 200 205 Leu Ile Ser Arg Leu Thr Val Lys His Ile Phe Cys Gly Gly Val Val 210 215 220 Val Leu Ala Leu Phe Tyr Leu Phe Tyr Leu Leu Arg Leu Asp Ser Gln 225 230 235 240 Thr Gln Asp Ile Leu His Gln Leu Asn Lys Leu Leu Arg * 245 250 <210> 992 <211> 444 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13120..14451) <400> 992 Met Ala Thr Thr Arg Asn Lys Val Met Trp Gln Glu Gly Met Leu Met 1 5 10 15 Arg Pro His His Phe Gln Gln Gln Gln Arg Tyr Asn Asp Tyr Leu Asp 20 25 30 Asn Gln Arg Phe Arg Ala Met Asn Asp Leu Ser Trp Gly Phe Thr Glu 35 40 45 Leu Thr Leu Asn Asn Glu Leu Leu Ala Gln Gly Lys Ile Met Ile Asp 50 55 60 Ser Ala Ser Gly Thr Leu Pro Asp Gly Thr Val Phe Ser Ile Pro Asp 65 70 75 80 Gln Asp Ala Leu Pro Asp Pro Leu His Pro Gln Asn Phe Pro Asp Glu 85 90 95 Arg Ser Arg Asn Ile Tyr Leu Ala Leu Pro Val Ala Ser Asp Val Arg 100 105 110 Asn Glu Ile Ser Asp Gly Arg Arg Ile Gly Arg Tyr Arg Leu Asn Tyr 115 120 125 Ala Asp Val Arg Asp Leu His Ser Glu Glu Gly Asp Ala Arg Thr Leu 130 135 140 Thr Leu Gly Gln Leu Thr Pro Arg Ile Met Ser Gly Ala Glu Asp Met 145 150 155 160 Ser Ala Tyr Ile Thr Leu Pro Leu Cys Arg Ile Ser Asp Arg His Ala 165 170 175 Asp Gly Ser Leu Thr Leu Asp Asp Asp Phe Ile Pro Ser Cys Gln Asn 180 185 190 Ile Gln Val Ser Lys Lys Leu Arg Val Tyr Leu Lys Glu Val Gln Gly 195 200 205 Ala Ile Gly Gly Arg Ala Ser Asp Leu Ala Asn Arg Ile Gly Ser Pro 210 215 220 Ala Gln Ser Gly Ile Ala Asp Val Ala Glu Phe Met Met Leu Gln Leu 225 230 235 240 Leu Asn Arg Asn Gln Thr Arg Phe Thr His Arg Ala Arg Arg Ser Gln 245 250 255 Leu His Pro Glu Asp Phe Tyr Leu Asp Leu Ala Glu Leu Leu Gly Glu 260 265 270 Leu Met Thr Phe Thr Glu Pro Ser Arg Leu Pro Cys Pro Leu Asp Val 275 280 285 Tyr Asp His His Asp Leu Thr Lys Thr Phe Lys Thr Leu Leu Pro Glu 290 295 300 Val Lys Arg Ala Leu His Thr Val Leu Ser Pro Arg Ala Val Asn Leu 305 310 315 320 Pro Leu His Leu Arg Asp Gly Ile Trp Gln Ala Asp Val His Asp Ser 325 330 335 Glu Leu Leu Gln Ser Ala Thr Phe Val Leu Ala Val Ala Ala Asn Met 340 345 350 Pro Val Asp Gln Ile Gln Arg Gln Phe Ile Gln Gln Ser Lys Ile Ser 355 360 365 Ser Pro Glu Lys Ile Arg Asn Met Val Ser Val Gln Ile Pro Gly Ile 370 375 380 Pro Leu Arg Ala Leu Met Val Ala Pro Arg Gln Leu Pro Tyr His Ser 385 390 395 400 Gly Phe Ser Tyr Phe Glu Leu Asp Lys Ser Gly Gln Ala Trp Thr Glu 405 410 415 Met Ala Ala Ala Gly Ala Val Ala Leu His Val Ser Gly Ser Phe Pro 420 425 430 Asp Leu Asn Met Gln Leu Trp Ala Ile Arg Gly * 435 440 <210> 993 <211> 175 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14454..14978) <400> 993 Met Asn Arg Lys Ala Phe Leu Ala Cys Val Leu Met Cys Val Ile Leu 1 5 10 15 Thr Gly Cys Glu Thr Ala Lys Lys Ile Ser Glu Val Ile Lys Asn Pro 20 25 30 Asp Ile Gln Val Gly Ser Leu Lys Glu Gln Pro Ser Glu Ile Thr Val 35 40 45 Thr Leu Leu Thr Glu Pro Asp Thr Asn Thr Asn Ala Glu Gly Glu Ser 50 55 60 Ala Ala Val Asp Val Gln Leu Val Tyr Leu Thr Asp Asp Ser Lys Leu 65 70 75 80 Gln Ala Ala Asp Tyr Asp Gln Ile Ala Ser Thr Pro Leu Pro Asp Val 85 90 95 Leu Gly Lys Asn Tyr Ile Asp His Gln Asp Phe Asn Leu Leu Pro Asp 100 105 110 Thr Ile Lys Thr Leu Pro Pro Ile Lys Leu Asp Glu Lys Thr Gln Phe 115 120 125 Ile Gly Val Val Ala Tyr Phe Ser Asp Asp Gln Ala Thr Glu Trp Lys 130 135 140 Gln Ile Glu Thr Val Glu Gly Thr Gly His His Tyr Arg Leu Leu Val 145 150 155 160 His Val Arg Gln Ser Ser Ile Glu Met Lys Lys Glu Asp Glu * 165 170 <210> 994 <211> 427 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14975..16255) <400> 994 Met Pro Glu Glu Lys Leu Gln Thr Leu Ser Leu Gln Val Ile Asn Gly 1 5 10 15 Ser Glu Leu Glu Ser Gly Arg Ala Ala Arg Cys Leu Phe Thr Gln Gln 20 25 30 Gly Asn Val Gly His Ala Pro Glu Cys His Trp Ser Val Gln Asp Arg 35 40 45 Gln Gln Ser Ile Pro Ala Gln Ala Phe Thr Val Ile Leu His Asp Gly 50 55 60 Thr Phe Cys Leu Arg Pro Gln Thr Ala Gln Leu Trp Leu Asn Gln Ala 65 70 75 80 Lys Val Thr Ala Thr Ser Asp Leu Ile Gln Leu Arg Gln Gly Asp Glu 85 90 95 Ile Gln Ile Gly Arg Leu Met Val Arg Val His Leu Asn Arg Gly Asp 100 105 110 Ile Pro His Tyr Asp Glu Glu Met Ala Thr Pro Glu Thr Ile Val Thr 115 120 125 Asn Arg Asp Met Leu Thr Asp Thr Leu Leu Ser Thr Glu Gly Ala Pro 130 135 140 His Tyr Pro Gly Met Thr His Arg His Gln Leu Ala Asp Thr Val Val 145 150 155 160 Asn Gly Phe Ser Ala Asp Pro Leu Gln Ala Leu Gln Ser Glu Ser Leu 165 170 175 Ile Thr Thr Gly Asp Pro Leu Ser Gly Ile Ala Ala Val Arg Pro Ser 180 185 190 Ala Pro Leu Ser Asp Pro Ala Ser Asn Gly Gly Ile Asn Thr Pro Phe 195 200 205 Met Asp Leu Pro Pro Ile Tyr Ala Ser Pro Gly Asp His Asn Asp Asp 210 215 220 Ile Ser Ala Ala Glu Met Ala Gln Arg His Leu Ala Val Thr Pro Leu 225 230 235 240 Leu Arg Gly Leu Gly Gly Ser Leu Thr Val Ser Asn Ser Asp Asp Ala 245 250 255 Asp Asp Phe Leu Glu Glu Ala Gly Arg Thr Leu Gln Ala Ala Ile Lys 260 265 270 Gly Leu Leu Asp Leu Gln Gln Gln Arg Asn Ser Leu Ser Asp Lys His 275 280 285 Leu Arg Pro Leu Glu Asp Asn Pro Leu Arg Leu Asn Met Asp Tyr Ala 290 295 300 Thr Ala Leu Asp Val Met Phe Ala Glu Gly Lys Ser Pro Val His Leu 305 310 315 320 Ala Ala Pro Ala Ala Val Ser Glu Ser Leu Arg Asn Val Arg His His 325 330 335 Glu Glu Ala Asn Arg Ala Ala Ile Val Glu Ser Leu Arg Val Leu Leu 340 345 350 Asp Ala Phe Ser Pro Gln Asn Leu Leu Arg Arg Phe Val Gln Tyr Arg 355 360 365 Arg Ser His Glu Leu Arg Gln Pro Leu Asp Asp Ala Gly Ala Trp Gln 370 375 380 Met Tyr Ser His Tyr Tyr Glu Glu Leu Ala Ser Asp Arg Gln Gln Gly 385 390 395 400 Phe Glu Met Leu Phe Asn Glu Val Tyr Ala Gln Val Tyr Asp Arg Val 405 410 415 Leu Arg Glu Lys Gln Arg Glu Pro Glu Ala * 420 425 <210> 995 <211> 361 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16280..17362) <400> 995 Met Asp Gly Lys Asn Arg Ala Ala Ser Ser Tyr Leu Ser Pro Gly Asn 1 5 10 15 Pro Pro Ala Asp Lys Glu Gln Asn Asp Pro Leu Ala Gln Val Phe His 20 25 30 Asn Ala Cys Ser Tyr Asn Phe Phe Ala Met Ala Glu Leu Leu His Arg 35 40 45 Leu Ala Lys Gly Glu Lys Gly Thr Pro Glu Leu Ser Leu Arg Asp Asp 50 55 60 Pro Ala Gln Glu Thr Leu Arg Phe Ser Ala Asp Ala Ser Leu Ala Phe 65 70 75 80 Pro Cys Ser Asp Ile Ser Ala Leu Lys Arg Asp Thr Ser Gly Ala Phe 85 90 95 Arg Met Thr Thr Thr Phe Met Gly Leu Gln Gly Ser Gln Ser Pro Leu 100 105 110 Pro Gly Tyr Tyr Leu Asp His Leu Ala Trp Lys Ala Val His Glu Gln 115 120 125 Ser Pro Val Gly Asp Phe Leu Asp Met Phe Ser His Arg Leu Thr Gln 130 135 140 Phe Val Trp His Ile Trp Arg Lys Tyr Arg Tyr His Ile Ser Phe Arg 145 150 155 160 Asn Gly Gly Val Asp Ala Phe Ser Gln Arg Met Tyr Ser Leu Val Gly 165 170 175 Leu Gly His Arg Gln Leu Arg Asp Lys Leu Ala Ile Asn His Ser Lys 180 185 190 Met Leu Ala Tyr Ser Gly Ile Leu Ala Asn Pro Gly Arg Ser Pro Glu 195 200 205 Ile Ile Cys Gly Leu Val Ser His Cys Phe Asp Leu Ser Glu Val Thr 210 215 220 Leu Gln Asn Trp Gln Arg Arg Lys Val Asp Ile Glu Pro Asp Gln Gln 225 230 235 240 Asn Ser Leu Gly Ser Tyr Ser Leu Lys Asn Gly Glu Lys Leu Ala Gly 245 250 255 Arg Ser Val Leu Gly Asn Phe Val Leu Gly Thr Arg Val Pro Asp Leu 260 265 270 Ser Gly Lys Phe Gln Leu Ser Ile Thr Ser Leu Thr Arg Lys Gln Phe 275 280 285 Leu Ser Phe Leu Pro Ser Gly Glu Asn Phe Leu Pro Leu Thr Thr Phe 290 295 300 Val Ser Phe Ile Leu Arg Asp Gln Leu Ala Trp Asp Leu His Leu Gly 305 310 315 320 Leu Ala Pro Glu Gln Val Gly Ala Met Arg Leu Gly Asp Asn Lys Ser 325 330 335 Ala Leu Leu Gly Trp Thr Ser Phe Leu Gly Thr Pro Glu Glu Arg Pro 340 345 350 Ser Val Thr Ile Arg Val Arg Ser * 355 360 <210> 996 <211> 617 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17326..19176) <400> 996 Met Glu Phe Glu Glu Arg Tyr Phe Arg Glu Glu Leu Asp Tyr Leu Arg 1 5 10 15 Gln Leu Ser Lys Leu Leu Ala Thr Glu Lys Pro His Leu Ala Arg Phe 20 25 30 Leu Ala Glu Lys Asp Ala Asp Pro Asp Ile Glu Arg Leu Leu Glu Gly 35 40 45 Val Ala Phe Leu Thr Gly Asn Leu Arg Gln Lys Ile Glu Asp Glu Phe 50 55 60 Pro Glu Leu Thr His Gly Leu Ile Lys Met Leu Trp Pro Asn Tyr Leu 65 70 75 80 Arg Pro Val Pro Ala Met Thr Leu Ile Glu Tyr Thr Pro Asp Met Asp 85 90 95 Lys Ser Ser Val Pro Val Leu Ile Pro Arg Asn Glu Gln Phe Thr Thr 100 105 110 Asn Ala Gly Glu Ile Arg Val Asp Glu Val Leu Pro Ser Asp Ala Lys 115 120 125 Lys Glu Glu Pro Pro Pro Cys Thr Phe Thr Leu Cys Arg Asp Ile Trp 130 135 140 Leu Leu Pro Val Arg Leu Glu Gln Ile Glu Asn Arg Ser Thr Thr Arg 145 150 155 160 Asn Gly Val Ile Asn Ile Thr Phe Ser Val Ala Pro Gly Thr Asp Phe 165 170 175 Arg Thr Leu Asp Leu Asn Lys Leu Arg Phe Trp Leu Gly Asn Asp Asp 180 185 190 Asn Tyr Thr Arg Asp Gln Leu Tyr Leu Trp Phe Cys Glu Tyr Leu Gln 195 200 205 Gly Ala Asp Leu Thr Val Gly Glu Gln His Ile Arg Leu Pro Glu Phe 210 215 220 Met Leu Lys Ala Val Gly Phe Glu Pro Gln Asp Ala Met Leu Pro Trp 225 230 235 240 Pro Lys Asn Val His Ser Gly Tyr Arg Ile Leu Gln Glu Tyr Phe Cys 245 250 255 Tyr Pro Asp Ala Phe Leu Phe Phe Asp Leu Cys Gly Cys Pro Ala Leu 260 265 270 Pro Asp Gly Leu Gln Ala Glu Phe Phe Thr Leu Gln Leu Arg Phe Ser 275 280 285 Arg Pro Leu Pro Val Asp Ile Arg Leu Arg Arg Asp Ser Leu Arg Leu 290 295 300 Tyr Cys Ala Pro Ala Ile Asn Leu Phe Ile His His Ala Glu Ala Ile 305 310 315 320 Thr Leu Asp Asn Arg Arg Ala Asp Tyr Pro Leu Val Pro Ser Arg His 325 330 335 Tyr Pro Gln His Tyr Asp Val Phe Ser Val Asn Ser Val Val Ser Gln 340 345 350 Val Gln Asp Met Phe Arg Lys Lys Asp Leu Gly Arg Pro Val Ser Thr 355 360 365 Gln Ala Ala Arg Gln Trp Pro Ala Phe Glu Ser Phe Ser His Gln Met 370 375 380 Glu Tyr Ser Arg Lys Arg Glu Val Val Tyr Trp His His Arg Thr Lys 385 390 395 400 Thr Ser Leu Phe His Arg Gly Phe Asp His Thr Leu Ala Phe Ile His 405 410 415 Ala Asp Gly Ser Tyr Pro Ser Asp Glu Ser Leu Leu Ser Asn Glu Val 420 425 430 Val Ser Val Ser Leu Thr Cys Thr Asn Arg Glu Leu Pro Ser Gln Ile 435 440 445 Arg Ser Gly Asp Ile Thr Gly Thr Thr Gly Lys Asn Ala Ala Val Ala 450 455 460 Ser Phe Arg Asn Ile Thr Arg Pro Thr Gln Pro Leu Trp Pro Val Ile 465 470 475 480 Asp Gly Ser Leu His Trp Ser Leu Leu Ser Ala Met Asn Leu Asn Tyr 485 490 495 Leu Ser Leu Leu Asp Thr Asp Ala Leu Lys Gln Val Ile Ala Asn Phe 500 505 510 Asp Arg His Ala Ile His His Pro Gln Thr Ala Arg Leu Ser Gln Gln 515 520 525 Lys Leu Asp Ala Ile Glu Arg Leu Glu Thr Arg Pro Val Asp Arg Leu 530 535 540 Phe Thr Gly Ile Pro Val Arg Gly Leu Ala Ser Thr Leu Tyr Leu His 545 550 555 560 Pro Glu Pro Phe Val Cys Glu Gly Glu Met Tyr Leu Leu Gly Thr Val 565 570 575 Leu Ser His Phe Leu Ser Leu Tyr Ala Ser Val Asn Ser Phe His Met 580 585 590 Leu Thr Val Val Asn Thr Glu Ser Gln Glu Thr Trp Lys Trp Thr Glu 595 600 605 Arg Ile Gly Gln His Pro Leu Ile * 610 615 <210> 997 <211> 138 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19180..19593) <400> 997 Met Ile Leu Asp Arg Glu Arg Thr Thr Gly Ser Leu Phe Glu Arg Met 1 5 10 15 Glu Ala Ser Ser Ala Arg Asn Arg Gln Gly Gly Ser Ile His Ser Leu 20 25 30 Arg Gln Ser Ile Arg Gln Asn Leu Arg Asn Ile Leu Asn Thr Arg Ser 35 40 45 Gly Ser Cys Arg Gly Ala Pro Glu Leu Gly Ile Asp Glu Pro Glu Gly 50 55 60 Ala Glu Asn Phe Arg Glu Ser Met Ser Arg Ala Ile Glu Gln Cys Ile 65 70 75 80 Glu Arg Tyr Glu Pro Arg Ile Ser His Ala Glu Val Gln Ala Val Val 85 90 95 Ser Ser Ala Ser Ser Pro Leu Asp Met Thr Phe His Ile Thr Ala Trp 100 105 110 Val Thr Phe Asn Glu Thr His Glu Val Leu Glu Phe Asp Met Ala Pro 115 120 125 Asn Gly Ser Gln His Tyr Arg Val Asp * 130 135 <210> 998 <211> 464 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19684..21075) <400> 998 Met Ser Leu Gln Glu Glu Glu Leu Val Ser Ser His Ala Gly Gln Pro 1 5 10 15 Glu Gln Glu Ser Ser Leu Leu Asp Gln Ile Met Ala Gln Thr Arg Ile 20 25 30 Gln Pro Gly Ser Glu Gly Tyr Asp Val Ala Arg Gln Gly Val Thr Ala 35 40 45 Phe Ile Ala Ser Ile Leu Gln Ser Thr Ala Ser Ala Glu Pro Val Asn 50 55 60 Lys Leu Ala Val Asp Ser Met Ile Ala Asp Ile Asp Glu Arg Ile Ser 65 70 75 80 Arg Gln Met Asp Val Ile Ile His Ala Pro Ala Phe Gln Gln Val Glu 85 90 95 Ser Phe Trp Arg Ser Leu Lys Thr Met Val Asp Arg Val Asp Phe Arg 100 105 110 Glu Asn Ile Lys Val Asn Val Leu His Val Thr Lys Gln Glu Leu Leu 115 120 125 Glu Asp Phe Glu Phe Ala Pro Glu Ile Ile Gln Ser Gly Phe Tyr Lys 130 135 140 His Val Tyr Ser Ser Gly Phe Gly Gln Phe Gly Gly Glu Pro Ile Ala 145 150 155 160 Ala Val Leu Gly Ala Tyr Glu Phe Lys Asn Thr Ala Pro Asp Met Lys 165 170 175 Leu Leu Gln Tyr Val Ser Ala Val Gly Ala Met Ala His Ala Pro Phe 180 185 190 Leu Ser Ser Val Ser Pro Glu Phe Met Gly Leu Asn Ser Trp Thr Glu 195 200 205 Leu Pro Asn Ile Lys Asp Leu Tyr Ala Ile Phe Glu Gly Pro Ala Tyr 210 215 220 Thr Lys Trp Arg Ala Leu Arg Asp Ser Glu Asp Ser Arg Tyr Leu Gly 225 230 235 240 Leu Thr Ala Pro Arg Phe Leu Leu Arg Gln Pro Tyr Ser Pro Thr Asp 245 250 255 Asn Pro Val Lys Asn Phe Asn Tyr Tyr Glu Asp Val Ser Gln Asn His 260 265 270 Glu Asp Tyr Leu Trp Gly Asn Thr Ala Trp Met Leu Ala Cys Asn Ile 275 280 285 Ala Asp Ser Phe Ala Lys Tyr Arg Trp Cys Pro Asn Ile Ile Gly Pro 290 295 300 Gln Ser Gly Gly Ala Val Lys Asp Leu Pro Val His Leu Phe Glu Thr 305 310 315 320 Met Gly Gln Ile Gln Ala Lys Ile Pro Thr Glu Val Leu Val Thr Asp 325 330 335 Arg Arg Glu Phe Glu Leu Ala Glu Glu Gly Phe Ile Thr Leu Thr Met 340 345 350 Arg Lys Asp Ser Asp Asn Ala Ala Phe Phe Ser Ala Asn Ser Val Gln 355 360 365 Lys Pro Lys His Phe Pro Gly Lys Asp Ala Glu Thr Asn Tyr Lys Leu 370 375 380 Gly Thr Gln Leu Pro Tyr Leu Phe Ile Ile Asn Arg Leu Ala His Tyr 385 390 395 400 Ile Lys Val Leu Gln Arg Glu Gln Leu Gly Ser Trp Lys Glu Arg Ser 405 410 415 Asp Leu Glu Arg Glu Leu Asn Thr Trp Ile Arg Gln Tyr Val Ala Asp 420 425 430 Gln Glu Asn Pro Pro Ala Asp Val Arg Ser Arg Lys Pro Leu Arg Ala 435 440 445 Ala Lys Val Glu Val Met Asp Val Glu Gly Glu Pro Gly Trp Tyr * 450 455 460 <210> 999 <211> 75 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21126..21350) <400> 999 Met Thr Ala His Lys Asn Ile Ser Gly Thr Tyr His Leu Ser Val Ala 1 5 10 15 Asp Ile Leu Gln Val Val Tyr Gln Val Cys Phe Ser Pro Ser Val Glu 20 25 30 Ile Asn Gln Asp Gly Val Ala Ala Leu Ile Thr Thr Leu Asp Arg Arg 35 40 45 Ile Ser Asp Leu Leu Asp Glu Ile Ile His Phe Cys Glu Phe Gln Gln 50 55 60 Ser Ala Ser His Trp Gln Arg Val Leu His * 65 70 <210> 1000 <211> 167 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21385..21885) <400> 1000 Met Ser Lys Lys Phe Glu Gly Ser Val Ala Pro Arg Glu Arg Ile Asn 1 5 10 15 Ile Ser Tyr Val Pro Lys Thr Asp Gly Gln Thr Ala Glu Val Glu Leu 20 25 30 Pro Leu Asn Met Leu Val Val Gly Asp Thr Gly Asn Thr Gln Glu Thr 35 40 45 Ser Ser Leu Asp Glu Arg Gln Ala Val Ser Val Asn Lys His Asn Phe 50 55 60 Gly Ala Val Met Ala Glu Ala Ala Ile Gly Leu Asn Phe Thr Val Pro 65 70 75 80 Ala Thr Leu Lys Gly Ser Thr Thr Asp Asp Glu Met Asn Val Ala Leu 85 90 95 Asn Ile Lys Ser Leu Asp Asp Phe Ser Pro Asp Ser Val Ala Arg Gln 100 105 110 Val Pro Glu Val Asn Lys Leu Leu Glu Leu Arg Glu Ala Leu Thr Ala 115 120 125 Leu Lys Gly Pro Met Gly Asn Leu Pro Ala Phe Arg Thr Gln Leu Gln 130 135 140 Ala Leu Leu Glu Asn Glu Glu Ser Arg Glu Gln Leu Leu Lys Glu Ile 145 150 155 160 Gly Gln Val Ser Asn Lys * 165 <210> 1001 <211> 173 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22582..23100) <400> 1001 Met Pro Thr Pro Cys Tyr Ile Ser Ile Thr Gly Gln Thr Gln Gly Asn 1 5 10 15 Ile Thr Ala Gly Ala Phe Thr Ala Asp Ser Val Gly Asn Ile Tyr Val 20 25 30 Gln Gly His Glu Asp Glu Met Leu Val Gln Glu Phe Leu His Asn Val 35 40 45 Thr Val Pro Thr Asp Pro Gln Ser Gly Gln Pro Ala Gly Gln Arg Ala 50 55 60 His Lys Pro Phe Ile Phe Thr Val Ala Leu Asn Lys Ala Val Pro Leu 65 70 75 80 Met Tyr Asn Ala Leu Ala Ser Gly Glu Met Leu Pro Thr Thr Glu Leu 85 90 95 His Trp Trp Arg Thr Ser Val Glu Gly Lys Gln Glu His Tyr Phe Thr 100 105 110 Thr Arg Leu Thr Asp Ser Thr Ile Val Asp Met Lys Leu His Met Pro 115 120 125 His Cys Gln Asp Pro Ala Lys Arg Glu Phe Thr Gln Leu Leu Glu Val 130 135 140 Ser Leu Ala Tyr Arg Lys Ile Glu Trp Glu His Val Lys Ser Gly Thr 145 150 155 160 Ser Gly Ala Asp Asp Trp Arg Ala Pro Leu Glu Ala * 165 170 <210> 1002 <211> 46 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23133..23270) <400> 1002 Met Leu Phe Leu Tyr Tyr Ala Val Glu Arg Lys Val Val Ser Lys Gly 1 5 10 15 Leu Arg Ser Arg Glu Met Ala Ala Ala Gly Asn Phe Gly Gly Ser Val 20 25 30 Pro Glu Arg Lys Arg Ser Thr Val Leu Ser Gln Pro Leu * 35 40 45 <210> 1003 <211> 714 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23310..25451) <400> 1003 Met Ser Thr Gly Leu Arg Phe Thr Leu Glu Val Asp Gly Leu Pro Pro 1 5 10 15 Asp Ala Phe Ala Val Val Phe Phe His Leu Asn Gln Ser Leu Ser Ser 20 25 30 Leu Phe Ser Leu Ala Leu Ser Leu Val Ser Gln Gln Phe Leu Ser Leu 35 40 45 Glu Phe Gln Gln Ile Leu Asp Lys Met Ala Tyr Leu Thr Ile Trp Gln 50 55 60 Gly Asp Asp Val Gln Arg Arg Val Lys Gly Val Val Thr Trp Phe Glu 65 70 75 80 Leu Gly Glu Asn Asp Lys Asn Gln Lys Leu Tyr Ser Met Lys Val Cys 85 90 95 Pro Pro Leu Trp Arg Thr Gly Leu Arg Gln Asn Phe Arg Ile Phe Gln 100 105 110 Asn Glu Asp Ile Ala Ser Ile Leu Gly Thr Ile Leu Gln Glu Asn Gly 115 120 125 Val Thr Glu Trp Ser Pro Leu Phe Ser Glu Pro His Pro Ser Arg Glu 130 135 140 Phe Cys Val Gln Tyr Gly Glu Thr Asp Tyr Asp Phe Leu Cys Arg Met 145 150 155 160 Ala Ala Glu Glu Gly Ile Phe Phe Tyr Glu Glu His Ala Gln Lys Ser 165 170 175 Thr Asp Gln Ser Leu Val Leu Cys Asp Thr Val Leu Tyr Leu Pro Glu 180 185 190 Ser Phe Glu Ile Pro Trp Asn Pro Asn Thr Arg Thr Glu Val Ser Thr 195 200 205 Leu Cys Ile Ser Gln Phe Arg Tyr Ser Ala Gln Ile Arg Pro Ser Ser 210 215 220 Val Val Thr Lys Asp Tyr Thr Phe Lys Arg Pro Gly Trp Ala Gly Arg 225 230 235 240 Phe Asp Gln Glu Gly Gln His Gln Asp Tyr Gln Arg Thr Gln Tyr Glu 245 250 255 Val Tyr Asp Tyr Pro Gly Arg Phe Lys Gly Ala His Gly Gln Asn Phe 260 265 270 Ala Arg Trp Gln Met Asp Gly Trp Arg Asn Asn Ala Glu Val Ala Arg 275 280 285 Gly Thr Ser Arg Ser Pro Glu Ile Trp Pro Gly Arg Arg Ile Val Leu 290 295 300 Thr Gly His Pro Gln Ala Asn Leu Asn Arg Glu Trp Gln Val Val Ala 305 310 315 320 Ser Glu Leu His Gly Glu Gln Pro Gln Ala Val Pro Gly Arg Arg Gly 325 330 335 Ser Gly Thr Thr Leu Asp Asn His Phe Ala Val Ile Pro Ala Asp Arg 340 345 350 Thr Trp Arg Pro Gln Pro Leu Leu Lys Pro Leu Val Asp Gly Pro Gln 355 360 365 Ser Ala Val Val Thr Gly Pro Ala Gly Glu Glu Ile Phe Cys Asp Glu 370 375 380 His Gly Arg Val Arg Val Lys Phe Asn Trp Asp Arg Tyr Asn Pro Ser 385 390 395 400 Asn Gln Asp Ser Ser Cys Trp Ile Arg Val Ala Gln Ala Trp Ala Gly 405 410 415 Thr Gly Phe Gly Asn Leu Ala Ile Pro Arg Val Gly Gln Glu Val Ile 420 425 430 Val Asp Phe Leu Asn Gly Asp Pro Asp Gln Pro Ile Ile Met Gly Arg 435 440 445 Thr Tyr His Gln Glu Asn Arg Thr Pro Gly Ser Leu Pro Gly Thr Lys 450 455 460 Thr Gln Met Thr Ile Arg Ser Lys Thr Tyr Lys Gly Ser Gly Phe Asn 465 470 475 480 Glu Leu Lys Phe Asp Asp Ala Thr Gly Lys Glu Gln Val Tyr Ile His 485 490 495 Ala Gln Lys Asn Met Asn Thr Glu Val Leu Asn Asn Arg Thr Thr Asp 500 505 510 Val Ile Asn Asn His Ala Glu Lys Ile Gly Asn Asn Gln Ala Ile Thr 515 520 525 Val Thr Asn Asn Gln Ile Leu Asn Ile Gly Val Asn Gln Ile Gln Thr 530 535 540 Val Gly Val Asn Gln Val Glu Thr Val Gly Ser Asn Gln Ile Ile Lys 545 550 555 560 Val Gly Ser Asn Gln Val Glu Lys Val Gly Ile Ile Arg Ala Leu Thr 565 570 575 Val Gly Val Ala Tyr Gln Thr Thr Val Gly Gly Ile Met Asn Thr Ser 580 585 590 Val Ala Leu Leu Gln Ser Ser Gln Val Gly Leu His Lys Ser Leu Met 595 600 605 Val Gly Met Gly Tyr Ser Val Asn Val Gly Asn Asn Val Thr Phe Ser 610 615 620 Val Gly Lys Thr Met Lys Glu Asn Thr Gly Gln Thr Ala Val Tyr Ser 625 630 635 640 Ala Gly Glu His Leu Glu Leu Cys Cys Gly Lys Ala Arg Leu Val Leu 645 650 655 Thr Lys Asp Gly Ser Ile Phe Leu Asn Gly Thr His Ile His Leu Glu 660 665 670 Gly Glu Ser Asp Val Asn Gly Asp Ala Pro Val Ile Asn Trp Asn Cys 675 680 685 Gly Ala Thr Gln Pro Val Pro Asp Ala Pro Val Pro Lys Asp Leu Pro 690 695 700 Pro Gly Met Pro Asp Met Arg Gln Phe * 705 710 <210> 1004 <211> 1405 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25527..29741) <400> 1004 Met Gly Gly Lys Pro Ala Ala Arg Gln Gly Asp Met Thr Arg Lys Gly 1 5 10 15 Leu Asp Ile Val Gln Gly Ser Ala Gly Val Leu Ile Gly Ala Pro Thr 20 25 30 Gly Val Ala Cys Ser Val Cys Pro Gly Gly Ile Thr Tyr Ala Asn Pro 35 40 45 Val Asn Pro Val Leu Gly Ala Lys Val Leu Pro Gly Glu Thr Asp Leu 50 55 60 Ala Leu Pro Gly Pro Leu Pro Phe Ile Leu Ser Arg Ala Tyr Ser Ser 65 70 75 80 Tyr Arg Thr Arg Thr Pro Ala Pro Val Gly Val Phe Gly Pro Gly Trp 85 90 95 Lys Ala Pro Phe Asp Ile Arg Leu Gln Ile Arg Asp Glu Gly Leu Ile 100 105 110 Leu Asn Asp Asn Gly Gly Arg Ser Ile His Phe Glu Pro Leu Phe Pro 115 120 125 Gly Glu Ile Ser Tyr Ser Arg Ser Glu Ser Phe Trp Leu Ala Arg Gly 130 135 140 Gly Val Ala Glu Gln His Ser Ser Gln Pro Leu Ser Ala Leu Trp Gln 145 150 155 160 Val Leu Pro Glu Asp Val Arg Leu Ser Pro His Met Tyr Leu Ala Thr 165 170 175 Asn Ser Leu Gln Gly Pro Trp Trp Ile Leu Asn Trp Pro Glu Arg Val 180 185 190 Pro Gly Ala Asp Glu Val Leu Pro Pro Glu Pro Pro Ala Tyr Arg Val 195 200 205 Leu Thr Gly Val Val Asp Gly Phe Gly Arg Thr Leu Ala Phe His Arg 210 215 220 Ala Ala Glu Gly Asp Val Ala Gly Ala Val Thr Gly Val Thr Asp Gly 225 230 235 240 Ala Gly Arg Arg Phe His Leu Val Leu Thr Thr Gln Ala Gln Arg Ala 245 250 255 Glu Val Phe Arg Lys Gln Arg Ala Thr Ser Leu Ser Ser Pro Ala Gly 260 265 270 Pro Arg Ser Ala Ser Ser Ser Leu Val Phe Pro Asp Thr Leu Pro Ala 275 280 285 Gly Thr Glu Tyr Gly Ala Asp Asn Gly Ile Arg Leu Glu Ala Val Trp 290 295 300 Leu Thr His Asp Pro Ala Tyr Pro Asp Glu Leu Pro Ala Ala Pro Leu 305 310 315 320 Ala Arg Tyr Thr Tyr Thr Ala Ser Gly Glu Leu Arg Ala Val Tyr Asp 325 330 335 Arg Ser Gly Thr Gln Val Arg Gly Phe Ala Tyr Asp Ala Glu His Ala 340 345 350 Gly Arg Met Val Ala His His Tyr Ala Gly Arg Pro Glu Ser Arg Tyr 355 360 365 Arg Tyr Asp Asp Thr Gly Arg Val Thr Glu Leu Val Asn Pro Glu Gly 370 375 380 Leu Asp Tyr Arg Phe Glu Tyr Gly Gln Asp Arg Val Thr Ile Thr Asp 385 390 395 400 Ser Leu Asn Arg Arg Glu Val Leu Tyr Thr Glu Gly Glu Gly Gly Leu 405 410 415 Lys Arg Val Val Lys Lys Glu His Ala Asp Gly Ser Ile Thr Arg Ser 420 425 430 Glu Tyr Asp Glu Ala Gly Arg Leu Lys Ala Gln Thr Asp Ala Ala Gly 435 440 445 Arg Arg Thr Glu Tyr Ser Leu His Met Ala Ser Gly Ala Val Thr Ala 450 455 460 Val Thr Gly Pro Asp Gly Arg Thr Val Arg Tyr Gly Tyr Asn Ser Gln 465 470 475 480 Arg Gln Val Thr Ser Val Thr Tyr Pro Asp Gly Leu Arg Ser Ser Arg 485 490 495 Glu Tyr Asp Glu Lys Gly Arg Leu Ala Ala Glu Thr Ser Arg Ser Gly 500 505 510 Glu Thr Thr Arg Tyr Ser Tyr Asp Asp Pro Ala Ser Glu Leu Pro Thr 515 520 525 Gly Ile Gln Asp Ala Thr Gly Ser Thr Lys Gln Met Ala Trp Ser Arg 530 535 540 Tyr Gly Gln Leu Leu Thr Phe Thr Asp Cys Ser Gly Tyr Thr Thr Arg 545 550 555 560 Tyr Glu Tyr Asp Arg Tyr Gly Gln Gln Ile Ala Val His Arg Glu Glu 565 570 575 Gly Ile Ser Thr Tyr Ser Ser Tyr Asn Pro Arg Gly Gln Leu Val Ser 580 585 590 Gln Lys Asp Ala Gln Gly Arg Glu Thr Arg Tyr Glu Tyr Ser Ala Ala 595 600 605 Gly Asp Leu Thr Ala Ile Val Ala Pro Asp Gly Ser Arg Ser Glu Ile 610 615 620 Gln Tyr Asp Ala Trp Gly Lys Ala Val Ser Thr Thr Gln Gly Gly Leu 625 630 635 640 Thr Arg Ser Met Gly Tyr Asp Ala Ala Gly Arg Ile Thr Val Leu Thr 645 650 655 Asn Glu Asn Gly Ser Gln Ser Thr Phe Arg Tyr Asp Pro Val Asp Arg 660 665 670 Leu Thr Glu Gln Arg Gly Phe Asp Gly Arg Thr Gln Arg Tyr His Tyr 675 680 685 Asp Leu Thr Gly Lys Leu Thr Gln Ser Glu Asp Glu Gly Leu Val Thr 690 695 700 Leu Trp His Tyr Asp Ala Ser Asp Arg Ile Thr His Arg Thr Val Asn 705 710 715 720 Gly Asp Pro Ala Glu Gln Trp Gln Tyr Asp Glu His Gly Trp Leu Thr 725 730 735 Thr Leu Ser His Thr Ser Glu Gly His Arg Val Ser Val His Tyr Gly 740 745 750 Tyr Asp Asp Lys Gly Arg Leu Thr Gly Glu Arg Gln Thr Val Glu Asn 755 760 765 Pro Glu Thr Gly Glu Met Leu Trp Glu His Glu Thr Gly His Ala Tyr 770 775 780 Ser Glu Gln Gly Leu Ala Thr Arg Gln Glu Pro Asp Gly Leu Pro Pro 785 790 795 800 Val Glu Trp Leu Thr Tyr Gly Ser Gly Tyr Leu Ala Gly Met Lys Leu 805 810 815 Gly Gly Thr Pro Leu Val Glu Tyr Met Arg Asp Arg Leu His Arg Glu 820 825 830 Thr Ala Arg Ser Phe Gly Gly Glu Ala Tyr Glu Leu Ala Thr Ala Trp 835 840 845 Asn Thr Ser Gly Gln Leu Arg Ser Arg His Leu Asn Leu Pro Gln Leu 850 855 860 Asp Arg Asp Tyr Asp Trp Asn Asp Asn Gly Gln Leu Ile Arg Ile Ser 865 870 875 880 Gly Pro Gln Glu Ser Arg Glu Tyr Arg Tyr Ser Asp Thr Gly Arg Leu 885 890 895 Thr Gly Val His Thr Thr Ala Ala Asn Leu Asp Ile Asp Ile Pro Tyr 900 905 910 Ala Thr Asp Pro Ala Gly Asn Arg Leu Pro Asp Pro Glu Leu His Pro 915 920 925 Asp Ser Thr Leu Thr Ala Trp Pro Asp Asn Arg Ile Ala Glu Asp Ala 930 935 940 His Tyr Val Tyr Arg Tyr Asp Glu Tyr Gly Arg Leu Ala Glu Lys Thr 945 950 955 960 Asp Arg Ile Pro Glu Gly Val Ile Arg Met His Asp Glu Arg Thr His 965 970 975 His Tyr His Tyr Asp Ser Gln His Arg Leu Val Phe His Thr Arg Ile 980 985 990 Gln His Gly Glu Pro Gln Val Glu Ser Arg Tyr Leu Tyr Asp Pro Leu 995 1000 1005 Gly Arg Arg Thr Gly Lys Arg Val Trp Arg Arg Glu Arg Asp Leu Thr 1010 1015 1020 Gly Trp Met Ser Leu Ser Arg Lys Pro Glu Glu Thr Trp Tyr Gly Trp 1025 1030 1035 1040 Asp Gly Asp Arg Leu Thr Thr Val Gln Thr Gln Gln Thr Arg Ile Gln 1045 1050 1055 Thr Val Tyr Gln Pro Gly Ser Phe Thr Pro Leu Leu Arg Ile Glu Thr 1060 1065 1070 Glu Asn Gly Glu Gln Ala Lys Ala Arg His Arg Ser Leu Ala Glu Val 1075 1080 1085 Leu Gln Glu Asp Thr Gly Val Thr Leu Pro Ala Glu Leu Ala Val Met 1090 1095 1100 Leu Gly Arg Leu Glu Arg Glu Leu Arg Gln Gly Ser Val Ser Glu Glu 1105 1110 1115 1120 Ser Gln Gln Trp Leu Ala Gln Cys Gly Leu Thr Ala Glu Gln Met Gly 1125 1130 1135 Ala Gln Leu Glu Ala Gly Tyr Ile Pro Glu Arg Lys Leu His Leu Tyr 1140 1145 1150 His Cys Asp Gln Arg Gly Leu Pro Leu Gly Leu Ile Ser Pro Gly Arg 1155 1160 1165 Glu Thr Ala Leu Thr Ala Glu Tyr Asp Glu Trp Gly Asn Leu Leu Ser 1170 1175 1180 Glu Thr Ser Ala Gln Pro Leu Gln Gln Ser Leu Arg Phe Pro Gly Gln 1185 1190 1195 1200 Gln Tyr Asp Glu Glu Ser Gly Leu Tyr Tyr Asn Arg Asn Arg Tyr Tyr 1205 1210 1215 Asp Pro Leu Gln Gly Arg Tyr Ile Thr Gln Asp Pro Ile Gly Leu Glu 1220 1225 1230 Gly Gly Trp Asn Leu Tyr Gln Tyr Pro Leu Asn Pro Ile Glu His Ile 1235 1240 1245 Asp Pro Leu Gly Leu Ala Leu Asp Leu Asn Tyr Tyr Ser Pro Ser Asp 1250 1255 1260 Pro Ile Tyr Lys Gly Ser Leu Asn Val Arg Glu Phe Pro Thr Gly Phe 1265 1270 1275 1280 Thr Val Gly Gly His Gly Ser Pro Thr Ser Met Ser Asp Asp Arg Ile 1285 1290 1295 Lys Lys Gly Ser Asp Leu Thr Ile Lys Gln Leu Ala Ser Asp Ile Arg 1300 1305 1310 Ala Asn Pro Lys Tyr His Glu Gly Met Pro Val Val Leu Phe Ser Cys 1315 1320 1325 Glu Thr Gly Lys Gly Lys Asn Ser Phe Ala Gln Lys Leu Ala Asn Glu 1330 1335 1340 Leu Asp Ala Thr Val Ile Ala Pro Asp Glu Ile Ile Trp Ile Trp Pro 1345 1350 1355 1360 Asp Gly Asn Tyr Ala Ile Met Gly Gln Thr Ala Arg Ile Thr Ile Gly 1365 1370 1375 Gly Lys Asp Asn Gly Val Phe Glu Leu Val Pro Asp Glu Lys Gln Pro 1380 1385 1390 Gly Asp Phe His Lys Phe Thr Pro Thr Gly Ser Lys * 1395 1400 <210> 1005 <211> 204 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29744..30355) <400> 1005 Met Lys Val Phe Thr Phe Leu Leu Ile Ile Met Val Cys Leu Tyr Asn 1 5 10 15 Phe Gly Val Arg Ala Ala Met Asp Asn Ser Lys His Ser Asp Glu Ala 20 25 30 Glu Lys Leu Leu Ala Glu Leu Ser Ala Arg Lys Gly Glu Gly Glu Gly 35 40 45 Glu Gly Glu Gly Glu Gly Glu Gly Glu Gly Glu Gly Glu Pro Lys Ser 50 55 60 Thr Val Ser Val Phe Tyr Leu Gln Pro Glu Glu Val Asn Thr Leu Ser 65 70 75 80 His Gln Ala Lys Arg Gly Asp Gly Glu Ala Gly Phe Arg Leu Phe Leu 85 90 95 Tyr Tyr Lys Leu Ser Asn Tyr Asp Glu Glu Lys Ser Ser Gln Trp Leu 100 105 110 Lys Ile Ala Ala Asn Asn Gly His Ala Thr Ala Gln Tyr Arg Leu Tyr 115 120 125 Val Glu Leu Gln Glu Gln Gly Glu Thr Lys Glu Ala Asn Glu Trp Leu 130 135 140 Gln Lys Ile Lys Leu Ala Ala Ser Asn Asn Asp Ser Ser Ala Ile Trp 145 150 155 160 Phe Leu Val Asn Cys Tyr Lys Asn Gln Gly Asn Lys Lys Glu Ala Leu 165 170 175 Gln Trp Ala Tyr Lys Leu Lys Ala Ser Lys Gln Pro Leu Asp Ala Asp 180 185 190 Arg Leu Ile Glu Glu Leu Thr Lys Glu Gln Lys * 195 200 <210> 1006 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30377..30559) <400> 1006 Met Glu Ser Arg Lys Thr Leu Pro Val Ala Thr Thr Pro Thr His Lys 1 5 10 15 Ile Thr Phe Thr Thr Thr Ala Thr Ser Ser Ser Lys Arg Lys Leu Lys 20 25 30 Pro Lys Leu Ala Ser Ser Ser Pro Val Ile Ile Thr Met Tyr Leu Ala 35 40 45 Asp Ala Ser Lys Val Ala Arg Glu Lys Met Lys Ile * 50 55 60 <210> 1007 <211> 97 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30703..30993) <400> 1007 Met Lys Ile Ile Arg Leu Leu Leu Leu Ala Cys Ser Ile Thr Ile His 1 5 10 15 Phe Phe Ile Val Lys Glu His Val Phe Lys Ile Phe Asn Gln His Ala 20 25 30 Tyr Cys Phe Leu Phe Ala Phe Tyr Val Leu Ile Val Phe Cys Phe Leu 35 40 45 Leu Phe Phe Lys Arg Ser Phe Ile Val Asp Leu Ile Ala Cys Ile Ile 50 55 60 Ile Pro Tyr Ile Ser Ser Val Ile Ser Phe Leu Phe Leu Ser Met Leu 65 70 75 80 Ile Ser Pro His Leu Arg Glu Arg Ser Pro Asn Ala Ala Phe Leu Tyr 85 90 95 <210> 1008 <211> 379 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(31101..32237) <400> 1008 Met Glu Leu Lys Lys Leu Met Glu His Ile Ser Ile Ile Pro Asp Tyr 1 5 10 15 Arg Gln Ala Trp Lys Val Glu His Lys Leu Ser Asp Ile Leu Leu Leu 20 25 30 Thr Ile Cys Ala Val Ile Ser Gly Ala Glu Gly Trp Glu Asp Ile Glu 35 40 45 Asp Phe Gly Glu Thr His Leu Asp Phe Leu Arg Gln Tyr Gly Asp Phe 50 55 60 Glu Asn Ala Ile Pro Val His Asp Thr Ile Ala Arg Val Val Ser Cys 65 70 75 80 Ile Ser Pro Ala Lys Phe His Glu Cys Phe Ile Asn Trp Met Arg Asp 85 90 95 Cys His Ser Ser Asp Asp Lys Asp Val Ile Ala Ile Asp Gly Lys Thr 100 105 110 Leu Arg His Ser Tyr Asp Lys Ser Arg Arg Arg Gly Ala Ile His Val 115 120 125 Ile Ser Ala Phe Ser Thr Met His Ser Leu Val Ile Gly Gln Ile Lys 130 135 140 Thr Asp Glu Lys Ser Asn Glu Ile Thr Ala Pro Pro Glu Leu Leu Asn 145 150 155 160 Ile Leu Asp Ile Lys Gly Lys Ile Ile Thr Thr Asp Ala Met Gly Cys 165 170 175 Gln Lys Asp Ile Ala Glu Lys Ile Gln Lys Gln Gly Gly Asp Tyr Leu 180 185 190 Phe Ala Val Lys Gly Asn Gln Gly Arg Leu Asn Lys Ala Phe Glu Glu 195 200 205 Lys Phe Pro Leu Lys Glu Leu Asn Asn Pro Glu His Asp Ser Tyr Ala 210 215 220 Ile Ser Glu Lys Ser His Gly Arg Glu Glu Ile Arg Leu His Ile Val 225 230 235 240 Cys Glu Val Pro Asp Glu Leu Ile Asp Phe Thr Phe Glu Trp Lys Gly 245 250 255 Leu Lys Lys Leu Cys Val Ala Val Ser Phe Arg Ser Ile Ile Ala Glu 260 265 270 Gln Lys Lys Glu Pro Lys Met Thr Val Arg Tyr Tyr Ile Ser Ser Ala 275 280 285 Asp Leu Thr Ala Gly Lys Phe Ala Thr Ala Ile Arg Asn His Trp His 290 295 300 Val Glu Asn Lys Leu His Trp Arg Leu Asp Val Val Met Asn Glu Asp 305 310 315 320 Asp Cys Lys Ile Arg Arg Gly Asn Ala Ala Glu Leu Phe Ser Gly Ile 325 330 335 Arg His Ile Ala Ile Asn Ile Leu Thr Asn Asp Lys Val Phe Lys Ala 340 345 350 Gly Leu Arg Arg Lys Met Arg Lys Ala Ala Met Asp Arg Asn Tyr Leu 355 360 365 Ala Ser Val Leu Ala Gly Ser Gly Leu Ser * 370 375 <210> 1009 <211> 587 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(32240..34000) <400> 1009 Leu Pro Trp Leu His Arg Glu Thr Ala Arg Ser Phe Gly Gly Ala Gly 1 5 10 15 Ser Thr Ala Gly Tyr Glu Gln Val Thr Ala Tyr Thr Leu Thr Gly Gln 20 25 30 Leu Gln Ser Arg His Leu Asn Leu Pro Gln Leu Asp Cys Asp Tyr Asp 35 40 45 Trp Asn Asp Asn Gly Gln Leu Ile Arg Ile Ser Gly Pro Gln Glu Ser 50 55 60 Arg Glu Tyr Arg Tyr Ser Asp Thr Gly Arg Leu Thr Gly Val His Thr 65 70 75 80 Thr Ala Ala Asn Leu Asp Ile Asp Ile Pro Tyr Ala Thr Asp Pro Ala 85 90 95 Gly Asn Arg Leu Pro Asp Pro Glu Leu His Pro Asp Ser Thr Leu Thr 100 105 110 Ala Trp Pro Asp Asn Arg Ile Ala Glu Asp Ala His Tyr Val Tyr Arg 115 120 125 Tyr Asp Glu Tyr Gly Arg Leu Thr Glu Lys Thr Asp Arg Ile Pro Glu 130 135 140 Gly Val Ile Arg Met His Asp Glu Arg Thr His His Tyr His Tyr Asp 145 150 155 160 Asn Gln His Arg Leu Val Phe Tyr Thr Arg Ile Gln Tyr Gly Glu Pro 165 170 175 Leu Val Glu Ser Arg Tyr Leu Tyr Asp Pro Leu Gly Arg Arg Thr Gly 180 185 190 Lys Arg Val Trp Arg Arg Glu Arg Asp Leu Thr Gly Trp Met Ser Leu 195 200 205 Ser Arg Lys Pro Glu Val Thr Trp Tyr Gly Trp Asp Gly Asp Arg Leu 210 215 220 Thr Thr Val Gln Thr Gly Thr Thr Arg Ile Gln Thr Val Tyr Arg Pro 225 230 235 240 Gly Ser Phe Thr Pro Leu Ile Arg Ile Glu Thr Glu Asn Gly Glu Arg 245 250 255 Glu Lys Ala Gln Arg Arg Ser Leu Ala Glu Lys Leu Gln Gln Glu Gly 260 265 270 Ser Glu Asp Gly His Gly Val Val Phe Pro Ala Glu Leu Val Arg Met 275 280 285 Leu Asp Arg Leu Glu Glu Glu Ile Arg Ala Asp Arg Val Ser Ser Glu 290 295 300 Ser Arg Ala Trp Leu Ala Gln Cys Gly Leu Thr Val Glu Gln Leu Glu 305 310 315 320 Lys Gln Val Glu Pro Glu Tyr Thr Pro Ala Arg Thr Leu His Leu Tyr 325 330 335 His Cys Asp His Arg Gly Leu Pro Leu Ala Leu Ile Ser Glu Asp Gly 340 345 350 Asn Thr Ala Trp Ser Ala Glu Tyr Asp Glu Trp Gly Asn Gln Leu Asn 355 360 365 Glu Glu Asn Pro His His Leu His Gln Pro Tyr Arg Leu Pro Gly Gln 370 375 380 Gln His Asp Glu Glu Ser Gly Leu Tyr Tyr Asn Arg His Arg Tyr Tyr 385 390 395 400 Asp Pro Leu Gln Gly Arg Tyr Ile Thr Pro Asp Pro Ile Gly Leu Arg 405 410 415 Gly Gly Trp Asn Met Tyr Gln Tyr Pro Leu Asn Pro Ile Gln Val Ile 420 425 430 Asp Pro Met Gly Leu Asp Ala Ile Glu Asn Met Thr Ser Gly Gly Leu 435 440 445 Ile Tyr Ala Val Ser Gly Val Pro Gly Leu Ile Val Ala Asn Ser Ile 450 455 460 Thr Asn Ser Ala Tyr Gln Phe Gly Tyr Asp Met Asp Ala Ile Val Gly 465 470 475 480 Gly Ala His Asn Gly Ala Ala Asp Ala Met Arg Tyr Cys Tyr Leu Met 485 490 495 Cys Arg Met Thr Lys Thr Phe Gly Ser Thr Ile Ala Asp Val Ile Gly 500 505 510 Lys Asn His Glu Ala Ala Gly Asp Arg Gln Gly Gln Pro Ala Lys Glu 515 520 525 Arg Ile Met Asp Leu Lys Asn Asn Thr Val Gly Ile Ala Cys Gly Asp 530 535 540 Phe Ser Ala Lys Cys Ser Asp Ala Cys Ile Glu Lys Tyr Asn Ile Gly 545 550 555 560 Gln Leu Phe Gly Leu Asp Gly Ile Lys Ala Asp Asn Pro Ile Lys Ala 565 570 575 Lys Gln Gly Ser Ser Asp Ala Ser Asn Tyr * 580 585 <210> 1010 <211> 57 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33984..34154) <400> 1010 Met Leu Gln Ile Ile Arg Gly Lys Leu Val Ile Phe Leu Ile Thr Leu 1 5 10 15 Cys Leu Phe Val Val Tyr Leu Gly Phe Asp Asn Asn Ser Asn Ser Asp 20 25 30 Ile Val Phe Tyr Gly His Lys Thr Pro Lys Ser Val Glu Ile Tyr Leu 35 40 45 Ser Glu Lys Ile Leu Phe Ile Lys * 50 55 <210> 1011 <211> 88 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34202..34465) <400> 1011 Met Val Asn Asn Tyr Lys Thr His Cys Gly Val Val Asp Ile Asn Leu 1 5 10 15 Asn Phe Phe Asn Asp Ile Leu Tyr Ser Val Arg Leu Lys Asn Ile Ser 20 25 30 Lys Leu Glu Asn Met Glu Phe Cys Ala Thr Lys Gln Arg Val Tyr Phe 35 40 45 Ser Asp Lys Asn Lys Lys Ala Ser Tyr Lys Ile Ile Asn Tyr Gly Asp 50 55 60 Tyr Tyr Asp Val Asp Tyr Tyr Asp Asn Asn Leu Lys Asn Glu Val Phe 65 70 75 80 Asp Trp Ile Gly Lys Trp Ser * 85 <210> 1012 <211> 391 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(34646..35818) <400> 1012 Val Ser Ile Gln Ser Leu Leu Asp Tyr Ile Ser Val Ile Pro Asp Ile 1 5 10 15 Arg Gln Gln Gly Lys Val Lys His Lys Leu Ser Asp Ile Leu Phe Leu 20 25 30 Thr Val Cys Ala Val Ile Ala Gly Ala Asp Glu Trp Gln Glu Ile Glu 35 40 45 Asp Phe Gly His Glu Arg Leu Glu Trp Leu Lys Lys Tyr Gly Asp Phe 50 55 60 Asp Asn Gly Ile Pro Val Asp Asp Thr Ile Ala Arg Val Val Ser Asn 65 70 75 80 Ile Asp Ser Leu Ala Phe Glu Lys Ile Phe Ile Glu Trp Met Gln Glu 85 90 95 Cys His Glu Ile Thr Asp Gly Glu Ile Ile Ala Ile Asp Gly Lys Thr 100 105 110 Ile Arg Gly Ser Phe Asp Lys Gly Lys Arg Lys Gly Ala Ile His Met 115 120 125 Val Ser Ala Phe Ser Asn Glu Asn Gly Val Val Leu Gly Gln Val Lys 130 135 140 Thr Glu Ala Lys Ser Asn Glu Ile Thr Ala Ile Pro Glu Leu Leu Asn 145 150 155 160 Leu Leu Asp Leu Lys Lys Asn Leu Ile Thr Ile Asp Ala Met Gly Cys 165 170 175 Gln Lys Asp Ile Ala Ser Lys Ile Lys Asp Lys Lys Ala Asp Tyr Leu 180 185 190 Leu Ala Val Lys Gly Asn Gln Gly Lys Leu His His Ala Phe Glu Glu 195 200 205 Lys Phe Pro Val Asn Val Phe Ser Asn Tyr Lys Gly Asp Ser Phe Ser 210 215 220 Thr Gln Glu Ile Ser His Gly Arg Lys Glu Thr Arg Leu His Ile Val 225 230 235 240 Ser Asn Val Thr Pro Glu Phe Cys Asp Phe Glu Phe Glu Trp Lys Gly 245 250 255 Leu Lys Lys Leu Cys Val Ala Leu Ser Phe Arg Gln Lys Lys Glu Asp 260 265 270 Lys Ser Ala Glu Gly Val Ser Ile Arg Tyr Tyr Ile Ser Ser Lys Asp 275 280 285 Met Asp Ala Lys Glu Phe Ala His Ala Ile Arg Ala His Trp Leu Ile 290 295 300 Glu His Ser Leu His Trp Val Leu Asp Val Lys Met Asn Glu Asp Ala 305 310 315 320 Ser Arg Ile Arg Arg Gly Asn Ala Ala Glu Ile Ile Ser Gly Ile Lys 325 330 335 Lys Met Ala Leu Asn Leu Leu Arg Asp Cys Lys Asp Ile Lys Gly Gly 340 345 350 Val Lys Arg Lys Arg Lys Lys Val Ala Leu Asn Thr Cys Tyr Ile Glu 355 360 365 Glu Val Leu Ala Ser Cys Ser Glu Leu Gly Phe Arg Thr Asp Lys Met 370 375 380 Lys Asn Leu Thr Gln Ile * 385 390 <210> 1013 <211> 34148 <212> DNA <213> Escherichia coli O157:H7 <400> 1013 cgccacgcaa ggcttttcca gcttttctcc tcaactgaag tcaacctgaa ccaacccaca 60 tcaacaggct tgtgagtata ctaatgagta tatttgccga ttcgatattg cttgtatact 120 cacgagatac caatggaagg aagaccatta tggccctaac ggatactaaa gttcgctctg 180 cgaaacctga ggagaaagag tattcacttg ttgacggcga cggcatgtcc ttacttgtaa 240 aacctggcgg ttcaaagtat tggcgatttc gtttccgttt tggcggtaaa caacatttga 300 tggcgttcgg cgtttacccg gatgtttcac tggcggatgc gcggaagaaa agggaagagg 360 ccagaaagct ggtagctgct ggtatcgatc ctcgtgagca taagcgtgct gtgaaagaag 420 agcaggcgaa agagattatt actttcgaga aggttgccag agagtggctc gtaaccaacc 480 aaaaatggtc ggaagatcat gctaatcgtg taaaaaagag cctggaggac aatatcttcc 540 cgacaattgg tactcgcaac attgctgaac taggcacccg tgatctgtta attcctatta 600 aagccgtgga gaaatccggg cgtcttgaag tggcttcccg ccttcaacag cgcaccacgg 660 ccatcatgcg ttatgcagtg caaagcgggt taattgatta cgatccggcg caagagatgt 720 cgggggcggt tgcttccagt aatcgacagc atcgtccggc gctggagtta aagcgtatcc 780 ctgagttgct tgacaaaata gacagctaca ccggcagacc gctaacccac tgtacgacag 840 aactcactct gcttatcttt attcggtcca gtaagctgca ttttgctcgc tggtcagaaa 900 tcgattttga aacgtcaatg tggaccatcc ctcttgattg gtattgcagt aagcagaggg 960 ttggactggt acagtaaata tcccgcataa tcgtgccatt cacatttaga gatcctccgg 1020 cataatcaat ctgccaatga aggagatcgc tattcgtaaa gcccctttta ctgagcatca 1080 gattatcgcc gtgattaaat cgcttgaata cgggcgaact gttaaagatg tggcttatct 1140 gaagccactt actacaactg caagtccaga tacggcggta tggaattttc tgatattaaa 1200 ataatcaagg atcttgagga tgagaaccaa cgtttcaaat agatgtttgc tgatctcatt 1260 atttggtcgg gatttttaaa gatgtatgga actaaaacgg gtctattttc agagggattt 1320 aactgaagca gaaattaata aatcataatt tataggtggc tggtatttaa tattcctgca 1380 tcatatctct gatgcaggag cagagaatgg ctataaatta ttagtaaaca gaatgtctat 1440 ctctcaccca caaacccctc ataagggtaa tttttacgca cctgcggcaa cgcaatagtt 1500 ttcccgtcaa aatcccagaa taatctctca acgatccctc cgccgtttac cgcatccgag 1560 accagtaccc gcatattttc atccaggcca atcgatcctt tatcaaaggc tttatggtgt 1620 attgcgcaaa gcgccagacc attggggatt tcacaagggc cgccgtgctg tttccatttt 1680 atatgcgccg cttccagcgc gacggtggtg tcatcgtggc gcatattaaa gccacatatt 1740 gcgcactggt agttataagc gcgtaataca tttttgcgaa ataacgggtc gcgctgttta 1800 cgggtttgct ggagatcaaa acccagctcg tcagcgattt cttcctgaat actctcggtg 1860 aagtgcgctt cgagtatctg ttgcgccaga gtattgatga gttttttatt gccggttacc 1920 agggcgtagt gctgttcatc gaaaccgcct gcaacgtggt attcgttcag ttccttcact 1980 ggcggttgtc ggctgctccc tgctgttgag caacgctcgg cattgtgtaa ttgccagatt 2040 ccgtcgcctt gtaatcgcca gaacggcata tcaggtcggt actgtgaacg ctgtggccca 2100 aaacgttcca gtaaactgtg cagaggttcg tagatttccg tgccataatc gaaaaggcgc 2160 ggatgtccat tcaggtatcc cgctaatacg tatagcagta acaatggttt atgcggcgcg 2220 cgctgttcac ccttgtgcca gatttttatg ttggcaattg cctgctgtag cgatttactg 2280 gaagccattg atatcccagg cagtgaaata attgcaatca tgctcgcaaa ttttctgctg 2340 ttcaagcctg caagtgaaga tccattgctg tgttgaggga tcaaaagaca acaaaaactt 2400 attgaagaaa taatcttctg cttttttgtc gaaataatgg gcattgatct tgtctatagc 2460 tgctgaatct tttccagcct cgttgagatc ttcaaaatag ccattgaaga tgttctggtt 2520 aacaccgcca gtaacataag ccttgccgtt gtgtacaaaa gtcacattac ccgccatgcc 2580 catcggcgcg tgcgacatca atttattgct ttattcattg tgactgtctt ctgtctacca 2640 agctttaacc ttcacccata tgagggaagt tttaagtatg aggcgaacca tagcatatgc 2700 ttttatacct gttacaccat aaaaatcaga caagttatgc cataaactac ttttgtaatt 2760 tgagccacaa atcagggaaa ttttatttat cttccgtgaa agtcttaact ttcacggagt 2820 tttagaattt acaattttgc tggcgtaaag gctcctgttt gtatttcttt aaccagctca 2880 cccacggtat atattctcca tccttcgact tcggcgggag taaggttaac tgcaatttta 2940 aggcctggcc atgcagcttc tacggttgca ataatttcat gttctgagtt tggaagatct 3000 aacccaggaa caggaggttg aaagccttta tgttgcatca tattaatatc accatgcact 3060 gatggatcag tcaggtcata tatttcattc caggattctg cttttaataa cccttgttgg 3120 gaacgtaaac gttgaatgat agccatctct gcttgggtaa cgaatatacc ttcgtggagg 3180 ggctgttttc gatggcaatc cttgcacaga acaagaaggt tttcatggtg attatcatat 3240 ttgatgccat ttttatgatg gacatggcac aagtttttgg cggttgataa attcacgcca 3300 caatcattac aaacataatt tgccttttct cgtatttctt tagatatttc cttccagttt 3360 tcgacatacc cactatttgt tttgtcatag atacccttag gcatatgacg aaaacaagta 3420 ctataatctg aaaaaaactc atttaatgag aatgatttaa aaatctctct ttttcgttgt 3480 ttatcaatac ttcctttata attaagtcgt tcgaggcaat tcatacatac ccgtaaatca 3540 acatcctggc tccgacctga accatcatca atttcgaata aaccatctat gcggttagtt 3600 gcatgatacc tttcaaatcg atttttatgg cgcatttcat caagagttct gcaccaggca 3660 atatgaaaac gttttccttt ttcgccatct acgatagccg catcataacg ccctgaatgg 3720 tcccgaatat ataaaagaac ctggcggcca tgataagaga taagcccgct accagggtca 3780 agatcttcga tactaacttc tttacccgtg gataactcaa tatctatagg atcaaagtca 3840 ataggggatt catccagaaa aaaatcgact ccttctggta acattttctt ccctaattga 3900 ataagttctg aaatgtcgat agataatttc atctcttact cctgaataat ctttctaatc 3960 tgcaactcgg catttgttac aactttgaag gtgacacgac gagagcgatt aggatcctcc 4020 ttgccggttt tatcaagaat gggatgtgca gatgaataac ctactgcggc aaatttactt 4080 ttaacccatt gttggtgtgt cgcgatattt tttatgtcat aaacgtattg taatactgca 4140 cgtgtacgac cttgcgatag tgccatatta ttaaaataag caatatcagg attcgttgtt 4200 cctgtccagt cagtacttgt gtgaccttca atgcggactt cagtaatatg ttcctgataa 4260 ttatctagaa cttttaggta gcgaggaaag aagtcgtcaa gaatgagttt aaactttggt 4320 tttagctctg tgcttcctaa gccaaataaa acatccggtg atttaaatcg aacctccaga 4380 gtctgtttat cgatctctgc atcccagtct tgtaaatcct ttgcaaactc aatatccaga 4440 gcattataaa gctgtaactg agcattctcg taggctacgg caacttcttt aattttttct 4500 ttttcaatac gtacgtagtg catataagca atagatatga acataaaaac catcatcagc 4560 ccagccatta ggtccgacat ggatacccaa tgttcattat cttgatcttt tttaggtaat 4620 tgtttcccta taatcttatc catgatcgat tacccgcgat gtttattagc agaaattaat 4680 gcttgtaact gccccataac tatttggtaa tctttaataa gtttttcata gttaccgaca 4740 aaacctttgc tgattgaaag cagagcatta cctaatgatt gcatttcacg gttcatttca 4800 cgttcagttg cttgctcaaa agcatgtaac tgctcgttga tggatagagc aaatttttca 4860 attgattctc tgacttgaga agtcagccct gcacttgcct tatcaaatga tgtctggatt 4920 gaatcaaaca tattatcggc attactggat agttgatggt taatcttttc accagtctta 4980 ctgaacatat caatcacatt cgtcgtattt tgttccatat ttctatgcaa ttctttcgag 5040 tgcgactcta gtgatttcag gaattcttca ccactttgtt tcatttcagt aattgtttca 5100 cctaacgtgc tggttagggt ttcggaggaa ttgctgacat catgtgccat cgaggcaaat 5160 gcttgttgtg tttgggtaac cgattgtctg aatccttcgg taccttcatc cagggcaacg 5220 cgcattgaat ctgcattaag aagtatttgc tggctggttt gctcaagaga tgcactaaca 5280 tttgcagctc cggatttcag cagttcaccc acttcagcca ttttgttctg tatttcaggt 5340 aatacggttg tagctttatc gcggatggcg acaaaggttt ctaaatggcg ggagagttcg 5400 ctgatttgat gttggttcac ctgaagcact tcacgcagtt cagacatagc cagaggaatt 5460 tctttacatt cttcccaaat ccctgcaacc gcagtttttg tttcaaccag ggactcgaca 5520 ctttgttgat attgttctga catctgctca atttgcgttt tataatttcc ctgccactca 5580 acaagttttt ttacagaggc atcaagagct ttaaagtttt caccaaactg ttcagttaaa 5640 ttttgattaa aatcaataat gacttgtcgc aaagcatcaa taatttgttc tgtagcacct 5700 tttgccatta gatctgcaaa ttgttcaagt tgttcccaaa gcttattact gaaatgagtg 5760 tgattagcta attgtgcctg cgaggaatcg ctaatctcag tacgtagtaa ttttatttga 5820 gcaataagag aaccttcact atcaccgtta atacccgaga ctaatttagt cagagtctgg 5880 ttctgctctt ttaattcatg atagatatgt tcaggtgtaa cagattcagg gttattttct 5940 gctaacgcac ttcgtttatt ggcaaaaaag aaagcatcca ttccattaaa taaaatggca 6000 aaaaacatac ctacaatgct tgtaatgaat gctgttttta ggccacctaa taatacgggg 6060 atgctggtat caatactttc ggtattaaaa ttgagtaaac caataataat accaatgaaa 6120 gtacccagaa tacctaatgc ccccattaag gttggagcat attctctaaa cttactatgt 6180 atattttttt tgtcacacca ccacgctgat aaaaatacga atataacagc ccagatgaaa 6240 atattggtga tcagtgtaga gtctatcgat tgaaacaact gctcaaaaag ctgcgctaac 6300 attttgatac ctgtgtaaat aatggatagt tgtaatcgtt taaaaaataa acaaaacaca 6360 cataatttat atggttaagt tcggtgtagc gctcatgatt gtaacaagtt ttttcgagat 6420 ataaatgatt tgtctcattt ttagcgagtt catcgggttg agctttttta tgatgatagt 6480 aacctgttac gaattgtatc aaaggaaggc aggttgcttg tgaaaactcc agttaaccca 6540 cttttgcaat ggcttaacat gttttttagt cgccgttcat tatccggagc tgatggacgg 6600 gcgttatatg cttaccgttg tactgataca gagtacgaaa gtttggcaga actactgcgt 6660 acatatgccc cccgtagtta tccaagaacg atattcattt cctatagcga tgttctattt 6720 agcatatatg ccgcagagtt tatccgccgg actcatacgg tcggacaccc taaatgggac 6780 acaattttag attctattaa ctggaaagtt ccgtatgttc atcgacagaa gctggttaat 6840 gatggcattc gctactggaa aagaaagata agaaacctgg gacaagcttc gggttatctg 6900 catacactgg cttgtgaagg tggtttgcct atccgcatga ttgaaaatga gagcggttat 6960 ttgattacct atttcagaag gatatatcag gcgcttcgtg ggcaatcatc tcaatatcct 7020 gccgctaaaa ttgcacaaga attaggcgat acgattcctg tcacaatgca aaacgaactg 7080 gtctatgaaa tagccggtga attctgcgag actctctgcc gattacttag tgagcatcct 7140 cctcatagca gtgatcccgt ttctgcatta cgtaagctct ctccagactg gcatcttcaa 7200 cttccactcg ttctccccga agcgaatgct gcagagattg taaggcgatt actttctcaa 7260 tcttctgaaa tacgcagtgc aagtagtctt caggttgaaa gaatctgggt cgatgttgat 7320 gacagttggt attgcgatgc ccggttccga ttcccggcca caatgcgtac agaacagtta 7380 acctctttgt ttgaatgcca tattcagccg gagcagaccc gactcatcat ttcaggaaaa 7440 tggaaaaatg gcggggcaag gttggcaatg ctaagccgtt atgagcagca agattggcgg 7500 gtcgagttat tacctattgc gatgcaaaaa ctctctggtg cagatgcaat ggccgaaatc 7560 tcattgtcgc ttcatgaagg tccaattctg ttaggtcaca caattccaaa aggcggttat 7620 gaacttactg aagaacttcc ctgggttttt gaagcgatga atgagagtga atcgcagcta 7680 aaacttgttg gtatggggtc tgtgagttcc aggctaaatg ctctgtttat ttcgctaccg 7740 aaaaatagcc atttagatat tagtggagaa ggtgagtttg atatcccaag gttgctgaaa 7800 aacagtgaac gcagcttaac taaaataagt ggagtattta gcgttgtttt acatgatggt 7860 gctgtttgta caattcgcac ccagcaactt tatgattctg cgattgaata ttatattaaa 7920 tcgacagaag ttgaactggt taaatcggat tatcctgtcc atcgagcctg gccgaagatc 7980 ggttggaaaa aggatctgca atatggcatt gtaccggaga aagaactttt ttggcgttcc 8040 attcgttcag gtaataatgc ctggtattct gtcgcatcag aaatgccaaa aggacagata 8100 gaagtccggc gaatagttaa tgatgaggtt ttatttagcg gtaaagttgt agttttacca 8160 gcagacttcg atattaatat tatacctgag agtgctcagc aaggcattat tatgctttct 8220 ggtataacgg atactagaat tgataaatat tcaaacaatg aaaaagtaac acttaagtcc 8280 gattattcac aaaacgagtg tgctatttat tataattcat cgctgatgct ggaaaatacc 8340 gttgatttac gggtctcctg gaaagatggt tctaatctta aactattatt acctaagccg 8400 gttagcggtg gccgatttgt aactaatgat ggttctgttc attttgatgg tgtggcatct 8460 atagcacatt tgcatggaat agatgctgag ttattaacca tatcatgtgc tggaagagga 8520 tatcttaata tcgagttatt ggatgaaaat ccagtagctg aaaaattccg ctatttacat 8580 gccgaccttc ctcttttatc aggacgcaat gacaaattac aacaaatttc actttatgag 8640 aactataatt tgctaaatgc tatgctggca tgtgcatgga acagcaatag tacattatgt 8700 gttgattttt actctgacag atttggaaag gataaagcaa cactcaatat taaacgctac 8760 gatggtagtt ttattgaaca cgatcaaggg ttactggttg atataaaaaa ttctgttgtt 8820 tttcctgcaa atagaataga cgaactggtt gttgatgcta tttctcttaa gaatcctggc 8880 ttacacatat cattgttaaa aaaagatgag tttgcttatg atctttcagc tctgaatgtt 8940 caggatagtc catggttaat tgtgggaaaa cttgatggta cagctcgcat tgcaccagta 9000 attaaatgga tgctacctgt attgcagaca aatgatttat tactaaatgc tctatgcgaa 9060 gcagacccag aacagcgcaa aaaaaatttt aatgagctaa tttttgaaat agataacaac 9120 ccattgcaaa attattgctg tttattaaca gagtatatta agaaatacaa aatgaataat 9180 ggcttatcct tgctggatct ggacttgttc agaggtattt cgagtaatta ccgcgtggtt 9240 gttcaattgt taatatcatc atgtctttct ggtgatagcg atacgattta tgatatacag 9300 gaagaattac ccttttcatg gggatggatt cccgtttcaa tctggaaaga tgttttccaa 9360 aaatgttgga cttatctgga gaaacagatt aacgataaaa cattagcatt acatatattg 9420 caacccttta ttgcttttat gaaccatcgt gcacatatcg atcgtcggct ggctccgatt 9480 gcgaatatgt tacttacata tagtgagagc ctaccaaccg gttgtgatgt attgccaact 9540 gttagtcgtg agcagtttaa tgaagctaaa cagatgctat taaggaaccc cgacagcttt 9600 gggcgtatca gtatcttccc taaagaactt tggtctagtg ctattactcc agagttaaaa 9660 tctgttttta ataagctttg gattgaagat aaatatcact cacggcttga aaaacgtttt 9720 aatttgatgt tagtcgcagc gctgttaacc caaaaagata ataacctgat acatcaactg 9780 tctgcgcttt ttgaatttca ctatcagcaa gccccacagc aattaggggt aatctatcaa 9840 tattattttg aacaagcagg agtatgtcat tgatggacgt tcagcaactg cattatgcgc 9900 cacttctaaa tcagcttcat cagcgtgcgg tgaggtcggt ggtaagtcag ttggcattgc 9960 ggagcaagtc gttgactcat tatctggaat cacaatattt tcagcctccc ggtcaggagg 1002 0 ggtcactgct tgcagacccg gtattcgaaa gtacattcgg ctggatgcct gcggatgaaa 1008 0 caatggagga tttgcgggac aagctgatct ccagcccgct ggttgatgca ttgagcaaag 1014 0 cgccagtgcc atttcgtcat caacttactg cgtggcgaac gattctggaa gacaaaaaat 1020 0 ccttgttagt gagcagcggt acgggatccg ggaaaacaga atgctttatg gtaccggttc 1026 0 tggaagatct tattcgtcag caaaaatcga cccgccagtc actaacaggg acacaagcta 1032 0 ttttcttgta tccgttaaat gcattaatta acagccaaca ggagcggctt cgcgaatgga 1038 0 cgcgcggatt taaggggaaa atacgcttcg cgctatataa tggcgaaacc cggcatacca 1044 0 aatacgaaat tcaggaagat cagttgaaag tacctgaaca agctttgagt cgggaagcca 1050 0 tttatgaagc accaccttcc atcatggtga cgaataccac catgctggaa tatatgctga 1056 0 ttcgtcgtaa agatgcccca atcatcgaaa agtctcaggg gatgttaaag tatatcgtcc 1062 0 tggatgaagc ccatagttat attggttctc aggctgctga gttagcgctg cttttacgtc 1068 0 gtgttatgca ggctttcaat gttggacccg gcacagataa acctgtgcag attatcgcga 1074 0 cctctgccac tattggtgaa gactctcctg aaggtaataa ggagcttgct aaatttgtcg 1080 0 ctgatctcgc gggcgttaca gaacgtgatg tcaaagtggt tcgcggttat cgacaaatac 1086 0 cgcgggtatc ggagtcgctg attcgtcatg aataccccac atctttaact tctcttaaat 1092 0 ccctgagccc tcaggatctt taccaacagc tttgtcatta ccgtgtggcc cagcaattgc 1098 0 gtcaggcgtt aactcatccc ggacggcagg cagtacgttt gagtgagttg ctcaatgttg 1104 0 ccagaagaac ctggccagat attaatcacc gtgagctact gcaactcctc gatctaatgg 1110 0 caagatcgcg agaaggtgaa ctggctttta cgccattacg tatgcatggg tttatcagaa 1116 0 cactggcggg tctatgggca tgttcaaaca aacaatgctc acataaagca catgaattaa 1122 0 atcagagtga ctggccattt ggtcaggtat ggtttgagca gcgccaatat tgtgactgtg 1128 0 gagcgccggt atttgaagtt ttacgttgct ccgggtgtgg ttcagcttat ttgtctgcca 1134 0 aagaggagat gcgcggtgat ggaacgaact ggttggtagc gcaaccagcc gctgccgaag 1140 0 tggatgagtt tgctcttgat gtagatgttt attctgaaga tgaagacaac gacgaattag 1146 0 acaataactc tcaatttgat cgtctgattg cgagcgatgg tgaaaaatat atcatttcac 1152 0 tggaagaaac gacggcgggg aaaattgata gtgaagcgca aaagcactat gaaataaacc 1158 0 tgttaagacc ggaatctcga ggtgagggac gcaataactc ctttgcttgt gtttgctgtg 1164 0 gtgacactca acggaaaaat aatcctttat tccgtccgct tcggctcggc gcgccctttt 1170 0 ttttaaatga aattattcct actctgctgg agttttctcc attaccgcaa acaagagaag 1176 0 agcagttagg accgtttaat ggtcgacgct tgctcacctt tacggattcg cgtcagggta 1182 0 ccgctcgcat ttcagcccgc ttacagcagg atgccgataa agcgacgttg cgagctcttt 1188 0 gttaccagga gctggcaaat attacagagc cttcagcaaa actcagcccg gcacactgtg 1194 0 cactgttaga gaaagttatt agccagtttt ctgtcctccc tttaaaaaat tccatcgacg 1200 0 cgctgaaaaa agcgatggct gcgaatgagg agcttagccc gacggacatt caggcactta 1206 0 aaattattga gccgatggtg agttccttaa gcacggagca tgctgaagcg atgcaaatac 1212 0 ttcaggctaa ctctggcaat cagcagaaga aaaccatgtc atggcaaacg ctgtctgaac 1218 0 agctggttgg cagtgtggac cttgccgata gaatgagagg cagttttaaa gaattgtctg 1224 0 ggcttgatct tactaaacaa cagtttgcag atttttgttt atacagcgag tttggtcgcc 1230 0 gccctaaaaa tgcctggacc ctcgaaagtc tgggtctggt agccattcac tatccattca 1236 0 ttgataaagt tacaacctgc ccgcaggact ggaagacatt attacccgat cccgataagc 1242 0 aattagcgga atggcgtaat ttattgaaga ttactcttga tttctttatc cgtgaaaaca 1248 0 gtgccgtttt ttacgaaaac gagcaatacc ctcgctggat gggggcacgt ttcccggtaa 1254 0 aaatgctcca ggggccagat aaaaaaaaca aagggcagaa acgtgatcaa ctttggccac 1260 0 aaatacgcga tcgccattat aaccgggtca ttaagctatt aatcgcagtc tttccggcaa 1266 0 tacaacctga gcaggctcac tggaaatcgt tagttaacca cttaatgatt gaggtctggg 1272 0 atgcaattcg accctgctta cgtcagtttg agtcgggtta tcagctggat attaaacaac 1278 0 aagctgaatt ttacagtcca aagcaagtgt ggcgttgccc ctatactcga cgtgcgttag 1284 0 acgtcacgtt gctgggatac tctccgtatt tgccgggtag caaagaaatt gcacctgaaa 1290 0 aagcagtgtt gattgaaatg cctgagcttc ctgtacgtca ctggcgtttg tctggtggtg 1296 0 gagaaatcgc ccgagaagaa cgtctggagt ggctggaaag taatgcgctg attcaacatg 1302 0 cccgcgagga aggattatgg tctactcgca gcgaccgact ggccctgaaa gatagctggt 1308 0 atcgtctgga ggaacactct gcgcagagaa cgcctgagca gaaccagttt aatgaaaaac 1314 0 aatttaagtc aggcaaagtt aatgtgctga actgttccac gaccatggag atgggggtgg 1320 0 atattggtgg tatgagtttg gtggcaatga acaacgttcc tccagcgccg gcaaattatt 1326 0 tgcaacgtgc aggtcgcgcg gggcgtcgtg gagagagtgc atctgctgcc attacgttat 1332 0 gtaaaaacac ggcgcatgga atggaggtat tcaaagaccc cctctgggcg ttcaacacta 1338 0 ctgccagtgc gccacgggtt cgttttggga gcagtagtat tgttcaacga catgttaatg 1344 0 ccctggtttt aggtctgttt ttacgagctg aagttcctga tgcgacaaaa ctgagttgca 1350 0 aatggttctt tgaaggtgat gagagccagt gtcttcgttt tctccattgg ttaaatcacc 1356 0 aggccgatca gctggcggat aaacttaaac gccttactca gggaaccgta ctgatgtcat 1362 0 tgacggcaac ccagctcttg acccgcacac aagcaatgat gcagcaggtt gatatccgct 1368 0 ggagaagcca acttgcgata ctgttggaaa atatcgaagc gttgaaggcg gataacagcg 1374 0 cgtgggaaga aacaccagca ggtaaagcca tcgcttatca gcttcgtgat tatcgcggtg 1380 0 catatctgtt ttctaaactc attagtgaag cgttcctgcc ggggcatggt ttcccggttg 1386 0 gcgtagtcaa tttcaattat ctgacggcag atgagctgga aaaacgtcgc gcaataaaag 1392 0 ccactcaggc tgaccctaat gaagggggag aaagcttttc tcgtcgtatt gaaaaattgc 1398 0 ccagccgtga tttgcctaca gcattacgcg agtatgcgcc tggtgcagat gtggtattgg 1404 0 gcggaaaagt atatcgttcc tcgggcatta tgcttggcaa ggtgcttgcc agcgggcagg 1410 0 agctgtcagg cgatcatcat attccgtggt tctggcattg ccgtaaatgt ggtgcggggg 1416 0 caaccagtac tacccatcct gtcgaatgta gtcactgcaa agcggatata cagcaacttg 1422 0 atgtgaagcg ttatttacag cctgttggtt ttgcgacaga tattcgttat caggcacata 1428 0 atgatgtatc catgcctgca caacttccct ggaaagatcc acgtgttctt gtaccgtctt 1434 0 cggtgtgggt ttctttaccc gatgctgggc taggacgtta ccgttttagc catagtgggg 1440 0 aattgttcca cttcagtgaa ggggaatttg ggcacggcta cgcaatttgc ctctcatgtg 1446 0 gtcgggcaga atctcaaact caaccccagc gtacccctga aaatctaaag aacccagaga 1452 0 gggaaaatac gcattacctg ttgcgagggg gcagtaacga tcgtcagggg agcaataaat 1458 0 tgtgccacgg tcatgtgcat aaagatctgt ggttgggata tagcagtcgt acagatatgg 1464 0 ttgagctgca actcaatgat gataatggcc tgttgatccg tgatgaggtt gccgcgcgtt 1470 0 cccttgcggt cgctttgcgt gaagggttag cgcataaatt gggtatcgaa aatactgagc 1476 0 tgggcgtgac gacgcagcaa gcgcgcgata tcaatggcta taccggatat tccatcttca 1482 0 tttacgacaa taatgcgggt ggtgcaggtt atgcagtgca attgatcgac cattgggctg 1488 0 atgtctttaa ttacgccaga aaattgctcg attgcagttg cgataaattc tgtcaccact 1494 0 gcttgctcag ctacgacagt cagcattatg tcaacagatt agatcgtcac catgcattaa 1500 0 ccctgcttac caatgtacgg ttgcagcgac ttaacctcgc gccagaatat cagtacttcg 1506 0 gcgatggtag ccgggttgaa actaaccctc tgagtttacg tattgcgcaa tgcctgaaca 1512 0 gcgagattta tgactcctgc tcgctggttc ttgcggggcc gcaggaacag tgggactttg 1518 0 cccaatggcc attatttaaa gagttgctcc agtttgcctc ctccggtggg aatgttgagt 1524 0 tgctggtggc cacgccgctg gcaaacttaa ctgatagctc cagacatcag ctttccgcgt 1530 0 tggcggcgat gccgggaggt cgcttacaag tgaaatccat tgccactgcg cagctcatgc 1536 0 aaggaaaggg gcgctggctt gcgcaggtga ctcgcgaagg gcaaagccaa cagtgggccg 1542 0 cagacgacag cgctaccgtt gcacctggtg aattatgggg acaaagtgcg tcttcaccag 1548 0 tagtgacact taaaggaacg tccggaaaaa ccttctcggg tcagacctta agtgcagaag 1554 0 atttactgcc cgccttaccc accggggcgg tgcgcatcaa tctctgtgaa caactggacg 1560 0 ggccgctgga aggttttggt tcgcgtttct ggtcgttagt cacgcaacag cacgctggct 1566 0 ggaagcaggc atttacccgc cacaaagaga taacgcatgt tgagtacagc gatcgttatc 1572 0 ttaatagccc attcacggcg cgtttgttag gtgaaatctt aaccgagctg gttgaacagg 1578 0 gaatggcgga acgcgccagc ctcactgttt gcgtcaaaaa attggattac aactctcgcc 1584 0 aacacgacgc tctctataac gcgtggctta atgaggaaga tcgtcagcag gttgtgacca 1590 0 ctttacttga agaaggatat ctggggcctg cgtggccggg agcaattagc tggttaacgg 1596 0 gggataacca gagtacggag catggacgag aactgacagt caccttcagc gatggcagtc 1602 0 agcattatgt cctgctcgac atggggctta gctactggcg ctgtattgaa gataccttct 1608 0 ttgattttgc cctgcgagta ccgcagcaag ttgaacggct ggcaaacacg cgagcgcgag 1614 0 ctgttgcccc gggtaatgac cttaggagtt atattatcgc tggataaata attgctcccc 1620 0 tggggatatc ttccagggga gttgacccag ctcacttttt aataattttt gtttgaaaat 1626 0 catgcgcaat ttatgcgcat tccctcccat tttgtcactt tgccgggggc cttcatgata 1632 0 tctttaaggc cctctttttt atcgcagtgt gccgcgccac atttttcagg atgacgttac 1638 0 cgccactgcc ccaaatagac agaaaaaccg atgaataagc aaaattatgc acctggtatg 1644 0 cgggtggtta ttcgtgatgc cgaatggcgt attcgccggg cggatgacag tggtgatggt 1650 0 gggtatttgc tgacctgcga tggtatttca gagcttgtgc gcggtaaaga agggttattt 1656 0 ctgaccaaac tggaacaaaa agtagagatc ctggatcccg caaaaacgca tttggtggaa 1662 0 gatgaatccg ccaattatca agcggcacag ttgtatattg aaagtcagtt acgccaacgc 1668 0 gtaccgacag acagtaaagt ccattttggt catctggcgg cgatggattc catgccgttt 1674 0 cagctcgatc ctacgcggat ggcgctggca caaccgcgtc agcggatact cattgccgac 1680 0 gctgttggtc tgggtaaaac gctggaagcc ggtattctgg tttcggaact gatccgtcgt 1686 0 gggcgcggaa aacgtattct ggttctggcg gttaaatcga tgctgacaca attccagaag 1692 0 gagttctgga gccgttttgc gatcccattg acccgcctgg attctgctgg tttacaaaag 1698 0 gtgcgtaacc gcatcccaac caaccacaac ccgttccact attttgacaa gaccattatc 1704 0 tccatcgata cgctgaaaca agacattgaa tatcgtcacc atctggaaaa tgcctggtgg 1710 0 gatattattg tcattgatga ggcccataac gtcgcagaac gtggaaccag ttcgttacgc 1716 0 agtaaactgg caaaactgct cgccgggcgc agcgatacgc tgattatgct ttcagcaaca 1722 0 ccgcatgatg gtaaggctga aagttttgcc agcctgatga acatgcttga cccgacggcg 1728 0 atcgccaacc cgaaagagta tgaatacgcc gattttgccg ataaaaatct ggttgtccgt 1734 0 cgcttcaaaa aagacgtgaa agatcagatg tccggcgagt tccccgagcg caatattgtc 1740 0 aaattgactc gcctggcatc cggtgccgaa gaagaagcat accgtcgtct ggttgagagc 1746 0 cagttccgtg atgatgacga tgaacaggcc cagtctaaca aaggtcgtct gttcaagata 1752 0 accctcgaaa aagcgctatt ttccagcccg atggcgtgtg ccagcgtcgt ggcgaatcgt 1758 0 ctgaagcgtc ttgagagccg taaagatcat aatagccaga gccagatcaa cgaactggag 1764 0 tcattgctgt tggcgctgaa taacattgat gccagccagt ttagcaaata ccagttgctg 1770 0 ctcgacacca tccgaaaaga cctcgcctgg aaagccaata acacggaaga tcgcctggtg 1776 0 atcttcaccg aaagtattaa aacgctggag ttcctcgaac agcaactgcg agcggatctg 1782 0 aaattgaaag atgaccagat cgccacgctg cgcggcgatc agggcgatac ggtattgatg 1788 0 gaaaccgtag aagcctttgg taaaacgcag tcgccgttgc gtcttctggt ttgttcggat 1794 0 gtggcatctg aagggatcaa cctgcatcac cttagccaca aaatgattca ctttgatatt 1800 0 ccgtggtcgt tgatggtatt ccagcaacgt aacgggcgta ttgaccgcta tgggcaaaaa 1806 0 catcagcccc aaatccgcta tctgcttacc gaggccagcg aaccacagat caatggcgat 1812 0 atgcgcgtac tggaagtgtt gatcaacaaa gacgaacagg cgcagaagaa cattggggac 1818 0 agttcggagt ttaccggcaa atttacccag gaagaggaag aagagcaggt tgcagagttc 1824 0 atgatgcagg atgatggtgc cagcctgttt gatcaactgc tgaacagcaa cgtctcggaa 1830 0 agcgccgaac acgatctgtt tggcgaaata tgcagtgcgg tttccagcga tgcctcaatg 1836 0 gtcaccgaaa cagacaccag cttgtttgcc agcgaacagg cgtactgcga aagagcattg 1842 0 ggttacctga aagccagtgg tcaaactatc cagtatgaaa ccttgcctga taataccttg 1848 0 tcgctggtgg caccggagga gttacgccgc cgcttcaacc agctaccgcc tgaaattgcc 1854 0 ccggagaact ggcagctcta tttaagtcag gataaaaccg tcatcaccga cgcgattgcg 1860 0 cgcgctcgcg gtgagcaaca tgcctggccc gatgtgcagt atctctggca aatcaacccg 1866 0 gtagtgcagt ggctggacga taaaatctct tcggcttttg gtcgtcatca ggctccggtt 1872 0 atccggctgc catacctgct tgaacccgat gaagatcact tcattctttc cgggttattc 1878 0 ccgaaccgta aatcacatcc gatggtgaac ccgtggatag tggtgagctt taaccgtgaa 1884 0 tcgctaatcg gcagtcagcc tttcgctgag tttttacaac gtcatccgca gttgagtaac 1890 0 aagctgacta acagcggcgg taaagatcgt aatcaccaac gccagcagga tttactggaa 1896 0 gcggctattg ctcatgcccg ggaggtattc atccatgatc ggaatgcgtt tgaaacgcac 1902 0 attaaccagc aactgaatga gcatctgcaa aagttggacg ttttgcgtgg gcggcagttg 1908 0 agccaacttg agctggattt tgccgataac aaacagcaat tgtcagtcaa gcagagccgt 1914 0 aaagagcaga gacaacgcga aatcgaacac aattttgaca gctatatcga atggattgag 1920 0 gacaccatga cgactgaaaa agaaccctac attcaggtaa ttgctgttat caccggagcg 1926 0 gagggttaat catggcgctg gtcggtatta ataacgaaaa cgaattttac tctaaccact 1932 0 atttgggtga ggttttcacc agtgatatcc gcgatgtgct ggaaccctgg atagcccagg 1938 0 aaaatgcagc gcgtgaagcg gagcgtgccg ctcgtgaaca gggcaaagac gtggagccgg 1944 0 gataccgcgc tccgtggaac cagtttaaca gtctggcgac tgagtttttc cgcaaacttg 1950 0 ccgagcacga aaaacagcgt cagatcccgc agcgtctggc cgatcaacgt aatcgctggc 1956 0 agccattgtt aaaggcgctg ggctacgaaa ttacgccaca gatccaaatg ctggatgacg 1962 0 atacaccgct gccggtactg gcgcgttaca acagcactga cggtagcccg tggctgtgga 1968 0 ttgttgaagc acacgatcag gaagaaggaa cgctggatcc gctggcgctc tccttactga 1974 0 ccgcgcaatt cccggcggat accgacaaac ataagcacga cagcctgcgc aaaaaagcca 1980 0 acggtgaata tcgcagctgg caggatttgc tctctacggc ggtcttcacc caaaatgaac 1986 0 cgccgcgttt tgtgctgctg ctcggtaacc gtcagctatt gttgttggac cgtactaagt 1992 0 gggcgcaaaa ccgtctgcta cgttttgatt ttgaagagat tttaagccgt cgtgaaacgg 1998 0 atacgctgaa agcgactgcg gtgttgttac ataaagattc tctgctgccg ggcagtgggg 2004 0 caccttatct tgactcgctg gatgacaatt cgcacaaaca tgcgtttggt gtttcggaag 2010 0 atctgaaata tgccctgcgc gaaagcattg agttgctggg caacgaagcg atgcattatc 2016 0 tgatcgaccg tggcctggca aactatacag gtaatcgtgc ggtggacccg gatgaactga 2022 0 gccgcgaatg tctgcgttac atgtaccgcc tgctgttcct gttctacatt gaagcgcgcc 2028 0 cggagctggg ttatgcgcca atgaccgcca aaacctatct gcaaggttac agcctggaaa 2034 0 cgttgcgcga tctggagatg atcccgctga ccagcgaaga agatcgcaac gggcgctact 2040 0 tccacgacag cctgaatatg ctgtttaaac tggtgcgcga aggctacaac ggcggcgtga 2046 0 aaatgcagag tgacctggag agcggcgacc ggatcaccat ccatagtcat cagttcagcg 2052 0 tcccgcgtct ggaaagtcat ctgtttgatg ccaacaacac gcgcattctt aaccgcgtgg 2058 0 tattccgtaa cgaaaccctg caacagatta tccaggcgat gtcgttaagc cgcccggcca 2064 0 aagggcgctt taaccgccgc ggacgtattt cttatcgcca gttgggtatc aaccagttgg 2070 0 gtgcggtgta tgaggcgctg ctctcctatc gcggattctt cgccagcgaa gatctctacg 2076 0 aggtgaagaa agccggggaa gagtttaacg agctggagac gggttacttc gtcagtaagg 2082 0 atgagattag caaataccac gaagacgaga aggtctacga gaaagacggc agtctgcgca 2088 0 ttcaccgcaa aggcagcttt atctaccgta tggccgggcg cgaccgtgag aaatctgcct 2094 0 cttattacac cccggaagtg ctgacccgct cactggttaa atatgccctg aaagaactgt 2100 0 ttaaggagca gattgatccc attagcgatc cgcacgccaa agctgatgcc atcttaaacc 2106 0 tcaccgtgtg cgaaccggcg atgggcagcg cggcgttcct taacgaagcc atcaaccagc 2112 0 tggcggaagc gtatctgttc cacaagcagc aggcggaagg tcgccgtatt ccgcaggatc 2118 0 gttacaccca ggagttacag cgggtgaaaa tgtacattgc cgacaacaac gttttcggcg 2124 0 tggacttaaa cccggtggcg gtggaactgg cggaagtgtc gctgtggctg aacgccatta 2130 0 gtggcgatgc gtttgtaccg tggtttggtt accagctgca ctgcggtaac tcgctggtgg 2136 0 gcgcgcgccg tcaggtgttc aacaagagcg aactgaccta caaaaaagcc aaagatccga 2142 0 gctggcttaa cagcgagccg gtcgaactgg cgatgaacac gccgcgtgaa gagacgcaga 2148 0 ttttccactt cctgctgccc gacggcggta tggctaacta cagcgataaa actgttaagc 2154 0 agcgttatcc ggatgacttc aaagcgctgg acagctggcg caaagagttt attaaaagct 2160 0 ttgccgggca tgagattgct gatgtgcagc gtatcagcga aaaggtggaa gcactgtgga 2166 0 acacctatcg ccagcaactt aaagcagaac gtctgaaaac cgccgacagc tacccggtgt 2172 0 ggccggcaga aaacagcgag cagacgcgtt cttcgctgag cagtaaagat gaaaccttta 2178 0 gcggtcgtct tgaagataac agcgcctacc agaagctgcg ttgggtaatg gactactggt 2184 0 gcgcgctgtg gttctggccg atcgacaaag ccgatgagct accggatcgc ggcacctggt 2190 0 tgtttgagat tgaaaccctg cttgacggga ttgtaatcac ggaaaaagtc actgaagttg 2196 0 cggagcacac caccggcgat ctgtttgccg aagaaggcct gctgcgagaa gagtcttcgc 2202 0 tgttttctgt tgctggtcgt ctgaaaaccg aggtgttgtt ccgtcatttg ccgcgtctgg 2208 0 cgattgtcga tgccctgaga aagcagcacc gtttcttcca ctgggatctg gagttctgcg 2214 0 acctgtttgc cgagcgcggc ggttttgacc tgatgctcgg aaacccgccg tggctgaaag 2220 0 tggaatggca ggaagcgggc gtgctgggtg attacgagcc ggaatttgtg ctgcgtaagc 2226 0 tgagcgcctc gaagctggca acgttgcgta ttgatacctt taaccagatc ccggcgctgg 2232 0 aagcggcctg gcgcagcgag tatgaaggct gtgaagggat gcaaaacttc ctgaatgcgc 2238 0 agcagaacta cccggtactg cgcggggtgc agaccaactt gtataaatgc tttctgccgc 2244 0 aggcctggcg attaggggcg cagaaaggcg tggcaggttt cctgcacccg gaagggattt 2250 0 atgatgaccc gaaaggcggg caattacgtg cggcggtata tccgaggctg agggcgcatt 2256 0 ttcagtttca gaatgagtta aatttgtttg ttgaagttga tcaccatgcg aagtttagca 2262 0 gcaatattta ttctgctagc cctagcacag tgggatttga acatatatct aatttgtatg 2268 0 ctccgcaaac tattgatgca tgttttgaac attctggcag tggggacatt cccggtctca 2274 0 aagacgagat tgagagcgag ggaaaattaa aagttgtatg gaacacatct ggccaccgtt 2280 0 ctcgattaat aagtatcgcc actcatgagc tagaattatt tgctcgtcta tatgacagcg 2286 0 aaggaacgcc agcctggcag gcacgtttgc cagccttaca tgctaaacaa cttgttgctg 2292 0 tactggaaaa gtttgctaat cagccgaata gattaggtga tttgcagggg cagtattttt 2298 0 caacggttat gttcgatgaa acatatgctc agagggatgg gacaatttta cggcagactc 2304 0 aattccctca agattcatca caatgggtac tgtctggccc tcatttcttt gttgggacgc 2310 0 cgttctacaa gactccgcgc gaaaactgta cgcttaacag cgattatgac tgcctggact 2316 0 tgctaactct gcctgacgac tatctgccgc gcactaacta cattccggca tgtgatgcac 2322 0 aggagtatgc aaaacgtact ccatgcgtta catggactga actggctgaa gatgaaccga 2328 0 agaaggtaac agattattat cgcttagcta tcagagccat gttggctcaa tcgggggaac 2334 0 gtacactaat tagtgctatt tatccgccag aaataagtca catgaacgca gtacgttctt 2340 0 actgctatag ctcacagaat ctgttactcg aacattcagg tatgtgtttt tctttacctt 2346 0 ttgattttat ttgtaaatct actggcaagg caaacttaca tcagatgctt gatggtttct 2352 0 catacgtatt attcaatccg agacaaaagg cattattata ctgcttagta ttatcattaa 2358 0 attctgtaaa tgatgtatat gctggccttt ggcaatcctg ctacacccca gacttcaaca 2364 0 cccagcgttg gagccgcgat ctcccgcagc tcccccagga tttcttcgcc aaactgaccc 2370 0 cagagtggca gcgtaactgc gctttacgct ctgactacag tcgtcgtcag gcgctggtgg 2376 0 aaatcgacgt attggtggcg caggcgctgg ggttaactct cgaagagctg cttaccattt 2382 0 atcgcgttca gttcccggtg atgcgccagt acgaagcgga tacctggtac gatcaaaacg 2388 0 gtcgcattat ctttacccca agcaaagggc tggtgggcgt tggcttgcct cgcaccgcgc 2394 0 gtaaagctga cctgaaaaac ggctttgtct ttaacgtcga cagcccggag tggaccggcg 2400 0 gtgactgcac cgatcaagct atcggttggg atgatgtcaa acatcttaaa accggtaccg 2406 0 tcagcgtcac ctttgatgat tatacccgca gcgacgaagg tgagcgccgt accgtcacct 2412 0 ggcaggctcc gtttatcaag ccagatcgcg aagatgacta caaagtggcc tgggcgttct 2418 0 ttgcacaaga taaggagagc gcctgatgtt gccgtccgtt gtcagtcggc aggtcgccga 2424 0 cagcgttgcc gcctttttac gggcggcgtt cccgctaaac agcccgctgt ttaacggtga 2430 0 gaataacgat aatgtctcaa tgctggagca atttctggcc cagccggaaa cgctgctgaa 2436 0 aggaccatac ctttccgccc agttgccgtt tcgtaaaagt gacttaccgc tgaatttttt 2442 0 ccctaatctg acgctgccgt tcccgccgca cgcgcatcag gcccgggcat ttcagcgtct 2448 0 gggaagcgac gcgccacagc cgacgctggt cgcaaccggt accggctccg gtaaaacaga 2454 0 atgttttatg ttcccgctgc tcaaccactg cgcgggcgcg tcacaagccg gggttaaagc 2460 0 gattatcatc tacccgatga acgccctggc aaccgatcag gccagccgtt tcgccaaaac 2466 0 catcgccagc gatccacaac tgcatggcaa ggtgaccgtc ggcctgtttg tcggcgacag 2472 0 cgaaatcgaa cccagcaaaa aaatgtcggc agaaaaggtc attacctgta agcacacgct 2478 0 gcgcgaaagc ccgccggaca tcctgttgac caactacaaa atgctcgact acctgctgat 2484 0 gcgccctggc gatcagccgc tctggcgtta caaccagccc ggttcattgc gttacctggt 2490 0 cgtggatgaa ttgcatacgt ttgatggcgc gcaagggtcg gatctggcct gtctggtgcg 2496 0 acgtttgaag catcacatag gtgtggataa ccaacgattc gcctgcgtcg ggacatcagc 2502 0 taccgtcggc gacgaactgg ggcaactgct cgattacgca aaaacaatct ttgaccagcc 2508 0 gtttaccgat gacgccgtta ttcgcgaaga tcgctacacg gcagcggagt acttgcagaa 2514 0 ttacgccatt gcgtacagtc agtatccggg gccggaggtc gcttcggccc tggacccgca 2520 0 gagttacgct accccggtag cgtatcttaa cgggcaaatc cctttgtggt tccccgacag 2526 0 cgacttgcaa ctcccggacg atctggagag cgacgacggg cgtgaaaagc gtattgcgct 2532 0 ggggtcactg ttacgccgcc acagcgtgat gcatgtctta ctccatgatc tgcaaggcgg 2538 0 gatcctctct gaacgagagt gtctggaaaa tctccaggtc atgctggcag aaagcgccga 2544 0 ccatgcccga cgcgtgctgc aaagcattct ggcactgatc gcgcaggcac gtctcgaagt 2550 0 accggaaacg gaacacgatc ggcaaaaacg tctccaggcg aagaaagcgc gtccggtgct 2556 0 gccgtttgtg caactgcgct cccagttgtg gcttcgtgag atgcgtcgtc tggtcgccag 2562 0 cgtggcgaaa acgccccgac tggtgtttgc cgatgatgtg gcggtggaag atcgcgaaca 2568 0 ctatttgccg gttatccact gccgtgactg ccacgcaact ggctgggcca gcctgcgtca 2574 0 tgggcaaagc gttcagttgg aaacagacct cgacggcatt tatcgccagt tctttgaaaa 2580 0 agggcgctcc atcgtccttg ctttcccgga taacaacgaa aaagcggtca gtggcgcaca 2586 0 ccagaaactg tgtcctacct gtctgaaact gaaccgacag tccagcgtcc agtgtggaca 2592 0 ttgcggtcat acggaactgt tgcaggtact gatcccggat atgctcaaag agcgtaagga 2598 0 cgagctggag tttgctaatg aatgcccgta ctgcaacagc aaacagggga tttcgattct 2604 0 ggggtcacgg gctgccagtc tgtcggcggt gatgattcac cagctttatg gcagccagtt 2610 0 caacgaacat aaaaagctga ttacgttttc tgactcggta caagacgccg cgcatcgtgc 2616 0 cagcttcttt actgcccgta cctggccgct gatgattcgt gggcaaatcg ccagtgttct 2622 0 tagcgaaaaa gagacattac cgctggatgc gttcgcggcg cgtgtttgcc aacaaacgcg 2628 0 tgaacgttca ccggacgatg ctcattttgc agcaaacgtc atcgcaccaa atatgcagtg 2634 0 gctgaatgat tatcagacgc tgaaaaatga aggcaaactg gcggagaact ccgatctgcc 2640 0 ggagctggtt tccctgcgcc tcgactggga ggtgtacagc gaatttaccc tgcgcgcgcg 2646 0 tatcggacgt acgctggaag ccaccggtta tgccgttgcc ggagtggata aagatcgctt 2652 0 caatccggca attaccgccc tgcatcaaca gctttgtgaa gagctgggtg atgagatgtc 2658 0 tggtgtgagc gtcgagcagg tagcgcacct ggcgctgggg gttatctggt atcaacgcca 2664 0 ggccggggcc gttatgcatc cggcgttcga aagttatcgc cgtgatggca cgacctttat 2670 0 gatgacgcaa aaagagcgta cctcgcgcta tatgccttct atcggtccga aaacgcgtaa 2676 0 accggcttat gcgtcgtttg aaaaaattaa tggtttccat cgcctgattg gcgcgaagtc 2682 0 taaccccagt tggtatcagc attggatcaa tcgcacgctg agtaacggca ataatctgtt 2688 0 tatcagtagc gttgcggaaa cagtgttacg acgcctgttt acggcgttga aaatagccgg 2694 0 agtagtaaaa gattttgaca ccaaagggcg tgaagcctgg ggactggtgc cttcggcgct 2700 0 ggtggtgagc cgtgacgtcg ttcagcttaa ttgctcatgt tgccgtgagg ttgtccgggc 2706 0 tccggccgat caaggctggc agtggcgtaa tgcgccttgt ctctctttac gttgtgaagg 2712 0 tcgttaccag gaagtcgaca atacggcgac ctggcgttgg gagaacatgg acatcgcgcg 2718 0 cgtacagggc gcagaacaca cggggctgct tagccgtgaa gatcgcgaag tcaccgaaaa 2724 0 atcgttctac cgcggcaacc aaccgtggaa tatcaacctg ttgtcggcaa caccgacgct 2730 0 ggagatgggt attgacgttg gggatctttc caccgtttta ctctgttctg tcccacctgc 2736 0 tcaggccaac tacttgcagc gtattggtcg cgccggtcgt aaagatggta acgcgttaaa 2742 0 cattaccgtg gcagaaggga acccgcacga tcagtttttc tttgaagaac cactggagat 2748 0 gatgcagggc caggtgcagg ctcctggcgt cttccttaat gcaacggcta ttctcgaacg 2754 0 ccagctggca gctttttgta tggataactg ggtgaaaacc ggtgtaccag aatccgctat 2760 0 ctgtaaaaac gtcaaacaga tgctggatga gctggagttc gggcgtaaat cgggttttcc 2766 0 gtataactta ctgcgatata tcgaacagca tcatgcggag attgctgcgc aatttacggc 2772 0 aatcttcccc gatcttgccg cagaaactcg ccaacagctg ttgtcttatc ttcagggcgc 2778 0 gccaggacaa cgctcgctgg tgcagcgtat cgaagaagcg ttaaaactgc tggtggaaga 2784 0 tcgcaaatct ttgcgctcac gcatcgataa actcaagcgc agtatcgata aactggagaa 2790 0 cgcgccgcgc gatcaaaact ttgatagcga tatgcgcgag ttaacttcgg aacggcaggc 2796 0 gctgatggcg ctggtcaatc aaatcaacaa taagcaaacg ctgaatttcc tcacggatga 2802 0 aggtctgctg cctaactacg ccttcccgga agccggtatt acgttacgtt ctgtgctctg 2808 0 gcggcgtaaa gaaggcgggg aagcacgtga atatcaaaac accactttcg aatatgaacg 2814 0 cccggcatca acggcgctgg ctgagctggc tccgctgaat aatttctatg ccggtgggca 2820 0 taaagttgaa attgagcaga tagacctgaa ggtctctgag ccggagaact ggcgtatctg 2826 0 tagccactgt aactacagcg aaaatatcga ccagacgggc gaccagcata aatattgccc 2832 0 gaaatgtggc acaccggggt gggccgatgc cggacaaaaa accacgctgc tgaaacttcg 2838 0 ccaggtttat gcccgcgcca gcgcacgtga tagccagatc agcgacgaga gcgacagccg 2844 0 tgaacctgct ttcttccagc gtcagctatt ggttagtttc gaaaaagaag atgtatcggc 2850 0 ggcatacgcg attgaggaag gcgaagttcc gtttggtttt gaatttttaa gcaaagtcac 2856 0 cctgcgggat atcaacttcg gcaaaatggc ggatgatgcc aatgagttga tgattgccgg 2862 0 agaagcgaag aagcgaaccg ggtttaaagt ttgcctcggg tgcggcatgg tgcagcgtcc 2868 0 tcgcgatcat gaaccacgtc atgatttgag ctgcaaatat cgcacggaac cggaaaaggc 2874 0 gaagttcgaa gattatctct acctctatcg ccagctggag tcagaagcgt tgcgtattct 2880 0 gctcccggta agcagttaca gtaatgaccg tgtcgtggag gcttctcttg gggcggcgat 2886 0 ccagctcggt cttaaacatt acttcaaggg gaatgtcgat cacctgaaag gcgttgtgta 2892 0 ccgcgagccg gaaaatgaag gcgaatcctg gcggcagtat ctggtgattt acgataccgt 2898 0 cccggggggg actggttctc ttaaagaact gatgcgcact cccgacaatt tgctgaaatt 2904 0 acttgaactg gcctatcagg caatagtgga atgcagttgc aacaatgata cgcataaaga 2910 0 tggttgttat cgttgcgttt acgcttaccg tgaccgtggg cgcatgaagt atgtctcccg 2916 0 cgatcaggcg cgtctcttgc tggcgaaaat tttgcaggca agagattcga tacgggtaat 2922 0 tgattccatc aaaaacattt ccctcgaagc catgatgggc agtgagctgg aaaaacggtt 2928 0 tattagctgc ctgcaagaaa ataaaaacct gattgtcagt cgcagttacg cgcatcaggg 2934 0 cgctgggtgg attattaaca cccgcagcga accgatgatg agctggcatc ttaaagctca 2940 0 ggtggattta ggcgctaaag aggcggtggg gatcccttgt cgcccggatt acgtgctata 2946 0 tccgcttatg cagtctgatg ccattaaacc ggtggctatt ttccttgatg gctttgcgtt 2952 0 ccacaaaaat agcgtcgcag aggatgtgca aaaacgccag gcgattcggg atagcggtaa 2958 0 tttctgggtg tggacagtca cgtgggccga tctcaaagag ccagggctta aacatgttca 2964 0 ggatgtcctg ggacttgggc ataacccgga tatgaaacag cctaagtttt ataacctgtt 2970 0 tcatgatacc aactttgcgg cccttgaagc gtcgttccgg gaacgcaaca gttttgcact 2976 0 gctgctggat tatctcgccg atccgggcgg aagaacgcag ttatggcaga gaatggctgc 2982 0 tgcacatgcc tgggtgtggt tggatgtgaa gaagtcacag gacgcgggaa cgaaacaaaa 2988 0 gtatgcctat gaaatgcagg aaaacgcgcc agcttggcgg ctagcagagc ttttgccaga 2994 0 cgaaccgttt gtctttggtg gtttactcga tagctgtaac tcatcgcagc aatttattga 3000 0 gctggcttcg gtgttaccac aacaagccat taaaccgacg accagcgtcg cacaaatgcg 3006 0 cagctggctg cgtttgcata tctgttttga cgatcgctat acgcaggatg acggttatga 3012 0 agcgggactc aatggcttct ggcgactggt aaacctgtta cagttcctgc cggatatgac 3018 0 ctttaccagc cgtaaagccg tgcatttacc gcaggaaagc gttgacacta aagtttcggc 3024 0 aacgccagag gcagtaccag agactgatga gagttgggct gagattattg agtttggctt 3030 0 attaagcgct gaagagatcg cgttgcttca gtctcattct ctctctgcgc cgactctcgg 3036 0 ctacgaattg caaaatgatg aaggtgaaat tattgcggaa gccgatctcg cctggccatc 3042 0 acaaaaatgg gcattgatta ttgataatca agaatttatt ccattattca caaccagggg 3048 0 ttggcacgtt gcattcgggc caattgacga aaatacattg caacatctgt ccggaggtga 3054 0 caaatgacgg tgcaaacgcc caaggtggca ctttctgatg gttttctggg cgcattcgcg 3060 0 cggatcccaa aggcacagca aaaaaaggtg caggaattca tctccaaatt ccgtcaggac 3066 0 ccgaccagta atggacttaa ctatgaaaag atccacgatg cgcgcagtaa aaatgtccat 3072 0 tcggtgcgaa tcgatcaaac ttatcgcggc attgttctga aacctgaaca gggtgccctg 3078 0 tatatgctga tgtgggtgga taaacacgac gaagcatatg actgggcgcg gcggcatgat 3084 0 tgttcaattc acccggttac cggcgcgatt caggtcattg atattagcta tatcaaaccg 3090 0 gcagcggaaa cagtggttga taaaccgaaa ctcttcgctg cttacagcgc ggaacagatt 3096 0 ctggctctgg gtgtgccgcc tgtctttatt gatcaggtga tggcgcttac cgatgaagcc 3102 0 gggcttaatc aacttgaaag cataatgcca gcagaagcct gggaacctct gcactggctg 3108 0 gcagaagggc tggattacca ggaagtgctg gaagagttta acgatcatcg tgatgagcct 3114 0 gttgatacca acgactttat ggaggcgatt gaacgaagta aacgtcgctt ccatgtcgtt 3120 0 gaaaatgaac aggagctgtt gcagatgctt aatgcgcctt tagaaaaatg gcgtgtattt 3126 0 ctgcatccga gccagcgaaa attggtggag tcgcccgcta atggtccggt acgagtactg 3132 0 ggcggtgcag gtacagggaa aacggttgtt gcgatgcacc gtgcgcggtg gttatctcag 3138 0 cgtctggcag ataaacccgg taagaaagta cttttcacga cctttacgcg taacctggcg 3144 0 gcagatattc gcgctaatct ccagcggttg tgtacgcgag aagagatggc gcgtattgac 3150 0 gtcgttaaca ttgatgcctg gatgagcgac caactaaaac gccacggtta tgatttccgc 3156 0 gtggtatacg acagcgatga agggcgacgc aaatgctgga actatgcctt gcagcaggca 3162 0 cctgccgaac tggggctacc tgataatttc tatgctgaag agtggcaacg cgttgtccag 3168 0 ccaaatgcgg tttacacccg ggaggaatac ctcaaagtca gccgggttgg acgtggtaca 3174 0 gcgttatccc gtattcaacg ggcgaaaatc tggccagtct ttgaagaatt cagagcacaa 3180 0 atggcgcgtg ccaaactgcg cgaaatgggc gatgccatgc atgaggctat tgttctgttt 3186 0 aaagaaaagc aggtccaact accttatagc agtattgtgg tcgatgaagc tcaagatatc 3192 0 ggtgccccgg catttactct tattcgcagc ctggttcccg agtcgcccaa cgatctgttt 3198 0 attgtcgggg atgggcatca gcgtatttat cgcaataagg tcgttcttgg tcagtgtggt 3204 0 attaacgtcc gtggtcgtcg cagtaaaaaa ttgaagatta actatcggac cacagaagag 3210 0 acgcgtcaat ttgctgttgg gctgttaact ggtgtgaagg ttgataacct cgatggcgaa 3216 0 gcggatacca gtaatgatta tttgtcatta ctgcacgggg aaaagcccat gattacgcat 3222 0 gcggcagatt tcaaagaaga ggctgcaacg ctcgtcaagc aaattcaggc attgctggcg 3228 0 aatcaggttc gttctcagga tatctgcatt actgcgcgta ctaaacatgc ttgtgaccgc 3234 0 tacgcatcag cactgaatga cgccggaatt gagacattta atttaggcaa tgatagcggt 3240 0 gacagcgatg cacgccctgg cgtgcgggtt gcaacgatgc accgtattaa agggcttgag 3246 0 ttccagtatg tgttcctggt ggggattaac gaaggcgttg tgccggaaat aaaagcatta 3252 0 gcatccgatg atcccgttga acagcgtgat gcattattta atgagcgcgc gttactgcat 3258 0 gtggctgcaa cccgtgccgt aaaagggctg tttgtttcat catctggtgt ccctagtccg 3264 0 ctattagtgg ctgactgata atatgtccaa aacaggccag gagccgaaac gctcctggtc 3270 0 tatataaccg ttctggcaac tggcgatatt tatattgctt agctcccaac agccagacaa 3276 0 tatcaactta gaaattatat tcgcttatgc ggtttgcata ttgcacagta caacctgttt 3282 0 tctctatatc taacgtaacg tcaggatgtg gatgattttt ggatggggtg acacactgga 3288 0 caaatatagc tggcacgaaa aggctggcat ttccagctga ccaatagtct ctggaaccat 3294 0 gatgatgata aaataaatat cttaagtttt aaacgtatga tgccaggatt accagaatta 3300 0 taaacgaata tattagttct tttctatttg ttcaggaggg gtataaaaat tgcaattgtt 3306 0 aatagtatcg tcaggacgat aaaaagataa tcatgacaaa ggcaattgaa ctaaaatgat 3312 0 tgacatttta caggtggttt gtcagtgatt tcttgttatt cataatttat tttccgtaaa 3318 0 aaatagtaag gtgatcacct gaataaaggt aatctcatat tttgatgagt atagtgattt 3324 0 tttatttctc tggtgaggaa tgaaggaaat atcaatggta aggaacgtca gagaatcagg 3330 0 gaaaattaag gtccctcaga aacacaatgc cgttcactta agcggggcgg cactgtgttt 3336 0 cacaggataa cgggtttttg atatcttaac cgccctcgcc cttgatggtc gggggcgttt 3342 0 tgttatgaac accacttcca gagcccccgc agatgctcca gtcgtttcgg gatagtcccc 3348 0 ggtgacgccg tgtttcccag cactatcatt tctgtcacga taaactggaa cgcgaactta 3354 0 aagctgatct ctgacgccgc ttttgttgcc tcacgccgta tcgctccgcc ggtaggcgcg 3360 0 gtcatggcat tcagtagaat gtgattccca gattcattaa cgccaccaga cgcatgacgg 3366 0 ggtaggcgct ctgccgctca gtggatgtgt tggcagagcc ataatattca cgcagctcgg 3372 0 gttcatcagg tgtcctgaac tgtgcgccat caatggcaaa aagttgcagg ccgtgccagt 3378 0 catccttcag gtaacgttcc gcgccccatg tctgtgtggt ctggcggaag agccattcca 3384 0 ccggggcggc ccccacgcgc tgacgcgcct gggtgacagc gctgcgggcg ccagcaggtt 3390 0 catccccgct tcgccatcca cgctcaggtt aagacgacga acggtcgcat gagcagaaag 3396 0 cgtcaggaag tgctgtatcc actcggtggg aaggtgctct gcaaacagtt gcgtagaggg 3402 0 tggtggcata agcggatggt cactgaaagt ggtataagaa aatggctcct tgttgtggaa 3408 0 gtcgttatag tgccgcacgc cggaggagtt aaaagcgctg atggatgcga ataaatcaaa 3414 0 ttaatgaa 3414 8 <210> 1014 <211> 276 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(150..977) <400> 1014 Met Ala Leu Thr Asp Thr Lys Val Arg Ser Ala Lys Pro Glu Glu Lys 1 5 10 15 Glu Tyr Ser Leu Val Asp Gly Asp Gly Met Ser Leu Leu Val Lys Pro 20 25 30 Gly Gly Ser Lys Tyr Trp Arg Phe Arg Phe Arg Phe Gly Gly Lys Gln 35 40 45 His Leu Met Ala Phe Gly Val Tyr Pro Asp Val Ser Leu Ala Asp Ala 50 55 60 Arg Lys Lys Arg Glu Glu Ala Arg Lys Leu Val Ala Ala Gly Ile Asp 65 70 75 80 Pro Arg Glu His Lys Arg Ala Val Lys Glu Glu Gln Ala Lys Glu Ile 85 90 95 Ile Thr Phe Glu Lys Val Ala Arg Glu Trp Leu Val Thr Asn Gln Lys 100 105 110 Trp Ser Glu Asp His Ala Asn Arg Val Lys Lys Ser Leu Glu Asp Asn 115 120 125 Ile Phe Pro Thr Ile Gly Thr Arg Asn Ile Ala Glu Leu Gly Thr Arg 130 135 140 Asp Leu Leu Ile Pro Ile Lys Ala Val Glu Lys Ser Gly Arg Leu Glu 145 150 155 160 Val Ala Ser Arg Leu Gln Gln Arg Thr Thr Ala Ile Met Arg Tyr Ala 165 170 175 Val Gln Ser Gly Leu Ile Asp Tyr Asp Pro Ala Gln Glu Met Ser Gly 180 185 190 Ala Val Ala Ser Ser Asn Arg Gln His Arg Pro Ala Leu Glu Leu Lys 195 200 205 Arg Ile Pro Glu Leu Leu Asp Lys Ile Asp Ser Tyr Thr Gly Arg Pro 210 215 220 Leu Thr His Cys Thr Thr Glu Leu Thr Leu Leu Ile Phe Ile Arg Ser 225 230 235 240 Ser Lys Leu His Phe Ala Arg Trp Ser Glu Ile Asp Phe Glu Thr Ser 245 250 255 Met Trp Thr Ile Pro Leu Asp Trp Tyr Cys Ser Lys Gln Arg Val Gly 260 265 270 Leu Val Gln * 275 <210> 1015 <211> 284 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1437..2288) <400> 1015 Met Ala Ser Ser Lys Ser Leu Gln Gln Ala Ile Ala Asn Ile Lys Ile 1 5 10 15 Trp His Lys Gly Glu Gln Arg Ala Pro His Lys Pro Leu Leu Leu Leu 20 25 30 Tyr Val Leu Ala Gly Tyr Leu Asn Gly His Pro Arg Leu Phe Asp Tyr 35 40 45 Gly Thr Glu Ile Tyr Glu Pro Leu His Ser Leu Leu Glu Arg Phe Gly 50 55 60 Pro Gln Arg Ser Gln Tyr Arg Pro Asp Met Pro Phe Trp Arg Leu Gln 65 70 75 80 Gly Asp Gly Ile Trp Gln Leu His Asn Ala Glu Arg Cys Ser Thr Ala 85 90 95 Gly Ser Ser Arg Gln Pro Pro Val Lys Glu Leu Asn Glu Tyr His Val 100 105 110 Ala Gly Gly Phe Asp Glu Gln His Tyr Ala Leu Val Thr Gly Asn Lys 115 120 125 Lys Leu Ile Asn Thr Leu Ala Gln Gln Ile Leu Glu Ala His Phe Thr 130 135 140 Glu Ser Ile Gln Glu Glu Ile Ala Asp Glu Leu Gly Phe Asp Leu Gln 145 150 155 160 Gln Thr Arg Lys Gln Arg Asp Pro Leu Phe Arg Lys Asn Val Leu Arg 165 170 175 Ala Tyr Asn Tyr Gln Cys Ala Ile Cys Gly Phe Asn Met Arg His Asp 180 185 190 Asp Thr Thr Val Ala Leu Glu Ala Ala His Ile Lys Trp Lys Gln His 195 200 205 Gly Gly Pro Cys Glu Ile Pro Asn Gly Leu Ala Leu Cys Ala Ile His 210 215 220 His Lys Ala Phe Asp Lys Gly Ser Ile Gly Leu Asp Glu Asn Met Arg 225 230 235 240 Val Leu Val Ser Asp Ala Val Asn Gly Gly Gly Ile Val Glu Arg Leu 245 250 255 Phe Trp Asp Phe Asp Gly Lys Thr Ile Ala Leu Pro Gln Val Arg Lys 260 265 270 Asn Tyr Pro Tyr Glu Gly Phe Val Gly Glu Arg * 275 280 <210> 1016 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2275..2601) <400> 1016 Leu Met Ser His Ala Pro Met Gly Met Ala Gly Asn Val Thr Phe Val 1 5 10 15 His Asn Gly Lys Ala Tyr Val Thr Gly Gly Val Asn Gln Asn Ile Phe 20 25 30 Asn Gly Tyr Phe Glu Asp Leu Asn Glu Ala Gly Lys Asp Ser Ala Ala 35 40 45 Ile Asp Lys Ile Asn Ala His Tyr Phe Asp Lys Lys Ala Glu Asp Tyr 50 55 60 Phe Phe Asn Lys Phe Leu Leu Ser Phe Asp Pro Ser Thr Gln Gln Trp 65 70 75 80 Ile Phe Thr Cys Arg Leu Glu Gln Gln Lys Ile Cys Glu His Asp Cys 85 90 95 Asn Tyr Phe Thr Ala Trp Asp Ile Asn Gly Phe Gln * 100 105 <210> 1017 <211> 368 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2829..3932) <400> 1017 Met Lys Leu Ser Ile Asp Ile Ser Glu Leu Ile Gln Leu Gly Lys Lys 1 5 10 15 Met Leu Pro Glu Gly Val Asp Phe Phe Leu Asp Glu Ser Pro Ile Asp 20 25 30 Phe Asp Pro Ile Asp Ile Glu Leu Ser Thr Gly Lys Glu Val Ser Ile 35 40 45 Glu Asp Leu Asp Pro Gly Ser Gly Leu Ile Ser Tyr His Gly Arg Gln 50 55 60 Val Leu Leu Tyr Ile Arg Asp His Ser Gly Arg Tyr Asp Ala Ala Ile 65 70 75 80 Val Asp Gly Glu Lys Gly Lys Arg Phe His Ile Ala Trp Cys Arg Thr 85 90 95 Leu Asp Glu Met Arg His Lys Asn Arg Phe Glu Arg Tyr His Ala Thr 100 105 110 Asn Arg Ile Asp Gly Leu Phe Glu Ile Asp Asp Gly Ser Gly Arg Ser 115 120 125 Gln Asp Val Asp Leu Arg Val Cys Met Asn Cys Leu Glu Arg Leu Asn 130 135 140 Tyr Lys Gly Ser Ile Asp Lys Gln Arg Lys Arg Glu Ile Phe Lys Ser 145 150 155 160 Phe Ser Leu Asn Glu Phe Phe Ser Asp Tyr Ser Thr Cys Phe Arg His 165 170 175 Met Pro Lys Gly Ile Tyr Asp Lys Thr Asn Ser Gly Tyr Val Glu Asn 180 185 190 Trp Lys Glu Ile Ser Lys Glu Ile Arg Glu Lys Ala Asn Tyr Val Cys 195 200 205 Asn Asp Cys Gly Val Asn Leu Ser Thr Ala Lys Asn Leu Cys His Val 210 215 220 His His Lys Asn Gly Ile Lys Tyr Asp Asn His His Glu Asn Leu Leu 225 230 235 240 Val Leu Cys Lys Asp Cys His Arg Lys Gln Pro Leu His Glu Gly Ile 245 250 255 Phe Val Thr Gln Ala Glu Met Ala Ile Ile Gln Arg Leu Arg Ser Gln 260 265 270 Gln Gly Leu Leu Lys Ala Glu Ser Trp Asn Glu Ile Tyr Asp Leu Thr 275 280 285 Asp Pro Ser Val His Gly Asp Ile Asn Met Met Gln His Lys Gly Phe 290 295 300 Gln Pro Pro Val Pro Gly Leu Asp Leu Pro Asn Ser Glu His Glu Ile 305 310 315 320 Ile Ala Thr Val Glu Ala Ala Trp Pro Gly Leu Lys Ile Ala Val Asn 325 330 335 Leu Thr Pro Ala Glu Val Glu Gly Trp Arg Ile Tyr Thr Val Gly Glu 340 345 350 Leu Val Lys Glu Ile Gln Thr Gly Ala Phe Thr Pro Ala Lys Leu * 355 360 365 <210> 1018 <211> 236 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3936..4643) <400> 1018 Met Asp Lys Ile Ile Gly Lys Gln Leu Pro Lys Lys Asp Gln Asp Asn 1 5 10 15 Glu His Trp Val Ser Met Ser Asp Leu Met Ala Gly Leu Met Met Val 20 25 30 Phe Met Phe Ile Ser Ile Ala Tyr Met His Tyr Val Arg Ile Glu Lys 35 40 45 Glu Lys Ile Lys Glu Val Ala Val Ala Tyr Glu Asn Ala Gln Leu Gln 50 55 60 Leu Tyr Asn Ala Leu Asp Ile Glu Phe Ala Lys Asp Leu Gln Asp Trp 65 70 75 80 Asp Ala Glu Ile Asp Lys Gln Thr Leu Glu Val Arg Phe Lys Ser Pro 85 90 95 Asp Val Leu Phe Gly Leu Gly Ser Thr Glu Leu Lys Pro Lys Phe Lys 100 105 110 Leu Ile Leu Asp Asp Phe Phe Pro Arg Tyr Leu Lys Val Leu Asp Asn 115 120 125 Tyr Gln Glu His Ile Thr Glu Val Arg Ile Glu Gly His Thr Ser Thr 130 135 140 Asp Trp Thr Gly Thr Thr Asn Pro Asp Ile Ala Tyr Phe Asn Asn Met 145 150 155 160 Ala Leu Ser Gln Gly Arg Thr Arg Ala Val Leu Gln Tyr Val Tyr Asp 165 170 175 Ile Lys Asn Ile Ala Thr His Gln Gln Trp Val Lys Ser Lys Phe Ala 180 185 190 Ala Val Gly Tyr Ser Ser Ala His Pro Ile Leu Asp Lys Thr Gly Lys 195 200 205 Glu Asp Pro Asn Arg Ser Arg Arg Val Thr Phe Lys Val Val Thr Asn 210 215 220 Ala Glu Leu Gln Ile Arg Lys Ile Ile Gln Glu * 225 230 235 <210> 1019 <211> 551 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4650..6302) <400> 1019 Met Leu Ala Gln Leu Phe Glu Gln Leu Phe Gln Ser Ile Asp Ser Thr 1 5 10 15 Leu Ile Thr Asn Ile Phe Ile Trp Ala Val Ile Phe Val Phe Leu Ser 20 25 30 Ala Trp Trp Cys Asp Lys Lys Asn Ile His Ser Lys Phe Arg Glu Tyr 35 40 45 Ala Pro Thr Leu Met Gly Ala Leu Gly Ile Leu Gly Thr Phe Ile Gly 50 55 60 Ile Ile Ile Gly Leu Leu Asn Phe Asn Thr Glu Ser Ile Asp Thr Ser 65 70 75 80 Ile Pro Val Leu Leu Gly Gly Leu Lys Thr Ala Phe Ile Thr Ser Ile 85 90 95 Val Gly Met Phe Phe Ala Ile Leu Phe Asn Gly Met Asp Ala Phe Phe 100 105 110 Phe Ala Asn Lys Arg Ser Ala Leu Ala Glu Asn Asn Pro Glu Ser Val 115 120 125 Thr Pro Glu His Ile Tyr His Glu Leu Lys Glu Gln Asn Gln Thr Leu 130 135 140 Thr Lys Leu Val Ser Gly Ile Asn Gly Asp Ser Glu Gly Ser Leu Ile 145 150 155 160 Ala Gln Ile Lys Leu Leu Arg Thr Glu Ile Ser Asp Ser Ser Gln Ala 165 170 175 Gln Leu Ala Asn His Thr His Phe Ser Asn Lys Leu Trp Glu Gln Leu 180 185 190 Glu Gln Phe Ala Asp Leu Met Ala Lys Gly Ala Thr Glu Gln Ile Ile 195 200 205 Asp Ala Leu Arg Gln Val Ile Ile Asp Phe Asn Gln Asn Leu Thr Glu 210 215 220 Gln Phe Gly Glu Asn Phe Lys Ala Leu Asp Ala Ser Val Lys Lys Leu 225 230 235 240 Val Glu Trp Gln Gly Asn Tyr Lys Thr Gln Ile Glu Gln Met Ser Glu 245 250 255 Gln Tyr Gln Gln Ser Val Glu Ser Leu Val Glu Thr Lys Thr Ala Val 260 265 270 Ala Gly Ile Trp Glu Glu Cys Lys Glu Ile Pro Leu Ala Met Ser Glu 275 280 285 Leu Arg Glu Val Leu Gln Val Asn Gln His Gln Ile Ser Glu Leu Ser 290 295 300 Arg His Leu Glu Thr Phe Val Ala Ile Arg Asp Lys Ala Thr Thr Val 305 310 315 320 Leu Pro Glu Ile Gln Asn Lys Met Ala Glu Val Gly Glu Leu Leu Lys 325 330 335 Ser Gly Ala Ala Asn Val Ser Ala Ser Leu Glu Gln Thr Ser Gln Gln 340 345 350 Ile Leu Leu Asn Ala Asp Ser Met Arg Val Ala Leu Asp Glu Gly Thr 355 360 365 Glu Gly Phe Arg Gln Ser Val Thr Gln Thr Gln Gln Ala Phe Ala Ser 370 375 380 Met Ala His Asp Val Ser Asn Ser Ser Glu Thr Leu Thr Ser Thr Leu 385 390 395 400 Gly Glu Thr Ile Thr Glu Met Lys Gln Ser Gly Glu Glu Phe Leu Lys 405 410 415 Ser Leu Glu Ser His Ser Lys Glu Leu His Arg Asn Met Glu Gln Asn 420 425 430 Thr Thr Asn Val Ile Asp Met Phe Ser Lys Thr Gly Glu Lys Ile Asn 435 440 445 His Gln Leu Ser Ser Asn Ala Asp Asn Met Phe Asp Ser Ile Gln Thr 450 455 460 Ser Phe Asp Lys Ala Ser Ala Gly Leu Thr Ser Gln Val Arg Glu Ser 465 470 475 480 Ile Glu Lys Phe Ala Leu Ser Ile Asn Glu Gln Leu His Ala Phe Glu 485 490 495 Gln Ala Thr Glu Arg Glu Met Asn Arg Glu Met Gln Ser Leu Gly Asn 500 505 510 Ala Leu Leu Ser Ile Ser Lys Gly Phe Val Gly Asn Tyr Glu Lys Leu 515 520 525 Ile Lys Asp Tyr Gln Ile Val Met Gly Gln Leu Gln Ala Leu Ile Ser 530 535 540 Ala Asn Lys His Arg Gly * 545 550 <210> 1020 <211> 1118 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6520..9873) <400> 1020 Val Lys Thr Pro Val Asn Pro Leu Leu Gln Trp Leu Asn Met Phe Phe 1 5 10 15 Ser Arg Arg Ser Leu Ser Gly Ala Asp Gly Arg Ala Leu Tyr Ala Tyr 20 25 30 Arg Cys Thr Asp Thr Glu Tyr Glu Ser Leu Ala Glu Leu Leu Arg Thr 35 40 45 Tyr Ala Pro Arg Ser Tyr Pro Arg Thr Ile Phe Ile Ser Tyr Ser Asp 50 55 60 Val Leu Phe Ser Ile Tyr Ala Ala Glu Phe Ile Arg Arg Thr His Thr 65 70 75 80 Val Gly His Pro Lys Trp Asp Thr Ile Leu Asp Ser Ile Asn Trp Lys 85 90 95 Val Pro Tyr Val His Arg Gln Lys Leu Val Asn Asp Gly Ile Arg Tyr 100 105 110 Trp Lys Arg Lys Ile Arg Asn Leu Gly Gln Ala Ser Gly Tyr Leu His 115 120 125 Thr Leu Ala Cys Glu Gly Gly Leu Pro Ile Arg Met Ile Glu Asn Glu 130 135 140 Ser Gly Tyr Leu Ile Thr Tyr Phe Arg Arg Ile Tyr Gln Ala Leu Arg 145 150 155 160 Gly Gln Ser Ser Gln Tyr Pro Ala Ala Lys Ile Ala Gln Glu Leu Gly 165 170 175 Asp Thr Ile Pro Val Thr Met Gln Asn Glu Leu Val Tyr Glu Ile Ala 180 185 190 Gly Glu Phe Cys Glu Thr Leu Cys Arg Leu Leu Ser Glu His Pro Pro 195 200 205 His Ser Ser Asp Pro Val Ser Ala Leu Arg Lys Leu Ser Pro Asp Trp 210 215 220 His Leu Gln Leu Pro Leu Val Leu Pro Glu Ala Asn Ala Ala Glu Ile 225 230 235 240 Val Arg Arg Leu Leu Ser Gln Ser Ser Glu Ile Arg Ser Ala Ser Ser 245 250 255 Leu Gln Val Glu Arg Ile Trp Val Asp Val Asp Asp Ser Trp Tyr Cys 260 265 270 Asp Ala Arg Phe Arg Phe Pro Ala Thr Met Arg Thr Glu Gln Leu Thr 275 280 285 Ser Leu Phe Glu Cys His Ile Gln Pro Glu Gln Thr Arg Leu Ile Ile 290 295 300 Ser Gly Lys Trp Lys Asn Gly Gly Ala Arg Leu Ala Met Leu Ser Arg 305 310 315 320 Tyr Glu Gln Gln Asp Trp Arg Val Glu Leu Leu Pro Ile Ala Met Gln 325 330 335 Lys Leu Ser Gly Ala Asp Ala Met Ala Glu Ile Ser Leu Ser Leu His 340 345 350 Glu Gly Pro Ile Leu Leu Gly His Thr Ile Pro Lys Gly Gly Tyr Glu 355 360 365 Leu Thr Glu Glu Leu Pro Trp Val Phe Glu Ala Met Asn Glu Ser Glu 370 375 380 Ser Gln Leu Lys Leu Val Gly Met Gly Ser Val Ser Ser Arg Leu Asn 385 390 395 400 Ala Leu Phe Ile Ser Leu Pro Lys Asn Ser His Leu Asp Ile Ser Gly 405 410 415 Glu Gly Glu Phe Asp Ile Pro Arg Leu Leu Lys Asn Ser Glu Arg Ser 420 425 430 Leu Thr Lys Ile Ser Gly Val Phe Ser Val Val Leu His Asp Gly Ala 435 440 445 Val Cys Thr Ile Arg Thr Gln Gln Leu Tyr Asp Ser Ala Ile Glu Tyr 450 455 460 Tyr Ile Lys Ser Thr Glu Val Glu Leu Val Lys Ser Asp Tyr Pro Val 465 470 475 480 His Arg Ala Trp Pro Lys Ile Gly Trp Lys Lys Asp Leu Gln Tyr Gly 485 490 495 Ile Val Pro Glu Lys Glu Leu Phe Trp Arg Ser Ile Arg Ser Gly Asn 500 505 510 Asn Ala Trp Tyr Ser Val Ala Ser Glu Met Pro Lys Gly Gln Ile Glu 515 520 525 Val Arg Arg Ile Val Asn Asp Glu Val Leu Phe Ser Gly Lys Val Val 530 535 540 Val Leu Pro Ala Asp Phe Asp Ile Asn Ile Ile Pro Glu Ser Ala Gln 545 550 555 560 Gln Gly Ile Ile Met Leu Ser Gly Ile Thr Asp Thr Arg Ile Asp Lys 565 570 575 Tyr Ser Asn Asn Glu Lys Val Thr Leu Lys Ser Asp Tyr Ser Gln Asn 580 585 590 Glu Cys Ala Ile Tyr Tyr Asn Ser Ser Leu Met Leu Glu Asn Thr Val 595 600 605 Asp Leu Arg Val Ser Trp Lys Asp Gly Ser Asn Leu Lys Leu Leu Leu 610 615 620 Pro Lys Pro Val Ser Gly Gly Arg Phe Val Thr Asn Asp Gly Ser Val 625 630 635 640 His Phe Asp Gly Val Ala Ser Ile Ala His Leu His Gly Ile Asp Ala 645 650 655 Glu Leu Leu Thr Ile Ser Cys Ala Gly Arg Gly Tyr Leu Asn Ile Glu 660 665 670 Leu Leu Asp Glu Asn Pro Val Ala Glu Lys Phe Arg Tyr Leu His Ala 675 680 685 Asp Leu Pro Leu Leu Ser Gly Arg Asn Asp Lys Leu Gln Gln Ile Ser 690 695 700 Leu Tyr Glu Asn Tyr Asn Leu Leu Asn Ala Met Leu Ala Cys Ala Trp 705 710 715 720 Asn Ser Asn Ser Thr Leu Cys Val Asp Phe Tyr Ser Asp Arg Phe Gly 725 730 735 Lys Asp Lys Ala Thr Leu Asn Ile Lys Arg Tyr Asp Gly Ser Phe Ile 740 745 750 Glu His Asp Gln Gly Leu Leu Val Asp Ile Lys Asn Ser Val Val Phe 755 760 765 Pro Ala Asn Arg Ile Asp Glu Leu Val Val Asp Ala Ile Ser Leu Lys 770 775 780 Asn Pro Gly Leu His Ile Ser Leu Leu Lys Lys Asp Glu Phe Ala Tyr 785 790 795 800 Asp Leu Ser Ala Leu Asn Val Gln Asp Ser Pro Trp Leu Ile Val Gly 805 810 815 Lys Leu Asp Gly Thr Ala Arg Ile Ala Pro Val Ile Lys Trp Met Leu 820 825 830 Pro Val Leu Gln Thr Asn Asp Leu Leu Leu Asn Ala Leu Cys Glu Ala 835 840 845 Asp Pro Glu Gln Arg Lys Lys Asn Phe Asn Glu Leu Ile Phe Glu Ile 850 855 860 Asp Asn Asn Pro Leu Gln Asn Tyr Cys Cys Leu Leu Thr Glu Tyr Ile 865 870 875 880 Lys Lys Tyr Lys Met Asn Asn Gly Leu Ser Leu Leu Asp Leu Asp Leu 885 890 895 Phe Arg Gly Ile Ser Ser Asn Tyr Arg Val Val Val Gln Leu Leu Ile 900 905 910 Ser Ser Cys Leu Ser Gly Asp Ser Asp Thr Ile Tyr Asp Ile Gln Glu 915 920 925 Glu Leu Pro Phe Ser Trp Gly Trp Ile Pro Val Ser Ile Trp Lys Asp 930 935 940 Val Phe Gln Lys Cys Trp Thr Tyr Leu Glu Lys Gln Ile Asn Asp Lys 945 950 955 960 Thr Leu Ala Leu His Ile Leu Gln Pro Phe Ile Ala Phe Met Asn His 965 970 975 Arg Ala His Ile Asp Arg Arg Leu Ala Pro Ile Ala Asn Met Leu Leu 980 985 990 Thr Tyr Ser Glu Ser Leu Pro Thr Gly Cys Asp Val Leu Pro Thr Val 995 1000 1005 Ser Arg Glu Gln Phe Asn Glu Ala Lys Gln Met Leu Leu Arg Asn Pro 1010 1015 1020 Asp Ser Phe Gly Arg Ile Ser Ile Phe Pro Lys Glu Leu Trp Ser Ser 1025 1030 1035 1040 Ala Ile Thr Pro Glu Leu Lys Ser Val Phe Asn Lys Leu Trp Ile Glu 1045 1050 1055 Asp Lys Tyr His Ser Arg Leu Glu Lys Arg Phe Asn Leu Met Leu Val 1060 1065 1070 Ala Ala Leu Leu Thr Gln Lys Asp Asn Asn Leu Ile His Gln Leu Ser 1075 1080 1085 Ala Leu Phe Glu Phe His Tyr Gln Gln Ala Pro Gln Gln Leu Gly Val 1090 1095 1100 Ile Tyr Gln Tyr Tyr Phe Glu Gln Ala Gly Val Cys His * 1105 1110 1115 <210> 1021 <211> 2105 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9873..16187) <400> 1021 Met Asp Val Gln Gln Leu His Tyr Ala Pro Leu Leu Asn Gln Leu His 1 5 10 15 Gln Arg Ala Val Arg Ser Val Val Ser Gln Leu Ala Leu Arg Ser Lys 20 25 30 Ser Leu Thr His Tyr Leu Glu Ser Gln Tyr Phe Gln Pro Pro Gly Gln 35 40 45 Glu Gly Ser Leu Leu Ala Asp Pro Val Phe Glu Ser Thr Phe Gly Trp 50 55 60 Met Pro Ala Asp Glu Thr Met Glu Asp Leu Arg Asp Lys Leu Ile Ser 65 70 75 80 Ser Pro Leu Val Asp Ala Leu Ser Lys Ala Pro Val Pro Phe Arg His 85 90 95 Gln Leu Thr Ala Trp Arg Thr Ile Leu Glu Asp Lys Lys Ser Leu Leu 100 105 110 Val Ser Ser Gly Thr Gly Ser Gly Lys Thr Glu Cys Phe Met Val Pro 115 120 125 Val Leu Glu Asp Leu Ile Arg Gln Gln Lys Ser Thr Arg Gln Ser Leu 130 135 140 Thr Gly Thr Gln Ala Ile Phe Leu Tyr Pro Leu Asn Ala Leu Ile Asn 145 150 155 160 Ser Gln Gln Glu Arg Leu Arg Glu Trp Thr Arg Gly Phe Lys Gly Lys 165 170 175 Ile Arg Phe Ala Leu Tyr Asn Gly Glu Thr Arg His Thr Lys Tyr Glu 180 185 190 Ile Gln Glu Asp Gln Leu Lys Val Pro Glu Gln Ala Leu Ser Arg Glu 195 200 205 Ala Ile Tyr Glu Ala Pro Pro Ser Ile Met Val Thr Asn Thr Thr Met 210 215 220 Leu Glu Tyr Met Leu Ile Arg Arg Lys Asp Ala Pro Ile Ile Glu Lys 225 230 235 240 Ser Gln Gly Met Leu Lys Tyr Ile Val Leu Asp Glu Ala His Ser Tyr 245 250 255 Ile Gly Ser Gln Ala Ala Glu Leu Ala Leu Leu Leu Arg Arg Val Met 260 265 270 Gln Ala Phe Asn Val Gly Pro Gly Thr Asp Lys Pro Val Gln Ile Ile 275 280 285 Ala Thr Ser Ala Thr Ile Gly Glu Asp Ser Pro Glu Gly Asn Lys Glu 290 295 300 Leu Ala Lys Phe Val Ala Asp Leu Ala Gly Val Thr Glu Arg Asp Val 305 310 315 320 Lys Val Val Arg Gly Tyr Arg Gln Ile Pro Arg Val Ser Glu Ser Leu 325 330 335 Ile Arg His Glu Tyr Pro Thr Ser Leu Thr Ser Leu Lys Ser Leu Ser 340 345 350 Pro Gln Asp Leu Tyr Gln Gln Leu Cys His Tyr Arg Val Ala Gln Gln 355 360 365 Leu Arg Gln Ala Leu Thr His Pro Gly Arg Gln Ala Val Arg Leu Ser 370 375 380 Glu Leu Leu Asn Val Ala Arg Arg Thr Trp Pro Asp Ile Asn His Arg 385 390 395 400 Glu Leu Leu Gln Leu Leu Asp Leu Met Ala Arg Ser Arg Glu Gly Glu 405 410 415 Leu Ala Phe Thr Pro Leu Arg Met His Gly Phe Ile Arg Thr Leu Ala 420 425 430 Gly Leu Trp Ala Cys Ser Asn Lys Gln Cys Ser His Lys Ala His Glu 435 440 445 Leu Asn Gln Ser Asp Trp Pro Phe Gly Gln Val Trp Phe Glu Gln Arg 450 455 460 Gln Tyr Cys Asp Cys Gly Ala Pro Val Phe Glu Val Leu Arg Cys Ser 465 470 475 480 Gly Cys Gly Ser Ala Tyr Leu Ser Ala Lys Glu Glu Met Arg Gly Asp 485 490 495 Gly Thr Asn Trp Leu Val Ala Gln Pro Ala Ala Ala Glu Val Asp Glu 500 505 510 Phe Ala Leu Asp Val Asp Val Tyr Ser Glu Asp Glu Asp Asn Asp Glu 515 520 525 Leu Asp Asn Asn Ser Gln Phe Asp Arg Leu Ile Ala Ser Asp Gly Glu 530 535 540 Lys Tyr Ile Ile Ser Leu Glu Glu Thr Thr Ala Gly Lys Ile Asp Ser 545 550 555 560 Glu Ala Gln Lys His Tyr Glu Ile Asn Leu Leu Arg Pro Glu Ser Arg 565 570 575 Gly Glu Gly Arg Asn Asn Ser Phe Ala Cys Val Cys Cys Gly Asp Thr 580 585 590 Gln Arg Lys Asn Asn Pro Leu Phe Arg Pro Leu Arg Leu Gly Ala Pro 595 600 605 Phe Phe Leu Asn Glu Ile Ile Pro Thr Leu Leu Glu Phe Ser Pro Leu 610 615 620 Pro Gln Thr Arg Glu Glu Gln Leu Gly Pro Phe Asn Gly Arg Arg Leu 625 630 635 640 Leu Thr Phe Thr Asp Ser Arg Gln Gly Thr Ala Arg Ile Ser Ala Arg 645 650 655 Leu Gln Gln Asp Ala Asp Lys Ala Thr Leu Arg Ala Leu Cys Tyr Gln 660 665 670 Glu Leu Ala Asn Ile Thr Glu Pro Ser Ala Lys Leu Ser Pro Ala His 675 680 685 Cys Ala Leu Leu Glu Lys Val Ile Ser Gln Phe Ser Val Leu Pro Leu 690 695 700 Lys Asn Ser Ile Asp Ala Leu Lys Lys Ala Met Ala Ala Asn Glu Glu 705 710 715 720 Leu Ser Pro Thr Asp Ile Gln Ala Leu Lys Ile Ile Glu Pro Met Val 725 730 735 Ser Ser Leu Ser Thr Glu His Ala Glu Ala Met Gln Ile Leu Gln Ala 740 745 750 Asn Ser Gly Asn Gln Gln Lys Lys Thr Met Ser Trp Gln Thr Leu Ser 755 760 765 Glu Gln Leu Val Gly Ser Val Asp Leu Ala Asp Arg Met Arg Gly Ser 770 775 780 Phe Lys Glu Leu Ser Gly Leu Asp Leu Thr Lys Gln Gln Phe Ala Asp 785 790 795 800 Phe Cys Leu Tyr Ser Glu Phe Gly Arg Arg Pro Lys Asn Ala Trp Thr 805 810 815 Leu Glu Ser Leu Gly Leu Val Ala Ile His Tyr Pro Phe Ile Asp Lys 820 825 830 Val Thr Thr Cys Pro Gln Asp Trp Lys Thr Leu Leu Pro Asp Pro Asp 835 840 845 Lys Gln Leu Ala Glu Trp Arg Asn Leu Leu Lys Ile Thr Leu Asp Phe 850 855 860 Phe Ile Arg Glu Asn Ser Ala Val Phe Tyr Glu Asn Glu Gln Tyr Pro 865 870 875 880 Arg Trp Met Gly Ala Arg Phe Pro Val Lys Met Leu Gln Gly Pro Asp 885 890 895 Lys Lys Asn Lys Gly Gln Lys Arg Asp Gln Leu Trp Pro Gln Ile Arg 900 905 910 Asp Arg His Tyr Asn Arg Val Ile Lys Leu Leu Ile Ala Val Phe Pro 915 920 925 Ala Ile Gln Pro Glu Gln Ala His Trp Lys Ser Leu Val Asn His Leu 930 935 940 Met Ile Glu Val Trp Asp Ala Ile Arg Pro Cys Leu Arg Gln Phe Glu 945 950 955 960 Ser Gly Tyr Gln Leu Asp Ile Lys Gln Gln Ala Glu Phe Tyr Ser Pro 965 970 975 Lys Gln Val Trp Arg Cys Pro Tyr Thr Arg Arg Ala Leu Asp Val Thr 980 985 990 Leu Leu Gly Tyr Ser Pro Tyr Leu Pro Gly Ser Lys Glu Ile Ala Pro 995 1000 1005 Glu Lys Ala Val Leu Ile Glu Met Pro Glu Leu Pro Val Arg His Trp 1010 1015 1020 Arg Leu Ser Gly Gly Gly Glu Ile Ala Arg Glu Glu Arg Leu Glu Trp 1025 1030 1035 1040 Leu Glu Ser Asn Ala Leu Ile Gln His Ala Arg Glu Glu Gly Leu Trp 1045 1050 1055 Ser Thr Arg Ser Asp Arg Leu Ala Leu Lys Asp Ser Trp Tyr Arg Leu 1060 1065 1070 Glu Glu His Ser Ala Gln Arg Thr Pro Glu Gln Asn Gln Phe Asn Glu 1075 1080 1085 Lys Gln Phe Lys Ser Gly Lys Val Asn Val Leu Asn Cys Ser Thr Thr 1090 1095 1100 Met Glu Met Gly Val Asp Ile Gly Gly Met Ser Leu Val Ala Met Asn 1105 1110 1115 1120 Asn Val Pro Pro Ala Pro Ala Asn Tyr Leu Gln Arg Ala Gly Arg Ala 1125 1130 1135 Gly Arg Arg Gly Glu Ser Ala Ser Ala Ala Ile Thr Leu Cys Lys Asn 1140 1145 1150 Thr Ala His Gly Met Glu Val Phe Lys Asp Pro Leu Trp Ala Phe Asn 1155 1160 1165 Thr Thr Ala Ser Ala Pro Arg Val Arg Phe Gly Ser Ser Ser Ile Val 1170 1175 1180 Gln Arg His Val Asn Ala Leu Val Leu Gly Leu Phe Leu Arg Ala Glu 1185 1190 1195 1200 Val Pro Asp Ala Thr Lys Leu Ser Cys Lys Trp Phe Phe Glu Gly Asp 1205 1210 1215 Glu Ser Gln Cys Leu Arg Phe Leu His Trp Leu Asn His Gln Ala Asp 1220 1225 1230 Gln Leu Ala Asp Lys Leu Lys Arg Leu Thr Gln Gly Thr Val Leu Met 1235 1240 1245 Ser Leu Thr Ala Thr Gln Leu Leu Thr Arg Thr Gln Ala Met Met Gln 1250 1255 1260 Gln Val Asp Ile Arg Trp Arg Ser Gln Leu Ala Ile Leu Leu Glu Asn 1265 1270 1275 1280 Ile Glu Ala Leu Lys Ala Asp Asn Ser Ala Trp Glu Glu Thr Pro Ala 1285 1290 1295 Gly Lys Ala Ile Ala Tyr Gln Leu Arg Asp Tyr Arg Gly Ala Tyr Leu 1300 1305 1310 Phe Ser Lys Leu Ile Ser Glu Ala Phe Leu Pro Gly His Gly Phe Pro 1315 1320 1325 Val Gly Val Val Asn Phe Asn Tyr Leu Thr Ala Asp Glu Leu Glu Lys 1330 1335 1340 Arg Arg Ala Ile Lys Ala Thr Gln Ala Asp Pro Asn Glu Gly Gly Glu 1345 1350 1355 1360 Ser Phe Ser Arg Arg Ile Glu Lys Leu Pro Ser Arg Asp Leu Pro Thr 1365 1370 1375 Ala Leu Arg Glu Tyr Ala Pro Gly Ala Asp Val Val Leu Gly Gly Lys 1380 1385 1390 Val Tyr Arg Ser Ser Gly Ile Met Leu Gly Lys Val Leu Ala Ser Gly 1395 1400 1405 Gln Glu Leu Ser Gly Asp His His Ile Pro Trp Phe Trp His Cys Arg 1410 1415 1420 Lys Cys Gly Ala Gly Ala Thr Ser Thr Thr His Pro Val Glu Cys Ser 1425 1430 1435 1440 His Cys Lys Ala Asp Ile Gln Gln Leu Asp Val Lys Arg Tyr Leu Gln 1445 1450 1455 Pro Val Gly Phe Ala Thr Asp Ile Arg Tyr Gln Ala His Asn Asp Val 1460 1465 1470 Ser Met Pro Ala Gln Leu Pro Trp Lys Asp Pro Arg Val Leu Val Pro 1475 1480 1485 Ser Ser Val Trp Val Ser Leu Pro Asp Ala Gly Leu Gly Arg Tyr Arg 1490 1495 1500 Phe Ser His Ser Gly Glu Leu Phe His Phe Ser Glu Gly Glu Phe Gly 1505 1510 1515 1520 His Gly Tyr Ala Ile Cys Leu Ser Cys Gly Arg Ala Glu Ser Gln Thr 1525 1530 1535 Gln Pro Gln Arg Thr Pro Glu Asn Leu Lys Asn Pro Glu Arg Glu Asn 1540 1545 1550 Thr His Tyr Leu Leu Arg Gly Gly Ser Asn Asp Arg Gln Gly Ser Asn 1555 1560 1565 Lys Leu Cys His Gly His Val His Lys Asp Leu Trp Leu Gly Tyr Ser 1570 1575 1580 Ser Arg Thr Asp Met Val Glu Leu Gln Leu Asn Asp Asp Asn Gly Leu 1585 1590 1595 1600 Leu Ile Arg Asp Glu Val Ala Ala Arg Ser Leu Ala Val Ala Leu Arg 1605 1610 1615 Glu Gly Leu Ala His Lys Leu Gly Ile Glu Asn Thr Glu Leu Gly Val 1620 1625 1630 Thr Thr Gln Gln Ala Arg Asp Ile Asn Gly Tyr Thr Gly Tyr Ser Ile 1635 1640 1645 Phe Ile Tyr Asp Asn Asn Ala Gly Gly Ala Gly Tyr Ala Val Gln Leu 1650 1655 1660 Ile Asp His Trp Ala Asp Val Phe Asn Tyr Ala Arg Lys Leu Leu Asp 1665 1670 1675 1680 Cys Ser Cys Asp Lys Phe Cys His His Cys Leu Leu Ser Tyr Asp Ser 1685 1690 1695 Gln His Tyr Val Asn Arg Leu Asp Arg His His Ala Leu Thr Leu Leu 1700 1705 1710 Thr Asn Val Arg Leu Gln Arg Leu Asn Leu Ala Pro Glu Tyr Gln Tyr 1715 1720 1725 Phe Gly Asp Gly Ser Arg Val Glu Thr Asn Pro Leu Ser Leu Arg Ile 1730 1735 1740 Ala Gln Cys Leu Asn Ser Glu Ile Tyr Asp Ser Cys Ser Leu Val Leu 1745 1750 1755 1760 Ala Gly Pro Gln Glu Gln Trp Asp Phe Ala Gln Trp Pro Leu Phe Lys 1765 1770 1775 Glu Leu Leu Gln Phe Ala Ser Ser Gly Gly Asn Val Glu Leu Leu Val 1780 1785 1790 Ala Thr Pro Leu Ala Asn Leu Thr Asp Ser Ser Arg His Gln Leu Ser 1795 1800 1805 Ala Leu Ala Ala Met Pro Gly Gly Arg Leu Gln Val Lys Ser Ile Ala 1810 1815 1820 Thr Ala Gln Leu Met Gln Gly Lys Gly Arg Trp Leu Ala Gln Val Thr 1825 1830 1835 1840 Arg Glu Gly Gln Ser Gln Gln Trp Ala Ala Asp Asp Ser Ala Thr Val 1845 1850 1855 Ala Pro Gly Glu Leu Trp Gly Gln Ser Ala Ser Ser Pro Val Val Thr 1860 1865 1870 Leu Lys Gly Thr Ser Gly Lys Thr Phe Ser Gly Gln Thr Leu Ser Ala 1875 1880 1885 Glu Asp Leu Leu Pro Ala Leu Pro Thr Gly Ala Val Arg Ile Asn Leu 1890 1895 1900 Cys Glu Gln Leu Asp Gly Pro Leu Glu Gly Phe Gly Ser Arg Phe Trp 1905 1910 1915 1920 Ser Leu Val Thr Gln Gln His Ala Gly Trp Lys Gln Ala Phe Thr Arg 1925 1930 1935 His Lys Glu Ile Thr His Val Glu Tyr Ser Asp Arg Tyr Leu Asn Ser 1940 1945 1950 Pro Phe Thr Ala Arg Leu Leu Gly Glu Ile Leu Thr Glu Leu Val Glu 1955 1960 1965 Gln Gly Met Ala Glu Arg Ala Ser Leu Thr Val Cys Val Lys Lys Leu 1970 1975 1980 Asp Tyr Asn Ser Arg Gln His Asp Ala Leu Tyr Asn Ala Trp Leu Asn 1985 1990 1995 2000 Glu Glu Asp Arg Gln Gln Val Val Thr Thr Leu Leu Glu Glu Gly Tyr 2005 2010 2015 Leu Gly Pro Ala Trp Pro Gly Ala Ile Ser Trp Leu Thr Gly Asp Asn 2020 2025 2030 Gln Ser Thr Glu His Gly Arg Glu Leu Thr Val Thr Phe Ser Asp Gly 2035 2040 2045 Ser Gln His Tyr Val Leu Leu Asp Met Gly Leu Ser Tyr Trp Arg Cys 2050 2055 2060 Ile Glu Asp Thr Phe Phe Asp Phe Ala Leu Arg Val Pro Gln Gln Val 2065 2070 2075 2080 Glu Arg Leu Ala Asn Thr Arg Ala Arg Ala Val Ala Pro Gly Asn Asp 2085 2090 2095 Leu Arg Ser Tyr Ile Ile Ala Gly * 2100 <210> 1022 <211> 944 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16438..19269) <400> 1022 Met Arg Val Val Ile Arg Asp Ala Glu Trp Arg Ile Arg Arg Ala Asp 1 5 10 15 Asp Ser Gly Asp Gly Gly Tyr Leu Leu Thr Cys Asp Gly Ile Ser Glu 20 25 30 Leu Val Arg Gly Lys Glu Gly Leu Phe Leu Thr Lys Leu Glu Gln Lys 35 40 45 Val Glu Ile Leu Asp Pro Ala Lys Thr His Leu Val Glu Asp Glu Ser 50 55 60 Ala Asn Tyr Gln Ala Ala Gln Leu Tyr Ile Glu Ser Gln Leu Arg Gln 65 70 75 80 Arg Val Pro Thr Asp Ser Lys Val His Phe Gly His Leu Ala Ala Met 85 90 95 Asp Ser Met Pro Phe Gln Leu Asp Pro Thr Arg Met Ala Leu Ala Gln 100 105 110 Pro Arg Gln Arg Ile Leu Ile Ala Asp Ala Val Gly Leu Gly Lys Thr 115 120 125 Leu Glu Ala Gly Ile Leu Val Ser Glu Leu Ile Arg Arg Gly Arg Gly 130 135 140 Lys Arg Ile Leu Val Leu Ala Val Lys Ser Met Leu Thr Gln Phe Gln 145 150 155 160 Lys Glu Phe Trp Ser Arg Phe Ala Ile Pro Leu Thr Arg Leu Asp Ser 165 170 175 Ala Gly Leu Gln Lys Val Arg Asn Arg Ile Pro Thr Asn His Asn Pro 180 185 190 Phe His Tyr Phe Asp Lys Thr Ile Ile Ser Ile Asp Thr Leu Lys Gln 195 200 205 Asp Ile Glu Tyr Arg His His Leu Glu Asn Ala Trp Trp Asp Ile Ile 210 215 220 Val Ile Asp Glu Ala His Asn Val Ala Glu Arg Gly Thr Ser Ser Leu 225 230 235 240 Arg Ser Lys Leu Ala Lys Leu Leu Ala Gly Arg Ser Asp Thr Leu Ile 245 250 255 Met Leu Ser Ala Thr Pro His Asp Gly Lys Ala Glu Ser Phe Ala Ser 260 265 270 Leu Met Asn Met Leu Asp Pro Thr Ala Ile Ala Asn Pro Lys Glu Tyr 275 280 285 Glu Tyr Ala Asp Phe Ala Asp Lys Asn Leu Val Val Arg Arg Phe Lys 290 295 300 Lys Asp Val Lys Asp Gln Met Ser Gly Glu Phe Pro Glu Arg Asn Ile 305 310 315 320 Val Lys Leu Thr Arg Leu Ala Ser Gly Ala Glu Glu Glu Ala Tyr Arg 325 330 335 Arg Leu Val Glu Ser Gln Phe Arg Asp Asp Asp Asp Glu Gln Ala Gln 340 345 350 Ser Asn Lys Gly Arg Leu Phe Lys Ile Thr Leu Glu Lys Ala Leu Phe 355 360 365 Ser Ser Pro Met Ala Cys Ala Ser Val Val Ala Asn Arg Leu Lys Arg 370 375 380 Leu Glu Ser Arg Lys Asp His Asn Ser Gln Ser Gln Ile Asn Glu Leu 385 390 395 400 Glu Ser Leu Leu Leu Ala Leu Asn Asn Ile Asp Ala Ser Gln Phe Ser 405 410 415 Lys Tyr Gln Leu Leu Leu Asp Thr Ile Arg Lys Asp Leu Ala Trp Lys 420 425 430 Ala Asn Asn Thr Glu Asp Arg Leu Val Ile Phe Thr Glu Ser Ile Lys 435 440 445 Thr Leu Glu Phe Leu Glu Gln Gln Leu Arg Ala Asp Leu Lys Leu Lys 450 455 460 Asp Asp Gln Ile Ala Thr Leu Arg Gly Asp Gln Gly Asp Thr Val Leu 465 470 475 480 Met Glu Thr Val Glu Ala Phe Gly Lys Thr Gln Ser Pro Leu Arg Leu 485 490 495 Leu Val Cys Ser Asp Val Ala Ser Glu Gly Ile Asn Leu His His Leu 500 505 510 Ser His Lys Met Ile His Phe Asp Ile Pro Trp Ser Leu Met Val Phe 515 520 525 Gln Gln Arg Asn Gly Arg Ile Asp Arg Tyr Gly Gln Lys His Gln Pro 530 535 540 Gln Ile Arg Tyr Leu Leu Thr Glu Ala Ser Glu Pro Gln Ile Asn Gly 545 550 555 560 Asp Met Arg Val Leu Glu Val Leu Ile Asn Lys Asp Glu Gln Ala Gln 565 570 575 Lys Asn Ile Gly Asp Ser Ser Glu Phe Thr Gly Lys Phe Thr Gln Glu 580 585 590 Glu Glu Glu Glu Gln Val Ala Glu Phe Met Met Gln Asp Asp Gly Ala 595 600 605 Ser Leu Phe Asp Gln Leu Leu Asn Ser Asn Val Ser Glu Ser Ala Glu 610 615 620 His Asp Leu Phe Gly Glu Ile Cys Ser Ala Val Ser Ser Asp Ala Ser 625 630 635 640 Met Val Thr Glu Thr Asp Thr Ser Leu Phe Ala Ser Glu Gln Ala Tyr 645 650 655 Cys Glu Arg Ala Leu Gly Tyr Leu Lys Ala Ser Gly Gln Thr Ile Gln 660 665 670 Tyr Glu Thr Leu Pro Asp Asn Thr Leu Ser Leu Val Ala Pro Glu Glu 675 680 685 Leu Arg Arg Arg Phe Asn Gln Leu Pro Pro Glu Ile Ala Pro Glu Asn 690 695 700 Trp Gln Leu Tyr Leu Ser Gln Asp Lys Thr Val Ile Thr Asp Ala Ile 705 710 715 720 Ala Arg Ala Arg Gly Glu Gln His Ala Trp Pro Asp Val Gln Tyr Leu 725 730 735 Trp Gln Ile Asn Pro Val Val Gln Trp Leu Asp Asp Lys Ile Ser Ser 740 745 750 Ala Phe Gly Arg His Gln Ala Pro Val Ile Arg Leu Pro Tyr Leu Leu 755 760 765 Glu Pro Asp Glu Asp His Phe Ile Leu Ser Gly Leu Phe Pro Asn Arg 770 775 780 Lys Ser His Pro Met Val Asn Pro Trp Ile Val Val Ser Phe Asn Arg 785 790 795 800 Glu Ser Leu Ile Gly Ser Gln Pro Phe Ala Glu Phe Leu Gln Arg His 805 810 815 Pro Gln Leu Ser Asn Lys Leu Thr Asn Ser Gly Gly Lys Asp Arg Asn 820 825 830 His Gln Arg Gln Gln Asp Leu Leu Glu Ala Ala Ile Ala His Ala Arg 835 840 845 Glu Val Phe Ile His Asp Arg Asn Ala Phe Glu Thr His Ile Asn Gln 850 855 860 Gln Leu Asn Glu His Leu Gln Lys Leu Asp Val Leu Arg Gly Arg Gln 865 870 875 880 Leu Ser Gln Leu Glu Leu Asp Phe Ala Asp Asn Lys Gln Gln Leu Ser 885 890 895 Val Lys Gln Ser Arg Lys Glu Gln Arg Gln Arg Glu Ile Glu His Asn 900 905 910 Phe Asp Ser Tyr Ile Glu Trp Ile Glu Asp Thr Met Thr Thr Glu Lys 915 920 925 Glu Pro Tyr Ile Gln Val Ile Ala Val Ile Thr Gly Ala Glu Gly * 930 935 940 <210> 1023 <211> 1645 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19272..24206) <400> 1023 Met Ala Leu Val Gly Ile Asn Asn Glu Asn Glu Phe Tyr Ser Asn His 1 5 10 15 Tyr Leu Gly Glu Val Phe Thr Ser Asp Ile Arg Asp Val Leu Glu Pro 20 25 30 Trp Ile Ala Gln Glu Asn Ala Ala Arg Glu Ala Glu Arg Ala Ala Arg 35 40 45 Glu Gln Gly Lys Asp Val Glu Pro Gly Tyr Arg Ala Pro Trp Asn Gln 50 55 60 Phe Asn Ser Leu Ala Thr Glu Phe Phe Arg Lys Leu Ala Glu His Glu 65 70 75 80 Lys Gln Arg Gln Ile Pro Gln Arg Leu Ala Asp Gln Arg Asn Arg Trp 85 90 95 Gln Pro Leu Leu Lys Ala Leu Gly Tyr Glu Ile Thr Pro Gln Ile Gln 100 105 110 Met Leu Asp Asp Asp Thr Pro Leu Pro Val Leu Ala Arg Tyr Asn Ser 115 120 125 Thr Asp Gly Ser Pro Trp Leu Trp Ile Val Glu Ala His Asp Gln Glu 130 135 140 Glu Gly Thr Leu Asp Pro Leu Ala Leu Ser Leu Leu Thr Ala Gln Phe 145 150 155 160 Pro Ala Asp Thr Asp Lys His Lys His Asp Ser Leu Arg Lys Lys Ala 165 170 175 Asn Gly Glu Tyr Arg Ser Trp Gln Asp Leu Leu Ser Thr Ala Val Phe 180 185 190 Thr Gln Asn Glu Pro Pro Arg Phe Val Leu Leu Leu Gly Asn Arg Gln 195 200 205 Leu Leu Leu Leu Asp Arg Thr Lys Trp Ala Gln Asn Arg Leu Leu Arg 210 215 220 Phe Asp Phe Glu Glu Ile Leu Ser Arg Arg Glu Thr Asp Thr Leu Lys 225 230 235 240 Ala Thr Ala Val Leu Leu His Lys Asp Ser Leu Leu Pro Gly Ser Gly 245 250 255 Ala Pro Tyr Leu Asp Ser Leu Asp Asp Asn Ser His Lys His Ala Phe 260 265 270 Gly Val Ser Glu Asp Leu Lys Tyr Ala Leu Arg Glu Ser Ile Glu Leu 275 280 285 Leu Gly Asn Glu Ala Met His Tyr Leu Ile Asp Arg Gly Leu Ala Asn 290 295 300 Tyr Thr Gly Asn Arg Ala Val Asp Pro Asp Glu Leu Ser Arg Glu Cys 305 310 315 320 Leu Arg Tyr Met Tyr Arg Leu Leu Phe Leu Phe Tyr Ile Glu Ala Arg 325 330 335 Pro Glu Leu Gly Tyr Ala Pro Met Thr Ala Lys Thr Tyr Leu Gln Gly 340 345 350 Tyr Ser Leu Glu Thr Leu Arg Asp Leu Glu Met Ile Pro Leu Thr Ser 355 360 365 Glu Glu Asp Arg Asn Gly Arg Tyr Phe His Asp Ser Leu Asn Met Leu 370 375 380 Phe Lys Leu Val Arg Glu Gly Tyr Asn Gly Gly Val Lys Met Gln Ser 385 390 395 400 Asp Leu Glu Ser Gly Asp Arg Ile Thr Ile His Ser His Gln Phe Ser 405 410 415 Val Pro Arg Leu Glu Ser His Leu Phe Asp Ala Asn Asn Thr Arg Ile 420 425 430 Leu Asn Arg Val Val Phe Arg Asn Glu Thr Leu Gln Gln Ile Ile Gln 435 440 445 Ala Met Ser Leu Ser Arg Pro Ala Lys Gly Arg Phe Asn Arg Arg Gly 450 455 460 Arg Ile Ser Tyr Arg Gln Leu Gly Ile Asn Gln Leu Gly Ala Val Tyr 465 470 475 480 Glu Ala Leu Leu Ser Tyr Arg Gly Phe Phe Ala Ser Glu Asp Leu Tyr 485 490 495 Glu Val Lys Lys Ala Gly Glu Glu Phe Asn Glu Leu Glu Thr Gly Tyr 500 505 510 Phe Val Ser Lys Asp Glu Ile Ser Lys Tyr His Glu Asp Glu Lys Val 515 520 525 Tyr Glu Lys Asp Gly Ser Leu Arg Ile His Arg Lys Gly Ser Phe Ile 530 535 540 Tyr Arg Met Ala Gly Arg Asp Arg Glu Lys Ser Ala Ser Tyr Tyr Thr 545 550 555 560 Pro Glu Val Leu Thr Arg Ser Leu Val Lys Tyr Ala Leu Lys Glu Leu 565 570 575 Phe Lys Glu Gln Ile Asp Pro Ile Ser Asp Pro His Ala Lys Ala Asp 580 585 590 Ala Ile Leu Asn Leu Thr Val Cys Glu Pro Ala Met Gly Ser Ala Ala 595 600 605 Phe Leu Asn Glu Ala Ile Asn Gln Leu Ala Glu Ala Tyr Leu Phe His 610 615 620 Lys Gln Gln Ala Glu Gly Arg Arg Ile Pro Gln Asp Arg Tyr Thr Gln 625 630 635 640 Glu Leu Gln Arg Val Lys Met Tyr Ile Ala Asp Asn Asn Val Phe Gly 645 650 655 Val Asp Leu Asn Pro Val Ala Val Glu Leu Ala Glu Val Ser Leu Trp 660 665 670 Leu Asn Ala Ile Ser Gly Asp Ala Phe Val Pro Trp Phe Gly Tyr Gln 675 680 685 Leu His Cys Gly Asn Ser Leu Val Gly Ala Arg Arg Gln Val Phe Asn 690 695 700 Lys Ser Glu Leu Thr Tyr Lys Lys Ala Lys Asp Pro Ser Trp Leu Asn 705 710 715 720 Ser Glu Pro Val Glu Leu Ala Met Asn Thr Pro Arg Glu Glu Thr Gln 725 730 735 Ile Phe His Phe Leu Leu Pro Asp Gly Gly Met Ala Asn Tyr Ser Asp 740 745 750 Lys Thr Val Lys Gln Arg Tyr Pro Asp Asp Phe Lys Ala Leu Asp Ser 755 760 765 Trp Arg Lys Glu Phe Ile Lys Ser Phe Ala Gly His Glu Ile Ala Asp 770 775 780 Val Gln Arg Ile Ser Glu Lys Val Glu Ala Leu Trp Asn Thr Tyr Arg 785 790 795 800 Gln Gln Leu Lys Ala Glu Arg Leu Lys Thr Ala Asp Ser Tyr Pro Val 805 810 815 Trp Pro Ala Glu Asn Ser Glu Gln Thr Arg Ser Ser Leu Ser Ser Lys 820 825 830 Asp Glu Thr Phe Ser Gly Arg Leu Glu Asp Asn Ser Ala Tyr Gln Lys 835 840 845 Leu Arg Trp Val Met Asp Tyr Trp Cys Ala Leu Trp Phe Trp Pro Ile 850 855 860 Asp Lys Ala Asp Glu Leu Pro Asp Arg Gly Thr Trp Leu Phe Glu Ile 865 870 875 880 Glu Thr Leu Leu Asp Gly Ile Val Ile Thr Glu Lys Val Thr Glu Val 885 890 895 Ala Glu His Thr Thr Gly Asp Leu Phe Ala Glu Glu Gly Leu Leu Arg 900 905 910 Glu Glu Ser Ser Leu Phe Ser Val Ala Gly Arg Leu Lys Thr Glu Val 915 920 925 Leu Phe Arg His Leu Pro Arg Leu Ala Ile Val Asp Ala Leu Arg Lys 930 935 940 Gln His Arg Phe Phe His Trp Asp Leu Glu Phe Cys Asp Leu Phe Ala 945 950 955 960 Glu Arg Gly Gly Phe Asp Leu Met Leu Gly Asn Pro Pro Trp Leu Lys 965 970 975 Val Glu Trp Gln Glu Ala Gly Val Leu Gly Asp Tyr Glu Pro Glu Phe 980 985 990 Val Leu Arg Lys Leu Ser Ala Ser Lys Leu Ala Thr Leu Arg Ile Asp 995 1000 1005 Thr Phe Asn Gln Ile Pro Ala Leu Glu Ala Ala Trp Arg Ser Glu Tyr 1010 1015 1020 Glu Gly Cys Glu Gly Met Gln Asn Phe Leu Asn Ala Gln Gln Asn Tyr 1025 1030 1035 1040 Pro Val Leu Arg Gly Val Gln Thr Asn Leu Tyr Lys Cys Phe Leu Pro 1045 1050 1055 Gln Ala Trp Arg Leu Gly Ala Gln Lys Gly Val Ala Gly Phe Leu His 1060 1065 1070 Pro Glu Gly Ile Tyr Asp Asp Pro Lys Gly Gly Gln Leu Arg Ala Ala 1075 1080 1085 Val Tyr Pro Arg Leu Arg Ala His Phe Gln Phe Gln Asn Glu Leu Asn 1090 1095 1100 Leu Phe Val Glu Val Asp His His Ala Lys Phe Ser Ser Asn Ile Tyr 1105 1110 1115 1120 Ser Ala Ser Pro Ser Thr Val Gly Phe Glu His Ile Ser Asn Leu Tyr 1125 1130 1135 Ala Pro Gln Thr Ile Asp Ala Cys Phe Glu His Ser Gly Ser Gly Asp 1140 1145 1150 Ile Pro Gly Leu Lys Asp Glu Ile Glu Ser Glu Gly Lys Leu Lys Val 1155 1160 1165 Val Trp Asn Thr Ser Gly His Arg Ser Arg Leu Ile Ser Ile Ala Thr 1170 1175 1180 His Glu Leu Glu Leu Phe Ala Arg Leu Tyr Asp Ser Glu Gly Thr Pro 1185 1190 1195 1200 Ala Trp Gln Ala Arg Leu Pro Ala Leu His Ala Lys Gln Leu Val Ala 1205 1210 1215 Val Leu Glu Lys Phe Ala Asn Gln Pro Asn Arg Leu Gly Asp Leu Gln 1220 1225 1230 Gly Gln Tyr Phe Ser Thr Val Met Phe Asp Glu Thr Tyr Ala Gln Arg 1235 1240 1245 Asp Gly Thr Ile Leu Arg Gln Thr Gln Phe Pro Gln Asp Ser Ser Gln 1250 1255 1260 Trp Val Leu Ser Gly Pro His Phe Phe Val Gly Thr Pro Phe Tyr Lys 1265 1270 1275 1280 Thr Pro Arg Glu Asn Cys Thr Leu Asn Ser Asp Tyr Asp Cys Leu Asp 1285 1290 1295 Leu Leu Thr Leu Pro Asp Asp Tyr Leu Pro Arg Thr Asn Tyr Ile Pro 1300 1305 1310 Ala Cys Asp Ala Gln Glu Tyr Ala Lys Arg Thr Pro Cys Val Thr Trp 1315 1320 1325 Thr Glu Leu Ala Glu Asp Glu Pro Lys Lys Val Thr Asp Tyr Tyr Arg 1330 1335 1340 Leu Ala Ile Arg Ala Met Leu Ala Gln Ser Gly Glu Arg Thr Leu Ile 1345 1350 1355 1360 Ser Ala Ile Tyr Pro Pro Glu Ile Ser His Met Asn Ala Val Arg Ser 1365 1370 1375 Tyr Cys Tyr Ser Ser Gln Asn Leu Leu Leu Glu His Ser Gly Met Cys 1380 1385 1390 Phe Ser Leu Pro Phe Asp Phe Ile Cys Lys Ser Thr Gly Lys Ala Asn 1395 1400 1405 Leu His Gln Met Leu Asp Gly Phe Ser Tyr Val Leu Phe Asn Pro Arg 1410 1415 1420 Gln Lys Ala Leu Leu Tyr Cys Leu Val Leu Ser Leu Asn Ser Val Asn 1425 1430 1435 1440 Asp Val Tyr Ala Gly Leu Trp Gln Ser Cys Tyr Thr Pro Asp Phe Asn 1445 1450 1455 Thr Gln Arg Trp Ser Arg Asp Leu Pro Gln Leu Pro Gln Asp Phe Phe 1460 1465 1470 Ala Lys Leu Thr Pro Glu Trp Gln Arg Asn Cys Ala Leu Arg Ser Asp 1475 1480 1485 Tyr Ser Arg Arg Gln Ala Leu Val Glu Ile Asp Val Leu Val Ala Gln 1490 1495 1500 Ala Leu Gly Leu Thr Leu Glu Glu Leu Leu Thr Ile Tyr Arg Val Gln 1505 1510 1515 1520 Phe Pro Val Met Arg Gln Tyr Glu Ala Asp Thr Trp Tyr Asp Gln Asn 1525 1530 1535 Gly Arg Ile Ile Phe Thr Pro Ser Lys Gly Leu Val Gly Val Gly Leu 1540 1545 1550 Pro Arg Thr Ala Arg Lys Ala Asp Leu Lys Asn Gly Phe Val Phe Asn 1555 1560 1565 Val Asp Ser Pro Glu Trp Thr Gly Gly Asp Cys Thr Asp Gln Ala Ile 1570 1575 1580 Gly Trp Asp Asp Val Lys His Leu Lys Thr Gly Thr Val Ser Val Thr 1585 1590 1595 1600 Phe Asp Asp Tyr Thr Arg Ser Asp Glu Gly Glu Arg Arg Thr Val Thr 1605 1610 1615 Trp Gln Ala Pro Phe Ile Lys Pro Asp Arg Glu Asp Asp Tyr Lys Val 1620 1625 1630 Ala Trp Ala Phe Phe Ala Gln Asp Lys Glu Ser Ala * 1635 1640 <210> 1024 <211> 2114 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24206..30547) <400> 1024 Met Leu Pro Ser Val Val Ser Arg Gln Val Ala Asp Ser Val Ala Ala 1 5 10 15 Phe Leu Arg Ala Ala Phe Pro Leu Asn Ser Pro Leu Phe Asn Gly Glu 20 25 30 Asn Asn Asp Asn Val Ser Met Leu Glu Gln Phe Leu Ala Gln Pro Glu 35 40 45 Thr Leu Leu Lys Gly Pro Tyr Leu Ser Ala Gln Leu Pro Phe Arg Lys 50 55 60 Ser Asp Leu Pro Leu Asn Phe Phe Pro Asn Leu Thr Leu Pro Phe Pro 65 70 75 80 Pro His Ala His Gln Ala Arg Ala Phe Gln Arg Leu Gly Ser Asp Ala 85 90 95 Pro Gln Pro Thr Leu Val Ala Thr Gly Thr Gly Ser Gly Lys Thr Glu 100 105 110 Cys Phe Met Phe Pro Leu Leu Asn His Cys Ala Gly Ala Ser Gln Ala 115 120 125 Gly Val Lys Ala Ile Ile Ile Tyr Pro Met Asn Ala Leu Ala Thr Asp 130 135 140 Gln Ala Ser Arg Phe Ala Lys Thr Ile Ala Ser Asp Pro Gln Leu His 145 150 155 160 Gly Lys Val Thr Val Gly Leu Phe Val Gly Asp Ser Glu Ile Glu Pro 165 170 175 Ser Lys Lys Met Ser Ala Glu Lys Val Ile Thr Cys Lys His Thr Leu 180 185 190 Arg Glu Ser Pro Pro Asp Ile Leu Leu Thr Asn Tyr Lys Met Leu Asp 195 200 205 Tyr Leu Leu Met Arg Pro Gly Asp Gln Pro Leu Trp Arg Tyr Asn Gln 210 215 220 Pro Gly Ser Leu Arg Tyr Leu Val Val Asp Glu Leu His Thr Phe Asp 225 230 235 240 Gly Ala Gln Gly Ser Asp Leu Ala Cys Leu Val Arg Arg Leu Lys His 245 250 255 His Ile Gly Val Asp Asn Gln Arg Phe Ala Cys Val Gly Thr Ser Ala 260 265 270 Thr Val Gly Asp Glu Leu Gly Gln Leu Leu Asp Tyr Ala Lys Thr Ile 275 280 285 Phe Asp Gln Pro Phe Thr Asp Asp Ala Val Ile Arg Glu Asp Arg Tyr 290 295 300 Thr Ala Ala Glu Tyr Leu Gln Asn Tyr Ala Ile Ala Tyr Ser Gln Tyr 305 310 315 320 Pro Gly Pro Glu Val Ala Ser Ala Leu Asp Pro Gln Ser Tyr Ala Thr 325 330 335 Pro Val Ala Tyr Leu Asn Gly Gln Ile Pro Leu Trp Phe Pro Asp Ser 340 345 350 Asp Leu Gln Leu Pro Asp Asp Leu Glu Ser Asp Asp Gly Arg Glu Lys 355 360 365 Arg Ile Ala Leu Gly Ser Leu Leu Arg Arg His Ser Val Met His Val 370 375 380 Leu Leu His Asp Leu Gln Gly Gly Ile Leu Ser Glu Arg Glu Cys Leu 385 390 395 400 Glu Asn Leu Gln Val Met Leu Ala Glu Ser Ala Asp His Ala Arg Arg 405 410 415 Val Leu Gln Ser Ile Leu Ala Leu Ile Ala Gln Ala Arg Leu Glu Val 420 425 430 Pro Glu Thr Glu His Asp Arg Gln Lys Arg Leu Gln Ala Lys Lys Ala 435 440 445 Arg Pro Val Leu Pro Phe Val Gln Leu Arg Ser Gln Leu Trp Leu Arg 450 455 460 Glu Met Arg Arg Leu Val Ala Ser Val Ala Lys Thr Pro Arg Leu Val 465 470 475 480 Phe Ala Asp Asp Val Ala Val Glu Asp Arg Glu His Tyr Leu Pro Val 485 490 495 Ile His Cys Arg Asp Cys His Ala Thr Gly Trp Ala Ser Leu Arg His 500 505 510 Gly Gln Ser Val Gln Leu Glu Thr Asp Leu Asp Gly Ile Tyr Arg Gln 515 520 525 Phe Phe Glu Lys Gly Arg Ser Ile Val Leu Ala Phe Pro Asp Asn Asn 530 535 540 Glu Lys Ala Val Ser Gly Ala His Gln Lys Leu Cys Pro Thr Cys Leu 545 550 555 560 Lys Leu Asn Arg Gln Ser Ser Val Gln Cys Gly His Cys Gly His Thr 565 570 575 Glu Leu Leu Gln Val Leu Ile Pro Asp Met Leu Lys Glu Arg Lys Asp 580 585 590 Glu Leu Glu Phe Ala Asn Glu Cys Pro Tyr Cys Asn Ser Lys Gln Gly 595 600 605 Ile Ser Ile Leu Gly Ser Arg Ala Ala Ser Leu Ser Ala Val Met Ile 610 615 620 His Gln Leu Tyr Gly Ser Gln Phe Asn Glu His Lys Lys Leu Ile Thr 625 630 635 640 Phe Ser Asp Ser Val Gln Asp Ala Ala His Arg Ala Ser Phe Phe Thr 645 650 655 Ala Arg Thr Trp Pro Leu Met Ile Arg Gly Gln Ile Ala Ser Val Leu 660 665 670 Ser Glu Lys Glu Thr Leu Pro Leu Asp Ala Phe Ala Ala Arg Val Cys 675 680 685 Gln Gln Thr Arg Glu Arg Ser Pro Asp Asp Ala His Phe Ala Ala Asn 690 695 700 Val Ile Ala Pro Asn Met Gln Trp Leu Asn Asp Tyr Gln Thr Leu Lys 705 710 715 720 Asn Glu Gly Lys Leu Ala Glu Asn Ser Asp Leu Pro Glu Leu Val Ser 725 730 735 Leu Arg Leu Asp Trp Glu Val Tyr Ser Glu Phe Thr Leu Arg Ala Arg 740 745 750 Ile Gly Arg Thr Leu Glu Ala Thr Gly Tyr Ala Val Ala Gly Val Asp 755 760 765 Lys Asp Arg Phe Asn Pro Ala Ile Thr Ala Leu His Gln Gln Leu Cys 770 775 780 Glu Glu Leu Gly Asp Glu Met Ser Gly Val Ser Val Glu Gln Val Ala 785 790 795 800 His Leu Ala Leu Gly Val Ile Trp Tyr Gln Arg Gln Ala Gly Ala Val 805 810 815 Met His Pro Ala Phe Glu Ser Tyr Arg Arg Asp Gly Thr Thr Phe Met 820 825 830 Met Thr Gln Lys Glu Arg Thr Ser Arg Tyr Met Pro Ser Ile Gly Pro 835 840 845 Lys Thr Arg Lys Pro Ala Tyr Ala Ser Phe Glu Lys Ile Asn Gly Phe 850 855 860 His Arg Leu Ile Gly Ala Lys Ser Asn Pro Ser Trp Tyr Gln His Trp 865 870 875 880 Ile Asn Arg Thr Leu Ser Asn Gly Asn Asn Leu Phe Ile Ser Ser Val 885 890 895 Ala Glu Thr Val Leu Arg Arg Leu Phe Thr Ala Leu Lys Ile Ala Gly 900 905 910 Val Val Lys Asp Phe Asp Thr Lys Gly Arg Glu Ala Trp Gly Leu Val 915 920 925 Pro Ser Ala Leu Val Val Ser Arg Asp Val Val Gln Leu Asn Cys Ser 930 935 940 Cys Cys Arg Glu Val Val Arg Ala Pro Ala Asp Gln Gly Trp Gln Trp 945 950 955 960 Arg Asn Ala Pro Cys Leu Ser Leu Arg Cys Glu Gly Arg Tyr Gln Glu 965 970 975 Val Asp Asn Thr Ala Thr Trp Arg Trp Glu Asn Met Asp Ile Ala Arg 980 985 990 Val Gln Gly Ala Glu His Thr Gly Leu Leu Ser Arg Glu Asp Arg Glu 995 1000 1005 Val Thr Glu Lys Ser Phe Tyr Arg Gly Asn Gln Pro Trp Asn Ile Asn 1010 1015 1020 Leu Leu Ser Ala Thr Pro Thr Leu Glu Met Gly Ile Asp Val Gly Asp 1025 1030 1035 1040 Leu Ser Thr Val Leu Leu Cys Ser Val Pro Pro Ala Gln Ala Asn Tyr 1045 1050 1055 Leu Gln Arg Ile Gly Arg Ala Gly Arg Lys Asp Gly Asn Ala Leu Asn 1060 1065 1070 Ile Thr Val Ala Glu Gly Asn Pro His Asp Gln Phe Phe Phe Glu Glu 1075 1080 1085 Pro Leu Glu Met Met Gln Gly Gln Val Gln Ala Pro Gly Val Phe Leu 1090 1095 1100 Asn Ala Thr Ala Ile Leu Glu Arg Gln Leu Ala Ala Phe Cys Met Asp 1105 1110 1115 1120 Asn Trp Val Lys Thr Gly Val Pro Glu Ser Ala Ile Cys Lys Asn Val 1125 1130 1135 Lys Gln Met Leu Asp Glu Leu Glu Phe Gly Arg Lys Ser Gly Phe Pro 1140 1145 1150 Tyr Asn Leu Leu Arg Tyr Ile Glu Gln His His Ala Glu Ile Ala Ala 1155 1160 1165 Gln Phe Thr Ala Ile Phe Pro Asp Leu Ala Ala Glu Thr Arg Gln Gln 1170 1175 1180 Leu Leu Ser Tyr Leu Gln Gly Ala Pro Gly Gln Arg Ser Leu Val Gln 1185 1190 1195 1200 Arg Ile Glu Glu Ala Leu Lys Leu Leu Val Glu Asp Arg Lys Ser Leu 1205 1210 1215 Arg Ser Arg Ile Asp Lys Leu Lys Arg Ser Ile Asp Lys Leu Glu Asn 1220 1225 1230 Ala Pro Arg Asp Gln Asn Phe Asp Ser Asp Met Arg Glu Leu Thr Ser 1235 1240 1245 Glu Arg Gln Ala Leu Met Ala Leu Val Asn Gln Ile Asn Asn Lys Gln 1250 1255 1260 Thr Leu Asn Phe Leu Thr Asp Glu Gly Leu Leu Pro Asn Tyr Ala Phe 1265 1270 1275 1280 Pro Glu Ala Gly Ile Thr Leu Arg Ser Val Leu Trp Arg Arg Lys Glu 1285 1290 1295 Gly Gly Glu Ala Arg Glu Tyr Gln Asn Thr Thr Phe Glu Tyr Glu Arg 1300 1305 1310 Pro Ala Ser Thr Ala Leu Ala Glu Leu Ala Pro Leu Asn Asn Phe Tyr 1315 1320 1325 Ala Gly Gly His Lys Val Glu Ile Glu Gln Ile Asp Leu Lys Val Ser 1330 1335 1340 Glu Pro Glu Asn Trp Arg Ile Cys Ser His Cys Asn Tyr Ser Glu Asn 1345 1350 1355 1360 Ile Asp Gln Thr Gly Asp Gln His Lys Tyr Cys Pro Lys Cys Gly Thr 1365 1370 1375 Pro Gly Trp Ala Asp Ala Gly Gln Lys Thr Thr Leu Leu Lys Leu Arg 1380 1385 1390 Gln Val Tyr Ala Arg Ala Ser Ala Arg Asp Ser Gln Ile Ser Asp Glu 1395 1400 1405 Ser Asp Ser Arg Glu Pro Ala Phe Phe Gln Arg Gln Leu Leu Val Ser 1410 1415 1420 Phe Glu Lys Glu Asp Val Ser Ala Ala Tyr Ala Ile Glu Glu Gly Glu 1425 1430 1435 1440 Val Pro Phe Gly Phe Glu Phe Leu Ser Lys Val Thr Leu Arg Asp Ile 1445 1450 1455 Asn Phe Gly Lys Met Ala Asp Asp Ala Asn Glu Leu Met Ile Ala Gly 1460 1465 1470 Glu Ala Lys Lys Arg Thr Gly Phe Lys Val Cys Leu Gly Cys Gly Met 1475 1480 1485 Val Gln Arg Pro Arg Asp His Glu Pro Arg His Asp Leu Ser Cys Lys 1490 1495 1500 Tyr Arg Thr Glu Pro Glu Lys Ala Lys Phe Glu Asp Tyr Leu Tyr Leu 1505 1510 1515 1520 Tyr Arg Gln Leu Glu Ser Glu Ala Leu Arg Ile Leu Leu Pro Val Ser 1525 1530 1535 Ser Tyr Ser Asn Asp Arg Val Val Glu Ala Ser Leu Gly Ala Ala Ile 1540 1545 1550 Gln Leu Gly Leu Lys His Tyr Phe Lys Gly Asn Val Asp His Leu Lys 1555 1560 1565 Gly Val Val Tyr Arg Glu Pro Glu Asn Glu Gly Glu Ser Trp Arg Gln 1570 1575 1580 Tyr Leu Val Ile Tyr Asp Thr Val Pro Gly Gly Thr Gly Ser Leu Lys 1585 1590 1595 1600 Glu Leu Met Arg Thr Pro Asp Asn Leu Leu Lys Leu Leu Glu Leu Ala 1605 1610 1615 Tyr Gln Ala Ile Val Glu Cys Ser Cys Asn Asn Asp Thr His Lys Asp 1620 1625 1630 Gly Cys Tyr Arg Cys Val Tyr Ala Tyr Arg Asp Arg Gly Arg Met Lys 1635 1640 1645 Tyr Val Ser Arg Asp Gln Ala Arg Leu Leu Leu Ala Lys Ile Leu Gln 1650 1655 1660 Ala Arg Asp Ser Ile Arg Val Ile Asp Ser Ile Lys Asn Ile Ser Leu 1665 1670 1675 1680 Glu Ala Met Met Gly Ser Glu Leu Glu Lys Arg Phe Ile Ser Cys Leu 1685 1690 1695 Gln Glu Asn Lys Asn Leu Ile Val Ser Arg Ser Tyr Ala His Gln Gly 1700 1705 1710 Ala Gly Trp Ile Ile Asn Thr Arg Ser Glu Pro Met Met Ser Trp His 1715 1720 1725 Leu Lys Ala Gln Val Asp Leu Gly Ala Lys Glu Ala Val Gly Ile Pro 1730 1735 1740 Cys Arg Pro Asp Tyr Val Leu Tyr Pro Leu Met Gln Ser Asp Ala Ile 1745 1750 1755 1760 Lys Pro Val Ala Ile Phe Leu Asp Gly Phe Ala Phe His Lys Asn Ser 1765 1770 1775 Val Ala Glu Asp Val Gln Lys Arg Gln Ala Ile Arg Asp Ser Gly Asn 1780 1785 1790 Phe Trp Val Trp Thr Val Thr Trp Ala Asp Leu Lys Glu Pro Gly Leu 1795 1800 1805 Lys His Val Gln Asp Val Leu Gly Leu Gly His Asn Pro Asp Met Lys 1810 1815 1820 Gln Pro Lys Phe Tyr Asn Leu Phe His Asp Thr Asn Phe Ala Ala Leu 1825 1830 1835 1840 Glu Ala Ser Phe Arg Glu Arg Asn Ser Phe Ala Leu Leu Leu Asp Tyr 1845 1850 1855 Leu Ala Asp Pro Gly Gly Arg Thr Gln Leu Trp Gln Arg Met Ala Ala 1860 1865 1870 Ala His Ala Trp Val Trp Leu Asp Val Lys Lys Ser Gln Asp Ala Gly 1875 1880 1885 Thr Lys Gln Lys Tyr Ala Tyr Glu Met Gln Glu Asn Ala Pro Ala Trp 1890 1895 1900 Arg Leu Ala Glu Leu Leu Pro Asp Glu Pro Phe Val Phe Gly Gly Leu 1905 1910 1915 1920 Leu Asp Ser Cys Asn Ser Ser Gln Gln Phe Ile Glu Leu Ala Ser Val 1925 1930 1935 Leu Pro Gln Gln Ala Ile Lys Pro Thr Thr Ser Val Ala Gln Met Arg 1940 1945 1950 Ser Trp Leu Arg Leu His Ile Cys Phe Asp Asp Arg Tyr Thr Gln Asp 1955 1960 1965 Asp Gly Tyr Glu Ala Gly Leu Asn Gly Phe Trp Arg Leu Val Asn Leu 1970 1975 1980 Leu Gln Phe Leu Pro Asp Met Thr Phe Thr Ser Arg Lys Ala Val His 1985 1990 1995 2000 Leu Pro Gln Glu Ser Val Asp Thr Lys Val Ser Ala Thr Pro Glu Ala 2005 2010 2015 Val Pro Glu Thr Asp Glu Ser Trp Ala Glu Ile Ile Glu Phe Gly Leu 2020 2025 2030 Leu Ser Ala Glu Glu Ile Ala Leu Leu Gln Ser His Ser Leu Ser Ala 2035 2040 2045 Pro Thr Leu Gly Tyr Glu Leu Gln Asn Asp Glu Gly Glu Ile Ile Ala 2050 2055 2060 Glu Ala Asp Leu Ala Trp Pro Ser Gln Lys Trp Ala Leu Ile Ile Asp 2065 2070 2075 2080 Asn Gln Glu Phe Ile Pro Leu Phe Thr Thr Arg Gly Trp His Val Ala 2085 2090 2095 Phe Gly Pro Ile Asp Glu Asn Thr Leu Gln His Leu Ser Gly Gly Asp 2100 2105 2110 Lys * <210> 1025 <211> 705 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(30544..32658) <400> 1025 Met Thr Val Gln Thr Pro Lys Val Ala Leu Ser Asp Gly Phe Leu Gly 1 5 10 15 Ala Phe Ala Arg Ile Pro Lys Ala Gln Gln Lys Lys Val Gln Glu Phe 20 25 30 Ile Ser Lys Phe Arg Gln Asp Pro Thr Ser Asn Gly Leu Asn Tyr Glu 35 40 45 Lys Ile His Asp Ala Arg Ser Lys Asn Val His Ser Val Arg Ile Asp 50 55 60 Gln Thr Tyr Arg Gly Ile Val Leu Lys Pro Glu Gln Gly Ala Leu Tyr 65 70 75 80 Met Leu Met Trp Val Asp Lys His Asp Glu Ala Tyr Asp Trp Ala Arg 85 90 95 Arg His Asp Cys Ser Ile His Pro Val Thr Gly Ala Ile Gln Val Ile 100 105 110 Asp Ile Ser Tyr Ile Lys Pro Ala Ala Glu Thr Val Val Asp Lys Pro 115 120 125 Lys Leu Phe Ala Ala Tyr Ser Ala Glu Gln Ile Leu Ala Leu Gly Val 130 135 140 Pro Pro Val Phe Ile Asp Gln Val Met Ala Leu Thr Asp Glu Ala Gly 145 150 155 160 Leu Asn Gln Leu Glu Ser Ile Met Pro Ala Glu Ala Trp Glu Pro Leu 165 170 175 His Trp Leu Ala Glu Gly Leu Asp Tyr Gln Glu Val Leu Glu Glu Phe 180 185 190 Asn Asp His Arg Asp Glu Pro Val Asp Thr Asn Asp Phe Met Glu Ala 195 200 205 Ile Glu Arg Ser Lys Arg Arg Phe His Val Val Glu Asn Glu Gln Glu 210 215 220 Leu Leu Gln Met Leu Asn Ala Pro Leu Glu Lys Trp Arg Val Phe Leu 225 230 235 240 His Pro Ser Gln Arg Lys Leu Val Glu Ser Pro Ala Asn Gly Pro Val 245 250 255 Arg Val Leu Gly Gly Ala Gly Thr Gly Lys Thr Val Val Ala Met His 260 265 270 Arg Ala Arg Trp Leu Ser Gln Arg Leu Ala Asp Lys Pro Gly Lys Lys 275 280 285 Val Leu Phe Thr Thr Phe Thr Arg Asn Leu Ala Ala Asp Ile Arg Ala 290 295 300 Asn Leu Gln Arg Leu Cys Thr Arg Glu Glu Met Ala Arg Ile Asp Val 305 310 315 320 Val Asn Ile Asp Ala Trp Met Ser Asp Gln Leu Lys Arg His Gly Tyr 325 330 335 Asp Phe Arg Val Val Tyr Asp Ser Asp Glu Gly Arg Arg Lys Cys Trp 340 345 350 Asn Tyr Ala Leu Gln Gln Ala Pro Ala Glu Leu Gly Leu Pro Asp Asn 355 360 365 Phe Tyr Ala Glu Glu Trp Gln Arg Val Val Gln Pro Asn Ala Val Tyr 370 375 380 Thr Arg Glu Glu Tyr Leu Lys Val Ser Arg Val Gly Arg Gly Thr Ala 385 390 395 400 Leu Ser Arg Ile Gln Arg Ala Lys Ile Trp Pro Val Phe Glu Glu Phe 405 410 415 Arg Ala Gln Met Ala Arg Ala Lys Leu Arg Glu Met Gly Asp Ala Met 420 425 430 His Glu Ala Ile Val Leu Phe Lys Glu Lys Gln Val Gln Leu Pro Tyr 435 440 445 Ser Ser Ile Val Val Asp Glu Ala Gln Asp Ile Gly Ala Pro Ala Phe 450 455 460 Thr Leu Ile Arg Ser Leu Val Pro Glu Ser Pro Asn Asp Leu Phe Ile 465 470 475 480 Val Gly Asp Gly His Gln Arg Ile Tyr Arg Asn Lys Val Val Leu Gly 485 490 495 Gln Cys Gly Ile Asn Val Arg Gly Arg Arg Ser Lys Lys Leu Lys Ile 500 505 510 Asn Tyr Arg Thr Thr Glu Glu Thr Arg Gln Phe Ala Val Gly Leu Leu 515 520 525 Thr Gly Val Lys Val Asp Asn Leu Asp Gly Glu Ala Asp Thr Ser Asn 530 535 540 Asp Tyr Leu Ser Leu Leu His Gly Glu Lys Pro Met Ile Thr His Ala 545 550 555 560 Ala Asp Phe Lys Glu Glu Ala Ala Thr Leu Val Lys Gln Ile Gln Ala 565 570 575 Leu Leu Ala Asn Gln Val Arg Ser Gln Asp Ile Cys Ile Thr Ala Arg 580 585 590 Thr Lys His Ala Cys Asp Arg Tyr Ala Ser Ala Leu Asn Asp Ala Gly 595 600 605 Ile Glu Thr Phe Asn Leu Gly Asn Asp Ser Gly Asp Ser Asp Ala Arg 610 615 620 Pro Gly Val Arg Val Ala Thr Met His Arg Ile Lys Gly Leu Glu Phe 625 630 635 640 Gln Tyr Val Phe Leu Val Gly Ile Asn Glu Gly Val Val Pro Glu Ile 645 650 655 Lys Ala Leu Ala Ser Asp Asp Pro Val Glu Gln Arg Asp Ala Leu Phe 660 665 670 Asn Glu Arg Ala Leu Leu His Val Ala Ala Thr Arg Ala Val Lys Gly 675 680 685 Leu Phe Val Ser Ser Ser Gly Val Pro Ser Pro Leu Leu Val Ala Asp 690 695 700 * <210> 1026 <211> 61 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33423..33605) <400> 1026 Met Thr Ala Pro Thr Gly Gly Ala Ile Arg Arg Glu Ala Thr Lys Ala 1 5 10 15 Ala Ser Glu Ile Ser Phe Lys Phe Ala Phe Gln Phe Ile Val Thr Glu 20 25 30 Met Ile Val Leu Gly Asn Thr Ala Ser Pro Gly Thr Ile Pro Lys Arg 35 40 45 Leu Glu His Leu Arg Gly Leu Trp Lys Trp Cys Ser * 50 55 60 <210> 1027 <211> 77 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33611..33841) <400> 1027 Val Glu Trp Leu Phe Arg Gln Thr Thr Gln Thr Trp Gly Ala Glu Arg 1 5 10 15 Tyr Leu Lys Asp Asp Trp His Gly Leu Gln Leu Phe Ala Ile Asp Gly 20 25 30 Ala Gln Phe Arg Thr Pro Asp Glu Pro Glu Leu Arg Glu Tyr Tyr Gly 35 40 45 Ser Ala Asn Thr Ser Thr Glu Arg Gln Ser Ala Tyr Pro Val Met Arg 50 55 60 Leu Val Ala Leu Met Asn Leu Gly Ile Thr Phe Tyr * 65 70 75 <210> 1028 <211> 81 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(33787..34029) <400> 1028 Met Pro Pro Pro Ser Thr Gln Leu Phe Ala Glu His Leu Pro Thr Glu 1 5 10 15 Trp Ile Gln His Phe Leu Thr Leu Ser Ala His Ala Thr Val Arg Arg 20 25 30 Leu Asn Leu Ser Val Asp Gly Glu Ala Gly Met Asn Leu Leu Ala Pro 35 40 45 Ala Ala Leu Ser Pro Arg Arg Val Ser Ala Trp Gly Pro Pro Arg Trp 50 55 60 Asn Gly Ser Ser Ala Arg Pro His Arg His Gly Ala Arg Asn Val Thr 65 70 75 80 * <210> 1029 <211> 31727 <212> DNA <213> Escherichia coli O157:H7 <400> 1029 agcgggtgat tttggtaagc gctaaatagc tattcgcaga catgcgtaac aattttcaga 60 aatatcatag tactatatga tcttaaatgc ttatcattga tcagtctgct atcacccgct 120 tttactggca attgtactat aatttcttag gttgcatcac cctgatgcgt ggggaaacat 180 gtatggtatt caacaaaaaa atgtttgtac tcattataat accaggcatt ctgggggtgt 240 tactgtcgtt tgctatgtca gtatttcaaa tgaatcgaga tacgacaatt accgccggta 300 ttctgttaaa acagcttgat aatgttacgc aaattgtcaa acatacgaca aagcttactt 360 ctattctggt gatgaaaccc tgcaaagata tcctggaaca attgattgct aacggagcat 420 tgacccccta tgttcgaaca acgggtctta tagaaaataa tttccaaata tgttcttcag 480 ttagcggttt caaaaaaatg aatgttaacg atgtttacgg tacgagcttt cacaataaaa 540 ataaagaatc acgcatagta tcaattagcg gtacaagttt tgtaccaggt aaaacagcca 600 tagtgttcct tatgccaata gggaatgata tgacagcttt tagtattgta gagtcacgat 660 atatctatga tctgatggat gttcttgatg atgagaatga tgattcattt tctcttcgct 720 ttactgaagg gcctgcaatt attagtggtg taaataataa tgacaggtta tatatgttaa 780 aaaaagattt taattctgcg atcagtcagg ctagtcttac agttactacg ccgatgattt 840 cattatatcc ctatgtcatt agtaatgtat tttacattct tccattatct attcttcttt 900 cttttatcct gtacttctta tggcagcgct ggatatctcg gaaaatgtcc ctggcagaag 960 aaattaagaa aggaatgtca tccggagaat tttctgtgca ttatcaacca gtatgtgaca 1020 cgacaaccaa agcgtgtctg ggggttgagg cgttaatgcg ttggcaacgc gaagatggta 1080 aaaatatatc tccggtagtt tttatccgcg ctgcagaaga ggaaaattta attataccgt 1140 taactaagca tctctttgaa ctgattattc aggatgtaca aagctggaaa gtgaaaaagc 1200 cgtttcacct tgggataaat attgccgctg aacatcttgc acatcctgat tttgttgctg 1260 atgttttaca tataaaaaat gcaatatctg ataaatttaa cattgtcctt gagattaccg 1320 aacgcaatct ggttgaagat actgatcatg cattacagaa aataaatgaa ttaaggagcc 1380 atggctgtga atttgcagtt gatgattttg gcacgggata ttgttccctt ggccttctgc 1440 aaaagttgtc tgttgattat cttaaaatag ataaaagctt tatagacacg ctcactacag 1500 cggaagacga aacgcctgtt ttagatatta ttattaagct gagtaatcga ctcaatttga 1560 taacgattgc agaaggtgtc agtacctctc accaggcgga atatcttatt cataataacg 1620 tgacattagt tcagggatac ttatatgcaa aaccaatgaa agcgacagag ttttatcaat 1680 ggtatgtaaa cagataaata attaaccaat attggaatgg ttttttattg ccttaaaata 1740 taaacaaagc catcagaagg ttattaactg gtgacaaacg ccaggagcaa caatgctgtt 1800 agtgggaaat acatatgaag cgtggtgtcc tgcctgtaga gaatacgtag ttgtaatcat 1860 tttgacgtgt aacataaaaa ttaattgagg tgtcaacttt tatgaaaaaa tcagaagtga 1920 tattttcaag gatttcatca ctaatgttat catctttttg tattttttgt attttaacag 1980 tggtgaagta aacggtatca cggaatttct tgtatgtaaa actcacatat cggcggatga 2040 agcctatctt ttttccatct accgtgtatg cgcccgtgag atacatgttt cctgtgttat 2100 tttcagaaat catatttaac gaaaaatatt gatccatttt tgtatgatcg gtgaaattaa 2160 taacatgggc attacatgat atgttttgct ctgctggttc attggcatga tgaaacgcaa 2220 tatggctcag aattgctgca ataaaagcac ataaaattat tcccgcaaac agaaaatatc 2280 tttgagtcat atgattactc cgctttataa tagagagagt tgcaattatt tggtgattca 2340 gagtttaaca tctgactaca ggtgaaagca taaaatccgc tcatgctatc atttgttgca 2400 atgtaaatgt aaggatgtat tttgcagtta atttccatct tctgcaattt ttcaataatc 2460 ggtgataaca tgtctacgga attaaagtat ttattatcat agaaataact gcatccttcc 2520 tgagtagggt gttgagcata atttgagaaa gcatctattt tttttatagt gtgggatttg 2580 ctttgaaaag ccatatcgaa aaaataagaa gatatataca ctatccccca tgccgcaaaa 2640 aaacaaacta taagtaatgt attctttgtg gtaaatatac cttttgcaat gtgattttta 2700 tttatatttt cagtgtgggt accattctct tcactctcaa cactttcatt ctcattgtga 2760 ttattgtcga gaacagttat gctgatttct tcattgattt tgaagccttt acggggcacc 2820 gttctgataa catcattaaa tatcgtcgct gagctgattt cacgaaaaga acgtcttatc 2880 atcgatatat tttgatataa agtgttggtt gcgacatcgg cactgctatc gctccagact 2940 ttttcaaaga attgattgtg tgacacgaca ctataagcgt tatctaaaag taactttaag 3000 cattttcccg caggataagt gagtatcact tcctctgatg taaggagtga tgttaactta 3060 ttagatgatg agttgaatct tacttcatca tttataatgt agatcattac attttatacc 3120 ttagttgtgt attacaaatc cagtattact cagaaaataa aggcaagaac attaagtgca 3180 ctatagtata atttcctaaa aatgcaaatc tgaattatct gatttttaag aataatcttg 3240 atttaattga aattcttaaa cgatgtatat ttctattaaa tgctttctgc agtgatgtga 3300 attaggggtt tttctgcatg tactgataaa aactgcgtat ccccgttata gggaaagaac 3360 gggacgcatc ctccacccat gacactaacc gtgtgattgg tagttccctg ctgtgcactt 3420 ctggtgaaat agaagaagct ctatgtgccg accggtactg tcttttatcc gattatttac 3480 cagtgacacc ttgatatgag gttatatcta ttattgctag gaggtaatat atgcttatgt 3540 tattatccaa agcgccaata gtaatttaga taaagattat agatcagcaa gcaaatccag 3600 tctgtttttt tgtgcgtact gcataacatc tatgatgact atatttttac gtgatacatc 3660 actacttaaa tgtatataag atttgatgtt tattattcat gctgagtttt aatgtttata 3720 tttttttatt gaaatctaaa aattacttaa attatccctt aaatattact tactcataag 3780 gagcaatgtg tgatatgagc ttttctattg aagatttttc attggatttt ttttcattac 3840 ataacaaggt ggccatcgta actggggccg cgggtgagct ggggagaggc ttatgctcgg 3900 ctctggccaa agcaggggct aatctattgt tggttgacat caaagagcct gataatagat 3960 atttgaagca tttaactcat gaaggcgttg aagttgagtt tatgacaata gacataacaa 4020 aacctgatgc atcatgcacc attattaata ggtgtctgga gcgtttcggt cagttagata 4080 ttctggtcaa taacgcgggc gtgtgtaaca ttaatcgtcc tatcgatttc aatcgaaacg 4140 actgggatcc gatgattaat ctcaacctga atgctgcatt cgatatgagc caggccgcat 4200 tgaatatatt tgtcccgcaa agaaaaggga aaattattaa tatgtgttcc gtattgtcat 4260 ttcatggggg acgttggtcg ccagggtatg cggcgactaa acatgcttta gcggggctga 4320 ccaaagcgta tgccgatgat tttgcggaat ataatattca gattaatggt atcgccccag 4380 gatattatgt gagtgaaatg accgctatta tttataataa ccctaaaata aaagagttaa 4440 taaaagggcg tataccggct caacgctggg gaagggcaca ggatcttatg ggcgcaatgg 4500 tgttcctcgc cagtgccgct tcagattatg tcaatggaca actattagtc attgatggtg 4560 gatattcaat tcgttaacga tttttggctg cgttgaggtg ttttgactgg aaaatggagt 4620 ggagagattt tgtcatttct ccacttccgg tacttcaggt gggtatagtg gttattcgtt 4680 agcgttgaac catcgcgatg agtttacata ccactcagag cattattgcg ctaattgttg 4740 ttttatctgt gcaccattat catcgagata tgtcgccgca accacaccac taacgttatt 4800 acttgctaac cagtaccgtc gttgactgaa gggttttatc atcatatcgc tttcttgctg 4860 cacctttgta gccccaatgc tgatggaggt gaaagagata ttcagtggtg ttgggttatt 4920 aagctcaata tagctactgc tgccgtcgtt acccagatgc caacttattt tacgcatagc 4980 ttcttggggc gtcatagtta cagattttgg cctgtaaaag attttaagtt gcgtattcat 5040 tgccagcgtt aaatgtgtgg gatcttgatg gggagtttct ggcggcattt cataaagatt 5100 taaccagaat gcagattcgc gatcctgggg aagtgggtca tgattataga taatccgcaa 5160 cccctgggtt cgtctcgcag ccaggcggaa aaccggtggc agcaccacaa aggggggaga 5220 agcagcttct ggggaacctt caccattatc tacccaactt tgcaccagta ccggatagtc 5280 attggtattg accagcatca gtgtcttttc ccgatcgcca tcgcgataaa taatccgtga 5340 agaagccggc atgatgccgg cttccactga ctgtacgaac aagatggtta agagcagcaa 5400 aacggatttc attgcatttt caccaatata taagccgttg cccgcacttt tcccgcactg 5460 actgtctgat ttggcagttt cttcaaccgg gcgataaaag agtaactata gctggagtat 5520 ccggggtgag tcgcaccttc taatgttgcc ccttcaaata caggatacca ccccgctgca 5580 tttcctccgg gggttaactt cgcgatgccc ggttgaccaa ccagcgtcat cgccgtatcg 5640 gggtgagcac tgttagaaat gtagatccca acgccctttg ccatctctgc tgcgtcataa 5700 ttatcagaga ccagggcgct gacgccgccg ttgctattga taatccccag tttttgcgcc 5760 gctgtatatg caccttcaga cacctggatt cctaatgctg tctgagtatc gctaatccct 5820 gattgaaccg agttactaca ctcgacgcgg acattaaaat taccggtact ttccatgccc 5880 gcattcagtt gtgcttctgc aattgtcggc agcaatacta acggcgtggc gctgcgggca 5940 acgcaggtgg cattgttgta gagtcgattg gccgaacgca ttccgtaacc aaaaccatta 6000 tcagcacccc agaaatccca atgaacagaa ctatcttcgc cgggctcatc atgaccaaat 6060 aaaatgccgc tggtaccgga aagctgaata taggcattgg gctgaacaca gttatagatt 6120 gtaccggaag gttttgcgaa tccgactcca ctactatctg tattattatt accgcaccaa 6180 cttgttgttg ctgatgtatc aggtagcgta ctgatgcgat aaagctcagc atgaagagga 6240 gggatatcct gtaagcgaat ctggatttta gttccctgag tggcataact ggtgatgggc 6300 actttcttcc agtaacgacc aagcgtcacg cccgccatgg tctgcttgag accgacaaaa 6360 gcgaaccagg tggcatagac atcactcaga ccatcaggcc cgcctgcatc gtaaaagccc 6420 cccacgcggt cgtcgccatt ggtagcgacc agaaaataga tgtttggcaa atctgttgca 6480 tcacattccc acaatacgga gcttcctgtc gcgccacctg atgtgtagtt agtgggaggt 6540 acgaccgttg tcgcgaggag tgaacctgct ggcgcaaaat aggtgtcggt catattaatt 6600 tttccgaact caataagcgc tgtccgacca tcttcagttt gacctatctg tgtgtttgta 6660 cagttagccc aagcggatga ttgtattagt gccaccaata tgatggagct aatcagaatg 6720 tgtaaaaaag tcgatttaga catcgggttt tctctgtatc aagactgaca ggtttcattc 6780 aggcggatga tagggctatt gctgtccttc ccgctgatat caaagggcaa ttggcagcta 6840 tcgttagcac cttcacccca gcgaactgac aagtggcctt ttgtctgttc tgtgcggagg 6900 taaatttgcc ccccctgacc ggctataccg acgactgtat tattctcatc cagcacatcg 6960 gctcccattg gcagttccga accatctgcc atgcgggatt taatcagcaa cgctttacca 7020 ggacgggtac ggaaaattac tttcaccgcc gcacccgcaa ccggtgctac ctgtctttca 7080 ctgtcgacca actcggcatc gccatccatt ccttgtggat cgagagatat acggttgtag 7140 cgatagggcg ttactgccgg aacaagcgca tagccactgt cattaatttc cagctgactg 7200 gagttataga cttttgcacc ttctgcgcct ttagcttcga ccagggcgaa cgtttcaccc 7260 agataaggtc cgaaagtaat gccgccacca tgcacagcca tcgcgccttg tacgttacct 7320 gaagcctgcc agtaatcctg gcccttcgat gcgttcaatc cgacggtagt ttgtgaaaaa 7380 cgtttttgca tgtttccgct aagcgtcgtc tgcttatatt gttgatcgcg catgacgttc 7440 aggctgtagt tggtggtctg tgcttcatca agcattccgg ttagcgagct ttgtaattgc 7500 gagctaccgt cagttgaatg ggtccagctg ttgctaagac ttggtacacg aggtccattg 7560 ccgccaagtg ggaatgagaa tgaaagggat gttaccgtct gcatatcatc agaattgtct 7620 ttatagccgc ccattctttg gcgtccgacg gaaaggttca tactgatgcc atggctaaag 7680 ctattgctgt aacctaactg aagctgtgta tcacggctct tgccgccacg gtagttctgt 7740 gttgaacctg acacaaacag gttgccgtaa ttcgcaaggc tctgacttaa cgtaagatcg 7800 aagcgcgact gttgacgcca ctggctggag tcccatgact gtttattgct ggcagcatga 7860 cgctctccca gcacatcagc cagatcacga tagccgctgg tagagtatcg ataacctgcc 7920 agggagacgg tggttgaagt aggctggaaa gttttactcc aggttaattg cgacatccaa 7980 ccactctgcg cttcgctttc gggaacacgc gcatgggacc aagtgaggtt tgccccaaat 8040 gcccccagcg aactgccata gactccgccc agcatcagcg cctggtagcc atcagcgata 8100 cgcgaaccac tgttaaatgt cagcgtatta gtcatcccgt gctgccaggt aaggtcacca 8160 aacatcgagt catcaccact atcctgcgtt ttacctactt ccacgttata acgggaagtt 8220 cctggacgca tcgattctgg tacggctgaa aaggggacac tgaaacgact gactgcgccg 8280 ttagcttccg taacggtgac atccagatcg ccgctgtagc tggtggggta taggtcgttt 8340 atctcgaaag ggccaggagc cacggtggtc tgatatattt catgaccgtt ttgcattacc 8400 gagactctgg cgtttgttgc ggccacgccg cgaatagtcg gcgcatagcc gcgcatggag 8460 tccggcagca tacgttcatc ggtcgcgaga ctaacgccgt gataactgag tccagagaaa 8520 aatcttccgc tggtgataag ctgccccatc attaactggc tatttatggc gggcagcggg 8580 cgttgcaaat agctacgaat attgttccac tgattccctt tgtcattatc ccaggtcatg 8640 ttggataact gacgatattg ccaggcacca aggttgatgc caccattaaa tgatgcccat 8700 agcgaacgct ggctatgagc attctgccct gaataggcaa cgttgtaata gttggcaata 8760 taattcatga acgccagcga tgctccggta tccagctcgc tggggggaac atagccgcga 8820 gggcgactaa tcaattgact ctgtggcacc gataagtcca ggcgcaattg tgacaactgt 8880 gtctggctgg tgatgccggg agcgagttcc ttagcaaacg tacagacagg atctttttcc 8940 cccttatctt cccctgtttt gaggcctatc gcgtccgcga cttcaggcgt caggcagggc 9000 agaacgcgac catcagcggc ttctttaaac gtgacattcc aactgcctga caacttattg 9060 ttggtgtaga tatccatttt ataattgccc ggtgcaacag actcacgtgt tgtcagtttt 9120 gctaatgacg actgactaaa tctgctgccg cggaagagtt gcgggtcaaa ggtgtagttg 9180 tcttcatctg acggtgttgc gggtgagatt tcgctcccca tgaccggttg gcaaagtaaa 9240 accaacattg ccgcagaaat tgacacaacg gatttattca tctcgacgta ctcgtgcgtg 9300 aaaaaggata ccgctcaaaa aaggagaaag aggttataag gcatgctcag acgtaacatt 9360 tacgccatag tcgttgacgg tcactaaatg gatctgcgca ccgggagcga cactgatgcc 9420 agagggtagt gtccattcag ttgtgctttg aggagcaatc attaccgaat tcgcgagggg 9480 gactttttta ccattattaa gcagttcagc ggcgcgaatt gtgacgtaat agcccgtggg 9540 attcgtcact tcaatgcggt tctgttttac ctggtaagtc aggtttttgg gtgcgtcact 9600 ggatttaccg acaatcgagc tgggacgata gaaaattttg actcgattag tcagggccag 9660 gatgagctgg ttctgacttt tatcattctt attcagataa ggtagttgac tgaaactaaa 9720 ccagaaaaca gactcgcgat cctgcggtaa attattacca gtgtagagca ggcgtaacgc 9780 ctgacctgcg gcagcttcca tgcgaaatgt ctgcggggtt ggcataaacg gtacattctt 9840 gtcagaacca cgttcatcct caacatggat attaatgata tagggctgat cgctggtatt 9900 tcgcaactgg atggtttttt cctttgcgtc accagggaaa ataatacggg ttccggtcat 9960 taccacgctg gcaaacgcgc tgctgctcat gctcatggaa aatacaagta ccagtaaata 1002 0 tgcaaaaatg ttcattctta tcttttccat gtccatgaaa aatcactatt aattgtgcga 1008 0 agaaatactg gctggcattt actgccagcc agtagattaa ttagaggtag ctcagggtgt 1014 0 attctgcgac agcggtaatt ttaccggcag tggcagcagc gctatcgata acgaagtaac 1020 0 gcgcaccgaa gtcgtagctg gcttcggtat cgccaacttt cagggtcaga cccggtacgt 1026 0 tagtcgcgcc agccagagtt actgggttac cagaagtgct ggaatccatt aactgaatgc 1032 0 caaagccttt cgccgcatcg ctgctggtat cacggtttcc cataacaccc gtgctagcgt 1038 0 caacgtcgta gcccaggaag gtggtgttga ttgcctgatc tgcaccagtt ggagcctggc 1044 0 agttagacac agaaaccgta aacggcgtct ggcctgcgct ctgaccatca gctaaagttg 1050 0 caccgaagtc agccatggct acggtcggca tcaatactac tgaattggtt tgaccgttga 1056 0 tatttacgga acaggtctga tcggttactt caccctgaaa agtgactgta ggcgcagcca 1062 0 tagttgaaaa aggtaatgca atagctgcca gcagagctgc ttttttgaaa gtagaaaaca 1068 0 tattaatatc cttgaaattt agagttaata tagaacgagt taattaatgc aattgataca 1074 0 atctgacgtt tttaaaaccg gtaaatctcc ttaactgtat aagtgccttg aaaatgtaaa 1080 0 agccatcact atcacaagca atttcaaact tgttaaaaac tgatatttta tagtgactaa 1086 0 tatacttgac atcctttttt agcagggtgt gcaatattct tttgttatct atcttaaaat 1092 0 ataagtaata gatatcccac tcataccttg tcagagtcac ctgcctgact tgctggtctt 1098 0 tatcagtact tttaatcaaa gtaatgagtt tattcaattt tatatatcgg ctaatgaatg 1104 0 tttgctctga aagtgaaaag aagatatttc tgtttttcat ctttcttagt gaaacaatca 1110 0 ttaaaaacct ggccaaatct ggcagttttg caagtatact tacgtcatcc actgcgacaa 1116 0 gaagtacgtt ttttgtaaag cggttgtcaa atctaagtgt acttaggtca ttattgcatg 1122 0 cattttgaga acaaaaaaaa cactcaataa aaaaacgata atggtgacct agttttgcac 1128 0 ttaatccctg aaggtaatat agatcatccg aaatgataat tacccttgtt agtaagttct 1134 0 tgttcattgc actaactcaa ttgcttgcag caaaacagcc catcttcatg gagtaaaaat 1140 0 tttgaaagtg aataaagctt tttactaaag atgtaacaat gggcattcca tatgcgacat 1146 0 aacaactgca gtaacacaac taatctttgc gtgttcttta tattagagag taacagcgtg 1152 0 atatctgtat ctctaaaaga atagcgatgt cctgcaatcg atgagcacaa tatatgacat 1158 0 tcatcacatg tataacaatt gaattttcat tcatactaat gttgaacggt aatatagtaa 1164 0 tttaatgctt gccgaaagat gataaacaga gttttattct gaataagagt gttttttgcg 1170 0 attttctcag gttgtaaatt ctgcataatg gctgaaccta ttacttttta tgtcaaaaaa 1176 0 gccgttttta taagaataaa acaacgatat ttaagagtgc tggcagcgga gaaaagggtt 1182 0 aatacagtca tttaagatta cttcagcttt tcctgtggtg agaaatgagc ggaattgtag 1188 0 cgcaatctgt aaaaacaatt cctcttaact aataaaaatc gcgaataatc attgtgttag 1194 0 attgatttgt tgcaaaataa taacaacatt attaaaatca ttacaatctt taatttagaa 1200 0 taacattttt atgaagacca gaatacgtta agggatgatg tatagcggtg attgctatta 1206 0 gatgggaatg aaagcttgcc aaaccgtttt gctcttcttt ctccctttca acgataagcc 1212 0 aggcataatg tggctgctta agccaattgt cgcaaagcca aagctctcta tatagctaac 1218 0 ctcatggtta atccgatctc agtaatacca tgagcaagaa ctctttcctt tttatataac 1224 0 tcttaagggt tacatgcgtg aatgcaaatg gtaatataat gaaatgtcgc ctgcccgtaa 1230 0 tgaccataaa gaatctaccc cgacgtaaaa gatatagaga ataagatgca gtaatgatga 1236 0 tgctttgtta atcaaataat aagatttaaa ttaattgtaa ctcaccaact ttgttgtttt 1242 0 attcggatgt ctgaaatgat gtcgtacaga aaactacata tcatttcaga cgtcctctaa 1248 0 attggatttt tttcacccaa ggagcaagga tgggggactt ttaaattatt gtgttttagt 1254 0 aagttaggtt cttcgccgtt cgatgaaaaa acaataactc ttagttgttt ttttgagtcc 1260 0 ttatttcagc ttatttttcg tgatttttta ttgcgccagg tgataggatt tgccgcaatc 1266 0 atttttgctg atattccgtg agtcatcaaa agtgatctgc atgtccaaaa tgaatagcat 1272 0 caataaggaa aacgttagtg gcgatgataa atttaagtaa ggaagcaacg gtggggaaag 1278 0 cattaacccc tattgctata cttatgatgt tgtcttttcc tgtagcttct caagcggcgg 1284 0 gattagtcat aaaaaatgga acggtatata acgccaatgg tgtgccagtc gttgacatca 1290 0 acaaacctaa cggtagcggt ttatctcata atatctggga taacctaaac gttgataaaa 1296 0 atggtgtcgt tttcaataat agcgctaatg aatccagtac ttcacttgcc ggaaatattc 1302 0 agggaaacag taatctgacc tccgggtcgg cgaaggtgat cctgaatgag gttacttcca 1308 0 aaaatccttc aaccattaat gggatgatgg aagttgcagg ggataaagcg gatctgatta 1314 0 ttgccaaccc gaatggtatt actgtaaacg gtggcggttc aatcaataca ggtaaactta 1320 0 ccttaaccac cgggacgccg gatatccagg atgacaagct ggccggttac tccgtgaacg 1326 0 gcggtaccat tacgctcggt aaactggata acgccagccc gacagaaatt ctgtcccgta 1332 0 acgtggtagt taacggcaaa gtgtctgccg atgagctgaa cgttgttgct ggcaataact 1338 0 atgttaatgc cgcaggccag gtgaccggta gcgtatccgc cacggggtcc cgtaacggtt 1344 0 acagcgtaga tgttgccaaa ctgggcggaa tgtatgcgaa caaaatcagt ctggtcagca 1350 0 ccgagaaagg tgtgggggtt cgcaacctcg gcgttattgc tgggggtgtt aatggtgtca 1356 0 gcatcgattc caaaggtaac ctgttaaaca gtaacgccca gattcagtct gcaagcacga 1362 0 tcaacctgac aacaaatggt actctggata acaccaccgg tacggtgaca tctgtaggca 1368 0 ctatctcgct taataccaac aagaatacta tcgtgaatac ccgtgcgggt aacatctcta 1374 0 cgatgggcga tatctacgtt aacagcggta cgattgacaa tactaacggc aagcttgcgg 1380 0 ctgcaggaat gctggcggtt gataccaata acgccacgct gattaactct ggtaaaggga 1386 0 gttctgtcgg gattgaagcg gggctcgtgg cgctgaaaac cggaacgctc aacaacagca 1392 0 atggtcagat tcgcggtggc tatgtgggtc ttgaatccgc tgcgctgaat aacaacaacg 1398 0 gtgatatcca gaccaccggc gatatcgcca ttatcagtaa cggtaatgtg gataacaaca 1404 0 aaggtctgat ccgttcgtcc accgggcata tcgttattgg cgcggcaggt agcgtaaata 1410 0 atggttcaac caaaaccgcc gataccggca gttctgactc tctgggcatt attgcagata 1416 0 ccggcgtaga aattggtgcg aacaacatca ataacaacgg cggacagatt gcgtctaatg 1422 0 gcaacgtctc cctgtcaagt tacagcacga tcgacgacta tgcgggcaaa attctgtcca 1428 0 acagcaaagt gattatcaag ggaagctctc tgcgtaacga taccgggggg atcagcggta 1434 0 agcagggtat tgaagtcgcc gttggcggca gcctgaccaa taatattggc gtgatcagct 1440 0 ctgaagaggg tgatatctcc ctgttagcca actccgtgga taaccacggc ggcttcatga 1446 0 tggggcagaa catcacgatg gagtcgatgt ctggcgtcaa taacaacaca gcgctgatcg 1452 0 tggccagcaa aaaactgaag ataaatgcgc gcggcagtat cgaaaaccgc gatggcaata 1458 0 acttcggtaa tgcttatggt ctgtacttcg gcatgcctca gcaaacgggt ggaatggtcg 1464 0 gcaaggaagg catcgagctt tccgggcaga acatctataa caacaacagc cgtcttatcg 1470 0 ctgaggatgg tcctctgact ctgcaggcgc agaacacgtt cgacaacacg cgtgctctgg 1476 0 tcaccagcgg ggcggatgca tctattcagg ttggcggaac gtattacaac aactacgcta 1482 0 ccacctggag tgcgggcaac ctggatatcg acgcgaccac gctgcaaaac agcagcagcg 1488 0 gtacgatgat cgataacaat gcgaccgggt tcatagcatc tgataaaaac ctgtcactgg 1494 0 aagtggtgaa tagccttacc aactacggct ggatcagcgg taaaggcgat gttgatgtca 1500 0 cggtgaataa cggcaacctg tataaccgca ataccattgc ggctgaaaag gggctggata 1506 0 ttgccgcgtt gaacggtatt gaaaactgga aggatatttc tgctggcggc gacctgacga 1512 0 tgaacaccaa tcgccatgtg accaacaact ccaacagcaa tatggtgggg cagaatattg 1518 0 ttattaacgc ggttaacgat atcaacaacc gtggcaacat tgtcagtgac gctgacctga 1524 0 acgtgacgac caaaggcaac ctgtataact atctctatat ggtagggtat ggggatatcg 1530 0 cattgtcggc aaatagcgtg gcgaacaata acgcgaccat cgaagcgaca ggcgatctga 1536 0 ttatcgattc gaagggtaac gtgggtaaca accgcggtaa tctgcatgcg ttgaacggcg 1542 0 tgttgtctgt taaaggcaac aatctgaaca acgataacgg tgaaattcgt ggttatggcg 1548 0 atgtcacgct ggcactgacg ggcaactacg acagctataa gggttcgctg acctctgaaa 1554 0 cgggcgacgt gactctgacg gcgaacattg tagacaacgc ctatggtttg attgccggtg 1560 0 agaatgtttc tgtcgatgct aaatcgacga tttacaacaa cactgcgctg atcgcggcga 1566 0 ataaaaagct ggttattaac gctggcggca acctcgaaaa ccgcgacggg aataacttcc 1572 0 tgcgtaataa cggcgcgctg tttggaatta ccgacaacgt tggcggcatc gtaggtaaag 1578 0 aaggtgtcac gctttctgct cagaacgtct acaacaataa cagcagcatc atcgctgaaa 1584 0 atggtccgct taatctgctg tccaggggaa cgctggataa tacccgcgcg cttcttagca 1590 0 gtggggctga tgccatcatc cgtgcggcag ggacgttcta caacaactat gccaccacgt 1596 0 acagcgccgg taatctcgac gtttatgcgg cgtcgttgaa caacgccagc gatggtcgcc 1602 0 tggaagacaa taccgccacg ggcgtgattg cgtctgacaa aaacctggat ctgagcgttg 1608 0 ataacagtgt cactaactat ggttggatca gcggtaaagg agatgtgcat ttcaatgttc 1614 0 tgaaaggcac gctgtataac cgtaatgcca tcgcggcgga caacgcgctg accattaatg 1620 0 ccctgaacgg tgttgagaac tttaaagaca ttgtggcggg tactgcgctg actattgata 1626 0 cgcagaagta tgttaccaac aacagcaaca gtaatatgtt gggacaaacc atcgcgatca 1632 0 atgccgtgaa tgacattaat aaccgtggaa atattgtggg tgattattct ctgggtgtta 1638 0 aaaccaccgg taatatttat aactacctca atatgctgag ttatggtgtc gctggcgtat 1644 0 cggcaaataa ggttacgaat agcggtaaag acgctgttct cggtggcttc tacggtttag 1650 0 cgttagaagc aaacgaaact gataacaccg gtactattgt cggcatgtaa gatgtaacca 1656 0 aagacagcag tggcttttaa tattaatgcg tcatgtcacg caggggttgc tgctgtcttt 1662 0 atttagtttg agaagataat gcaattacga tttaattttg gtttgctgct cattctttgt 1668 0 tgttttcagg ttgcagcgaa agacagtctt gataatttga tcaagcagca aaaaaatgca 1674 0 gatgaaagca cgttgcgcgc gcataaatta gaaaaaaaag atgtttactc aaatgcacaa 1680 0 cgtaatgcgt ttactctggg tgatctgccg caggaaaaga attgctttat cattaatcgg 1686 0 attgaactgg aagataactt tctgggtggt cagttgattt ctgaagtgca aaaagcgatt 1692 0 gccggacgtt gtgtcggtag tgctggtgtg caaaaaattg cagctgcctt gcaggattat 1698 0 tatattaatg cgggatatat cacaacgcga attagtatcc cttcgcagga tatttctaaa 1704 0 ggcaagctac gtttccaggt taatgccggg aagatagaaa aaacgattgt cgaaggtaat 1710 0 gatatcagtg aatggatgtt accttttcag cgtaacgata ttctcaatat tcgtgatatt 1716 0 gaacaggggc tggaaaatct tcagcgagta cctgacgttg atgtgaaaat taatattgaa 1722 0 ccgggaacac gggatggtta cagcatcgtt catattgata cacaccgggg gaaaaactgg 1728 0 agcgttcggg caagttacaa caattggggc gatgaagaaa cgggccgtta ccagacaacc 1734 0 tcggtgggtt atctgtttaa tccagcgaaa atgggggatc tgttttatct cgccggtacg 1740 0 cgtagtacta ccggacagta tgaaaacgtc agtagttatt attccattcc ggtggggtac 1746 0 tgggagtacg gctttttcta tagcaaaagt aaatcgcagc aggtgattcc gctttcgtac 1752 0 atctcgctgg attatgttgg catcagcgaa tacttgagcg caaaagcgac gcataccgtt 1758 0 tatcgcgata aaacaaaaaa gttcgccggt agtgcagaac tcattcgacg aaagtcgaat 1764 0 tacacgctta atggtgagga gctgacatta caggcgcggg atatgggaaa tatcaagctg 1770 0 gggctaaatt ataagcaaca gttacccggc gcgttctggg attcaaccct ctcgtggcaa 1776 0 cgctttttaa cctggttcgg tggtgaaaaa acgccggata tgcaatatgg cgacgttagc 1782 0 ccggtaagca atatctttaa ttttgagggt aactataccc gacaaataga gaatggatat 1788 0 tacaataccg ctttttttgc ccagtacgca ccgcgtgaac tgactttgca agataaaatt 1794 0 acagttggcg atcgttggag tattcgcggg tttgaaaata gcgtaggttt gtcagggaat 1800 0 gatggttttt atataaaaaa tacgctggca tttcctttgc ctggaatgaa agctaattat 1806 0 tatgccggtc ttgattttgg gcaagtgtat caggacgctt cttatggcga tgaatcactg 1812 0 gtgggctcgg cagttggtat tgatggaaac attaaaagtc ttgagtataa cttttccgtt 1818 0 tctaccccat taaagtatcc ggcgacatta gatattgatc gggtgaatgt aaattttaat 1824 0 ttttcgtacc aaatgtaaag gataacgaga ctcatgagaa tagggacaga tattgttgaa 1830 0 attgccagaa taaccaaagc cattattaat ggagagatgg ctttttatga gcgtgtttat 1836 0 acttctcatg agcgcttact cattaaccct gcagaacctg attatgaacg ggcctctgga 1842 0 ttctgggcgg cgaaagaagc gttagttaaa gcgattggtt gtggttttcg tgatggcgta 1848 0 cgtttccagg atattgaaat aaagcatgat gcagccaaag caccttattt cgttatttcc 1854 0 ggaagactac aagaaatttt tatcgggcag gggttgcaaa ataactccct gagtatttcg 1860 0 cattgccgta cccacgccat tgcgactgtc atcgtttatt aactcaacat atgtgatgaa 1866 0 tatgtacaaa tataatgatt taaatgaaaa aaccgtactg gtgacaggag ccagtggtga 1872 0 tattggactg ggtatttgcg aaaaatatct ggagcagaac tgcgatgttt atgcgctcta 1878 0 taaatccaac gacgtgcaat taacggcgct gaaagcaagc catcctgcag gcgataaact 1884 0 gcatattgtg cagtgcgatc ttgcctgccc ccagagcgtg agcgcattgt gcgaacagat 1890 0 agagcgccaa gctggcaaga ttgatgtgct ggtaaataac gcgggcatcg ttaaagacag 1896 0 cctgtttgcc tcgatgagtt atgaggattt cacccaggtt atcgaaacca acatgttcag 1902 0 cattttccgt ctgacgaaag acgcgctgat gctgcttcgt gcggcagaaa atcccgccat 1908 0 tattaacgtt gcctctattg cagcgctgat cccaagcgtc ggtcaggcga attacagcgc 1914 0 gtcaaaaggg gcgatcctag gcttcacccg cacgctggca gcagaaatgg caccctgggg 1920 0 cgtgcgcgtc aacgcggtcg caccgggaat gattgaatcg aaaatggtga aaaaagtatc 1926 0 ccgcgcagtg gtccgtgcgg taaccagtac catcccgtta cgccgtctgg gtaaatgtga 1932 0 agaagtggcg aacaccatcg tcttcttaag ttcctctgcc tccagctaca ttgtcggcca 1938 0 gaccatcgtt atcgatggcg gcctggtcat gcggtgattt atgtctaaat acacgattcc 1944 0 ttcgaaaatc ttcctcgaaa tgggcggctg gcgtcagccg ctgctgatgg tcgataaaat 1950 0 tgcagattat aaatacggtg aaaatggctt tgtcagtgtc gtgaaacacg tcacctataa 1956 0 cgaaccgtat ctactggggc atttcccgga agatccgatt atgcccgggg tgattatttc 1962 0 ggaaatcttc ggccaggcca gcgagtatct ctctttcctg accgacattt gcgatatctg 1968 0 gcgcgaacgt tttgaggaag agctgaagtc gttacgtgat attcacgcac gcattcaccg 1974 0 ccctgaaatg ctggagatta tccgtacctg gcgcagccag gtacgcggcg tgctggcggc 1980 0 tcagaacctg aaatttaaag atatcgccta tccgggtgat tctattgatg ttgtcagcaa 1986 0 attggctttt tcggatgcca gtggctttaa acactattcc gtgaccgcgt acgtcggtaa 1992 0 aaagctgatt agtcagggca ccattatcaa tttccgtgaa accaagtaat ccaataagag 1998 0 agtaaatatt atgtctacca tgaatgacgc tattgaacag cgtaaagaag ttctgatgac 2004 0 cattaaaact gagatcatcc agcgactgaa tattcaacgc gatgaagcgc aaattgatga 2010 0 tgatactgcg ctgtttggta atggttttaa actggactcc gtcgatgcaa cggaaattgt 2016 0 cgttctgctg gataaagtat ttgatatcaa gatcagcgaa agtgacgacc cgtcctatat 2022 0 gcgcagtatc aatagtctgg ccaccttcgt tattcaaaag aaaaacgatt aactacttat 2028 0 taaagaatta attatcagga cacgtttatg aaatctcttg ctgaatttca cttgaaaaat 2034 0 aatgcggtaa tgggggtata taacaaccgt accctacctt cttcttatca cgatgctatg 2040 0 accgaatata aagccgttcg tgaaaacgcg ctgctggtgg actattctca cctctctatt 2046 0 gttagcgtca tgggcgatga tgcctgggcg ctgatcaacc agctggtttc cgcagatgtc 2052 0 tccatcattc gtgatgagca ggcaatctac tcactggtgt tgaatgaaga gggcaccatt 2058 0 cgcggagacg tctatgtgct gtgcagcatt gacggttatt acctgctttc agaagatatt 2064 0 tcggctgccg aattgatcgc cagcatgaat accattctcg aaaaagcgga agaactggat 2070 0 attcaatcga tgcctgaaat tcaggatatg cgggaaaaca actggggggc aatcctgctc 2076 0 gaaggcccat actcctggga gatcatgtct gaaattcatg gctttgacgt gattggcctg 2082 0 ccttactacg aatacatgaa taccgaggag gatctgctgc tcttccgctg tggtaaacac 2088 0 ggtgagtatg cgtacatgac catcggtgag caggcgaaac tggcggagca gtgggaaaaa 2094 0 ctgttaaccg ttggcgagaa atacctgatg cagaccggcg gcctggatta tcaaaaaatc 2100 0 gtacgcctcg aaaatccgtg ctgggatgcc agcctctggg aaggtcaggc ggtgaatccg 2106 0 gttcagttgc agatgcagtg ggcggtgcag tacgacaaag atgattttat tggcaaggac 2112 0 gcggtgacag agctatccca ggagtatacc ggtaataaac tcatcggcat gatcgcacag 2118 0 gaagaatgcg aaggcattga ggctggcgat cgcgtgctgg tggaaggtca agacgtgggc 2124 0 tatgtcgtga aggcactctt ttccccagcg ttgcagcgtt tcattgccct gaccctgctg 2130 0 gaaaaggatt acgcctggtc tgacatcagc ggctacgaaa ttcaaactgc tcacggaatt 2136 0 attccggcgc aatcaaaatg tatgccgttt atttataacc tgagcatgtt ggttagccca 2142 0 actgagcaca gttatatcga cgcgtcaaaa aataaaagcg cagcgtaatg aatatcgccg 2148 0 cgtgactata gcttacgcgg cttaaattaa ccccaattgg cgggattgcc aggtattatt 2154 0 catgaaaacg aacaggaaaa gagttgttat taccgggctg gggattttgt cctcactggc 2160 0 ggaaaatatt caggatttcc gggaagcatt attaaataaa aaaaatggcg ttaaggatag 2166 0 cgaacgcttt gcaaaatggt ttgaaaatgc gcgtgcggca gaagtgttgc atgacattga 2172 0 atactccgat ctgaacgaag atgttatcga ttcactggat aacgcagcgc tctgggccta 2178 0 caaagtgggt aaagatgcgc tgagtcaggc cggcctgatg gatagccgtg acaccctcaa 2184 0 agaaacaggc atgatcgtcg gtgtttcgtc cgcgggaaca gaggcatttt tgccgctgtt 2190 0 cgaacagcgc atggaagatt tctcgctgcg taaagcactc ttttccggcg cattctcatc 2196 0 ctgttgttcc agcgtttcaa cgctgctggg cttacagggt ggggttgaac tggtggcgac 2202 0 cgcgtgtacc gccagcccga acgccgtggg gatggccttt gactacatcc agaatggtaa 2208 0 aagcaaaacc atgctggcag tgggcactga gcccatctat ctgccgacct ttgccggatt 2214 0 ctacgcactg aatgtcatgc atccagacac ttgtacgccg ttctcgggtc agtccggtat 2220 0 gtcgattggt gaaggcgctg gcgctatcgt gctggaagag tatgagcacg ccgtagcacg 2226 0 cggggcgacc atttatggtg agatcctctc ttacgccact tcctgcgatg ctttccatga 2232 0 aaccgggcca gatccgcgtg ccagcggagc ggtgcaggtc atgaacaagg caatggcaaa 2238 0 tgcgggcgta accccggagc aaatcgatta cgtcaacgcg cacggtacgg gtaccgaagc 2244 0 caatgaccgt attgaaacgc tggcaatgaa aaaggtcttc gctaaccacg ataaactgct 2250 0 ggtgagctcc accaaatctt actttggcca caacattggc gcagcgggga ttgtggaact 2256 0 gattgcctgt ctggcaacgc ttccggataa ccgcgtactg ccgacgctga atttcagcca 2262 0 tgcacgcccg aattgcgatc tggactatgt gccgaatgag tttcgcgatc gcaaagtgaa 2268 0 catcttcatg aagaataact atgccttcgg cggcaacaac tgctgcatga tcctgagcat 2274 0 ggagcccgcg tccattccgg tcagtaccta tgattcgaag cgtgtggcta tctcgggcgt 2280 0 cggtgcagta tccgcaatag gccacacgct caaccaggtt ctggaaaaca tctgggcgca 2286 0 ggaccaccac gttgaactgg gtagcgtaac cttcccggac gatacactgg aagaagccaa 2292 0 agagctgctg gccgtgctgg atgaatcaaa ccagtttgcc gagctgtttg atgaagagta 2298 0 cagcttcagc gaagctacgc ttccggaaac ggaaagcaac tttaaaacgt tccaggtttc 2304 0 cgggctggag ccgcgtaaac acctgcgtcg tttcgatcag cgtaaagcga cccgtggcgg 2310 0 cacgtttgcc ctgatcgcac tcaccgaagc gctggaacag gcgaagcgta aaatcaaacg 2316 0 cgacggcgat gagttgggca tgatcatggg gatgtcccgc ggcccgcagg aaaccaccta 2322 0 caaatatctg caaagtctga aacccgatcc acgcaaagta cgtacatcgg aatttcctgg 2328 0 ctcgctgatg aatgcgatcc caacgttctg cgggatctct gaagggatca aagggtatac 2334 0 cactacgctt gcgacagggg aaaactcggc gctgggcgcg ctgacctacg gttatgaaat 2340 0 cgtccggcag aacctgcaac cgcaggtatt ggttggcggc gcggatgagt acttcccgtc 2346 0 gatgtcgctg tatatggatg cggtgacaca aaagatccac atgacggctg aggcgagcga 2352 0 ctatcagatt tacggtaaag atccgcaagg ttatgttccg ggcgaagggg cttgcatgct 2358 0 gctgctggaa gatccgcagt tggctgtggc gcgtggcgct gaggttctcg cggaagtggt 2364 0 gggctacggc aagtcatgca gcaataccta cttcgacgcc tcattgttgg aagaaaaatc 2370 0 cgcgtcgatg gcgctggcca ttgaacgcgc ccttacgcat gcgggcatct ctgctggcga 2376 0 tattgatttg gtatgtggta ccagcaacgg tagcgatgac cattctcgta tcgaaattga 2382 0 cgcgatttac aacaccttcg ccgcgcaaaa cccggcggtg ccggtagtga actataacgc 2388 0 ttgctttggt tttgtcgcct ctgccgctgg tttgcttaac ctcgccgtga ttactgactg 2394 0 cattaagaag caggcagtac ctgcgattcc aaatacggtg gaattctttg atgagcgtgt 2400 0 gaattttgta cgccagtcga tgaaacttgc gctgaaccat gtcctgcttg ttggcgcaac 2406 0 ggaaggcggc aactactacg cgttcgtcat taagggataa gactgtggac aatgccgcta 2412 0 ttatttcggg ttacagcgtg tggatgccgt atgccgaaga ctgttcgcag ttaattgaca 2418 0 atctgaaaca ggggaaacgc gttgcgcgta caccctggtt tacctccaac gaggaagcca 2424 0 ttaaatgcgg gtttaagggt aatccgtcag tggcgacgtt gaaacaggtg gacgatagcg 2430 0 cattggacct gctgtctcag ttgatcgacg aagccctgga acaggcaatg ctggataagc 2436 0 attgcctggc cgggcgcaac gttcgcgttt atctgaccgg tattgggccg cgtatcgacg 2442 0 ggctggatta caaatctttc tataattaca acgatgtaga agatatcaac ttaacgcaat 2448 0 ccatcacaaa tctgcatgcc tcaaagatgt cgcaggacac gatttcaagc catcttgcgc 2454 0 gcaaatatcg cttgcagtat ttgccgccta acatgaactg caccagtaac tcgtcactga 2460 0 ctgcggtgca tctggcgacg cagggcattg agcagggcgg gattgatctc gcgattgtgc 2466 0 tgaactgttc gaaaattaaa acccaggaca tctggttcct ggaaacgcaa tcgatgctgg 2472 0 acagcgaaca agtgcagccg tttggtgaaa acagtaaagg tgtggcgttc gcagaaggtt 2478 0 ttagcgcgct cctactggaa agcgctcatc accgccgggc gcgtcaacaa agtgagggcg 2484 0 taagggtgca aacgacttac acccaaatca gcgcgggccg cagcaacgat gcctcctggc 2490 0 ttagcactaa cgtgcacaag gtcatgcagg ccgcgatgaa gcaggctgaa attgcgctgg 2496 0 atgatcttgc agccattctt ccacacggca acggttcggc agtgagcgat aacgcggagg 2502 0 ccaaagccat cgccatgttc gcaggggagc gacagatccc cgttctcgcc tataaagggc 2508 0 agatcggcta taccgcaacc ggatctggtg ttgtcgatct gatcattggc caccattcgt 2514 0 tgacgcatca tcaactgatc gcacctgttg gcaacgacgt cattatcgac agcatggctt 2520 0 cgctggtact tacggacggc agcgtgacaa accatagcaa acgccatttg ctgaaggttg 2526 0 gtgtgggtgt cgatggttca gttattggcg ttgtcatgac aaatatgcaa gcggggcgcg 2532 0 cgaaatgacg gaaaagagta tctacctgtc ttcctgggcg cttacggaac cggacgacat 2538 0 tttttatttt tatcagccga cctggctcaa cgcctgggaa gcacatatgt acgaaagggg 2544 0 attatacggc acccgtgcta atggctgggg actgaagcgc tttggcgtgg agaacgatat 2550 0 ttatgcacca gaacggatcc gtaatccaca atatatgcct taccttgagg cgatggagca 2556 0 ggtgaccgat tctgcattac aacaaatgcc gactaaagaa cgcatgaagt taatgaaatc 2562 0 gcgcacggca tttatttatg ccgattcctg gggcgaatcc ggttcgtttg aaaaaatttc 2568 0 cagtgcgctg catatcgcca ctattgatac gcttcccaag aatttactta agaagttttc 2574 0 gataacggaa ccgacttgca agattcgcgg cgaaaaacag gcattcgttc aggcgctgcg 2580 0 tatggcgcag gattatctcg cctgggatgt attcgataac gtggtgattt gtgctgccta 2586 0 tcgggcaatt ccggtgctgg tattctctga agaagatgtg ggtaaaccgc ctaagcgttt 2592 0 atttccccgt cgtgctgatg aggtgaattt atctgttgaa cgagtgggtt gttttattct 2598 0 cagccagcgt gagagcgcca tcaggctgca atgcggggaa tatcattccg gcactgcgcc 2604 0 acagcatgct acggatattg atgtcatggc cttcagcgaa cggcaacaaa tgccgtcccg 2610 0 gcctgctgct ggcgttatcg acctggtggc ccattacggt gaaagcggtt gtctgacgcc 2616 0 cgcgttgagt atggattatt taacccgtca tattcagccc ggtggaaaaa tgcgtacggt 2622 0 cattgccgat aaacagtttg gttatcacta ctttgacctt gaataccttg aaggataacg 2628 0 acagtcgtat gcaatctact attaaatcgt tgcccgctat ttcgcttagc aatatttata 2634 0 agtgttatgg cgctggggca ggaaaggttg atgcgcttaa aagcattaat cttgatatca 2640 0 ataaaggcga atttctcgca ctgtgtgggc cgtcaggcag tggtaaaagt actctgttga 2646 0 atattctctc gggtattgat aaaccgacca gcggaacggt gatattttta aataaattac 2652 0 tgaaccaact gccagaagag cagttggctg tgattcgtgg aaaacatttg ggttttattt 2658 0 ttcagttttt taaccttatg ccggtattaa atgttttcga taacgtttat ttcccactgg 2664 0 tgcttaatgg tcagttcagt aaaaaagaag ccactgaacg gacgctgcat tatctcgata 2670 0 gtgttggatt aagcggtttt ggcgatcgta aacctgggca actatcgggc ggtcaacaac 2676 0 agcgtgtcgc catcgccagg gcactggccc acgaaccgat ggtggtcatt gccgatgaac 2682 0 cgacgggaaa tttagacctg gcaaccggcg aggctatttt ggacctgttg ttgacgatta 2688 0 atcagcagac cggcaccaca tttgttattt ccacgcactc cagcgaatta aaagcgcggg 2694 0 cacggcgagt ggttgaaatt caggatggag tattgattca tgactcagat gcataaagga 2700 0 tttttgctca tcggcgtctt tttgtacgcg gcgtttgtgg ctccgaagat ttacgcggca 2706 0 acacccgacg ctgttaacca ggttctgcaa caggggctcc cggcgcagcc tgccgcgctg 2712 0 gcgacgctga ccgaggcgtt aaagaaagag tatgaagcca ggcacaatgt ggtggcgctg 2718 0 gttttttacg cctatggctt actgcgtcaa gcggacggtt atgcggcaac aaacgatttt 2724 0 atccatgcct cagaatacgc caaaagcggc tttttctggc tggatgaagc ggtggatttg 2730 0 caggagaaaa atcaacgcgt acggtattta cgcgcccgcg tagatgccta tttacccgca 2736 0 gactcagggc gttgcgtggt gacagtcaaa gacaccgaac acatgctggc tgacccggcg 2742 0 atatggacga caacgatccg cgaccatatt ctggcgatgc gttatcgcgc attacgtcac 2748 0 tgcaaggaca ccacccgcgc gaatgcgttg ttggcgcaaa ttaaagggca aaacgccgcg 2754 0 cttgcgcagt cgctgacgca ggattttaat gttgtaccag aatgggatag tgaagagtta 2760 0 acccaggtac tgctgccgct gatgaaaggt gagtaaatgt ccggggaaat tttagctgtt 2766 0 aattgcgttc tgctgctgat tctgtttttt gtgttttatc agcttctgtt ttattcacga 2772 0 gatgtcaaat ttgcattttt gaatctcttt cgccacaagc gtcgctcttt ttctaccata 2778 0 accgctattg tattgggtgg cgtggcaatt tttttatatg gcggatttat tgattactct 2784 0 ttctggatcc tgaaagagca gacgattcgt accaatattg gtcatgtaca aatttacaat 2790 0 cagcactatt ttgaaacgtc gaataaaaat aagagcctga ttgccgatta tgcggcgtta 2796 0 aagaaagcta ttttgtcgga cccgacgctg gcggcggata tttccacgct ctccgggcaa 2802 0 ctggagttta ctggcgtaat ttcacattac gagagcgaaa cctccagcta tttctccgcg 2808 0 ctgggggtcg agccgttacc cgctttaaag ctgggttcgt tcgataagat tatcgcgggg 2814 0 agcgatcttt cccgggtaaa aggtgatgaa atcaccctgg gcagcggtct ggcgaaaacg 2820 0 ttgaatgcga aatatgacga ctggctggat gtgatggtgg tcaacacggc gggcgggcag 2826 0 ggcgcattgt cgctaaaaat gcgtggcatt tttgagtcag gcattaaaga ttatgacgat 2832 0 gtcgcgatga agatcccgct ggacaccgcg cagcgcatga tgggtacgga tggcgtcagc 2838 0 aaagtgctta ttctgcttaa agaggatgac accgcggcgt ttagcgcaaa gctgcgtcaa 2844 0 tttatcgaac gcaatcattt gccgctggtg gtcaaagact ggcgtgatgt ttcactcttt 2850 0 tatcaacagg ttgaagggtt gctatcgggg atctatttct tcatcaagct gattgttgcg 2856 0 ctgattgtca tcttcatgat cggcaactcg atggcaatga acattgttga gcgcacccgt 2862 0 gaaattacca ctctgcgtgc cataggcctg aagccgcttc acgtcacgcg cttgtttctg 2868 0 acagaaggca tttttattgg tgtgattggc gcagtcggca gcctgctggt ggggggcgtg 2874 0 ttagcctgga ttattaatct ttatggtatt gcgatgccgc catcgccggg acaaaccatc 2880 0 ggctataccg cctttataaa aaccagtaac ccggaattga tttgggtgac ggtggtatta 2886 0 cctattttga cagcaacagg tgcctctgtg ttaccggctt tacgtgcttc ccggctgaat 2892 0 atttctgacg catttaaatt ctcatagggc taattatgaa tatggctttt tacggcaagt 2898 0 ggtttgcttg cctgtggctc gctacgtcgt gcgttcaggc ggcgagcaca gataataagg 2904 0 cgctggagat aattcgtcgc gctgacgaaa ttcgttcgcc gaataaaccg tttcgttaca 2910 0 cgctgacggt aacggaatat aaagcgggcg caacccagcc agagaataaa caggtcctcg 2916 0 atatttccat gcgctttatg aaaccgcagg gtaatgaaaa agcggatgca cgctcgctgg 2922 0 tgcgttttat ttatccgccg cgagataaag gaaaaatcat gctttccgac tggtacgatt 2928 0 tatggtttta cacgccggaa ctgcgacgtc ctatgcctat ttcacggcaa caaagattaa 2934 0 ttgggcaaat ctctaatggc gatgtcattg tcactaactt tgaatatgcc tatgactcga 2940 0 ccctgatggg ggaagtcacg tgtgctgaaa agcagtgtta caagctggcg ctggtgcgta 2946 0 aatcggcgga tatcacctgg ccgaaggtta tctattacgt tgaaaaagac ggtgataatc 2952 0 gcccgtggaa ggcggcctat tattcgcagg atgaccagtt aataaaagaa gtgttgtatc 2958 0 aggatttcca gccggtgttg gggaaaacgc gacccatgaa aataaccgtt accgatgttc 2964 0 gtcacggcaa taactattca gtgatggagt acagcgatgt tcgtctggaa tcgctgccgg 2970 0 agtttcattt caccaaagag tatattcagc gaggtgcgaa atgaaacgta cgctgaagat 2976 0 ctcttcgttg ctgtgtgttg cgctgccgtt gacggtacag gcggattgcc tgtcaggtga 2982 0 cgaggtggca caaaatagcg atgtgacgct ttacgagcag gtgtcttatg tcaataaaca 2988 0 ggcttcggcc tggcagattg caggcaaaaa tccctacacc cgtcacaacg gttatcagga 2994 0 ggcggggatt ggcatcaata gcggttgttc gataatcgac aatacgctgg accttaagct 3000 0 caatctgtat ggaataaacg aatatgcgct taaacccgca gggaaattcg aaacggatga 3006 0 tagccgcacg cgtgcgttaa ttaaccgcct cagtctggtc tatagcgcct cggacagcgt 3012 0 tcaatttgaa gcaggcaaat ttgccgcgcc gtcaggaatg ttctttttgc gttcgccttc 3018 0 tgatttgcaa acgcattatt acaccggatt ccagtcgacg cgtttgcacg atcccaaaat 3024 0 gacatcggcg tatcaggcgt catcgtgggg cgcaaaaatg agcgtggata cacgcgatta 3030 0 tgcgttttcg gcgagtgtca taccgaagtt agccaccatc gacaaacgct atgtgacgtc 3036 0 tggcaactgg tcggctaatc agcagggaaa cagcgacgaa gcctatctgc tgagcttcag 3042 0 cgatcatcgc tttggtgagc acacgccgac agtcaatgtg cggctcggac catcgccgtc 3048 0 actcgcgctg tctgacagtt atcactacac cccgcagctt acgctgaatg tcgacgcagc 3054 0 ctaccaccgc tcccagcaat ggcggcatct ttcccaccgt gagacggcgc aggtcgagga 3060 0 atatcagttt ccggattcgc tctatgaaac gaaagatgaa agcggcgtag agctggcgct 3066 0 gggtgggcag tacaccagtg ataatttcag cgtgtttggc gttgagtatt actttcagag 3072 0 cgagggttat tcgcgcgctg aacagcgtca gcagcgcgag ttaattgact tcctcaatac 3078 0 cacaaccggc tatgcgccac tggatcaggc atttgattct tacaaatacc tgatggcttc 3084 0 agaaatcagc aataccgcca atcaggggat gctgcagggt aagcactatc tgaacgcctg 3090 0 ggccagtctg ccgctggcgg gagagtcgac gctgcagcct tcgctggtgg tgaatctcgt 3096 0 tgatggcagc acgttgctgg gcctgcatta ttccacgccg ctcagcgcta taagtaacca 3102 0 gcttgaagcc tatgccggtg gctatagcgc gctgggaagt cggtactccg aatttgcgct 3108 0 ttttggcgac acgttaggcc tttatttggg ctttaaatac tatctataag gataaagaga 3114 0 tgatgaataa tgcttcacaa ccgacagtac tgctttttgc cggtcagggt aatccggtta 3120 0 ttggtatggg cagcgatctt tgggatctca acgccagtac aaaacatatc tgggattgtg 3126 0 ccagcgatat ttccggactg aacctgcgtc gcctgtgtca gaaagggccg atgaatcgcc 3132 0 ttattcaaac gacggtacaa caactggcgg tgaccgcaat taatgtaacg ctctataccc 3138 0 tgtgccgcga gcgtcttgag aatttaacgg ttgtgggctc ctgcggacac agcgttggtg 3144 0 aatacagtgc gctctacgcc gctggagcta tttctcttga gacgctattt ggcatgattc 3150 0 acttcagagc cagcctgatg catgacgaaa gccagagaaa taaaggcgca atgctggcgg 3156 0 ttaaaggcat caaccgcgaa caactgcaga cgatgattac ggaatcaggc attgcgctgg 3162 0 atattagctg tgataacacg ccgcgccagc aggttattgg gggaacgcag gctgcgttga 3168 0 atgaatttgc cacgctgctg atggccgctg gatacgaacc ggttaaa 3172 7 <210> 1030 <211> 511 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(165..1697) <400> 1030 Met Arg Gly Glu Thr Cys Met Val Phe Asn Lys Lys Met Phe Val Leu 1 5 10 15 Ile Ile Ile Pro Gly Ile Leu Gly Val Leu Leu Ser Phe Ala Met Ser 20 25 30 Val Phe Gln Met Asn Arg Asp Thr Thr Ile Thr Ala Gly Ile Leu Leu 35 40 45 Lys Gln Leu Asp Asn Val Thr Gln Ile Val Lys His Thr Thr Lys Leu 50 55 60 Thr Ser Ile Leu Val Met Lys Pro Cys Lys Asp Ile Leu Glu Gln Leu 65 70 75 80 Ile Ala Asn Gly Ala Leu Thr Pro Tyr Val Arg Thr Thr Gly Leu Ile 85 90 95 Glu Asn Asn Phe Gln Ile Cys Ser Ser Val Ser Gly Phe Lys Lys Met 100 105 110 Asn Val Asn Asp Val Tyr Gly Thr Ser Phe His Asn Lys Asn Lys Glu 115 120 125 Ser Arg Ile Val Ser Ile Ser Gly Thr Ser Phe Val Pro Gly Lys Thr 130 135 140 Ala Ile Val Phe Leu Met Pro Ile Gly Asn Asp Met Thr Ala Phe Ser 145 150 155 160 Ile Val Glu Ser Arg Tyr Ile Tyr Asp Leu Met Asp Val Leu Asp Asp 165 170 175 Glu Asn Asp Asp Ser Phe Ser Leu Arg Phe Thr Glu Gly Pro Ala Ile 180 185 190 Ile Ser Gly Val Asn Asn Asn Asp Arg Leu Tyr Met Leu Lys Lys Asp 195 200 205 Phe Asn Ser Ala Ile Ser Gln Ala Ser Leu Thr Val Thr Thr Pro Met 210 215 220 Ile Ser Leu Tyr Pro Tyr Val Ile Ser Asn Val Phe Tyr Ile Leu Pro 225 230 235 240 Leu Ser Ile Leu Leu Ser Phe Ile Leu Tyr Phe Leu Trp Gln Arg Trp 245 250 255 Ile Ser Arg Lys Met Ser Leu Ala Glu Glu Ile Lys Lys Gly Met Ser 260 265 270 Ser Gly Glu Phe Ser Val His Tyr Gln Pro Val Cys Asp Thr Thr Thr 275 280 285 Lys Ala Cys Leu Gly Val Glu Ala Leu Met Arg Trp Gln Arg Glu Asp 290 295 300 Gly Lys Asn Ile Ser Pro Val Val Phe Ile Arg Ala Ala Glu Glu Glu 305 310 315 320 Asn Leu Ile Ile Pro Leu Thr Lys His Leu Phe Glu Leu Ile Ile Gln 325 330 335 Asp Val Gln Ser Trp Lys Val Lys Lys Pro Phe His Leu Gly Ile Asn 340 345 350 Ile Ala Ala Glu His Leu Ala His Pro Asp Phe Val Ala Asp Val Leu 355 360 365 His Ile Lys Asn Ala Ile Ser Asp Lys Phe Asn Ile Val Leu Glu Ile 370 375 380 Thr Glu Arg Asn Leu Val Glu Asp Thr Asp His Ala Leu Gln Lys Ile 385 390 395 400 Asn Glu Leu Arg Ser His Gly Cys Glu Phe Ala Val Asp Asp Phe Gly 405 410 415 Thr Gly Tyr Cys Ser Leu Gly Leu Leu Gln Lys Leu Ser Val Asp Tyr 420 425 430 Leu Lys Ile Asp Lys Ser Phe Ile Asp Thr Leu Thr Thr Ala Glu Asp 435 440 445 Glu Thr Pro Val Leu Asp Ile Ile Ile Lys Leu Ser Asn Arg Leu Asn 450 455 460 Leu Ile Thr Ile Ala Glu Gly Val Ser Thr Ser His Gln Ala Glu Tyr 465 470 475 480 Leu Ile His Asn Asn Val Thr Leu Val Gln Gly Tyr Leu Tyr Ala Lys 485 490 495 Pro Met Lys Ala Thr Glu Phe Tyr Gln Trp Tyr Val Asn Arg * 500 505 510 <210> 1031 <211> 164 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1799..2290) <400> 1031 Met Thr Gln Arg Tyr Phe Leu Phe Ala Gly Ile Ile Leu Cys Ala Phe 1 5 10 15 Ile Ala Ala Ile Leu Ser His Ile Ala Phe His His Ala Asn Glu Pro 20 25 30 Ala Glu Gln Asn Ile Ser Cys Asn Ala His Val Ile Asn Phe Thr Asp 35 40 45 His Thr Lys Met Asp Gln Tyr Phe Ser Leu Asn Met Ile Ser Glu Asn 50 55 60 Asn Thr Gly Asn Met Tyr Leu Thr Gly Ala Tyr Thr Val Asp Gly Lys 65 70 75 80 Lys Ile Gly Phe Ile Arg Arg Tyr Val Ser Phe Thr Tyr Lys Lys Phe 85 90 95 Arg Asp Thr Val Tyr Phe Thr Thr Val Lys Ile Gln Lys Ile Gln Lys 100 105 110 Asp Asp Asn Ile Ser Asp Glu Ile Leu Glu Asn Ile Thr Ser Asp Phe 115 120 125 Phe Ile Lys Val Asp Thr Ser Ile Asn Phe Tyr Val Thr Arg Gln Asn 130 135 140 Asp Tyr Asn Tyr Val Phe Ser Thr Gly Arg Thr Pro Arg Phe Ile Cys 145 150 155 160 Ile Ser His * <210> 1032 <211> 271 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2295..3107) <400> 1032 Met Ile Tyr Ile Ile Asn Asp Glu Val Arg Phe Asn Ser Ser Ser Asn 1 5 10 15 Lys Leu Thr Ser Leu Leu Thr Ser Glu Glu Val Ile Leu Thr Tyr Pro 20 25 30 Ala Gly Lys Cys Leu Lys Leu Leu Leu Asp Asn Ala Tyr Ser Val Val 35 40 45 Ser His Asn Gln Phe Phe Glu Lys Val Trp Ser Asp Ser Ser Ala Asp 50 55 60 Val Ala Thr Asn Thr Leu Tyr Gln Asn Ile Ser Met Ile Arg Arg Ser 65 70 75 80 Phe Arg Glu Ile Ser Ser Ala Thr Ile Phe Asn Asp Val Ile Arg Thr 85 90 95 Val Pro Arg Lys Gly Phe Lys Ile Asn Glu Glu Ile Ser Ile Thr Val 100 105 110 Leu Asp Asn Asn His Asn Glu Asn Glu Ser Val Glu Ser Glu Glu Asn 115 120 125 Gly Thr His Thr Glu Asn Ile Asn Lys Asn His Ile Ala Lys Gly Ile 130 135 140 Phe Thr Thr Lys Asn Thr Leu Leu Ile Val Cys Phe Phe Ala Ala Trp 145 150 155 160 Gly Ile Val Tyr Ile Ser Ser Tyr Phe Phe Asp Met Ala Phe Gln Ser 165 170 175 Lys Ser His Thr Ile Lys Lys Ile Asp Ala Phe Ser Asn Tyr Ala Gln 180 185 190 His Pro Thr Gln Glu Gly Cys Ser Tyr Phe Tyr Asp Asn Lys Tyr Phe 195 200 205 Asn Ser Val Asp Met Leu Ser Pro Ile Ile Glu Lys Leu Gln Lys Met 210 215 220 Glu Ile Asn Cys Lys Ile His Pro Tyr Ile Tyr Ile Ala Thr Asn Asp 225 230 235 240 Ser Met Ser Gly Phe Tyr Ala Phe Thr Cys Ser Gln Met Leu Asn Ser 245 250 255 Glu Ser Pro Asn Asn Cys Asn Ser Leu Tyr Tyr Lys Ala Glu * 260 265 270 <210> 1033 <211> 264 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3786..4577) <400> 1033 Met Cys Asp Met Ser Phe Ser Ile Glu Asp Phe Ser Leu Asp Phe Phe 1 5 10 15 Ser Leu His Asn Lys Val Ala Ile Val Thr Gly Ala Ala Gly Glu Leu 20 25 30 Gly Arg Gly Leu Cys Ser Ala Leu Ala Lys Ala Gly Ala Asn Leu Leu 35 40 45 Leu Val Asp Ile Lys Glu Pro Asp Asn Arg Tyr Leu Lys His Leu Thr 50 55 60 His Glu Gly Val Glu Val Glu Phe Met Thr Ile Asp Ile Thr Lys Pro 65 70 75 80 Asp Ala Ser Cys Thr Ile Ile Asn Arg Cys Leu Glu Arg Phe Gly Gln 85 90 95 Leu Asp Ile Leu Val Asn Asn Ala Gly Val Cys Asn Ile Asn Arg Pro 100 105 110 Ile Asp Phe Asn Arg Asn Asp Trp Asp Pro Met Ile Asn Leu Asn Leu 115 120 125 Asn Ala Ala Phe Asp Met Ser Gln Ala Ala Leu Asn Ile Phe Val Pro 130 135 140 Gln Arg Lys Gly Lys Ile Ile Asn Met Cys Ser Val Leu Ser Phe His 145 150 155 160 Gly Gly Arg Trp Ser Pro Gly Tyr Ala Ala Thr Lys His Ala Leu Ala 165 170 175 Gly Leu Thr Lys Ala Tyr Ala Asp Asp Phe Ala Glu Tyr Asn Ile Gln 180 185 190 Ile Asn Gly Ile Ala Pro Gly Tyr Tyr Val Ser Glu Met Thr Ala Ile 195 200 205 Ile Tyr Asn Asn Pro Lys Ile Lys Glu Leu Ile Lys Gly Arg Ile Pro 210 215 220 Ala Gln Arg Trp Gly Arg Ala Gln Asp Leu Met Gly Ala Met Val Phe 225 230 235 240 Leu Ala Ser Ala Ala Ser Asp Tyr Val Asn Gly Gln Leu Leu Val Ile 245 250 255 Asp Gly Gly Tyr Ser Ile Arg * 260 <210> 1034 <211> 210 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4723..5352) <400> 1034 Met Pro Ala Ser Ser Arg Ile Ile Tyr Arg Asp Gly Asp Arg Glu Lys 1 5 10 15 Thr Leu Met Leu Val Asn Thr Asn Asp Tyr Pro Val Leu Val Gln Ser 20 25 30 Trp Val Asp Asn Gly Glu Gly Ser Pro Glu Ala Ala Ser Pro Pro Phe 35 40 45 Val Val Leu Pro Pro Val Phe Arg Leu Ala Ala Arg Arg Thr Gln Gly 50 55 60 Leu Arg Ile Ile Tyr Asn His Asp Pro Leu Pro Gln Asp Arg Glu Ser 65 70 75 80 Ala Phe Trp Leu Asn Leu Tyr Glu Met Pro Pro Glu Thr Pro His Gln 85 90 95 Asp Pro Thr His Leu Thr Leu Ala Met Asn Thr Gln Leu Lys Ile Phe 100 105 110 Tyr Arg Pro Lys Ser Val Thr Met Thr Pro Gln Glu Ala Met Arg Lys 115 120 125 Ile Ser Trp His Leu Gly Asn Asp Gly Ser Ser Ser Tyr Ile Glu Leu 130 135 140 Asn Asn Pro Thr Pro Leu Asn Ile Ser Phe Thr Ser Ile Ser Ile Gly 145 150 155 160 Ala Thr Lys Val Gln Gln Glu Ser Asp Met Met Ile Lys Pro Phe Ser 165 170 175 Gln Arg Arg Tyr Trp Leu Ala Ser Asn Asn Val Ser Gly Val Val Ala 180 185 190 Ala Thr Tyr Leu Asp Asp Asn Gly Ala Gln Ile Lys Gln Gln Leu Ala 195 200 205 Gln * <210> 1035 <211> 445 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5409..6743) <400> 1035 Met Ser Lys Ser Thr Phe Leu His Ile Leu Ile Ser Ser Ile Ile Leu 1 5 10 15 Val Ala Leu Ile Gln Ser Ser Ala Trp Ala Asn Cys Thr Asn Thr Gln 20 25 30 Ile Gly Gln Thr Glu Asp Gly Arg Thr Ala Leu Ile Glu Phe Gly Lys 35 40 45 Ile Asn Met Thr Asp Thr Tyr Phe Ala Pro Ala Gly Ser Leu Leu Ala 50 55 60 Thr Thr Val Val Pro Pro Thr Asn Tyr Thr Ser Gly Gly Ala Thr Gly 65 70 75 80 Ser Ser Val Leu Trp Glu Cys Asp Ala Thr Asp Leu Pro Asn Ile Tyr 85 90 95 Phe Leu Val Ala Thr Asn Gly Asp Asp Arg Val Gly Gly Phe Tyr Asp 100 105 110 Ala Gly Gly Pro Asp Gly Leu Ser Asp Val Tyr Ala Thr Trp Phe Ala 115 120 125 Phe Val Gly Leu Lys Gln Thr Met Ala Gly Val Thr Leu Gly Arg Tyr 130 135 140 Trp Lys Lys Val Pro Ile Thr Ser Tyr Ala Thr Gln Gly Thr Lys Ile 145 150 155 160 Gln Ile Arg Leu Gln Asp Ile Pro Pro Leu His Ala Glu Leu Tyr Arg 165 170 175 Ile Ser Thr Leu Pro Asp Thr Ser Ala Thr Thr Ser Trp Cys Gly Asn 180 185 190 Asn Asn Thr Asp Ser Ser Gly Val Gly Phe Ala Lys Pro Ser Gly Thr 195 200 205 Ile Tyr Asn Cys Val Gln Pro Asn Ala Tyr Ile Gln Leu Ser Gly Thr 210 215 220 Ser Gly Ile Leu Phe Gly His Asp Glu Pro Gly Glu Asp Ser Ser Val 225 230 235 240 His Trp Asp Phe Trp Gly Ala Asp Asn Gly Phe Gly Tyr Gly Met Arg 245 250 255 Ser Ala Asn Arg Leu Tyr Asn Asn Ala Thr Cys Val Ala Arg Ser Ala 260 265 270 Thr Pro Leu Val Leu Leu Pro Thr Ile Ala Glu Ala Gln Leu Asn Ala 275 280 285 Gly Met Glu Ser Thr Gly Asn Phe Asn Val Arg Val Glu Cys Ser Asn 290 295 300 Ser Val Gln Ser Gly Ile Ser Asp Thr Gln Thr Ala Leu Gly Ile Gln 305 310 315 320 Val Ser Glu Gly Ala Tyr Thr Ala Ala Gln Lys Leu Gly Ile Ile Asn 325 330 335 Ser Asn Gly Gly Val Ser Ala Leu Val Ser Asp Asn Tyr Asp Ala Ala 340 345 350 Glu Met Ala Lys Gly Val Gly Ile Tyr Ile Ser Asn Ser Ala His Pro 355 360 365 Asp Thr Ala Met Thr Leu Val Gly Gln Pro Gly Ile Ala Lys Leu Thr 370 375 380 Pro Gly Gly Asn Ala Ala Gly Trp Tyr Pro Val Phe Glu Gly Ala Thr 385 390 395 400 Leu Glu Gly Ala Thr His Pro Gly Tyr Ser Ser Tyr Ser Tyr Ser Phe 405 410 415 Ile Ala Arg Leu Lys Lys Leu Pro Asn Gln Thr Val Ser Ala Gly Lys 420 425 430 Val Arg Ala Thr Ala Tyr Ile Leu Val Lys Met Gln * 435 440 <210> 1036 <211> 841 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6759..9281) <400> 1036 Met Asn Lys Ser Val Val Ser Ile Ser Ala Ala Met Leu Val Leu Leu 1 5 10 15 Cys Gln Pro Val Met Gly Ser Glu Ile Ser Pro Ala Thr Pro Ser Asp 20 25 30 Glu Asp Asn Tyr Thr Phe Asp Pro Gln Leu Phe Arg Gly Ser Arg Phe 35 40 45 Ser Gln Ser Ser Leu Ala Lys Leu Thr Thr Arg Glu Ser Val Ala Pro 50 55 60 Gly Asn Tyr Lys Met Asp Ile Tyr Thr Asn Asn Lys Leu Ser Gly Ser 65 70 75 80 Trp Asn Val Thr Phe Lys Glu Ala Ala Asp Gly Arg Val Leu Pro Cys 85 90 95 Leu Thr Pro Glu Val Ala Asp Ala Ile Gly Leu Lys Thr Gly Glu Asp 100 105 110 Lys Gly Glu Lys Asp Pro Val Cys Thr Phe Ala Lys Glu Leu Ala Pro 115 120 125 Gly Ile Thr Ser Gln Thr Gln Leu Ser Gln Leu Arg Leu Asp Leu Ser 130 135 140 Val Pro Gln Ser Gln Leu Ile Ser Arg Pro Arg Gly Tyr Val Pro Pro 145 150 155 160 Ser Glu Leu Asp Thr Gly Ala Ser Leu Ala Phe Met Asn Tyr Ile Ala 165 170 175 Asn Tyr Tyr Asn Val Ala Tyr Ser Gly Gln Asn Ala His Ser Gln Arg 180 185 190 Ser Leu Trp Ala Ser Phe Asn Gly Gly Ile Asn Leu Gly Ala Trp Gln 195 200 205 Tyr Arg Gln Leu Ser Asn Met Thr Trp Asp Asn Asp Lys Gly Asn Gln 210 215 220 Trp Asn Asn Ile Arg Ser Tyr Leu Gln Arg Pro Leu Pro Ala Ile Asn 225 230 235 240 Ser Gln Leu Met Met Gly Gln Leu Ile Thr Ser Gly Arg Phe Phe Ser 245 250 255 Gly Leu Ser Tyr His Gly Val Ser Leu Ala Thr Asp Glu Arg Met Leu 260 265 270 Pro Asp Ser Met Arg Gly Tyr Ala Pro Thr Ile Arg Gly Val Ala Ala 275 280 285 Thr Asn Ala Arg Val Ser Val Met Gln Asn Gly His Glu Ile Tyr Gln 290 295 300 Thr Thr Val Ala Pro Gly Pro Phe Glu Ile Asn Asp Leu Tyr Pro Thr 305 310 315 320 Ser Tyr Ser Gly Asp Leu Asp Val Thr Val Thr Glu Ala Asn Gly Ala 325 330 335 Val Ser Arg Phe Ser Val Pro Phe Ser Ala Val Pro Glu Ser Met Arg 340 345 350 Pro Gly Thr Ser Arg Tyr Asn Val Glu Val Gly Lys Thr Gln Asp Ser 355 360 365 Gly Asp Asp Ser Met Phe Gly Asp Leu Thr Trp Gln His Gly Met Thr 370 375 380 Asn Thr Leu Thr Phe Asn Ser Gly Ser Arg Ile Ala Asp Gly Tyr Gln 385 390 395 400 Ala Leu Met Leu Gly Gly Val Tyr Gly Ser Ser Leu Gly Ala Phe Gly 405 410 415 Ala Asn Leu Thr Trp Ser His Ala Arg Val Pro Glu Ser Glu Ala Gln 420 425 430 Ser Gly Trp Met Ser Gln Leu Thr Trp Ser Lys Thr Phe Gln Pro Thr 435 440 445 Ser Thr Thr Val Ser Leu Ala Gly Tyr Arg Tyr Ser Thr Ser Gly Tyr 450 455 460 Arg Asp Leu Ala Asp Val Leu Gly Glu Arg His Ala Ala Ser Asn Lys 465 470 475 480 Gln Ser Trp Asp Ser Ser Gln Trp Arg Gln Gln Ser Arg Phe Asp Leu 485 490 495 Thr Leu Ser Gln Ser Leu Ala Asn Tyr Gly Asn Leu Phe Val Ser Gly 500 505 510 Ser Thr Gln Asn Tyr Arg Gly Gly Lys Ser Arg Asp Thr Gln Leu Gln 515 520 525 Leu Gly Tyr Ser Asn Ser Phe Ser His Gly Ile Ser Met Asn Leu Ser 530 535 540 Val Gly Arg Gln Arg Met Gly Gly Tyr Lys Asp Asn Ser Asp Asp Met 545 550 555 560 Gln Thr Val Thr Ser Leu Ser Phe Ser Phe Pro Leu Gly Gly Asn Gly 565 570 575 Pro Arg Val Pro Ser Leu Ser Asn Ser Trp Thr His Ser Thr Asp Gly 580 585 590 Ser Ser Gln Leu Gln Ser Ser Leu Thr Gly Met Leu Asp Glu Ala Gln 595 600 605 Thr Thr Asn Tyr Ser Leu Asn Val Met Arg Asp Gln Gln Tyr Lys Gln 610 615 620 Thr Thr Leu Ser Gly Asn Met Gln Lys Arg Phe Ser Gln Thr Thr Val 625 630 635 640 Gly Leu Asn Ala Ser Lys Gly Gln Asp Tyr Trp Gln Ala Ser Gly Asn 645 650 655 Val Gln Gly Ala Met Ala Val His Gly Gly Gly Ile Thr Phe Gly Pro 660 665 670 Tyr Leu Gly Glu Thr Phe Ala Leu Val Glu Ala Lys Gly Ala Glu Gly 675 680 685 Ala Lys Val Tyr Asn Ser Ser Gln Leu Glu Ile Asn Asp Ser Gly Tyr 690 695 700 Ala Leu Val Pro Ala Val Thr Pro Tyr Arg Tyr Asn Arg Ile Ser Leu 705 710 715 720 Asp Pro Gln Gly Met Asp Gly Asp Ala Glu Leu Val Asp Ser Glu Arg 725 730 735 Gln Val Ala Pro Val Ala Gly Ala Ala Val Lys Val Ile Phe Arg Thr 740 745 750 Arg Pro Gly Lys Ala Leu Leu Ile Lys Ser Arg Met Ala Asp Gly Ser 755 760 765 Glu Leu Pro Met Gly Ala Asp Val Leu Asp Glu Asn Asn Thr Val Val 770 775 780 Gly Ile Ala Gly Gln Gly Gly Gln Ile Tyr Leu Arg Thr Glu Gln Thr 785 790 795 800 Lys Gly His Leu Ser Val Arg Trp Gly Glu Gly Ala Asn Asp Ser Cys 805 810 815 Gln Leu Pro Phe Asp Ile Ser Gly Lys Asp Ser Asn Ser Pro Ile Ile 820 825 830 Arg Leu Asn Glu Thr Cys Gln Ser * 835 840 <210> 1037 <211> 234 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9334..10035) <400> 1037 Met Asn Ile Phe Ala Tyr Leu Leu Val Leu Val Phe Ser Met Ser Met 1 5 10 15 Ser Ser Ser Ala Phe Ala Ser Val Val Met Thr Gly Thr Arg Ile Ile 20 25 30 Phe Pro Gly Asp Ala Lys Glu Lys Thr Ile Gln Leu Arg Asn Thr Ser 35 40 45 Asp Gln Pro Tyr Ile Ile Asn Ile His Val Glu Asp Glu Arg Gly Ser 50 55 60 Asp Lys Asn Val Pro Phe Met Pro Thr Pro Gln Thr Phe Arg Met Glu 65 70 75 80 Ala Ala Ala Gly Gln Ala Leu Arg Leu Leu Tyr Thr Gly Asn Asn Leu 85 90 95 Pro Gln Asp Arg Glu Ser Val Phe Trp Phe Ser Phe Ser Gln Leu Pro 100 105 110 Tyr Leu Asn Lys Asn Asp Lys Ser Gln Asn Gln Leu Ile Leu Ala Leu 115 120 125 Thr Asn Arg Val Lys Ile Phe Tyr Arg Pro Ser Ser Ile Val Gly Lys 130 135 140 Ser Ser Asp Ala Pro Lys Asn Leu Thr Tyr Gln Val Lys Gln Asn Arg 145 150 155 160 Ile Glu Val Thr Asn Pro Thr Gly Tyr Tyr Val Thr Ile Arg Ala Ala 165 170 175 Glu Leu Leu Asn Asn Gly Lys Lys Val Pro Leu Ala Asn Ser Val Met 180 185 190 Ile Ala Pro Gln Ser Thr Thr Glu Trp Thr Leu Pro Ser Gly Ile Ser 195 200 205 Val Ala Pro Gly Ala Gln Ile His Leu Val Thr Val Asn Asp Tyr Gly 210 215 220 Val Asn Val Thr Ser Glu His Ala Leu * 225 230 <210> 1038 <211> 187 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10121..10681) <400> 1038 Met Phe Ser Thr Phe Lys Lys Ala Ala Leu Leu Ala Ala Ile Ala Leu 1 5 10 15 Pro Phe Ser Thr Met Ala Ala Pro Thr Val Thr Phe Gln Gly Glu Val 20 25 30 Thr Asp Gln Thr Cys Ser Val Asn Ile Asn Gly Gln Thr Asn Ser Val 35 40 45 Val Leu Met Pro Thr Val Ala Met Ala Asp Phe Gly Ala Thr Leu Ala 50 55 60 Asp Gly Gln Ser Ala Gly Gln Thr Pro Phe Thr Val Ser Val Ser Asn 65 70 75 80 Cys Gln Ala Pro Thr Gly Ala Asp Gln Ala Ile Asn Thr Thr Phe Leu 85 90 95 Gly Tyr Asp Val Asp Ala Ser Thr Gly Val Met Gly Asn Arg Asp Thr 100 105 110 Ser Ser Asp Ala Ala Lys Gly Phe Gly Ile Gln Leu Met Asp Ser Ser 115 120 125 Thr Ser Gly Asn Pro Val Thr Leu Ala Gly Ala Thr Asn Val Pro Gly 130 135 140 Leu Thr Leu Lys Val Gly Asp Thr Glu Ala Ser Tyr Asp Phe Gly Ala 145 150 155 160 Arg Tyr Phe Val Ile Asp Ser Ala Ala Ala Thr Ala Gly Lys Ile Thr 165 170 175 Ala Val Ala Glu Tyr Thr Leu Ser Tyr Leu * 180 185 <210> 1039 <211> 208 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10724..11347) <400> 1039 Met Asn Lys Asn Leu Leu Thr Arg Val Ile Ile Ile Ser Asp Asp Leu 1 5 10 15 Tyr Tyr Leu Gln Gly Leu Ser Ala Lys Leu Gly His His Tyr Arg Phe 20 25 30 Phe Ile Glu Cys Phe Phe Cys Ser Gln Asn Ala Cys Asn Asn Asp Leu 35 40 45 Ser Thr Leu Arg Phe Asp Asn Arg Phe Thr Lys Asn Val Leu Leu Val 50 55 60 Ala Val Asp Asp Val Ser Ile Leu Ala Lys Leu Pro Asp Leu Ala Arg 65 70 75 80 Phe Leu Met Ile Val Ser Leu Arg Lys Met Lys Asn Arg Asn Ile Phe 85 90 95 Phe Ser Leu Ser Glu Gln Thr Phe Ile Ser Arg Tyr Ile Lys Leu Asn 100 105 110 Lys Leu Ile Thr Leu Ile Lys Ser Thr Asp Lys Asp Gln Gln Val Arg 115 120 125 Gln Val Thr Leu Thr Arg Tyr Glu Trp Asp Ile Tyr Tyr Leu Tyr Phe 130 135 140 Lys Ile Asp Asn Lys Arg Ile Leu His Thr Leu Leu Lys Lys Asp Val 145 150 155 160 Lys Tyr Ile Ser His Tyr Lys Ile Ser Val Phe Asn Lys Phe Glu Ile 165 170 175 Ala Cys Asp Ser Asp Gly Phe Tyr Ile Phe Lys Ala Leu Ile Gln Leu 180 185 190 Arg Arg Phe Thr Gly Phe Lys Asn Val Arg Leu Tyr Gln Leu His * 195 200 205 <210> 1040 <211> 1269 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12744..16550) <400> 1040 Met Ile Asn Leu Ser Lys Glu Ala Thr Val Gly Lys Ala Leu Thr Pro 1 5 10 15 Ile Ala Ile Leu Met Met Leu Ser Phe Pro Val Ala Ser Gln Ala Ala 20 25 30 Gly Leu Val Ile Lys Asn Gly Thr Val Tyr Asn Ala Asn Gly Val Pro 35 40 45 Val Val Asp Ile Asn Lys Pro Asn Gly Ser Gly Leu Ser His Asn Ile 50 55 60 Trp Asp Asn Leu Asn Val Asp Lys Asn Gly Val Val Phe Asn Asn Ser 65 70 75 80 Ala Asn Glu Ser Ser Thr Ser Leu Ala Gly Asn Ile Gln Gly Asn Ser 85 90 95 Asn Leu Thr Ser Gly Ser Ala Lys Val Ile Leu Asn Glu Val Thr Ser 100 105 110 Lys Asn Pro Ser Thr Ile Asn Gly Met Met Glu Val Ala Gly Asp Lys 115 120 125 Ala Asp Leu Ile Ile Ala Asn Pro Asn Gly Ile Thr Val Asn Gly Gly 130 135 140 Gly Ser Ile Asn Thr Gly Lys Leu Thr Leu Thr Thr Gly Thr Pro Asp 145 150 155 160 Ile Gln Asp Asp Lys Leu Ala Gly Tyr Ser Val Asn Gly Gly Thr Ile 165 170 175 Thr Leu Gly Lys Leu Asp Asn Ala Ser Pro Thr Glu Ile Leu Ser Arg 180 185 190 Asn Val Val Val Asn Gly Lys Val Ser Ala Asp Glu Leu Asn Val Val 195 200 205 Ala Gly Asn Asn Tyr Val Asn Ala Ala Gly Gln Val Thr Gly Ser Val 210 215 220 Ser Ala Thr Gly Ser Arg Asn Gly Tyr Ser Val Asp Val Ala Lys Leu 225 230 235 240 Gly Gly Met Tyr Ala Asn Lys Ile Ser Leu Val Ser Thr Glu Lys Gly 245 250 255 Val Gly Val Arg Asn Leu Gly Val Ile Ala Gly Gly Val Asn Gly Val 260 265 270 Ser Ile Asp Ser Lys Gly Asn Leu Leu Asn Ser Asn Ala Gln Ile Gln 275 280 285 Ser Ala Ser Thr Ile Asn Leu Thr Thr Asn Gly Thr Leu Asp Asn Thr 290 295 300 Thr Gly Thr Val Thr Ser Val Gly Thr Ile Ser Leu Asn Thr Asn Lys 305 310 315 320 Asn Thr Ile Val Asn Thr Arg Ala Gly Asn Ile Ser Thr Met Gly Asp 325 330 335 Ile Tyr Val Asn Ser Gly Thr Ile Asp Asn Thr Asn Gly Lys Leu Ala 340 345 350 Ala Ala Gly Met Leu Ala Val Asp Thr Asn Asn Ala Thr Leu Ile Asn 355 360 365 Ser Gly Lys Gly Ser Ser Val Gly Ile Glu Ala Gly Leu Val Ala Leu 370 375 380 Lys Thr Gly Thr Leu Asn Asn Ser Asn Gly Gln Ile Arg Gly Gly Tyr 385 390 395 400 Val Gly Leu Glu Ser Ala Ala Leu Asn Asn Asn Asn Gly Asp Ile Gln 405 410 415 Thr Thr Gly Asp Ile Ala Ile Ile Ser Asn Gly Asn Val Asp Asn Asn 420 425 430 Lys Gly Leu Ile Arg Ser Ser Thr Gly His Ile Val Ile Gly Ala Ala 435 440 445 Gly Ser Val Asn Asn Gly Ser Thr Lys Thr Ala Asp Thr Gly Ser Ser 450 455 460 Asp Ser Leu Gly Ile Ile Ala Asp Thr Gly Val Glu Ile Gly Ala Asn 465 470 475 480 Asn Ile Asn Asn Asn Gly Gly Gln Ile Ala Ser Asn Gly Asn Val Ser 485 490 495 Leu Ser Ser Tyr Ser Thr Ile Asp Asp Tyr Ala Gly Lys Ile Leu Ser 500 505 510 Asn Ser Lys Val Ile Ile Lys Gly Ser Ser Leu Arg Asn Asp Thr Gly 515 520 525 Gly Ile Ser Gly Lys Gln Gly Ile Glu Val Ala Val Gly Gly Ser Leu 530 535 540 Thr Asn Asn Ile Gly Val Ile Ser Ser Glu Glu Gly Asp Ile Ser Leu 545 550 555 560 Leu Ala Asn Ser Val Asp Asn His Gly Gly Phe Met Met Gly Gln Asn 565 570 575 Ile Thr Met Glu Ser Met Ser Gly Val Asn Asn Asn Thr Ala Leu Ile 580 585 590 Val Ala Ser Lys Lys Leu Lys Ile Asn Ala Arg Gly Ser Ile Glu Asn 595 600 605 Arg Asp Gly Asn Asn Phe Gly Asn Ala Tyr Gly Leu Tyr Phe Gly Met 610 615 620 Pro Gln Gln Thr Gly Gly Met Val Gly Lys Glu Gly Ile Glu Leu Ser 625 630 635 640 Gly Gln Asn Ile Tyr Asn Asn Asn Ser Arg Leu Ile Ala Glu Asp Gly 645 650 655 Pro Leu Thr Leu Gln Ala Gln Asn Thr Phe Asp Asn Thr Arg Ala Leu 660 665 670 Val Thr Ser Gly Ala Asp Ala Ser Ile Gln Val Gly Gly Thr Tyr Tyr 675 680 685 Asn Asn Tyr Ala Thr Thr Trp Ser Ala Gly Asn Leu Asp Ile Asp Ala 690 695 700 Thr Thr Leu Gln Asn Ser Ser Ser Gly Thr Met Ile Asp Asn Asn Ala 705 710 715 720 Thr Gly Phe Ile Ala Ser Asp Lys Asn Leu Ser Leu Glu Val Val Asn 725 730 735 Ser Leu Thr Asn Tyr Gly Trp Ile Ser Gly Lys Gly Asp Val Asp Val 740 745 750 Thr Val Asn Asn Gly Asn Leu Tyr Asn Arg Asn Thr Ile Ala Ala Glu 755 760 765 Lys Gly Leu Asp Ile Ala Ala Leu Asn Gly Ile Glu Asn Trp Lys Asp 770 775 780 Ile Ser Ala Gly Gly Asp Leu Thr Met Asn Thr Asn Arg His Val Thr 785 790 795 800 Asn Asn Ser Asn Ser Asn Met Val Gly Gln Asn Ile Val Ile Asn Ala 805 810 815 Val Asn Asp Ile Asn Asn Arg Gly Asn Ile Val Ser Asp Ala Asp Leu 820 825 830 Asn Val Thr Thr Lys Gly Asn Leu Tyr Asn Tyr Leu Tyr Met Val Gly 835 840 845 Tyr Gly Asp Ile Ala Leu Ser Ala Asn Ser Val Ala Asn Asn Asn Ala 850 855 860 Thr Ile Glu Ala Thr Gly Asp Leu Ile Ile Asp Ser Lys Gly Asn Val 865 870 875 880 Gly Asn Asn Arg Gly Asn Leu His Ala Leu Asn Gly Val Leu Ser Val 885 890 895 Lys Gly Asn Asn Leu Asn Asn Asp Asn Gly Glu Ile Arg Gly Tyr Gly 900 905 910 Asp Val Thr Leu Ala Leu Thr Gly Asn Tyr Asp Ser Tyr Lys Gly Ser 915 920 925 Leu Thr Ser Glu Thr Gly Asp Val Thr Leu Thr Ala Asn Ile Val Asp 930 935 940 Asn Ala Tyr Gly Leu Ile Ala Gly Glu Asn Val Ser Val Asp Ala Lys 945 950 955 960 Ser Thr Ile Tyr Asn Asn Thr Ala Leu Ile Ala Ala Asn Lys Lys Leu 965 970 975 Val Ile Asn Ala Gly Gly Asn Leu Glu Asn Arg Asp Gly Asn Asn Phe 980 985 990 Leu Arg Asn Asn Gly Ala Leu Phe Gly Ile Thr Asp Asn Val Gly Gly 995 1000 1005 Ile Val Gly Lys Glu Gly Val Thr Leu Ser Ala Gln Asn Val Tyr Asn 1010 1015 1020 Asn Asn Ser Ser Ile Ile Ala Glu Asn Gly Pro Leu Asn Leu Leu Ser 1025 1030 1035 1040 Arg Gly Thr Leu Asp Asn Thr Arg Ala Leu Leu Ser Ser Gly Ala Asp 1045 1050 1055 Ala Ile Ile Arg Ala Ala Gly Thr Phe Tyr Asn Asn Tyr Ala Thr Thr 1060 1065 1070 Tyr Ser Ala Gly Asn Leu Asp Val Tyr Ala Ala Ser Leu Asn Asn Ala 1075 1080 1085 Ser Asp Gly Arg Leu Glu Asp Asn Thr Ala Thr Gly Val Ile Ala Ser 1090 1095 1100 Asp Lys Asn Leu Asp Leu Ser Val Asp Asn Ser Val Thr Asn Tyr Gly 1105 1110 1115 1120 Trp Ile Ser Gly Lys Gly Asp Val His Phe Asn Val Leu Lys Gly Thr 1125 1130 1135 Leu Tyr Asn Arg Asn Ala Ile Ala Ala Asp Asn Ala Leu Thr Ile Asn 1140 1145 1150 Ala Leu Asn Gly Val Glu Asn Phe Lys Asp Ile Val Ala Gly Thr Ala 1155 1160 1165 Leu Thr Ile Asp Thr Gln Lys Tyr Val Thr Asn Asn Ser Asn Ser Asn 1170 1175 1180 Met Leu Gly Gln Thr Ile Ala Ile Asn Ala Val Asn Asp Ile Asn Asn 1185 1190 1195 1200 Arg Gly Asn Ile Val Gly Asp Tyr Ser Leu Gly Val Lys Thr Thr Gly 1205 1210 1215 Asn Ile Tyr Asn Tyr Leu Asn Met Leu Ser Tyr Gly Val Ala Gly Val 1220 1225 1230 Ser Ala Asn Lys Val Thr Asn Ser Gly Lys Asp Ala Val Leu Gly Gly 1235 1240 1245 Phe Tyr Gly Leu Ala Leu Glu Ala Asn Glu Thr Asp Asn Thr Gly Thr 1250 1255 1260 Ile Val Gly Met * 1265 <210> 1041 <211> 540 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16639..18258) <400> 1041 Met Gln Leu Arg Phe Asn Phe Gly Leu Leu Leu Ile Leu Cys Cys Phe 1 5 10 15 Gln Val Ala Ala Lys Asp Ser Leu Asp Asn Leu Ile Lys Gln Gln Lys 20 25 30 Asn Ala Asp Glu Ser Thr Leu Arg Ala His Lys Leu Glu Lys Lys Asp 35 40 45 Val Tyr Ser Asn Ala Gln Arg Asn Ala Phe Thr Leu Gly Asp Leu Pro 50 55 60 Gln Glu Lys Asn Cys Phe Ile Ile Asn Arg Ile Glu Leu Glu Asp Asn 65 70 75 80 Phe Leu Gly Gly Gln Leu Ile Ser Glu Val Gln Lys Ala Ile Ala Gly 85 90 95 Arg Cys Val Gly Ser Ala Gly Val Gln Lys Ile Ala Ala Ala Leu Gln 100 105 110 Asp Tyr Tyr Ile Asn Ala Gly Tyr Ile Thr Thr Arg Ile Ser Ile Pro 115 120 125 Ser Gln Asp Ile Ser Lys Gly Lys Leu Arg Phe Gln Val Asn Ala Gly 130 135 140 Lys Ile Glu Lys Thr Ile Val Glu Gly Asn Asp Ile Ser Glu Trp Met 145 150 155 160 Leu Pro Phe Gln Arg Asn Asp Ile Leu Asn Ile Arg Asp Ile Glu Gln 165 170 175 Gly Leu Glu Asn Leu Gln Arg Val Pro Asp Val Asp Val Lys Ile Asn 180 185 190 Ile Glu Pro Gly Thr Arg Asp Gly Tyr Ser Ile Val His Ile Asp Thr 195 200 205 His Arg Gly Lys Asn Trp Ser Val Arg Ala Ser Tyr Asn Asn Trp Gly 210 215 220 Asp Glu Glu Thr Gly Arg Tyr Gln Thr Thr Ser Val Gly Tyr Leu Phe 225 230 235 240 Asn Pro Ala Lys Met Gly Asp Leu Phe Tyr Leu Ala Gly Thr Arg Ser 245 250 255 Thr Thr Gly Gln Tyr Glu Asn Val Ser Ser Tyr Tyr Ser Ile Pro Val 260 265 270 Gly Tyr Trp Glu Tyr Gly Phe Phe Tyr Ser Lys Ser Lys Ser Gln Gln 275 280 285 Val Ile Pro Leu Ser Tyr Ile Ser Leu Asp Tyr Val Gly Ile Ser Glu 290 295 300 Tyr Leu Ser Ala Lys Ala Thr His Thr Val Tyr Arg Asp Lys Thr Lys 305 310 315 320 Lys Phe Ala Gly Ser Ala Glu Leu Ile Arg Arg Lys Ser Asn Tyr Thr 325 330 335 Leu Asn Gly Glu Glu Leu Thr Leu Gln Ala Arg Asp Met Gly Asn Ile 340 345 350 Lys Leu Gly Leu Asn Tyr Lys Gln Gln Leu Pro Gly Ala Phe Trp Asp 355 360 365 Ser Thr Leu Ser Trp Gln Arg Phe Leu Thr Trp Phe Gly Gly Glu Lys 370 375 380 Thr Pro Asp Met Gln Tyr Gly Asp Val Ser Pro Val Ser Asn Ile Phe 385 390 395 400 Asn Phe Glu Gly Asn Tyr Thr Arg Gln Ile Glu Asn Gly Tyr Tyr Asn 405 410 415 Thr Ala Phe Phe Ala Gln Tyr Ala Pro Arg Glu Leu Thr Leu Gln Asp 420 425 430 Lys Ile Thr Val Gly Asp Arg Trp Ser Ile Arg Gly Phe Glu Asn Ser 435 440 445 Val Gly Leu Ser Gly Asn Asp Gly Phe Tyr Ile Lys Asn Thr Leu Ala 450 455 460 Phe Pro Leu Pro Gly Met Lys Ala Asn Tyr Tyr Ala Gly Leu Asp Phe 465 470 475 480 Gly Gln Val Tyr Gln Asp Ala Ser Tyr Gly Asp Glu Ser Leu Val Gly 485 490 495 Ser Ala Val Gly Ile Asp Gly Asn Ile Lys Ser Leu Glu Tyr Asn Phe 500 505 510 Ser Val Ser Thr Pro Leu Lys Tyr Pro Ala Thr Leu Asp Ile Asp Arg 515 520 525 Val Asn Val Asn Phe Asn Phe Ser Tyr Gln Met * 530 535 <210> 1042 <211> 123 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18274..18642) <400> 1042 Met Arg Ile Gly Thr Asp Ile Val Glu Ile Ala Arg Ile Thr Lys Ala 1 5 10 15 Ile Ile Asn Gly Glu Met Ala Phe Tyr Glu Arg Val Tyr Thr Ser His 20 25 30 Glu Arg Leu Leu Ile Asn Pro Ala Glu Pro Asp Tyr Glu Arg Ala Ser 35 40 45 Gly Phe Trp Ala Ala Lys Glu Ala Leu Val Lys Ala Ile Gly Cys Gly 50 55 60 Phe Arg Asp Gly Val Arg Phe Gln Asp Ile Glu Ile Lys His Asp Ala 65 70 75 80 Ala Lys Ala Pro Tyr Phe Val Ile Ser Gly Arg Leu Gln Glu Ile Phe 85 90 95 Ile Gly Gln Gly Leu Gln Asn Asn Ser Leu Ser Ile Ser His Cys Arg 100 105 110 Thr His Ala Ile Ala Thr Val Ile Val Tyr * 115 120 <210> 1043 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18848..19417) <400> 1043 Val Gln Cys Asp Leu Ala Cys Pro Gln Ser Val Ser Ala Leu Cys Glu 1 5 10 15 Gln Ile Glu Arg Gln Ala Gly Lys Ile Asp Val Leu Val Asn Asn Ala 20 25 30 Gly Ile Val Lys Asp Ser Leu Phe Ala Ser Met Ser Tyr Glu Asp Phe 35 40 45 Thr Gln Val Ile Glu Thr Asn Met Phe Ser Ile Phe Arg Leu Thr Lys 50 55 60 Asp Ala Leu Met Leu Leu Arg Ala Ala Glu Asn Pro Ala Ile Ile Asn 65 70 75 80 Val Ala Ser Ile Ala Ala Leu Ile Pro Ser Val Gly Gln Ala Asn Tyr 85 90 95 Ser Ala Ser Lys Gly Ala Ile Leu Gly Phe Thr Arg Thr Leu Ala Ala 100 105 110 Glu Met Ala Pro Trp Gly Val Arg Val Asn Ala Val Ala Pro Gly Met 115 120 125 Ile Glu Ser Lys Met Val Lys Lys Val Ser Arg Ala Val Val Arg Ala 130 135 140 Val Thr Ser Thr Ile Pro Leu Arg Arg Leu Gly Lys Cys Glu Glu Val 145 150 155 160 Ala Asn Thr Ile Val Phe Leu Ser Ser Ser Ala Ser Ser Tyr Ile Val 165 170 175 Gly Gln Thr Ile Val Ile Asp Gly Gly Leu Val Met Arg * 180 185 <210> 1044 <211> 183 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19421..19969) <400> 1044 Met Ser Lys Tyr Thr Ile Pro Ser Lys Ile Phe Leu Glu Met Gly Gly 1 5 10 15 Trp Arg Gln Pro Leu Leu Met Val Asp Lys Ile Ala Asp Tyr Lys Tyr 20 25 30 Gly Glu Asn Gly Phe Val Ser Val Val Lys His Val Thr Tyr Asn Glu 35 40 45 Pro Tyr Leu Leu Gly His Phe Pro Glu Asp Pro Ile Met Pro Gly Val 50 55 60 Ile Ile Ser Glu Ile Phe Gly Gln Ala Ser Glu Tyr Leu Ser Phe Leu 65 70 75 80 Thr Asp Ile Cys Asp Ile Trp Arg Glu Arg Phe Glu Glu Glu Leu Lys 85 90 95 Ser Leu Arg Asp Ile His Ala Arg Ile His Arg Pro Glu Met Leu Glu 100 105 110 Ile Ile Arg Thr Trp Arg Ser Gln Val Arg Gly Val Leu Ala Ala Gln 115 120 125 Asn Leu Lys Phe Lys Asp Ile Ala Tyr Pro Gly Asp Ser Ile Asp Val 130 135 140 Val Ser Lys Leu Ala Phe Ser Asp Ala Ser Gly Phe Lys His Tyr Ser 145 150 155 160 Val Thr Ala Tyr Val Gly Lys Lys Leu Ile Ser Gln Gly Thr Ile Ile 165 170 175 Asn Phe Arg Glu Thr Lys * 180 <210> 1045 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19991..20272) <400> 1045 Met Ser Thr Met Asn Asp Ala Ile Glu Gln Arg Lys Glu Val Leu Met 1 5 10 15 Thr Ile Lys Thr Glu Ile Ile Gln Arg Leu Asn Ile Gln Arg Asp Glu 20 25 30 Ala Gln Ile Asp Asp Asp Thr Ala Leu Phe Gly Asn Gly Phe Lys Leu 35 40 45 Asp Ser Val Asp Ala Thr Glu Ile Val Val Leu Leu Asp Lys Val Phe 50 55 60 Asp Ile Lys Ile Ser Glu Ser Asp Asp Pro Ser Tyr Met Arg Ser Ile 65 70 75 80 Asn Ser Leu Ala Thr Phe Val Ile Gln Lys Lys Asn Asp * 85 90 <210> 1046 <211> 387 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20308..21468) <400> 1046 Met Lys Ser Leu Ala Glu Phe His Leu Lys Asn Asn Ala Val Met Gly 1 5 10 15 Val Tyr Asn Asn Arg Thr Leu Pro Ser Ser Tyr His Asp Ala Met Thr 20 25 30 Glu Tyr Lys Ala Val Arg Glu Asn Ala Leu Leu Val Asp Tyr Ser His 35 40 45 Leu Ser Ile Val Ser Val Met Gly Asp Asp Ala Trp Ala Leu Ile Asn 50 55 60 Gln Leu Val Ser Ala Asp Val Ser Ile Ile Arg Asp Glu Gln Ala Ile 65 70 75 80 Tyr Ser Leu Val Leu Asn Glu Glu Gly Thr Ile Arg Gly Asp Val Tyr 85 90 95 Val Leu Cys Ser Ile Asp Gly Tyr Tyr Leu Leu Ser Glu Asp Ile Ser 100 105 110 Ala Ala Glu Leu Ile Ala Ser Met Asn Thr Ile Leu Glu Lys Ala Glu 115 120 125 Glu Leu Asp Ile Gln Ser Met Pro Glu Ile Gln Asp Met Arg Glu Asn 130 135 140 Asn Trp Gly Ala Ile Leu Leu Glu Gly Pro Tyr Ser Trp Glu Ile Met 145 150 155 160 Ser Glu Ile His Gly Phe Asp Val Ile Gly Leu Pro Tyr Tyr Glu Tyr 165 170 175 Met Asn Thr Glu Glu Asp Leu Leu Leu Phe Arg Cys Gly Lys His Gly 180 185 190 Glu Tyr Ala Tyr Met Thr Ile Gly Glu Gln Ala Lys Leu Ala Glu Gln 195 200 205 Trp Glu Lys Leu Leu Thr Val Gly Glu Lys Tyr Leu Met Gln Thr Gly 210 215 220 Gly Leu Asp Tyr Gln Lys Ile Val Arg Leu Glu Asn Pro Cys Trp Asp 225 230 235 240 Ala Ser Leu Trp Glu Gly Gln Ala Val Asn Pro Val Gln Leu Gln Met 245 250 255 Gln Trp Ala Val Gln Tyr Asp Lys Asp Asp Phe Ile Gly Lys Asp Ala 260 265 270 Val Thr Glu Leu Ser Gln Glu Tyr Thr Gly Asn Lys Leu Ile Gly Met 275 280 285 Ile Ala Gln Glu Glu Cys Glu Gly Ile Glu Ala Gly Asp Arg Val Leu 290 295 300 Val Glu Gly Gln Asp Val Gly Tyr Val Val Lys Ala Leu Phe Ser Pro 305 310 315 320 Ala Leu Gln Arg Phe Ile Ala Leu Thr Leu Leu Glu Lys Asp Tyr Ala 325 330 335 Trp Ser Asp Ile Ser Gly Tyr Glu Ile Gln Thr Ala His Gly Ile Ile 340 345 350 Pro Ala Gln Ser Lys Cys Met Pro Phe Ile Tyr Asn Leu Ser Met Leu 355 360 365 Val Ser Pro Thr Glu His Ser Tyr Ile Asp Ala Ser Lys Asn Lys Ser 370 375 380 Ala Ala * 385 <210> 1047 <211> 853 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21542..24100) <400> 1047 Met Lys Thr Asn Arg Lys Arg Val Val Ile Thr Gly Leu Gly Ile Leu 1 5 10 15 Ser Ser Leu Ala Glu Asn Ile Gln Asp Phe Arg Glu Ala Leu Leu Asn 20 25 30 Lys Lys Asn Gly Val Lys Asp Ser Glu Arg Phe Ala Lys Trp Phe Glu 35 40 45 Asn Ala Arg Ala Ala Glu Val Leu His Asp Ile Glu Tyr Ser Asp Leu 50 55 60 Asn Glu Asp Val Ile Asp Ser Leu Asp Asn Ala Ala Leu Trp Ala Tyr 65 70 75 80 Lys Val Gly Lys Asp Ala Leu Ser Gln Ala Gly Leu Met Asp Ser Arg 85 90 95 Asp Thr Leu Lys Glu Thr Gly Met Ile Val Gly Val Ser Ser Ala Gly 100 105 110 Thr Glu Ala Phe Leu Pro Leu Phe Glu Gln Arg Met Glu Asp Phe Ser 115 120 125 Leu Arg Lys Ala Leu Phe Ser Gly Ala Phe Ser Ser Cys Cys Ser Ser 130 135 140 Val Ser Thr Leu Leu Gly Leu Gln Gly Gly Val Glu Leu Val Ala Thr 145 150 155 160 Ala Cys Thr Ala Ser Pro Asn Ala Val Gly Met Ala Phe Asp Tyr Ile 165 170 175 Gln Asn Gly Lys Ser Lys Thr Met Leu Ala Val Gly Thr Glu Pro Ile 180 185 190 Tyr Leu Pro Thr Phe Ala Gly Phe Tyr Ala Leu Asn Val Met His Pro 195 200 205 Asp Thr Cys Thr Pro Phe Ser Gly Gln Ser Gly Met Ser Ile Gly Glu 210 215 220 Gly Ala Gly Ala Ile Val Leu Glu Glu Tyr Glu His Ala Val Ala Arg 225 230 235 240 Gly Ala Thr Ile Tyr Gly Glu Ile Leu Ser Tyr Ala Thr Ser Cys Asp 245 250 255 Ala Phe His Glu Thr Gly Pro Asp Pro Arg Ala Ser Gly Ala Val Gln 260 265 270 Val Met Asn Lys Ala Met Ala Asn Ala Gly Val Thr Pro Glu Gln Ile 275 280 285 Asp Tyr Val Asn Ala His Gly Thr Gly Thr Glu Ala Asn Asp Arg Ile 290 295 300 Glu Thr Leu Ala Met Lys Lys Val Phe Ala Asn His Asp Lys Leu Leu 305 310 315 320 Val Ser Ser Thr Lys Ser Tyr Phe Gly His Asn Ile Gly Ala Ala Gly 325 330 335 Ile Val Glu Leu Ile Ala Cys Leu Ala Thr Leu Pro Asp Asn Arg Val 340 345 350 Leu Pro Thr Leu Asn Phe Ser His Ala Arg Pro Asn Cys Asp Leu Asp 355 360 365 Tyr Val Pro Asn Glu Phe Arg Asp Arg Lys Val Asn Ile Phe Met Lys 370 375 380 Asn Asn Tyr Ala Phe Gly Gly Asn Asn Cys Cys Met Ile Leu Ser Met 385 390 395 400 Glu Pro Ala Ser Ile Pro Val Ser Thr Tyr Asp Ser Lys Arg Val Ala 405 410 415 Ile Ser Gly Val Gly Ala Val Ser Ala Ile Gly His Thr Leu Asn Gln 420 425 430 Val Leu Glu Asn Ile Trp Ala Gln Asp His His Val Glu Leu Gly Ser 435 440 445 Val Thr Phe Pro Asp Asp Thr Leu Glu Glu Ala Lys Glu Leu Leu Ala 450 455 460 Val Leu Asp Glu Ser Asn Gln Phe Ala Glu Leu Phe Asp Glu Glu Tyr 465 470 475 480 Ser Phe Ser Glu Ala Thr Leu Pro Glu Thr Glu Ser Asn Phe Lys Thr 485 490 495 Phe Gln Val Ser Gly Leu Glu Pro Arg Lys His Leu Arg Arg Phe Asp 500 505 510 Gln Arg Lys Ala Thr Arg Gly Gly Thr Phe Ala Leu Ile Ala Leu Thr 515 520 525 Glu Ala Leu Glu Gln Ala Lys Arg Lys Ile Lys Arg Asp Gly Asp Glu 530 535 540 Leu Gly Met Ile Met Gly Met Ser Arg Gly Pro Gln Glu Thr Thr Tyr 545 550 555 560 Lys Tyr Leu Gln Ser Leu Lys Pro Asp Pro Arg Lys Val Arg Thr Ser 565 570 575 Glu Phe Pro Gly Ser Leu Met Asn Ala Ile Pro Thr Phe Cys Gly Ile 580 585 590 Ser Glu Gly Ile Lys Gly Tyr Thr Thr Thr Leu Ala Thr Gly Glu Asn 595 600 605 Ser Ala Leu Gly Ala Leu Thr Tyr Gly Tyr Glu Ile Val Arg Gln Asn 610 615 620 Leu Gln Pro Gln Val Leu Val Gly Gly Ala Asp Glu Tyr Phe Pro Ser 625 630 635 640 Met Ser Leu Tyr Met Asp Ala Val Thr Gln Lys Ile His Met Thr Ala 645 650 655 Glu Ala Ser Asp Tyr Gln Ile Tyr Gly Lys Asp Pro Gln Gly Tyr Val 660 665 670 Pro Gly Glu Gly Ala Cys Met Leu Leu Leu Glu Asp Pro Gln Leu Ala 675 680 685 Val Ala Arg Gly Ala Glu Val Leu Ala Glu Val Val Gly Tyr Gly Lys 690 695 700 Ser Cys Ser Asn Thr Tyr Phe Asp Ala Ser Leu Leu Glu Glu Lys Ser 705 710 715 720 Ala Ser Met Ala Leu Ala Ile Glu Arg Ala Leu Thr His Ala Gly Ile 725 730 735 Ser Ala Gly Asp Ile Asp Leu Val Cys Gly Thr Ser Asn Gly Ser Asp 740 745 750 Asp His Ser Arg Ile Glu Ile Asp Ala Ile Tyr Asn Thr Phe Ala Ala 755 760 765 Gln Asn Pro Ala Val Pro Val Val Asn Tyr Asn Ala Cys Phe Gly Phe 770 775 780 Val Ala Ser Ala Ala Gly Leu Leu Asn Leu Ala Val Ile Thr Asp Cys 785 790 795 800 Ile Lys Lys Gln Ala Val Pro Ala Ile Pro Asn Thr Val Glu Phe Phe 805 810 815 Asp Glu Arg Val Asn Phe Val Arg Gln Ser Met Lys Leu Ala Leu Asn 820 825 830 His Val Leu Leu Val Gly Ala Thr Glu Gly Gly Asn Tyr Tyr Ala Phe 835 840 845 Val Ile Lys Gly * 850 <210> 1048 <211> 327 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(24348..25328) <400> 1048 Met Leu Asp Lys His Cys Leu Ala Gly Arg Asn Val Arg Val Tyr Leu 1 5 10 15 Thr Gly Ile Gly Pro Arg Ile Asp Gly Leu Asp Tyr Lys Ser Phe Tyr 20 25 30 Asn Tyr Asn Asp Val Glu Asp Ile Asn Leu Thr Gln Ser Ile Thr Asn 35 40 45 Leu His Ala Ser Lys Met Ser Gln Asp Thr Ile Ser Ser His Leu Ala 50 55 60 Arg Lys Tyr Arg Leu Gln Tyr Leu Pro Pro Asn Met Asn Cys Thr Ser 65 70 75 80 Asn Ser Ser Leu Thr Ala Val His Leu Ala Thr Gln Gly Ile Glu Gln 85 90 95 Gly Gly Ile Asp Leu Ala Ile Val Leu Asn Cys Ser Lys Ile Lys Thr 100 105 110 Gln Asp Ile Trp Phe Leu Glu Thr Gln Ser Met Leu Asp Ser Glu Gln 115 120 125 Val Gln Pro Phe Gly Glu Asn Ser Lys Gly Val Ala Phe Ala Glu Gly 130 135 140 Phe Ser Ala Leu Leu Leu Glu Ser Ala His His Arg Arg Ala Arg Gln 145 150 155 160 Gln Ser Glu Gly Val Arg Val Gln Thr Thr Tyr Thr Gln Ile Ser Ala 165 170 175 Gly Arg Ser Asn Asp Ala Ser Trp Leu Ser Thr Asn Val His Lys Val 180 185 190 Met Gln Ala Ala Met Lys Gln Ala Glu Ile Ala Leu Asp Asp Leu Ala 195 200 205 Ala Ile Leu Pro His Gly Asn Gly Ser Ala Val Ser Asp Asn Ala Glu 210 215 220 Ala Lys Ala Ile Ala Met Phe Ala Gly Glu Arg Gln Ile Pro Val Leu 225 230 235 240 Ala Tyr Lys Gly Gln Ile Gly Tyr Thr Ala Thr Gly Ser Gly Val Val 245 250 255 Asp Leu Ile Ile Gly His His Ser Leu Thr His His Gln Leu Ile Ala 260 265 270 Pro Val Gly Asn Asp Val Ile Ile Asp Ser Met Ala Ser Leu Val Leu 275 280 285 Thr Asp Gly Ser Val Thr Asn His Ser Lys Arg His Leu Leu Lys Val 290 295 300 Gly Val Gly Val Asp Gly Ser Val Ile Gly Val Val Met Thr Asn Met 305 310 315 320 Gln Ala Gly Arg Ala Lys * 325 <210> 1049 <211> 284 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(25427..26278) <400> 1049 Met Tyr Glu Arg Gly Leu Tyr Gly Thr Arg Ala Asn Gly Trp Gly Leu 1 5 10 15 Lys Arg Phe Gly Val Glu Asn Asp Ile Tyr Ala Pro Glu Arg Ile Arg 20 25 30 Asn Pro Gln Tyr Met Pro Tyr Leu Glu Ala Met Glu Gln Val Thr Asp 35 40 45 Ser Ala Leu Gln Gln Met Pro Thr Lys Glu Arg Met Lys Leu Met Lys 50 55 60 Ser Arg Thr Ala Phe Ile Tyr Ala Asp Ser Trp Gly Glu Ser Gly Ser 65 70 75 80 Phe Glu Lys Ile Ser Ser Ala Leu His Ile Ala Thr Ile Asp Thr Leu 85 90 95 Pro Lys Asn Leu Leu Lys Lys Phe Ser Ile Thr Glu Pro Thr Cys Lys 100 105 110 Ile Arg Gly Glu Lys Gln Ala Phe Val Gln Ala Leu Arg Met Ala Gln 115 120 125 Asp Tyr Leu Ala Trp Asp Val Phe Asp Asn Val Val Ile Cys Ala Ala 130 135 140 Tyr Arg Ala Ile Pro Val Leu Val Phe Ser Glu Glu Asp Val Gly Lys 145 150 155 160 Pro Pro Lys Arg Leu Phe Pro Arg Arg Ala Asp Glu Val Asn Leu Ser 165 170 175 Val Glu Arg Val Gly Cys Phe Ile Leu Ser Gln Arg Glu Ser Ala Ile 180 185 190 Arg Leu Gln Cys Gly Glu Tyr His Ser Gly Thr Ala Pro Gln His Ala 195 200 205 Thr Asp Ile Asp Val Met Ala Phe Ser Glu Arg Gln Gln Met Pro Ser 210 215 220 Arg Pro Ala Ala Gly Val Ile Asp Leu Val Ala His Tyr Gly Glu Ser 225 230 235 240 Gly Cys Leu Thr Pro Ala Leu Ser Met Asp Tyr Leu Thr Arg His Ile 245 250 255 Gln Pro Gly Gly Lys Met Arg Thr Val Ile Ala Asp Lys Gln Phe Gly 260 265 270 Tyr His Tyr Phe Asp Leu Glu Tyr Leu Glu Gly * 275 280 <210> 1050 <211> 236 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26289..26996) <400> 1050 Met Gln Ser Thr Ile Lys Ser Leu Pro Ala Ile Ser Leu Ser Asn Ile 1 5 10 15 Tyr Lys Cys Tyr Gly Ala Gly Ala Gly Lys Val Asp Ala Leu Lys Ser 20 25 30 Ile Asn Leu Asp Ile Asn Lys Gly Glu Phe Leu Ala Leu Cys Gly Pro 35 40 45 Ser Gly Ser Gly Lys Ser Thr Leu Leu Asn Ile Leu Ser Gly Ile Asp 50 55 60 Lys Pro Thr Ser Gly Thr Val Ile Phe Leu Asn Lys Leu Leu Asn Gln 65 70 75 80 Leu Pro Glu Glu Gln Leu Ala Val Ile Arg Gly Lys His Leu Gly Phe 85 90 95 Ile Phe Gln Phe Phe Asn Leu Met Pro Val Leu Asn Val Phe Asp Asn 100 105 110 Val Tyr Phe Pro Leu Val Leu Asn Gly Gln Phe Ser Lys Lys Glu Ala 115 120 125 Thr Glu Arg Thr Leu His Tyr Leu Asp Ser Val Gly Leu Ser Gly Phe 130 135 140 Gly Asp Arg Lys Pro Gly Gln Leu Ser Gly Gly Gln Gln Gln Arg Val 145 150 155 160 Ala Ile Ala Arg Ala Leu Ala His Glu Pro Met Val Val Ile Ala Asp 165 170 175 Glu Pro Thr Gly Asn Leu Asp Leu Ala Thr Gly Glu Ala Ile Leu Asp 180 185 190 Leu Leu Leu Thr Ile Asn Gln Gln Thr Gly Thr Thr Phe Val Ile Ser 195 200 205 Thr His Ser Ser Glu Leu Lys Ala Arg Ala Arg Arg Val Val Glu Ile 210 215 220 Gln Asp Gly Val Leu Ile His Asp Ser Asp Ala * 225 230 235 <210> 1051 <211> 219 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(26980..27636) <400> 1051 Met Thr Gln Met His Lys Gly Phe Leu Leu Ile Gly Val Phe Leu Tyr 1 5 10 15 Ala Ala Phe Val Ala Pro Lys Ile Tyr Ala Ala Thr Pro Asp Ala Val 20 25 30 Asn Gln Val Leu Gln Gln Gly Leu Pro Ala Gln Pro Ala Ala Leu Ala 35 40 45 Thr Leu Thr Glu Ala Leu Lys Lys Glu Tyr Glu Ala Arg His Asn Val 50 55 60 Val Ala Leu Val Phe Tyr Ala Tyr Gly Leu Leu Arg Gln Ala Asp Gly 65 70 75 80 Tyr Ala Ala Thr Asn Asp Phe Ile His Ala Ser Glu Tyr Ala Lys Ser 85 90 95 Gly Phe Phe Trp Leu Asp Glu Ala Val Asp Leu Gln Glu Lys Asn Gln 100 105 110 Arg Val Arg Tyr Leu Arg Ala Arg Val Asp Ala Tyr Leu Pro Ala Asp 115 120 125 Ser Gly Arg Cys Val Val Thr Val Lys Asp Thr Glu His Met Leu Ala 130 135 140 Asp Pro Ala Ile Trp Thr Thr Thr Ile Arg Asp His Ile Leu Ala Met 145 150 155 160 Arg Tyr Arg Ala Leu Arg His Cys Lys Asp Thr Thr Arg Ala Asn Ala 165 170 175 Leu Leu Ala Gln Ile Lys Gly Gln Asn Ala Ala Leu Ala Gln Ser Leu 180 185 190 Thr Gln Asp Phe Asn Val Val Pro Glu Trp Asp Ser Glu Glu Leu Thr 195 200 205 Gln Val Leu Leu Pro Leu Met Lys Gly Glu * 210 215 <210> 1052 <211> 437 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27637..28947) <400> 1052 Met Ser Gly Glu Ile Leu Ala Val Asn Cys Val Leu Leu Leu Ile Leu 1 5 10 15 Phe Phe Val Phe Tyr Gln Leu Leu Phe Tyr Ser Arg Asp Val Lys Phe 20 25 30 Ala Phe Leu Asn Leu Phe Arg His Lys Arg Arg Ser Phe Ser Thr Ile 35 40 45 Thr Ala Ile Val Leu Gly Gly Val Ala Ile Phe Leu Tyr Gly Gly Phe 50 55 60 Ile Asp Tyr Ser Phe Trp Ile Leu Lys Glu Gln Thr Ile Arg Thr Asn 65 70 75 80 Ile Gly His Val Gln Ile Tyr Asn Gln His Tyr Phe Glu Thr Ser Asn 85 90 95 Lys Asn Lys Ser Leu Ile Ala Asp Tyr Ala Ala Leu Lys Lys Ala Ile 100 105 110 Leu Ser Asp Pro Thr Leu Ala Ala Asp Ile Ser Thr Leu Ser Gly Gln 115 120 125 Leu Glu Phe Thr Gly Val Ile Ser His Tyr Glu Ser Glu Thr Ser Ser 130 135 140 Tyr Phe Ser Ala Leu Gly Val Glu Pro Leu Pro Ala Leu Lys Leu Gly 145 150 155 160 Ser Phe Asp Lys Ile Ile Ala Gly Ser Asp Leu Ser Arg Val Lys Gly 165 170 175 Asp Glu Ile Thr Leu Gly Ser Gly Leu Ala Lys Thr Leu Asn Ala Lys 180 185 190 Tyr Asp Asp Trp Leu Asp Val Met Val Val Asn Thr Ala Gly Gly Gln 195 200 205 Gly Ala Leu Ser Leu Lys Met Arg Gly Ile Phe Glu Ser Gly Ile Lys 210 215 220 Asp Tyr Asp Asp Val Ala Met Lys Ile Pro Leu Asp Thr Ala Gln Arg 225 230 235 240 Met Met Gly Thr Asp Gly Val Ser Lys Val Leu Ile Leu Leu Lys Glu 245 250 255 Asp Asp Thr Ala Ala Phe Ser Ala Lys Leu Arg Gln Phe Ile Glu Arg 260 265 270 Asn His Leu Pro Leu Val Val Lys Asp Trp Arg Asp Val Ser Leu Phe 275 280 285 Tyr Gln Gln Val Glu Gly Leu Leu Ser Gly Ile Tyr Phe Phe Ile Lys 290 295 300 Leu Ile Val Ala Leu Ile Val Ile Phe Met Ile Gly Asn Ser Met Ala 305 310 315 320 Met Asn Ile Val Glu Arg Thr Arg Glu Ile Thr Thr Leu Arg Ala Ile 325 330 335 Gly Leu Lys Pro Leu His Val Thr Arg Leu Phe Leu Thr Glu Gly Ile 340 345 350 Phe Ile Gly Val Ile Gly Ala Val Gly Ser Leu Leu Val Gly Gly Val 355 360 365 Leu Ala Trp Ile Ile Asn Leu Tyr Gly Ile Ala Met Pro Pro Ser Pro 370 375 380 Gly Gln Thr Ile Gly Tyr Thr Ala Phe Ile Lys Thr Ser Asn Pro Glu 385 390 395 400 Leu Ile Trp Val Thr Val Val Leu Pro Ile Leu Thr Ala Thr Gly Ala 405 410 415 Ser Val Leu Pro Ala Leu Arg Ala Ser Arg Leu Asn Ile Ser Asp Ala 420 425 430 Phe Lys Phe Ser * 435 <210> 1053 <211> 263 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(28956..29744) <400> 1053 Met Asn Met Ala Phe Tyr Gly Lys Trp Phe Ala Cys Leu Trp Leu Ala 1 5 10 15 Thr Ser Cys Val Gln Ala Ala Ser Thr Asp Asn Lys Ala Leu Glu Ile 20 25 30 Ile Arg Arg Ala Asp Glu Ile Arg Ser Pro Asn Lys Pro Phe Arg Tyr 35 40 45 Thr Leu Thr Val Thr Glu Tyr Lys Ala Gly Ala Thr Gln Pro Glu Asn 50 55 60 Lys Gln Val Leu Asp Ile Ser Met Arg Phe Met Lys Pro Gln Gly Asn 65 70 75 80 Glu Lys Ala Asp Ala Arg Ser Leu Val Arg Phe Ile Tyr Pro Pro Arg 85 90 95 Asp Lys Gly Lys Ile Met Leu Ser Asp Trp Tyr Asp Leu Trp Phe Tyr 100 105 110 Thr Pro Glu Leu Arg Arg Pro Met Pro Ile Ser Arg Gln Gln Arg Leu 115 120 125 Ile Gly Gln Ile Ser Asn Gly Asp Val Ile Val Thr Asn Phe Glu Tyr 130 135 140 Ala Tyr Asp Ser Thr Leu Met Gly Glu Val Thr Cys Ala Glu Lys Gln 145 150 155 160 Cys Tyr Lys Leu Ala Leu Val Arg Lys Ser Ala Asp Ile Thr Trp Pro 165 170 175 Lys Val Ile Tyr Tyr Val Glu Lys Asp Gly Asp Asn Arg Pro Trp Lys 180 185 190 Ala Ala Tyr Tyr Ser Gln Asp Asp Gln Leu Ile Lys Glu Val Leu Tyr 195 200 205 Gln Asp Phe Gln Pro Val Leu Gly Lys Thr Arg Pro Met Lys Ile Thr 210 215 220 Val Thr Asp Val Arg His Gly Asn Asn Tyr Ser Val Met Glu Tyr Ser 225 230 235 240 Asp Val Arg Leu Glu Ser Leu Pro Glu Phe His Phe Thr Lys Glu Tyr 245 250 255 Ile Gln Arg Gly Ala Lys * 260 <210> 1054 <211> 463 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(29741..31129) <400> 1054 Met Lys Arg Thr Leu Lys Ile Ser Ser Leu Leu Cys Val Ala Leu Pro 1 5 10 15 Leu Thr Val Gln Ala Asp Cys Leu Ser Gly Asp Glu Val Ala Gln Asn 20 25 30 Ser Asp Val Thr Leu Tyr Glu Gln Val Ser Tyr Val Asn Lys Gln Ala 35 40 45 Ser Ala Trp Gln Ile Ala Gly Lys Asn Pro Tyr Thr Arg His Asn Gly 50 55 60 Tyr Gln Glu Ala Gly Ile Gly Ile Asn Ser Gly Cys Ser Ile Ile Asp 65 70 75 80 Asn Thr Leu Asp Leu Lys Leu Asn Leu Tyr Gly Ile Asn Glu Tyr Ala 85 90 95 Leu Lys Pro Ala Gly Lys Phe Glu Thr Asp Asp Ser Arg Thr Arg Ala 100 105 110 Leu Ile Asn Arg Leu Ser Leu Val Tyr Ser Ala Ser Asp Ser Val Gln 115 120 125 Phe Glu Ala Gly Lys Phe Ala Ala Pro Ser Gly Met Phe Phe Leu Arg 130 135 140 Ser Pro Ser Asp Leu Gln Thr His Tyr Tyr Thr Gly Phe Gln Ser Thr 145 150 155 160 Arg Leu His Asp Pro Lys Met Thr Ser Ala Tyr Gln Ala Ser Ser Trp 165 170 175 Gly Ala Lys Met Ser Val Asp Thr Arg Asp Tyr Ala Phe Ser Ala Ser 180 185 190 Val Ile Pro Lys Leu Ala Thr Ile Asp Lys Arg Tyr Val Thr Ser Gly 195 200 205 Asn Trp Ser Ala Asn Gln Gln Gly Asn Ser Asp Glu Ala Tyr Leu Leu 210 215 220 Ser Phe Ser Asp His Arg Phe Gly Glu His Thr Pro Thr Val Asn Val 225 230 235 240 Arg Leu Gly Pro Ser Pro Ser Leu Ala Leu Ser Asp Ser Tyr His Tyr 245 250 255 Thr Pro Gln Leu Thr Leu Asn Val Asp Ala Ala Tyr His Arg Ser Gln 260 265 270 Gln Trp Arg His Leu Ser His Arg Glu Thr Ala Gln Val Glu Glu Tyr 275 280 285 Gln Phe Pro Asp Ser Leu Tyr Glu Thr Lys Asp Glu Ser Gly Val Glu 290 295 300 Leu Ala Leu Gly Gly Gln Tyr Thr Ser Asp Asn Phe Ser Val Phe Gly 305 310 315 320 Val Glu Tyr Tyr Phe Gln Ser Glu Gly Tyr Ser Arg Ala Glu Gln Arg 325 330 335 Gln Gln Arg Glu Leu Ile Asp Phe Leu Asn Thr Thr Thr Gly Tyr Ala 340 345 350 Pro Leu Asp Gln Ala Phe Asp Ser Tyr Lys Tyr Leu Met Ala Ser Glu 355 360 365 Ile Ser Asn Thr Ala Asn Gln Gly Met Leu Gln Gly Lys His Tyr Leu 370 375 380 Asn Ala Trp Ala Ser Leu Pro Leu Ala Gly Glu Ser Thr Leu Gln Pro 385 390 395 400 Ser Leu Val Val Asn Leu Val Asp Gly Ser Thr Leu Leu Gly Leu His 405 410 415 Tyr Ser Thr Pro Leu Ser Ala Ile Ser Asn Gln Leu Glu Ala Tyr Ala 420 425 430 Gly Gly Tyr Ser Ala Leu Gly Ser Arg Tyr Ser Glu Phe Ala Leu Phe 435 440 445 Gly Asp Thr Leu Gly Leu Tyr Leu Gly Phe Lys Tyr Tyr Leu * 450 455 460 <210> 1055 <211> 25473 <212> DNA <213> Escherichia coli O157:H7 <400> 1055 gcgcctttgt ctttaattca aattaccttt cttattcctt taataaataa gtcacaaaaa 60 aatgatatat acgcgataaa tctgtgatgc taatcactta ttaccgtgga ttatttttaa 120 tgtgtatgat ggtaatctaa aagtcgtagt gtattctaaa taaataacgt ataagctttt 180 tagctgcatt tctttgccca tatcaatgat cgacaaaaga gatgcacaag ttattaccct 240 tcttaataaa acgagactgg ttataaaaac cagttaaaat aatgacctgg aaggaagtga 300 cttatctatg gcgcgattcc agtttaaaaa ccgtaaaaat aatggactta ttttttttat 360 aagttttatg gtgatgggag aagctgcaat tgctgcaccg ctgccacaat gggcgaatgc 420 cccagcggta acgccagttg cccaattatc tttacaggaa agtatattac gcgcctttgc 480 gcgaaatccc ggtgtcactc aacaggcggc gcagataggt attggcgaag cgcaaattga 540 tgaagccaaa agtgcctggt atccgcacgt tggattaacc ggcaacgcgg ggccgtcccg 600 acaaacggac tccagcggca ggcttgataa caacgtttcg tatggcataa ccctgacaca 660 actggtgtat gactttggta aaactaacaa cgatatcaat ctgcaaactg ccgcccgtga 720 cagctaccgc tttaaattga tggcaacctt aaccgatgtt gcagagaaaa cggcgactgc 780 ctacatggaa gtcagtcgtt atcaggcttt gtgcgatgcg gctcaacgca atattcactc 840 gctggaaaac gtctacaaca tggcggcatt gcgcgctaac gcaggcctga actcatcgtc 900 ggatgaatta caggcccaga cgcgtattgc cggaatgcgc tcaacgctgg agcaatatca 960 ggcgcagatg gcgagcgcca aagcgcaact ggcggtgctc actggcgtac agccggaggc 1020 gatagccgcg ccacctgctg aattagccga gcagccggta tcgctgaaga atattgatta 1080 ccagtccatc ccgctggtgc tggcggcaga aaacttacgc cagtcagcac agtacggcgt 1140 ggaaaaaacg aaagcgcaat actggccaac gctcagtatt caggggggta aaacgcgcta 1200 ccagaccagc gaccgctcgt attgggatga tcagctacaa ctgaacgtta acgcgccgct 1260 gtatcagggc ggcgcggttt ctgcccaggt gcaacaggcc gaagggcaac aaaaaatctc 1320 tgcctcgcag gtcgaacagg caaaactgga tgtgctgcaa cgagcgtctg tggcatatgc 1380 gaactggacc ggcgcacggg gtcgtgaaga agccggttta gcgcaatccg aaagtgcgca 1440 caaaacgcga gatgtgtacc aaaatgaata taaattgggt aaacgcagtc tgaatgatct 1500 attaaccgtc gaacaagatg tctttcaggc gcaatcggct gaaataaatg ccaattatga 1560 tggctgggtc gccgccgtaa attatgccgc tgcggtgaat aaccttattc cattagcggg 1620 aattaaacag ggcttataca acgacttacc cgacttgaaa taatcctgcc attattaata 1680 gtgggccgtt gttaagtgat tacctttgtc ttatttagat aaatggactc gctaaggatg 1740 tgcgccattt atcaggaatg ccattatgag cctgattatt gatgttattt cgcgtaaaac 1800 atccgtcaaa caaacgctga ttaatcctgg cgacgtcacg gttgttattt atgagccttc 1860 cgtggtgcag gttcatgctc aggcctctgc cgttgcgcgt tacgtccgtg aaggaaatga 1920 cctgctgatc tatatgcagg acggcacggt gatccgctgc aacggttatt tcctgcaagc 1980 ggcgaataca gctgaacaat cggaactggt gtttgccgat ggtcaacagc taacccatat 2040 cacctttgcc gatactgctg cgggtggatt agcccccgta gaactgactg cccagaccac 2100 tgcgattgaa agcattgcgc catttcttga taccgttgct cagaccagcg ccttcccgtg 2160 gggttggctg gcgggggcgg cggtaggtgg tggcgcgctt ggtgcactgc tggcaagcgg 2220 tggcgatggc gactcgaaaa cagaagtgat taataaccct acgccacctg ctgagcctgg 2280 caacgccaca ccatcatttt tagttaccga taatcagggc gatcagcgcg gcattctagc 2340 caccaatgac atcaccgatg acaccacgcc aacctttagc ggcagcgggc aggcgggggc 2400 gactattcag attaaagaca gtaacggcaa tactattgcc agtactcagg tagacaacaa 2460 cggtcactgg agtgtctcgt tacccacgca aagtgcaggt gaacatacct ggtcagtggt 2520 gcaaattgtc ggcagtacca tcactgacgc cggttcgata acgttaacca tcgacaatag 2580 tcaggccagc gtgcaggttg ccaccaccgc aggcgataac attattaacg ccagcgaaca 2640 ggccgccggg tttacgcttt ctggcaccag tagccatctg gcgcagggaa cagaactcac 2700 cgttacgcta aacggcaaaa cctacacgac cagcgtaggc gctaacggtg cctggagcgt 2760 gcaggtgccg accgccgatg cacaggcgtt aggcgaaggg aatcaggcgg tgctggtcag 2820 tgggaaagac gccacaggca atacggtcac cggcgcgcag ctactaacgg tcgataccca 2880 accgccaacg cttgccatca acaccatcgc tcaggacaac attatcagtg ctgcggaaca 2940 taacgtcgcg ctggtactga gcggcacgtc gaatgcagaa gcggggcaaa ccgtaacact 3000 gaccgtcaac gggaaaagcc atacagcaac cgtcggtagc gacggaacct ggcaagtgac 3060 gctgcctgcc acggaagtcc aggcactggc ggagggtaat tacgctgtca atgccagtgt 3120 cagcgatcgg gcagggaaca ccaccagcca cagcgcgaat ttcacggtag acacctcagc 3180 acccgtggtc agtgttaata ccgtggcggg cgacgatatt cttaataatg ccgagcaggc 3240 cgtcgcgcag atcatctccg gacaagtcag cggtgcttct ccaggcgata cggtaacggt 3300 gaaattgggc actcatgtcc tgacgggcat cgtgctggca gatggcagct ggaatgtggc 3360 gctggaccca gcggtaaccc gcacgctgga tcgcggagcc aatacgattt tcgtcaccgt 3420 gacagatgct gcaggaaata ctggcgcggc gtctcgagca atcacgctgg tcggtgtttc 3480 tccgttgatc accattaaca ccgtctccgg cgatgacatt atcagtggcg cagaaaaagg 3540 tgcgccactg acccttaccg gtagcactca acaggctgag acaggacaaa ccgtcacagt 3600 aaccctggct ggacagagtt ttaccactac cgtgcaggcc gatggctcct ggagtctgac 3660 ggtacctgcc gccgcgatgg gaaatctgcc tgacggcgcg gtggcgatta ccgcttctgt 3720 gacggatctc agcggcaata ccggcaacac ttcccgcacc attaccgtcg atagccaggc 3780 cccggcctta agcattgatc cactgaccgc tgataacatc attaacgccg ccgaaagcgg 3840 gcaggatctg cccatcaccg gcaccaccga cgctcagccg gggcagacgg tgaccgttac 3900 gttaaatggg cagacgtatc agggcgtcgt gcagccagac ggcacctgga gcgtgactgt 3960 gcccgccgcc aacgtgggcg cactggctga cggcaacgct acggtcaccg ccagcgtgaa 4020 cgatgtcgcc ggtaatccga gcagcgtttc acgcgtggcg ctggtggatg ccacgccgcc 4080 ggtggtaacc attaatccgg tggcgaccga taacgtcatc aacacgccgg aacatgctca 4140 ggcgcaaatc atcagcggca cggttactgg cgctcaggcg ggcgatatcg tcaccgtgac 4200 gctgaataat gtggattaca ccacggtggt ggatggttcc ggcaactgga gtctgggcgt 4260 tccggcctcg gtggtcagtg ggctggcgga cggcagttat cctgtcagcg tctcggtaac 4320 cgacaaagcc ggaaacacgg gcagccagtc attgaccgtc acggtcaata ccgccgcgcc 4380 ccttatcggc attaacagca ttgcgggcga tgatgtgatt aacgccagcg aaaaaggggc 4440 cgatctccag attaccggca ccagcgatca gcctgttaac accgccatca ccgtgacgct 4500 gaacgggcaa aattacacca ccacgaccga cgcctccggc aactggagcg tcaccgttcc 4560 ggcatcggcg gttacagcat taggccaggc caactatacg gtaacggcgg cggtgaccag 4620 cgatatcggc aacagcgcca ctgccagcca taacgtgctg gtcgacagcg cgctgcccgg 4680 tgtgaccatt aatccggtgg caaccgacga tattattaac gccgccgaag cgggcgtggc 4740 gcaaaccatc agcgggcagg tgactggcgc ggaagatggc gacacggtaa ctattacgtt 4800 gggtggtaat acttatacgg cgacggtggg cagcaatctc acctggagcg tggacgttcc 4860 agcggcagat attcaggcgc tgggaaatgg cgatttaacg gttaatgcct cagtcaccaa 4920 tcaaaacggc aacaccggca gcggcacgcg ggatatcacc atcgacgcca atctgcccgg 4980 cctgcgggtc gatacggtgg cgggcgatga tgtggtcaat atcatcgagc acgggcaggc 5040 gctggtggtc accggcagca gctcggggct ggctgaaagc acgccgctta ccgttacgat 5100 taataatgtg gaatacacca ctgcggtgca ggccgatggt agctggagcg tgggcgtcac 5160 ggcggcgcag gttagcgcct ggcctgcggg gacggttaat attgccgttt caggggaaag 5220 tagcgccgga aactcggtga gcattacgca tccggtgacg gtggatctca ctccggcagc 5280 gatcaccatc aacaccatcg ccacggacga tgtgattaac gccgcagaaa aaggcgctga 5340 tttaaccctt tccggcacca ccactaacgt agaacccggt caaaccgtca ccgtcacctt 5400 tggcgggaaa aattacactg ccagcgtagc gagcgatggt agctggactg ccaccgtacc 5460 cgccgccgat ctggcgtcat tacccgaggg cagcgcctcc gcactggcca gcgtcagcaa 5520 tatcaacggc aatagcgcct cggcggtgca caactacagc gtcgacagca gcgcgccaac 5580 catcattatc aataccgtcg ccagcgacaa tatcgtcaac gccagcgaag ccgatgcggg 5640 cgtgacggtg agcggcagta ccaccgccga agcggggcag attgttacga taacgcttaa 5700 cagcccgacc gtgcagacct atcaggcaac ggtgcaggcg gacggcagct ggagcatcaa 5760 tattccggcg gcagatcttg aggcattgac cgatggcagc cacaccctga ccgccacggt 5820 caatgacaaa gcgggcaatc cggcgagcac cacgcataat ctggcggtgg atctcaccgt 5880 tccggtgctg accatcaaca ccattgcggg cgatgacatt attaacgcca ccgaacacgg 5940 gcaggcgctg gtgatttccg gttccagcac cggcggagaa gcgggggatg tcgtcaccgt 6000 cacgctaaac agtaaaacct acaccaccac cctggacgcc tccggcaact ggagcgtcgg 6060 cgttccggcg gcggatgtca cggcgcttgg cagcggcccg caaactgtca ccgccacggt 6120 taccgatgcg gcaggcaaca gcgacaatta gacacacacg gtcaccgtta acctcaccgc 6180 accaaccatt gacatcaaca ccatcgccac cgatgacata attaacgcca gcgaaaaagg 6240 cgcggatctg caaatttccg gcaccagtaa tcagccagca ggcaccacga ttacgctggc 6300 gcttaacggg caaaattaca ccgcgacgac ggacgctgca ggcaactgga gcactacggt 6360 gccagcttcc gcagtaggtg cgctgggcga agccagctac acggtgacgg cgaacgtcac 6420 cgacagcgca ggcaacagca attccgccag ccataacgtg caggtcaata ccgcgctgcc 6480 tggcgtcacc attaacccag ttgcgaccga cgatattatt aacgccgccg aatcgggcaa 6540 tgcgcaaacc atcagcggcc aggtgacggg ggcggcggcg ggcgatacgg ttaccgtaac 6600 gcttggcggg aaaacttaca ccgctaccgt gcaggggaat ttaagctgga gcgtggacgt 6660 tccggcggcg gatattcagg ccatcggcaa tggcaatctg acggttaacg cttcggtgac 6720 caacggcgtt ggcaatactg gcagcggttc gcgagatatt actatcgacg ccaacctgcc 6780 aggtctgcgc gttgacaccg tggcgggcga tgatgtggtc aatagcatcg agcacgctca 6840 ggcgctggtg ataactggta gcagcagcgg gctggcggcg ggcgcggcgc tgacggtggt 6900 gattaacacg gtcacttacg ctgcaacagt attagccgat ggcacatgga gcgttggtgt 6960 tccggcggca gacgtgagta actggcctgc gggtacggtg aatatcacgg taagtggcac 7020 taacacagcc ggaacaacat ccaccatcac ccatccggtc accgtcgatc tggcggcggt 7080 ggcgatttcc attaacaccg tttccggcga cgatgtgatt aacgccgccg aaaaaggggc 7140 agatttaacc ctttccggca gcacctccgg cgtggaagtg gggcaaacgg tcaccgttac 7200 ctttggcggg aaaacctaca ccgctaccgt agcgggcgat ggtagctgga caaccaccgt 7260 acccgccgcc gatctcagcg tgttacgcga cggcgacgcc accgtgcagg ccagcgtcag 7320 cactattaac ggcaacacgg cttcggcaac ccacgcctac agcgtcgatg ccacggcccc 7380 gacgcttgcc attaacacca tcgccaccga cgatattctg aacgctgccg aggcgggcaa 7440 tccgttaacc atcagcggta gcagcaccgc cgaagcgggg cagacggtaa ccgtcacgct 7500 taatggtgtg acttacagcg gctccgtcca ggcggacggc agctggagcg tcagcttacc 7560 gacggcggat ctcagcaatc tgaccgccag ccagtacacc gttagtgcct cggtaagcga 7620 taaagcgggt aacccggcgt ccgctaacca cgggctggcg gtggatctca ccgtgccggt 7680 gctgaccatc aacaccgtct ccggcgatga cattattaac gccgccgaac acggacaggc 7740 gctggtgatc tccggctcca gcactggcgg cgaagcgggt gatgtcatca ccgtcacact 7800 aaacagtaaa acctacacca ccatgctgga cgcttccggc aactggagcg tcggcgttcc 7860 ggcggctgac gtcactgcgc ttggcagcgg cccgcaaact atcactgcgg caattaccga 7920 cgcggcaggc aacagcgatg acgccagccg cacggtcacc gtgaatctcg ccgcgccaac 7980 cattggtatc aacaccatcg ccaccgatga cgtgattaaa gccacggaaa aaggcgcgga 8040 cctgcaaatc accggcacca gtaatcagcc tgcgggcacc accattacgg tgacgctgaa 8100 cgggcaaaat tacaccgcta ctaccgatag caacggcaac tggagcgcca cggtgccagc 8160 gtcagcggtt agcgcattgg gtgaagccaa ctacacggta acggcaaacg tcactgatac 8220 ggcaggcaac agtaattccg ccagtcataa tgtgctggtc aacagcgcct tgcctgccgt 8280 taccattaac gcggtggcga ctgacgatat tattaacgct gccgaatcgg gaaatgcgca 8340 aaccatcagc gggcaggtga cgggcgcagc gcagggggat acggttaccg ttacgctggg 8400 cggcaacacc tacaccgcca cggtgcagtc taatttaagc tggagtgtgg acgttccggc 8460 ggcggatatt caggcgctgg gcaacggcga cctgacggtt aatgcctcgg tcaccaatgg 8520 cgtcggcaac accggcagcg gctcgcgcga tatcacgatc gacgccaatc tgcctggcct 8580 gcgggtcgat accgtggcgg gcgatgatgt tattaacagc attgagcaca atcaggcgct 8640 ggtgatcacc ggcagcagca gcggattaac ggcgggaacg gcgttaacgg tcgagattaa 8700 caacgttact tatggcgcga cggtattagc cgacggcacg tggagcctcg gtgttccggc 8760 ggtagacgtc agcaactggc cagcgggtac ggtgaatatc acggtaagcg gcaccaacag 8820 tgccggaaca acctccacca ttacccatcc ggttaccgtc gatctggctg gggtcgccat 8880 caccattaac actctctctg gtgatgatgt gatcaacgcc gtcgaaaaag gcgaaacgct 8940 ggtcgtaagc ggcagcacca gcggtgtcga agccgggcag acggtgaccg tcacctttgg 9000 cggcaaaaat tacaccacca cagtggaagc taacggtagc tggacggtga atgtgccgcc 9060 tgccgatctc gctgcgctac cggacggcgc gggcaacgtg caggcgagtg tcagtaatat 9120 taacggcaac agcgcccagg ccgatcgcgc gtatagcgtt gatgccaccg cgccgcttgt 9180 gaccatcaac accatcgcca gcgacgatat ccttaacgtg agcgaagctg gcgcggggat 9240 caccatcagc ggcactacca cggcgcaggc cgggcagacg ctcaccgtca cgctcaataa 9300 caacacgtac cagaccaccg ttctggcgga tggcacctgg agcgtgaatg ttccggcagc 9360 ggatttaagc ggattaaccg ccagcagtta caccgtgacc gccacggtga gcgacaaagc 9420 gggtaacccg gcaagcgccg accacgcgct ggtggtagat atcactgcgc cggatctcac 9480 cattaacacc gtcgcgggcg atgacattat caacgccatc gaacatggtc aggcgttggt 9540 ggtcagcggc accagtacgg gcgcggcggc gggtgatgtg gtaaccgtca cgctgaacgg 9600 taaaaactac accaccacgc tggatgcctc cggtaactgg agcgtgggca ttccggcggc 9660 ggatgtcacg gcgctggcga ccggtagcca gaccatcacc gccagcctga gcgatcgcgc 9720 gggcaacagc gacagcacga ctcacgatgt gaccgttgat cttagcggcc cgacgctgac 9780 cattaacacc gtctccggcg atgacattat caacgccgct gaaatcgttg tggcgcagac 9840 catcagcggt caggtcacgg gaacggcggt tgccgggaat acggtgattg tcaccattgg 9900 cggcaatcaa tataacgcca ccgtgcagtc agatttaagc tggagcgtca gcgtaccggc 9960 gaacgttttg caggcgctgg gtaacggtga actgaccatc agcgcctcgt tgaccaattc 1002 0 cgcaaataat accggcaccg cgacgcacga tatcgtgata gatgccaacc tgccaggtct 1008 0 gcgcgtcgat accgtggcag gcgatgatgt gattaacagc atcgagcaca ctcaggcgtt 1014 0 ggtgatcacc ggtagcagta gcggactggc ggcgggcgcg gcgttgacgg tggttatcaa 1020 0 tagcgtcacc tacggcgcaa cggttttagc ggatggtagc tggagcgttg gtgttccggt 1026 0 ggcagatgtc acaaactggc ctgcggggac ggtcaatatt gccgtctctg gcaccaacac 1032 0 cgccggaacc acaaccagca ttagccatcc ggtcacggtc gatctcgctg ccgtggcgat 1038 0 caccatcaac accctttcca ctgacgatgt gattaacgcc gccgagaaag gctctgattt 1044 0 gcagctctcc ggcaccacct ccggcgtgga agcggggcaa accatcaccg ttatcttcgg 1050 0 cggcaaaagc tacaccacca cggttgccgc ggataatacc tgggggctga cgatccctgc 1056 0 cgtcgatgtt gcaaccttgc cagacggcgc agcaaacgtc caggccagcg tcagcaatgt 1062 0 cgcagggaac agcacccagg caacgcatgc ttacagcgtt gatgccactg cgccctccgt 1068 0 taccatcaac accatcgcca cggacgatat tcttaacgcc gccgaagcgg gatcggcgct 1074 0 gaccatcagc ggcaccagca cggcggaagc cgggcagacg gtgaccgtaa cgctaaacgg 1080 0 cgttaattac agcggcaatg tgcaggcaga cgggagctgg agcgtcagcg taccaaccgg 1086 0 cgatttagct agccttaccg ccagctcgta taccgttaac gcctcggtca gcgacaaagc 1092 0 cagaaattcg gcttcggcaa cgcataatct gacggtggac cttgccgctc cggtcgtcac 1098 0 catcaacacg gtggcgggcg atgacatcat taacgccacg gaacacggac aggcgcagat 1104 0 catcagcggc tcggcaacgg gcgcgactac cggtaatacg gtttccgtga cgattggcac 1110 0 gaccacctat accaccgtgc tggacgccaa cggcaactgg agcatcggcg tgcctgccag 1116 0 cgtgatttcc gcgctggcgc agggcgatgt gaccattacc gctacggtca ccgactccgc 1122 0 aggcaacagc ggcacggcct cgcacactgt caccgtggcg ctcggcgctc cggtgctcgc 1128 0 cattaacacc attgccgtcg atgacatcat caacgccgcg gagaaaggcg cggatctggc 1134 0 gattaccggc accagcaacc agcctgcggg cacgcagatt accgttacgc tcaacgggca 1140 0 aaattacacc accactgccg atgcttccgg taactggagc gtgaccgttc cggcgtcacg 1146 0 ggtgagcgcc ctcggtgaag ccacctacac ggtgaccgca gccgccactg acgccgatgg 1152 0 caacagcggt tccgccagcc ataacgtaca ggttaatacc gcgctgccgg gcgtcaccat 1158 0 taacgtggtg gcaacggacg atattattaa cgccgccgaa gcgggcgtgg aacagaccat 1164 0 cagcgggcag gtgacgggtg cggcggcagg cgacacggtg accgtcacgc tcggcggggc 1170 0 gacttacact gccacggtgc aggcgaattt aagctggagc gtcgatgttc cggcctccgc 1176 0 gctacaggag ttgggcaacg gcgaactgac catttcggct tcggtgacga acagcgtagg 1182 0 caatactggt aacggcacgc gcgaaatcac catagacgcg aatctccccg gtctgcgggt 1188 0 cgacaccgtg gcgggcgatg atgtggttaa tattatcgag cacgggcagg cgctggtgat 1194 0 taccggcagc agctccggtc tggcggcggg cagcaacgtc acgctgacca ttaacgggca 1200 0 aacctatgtt gcggcggtgc tggcggatgg cacctggagc gtcggcgttc cggcggtgga 1206 0 tgtcagcgcc tggcctgcgg gatcggtgac gattgcggcg agcggtagca cctctgccgg 1212 0 aaatccggta agcgttacgc atccggtgac ggtcgatctc tcggcggtgg cggtgagcat 1218 0 caacgccatt accgccgatg atgtgatcaa cgctgccgaa aaaggcgcgg cgttaacgct 1224 0 ctccggcagc acctctggcg ttgaagccgg acaaacggtt accgtcacct ttggcggcaa 1230 0 aacttacagc gccacggtgg ctgcgaatgg ttcctggagc acctcggttc cggcggcaga 1236 0 tatggcggct ctgcgtgatg gcgatgccag cgcacaggcc agcgtcagca atgttaacgg 1242 0 caacagcgcc accacgaccc acgcttacag cgttgatgcc agcgcgccaa cggtgaccat 1248 0 taataccatt gcgggcgatg atattcttaa cgccgccgaa gccggagcgg ctctgaccat 1254 0 caccggcagc agcacggcgg aagcggggca gacggtgacc gtcacgctca atggcacaaa 1260 0 ctacaccggc accgtacaga cggacggcag ctggagcgtc agcgtaccgt cagccgactt 1266 0 aagcaccctg accgccagca actacaccgt gaacgcggcg gtgagcgaca aagccggaaa 1272 0 cccggcctcg gttaatcaca acctgacggt ggatacgtcc gttccggtcg tcaccatcaa 1278 0 cacggtggca ggcgatgatg tgatcaacgc gacggaacac gcccaggcgc agatcatcag 1284 0 cggctccgcc actggagcgg caaccggtag caccgtgacg gtgactatcg gcacaaatac 1290 0 ctttaccacg gtgctggatg ccagcggcaa ctggagcgtc ggcgttccgg caagcgtcgt 1296 0 ctcggcactg gcgaatggca cggtgaccat caatgccagc gtcaccgatg ccggaggaaa 1302 0 cagcggcagc gctacccatc aggtgacggt caataccggg ctgccgacca ttacctttaa 1308 0 cgccatcagc ggcgataaca tcctgaacgc cgatgaaaaa ggccagccgt tgaccatcag 1314 0 cggcggcagt acggggctgg cgacgggcgc gcaggtcacc gtcacgctca acggtcacaa 1320 0 ctacagcgcc accaccgacg catcgggcaa ctggacctta accgtgccgg tgagcgatct 1326 0 ggcggcatta ggtcaggcca actatacggt cagcgccagc gccaccagtg cagcaggcaa 1332 0 caccgccagc agccaggcga atttactggt cgacagcggc ctgccggacg tcaccatcaa 1338 0 caccgtggca ggcgacgata ttatcaacgc cgccgaagcg ggggccgatc aaaccatcag 1344 0 cggggtggtg actcgcgccg ccgctggcga tacggtcacc gtgacgctgg gcgggaacac 1350 0 ttacaccgct acggtacaga gcaacttaag ctggagcgtc agcgttccga cagccgatct 1356 0 ccaggcgttg ggcaatggtg atttgaccat taccgcctcg gtcaccaacg ctaatggcaa 1362 0 caccgggagc ggcacgcggg atatcaccat tgatgccaac ctgccggggc tgcgcgtaga 1368 0 taccgtggcg ggcgatgata tcgtcaacag catcgagcac gggcaggcgc tggtgatcac 1374 0 cggcggcagt agcggcctga atgcaggtgc tgtgctgacg gttaccatca acagtgtggc 1380 0 gtattccgcc acggtgcagg cggacggaag ctggagcgtt ggcattccgg cggcaaacgt 1386 0 cagcgcctgg cctgcggggc cgttaaccgt ggaggtagac gggcaaagca gcgccaataa 1392 0 cccagtcagc gtcagccatc cgttcaccgt cgatttaacg gcggtggcaa tcagcatcaa 1398 0 caccgttgcc agcgacgacg tgattaacgc cgcagaaaaa ggcaccaatc tgactctttc 1404 0 cggcagtacc agcgggattg agagcgggca aaccgtcacc gtcacttttg gcggtaaaac 1410 0 ctacactgca agcgtcgccg ccaacgggag ctggagtgta aacgttccgg cggcagatct 1416 0 ggcaactctg ccagagggcg cggcgaatgt gcaggccagc gttagcagcg cgagcggtaa 1422 0 cagtgcctcg gcgacccatg cgtatagcgt tgacgccagc gcgccgacgc tcaccattaa 1428 0 caccatcgcc agcgacgata tccttaacgc cgcagaagcc ggaagcccgc tcaccatcag 1434 0 cggcaccagc accgccgaaa ccgggcagac ggtgaccgtc acccttaacg gcgcaaccta 1440 0 caccggcact gtgcaggcgg acggtagctg gagcgtcagc gttcccactt cagccctggg 1446 0 cgcgctcaac gcaagcaatt acaccgtcag cgccacggtc aatgacaaag cgggcaaccc 1452 0 cggcagcgcc agccataatc tggcggtaga caccaccgcg ccggttctca ccattaacac 1458 0 cgtggcgggc gatgacatca tcaacgatgc cgaacatgcg caggcgctgg tgatctccgg 1464 0 caccagtagc ggcggggaag cgggcgatgt ggtgagcgtt gtgctcaacg gcaaaaccta 1470 0 caccaccacc ctggatgcct ccggcaactg gagcgttggc gttccggcgg cagatgttac 1476 0 ggcgctgggt agcggtgcgc agaccatcac cgccagcgtc agcgatcggg caggcaacag 1482 0 cgacgacgcc agccgcaccg tgaccgtcag cctcagcgcg ccagtgatta gcatcaacac 1488 0 catcgcgggc gatgatgtga tcaacgcgac ggaaaaagga tctgatctgg cgctttctgg 1494 0 caccagcgat cagcctgcgg gtacggcgat caccgtcacc ctgaacggac aaaactacag 1500 0 cgccaccacg gatgcctccg gcaactggag tgttaccgtg cctgcctcgg cggtcagtgc 1506 0 gctgggcgaa gcgacctaca gcgtgacggc gagcgtcacc aatgctcagg gtaacagcag 1512 0 caccgccagc cataacgtgc aggttaatac cgcgctgccg ggcatcacca ttaatccggt 1518 0 ggcgacggac gatattatca acgcttcaga ggcaggcagc gcgcaaacta tcagcggcca 1524 0 ggtaaccggt gcggcggcgg gcagcaccgt caccgttgaa ctgggcggta aaacttacac 1530 0 cgccaccgtc caggctgatt taagctggaa tgtgagcgta cctgccgccg actggcaggc 1536 0 tctgggtaac ggtgagttaa cggttaatgc ctcggtgacc aacgccgttg gcaacaccgg 1542 0 tagcggcacg cgcgatatca ccatcgatgc cagtctgcct ggcctgcggg tggataccgt 1548 0 cgcgggtgat gatgtggtca atatcatcga acacgctcag gcgcaggtga tcaccggcag 1554 0 cagctccggc tttgccgcag gcacggcgtt gacggtggtg attaacaacc aaacttacgc 1560 0 cgccacggtg ttggcgaacg gtagctggag cgtcggcgtt cctgcgacgg atgtcagtaa 1566 0 ctggcctgcg ggaacgctga atattaccgt tagcggggcg aacagtgccg gaacgcaaac 1572 0 cagcattacc catccgctga ctgttgatct caccgccgtc gccatcagca tgaacagcat 1578 0 caccagcgat gatgcgatta acgccgccga aaaaggcgcg gcgttaacgc tctccggcag 1584 0 cacgtccggc gtcgaagcgg ggcaaaccgt caccgtcacc tttggcggca aaacctacac 1590 0 caccacggtg gcggcaaacg gtagctggag caccaccgtt ccggcggcgg atttggcggc 1596 0 cctgcgtgat ggcgatgcca gcgcccaggt gcgggtgact aacgtcaacg gcaacagcgc 1602 0 cacagcaacg cacgaataca gcgtcgatag cgccgcgcca acggtgacca tcaacaccat 1608 0 tgccagcgat aacatcatca acgccagcga agcggcggcg ggcgtaacgg tgtccggcac 1614 0 cagcaccgcg caaaccgggc agacgctcac cgtcacgctt aacggcacta actaccagac 1620 0 cacggtgcag acagacggca gctggagttt aacgctgccc gccagcgact taaccgcact 1626 0 tgctaataac ggctacaccc tgaccgccac ggtcagcgat ctggcgggta accttggcag 1632 0 cgccagcaaa ggcgtgaccg tcgataccac tgcgccggtg atcagtttta acaccgtggc 1638 0 gggcgatgat gtgattaaca acgtcgaaca cattcaggcg cagattatca gcggcaccgc 1644 0 cacgggcgcg gtggcgggcg accgcctggt ggtgaccatc gccgggcagc agtatgtcac 1650 0 cagcaccgat gccagcggca actggagcgt cggcgtgcct gccagcgtga tttccggcct 1656 0 tgcggatggc acggtgacca tcagcgccac cattaccgat agcgcaggca acagcagcac 1662 0 gcagacgcac aacgtacagg tgaacacggc ggcagtgtcg ctctcggtca gcactatcag 1668 0 cggcgataac cttattaacg ccgccgaagc gggcagtgcg ctgaccctga gcggcactgg 1674 0 cactaatttc gcgacaggta cagtggtgac cgtgttgctt aacggcaaag gctacagcgc 1680 0 caccattcag agcaacggga gctggagcgt gaacgtgcct gcggcggatg ttgcggcact 1686 0 cagtgatggc accagctaca cggttagcgc ctccgctcag gacagtgccg gaaacggcaa 1692 0 cagcagcacg cagacgcaca acgtacaggt gaacacggcg gcagtgtcgc tctcggtcag 1698 0 cactatcagc ggcgataacc ttattaacgc cgccgaagcg ggcagtgcgc tgaccctgag 1704 0 cggcactggc actaatttcg cgacaggtac agtggtgacc gtgttgctta acggcaaagg 1710 0 ctacagcgcc accattcaga gcaacgggag ctggagcgtg aacgtgcctg cggcggatgt 1716 0 tgcggcactc agtgatggca ccagctacac ggttagcgcc tccgctcagg acagtgccgg 1722 0 aaacagcgcc acggcctcgc gcagcgtggc ggtggatctc accgcgccgg ttatcagcat 1728 0 taacaccgtt tcgacggacg accgcctcaa cgccgccgaa cagcagcagc cgttaaccct 1734 0 taacggctcg accagcgcgg aagtggggca gacggtcacc gtcacctttg gcggcaaaac 1740 0 ctataccgcc acggttgccg ccaatggtac ctgggcgctg aacgtgcctg cggtggatct 1746 0 ggccgcgctc gggcagggcg cgcagaccat taccgccagc gtgaacgatc gcgccggtaa 1752 0 ccccggacag gccacgcacg ccctgaccgt cgataccgtt gcgccaacgg tcaccatcgc 1758 0 cacggtggcg ggtgacgata ttatcaacaa cgccgagcag cttgccgggc agaccattag 1764 0 cggcaccacc accgccgaag tgggccagac ggtgaccgtt acctttaacg ggcaaacctg 1770 0 gagcgcaacg gttggcagcg gcggaagctg gtcggtgttt attccggcgc agcagtttgc 1776 0 cggattaagc gacggcagct acaccattag cgcgacggtt agcgatcagg ccggaaaccc 1782 0 cggcagcgcc agccgtggcg tgacgctgaa cggcgatgta cctactgtca ccatcaacac 1788 0 ctttgcgggc gacgatgtgg tgaatgcagc ggaacacggc tcatcgctgg tgatcagcgg 1794 0 caccaccacc gcgcccgtcg ggcagacgct gaccctgacc ttaaacggca aaacctacac 1800 0 caccacggtg cagacgggcg gtagctggag ctacaccctc ggcagcgccg atgtcaccgc 1806 0 gctggcggac ggcaacgcct acgtgattaa cgcctcggtg agcaatgcca ttggcaacac 1812 0 cggtagcagt aatcacacca ttaccgtcga tctcagcgct ccggcgatgg gcattaatat 1818 0 cgattccctg caagccgaca ctggccttag cgccagcgac tttatcacca gcgtcagtcc 1824 0 ggtagtggtc aacggctcgc tcaccgccgc gcttgccagt aacgagacgg cgcaaataag 1830 0 tatcgacggc ggcacaacct ggaccacgct taccgttacc ggcacgacct ggcgctataa 1836 0 cgacagccgc acgctgaccg atggcaacta tctctatcag gtgcgggtga ttgacgcagc 1842 0 gggcaacgtt ggcgcgaccg acagccagaa tgtggtgatc gacactaccg cgccagatcc 1848 0 cgcggtgaaa accatcgcca tcagcgcgat caccaccgat atgggcttga tcactaacga 1854 0 ttttgtcacc agcgacacga cgcttgcggt gagcggcacg ctgggggcga cgctttctgc 1860 0 cggtgagttc gcgcaaatca gcctcgacgg cggcgtcacc tggactacgt taaccgtcgt 1866 0 tggcaccagc tggagctatg ccgatggtca cacgcttact gacggcacct ggaactacac 1872 0 ggtgcgggtg gtggatctgg cggggaacgt tgggcagacc gcaacgcaaa acgtggtggt 1878 0 cgacaccacc agcccggaag cggcgaaaag tatcaccatt accggtatca gcgatgacac 1884 0 cggaaccagc agcagcgatt ttattaccag cgacaccacg cttaccgtgc gcggcgtatt 1890 0 gggcgcggcg ctcggcgcta atgagttcgc gcaaatcagt accgacaacg gcgcaacctg 1896 0 ggtgaacgtg accgtcgccg cagacagcct gaactggagt tacgttgacg gacgaaccct 1902 0 caccaacggc accaccacct ggcaggtgcg ggtggtcgat ctggcgggca acgttggcgc 1908 0 aacgagcagc cagtcggcgc tgatcgatac cgttaacccg gcgcaggtgc tcaccatcgc 1914 0 cagcatcagc accgacacgg ggagttcggc aactgacttt atcaccagcg acaccatgct 1920 0 cacgctgacc ggttcgctgg gggcggggct tgccagcggc gaagtggcgc agattagcct 1926 0 tgatagcggc gcgacctgga caacgctcac caccaacggt acacagtgga cttacaccga 1932 0 cagccgcacg ctgaccgacg gcagctacgt ttatcaggtg cgggtgctgg atctggcggg 1938 0 gaacaccggc ccggtggtgt cgaaaacggt ggtggtcgat acgattaacc ccaccgccac 1944 0 accaacgatt gtgtcgtata ccgatgatgt cgggcagcgg caggggacat taagcagttc 1950 0 gcaggccacc gacgacacta cgccgctgct gaacggtgta ctttccgcgc cgcttgccag 1956 0 cggtgaagtg gtttacctct accgtaacgg gctgctgtta ggggcggtga cgatggtcgg 1962 0 cgctctgaac tggacctaca gcgacagcgg gctggtgagc ggtgcctata cctacagcgc 1968 0 gcgagtggtg gatttggcgg ggaatatcac ctcctccagt gattttgtcc tgacggtcga 1974 0 tacctctatt ccgaccacgc tggcgcaaat caccagccag accacgcgcg atactacgcc 1980 0 gattattagc ggggtgatca ccgccgcgct tgccagtggg cagtatgttg aagtggtgat 1986 0 caacggcaaa acctacacct ctgaaccggg cggcgcggta gtggtcgatc cggcgcacaa 1992 0 cacctggtat gtacagttgc cggataccga tgcgctgaca gtttccgcga ccgcctatac 1998 0 cgttactgcg caggtaaaaa gttcggcggg taacggcaat aacgccaata ttagcaacgg 2004 0 cacggtgacg gttaacgcgg cgattgatta cacaccgacc tggactaccg ccagcaaaac 2010 0 caccgcctgg gggctgacct acggcctcga ctcgcacggg atgtggacgg tgctggcaaa 2016 0 ccagcaggta atgcaatcga ctgacccact cacctggtcg aagaccgcgc tgacgctgta 2022 0 tcagagcggc aacaactacg ccaccagctc cattgccgat tacgaccgta acggcacggg 2028 0 cgatctgttt atcacccgtg atgactacgg tacgggctat attaacggct ttaccaataa 2034 0 cggcgatggc accttttcca gcgctattca ggtcaccgtc ggcaccctga cgtggtacgg 2040 0 ctcgattgtg gcatttgata aagagggcga cggctatctc gacttctgga ttggtgacgc 2046 0 tggcgggccg gactccaaca ccttcctgtg gaacaacgca ggcacgctgg taggcaactc 2052 0 caccacgtcg aacagcggcg gtagcgccac ggtgggcggg gcggtgacgg ggtatctttc 2058 0 gctcaacgaa ggttctggcg tcgatctgaa caatgacggc aggatcgacc tggttcagca 2064 0 cacctataac ctgaacaact attacacgct gtcttcgctc atcaaccagg ggaatgggac 2070 0 gtttgtctgg gggcagaaca ccaccaatac cttcctgagc ggggcgggca gtggcgctat 2076 0 gagcagcagc gtttccatga cctgggccga tttcgatggt gacggcgata tggatctctt 2082 0 cctgcccgcc agccagggaa gagctaacta cggctcgctg ttattcaaca ccaacggcgt 2088 0 actgggttgc ccggtggcgg tgggcgcaac ggcaaccacc tacgccagcc agtttagcct 2094 0 ggcggtggac tggaaccacg acggcctgat ggatatcgcc cgtatcgccc agaccgggca 2100 0 gtcgtatctt tatactaacg tcagcaacgc cagcaactgg acgcaatcgg ccctcggcgg 2106 0 cagccagagc ggtaccacca gcggcgtggc ggcaatggac tacgactggg acggcgcggt 2112 0 ggatgtgctg gtgtccaaac agtcgggcag cgtgttcctg agccgcaaca ccaacacggt 2118 0 gagctacggc acttcgctac acctgcgcat caccgatccc aacggcatta acgtctatta 2124 0 cggcaatacc gtgaagctgt acaactcggc gggagtgctg gtcgccacgc aaatcatcaa 2130 0 cccgcagtcg ggtatggggg ttaacgacac ctcggcgctg gtcaacttct acgggctgaa 2136 0 tgccggagaa acctacaacg cggtgctgat caaatccacc ggcaccaccg ccagcaatat 2142 0 cgaccagacg gtcaacacca gctggggcgg tttacaggcc accgatgcca ctcacgctta 2148 0 cgatctcagc gctgaagcgg gtaccgcgag caacaacggc aagttcgtcg gcaccggcta 2154 0 taacgacacc ttcttcgcca ccgcaggcac cgacacttac gacggttccg gcggctgggt 2160 0 gtacagctcc ggcaccggaa cgtggctggc gaacggcggg atggacgtgg ttgatttccg 2166 0 gctttcgacg gtgggcgtga cggctaactt aagcagcact gccgcgcagg ccaccggttt 2172 0 taacacctcg acatttacca atatcgaagg catttccggc tcgaatttta acgacattct 2178 0 gaccggcagc agcggcgata accaactgga agggcgcggc ggcaacgaca cgctcaacat 2184 0 cggcaacggc ggccacgaca ccttgctcta taaactgctc aacgccagcg acgccactgg 2190 0 cggcaacggc tcagacgtgg tgaatggctt tacggtaggg acatgggaag gcaccgccga 2196 0 caccgatcgc attgatattc gtgaactgtt acagggcagc ggctacaccg gcaacggcaa 2202 0 agccagctac gtcaacggcg tggcaacgct ggatgcgcag gccggaaaca tcggtgactt 2208 0 tgtcaaagtc acccagagcg gcagcgacac catcgtgcag atcgaccgcg acggcacggg 2214 0 cggcactttt gcgacaacta acgtggtcac gctgacgggc gtgcacaccg acctcgccac 2220 0 cttgctggcg aatcatcagt tgatggtggt gtagataatg aaaaaaaatg cccagtccgt 2226 0 ggaagcctgg ctggaggcga tgatcgccgt ggcgcgctat tatcggctcg atttttctca 2232 0 ggagaatgtg cgcgcgaccg tcaactggga gcgcgacagt aagcgggagg agttactcac 2238 0 cgacatggcg cggcagttag ggatggggtt gcggttggtg gagttttccg ccgattcgct 2244 0 taacccctgg cgtctgccgc tgatcgcggt gtttgataat cagcagattg gcgtgatcac 2250 0 ccgtcgcgac aatcatgaca atatcagcgt tcagttcagc ggtgacgaag ggctggaaac 2256 0 tacacttaac gtcgcggata ttgaagataa aatcgtcgaa ctggcgctgc tgcgccctct 2262 0 cagcgccatc cctgacgcgc gggtggatga ctatattcgc ccgtatcagg cgaactggtt 2268 0 ctggagtctt tcgctaaaag actggcggcg ctacggcgat attatgctgg cgtcactggt 2274 0 ggcgaacgtg ctggcgctgg cggcgatgat tttctcgatg caggtttacg atcgggtggt 2280 0 tccggcgcaa tcgtacccga cgctatgggt gcttttcgcc ggggtgatga tggcgatcct 2286 0 gtttgagttc tgtatgcgca tggtgcgtac gcatctatct gatgtgatcg gaaagcgggc 2292 0 agacctgcgt atttcggatc gcgtttttgg tcatgcgcta cggctgaaaa acaacgtgcg 2298 0 atcgaaatcc accggatcgt ttatctcgca gatccgcgaa ctggaatcag tgcgggagct 2304 0 tattacgtcc accaccatcg gcgcggtggc ggacctgcca ttcttcctgc tgtttgtctt 2310 0 tattttgtgg atgatcggcg gctggctggt gctggtggtt ttgctggcgc tgccgttgct 2316 0 ggtgatcccc ggcctgctgg tgcaacgccc gctggcgcgg ctggcgaacg aaggaatgcg 2322 0 cgagtcagcg gtacgcaacg ctacgctggt ggaagccgtg cagtcgattg aagatattaa 2328 0 actgctgcgc gccgaacagc gttttcagaa tcagtggaac cacaccaacg acgtggcctc 2334 0 gtccatcagc atgaagcaac gttttctcac cgggctgctg ctcacctgga cccaggaagt 2340 0 gcagtccatc gtctacgtgg tggtgctgct ggtgggctgc tttatggtga tgaacggcga 2346 0 catgaccacc ggcgcgctgg tcgggacgac gatcctggct tcgcgcacca ttgcgccgct 2352 0 gtcgcagata tccggcgtgc tctcgcgctg gcagcaggcg aaagtagcac gtaacggcct 2358 0 tgatgaactg atgaagcgcc cggtggatca gccggaacac ggcaaactgg tgcataaagc 2364 0 ggtgctgcac ggtaattatc agttcagcaa cgcggtgttt tattacgacg aagaagagaa 2370 0 gattgccgat gtagcgattg gcaaactcaa cattcaggct ggtgagaaaa tcgccattct 2376 0 cgggcgcaac ggcgcgggta aatcgacgct actgcaaatg ctcgccggaa tgcgtatcgc 2382 0 ccagcagggg caggtgttgc tggataacat cagtatcggg cagcttgatc cggcagatct 2388 0 gcggcgagac atggggctac tcagccagac cgggcgactg ttctttggtt cgctgcggga 2394 0 aaacctcacc atggggatgc cggaagccag cgatgaagat atcgaacgcg cgttaaccct 2400 0 cagcggagcg ctgccctttg tgcagaagca gaaaaacggc ctcaactaca tgattcagga 2406 0 agggggattt ggcctctctg gtggtcagcg gcaaacgctg ctgctggcgc ggctactcat 2412 0 ctctcagccg aatatcgtcc tgctcgacga acccagcgcc tcactggacg aaatggcaga 2418 0 agcgtattta atcgaacaac tgaaacagtg gattgggcat cgcacgctga ttatcgccac 2424 0 tcaccgcacg gcgatgctgc aactggtgga taggataatc gtgatggatc aggggcggat 2430 0 tgtgatggac ggcgcgaaag aggccatttt gcgtgaacag ggcgagccca cagcgcgacg 2436 0 ggtggtgttg caggagaaga ataaggggtc tgcggcatga acggacaact gcaatataac 2442 0 cgtggtctga ctgaaccccg cctgccgcgt tcggcgctgg cggtacgcgt taccgctgtg 2448 0 atgctgctct gttttctcgg ctgggcgtgg tacttccagc ttgatgaagt caccaccggc 2454 0 agcggcacgg tagaaccttc cgggcgcgaa caggtggtgc agtcgctgga aggcggaatt 2460 0 ctgtatcatc tcgacgtgaa agttggcgat attgtcgaac agggccagcc gctggcgcag 2466 0 cttaaccgca ccaaaacgga atccgacgtc caggaagcga tgtcgcggct gtacgcggcg 2472 0 ctggcaacct cggcgcggct gcgggcggaa gtgagcaata aaccgctggt cttccctgac 2478 0 gaactgaata aattccccga acttatcgag tcggaaacgg cgttgtacaa cactcgccgc 2484 0 gacgggttga acaaagccac caccgggctg acgcagggga ttagcctggt caatcgcgaa 2490 0 ctggcgatga cccagccgct ggtaaaacag ggggcagcga gcagcgtcga agtactgcgc 2496 0 ctgcaacgcc aggccaatga actggaaaac aaactcagcg acgtgcgcac gcaatactac 2502 0 gttcaggcgc gcgaagagtt agcaaaagcc aatgcggaag tggaaaccca gcgttcggtg 2508 0 atccgtggac gggaagactc tctcaccagg ctcaacttta ccgcgccggt gcgaggcatt 2514 0 gttcaggata ttgatgtcac cacggttggc ggcgtcatcg cccccggtgg taaactgatg 2520 0 accatcgtgc cgctggatga gcaactgctg attgaggcaa aaatctcccc gcgcgatgtg 2526 0 gcgtttatcc acccggggca aaaatcgctg gtgaaaataa ctgcctacga ttactccatc 2532 0 tacggcggcc tgccgggaga agtggcggtg atatcaccag acaccgtgca ggatgaagtg 2538 0 cggcgcgatg tttattacta tcgggtgtac attcgcactt tcagcaacca tctggaaaac 2544 0 aaaagcaaac agcagtttcc gatattcccc ggt 2547 3 <210> 1056 <211> 452 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(308..1663) <400> 1056 Met Ala Arg Phe Gln Phe Lys Asn Arg Lys Asn Asn Gly Leu Ile Phe 1 5 10 15 Phe Ile Ser Phe Met Val Met Gly Glu Ala Ala Ile Ala Ala Pro Leu 20 25 30 Pro Gln Trp Ala Asn Ala Pro Ala Val Thr Pro Val Ala Gln Leu Ser 35 40 45 Leu Gln Glu Ser Ile Leu Arg Ala Phe Ala Arg Asn Pro Gly Val Thr 50 55 60 Gln Gln Ala Ala Gln Ile Gly Ile Gly Glu Ala Gln Ile Asp Glu Ala 65 70 75 80 Lys Ser Ala Trp Tyr Pro His Val Gly Leu Thr Gly Asn Ala Gly Pro 85 90 95 Ser Arg Gln Thr Asp Ser Ser Gly Arg Leu Asp Asn Asn Val Ser Tyr 100 105 110 Gly Ile Thr Leu Thr Gln Leu Val Tyr Asp Phe Gly Lys Thr Asn Asn 115 120 125 Asp Ile Asn Leu Gln Thr Ala Ala Arg Asp Ser Tyr Arg Phe Lys Leu 130 135 140 Met Ala Thr Leu Thr Asp Val Ala Glu Lys Thr Ala Thr Ala Tyr Met 145 150 155 160 Glu Val Ser Arg Tyr Gln Ala Leu Cys Asp Ala Ala Gln Arg Asn Ile 165 170 175 His Ser Leu Glu Asn Val Tyr Asn Met Ala Ala Leu Arg Ala Asn Ala 180 185 190 Gly Leu Asn Ser Ser Ser Asp Glu Leu Gln Ala Gln Thr Arg Ile Ala 195 200 205 Gly Met Arg Ser Thr Leu Glu Gln Tyr Gln Ala Gln Met Ala Ser Ala 210 215 220 Lys Ala Gln Leu Ala Val Leu Thr Gly Val Gln Pro Glu Ala Ile Ala 225 230 235 240 Ala Pro Pro Ala Glu Leu Ala Glu Gln Pro Val Ser Leu Lys Asn Ile 245 250 255 Asp Tyr Gln Ser Ile Pro Leu Val Leu Ala Ala Glu Asn Leu Arg Gln 260 265 270 Ser Ala Gln Tyr Gly Val Glu Lys Thr Lys Ala Gln Tyr Trp Pro Thr 275 280 285 Leu Ser Ile Gln Gly Gly Lys Thr Arg Tyr Gln Thr Ser Asp Arg Ser 290 295 300 Tyr Trp Asp Asp Gln Leu Gln Leu Asn Val Asn Ala Pro Leu Tyr Gln 305 310 315 320 Gly Gly Ala Val Ser Ala Gln Val Gln Gln Ala Glu Gly Gln Gln Lys 325 330 335 Ile Ser Ala Ser Gln Val Glu Gln Ala Lys Leu Asp Val Leu Gln Arg 340 345 350 Ala Ser Val Ala Tyr Ala Asn Trp Thr Gly Ala Arg Gly Arg Glu Glu 355 360 365 Ala Gly Leu Ala Gln Ser Glu Ser Ala His Lys Thr Arg Asp Val Tyr 370 375 380 Gln Asn Glu Tyr Lys Leu Gly Lys Arg Ser Leu Asn Asp Leu Leu Thr 385 390 395 400 Val Glu Gln Asp Val Phe Gln Ala Gln Ser Ala Glu Ile Asn Ala Asn 405 410 415 Tyr Asp Gly Trp Val Ala Ala Val Asn Tyr Ala Ala Ala Val Asn Asn 420 425 430 Leu Ile Pro Leu Ala Gly Ile Lys Gln Gly Leu Tyr Asn Asp Leu Pro 435 440 445 Asp Leu Lys * 450 <210> 1057 <211> 1462 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1766..6151) <400> 1057 Met Ser Leu Ile Ile Asp Val Ile Ser Arg Lys Thr Ser Val Lys Gln 1 5 10 15 Thr Leu Ile Asn Pro Gly Asp Val Thr Val Val Ile Tyr Glu Pro Ser 20 25 30 Val Val Gln Val His Ala Gln Ala Ser Ala Val Ala Arg Tyr Val Arg 35 40 45 Glu Gly Asn Asp Leu Leu Ile Tyr Met Gln Asp Gly Thr Val Ile Arg 50 55 60 Cys Asn Gly Tyr Phe Leu Gln Ala Ala Asn Thr Ala Glu Gln Ser Glu 65 70 75 80 Leu Val Phe Ala Asp Gly Gln Gln Leu Thr His Ile Thr Phe Ala Asp 85 90 95 Thr Ala Ala Gly Gly Leu Ala Pro Val Glu Leu Thr Ala Gln Thr Thr 100 105 110 Ala Ile Glu Ser Ile Ala Pro Phe Leu Asp Thr Val Ala Gln Thr Ser 115 120 125 Ala Phe Pro Trp Gly Trp Leu Ala Gly Ala Ala Val Gly Gly Gly Ala 130 135 140 Leu Gly Ala Leu Leu Ala Ser Gly Gly Asp Gly Asp Ser Lys Thr Glu 145 150 155 160 Val Ile Asn Asn Pro Thr Pro Pro Ala Glu Pro Gly Asn Ala Thr Pro 165 170 175 Ser Phe Leu Val Thr Asp Asn Gln Gly Asp Gln Arg Gly Ile Leu Ala 180 185 190 Thr Asn Asp Ile Thr Asp Asp Thr Thr Pro Thr Phe Ser Gly Ser Gly 195 200 205 Gln Ala Gly Ala Thr Ile Gln Ile Lys Asp Ser Asn Gly Asn Thr Ile 210 215 220 Ala Ser Thr Gln Val Asp Asn Asn Gly His Trp Ser Val Ser Leu Pro 225 230 235 240 Thr Gln Ser Ala Gly Glu His Thr Trp Ser Val Val Gln Ile Val Gly 245 250 255 Ser Thr Ile Thr Asp Ala Gly Ser Ile Thr Leu Thr Ile Asp Asn Ser 260 265 270 Gln Ala Ser Val Gln Val Ala Thr Thr Ala Gly Asp Asn Ile Ile Asn 275 280 285 Ala Ser Glu Gln Ala Ala Gly Phe Thr Leu Ser Gly Thr Ser Ser His 290 295 300 Leu Ala Gln Gly Thr Glu Leu Thr Val Thr Leu Asn Gly Lys Thr Tyr 305 310 315 320 Thr Thr Ser Val Gly Ala Asn Gly Ala Trp Ser Val Gln Val Pro Thr 325 330 335 Ala Asp Ala Gln Ala Leu Gly Glu Gly Asn Gln Ala Val Leu Val Ser 340 345 350 Gly Lys Asp Ala Thr Gly Asn Thr Val Thr Gly Ala Gln Leu Leu Thr 355 360 365 Val Asp Thr Gln Pro Pro Thr Leu Ala Ile Asn Thr Ile Ala Gln Asp 370 375 380 Asn Ile Ile Ser Ala Ala Glu His Asn Val Ala Leu Val Leu Ser Gly 385 390 395 400 Thr Ser Asn Ala Glu Ala Gly Gln Thr Val Thr Leu Thr Val Asn Gly 405 410 415 Lys Ser His Thr Ala Thr Val Gly Ser Asp Gly Thr Trp Gln Val Thr 420 425 430 Leu Pro Ala Thr Glu Val Gln Ala Leu Ala Glu Gly Asn Tyr Ala Val 435 440 445 Asn Ala Ser Val Ser Asp Arg Ala Gly Asn Thr Thr Ser His Ser Ala 450 455 460 Asn Phe Thr Val Asp Thr Ser Ala Pro Val Val Ser Val Asn Thr Val 465 470 475 480 Ala Gly Asp Asp Ile Leu Asn Asn Ala Glu Gln Ala Val Ala Gln Ile 485 490 495 Ile Ser Gly Gln Val Ser Gly Ala Ser Pro Gly Asp Thr Val Thr Val 500 505 510 Lys Leu Gly Thr His Val Leu Thr Gly Ile Val Leu Ala Asp Gly Ser 515 520 525 Trp Asn Val Ala Leu Asp Pro Ala Val Thr Arg Thr Leu Asp Arg Gly 530 535 540 Ala Asn Thr Ile Phe Val Thr Val Thr Asp Ala Ala Gly Asn Thr Gly 545 550 555 560 Ala Ala Ser Arg Ala Ile Thr Leu Val Gly Val Ser Pro Leu Ile Thr 565 570 575 Ile Asn Thr Val Ser Gly Asp Asp Ile Ile Ser Gly Ala Glu Lys Gly 580 585 590 Ala Pro Leu Thr Leu Thr Gly Ser Thr Gln Gln Ala Glu Thr Gly Gln 595 600 605 Thr Val Thr Val Thr Leu Ala Gly Gln Ser Phe Thr Thr Thr Val Gln 610 615 620 Ala Asp Gly Ser Trp Ser Leu Thr Val Pro Ala Ala Ala Met Gly Asn 625 630 635 640 Leu Pro Asp Gly Ala Val Ala Ile Thr Ala Ser Val Thr Asp Leu Ser 645 650 655 Gly Asn Thr Gly Asn Thr Ser Arg Thr Ile Thr Val Asp Ser Gln Ala 660 665 670 Pro Ala Leu Ser Ile Asp Pro Leu Thr Ala Asp Asn Ile Ile Asn Ala 675 680 685 Ala Glu Ser Gly Gln Asp Leu Pro Ile Thr Gly Thr Thr Asp Ala Gln 690 695 700 Pro Gly Gln Thr Val Thr Val Thr Leu Asn Gly Gln Thr Tyr Gln Gly 705 710 715 720 Val Val Gln Pro Asp Gly Thr Trp Ser Val Thr Val Pro Ala Ala Asn 725 730 735 Val Gly Ala Leu Ala Asp Gly Asn Ala Thr Val Thr Ala Ser Val Asn 740 745 750 Asp Val Ala Gly Asn Pro Ser Ser Val Ser Arg Val Ala Leu Val Asp 755 760 765 Ala Thr Pro Pro Val Val Thr Ile Asn Pro Val Ala Thr Asp Asn Val 770 775 780 Ile Asn Thr Pro Glu His Ala Gln Ala Gln Ile Ile Ser Gly Thr Val 785 790 795 800 Thr Gly Ala Gln Ala Gly Asp Ile Val Thr Val Thr Leu Asn Asn Val 805 810 815 Asp Tyr Thr Thr Val Val Asp Gly Ser Gly Asn Trp Ser Leu Gly Val 820 825 830 Pro Ala Ser Val Val Ser Gly Leu Ala Asp Gly Ser Tyr Pro Val Ser 835 840 845 Val Ser Val Thr Asp Lys Ala Gly Asn Thr Gly Ser Gln Ser Leu Thr 850 855 860 Val Thr Val Asn Thr Ala Ala Pro Leu Ile Gly Ile Asn Ser Ile Ala 865 870 875 880 Gly Asp Asp Val Ile Asn Ala Ser Glu Lys Gly Ala Asp Leu Gln Ile 885 890 895 Thr Gly Thr Ser Asp Gln Pro Val Asn Thr Ala Ile Thr Val Thr Leu 900 905 910 Asn Gly Gln Asn Tyr Thr Thr Thr Thr Asp Ala Ser Gly Asn Trp Ser 915 920 925 Val Thr Val Pro Ala Ser Ala Val Thr Ala Leu Gly Gln Ala Asn Tyr 930 935 940 Thr Val Thr Ala Ala Val Thr Ser Asp Ile Gly Asn Ser Ala Thr Ala 945 950 955 960 Ser His Asn Val Leu Val Asp Ser Ala Leu Pro Gly Val Thr Ile Asn 965 970 975 Pro Val Ala Thr Asp Asp Ile Ile Asn Ala Ala Glu Ala Gly Val Ala 980 985 990 Gln Thr Ile Ser Gly Gln Val Thr Gly Ala Glu Asp Gly Asp Thr Val 995 1000 1005 Thr Ile Thr Leu Gly Gly Asn Thr Tyr Thr Ala Thr Val Gly Ser Asn 1010 1015 1020 Leu Thr Trp Ser Val Asp Val Pro Ala Ala Asp Ile Gln Ala Leu Gly 1025 1030 1035 1040 Asn Gly Asp Leu Thr Val Asn Ala Ser Val Thr Asn Gln Asn Gly Asn 1045 1050 1055 Thr Gly Ser Gly Thr Arg Asp Ile Thr Ile Asp Ala Asn Leu Pro Gly 1060 1065 1070 Leu Arg Val Asp Thr Val Ala Gly Asp Asp Val Val Asn Ile Ile Glu 1075 1080 1085 His Gly Gln Ala Leu Val Val Thr Gly Ser Ser Ser Gly Leu Ala Glu 1090 1095 1100 Ser Thr Pro Leu Thr Val Thr Ile Asn Asn Val Glu Tyr Thr Thr Ala 1105 1110 1115 1120 Val Gln Ala Asp Gly Ser Trp Ser Val Gly Val Thr Ala Ala Gln Val 1125 1130 1135 Ser Ala Trp Pro Ala Gly Thr Val Asn Ile Ala Val Ser Gly Glu Ser 1140 1145 1150 Ser Ala Gly Asn Ser Val Ser Ile Thr His Pro Val Thr Val Asp Leu 1155 1160 1165 Thr Pro Ala Ala Ile Thr Ile Asn Thr Ile Ala Thr Asp Asp Val Ile 1170 1175 1180 Asn Ala Ala Glu Lys Gly Ala Asp Leu Thr Leu Ser Gly Thr Thr Thr 1185 1190 1195 1200 Asn Val Glu Pro Gly Gln Thr Val Thr Val Thr Phe Gly Gly Lys Asn 1205 1210 1215 Tyr Thr Ala Ser Val Ala Ser Asp Gly Ser Trp Thr Ala Thr Val Pro 1220 1225 1230 Ala Ala Asp Leu Ala Ser Leu Pro Glu Gly Ser Ala Ser Ala Leu Ala 1235 1240 1245 Ser Val Ser Asn Ile Asn Gly Asn Ser Ala Ser Ala Val His Asn Tyr 1250 1255 1260 Ser Val Asp Ser Ser Ala Pro Thr Ile Ile Ile Asn Thr Val Ala Ser 1265 1270 1275 1280 Asp Asn Ile Val Asn Ala Ser Glu Ala Asp Ala Gly Val Thr Val Ser 1285 1290 1295 Gly Ser Thr Thr Ala Glu Ala Gly Gln Ile Val Thr Ile Thr Leu Asn 1300 1305 1310 Ser Pro Thr Val Gln Thr Tyr Gln Ala Thr Val Gln Ala Asp Gly Ser 1315 1320 1325 Trp Ser Ile Asn Ile Pro Ala Ala Asp Leu Glu Ala Leu Thr Asp Gly 1330 1335 1340 Ser His Thr Leu Thr Ala Thr Val Asn Asp Lys Ala Gly Asn Pro Ala 1345 1350 1355 1360 Ser Thr Thr His Asn Leu Ala Val Asp Leu Thr Val Pro Val Leu Thr 1365 1370 1375 Ile Asn Thr Ile Ala Gly Asp Asp Ile Ile Asn Ala Thr Glu His Gly 1380 1385 1390 Gln Ala Leu Val Ile Ser Gly Ser Ser Thr Gly Gly Glu Ala Gly Asp 1395 1400 1405 Val Val Thr Val Thr Leu Asn Ser Lys Thr Tyr Thr Thr Thr Leu Asp 1410 1415 1420 Ala Ser Gly Asn Trp Ser Val Gly Val Pro Ala Ala Asp Val Thr Ala 1425 1430 1435 1440 Leu Gly Ser Gly Pro Gln Thr Val Thr Ala Thr Val Thr Asp Ala Ala 1445 1450 1455 Gly Asn Ser Asp Asn * 1460 <210> 1058 <211> 5292 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6359..22234) <400> 1058 Val Pro Ala Ser Ala Val Gly Ala Leu Gly Glu Ala Ser Tyr Thr Val 1 5 10 15 Thr Ala Asn Val Thr Asp Ser Ala Gly Asn Ser Asn Ser Ala Ser His 20 25 30 Asn Val Gln Val Asn Thr Ala Leu Pro Gly Val Thr Ile Asn Pro Val 35 40 45 Ala Thr Asp Asp Ile Ile Asn Ala Ala Glu Ser Gly Asn Ala Gln Thr 50 55 60 Ile Ser Gly Gln Val Thr Gly Ala Ala Ala Gly Asp Thr Val Thr Val 65 70 75 80 Thr Leu Gly Gly Lys Thr Tyr Thr Ala Thr Val Gln Gly Asn Leu Ser 85 90 95 Trp Ser Val Asp Val Pro Ala Ala Asp Ile Gln Ala Ile Gly Asn Gly 100 105 110 Asn Leu Thr Val Asn Ala Ser Val Thr Asn Gly Val Gly Asn Thr Gly 115 120 125 Ser Gly Ser Arg Asp Ile Thr Ile Asp Ala Asn Leu Pro Gly Leu Arg 130 135 140 Val Asp Thr Val Ala Gly Asp Asp Val Val Asn Ser Ile Glu His Ala 145 150 155 160 Gln Ala Leu Val Ile Thr Gly Ser Ser Ser Gly Leu Ala Ala Gly Ala 165 170 175 Ala Leu Thr Val Val Ile Asn Thr Val Thr Tyr Ala Ala Thr Val Leu 180 185 190 Ala Asp Gly Thr Trp Ser Val Gly Val Pro Ala Ala Asp Val Ser Asn 195 200 205 Trp Pro Ala Gly Thr Val Asn Ile Thr Val Ser Gly Thr Asn Thr Ala 210 215 220 Gly Thr Thr Ser Thr Ile Thr His Pro Val Thr Val Asp Leu Ala Ala 225 230 235 240 Val Ala Ile Ser Ile Asn Thr Val Ser Gly Asp Asp Val Ile Asn Ala 245 250 255 Ala Glu Lys Gly Ala Asp Leu Thr Leu Ser Gly Ser Thr Ser Gly Val 260 265 270 Glu Val Gly Gln Thr Val Thr Val Thr Phe Gly Gly Lys Thr Tyr Thr 275 280 285 Ala Thr Val Ala Gly Asp Gly Ser Trp Thr Thr Thr Val Pro Ala Ala 290 295 300 Asp Leu Ser Val Leu Arg Asp Gly Asp Ala Thr Val Gln Ala Ser Val 305 310 315 320 Ser Thr Ile Asn Gly Asn Thr Ala Ser Ala Thr His Ala Tyr Ser Val 325 330 335 Asp Ala Thr Ala Pro Thr Leu Ala Ile Asn Thr Ile Ala Thr Asp Asp 340 345 350 Ile Leu Asn Ala Ala Glu Ala Gly Asn Pro Leu Thr Ile Ser Gly Ser 355 360 365 Ser Thr Ala Glu Ala Gly Gln Thr Val Thr Val Thr Leu Asn Gly Val 370 375 380 Thr Tyr Ser Gly Ser Val Gln Ala Asp Gly Ser Trp Ser Val Ser Leu 385 390 395 400 Pro Thr Ala Asp Leu Ser Asn Leu Thr Ala Ser Gln Tyr Thr Val Ser 405 410 415 Ala Ser Val Ser Asp Lys Ala Gly Asn Pro Ala Ser Ala Asn His Gly 420 425 430 Leu Ala Val Asp Leu Thr Val Pro Val Leu Thr Ile Asn Thr Val Ser 435 440 445 Gly Asp Asp Ile Ile Asn Ala Ala Glu His Gly Gln Ala Leu Val Ile 450 455 460 Ser Gly Ser Ser Thr Gly Gly Glu Ala Gly Asp Val Ile Thr Val Thr 465 470 475 480 Leu Asn Ser Lys Thr Tyr Thr Thr Met Leu Asp Ala Ser Gly Asn Trp 485 490 495 Ser Val Gly Val Pro Ala Ala Asp Val Thr Ala Leu Gly Ser Gly Pro 500 505 510 Gln Thr Ile Thr Ala Ala Ile Thr Asp Ala Ala Gly Asn Ser Asp Asp 515 520 525 Ala Ser Arg Thr Val Thr Val Asn Leu Ala Ala Pro Thr Ile Gly Ile 530 535 540 Asn Thr Ile Ala Thr Asp Asp Val Ile Lys Ala Thr Glu Lys Gly Ala 545 550 555 560 Asp Leu Gln Ile Thr Gly Thr Ser Asn Gln Pro Ala Gly Thr Thr Ile 565 570 575 Thr Val Thr Leu Asn Gly Gln Asn Tyr Thr Ala Thr Thr Asp Ser Asn 580 585 590 Gly Asn Trp Ser Ala Thr Val Pro Ala Ser Ala Val Ser Ala Leu Gly 595 600 605 Glu Ala Asn Tyr Thr Val Thr Ala Asn Val Thr Asp Thr Ala Gly Asn 610 615 620 Ser Asn Ser Ala Ser His Asn Val Leu Val Asn Ser Ala Leu Pro Ala 625 630 635 640 Val Thr Ile Asn Ala Val Ala Thr Asp Asp Ile Ile Asn Ala Ala Glu 645 650 655 Ser Gly Asn Ala Gln Thr Ile Ser Gly Gln Val Thr Gly Ala Ala Gln 660 665 670 Gly Asp Thr Val Thr Val Thr Leu Gly Gly Asn Thr Tyr Thr Ala Thr 675 680 685 Val Gln Ser Asn Leu Ser Trp Ser Val Asp Val Pro Ala Ala Asp Ile 690 695 700 Gln Ala Leu Gly Asn Gly Asp Leu Thr Val Asn Ala Ser Val Thr Asn 705 710 715 720 Gly Val Gly Asn Thr Gly Ser Gly Ser Arg Asp Ile Thr Ile Asp Ala 725 730 735 Asn Leu Pro Gly Leu Arg Val Asp Thr Val Ala Gly Asp Asp Val Ile 740 745 750 Asn Ser Ile Glu His Asn Gln Ala Leu Val Ile Thr Gly Ser Ser Ser 755 760 765 Gly Leu Thr Ala Gly Thr Ala Leu Thr Val Glu Ile Asn Asn Val Thr 770 775 780 Tyr Gly Ala Thr Val Leu Ala Asp Gly Thr Trp Ser Leu Gly Val Pro 785 790 795 800 Ala Val Asp Val Ser Asn Trp Pro Ala Gly Thr Val Asn Ile Thr Val 805 810 815 Ser Gly Thr Asn Ser Ala Gly Thr Thr Ser Thr Ile Thr His Pro Val 820 825 830 Thr Val Asp Leu Ala Gly Val Ala Ile Thr Ile Asn Thr Leu Ser Gly 835 840 845 Asp Asp Val Ile Asn Ala Val Glu Lys Gly Glu Thr Leu Val Val Ser 850 855 860 Gly Ser Thr Ser Gly Val Glu Ala Gly Gln Thr Val Thr Val Thr Phe 865 870 875 880 Gly Gly Lys Asn Tyr Thr Thr Thr Val Glu Ala Asn Gly Ser Trp Thr 885 890 895 Val Asn Val Pro Pro Ala Asp Leu Ala Ala Leu Pro Asp Gly Ala Gly 900 905 910 Asn Val Gln Ala Ser Val Ser Asn Ile Asn Gly Asn Ser Ala Gln Ala 915 920 925 Asp Arg Ala Tyr Ser Val Asp Ala Thr Ala Pro Leu Val Thr Ile Asn 930 935 940 Thr Ile Ala Ser Asp Asp Ile Leu Asn Val Ser Glu Ala Gly Ala Gly 945 950 955 960 Ile Thr Ile Ser Gly Thr Thr Thr Ala Gln Ala Gly Gln Thr Leu Thr 965 970 975 Val Thr Leu Asn Asn Asn Thr Tyr Gln Thr Thr Val Leu Ala Asp Gly 980 985 990 Thr Trp Ser Val Asn Val Pro Ala Ala Asp Leu Ser Gly Leu Thr Ala 995 1000 1005 Ser Ser Tyr Thr Val Thr Ala Thr Val Ser Asp Lys Ala Gly Asn Pro 1010 1015 1020 Ala Ser Ala Asp His Ala Leu Val Val Asp Ile Thr Ala Pro Asp Leu 1025 1030 1035 1040 Thr Ile Asn Thr Val Ala Gly Asp Asp Ile Ile Asn Ala Ile Glu His 1045 1050 1055 Gly Gln Ala Leu Val Val Ser Gly Thr Ser Thr Gly Ala Ala Ala Gly 1060 1065 1070 Asp Val Val Thr Val Thr Leu Asn Gly Lys Asn Tyr Thr Thr Thr Leu 1075 1080 1085 Asp Ala Ser Gly Asn Trp Ser Val Gly Ile Pro Ala Ala Asp Val Thr 1090 1095 1100 Ala Leu Ala Thr Gly Ser Gln Thr Ile Thr Ala Ser Leu Ser Asp Arg 1105 1110 1115 1120 Ala Gly Asn Ser Asp Ser Thr Thr His Asp Val Thr Val Asp Leu Ser 1125 1130 1135 Gly Pro Thr Leu Thr Ile Asn Thr Val Ser Gly Asp Asp Ile Ile Asn 1140 1145 1150 Ala Ala Glu Ile Val Val Ala Gln Thr Ile Ser Gly Gln Val Thr Gly 1155 1160 1165 Thr Ala Val Ala Gly Asn Thr Val Ile Val Thr Ile Gly Gly Asn Gln 1170 1175 1180 Tyr Asn Ala Thr Val Gln Ser Asp Leu Ser Trp Ser Val Ser Val Pro 1185 1190 1195 1200 Ala Asn Val Leu Gln Ala Leu Gly Asn Gly Glu Leu Thr Ile Ser Ala 1205 1210 1215 Ser Leu Thr Asn Ser Ala Asn Asn Thr Gly Thr Ala Thr His Asp Ile 1220 1225 1230 Val Ile Asp Ala Asn Leu Pro Gly Leu Arg Val Asp Thr Val Ala Gly 1235 1240 1245 Asp Asp Val Ile Asn Ser Ile Glu His Thr Gln Ala Leu Val Ile Thr 1250 1255 1260 Gly Ser Ser Ser Gly Leu Ala Ala Gly Ala Ala Leu Thr Val Val Ile 1265 1270 1275 1280 Asn Ser Val Thr Tyr Gly Ala Thr Val Leu Ala Asp Gly Ser Trp Ser 1285 1290 1295 Val Gly Val Pro Val Ala Asp Val Thr Asn Trp Pro Ala Gly Thr Val 1300 1305 1310 Asn Ile Ala Val Ser Gly Thr Asn Thr Ala Gly Thr Thr Thr Ser Ile 1315 1320 1325 Ser His Pro Val Thr Val Asp Leu Ala Ala Val Ala Ile Thr Ile Asn 1330 1335 1340 Thr Leu Ser Thr Asp Asp Val Ile Asn Ala Ala Glu Lys Gly Ser Asp 1345 1350 1355 1360 Leu Gln Leu Ser Gly Thr Thr Ser Gly Val Glu Ala Gly Gln Thr Ile 1365 1370 1375 Thr Val Ile Phe Gly Gly Lys Ser Tyr Thr Thr Thr Val Ala Ala Asp 1380 1385 1390 Asn Thr Trp Gly Leu Thr Ile Pro Ala Val Asp Val Ala Thr Leu Pro 1395 1400 1405 Asp Gly Ala Ala Asn Val Gln Ala Ser Val Ser Asn Val Ala Gly Asn 1410 1415 1420 Ser Thr Gln Ala Thr His Ala Tyr Ser Val Asp Ala Thr Ala Pro Ser 1425 1430 1435 1440 Val Thr Ile Asn Thr Ile Ala Thr Asp Asp Ile Leu Asn Ala Ala Glu 1445 1450 1455 Ala Gly Ser Ala Leu Thr Ile Ser Gly Thr Ser Thr Ala Glu Ala Gly 1460 1465 1470 Gln Thr Val Thr Val Thr Leu Asn Gly Val Asn Tyr Ser Gly Asn Val 1475 1480 1485 Gln Ala Asp Gly Ser Trp Ser Val Ser Val Pro Thr Gly Asp Leu Ala 1490 1495 1500 Ser Leu Thr Ala Ser Ser Tyr Thr Val Asn Ala Ser Val Ser Asp Lys 1505 1510 1515 1520 Ala Arg Asn Ser Ala Ser Ala Thr His Asn Leu Thr Val Asp Leu Ala 1525 1530 1535 Ala Pro Val Val Thr Ile Asn Thr Val Ala Gly Asp Asp Ile Ile Asn 1540 1545 1550 Ala Thr Glu His Gly Gln Ala Gln Ile Ile Ser Gly Ser Ala Thr Gly 1555 1560 1565 Ala Thr Thr Gly Asn Thr Val Ser Val Thr Ile Gly Thr Thr Thr Tyr 1570 1575 1580 Thr Thr Val Leu Asp Ala Asn Gly Asn Trp Ser Ile Gly Val Pro Ala 1585 1590 1595 1600 Ser Val Ile Ser Ala Leu Ala Gln Gly Asp Val Thr Ile Thr Ala Thr 1605 1610 1615 Val Thr Asp Ser Ala Gly Asn Ser Gly Thr Ala Ser His Thr Val Thr 1620 1625 1630 Val Ala Leu Gly Ala Pro Val Leu Ala Ile Asn Thr Ile Ala Val Asp 1635 1640 1645 Asp Ile Ile Asn Ala Ala Glu Lys Gly Ala Asp Leu Ala Ile Thr Gly 1650 1655 1660 Thr Ser Asn Gln Pro Ala Gly Thr Gln Ile Thr Val Thr Leu Asn Gly 1665 1670 1675 1680 Gln Asn Tyr Thr Thr Thr Ala Asp Ala Ser Gly Asn Trp Ser Val Thr 1685 1690 1695 Val Pro Ala Ser Arg Val Ser Ala Leu Gly Glu Ala Thr Tyr Thr Val 1700 1705 1710 Thr Ala Ala Ala Thr Asp Ala Asp Gly Asn Ser Gly Ser Ala Ser His 1715 1720 1725 Asn Val Gln Val Asn Thr Ala Leu Pro Gly Val Thr Ile Asn Val Val 1730 1735 1740 Ala Thr Asp Asp Ile Ile Asn Ala Ala Glu Ala Gly Val Glu Gln Thr 1745 1750 1755 1760 Ile Ser Gly Gln Val Thr Gly Ala Ala Ala Gly Asp Thr Val Thr Val 1765 1770 1775 Thr Leu Gly Gly Ala Thr Tyr Thr Ala Thr Val Gln Ala Asn Leu Ser 1780 1785 1790 Trp Ser Val Asp Val Pro Ala Ser Ala Leu Gln Glu Leu Gly Asn Gly 1795 1800 1805 Glu Leu Thr Ile Ser Ala Ser Val Thr Asn Ser Val Gly Asn Thr Gly 1810 1815 1820 Asn Gly Thr Arg Glu Ile Thr Ile Asp Ala Asn Leu Pro Gly Leu Arg 1825 1830 1835 1840 Val Asp Thr Val Ala Gly Asp Asp Val Val Asn Ile Ile Glu His Gly 1845 1850 1855 Gln Ala Leu Val Ile Thr Gly Ser Ser Ser Gly Leu Ala Ala Gly Ser 1860 1865 1870 Asn Val Thr Leu Thr Ile Asn Gly Gln Thr Tyr Val Ala Ala Val Leu 1875 1880 1885 Ala Asp Gly Thr Trp Ser Val Gly Val Pro Ala Val Asp Val Ser Ala 1890 1895 1900 Trp Pro Ala Gly Ser Val Thr Ile Ala Ala Ser Gly Ser Thr Ser Ala 1905 1910 1915 1920 Gly Asn Pro Val Ser Val Thr His Pro Val Thr Val Asp Leu Ser Ala 1925 1930 1935 Val Ala Val Ser Ile Asn Ala Ile Thr Ala Asp Asp Val Ile Asn Ala 1940 1945 1950 Ala Glu Lys Gly Ala Ala Leu Thr Leu Ser Gly Ser Thr Ser Gly Val 1955 1960 1965 Glu Ala Gly Gln Thr Val Thr Val Thr Phe Gly Gly Lys Thr Tyr Ser 1970 1975 1980 Ala Thr Val Ala Ala Asn Gly Ser Trp Ser Thr Ser Val Pro Ala Ala 1985 1990 1995 2000 Asp Met Ala Ala Leu Arg Asp Gly Asp Ala Ser Ala Gln Ala Ser Val 2005 2010 2015 Ser Asn Val Asn Gly Asn Ser Ala Thr Thr Thr His Ala Tyr Ser Val 2020 2025 2030 Asp Ala Ser Ala Pro Thr Val Thr Ile Asn Thr Ile Ala Gly Asp Asp 2035 2040 2045 Ile Leu Asn Ala Ala Glu Ala Gly Ala Ala Leu Thr Ile Thr Gly Ser 2050 2055 2060 Ser Thr Ala Glu Ala Gly Gln Thr Val Thr Val Thr Leu Asn Gly Thr 2065 2070 2075 2080 Asn Tyr Thr Gly Thr Val Gln Thr Asp Gly Ser Trp Ser Val Ser Val 2085 2090 2095 Pro Ser Ala Asp Leu Ser Thr Leu Thr Ala Ser Asn Tyr Thr Val Asn 2100 2105 2110 Ala Ala Val Ser Asp Lys Ala Gly Asn Pro Ala Ser Val Asn His Asn 2115 2120 2125 Leu Thr Val Asp Thr Ser Val Pro Val Val Thr Ile Asn Thr Val Ala 2130 2135 2140 Gly Asp Asp Val Ile Asn Ala Thr Glu His Ala Gln Ala Gln Ile Ile 2145 2150 2155 2160 Ser Gly Ser Ala Thr Gly Ala Ala Thr Gly Ser Thr Val Thr Val Thr 2165 2170 2175 Ile Gly Thr Asn Thr Phe Thr Thr Val Leu Asp Ala Ser Gly Asn Trp 2180 2185 2190 Ser Val Gly Val Pro Ala Ser Val Val Ser Ala Leu Ala Asn Gly Thr 2195 2200 2205 Val Thr Ile Asn Ala Ser Val Thr Asp Ala Gly Gly Asn Ser Gly Ser 2210 2215 2220 Ala Thr His Gln Val Thr Val Asn Thr Gly Leu Pro Thr Ile Thr Phe 2225 2230 2235 2240 Asn Ala Ile Ser Gly Asp Asn Ile Leu Asn Ala Asp Glu Lys Gly Gln 2245 2250 2255 Pro Leu Thr Ile Ser Gly Gly Ser Thr Gly Leu Ala Thr Gly Ala Gln 2260 2265 2270 Val Thr Val Thr Leu Asn Gly His Asn Tyr Ser Ala Thr Thr Asp Ala 2275 2280 2285 Ser Gly Asn Trp Thr Leu Thr Val Pro Val Ser Asp Leu Ala Ala Leu 2290 2295 2300 Gly Gln Ala Asn Tyr Thr Val Ser Ala Ser Ala Thr Ser Ala Ala Gly 2305 2310 2315 2320 Asn Thr Ala Ser Ser Gln Ala Asn Leu Leu Val Asp Ser Gly Leu Pro 2325 2330 2335 Asp Val Thr Ile Asn Thr Val Ala Gly Asp Asp Ile Ile Asn Ala Ala 2340 2345 2350 Glu Ala Gly Ala Asp Gln Thr Ile Ser Gly Val Val Thr Arg Ala Ala 2355 2360 2365 Ala Gly Asp Thr Val Thr Val Thr Leu Gly Gly Asn Thr Tyr Thr Ala 2370 2375 2380 Thr Val Gln Ser Asn Leu Ser Trp Ser Val Ser Val Pro Thr Ala Asp 2385 2390 2395 2400 Leu Gln Ala Leu Gly Asn Gly Asp Leu Thr Ile Thr Ala Ser Val Thr 2405 2410 2415 Asn Ala Asn Gly Asn Thr Gly Ser Gly Thr Arg Asp Ile Thr Ile Asp 2420 2425 2430 Ala Asn Leu Pro Gly Leu Arg Val Asp Thr Val Ala Gly Asp Asp Ile 2435 2440 2445 Val Asn Ser Ile Glu His Gly Gln Ala Leu Val Ile Thr Gly Gly Ser 2450 2455 2460 Ser Gly Leu Asn Ala Gly Ala Val Leu Thr Val Thr Ile Asn Ser Val 2465 2470 2475 2480 Ala Tyr Ser Ala Thr Val Gln Ala Asp Gly Ser Trp Ser Val Gly Ile 2485 2490 2495 Pro Ala Ala Asn Val Ser Ala Trp Pro Ala Gly Pro Leu Thr Val Glu 2500 2505 2510 Val Asp Gly Gln Ser Ser Ala Asn Asn Pro Val Ser Val Ser His Pro 2515 2520 2525 Phe Thr Val Asp Leu Thr Ala Val Ala Ile Ser Ile Asn Thr Val Ala 2530 2535 2540 Ser Asp Asp Val Ile Asn Ala Ala Glu Lys Gly Thr Asn Leu Thr Leu 2545 2550 2555 2560 Ser Gly Ser Thr Ser Gly Ile Glu Ser Gly Gln Thr Val Thr Val Thr 2565 2570 2575 Phe Gly Gly Lys Thr Tyr Thr Ala Ser Val Ala Ala Asn Gly Ser Trp 2580 2585 2590 Ser Val Asn Val Pro Ala Ala Asp Leu Ala Thr Leu Pro Glu Gly Ala 2595 2600 2605 Ala Asn Val Gln Ala Ser Val Ser Ser Ala Ser Gly Asn Ser Ala Ser 2610 2615 2620 Ala Thr His Ala Tyr Ser Val Asp Ala Ser Ala Pro Thr Leu Thr Ile 2625 2630 2635 2640 Asn Thr Ile Ala Ser Asp Asp Ile Leu Asn Ala Ala Glu Ala Gly Ser 2645 2650 2655 Pro Leu Thr Ile Ser Gly Thr Ser Thr Ala Glu Thr Gly Gln Thr Val 2660 2665 2670 Thr Val Thr Leu Asn Gly Ala Thr Tyr Thr Gly Thr Val Gln Ala Asp 2675 2680 2685 Gly Ser Trp Ser Val Ser Val Pro Thr Ser Ala Leu Gly Ala Leu Asn 2690 2695 2700 Ala Ser Asn Tyr Thr Val Ser Ala Thr Val Asn Asp Lys Ala Gly Asn 2705 2710 2715 2720 Pro Gly Ser Ala Ser His Asn Leu Ala Val Asp Thr Thr Ala Pro Val 2725 2730 2735 Leu Thr Ile Asn Thr Val Ala Gly Asp Asp Ile Ile Asn Asp Ala Glu 2740 2745 2750 His Ala Gln Ala Leu Val Ile Ser Gly Thr Ser Ser Gly Gly Glu Ala 2755 2760 2765 Gly Asp Val Val Ser Val Val Leu Asn Gly Lys Thr Tyr Thr Thr Thr 2770 2775 2780 Leu Asp Ala Ser Gly Asn Trp Ser Val Gly Val Pro Ala Ala Asp Val 2785 2790 2795 2800 Thr Ala Leu Gly Ser Gly Ala Gln Thr Ile Thr Ala Ser Val Ser Asp 2805 2810 2815 Arg Ala Gly Asn Ser Asp Asp Ala Ser Arg Thr Val Thr Val Ser Leu 2820 2825 2830 Ser Ala Pro Val Ile Ser Ile Asn Thr Ile Ala Gly Asp Asp Val Ile 2835 2840 2845 Asn Ala Thr Glu Lys Gly Ser Asp Leu Ala Leu Ser Gly Thr Ser Asp 2850 2855 2860 Gln Pro Ala Gly Thr Ala Ile Thr Val Thr Leu Asn Gly Gln Asn Tyr 2865 2870 2875 2880 Ser Ala Thr Thr Asp Ala Ser Gly Asn Trp Ser Val Thr Val Pro Ala 2885 2890 2895 Ser Ala Val Ser Ala Leu Gly Glu Ala Thr Tyr Ser Val Thr Ala Ser 2900 2905 2910 Val Thr Asn Ala Gln Gly Asn Ser Ser Thr Ala Ser His Asn Val Gln 2915 2920 2925 Val Asn Thr Ala Leu Pro Gly Ile Thr Ile Asn Pro Val Ala Thr Asp 2930 2935 2940 Asp Ile Ile Asn Ala Ser Glu Ala Gly Ser Ala Gln Thr Ile Ser Gly 2945 2950 2955 2960 Gln Val Thr Gly Ala Ala Ala Gly Ser Thr Val Thr Val Glu Leu Gly 2965 2970 2975 Gly Lys Thr Tyr Thr Ala Thr Val Gln Ala Asp Leu Ser Trp Asn Val 2980 2985 2990 Ser Val Pro Ala Ala Asp Trp Gln Ala Leu Gly Asn Gly Glu Leu Thr 2995 3000 3005 Val Asn Ala Ser Val Thr Asn Ala Val Gly Asn Thr Gly Ser Gly Thr 3010 3015 3020 Arg Asp Ile Thr Ile Asp Ala Ser Leu Pro Gly Leu Arg Val Asp Thr 3025 3030 3035 3040 Val Ala Gly Asp Asp Val Val Asn Ile Ile Glu His Ala Gln Ala Gln 3045 3050 3055 Val Ile Thr Gly Ser Ser Ser Gly Phe Ala Ala Gly Thr Ala Leu Thr 3060 3065 3070 Val Val Ile Asn Asn Gln Thr Tyr Ala Ala Thr Val Leu Ala Asn Gly 3075 3080 3085 Ser Trp Ser Val Gly Val Pro Ala Thr Asp Val Ser Asn Trp Pro Ala 3090 3095 3100 Gly Thr Leu Asn Ile Thr Val Ser Gly Ala Asn Ser Ala Gly Thr Gln 3105 3110 3115 3120 Thr Ser Ile Thr His Pro Leu Thr Val Asp Leu Thr Ala Val Ala Ile 3125 3130 3135 Ser Met Asn Ser Ile Thr Ser Asp Asp Ala Ile Asn Ala Ala Glu Lys 3140 3145 3150 Gly Ala Ala Leu Thr Leu Ser Gly Ser Thr Ser Gly Val Glu Ala Gly 3155 3160 3165 Gln Thr Val Thr Val Thr Phe Gly Gly Lys Thr Tyr Thr Thr Thr Val 3170 3175 3180 Ala Ala Asn Gly Ser Trp Ser Thr Thr Val Pro Ala Ala Asp Leu Ala 3185 3190 3195 3200 Ala Leu Arg Asp Gly Asp Ala Ser Ala Gln Val Arg Val Thr Asn Val 3205 3210 3215 Asn Gly Asn Ser Ala Thr Ala Thr His Glu Tyr Ser Val Asp Ser Ala 3220 3225 3230 Ala Pro Thr Val Thr Ile Asn Thr Ile Ala Ser Asp Asn Ile Ile Asn 3235 3240 3245 Ala Ser Glu Ala Ala Ala Gly Val Thr Val Ser Gly Thr Ser Thr Ala 3250 3255 3260 Gln Thr Gly Gln Thr Leu Thr Val Thr Leu Asn Gly Thr Asn Tyr Gln 3265 3270 3275 3280 Thr Thr Val Gln Thr Asp Gly Ser Trp Ser Leu Thr Leu Pro Ala Ser 3285 3290 3295 Asp Leu Thr Ala Leu Ala Asn Asn Gly Tyr Thr Leu Thr Ala Thr Val 3300 3305 3310 Ser Asp Leu Ala Gly Asn Leu Gly Ser Ala Ser Lys Gly Val Thr Val 3315 3320 3325 Asp Thr Thr Ala Pro Val Ile Ser Phe Asn Thr Val Ala Gly Asp Asp 3330 3335 3340 Val Ile Asn Asn Val Glu His Ile Gln Ala Gln Ile Ile Ser Gly Thr 3345 3350 3355 3360 Ala Thr Gly Ala Val Ala Gly Asp Arg Leu Val Val Thr Ile Ala Gly 3365 3370 3375 Gln Gln Tyr Val Thr Ser Thr Asp Ala Ser Gly Asn Trp Ser Val Gly 3380 3385 3390 Val Pro Ala Ser Val Ile Ser Gly Leu Ala Asp Gly Thr Val Thr Ile 3395 3400 3405 Ser Ala Thr Ile Thr Asp Ser Ala Gly Asn Ser Ser Thr Gln Thr His 3410 3415 3420 Asn Val Gln Val Asn Thr Ala Ala Val Ser Leu Ser Val Ser Thr Ile 3425 3430 3435 3440 Ser Gly Asp Asn Leu Ile Asn Ala Ala Glu Ala Gly Ser Ala Leu Thr 3445 3450 3455 Leu Ser Gly Thr Gly Thr Asn Phe Ala Thr Gly Thr Val Val Thr Val 3460 3465 3470 Leu Leu Asn Gly Lys Gly Tyr Ser Ala Thr Ile Gln Ser Asn Gly Ser 3475 3480 3485 Trp Ser Val Asn Val Pro Ala Ala Asp Val Ala Ala Leu Ser Asp Gly 3490 3495 3500 Thr Ser Tyr Thr Val Ser Ala Ser Ala Gln Asp Ser Ala Gly Asn Gly 3505 3510 3515 3520 Asn Ser Ser Thr Gln Thr His Asn Val Gln Val Asn Thr Ala Ala Val 3525 3530 3535 Ser Leu Ser Val Ser Thr Ile Ser Gly Asp Asn Leu Ile Asn Ala Ala 3540 3545 3550 Glu Ala Gly Ser Ala Leu Thr Leu Ser Gly Thr Gly Thr Asn Phe Ala 3555 3560 3565 Thr Gly Thr Val Val Thr Val Leu Leu Asn Gly Lys Gly Tyr Ser Ala 3570 3575 3580 Thr Ile Gln Ser Asn Gly Ser Trp Ser Val Asn Val Pro Ala Ala Asp 3585 3590 3595 3600 Val Ala Ala Leu Ser Asp Gly Thr Ser Tyr Thr Val Ser Ala Ser Ala 3605 3610 3615 Gln Asp Ser Ala Gly Asn Ser Ala Thr Ala Ser Arg Ser Val Ala Val 3620 3625 3630 Asp Leu Thr Ala Pro Val Ile Ser Ile Asn Thr Val Ser Thr Asp Asp 3635 3640 3645 Arg Leu Asn Ala Ala Glu Gln Gln Gln Pro Leu Thr Leu Asn Gly Ser 3650 3655 3660 Thr Ser Ala Glu Val Gly Gln Thr Val Thr Val Thr Phe Gly Gly Lys 3665 3670 3675 3680 Thr Tyr Thr Ala Thr Val Ala Ala Asn Gly Thr Trp Ala Leu Asn Val 3685 3690 3695 Pro Ala Val Asp Leu Ala Ala Leu Gly Gln Gly Ala Gln Thr Ile Thr 3700 3705 3710 Ala Ser Val Asn Asp Arg Ala Gly Asn Pro Gly Gln Ala Thr His Ala 3715 3720 3725 Leu Thr Val Asp Thr Val Ala Pro Thr Val Thr Ile Ala Thr Val Ala 3730 3735 3740 Gly Asp Asp Ile Ile Asn Asn Ala Glu Gln Leu Ala Gly Gln Thr Ile 3745 3750 3755 3760 Ser Gly Thr Thr Thr Ala Glu Val Gly Gln Thr Val Thr Val Thr Phe 3765 3770 3775 Asn Gly Gln Thr Trp Ser Ala Thr Val Gly Ser Gly Gly Ser Trp Ser 3780 3785 3790 Val Phe Ile Pro Ala Gln Gln Phe Ala Gly Leu Ser Asp Gly Ser Tyr 3795 3800 3805 Thr Ile Ser Ala Thr Val Ser Asp Gln Ala Gly Asn Pro Gly Ser Ala 3810 3815 3820 Ser Arg Gly Val Thr Leu Asn Gly Asp Val Pro Thr Val Thr Ile Asn 3825 3830 3835 3840 Thr Phe Ala Gly Asp Asp Val Val Asn Ala Ala Glu His Gly Ser Ser 3845 3850 3855 Leu Val Ile Ser Gly Thr Thr Thr Ala Pro Val Gly Gln Thr Leu Thr 3860 3865 3870 Leu Thr Leu Asn Gly Lys Thr Tyr Thr Thr Thr Val Gln Thr Gly Gly 3875 3880 3885 Ser Trp Ser Tyr Thr Leu Gly Ser Ala Asp Val Thr Ala Leu Ala Asp 3890 3895 3900 Gly Asn Ala Tyr Val Ile Asn Ala Ser Val Ser Asn Ala Ile Gly Asn 3905 3910 3915 3920 Thr Gly Ser Ser Asn His Thr Ile Thr Val Asp Leu Ser Ala Pro Ala 3925 3930 3935 Met Gly Ile Asn Ile Asp Ser Leu Gln Ala Asp Thr Gly Leu Ser Ala 3940 3945 3950 Ser Asp Phe Ile Thr Ser Val Ser Pro Val Val Val Asn Gly Ser Leu 3955 3960 3965 Thr Ala Ala Leu Ala Ser Asn Glu Thr Ala Gln Ile Ser Ile Asp Gly 3970 3975 3980 Gly Thr Thr Trp Thr Thr Leu Thr Val Thr Gly Thr Thr Trp Arg Tyr 3985 3990 3995 4000 Asn Asp Ser Arg Thr Leu Thr Asp Gly Asn Tyr Leu Tyr Gln Val Arg 4005 4010 4015 Val Ile Asp Ala Ala Gly Asn Val Gly Ala Thr Asp Ser Gln Asn Val 4020 4025 4030 Val Ile Asp Thr Thr Ala Pro Asp Pro Ala Val Lys Thr Ile Ala Ile 4035 4040 4045 Ser Ala Ile Thr Thr Asp Met Gly Leu Ile Thr Asn Asp Phe Val Thr 4050 4055 4060 Ser Asp Thr Thr Leu Ala Val Ser Gly Thr Leu Gly Ala Thr Leu Ser 4065 4070 4075 4080 Ala Gly Glu Phe Ala Gln Ile Ser Leu Asp Gly Gly Val Thr Trp Thr 4085 4090 4095 Thr Leu Thr Val Val Gly Thr Ser Trp Ser Tyr Ala Asp Gly His Thr 4100 4105 4110 Leu Thr Asp Gly Thr Trp Asn Tyr Thr Val Arg Val Val Asp Leu Ala 4115 4120 4125 Gly Asn Val Gly Gln Thr Ala Thr Gln Asn Val Val Val Asp Thr Thr 4130 4135 4140 Ser Pro Glu Ala Ala Lys Ser Ile Thr Ile Thr Gly Ile Ser Asp Asp 4145 4150 4155 4160 Thr Gly Thr Ser Ser Ser Asp Phe Ile Thr Ser Asp Thr Thr Leu Thr 4165 4170 4175 Val Arg Gly Val Leu Gly Ala Ala Leu Gly Ala Asn Glu Phe Ala Gln 4180 4185 4190 Ile Ser Thr Asp Asn Gly Ala Thr Trp Val Asn Val Thr Val Ala Ala 4195 4200 4205 Asp Ser Leu Asn Trp Ser Tyr Val Asp Gly Arg Thr Leu Thr Asn Gly 4210 4215 4220 Thr Thr Thr Trp Gln Val Arg Val Val Asp Leu Ala Gly Asn Val Gly 4225 4230 4235 4240 Ala Thr Ser Ser Gln Ser Ala Leu Ile Asp Thr Val Asn Pro Ala Gln 4245 4250 4255 Val Leu Thr Ile Ala Ser Ile Ser Thr Asp Thr Gly Ser Ser Ala Thr 4260 4265 4270 Asp Phe Ile Thr Ser Asp Thr Met Leu Thr Leu Thr Gly Ser Leu Gly 4275 4280 4285 Ala Gly Leu Ala Ser Gly Glu Val Ala Gln Ile Ser Leu Asp Ser Gly 4290 4295 4300 Ala Thr Trp Thr Thr Leu Thr Thr Asn Gly Thr Gln Trp Thr Tyr Thr 4305 4310 4315 4320 Asp Ser Arg Thr Leu Thr Asp Gly Ser Tyr Val Tyr Gln Val Arg Val 4325 4330 4335 Leu Asp Leu Ala Gly Asn Thr Gly Pro Val Val Ser Lys Thr Val Val 4340 4345 4350 Val Asp Thr Ile Asn Pro Thr Ala Thr Pro Thr Ile Val Ser Tyr Thr 4355 4360 4365 Asp Asp Val Gly Gln Arg Gln Gly Thr Leu Ser Ser Ser Gln Ala Thr 4370 4375 4380 Asp Asp Thr Thr Pro Leu Leu Asn Gly Val Leu Ser Ala Pro Leu Ala 4385 4390 4395 4400 Ser Gly Glu Val Val Tyr Leu Tyr Arg Asn Gly Leu Leu Leu Gly Ala 4405 4410 4415 Val Thr Met Val Gly Ala Leu Asn Trp Thr Tyr Ser Asp Ser Gly Leu 4420 4425 4430 Val Ser Gly Ala Tyr Thr Tyr Ser Ala Arg Val Val Asp Leu Ala Gly 4435 4440 4445 Asn Ile Thr Ser Ser Ser Asp Phe Val Leu Thr Val Asp Thr Ser Ile 4450 4455 4460 Pro Thr Thr Leu Ala Gln Ile Thr Ser Gln Thr Thr Arg Asp Thr Thr 4465 4470 4475 4480 Pro Ile Ile Ser Gly Val Ile Thr Ala Ala Leu Ala Ser Gly Gln Tyr 4485 4490 4495 Val Glu Val Val Ile Asn Gly Lys Thr Tyr Thr Ser Glu Pro Gly Gly 4500 4505 4510 Ala Val Val Val Asp Pro Ala His Asn Thr Trp Tyr Val Gln Leu Pro 4515 4520 4525 Asp Thr Asp Ala Leu Thr Val Ser Ala Thr Ala Tyr Thr Val Thr Ala 4530 4535 4540 Gln Val Lys Ser Ser Ala Gly Asn Gly Asn Asn Ala Asn Ile Ser Asn 4545 4550 4555 4560 Gly Thr Val Thr Val Asn Ala Ala Ile Asp Tyr Thr Pro Thr Trp Thr 4565 4570 4575 Thr Ala Ser Lys Thr Thr Ala Trp Gly Leu Thr Tyr Gly Leu Asp Ser 4580 4585 4590 His Gly Met Trp Thr Val Leu Ala Asn Gln Gln Val Met Gln Ser Thr 4595 4600 4605 Asp Pro Leu Thr Trp Ser Lys Thr Ala Leu Thr Leu Tyr Gln Ser Gly 4610 4615 4620 Asn Asn Tyr Ala Thr Ser Ser Ile Ala Asp Tyr Asp Arg Asn Gly Thr 4625 4630 4635 4640 Gly Asp Leu Phe Ile Thr Arg Asp Asp Tyr Gly Thr Gly Tyr Ile Asn 4645 4650 4655 Gly Phe Thr Asn Asn Gly Asp Gly Thr Phe Ser Ser Ala Ile Gln Val 4660 4665 4670 Thr Val Gly Thr Leu Thr Trp Tyr Gly Ser Ile Val Ala Phe Asp Lys 4675 4680 4685 Glu Gly Asp Gly Tyr Leu Asp Phe Trp Ile Gly Asp Ala Gly Gly Pro 4690 4695 4700 Asp Ser Asn Thr Phe Leu Trp Asn Asn Ala Gly Thr Leu Val Gly Asn 4705 4710 4715 4720 Ser Thr Thr Ser Asn Ser Gly Gly Ser Ala Thr Val Gly Gly Ala Val 4725 4730 4735 Thr Gly Tyr Leu Ser Leu Asn Glu Gly Ser Gly Val Asp Leu Asn Asn 4740 4745 4750 Asp Gly Arg Ile Asp Leu Val Gln His Thr Tyr Asn Leu Asn Asn Tyr 4755 4760 4765 Tyr Thr Leu Ser Ser Leu Ile Asn Gln Gly Asn Gly Thr Phe Val Trp 4770 4775 4780 Gly Gln Asn Thr Thr Asn Thr Phe Leu Ser Gly Ala Gly Ser Gly Ala 4785 4790 4795 4800 Met Ser Ser Ser Val Ser Met Thr Trp Ala Asp Phe Asp Gly Asp Gly 4805 4810 4815 Asp Met Asp Leu Phe Leu Pro Ala Ser Gln Gly Arg Ala Asn Tyr Gly 4820 4825 4830 Ser Leu Leu Phe Asn Thr Asn Gly Val Leu Gly Cys Pro Val Ala Val 4835 4840 4845 Gly Ala Thr Ala Thr Thr Tyr Ala Ser Gln Phe Ser Leu Ala Val Asp 4850 4855 4860 Trp Asn His Asp Gly Leu Met Asp Ile Ala Arg Ile Ala Gln Thr Gly 4865 4870 4875 4880 Gln Ser Tyr Leu Tyr Thr Asn Val Ser Asn Ala Ser Asn Trp Thr Gln 4885 4890 4895 Ser Ala Leu Gly Gly Ser Gln Ser Gly Thr Thr Ser Gly Val Ala Ala 4900 4905 4910 Met Asp Tyr Asp Trp Asp Gly Ala Val Asp Val Leu Val Ser Lys Gln 4915 4920 4925 Ser Gly Ser Val Phe Leu Ser Arg Asn Thr Asn Thr Val Ser Tyr Gly 4930 4935 4940 Thr Ser Leu His Leu Arg Ile Thr Asp Pro Asn Gly Ile Asn Val Tyr 4945 4950 4955 4960 Tyr Gly Asn Thr Val Lys Leu Tyr Asn Ser Ala Gly Val Leu Val Ala 4965 4970 4975 Thr Gln Ile Ile Asn Pro Gln Ser Gly Met Gly Val Asn Asp Thr Ser 4980 4985 4990 Ala Leu Val Asn Phe Tyr Gly Leu Asn Ala Gly Glu Thr Tyr Asn Ala 4995 5000 5005 Val Leu Ile Lys Ser Thr Gly Thr Thr Ala Ser Asn Ile Asp Gln Thr 5010 5015 5020 Val Asn Thr Ser Trp Gly Gly Leu Gln Ala Thr Asp Ala Thr His Ala 5025 5030 5035 5040 Tyr Asp Leu Ser Ala Glu Ala Gly Thr Ala Ser Asn Asn Gly Lys Phe 5045 5050 5055 Val Gly Thr Gly Tyr Asn Asp Thr Phe Phe Ala Thr Ala Gly Thr Asp 5060 5065 5070 Thr Tyr Asp Gly Ser Gly Gly Trp Val Tyr Ser Ser Gly Thr Gly Thr 5075 5080 5085 Trp Leu Ala Asn Gly Gly Met Asp Val Val Asp Phe Arg Leu Ser Thr 5090 5095 5100 Val Gly Val Thr Ala Asn Leu Ser Ser Thr Ala Ala Gln Ala Thr Gly 5105 5110 5115 5120 Phe Asn Thr Ser Thr Phe Thr Asn Ile Glu Gly Ile Ser Gly Ser Asn 5125 5130 5135 Phe Asn Asp Ile Leu Thr Gly Ser Ser Gly Asp Asn Gln Leu Glu Gly 5140 5145 5150 Arg Gly Gly Asn Asp Thr Leu Asn Ile Gly Asn Gly Gly His Asp Thr 5155 5160 5165 Leu Leu Tyr Lys Leu Leu Asn Ala Ser Asp Ala Thr Gly Gly Asn Gly 5170 5175 5180 Ser Asp Val Val Asn Gly Phe Thr Val Gly Thr Trp Glu Gly Thr Ala 5185 5190 5195 5200 Asp Thr Asp Arg Ile Asp Ile Arg Glu Leu Leu Gln Gly Ser Gly Tyr 5205 5210 5215 Thr Gly Asn Gly Lys Ala Ser Tyr Val Asn Gly Val Ala Thr Leu Asp 5220 5225 5230 Ala Gln Ala Gly Asn Ile Gly Asp Phe Val Lys Val Thr Gln Ser Gly 5235 5240 5245 Ser Asp Thr Ile Val Gln Ile Asp Arg Asp Gly Thr Gly Gly Thr Phe 5250 5255 5260 Ala Thr Thr Asn Val Val Thr Leu Thr Gly Val His Thr Asp Leu Ala 5265 5270 5275 5280 Thr Leu Leu Ala Asn His Gln Leu Met Val Val * 5285 5290 <210> 1059 <211> 707 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22280..24400) <400> 1059 Met Ile Ala Val Ala Arg Tyr Tyr Arg Leu Asp Phe Ser Gln Glu Asn 1 5 10 15 Val Arg Ala Thr Val Asn Trp Glu Arg Asp Ser Lys Arg Glu Glu Leu 20 25 30 Leu Thr Asp Met Ala Arg Gln Leu Gly Met Gly Leu Arg Leu Val Glu 35 40 45 Phe Ser Ala Asp Ser Leu Asn Pro Trp Arg Leu Pro Leu Ile Ala Val 50 55 60 Phe Asp Asn Gln Gln Ile Gly Val Ile Thr Arg Arg Asp Asn His Asp 65 70 75 80 Asn Ile Ser Val Gln Phe Ser Gly Asp Glu Gly Leu Glu Thr Thr Leu 85 90 95 Asn Val Ala Asp Ile Glu Asp Lys Ile Val Glu Leu Ala Leu Leu Arg 100 105 110 Pro Leu Ser Ala Ile Pro Asp Ala Arg Val Asp Asp Tyr Ile Arg Pro 115 120 125 Tyr Gln Ala Asn Trp Phe Trp Ser Leu Ser Leu Lys Asp Trp Arg Arg 130 135 140 Tyr Gly Asp Ile Met Leu Ala Ser Leu Val Ala Asn Val Leu Ala Leu 145 150 155 160 Ala Ala Met Ile Phe Ser Met Gln Val Tyr Asp Arg Val Val Pro Ala 165 170 175 Gln Ser Tyr Pro Thr Leu Trp Val Leu Phe Ala Gly Val Met Met Ala 180 185 190 Ile Leu Phe Glu Phe Cys Met Arg Met Val Arg Thr His Leu Ser Asp 195 200 205 Val Ile Gly Lys Arg Ala Asp Leu Arg Ile Ser Asp Arg Val Phe Gly 210 215 220 His Ala Leu Arg Leu Lys Asn Asn Val Arg Ser Lys Ser Thr Gly Ser 225 230 235 240 Phe Ile Ser Gln Ile Arg Glu Leu Glu Ser Val Arg Glu Leu Ile Thr 245 250 255 Ser Thr Thr Ile Gly Ala Val Ala Asp Leu Pro Phe Phe Leu Leu Phe 260 265 270 Val Phe Ile Leu Trp Met Ile Gly Gly Trp Leu Val Leu Val Val Leu 275 280 285 Leu Ala Leu Pro Leu Leu Val Ile Pro Gly Leu Leu Val Gln Arg Pro 290 295 300 Leu Ala Arg Leu Ala Asn Glu Gly Met Arg Glu Ser Ala Val Arg Asn 305 310 315 320 Ala Thr Leu Val Glu Ala Val Gln Ser Ile Glu Asp Ile Lys Leu Leu 325 330 335 Arg Ala Glu Gln Arg Phe Gln Asn Gln Trp Asn His Thr Asn Asp Val 340 345 350 Ala Ser Ser Ile Ser Met Lys Gln Arg Phe Leu Thr Gly Leu Leu Leu 355 360 365 Thr Trp Thr Gln Glu Val Gln Ser Ile Val Tyr Val Val Val Leu Leu 370 375 380 Val Gly Cys Phe Met Val Met Asn Gly Asp Met Thr Thr Gly Ala Leu 385 390 395 400 Val Gly Thr Thr Ile Leu Ala Ser Arg Thr Ile Ala Pro Leu Ser Gln 405 410 415 Ile Ser Gly Val Leu Ser Arg Trp Gln Gln Ala Lys Val Ala Arg Asn 420 425 430 Gly Leu Asp Glu Leu Met Lys Arg Pro Val Asp Gln Pro Glu His Gly 435 440 445 Lys Leu Val His Lys Ala Val Leu His Gly Asn Tyr Gln Phe Ser Asn 450 455 460 Ala Val Phe Tyr Tyr Asp Glu Glu Glu Lys Ile Ala Asp Val Ala Ile 465 470 475 480 Gly Lys Leu Asn Ile Gln Ala Gly Glu Lys Ile Ala Ile Leu Gly Arg 485 490 495 Asn Gly Ala Gly Lys Ser Thr Leu Leu Gln Met Leu Ala Gly Met Arg 500 505 510 Ile Ala Gln Gln Gly Gln Val Leu Leu Asp Asn Ile Ser Ile Gly Gln 515 520 525 Leu Asp Pro Ala Asp Leu Arg Arg Asp Met Gly Leu Leu Ser Gln Thr 530 535 540 Gly Arg Leu Phe Phe Gly Ser Leu Arg Glu Asn Leu Thr Met Gly Met 545 550 555 560 Pro Glu Ala Ser Asp Glu Asp Ile Glu Arg Ala Leu Thr Leu Ser Gly 565 570 575 Ala Leu Pro Phe Val Gln Lys Gln Lys Asn Gly Leu Asn Tyr Met Ile 580 585 590 Gln Glu Gly Gly Phe Gly Leu Ser Gly Gly Gln Arg Gln Thr Leu Leu 595 600 605 Leu Ala Arg Leu Leu Ile Ser Gln Pro Asn Ile Val Leu Leu Asp Glu 610 615 620 Pro Ser Ala Ser Leu Asp Glu Met Ala Glu Ala Tyr Leu Ile Glu Gln 625 630 635 640 Leu Lys Gln Trp Ile Gly His Arg Thr Leu Ile Ile Ala Thr His Arg 645 650 655 Thr Ala Met Leu Gln Leu Val Asp Arg Ile Ile Val Met Asp Gln Gly 660 665 670 Arg Ile Val Met Asp Gly Ala Lys Glu Ala Ile Leu Arg Glu Gln Gly 675 680 685 Glu Pro Thr Ala Arg Arg Val Val Leu Gln Glu Lys Asn Lys Gly Ser 690 695 700 Ala Ala * 705 <210> 1060 <211> 24199 <212> DNA <213> Escherichia coli O157:H7 <400> 1060 ctttaagaag gactacaacc ggacagtagc aataaataca gccacttacg gacacaagcc 60 agacagtagt cggactgaaa aaagacaaaa atatacacgt gaaatgcacg tgcacttcta 120 aaaaacccca gttatcaccg actggggttt ttcaatttgt aactaagggt aacaaccccc 180 ccgttttttt catctcactc accttgatac tgtttatttg tacagttaaa aataatactg 240 tatacaaaca cagtatagag ggacttttat gcgtattgag atctgcatag ccaaagaaaa 300 aatgactaaa atgccaaacg gtgctgtgga tgcgttaaag gaagaattaa cccgacgcat 360 cagtaaacgt tatgacgatg tagaggtgat cgtaaaagcc accagcaacg atggcctttc 420 tgttacgcgc accgccgata aagattcagc taaaactttt gttcaggaga ctctgaaaga 480 tacctggaag tctgctgacg agtggtttgt tcactaatta acacgtaaaa tcggtaacgg 540 ctggaaatca ttcaatactc gcactatcga aagttcacca gccaaccgca gcacgtcctg 600 catacgtcgt gtctgcggtt tttctttttc gcttacattg tgtctggttc ttccggccac 660 tcaatatcag gtgcagttga tgtatcaaca cggttcagca acacccgata ctttttctag 720 gcttccagca atgaggtttc ttcctccgtt gcaatttcca gatctgcagc atcctgaagt 780 ggggcgcacc acgcaaacat cacaaaatat tgtcgctgcg atgaacctgt acaataaata 840 atgaatcacg gtacgtttct gtgtataacg tactgtagtt ttctttacga tttatagctg 900 tactggtgag ccatgagtaa tctgaatcca tgcatggcgt gtggtgccgt tgtgcatttt 960 ctgcgtctct tttactggtc cgaagccgat gatgctgaag cagtcctctc ctctagcctc 1020 atccctgtat agcacgcatc aaataatctg ggatatcatt tcgtagtttt acaatatcaa 1080 tatccgaatc gatatgtttc tggtaaaact tgtccgcaag caagtttgct atggtatctg 1140 atgtacgatt ttttacatcc cggctcatac catcacaaag agcatccatt ttcttgccaa 1200 aagaagcact ccccattatt acatgattaa tagaactttg tgctgcctta acatcaaggg 1260 ttagttgatt ctcctggctc acaagaaaaa agactctttg cctctcttca gtggaaattt 1320 ttgcattttt ttgaaaacag taattatcaa tctcctggtt gatcaccctt gagggatata 1380 ctatccgttc atcttttatc cactcatcaa tatctttagt actctgcctt ctcaccgttt 1440 ccagtatatt gccgctaaat ttgcgaacag aaaagctaat agtccgttct ccaattgaac 1500 attttacgac ctcatcattc ttccctcgga aagagttcct gaaggagttc tctctatggc 1560 aacttatacc aaaagagctg aaagacatac ctgtagtatt catcggcatt ataattcctt 1620 tttataaaaa agtgtttaca atattgcata cttgcgttta ttgtagccag aaaaaacatg 1680 catgcaataa tattctatta aaaattgtat tgttttattc acatatcatg agcggcatgt 1740 tgattcttgt taccaatata gttcacaata tggattaaaa aggataataa tatgccagtc 1800 atattaaatt tttctaatgg aagtgtattg ccggaaaatg agctggaggc tttacgacat 1860 atagcaagaa gcaaccagaa tgacactatt actataggag gccgtaatat gaggcttcat 1920 tatatccagt ttatggatgg ttttagtgtt gagcctattc ttggtggact ttgggaccat 1980 cttggggcaa gagaggctca tcatctcgca gaccgcctga caagacaact taacggaggt 2040 aacacttttc tgcaggcata cagcttatat ctggagcaga ggcaagctgc cccgcttgtg 2100 caggagagcg tcataaaaac actactagat cgaataaatt cgaatgcatt tcccgttagt 2160 ttacaagact tttcctgtac tgaggaacat cttaattgtc cgataacgct acatattcct 2220 gagacaggtg tttttgtcag aaatgctcga aattcagaaa tatgtgcatt atatgatcag 2280 gaagcattga ctgaacttat cctgcgtaac gctctccacc ccctcagccg tgaccccttt 2340 gctccagaaa tgattataag caaagacaag tgtcatttta atataacaaa acaatgtttt 2400 tacgcattac ccatataccc acttcaacaa aacagtattt aaaaataaaa gcacaatata 2460 agaagcatat tttcaataag ttaatcacca tataacaaac atatagcgag gagactattt 2520 atgcccaaaa tatcatcagt tgtatcatca tgttaccatc tgttcagtga acatcaacaa 2580 ctttcaaatg aaacaacaat gacgaacccc gtctccagaa gaattgttca taaagaatat 2640 ggtatatctt taaaatccgt tcctgtatgg ttggctacag ctaaaactcc ccttgctcta 2700 ctcaatggca gacatacaag aagtcactca tttattattg cagggacccc aggaatggga 2760 agcaggagcg gagcccaata ctatgccata aacagtgatg ataaacgctc ccgaatagac 2820 attgactctt tatttttaaa aaagttaaat aatgtgcgaa atcaaaataa atttccaatc 2880 gatgtaaaag aaacggttat aaaactacaa gggcaaaaat tcacatgcat tgaagatttt 2940 tataaaaggt ataatgaaac caggttaaag gccaatacca atatccaaca agaacaaatt 3000 gcagatgaag taaaatcact tacatatttg attccttcag aaaaaaaaga gatgtggata 3060 tataaaaaca atggaaaaga taatgcaaaa ccaaacttag gagagcgaga cgtaagaatg 3120 ttcgaaaata ttagttctga tgatacagat aagataacag gaaggaaatt ttcagagtta 3180 ggtgagtatc tttattcagg gaatgtaata aaactcagtc agttatcaat tcgttactta 3240 cccaatatca gctcaatctc attaatagag acaaaacaga gtttgttgct acatcgattg 3300 tattcagatg aagtacttca gagaaatgga acgcttatcc cgacaccact acatgaagaa 3360 aaatcaattc cagctgacaa tataaaaaca atgctcaaca acataccgac ttacaaaatg 3420 ttaccgccat tcacagaaac acaaggtaat tgttcttctg gcgcagccac gtttttacgc 3480 aaatcaggcg ccgaagaaaa agatattctt gcatgtagcc cccgaaatta tgggctgcat 3540 cataacataa aaacatggga ccccttggtt agaaattaag gatccaaata ttatatattt 3600 catataaagc aagaaaaaaa tattgtctga ataattgttc agacaatata tccttacatg 3660 gcactattat aataaactat taatataaaa acacaccaac aaaaaaaatt aagcatcact 3720 tgcaacaaag gattcttttt ttgaatcaaa gtgacattcg tcttttctca taatcattga 3780 ttctgttata ggttctcgac tcagaggatg agctccacca gtttcaacaa gttgcactaa 3840 cgtgtcctta tcatatagag agcatatctc agcaccttgt gagtttctca tgaacactcc 3900 attcgcaggt gtgtccagcg ttatcgggca tgtcaaaaat gactccgggc aagaaaagtg 3960 attagaatcc gttccaaata cacaggaatt tattttttcc attaatattt tattacttgt 4020 tttattttct ctgtgttctg ccatgacact ctgaaaatag ttattaacac tccttaaaaa 4080 atcgacacct ccatttaatt gcctttccag agccacagcc cttctctcca ttcgattctc 4140 acgccccaat agcctatcca gtagatttgc ccctatattt ccagacacct gttattaaat 4200 attcattcca aacacaggga gtcataacaa acatccaccg tacatgacaa caaaaaccgg 4260 agccggactc cggttttgtg aagctgtcgg gttacttcat cccgccaata ttttcccacg 4320 tcccgtcagc acgcaggatt tgcagcggtc ttaccacgca ctgtatctgc tttttatccg 4380 catccagtat caccacctgc gtgattaccc tggcctgctc cgggataatg ccattctcat 4440 ctgactccag gatgtctgcc ggccccagtc gcagctgtgc tgtaagtaac tccccgtgtt 4500 cacggtcatc atgctttccg caaccgcaca gacgctgcat aagttttttt agtatattca 4560 tgtcattctc ctgttctgcc tgtatcactg cccacttcat ccagcccctt aacatcctgc 4620 cacggcccgt caccaaacct gacctgcaaa tgctgaaaaa aaccctgaac ccgtgtggca 4680 tctttggggg caagaaaggt cagtccggtg atgagtgcgc catctgaacc gccccggaaa 4740 tcctggagac taaactccct gagaaagagg taaacaggat gactaaaaat actcgttttt 4800 cccccgaagt ccgtcagcgg gcgattcgta tggttctgga aagtcaggat gaatatgact 4860 cacagtgggc ggcaatttgt tccattgccc caaagattgg ctgtacgccg gagactctgc 4920 gtgtctgggt tcgccagcat gagcgggata ccgggggcgg tgatggtggg ctcaccagcg 4980 ctgaacgtca gcgtctgaaa gagctggaac gtgaaaatcg tgaactgcgc cgcagtaacg 5040 atatccttcg ccaggcttcc gcttattttg cgaaggcgga gttcgaccgc ctctggaaaa 5100 aatgatgcca ctgctggata agctgcgtga gcagtacggg gtcggaccgg tatgcagcga 5160 actgcatatt gccccgtcaa cgtattacca ttgtcagcaa cagcgacatc atccggataa 5220 acgcagtgcc cgtgcgcagc acgacgactg gctgaagaga gagatacagc gcgtatacga 5280 tgaaaatcat caggtgtacg gtgtgcgtaa agtctggcgt cagttgttac gggaaggaat 5340 cagggtggcc agatgtacag tggcacgtct catggcggtt atgggacttg ccggtgttct 5400 ccggggtaaa aaggtccgta cgaccatcag ccggaaagcc gttgccgcag gcgaccgcgt 5460 aaaccgtcag ttcgtggcag aacgacctga ccagctgtgg gtggctgatt ttacttacgt 5520 cagcacatgg cagggcttcg tctatgtggc gtttatcatt gatgtgtttg ccggatacat 5580 cgtggggtgg cgggtctcat cgtctatgga aacgacattc gtgctggatg cgctggagca 5640 ggcgttgtgg gcccgtcgtc cgtctggcac catccatcac agcgataaag gctctcagta 5700 tgtgtcactg gcctatacgg agcgactaaa agaagccgga ttactggcat caacagggag 5760 tacaggcgac tcgtatgaca acgcgatggc tgagagcatc aatggtcttt acaaagcgga 5820 ggtaatacac cgtaagagct ggaaaaaccg tgcagaagtg gaactggcca cactaacgtg 5880 ggtggactgg tataacaatc gacgattgct gggaaggctg ggccatactc ctccggcaga 5940 agcagaaaaa gcttattatg cttccatcgg aaacgatgat ctggcagcct gagttcacag 6000 ataaaacact ctccaggaaa accggggcgg ttcagttcgg cggtatcctc gcccagatag 6060 ctcagtgaac cgccgcagtt cgggcagcac ggcgccgcag gcaacagtcg cttttcgtca 6120 cggggtagtg attcagggaa cggcttacgg gtgcgggtct gacgcaacgg acgctgtact 6180 gccgggtcat acaccctacc agtcagcgta tcgctctctt tctgaagccg gttcagatcg 6240 gcttccattt gtgcgatacg gcgggagact ttttcggaac gactgccgaa gttcatccgg 6300 cggagtttat ccagctgcgc ctgcagatgg tctatttcgc gctcccggtt gctcagcttt 6360 tcctgcaggg cgtggatcag cgcttcctgt tcggccaggc gctgtttcag caggaagatg 6420 tcgtcagaag agatgtcgtt cataagcccg tattttaccg ggcttattct gtgacaacca 6480 ggataaagag atttacagca tggtcaggga ggtcagcagc cgcttaggct gtcgccagtc 6540 gataccttcc agcagcatcg ccagctgcgc ctgcgtaagg aacactttgc catcacgggc 6600 tgacggccag gcgaagcgcc cacgctccag ccgtttggtc aggaggcaca gtccgtcacc 6660 ggtggaccac agcagtttaa cctgactgcc gctgcggccc cggaaaatga aaacatggcc 6720 ggacatggga tcgtctttca gcgccgtttg tactttcgca gccaggccgt tgaagccatt 6780 tctcatatcg gtgataccgg caaccagcca aattttggtc ccggaaggta acgggatcat 6840 cgcttcagtt cctgtatcag cagagtcagg agcttttcgc tgacattgcc attgaagcgg 6900 agcgtcccgt gccggaacgt tacctcacag ctgatactga gggtttccgg gtcctctgcg 6960 agcgattctg gctgttcggc agctgcatcg agagtcacag gaagtagctg ggggctctct 7020 gaagaaggta atagcagctt tccctcgcgc cattgttgtc gccatttgaa caacagattg 7080 gcgttaatgc cattttcaag agcaagtttt gagatggata tcccgggttc acaggaggca 7140 gcaacgagct gctgtttaaa ttcgggagga taattagggc agccttttcg cctgccggga 7200 gtcacatttt tctgcatatc tgatactttg gttcccacta cttatttggt ggacaccact 7260 ttgtctaatt cgtcagattc tgaccagacg gttcaggctg tacgcttacc cttcgacagc 7320 ttcatgccag gaatcacagg cttaccatcc acccgggtgg ctccacggca gatggtccag 7380 atacccgcac catcacggta tgctgtggtg tggttacctt ccttttcatc cagaaactgg 7440 tcgaggattt caggcgcaga cgcccctgca ccaatcagcg ccagaacggc agccgacagg 7500 ccgtatctga tttttgcgtt catggatatt tatcagggtt tatcgatttc aaatccctgg 7560 atatgttaag tcttcaggcc agcggtggag tcttcagaga acccgtaatt attcccggta 7620 gttttcctct gtaggttatc aacacatcct gcgcctctaa aattacggga cgcttttccg 7680 gtaacggacc atccccttca cataacccgg cagcaacatc catgaaaaac tgcttcgcct 7740 gctttttcgc ctcagcttcg taaaactcca gcgtggcacc ttcagtacgg tcaagactaa 7800 tcgccacatc tggcaacaac agtgacggat acccaccaat ttccagtgcc acagtaacag 7860 taatcttatc cgggtaatta tttatccctt taacaaccag ttcgtatttt ttcttcatca 7920 ctttactctc cccgcgccgc cttacgccgg tcttctttaa tcttgaaata caggttcgtc 7980 agatatgtca gcagcccaaa cagcagactc cccagcacgc ctatcgccac ccactgggac 8040 ggagagactt tgtccagcag ctgcagtaac cagtatcccg tccccaccgc tgacgtggtg 8100 tatgacacac ccgttgtgat tttttccatc tggtacatac cccgtctccc gttatccgga 8160 agctgacaac aataaaaaag ccaccagtta actactgatg gctctgataa ctcatgcagg 8220 cgtctcagac gacccactga cactaccggt gagtttaacg ataccttcca tttgactggc 8280 tcacttttta tgatgatgcc ggtgcattta tctccagcac cagactttct atctcaacgc 8340 catacgctgc attttttgta acatccgtca gcgtcagcgc attcagtccc agtgtcatac 8400 tgtcttttat aacctggaat gccgggccag ccactccatt cagtttcgga gtaaccgtgg 8460 cactgccggc ggtgaacacc agctccagcg tctgccagtc gttaccgtaa tcgccgaact 8520 cccccagctt cgtgtttccg gctttcctgt gatgcatcag attcactctg ccgtcagtgg 8580 tctgagtgaa gtacgacatc aggaacggat taccggtacc cgtcatcgcc acaccatcag 8640 gaacgggagc atccgtatac agataaatcc ccagcccgaa ctgattgttg gtcagtgcgc 8700 ctgacaggcg gaacttacag gtcagtctgc cgccctgtgt cagcagggta attgcgtcat 8760 ccaccggatg cgtcagggac caggttttat tgctctgcct ggtgatctta aatacaccat 8820 ctgacaactg aattccgcca tccttaatgc tccagccctg cgcagcagcc tctccggctg 8880 ccggcagcag ggagattgtg cgaacggacg tatctgcaga cggacccgat ggcgtgttgc 8940 cgccgggcga gggtttgatt tccggtgcct taccactgat gaaggctgag gtgcgcccgg 9000 ctgcgttcag aatagcggtt gccatacgat ccggaataat gctcctgcgc gcccatgaac 9060 tgaaatgtgt cgggcggttt gatgatacct ggtttccatt cgttctcgat gccgcaccgt 9120 aatatcctga tgccggaata tccggatctt ctgccggcgc gttagtggcg gtattgacgc 9180 cgttaccgtc tgtcatgaag ggcacaaaat aaacgccctc actctccctg tttttgtacg 9240 ccccgtaaat ggtgttgtac tgggtgccgt aggtattttt ccagtaatac gtcgtgtcac 9300 cacaaatcca cggcacatct gcagcactgc caccatggca ctgcgcgtta aacacggaga 9360 ggtcagcacg aaactgtgcc agcatggctg taaacagcgc aggttgctgt gcgtgggtgg 9420 cggcgctcat gtcaaactct ccctgcatcc agcacaccgc cagcaacaca tttttcgggt 9480 tcttctgtaa tgcagcttta gtgcgcgcaa tcaggtcctg atataacggt ttacccacac 9540 cccagcgcgc cgaatcctgg ctggcccccg cgtccgcact gaatgtcccc tccgcgccct 9600 gggtgaatgc cgaaccacca cgacagcatg gtaccagcag gatccccgcg ttattcggga 9660 tatacggaag cagttttttg gcaatatgta agccctggcc gacacagccg tactgccctt 9720 tgctcaggtc tgccttcgga tgattcagcg tactcatatc ctgcacatca tgcaggcagt 9780 ggtcggccgg aataatatcg ttatatctgc aggcagcccc acccggcgta actgtactgc 9840 ggcgcgccag ctgtttaatg cgcggatccg gagcatcgta tgaatccggc agcggaagcc 9900 cttcaccgta agccatggca ttggactgcc cggccagtac gatgacgtag taccaatccg 9960 gctcagttgc accactgacc accacatcac cttctgctgt aatcacctgc atcagggtat 1002 0 aaggggttat ggccaccgga ctaccaaacg gctgccagcc ctctttcagt ttgtgtgtca 1008 0 gcttttccgc aaggtctgac ggcgacgccg ccctgacaac atcataatgt ttaaatgtca 1014 0 ttattcctcc cggccgggat agtgtattaa atcagatatg gagtgggctg tagtccggaa 1020 0 gcctgaatga cacacgggga ctacagccca agaaatgaaa aaaggccacg cagttgcgca 1026 0 gcctgataaa ccctggttaa aatccacacg ataacaacac aacaatatca gtatctcatg 1032 0 ctattgcccg aacccattcg ggcatttttt acccataaaa aatgcccctc cggagagggg 1038 0 catgtttgca tgcacattct ttttcttgca tggtgccggg tgcctcccgg tgaattcagt 1044 0 atcagcacct gaatccgcga ttatcacata tacctggttg ctgattgccc ctccgcacag 1050 0 ggggattcac catgcagtag tatttttaat aaacagtaaa caaaaaaatc aagcattatg 1056 0 caggctgttt ctttttatca ccggccacag caataccaca atgccgcaga ccagagcgcc 1062 0 atcagtcagt accaacatta tcctgctggt gaaatccatc atcaccatca ctaaaagcag 1068 0 gatcacaaca gcaagcagac acagtttata aaacaatgtt cagaaaacgc attcagcatg 1074 0 cctaaggttc tattcctacg aatagccaac ttgcaactta aaatattatt tatgcagcca 1080 0 attaaattct ggtccttaca atatcaacct gaagattctt atcttgtgct gattgataaa 1086 0 tcacaaacct tttactacct gcattgaaag aagtagacaa aaccagacaa ttatcataac 1092 0 gagcaagaac ataataccaa ccatcattat aattaatcat ttcatattct ttcttaaact 1098 0 gcggtttgta atatcctgtc agaaatgaaa aaagccagaa atatgccaca aaagcaatca 1104 0 tcacaatctc aaaaaaatgt ttttttataa atggcttatc atagaagcat gataccgata 1110 0 aaaatcgccc ataagatctt atcgaaattg tgaccgccag cgcaatcgct gctgacagta 1116 0 gcaaaagagg tacctgaatc ttctgtctca atatagaaaa ctcaataatt gccggcacaa 1122 0 acaataattc cacagcaaaa taaaggcgaa atacatttag ctcttgcata gaatgttttc 1128 0 ttttcactgc gaaaaagaat acaacaccaa taccccaacc gataagaaat atagcaatga 1134 0 cgataactgc aaaaaataaa cttctggcaa catcatcaac acctgcacct acaatccacc 1140 0 atgggaagcc gtagtaaaaa gaagtacccc atccatagaa ataagcactc ccccatccaa 1146 0 ggcatcccat gtaggcaata aaaagtgaag aactcctgag cagcgcacca tccttcataa 1152 0 ccaccccaat acaagatgat aacattggct tacaactcat aacaaaagca attcaatgcc 1158 0 gtcaagaggt tacaggctaa aaaaactcta ttacattgca gtcagcatgt ttactacaca 1164 0 aatacaattc agagcataaa aactactcgg cggcaggtta ttgagactca tcaatgacat 1170 0 gtaaaaaacg cccattattg gtgtcaagtt tccccaaagt tattcaaaaa gtcaatatta 1176 0 tgccgttaat atgttgccat ccgtggcaat catggcgcta acgtgtgatc gcattcaaaa 1182 0 tgttgtctgc gattgactct tccttgtggc attgcacaac cagagcgtca tacagcggct 1188 0 taacagtgcg tgaccaggtg ggttgggtaa ggtttgggat tagcatcgtc acagcgcgat 1194 0 atgcggcgct tgctggcatt cttgaataac cgacgccttt acatcttccg cactctttct 1200 0 cagcaactat cccccactgc tctgttttgg ctatatcaac cgcacggcct gtaccgtggc 1206 0 aatctctgca tcttgcgccc ggcgtagcgg cactacggca ataatccgca taagcgaatg 1212 0 ttgcgagcac ttgcagtacc tttgccttag tatttccttc aagctttgcc acgccacggt 1218 0 atttccccga taccttgtgt gcaaattgca tcagatagtt gatagccttt tgtttgtcgt 1224 0 tctggctgag ttcgtgctta ccacagaata cagccattcc gaatccggct tgtgattgcg 1230 0 ccatccccat agcagccatc acatcagtac cggaaagaga gtcagaagcc gtggcccgtg 1236 0 gtgagtcgct catcatcggg ctttttggcg aatgaaattt agctacgctt tcgagtctca 1242 0 tgcgccttct ccctgtacct gaatcaatgt gaggtttccg cagaacactg cgccagtatc 1248 0 gatatacatc tggttggcaa atttgagtgg tttcactgct ggcgtatgac caaagatgaa 1254 0 cgtgtccgcg cctttgattt ctttcacgat cccgtcttgt gagttgctga ttcgttcgcg 1260 0 gttccagatt acctgctgat gatcaactgg ctttccaaac tcgtatttat cacaaggata 1266 0 atcggcgtgg cagatgacat atttttttcc tttactcacc agttcgatga ttaacggaag 1272 0 ttcatctgct ttatgggcaa gagctttagc cagaatttct ttgtcgtaat cgagattaaa 1278 0 gaaccagcca ccgccattaa gcagccagtg attgacgttt ccacgctctg ataagccatc 1284 0 aatcatcatt tgctcatggt ttccacgtac agctctgaac caggggaatg tgattaattc 1290 0 caggcattct acgttctctg taccgcgatc aaccaaatcg cccaccgaga taagcaggtc 1296 0 ttttttggtg tcgaatccta tcgtctccag ttttttcatc aggttcgtgt agcatccgtg 1302 0 cagatcgcca actacccaaa tatttcggta tttgctgcca tcaattcttt cgtagatatt 1308 0 catgcaacct cacttctgct gtttcgcagt tttttaagtt tctgttgata ctccgccttg 1314 0 atggccctgc actcttcgac agtccagcga tagcggttat ggtttgattc gatttcctct 1320 0 actgcttcct gcccgatgcg gctaatcagt tcgacgcgat acggaacgag atttccgctt 1326 0 ttgtgctggt tgcacaccac gcattgcttg tgaatattgc gttcatcaaa tcggagttga 1332 0 ggtgccgcag cagttgtccg gtaatgtccg gcatcccact gagcagacgt gagcgttccg 1338 0 cacgagatac atggtaagtc gcggtctctt tctctgatga aggcgtgtac ggcttgttgg 1344 0 gcttgtttaa tccagtaact gcggggcttt aaggcgagtt tttgaatctt aagtttatct 1350 0 ttctgtttct gctcctctcg tcgtcgtttc ttctctgctg ccttttctgc cttttccgct 1356 0 ttttcgcgtt ctttacttcg tcgttcgagt gctatcttgg ttccacaaat ctcattacac 1362 0 caatattgat tttgatattt tggtataaac cattcattgc aacatttaca tttccttcga 1368 0 tagattcgca taagtgctcc tttcgttgcc ggaaaaatca ccgtaatact tatctcgggc 1374 0 ttcttcagca actagtaccg ctaactccag atcatcaaag catccgaagt gtttactctt 1380 0 gccatggaat cctagcctaa cattccattt tttctgtcgt ttgtgccaag taacccctct 1386 0 gcaacctgat ttgctattct ttcggatcct tatatttctt gaattttcta ttggcaggca 1392 0 ttctcttaaa ttttctggcc tattgtcggt cctaattcca ttaacgtggt caatttgacc 1398 0 agcaggccaa cgattatgag ttatgtaaaa aactaagacg tgagttttat atctacgccc 1404 0 atctatcatg atcattgaat aaccgttgga atcaaaagct ccagcaacac tatttaatgc 1410 0 tatccttccc tgagtgggaa ctttccatct aaataccccg gtagatttat cgaaacttag 1416 0 taactcaaat atccttttaa cagttaaatc ttctctttta cggttacatc gtcttcgcgc 1422 0 tggtttagcc atcgccttct tcctccgtaa tggttttctg aatttggcca cctgaacaga 1428 0 gctcaccaaa gctatggatg tcggtatttc cacaatacca agatggcgaa aataactgca 1434 0 tgataagcct cagggaaaag ggaagacact acccccgata attcagaaac aaatcgaaat 1440 0 acatgaacta aagaaaaaat cacaacaaat agaaatagaa atagaaatag aaatagaaat 1446 0 agaaatagaa atagaaatag aaatattaaa acagaccact gtagattcaa ttggtcaacg 1452 0 caacagttat gtgaaaacat ggggttgcgg agtttttttg aatgagacga acatttacag 1458 0 cagaggaaaa agcctctgtt tttgaactat ggaagaacgg aacaggcttc agtgaaatag 1464 0 cgaatatcct gggttcaaaa cccggaacga tcttcactat gttaagggat actggcggca 1470 0 taaaacccca tgagcgtaag cgggctgtag ctcacctgac actgtctgag cgcgaggaga 1476 0 tacgagctgg tttgtcagcc aaaatgagca ttcgtgcgat agctactgcg ctgaatcgca 1482 0 gtccttcgac gatctcacgt gaagttcagc gtaatcgggg cagacgctat tacaaagctg 1488 0 ttgatgctaa taaccgagcc aacagaatgg cgaaaaggcc aaaaccgtgc ttactggatc 1494 0 aaaatttacc attgcgaaag cttgttctgg aaaagctgga gatgaaatgg tctccagagc 1500 0 aaatatcagg atggttaagg cgaacaaaac cacgtcaaaa aacgctgcga atatcacctg 1506 0 agacaattta taaaacgctg tactttcgta gccgtgaagc gctacaccac ctgaatatac 1512 0 agcatctgcg acggtcgcat agccttcgcc atggcaggcg tcatacccgc aaaggcgaaa 1518 0 gaggtacgat taacatagtg aacggaacac caattcacga acgttcccga aatatcgata 1524 0 acagacgctc tctagggcat tgggagggcg atttagtctc aggtacaaaa aactctcata 1530 0 tagattcgtt tttctgacct tggcaggttg ttcttcagta ggcaaccagt cattgaaaaa 1536 0 tgagacgcag gaaagtgtga aaaccaaaat tgttaaaggc aaaactacaa aacaggacgt 1542 0 gttagcatcg ttcggtgaac ctgacagccg ttctttgatc gatggtgaag aacaatggtc 1548 0 atacactatg tataacagcc agtccaaagc aacctctttc atccccgttg tgggactgct 1554 0 tgcaggtggc gcagactcac aaactaaatc tctgacagtt tctttcaaag gcgaaaaagt 1560 0 cagcacatac atctttaatg ctggaacaag caacgtgaag actggcattt tttagataaa 1566 0 agacaaaacc agcatcaagg gaaaatttag cccgcagttg atacctacgg gctttttaca 1572 0 gaaacataaa tcacttttta aagaaagtga ttatcttttt cagcctcctg caaactttac 1578 0 tgttcatttc tacagtctca gtattttcct ttaaagagga tcttattggc tctggctctg 1584 0 gctctggctc tggctctggc tctggctctg gctctggctc tggctctggc tctggctctg 1590 0 gctctggctc tggctctggc tctggctctg gctctggctc tggctctggc tctggctctg 1596 0 gctctggctc tggctctggc aaaggagaac taaaatctaa tgaagtttca atattatatt 1602 0 catgattttt atggtctata tcagataatg aaatgggttg ttcattcaat gatgatacag 1608 0 acagatcatt ttcaatgtaa taattactat cattatatga gctttcaaat ttacccaaga 1614 0 aagccacata tactaattta aagtggtttg tcttaaatag aaacttatca ttttcatccg 1620 0 gcatcccaaa aaagaaaacc gtcaagtatt ttttagcatt ccttttatct ttaagcccct 1626 0 tataatacct atcagcttcc ttcctttgct tttcatattc cttccaaaac acatccttct 1632 0 gacttttatt ccagtcagaa acatcaattt caagcgtaaa tggtttttgg gttttcttat 1638 0 cccttgcgag gaaagtaata caatgtttat ctgaatcttc atgcagacga atattagact 1644 0 gggctacacc ataataaata gcaggtttgt aataacgtat gttgtttttg taaaaaataa 1650 0 gttgaaatgt atctttataa gatcgcgtgc catatggagg gattgatagc tgttcattat 1656 0 gattgctatt atttatgtaa tagtcaacga ctggcttaat acttgatgaa gatacaggat 1662 0 gttcattacc ttttttttca tccttgtgat tttcattttt aatatttctg gcatttttaa 1668 0 caccacctct tggtttcaca tcaattttta aaagtgatat aaccggagca ggtggcgaat 1674 0 tatgttttct ttcgtcattt gaagtatgat tgtttttata tcttggatca tgaataccac 1680 0 atccatcctt atgtttatcg ccatatctga aatatgattg attaacatgt ttcatagtaa 1686 0 aactacaagg tgtggcttta attttacaag gctcgtatgg gcattcaaaa ctcgttgtct 1692 0 taatgtaaaa atcatccatt ccacggagat catttccatg aatgatttca tcagtcgaac 1698 0 tatccttcgc aatcgtcata tcttaaccct atgaaaatct atgtccttct aaggattcta 1704 0 gctttttctt attgacgatc caatcaaaaa attgtactcc aacttaccaa aatacacgat 1710 0 caagcagaag ttattaactt aaggggtaga attagtattt ttcaaagaaa ttaaatcttt 1716 0 gacagaatga tgctgaataa catcgctaac cttagtaagg tcagggagtt gttatacaca 1722 0 actcccctct attatcgttt gttaaaggtt ctgggtatgt atgcatggta acagtaaaag 1728 0 catcttagag gatgctttta agcattaatt agattcatgg aattatagat ttacgaatct 1734 0 aatattaaaa tttagactat agattaagta agtctaatga aaatcataca aacactacaa 1740 0 cctatatctt ttccttttat cctttttcga taattctctt tttagagttg aagcctcata 1746 0 tttccttttc tcattagcat agactttctc tgttcggcta ccattactga ctataaagtt 1752 0 aatcaatgaa gaacatacat gcttcatacg ctctttgttg atcaaatcat catccagttt 1758 0 atttatatga ctataatatg aaagtagcag aaaggttaaa acaacctccc tgttggagaa 1764 0 ggtcattttt tctataccac tctggtattt gatataaaat cctgcacaaa aaagatatga 1770 0 ttgttcgata attcgttgct ctgagaaacc tgattcagcg agtttatcaa cgaatcgatc 1776 0 aagcagaaga agataccttt ccattaagtt aatatttgtt ttgtccataa tatgcatcct 1782 0 tgcaatagtg aaattttgtc gtcctgacaa gaaaataaat aacataatat ttcaccatgt 1788 0 caatagctaa aacctatcaa ttttattaaa ggtattttgc aggtaacgga ttattaagtt 1794 0 cttcaatcgt tatttgttta aggtgagcat tataaagcca tactttgaac tgctctaaat 1800 0 agcgttcatt taatgccttc aaagcttcat tttctgcttc aagtctttta attcgttgag 1806 0 aagccacttt taaattagca ggttttacag tgtgtattac accagatttg attgtggttt 1812 0 ttttcacatt gaagctttcc gcaatcctta catgactact taaggattgt cttgatggtc 1818 0 ttttcccaat aaccctgact aacctatcgc acaaagcatt ccaggttagt ttttcatcta 1824 0 tagaccatgt gttaataaca tctacaatct tcttctcatg ataaccattt atatgcttag 1830 0 ccatttattc tccttttttt atttttttat ggaattcata ccatttatca gcatttatgt 1836 0 tcccatcatt tttatcatac agtgttcttt ttaaaatttt atcgtggata tttgaaatcg 1842 0 tttcgttatc taaaccagag ttcttaattg gataattatc acacggctta aacgcatatg 1848 0 agtgcttgca gtagccatgt tttgatacaa gtactgcacc actactaagt gagtcaaact 1854 0 cattaagatc cactactgga atatccttta ttctgtgctc attaacacat actgataact 1860 0 ttttttctct tattgcttta gacatttgaa gatgcgatct gtggtcataa gaaacatttt 1866 0 gagaaataag cttacgtcca gaccagcgag caatactaaa ttcatccata ccatttattt 1872 0 gagcaaatgt gttgagaaga tgccttagtt gatgtgttct tagcaaatat gggctaccat 1878 0 cttcatttat ataaccatgt cttttaaaaa cattaaaata cccttttata taatcagaat 1884 0 caatgatatc agttttaaaa aaattcgttg taggtctgaa taatttatct gacatttcct 1890 0 ttttattttg atttaactgt ccttcagtta acaagcaaag cgcattagaa tatttgattt 1896 0 tcttctctct atcataccaa aagagatcag gaggtatatt ttctttaagg gttcccttcg 1902 0 ttgaattaga gtaattcttt tgaatttcag cagccaataa cctcgcttga cttgataatt 1908 0 cttttaatct gctaatagcc tttttagcta caggtatcat taaagttgga atccatttta 1914 0 tattgccttc ataccctttt gctgaaaaaa atcttaaacc gtatctttga atgccctttc 1920 0 catcacattc tgtgatttca caatccgctg gcaaagctaa aatttccgat atcctactcg 1926 0 gtgcacacat aagtaaagca agcacagatg tagtaaatat atctcttgac gataattgtt 1932 0 catcccgctt tgaaaaaatc tcagcaatcg caataactga tttgatatca ggcaatctag 1938 0 aatggccttc cagtgaagaa tcataaccag tccaagactg agtaatccta tacctaattg 1944 0 gatttaccca aaataaataa aatgagttag tcatcctatt atcatttaaa aatgaactca 1950 0 atttctcaag ttctttccca atagcaaatg catgtgcttt agaatacttt tcagaggcta 1956 0 tccttatgca ttcatcatag attgaattgt tgcaatagtt tacattagct tccatattga 1962 0 ttttaagtaa aacgaattcg acaatcttca acattgataa tgttgagtgt ttcgtcttag 1968 0 atttattgaa tgaatgcaca tgcaacatat atgctttagc aaaattaata aagctatcat 1974 0 ctaagcactc cttgctgttt aggttgtttt ttgagttaaa cttagtaaac ctatataaac 1980 0 ctttccattt attgctttcc catgaagttg ttaaattatt attagaaata gtactcttac 1986 0 aaaactcgat aaacttaata acattatcga gagggttgtt tttattgctt ggttcaaaaa 1992 0 taaatatatt gttcataatg ctctccaggg attgaatttt ttacacgtta aacatttcaa 1998 0 atcctctttc gtatcttcca ataagaaaaa tgcatctgaa acaaacttga taaaaaagtt 2004 0 cttgttttct tcaatctcta tgcccataag tatattagat aaggggttaa aaaacgcact 2010 0 tagtctctta tcgatgtcat aaacgttgtc aggattattt tttatatata ttatagaaga 2016 0 gtttactgat ttatgatcta acgctttagc aatcacctca attgaggctc cttcattagc 2022 0 cagtcgactt cctaacgtat atctgaatct tctagcatta agttctatat agctgttagt 2028 0 cctttctgac ctaacatcga attttgacgg aaagtgtttt aatagttttg acataactga 2034 0 atttttcata tggaaaaaat ctgttgttaa atcatataaa aaatcctcaa tcctttttgt 2040 0 ttccgtaatc ttatctaaat tcatgaagat tggtaattcg cctctatagt tactaatccc 2046 0 aacactgaat ttatcttcaa caaacgcctg attttgatta attagcattg ataagctgtc 2052 0 atataagaac ggctctatca taaccatgtt aaattctttt ctgaaacatt ttctttgttt 2058 0 tacttttggt acattcaaaa agcaccctct ctcattttta atgagatctt tagcttttag 2064 0 agatattaat tgtaatggcc ttcttcctgt tattgccagc aaaaggatat aacaatacaa 2070 0 aaagcattga attttcttct catgataaaa ttttccaacg gcgttaatga tgttattgaa 2076 0 ttccgcttca gttaaaggtc ctttatttgg atctcgtctt ttaactgcat ctcctgtttg 2082 0 gtttggaatg atttttattt tctccagcat tctaatggca gtcgcttcta ccccagggta 2088 0 attgagattt ttccatttaa tgatgaaagc cttaattaag tttagtttgt agtttctttc 2094 0 tgaacctaaa taaacattca attgatatat tgctttgtca tcaatagtat cgatagtcat 2100 0 cgcaccaaac cactcataaa atagattgtt aatactttga atataaaaag aactatattc 2106 0 agacgcatag taagccaatg tttttaagta gctaagtttc atttttgtag gcattctatc 2112 0 tacaacttta tgagggtata cgcagttttc tttatccagt tgccatttct tatctgacag 2118 0 tttgaaacta tacctgttca tcttagcaaa aaagatttgc tcactttcaa tacatttgtt 2124 0 ttccatacta aactccacta attattttac ttactgattt atagaccttt aggacgacat 2130 0 ccttctcttg ttgcgatata tatttatagt tgtatctatc acacattatt gactcctttg 2136 0 accaacccat taaataattc cttaaatctt tccttctatt atattctaat tcagcacctt 2142 0 ctattccttt agaatacata taattccaag agtgccttaa cctatggcct gaaagattat 2148 0 atagctctgg acttgctcgt ttcagtgttg atatcacctt ctcataagct gaaatgctta 2154 0 agggttctcc tgcgtttttt ccggtgcaat gagccacaaa taagaaatta tgctttttcc 2160 0 tttttgtcat tttttctctg ctattgctta tgtaatcaaa aatttcacgg gctaactcat 2166 0 cagataacgg aataaccctt tctccagtct ttactaatgg ttgataagat cttccatctt 2172 0 cttttgaatc atgtcttctg actacactta aagtgttgtc tctgagatca aaatcatcta 2178 0 ttttaagatt gagcaactct ccagccctta aacctaaatt taagagcaag gtaaatatta 2184 0 gtctgttcct gacctgtact tccttatgga aagggttttc aatcccgcca atttccaata 2190 0 gacggaaaag cactttgatc tcttcttcat tcaacgattt ttcagatatt tcattcatat 2196 0 tcaatgaact gtttcttgga atatgtgctc tgatactttc aataaatacg tctacttcat 2202 0 actttgcatg aatccccttt gacgaatgaa ctaatccaca taaccactta aggtagcgtg 2208 0 aaaaaacgtg tattctataa ctaaaggttc tcttcgcaat aaacctataa tttgtcgatt 2214 0 ttatatttat gattttttgt ctgtcgaatc tttgtttcgc atatcttacc agatcatcta 2220 0 tttctgcaac gctgagatat tttttaagtt caactctctc aattatatca attcccctac 2226 0 catccaagaa attactgaaa attagtaagt tagttgcaac tatttccatc gttgaggccg 2232 0 ttgcgcctct atttcttatg tctgtagtaa gaaatagatt ttgatagtaa gttggtagat 2238 0 tacttttttt atcaaggatc aggcatcctc gctctccact actcatgatg aatttcttta 2244 0 ctttatatcc cattttcacc tcaaacttaa caaattaata tcactctaac ttattaaata 2250 0 tattccaatt caaaataatt caaatttttt acaatgaatc ttgtttaatt ggtatatata 2256 0 ttaatggctt gaaaaatttt atttgacgtc aaataaacag gtacggctag tgggctgtat 2262 0 ccatacccga tattaagaaa accatctcta agccttatag caaaagctct gccagaaaaa 2268 0 acgtaaagaa ttacgttaaa tatagatttt tttaagattt aaactttaca aatctgagaa 2274 0 ttaatcctca taaataagaa gactgtcatt ttatttcagg caacatgctt tcttgaattt 2280 0 tcgatagtta attgaatcca ttcgtctact tcactttcaa tgaaagcaac agagcgcgca 2286 0 ccgattttaa cgggggaagg aaaacgattt tggttgatga ggtgatagat ccaagcttta 2292 0 ccgtatccag ttcgatgcag aacctctggt aaacgaataa ggcgggtgtt gtgctgattc 2298 0 atagtcgttt cctctgtgcc gttttgatgg aaatgactat acaaatgaat cagcaggaaa 2304 0 aagaccgaag ctgggaacgc cagagctaat ggaggttggt cttagtcaga atcagcgatt 2310 0 ttcatcacgt ctgaaactct gatctttttc aaatggctgt tcttgttgat gaacagatta 2316 0 aactggcgaa taaaaggtat actcgccgcc ttcaaagcaa gaggtttgtc tgtatccctg 2322 0 atttggtggt tcaggcgagt gttgatctca tcatcgtcat ctgtatacaa caggcgagaa 2328 0 aggcggtctt ctgatatacg tactttatat aattttgacc ataccagaat gtcgatcatg 2334 0 ggaaggagtc tgtaattaat gattttctta atcgttccat aaccaaagcg aatagcttcc 2340 0 gttacatctg gttctatgcc acgcacttta cgccattgag gaagtgcagc ctttagggat 2346 0 tcagcgatct cttcatctgt cccgtttgct aggtcgattt cgaccatgac agtatccctg 2352 0 aacaattttg gcaaaacttc cgatacaggg ctatcgagga attctctgtt aacagaatac 2358 0 tcatcgcttc catcccaaaa aaacagtgag ttccgtaatc caactatgct gagttgagcc 2364 0 agtctttcgg ttgtcgtcaa aaagaagtgc gggggctggt aaagagtatc ctctcttgtg 2370 0 agatagccga gatgcttttc tgtgatgaga aagggctttc cagtgaagat cctgtcgatg 2376 0 tagagcctta cggcttctgc ttcaaattct tcatgatatg gtttgaagaa caatgtcctt 2382 0 gccagcaatt catggtagag gtgtataagc ggaagctctt cgaatccgcg atatgtatct 2388 0 atatccagcc acttcttcac ctctctcgta tgttcaactg accagttttt cataacgatc 2394 0 tccaacaggc attagactta atgtatgtag caaacgtaat cgacatgtta aaggaagacc 2400 0 aatgaaatga gttcagatgc catcaggaag ttgaaccaaa aggtttgata ttttttgata 2406 0 cagttcgcta acggactatt ttcaggggtt tatgccgtta cgatttatgg ttcctttata 2412 0 gaaccaaagg taaagtcaga aacagcagtt atctagaaaa ttcaatcaaa tagatatcta 2418 0 gttacaggga cgccagcca 2419 9 <210> 1061 <211> 83 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(269..517) <400> 1061 Met Arg Ile Glu Ile Cys Ile Ala Lys Glu Lys Met Thr Lys Met Pro 1 5 10 15 Asn Gly Ala Val Asp Ala Leu Lys Glu Glu Leu Thr Arg Arg Ile Ser 20 25 30 Lys Arg Tyr Asp Asp Val Glu Val Ile Val Lys Ala Thr Ser Asn Asp 35 40 45 Gly Leu Ser Val Thr Arg Thr Ala Asp Lys Asp Ser Ala Lys Thr Phe 50 55 60 Val Gln Glu Thr Leu Lys Asp Thr Trp Lys Ser Ala Asp Glu Trp Phe 65 70 75 80 Val His * <210> 1062 <211> 54 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(680..841) <400> 1062 Met Tyr Gln His Gly Ser Ala Thr Pro Asp Thr Phe Ser Arg Leu Pro 1 5 10 15 Ala Met Arg Phe Leu Pro Pro Leu Gln Phe Pro Asp Leu Gln His Pro 20 25 30 Glu Val Gly Arg Thr Thr Gln Thr Ser Gln Asn Ile Val Ala Ala Met 35 40 45 Asn Leu Tyr Asn Lys * 50 <210> 1063 <211> 197 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1019..1609) <400> 1063 Met Pro Met Asn Thr Thr Gly Met Ser Phe Ser Ser Phe Gly Ile Ser 1 5 10 15 Cys His Arg Glu Asn Ser Phe Arg Asn Ser Phe Arg Gly Lys Asn Asp 20 25 30 Glu Val Val Lys Cys Ser Ile Gly Glu Arg Thr Ile Ser Phe Ser Val 35 40 45 Arg Lys Phe Ser Gly Asn Ile Leu Glu Thr Val Arg Arg Gln Ser Thr 50 55 60 Lys Asp Ile Asp Glu Trp Ile Lys Asp Glu Arg Ile Val Tyr Pro Ser 65 70 75 80 Arg Val Ile Asn Gln Glu Ile Asp Asn Tyr Cys Phe Gln Lys Asn Ala 85 90 95 Lys Ile Ser Thr Glu Glu Arg Gln Arg Val Phe Phe Leu Val Ser Gln 100 105 110 Glu Asn Gln Leu Thr Leu Asp Val Lys Ala Ala Gln Ser Ser Ile Asn 115 120 125 His Val Ile Met Gly Ser Ala Ser Phe Gly Lys Lys Met Asp Ala Leu 130 135 140 Cys Asp Gly Met Ser Arg Asp Val Lys Asn Arg Thr Ser Asp Thr Ile 145 150 155 160 Ala Asn Leu Leu Ala Asp Lys Phe Tyr Gln Lys His Ile Asp Ser Asp 165 170 175 Ile Asp Ile Val Lys Leu Arg Asn Asp Ile Pro Asp Tyr Leu Met Arg 180 185 190 Ala Ile Gln Gly * 195 <210> 1064 <211> 217 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1792..2442) <400> 1064 Met Pro Val Ile Leu Asn Phe Ser Asn Gly Ser Val Leu Pro Glu Asn 1 5 10 15 Glu Leu Glu Ala Leu Arg His Ile Ala Arg Ser Asn Gln Asn Asp Thr 20 25 30 Ile Thr Ile Gly Gly Arg Asn Met Arg Leu His Tyr Ile Gln Phe Met 35 40 45 Asp Gly Phe Ser Val Glu Pro Ile Leu Gly Gly Leu Trp Asp His Leu 50 55 60 Gly Ala Arg Glu Ala His His Leu Ala Asp Arg Leu Thr Arg Gln Leu 65 70 75 80 Asn Gly Gly Asn Thr Phe Leu Gln Ala Tyr Ser Leu Tyr Leu Glu Gln 85 90 95 Arg Gln Ala Ala Pro Leu Val Gln Glu Ser Val Ile Lys Thr Leu Leu 100 105 110 Asp Arg Ile Asn Ser Asn Ala Phe Pro Val Ser Leu Gln Asp Phe Ser 115 120 125 Cys Thr Glu Glu His Leu Asn Cys Pro Ile Thr Leu His Ile Pro Glu 130 135 140 Thr Gly Val Phe Val Arg Asn Ala Arg Asn Ser Glu Ile Cys Ala Leu 145 150 155 160 Tyr Asp Gln Glu Ala Leu Thr Glu Leu Ile Leu Arg Asn Ala Leu His 165 170 175 Pro Leu Ser Arg Asp Pro Phe Ala Pro Glu Met Ile Ile Ser Lys Asp 180 185 190 Lys Cys His Phe Asn Ile Thr Lys Gln Cys Phe Tyr Ala Leu Pro Ile 195 200 205 Tyr Pro Leu Gln Gln Asn Ser Ile * 210 215 <210> 1065 <211> 353 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2521..3579) <400> 1065 Met Pro Lys Ile Ser Ser Val Val Ser Ser Cys Tyr His Leu Phe Ser 1 5 10 15 Glu His Gln Gln Leu Ser Asn Glu Thr Thr Met Thr Asn Pro Val Ser 20 25 30 Arg Arg Ile Val His Lys Glu Tyr Gly Ile Ser Leu Lys Ser Val Pro 35 40 45 Val Trp Leu Ala Thr Ala Lys Thr Pro Leu Ala Leu Leu Asn Gly Arg 50 55 60 His Thr Arg Ser His Ser Phe Ile Ile Ala Gly Thr Pro Gly Met Gly 65 70 75 80 Ser Arg Ser Gly Ala Gln Tyr Tyr Ala Ile Asn Ser Asp Asp Lys Arg 85 90 95 Ser Arg Ile Asp Ile Asp Ser Leu Phe Leu Lys Lys Leu Asn Asn Val 100 105 110 Arg Asn Gln Asn Lys Phe Pro Ile Asp Val Lys Glu Thr Val Ile Lys 115 120 125 Leu Gln Gly Gln Lys Phe Thr Cys Ile Glu Asp Phe Tyr Lys Arg Tyr 130 135 140 Asn Glu Thr Arg Leu Lys Ala Asn Thr Asn Ile Gln Gln Glu Gln Ile 145 150 155 160 Ala Asp Glu Val Lys Ser Leu Thr Tyr Leu Ile Pro Ser Glu Lys Lys 165 170 175 Glu Met Trp Ile Tyr Lys Asn Asn Gly Lys Asp Asn Ala Lys Pro Asn 180 185 190 Leu Gly Glu Arg Asp Val Arg Met Phe Glu Asn Ile Ser Ser Asp Asp 195 200 205 Thr Asp Lys Ile Thr Gly Arg Lys Phe Ser Glu Leu Gly Glu Tyr Leu 210 215 220 Tyr Ser Gly Asn Val Ile Lys Leu Ser Gln Leu Ser Ile Arg Tyr Leu 225 230 235 240 Pro Asn Ile Ser Ser Ile Ser Leu Ile Glu Thr Lys Gln Ser Leu Leu 245 250 255 Leu His Arg Leu Tyr Ser Asp Glu Val Leu Gln Arg Asn Gly Thr Leu 260 265 270 Ile Pro Thr Pro Leu His Glu Glu Lys Ser Ile Pro Ala Asp Asn Ile 275 280 285 Lys Thr Met Leu Asn Asn Ile Pro Thr Tyr Lys Met Leu Pro Pro Phe 290 295 300 Thr Glu Thr Gln Gly Asn Cys Ser Ser Gly Ala Ala Thr Phe Leu Arg 305 310 315 320 Lys Ser Gly Ala Glu Glu Lys Asp Ile Leu Ala Cys Ser Pro Arg Asn 325 330 335 Tyr Gly Leu His His Asn Ile Lys Thr Trp Asp Pro Leu Val Arg Asn 340 345 350 * <210> 1066 <211> 141 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3709..4131) <400> 1066 Met Glu Arg Arg Ala Val Ala Leu Glu Arg Gln Leu Asn Gly Gly Val 1 5 10 15 Asp Phe Leu Arg Ser Val Asn Asn Tyr Phe Gln Ser Val Met Ala Glu 20 25 30 His Arg Glu Asn Lys Thr Ser Asn Lys Ile Leu Met Glu Lys Ile Asn 35 40 45 Ser Cys Val Phe Gly Thr Asp Ser Asn His Phe Ser Cys Pro Glu Ser 50 55 60 Phe Leu Thr Cys Pro Ile Thr Leu Asp Thr Pro Ala Asn Gly Val Phe 65 70 75 80 Met Arg Asn Ser Gln Gly Ala Glu Ile Cys Ser Leu Tyr Asp Lys Asp 85 90 95 Thr Leu Val Gln Leu Val Glu Thr Gly Gly Ala His Pro Leu Ser Arg 100 105 110 Glu Pro Ile Thr Glu Ser Met Ile Met Arg Lys Asp Glu Cys His Phe 115 120 125 Asp Ser Lys Lys Glu Ser Phe Val Ala Ser Asp Ala * 130 135 140 <210> 1067 <211> 130 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4292..4681) <400> 1067 Met Pro His Gly Phe Arg Val Phe Phe Ser Ile Cys Arg Ser Gly Leu 1 5 10 15 Val Thr Gly Arg Gly Arg Met Leu Arg Gly Trp Met Lys Trp Ala Val 20 25 30 Ile Gln Ala Glu Gln Glu Asn Asp Met Asn Ile Leu Lys Lys Leu Met 35 40 45 Gln Arg Leu Cys Gly Cys Gly Lys His Asp Asp Arg Glu His Gly Glu 50 55 60 Leu Leu Thr Ala Gln Leu Arg Leu Gly Pro Ala Asp Ile Leu Glu Ser 65 70 75 80 Asp Glu Asn Gly Ile Ile Pro Glu Gln Ala Arg Val Ile Thr Gln Val 85 90 95 Val Ile Leu Asp Ala Asp Lys Lys Gln Ile Gln Cys Val Val Arg Pro 100 105 110 Leu Gln Ile Leu Arg Ala Asp Gly Thr Trp Glu Asn Ile Gly Gly Met 115 120 125 Lys * <210> 1068 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4779..5105) <400> 1068 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1069 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5102..5992) <400> 1069 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 1070 <211> 166 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5799..6296) <400> 1070 Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala Gln 1 5 10 15 Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu Thr 20 25 30 Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr Arg 35 40 45 Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg Leu 50 55 60 Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser Tyr 65 70 75 80 Leu Gly Glu Asp Thr Ala Glu Leu Asn Arg Pro Gly Phe Pro Gly Glu 85 90 95 Cys Phe Ile Cys Glu Leu Arg Leu Pro Asp His Arg Phe Arg Trp Lys 100 105 110 His Asn Lys Leu Phe Leu Leu Leu Pro Glu Glu Tyr Gly Pro Ala Phe 115 120 125 Pro Ala Ile Val Asp Cys Tyr Thr Ser Pro Pro Thr Leu Val Trp Pro 130 135 140 Val Pro Leu Leu His Gly Phe Ser Ser Ser Tyr Gly Val Leu Pro Pro 145 150 155 160 Leu Cys Lys Asp His * 165 <210> 1071 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6493..6840) <400> 1071 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Asp Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 1072 <211> 127 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6837..7217) <400> 1072 Met Gln Lys Asn Val Thr Pro Gly Arg Arg Lys Gly Cys Pro Asn Tyr 1 5 10 15 Pro Pro Glu Phe Lys Gln Gln Leu Val Ala Ala Ser Cys Glu Pro Gly 20 25 30 Ile Ser Ile Ser Lys Leu Ala Leu Glu Asn Gly Ile Asn Ala Asn Leu 35 40 45 Leu Phe Lys Trp Arg Gln Gln Trp Arg Glu Gly Lys Leu Leu Leu Pro 50 55 60 Ser Ser Glu Ser Pro Gln Leu Leu Pro Val Thr Leu Asp Ala Ala Ala 65 70 75 80 Glu Gln Pro Glu Ser Leu Ala Glu Asp Pro Glu Thr Leu Ser Ile Ser 85 90 95 Cys Glu Val Thr Phe Arg His Gly Thr Leu Arg Phe Asn Gly Asn Val 100 105 110 Ser Glu Lys Leu Leu Thr Leu Leu Ile Gln Glu Leu Lys Arg * 115 120 125 <210> 1073 <211> 77 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7293..7523) <400> 1073 Met Asn Ala Lys Ile Arg Tyr Gly Leu Ser Ala Ala Val Leu Ala Leu 1 5 10 15 Ile Gly Ala Gly Ala Ser Ala Pro Glu Ile Leu Asp Gln Phe Leu Asp 20 25 30 Glu Lys Glu Gly Asn His Thr Thr Ala Tyr Arg Asp Gly Ala Gly Ile 35 40 45 Trp Thr Ile Cys Arg Gly Ala Thr Arg Val Asp Gly Lys Pro Val Ile 50 55 60 Pro Gly Met Lys Leu Ser Lys Gly Lys Arg Thr Ala * 65 70 75 <210> 1074 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7574..7918) <400> 1074 Met Lys Lys Lys Tyr Glu Leu Val Val Lys Gly Ile Asn Asn Tyr Pro 1 5 10 15 Asp Lys Ile Thr Val Thr Val Ala Leu Glu Ile Gly Gly Tyr Pro Ser 20 25 30 Leu Leu Leu Pro Asp Val Ala Ile Ser Leu Asp Arg Thr Glu Gly Ala 35 40 45 Thr Leu Glu Phe Tyr Glu Ala Glu Ala Lys Lys Gln Ala Lys Gln Phe 50 55 60 Phe Met Asp Val Ala Ala Gly Leu Cys Glu Gly Asp Gly Pro Leu Pro 65 70 75 80 Glu Lys Arg Pro Val Ile Leu Glu Ala Gln Asp Val Leu Ile Thr Tyr 85 90 95 Arg Gly Lys Leu Pro Gly Ile Ile Thr Gly Ser Leu Lys Thr Pro Pro 100 105 110 Leu Ala * <210> 1075 <211> 72 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7923..8138) <400> 1075 Met Tyr Gln Met Glu Lys Ile Thr Thr Gly Val Ser Tyr Thr Thr Ser 1 5 10 15 Ala Val Gly Thr Gly Tyr Trp Leu Leu Gln Leu Leu Asp Lys Val Ser 20 25 30 Pro Ser Gln Trp Val Ala Ile Gly Val Leu Gly Ser Leu Leu Phe Gly 35 40 45 Leu Leu Thr Tyr Leu Thr Asn Leu Tyr Phe Lys Ile Lys Glu Asp Arg 50 55 60 Arg Lys Ala Ala Arg Gly Glu * 65 70 <210> 1076 <211> 618 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8288..10141) <400> 1076 Met Thr Phe Lys His Tyr Asp Val Val Arg Ala Ala Ser Pro Ser Asp 1 5 10 15 Leu Ala Glu Lys Leu Thr His Lys Leu Lys Glu Gly Trp Gln Pro Phe 20 25 30 Gly Ser Pro Val Ala Ile Thr Pro Tyr Thr Leu Met Gln Val Ile Thr 35 40 45 Ala Glu Gly Asp Val Val Val Ser Gly Ala Thr Glu Pro Asp Trp Tyr 50 55 60 Tyr Val Ile Val Leu Ala Gly Gln Ser Asn Ala Met Ala Tyr Gly Glu 65 70 75 80 Gly Leu Pro Leu Pro Asp Ser Tyr Asp Ala Pro Asp Pro Arg Ile Lys 85 90 95 Gln Leu Ala Arg Arg Ser Thr Val Thr Pro Gly Gly Ala Ala Cys Arg 100 105 110 Tyr Asn Asp Ile Ile Pro Ala Asp His Cys Leu His Asp Val Gln Asp 115 120 125 Met Ser Thr Leu Asn His Pro Lys Ala Asp Leu Ser Lys Gly Gln Tyr 130 135 140 Gly Cys Val Gly Gln Gly Leu His Ile Ala Lys Lys Leu Leu Pro Tyr 145 150 155 160 Ile Pro Asn Asn Ala Gly Ile Leu Leu Val Pro Cys Cys Arg Gly Gly 165 170 175 Ser Ala Phe Thr Gln Gly Ala Glu Gly Thr Phe Ser Ala Asp Ala Gly 180 185 190 Ala Ser Gln Asp Ser Ala Arg Trp Gly Val Gly Lys Pro Leu Tyr Gln 195 200 205 Asp Leu Ile Ala Arg Thr Lys Ala Ala Leu Gln Lys Asn Pro Lys Asn 210 215 220 Val Leu Leu Ala Val Cys Trp Met Gln Gly Glu Phe Asp Met Ser Ala 225 230 235 240 Ala Thr His Ala Gln Gln Pro Ala Leu Phe Thr Ala Met Leu Ala Gln 245 250 255 Phe Arg Ala Asp Leu Ser Val Phe Asn Ala Gln Cys His Gly Gly Ser 260 265 270 Ala Ala Asp Val Pro Trp Ile Cys Gly Asp Thr Thr Tyr Tyr Trp Lys 275 280 285 Asn Thr Tyr Gly Thr Gln Tyr Asn Thr Ile Tyr Gly Ala Tyr Lys Asn 290 295 300 Arg Glu Ser Glu Gly Val Tyr Phe Val Pro Phe Met Thr Asp Gly Asn 305 310 315 320 Gly Val Asn Thr Ala Thr Asn Ala Pro Ala Glu Asp Pro Asp Ile Pro 325 330 335 Ala Ser Gly Tyr Tyr Gly Ala Ala Ser Arg Thr Asn Gly Asn Gln Val 340 345 350 Ser Ser Asn Arg Pro Thr His Phe Ser Ser Trp Ala Arg Arg Ser Ile 355 360 365 Ile Pro Asp Arg Met Ala Thr Ala Ile Leu Asn Ala Ala Gly Arg Thr 370 375 380 Ser Ala Phe Ile Ser Gly Lys Ala Pro Glu Ile Lys Pro Ser Pro Gly 385 390 395 400 Gly Asn Thr Pro Ser Gly Pro Ser Ala Asp Thr Ser Val Arg Thr Ile 405 410 415 Ser Leu Leu Pro Ala Ala Gly Glu Ala Ala Ala Gln Gly Trp Ser Ile 420 425 430 Lys Asp Gly Gly Ile Gln Leu Ser Asp Gly Val Phe Lys Ile Thr Arg 435 440 445 Gln Ser Asn Lys Thr Trp Ser Leu Thr His Pro Val Asp Asp Ala Ile 450 455 460 Thr Leu Leu Thr Gln Gly Gly Arg Leu Thr Cys Lys Phe Arg Leu Ser 465 470 475 480 Gly Ala Leu Thr Asn Asn Gln Phe Gly Leu Gly Ile Tyr Leu Tyr Thr 485 490 495 Asp Ala Pro Val Pro Asp Gly Val Ala Met Thr Gly Thr Gly Asn Pro 500 505 510 Phe Leu Met Ser Tyr Phe Thr Gln Thr Thr Asp Gly Arg Val Asn Leu 515 520 525 Met His His Arg Lys Ala Gly Asn Thr Lys Leu Gly Glu Phe Gly Asp 530 535 540 Tyr Gly Asn Asp Trp Gln Thr Leu Glu Leu Val Phe Thr Ala Gly Ser 545 550 555 560 Ala Thr Val Thr Pro Lys Leu Asn Gly Val Ala Gly Pro Ala Phe Gln 565 570 575 Val Ile Lys Asp Ser Met Thr Leu Gly Leu Asn Ala Leu Thr Leu Thr 580 585 590 Asp Val Thr Lys Asn Ala Ala Tyr Gly Val Glu Ile Glu Ser Leu Val 595 600 605 Leu Glu Ile Asn Ala Pro Ala Ser Ser * 610 615 <210> 1077 <211> 110 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10382..10711) <400> 1077 Met Phe Ala Cys Thr Phe Phe Phe Leu His Gly Ala Gly Cys Leu Pro 1 5 10 15 Val Asn Ser Val Ser Ala Pro Glu Ser Ala Ile Ile Thr Tyr Thr Trp 20 25 30 Leu Leu Ile Ala Pro Pro His Arg Gly Ile His His Ala Val Val Phe 35 40 45 Leu Ile Asn Ser Lys Gln Lys Asn Gln Ala Leu Cys Arg Leu Phe Leu 50 55 60 Phe Ile Thr Gly His Ser Asn Thr Thr Met Pro Gln Thr Arg Ala Pro 65 70 75 80 Ser Val Ser Thr Asn Ile Ile Leu Leu Val Lys Ser Ile Ile Thr Ile 85 90 95 Thr Lys Ser Arg Ile Thr Thr Ala Ser Arg His Ser Leu * 100 105 <210> 1078 <211> 248 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10802..11545) <400> 1078 Met Leu Ser Ser Cys Ile Gly Val Val Met Lys Asp Gly Ala Leu Leu 1 5 10 15 Arg Ser Ser Ser Leu Phe Ile Ala Tyr Met Gly Cys Leu Gly Trp Gly 20 25 30 Ser Ala Tyr Phe Tyr Gly Trp Gly Thr Ser Phe Tyr Tyr Gly Phe Pro 35 40 45 Trp Trp Ile Val Gly Ala Gly Val Asp Asp Val Ala Arg Ser Leu Phe 50 55 60 Phe Ala Val Ile Val Ile Ala Ile Phe Leu Ile Gly Trp Gly Ile Gly 65 70 75 80 Val Val Phe Phe Phe Ala Val Lys Arg Lys His Ser Met Gln Glu Leu 85 90 95 Asn Val Phe Arg Leu Tyr Phe Ala Val Glu Leu Leu Phe Val Pro Ala 100 105 110 Ile Ile Glu Phe Ser Ile Leu Arg Gln Lys Ile Gln Val Pro Leu Leu 115 120 125 Leu Leu Ser Ala Ala Ile Ala Leu Ala Val Thr Ile Ser Ile Arg Ser 130 135 140 Tyr Gly Arg Phe Leu Ser Val Ser Cys Phe Tyr Asp Lys Pro Phe Ile 145 150 155 160 Lys Lys His Phe Phe Glu Ile Val Met Ile Ala Phe Val Ala Tyr Phe 165 170 175 Trp Leu Phe Ser Phe Leu Thr Gly Tyr Tyr Lys Pro Gln Phe Lys Lys 180 185 190 Glu Tyr Glu Met Ile Asn Tyr Asn Asp Gly Trp Tyr Tyr Val Leu Ala 195 200 205 Arg Tyr Asp Asn Cys Leu Val Leu Ser Thr Ser Phe Asn Ala Gly Ser 210 215 220 Lys Arg Phe Val Ile Tyr Gln Ser Ala Gln Asp Lys Asn Leu Gln Val 225 230 235 240 Asp Ile Val Arg Thr Arg Ile * 245 <210> 1079 <211> 208 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11798..12421) <400> 1079 Met Arg Leu Glu Ser Val Ala Lys Phe His Ser Pro Lys Ser Pro Met 1 5 10 15 Met Ser Asp Ser Pro Arg Ala Thr Ala Ser Asp Ser Leu Ser Gly Thr 20 25 30 Asp Val Met Ala Ala Met Gly Met Ala Gln Ser Gln Ala Gly Phe Gly 35 40 45 Met Ala Val Phe Cys Gly Lys His Glu Leu Ser Gln Asn Asp Lys Gln 50 55 60 Lys Ala Ile Asn Tyr Leu Met Gln Phe Ala His Lys Val Ser Gly Lys 65 70 75 80 Tyr Arg Gly Val Ala Lys Leu Glu Gly Asn Thr Lys Ala Lys Val Leu 85 90 95 Gln Val Leu Ala Thr Phe Ala Tyr Ala Asp Tyr Cys Arg Ser Ala Ala 100 105 110 Thr Pro Gly Ala Arg Cys Arg Asp Cys His Gly Thr Gly Arg Ala Val 115 120 125 Asp Ile Ala Lys Thr Glu Gln Trp Gly Ile Val Ala Glu Lys Glu Cys 130 135 140 Gly Arg Cys Lys Gly Val Gly Tyr Ser Arg Met Pro Ala Ser Ala Ala 145 150 155 160 Tyr Arg Ala Val Thr Met Leu Ile Pro Asn Leu Thr Gln Pro Thr Trp 165 170 175 Ser Arg Thr Val Lys Pro Leu Tyr Asp Ala Leu Val Val Gln Cys His 180 185 190 Lys Glu Glu Ser Ile Ala Asp Asn Ile Leu Asn Ala Ile Thr Arg * 195 200 205 <210> 1080 <211> 222 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12418..13083) <400> 1080 Met Asn Ile Tyr Glu Arg Ile Asp Gly Ser Lys Tyr Arg Asn Ile Trp 1 5 10 15 Val Val Gly Asp Leu His Gly Cys Tyr Thr Asn Leu Met Lys Lys Leu 20 25 30 Glu Thr Ile Gly Phe Asp Thr Lys Lys Asp Leu Leu Ile Ser Val Gly 35 40 45 Asp Leu Val Asp Arg Gly Thr Glu Asn Val Glu Cys Leu Glu Leu Ile 50 55 60 Thr Phe Pro Trp Phe Arg Ala Val Arg Gly Asn His Glu Gln Met Met 65 70 75 80 Ile Asp Gly Leu Ser Glu Arg Gly Asn Val Asn His Trp Leu Leu Asn 85 90 95 Gly Gly Gly Trp Phe Phe Asn Leu Asp Tyr Asp Lys Glu Ile Leu Ala 100 105 110 Lys Ala Leu Ala His Lys Ala Asp Glu Leu Pro Leu Ile Ile Glu Leu 115 120 125 Val Ser Lys Gly Lys Lys Tyr Val Ile Cys His Ala Asp Tyr Pro Cys 130 135 140 Asp Lys Tyr Glu Phe Gly Lys Pro Val Asp His Gln Gln Val Ile Trp 145 150 155 160 Asn Arg Glu Arg Ile Ser Asn Ser Gln Asp Gly Ile Val Lys Glu Ile 165 170 175 Lys Gly Ala Asp Thr Phe Ile Phe Gly His Thr Pro Ala Val Lys Pro 180 185 190 Leu Lys Phe Ala Asn Gln Met Tyr Ile Asp Thr Gly Ala Val Phe Cys 195 200 205 Gly Asn Leu Thr Leu Ile Gln Val Gln Gly Glu Gly Ala * 210 215 220 <210> 1081 <211> 204 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13080..13691) <400> 1081 Met Arg Ile Tyr Arg Arg Lys Cys Lys Cys Cys Asn Glu Trp Phe Ile 1 5 10 15 Pro Lys Tyr Gln Asn Gln Tyr Trp Cys Asn Glu Ile Cys Gly Thr Lys 20 25 30 Ile Ala Leu Glu Arg Arg Ser Lys Glu Arg Glu Lys Ala Glu Lys Ala 35 40 45 Glu Lys Ala Ala Glu Lys Lys Arg Arg Arg Glu Glu Gln Lys Gln Lys 50 55 60 Asp Lys Leu Lys Ile Gln Lys Leu Ala Leu Lys Pro Arg Ser Tyr Trp 65 70 75 80 Ile Lys Gln Ala Gln Gln Ala Val His Ala Phe Ile Arg Glu Arg Asp 85 90 95 Arg Asp Leu Pro Cys Ile Ser Cys Gly Thr Leu Thr Ser Ala Gln Trp 100 105 110 Asp Ala Gly His Tyr Arg Thr Thr Ala Ala Ala Pro Gln Leu Arg Phe 115 120 125 Asp Glu Arg Asn Ile His Lys Gln Cys Val Val Cys Asn Gln His Lys 130 135 140 Ser Gly Asn Leu Val Pro Tyr Arg Val Glu Leu Ile Ser Arg Ile Gly 145 150 155 160 Gln Glu Ala Val Glu Glu Ile Glu Ser Asn His Asn Arg Tyr Arg Trp 165 170 175 Thr Val Glu Glu Cys Arg Ala Ile Lys Ala Glu Tyr Gln Gln Lys Leu 180 185 190 Lys Lys Leu Arg Asn Ser Arg Ser Glu Val Ala * 195 200 <210> 1082 <211> 189 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13666..14232) <400> 1082 Met Ala Lys Pro Ala Arg Arg Arg Cys Asn Arg Lys Arg Glu Asp Leu 1 5 10 15 Thr Val Lys Arg Ile Phe Glu Leu Leu Ser Phe Asp Lys Ser Thr Gly 20 25 30 Val Phe Arg Trp Lys Val Pro Thr Gln Gly Arg Ile Ala Leu Asn Ser 35 40 45 Val Ala Gly Ala Phe Asp Ser Asn Gly Tyr Ser Met Ile Met Ile Asp 50 55 60 Gly Arg Arg Tyr Lys Thr His Val Leu Val Phe Tyr Ile Thr His Asn 65 70 75 80 Arg Trp Pro Ala Gly Gln Ile Asp His Val Asn Gly Ile Arg Thr Asp 85 90 95 Asn Arg Pro Glu Asn Leu Arg Glu Cys Leu Pro Ile Glu Asn Ser Arg 100 105 110 Asn Ile Arg Ile Arg Lys Asn Ser Lys Ser Gly Cys Arg Gly Val Thr 115 120 125 Trp His Lys Arg Gln Lys Lys Trp Asn Val Arg Leu Gly Phe His Gly 130 135 140 Lys Ser Lys His Phe Gly Cys Phe Asp Asp Leu Glu Leu Ala Val Leu 145 150 155 160 Val Ala Glu Glu Ala Arg Asp Lys Tyr Tyr Gly Asp Phe Ser Gly Asn 165 170 175 Glu Arg Ser Thr Tyr Ala Asn Leu Ser Lys Glu Met * 180 185 <210> 1083 <211> 252 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14562..15317) <400> 1083 Met Arg Arg Thr Phe Thr Ala Glu Glu Lys Ala Ser Val Phe Glu Leu 1 5 10 15 Trp Lys Asn Gly Thr Gly Phe Ser Glu Ile Ala Asn Ile Leu Gly Ser 20 25 30 Lys Pro Gly Thr Ile Phe Thr Met Leu Arg Asp Thr Gly Gly Ile Lys 35 40 45 Pro His Glu Arg Lys Arg Ala Val Ala His Leu Thr Leu Ser Glu Arg 50 55 60 Glu Glu Ile Arg Ala Gly Leu Ser Ala Lys Met Ser Ile Arg Ala Ile 65 70 75 80 Ala Thr Ala Leu Asn Arg Ser Pro Ser Thr Ile Ser Arg Glu Val Gln 85 90 95 Arg Asn Arg Gly Arg Arg Tyr Tyr Lys Ala Val Asp Ala Asn Asn Arg 100 105 110 Ala Asn Arg Met Ala Lys Arg Pro Lys Pro Cys Leu Leu Asp Gln Asn 115 120 125 Leu Pro Leu Arg Lys Leu Val Leu Glu Lys Leu Glu Met Lys Trp Ser 130 135 140 Pro Glu Gln Ile Ser Gly Trp Leu Arg Arg Thr Lys Pro Arg Gln Lys 145 150 155 160 Thr Leu Arg Ile Ser Pro Glu Thr Ile Tyr Lys Thr Leu Tyr Phe Arg 165 170 175 Ser Arg Glu Ala Leu His His Leu Asn Ile Gln His Leu Arg Arg Ser 180 185 190 His Ser Leu Arg His Gly Arg Arg His Thr Arg Lys Gly Glu Arg Gly 195 200 205 Thr Ile Asn Ile Val Asn Gly Thr Pro Ile His Glu Arg Ser Arg Asn 210 215 220 Ile Asp Asn Arg Arg Ser Leu Gly His Trp Glu Gly Asp Leu Val Ser 225 230 235 240 Gly Thr Lys Asn Ser His Ile Asp Ser Phe Phe * 245 250 <210> 1084 <211> 132 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15260..15655) <400> 1084 Leu Gly Gly Arg Phe Ser Leu Arg Tyr Lys Lys Leu Ser Tyr Arg Phe 1 5 10 15 Val Phe Leu Thr Leu Ala Gly Cys Ser Ser Val Gly Asn Gln Ser Leu 20 25 30 Lys Asn Glu Thr Gln Glu Ser Val Lys Thr Lys Ile Val Lys Gly Lys 35 40 45 Thr Thr Lys Gln Asp Val Leu Ala Ser Phe Gly Glu Pro Asp Ser Arg 50 55 60 Ser Leu Ile Asp Gly Glu Glu Gln Trp Ser Tyr Thr Met Tyr Asn Ser 65 70 75 80 Gln Ser Lys Ala Thr Ser Phe Ile Pro Val Val Gly Leu Leu Ala Gly 85 90 95 Gly Ala Asp Ser Gln Thr Lys Ser Leu Thr Val Ser Phe Lys Gly Glu 100 105 110 Lys Val Ser Thr Tyr Ile Phe Asn Ala Gly Thr Ser Asn Val Lys Thr 115 120 125 Gly Ile Phe * 130 <210> 1085 <211> 423 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15731..16999) <400> 1085 Met Thr Ile Ala Lys Asp Ser Ser Thr Asp Glu Ile Ile His Gly Asn 1 5 10 15 Asp Leu Arg Gly Met Asp Asp Phe Tyr Ile Lys Thr Thr Ser Phe Glu 20 25 30 Cys Pro Tyr Glu Pro Cys Lys Ile Lys Ala Thr Pro Cys Ser Phe Thr 35 40 45 Met Lys His Val Asn Gln Ser Tyr Phe Arg Tyr Gly Asp Lys His Lys 50 55 60 Asp Gly Cys Gly Ile His Asp Pro Arg Tyr Lys Asn Asn His Thr Ser 65 70 75 80 Asn Asp Glu Arg Lys His Asn Ser Pro Pro Ala Pro Val Ile Ser Leu 85 90 95 Leu Lys Ile Asp Val Lys Pro Arg Gly Gly Val Lys Asn Ala Arg Asn 100 105 110 Ile Lys Asn Glu Asn His Lys Asp Glu Lys Lys Gly Asn Glu His Pro 115 120 125 Val Ser Ser Ser Ser Ile Lys Pro Val Val Asp Tyr Tyr Ile Asn Asn 130 135 140 Ser Asn His Asn Glu Gln Leu Ser Ile Pro Pro Tyr Gly Thr Arg Ser 145 150 155 160 Tyr Lys Asp Thr Phe Gln Leu Ile Phe Tyr Lys Asn Asn Ile Arg Tyr 165 170 175 Tyr Lys Pro Ala Ile Tyr Tyr Gly Val Ala Gln Ser Asn Ile Arg Leu 180 185 190 His Glu Asp Ser Asp Lys His Cys Ile Thr Phe Leu Ala Arg Asp Lys 195 200 205 Lys Thr Gln Lys Pro Phe Thr Leu Glu Ile Asp Val Ser Asp Trp Asn 210 215 220 Lys Ser Gln Lys Asp Val Phe Trp Lys Glu Tyr Glu Lys Gln Arg Lys 225 230 235 240 Glu Ala Asp Arg Tyr Tyr Lys Gly Leu Lys Asp Lys Arg Asn Ala Lys 245 250 255 Lys Tyr Leu Thr Val Phe Phe Phe Gly Met Pro Asp Glu Asn Asp Lys 260 265 270 Phe Leu Phe Lys Thr Asn His Phe Lys Leu Val Tyr Val Ala Phe Leu 275 280 285 Gly Lys Phe Glu Ser Ser Tyr Asn Asp Ser Asn Tyr Tyr Ile Glu Asn 290 295 300 Asp Leu Ser Val Ser Ser Leu Asn Glu Gln Pro Ile Ser Leu Ser Asp 305 310 315 320 Ile Asp His Lys Asn His Glu Tyr Asn Ile Glu Thr Ser Leu Asp Phe 325 330 335 Ser Ser Pro Leu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu 340 345 350 Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu 355 360 365 Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu 370 375 380 Pro Glu Pro Glu Pro Glu Pro Ile Arg Ser Ser Leu Lys Glu Asn Thr 385 390 395 400 Glu Thr Val Glu Met Asn Ser Lys Val Cys Arg Arg Leu Lys Lys Ile 405 410 415 Ile Thr Phe Phe Lys Lys * 420 <210> 1086 <211> 138 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17395..17808) <400> 1086 Met Asp Lys Thr Asn Ile Asn Leu Met Glu Arg Tyr Leu Leu Leu Leu 1 5 10 15 Asp Arg Phe Val Asp Lys Leu Ala Glu Ser Gly Phe Ser Glu Gln Arg 20 25 30 Ile Ile Glu Gln Ser Tyr Leu Phe Cys Ala Gly Phe Tyr Ile Lys Tyr 35 40 45 Gln Ser Gly Ile Glu Lys Met Thr Phe Ser Asn Arg Glu Val Val Leu 50 55 60 Thr Phe Leu Leu Leu Ser Tyr Tyr Ser His Ile Asn Lys Leu Asp Asp 65 70 75 80 Asp Leu Ile Asn Lys Glu Arg Met Lys His Val Cys Ser Ser Leu Ile 85 90 95 Asn Phe Ile Val Ser Asn Gly Ser Arg Thr Glu Lys Val Tyr Ala Asn 100 105 110 Glu Lys Arg Lys Tyr Glu Ala Ser Thr Leu Lys Arg Glu Leu Ser Lys 115 120 125 Lys Asp Lys Arg Lys Arg Tyr Arg Leu * 130 135 <210> 1087 <211> 133 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17906..18304) <400> 1087 Met Ala Lys His Ile Asn Gly Tyr His Glu Lys Lys Ile Val Asp Val 1 5 10 15 Ile Asn Thr Trp Ser Ile Asp Glu Lys Leu Thr Trp Asn Ala Leu Cys 20 25 30 Asp Arg Leu Val Arg Val Ile Gly Lys Arg Pro Ser Arg Gln Ser Leu 35 40 45 Ser Ser His Val Arg Ile Ala Glu Ser Phe Asn Val Lys Lys Thr Thr 50 55 60 Ile Lys Ser Gly Val Ile His Thr Val Lys Pro Ala Asn Leu Lys Val 65 70 75 80 Ala Ser Gln Arg Ile Lys Arg Leu Glu Ala Glu Asn Glu Ala Leu Lys 85 90 95 Ala Leu Asn Glu Arg Tyr Leu Glu Gln Phe Lys Val Trp Leu Tyr Asn 100 105 110 Ala His Leu Lys Gln Ile Thr Ile Glu Glu Leu Asn Asn Pro Leu Pro 115 120 125 Ala Lys Tyr Leu * 130 <210> 1088 <211> 544 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18305..19936) <400> 1088 Met Asn Asn Ile Phe Ile Phe Glu Pro Ser Asn Lys Asn Asn Pro Leu 1 5 10 15 Asp Asn Val Ile Lys Phe Ile Glu Phe Cys Lys Ser Thr Ile Ser Asn 20 25 30 Asn Asn Leu Thr Thr Ser Trp Glu Ser Asn Lys Trp Lys Gly Leu Tyr 35 40 45 Arg Phe Thr Lys Phe Asn Ser Lys Asn Asn Leu Asn Ser Lys Glu Cys 50 55 60 Leu Asp Asp Ser Phe Ile Asn Phe Ala Lys Ala Tyr Met Leu His Val 65 70 75 80 His Ser Phe Asn Lys Ser Lys Thr Lys His Ser Thr Leu Ser Met Leu 85 90 95 Lys Ile Val Glu Phe Val Leu Leu Lys Ile Asn Met Glu Ala Asn Val 100 105 110 Asn Tyr Cys Asn Asn Ser Ile Tyr Asp Glu Cys Ile Arg Ile Ala Ser 115 120 125 Glu Lys Tyr Ser Lys Ala His Ala Phe Ala Ile Gly Lys Glu Leu Glu 130 135 140 Lys Leu Ser Ser Phe Leu Asn Asp Asn Arg Met Thr Asn Ser Phe Tyr 145 150 155 160 Leu Phe Trp Val Asn Pro Ile Arg Tyr Arg Ile Thr Gln Ser Trp Thr 165 170 175 Gly Tyr Asp Ser Ser Leu Glu Gly His Ser Arg Leu Pro Asp Ile Lys 180 185 190 Ser Val Ile Ala Ile Ala Glu Ile Phe Ser Lys Arg Asp Glu Gln Leu 195 200 205 Ser Ser Arg Asp Ile Phe Thr Thr Ser Val Leu Ala Leu Leu Met Cys 210 215 220 Ala Pro Ser Arg Ile Ser Glu Ile Leu Ala Leu Pro Ala Asp Cys Glu 225 230 235 240 Ile Thr Glu Cys Asp Gly Lys Gly Ile Gln Arg Tyr Gly Leu Arg Phe 245 250 255 Phe Ser Ala Lys Gly Tyr Glu Gly Asn Ile Lys Trp Ile Pro Thr Leu 260 265 270 Met Ile Pro Val Ala Lys Lys Ala Ile Ser Arg Leu Lys Glu Leu Ser 275 280 285 Ser Gln Ala Arg Leu Leu Ala Ala Glu Ile Gln Lys Asn Tyr Ser Asn 290 295 300 Ser Thr Lys Gly Thr Leu Lys Glu Asn Ile Pro Pro Asp Leu Phe Trp 305 310 315 320 Tyr Asp Arg Glu Lys Lys Ile Lys Tyr Ser Asn Ala Leu Cys Leu Leu 325 330 335 Thr Glu Gly Gln Leu Asn Gln Asn Lys Lys Glu Met Ser Asp Lys Leu 340 345 350 Phe Arg Pro Thr Thr Asn Phe Phe Lys Thr Asp Ile Ile Asp Ser Asp 355 360 365 Tyr Ile Lys Gly Tyr Phe Asn Val Phe Lys Arg His Gly Tyr Ile Asn 370 375 380 Glu Asp Gly Ser Pro Tyr Leu Leu Arg Thr His Gln Leu Arg His Leu 385 390 395 400 Leu Asn Thr Phe Ala Gln Ile Asn Gly Met Asp Glu Phe Ser Ile Ala 405 410 415 Arg Trp Ser Gly Arg Lys Leu Ile Ser Gln Asn Val Ser Tyr Asp His 420 425 430 Arg Ser His Leu Gln Met Ser Lys Ala Ile Arg Glu Lys Lys Leu Ser 435 440 445 Val Cys Val Asn Glu His Arg Ile Lys Asp Ile Pro Val Val Asp Leu 450 455 460 Asn Glu Phe Asp Ser Leu Ser Ser Gly Ala Val Leu Val Ser Lys His 465 470 475 480 Gly Tyr Cys Lys His Ser Tyr Ala Phe Lys Pro Cys Asp Asn Tyr Pro 485 490 495 Ile Lys Asn Ser Gly Leu Asp Asn Glu Thr Ile Ser Asn Ile His Asp 500 505 510 Lys Ile Leu Lys Arg Thr Leu Tyr Asp Lys Asn Asp Gly Asn Ile Asn 515 520 525 Ala Asp Lys Trp Tyr Glu Phe His Lys Lys Ile Lys Lys Gly Glu * 530 535 540 <210> 1089 <211> 438 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19933..21246) <400> 1089 Met Glu Asn Lys Cys Ile Glu Ser Glu Gln Ile Phe Phe Ala Lys Met 1 5 10 15 Asn Arg Tyr Ser Phe Lys Leu Ser Asp Lys Lys Trp Gln Leu Asp Lys 20 25 30 Glu Asn Cys Val Tyr Pro His Lys Val Val Asp Arg Met Pro Thr Lys 35 40 45 Met Lys Leu Ser Tyr Leu Lys Thr Leu Ala Tyr Tyr Ala Ser Glu Tyr 50 55 60 Ser Ser Phe Tyr Ile Gln Ser Ile Asn Asn Leu Phe Tyr Glu Trp Phe 65 70 75 80 Gly Ala Met Thr Ile Asp Thr Ile Asp Asp Lys Ala Ile Tyr Gln Leu 85 90 95 Asn Val Tyr Leu Gly Ser Glu Arg Asn Tyr Lys Leu Asn Leu Ile Lys 100 105 110 Ala Phe Ile Ile Lys Trp Lys Asn Leu Asn Tyr Pro Gly Val Glu Ala 115 120 125 Thr Ala Ile Arg Met Leu Glu Lys Ile Lys Ile Ile Pro Asn Gln Thr 130 135 140 Gly Asp Ala Val Lys Arg Arg Asp Pro Asn Lys Gly Pro Leu Thr Glu 145 150 155 160 Ala Glu Phe Asn Asn Ile Ile Asn Ala Val Gly Lys Phe Tyr His Glu 165 170 175 Lys Lys Ile Gln Cys Phe Leu Tyr Cys Tyr Ile Leu Leu Leu Ala Ile 180 185 190 Thr Gly Arg Arg Pro Leu Gln Leu Ile Ser Leu Lys Ala Lys Asp Leu 195 200 205 Ile Lys Asn Glu Arg Gly Cys Phe Leu Asn Val Pro Lys Val Lys Gln 210 215 220 Arg Lys Cys Phe Arg Lys Glu Phe Asn Met Val Met Ile Glu Pro Phe 225 230 235 240 Leu Tyr Asp Ser Leu Ser Met Leu Ile Asn Gln Asn Gln Ala Phe Val 245 250 255 Glu Asp Lys Phe Ser Val Gly Ile Ser Asn Tyr Arg Gly Glu Leu Pro 260 265 270 Ile Phe Met Asn Leu Asp Lys Ile Thr Glu Thr Lys Arg Ile Glu Asp 275 280 285 Phe Leu Tyr Asp Leu Thr Thr Asp Phe Phe His Met Lys Asn Ser Val 290 295 300 Met Ser Lys Leu Leu Lys His Phe Pro Ser Lys Phe Asp Val Arg Ser 305 310 315 320 Glu Arg Thr Asn Ser Tyr Ile Glu Leu Asn Ala Arg Arg Phe Arg Tyr 325 330 335 Thr Leu Gly Ser Arg Leu Ala Asn Glu Gly Ala Ser Ile Glu Val Ile 340 345 350 Ala Lys Ala Leu Asp His Lys Ser Val Asn Ser Ser Ile Ile Tyr Ile 355 360 365 Lys Asn Asn Pro Asp Asn Val Tyr Asp Ile Asp Lys Arg Leu Ser Ala 370 375 380 Phe Phe Asn Pro Leu Ser Asn Ile Leu Met Gly Ile Glu Ile Glu Glu 385 390 395 400 Asn Lys Asn Phe Phe Ile Lys Phe Val Ser Asp Ala Phe Phe Leu Leu 405 410 415 Glu Asp Thr Lys Glu Asp Leu Lys Cys Leu Thr Cys Lys Lys Phe Asn 420 425 430 Pro Trp Arg Ala Leu * 435 <210> 1090 <211> 402 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21248..22453) <400> 1090 Met Gly Tyr Lys Val Lys Lys Phe Ile Met Ser Ser Gly Glu Arg Gly 1 5 10 15 Cys Leu Ile Leu Asp Lys Lys Ser Asn Leu Pro Thr Tyr Tyr Gln Asn 20 25 30 Leu Phe Leu Thr Thr Asp Ile Arg Asn Arg Gly Ala Thr Ala Ser Thr 35 40 45 Met Glu Ile Val Ala Thr Asn Leu Leu Ile Phe Ser Asn Phe Leu Asp 50 55 60 Gly Arg Gly Ile Asp Ile Ile Glu Arg Val Glu Leu Lys Lys Tyr Leu 65 70 75 80 Ser Val Ala Glu Ile Asp Asp Leu Val Arg Tyr Ala Lys Gln Arg Phe 85 90 95 Asp Arg Gln Lys Ile Ile Asn Ile Lys Ser Thr Asn Tyr Arg Phe Ile 100 105 110 Ala Lys Arg Thr Phe Ser Tyr Arg Ile His Val Phe Ser Arg Tyr Leu 115 120 125 Lys Trp Leu Cys Gly Leu Val His Ser Ser Lys Gly Ile His Ala Lys 130 135 140 Tyr Glu Val Asp Val Phe Ile Glu Ser Ile Arg Ala His Ile Pro Arg 145 150 155 160 Asn Ser Ser Leu Asn Met Asn Glu Ile Ser Glu Lys Ser Leu Asn Glu 165 170 175 Glu Glu Ile Lys Val Leu Phe Arg Leu Leu Glu Ile Gly Gly Ile Glu 180 185 190 Asn Pro Phe His Lys Glu Val Gln Val Arg Asn Arg Leu Ile Phe Thr 195 200 205 Leu Leu Leu Asn Leu Gly Leu Arg Ala Gly Glu Leu Leu Asn Leu Lys 210 215 220 Ile Asp Asp Phe Asp Leu Arg Asp Asn Thr Leu Ser Val Val Arg Arg 225 230 235 240 His Asp Ser Lys Glu Asp Gly Arg Ser Tyr Gln Pro Leu Val Lys Thr 245 250 255 Gly Glu Arg Val Ile Pro Leu Ser Asp Glu Leu Ala Arg Glu Ile Phe 260 265 270 Asp Tyr Ile Ser Asn Ser Arg Glu Lys Met Thr Lys Arg Lys Lys His 275 280 285 Asn Phe Leu Phe Val Ala His Cys Thr Gly Lys Asn Ala Gly Glu Pro 290 295 300 Leu Ser Ile Ser Ala Tyr Glu Lys Val Ile Ser Thr Leu Lys Arg Ala 305 310 315 320 Ser Pro Glu Leu Tyr Asn Leu Ser Gly His Arg Leu Arg His Ser Trp 325 330 335 Asn Tyr Met Tyr Ser Lys Gly Ile Glu Gly Ala Glu Leu Glu Tyr Asn 340 345 350 Arg Arg Lys Asp Leu Arg Asn Tyr Leu Met Gly Trp Ser Lys Glu Ser 355 360 365 Ile Met Cys Asp Arg Tyr Asn Tyr Lys Tyr Ile Ser Gln Gln Glu Lys 370 375 380 Asp Val Val Leu Lys Val Tyr Lys Ser Val Ser Lys Ile Ile Ser Gly 385 390 395 400 Val * <210> 1091 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22776..22982) <400> 1091 Met Asn Gln His Asn Thr Arg Leu Ile Arg Leu Pro Glu Val Leu His 1 5 10 15 Arg Thr Gly Tyr Gly Lys Ala Trp Ile Tyr His Leu Ile Asn Gln Asn 20 25 30 Arg Phe Pro Ser Pro Val Lys Ile Gly Ala Arg Ser Val Ala Phe Ile 35 40 45 Glu Ser Glu Val Asp Glu Trp Ile Gln Leu Thr Ile Glu Asn Ser Arg 50 55 60 Lys His Val Ala * 65 <210> 1092 <211> 284 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(23082..23933) <400> 1092 Met Lys Asn Trp Ser Val Glu His Thr Arg Glu Val Lys Lys Trp Leu 1 5 10 15 Asp Ile Asp Thr Tyr Arg Gly Phe Glu Glu Leu Pro Leu Ile His Leu 20 25 30 Tyr His Glu Leu Leu Ala Arg Thr Leu Phe Phe Lys Pro Tyr His Glu 35 40 45 Glu Phe Glu Ala Glu Ala Val Arg Leu Tyr Ile Asp Arg Ile Phe Thr 50 55 60 Gly Lys Pro Phe Leu Ile Thr Glu Lys His Leu Gly Tyr Leu Thr Arg 65 70 75 80 Glu Asp Thr Leu Tyr Gln Pro Pro His Phe Phe Leu Thr Thr Thr Glu 85 90 95 Arg Leu Ala Gln Leu Ser Ile Val Gly Leu Arg Asn Ser Leu Phe Phe 100 105 110 Trp Asp Gly Ser Asp Glu Tyr Ser Val Asn Arg Glu Phe Leu Asp Ser 115 120 125 Pro Val Ser Glu Val Leu Pro Lys Leu Phe Arg Asp Thr Val Met Val 130 135 140 Glu Ile Asp Leu Ala Asn Gly Thr Asp Glu Glu Ile Ala Glu Ser Leu 145 150 155 160 Lys Ala Ala Leu Pro Gln Trp Arg Lys Val Arg Gly Ile Glu Pro Asp 165 170 175 Val Thr Glu Ala Ile Arg Phe Gly Tyr Gly Thr Ile Lys Lys Ile Ile 180 185 190 Asn Tyr Arg Leu Leu Pro Met Ile Asp Ile Leu Val Trp Ser Lys Leu 195 200 205 Tyr Lys Val Arg Ile Ser Glu Asp Arg Leu Ser Arg Leu Leu Tyr Thr 210 215 220 Asp Asp Asp Asp Glu Ile Asn Thr Arg Leu Asn His Gln Ile Arg Asp 225 230 235 240 Thr Asp Lys Pro Leu Ala Leu Lys Ala Ala Ser Ile Pro Phe Ile Arg 245 250 255 Gln Phe Asn Leu Phe Ile Asn Lys Asn Ser His Leu Lys Lys Ile Arg 260 265 270 Val Ser Asp Val Met Lys Ile Ala Asp Ser Asp * 275 280 <210> 1093 <211> 23480 <212> DNA <213> Escherichia coli O157:H7 <400> 1093 taagttacac atcattagta ccttccttat tttttgactg ggacaaattt gggaccgatg 60 ggttcaggat cgagtctatt tgccgtgcgt gttcggtaag gtgattaggt gcaaggtgag 120 catatcgacg aaccatttcg atagactccc agcctcccat ttcctgtaac actgacaacg 180 ggactccggc ttgaaccagc caacttgccc aggtgtgtct caagtcgtga aatctgaaat 240 catcaatacc agcccgtctc agcgccgctt tccaggctgt gtttgcgtca taccgcatct 300 tccttactgt tggcgctttc gttccgtctg gtttggtaca gctttccttg tacacaaata 360 cccaacggtg atgattaccg atttgttttt tcaatacgcg acatgcagta tcattcagcg 420 caacgccaat tgcgcggttt gatttactct cttccgggtt tatccatgcc acccggcgct 480 gcatatctat ttgttgccat tcaaggttga tgatgttcga gcgtcttaag cctgttgcca 540 gtgcaaattc aacaacagac tttaatggct ccggacattc atcaatcagc ctttgtgctt 600 catggggctc cagccagcgg agccgtttat tctttggttg aggcacttta ataattggtg 660 ccttatcgag cattttccat tcacgctctg cggctcttag cagggccttt ataaatgaaa 720 gatgcgtagc cttcgttgca acggacgctg gttttggcgt gtattctgga acaggtttcc 780 ctttttttct gcatgcttct gccctgagtt tccagttttc ctcatgacgc cggttcgtca 840 ttttctgcat tgctgaataa atttttgatt cagtaatgtc tcttagttgc attcctgcga 900 aatgttgaag ccagaatccg atctgctttc cattgagcct gtttctctgc gcgacgttcg 960 cggcggcgtg tttgtgcatc catctggatt ctcctgttag ttagctttgg ttgtgtgtgg 1020 gagtcgtagt cctgaacgaa aacaccccgc aatggcacat tggctgctaa tccggattcg 1080 cacttccggc caatgcttcg tttcgtatca cacacaccaa agccttctgc tttgaatgct 1140 gcccttcttc agggcttaat ttttaagagc atcaccttca tggtggttag tgcgtcctgc 1200 tgatgtgctt agtatcaccg ctagtggtat ttgtgtcaac accgccagag ataatttatc 1260 accgcagatg gttatctgta tgttttttat atagatttat tttttgcagg gttgtgtggc 1320 ttgggaggtg atcgagagat cagaattgcg ttgtttagtg agttgcacct attaatttta 1380 aaataaatac aattggtgtt tttcgagttt ttcttaactc ttcatgcagc tccgttctca 1440 gaatatatga tttttcgagt ttgaaattct tgcgaccagg cgtcttattg ccaggctcag 1500 gaagtggaag gcgtgtttga atgtcgagtg gtggacagtc atagaagtaa attctataaa 1560 gctcaagcgg ttccctacgt tcttgtgatt gacgttttcc attaagatgg gaaagaacca 1620 ttgaccatat tactttcatt atgcattgcg cagtcagttc atgctcggcg aagtgtttac 1680 gatgcgtagc atgaacacgc tgcatgaaaa aacccgcatc aattaaaatt gctgctttct 1740 tcataagagt cccaaaaaaa tagcccagag ccgttatgca gatattaaca attgtctgcg 1800 aacggggctg ggcttggttt aattaatcta tgccaagttg actgtgccgt caacataaaa 1860 cttacttcct atcacccaaa cgtctcttca ggccactgac tagcgataac tttccccaca 1920 acggaacaac tctcattgca tgggatcatt gggtattgtg ggtttagtgg ctgtagaaac 1980 acctgaccgc tatccctgat cagtttcttg aaggtaaact catcaccacc aagtctggct 2040 atacagaaat cgcctggctc aacagcctgc tcagggtcaa ccagaattaa catcccgtca 2100 ggaaagctgg gcttggatcc tgttggtgcg gtcatggaat taccttcaac ctcaagccag 2160 aatgcagagc cactggcttt tttggttgtg cttacccatt tctccgcatc gcctttggta 2220 aaggttctaa gctcaggcga gaacatcccg gcctgaacat gagaaaaaac agggtactca 2280 tactcacttc taagtgacgg ctgcatacta accgcttcat acatctcgta gatttctctg 2340 gcgattgaag ggctaaattc ttcaacgcta acgttgagaa tttttgcaag caatgcggcg 2400 ttataagcat ttaatgcatt gatgccatta aataaagcac caacgcctga ctgccccatc 2460 cccatcttgt ctgcgacaga ttcctgggat aagccaagtt catttttctt tttttcataa 2520 atagctttaa ggcgacgtgc gtcctcaagc tgctcttgtg ttaatggttt cttttttgcg 2580 ctcatacgtt aaatctatca ccgcaaggga taaatatcta acaccgcgcg tgttgactac 2640 tttacctctg gcggtgataa tggttgcatg tactaaggag gttgtatgga acaacgcata 2700 accctgaaag attatgcaat gcgctttggg caaaccaaga cagctaaaga tctcggcgta 2760 tatcaaagcg cgatcaacaa ggccattcat gcaggccgaa agattttttt aactataaac 2820 gctgatggaa gcgtttatgc ggaagaggta aagcccttcc cgagtaacaa aaaaacaaca 2880 gcataaataa ccccgctctt acacattcca gccctgaaaa agggcatcca attaaaccac 2940 acctatggtg tatgcattta tttgcataca ttcaatcaat tgttatctaa ggaaatactt 3000 acatatggtt cgtgcaaaca aacgcaacga ggctctacga atcgagagtg cgttgcttaa 3060 caaaatcgca atgcttggaa ctgagaagac agcggaagct gtgggagttg ataagtcgca 3120 gatcagcagg tggaagagag actggattcc aaagttctca atgctgcttg ctgttcttga 3180 atggggggtc gttgacgacg acatggctcg attggcgcga caagttgctg cgattctcac 3240 caataaaaaa cgcccggcgg caaccgagcg ttctgaacaa atccagatgg agttctgagg 3300 tcattactgg atctatcaac aggagtcatt atgacaaata cagcaaaaat actcaacttc 3360 ggcagaggta actttgccgg acaggagcgt aatgtggcag atctcgatga tggttacgcc 3420 agactatcaa atatgctgct tgaggcttat tcgggcgcag atctgaccaa gcgacagttt 3480 aaagtgctgc ttgccattct gcgtaaaacc tatgggtgga ataaaccaat ggacagaatc 3540 accgattctc aacttagcga gattacaaag ttacctgtca aacggtgcaa tgaagccaag 3600 ttagaactcg tcagaatgaa tattatcaag cagcaaggcg gcatgtttgg accaaataaa 3660 aacatctcag aatggtgtat ccctcaaaac gagggaaaat cccctaaaac gagggataaa 3720 acatccctca aattggggga ttgctatccc tcaaattggg ggattgctat ccctcaaaac 3780 agggggacac aaaagacact attacaaaag aaaaaagaaa agattattcg tccgagaatt 3840 ctggcgaatc ctctgaccag ccagaaaacg atctttctgt ggttaaaccg gatgctgcaa 3900 ttcagagcgg cagcaagtgg ggaacagcag aagacctgac cgccgcagag tggatgtttg 3960 acatggtgaa gaccatcgcg ccatcagcca gaaaaccgaa ttttgctggg tgggctaacg 4020 atatccgcct gatgcgtgaa cgtgacggac gtaaccaccg cgatatgtgt gtgcttttcc 4080 gctgggcctg ccaggacaac ttctggtccg gtaacgtgct gagtccggcc aaactccgcg 4140 acaagtggac ccagctcgaa atcaaccgta acaagcaaca ggcaggcgtg acagccagca 4200 aaccaaaact cgacctgaca aacactgact ggatttacgg ggtggattta tgaaaaacat 4260 cgccgcacag atggttaact ttgaccgtga gcagatgcgt cggatcgcca acatcgataa 4320 ccaggacatg acgatatcgg tctgggtctt tcctgatact gatatttcag atgtatcgcg 4380 tgagttaatt gcggcaatta aacaggggta tctaacagta aaagccgccg gggtatgggc 4440 ggggggcatt gaaacacctt cggtggaaac tccatcggaa ggctctaaat tttttggttt 4500 tgatatggat aacgaattca tcagtggttt tgatgtaggg gcatggggag tattactctg 4560 atggcgaaaa atgactttaa agcgtttgca actgatcgaa atgccaatgt tatgtcgcag 4620 gaggaatggg aagcgttgcc tgcgcttata tccggattta cagcagggaa agcatccagt 4680 gcgcaagtca ataaggttat tcggcaggcc agctttattg ctgcagctct ggcccagttt 4740 gtaagtgata aaacgcaacg ggatgtgctt gataatggtg atctgcccgg ttttgttgaa 4800 ttgctgggat cggggtttgc tgttgaatac ctgagccgca agaatccgtt tggcgatatc 4860 aaatcggacg gcacggtgaa aacggctctt caaaaccttg gtttgggaga aggtgctcca 4920 gctattggcg ttccgttctt ctggccgtcc gctgcaatgc caaatactgt aatcgacagc 4980 tggtcctgta tggtgttttt gaagttcaac ggcgcgaaat tctctgccac tgattatcct 5040 gtgctggcga aagtgtttcc ttcgctggta ttacctgaag cccgcggtga tttcattcgt 5100 atctgggatg acgggcgagg tgcagacggt ggtcgcgaat tattaagctg gcaggcagct 5160 acaaactttt ctcagtttgc cgggaatata ggcgaaggtg cgggacacgc aattaacttt 5220 catgatggca tcgccggaaa tcagccagga ttttcacgat ttaatttcac cagtaactct 5280 gtgggtgatg gtgtgaattt tgttgcagtc agaccgcgaa atattgcatt taactttctg 5340 gtgagggcta aataatgaaa cctgtttttg atgaaaatgg gctggctaca gtgccgggcg 5400 atatgcgttg tttttattat gatgctgaaa catctgagta tacgggctgg tctgatgaat 5460 atattaatac tggcgtaagt atgcccgcct gttccactgg tattgaccct ggcgaaaaca 5520 ttccgggaag agtggcagta tttacaggta agggatggag ccatgaagaa gaccatcgca 5580 atgagactgt ttactcaatc gaaaatggcg cagctgttac agtggattat atcggtgcca 5640 tcaaagacgg ttatgtcacg atttcaccgt taacgccata cgataaatgg gatggtgaga 5700 aatgggtgac agacactgag gcacaacaca gtgccgcagt agacgcggca gaagcacagc 5760 gccaatcact gattgatgca gcaatggctt ccattagtct gattcagctg aagttacagg 5820 ccggacggaa actgactcag gcagaaacaa cccgacttaa cgccgtgctg gattacattg 5880 acgcggtgac ggcaacagat accagcaccg cgccggatgt catctggcct gaactgccgg 5940 aggcgtaggc cattcaatat ctggcgcacc ggaagtatcg accagctcca gtgcgtccag 6000 ataatccagc cacaaattat attgcgtcag ttcgtcacct ttcagacgac caatagccgc 6060 tttaccgggc cattgcttac tgttcatgta ttcgttggcc tggttaatta gtagctgtct 6120 ttctgattca gtaatttcaa taagctcttc atgcgtgggt ggaggaatat ctgcccacgc 6180 aggcagccca tcatctccgg caatacggat ttttccttgt ggcggttcag ccataaactc 6240 actgataata ttttgattta cttccttagc gtctgataaa tcccatccct ctgatttata 6300 tttatcaatc atatccacag ggaaaaaagc attatgcctt gcgctataaa catattcgtc 6360 catataaatc accctgaata aaattactca ccaacagccc accaactgta attcatcgat 6420 accgtgtcgc tggttgatga cgttctgtaa gcagaattaa agccggttaa cgttgggcct 6480 tctgcagtca tcacgaaccc tcgcccagcg cctaaaggcg caccgccatc accagaatga 6540 gtaagcatgg cgcagtccgc ttttttgggg aaagggatgc tgaatgtaat tctcattgtt 6600 tgcgtcgata atgtcggcgt aaccgcacca cgaccatatt gcaggatttt cccgttgggt 6660 aatttcatcc atccattacc actggcaaaa gaggccatgt ccggtatctg attttcccct 6720 gtccccacat cccgttttgc cgcttctccc aaaccaacgt ttatgaaaat gcagaaataa 6780 cgagcaaatg gcatcattcc tgcttttgtc agggagatct accatgctta ttggctatgt 6840 acgtgtgtca acaaatgacc agaacacaga tctacaacgt aatgcgctga actgtgcagg 6900 atgcgagctg atttttgaag acaagataag cggtacaaag tccgaaaggc cgggactgaa 6960 aaaactgctc aggacattat cggcaggtga cactctggtt gtctggaaac tggatcggct 7020 ggggcgcagt atgcggcatc tggtcattct ggttgaggag ttgcgcgaac gtggcgttaa 7080 ttttcgcagc ctgacggatg ctattgatac cagtacccca atggggcgct ttttctttca 7140 tgtgatgggg gccctggctg aaatggaacg agaactgatt gttgaacgaa caaaagctgg 7200 actggaagct gctcgcgcac agggacgaat tggtggacgt cgtcccaaac ttacaccaga 7260 acaatgggcg caggccggac gattaattgc agcaggaatt cctcgccaga aggtagcgat 7320 catctatgat gttggtgtat cgacactgta taagaagttt ccggccggag ataaatgaaa 7380 ccgtagcacg tcgtatgcaa gatcgtgctg cggtttatgc ttaccacttg aagattcaaa 7440 aattaggtga gtaacgaact ggagacatag ctcctttttt tcttaattca tctggtattt 7500 ttttcccaag ataaaggttt gctatttcag gtggggcttc tcgaccttca aaaccatagc 7560 gagagctttg tgttgcctca aagtcagggt cttcgtccca gtatttcatc gtaggaaaat 7620 gttcacgcgt tgattttagc catttatcag caatgaaaac tcctcgaacg atccccctta 7680 cagtagcaag aatgacttct gctttactgg cgcgcgagac attaatgcgc cagctaaatc 7740 gaaccgcatc ataaagctct gaatcttttg cacttctgtt aacggaaatc attaatgctt 7800 tatgatgaaa tgttatggtt tcgggttgat atgttgctat caactctttg acatgcgcgg 7860 cgccgaattc attgctgcca gcaccattca tgatattcgt taacccaggg taggcatcaa 7920 taagtgctgc ttcaacttcg tacgccgtct tttcatcagt cattccatgt cgatggatga 7980 catggataac ttcaagtccc gctaatctta tttctctgat ttgctttagc ttgttgctca 8040 gtaagtcgtc atcatcagcc gctgccactt caccgcgcat atgggcaaat acgcggttac 8100 ctttgccttt ccctacatag aaggtgcttc cgtccctagg atcaatcaat cggtatacat 8160 accagccaag gtgttcaatt actccagaag gaaactcagt aatatccatt ttgcaatatc 8220 tgtgaattat ttgtgagacg tatattaatg aacattgcaa gggctcacaa ctagtagtgt 8280 tgagaaagcc atcgggaaaa tgaggctaac cctttgaatt tacatagcgc aaaaagatac 8340 ctttcctcat aatgtgagct aattttatgt ttcgtttgat gatcgggtcg gtctcgaaaa 8400 ccggagtagg ggcaactcta ccgggggttc aaatccccct ctctccgcca ctttatcaat 8460 gacttatctc ccgacttccc gtcttgcttt tcctaaacag aacaatcgta gaatattctt 8520 gaagggttag atcgtcactg ttttctgttc gatactgtga cattcagcac ttgattcgct 8580 atggatctga caggaaggtt ttgagcgaaa atctgcagtt attcagtcgt tttcttatcg 8640 gtcaccatta ttcttttaga cattgatcct acaaagctgc cgcaaagttg gtggtgggaa 8700 ctgaagttgc gtagagaagg ggtcaatacc cggaggcaaa catgggctgg caaaagtgta 8760 gcggtattag gcgcagctat ttagcctagt tatgttttat gaaaacttga tatcatataa 8820 gtgtcttact tattggctgt aaataagttt ttcctaagga attgtttctt gagtatcatt 8880 tgtaactgta acggaattta taatcctttg ctttattgtt acggtatttt ttatcacacc 8940 ctatttttag tggtttttta tactgaagtt tggcaaagtg aactttatat acatatactt 9000 catcctggtt tcagttaaat tggggggatg atatggcaac tacatgttca gttatattga 9060 ttttggagtc ctttgatgtt tatttcggaa aagagagtgt gtttctggag agaggttcat 9120 ctgtacttgt cgactctagc tctagagatt ttttcctgac atatcctgaa agagtgatag 9180 tggcggattt tggcgctgag tttattagtc gctatttgaa agctaataac ttaagggata 9240 tttctgattg tagggaatat ccatcttatt taaaaataaa ctttgctgac ttcagtttaa 9300 ttaaaggatt aattagttgg gctaatcact gtgctgaata catagaaatt tttgatgagt 9360 ctattgcttt tacatgtctc tctgcatttt cttctgaaaa acaatttgga gtatttctgt 9420 ttggatgttt gaaaagcaca ggggctaaag ttaaaacgat tattcatacg gatttatctg 9480 caccatggcg tcttaaggat atatcatcaa gattatatct cagcgaaagt ttactaaaga 9540 ggaaattgaa agaagagggg gtatcattca gtaagatcat acttgatgag aggatgcaaa 9600 tggctgaata tttactcagc actcgttgtt atcctattag taaagtagct aaggtctgtg 9660 gttatgccag tgtctcatac tttacttatg tatttagacg ttattttggt gtttctccaa 9720 gtcaatactc tcagaggagt tcagaaagta aaattcttac tcaccaggga atctgatcat 9780 tgttcttgcc cccttatttc cagacagggg gggtatctta agttaacgtt acccgctgac 9840 gtcgatattc tcgcggagag cgataaccca acgcactgtg cggatggttt tcattgtaat 9900 gttcgatcgc cactgcaaga ttatgcaatg ccgttcttac attcggtttc ggcatgaacg 9960 cgatgtagtc ttccttcatc gttttcacga acctttctgc aattccatta ctctgaggac 1002 0 tgctgattgc cgttgtgcag ggctccagat tcaactctct ggcgaactgc cgtgtttcat 1008 0 gcgctctata cgctgaaccg ttatctgtca gccactggat ggactgttcc ggtactttat 1014 0 cgccaaagcg tttttctatc gctcctaaca tgacatcctg cactgtcgct ttatcgtaac 1020 0 ctcccgtgct tgcggcccag tctatggctt cacgatcgca acagtccagg gcgattcatc 1026 0 tgggccaatc cttgctcata acaggcattc acttcagtca tggcagaaag gtatgcatgc 1032 0 tggagaagtc gtgaaagaaa agaagactgc tgcgccgttt gtcgtcacgt ttatcttcat 1038 0 tggctatgca agtcgtaata caaggtggga caaaactgag acacataagg cctcgcaatg 1044 0 gcttgcaagg ctttacatgt tttgatgtgg tgggacgtgt gagcgcagtg ttgatggggt 1050 0 aatgctttga attagaagcg gattcttata attcgtaatg cgaaggtcgt aggttcgact 1056 0 cctattatcg gcaccatctc aacttcctca aacgtccgta ttagtccata aaatctctga 1062 0 tttataacat tttttattct tttaagtcca tagtagtccg taaccatcca gtagaatccg 1068 0 gtactgaatg tgtataggat tgtgtatatg ttcctgttcg gtctggattc ctatacacat 1074 0 gcctttaaac gatatgcaga ttcgccgcgc taagcctgaa gctaaagcct atacatttgg 1080 0 agatgggcta gggttgtcat tacttataga acctaatgga agcaagagtt ggcggttccg 1086 0 ctatcgctat gccggcaaac ccaaaatgat ctcgcttggt gtttacccaa cgatcaccct 1092 0 tgccgatgct cgttcccgtc gtgatgaagc tcgaaaactt gtggcagaag gaaagaaccc 1098 0 tagtgaggtt cgaaaagagc aaaagctagc tatgcaaaca gagtcagaga acgccttcga 1104 0 aaagatagcc agagagtggc atcaacttaa atctgctaaa tggtcggcgg gatatgcatc 1110 0 agacatcatg gaagcgttta agaacgacat ttttccttat gtcggaacaa ggcctgtggg 1116 0 agagattaaa ccgctagagc tgctgaacgt tctgcgtaaa attgagaaac gtggtgcgtt 1122 0 ggagaaaatg cgcaaagtgc ggcagcgttg ctccgaagtg tttcgctacg caattgcaac 1128 0 gggtagggcg gagtacaatc ctgcggctga tctctccagc gctctcgaag tacaccaatc 1134 0 caatcatttc ccattcctaa aagctgatga gatacctgat tttctacgtg ccttagaggg 1140 0 ttactccggg agtaagcttg tccagatagc cacgaaatta ctgatgatta cgggtgtgag 1146 0 aaccatcgaa ttacgcgcgg cattatggca agaatttgat ctggataacg ctatttggga 1152 0 aattcctgct gaaaggatga aaatgcgtag gccacatctt gtgcccttat catctcaagc 1158 0 ggtagattta ctcaatgaac tcaagatcat gacagggaac tatcgttatg tttttccagg 1164 0 gcggaacgat ccgaataggc caatgagcga agcgagtata aatcaagcca ttaagcgtat 1170 0 tgggtatgga ggaaaagtca ctggacatgg ttttcgtcat accctttcta caatcctgca 1176 0 tgagcaaggt tttgagagtg cttggattga aatccagttg gctcatgtag ataaaaattc 1182 0 tattaggggg acttataacc atgctcaata ttttagtgga aggaagtcta tgatggactg 1188 0 gtacagtaat ttgatatttg aaagactaaa aaggagttaa tttgtgtctc aaccactttc 1194 0 ggaaatattg acatgggatg atgaacaatg ggaggtattt gtccatgatt ggcttattgt 1200 0 ctgtaaatca gatgattacc cgtggagcga acgtttggga ggagctggag ataaaggtag 1206 0 agacgttgtt ggatataaat cggatcctaa cgtagaaggt tattcttggg ataattatca 1212 0 atgcaaactg tacaaaaaaa gtttagggtt ctctgatgtt gtagttgagt ttggaaaact 1218 0 tatctatttt actctgaatg gtgattatcc catccctcag aagtactttt ttgtggcacc 1224 0 ctatgattta tctactacat tttctaattt attgaaaaat aaaaacgagc ttaaaaaagc 1230 0 agtccttgat tcatgggatt cagcaatttc aaaaaaataa ctaaaaagat tgatattcca 1236 0 ttagatgatg aaataaaaaa atatattgag gattttgatt ttagtatttt ttactctcta 1242 0 cccttatcat tgattttaaa tgatattgca aatacacacc tttattttaa gtactttaac 1248 0 gagctgtatg tcgtgagaat ccctccaaat gaaattccaa catacaattc aaaaaaagag 1254 0 tctgtatatg ttaatgcact gcttcaagcc tattcagagc atggaaataa aacttatagt 1260 0 tctttcttag agcttgatga tccatacaga cgacacttta ataatagtag aaatgatttt 1266 0 tattttgcat cttcgcttga ggtttttgtc cgcgaagtat ttaaagatga tgtattcaaa 1272 0 gcattgaaat gttacatttc atcttcaatt gaacccgtct tttatgaaga ccataattat 1278 0 gcatttatta ggtgtaatgc agtcttgaag caggctgttc tgacaccaat tgcacattca 1284 0 gtactatcaa aaatatgtga agcaaatgat aaaaaaggaa tatgccatca tttggttaat 1290 0 gatggtgaag taatttggac ggtgagataa tggttagaat ttataattca agtttagaag 1296 0 tggcatgtcg aatggcgaaa gtgctcgtcg ctatttatcc ttcttcatta agccttgaac 1302 0 ggcttatttg ttttgatttt attttagtaa atcttaagga ttttttacct gaagagatta 1308 0 gtcttcatcc tccaataccc cgtagagatg ctcagttagc cctaaaacga gagattgttt 1314 0 tagaatcatt ggctttgttg caaggctatg aactagcctc aaaaatttat acacatcgtg 1320 0 gttttgtata taaagcttct gaaaaaacat atgcatttac aaattctcta cataatgaat 1326 0 atgttgcgca gatggagcat aatataaatt tggtggttaa gttatatagt gatattcctg 1332 0 atgagcagtt gcaatcaatt ataaaaaata aaattggcaa atatgatatg gaatttaatt 1338 0 atgaatgaca atttttttac gttcagaaaa ataaaggtaa ccggattcaa taaattagat 1344 0 gctataattg aatttggttc taaattgact attttatatg gtggttctga ctctggaaaa 1350 0 acatacatat attatttgat tcgatattta ttagggagtg aaaaactaaa aaataaagat 1356 0 atcgatcatg ctcaaggtta tgatttagcc tatctggaat ttaattttca aggtagggta 1362 0 atgacaattg agaggtctct tcaggatagc gcccattaca gattatatga ttcgagcatt 1368 0 gaaaatgtta gtgaagctaa tctgttgatg gttttttcca aaagtgcttc gtctaaaaag 1374 0 agtttttcat catactttta tggtaggttg aatttcaaag aggctaaagt aagaacaaac 1380 0 ttaagtaata ctcttcataa atttaatctt aataatgttt ttgaattttt ttgtattgat 1386 0 gaattaagag tgttaactga gaagtcgtta attctttctg atattcctag cgaggagaca 1392 0 aaaagaaagt ctgaatttaa attcctttta actcagagag atgatactaa ctccttagca 1398 0 gaaaaaccaa ataaaaaagc aagatatttt taaaaaaatc aaattgcaaa tatttatgag 1404 0 gaattgaaag cgcaattaat ttatcctgaa tatgatcaag tcattgtttc aagagaactt 1410 0 gagaaagtag agcaagatat tgaatcatcg aaagatatat tgaaaggtat tgttgatgca 1416 0 cttgatgata agaagcaatt attaaaagag ttaagtgatg aattatattc aatcagtgac 1422 0 agggaaaaat acttatcatt actcattgaa agatttagtc ttcttaaaga ccaatacttt 1428 0 atagatctac aaagaataga tgttgtatca caggcgaatt tctatttaaa taattttgca 1434 0 gatatttatt gtgagttctg taatacaccg caaaaaaaag aaaatgaaat atcatatgat 1440 0 gattgttttt tgtcgtgtaa tgcagaaaaa ttgaaaatca aaagccagct gaaaggatta 1446 0 attgaatcaa tcggatctaa tgttcgcgaa catgaattaa ttatgttaag aaaaaatgat 1452 0 gttaatgaaa tttatcaatc agaaaaaagt gattttaaga cgttagaaga taaaaatata 1458 0 aaacaataca ttcatctctt gaatcacttt atgaatataa agacaatctt ttaatggatc 1464 0 acacaaaaca tagcattcta tcttcattac aagataaaga agatgatgtt gacgaactta 1470 0 aatactccgc cgaggacttt gactccttaa cagtagctga tttgtatgat atagaaatag 1476 0 cgatgcaaga ctttttgaat gatataaatt ttgaaaattc taaagataac aaagtgcgat 1482 0 ttgacgaaga tacatatgac tttaatatca atgggaaacg ccgaggaatg tttggtaaag 1488 0 gtacccgtgc agtaatgcat gctatattta ccatttgctt tgcggaattt ttatcaagaa 1494 0 aagggaatcc attcattgga tttgttgtgc ttgatagtcc attagtgacg cactttgata 1500 0 aagatagagg gggttctcta tcggatgtta atagcgtcag tctcagtgat tcattttatc 1506 0 acgcattaat caaaagggac tataatttcc agattgtaat tcttgagaat aaaggtccga 1512 0 cgttccaaat aaaaattaat gatgcaaata aaatccataa cttaaataag aatggaagct 1518 0 ctggttttta tcctgtttaa tacattaaaa atataactgc taattggggt gctcgaaatt 1524 0 atatttcgtt tcgagcgctc agttcatttc taaataattt gcaaaattat tttgggtact 1530 0 ttcgcctcta cacttccttc gggtggttcc acaataatgg atctcaccgg cgtttgatat 1536 0 tttataatct aaccccttag cgcgcgcagc cccccacgcc tgctcgcttc gcttaacaga 1542 0 ctggttttca tgcattccgc aaatcgtctc agaagccacc acacaagggc tttcgcgtca 1548 0 aaaatggtgc atgagaatca tgcgttttca tgcgctatag acatgcactc atgcgctctc 1554 0 aggccagcca gggaaaaggc gtaaaaaatc ccagtactgg accgggatta cgtgggcttt 1560 0 ttttgctaat cagacaggaa tttgctgacg gcttgacagc tttgacgcgg agccatagcg 1566 0 attgagagtt tgctgttgtt tttccggcat ttgtgctttc tctgattcct gttcattgcg 1572 0 ccggggcttc atgattatcg tatccacact ttccagtgcg gtaaatgtgt aggaacattc 1578 0 aagattctgg cactgatacc atgagcgttt aaccgatggt gcttcatagg cggaggttct 1584 0 ggcgtgtgcc gtcgtaccgc attcgggaca tttaagtgcc attaatatta ctcctgcatg 1590 0 ccgttaatgt aatccagacg ttgctgaaag cgcagttgtt gtgcaggggt gtaagagctc 1596 0 tggcaatcac gaaccatcat ggggtcaggc atcacaccgg attcatccag aatcatacga 1602 0 taatccccgg caatttcagg cggtgttatt gccagctggc gaaccagagc attgcgtaat 1608 0 atacgggacg caacgtcaac ccctccgcgc cccttcagga acggagccag tgcagatgtc 1614 0 agggctgctc cattcgcctg cataaaattg ctgagagcgt cttctgtgca ggcctccatc 1620 0 agttgatgct gcgagtaaat gcattcgcgc gcagcacagt taatttgcca tttcagcaca 1626 0 tccagatgtt cccgctgtaa ttcgagctgt cgagcataat ctgctggttt ttccatggca 1632 0 gtgaggagtg attctatctg ttgttcaacg gcttttcggc tctcactatg tccagcccac 1638 0 agaatacggg catttctaaa actgataagc gcttggtctg gagtgactcg ggccatcata 1644 0 ctgctttctc cttctcagca cgttcctgac gaaccttcat tttatgcata gctgctggag 1650 0 agagtttatt actgaaatcc agacgggccg cataatccgg ggcaactccc gccagtttaa 1656 0 acacggggtc ctgttcgggc atcgcatcgt tagtcagagc cggtctggtg atatgtttat 1662 0 gaataaaatc tttcagcagt gtgtccgggt cattaactga atgcaccaca ccgacaactg 1668 0 cgctggcttc cctgcccatt gttgatttga gcaggcttag tgtctggatt agtgcttttc 1674 0 catgcgactg cataaaatct tcccagattt gttttgcgcg aatacccaca agggtgtcgt 1680 0 gcgcgtggat atactttccg gctaattccg cagcctcctg cggcaaaagt gcattttcgc 1686 0 tttcctgagc cgccagcagc tcatcaaaat cctcaagcgt ttctcgtccc agcgcaattt 1692 0 ccgtgcgcag ttttttcatt tcctttgaga ctacgccctg actttcacga aatagcgtgc 1698 0 gccactcctc attcagggcg ttcgtcgtgg cttccatttc agcgcggcgc tggcggattg 1704 0 tcgcaatatt atccgctgcc gctttttgct gacgacgtgc ttcaagccat gcagatttgg 1710 0 tggcattcac tttctcaagc gcctgttgcg tcgaaacagg gatagaaatt tcaacgatcg 1716 0 ggttattgtt ctgttctggg attgtcatgt cagcacctag tggtttgtcg tggtgtcaat 1722 0 tgtgctgtga tgcatacaaa gctgccattg aacgccattg tgcgagcgac aagacaaaga 1728 0 ctgaaccgcc ccggacctct tttggctagc cagaaaaggc ctcgtttaac taaggctgtt 1734 0 tcagacttac cttaactatt cactactatt cacttaggta aaaaaaatag gtaatacaga 1740 0 aggttataag gtgaagggtt ggcatggcag tattcatcga ctgttcataa ctgttcacat 1746 0 gggaataaaa ttatttatgg tattttttca taatgggtgg tttttttatt cctcgtagct 1752 0 atttgttttt tgctcctcac cactattcac ccttattcag gagtattcaa caggcacata 1758 0 aatagactgc atgtttttgc cggggaataa cattttcgcc tctggccatg gtgttgcatt 1764 0 tcatactgat ttttataaaa ctagatctgt ccggttcttt atggattcat tcggatatat 1770 0 tttacgattt aaggtgatgt tatttaatat caaggttttt atgcaggccc aatgtttata 1776 0 agttggatgc gattcaaaaa tatgcccgga aattggggcc tgcaatgcaa ggcctcgtgt 1782 0 agaagttgta ctgccttgct gtattggcgg tggggttagc actatcaggt gcaatgaccc 1788 0 ataggatagt aaaccctggg tgaatggtag ttcctattaa tgctcctgta tttatagtcc 1794 0 gcaggcatgg tatttattat gtcattttat atggtttaat cgggctttaa attccataaa 1800 0 atcaatatgt gacgctaaat aaaaaatgcg tgcgcaggtg gtttatatac acataataag 1806 0 gaactacctg aacccggata aattcatccg gactgttgtg gaaattaaag agggtagata 1812 0 aatgcgtaat atttctgtgt ctgcgccagc tcctgctgcg ccattatttc ctgtatcgaa 1818 0 ccatcatgag cgatttttac gcctgcctga ggtgatgcac ttatgcgggt tgtcccgttc 1824 0 gaccgtttac gacctgatca gccgcgatgc gtttccgaag cagatcccgc ttggcggtaa 1830 0 aaatgtcgcc tgggcacagt ctgaggtcag cgcatggatg gcggaccgca tcagcgcccg 1836 0 tgggcgggga tgtgatgcat gatgatacct gcatacatta aataccttta ttctggcttg 1842 0 cttactgtcg tcatttccag gtatagtttt tccgctgtcg caaaatcggc agccggaatt 1848 0 ggcgttccgt ataacttatt ggcgacaatt gacgcccctt gcgtcttttt ttacgtcgta 1854 0 gctcaggcac aaccattttc agggctgtgg tgtttatgct tacaccatgg ttctatcgag 1860 0 ataatggtag tccgggcggg gcagccttcg ggctggccgg tttccaataa ggccggttac 1866 0 gccaaccccg ttcgggctgc caccagtgaa attggcgttt ccggtggtag caataaccgc 1872 0 tacttattgg aggctgccat catggctaca atcctcaccc cgtcacaccc gcaatatgtc 1878 0 tttgtgtttg ccgcaatccg ccgtgctgac actcaccccc gcatctgtat gcttcgcact 1884 0 gtctcctgcg atgagcgttc cgcgcgccgt ttgctagtcc gagattatgt actctccctt 1890 0 tctgcacggc tgcctgccgg ggaggtgacg ctatgaacca gtttgagatt tcctacgacg 1896 0 atgttgtaag gctgaaacat ttacgcaatg tgggtgagta tgtaactggc atggcagccc 1902 0 tgcaggactg ttatgaaaag ccagcaggtg cccaatgcga acaactggtt tccctcattt 1908 0 atctgatgac agagcaactg gatggagtgg tgcaacgctg ccatgacgac ctgatgaatg 1914 0 cggaggtggc ctgatgatat gctgtgaatc tcttctggca cttcgtgccg ctctgtatcg 1920 0 ccgtgccgtt gcctgtgcct ggctggctct aagcaatcat caggaacgtt attccggcct 1926 0 gacgctcgct gaacttgaag atgccatagc ccgcgagctg gaagggttct atctgcgcca 1932 0 gcatgggcag caaagagggc tggaaattgc ctgcgcgttg ctttcggatc tgatggagtc 1938 0 ggggccgctt aaagcctgtc cggttctctc actgctcgga atgacggtca tggatgaact 1944 0 ttgttcccgt cacctcaaca aaccagcgct gcactaagga gggccgcaca atgtcaggaa 1950 0 tgaaagttag ccaggctgag aaagcagctc ggggtcactg gtcaagaatt ttacctgcgc 1956 0 tgggcgtaaa tgtactgaaa aatcggcacc agccctgccc ggtctgtgcc gggaaagacc 1962 0 gctttcgatt tgatgaccag gaagggcggg gaacgtggtt ctgtaaccag tgcggggcag 1968 0 gtgatggcct ggcgcttgta agtaaagtac tggatgtagg cattagtgaa gcggcagaca 1974 0 gaataaacgg cattatcgga aacctgctgc cagtatctca gggaatgctt gaatctggtt 1980 0 ctcctgaaaa agaggacggg agaaaagctg cagcagtgct ggctgcccgt ttgtttgata 1986 0 agtcccgcca gaccactggc aatgcctatc tgacgagtaa agggtttcct gcactgcctt 1992 0 gccgggaatt aaccgctatg cataaagtcg gtggtgtggc atttcgcgcg ggagatcttg 1998 0 tcgttccatt gtatgcagat ggagagctgg taaatctgca gttaatcaac gctaatgggg 2004 0 gcaaatgctt ccttaaaggc ggtcaggtta agaatgcctt ttacctggtt gaaggtactg 2010 0 ccaaagcagc caaacggctc tggatagcgg aaggatatgc caccgcactt actatcaact 2016 0 atctgactgg cgatgctgtc atggtggcct tttcgtccgt caatttcctt tccctggcga 2022 0 gcattgcctg cagtgagtac ccaacgcacc agataattat tgctgctgac cgcgatctca 2028 0 acggtgcggg gcaaacaagg ggcgcagctg ttaccggggc ctgcaattgc acaatggcgc 2034 0 tcccgcctgt gtttggtgac tggaacgatg cattcacgca aaacggcgaa gaagccaccc 2040 0 ggcatgcaat tcatgaagta ataaaaccag ctgttgccag ccccttcgac acaatgagcg 2046 0 aagctgaatt taccgcgctg agcgtcagcg aaaaagcgca gagggtagtg gatcactata 2052 0 aaaattcact ggcagtagac ccgaacgggc agctcctttc acgctatgag gcgggggcct 2058 0 ggaaagttat ctattacgcc gattttgccc gtgatgtcgc tgcgctgttt cagcgcctcg 2064 0 acgcaccttt ttcatccgcg aaaattgcgt ctctcgtgga aaccctcaaa ctgatcgttc 2070 0 cgcaacagca gaatccggcg cggcaactta tcggatttcg caacggtgtg ctcgataccc 2076 0 ggacaggatt gttcagcccg cacgataaga agcactggtt acgtacgctg tgcgaggtgg 2082 0 attacacgca gcccgttgac ggtgagtcac tggaaaccca tgccccggca ttctggcgct 2088 0 ggctggatcg tgccgcaggt tttaatcctg aaaaacggga cattattctg gctgcattgt 2094 0 ttatggtgct ggctaaccgt tatgactggc agctgtttct ggaggtcact ggccctggcg 2100 0 gaagtggaaa gagtattctt gctgaaatag caaccatgct ggcgggtgaa gataacgcga 2106 0 cctcggcaac cattgaaatg cttgagtcgc caagagaacg agctgcgtta ataggttttt 2112 0 cactgattcg acttcccgac caggaaaagt ggagcggtga cggggccgga ctaaaagcca 2118 0 tcactggcgg cgatgcggta tccgttgatc ccaaatatca gaacgcctat tcaacccaca 2124 0 tcccggcggt catcctggct gtgaacaata atccgatgcg cttcactgat cgtagtggtg 2130 0 gagtttcacg ccgaagggtg atcctgcatt tccccgacca gatagccccg gaggaacgcg 2136 0 atacccagct caaagagaaa attgccagtg agctagcggt gattgttcgc cagcttatgc 2142 0 agcgtttcag cgacccaatg agtgccagga cattgcttca gtcacagcag aactccgatg 2148 0 aagcgctcac catcaaacgt gatgctgatt cagcttttga tttttgcggc taccttgagg 2154 0 tcctacctga caccacgggc atgtttatgg ggaacgctaa tattgttcca cgtcagcctc 2160 0 gaacttacct ctaccatgcc tatctggtct acatggaggc taacggctat aaaaatacgc 2166 0 tcagtctgac catgtttggc aaggggctac cgttaatgct caaggaatat gggctgcagt 2172 0 atgagaaacg acggaccaat caaggaatgc agactaatct ggccctaaga gaggaaagca 2178 0 atgctgactg gttgccaaaa tgcgatgagt ttgcagcgaa ataactgacc taagaccggc 2184 0 tgtgccggtc ttaaatccgc tacaggaaat tatctcaaaa tatatatcga taaaatttaa 2190 0 aagttatatg ctaaggcgtc agcggaaaat gcatctaatt cattgttaga tgatgtttat 2196 0 ttttgaattg atttaaacat cccatcgagt tgtaatttat ttatgtcggt tttctttatg 2202 0 gctttaatta agttttcaat aacttccaaa gaaaaaatta catctttctt ttcaattcta 2208 0 acccccccgt ggtggctgca agcattaagg atgtcctttg taatttcaac atcatttttc 2214 0 attaatggtt catagtccag agcctcaata acagaaacta aactacctag catttgctct 2220 0 tggtattgaa cgttgtttaa atgcattata cgaatattaa caagcatgag aatatattct 2226 0 aaatatctcc tggcagtatt tcctttctct tgtaaagaat cacgatcata ttcctcaata 2232 0 ctcatgactt cattatgtaa agaggctatt ttgtgctctg ctaatgaaat atttatcgca 2238 0 tccatgaggt ttcgtgagaa gcctgtagat gtaacatgac catttgcggg ccttgttaaa 2244 0 atacatgtag tatagcaatt tatatttggg gtctggattg tctcatttac tcttttaacc 2250 0 gttctataaa cgtctaccat ataagaacct gagttttcaa atgaacatga agagcatttt 2256 0 gtattatata ttctatttag agataactga ttgtgatagt atccctttaa gaaagcatat 2262 0 atagtgtcat taaactcgac aaacacaacg gactcaatat atatatggaa tttatcattg 2268 0 gggtgccact ctaattcaag tcttcttgta gagtcatcaa aggaaaagtt tgaaataaaa 2274 0 tcccagttac ctaaatctat aaaatcaacg atatttctac ctgcaccatg gatattttta 2280 0 tttattaaag ttgtgattga gttttttata atgtcccaat catgaatttc atgatcgaat 2286 0 ttattattga tggtttcttt tatttgattg gaaaagtttg aataactagt cacttgttag 2292 0 cctcaaaatt aataatgagt attaaaattt aattgatatt gtctataaaa tgtagcgatg 2298 0 caattttatt gcaacgaaat gatttttaca acataccatt atcgctaaac aaaatcgcac 2304 0 ccatcaaatc aacttacgtt acaatcacta caaagcgatt gcatttaaat tcaaaacagt 2310 0 tttctgttgg gcgcattttt tgttgtactg gactaaagag aaaaaatggg gtaaggaaca 2316 0 aataccttcc gtgctcaaaa attaggtttt tatgcactta ttaatcagtc aaggtgaaca 2322 0 gtaaagtgtt cacttcttat caatcgttaa tttcatatct ttttgaatat taatgaaaaa 2328 0 aaacacaatg agtagtatga acagttttcc cccaaaaaaa gttttttctg ccttgagaat 2334 0 gcgcggaaag cgaacgcctt caccaatgtg tataggggtg tgtgtagttt aaatcttcta 2340 0 ttttaattta tgtattaaaa tcattgtgtt ggtggcgatt attggttcct attatcgcac 2346 0 catttaaatc aagtagttac 2348 0 <210> 1094 <211> 325 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5..979) <400> 1094 Met His Lys His Ala Ala Ala Asn Val Ala Gln Arg Asn Arg Leu Asn 1 5 10 15 Gly Lys Gln Ile Gly Phe Trp Leu Gln His Phe Ala Gly Met Gln Leu 20 25 30 Arg Asp Ile Thr Glu Ser Lys Ile Tyr Ser Ala Met Gln Lys Met Thr 35 40 45 Asn Arg Arg His Glu Glu Asn Trp Lys Leu Arg Ala Glu Ala Cys Arg 50 55 60 Lys Lys Gly Lys Pro Val Pro Glu Tyr Thr Pro Lys Pro Ala Ser Val 65 70 75 80 Ala Thr Lys Ala Thr His Leu Ser Phe Ile Lys Ala Leu Leu Arg Ala 85 90 95 Ala Glu Arg Glu Trp Lys Met Leu Asp Lys Ala Pro Ile Ile Lys Val 100 105 110 Pro Gln Pro Lys Asn Lys Arg Leu Arg Trp Leu Glu Pro His Glu Ala 115 120 125 Gln Arg Leu Ile Asp Glu Cys Pro Glu Pro Leu Lys Ser Val Val Glu 130 135 140 Phe Ala Leu Ala Thr Gly Leu Arg Arg Ser Asn Ile Ile Asn Leu Glu 145 150 155 160 Trp Gln Gln Ile Asp Met Gln Arg Arg Val Ala Trp Ile Asn Pro Glu 165 170 175 Glu Ser Lys Ser Asn Arg Ala Ile Gly Val Ala Leu Asn Asp Thr Ala 180 185 190 Cys Arg Val Leu Lys Lys Gln Ile Gly Asn His His Arg Trp Val Phe 195 200 205 Val Tyr Lys Glu Ser Cys Thr Lys Pro Asp Gly Thr Lys Ala Pro Thr 210 215 220 Val Arg Lys Met Arg Tyr Asp Ala Asn Thr Ala Trp Lys Ala Ala Leu 225 230 235 240 Arg Arg Ala Gly Ile Asp Asp Phe Arg Phe His Asp Leu Arg His Thr 245 250 255 Trp Ala Ser Trp Leu Val Gln Ala Gly Val Pro Leu Ser Val Leu Gln 260 265 270 Glu Met Gly Gly Trp Glu Ser Ile Glu Met Val Arg Arg Tyr Ala His 275 280 285 Leu Ala Pro Asn His Leu Thr Glu His Ala Arg Gln Ile Asp Ser Ile 290 295 300 Leu Asn Pro Ser Val Pro Asn Leu Ser Gln Ser Lys Asn Lys Glu Gly 305 310 315 320 Thr Asn Asp Val * <210> 1095 <211> 82 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(870..1115) <400> 1095 Val Cys Asp Thr Lys Arg Ser Ile Gly Arg Lys Cys Glu Ser Gly Leu 1 5 10 15 Ala Ala Asn Val Pro Leu Arg Gly Val Phe Val Gln Asp Tyr Asp Ser 20 25 30 His Thr Gln Pro Lys Leu Thr Asn Arg Arg Ile Gln Met Asp Ala Gln 35 40 45 Thr Arg Arg Arg Glu Arg Arg Ala Glu Lys Gln Ala Gln Trp Lys Ala 50 55 60 Asp Arg Ile Leu Ala Ser Thr Phe Arg Arg Asn Ala Thr Lys Arg His 65 70 75 80 Tyr * <210> 1096 <211> 130 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1355..1744) <400> 1096 Met Lys Lys Ala Ala Ile Leu Ile Asp Ala Gly Phe Phe Met Gln Arg 1 5 10 15 Val His Ala Thr His Arg Lys His Phe Ala Glu His Glu Leu Thr Ala 20 25 30 Gln Cys Ile Met Lys Val Ile Trp Ser Met Val Leu Ser His Leu Asn 35 40 45 Gly Lys Arg Gln Ser Gln Glu Arg Arg Glu Pro Leu Glu Leu Tyr Arg 50 55 60 Ile Tyr Phe Tyr Asp Cys Pro Pro Leu Asp Ile Gln Thr Arg Leu Pro 65 70 75 80 Leu Pro Glu Pro Gly Asn Lys Thr Pro Gly Arg Lys Asn Phe Lys Leu 85 90 95 Glu Lys Ser Tyr Ile Leu Arg Thr Glu Leu His Glu Glu Leu Arg Lys 100 105 110 Thr Arg Lys Thr Pro Ile Val Phe Ile Leu Lys Leu Ile Gly Ala Thr 115 120 125 His * <210> 1097 <211> 238 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1872..2585) <400> 1097 Met Ser Ala Lys Lys Lys Pro Leu Thr Gln Glu Gln Leu Glu Asp Ala 1 5 10 15 Arg Arg Leu Lys Ala Ile Tyr Glu Lys Lys Lys Asn Glu Leu Gly Leu 20 25 30 Ser Gln Glu Ser Val Ala Asp Lys Met Gly Met Gly Gln Ser Gly Val 35 40 45 Gly Ala Leu Phe Asn Gly Ile Asn Ala Leu Asn Ala Tyr Asn Ala Ala 50 55 60 Leu Leu Ala Lys Ile Leu Asn Val Ser Val Glu Glu Phe Ser Pro Ser 65 70 75 80 Ile Ala Arg Glu Ile Tyr Glu Met Tyr Glu Ala Val Ser Met Gln Pro 85 90 95 Ser Leu Arg Ser Glu Tyr Glu Tyr Pro Val Phe Ser His Val Gln Ala 100 105 110 Gly Met Phe Ser Pro Glu Leu Arg Thr Phe Thr Lys Gly Asp Ala Glu 115 120 125 Lys Trp Val Ser Thr Thr Lys Lys Ala Ser Gly Ser Ala Phe Trp Leu 130 135 140 Glu Val Glu Gly Asn Ser Met Thr Ala Pro Thr Gly Ser Lys Pro Ser 145 150 155 160 Phe Pro Asp Gly Met Leu Ile Leu Val Asp Pro Glu Gln Ala Val Glu 165 170 175 Pro Gly Asp Phe Cys Ile Ala Arg Leu Gly Gly Asp Glu Phe Thr Phe 180 185 190 Lys Lys Leu Ile Arg Asp Ser Gly Gln Val Phe Leu Gln Pro Leu Asn 195 200 205 Pro Gln Tyr Pro Met Ile Pro Cys Asn Glu Ser Cys Ser Val Val Gly 210 215 220 Lys Val Ile Ala Ser Gln Trp Pro Glu Glu Thr Phe Gly * 225 230 235 <210> 1098 <211> 67 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2686..2886) <400> 1098 Met Glu Gln Arg Ile Thr Leu Lys Asp Tyr Ala Met Arg Phe Gly Gln 1 5 10 15 Thr Lys Thr Ala Lys Asp Leu Gly Val Tyr Gln Ser Ala Ile Asn Lys 20 25 30 Ala Ile His Ala Gly Arg Lys Ile Phe Leu Thr Ile Asn Ala Asp Gly 35 40 45 Ser Val Tyr Ala Glu Glu Val Lys Pro Phe Pro Ser Asn Lys Lys Thr 50 55 60 Thr Ala * 65 <210> 1099 <211> 98 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3005..3298) <400> 1099 Met Val Arg Ala Asn Lys Arg Asn Glu Ala Leu Arg Ile Glu Ser Ala 1 5 10 15 Leu Leu Asn Lys Ile Ala Met Leu Gly Thr Glu Lys Thr Ala Glu Ala 20 25 30 Val Gly Val Asp Lys Ser Gln Ile Ser Arg Trp Lys Arg Asp Trp Ile 35 40 45 Pro Lys Phe Ser Met Leu Leu Ala Val Leu Glu Trp Gly Val Val Asp 50 55 60 Asp Asp Met Ala Arg Leu Ala Arg Gln Val Ala Ala Ile Leu Thr Asn 65 70 75 80 Lys Lys Arg Pro Ala Ala Thr Glu Arg Ser Glu Gln Ile Gln Met Glu 85 90 95 Phe * <210> 1100 <211> 203 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3331..3939) <400> 1100 Met Thr Asn Thr Ala Lys Ile Leu Asn Phe Gly Arg Gly Asn Phe Ala 1 5 10 15 Gly Gln Glu Arg Asn Val Ala Asp Leu Asp Asp Gly Tyr Ala Arg Leu 20 25 30 Ser Asn Met Leu Leu Glu Ala Tyr Ser Gly Ala Asp Leu Thr Lys Arg 35 40 45 Gln Phe Lys Val Leu Leu Ala Ile Leu Arg Lys Thr Tyr Gly Trp Asn 50 55 60 Lys Pro Met Asp Arg Ile Thr Asp Ser Gln Leu Ser Glu Ile Thr Lys 65 70 75 80 Leu Pro Val Lys Arg Cys Asn Glu Ala Lys Leu Glu Leu Val Arg Met 85 90 95 Asn Ile Ile Lys Gln Gln Gly Gly Met Phe Gly Pro Asn Lys Asn Ile 100 105 110 Ser Glu Trp Cys Ile Pro Gln Asn Glu Gly Lys Ser Pro Lys Thr Arg 115 120 125 Asp Lys Thr Ser Leu Lys Leu Gly Asp Cys Tyr Pro Ser Asn Trp Gly 130 135 140 Ile Ala Ile Pro Gln Asn Arg Gly Thr Gln Lys Thr Leu Leu Gln Lys 145 150 155 160 Lys Lys Glu Lys Ile Ile Arg Pro Arg Ile Leu Ala Asn Pro Leu Thr 165 170 175 Ser Gln Lys Thr Ile Phe Leu Trp Leu Asn Arg Met Leu Gln Phe Arg 180 185 190 Ala Ala Ala Ser Gly Glu Gln Gln Lys Thr * 195 200 <210> 1101 <211> 171 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3741..4253) <400> 1101 Leu Leu Ser Leu Lys Leu Gly Asp Cys Tyr Pro Ser Lys Gln Gly Asp 1 5 10 15 Thr Lys Asp Thr Ile Thr Lys Glu Lys Arg Lys Asp Tyr Ser Ser Glu 20 25 30 Asn Ser Gly Glu Ser Ser Asp Gln Pro Glu Asn Asp Leu Ser Val Val 35 40 45 Lys Pro Asp Ala Ala Ile Gln Ser Gly Ser Lys Trp Gly Thr Ala Glu 50 55 60 Asp Leu Thr Ala Ala Glu Trp Met Phe Asp Met Val Lys Thr Ile Ala 65 70 75 80 Pro Ser Ala Arg Lys Pro Asn Phe Ala Gly Trp Ala Asn Asp Ile Arg 85 90 95 Leu Met Arg Glu Arg Asp Gly Arg Asn His Arg Asp Met Cys Val Leu 100 105 110 Phe Arg Trp Ala Cys Gln Asp Asn Phe Trp Ser Gly Asn Val Leu Ser 115 120 125 Pro Ala Lys Leu Arg Asp Lys Trp Thr Gln Leu Glu Ile Asn Arg Asn 130 135 140 Lys Gln Gln Ala Gly Val Thr Ala Ser Lys Pro Lys Leu Asp Leu Thr 145 150 155 160 Asn Thr Asp Trp Ile Tyr Gly Val Asp Leu * 165 170 <210> 1102 <211> 104 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4250..4561) <400> 1102 Met Lys Asn Ile Ala Ala Gln Met Val Asn Phe Asp Arg Glu Gln Met 1 5 10 15 Arg Arg Ile Ala Asn Ile Asp Asn Gln Asp Met Thr Ile Ser Val Trp 20 25 30 Val Phe Pro Asp Thr Asp Ile Ser Asp Val Ser Arg Glu Leu Ile Ala 35 40 45 Ala Ile Lys Gln Gly Tyr Leu Thr Val Lys Ala Ala Gly Val Trp Ala 50 55 60 Gly Gly Ile Glu Thr Pro Ser Val Glu Thr Pro Ser Glu Gly Ser Lys 65 70 75 80 Phe Phe Gly Phe Asp Met Asp Asn Glu Phe Ile Ser Gly Phe Asp Val 85 90 95 Gly Ala Trp Gly Val Leu Leu * 100 <210> 1103 <211> 265 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4561..5355) <400> 1103 Met Ala Lys Asn Asp Phe Lys Ala Phe Ala Thr Asp Arg Asn Ala Asn 1 5 10 15 Val Met Ser Gln Glu Glu Trp Glu Ala Leu Pro Ala Leu Ile Ser Gly 20 25 30 Phe Thr Ala Gly Lys Ala Ser Ser Ala Gln Val Asn Lys Val Ile Arg 35 40 45 Gln Ala Ser Phe Ile Ala Ala Ala Leu Ala Gln Phe Val Ser Asp Lys 50 55 60 Thr Gln Arg Asp Val Leu Asp Asn Gly Asp Leu Pro Gly Phe Val Glu 65 70 75 80 Leu Leu Gly Ser Gly Phe Ala Val Glu Tyr Leu Ser Arg Lys Asn Pro 85 90 95 Phe Gly Asp Ile Lys Ser Asp Gly Thr Val Lys Thr Ala Leu Gln Asn 100 105 110 Leu Gly Leu Gly Glu Gly Ala Pro Ala Ile Gly Val Pro Phe Phe Trp 115 120 125 Pro Ser Ala Ala Met Pro Asn Thr Val Ile Asp Ser Trp Ser Cys Met 130 135 140 Val Phe Leu Lys Phe Asn Gly Ala Lys Phe Ser Ala Thr Asp Tyr Pro 145 150 155 160 Val Leu Ala Lys Val Phe Pro Ser Leu Val Leu Pro Glu Ala Arg Gly 165 170 175 Asp Phe Ile Arg Ile Trp Asp Asp Gly Arg Gly Ala Asp Gly Gly Arg 180 185 190 Glu Leu Leu Ser Trp Gln Ala Ala Thr Asn Phe Ser Gln Phe Ala Gly 195 200 205 Asn Ile Gly Glu Gly Ala Gly His Ala Ile Asn Phe His Asp Gly Ile 210 215 220 Ala Gly Asn Gln Pro Gly Phe Ser Arg Phe Asn Phe Thr Ser Asn Ser 225 230 235 240 Val Gly Asp Gly Val Asn Phe Val Ala Val Arg Pro Arg Asn Ile Ala 245 250 255 Phe Asn Phe Leu Val Arg Ala Lys * 260 <210> 1104 <211> 198 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5355..5948) <400> 1104 Met Lys Pro Val Phe Asp Glu Asn Gly Leu Ala Thr Val Pro Gly Asp 1 5 10 15 Met Arg Cys Phe Tyr Tyr Asp Ala Glu Thr Ser Glu Tyr Thr Gly Trp 20 25 30 Ser Asp Glu Tyr Ile Asn Thr Gly Val Ser Met Pro Ala Cys Ser Thr 35 40 45 Gly Ile Asp Pro Gly Glu Asn Ile Pro Gly Arg Val Ala Val Phe Thr 50 55 60 Gly Lys Gly Trp Ser His Glu Glu Asp His Arg Asn Glu Thr Val Tyr 65 70 75 80 Ser Ile Glu Asn Gly Ala Ala Val Thr Val Asp Tyr Ile Gly Ala Ile 85 90 95 Lys Asp Gly Tyr Val Thr Ile Ser Pro Leu Thr Pro Tyr Asp Lys Trp 100 105 110 Asp Gly Glu Lys Trp Val Thr Asp Thr Glu Ala Gln His Ser Ala Ala 115 120 125 Val Asp Ala Ala Glu Ala Gln Arg Gln Ser Leu Ile Asp Ala Ala Met 130 135 140 Ala Ser Ile Ser Leu Ile Gln Leu Lys Leu Gln Ala Gly Arg Lys Leu 145 150 155 160 Thr Gln Ala Glu Thr Thr Arg Leu Asn Ala Val Leu Asp Tyr Ile Asp 165 170 175 Ala Val Thr Ala Thr Asp Thr Ser Thr Ala Pro Asp Val Ile Trp Pro 180 185 190 Glu Leu Pro Glu Ala * 195 <210> 1105 <211> 148 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5920..6363) <400> 1105 Met Asp Glu Tyr Val Tyr Ser Ala Arg His Asn Ala Phe Phe Pro Val 1 5 10 15 Asp Met Ile Asp Lys Tyr Lys Ser Glu Gly Trp Asp Leu Ser Asp Ala 20 25 30 Lys Glu Val Asn Gln Asn Ile Ile Ser Glu Phe Met Ala Glu Pro Pro 35 40 45 Gln Gly Lys Ile Arg Ile Ala Gly Asp Asp Gly Leu Pro Ala Trp Ala 50 55 60 Asp Ile Pro Pro Pro Thr His Glu Glu Leu Ile Glu Ile Thr Glu Ser 65 70 75 80 Glu Arg Gln Leu Leu Ile Asn Gln Ala Asn Glu Tyr Met Asn Ser Lys 85 90 95 Gln Trp Pro Gly Lys Ala Ala Ile Gly Arg Leu Lys Gly Asp Glu Leu 100 105 110 Thr Gln Tyr Asn Leu Trp Leu Asp Tyr Leu Asp Ala Leu Glu Leu Val 115 120 125 Asp Thr Ser Gly Ala Pro Asp Ile Glu Trp Pro Thr Pro Pro Ala Val 130 135 140 Gln Ala Arg * 145 <210> 1106 <211> 137 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6384..6794) <400> 1106 Met Pro Phe Ala Arg Tyr Phe Cys Ile Phe Ile Asn Val Gly Leu Gly 1 5 10 15 Glu Ala Ala Lys Arg Asp Val Gly Thr Gly Glu Asn Gln Ile Pro Asp 20 25 30 Met Ala Ser Phe Ala Ser Gly Asn Gly Trp Met Lys Leu Pro Asn Gly 35 40 45 Lys Ile Leu Gln Tyr Gly Arg Gly Ala Val Thr Pro Thr Leu Ser Thr 50 55 60 Gln Thr Met Arg Ile Thr Phe Ser Ile Pro Phe Pro Lys Lys Ala Asp 65 70 75 80 Cys Ala Met Leu Thr His Ser Gly Asp Gly Gly Ala Pro Leu Gly Ala 85 90 95 Gly Arg Gly Phe Val Met Thr Ala Glu Gly Pro Thr Leu Thr Gly Phe 100 105 110 Asn Ser Ala Tyr Arg Thr Ser Ser Thr Ser Asp Thr Val Ser Met Asn 115 120 125 Tyr Ser Trp Trp Ala Val Gly Glu * 130 135 <210> 1107 <211> 185 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6824..7378) <400> 1107 Met Leu Ile Gly Tyr Val Arg Val Ser Thr Asn Asp Gln Asn Thr Asp 1 5 10 15 Leu Gln Arg Asn Ala Leu Asn Cys Ala Gly Cys Glu Leu Ile Phe Glu 20 25 30 Asp Lys Ile Ser Gly Thr Lys Ser Glu Arg Pro Gly Leu Lys Lys Leu 35 40 45 Leu Arg Thr Leu Ser Ala Gly Asp Thr Leu Val Val Trp Lys Leu Asp 50 55 60 Arg Leu Gly Arg Ser Met Arg His Leu Val Ile Leu Val Glu Glu Leu 65 70 75 80 Arg Glu Arg Gly Val Asn Phe Arg Ser Leu Thr Asp Ala Ile Asp Thr 85 90 95 Ser Thr Pro Met Gly Arg Phe Phe Phe His Val Met Gly Ala Leu Ala 100 105 110 Glu Met Glu Arg Glu Leu Ile Val Glu Arg Thr Lys Ala Gly Leu Glu 115 120 125 Ala Ala Arg Ala Gln Gly Arg Ile Gly Gly Arg Arg Pro Lys Leu Thr 130 135 140 Pro Glu Gln Trp Ala Gln Ala Gly Arg Leu Ile Ala Ala Gly Ile Pro 145 150 155 160 Arg Gln Lys Val Ala Ile Ile Tyr Asp Val Gly Val Ser Thr Leu Tyr 165 170 175 Lys Lys Phe Pro Ala Gly Asp Lys * 180 <210> 1108 <211> 258 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7436..8209) <400> 1108 Met Asp Ile Thr Glu Phe Pro Ser Gly Val Ile Glu His Leu Gly Trp 1 5 10 15 Tyr Val Tyr Arg Leu Ile Asp Pro Arg Asp Gly Ser Thr Phe Tyr Val 20 25 30 Gly Lys Gly Lys Gly Asn Arg Val Phe Ala His Met Arg Gly Glu Val 35 40 45 Ala Ala Ala Asp Asp Asp Asp Leu Leu Ser Asn Lys Leu Lys Gln Ile 50 55 60 Arg Glu Ile Arg Leu Ala Gly Leu Glu Val Ile His Val Ile His Arg 65 70 75 80 His Gly Met Thr Asp Glu Lys Thr Ala Tyr Glu Val Glu Ala Ala Leu 85 90 95 Ile Asp Ala Tyr Pro Gly Leu Thr Asn Ile Met Asn Gly Ala Gly Ser 100 105 110 Asn Glu Phe Gly Ala Ala His Val Lys Glu Leu Ile Ala Thr Tyr Gln 115 120 125 Pro Glu Thr Ile Thr Phe His His Lys Ala Leu Met Ile Ser Val Asn 130 135 140 Arg Ser Ala Lys Asp Ser Glu Leu Tyr Asp Ala Val Arg Phe Ser Trp 145 150 155 160 Arg Ile Asn Val Ser Arg Ala Ser Lys Ala Glu Val Ile Leu Ala Thr 165 170 175 Val Arg Gly Ile Val Arg Gly Val Phe Ile Ala Asp Lys Trp Leu Lys 180 185 190 Ser Thr Arg Glu His Phe Pro Thr Met Lys Tyr Trp Asp Glu Asp Pro 195 200 205 Asp Phe Glu Ala Thr Gln Ser Ser Arg Tyr Gly Phe Glu Gly Arg Glu 210 215 220 Ala Pro Pro Glu Ile Ala Asn Leu Tyr Leu Gly Lys Lys Ile Pro Asp 225 230 235 240 Glu Leu Arg Lys Lys Gly Ala Met Ser Pro Val Arg Tyr Ser Pro Asn 245 250 255 Phe * <210> 1109 <211> 50 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8869..9018) <400> 1109 Leu Ser Ile Ile Cys Asn Cys Asn Gly Ile Tyr Asn Pro Leu Leu Tyr 1 5 10 15 Cys Tyr Gly Ile Phe Tyr His Thr Leu Phe Leu Val Val Phe Tyr Thr 20 25 30 Glu Val Trp Gln Ser Glu Leu Tyr Ile His Ile Leu His Pro Gly Phe 35 40 45 Ser * <210> 1110 <211> 248 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9033..9776) <400> 1110 Met Ala Thr Thr Cys Ser Val Ile Leu Ile Leu Glu Ser Phe Asp Val 1 5 10 15 Tyr Phe Gly Lys Glu Ser Val Phe Leu Glu Arg Gly Ser Ser Val Leu 20 25 30 Val Asp Ser Ser Ser Arg Asp Phe Phe Leu Thr Tyr Pro Glu Arg Val 35 40 45 Ile Val Ala Asp Phe Gly Ala Glu Phe Ile Ser Arg Tyr Leu Lys Ala 50 55 60 Asn Asn Leu Arg Asp Ile Ser Asp Cys Arg Glu Tyr Pro Ser Tyr Leu 65 70 75 80 Lys Ile Asn Phe Ala Asp Phe Ser Leu Ile Lys Gly Leu Ile Ser Trp 85 90 95 Ala Asn His Cys Ala Glu Tyr Ile Glu Ile Phe Asp Glu Ser Ile Ala 100 105 110 Phe Thr Cys Leu Ser Ala Phe Ser Ser Glu Lys Gln Phe Gly Val Phe 115 120 125 Leu Phe Gly Cys Leu Lys Ser Thr Gly Ala Lys Val Lys Thr Ile Ile 130 135 140 His Thr Asp Leu Ser Ala Pro Trp Arg Leu Lys Asp Ile Ser Ser Arg 145 150 155 160 Leu Tyr Leu Ser Glu Ser Leu Leu Lys Arg Lys Leu Lys Glu Glu Gly 165 170 175 Val Ser Phe Ser Lys Ile Ile Leu Asp Glu Arg Met Gln Met Ala Glu 180 185 190 Tyr Leu Leu Ser Thr Arg Cys Tyr Pro Ile Ser Lys Val Ala Lys Val 195 200 205 Cys Gly Tyr Ala Ser Val Ser Tyr Phe Thr Tyr Val Phe Arg Arg Tyr 210 215 220 Phe Gly Val Ser Pro Ser Gln Tyr Ser Gln Arg Ser Ser Glu Ser Lys 225 230 235 240 Ile Leu Thr His Gln Gly Ile * 245 <210> 1111 <211> 118 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9818..10171) <400> 1111 Met Leu Gly Ala Ile Glu Lys Arg Phe Gly Asp Lys Val Pro Glu Gln 1 5 10 15 Ser Ile Gln Trp Leu Thr Asp Asn Gly Ser Ala Tyr Arg Ala His Glu 20 25 30 Thr Arg Gln Phe Ala Arg Glu Leu Asn Leu Glu Pro Cys Thr Thr Ala 35 40 45 Ile Ser Ser Pro Gln Ser Asn Gly Ile Ala Glu Arg Phe Val Lys Thr 50 55 60 Met Lys Glu Asp Tyr Ile Ala Phe Met Pro Lys Pro Asn Val Arg Thr 65 70 75 80 Ala Leu His Asn Leu Ala Val Ala Ile Glu His Tyr Asn Glu Asn His 85 90 95 Pro His Ser Ala Leu Gly Tyr Arg Ser Pro Arg Glu Tyr Arg Arg Gln 100 105 110 Arg Val Thr Leu Thr * 115 <210> 1112 <211> 394 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10739..11920) <400> 1112 Met Pro Leu Asn Asp Met Gln Ile Arg Arg Ala Lys Pro Glu Ala Lys 1 5 10 15 Ala Tyr Thr Phe Gly Asp Gly Leu Gly Leu Ser Leu Leu Ile Glu Pro 20 25 30 Asn Gly Ser Lys Ser Trp Arg Phe Arg Tyr Arg Tyr Ala Gly Lys Pro 35 40 45 Lys Met Ile Ser Leu Gly Val Tyr Pro Thr Ile Thr Leu Ala Asp Ala 50 55 60 Arg Ser Arg Arg Asp Glu Ala Arg Lys Leu Val Ala Glu Gly Lys Asn 65 70 75 80 Pro Ser Glu Val Arg Lys Glu Gln Lys Leu Ala Met Gln Thr Glu Ser 85 90 95 Glu Asn Ala Phe Glu Lys Ile Ala Arg Glu Trp His Gln Leu Lys Ser 100 105 110 Ala Lys Trp Ser Ala Gly Tyr Ala Ser Asp Ile Met Glu Ala Phe Lys 115 120 125 Asn Asp Ile Phe Pro Tyr Val Gly Thr Arg Pro Val Gly Glu Ile Lys 130 135 140 Pro Leu Glu Leu Leu Asn Val Leu Arg Lys Ile Glu Lys Arg Gly Ala 145 150 155 160 Leu Glu Lys Met Arg Lys Val Arg Gln Arg Cys Ser Glu Val Phe Arg 165 170 175 Tyr Ala Ile Ala Thr Gly Arg Ala Glu Tyr Asn Pro Ala Ala Asp Leu 180 185 190 Ser Ser Ala Leu Glu Val His Gln Ser Asn His Phe Pro Phe Leu Lys 195 200 205 Ala Asp Glu Ile Pro Asp Phe Leu Arg Ala Leu Glu Gly Tyr Ser Gly 210 215 220 Ser Lys Leu Val Gln Ile Ala Thr Lys Leu Leu Met Ile Thr Gly Val 225 230 235 240 Arg Thr Ile Glu Leu Arg Ala Ala Leu Trp Gln Glu Phe Asp Leu Asp 245 250 255 Asn Ala Ile Trp Glu Ile Pro Ala Glu Arg Met Lys Met Arg Arg Pro 260 265 270 His Leu Val Pro Leu Ser Ser Gln Ala Val Asp Leu Leu Asn Glu Leu 275 280 285 Lys Ile Met Thr Gly Asn Tyr Arg Tyr Val Phe Pro Gly Arg Asn Asp 290 295 300 Pro Asn Arg Pro Met Ser Glu Ala Ser Ile Asn Gln Ala Ile Lys Arg 305 310 315 320 Ile Gly Tyr Gly Gly Lys Val Thr Gly His Gly Phe Arg His Thr Leu 325 330 335 Ser Thr Ile Leu His Glu Gln Gly Phe Glu Ser Ala Trp Ile Glu Ile 340 345 350 Gln Leu Ala His Val Asp Lys Asn Ser Ile Arg Gly Thr Tyr Asn His 355 360 365 Ala Gln Tyr Phe Ser Gly Arg Lys Ser Met Met Asp Trp Tyr Ser Asn 370 375 380 Leu Ile Phe Glu Arg Leu Lys Arg Ser * 385 390 <210> 1113 <211> 139 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11924..12340) <400> 1113 Val Ser Gln Pro Leu Ser Glu Ile Leu Thr Trp Asp Asp Glu Gln Trp 1 5 10 15 Glu Val Phe Val His Asp Trp Leu Ile Val Cys Lys Ser Asp Asp Tyr 20 25 30 Pro Trp Ser Glu Arg Leu Gly Gly Ala Gly Asp Lys Gly Arg Asp Val 35 40 45 Val Gly Tyr Lys Ser Asp Pro Asn Val Glu Gly Tyr Ser Trp Asp Asn 50 55 60 Tyr Gln Cys Lys Leu Tyr Lys Lys Ser Leu Gly Phe Ser Asp Val Val 65 70 75 80 Val Glu Phe Gly Lys Leu Ile Tyr Phe Thr Leu Asn Gly Asp Tyr Pro 85 90 95 Ile Pro Gln Lys Tyr Phe Phe Val Ala Pro Tyr Asp Leu Ser Thr Thr 100 105 110 Phe Ser Asn Leu Leu Lys Asn Lys Asn Glu Leu Lys Lys Ala Val Leu 115 120 125 Asp Ser Trp Asp Ser Ala Ile Ser Lys Lys * 130 135 <210> 1114 <211> 206 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12313..12930) <400> 1114 Met Gly Phe Ser Asn Phe Lys Lys Ile Thr Lys Lys Ile Asp Ile Pro 1 5 10 15 Leu Asp Asp Glu Ile Lys Lys Tyr Ile Glu Asp Phe Asp Phe Ser Ile 20 25 30 Phe Tyr Ser Leu Pro Leu Ser Leu Ile Leu Asn Asp Ile Ala Asn Thr 35 40 45 His Leu Tyr Phe Lys Tyr Phe Asn Glu Leu Tyr Val Val Arg Ile Pro 50 55 60 Pro Asn Glu Ile Pro Thr Tyr Asn Ser Lys Lys Glu Ser Val Tyr Val 65 70 75 80 Asn Ala Leu Leu Gln Ala Tyr Ser Glu His Gly Asn Lys Thr Tyr Ser 85 90 95 Ser Phe Leu Glu Leu Asp Asp Pro Tyr Arg Arg His Phe Asn Asn Ser 100 105 110 Arg Asn Asp Phe Tyr Phe Ala Ser Ser Leu Glu Val Phe Val Arg Glu 115 120 125 Val Phe Lys Asp Asp Val Phe Lys Ala Leu Lys Cys Tyr Ile Ser Ser 130 135 140 Ser Ile Glu Pro Val Phe Tyr Glu Asp His Asn Tyr Ala Phe Ile Arg 145 150 155 160 Cys Asn Ala Val Leu Lys Gln Ala Val Leu Thr Pro Ile Ala His Ser 165 170 175 Val Leu Ser Lys Ile Cys Glu Ala Asn Asp Lys Lys Gly Ile Cys His 180 185 190 His Leu Val Asn Asp Gly Glu Val Ile Trp Thr Val Arg * 195 200 205 <210> 1115 <211> 153 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12930..13388) <400> 1115 Met Val Arg Ile Tyr Asn Ser Ser Leu Glu Val Ala Cys Arg Met Ala 1 5 10 15 Lys Val Leu Val Ala Ile Tyr Pro Ser Ser Leu Ser Leu Glu Arg Leu 20 25 30 Ile Cys Phe Asp Phe Ile Leu Val Asn Leu Lys Asp Phe Leu Pro Glu 35 40 45 Glu Ile Ser Leu His Pro Pro Ile Pro Arg Arg Asp Ala Gln Leu Ala 50 55 60 Leu Lys Arg Glu Ile Val Leu Glu Ser Leu Ala Leu Leu Gln Gly Tyr 65 70 75 80 Glu Leu Ala Ser Lys Ile Tyr Thr His Arg Gly Phe Val Tyr Lys Ala 85 90 95 Ser Glu Lys Thr Tyr Ala Phe Thr Asn Ser Leu His Asn Glu Tyr Val 100 105 110 Ala Gln Met Glu His Asn Ile Asn Leu Val Val Lys Leu Tyr Ser Asp 115 120 125 Ile Pro Asp Glu Gln Leu Gln Ser Ile Ile Lys Asn Lys Ile Gly Lys 130 135 140 Tyr Asp Met Glu Phe Asn Tyr Glu * 145 150 <210> 1116 <211> 211 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13381..14013) <400> 1116 Met Asn Asp Asn Phe Phe Thr Phe Arg Lys Ile Lys Val Thr Gly Phe 1 5 10 15 Asn Lys Leu Asp Ala Ile Ile Glu Phe Gly Ser Lys Leu Thr Ile Leu 20 25 30 Tyr Gly Gly Ser Asp Ser Gly Lys Thr Tyr Ile Tyr Tyr Leu Ile Arg 35 40 45 Tyr Leu Leu Gly Ser Glu Lys Leu Lys Asn Lys Asp Ile Asp His Ala 50 55 60 Gln Gly Tyr Asp Leu Ala Tyr Leu Glu Phe Asn Phe Gln Gly Arg Val 65 70 75 80 Met Thr Ile Glu Arg Ser Leu Gln Asp Ser Ala His Tyr Arg Leu Tyr 85 90 95 Asp Ser Ser Ile Glu Asn Val Ser Glu Ala Asn Leu Leu Met Val Phe 100 105 110 Ser Lys Ser Ala Ser Ser Lys Lys Ser Phe Ser Ser Tyr Phe Tyr Gly 115 120 125 Arg Leu Asn Phe Lys Glu Ala Lys Val Arg Thr Asn Leu Ser Asn Thr 130 135 140 Leu His Lys Phe Asn Leu Asn Asn Val Phe Glu Phe Phe Cys Ile Asp 145 150 155 160 Glu Leu Arg Val Leu Thr Glu Lys Ser Leu Ile Leu Ser Asp Ile Pro 165 170 175 Ser Glu Glu Thr Lys Arg Lys Ser Glu Phe Lys Phe Leu Leu Thr Gln 180 185 190 Arg Asp Asp Thr Asn Ser Leu Ala Glu Lys Pro Asn Lys Lys Ala Arg 195 200 205 Tyr Phe * 210 <210> 1117 <211> 197 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14044..14634) <400> 1117 Leu Lys Ala Gln Leu Ile Tyr Pro Glu Tyr Asp Gln Val Ile Val Ser 1 5 10 15 Arg Glu Leu Glu Lys Val Glu Gln Asp Ile Glu Ser Ser Lys Asp Ile 20 25 30 Leu Lys Gly Ile Val Asp Ala Leu Asp Asp Lys Lys Gln Leu Leu Lys 35 40 45 Glu Leu Ser Asp Glu Leu Tyr Ser Ile Ser Asp Arg Glu Lys Tyr Leu 50 55 60 Ser Leu Leu Ile Glu Arg Phe Ser Leu Leu Lys Asp Gln Tyr Phe Ile 65 70 75 80 Asp Leu Gln Arg Ile Asp Val Val Ser Gln Ala Asn Phe Tyr Leu Asn 85 90 95 Asn Phe Ala Asp Ile Tyr Cys Glu Phe Cys Asn Thr Pro Gln Lys Lys 100 105 110 Glu Asn Glu Ile Ser Tyr Asp Asp Cys Phe Leu Ser Cys Asn Ala Glu 115 120 125 Lys Leu Lys Ile Lys Ser Gln Leu Lys Gly Leu Ile Glu Ser Ile Gly 130 135 140 Ser Asn Val Arg Glu His Glu Leu Ile Met Leu Arg Lys Asn Asp Val 145 150 155 160 Asn Glu Ile Tyr Gln Ser Glu Lys Ser Asp Phe Lys Thr Leu Glu Asp 165 170 175 Lys Asn Ile Lys Gln Tyr Ile His Leu Leu Asn His Phe Met Asn Ile 180 185 190 Lys Thr Ile Phe * 195 <210> 1118 <211> 189 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14634..15200) <400> 1118 Met Asp His Thr Lys His Ser Ile Leu Ser Ser Leu Gln Asp Lys Glu 1 5 10 15 Asp Asp Val Asp Glu Leu Lys Tyr Ser Ala Glu Asp Phe Asp Ser Leu 20 25 30 Thr Val Ala Asp Leu Tyr Asp Ile Glu Ile Ala Met Gln Asp Phe Leu 35 40 45 Asn Asp Ile Asn Phe Glu Asn Ser Lys Asp Asn Lys Val Arg Phe Asp 50 55 60 Glu Asp Thr Tyr Asp Phe Asn Ile Asn Gly Lys Arg Arg Gly Met Phe 65 70 75 80 Gly Lys Gly Thr Arg Ala Val Met His Ala Ile Phe Thr Ile Cys Phe 85 90 95 Ala Glu Phe Leu Ser Arg Lys Gly Asn Pro Phe Ile Gly Phe Val Val 100 105 110 Leu Asp Ser Pro Leu Val Thr His Phe Asp Lys Asp Arg Gly Gly Ser 115 120 125 Leu Ser Asp Val Asn Ser Val Ser Leu Ser Asp Ser Phe Tyr His Ala 130 135 140 Leu Ile Lys Arg Asp Tyr Asn Phe Gln Ile Val Ile Leu Glu Asn Lys 145 150 155 160 Gly Pro Thr Phe Gln Ile Lys Ile Asn Asp Ala Asn Lys Ile His Asn 165 170 175 Leu Asn Lys Asn Gly Ser Ser Gly Phe Tyr Pro Val * 180 185 <210> 1119 <211> 91 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15610..15882) <400> 1119 Met Ala Leu Lys Cys Pro Glu Cys Gly Thr Thr Ala His Ala Arg Thr 1 5 10 15 Ser Ala Tyr Glu Ala Pro Ser Val Lys Arg Ser Trp Tyr Gln Cys Gln 20 25 30 Asn Leu Glu Cys Ser Tyr Thr Phe Thr Ala Leu Glu Ser Val Asp Thr 35 40 45 Ile Ile Met Lys Pro Arg Arg Asn Glu Gln Glu Ser Glu Lys Ala Gln 50 55 60 Met Pro Glu Lys Gln Gln Gln Thr Leu Asn Arg Tyr Gly Ser Ala Ser 65 70 75 80 Lys Leu Ser Ser Arg Gln Gln Ile Pro Val * 85 90 <210> 1120 <211> 184 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15888..16439) <400> 1120 Met Met Ala Arg Val Thr Pro Asp Gln Ala Leu Ile Ser Phe Arg Asn 1 5 10 15 Ala Arg Ile Leu Trp Ala Gly His Ser Glu Ser Arg Lys Ala Val Glu 20 25 30 Gln Gln Ile Glu Ser Leu Leu Thr Ala Met Glu Lys Pro Ala Asp Tyr 35 40 45 Ala Arg Gln Leu Glu Leu Gln Arg Glu His Leu Asp Val Leu Lys Trp 50 55 60 Gln Ile Asn Cys Ala Ala Arg Glu Cys Ile Tyr Ser Gln His Gln Leu 65 70 75 80 Met Glu Ala Cys Thr Glu Asp Ala Leu Ser Asn Phe Met Gln Ala Asn 85 90 95 Gly Ala Ala Leu Thr Ser Ala Leu Ala Pro Phe Leu Lys Gly Arg Gly 100 105 110 Gly Val Asp Val Ala Ser Arg Ile Leu Arg Asn Ala Leu Val Arg Gln 115 120 125 Leu Ala Ile Thr Pro Pro Glu Ile Ala Gly Asp Tyr Arg Met Ile Leu 130 135 140 Asp Glu Ser Gly Val Met Pro Asp Pro Met Met Val Arg Asp Cys Gln 145 150 155 160 Ser Ser Tyr Thr Pro Ala Gln Gln Leu Arg Phe Gln Gln Arg Leu Asp 165 170 175 Tyr Ile Asn Gly Met Gln Glu * 180 <210> 1121 <211> 251 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16436..17188) <400> 1121 Met Thr Ile Pro Glu Gln Asn Asn Asn Pro Ile Val Glu Ile Ser Ile 1 5 10 15 Pro Val Ser Thr Gln Gln Ala Leu Glu Lys Val Asn Ala Thr Lys Ser 20 25 30 Ala Trp Leu Glu Ala Arg Arg Gln Gln Lys Ala Ala Ala Asp Asn Ile 35 40 45 Ala Thr Ile Arg Gln Arg Arg Ala Glu Met Glu Ala Thr Thr Asn Ala 50 55 60 Leu Asn Glu Glu Trp Arg Thr Leu Phe Arg Glu Ser Gln Gly Val Val 65 70 75 80 Ser Lys Glu Met Lys Lys Leu Arg Thr Glu Ile Ala Leu Gly Arg Glu 85 90 95 Thr Leu Glu Asp Phe Asp Glu Leu Leu Ala Ala Gln Glu Ser Glu Asn 100 105 110 Ala Leu Leu Pro Gln Glu Ala Ala Glu Leu Ala Gly Lys Tyr Ile His 115 120 125 Ala His Asp Thr Leu Val Gly Ile Arg Ala Lys Gln Ile Trp Glu Asp 130 135 140 Phe Met Gln Ser His Gly Lys Ala Leu Ile Gln Thr Leu Ser Leu Leu 145 150 155 160 Lys Ser Thr Met Gly Arg Glu Ala Ser Ala Val Val Gly Val Val His 165 170 175 Ser Val Asn Asp Pro Asp Thr Leu Leu Lys Asp Phe Ile His Lys His 180 185 190 Ile Thr Arg Pro Ala Leu Thr Asn Asp Ala Met Pro Glu Gln Asp Pro 195 200 205 Val Phe Lys Leu Ala Gly Val Ala Pro Asp Tyr Ala Ala Arg Leu Asp 210 215 220 Phe Ser Asn Lys Leu Ser Pro Ala Ala Met His Lys Met Lys Val Arg 225 230 235 240 Gln Glu Arg Ala Glu Lys Glu Lys Ala Val * 245 250 <210> 1122 <211> 87 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18122..18382) <400> 1122 Met Arg Asn Ile Ser Val Ser Ala Pro Ala Pro Ala Ala Pro Leu Phe 1 5 10 15 Pro Val Ser Asn His His Glu Arg Phe Leu Arg Leu Pro Glu Val Met 20 25 30 His Leu Cys Gly Leu Ser Arg Ser Thr Val Tyr Asp Leu Ile Ser Arg 35 40 45 Asp Ala Phe Pro Lys Gln Ile Pro Leu Gly Gly Lys Asn Val Ala Trp 50 55 60 Ala Gln Ser Glu Val Ser Ala Trp Met Ala Asp Arg Ile Ser Ala Arg 65 70 75 80 Gly Arg Gly Cys Asp Ala * 85 <210> 1123 <211> 186 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18379..18936) <400> 1123 Met Met Ile Pro Ala Tyr Ile Lys Tyr Leu Tyr Ser Gly Leu Leu Thr 1 5 10 15 Val Val Ile Ser Arg Tyr Ser Phe Ser Ala Val Ala Lys Ser Ala Ala 20 25 30 Gly Ile Gly Val Pro Tyr Asn Leu Leu Ala Thr Ile Asp Ala Pro Cys 35 40 45 Val Phe Phe Tyr Val Val Ala Gln Ala Gln Pro Phe Ser Gly Leu Trp 50 55 60 Cys Leu Cys Leu His His Gly Ser Ile Glu Ile Met Val Val Arg Ala 65 70 75 80 Gly Gln Pro Ser Gly Trp Pro Val Ser Asn Lys Ala Gly Tyr Ala Asn 85 90 95 Pro Val Arg Ala Ala Thr Ser Glu Ile Gly Val Ser Gly Gly Ser Asn 100 105 110 Asn Arg Tyr Leu Leu Glu Ala Ala Ile Met Ala Thr Ile Leu Thr Pro 115 120 125 Ser His Pro Gln Tyr Val Phe Val Phe Ala Ala Ile Arg Arg Ala Asp 130 135 140 Thr His Pro Arg Ile Cys Met Leu Arg Thr Val Ser Cys Asp Glu Arg 145 150 155 160 Ser Ala Arg Arg Leu Leu Val Arg Asp Tyr Val Leu Ser Leu Ser Ala 165 170 175 Arg Leu Pro Ala Gly Glu Val Thr Leu * 180 185 <210> 1124 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18933..19154) <400> 1124 Met Asn Gln Phe Glu Ile Ser Tyr Asp Asp Val Val Arg Leu Lys His 1 5 10 15 Leu Arg Asn Val Gly Glu Tyr Val Thr Gly Met Ala Ala Leu Gln Asp 20 25 30 Cys Tyr Glu Lys Pro Ala Gly Ala Gln Cys Glu Gln Leu Val Ser Leu 35 40 45 Ile Tyr Leu Met Thr Glu Gln Leu Asp Gly Val Val Gln Arg Cys His 50 55 60 Asp Asp Leu Met Asn Ala Glu Val Ala * 65 70 <210> 1125 <211> 108 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19154..19477) <400> 1125 Met Ile Cys Cys Glu Ser Leu Leu Ala Leu Arg Ala Ala Leu Tyr Arg 1 5 10 15 Arg Ala Val Ala Cys Ala Trp Leu Ala Leu Ser Asn His Gln Glu Arg 20 25 30 Tyr Ser Gly Leu Thr Leu Ala Glu Leu Glu Asp Ala Ile Ala Arg Glu 35 40 45 Leu Glu Gly Phe Tyr Leu Arg Gln His Gly Gln Gln Arg Gly Leu Glu 50 55 60 Ile Ala Cys Ala Leu Leu Ser Asp Leu Met Glu Ser Gly Pro Leu Lys 65 70 75 80 Ala Cys Pro Val Leu Ser Leu Leu Gly Met Thr Val Met Asp Glu Leu 85 90 95 Cys Ser Arg His Leu Asn Lys Pro Ala Leu His * 100 105 <210> 1126 <211> 778 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19491..21824) <400> 1126 Met Ser Gly Met Lys Val Ser Gln Ala Glu Lys Ala Ala Arg Gly His 1 5 10 15 Trp Ser Arg Ile Leu Pro Ala Leu Gly Val Asn Val Leu Lys Asn Arg 20 25 30 His Gln Pro Cys Pro Val Cys Ala Gly Lys Asp Arg Phe Arg Phe Asp 35 40 45 Asp Gln Glu Gly Arg Gly Thr Trp Phe Cys Asn Gln Cys Gly Ala Gly 50 55 60 Asp Gly Leu Ala Leu Val Ser Lys Val Leu Asp Val Gly Ile Ser Glu 65 70 75 80 Ala Ala Asp Arg Ile Asn Gly Ile Ile Gly Asn Leu Leu Pro Val Ser 85 90 95 Gln Gly Met Leu Glu Ser Gly Ser Pro Glu Lys Glu Asp Gly Arg Lys 100 105 110 Ala Ala Ala Val Leu Ala Ala Arg Leu Phe Asp Lys Ser Arg Gln Thr 115 120 125 Thr Gly Asn Ala Tyr Leu Thr Ser Lys Gly Phe Pro Ala Leu Pro Cys 130 135 140 Arg Glu Leu Thr Ala Met His Lys Val Gly Gly Val Ala Phe Arg Ala 145 150 155 160 Gly Asp Leu Val Val Pro Leu Tyr Ala Asp Gly Glu Leu Val Asn Leu 165 170 175 Gln Leu Ile Asn Ala Asn Gly Gly Lys Cys Phe Leu Lys Gly Gly Gln 180 185 190 Val Lys Asn Ala Phe Tyr Leu Val Glu Gly Thr Ala Lys Ala Ala Lys 195 200 205 Arg Leu Trp Ile Ala Glu Gly Tyr Ala Thr Ala Leu Thr Ile Asn Tyr 210 215 220 Leu Thr Gly Asp Ala Val Met Val Ala Phe Ser Ser Val Asn Phe Leu 225 230 235 240 Ser Leu Ala Ser Ile Ala Cys Ser Glu Tyr Pro Thr His Gln Ile Ile 245 250 255 Ile Ala Ala Asp Arg Asp Leu Asn Gly Ala Gly Gln Thr Arg Gly Ala 260 265 270 Ala Val Thr Gly Ala Cys Asn Cys Thr Met Ala Leu Pro Pro Val Phe 275 280 285 Gly Asp Trp Asn Asp Ala Phe Thr Gln Asn Gly Glu Glu Ala Thr Arg 290 295 300 His Ala Ile His Glu Val Ile Lys Pro Ala Val Ala Ser Pro Phe Asp 305 310 315 320 Thr Met Ser Glu Ala Glu Phe Thr Ala Leu Ser Val Ser Glu Lys Ala 325 330 335 Gln Arg Val Val Asp His Tyr Lys Asn Ser Leu Ala Val Asp Pro Asn 340 345 350 Gly Gln Leu Leu Ser Arg Tyr Glu Ala Gly Ala Trp Lys Val Ile Tyr 355 360 365 Tyr Ala Asp Phe Ala Arg Asp Val Ala Ala Leu Phe Gln Arg Leu Asp 370 375 380 Ala Pro Phe Ser Ser Ala Lys Ile Ala Ser Leu Val Glu Thr Leu Lys 385 390 395 400 Leu Ile Val Pro Gln Gln Gln Asn Pro Ala Arg Gln Leu Ile Gly Phe 405 410 415 Arg Asn Gly Val Leu Asp Thr Arg Thr Gly Leu Phe Ser Pro His Asp 420 425 430 Lys Lys His Trp Leu Arg Thr Leu Cys Glu Val Asp Tyr Thr Gln Pro 435 440 445 Val Asp Gly Glu Ser Leu Glu Thr His Ala Pro Ala Phe Trp Arg Trp 450 455 460 Leu Asp Arg Ala Ala Gly Phe Asn Pro Glu Lys Arg Asp Ile Ile Leu 465 470 475 480 Ala Ala Leu Phe Met Val Leu Ala Asn Arg Tyr Asp Trp Gln Leu Phe 485 490 495 Leu Glu Val Thr Gly Pro Gly Gly Ser Gly Lys Ser Ile Leu Ala Glu 500 505 510 Ile Ala Thr Met Leu Ala Gly Glu Asp Asn Ala Thr Ser Ala Thr Ile 515 520 525 Glu Met Leu Glu Ser Pro Arg Glu Arg Ala Ala Leu Ile Gly Phe Ser 530 535 540 Leu Ile Arg Leu Pro Asp Gln Glu Lys Trp Ser Gly Asp Gly Ala Gly 545 550 555 560 Leu Lys Ala Ile Thr Gly Gly Asp Ala Val Ser Val Asp Pro Lys Tyr 565 570 575 Gln Asn Ala Tyr Ser Thr His Ile Pro Ala Val Ile Leu Ala Val Asn 580 585 590 Asn Asn Pro Met Arg Phe Thr Asp Arg Ser Gly Gly Val Ser Arg Arg 595 600 605 Arg Val Ile Leu His Phe Pro Asp Gln Ile Ala Pro Glu Glu Arg Asp 610 615 620 Thr Gln Leu Lys Glu Lys Ile Ala Ser Glu Leu Ala Val Ile Val Arg 625 630 635 640 Gln Leu Met Gln Arg Phe Ser Asp Pro Met Ser Ala Arg Thr Leu Leu 645 650 655 Gln Ser Gln Gln Asn Ser Asp Glu Ala Leu Thr Ile Lys Arg Asp Ala 660 665 670 Asp Ser Ala Phe Asp Phe Cys Gly Tyr Leu Glu Val Leu Pro Asp Thr 675 680 685 Thr Gly Met Phe Met Gly Asn Ala Asn Ile Val Pro Arg Gln Pro Arg 690 695 700 Thr Tyr Leu Tyr His Ala Tyr Leu Val Tyr Met Glu Ala Asn Gly Tyr 705 710 715 720 Lys Asn Thr Leu Ser Leu Thr Met Phe Gly Lys Gly Leu Pro Leu Met 725 730 735 Leu Lys Glu Tyr Gly Leu Gln Tyr Glu Lys Arg Arg Thr Asn Gln Gly 740 745 750 Met Gln Thr Asn Leu Ala Leu Arg Glu Glu Ser Asn Ala Asp Trp Leu 755 760 765 Pro Lys Cys Asp Glu Phe Ala Ala Lys * 770 775 <210> 1127 <211> 319 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21957..22913) <400> 1127 Val Thr Ser Tyr Ser Asn Phe Ser Asn Gln Ile Lys Glu Thr Ile Asn 1 5 10 15 Asn Lys Phe Asp His Glu Ile His Asp Trp Asp Ile Ile Lys Asn Ser 20 25 30 Ile Thr Thr Leu Ile Asn Lys Asn Ile His Gly Ala Gly Arg Asn Ile 35 40 45 Val Asp Phe Ile Asp Leu Gly Asn Trp Asp Phe Ile Ser Asn Phe Ser 50 55 60 Phe Asp Asp Ser Thr Arg Arg Leu Glu Leu Glu Trp His Pro Asn Asp 65 70 75 80 Lys Phe His Ile Tyr Ile Glu Ser Val Val Phe Val Glu Phe Asn Asp 85 90 95 Thr Ile Tyr Ala Phe Leu Lys Gly Tyr Tyr His Asn Gln Leu Ser Leu 100 105 110 Asn Arg Ile Tyr Asn Thr Lys Cys Ser Ser Cys Ser Phe Glu Asn Ser 115 120 125 Gly Ser Tyr Met Val Asp Val Tyr Arg Thr Val Lys Arg Val Asn Glu 130 135 140 Thr Ile Gln Thr Pro Asn Ile Asn Cys Tyr Thr Thr Cys Ile Leu Thr 145 150 155 160 Arg Pro Ala Asn Gly His Val Thr Ser Thr Gly Phe Ser Arg Asn Leu 165 170 175 Met Asp Ala Ile Asn Ile Ser Leu Ala Glu His Lys Ile Ala Ser Leu 180 185 190 His Asn Glu Val Met Ser Ile Glu Glu Tyr Asp Arg Asp Ser Leu Gln 195 200 205 Glu Lys Gly Asn Thr Ala Arg Arg Tyr Leu Glu Tyr Ile Leu Met Leu 210 215 220 Val Asn Ile Arg Ile Met His Leu Asn Asn Val Gln Tyr Gln Glu Gln 225 230 235 240 Met Leu Gly Ser Leu Val Ser Val Ile Glu Ala Leu Asp Tyr Glu Pro 245 250 255 Leu Met Lys Asn Asp Val Glu Ile Thr Lys Asp Ile Leu Asn Ala Cys 260 265 270 Ser His His Gly Gly Val Arg Ile Glu Lys Lys Asp Val Ile Phe Ser 275 280 285 Leu Glu Val Ile Glu Asn Leu Ile Lys Ala Ile Lys Lys Thr Asp Ile 290 295 300 Asn Lys Leu Gln Leu Asp Gly Met Phe Lys Ser Ile Gln Lys * 305 310 315 <210> 1128 <211> 23454 <212> DNA <213> Escherichia coli O157:H7 <400> 1128 aattcatatc aacggacctc cacggaggtc cgtttttcgt ttcagaacac catgatttaa 60 gtgttcttcc tccaaatcaa ttctaccgaa ctcaaccaaa ttctccccac atcaacctca 120 ttgtgtgggt ataattgcgg gcatacccca gttcgacaga atttgtaccc tctttaacgc 180 attcagaagg ctgaactatg gcactgactg acgcaaaaat ccgggctgca aagcccactg 240 acaaggctta taaactcact gacggggctg gcatgttcct gctggtacat cctaatggtt 300 cccgttactg gcgtctccgt tatcgtattc tgggtaaaga gaagactctg gcacttgttg 360 tgtatccaga agtatctctc tccgaagctc gtacaaaacg ggatgaggcc cgaaaactga 420 tttcggaggg ggttgaccct tgcgaacaga aaagagctaa aaaagtagtc cctgatttac 480 aactctcttt cgaacatatt gcacgacgct ggcatgccag taataaacaa tgggcacaat 540 cacacagcga taaagtactc aaaagcctcg agacacacgt attccccttt atcggcaatc 600 gggatatcac aacactcaat accccggacc tgcttatccc tgttcgtgct gcagaagcta 660 aacaaattta tgaaatcgcc agtcgtctgc agcaaagaat atctgccgta atgcgttatg 720 ccgtacagtc tggcatcatc agatataatc ctgctctgga tatggctggc gcattgacta 780 cggtaaaacg ccagcatcgc cccgctcttg atctttctcg cctgcctgaa cttttgtcgc 840 gtattggcag ttacaagggg caacctgtca cccagcttgc cgttatgctg aatttactgg 900 tttttattcg ttccagtgaa ctcagatacg cccgctggtc tgaaattgat attgacaatg 960 ccatgtggac tattccagcc gaacgcgaac ctctgccagg cgtaaaattc tcacaccggg 1020 gatccaagat gcgaacacca catcttgtgc cactcagcaa acaggttgta gccatactgg 1080 cagaacttca gacatgggct ggtgaaaatg gtctgatctt tacgggagca catgacccac 1140 gtaaaccaat cagtgaaaac accgtaaata aagccctgag ggttatgggg tatgacacaa 1200 cccaggatgt ctgtggtcat ggattccggg cgatggcatg tagtgcgtta atagaatcag 1260 gtttgtggtc ccgcgatgca gttgaacgtc agatgagcca tcaggaacgt aacggtgtac 1320 gtgctgctta cattcataaa gcagaacatc tggaagaacg gcgactgatg ctacagtggt 1380 gggccgattt tctggatgca aacagagaaa gatttatcag tccatttgaa tatgcaaaga 1440 ttaataatcc attaaaacag taatcatccc gggcaaatgc ccgggaacct actccaggat 1500 tattttcttt gttaaaaaaa cagacaaaac ggtattagct tcgtaagcgt acagcgaggg 1560 ccgtattgac ggggatgtgt tattcagctg gcagtgctat gcgccacgga agcagttcgc 1620 tgacccggtt gaccggccag tctgctatga cgccaagcac atggcgaagg tagctttctg 1680 gatccacgtc attcagtttg cacatcccga tcaggctgta cagtagcgct ccccgctcac 1740 caccatggtc agagccgaag aacaggaagt ttttacgacc cagactgacc gcccgcaggg 1800 cattttcagc gatgttgttg tcgatttcca cccagccatc gttcgcatag tacgtcagtg 1860 ccggccactg gttaagtgcg tacgcgaacg ccttcgccaa ctctgagtgt cgcgacaggg 1920 tcttcatctt ttcacgcaac cagctttcca gggatttcaa cagcggtttc gtttttcgct 1980 gacgttcagc aagccgctgc tctgccggca ttccccttat atccgcctct atggcgtaca 2040 actgaccgat ctgctccagg gcttcttccg tcagtgctga cgggatgcgg acgtgcacat 2100 cgtggatctt tcggcgggca tgagcccagc aggcagcttc cgttatccca ccattgcgat 2160 acagctcgtt gaacccggcg tacgcatccg cttgcagcac actgtcacga acggtgcaat 2220 agtcatccgt cgttgacaac agctgatact gagggtttcc gggtcctctg cgagcgattc 2280 tggctgttcg gcagctgcat cgagagtcac aggaagtagc tgggggctct ctgaagaagg 2340 taatagcagc tttccctcgc gccattgttg tgtaagcgcc ccatctgcga cgtcttgtga 2400 aaattgtcct gtctggcaac aatcgcgccc atctatatag atggacacga acgatgaatt 2460 cccagacaaa aaaagatatt ccctgcttcc gttcttattt gcctgatgct ctgcgtttaa 2520 gatttgaaga taaactgacc atccgggcca tcgctcagcg tctaggtctc agtcattcca 2580 caatacatac gctttttcag cgatttattg catccggtat cgcatggcca ttgcccgatt 2640 cagtttcatt agctcagctt gacgccatcc tttatgccaa cagaaagaag gaattaacag 2700 agcctcaaat cagcgaaggc acatggcgaa aagaacgacg aacctcctac agtcgtgaat 2760 ttaaaatcag gctggtaaaa caggcattac agcccggtgc tgttgttgcc cggatcgcca 2820 gagagcacgg tatcaatgat aacctgctgt taaaatggaa aagccagtac gaggacggct 2880 tactgagcga tgatgacata caggaatgca tgcctgtccc ggtggctctg actgatacgc 2940 cagagccgac cagaccagtt acaaatccct tctggcgtaa caagcctgat gagtgccctg 3000 agagtgatcc cggaaacgtc ccacggtgcg agctgcatct taaatcaggt gtggtaaaac 3060 tgtttgaccc tctcactccg gaaatgttac gggcgctaat ccgcgaaatg aaaggaggta 3120 cccgatgata acgctgccaa ccggtaccag aatctggatc atcgctggca tcacagatat 3180 gcgttgtggc ttcaacggcc tggcttcgaa ggtgcagaac acgctgaaag atgccccgtt 3240 ctccgggcat atcttcgtct tccggggccg cagtggcaaa atggtgaaaa tactgtgggc 3300 cgatcgtgac gggttatgcc tgttcgccaa acgcctggaa cggggccgct tcgtctggcc 3360 ggtaacccgg gaagggaaag tgcacctgac gccagctcag ttatccatgc tactggaggg 3420 gatcgcatgg caacatccca aacggacaga acggcctggc atccggatat aacccgtgat 3480 aaaacagggg aatgaacaac acactccccg acaacatcga gcaactgaag gccctgctga 3540 tcgcacagca ggctgttatc gtccgtctgt ctggtgaaat aaccggctat gcccgcgaga 3600 tcagctcact cagagcgctg gtcgctaaac tgcagagaat gttgttcggt cgcagcagcg 3660 agaaaagccg cgagaagata gaaaagaaga tcgcacgggc agaaacgcgt ataaccgagc 3720 tccagaacag gcttggtgag gcgcagttgc aactcacctc aatggccgga gagacagcgc 3780 cgaaaacatc agactctccc gtccgcaaag cacttccggc aacacttccc cgtgacaggc 3840 aggttatctc cccggcagaa accgaatgcc ccgtctgcag cggtaaactg aaaccgctgg 3900 gagaaagcat ctctgaacaa ctggatatca tcaacaccgc gttcagggta atcgaaacgg 3960 ttcgcccaaa acgggcctgc agccggtgcg actgtatagt tcaggctccg cagccaccaa 4020 aacccatcga gcgcagttac gccagtccgg ctctgctggc ccgcataatc atggctaagt 4080 tcgccgagca tctgccgctg taccgtcagt cggaaatcta tgcccgccag ggcgtggagc 4140 tgcaccgcaa tacgatgggg cgctgggttg acatcatggg agagcagctt cgcccgctgt 4200 atgatgaact gaagcactat gtgctgatgc cgggtaaagt gcatgccgat gacacgccgg 4260 taaatgtact ggagccgggt cagggtaaaa cccgtaccgg acggctgtgg gtctatgttc 4320 gtgacgatcg caacgccggt tcgaccatgc cggcagcggt gtggttctca tactctcccg 4380 accgcaaagg catccaccca cagcaacatc tggcggacta cagaggtatc ctgcaggccg 4440 atgcatatgc gggttacaat gctctttacg aaagcggtca ggcaaccgaa gcggcttgta 4500 tggcacatgc ccgacgcaag atccacgatg tacatgtccg ccatccaacg acagtaacgg 4560 gagaagcgct ccgtcgtatc ggggaactgt acgctatcga ggctgagatc cgcggcagtc 4620 cggcagaaga gcgactggcg gtcagaaaag ccagaacggt accgctaatg cagtcgttgt 4680 atgagtggct ccaggggcag atgaacacgc tgtcgcgcca ctcggataca gcgaaagcgt 4740 tcacctatct gctgaagcaa tgggacgctc tgaacgaata ctgccgcaat ggctgggtgg 4800 agatcgacaa taacctgtgt gaaaacgccc tccgggtagt tgcactgggg cggcgtaact 4860 accggacgtg gtttctgcca ggtaaaggca acggaacaaa agaatcatgg tttttccgga 4920 accggccaca ccatgaatga cacgatgccc gtcaccaata tttctggcca gaatctcctg 4980 ctgaatatcc ataattttga tttgtgagtt ctgtttcacg gtcacttcag gaaacagatg 5040 ggcgcgcaga atatccctca tccggggtgt tacccgggtt ctgaaccccg tggtaaacat 5100 cccggcaatt ttttgccgga atacctcagg taaaacagac tgcgtcattt catcctgaca 5160 gattgtctgt gctgaaggaa aaatcttttc caccgcattc tcattattcc ctgtcagtgc 5220 cttcagttgc tgacgggtaa tgcgggtaaa caccacacca tacgcccagg ccaggttcag 5280 ccgcccctta tactgaccgt cattctgccg taagcacggg tcagcaggta aggcattaac 5340 cgtatcacag gcataacgac gaacctgtac cagcggattt atttctgatt tcagaagacc 5400 gtcggtttcc agtgtaacct gctcctgatt tgctttacgt aatgtggata cagtccagtc 5460 cttgacctcc agaaatacca gcccgttatc cgggtcaata atgacaaaat ccggatgtcg 5520 gtttttccgt cccaccggga tatcgtacca gacaaagcaa tcatcattca gaaagctctc 5580 cagtcgtgaa gccaccctcc tctcccctgg cgtcattctc tcctcagtgg acgctgatat 5640 atttatcagt ttcgccataa catactcatg ctccagtaaa accataaccg tcgacatatt 5700 ccgtctgaag ggaatatgtc gaatacttca ttaaaataca aacatttagt aaacttcact 5760 acgcaagtgc aattatccag tcccgtctaa tgattaaaaa cgataaccaa ctccaacagt 5820 aaatccattg accgaatgtt ttccatatat atctgcttta gttccctcat acccaacatt 5880 tacagacata ttgccccacg gattaataat aacaccagct gcataagcaa aatcagtgga 5940 tttttttgat acagactcac ttaaatatcc atcagactca tcagcaccca cactgtttct 6000 ccactcataa tctcccttcg ctttagtatg agatatcccc accaaaccat aaaaactgat 6060 atagtcattc agacgataag ctgggcctgc gagaaatgaa taatatttaa tatcagcctg 6120 atgtctgtaa aaatcgtcag cttcatcgcg atgactgtcc gcccaatcac ctttcatata 6180 cgaaaaactc ccgacgacac tgaccggaga atcccactca tatcgatatt gcagattcac 6240 tcctttaata ttcttaaagt cctgtacctt actctgagca taaccagccg atagcgtatg 6300 attatcagcc agtcttgaac cactcataac atataatatc attactgaaa ttataacgag 6360 tttttttcat ttaaccctcc ttcattaata aatgatttct gaaaatcaaa aaggaccaca 6420 catctcaaaa acattatttg aaatcatcat caaaaaacta taaatatatc acctgacgat 6480 ttgaacacac tgacaaaaaa ccaagcatgg taataaaccg aactccccac aaacttctgt 6540 tgcctcagat actccccccc ctttcctcag gcacaaatgt tgttccataa cgaaccagcc 6600 ctgttccttt aaactctgca tcaatggcat aatgtatact caccagactg agtttgctcc 6660 tgcatcatta tttcgatacg ttaatgcatt gttcattgca tccggcattc cccatcgaat 6720 atttactttg ttatatcagt cagcccataa ccaggtaaat ttttaaggct tactgactga 6780 atattcaaaa tgtgttacat gttatcaaac ctttaaagaa taacctgctc ttcttcattg 6840 gccggattta gctcaatctt gtcagcaaaa ctaatataaa gccgttcata aagagaagga 6900 tgtagcttcg ttatttatct tttacatgta acagtgccag gggatattcc gcacatctct 6960 gtggctatca tccccaccac gtctccagtg gcagcacctg cggcactggc acgggcgtta 7020 tttccctgta ccaccgccag tgcagcattc accacggcat gagctgccac atttgcagtc 7080 ttattcacca cacctgtaac ctgtctctta tacacaaatc cccacccggg gatttgtgat 7140 gtctgtcagt ctgctttagg gggactcttt ccatccggta gtttccttcc tccccggcag 7200 cgattttttg aactttttct tcacccgttg atcttctctt atatttcatt ttcttcgggt 7260 ctgttatggt actttctgat tgttattcac tggctaacga gcagtctgga catgcccgtc 7320 tcggtgatcc gcgtcgtaca cgacgccttg tgtcactgac ctcttctctc gctcagcatg 7380 caggtctttc tattgtgaaa tcatcccact tcactgctca ggttgaaggt gcgtaccgcc 7440 tgatacgtaa cccgtcggtg tccccgtaag ccattgccga agccggattt actgccactg 7500 caagggcatg tgaggcacat ccgctgctcc tcgcgctgga agataccacc accattaact 7560 tcggtcacag tacggcattt gatgacctgg ggaataccac cactaacccg aagacgcacg 7620 ggctgctggc tcactctgtc ctgatgtacg cccccgacag cgccctgcca gtcgatctta 7680 tcgaacagca gtgctggagt cgtgccacgg acacctacgg tgttaagcac cagcgaaaag 7740 aacgtccctg tgaagaaaaa gaaagttacc gctggcagca ggcttcggag cgcatggccg 7800 aacggctgag ggagatacag aaacaggtaa tcactgtctg tgaccgggaa gcggatatct 7860 ggcattacct gcattataaa gtcagccgcg ggaagccaca cgctgaatgt gatgcaaaaa 7920 ggcgggcggg cagcccgcca ggcccggatg ctcatcagtt acagcgaagt cagcataaaa 7980 aatcccgaca acagcggcca ggcgctctcg ctcacgtatg tctgttgcgg ggagcaggag 8040 aggacggagc ctgctggtat ccgctgacat cagaaaaagt ggcgagtgcc gccgatgcgc 8100 gacgtatcgt cagccattac gagcaacgct ggctgataga ggaataccac aaagcgtgga 8160 aaagtggtgg tacatgtgtg gaatcgctgc gaatgcagac ccgggataac cttgagcgca 8220 tggtggttat cgcggtgcgg gtgctgggcc tgcggcaggg aggtatcagt gaagaaacac 8280 aaaatgacag ctgtgagaaa atactgacgc cgacagagtg gaaactactg tgggttaagc 8340 tggaaggaaa gcagcttccg gcgcaaacac cgaccctgaa atgggcctgt ttgaaactgg 8400 ctaaactggg gcgatggcat gacagcaaac gcacaagcag ccccggttgg gtagttatgt 8460 gggatggctg gttcagacat caggatatgg ctgagggtta cctggtgatg aagtctcttg 8520 atcaggagat ctgatcaaga gacaggtcaa agatggggga caacgtctgg tgctgtataa 8580 cagcacaggc ctcacactct tgacgcccgt ggaatatatt agagaacaaa aatttcaata 8640 tgtggtggac gcatacagag gattgacagc attcccatac taattgttaa gattcaaatt 8700 gaagtatatc tatctgtcat tttgcaaatg atatgcggta gctttaccta actatcatga 8760 acatttcgaa aaatcatcca caaagccccg aagaataaag cactatcgcc cgataaagac 8820 ctgtaagctc agtggcatgg atactattga gctcagaatg gcgagctgta ccgttatttc 8880 attaccatgc tcgacgaaca cagcaactac tctctggccg tactatcgct taaaagtgat 8940 atcatcaggc atttcttctg ctgtgtagcc cagttgttcc ttgttggtat caaccagatc 9000 atcactgatg atgggcaaag agttctcggg aaaattcgac aaaacgctac aggaagccac 9060 cgtcgggttc gtatggactt atctctatac gccgaaaata aatgccataa gtgagcattt 9120 taaccgaaca ctgagggaac aatttattga gtttaatgaa gaattgctct ttgaatagct 9180 gaatatgttc aatctgaaac tggctgagta tctggtactg tacaacagta aaattcttca 9240 taaatcgttt aaactacaaa aatcagtaga atatattatt tccactgtca ggcggaaaat 9300 ttatagaaag gatacaaaca tatgccaata ataaacaaat cggcatcaaa ttatgttgaa 9360 tatatttcaa aaaacaatcc cccttattta tcaaaaaaga gagatgccag tataaatcta 9420 aatggaaagg ttagtgattg caatggggaa atcatatggt gtcgacatat agcatcatat 9480 tggagtgagt ttttttgtag taattcagga aagatagact acgaaacatt ttcatcccct 9540 caattattaa gcaaagctat tgtaattcag gaaaacaagg ggacaaataa tattaagggt 9600 gatgtgtatt ttgttgaaaa tgaatcttgg ggaagcgtta tatataacct ttttcttcaa 9660 cttgagaaag agaataaatc tcacacatca ttagaagttc attctcccgg acatgcaatg 9720 gctctgggca ttaaaataaa aaacgacaag gaaaataagt ttgttattaa tttctatgat 9780 cccaatcaga ccgcgacgca taaacgagta tttttttgca ctaataacat ttgtgatata 9840 ataaacctga cagcatatga ttttcttagt gagcaatgtc tgaaatgtta tgggctaaaa 9900 gaagacacac tgtcactttt tgtggataaa acaaaatcga atgacaacaa taatgtgttt 9960 ataaaaaaat tacctgataa tattctccaa ggtgttgtta ttaattttgc tatgggagca 1002 0 ggactaagag agataataaa aaaggtatat aacgatactc gatttacaga tcttacaaaa 1008 0 tctcagatga aaatcttgtg tgaatcaaaa aatgttaata atgttcctgg gttgctttta 1014 0 gctctacaaa atggacatga taatgtaatt gatgaatatg gtactttaat taaaaagtca 1020 0 aatcttaata aagaagaatt aatacatata ttatctgcaa gaactttgga tggaaccata 1026 0 cctggtttat atcaggccct tcaaaatgga catgctcaag ctattaagag ttatggtaac 1032 0 ttagttctgg atactattaa taaaaatata gatttagagt atttgctttc agcatttaaa 1038 0 tatgaggcac atagctctaa taaatatact cctggattat tttctgcatt tcaaaatggt 1044 0 catgcagacg caataaaggc atattgtggc gtacttggca atagtaattt gaaaagaggt 1050 0 gagataatca ggatgcttga ggcgagaaat tatgatggtg caccaggatt acttcttgcg 1056 0 tatcaaaatg gagatattaa tacgattcag tctttttttg actcactaat aatgttagat 1062 0 atatcaaagg attttatcga agagttattg actgcaaaac attatgattt tacggggtta 1068 0 tcattagcga tcagtcatag acatgatcat gttgtcaaat tatacggaaa gttatttaaa 1074 0 aaacttgata ccagtccata taaaatgtca attatcctag cattagcaat tgattgcgag 1080 0 agaaataatg caaacataat tattgatagt gagtacaagt caaataaggc agtaaaggaa 1086 0 tatgtagaaa ttttaaaaga attcaatata tgcccagaaa aggtagcaga atacctaagc 1092 0 gagttcagcg gaaaacattt cctcgatgta tataattatt attccaattg aaaaaaatat 1098 0 aaagtatcta tcacggcact ctcagttgag tatcacaggc acatgtattt tagccccctg 1104 0 agtctacaga caaccaatat tacttaaata agtgataatc ttaatgctgt tttttagaac 1110 0 agatgattga tatttttggg ccggagaaac gcagacaggc tttgttgaat aaatcgagct 1116 0 tttgctgagt ttaaggatca gatcactcat tttcctgcaa aagctcattg ggcgaaacaa 1122 0 tctgactcag agaacccgga ttaaacgtct ggcccgcaga atcatctatt tctcacgcac 1128 0 tgtagtacgt aataaaaaag tcatcggtac ttttatcaaa aaacatatat tctattaatt 1134 0 attgccatca cctttttctt attgacaaca ttactctgct gattgttaaa atctaacctg 1140 0 tattcagggt tacgattcta tacaatagaa cagggagggg aaaggatgtc atcgttaatg 1146 0 agactttttg ttaatgtcaa caatgctatg aatttatttt agaaaaacaa ttaagctgac 1152 0 gtagtgttcc gtctaaatga cggggcgata ttaacatgat tagaacaaga ggaattttat 1158 0 gttatcttca ttaaatgtcc ttcaatccag cttcagagga aagacagctt tatcaaatag 1164 0 tacacttctc cagaaagttt cttttgctgg aaaagaatat cctctggaac ctattgatga 1170 0 aaaaacccct attctttttc agtggtttga agcaaggcca gagcgatacg aaaaaggaga 1176 0 agtaccaata ttgaatacca aagaacatcc gtatttgagc aatattataa atgctgcaaa 1182 0 aatagaaaat gagcgtataa tcggtgtgct ggtagatgga aattttactt atgaacaaaa 1188 0 aaaggaattt ctcagtcttg aaaatgaata tcaaaatata aaaataatct accgagcaga 1194 0 tgtggatttc agcatgtatg ataaaaaact atctgatatt taccttgaaa atatccataa 1200 0 acaagaatca taccctgcca gtgagaggga taattatctg ttaggcttat taagagaaga 1206 0 gttaaaaaat atcccagaag gtaaggactc tttgattgag tcatatgcag aaaaaagaga 1212 0 acatacttgg tttgattttt tcaggaattt ggccatgttg aaggctggaa gtttgtttac 1218 0 agagacggga aaaactggat gccataacat atcgccctgt agcggatgta tatatcttga 1224 0 tgccgacatg attattaccg ataaattagg agtcctgtat gctcctgatg gtatcgctgt 1230 0 gcatgtagat tgtaatgatg agataaaaag tcttgaaaat ggtgcgatag ttgtcaatcg 1236 0 tagtaatcat ccagcattac ttgcaggcct cgatattatg aagagtaaag ttgacgctca 1242 0 tccatattat gatggtctag gaaagggtat caagcggcat tttaactatt catcgttaca 1248 0 cgattataat gctttttgtg attttattga atttaagcat gaaaatatta taccgaatac 1254 0 cagtatgtat acctgcagtt catggtaagt cttccggttg tggttgaaaa atatcgttct 1260 0 ttaggtatag attcagatga ttaatcctgt tactaatact cagggcgtgt cccctataaa 1266 0 tactaaatat gctgaacatg tggtgaaaaa tatttacccg gaaattaaac atgattactt 1272 0 taatgaatca cccaatatat atgataagaa gtatatatcc ggtataacca gaggagtagc 1278 0 tgaactaaaa caggaagaat ttgttaacga gaaagccaga cggttttctt atatgaagac 1284 0 tatgtattct gtatgtccag aagcgtttga acctatttcc agaaatgaag ccagtacacc 1290 0 ggaaggaagc tggctaacag ttatatccgg aaaacgccca atggggcagt tttctgtaga 1296 0 tagtttatac aatcctgatt tacatgcatt atgtgagctt ccggacattt gttgtaagat 1302 0 cttccctaaa gaaaataatg attttttata catagttgtt gtgtacagaa atgacagccc 1308 0 tctaggagaa caacgggcaa atagatttat agaattatat aatataaaaa gagatatcat 1314 0 gcaggaatta aattatgagt taccagagtt aaaggcagta aaatctgaaa tgattatcgc 1320 0 acgtgaaatg ggagaaatct ttagctacat gcctggggaa atagacagtt atatgaaata 1326 0 cataaataat aaactttcta aaattgagta gagaagctca gccacttgtg taggggggct 1332 0 aaaattaatt ctatttcatt atatgagaac accaataaga ataataatat ttgatcacaa 1338 0 ctgaagatgc tttttacaat gaagaattat tgttaaaaaa cgctttgttg aatcaaccga 1344 0 actgttgctg agttgcagga tcacatcacg tattttcctg aaaacgcagg ctgcttagta 1350 0 gcaaagcaga agttcaaaat caccaactaa atagctgcgc cgaatagtag atcaatgaaa 1356 0 gggaactcag cccggattgt gcgatctgat caatcgccaa aaatcccccc ctaaccggac 1362 0 tgagcgatgc cgatcatagc accaattccc cgcgacgaat gacgcctgat gcaaaaagca 1368 0 atctataaaa ctcacgataa aaattatgcc cgcaggctga ccgccatgct gatgctgcac 1374 0 cggagcgctc gcgtcagtga cgttgccaga acgctctgct gcgcccgttc ctccgtcagg 1380 0 cgctggatta actggttcac gctgtcgagt gttgaaggtc tgaaatcatt acccgcagga 1386 0 cgttcccgcc gctggccgtt tgagcatatc tgcacattgt ttcgtgaact gataaaacac 1392 0 tctcccggat attttggcta tcagcgttca cgctggagta cagaactgct ggcaataaaa 1398 0 atcaacgaga taaccgagtg ccagttacat gccggaaccg ttcgccgctg gttgccatta 1404 0 gtcgggcttg tgtggcgcag ggctgcgcca accctgcgta cccgtaaccc gcataaagca 1410 0 gcaattcaca aagcactgga cgaatgtagt gcggagcatc cggtctttta tgaagatgaa 1416 0 gtgtatatct atcttaatcc caaaaccggt gcggactggc aacttcgcag acagcaaaaa 1422 0 catgtggtaa caccggggca gaatgaaaaa tactatctgg ctggtgcttt acatagtgga 1428 0 acgggcaaag tcagctatgt gggtggcaac agcaaaagct cagccttatt tatcagtctg 1434 0 ttgaaacatc tgaaattgac ataccgacgg gataaaccta tcacgctcat agtggacaac 1440 0 tacatcatcc ataaaagtcg ggaaacacag cgctggctga aagaaaatcc gaagttcaga 1446 0 gtgatttatc agccagttta ctcgccgtgg gtgaatcatg ttgagcggtt atagcaggcg 1452 0 cttcacgata cgataacgcg caatcatcag tgccgttcaa tgtggtaact gcttaaaaat 1458 0 gttcattatt ttatggaaac cgtgagccca ttccccggtg gtaaatatgg gctgttaaaa 1464 0 gtgtagcggt attcggcgca gctatttagg atggtcaggt cgcagaagtt ctgtgccact 1470 0 acagtgcgtg tactaaacaa aatgacgagg gcacgaatgt cataatacgt gcgtattacc 1476 0 tgacagtagc taccaactga gggggcttat tccaaacctg atttattcaa caaagctgga 1482 0 cttatcctta ctctgaatta ttttccagac atatgcatca tgtactggct cgcttggttc 1488 0 aggaaataca ggagcaaatc tacagctatt agatttattc ctatttgtat gcaaagtcgc 1494 0 attgcataat gcggagctat gttacagata cgcctgacgt gcgtagtaaa attataaagc 1500 0 aacatatata tacaaggaga aaccgagaaa aataaatgag tcgtatgttg ggtagcatcg 1506 0 agataaatat tttttttatc acattagcac cttggttaag ggtgttaata ataatattct 1512 0 ctcacttatt aaaacataaa taatttttta agcggaaatg taattatgag actgccagag 1518 0 aaagttcttt ttcctcctgt cactagtggc ctgtcagggc aggaaaaaca aaaaaaaccg 1524 0 aagagcatta ccggatttca ggaaaattat caacgcaata tcaggccaat caaaacagca 1530 0 tcagaagccc gactacgctt ctttgataaa atggtttcga aagaaaactc tctggaagat 1536 0 gttgtttctt taggtgaaat gattcagaag gaaatttatg ggcatgaaca aagaacattt 1542 0 tcaccagttc atcatacagg taactggaaa tcatcattgt tacacaacgc gctccttggt 1548 0 ctggcaaatg tttataatgg cttacgggaa acagaatacc ctaacacttt caacagagat 1554 0 ggtataaaaa gtactaactc ttttagagat aacttattga caaaaacaag aactcccaga 1560 0 gataattttg aggaaggaat aaaacatcct gaacatgcaa caataccata tgacaacgac 1566 0 aatgaaagta ataaattgct aaaagcagga aagatagctg gtaacaataa cgagctgttg 1572 0 atggaaataa aaaaggaatc ccaaagcgac catcaaatcc ccctgtcaga taagttcctg 1578 0 aaaaggaaaa aacgatctcc tgtagctgaa gataaagttc aaaactcgtt aacaccagaa 1584 0 aattttgttc agaaaatttc acttagtgat gagcttaaaa caaaatatgc aaatgaaatt 1590 0 ctagagataa aaagaataat gggagaatac aatcttttac cggataaaaa cagtcgtaat 1596 0 ggtctaaaac ttctacagaa gcaagctgat ttactaaaaa taatcatgga ggatacctct 1602 0 gttacagaaa atacctttaa aaacatagag atggctatag cagatataaa aagggagtac 1608 0 tattcgcata cagttgatat tgagaaaaat attcatgcca tatgggttgc gggttcccca 1614 0 cctgaaagca tctcggacta tattaagact tttctcaaaa cctacaaaga gtttacttac 1620 0 tatctttggg ttgatgaaaa agcatttgga gccgcgaaat ttaccagtgt cttaaaacaa 1626 0 attgcatttg atttagcatg cagaactata cagcagaata ctccacaaaa aaatattgat 1632 0 tttattaatc tatataatga aataaggaag aaatacaaca acaacccatc gggacaacaa 1638 0 gagtacttaa acaaactcag agagctttat gctacttatc aaaaaatatc cacccctctg 1644 0 aaacacatgt ttaattcatt tttttagaaa acatgattaa acttcaggat aatttcttca 1650 0 actattgcat tgtcaaaggt gttacagaga ttaatgatga gttacgaata aactacctta 1656 0 aaaatgtaat aaaactgtca gacgatgaca ttggtaatta tcagaaaaca attaacgaca 1662 0 ataaagatag agtaaaaaaa ctaattcttg atttacagaa acaatttggt gaaaaccgca 1668 0 tttcaattaa agatgttaac tctttaacct ctctttcaaa atcagaaaat aatcacaatt 1674 0 atcaaactga aatgttgctt cgatggaact atcctgccgc ctcagacctg ctcaggatgt 1680 0 atatccttaa agagcatggt ggtatttata cagacacaga tatgatgcct gcatactcta 1686 0 aacaagtaat ttttaaaatt atgatgcaga caaacggaga taatcgtttc ttggaagatt 1692 0 tgaaactacg tcgtgcaata tctgatggtg tattaagata tgttaataac caaaatattg 1698 0 atgaagttaa ctataatgaa atcagtgatg cagataaaaa cattatcaag aagatattaa 1704 0 cagaaatatc taaaatgcca gaagatagta tttttactaa gatcaataca aggattcctc 1710 0 gagacacaat gcccatcctt cgtcgttatc acctatggcc tgatggatgg aatattcgtg 1716 0 ggctcaatgg attcatgcta tcacataaag gtagtgaagt gattgatgct gttatcgcag 1722 0 gccagaatca ggcttacagg gaactaagaa gaataagaga taatattcat agtgaaatat 1728 0 acttcaaaca aactgattga accgccccgg ttttcctgga gagtgtttta tctgtgaact 1734 0 caggctgcca gatcatcgtt tccgatggaa gcataataag ctttttctgc ttctgccgga 1740 0 ggagtatggc ccagccttcc cagcaatcgt cgattgttat accagtccac ccacgttagt 1746 0 gtggccagtt ccacttctgc acggtttttc cagctcttac ggtgtattac ctccgctttg 1752 0 taaagaccat tgatgctctc agccatcgcg ttgtcatacg agtcgcctgt actccctgtt 1758 0 gatgccagta atccggcttc ttttagtcgc tccgtatagg ccagtgacac atactgagag 1764 0 cctttatcgc tgtgatggat ggtgccagac ggacgacggg cccacaacgc ctgctccagc 1770 0 gcatccagca cgaatgtcgt ttccatagac gatgagaccc gccaccccac gatgtatccg 1776 0 gcaaacacat caatgataaa cgccacatag acgaagccct gccatgtgct gacgtaagta 1782 0 aaatcagcca cccacagctg gtcaggtcgt tctgccacga actgacggtt tacgcggtcg 1788 0 cctgcggcaa cggctttccg gctgatggtc gtacggacct ttttaccccg gagaacaccg 1794 0 gcaagtccca taaccgccat gagacgtgcc actgtacatc tggccaccct gattccttcc 1800 0 cgtaacaact gacgccagac tttacgcaca ccgtacacct gatgattttc atcgtatacg 1806 0 cgctgtatct ctctcttcag ccagtcgtcg tgctgcgcac gggcactgcg tttatccgga 1812 0 tgatgtcgct gttgctgaca atggtaatac gttgacgggg caatatgcag ttcgctgcat 1818 0 accggtccga ccccgtactg ctcacgcagc ttatccagca gtggcatcat tttttccaga 1824 0 ggcggtcgaa ctccgccttc gcaaaataag cggaagcctg gcgaaggata tcgttactgc 1830 0 ggcgcagttc acgattttca cgttccagct ctttcagacg ctgacgttca gcgctggtga 1836 0 gcccaccatc accgcccccg gtatcccgct catgctggcg aacccagaca cgcagagtct 1842 0 ccggcgtaca gccaatcttt ggggcaatgg aacaaattgc cgcccactgt gagtcatatt 1848 0 catcctgact ttccagaacc atacgaatcg cccgctgacg gacttcgggg gaaaaacgag 1854 0 tatttttagt catcctgttt acctctttct cagggagttt agtctccagg atttccgggg 1860 0 cggttcacac agccagaatc gctcgcagag gacccggaaa ccctcagtat cagctgtgag 1866 0 gtaacgttcc ggcacgggac gctccgcttc aatggcaatg tcagcgaaaa gctcctgact 1872 0 ctgctgatac aggaactgaa gcgatgatcc cgttaccttc cgggaccaaa atttggctgg 1878 0 ttgccggtat caccgatatg agaaatggct tcaacggcct ggctgcgaaa gtacaaacgg 1884 0 cgctgaaaga cgatcccatg tccggccatg ttttcatttt ccggggccgc agcggcagtc 1890 0 aggttaaact gctgtggtcc accggtgacg gactgtgcct cctgaccaaa cggctggagc 1896 0 gtgggcgctt cgcctggccg tcagcccgtt atggcaaagt gttccttacg caggcgcagc 1902 0 tggcgatgct gctggaaggt atcgactggc gacagcctaa gcggctgctg acctccctga 1908 0 ccatgctgta aatctcttta tcctggttgt cacagaataa gcccggtaaa atacgggctt 1914 0 atgaacgaca tctcttctga cgacatcttc ctgctgaaac agcgcctggc cgaacaggaa 1920 0 gcgctgatcc acgccctgca ggaaaagctg agcaaccggg agcgcgaaat agaccatctg 1926 0 caggcgcagc tggataaact ccgccggatg aacttcggca gtcgttccga aaaagtctcc 1932 0 cgccgtatcg cacaaatgga agccgatctg aaccggcttc agaaagagag cgatacgctg 1938 0 actggtaggg tgtatgaccc ggcagtacag cgtccgttgc gtcagacccg cacccgtaag 1944 0 ccgttccctg aatcactacc ccgtgacgaa aagcgactgt tgcctgcggc gccgtgctgc 1950 0 ccgaactgcg gcggttcact gagctatctg ggcgaggata ccgccgaaca gctggagttg 1956 0 atgcgtagcg ccttccgggt tatccggacg gtacgggaaa aacatgcctg tactcagtgc 1962 0 gatgccatcg tgcaggcacc tgcaccttcg cggcccatcg agcggggtat cgccggaccg 1968 0 gggctgctgg cccgcgtgct gacctcgaag tatgcagagc acaccccgct gtatcgccag 1974 0 tcagaaatat acggccggca aggtgtggag ctgaggcgtt cactgctgtc gggctgggtg 1980 0 gatgcatgct gccggctgct gtctccgctg gaagaggcgc ttcatggcta tgtcatgact 1986 0 gacggcaaac tccatgccga tgataccccg gtccaggtac tgctgccggg taataagaag 1992 0 acgaagaccg ggcggttgtg ggcgtatgtt cgtgatgacc gcaatgcagg gtcagcgttg 1998 0 gcacctgcag tgtggttcgc ttacagcccg gacagaaaag gcatccatcc gcagactcat 2004 0 cttgcctgct tcagcggtgt gctgcaagcg gatgcgtacg ccgggttcaa cgagctgtat 2010 0 cgcaatggtg ggataacgga agctgcctgc tgggctcatg cccgccgaaa gatccacgat 2016 0 gtgcacgtcc gcatcccgtc agcactgacg gaagaagccc tggagcagat cggtcagttg 2022 0 tacgccatag aggcggatat aaggggaatg ccggcagagc agcggcttgc tgaacgtcag 2028 0 cgaaaaacga aaccgttgtt gaaatccctg gaaagctggt tgcgtgaaaa gatgaagacc 2034 0 ctgtcgcgac actcagagtt ggcgaaggcg ttcgcgtacg cacttaacca gtggccggca 2040 0 ctgacgtact atgcgaacga tggctgggtg gaaatcgaca acaacatcgc tgaaaatgcc 2046 0 ctgcgggcgg tcagtctggg tcgtaaaaac ttcctgttct tcggctctga tcatggtggt 2052 0 gagcggggag cgctactgta cagcctgatc gggacgtgca aactgaatga cgtggatcca 2058 0 gaaagctacc ttcgccatgt gcttggcgtc atagcagact ggccggtcaa ccgggtcagc 2064 0 gaactgcttc cgtggcgcat agcactgcca gctgaataac acatccccgt caatacggcc 2070 0 ctcgctgtac gcttacgaaa taacgccgga tgagcagaaa gaacctgtgg cggccattgc 2076 0 gccgtcttta tccacttcca ctcagaccag agtcagtgcc agttcctgca aggtggaatt 2082 0 ccgtcacggt aacatgacgc tggaaaatcc atcgccagag ctgctcacga tgttaatccg 2088 0 cgaactgagc gggaggggaa gatgatttca ctcccatcag gtacccgtat ctggctcgtt 2094 0 gccggcgtta ccgatatgtg taaatccttc aacggactgg gagaacaggt acaacatgtg 2100 0 ctgaatgata atcccttctc cggtcacctg tttatcttcc gtggccgacg gggggacacc 2106 0 gttaaaattc tttgggctga tgctgatggt ctgtgcctgt tcaccaaacg cctggaggaa 2112 0 ggccagttta tctggcctgc ggtgcgtgac ggtaaggtat ccattacccg ctcgcaactg 2118 0 gcaatgctcc tcgataagct ggactggcgt cagccaaaaa catcccgcct taacgccctg 2124 0 acaatgttgt aaaaaacacc tggccgcatt ataaaaacgg ccatgagtca gaaatacctc 2130 0 attcgcattg cagaactgga aagccagctc cgtcagaaag accagcaact gagtctggtt 2136 0 gaagagacgg aggccttcct gcactggcac gtgccgaaga aaagatcgaa gaagatgaac 2142 0 gggaaataga acatctgcgg gctcagatag aaaaactgcg ccggatgctg ttcggtaccc 2148 0 gttctgaaaa actgcgtcgt gaagttgaac aggctgaggc cctgctgaaa caacgcgaac 2154 0 aggacagcga tcgttacagt gggcgggaag acgatccaca ggttccccgc cagttgcgac 2160 0 agtcgcgcca tcgtcgtccg ttaccggcac accttccccg tgaaatacag cgtctggaat 2166 0 ctgaagaaag ctgttgcccg gagtgtggcg gtgagctgga ttatctgggg gaagtcagtg 2172 0 cagaacaact ggaactggtg agcagcgccc tgaaagtgat ccgcacagaa cgggtaaaaa 2178 0 aagcgtgtac aaaatgtgac tgcatcgttg aagcaccggc gccgtcccgc ccgatagagc 2184 0 gtggtatcgc gggccccgga ttacttgccc gcgtgttaac gggaaaatac tgcgaacacc 2190 0 tgccactgta tcgtcagagt gaaatctttg cccgacaggg tgtcgaactg agccgtgcat 2196 0 tactctccaa ctgggttgac gcgtgctgcc agttaatgac gccgctgaat gatgccctgt 2202 0 accgttatgt gatgaatacc cgcaagcttc acactgacga cacaccggta aaggtactgg 2208 0 caccgggcct gaaaaagacg aaaacagggc gcatctggac gtatgtccgg gatgatcgca 2214 0 atgcgggttc gtcatctcct ccggcggtct ggttcgcgta ctcaccgaac cggcagggga 2220 0 aacacccgga gcaacacctc cgccccttcc ggggtatcct gcaggcggat gcgttcacag 2226 0 gttatgacag gctgttcagt gcagaacgtg aaggtggtgc gctgacagaa gttgcgtgcc 2232 0 gggcccatgc ccggagaaaa atccacgatg tatacatcag cagcaaaagt gcgacggcag 2238 0 aagaagccct gaagcgaatc agtgaactgt acgccatcga ggatgaaata cggggattac 2244 0 cagagtcaga gcgtcttgca gtcagacagc agcgaagcaa agcgttactg acgtcgctgc 2250 0 atgaatggat gatggagaag aatggcacgc tgtcgaaaaa atccagactg ggcgaagcgt 2256 0 tcagctatgt actgaatcag tgggacgccc tctgttatta cagtgatgac ggactggcgg 2262 0 agacggacaa taacacagcg gaaagagcgc ttcgtgcagt ctgtcttgga aagaaaaatt 2268 0 acgtgttctt cggtagcgat cacggcggcg agcgtggtgc actgctatac gggctgatcg 2274 0 gcacctgccg tctgaacggt atcgatccgg aagcgtatct gcgccatatt ctgagcgtac 2280 0 tgccggaatg gccctccaac cgggttgatg aactcctgcc atggaacgta gtactcacca 2286 0 ataaataagc gtcaatacgg tgctccgttg acgcttacct tctttcattc gctgaaggtg 2292 0 gaatgtatcc acggggaacg ctttagcagc cgggaaataa tgcgggaaac ggtgtttaat 2298 0 tatatcgagt gtgattacaa tcgctggcgt cgtcacagtg cctgtggcgg tctcagcccg 2304 0 gactgtcttg cactgcaaat attcagaaat gagtctatgc agttcaccag taaaatcagc 2310 0 catcagagag ggaatgtagt ggcacagtaa atttggccac ctgattaaag gtgatatcct 2316 0 caccacaaca caaaacaggt gacttaatga acaagaaaac caaacgtact ttcacccctg 2322 0 aattcaggct ggaatgtgca cagctaattg ttgataaggg ctactcatat cgacaagcca 2328 0 gtgaagcgat gaatgtcggt tctaccacgc ttgagagttg ggtgcgccag ctcaggcgag 2334 0 agcgtcaggg gattgcgccc tctgccacac ctattactcc agaccagcaa cgtatccgcg 2340 0 aactggaaaa gcaggttcgc cgcctggagg aacacaatac gatattaaaa aagg 2345 4 <210> 1129 <211> 422 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(198..1463) <400> 1129 Met Ala Leu Thr Asp Ala Lys Ile Arg Ala Ala Lys Pro Thr Asp Lys 1 5 10 15 Ala Tyr Lys Leu Thr Asp Gly Ala Gly Met Phe Leu Leu Val His Pro 20 25 30 Asn Gly Ser Arg Tyr Trp Arg Leu Arg Tyr Arg Ile Leu Gly Lys Glu 35 40 45 Lys Thr Leu Ala Leu Val Val Tyr Pro Glu Val Ser Leu Ser Glu Ala 50 55 60 Arg Thr Lys Arg Asp Glu Ala Arg Lys Leu Ile Ser Glu Gly Val Asp 65 70 75 80 Pro Cys Glu Gln Lys Arg Ala Lys Lys Val Val Pro Asp Leu Gln Leu 85 90 95 Ser Phe Glu His Ile Ala Arg Arg Trp His Ala Ser Asn Lys Gln Trp 100 105 110 Ala Gln Ser His Ser Asp Lys Val Leu Lys Ser Leu Glu Thr His Val 115 120 125 Phe Pro Phe Ile Gly Asn Arg Asp Ile Thr Thr Leu Asn Thr Pro Asp 130 135 140 Leu Leu Ile Pro Val Arg Ala Ala Glu Ala Lys Gln Ile Tyr Glu Ile 145 150 155 160 Ala Ser Arg Leu Gln Gln Arg Ile Ser Ala Val Met Arg Tyr Ala Val 165 170 175 Gln Ser Gly Ile Ile Arg Tyr Asn Pro Ala Leu Asp Met Ala Gly Ala 180 185 190 Leu Thr Thr Val Lys Arg Gln His Arg Pro Ala Leu Asp Leu Ser Arg 195 200 205 Leu Pro Glu Leu Leu Ser Arg Ile Gly Ser Tyr Lys Gly Gln Pro Val 210 215 220 Thr Gln Leu Ala Val Met Leu Asn Leu Leu Val Phe Ile Arg Ser Ser 225 230 235 240 Glu Leu Arg Tyr Ala Arg Trp Ser Glu Ile Asp Ile Asp Asn Ala Met 245 250 255 Trp Thr Ile Pro Ala Glu Arg Glu Pro Leu Pro Gly Val Lys Phe Ser 260 265 270 His Arg Gly Ser Lys Met Arg Thr Pro His Leu Val Pro Leu Ser Lys 275 280 285 Gln Val Val Ala Ile Leu Ala Glu Leu Gln Thr Trp Ala Gly Glu Asn 290 295 300 Gly Leu Ile Phe Thr Gly Ala His Asp Pro Arg Lys Pro Ile Ser Glu 305 310 315 320 Asn Thr Val Asn Lys Ala Leu Arg Val Met Gly Tyr Asp Thr Thr Gln 325 330 335 Asp Val Cys Gly His Gly Phe Arg Ala Met Ala Cys Ser Ala Leu Ile 340 345 350 Glu Ser Gly Leu Trp Ser Arg Asp Ala Val Glu Arg Gln Met Ser His 355 360 365 Gln Glu Arg Asn Gly Val Arg Ala Ala Tyr Ile His Lys Ala Glu His 370 375 380 Leu Glu Glu Arg Arg Leu Met Leu Gln Trp Trp Ala Asp Phe Leu Asp 385 390 395 400 Ala Asn Arg Glu Arg Phe Ile Ser Pro Phe Glu Tyr Ala Lys Ile Asn 405 410 415 Asn Pro Leu Lys Gln * 420 <210> 1130 <211> 207 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1580..2200) <400> 1130 Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr Arg Asn 1 5 10 15 Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg Lys Ile 20 25 30 His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu Ala Leu 35 40 45 Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg Gly Met 50 55 60 Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys Pro Leu 65 70 75 80 Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr Leu Ser 85 90 95 Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn Gln Trp 100 105 110 Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile Asp Asn 115 120 125 Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg Lys Asn 130 135 140 Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala Leu Leu 145 150 155 160 Tyr Ser Leu Ile Gly Met Cys Lys Leu Asn Asp Val Asp Pro Glu Ser 165 170 175 Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val Asn Arg 180 185 190 Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu * 195 200 205 <210> 1131 <211> 102 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2143..2448) <400> 1131 Val Ser Ile Tyr Ile Asp Gly Arg Asp Cys Cys Gln Thr Gly Gln Phe 1 5 10 15 Ser Gln Asp Val Ala Asp Gly Ala Leu Thr Gln Gln Trp Arg Glu Gly 20 25 30 Lys Leu Leu Leu Pro Ser Ser Glu Ser Pro Gln Leu Leu Pro Val Thr 35 40 45 Leu Asp Ala Ala Ala Glu Gln Pro Glu Ser Leu Ala Glu Asp Pro Glu 50 55 60 Thr Leu Ser Ile Ser Cys Cys Gln Arg Arg Met Thr Ile Ala Pro Phe 65 70 75 80 Val Thr Val Cys Cys Lys Arg Met Arg Thr Pro Gly Ser Thr Ser Cys 85 90 95 Ile Ala Met Val Gly * 100 <210> 1132 <211> 225 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2454..3128) <400> 1132 Met Asn Ser Gln Thr Lys Lys Asp Ile Pro Cys Phe Arg Ser Tyr Leu 1 5 10 15 Pro Asp Ala Leu Arg Leu Arg Phe Glu Asp Lys Leu Thr Ile Arg Ala 20 25 30 Ile Ala Gln Arg Leu Gly Leu Ser His Ser Thr Ile His Thr Leu Phe 35 40 45 Gln Arg Phe Ile Ala Ser Gly Ile Ala Trp Pro Leu Pro Asp Ser Val 50 55 60 Ser Leu Ala Gln Leu Asp Ala Ile Leu Tyr Ala Asn Arg Lys Lys Glu 65 70 75 80 Leu Thr Glu Pro Gln Ile Ser Glu Gly Thr Trp Arg Lys Glu Arg Arg 85 90 95 Thr Ser Tyr Ser Arg Glu Phe Lys Ile Arg Leu Val Lys Gln Ala Leu 100 105 110 Gln Pro Gly Ala Val Val Ala Arg Ile Ala Arg Glu His Gly Ile Asn 115 120 125 Asp Asn Leu Leu Leu Lys Trp Lys Ser Gln Tyr Glu Asp Gly Leu Leu 130 135 140 Ser Asp Asp Asp Ile Gln Glu Cys Met Pro Val Pro Val Ala Leu Thr 145 150 155 160 Asp Thr Pro Glu Pro Thr Arg Pro Val Thr Asn Pro Phe Trp Arg Asn 165 170 175 Lys Pro Asp Glu Cys Pro Glu Ser Asp Pro Gly Asn Val Pro Arg Cys 180 185 190 Glu Leu His Leu Lys Ser Gly Val Val Lys Leu Phe Asp Pro Leu Thr 195 200 205 Pro Glu Met Leu Arg Ala Leu Ile Arg Glu Met Lys Gly Gly Thr Arg 210 215 220 * <210> 1133 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3125..3472) <400> 1133 Met Ile Thr Leu Pro Thr Gly Thr Arg Ile Trp Ile Ile Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Cys Gly Phe Asn Gly Leu Ala Ser Lys Val Gln Asn 20 25 30 Thr Leu Lys Asp Ala Pro Phe Ser Gly His Ile Phe Val Phe Arg Gly 35 40 45 Arg Ser Gly Lys Met Val Lys Ile Leu Trp Ala Asp Arg Asp Gly Leu 50 55 60 Cys Leu Phe Ala Lys Arg Leu Glu Arg Gly Arg Phe Val Trp Pro Val 65 70 75 80 Thr Arg Glu Gly Lys Val His Leu Thr Pro Ala Gln Leu Ser Met Leu 85 90 95 Leu Glu Gly Ile Ala Trp Gln His Pro Lys Arg Thr Glu Arg Pro Gly 100 105 110 Ile Arg Ile * 115 <210> 1134 <211> 483 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3492..4940) <400> 1134 Met Asn Asn Thr Leu Pro Asp Asn Ile Glu Gln Leu Lys Ala Leu Leu 1 5 10 15 Ile Ala Gln Gln Ala Val Ile Val Arg Leu Ser Gly Glu Ile Thr Gly 20 25 30 Tyr Ala Arg Glu Ile Ser Ser Leu Arg Ala Leu Val Ala Lys Leu Gln 35 40 45 Arg Met Leu Phe Gly Arg Ser Ser Glu Lys Ser Arg Glu Lys Ile Glu 50 55 60 Lys Lys Ile Ala Arg Ala Glu Thr Arg Ile Thr Glu Leu Gln Asn Arg 65 70 75 80 Leu Gly Glu Ala Gln Leu Gln Leu Thr Ser Met Ala Gly Glu Thr Ala 85 90 95 Pro Lys Thr Ser Asp Ser Pro Val Arg Lys Ala Leu Pro Ala Thr Leu 100 105 110 Pro Arg Asp Arg Gln Val Ile Ser Pro Ala Glu Thr Glu Cys Pro Val 115 120 125 Cys Ser Gly Lys Leu Lys Pro Leu Gly Glu Ser Ile Ser Glu Gln Leu 130 135 140 Asp Ile Ile Asn Thr Ala Phe Arg Val Ile Glu Thr Val Arg Pro Lys 145 150 155 160 Arg Ala Cys Ser Arg Cys Asp Cys Ile Val Gln Ala Pro Gln Pro Pro 165 170 175 Lys Pro Ile Glu Arg Ser Tyr Ala Ser Pro Ala Leu Leu Ala Arg Ile 180 185 190 Ile Met Ala Lys Phe Ala Glu His Leu Pro Leu Tyr Arg Gln Ser Glu 195 200 205 Ile Tyr Ala Arg Gln Gly Val Glu Leu His Arg Asn Thr Met Gly Arg 210 215 220 Trp Val Asp Ile Met Gly Glu Gln Leu Arg Pro Leu Tyr Asp Glu Leu 225 230 235 240 Lys His Tyr Val Leu Met Pro Gly Lys Val His Ala Asp Asp Thr Pro 245 250 255 Val Asn Val Leu Glu Pro Gly Gln Gly Lys Thr Arg Thr Gly Arg Leu 260 265 270 Trp Val Tyr Val Arg Asp Asp Arg Asn Ala Gly Ser Thr Met Pro Ala 275 280 285 Ala Val Trp Phe Ser Tyr Ser Pro Asp Arg Lys Gly Ile His Pro Gln 290 295 300 Gln His Leu Ala Asp Tyr Arg Gly Ile Leu Gln Ala Asp Ala Tyr Ala 305 310 315 320 Gly Tyr Asn Ala Leu Tyr Glu Ser Gly Gln Ala Thr Glu Ala Ala Cys 325 330 335 Met Ala His Ala Arg Arg Lys Ile His Asp Val His Val Arg His Pro 340 345 350 Thr Thr Val Thr Gly Glu Ala Leu Arg Arg Ile Gly Glu Leu Tyr Ala 355 360 365 Ile Glu Ala Glu Ile Arg Gly Ser Pro Ala Glu Glu Arg Leu Ala Val 370 375 380 Arg Lys Ala Arg Thr Val Pro Leu Met Gln Ser Leu Tyr Glu Trp Leu 385 390 395 400 Gln Gly Gln Met Asn Thr Leu Ser Arg His Ser Asp Thr Ala Lys Ala 405 410 415 Phe Thr Tyr Leu Leu Lys Gln Trp Asp Ala Leu Asn Glu Tyr Cys Arg 420 425 430 Asn Gly Trp Val Glu Ile Asp Asn Asn Leu Cys Glu Asn Ala Leu Arg 435 440 445 Val Val Ala Leu Gly Arg Arg Asn Tyr Arg Thr Trp Phe Leu Pro Gly 450 455 460 Lys Gly Asn Gly Thr Lys Glu Ser Trp Phe Phe Arg Asn Arg Pro His 465 470 475 480 His Glu * <210> 1135 <211> 315 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4741..5685) <400> 1135 Met Val Leu Leu Glu His Glu Tyr Val Met Ala Lys Leu Ile Asn Ile 1 5 10 15 Ser Ala Ser Thr Glu Glu Arg Met Thr Pro Gly Glu Arg Arg Val Ala 20 25 30 Ser Arg Leu Glu Ser Phe Leu Asn Asp Asp Cys Phe Val Trp Tyr Asp 35 40 45 Ile Pro Val Gly Arg Lys Asn Arg His Pro Asp Phe Val Ile Ile Asp 50 55 60 Pro Asp Asn Gly Leu Val Phe Leu Glu Val Lys Asp Trp Thr Val Ser 65 70 75 80 Thr Leu Arg Lys Ala Asn Gln Glu Gln Val Thr Leu Glu Thr Asp Gly 85 90 95 Leu Leu Lys Ser Glu Ile Asn Pro Leu Val Gln Val Arg Arg Tyr Ala 100 105 110 Cys Asp Thr Val Asn Ala Leu Pro Ala Asp Pro Cys Leu Arg Gln Asn 115 120 125 Asp Gly Gln Tyr Lys Gly Arg Leu Asn Leu Ala Trp Ala Tyr Gly Val 130 135 140 Val Phe Thr Arg Ile Thr Arg Gln Gln Leu Lys Ala Leu Thr Gly Asn 145 150 155 160 Asn Glu Asn Ala Val Glu Lys Ile Phe Pro Ser Ala Gln Thr Ile Cys 165 170 175 Gln Asp Glu Met Thr Gln Ser Val Leu Pro Glu Val Phe Arg Gln Lys 180 185 190 Ile Ala Gly Met Phe Thr Thr Gly Phe Arg Thr Arg Val Thr Pro Arg 195 200 205 Met Arg Asp Ile Leu Arg Ala His Leu Phe Pro Glu Val Thr Val Lys 210 215 220 Gln Asn Ser Gln Ile Lys Ile Met Asp Ile Gln Gln Glu Ile Leu Ala 225 230 235 240 Arg Asn Ile Gly Asp Gly His Arg Val Ile His Gly Val Ala Gly Ser 245 250 255 Gly Lys Thr Met Ile Leu Leu Phe Arg Cys Leu Tyr Leu Ala Glu Thr 260 265 270 Thr Ser Gly Ser Tyr Ala Ala Pro Val Gln Leu Pro Gly Gly Arg Phe 275 280 285 His Thr Gly Tyr Cys Arg Ser Pro Pro Ser His Cys Gly Ser Ile Arg 290 295 300 Ser Glu Arg Pro Ile Ala Ser Ala Asp Arg * 305 310 <210> 1136 <211> 183 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5794..6342) <400> 1136 Met Ile Leu Tyr Val Met Ser Gly Ser Arg Leu Ala Asp Asn His Thr 1 5 10 15 Leu Ser Ala Gly Tyr Ala Gln Ser Lys Val Gln Asp Phe Lys Asn Ile 20 25 30 Lys Gly Val Asn Leu Gln Tyr Arg Tyr Glu Trp Asp Ser Pro Val Ser 35 40 45 Val Val Gly Ser Phe Ser Tyr Met Lys Gly Asp Trp Ala Asp Ser His 50 55 60 Arg Asp Glu Ala Asp Asp Phe Tyr Arg His Gln Ala Asp Ile Lys Tyr 65 70 75 80 Tyr Ser Phe Leu Ala Gly Pro Ala Tyr Arg Leu Asn Asp Tyr Ile Ser 85 90 95 Phe Tyr Gly Leu Val Gly Ile Ser His Thr Lys Ala Lys Gly Asp Tyr 100 105 110 Glu Trp Arg Asn Ser Val Gly Ala Asp Glu Ser Asp Gly Tyr Leu Ser 115 120 125 Glu Ser Val Ser Lys Lys Ser Thr Asp Phe Ala Tyr Ala Ala Gly Val 130 135 140 Ile Ile Asn Pro Trp Gly Asn Met Ser Val Asn Val Gly Tyr Glu Gly 145 150 155 160 Thr Lys Ala Asp Ile Tyr Gly Lys His Ser Val Asn Gly Phe Thr Val 165 170 175 Gly Val Gly Tyr Arg Phe * 180 <210> 1137 <211> 54 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6469..6630) <400> 1137 Met Pro Leu Met Gln Ser Leu Lys Glu Gln Gly Trp Phe Val Met Glu 1 5 10 15 Gln His Leu Cys Leu Arg Lys Gly Gly Gly Val Ser Glu Ala Thr Glu 20 25 30 Val Cys Gly Glu Phe Gly Leu Leu Pro Cys Leu Val Phe Cys Gln Cys 35 40 45 Val Gln Ile Val Arg * 50 <210> 1138 <211> 67 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6915..7115) <400> 1138 Val Tyr Lys Arg Gln Val Thr Gly Val Val Asn Lys Thr Ala Asn Val 1 5 10 15 Ala Ala His Ala Val Val Asn Ala Ala Leu Ala Val Val Gln Gly Asn 20 25 30 Asn Ala Arg Ala Ser Ala Ala Gly Ala Ala Thr Gly Asp Val Val Gly 35 40 45 Met Ile Ala Thr Glu Met Cys Gly Ile Ser Pro Gly Thr Val Thr Cys 50 55 60 Lys Arg * 65 <210> 1139 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7644..8534) <400> 1139 Met Tyr Ala Pro Asp Ser Ala Leu Pro Val Asp Leu Ile Glu Gln Gln 1 5 10 15 Cys Trp Ser Arg Ala Thr Asp Thr Tyr Gly Val Lys His Gln Arg Lys 20 25 30 Glu Arg Pro Cys Glu Glu Lys Glu Ser Tyr Arg Trp Gln Gln Ala Ser 35 40 45 Glu Arg Met Ala Glu Arg Leu Arg Glu Ile Gln Lys Gln Val Ile Thr 50 55 60 Val Cys Asp Arg Glu Ala Asp Ile Trp His Tyr Leu His Tyr Lys Val 65 70 75 80 Ser Arg Gly Lys Pro His Ala Glu Cys Asp Ala Lys Arg Arg Ala Gly 85 90 95 Ser Pro Pro Gly Pro Asp Ala His Gln Leu Gln Arg Ser Gln His Lys 100 105 110 Lys Ser Arg Gln Gln Arg Pro Gly Ala Leu Ala His Val Cys Leu Leu 115 120 125 Arg Gly Ala Gly Glu Asp Gly Ala Cys Trp Tyr Pro Leu Thr Ser Glu 130 135 140 Lys Val Ala Ser Ala Ala Asp Ala Arg Arg Ile Val Ser His Tyr Glu 145 150 155 160 Gln Arg Trp Leu Ile Glu Glu Tyr His Lys Ala Trp Lys Ser Gly Gly 165 170 175 Thr Cys Val Glu Ser Leu Arg Met Gln Thr Arg Asp Asn Leu Glu Arg 180 185 190 Met Val Val Ile Ala Val Arg Val Leu Gly Leu Arg Gln Gly Gly Ile 195 200 205 Ser Glu Glu Thr Gln Asn Asp Ser Cys Glu Lys Ile Leu Thr Pro Thr 210 215 220 Glu Trp Lys Leu Leu Trp Val Lys Leu Glu Gly Lys Gln Leu Pro Ala 225 230 235 240 Gln Thr Pro Thr Leu Lys Trp Ala Cys Leu Lys Leu Ala Lys Leu Gly 245 250 255 Arg Trp His Asp Ser Lys Arg Thr Ser Ser Pro Gly Trp Val Val Met 260 265 270 Trp Asp Gly Trp Phe Arg His Gln Asp Met Ala Glu Gly Tyr Leu Val 275 280 285 Met Lys Ser Leu Asp Gln Glu Ile * 290 295 <210> 1140 <211> 76 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8887..9114) <400> 1140 Met Leu Asp Glu His Ser Asn Tyr Ser Leu Ala Val Leu Ser Leu Lys 1 5 10 15 Ser Asp Ile Ile Arg His Phe Phe Cys Cys Val Ala Gln Leu Phe Leu 20 25 30 Val Gly Ile Asn Gln Ile Ile Thr Asp Asp Gly Gln Arg Val Leu Gly 35 40 45 Lys Ile Arg Gln Asn Ala Thr Gly Ser His Arg Arg Val Arg Met Asp 50 55 60 Leu Ser Leu Tyr Ala Glu Asn Lys Cys His Lys * 65 70 75 <210> 1141 <211> 550 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9322..10971) <400> 1141 Met Pro Ile Ile Asn Lys Ser Ala Ser Asn Tyr Val Glu Tyr Ile Ser 1 5 10 15 Lys Asn Asn Pro Pro Tyr Leu Ser Lys Lys Arg Asp Ala Ser Ile Asn 20 25 30 Leu Asn Gly Lys Val Ser Asp Cys Asn Gly Glu Ile Ile Trp Cys Arg 35 40 45 His Ile Ala Ser Tyr Trp Ser Glu Phe Phe Cys Ser Asn Ser Gly Lys 50 55 60 Ile Asp Tyr Glu Thr Phe Ser Ser Pro Gln Leu Leu Ser Lys Ala Ile 65 70 75 80 Val Ile Gln Glu Asn Lys Gly Thr Asn Asn Ile Lys Gly Asp Val Tyr 85 90 95 Phe Val Glu Asn Glu Ser Trp Gly Ser Val Ile Tyr Asn Leu Phe Leu 100 105 110 Gln Leu Glu Lys Glu Asn Lys Ser His Thr Ser Leu Glu Val His Ser 115 120 125 Pro Gly His Ala Met Ala Leu Gly Ile Lys Ile Lys Asn Asp Lys Glu 130 135 140 Asn Lys Phe Val Ile Asn Phe Tyr Asp Pro Asn Gln Thr Ala Thr His 145 150 155 160 Lys Arg Val Phe Phe Cys Thr Asn Asn Ile Cys Asp Ile Ile Asn Leu 165 170 175 Thr Ala Tyr Asp Phe Leu Ser Glu Gln Cys Leu Lys Cys Tyr Gly Leu 180 185 190 Lys Glu Asp Thr Leu Ser Leu Phe Val Asp Lys Thr Lys Ser Asn Asp 195 200 205 Asn Asn Asn Val Phe Ile Lys Lys Leu Pro Asp Asn Ile Leu Gln Gly 210 215 220 Val Val Ile Asn Phe Ala Met Gly Ala Gly Leu Arg Glu Ile Ile Lys 225 230 235 240 Lys Val Tyr Asn Asp Thr Arg Phe Thr Asp Leu Thr Lys Ser Gln Met 245 250 255 Lys Ile Leu Cys Glu Ser Lys Asn Val Asn Asn Val Pro Gly Leu Leu 260 265 270 Leu Ala Leu Gln Asn Gly His Asp Asn Val Ile Asp Glu Tyr Gly Thr 275 280 285 Leu Ile Lys Lys Ser Asn Leu Asn Lys Glu Glu Leu Ile His Ile Leu 290 295 300 Ser Ala Arg Thr Leu Asp Gly Thr Ile Pro Gly Leu Tyr Gln Ala Leu 305 310 315 320 Gln Asn Gly His Ala Gln Ala Ile Lys Ser Tyr Gly Asn Leu Val Leu 325 330 335 Asp Thr Ile Asn Lys Asn Ile Asp Leu Glu Tyr Leu Leu Ser Ala Phe 340 345 350 Lys Tyr Glu Ala His Ser Ser Asn Lys Tyr Thr Pro Gly Leu Phe Ser 355 360 365 Ala Phe Gln Asn Gly His Ala Asp Ala Ile Lys Ala Tyr Cys Gly Val 370 375 380 Leu Gly Asn Ser Asn Leu Lys Arg Gly Glu Ile Ile Arg Met Leu Glu 385 390 395 400 Ala Arg Asn Tyr Asp Gly Ala Pro Gly Leu Leu Leu Ala Tyr Gln Asn 405 410 415 Gly Asp Ile Asn Thr Ile Gln Ser Phe Phe Asp Ser Leu Ile Met Leu 420 425 430 Asp Ile Ser Lys Asp Phe Ile Glu Glu Leu Leu Thr Ala Lys His Tyr 435 440 445 Asp Phe Thr Gly Leu Ser Leu Ala Ile Ser His Arg His Asp His Val 450 455 460 Val Lys Leu Tyr Gly Lys Leu Phe Lys Lys Leu Asp Thr Ser Pro Tyr 465 470 475 480 Lys Met Ser Ile Ile Leu Ala Leu Ala Ile Asp Cys Glu Arg Asn Asn 485 490 495 Ala Asn Ile Ile Ile Asp Ser Glu Tyr Lys Ser Asn Lys Ala Val Lys 500 505 510 Glu Tyr Val Glu Ile Leu Lys Glu Phe Asn Ile Cys Pro Glu Lys Val 515 520 525 Ala Glu Tyr Leu Ser Glu Phe Ser Gly Lys His Phe Leu Asp Val Tyr 530 535 540 Asn Tyr Tyr Ser Asn * 545 <210> 1142 <211> 59 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11162..11338) <400> 1142 Leu Leu Ser Leu Arg Ile Arg Ser Leu Ile Phe Leu Gln Lys Leu Ile 1 5 10 15 Gly Arg Asn Asn Leu Thr Gln Arg Thr Arg Ile Lys Arg Leu Ala Arg 20 25 30 Arg Ile Ile Tyr Phe Ser Arg Thr Val Val Arg Asn Lys Lys Val Ile 35 40 45 Gly Thr Phe Ile Lys Lys His Ile Phe Tyr * 50 55 <210> 1143 <211> 330 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11579..12568) <400> 1143 Met Leu Ser Ser Leu Asn Val Leu Gln Ser Ser Phe Arg Gly Lys Thr 1 5 10 15 Ala Leu Ser Asn Ser Thr Leu Leu Gln Lys Val Ser Phe Ala Gly Lys 20 25 30 Glu Tyr Pro Leu Glu Pro Ile Asp Glu Lys Thr Pro Ile Leu Phe Gln 35 40 45 Trp Phe Glu Ala Arg Pro Glu Arg Tyr Glu Lys Gly Glu Val Pro Ile 50 55 60 Leu Asn Thr Lys Glu His Pro Tyr Leu Ser Asn Ile Ile Asn Ala Ala 65 70 75 80 Lys Ile Glu Asn Glu Arg Ile Ile Gly Val Leu Val Asp Gly Asn Phe 85 90 95 Thr Tyr Glu Gln Lys Lys Glu Phe Leu Ser Leu Glu Asn Glu Tyr Gln 100 105 110 Asn Ile Lys Ile Ile Tyr Arg Ala Asp Val Asp Phe Ser Met Tyr Asp 115 120 125 Lys Lys Leu Ser Asp Ile Tyr Leu Glu Asn Ile His Lys Gln Glu Ser 130 135 140 Tyr Pro Ala Ser Glu Arg Asp Asn Tyr Leu Leu Gly Leu Leu Arg Glu 145 150 155 160 Glu Leu Lys Asn Ile Pro Glu Gly Lys Asp Ser Leu Ile Glu Ser Tyr 165 170 175 Ala Glu Lys Arg Glu His Thr Trp Phe Asp Phe Phe Arg Asn Leu Ala 180 185 190 Met Leu Lys Ala Gly Ser Leu Phe Thr Glu Thr Gly Lys Thr Gly Cys 195 200 205 His Asn Ile Ser Pro Cys Ser Gly Cys Ile Tyr Leu Asp Ala Asp Met 210 215 220 Ile Ile Thr Asp Lys Leu Gly Val Leu Tyr Ala Pro Asp Gly Ile Ala 225 230 235 240 Val His Val Asp Cys Asn Asp Glu Ile Lys Ser Leu Glu Asn Gly Ala 245 250 255 Ile Val Val Asn Arg Ser Asn His Pro Ala Leu Leu Ala Gly Leu Asp 260 265 270 Ile Met Lys Ser Lys Val Asp Ala His Pro Tyr Tyr Asp Gly Leu Gly 275 280 285 Lys Gly Ile Lys Arg His Phe Asn Tyr Ser Ser Leu His Asp Tyr Asn 290 295 300 Ala Phe Cys Asp Phe Ile Glu Phe Lys His Glu Asn Ile Ile Pro Asn 305 310 315 320 Thr Ser Met Tyr Thr Cys Ser Ser Trp * 325 <210> 1144 <211> 225 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12617..13291) <400> 1144 Met Ile Asn Pro Val Thr Asn Thr Gln Gly Val Ser Pro Ile Asn Thr 1 5 10 15 Lys Tyr Ala Glu His Val Val Lys Asn Ile Tyr Pro Glu Ile Lys His 20 25 30 Asp Tyr Phe Asn Glu Ser Pro Asn Ile Tyr Asp Lys Lys Tyr Ile Ser 35 40 45 Gly Ile Thr Arg Gly Val Ala Glu Leu Lys Gln Glu Glu Phe Val Asn 50 55 60 Glu Lys Ala Arg Arg Phe Ser Tyr Met Lys Thr Met Tyr Ser Val Cys 65 70 75 80 Pro Glu Ala Phe Glu Pro Ile Ser Arg Asn Glu Ala Ser Thr Pro Glu 85 90 95 Gly Ser Trp Leu Thr Val Ile Ser Gly Lys Arg Pro Met Gly Gln Phe 100 105 110 Ser Val Asp Ser Leu Tyr Asn Pro Asp Leu His Ala Leu Cys Glu Leu 115 120 125 Pro Asp Ile Cys Cys Lys Ile Phe Pro Lys Glu Asn Asn Asp Phe Leu 130 135 140 Tyr Ile Val Val Val Tyr Arg Asn Asp Ser Pro Leu Gly Glu Gln Arg 145 150 155 160 Ala Asn Arg Phe Ile Glu Leu Tyr Asn Ile Lys Arg Asp Ile Met Gln 165 170 175 Glu Leu Asn Tyr Glu Leu Pro Glu Leu Lys Ala Val Lys Ser Glu Met 180 185 190 Ile Ile Ala Arg Glu Met Gly Glu Ile Phe Ser Tyr Met Pro Gly Glu 195 200 205 Ile Asp Ser Tyr Met Lys Tyr Ile Asn Asn Lys Leu Ser Lys Ile Glu 210 215 220 * <210> 1145 <211> 263 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13726..14514) <400> 1145 Met Leu Met Leu His Arg Ser Ala Arg Val Ser Asp Val Ala Arg Thr 1 5 10 15 Leu Cys Cys Ala Arg Ser Ser Val Arg Arg Trp Ile Asn Trp Phe Thr 20 25 30 Leu Ser Ser Val Glu Gly Leu Lys Ser Leu Pro Ala Gly Arg Ser Arg 35 40 45 Arg Trp Pro Phe Glu His Ile Cys Thr Leu Phe Arg Glu Leu Ile Lys 50 55 60 His Ser Pro Gly Tyr Phe Gly Tyr Gln Arg Ser Arg Trp Ser Thr Glu 65 70 75 80 Leu Leu Ala Ile Lys Ile Asn Glu Ile Thr Glu Cys Gln Leu His Ala 85 90 95 Gly Thr Val Arg Arg Trp Leu Pro Leu Val Gly Leu Val Trp Arg Arg 100 105 110 Ala Ala Pro Thr Leu Arg Thr Arg Asn Pro His Lys Ala Ala Ile His 115 120 125 Lys Ala Leu Asp Glu Cys Ser Ala Glu His Pro Val Phe Tyr Glu Asp 130 135 140 Glu Val Tyr Ile Tyr Leu Asn Pro Lys Thr Gly Ala Asp Trp Gln Leu 145 150 155 160 Arg Arg Gln Gln Lys His Val Val Thr Pro Gly Gln Asn Glu Lys Tyr 165 170 175 Tyr Leu Ala Gly Ala Leu His Ser Gly Thr Gly Lys Val Ser Tyr Val 180 185 190 Gly Gly Asn Ser Lys Ser Ser Ala Leu Phe Ile Ser Leu Leu Lys His 195 200 205 Leu Lys Leu Thr Tyr Arg Arg Asp Lys Pro Ile Thr Leu Ile Val Asp 210 215 220 Asn Tyr Ile Ile His Lys Ser Arg Glu Thr Gln Arg Trp Leu Lys Glu 225 230 235 240 Asn Pro Lys Phe Arg Val Ile Tyr Gln Pro Val Tyr Ser Pro Trp Val 245 250 255 Asn His Val Glu Arg Leu * 260 <210> 1146 <211> 434 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15166..16467) <400> 1146 Met Arg Leu Pro Glu Lys Val Leu Phe Pro Pro Val Thr Ser Gly Leu 1 5 10 15 Ser Gly Gln Glu Lys Gln Lys Lys Pro Lys Ser Ile Thr Gly Phe Gln 20 25 30 Glu Asn Tyr Gln Arg Asn Ile Arg Pro Ile Lys Thr Ala Ser Glu Ala 35 40 45 Arg Leu Arg Phe Phe Asp Lys Met Val Ser Lys Glu Asn Ser Leu Glu 50 55 60 Asp Val Val Ser Leu Gly Glu Met Ile Gln Lys Glu Ile Tyr Gly His 65 70 75 80 Glu Gln Arg Thr Phe Ser Pro Val His His Thr Gly Asn Trp Lys Ser 85 90 95 Ser Leu Leu His Asn Ala Leu Leu Gly Leu Ala Asn Val Tyr Asn Gly 100 105 110 Leu Arg Glu Thr Glu Tyr Pro Asn Thr Phe Asn Arg Asp Gly Ile Lys 115 120 125 Ser Thr Asn Ser Phe Arg Asp Asn Leu Leu Thr Lys Thr Arg Thr Pro 130 135 140 Arg Asp Asn Phe Glu Glu Gly Ile Lys His Pro Glu His Ala Thr Ile 145 150 155 160 Pro Tyr Asp Asn Asp Asn Glu Ser Asn Lys Leu Leu Lys Ala Gly Lys 165 170 175 Ile Ala Gly Asn Asn Asn Glu Leu Leu Met Glu Ile Lys Lys Glu Ser 180 185 190 Gln Ser Asp His Gln Ile Pro Leu Ser Asp Lys Phe Leu Lys Arg Lys 195 200 205 Lys Arg Ser Pro Val Ala Glu Asp Lys Val Gln Asn Ser Leu Thr Pro 210 215 220 Glu Asn Phe Val Gln Lys Ile Ser Leu Ser Asp Glu Leu Lys Thr Lys 225 230 235 240 Tyr Ala Asn Glu Ile Leu Glu Ile Lys Arg Ile Met Gly Glu Tyr Asn 245 250 255 Leu Leu Pro Asp Lys Asn Ser Arg Asn Gly Leu Lys Leu Leu Gln Lys 260 265 270 Gln Ala Asp Leu Leu Lys Ile Ile Met Glu Asp Thr Ser Val Thr Glu 275 280 285 Asn Thr Phe Lys Asn Ile Glu Met Ala Ile Ala Asp Ile Lys Arg Glu 290 295 300 Tyr Tyr Ser His Thr Val Asp Ile Glu Lys Asn Ile His Ala Ile Trp 305 310 315 320 Val Ala Gly Ser Pro Pro Glu Ser Ile Ser Asp Tyr Ile Lys Thr Phe 325 330 335 Leu Lys Thr Tyr Lys Glu Phe Thr Tyr Tyr Leu Trp Val Asp Glu Lys 340 345 350 Ala Phe Gly Ala Ala Lys Phe Thr Ser Val Leu Lys Gln Ile Ala Phe 355 360 365 Asp Leu Ala Cys Arg Thr Ile Gln Gln Asn Thr Pro Gln Lys Asn Ile 370 375 380 Asp Phe Ile Asn Leu Tyr Asn Glu Ile Arg Lys Lys Tyr Asn Asn Asn 385 390 395 400 Pro Ser Gly Gln Gln Glu Tyr Leu Asn Lys Leu Arg Glu Leu Tyr Ala 405 410 415 Thr Tyr Gln Lys Ile Ser Thr Pro Leu Lys His Met Phe Asn Ser Phe 420 425 430 Phe * <210> 1147 <211> 276 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16473..17300) <400> 1147 Met Ile Lys Leu Gln Asp Asn Phe Phe Asn Tyr Cys Ile Val Lys Gly 1 5 10 15 Val Thr Glu Ile Asn Asp Glu Leu Arg Ile Asn Tyr Leu Lys Asn Val 20 25 30 Ile Lys Leu Ser Asp Asp Asp Ile Gly Asn Tyr Gln Lys Thr Ile Asn 35 40 45 Asp Asn Lys Asp Arg Val Lys Lys Leu Ile Leu Asp Leu Gln Lys Gln 50 55 60 Phe Gly Glu Asn Arg Ile Ser Ile Lys Asp Val Asn Ser Leu Thr Ser 65 70 75 80 Leu Ser Lys Ser Glu Asn Asn His Asn Tyr Gln Thr Glu Met Leu Leu 85 90 95 Arg Trp Asn Tyr Pro Ala Ala Ser Asp Leu Leu Arg Met Tyr Ile Leu 100 105 110 Lys Glu His Gly Gly Ile Tyr Thr Asp Thr Asp Met Met Pro Ala Tyr 115 120 125 Ser Lys Gln Val Ile Phe Lys Ile Met Met Gln Thr Asn Gly Asp Asn 130 135 140 Arg Phe Leu Glu Asp Leu Lys Leu Arg Arg Ala Ile Ser Asp Gly Val 145 150 155 160 Leu Arg Tyr Val Asn Asn Gln Asn Ile Asp Glu Val Asn Tyr Asn Glu 165 170 175 Ile Ser Asp Ala Asp Lys Asn Ile Ile Lys Lys Ile Leu Thr Glu Ile 180 185 190 Ser Lys Met Pro Glu Asp Ser Ile Phe Thr Lys Ile Asn Thr Arg Ile 195 200 205 Pro Arg Asp Thr Met Pro Ile Leu Arg Arg Tyr His Leu Trp Pro Asp 210 215 220 Gly Trp Asn Ile Arg Gly Leu Asn Gly Phe Met Leu Ser His Lys Gly 225 230 235 240 Ser Glu Val Ile Asp Ala Val Ile Ala Gly Gln Asn Gln Ala Tyr Arg 245 250 255 Glu Leu Arg Arg Ile Arg Asp Asn Ile His Ser Glu Ile Tyr Phe Lys 260 265 270 Gln Thr Asp * 275 <210> 1148 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17340..18230) <400> 1148 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 1149 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18227..18553) <400> 1149 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1150 <211> 39 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18559..18675) <400> 1150 Val Pro Glu Arg Tyr Leu Thr Ala Asp Thr Glu Gly Phe Arg Val Leu 1 5 10 15 Cys Glu Arg Phe Trp Leu Cys Glu Pro Pro Arg Lys Ser Trp Arg Leu 20 25 30 Asn Ser Leu Arg Lys Arg * 35 <210> 1151 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18744..19091) <400> 1151 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Tyr Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 1152 <211> 464 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19288..20679) <400> 1152 Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala Gln 1 5 10 15 Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu Thr 20 25 30 Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr Arg 35 40 45 Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg Leu 50 55 60 Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser Tyr 65 70 75 80 Leu Gly Glu Asp Thr Ala Glu Gln Leu Glu Leu Met Arg Ser Ala Phe 85 90 95 Arg Val Ile Arg Thr Val Arg Glu Lys His Ala Cys Thr Gln Cys Asp 100 105 110 Ala Ile Val Gln Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly Ile 115 120 125 Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Ser Lys Tyr Ala Glu 130 135 140 His Thr Pro Leu Tyr Arg Gln Ser Glu Ile Tyr Gly Arg Gln Gly Val 145 150 155 160 Glu Leu Arg Arg Ser Leu Leu Ser Gly Trp Val Asp Ala Cys Cys Arg 165 170 175 Leu Leu Ser Pro Leu Glu Glu Ala Leu His Gly Tyr Val Met Thr Asp 180 185 190 Gly Lys Leu His Ala Asp Asp Thr Pro Val Gln Val Leu Leu Pro Gly 195 200 205 Asn Lys Lys Thr Lys Thr Gly Arg Leu Trp Ala Tyr Val Arg Asp Asp 210 215 220 Arg Asn Ala Gly Ser Ala Leu Ala Pro Ala Val Trp Phe Ala Tyr Ser 225 230 235 240 Pro Asp Arg Lys Gly Ile His Pro Gln Thr His Leu Ala Cys Phe Ser 245 250 255 Gly Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr Arg 260 265 270 Asn Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg Lys 275 280 285 Ile His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu Ala 290 295 300 Leu Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg Gly 305 310 315 320 Met Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys Pro 325 330 335 Leu Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr Leu 340 345 350 Ser Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn Gln 355 360 365 Trp Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile Asp 370 375 380 Asn Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg Lys 385 390 395 400 Asn Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala Leu 405 410 415 Leu Tyr Ser Leu Ile Gly Thr Cys Lys Leu Asn Asp Val Asp Pro Glu 420 425 430 Ser Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val Asn 435 440 445 Arg Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu * 450 455 460 <210> 1153 <211> 53 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20747..20905) <400> 1153 Val Ala Ala Ile Ala Pro Ser Leu Ser Thr Ser Thr Gln Thr Arg Val 1 5 10 15 Ser Ala Ser Ser Cys Lys Val Glu Phe Arg His Gly Asn Met Thr Leu 20 25 30 Glu Asn Pro Ser Pro Glu Leu Leu Thr Met Leu Ile Arg Glu Leu Ser 35 40 45 Gly Arg Gly Arg * 50 <210> 1154 <211> 117 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20902..21252) <400> 1154 Met Ile Ser Leu Pro Ser Gly Thr Arg Ile Trp Leu Val Ala Gly Val 1 5 10 15 Thr Asp Met Cys Lys Ser Phe Asn Gly Leu Gly Glu Gln Val Gln His 20 25 30 Val Leu Asn Asp Asn Pro Phe Ser Gly His Leu Phe Ile Phe Arg Gly 35 40 45 Arg Arg Gly Asp Thr Val Lys Ile Leu Trp Ala Asp Ala Asp Gly Leu 50 55 60 Cys Leu Phe Thr Lys Arg Leu Glu Glu Gly Gln Phe Ile Trp Pro Ala 65 70 75 80 Val Arg Asp Gly Lys Val Ser Ile Thr Arg Ser Gln Leu Ala Met Leu 85 90 95 Leu Asp Lys Leu Asp Trp Arg Gln Pro Lys Thr Ser Arg Leu Asn Ala 100 105 110 Leu Thr Met Leu * 115 <210> 1155 <211> 468 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21465..22868) <400> 1155 Met Leu Phe Gly Thr Arg Ser Glu Lys Leu Arg Arg Glu Val Glu Gln 1 5 10 15 Ala Glu Ala Leu Leu Lys Gln Arg Glu Gln Asp Ser Asp Arg Tyr Ser 20 25 30 Gly Arg Glu Asp Asp Pro Gln Val Pro Arg Gln Leu Arg Gln Ser Arg 35 40 45 His Arg Arg Pro Leu Pro Ala His Leu Pro Arg Glu Ile Gln Arg Leu 50 55 60 Glu Ser Glu Glu Ser Cys Cys Pro Glu Cys Gly Gly Glu Leu Asp Tyr 65 70 75 80 Leu Gly Glu Val Ser Ala Glu Gln Leu Glu Leu Val Ser Ser Ala Leu 85 90 95 Lys Val Ile Arg Thr Glu Arg Val Lys Lys Ala Cys Thr Lys Cys Asp 100 105 110 Cys Ile Val Glu Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly Ile 115 120 125 Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Gly Lys Tyr Cys Glu 130 135 140 His Leu Pro Leu Tyr Arg Gln Ser Glu Ile Phe Ala Arg Gln Gly Val 145 150 155 160 Glu Leu Ser Arg Ala Leu Leu Ser Asn Trp Val Asp Ala Cys Cys Gln 165 170 175 Leu Met Thr Pro Leu Asn Asp Ala Leu Tyr Arg Tyr Val Met Asn Thr 180 185 190 Arg Lys Leu His Thr Asp Asp Thr Pro Val Lys Val Leu Ala Pro Gly 195 200 205 Leu Lys Lys Thr Lys Thr Gly Arg Ile Trp Thr Tyr Val Arg Asp Asp 210 215 220 Arg Asn Ala Gly Ser Ser Ser Pro Pro Ala Val Trp Phe Ala Tyr Ser 225 230 235 240 Pro Asn Arg Gln Gly Lys His Pro Glu Gln His Leu Arg Pro Phe Arg 245 250 255 Gly Ile Leu Gln Ala Asp Ala Phe Thr Gly Tyr Asp Arg Leu Phe Ser 260 265 270 Ala Glu Arg Glu Gly Gly Ala Leu Thr Glu Val Ala Cys Arg Ala His 275 280 285 Ala Arg Arg Lys Ile His Asp Val Tyr Ile Ser Ser Lys Ser Ala Thr 290 295 300 Ala Glu Glu Ala Leu Lys Arg Ile Ser Glu Leu Tyr Ala Ile Glu Asp 305 310 315 320 Glu Ile Arg Gly Leu Pro Glu Ser Glu Arg Leu Ala Val Arg Gln Gln 325 330 335 Arg Ser Lys Ala Leu Leu Thr Ser Leu His Glu Trp Met Met Glu Lys 340 345 350 Asn Gly Thr Leu Ser Lys Lys Ser Arg Leu Gly Glu Ala Phe Ser Tyr 355 360 365 Val Leu Asn Gln Trp Asp Ala Leu Cys Tyr Tyr Ser Asp Asp Gly Leu 370 375 380 Ala Glu Thr Asp Asn Asn Thr Ala Glu Arg Ala Leu Arg Ala Val Cys 385 390 395 400 Leu Gly Lys Lys Asn Tyr Val Phe Phe Gly Ser Asp His Gly Gly Glu 405 410 415 Arg Gly Ala Leu Leu Tyr Gly Leu Ile Gly Thr Cys Arg Leu Asn Gly 420 425 430 Ile Asp Pro Glu Ala Tyr Leu Arg His Ile Leu Ser Val Leu Pro Glu 435 440 445 Trp Pro Ser Asn Arg Val Asp Glu Leu Leu Pro Trp Asn Val Val Leu 450 455 460 Thr Asn Lys * 465 <210> 1156 <211> 57 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(22960..23130) <400> 1156 Met Arg Glu Thr Val Phe Asn Tyr Ile Glu Cys Asp Tyr Asn Arg Trp 1 5 10 15 Arg Arg His Ser Ala Cys Gly Gly Leu Ser Pro Asp Cys Leu Ala Leu 20 25 30 Gln Ile Phe Arg Asn Glu Ser Met Gln Phe Thr Ser Lys Ile Ser His 35 40 45 Gln Arg Gly Asn Val Val Ala Gln * 50 55 <210> 1157 <211> 21120 <212> DNA <213> Escherichia coli O157:H7 <400> 1157 aaaaaaccac ccgaaggtgg tttcacgaca ctgcttattg ctttgatttt attcttatct 60 ttcccatggt acccggagcg ggacttgaac ccgcacagcg cgaacgccga gggattttaa 120 aaactatcaa ccaccattta taaatcataa ccttatgatt ttattaactt tgaaaatggc 180 tctatacaac gccatttgaa tctattgtca ctttttatcg ccacttttta ccctctattg 240 tcaaaagggt tcaattcaac agcagcctct aaatgacctg gagcaaaatg cgcataacgc 300 atagtcattt ttatatcgct atgccccagt attttttgca acacaagaat atttccaccc 360 cgcatcataa aatgactggc aaacgtgtga cgtagcacat gagttaattg cccatcagga 420 agctcgatct tcgctctctt aattgcagcg tcaaaagcct cataacatgg tgaaaatagc 480 gctcctcgtt ttttaggaag catagcttgc aattgaggtg aaatcggtac agtgcggttc 540 ttctttcctt tagttttaac aaatgtgatt cgaccgggca gtacttgaga ttgctttaat 600 ccttctgctt cactccaccg agcaccagtc gcaagcccaa tacggacaac aacccccaaa 660 tctttattcc gtgactcatc acacgcaatc agaaggcgtt caatctcatc tacatacaga 720 aacgccagtt ccttttcttc ctcacgaaac ttgcgaatac cagtcagggg gttttcacca 780 gaccactccc caaggcgctt cagttcggca aaaacagcat gtagatatga ctgctcgcga 840 ttaacggttg cttcactaag ttttttcttc cccttgggat tccattctcc tgatagcctt 900 ctttcccgat aagtagcaaa catatttttg tcaaactgag aagcaaatgg atctcccagc 960 ctggaacaaa tcgcctcaag tttgactttg cgctctgcac cagaggacaa ggttttaccg 1020 tacatctcaa accaacgagc aatcaactca gaaagacgag gaccagaacc atcttgaaac 1080 tcgtctccaa ctctactatt cattaaacgg cgctcataag agagcgcctc actttttgtc 1140 gcaaactgtt tacgaatgcg ttttcccgat gccccgtagg gataacattc acaaagccat 1200 ttacctgatg gaatcttacg aaccgacatt ttagttactt atcacataaa tcaaatgcag 1260 ccttagtgac atcccccaga ctctttttta accctggggc ggcatcatta tctagccaaa 1320 atggattatt gttatctaac ggtaacgcac caaatgtttt accttttatt cgagccaaac 1380 ctgtaagtgc atataactta ttatcgtcaa aattcatcac ataaggatta ccatcaagac 1440 actgtaattg aacctcatca gtattaaatg gccatacccc attgaaactc tcacgttcaa 1500 tagttttaaa aggcattgcg acggcggaaa aagaaaacat agataaaaaa gtaactaata 1560 gttgaacctt ttttactttc atatcattac ctcaatttag ctcaagtaag attacaaatt 1620 aaaaaacgcc ctagaaatga caccgcctac caaaacccct acgcagataa agaatattat 1680 ttcttttgga taaagtcgga ttaattctga agcacgaagt cggacttctg gtaaggtcga 1740 actctctatg tggcttgatg ccgattgttg ctctaaccac gacaatgcag actgtaactg 1800 agaacgagta agatcgttta aacgtcctgt accgaaattg atatggcaat accgcagaag 1860 tttttgtcga agtccacagt cttcactgtt acgtagtaat aaacttacaa gagccttaca 1920 ggcatcatga tctttacatc gctcaagcat tgcatgcaga aaactctccg ctgttttata 1980 ttgatttact gtcatatcat caataccagc tacaccaatc tccgcatgta ctttttgcca 2040 aataataaac gcttcagtat tgctagcttc tgcaatagca gcaaccaagc tatttagctc 2100 cttacgctga gccttaagca aagggcgatc gtcatcatca ttattcgaag ggattgcgat 2160 attgacggta tgagaaccat catatcgctc tatctgaata ttcttttcgt gaaaatcacg 2220 cccagcaacg cgattgtttg aaccgtttga gttgacggcc atgtcacctc cctactatca 2280 cctaccctta gtttcgttat agtcacgacc agcgatacgg ttattaccac cagaaatatt 2340 taactcacgt cctgatggct gagtttcctt ttcactgatc gcacctttta aagccccaat 2400 caccgcgttt ttcacatcta acgaagctgc tcgaaagcga gtaatcaatt cctgctcatc 2460 atcgttataa gtttcaggtg agtgaattcc caacacaaca tactgaacat caaggccaaa 2520 acgagacagc gctgccaaat acgcagcatc aggaaagcta tctcctttct catatctaag 2580 ctgagttagc tttttgactc caccaatgtc gctcatggca acttgactaa gtcccaatct 2640 ttccctttcc tcacgcaacc gccgaccaat atcatttttc atacaaaaac cttgacaggt 2700 atcttttttg ataccaaaat gatttcacga gctattagat gatcacaata taccactatg 2760 aaacaagttc ttcacgatac cagatcacgc attccgcgta acaccgccac aggtccaaga 2820 ctggcacttc ggctgtccct cgaggagcga gccgtcattg atgaaatggc agctaaagaa 2880 caacgctcat cctctaacat ggcgcgcatg atctcccttc gcggcctaga gctaacccag 2940 aaagaacaaa acaaatcttc ctgatcagga ggctagtggg atgtcaggta taaccatcaa 3000 tatcaatgtg aatgccccct atgtatccct gcagaaatat gcagagataa caggtatccc 3060 tcttaataca tgcaaaaaga tgttggctga cggtcgaatt attatccgcc ccaaacgcgc 3120 caaaatggaa aagcctgaag taaaccttgt ggcgatgtta aaagacgctt tggctaacag 3180 ctaaaacaat gaacagagca ccatcatgaa aaaaaacgct aataatccat actccaaatt 3240 tcgtaatggc gtagaacgcc atgtacacca cgtcgctacc agtgcatcac gtagtaacag 3300 tcgctataac ctgaacgaga cgcatgcaac accggatggc cacgctgtaa aacaaatcgg 3360 cgaacatgcc tggctgattg agaaagctgg aatcgtggtc cacaaatgcc cacgcaatcc 3420 gtttaccggg aaccgcattt ttgcattgaa ctgcggcgac aatcacttcg ggcaggattt 3480 cacattatac gaagcacttc gcacggttga tcgtctgctt cgcgggcaaa gttttattaa 3540 acaggctgat ttataacagg tgctttatga ccaaagagca tgcacaaggt gtatttatcc 3600 gttttattga ttttcgcggt gaactgttat tacgcgcatc agccattgac ggaattgttc 3660 catccgaaaa aaacgcagct acttacgttt atctgaacgg tacgcgcctg actgtggagc 3720 ttccgtacca gaccgtacga gaaatcatta gcgaagctga aaaggctcgt caggttaatg 3780 gcgatgaacc ctatatcgaa attatttgta tggattcaga agctgaaatt cagaaagcag 3840 attaaagggc gttgcgatgg gcaaagaata taaaactctc attaacaaag cacctgaacg 3900 attttatttt cgcttaagtg catcaggcgc tcatgctgaa cgtgcagccc gtgactcatt 3960 gaccagggca atccggagtt tgtatgacgt tgctttttac gctgatgatc tggatgcact 4020 taacgaactt tccgagctga tctgtgccgc agaatgcggg gaacacattg aaccatataa 4080 gctggggaat atcgcatgag tatatttatc tcatggcttg ttctgattat ttcggtggcc 4140 tgcgccattg ggattatgcg aattattcat tcagtaaaaa agattgaacg ctttttcact 4200 gacaaataac agcttaaaca gaacaccaga ttaaacccga aaacctgaaa actatccgca 4260 ttcgcggagg tattcgcaca cgtaaataac ggagatataa aatgaacgca aaagaaaaaa 4320 atattatcaa tacattaaaa atagtgtcag cagagcaaga caagctgtcc agggcagccc 4380 agaaagataa tcaacatatg gcagcgcttt acgcactgac catcgcaata gccacccctg 4440 aagcagccaa agttattgag gaacagagca aagaaatcga cactcttaaa acacagtcaa 4500 cagttgcagc catgaatccg tccagcattg gacgctgcat ttatattctt ggttcagcaa 4560 tgatgctgca atacaccatt attgccgaac tgcacggcaa atacctgata acgccttacc 4620 acacaaaaga gtcagagctt ctgacaaatc tccgcctgat agaacgctct caagctgtat 4680 tcattgatga cgcgcaacgt gccgtattta acgcataggg ttactggaca aagggggcgc 4740 aatggcaatt aagcattttc ccgtcgttcg ctttacctcc agagggcgcg aatacgaggt 4800 cgacgaacgc ctgattacca ctatcgacaa acatcgttcg gaaaaggatg cacaccacat 4860 ctacctcact gacggcactt acttctgcgc caccaacgtg gcgcgagtaa atcttatccg 4920 acaggtacag gagccacgca gatgaccatt ctggactaca tcgctactca tccggggtgt 4980 agcggcggag agatcgccgc agcactgaat accccaacca cagccattaa tgctgagtta 5040 cgccgacttt ggcgcggcgg cttagtcatc agaacaaacc gcagcacagg tggtcgcgct 5100 cgcaaaacag gaggccaggc ttcttaccac gtaaacccga tgccgttcgg gtgtagcaat 5160 ccacttactc acatgtttaa ccagctactg aaggaagcca gagcatgagc accatcaacc 5220 accagaagct acgcgaactg gcatttgccc tgcaacgaat ggcaacgcct caaaaattac 5280 tggcatttcg cgcaatgctc tcgccgtctg ctgtgctggc actgctggat cagctggagc 5340 acgccagaac cacggctcct gccattcgcc tcacgctcca tcatgaaatc gctgatttct 5400 gcgcaacgct gggggcacct ggcgaaccgg aaacgccgga agcaatgcag caagagctgc 5460 tgcaacgcat cgataacgtt tttgattttt ttctgaacca gtaagaaacc agaacatgca 5520 cacacaaaaa aaccgcttgc catgccgcaa tcggtcaggt tacatttccg ctgcacctca 5580 taaaacgggt gccgggattc tcaacccgat acagagcaaa gcgcataacc gcgctagcgg 5640 tttttttgtg cgtactgtat tgccacgtct ttttcgcgtc agaattatgg cggggcgtac 5700 ggggccgact tcggtcgggc cggattcttt gctctccggt gttgagaacc ctgtacgtct 5760 cgccagcccg agattctcaa ctctggatgg tgagttattt ctatcaccga gcaaagaggc 5820 cacaccatgg cagaccgcaa acagcaccgc gctatcgcgg agcgtcgtca catccagact 5880 gaaatcaacc gcagactttc ccgcgcatca cgcgtcgcgc aaatcatgca catcaatatg 5940 ctgcatgagc gcagccacgc actatcaaac atttattccg cctctgtttt cagctatctg 6000 gcggatgatc tgcacgagtt tcaacagctc atccagcagc aaaacaaact ccattaattc 6060 ctgttccggg cctttcctgc accttgcggc gggaggcctt cgcacatctg taacaagagg 6120 attgccgcaa tgattctcgc caacgacttt cttgaatacc tgctcaacac agaacgtgat 6180 cttgccgctc gcgtgcgtga tcgttatgac atgtacctga aatccctgcc tgtaccgcag 6240 ctcgctgacg gaaagattgt tattgatggt cgctacatga ttgacagcca cgagggaaat 6300 tacaggcttt accgcattga aggtggcacc ccgtccgtta ttggcattta ccagcgccca 6360 tcctctgcaa tcgtcgatgt gattgccgac agcatccgca tcacacatcg ccatgccgac 6420 acagaagaca ccgtgctgga aattcagcgg ctggctacag cctgccgcga caccctgaat 6480 ggcatgacga agtaaatcac tatgacggca gagtacatca gggactggca acaaccgcgc 6540 cacgcagtgg ggcgtgaagg aacggggatc cccgctcctg aatccgcgct ttcctcctgg 6600 ctggatgcct accgggtaga gaacgagcgc cgccaggaaa tggctgatgc ggcgttctcc 6660 gcaacgccgc tgggcaacct gattaataaa agcctggacg cacaggaaaa acaggacaaa 6720 accatcacac tggcaggaga cgccagaaaa caggcacgcg gtgcggtgga tgaagccatg 6780 gcctcgctgc gcctgctgcc gtcctatctg cgcgatccgc ttattcgcca cctctccttc 6840 ctgcgcaaaa aacaggaagc cgatcgtcag aaaggcaaaa agagctggca ggctgaacgc 6900 tacgcgcgcg gaaacctgcg caaaatattc gaacgtctgg agcgcaccga tcaccgctgg 6960 ctgacacagg gttatcgctc ccttgccgga cgcgaacgcc tggacgattt gctttacctg 7020 ccgcagctca acaaacacca gatacagacg ctggccacca tgacggcggc gatgttcagc 7080 agcaccttcg aaaaactctg cgatggcttt ggcgcgaccg atggcgaact gaccatggat 7140 gtaacgctga aggcgtatca gatgctggcc cgcatggcgt tacacctgca cgccatgcct 7200 ccacattatg acgcactgac aacagacaaa gaccggagga acgaaccgga cacggagctg 7260 ctgccgggcg caatccttcg cctgacctgt gcggaatggt ggaaacgcaa actgtggctg 7320 ttacgttgcg agtggagaga agaacaactc cgcgccgcct gtctggtttc cagaaaaaca 7380 tcgccctatc tgagccagga cgcgttaagc gagtttcgcg cacagcgcga gaaaacacgc 7440 gatttcctga aaagtttcat gctggaaaac gaagacgggt tcacgattga tctcgagaca 7500 gtgtattacg cgggagtaag taacccggtt caccgtaagg cagaaatgat ggccaccatg 7560 aaggggctgg aacttctggc cgaagcccgt ggcgacaaag cggtgtttct gactgtcacc 7620 tgcccgtcaa aataccacgc tacaacagag aacggtcatc cgaatcccaa atggaacggg 7680 gccaccatgc gcgactccag cgattacctg gttaacacgt tttttgcggc ggtccgcaag 7740 aaactgaacc gcgacggcct gcgctggtat ggcatccgca cggtggagcc tcaccatgac 7800 ggcaccgtgc actggcatat gatggtcttt gctcatccgg aagaaatcga caccattgtg 7860 tcccacaccc gcgatattgc cattcaggaa gatcgtcacg agctgggcga tgatattact 7920 ccgcgcttta aggcggagta tgtcgacggc tcaaaaggca cgccaaccag ctacatcgcc 7980 acctacatcg gaaaaaacct ggacagccgc gccgtggatg gcatcgaccc gaaaacaggc 8040 aaaccacgcg ttgaccacga aaccggaaaa tcaatgaccg agagcgtgga acgcgccatt 8100 ggctgggcgc gccttcaccg ggtccgccag ttccagttct ttggcatccc ctcccgtcag 8160 gtgtggcgtg aactgcgtcg ccttgccagc cagatggcac gcaacccgga aggcccgcaa 8220 cggctgaagg atgacgcaat ggatgcggtt cttgctgccg ctgatgccgg atgttttacc 8280 acctacattg agaaacaggg aggcgtactt gttccacgca aggactacct gattcgcacc 8340 gcctacgacc tcgcagatga gctgaacgat tacggcgaac agagcgtaca gatttacggg 8400 atctggtcac cactcatcgg ggaatcctcc cgtgtgtgca cgcacccgga taactggaag 8460 ctggtaagac gtaaaccggg agtagaagac agcgcccgcg aaaatggttt tgaccttcag 8520 ggcggccctg ccgccccttg gactcgtggc aataactgtc cccgtgtaca ggaaacggac 8580 aacaacggga cagaacagcc ggaagaacgg ccagcaccgt ggccgcagct tcctgacggc 8640 gttgacgtga acgaatggat gcgctcactg aaacggcacg aacgccgggc gctgatgcgt 8700 tcgcttcgtg acaaacaggc aaaaaacagc agtgatgaaa tgcagagctg gacacagagc 8760 cgcaaacagc agcggccttt gcctgataac cacgaattac tcgctaaaga atggcgggag 8820 tctgctgaat ctctcggcct gcatatcggt gaacaacaga tgcagcacct gttacggggc 8880 ggcagtctgt acgttgacgg cagcatcatt gcaccgcagg gatttgaaat tgtacgcaaa 8940 ccggataccc gcccggacag ccgaatcacg cagctctggc agcgcctgag ccgtaatcat 9000 ggcgtaagca gcacggagat ccgccataac ccggtcgcca gctatctggc acagctgggg 9060 gcatcagacc ctgaagccgc cgcacgcctg gcatccacac ttcagcagga ccagaacacc 9120 atgaaaacac ccgttaccgt gctttctgac atgctgcgcg ccatccgcga cgcagagcac 9180 gcacagagaa tcagtgaaac cactgaacgc gccagccgca aagcagacct gctgcggggt 9240 ggcctgacca gtggaaacaa aaaacagaca gaaacgggac tcacaaatcc cgtaaatgag 9300 caaaaaacgc gccgcgatat atgaagcgcg cacaaaacag gcaaaagcgg gatttaaaaa 9360 tcctgtaacc gattaattaa tcaacataag gaaaagcgac atgaaaattt gtatcgacga 9420 cggctccacc aacatcaagc tggcatggac tgagaacggc gaacgccgca acgccatcag 9480 cccgaacagc ttcaagtcgg aatggtctgc gccattcggt ggcacgcagc ccgcgaacta 9540 catgcttgat ggcgtgcgct atggttttga tccggtcagc gatcgctttg tccagacgac 9600 cgacacgcaa taccagtaca gcgatgtgaa tgtaattgcc attcatcacg cgctggtcaa 9660 atcaggcatc acaccacagg aagtggatgt ggttgtcacc ctgccactga gcgagtattt 9720 cgatacaaac gcacagccgg acatggccaa catcaaccgc aaaaaagcga acgtcatgcg 9780 cccggtggag taccagaacg gcgaagcatt cactatccgt aacgtacggg ttatgcctga 9840 atccattcct gctggcttta aggcaccggc tgacatgagt ccgtttgaat ccctgctgat 9900 tgtggatttg ggcggaacca cgctggatgt ggcaaaggtt caggggcaac tggcaggtat 9960 cagccaggtg ttttgcgatc cacacgtagg cgtttctctg atggccgatg ccgtactgtc 1002 0 ggtgatggcc actaacggta tgcgcaccag tcaccacatc gccaatacca ttatcgaaca 1008 0 tcgccatgat gaagcctggc tgcgccagca catccacaat gacgcgcatt acgccagcct 1014 0 gatggcggtt attcgtgaaa aggaagaaac actgaaacaa cgcgtgatcc gcgcgctggc 1020 0 ggttttttcg ggttacgggc gggtgatggt tgtcggtggc ggggcggaga ttgtggcaac 1026 0 cgctatccgc gaagcctgcg gagttaatgc gactttcatc gcggacgggg tgccacagtt 1032 0 tgctctggtt aatgggttgt acgcaatgaa caaggagtaa accaatgacg acaccaacca 1038 0 gacggataag tttctatctg aagcccgccg ccgtcaagag tgaacaggag gcgtgcaatt 1044 0 acctcgatag cctgccagcc tccgaacgca gccgcgcgca acgcgcggcc tttctggctg 1050 0 ggctagcact cataaagcgc aacccagcat ttgcctactg gatggccgaa tggccagagg 1056 0 acaacctccc cttcaatacc gttagcatca aggaaacata ccaggctaat cagcctagcg 1062 0 gagttgaatg caatttttat aaaataaaaa agaatattca gaccttattc ccagaataat 1068 0 ctgataattg tatgtgaact aataaaatac attgtcatac gagtcacctg tactccctgt 1074 0 tgatgccagc agttttgctt cttttagtcg ctccgtatag gccagtgata catactgaga 1080 0 acctttatca ctgtgatgga ctgtgccgga cggccgacgg gcccacaacg cctgctccag 1086 0 tgcatccagc acgaatgtcg tttccataga cgatgagact cgccacccca cgatacatcc 1092 0 ggaaaacaca tcaatgatga acgccacata gacgaagccc tgccatgtgc tgacgtaagt 1098 0 aaaatcagcc acccacagct ggtcaggacg ttctgccacg aactgacggt ttacgcggtc 1104 0 gcctgcggaa acggctttcc ggctgacggt agtacggacc tttttacccc ggagaacacc 1110 0 ggcaagtccc ataaccgcca tgaggcgcgc cactgtacat ctggccaccc tgataccttc 1116 0 gcgtaacaac tggcgccaga ctttacgcac accgtacacc tgatgatttt catcgtatac 1122 0 gcgctgtatc tctctcttca gccagtcatc gcgctgcgca cgggcactgc gtttatccgg 1128 0 atgatgtcgc tgttgctgac agtggtaata cgttgacggg gcaatatgca gttcactgca 1134 0 taccggtccg accccgtact gctcacgcag cttatccagc agcggcatta ttttttccag 1140 0 aggcggtcga actccgcctt cgcaaaataa gcggaagcct ggcgaaggat atcgttactg 1146 0 cggggcagtt cacgattttc acgttccagc tctttcagac gctgacgttc agcggtggtg 1152 0 agtccaccat caccgccccc ggtatcccgc tcatgctgac gaacccacac acgcagagtc 1158 0 tctggtgtac agccaatctt tggggcaatg gaacaaattg ccgcccattg tgagtcatat 1164 0 tcgccctgac tttccagaac catacggact gcccgttgac ggacctcggg ggaaaaacgt 1170 0 gtatttttag tcatcctgtt tacctctttc tcagggagtt tagtctccag gattcccggg 1176 0 gcggttcaat ctgctggccg gaactaatga atttattggt gaaggtgacg catacattcc 1182 0 gcctcataca ggtctgccag caaacagtac cgatattgca ccgccagata ttccggctgg 1188 0 cttcgtggct gttttcaaca gtaatgaggc atcgtggcat ctcgttgaag atcatcgggg 1194 0 taaaacggtt tatgacgtgg cttccggcga cgcgttattt atttctgaac tcggtccgtt 1200 0 accggaaaat gttacctggt tgtcgccgga tggagagtgt cagaagtgga acggcacatc 1206 0 ctgggcgaaa gatgcagaag cagaaaaact gtttcgggta cgggaggcag aagaaacaaa 1212 0 aaacagcctg atgcaggtag ccagtgagca tattgcgcca cttcaggatg ccgtagattt 1218 0 ggatattgcg acggaggaag aggcatcgtt actggctgca tggaagacat atcgggtatt 1224 0 gttgaatcgt gttgatacaa cagtagcagc ggatgttgag tggccagtcg ccccacaata 1230 0 aaaagaaaaa gccatcgaca gaaatatcga tggctttatg tactctattt atacaataca 1236 0 acaccactct ttttagttat atatgtgcag tttgatggta tatctttatt tataaaagac 1242 0 attgcaccta tttttacatt atccccaatt ttacgtgata atccaatgat gcaacaatta 1248 0 gctccgatat caacgttact accaattttt actcttgaac taggcatatc accatctatc 1254 0 tgtccaatgg tagtattctg tcgtaatacc agattttcac ccgcatcaac agcaaaatga 1260 0 acaacaattc cagcatgatg gggaattgtc aacccttttc caatatttgc gcccaatcct 1266 0 atttcacaac caaacttgtt aattatttta ctgtttaact ttttggctgc tttcttatgt 1272 0 aatttattac cattaatata catttcgtta gccaaccgcc accagaaaag gaaattccgg 1278 0 ttacgctgct ttttctctct taaaagcctc cagatatcca tacgtttccg ccgaattact 1284 0 tcatgtttcc agaagttttt taaattagta gagtttccaa ataaaacaaa gtgaattgcc 1290 0 attaagtaag atagcacgat aatctcctta attattattt cagaccacac atgttataag 1296 0 gttaagagat tataaaatcc tgttatttgt tattcaaaaa caattttctg agaaggacat 1302 0 acaacagcaa gtcgccagtc accttcatca ggaaattggc gacatacgtt aaatcagagc 1308 0 agccccttaa ctgagctggc cgcgctatta agggatgatg tcaccttatc tttgaagccg 1314 0 gacagcatat cgctgaacga tgaggattgc aggcgctccc gcaaatcctc atcacagcgt 1320 0 tcaagagtca gtgaaaattc tatctttttc gccttaccgt agcgatcaaa ctcggagcgg 1326 0 gtcgtattcg ttccggtcag gacatacatg ccgtaaatct gcccgacgcc atcaatcaaa 1332 0 ggccaaggac gtcctgtata tgcctgcgtg gtcaacaacg acagcgacac ttcgccacca 1338 0 gtaatctcag gataaagaac accagaaaga acgatgcgat catcacctgc accgatatac 1344 0 tgccagcttg ctgaacggtt aacgcgttca tttttcacat gtcgccagct tttgttttgc 1350 0 tgtaactgct gatgcggcaa cgtgcgcagc tcaaaaacaa acatgccgta gatcatcatc 1356 0 atggccatga ctcctcaatc tttatcgtaa aaactgccac gcctggcacg ggcgcgccgt 1362 0 tccatttctg ccctgaccat ttcgccgacc agtttcgcca gttcgcgggg attctgcgta 1368 0 acaacgttat gcagatgaac atgaatttca ccgccaaatc cggaggcaac aggctcccgg 1374 0 ttacgggaag ttgcaggaac tgatgccact ggcgatcgta tggcctccac caccgggcgg 1380 0 gagctggccg caacaacagg gaccagcgcc ggaggcagcg gagccgggac cacgggtgtg 1386 0 atattaattg cgggggcagg cttactgacc tgcgcaatct tccgctcctg ccactcccca 1392 0 cgaacagcaa gtgcgcgggg caggttctta aagacaatat cgccggggcc aatgcgtttt 1398 0 tttgtctcat caaccagctt acctgtgtta tcagcaattt tgctgagtct gcgtagcgtg 1404 0 ccggtattgc tgtctgtgag aggtttgttg tctttgggtt tatcatctcc ggtgccattg 1410 0 ctatttcccg cagacttcgg cggattgatt ttcgcaatgt ctccctgaaa cagagcaacc 1416 0 ttgtcctgaa gaatggccgc acgttgtgcg tcttcgattt tcttgcgcgc cctttccgct 1422 0 tcatccggaa gcacaccgag tttttcaagt atccacgcca gcgtatccag caacattttt 1428 0 gcaggcgtca gaacaagctg taacgcacca ccaagaacgt taccgaatac ctcgccagca 1434 0 ctggtacatt tatccagcgt ttccttgctg gactccatcg gtgacagcag cgatttaaac 1440 0 cagttaaaca cctggctgaa ccgcttccga ttacgtcaaa aacagggcca aaccgttcaa 1446 0 aggtgtcgcg caacggggtc agcctttcca taatcccgct gaacaccccg gcaaagaaag 1452 0 ccctgatagg atcccagtat ttccagataa gaacggcagc tccggcaagc gcagccacga 1458 0 taagaccaac cggactgaac aacgccccga taacgcctcc cagtaaagaa acggaacccg 1464 0 tcaccattcc ccatagcgca ggtaacaccc tgacgacatt cattgaccgg gtaagaatgt 1470 0 caaaaccaag acgcagggtg gccagcttcc cgtaaagcac cccaataacc agcgacaacg 1476 0 agccaatcgt tgcagtcatt gccagcaacg caccgcctgc tatcagtagc tggcgcgtca 1482 0 gtaccggatg ggcctgcgcc agcgaggtga ttttttcaag cacccgcgtg agccactgcg 1488 0 tgacagaacg cagcggaccg tcaaccagat cactgatgcg aatacgaaga ccttcccatg 1494 0 cgctgtcgag atttttcagg tccccatcaa gattatcagc cattactttt gcgacgcgat 1500 0 cggcctctcc ccttgccccc tgcaattctc tggtcagttt ttgcagctct cctgaaccag 1506 0 ccgccgcaac aagcgtctgc aaaccaacga acgcctcttc tccggcgatg tccttgaaga 1512 0 aggagacctg gtccacctgt ccgtattttt gtgtcgcctt atagagatca agcagcacat 1518 0 cctccatcgg gcgcattttg cctctggcgt cagcaactga cacccccagc tctttcagtg 1524 0 catcagccgc agcttttggc ggtgatgcaa ggcgggacag acttgcgcgc atggccgtgc 1530 0 cagcatcgct tccgcgaaga ccattattgg caagcatccc ggccatggcc gccgcttctt 1536 0 caagactgat accaagtttt gcggcaaccg gaccggtata cttcatggtt tcgcccagcg 1542 0 cgcgtaaatc agtattggtc cgggtaaatg ctgctgtcag cgtatcgccc acccggtcca 1548 0 tttgatcggc tgtcaggttg aactgtgtga ggatattgga gcctatatca gccgtctcgc 1554 0 cgagttcgac gccacctgcc agcgccatat taagaacacc gggcaatgcg gcctgaatgg 1560 0 cctgcggagt aaaaccagcc attgccagaa agctctgccc actggcggca tcactcgcag 1566 0 taaactgtgt ttcagcaagt tttaacgcct gctcacgcag cgccttaaac tgcgggctgt 1572 0 ttttgtcgat tcgcgtcagt gcctgaacgc gggacatctc tttgccgaac ccgatcgcag 1578 0 gctgcaaaaa acgcccggca gcatagccgc ccgccgctgc cgcaccaatt gccagcgcac 1584 0 cacctgtttt cagttttccc gcggtttcct gcgcgtgcga ataccgctca cgcgcctgcg 1590 0 ttacacgcgc aagcgcctgc cgttcgcgtt caagctggtt gttgtattgt tcggtgcgtc 1596 0 tgatggcctg ctgaatggtg ttatcgctgc ctgtcaggga aatgccgtgg cgtttcagct 1602 0 ctccgccaag ttccctcatt ttctgaattt cccgtgtgcg cgattcattc aggcgttcaa 1608 0 gccgggtgct taactgctgc atcagctttt gttgtttttc gctgagcact gtacccgtgc 1614 0 gttgtaactg attaagggcg ttaagctggc gtcgtgcttt cacgatgcca gcatccgctt 1620 0 tactgacagc gtcgcgggcg cgctcaaatg atcgcgcctg acgctcgaga tttttgatcg 1626 0 ccccctgcgt tcgctggatg gagtcaccaa actgccccat caggcggcgt gcgttttcgg 1632 0 caggtcgggt cagcctgtca acggcgctga aagcgacccg gatatcaaga gtcttcattg 1638 0 tctgcattcc cgctgcgaag tgccgcccgc tcacgccagc taaccacttc gccgggcgtc 1644 0 atcatgaaga tttcggcggg cgaccagtta aaaataacgg caatatctgc cacaaagtct 1650 0 tctatgtgct caaagcacac aaccgtgatc aggcttccgt cgcctgttcg ttcttcccgc 1656 0 cagagtccgc accgctcaaa aaatttacgg caaccacaca taactgaata aagtcacggg 1662 0 atgccatttt tttgatcgtc acttcatcca gtcgcggtga tgtcacgcgt gacagcagcg 1668 0 taaacatgga ttccgctttc agattcagca catcagacag cgacaaatct cgcagagatc 1674 0 cagcctgctc aatagccccg gtgatctcca catacgtgat tttttcgccg cctcgctcaa 1680 0 ttggttgggt aagttttaca ccacgctcac tggtttcttt cacagtgtca gtaactaccg 1686 0 tgttttcggt atcgatgttt ttcgtctctt tcatcaggaa actcctttca gtcagaggcg 1692 0 acgcactgcg ccgcctgcat attacttatc agccaagccc aagcgcggaa cggatgcgat 1698 0 cgggcacaat gtccttgccg tccttccggt aaatgaagtt cagcaggtca atctcccaca 1704 0 acgggcgatc gttaacactc agcttgtagt aggtgttttt aatggcgtaa gtgtgtgatg 1710 0 tggcttcgcc ctgtttggct tcccccatat caatttccgt cacacgtccg cgcatttcga 1716 0 cttcatacag gtcgctttca tcatcggtgt agtattcccc cgcaaaacgc agtagcgtgc 1722 0 cgtcaatcgt gccgccatac ttcaggaaca gctcacgaac tgcgcccccc atgacaaagc 1728 0 tcgcatcaag cgcggagtcg tccaggccga ggtcaatact taccgcaccc atcatgccac 1734 0 caccccggta gctgtcggtt ttgcgcgtca gtttaggcag ggtgacggac gtcaccttac 1740 0 ccacttcgtt ttcaccatcc acaaacagcg taaaaaagcg aagatgtttt ggtacagcca 1746 0 tcaggcacct cccagcaccg caaatgcggg accaaagaat tcatcagtaa acgactggta 1752 0 aagctccatg tcttccagcg gaggaacggg cgtatatttg tagcgaatac gcacacgccc 1758 0 ctgacgtaaa ttcgtggtgc tgttatcctc gatgtcatac cagcactccg cgccaatcag 1764 0 tttcccggca gtaaccagtg aatccagttt tgccctgatg gcactgataa catccttcac 1770 0 gttcgcaggt gtcagtggac tgtcgatggt ttcaaactgc gcttccgcaa ttgaatcagc 1776 0 cagcacctgt gcggttcggg tatacacctc aaagatgtag gcgttcgttt ccggtgtgcg 1782 0 gttgccccag aagcggaacc cgttgcgacg aataatggtc gtgatttctt tgttgttgag 1788 0 gctgttggca tcactgtctt cggcctgcaa cgaccagaac acatgcctcg acatcccaag 1794 0 cacattttta accggaacgt tggacagcga tttgtgccag ccctgctcat ggtcaatgta 1800 0 cgcacgaagg ccgcacgcat aagcaggcgc ggggaacgtt tcgtttttgc cacttttcag 1806 0 gttgtaggcg atgaagtcag gccataagag catcacctca cgttcgttga atttctggcg 1812 0 gtaggtaatc gcctcagcca tcgtgttaca accatgacat gtggcataca caaacgcgcg 1818 0 cagtttaccc gcaatcacgc acagggattt tgttaccgcc tccgtgtcca gctccggcgc 1824 0 ggccagaata cgcggacggt atccgatgct ttcatcctgc tctgcaacaa gcagcgcata 1830 0 catccccgta tagctgccgt cagattcaga accaccgata accagttgat cctgcgtctt 1836 0 accgccttct tctttgtgtt cagccacgcg aacgacgatc acttttgtgc tcacctggtc 1842 0 tgcgatagcc ttaagcgcac gataaagcgt ccccgtagtc ccgcattttc ccagcacgtc 1848 0 attgacgcgg gtcagcagtg tgggcttgtt cagcgggaac agctccgcgt ccgcatcatc 1854 0 tgccgttgcc acgataccga taacactgga atcaacatca ttaatcgctg ttaccaggtc 1860 0 ggtactttcc gtaacacggg caccatgaaa acgagtttca ctcatagctt cagccccttg 1866 0 tatccgttaa atgattcggc aacaatcatc acccaccacg cgcgtaatct cacccctgcg 1872 0 ccgttctccc gccacggcga caacaaaaag cagtaacccc ctccgcacgc acatgcgacc 1878 0 atgccgcaca gggagggaac agatgaccga caccaccatg caattgctca gtcagggcac 1884 0 agaccacgtg aaagtgccgg attttgatat tctcgcggag ggtaaaacgc tgtcaggcgt 1890 0 ggcagagcgc ctgatgagcc tgtcactgac cgacaaccgg ggatttgagg cggaccagct 1896 0 caccatcacg ctggatgatg cagatggtca gttgcagcta ccgccacggg gcgcgcgcct 1902 0 gacggttctc attggctgga aaggagaacc gctgacagaa aaaggcactt gtagattcaa 1908 0 tctgtcaatg caacacccct ttcaattatc tctttcggtg ttttgaactt cagtgtcttt 1914 0 ctcggtctgt tgtttagctg agcagcaacc agatcttcat gttgagtata ttgggcaaga 1920 0 catgtctttt taggaaagta ctgccgaatt agcccatttg tgttctcatt tgttccccgc 1926 0 tgccaaggac tctgaggatc gcagaagtaa actttaacgc cggtgctgac agtaaattct 1932 0 agatgtctgg ccagttccat tcctctgtcc catgtcagtg attttctgag ttctgacggt 1938 0 aaactcagga atttgtcggt aagagcctga tttactgaga cagaatcttt gcccctgagt 1944 0 ctgaggatga tcgtataacg tgattttcgg tctacaagtg tggctatatg agagtttttt 1950 0 gtacctgaga ctaaatcgcc ctcccaatgc cctagagagc gtctgttatc gatatttcgg 1956 0 gaacgttcgt gaattggtgt tccgttcact atgttaatcg tacctctttc gcctttgcgg 1962 0 gtatgacgcc tgccatggcg aaggctatgc gaccgtcgca gatgctgtat attcaggtgg 1968 0 tgtagcgctt cacggctacg aaagtacagc gttttataaa ttgtctcagg tgatattcgc 1974 0 agcgtttttt gacgtggttt tgttcgcctt aaccatcctg atatttgctc tggagaccat 1980 0 ttcatctcca gcttttccag aacaagcttt cgcaatggta aattttgatc cagtaagcac 1986 0 ggttttggcc ttttcgccat tctgttggct cggttattag catcaacagc tttgtaatag 1992 0 cgtctgcccc gattacgctg aacttcacgt gagatcgtcg aaggactgcg attcagcgca 1998 0 gtagctatcg cacgaatgct cattttggct gacaaaccag ctcgtatctc ctcgcgctca 2004 0 gacagtgtca ggtgagctac agcccgctta cgctcatggg gttttatgcc gccagtatcc 2010 0 cttaacatag tgaagatcgt tccgggtttt gaacccagga tattcgctat ttcactgaag 2016 0 cctgttccgt tcttccatag ttccaaacct ccgcaacccc atgttttcac ataactgttg 2022 0 cgttgaccaa ttgaatctac acttacattg ttgatgaaat cgctcacgaa ggaccaccgg 2028 0 acaggctttc agccagaagc gcagattttc gggatgtgaa ccgttaacgg cacataatgc 2034 0 tcgcacaaca aacctgttaa aagagattac tcagcattct cctgcttcca ttgccggatc 2040 0 atttcatcgg taacatcacc ctcataacat accacgtcat accctccatt acggctatat 2046 0 gcactgcgtc caccacatct actaccattc cttgcatgat tataaggaca cgcacaattg 2052 0 cctggataag attcaatgga ttctttaatt atttcttttt tgatctgagc atcagacttt 2058 0 cctgttgctg catatccact aaaagatact aaacaaaggc agattgccat taataaacca 2064 0 catcgcatac cgatacactc aattactaac caatcatagc ccacatcata aaatcgagat 2070 0 gaggagcaca atacctttaa caagaaggtg tcataacgat aatatgtcgt gcaattcatc 2076 0 aaaaaaaaga tctatatcaa agagatagaa ctcttatcag tgcttcagac atcggcattc 2082 0 gaggcagcag aaaaacagta aatctgacga atttgccttt tcccaagatg ttgtcagatt 2088 0 aaaaagatag attagcgcag gtacctgttg gtggattgca ggaggaaaaa taaagtcgag 2094 0 tggaaaaatc ccagaaaaat ttttgtttaa cagaggtcct ggttcactat gcgaaatacg 2100 0 gaggagctgc agaagaattc tgcttcatcc ttagagttta aacagcacgt gcactaccat 2106 0 tgtttctgca tatcgccaca ccatcgccac tctaccgcca ttgcacaaaa tacaaatacg 2112 0 <210> 1158 <211> 334 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(228..1229) <400> 1158 Met Ser Val Arg Lys Ile Pro Ser Gly Lys Trp Leu Cys Glu Cys Tyr 1 5 10 15 Pro Tyr Gly Ala Ser Gly Lys Arg Ile Arg Lys Gln Phe Ala Thr Lys 20 25 30 Ser Glu Ala Leu Ser Tyr Glu Arg Arg Leu Met Asn Ser Arg Val Gly 35 40 45 Asp Glu Phe Gln Asp Gly Ser Gly Pro Arg Leu Ser Glu Leu Ile Ala 50 55 60 Arg Trp Phe Glu Met Tyr Gly Lys Thr Leu Ser Ser Gly Ala Glu Arg 65 70 75 80 Lys Val Lys Leu Glu Ala Ile Cys Ser Arg Leu Gly Asp Pro Phe Ala 85 90 95 Ser Gln Phe Asp Lys Asn Met Phe Ala Thr Tyr Arg Glu Arg Arg Leu 100 105 110 Ser Gly Glu Trp Asn Pro Lys Gly Lys Lys Lys Leu Ser Glu Ala Thr 115 120 125 Val Asn Arg Glu Gln Ser Tyr Leu His Ala Val Phe Ala Glu Leu Lys 130 135 140 Arg Leu Gly Glu Trp Ser Gly Glu Asn Pro Leu Thr Gly Ile Arg Lys 145 150 155 160 Phe Arg Glu Glu Glu Lys Glu Leu Ala Phe Leu Tyr Val Asp Glu Ile 165 170 175 Glu Arg Leu Leu Ile Ala Cys Asp Glu Ser Arg Asn Lys Asp Leu Gly 180 185 190 Val Val Val Arg Ile Gly Leu Ala Thr Gly Ala Arg Trp Ser Glu Ala 195 200 205 Glu Gly Leu Lys Gln Ser Gln Val Leu Pro Gly Arg Ile Thr Phe Val 210 215 220 Lys Thr Lys Gly Lys Lys Asn Arg Thr Val Pro Ile Ser Pro Gln Leu 225 230 235 240 Gln Ala Met Leu Pro Lys Lys Arg Gly Ala Leu Phe Ser Pro Cys Tyr 245 250 255 Glu Ala Phe Asp Ala Ala Ile Lys Arg Ala Lys Ile Glu Leu Pro Asp 260 265 270 Gly Gln Leu Thr His Val Leu Arg His Thr Phe Ala Ser His Phe Met 275 280 285 Met Arg Gly Gly Asn Ile Leu Val Leu Gln Lys Ile Leu Gly His Ser 290 295 300 Asp Ile Lys Met Thr Met Arg Tyr Ala His Phe Ala Pro Gly His Leu 305 310 315 320 Glu Ala Ala Val Glu Leu Asn Pro Phe Asp Asn Arg Gly * 325 330 <210> 1159 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1235..1582) <400> 1159 Met Lys Val Lys Lys Val Gln Leu Leu Val Thr Phe Leu Ser Met Phe 1 5 10 15 Ser Phe Ser Ala Val Ala Met Pro Phe Lys Thr Ile Glu Arg Glu Ser 20 25 30 Phe Asn Gly Val Trp Pro Phe Asn Thr Asp Glu Val Gln Leu Gln Cys 35 40 45 Leu Asp Gly Asn Pro Tyr Val Met Asn Phe Asp Asp Asn Lys Leu Tyr 50 55 60 Ala Leu Thr Gly Leu Ala Arg Ile Lys Gly Lys Thr Phe Gly Ala Leu 65 70 75 80 Pro Leu Asp Asn Asn Asn Pro Phe Trp Leu Asp Asn Asp Ala Ala Pro 85 90 95 Gly Leu Lys Lys Ser Leu Gly Asp Val Thr Lys Ala Ala Phe Asp Leu 100 105 110 Cys Asp Lys * 115 <210> 1160 <211> 217 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1612..2262) <400> 1160 Met Ala Val Asn Ser Asn Gly Ser Asn Asn Arg Val Ala Gly Arg Asp 1 5 10 15 Phe His Glu Lys Asn Ile Gln Ile Glu Arg Tyr Asp Gly Ser His Thr 20 25 30 Val Asn Ile Ala Ile Pro Ser Asn Asn Asp Asp Asp Asp Arg Pro Leu 35 40 45 Leu Lys Ala Gln Arg Lys Glu Leu Asn Ser Leu Val Ala Ala Ile Ala 50 55 60 Glu Ala Ser Asn Thr Glu Ala Phe Ile Ile Trp Gln Lys Val His Ala 65 70 75 80 Glu Ile Gly Val Ala Gly Ile Asp Asp Met Thr Val Asn Gln Tyr Lys 85 90 95 Thr Ala Glu Ser Phe Leu His Ala Met Leu Glu Arg Cys Lys Asp His 100 105 110 Asp Ala Cys Lys Ala Leu Val Ser Leu Leu Leu Arg Asn Ser Glu Asp 115 120 125 Cys Gly Leu Arg Gln Lys Leu Leu Arg Tyr Cys His Ile Asn Phe Gly 130 135 140 Thr Gly Arg Leu Asn Asp Leu Thr Arg Ser Gln Leu Gln Ser Ala Leu 145 150 155 160 Ser Trp Leu Glu Gln Gln Ser Ala Ser Ser His Ile Glu Ser Ser Thr 165 170 175 Leu Pro Glu Val Arg Leu Arg Ala Ser Glu Leu Ile Arg Leu Tyr Pro 180 185 190 Lys Glu Ile Ile Phe Phe Ile Cys Val Gly Val Leu Val Gly Gly Val 195 200 205 Ile Ser Arg Ala Phe Phe Asn Leu * 210 215 <210> 1161 <211> 135 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2278..2682) <400> 1161 Met Lys Asn Asp Ile Gly Arg Arg Leu Arg Glu Glu Arg Glu Arg Leu 1 5 10 15 Gly Leu Ser Gln Val Ala Met Ser Asp Ile Gly Gly Val Lys Lys Leu 20 25 30 Thr Gln Leu Arg Tyr Glu Lys Gly Asp Ser Phe Pro Asp Ala Ala Tyr 35 40 45 Leu Ala Ala Leu Ser Arg Phe Gly Leu Asp Val Gln Tyr Val Val Leu 50 55 60 Gly Ile His Ser Pro Glu Thr Tyr Asn Asp Asp Glu Gln Glu Leu Ile 65 70 75 80 Thr Arg Phe Arg Ala Ala Ser Leu Asp Val Lys Asn Ala Val Ile Gly 85 90 95 Ala Leu Lys Gly Ala Ile Ser Glu Lys Glu Thr Gln Pro Ser Gly Arg 100 105 110 Glu Leu Asn Ile Ser Gly Gly Asn Asn Arg Ile Ala Gly Arg Asp Tyr 115 120 125 Asn Glu Thr Lys Gly Arg * 130 <210> 1162 <211> 46 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2772..2909) <400> 1162 Met Arg Ala Met Leu Glu Asp Glu Arg Cys Ser Leu Ala Ala Ile Ser 1 5 10 15 Ser Met Thr Ala Arg Ser Ser Arg Asp Ser Arg Ser Ala Ser Leu Gly 20 25 30 Pro Val Ala Val Leu Arg Gly Met Arg Asp Leu Val Ser * 35 40 45 <210> 1163 <211> 68 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2981..3184) <400> 1163 Met Ser Gly Ile Thr Ile Asn Ile Asn Val Asn Ala Pro Tyr Val Ser 1 5 10 15 Leu Gln Lys Tyr Ala Glu Ile Thr Gly Ile Pro Leu Asn Thr Cys Lys 20 25 30 Lys Met Leu Ala Asp Gly Arg Ile Ile Ile Arg Pro Lys Arg Ala Lys 35 40 45 Met Glu Lys Pro Glu Val Asn Leu Val Ala Met Leu Lys Asp Ala Leu 50 55 60 Ala Asn Ser * 65 <210> 1164 <211> 117 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3206..3556) <400> 1164 Met Lys Lys Asn Ala Asn Asn Pro Tyr Ser Lys Phe Arg Asn Gly Val 1 5 10 15 Glu Arg His Val His His Val Ala Thr Ser Ala Ser Arg Ser Asn Ser 20 25 30 Arg Tyr Asn Leu Asn Glu Thr His Ala Thr Pro Asp Gly His Ala Val 35 40 45 Lys Gln Ile Gly Glu His Ala Trp Leu Ile Glu Lys Ala Gly Ile Val 50 55 60 Val His Lys Cys Pro Arg Asn Pro Phe Thr Gly Asn Arg Ile Phe Ala 65 70 75 80 Leu Asn Cys Gly Asp Asn His Phe Gly Gln Asp Phe Thr Leu Tyr Glu 85 90 95 Ala Leu Arg Thr Val Asp Arg Leu Leu Arg Gly Gln Ser Phe Ile Lys 100 105 110 Gln Ala Asp Leu * 115 <210> 1165 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3567..3845) <400> 1165 Met Thr Lys Glu His Ala Gln Gly Val Phe Ile Arg Phe Ile Asp Phe 1 5 10 15 Arg Gly Glu Leu Leu Leu Arg Ala Ser Ala Ile Asp Gly Ile Val Pro 20 25 30 Ser Glu Lys Asn Ala Ala Thr Tyr Val Tyr Leu Asn Gly Thr Arg Leu 35 40 45 Thr Val Glu Leu Pro Tyr Gln Thr Val Arg Glu Ile Ile Ser Glu Ala 50 55 60 Glu Lys Ala Arg Gln Val Asn Gly Asp Glu Pro Tyr Ile Glu Ile Ile 65 70 75 80 Cys Met Asp Ser Glu Ala Glu Ile Gln Lys Ala Asp * 85 90 <210> 1166 <211> 81 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3857..4099) <400> 1166 Met Gly Lys Glu Tyr Lys Thr Leu Ile Asn Lys Ala Pro Glu Arg Phe 1 5 10 15 Tyr Phe Arg Leu Ser Ala Ser Gly Ala His Ala Glu Arg Ala Ala Arg 20 25 30 Asp Ser Leu Thr Arg Ala Ile Arg Ser Leu Tyr Asp Val Ala Phe Tyr 35 40 45 Ala Asp Asp Leu Asp Ala Leu Asn Glu Leu Ser Glu Leu Ile Cys Ala 50 55 60 Ala Glu Cys Gly Glu His Ile Glu Pro Tyr Lys Leu Gly Asn Ile Ala 65 70 75 80 * <210> 1167 <211> 139 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4302..4718) <400> 1167 Met Asn Ala Lys Glu Lys Asn Ile Ile Asn Thr Leu Lys Ile Val Ser 1 5 10 15 Ala Glu Gln Asp Lys Leu Ser Arg Ala Ala Gln Lys Asp Asn Gln His 20 25 30 Met Ala Ala Leu Tyr Ala Leu Thr Ile Ala Ile Ala Thr Pro Glu Ala 35 40 45 Ala Lys Val Ile Glu Glu Gln Ser Lys Glu Ile Asp Thr Leu Lys Thr 50 55 60 Gln Ser Thr Val Ala Ala Met Asn Pro Ser Ser Ile Gly Arg Cys Ile 65 70 75 80 Tyr Ile Leu Gly Ser Ala Met Met Leu Gln Tyr Thr Ile Ile Ala Glu 85 90 95 Leu His Gly Lys Tyr Leu Ile Thr Pro Tyr His Thr Lys Glu Ser Glu 100 105 110 Leu Leu Thr Asn Leu Arg Leu Ile Glu Arg Ser Gln Ala Val Phe Ile 115 120 125 Asp Asp Ala Gln Arg Ala Val Phe Asn Ala * 130 135 <210> 1168 <211> 68 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4742..4945) <400> 1168 Met Ala Ile Lys His Phe Pro Val Val Arg Phe Thr Ser Arg Gly Arg 1 5 10 15 Glu Tyr Glu Val Asp Glu Arg Leu Ile Thr Thr Ile Asp Lys His Arg 20 25 30 Ser Glu Lys Asp Ala His His Ile Tyr Leu Thr Asp Gly Thr Tyr Phe 35 40 45 Cys Ala Thr Asn Val Ala Arg Val Asn Leu Ile Arg Gln Val Gln Glu 50 55 60 Pro Arg Arg * 65 <210> 1169 <211> 89 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4942..5208) <400> 1169 Met Thr Ile Leu Asp Tyr Ile Ala Thr His Pro Gly Cys Ser Gly Gly 1 5 10 15 Glu Ile Ala Ala Ala Leu Asn Thr Pro Thr Thr Ala Ile Asn Ala Glu 20 25 30 Leu Arg Arg Leu Trp Arg Gly Gly Leu Val Ile Arg Thr Asn Arg Ser 35 40 45 Thr Gly Gly Arg Ala Arg Lys Thr Gly Gly Gln Ala Ser Tyr His Val 50 55 60 Asn Pro Met Pro Phe Gly Cys Ser Asn Pro Leu Thr His Met Phe Asn 65 70 75 80 Gln Leu Leu Lys Glu Ala Arg Ala * 85 <210> 1170 <211> 100 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5205..5504) <400> 1170 Met Ser Thr Ile Asn His Gln Lys Leu Arg Glu Leu Ala Phe Ala Leu 1 5 10 15 Gln Arg Met Ala Thr Pro Gln Lys Leu Leu Ala Phe Arg Ala Met Leu 20 25 30 Ser Pro Ser Ala Val Leu Ala Leu Leu Asp Gln Leu Glu His Ala Arg 35 40 45 Thr Thr Ala Pro Ala Ile Arg Leu Thr Leu His His Glu Ile Ala Asp 50 55 60 Phe Cys Ala Thr Leu Gly Ala Pro Gly Glu Pro Glu Thr Pro Glu Ala 65 70 75 80 Met Gln Gln Glu Leu Leu Gln Arg Ile Asp Asn Val Phe Asp Phe Phe 85 90 95 Leu Asn Gln * <210> 1171 <211> 206 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5516..6133) <400> 1171 Met His Thr Gln Lys Asn Arg Leu Pro Cys Arg Asn Arg Ser Gly Tyr 1 5 10 15 Ile Ser Ala Ala Pro His Lys Thr Gly Ala Gly Ile Leu Asn Pro Ile 20 25 30 Gln Ser Lys Ala His Asn Arg Ala Ser Gly Phe Phe Val Arg Thr Val 35 40 45 Leu Pro Arg Leu Phe Arg Val Arg Ile Met Ala Gly Arg Thr Gly Pro 50 55 60 Thr Ser Val Gly Pro Asp Ser Leu Leu Ser Gly Val Glu Asn Pro Val 65 70 75 80 Arg Leu Ala Ser Pro Arg Phe Ser Thr Leu Asp Gly Glu Leu Phe Leu 85 90 95 Ser Pro Ser Lys Glu Ala Thr Pro Trp Gln Thr Ala Asn Ser Thr Ala 100 105 110 Leu Ser Arg Ser Val Val Thr Ser Arg Leu Lys Ser Thr Ala Asp Phe 115 120 125 Pro Ala His His Ala Ser Arg Lys Ser Cys Thr Ser Ile Cys Cys Met 130 135 140 Ser Ala Ala Thr His Tyr Gln Thr Phe Ile Pro Pro Leu Phe Ser Ala 145 150 155 160 Ile Trp Arg Met Ile Cys Thr Ser Phe Asn Ser Ser Ser Ser Ser Lys 165 170 175 Thr Asn Ser Ile Asn Ser Cys Ser Gly Pro Phe Leu His Leu Ala Ala 180 185 190 Gly Gly Leu Arg Thr Ser Val Thr Arg Gly Leu Pro Gln * 195 200 205 <210> 1172 <211> 77 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5827..6057) <400> 1172 Met Ala Asp Arg Lys Gln His Arg Ala Ile Ala Glu Arg Arg His Ile 1 5 10 15 Gln Thr Glu Ile Asn Arg Arg Leu Ser Arg Ala Ser Arg Val Ala Gln 20 25 30 Ile Met His Ile Asn Met Leu His Glu Arg Ser His Ala Leu Ser Asn 35 40 45 Ile Tyr Ser Ala Ser Val Phe Ser Tyr Leu Ala Asp Asp Leu His Glu 50 55 60 Phe Gln Gln Leu Ile Gln Gln Gln Asn Lys Leu His * 65 70 75 <210> 1173 <211> 122 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6130..6495) <400> 1173 Met Ile Leu Ala Asn Asp Phe Leu Glu Tyr Leu Leu Asn Thr Glu Arg 1 5 10 15 Asp Leu Ala Ala Arg Val Arg Asp Arg Tyr Asp Met Tyr Leu Lys Ser 20 25 30 Leu Pro Val Pro Gln Leu Ala Asp Gly Lys Ile Val Ile Asp Gly Arg 35 40 45 Tyr Met Ile Asp Ser His Glu Gly Asn Tyr Arg Leu Tyr Arg Ile Glu 50 55 60 Gly Gly Thr Pro Ser Val Ile Gly Ile Tyr Gln Arg Pro Ser Ser Ala 65 70 75 80 Ile Val Asp Val Ile Ala Asp Ser Ile Arg Ile Thr His Arg His Ala 85 90 95 Asp Thr Glu Asp Thr Val Leu Glu Ile Gln Arg Leu Ala Thr Ala Cys 100 105 110 Arg Asp Thr Leu Asn Gly Met Thr Lys * 115 120 <210> 1174 <211> 895 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6640..9324) <400> 1174 Met Ala Asp Ala Ala Phe Ser Ala Thr Pro Leu Gly Asn Leu Ile Asn 1 5 10 15 Lys Ser Leu Asp Ala Gln Glu Lys Gln Asp Lys Thr Ile Thr Leu Ala 20 25 30 Gly Asp Ala Arg Lys Gln Ala Arg Gly Ala Val Asp Glu Ala Met Ala 35 40 45 Ser Leu Arg Leu Leu Pro Ser Tyr Leu Arg Asp Pro Leu Ile Arg His 50 55 60 Leu Ser Phe Leu Arg Lys Lys Gln Glu Ala Asp Arg Gln Lys Gly Lys 65 70 75 80 Lys Ser Trp Gln Ala Glu Arg Tyr Ala Arg Gly Asn Leu Arg Lys Ile 85 90 95 Phe Glu Arg Leu Glu Arg Thr Asp His Arg Trp Leu Thr Gln Gly Tyr 100 105 110 Arg Ser Leu Ala Gly Arg Glu Arg Leu Asp Asp Leu Leu Tyr Leu Pro 115 120 125 Gln Leu Asn Lys His Gln Ile Gln Thr Leu Ala Thr Met Thr Ala Ala 130 135 140 Met Phe Ser Ser Thr Phe Glu Lys Leu Cys Asp Gly Phe Gly Ala Thr 145 150 155 160 Asp Gly Glu Leu Thr Met Asp Val Thr Leu Lys Ala Tyr Gln Met Leu 165 170 175 Ala Arg Met Ala Leu His Leu His Ala Met Pro Pro His Tyr Asp Ala 180 185 190 Leu Thr Thr Asp Lys Asp Arg Arg Asn Glu Pro Asp Thr Glu Leu Leu 195 200 205 Pro Gly Ala Ile Leu Arg Leu Thr Cys Ala Glu Trp Trp Lys Arg Lys 210 215 220 Leu Trp Leu Leu Arg Cys Glu Trp Arg Glu Glu Gln Leu Arg Ala Ala 225 230 235 240 Cys Leu Val Ser Arg Lys Thr Ser Pro Tyr Leu Ser Gln Asp Ala Leu 245 250 255 Ser Glu Phe Arg Ala Gln Arg Glu Lys Thr Arg Asp Phe Leu Lys Ser 260 265 270 Phe Met Leu Glu Asn Glu Asp Gly Phe Thr Ile Asp Leu Glu Thr Val 275 280 285 Tyr Tyr Ala Gly Val Ser Asn Pro Val His Arg Lys Ala Glu Met Met 290 295 300 Ala Thr Met Lys Gly Leu Glu Leu Leu Ala Glu Ala Arg Gly Asp Lys 305 310 315 320 Ala Val Phe Leu Thr Val Thr Cys Pro Ser Lys Tyr His Ala Thr Thr 325 330 335 Glu Asn Gly His Pro Asn Pro Lys Trp Asn Gly Ala Thr Met Arg Asp 340 345 350 Ser Ser Asp Tyr Leu Val Asn Thr Phe Phe Ala Ala Val Arg Lys Lys 355 360 365 Leu Asn Arg Asp Gly Leu Arg Trp Tyr Gly Ile Arg Thr Val Glu Pro 370 375 380 His His Asp Gly Thr Val His Trp His Met Met Val Phe Ala His Pro 385 390 395 400 Glu Glu Ile Asp Thr Ile Val Ser His Thr Arg Asp Ile Ala Ile Gln 405 410 415 Glu Asp Arg His Glu Leu Gly Asp Asp Ile Thr Pro Arg Phe Lys Ala 420 425 430 Glu Tyr Val Asp Gly Ser Lys Gly Thr Pro Thr Ser Tyr Ile Ala Thr 435 440 445 Tyr Ile Gly Lys Asn Leu Asp Ser Arg Ala Val Asp Gly Ile Asp Pro 450 455 460 Lys Thr Gly Lys Pro Arg Val Asp His Glu Thr Gly Lys Ser Met Thr 465 470 475 480 Glu Ser Val Glu Arg Ala Ile Gly Trp Ala Arg Leu His Arg Val Arg 485 490 495 Gln Phe Gln Phe Phe Gly Ile Pro Ser Arg Gln Val Trp Arg Glu Leu 500 505 510 Arg Arg Leu Ala Ser Gln Met Ala Arg Asn Pro Glu Gly Pro Gln Arg 515 520 525 Leu Lys Asp Asp Ala Met Asp Ala Val Leu Ala Ala Ala Asp Ala Gly 530 535 540 Cys Phe Thr Thr Tyr Ile Glu Lys Gln Gly Gly Val Leu Val Pro Arg 545 550 555 560 Lys Asp Tyr Leu Ile Arg Thr Ala Tyr Asp Leu Ala Asp Glu Leu Asn 565 570 575 Asp Tyr Gly Glu Gln Ser Val Gln Ile Tyr Gly Ile Trp Ser Pro Leu 580 585 590 Ile Gly Glu Ser Ser Arg Val Cys Thr His Pro Asp Asn Trp Lys Leu 595 600 605 Val Arg Arg Lys Pro Gly Val Glu Asp Ser Ala Arg Glu Asn Gly Phe 610 615 620 Asp Leu Gln Gly Gly Pro Ala Ala Pro Trp Thr Arg Gly Asn Asn Cys 625 630 635 640 Pro Arg Val Gln Glu Thr Asp Asn Asn Gly Thr Glu Gln Pro Glu Glu 645 650 655 Arg Pro Ala Pro Trp Pro Gln Leu Pro Asp Gly Val Asp Val Asn Glu 660 665 670 Trp Met Arg Ser Leu Lys Arg His Glu Arg Arg Ala Leu Met Arg Ser 675 680 685 Leu Arg Asp Lys Gln Ala Lys Asn Ser Ser Asp Glu Met Gln Ser Trp 690 695 700 Thr Gln Ser Arg Lys Gln Gln Arg Pro Leu Pro Asp Asn His Glu Leu 705 710 715 720 Leu Ala Lys Glu Trp Arg Glu Ser Ala Glu Ser Leu Gly Leu His Ile 725 730 735 Gly Glu Gln Gln Met Gln His Leu Leu Arg Gly Gly Ser Leu Tyr Val 740 745 750 Asp Gly Ser Ile Ile Ala Pro Gln Gly Phe Glu Ile Val Arg Lys Pro 755 760 765 Asp Thr Arg Pro Asp Ser Arg Ile Thr Gln Leu Trp Gln Arg Leu Ser 770 775 780 Arg Asn His Gly Val Ser Ser Thr Glu Ile Arg His Asn Pro Val Ala 785 790 795 800 Ser Tyr Leu Ala Gln Leu Gly Ala Ser Asp Pro Glu Ala Ala Ala Arg 805 810 815 Leu Ala Ser Thr Leu Gln Gln Asp Gln Asn Thr Met Lys Thr Pro Val 820 825 830 Thr Val Leu Ser Asp Met Leu Arg Ala Ile Arg Asp Ala Glu His Ala 835 840 845 Gln Arg Ile Ser Glu Thr Thr Glu Arg Ala Ser Arg Lys Ala Asp Leu 850 855 860 Leu Arg Gly Gly Leu Thr Ser Gly Asn Lys Lys Gln Thr Glu Thr Gly 865 870 875 880 Leu Thr Asn Pro Val Asn Glu Gln Lys Thr Arg Arg Asp Ile * 885 890 <210> 1175 <211> 320 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9401..10360) <400> 1175 Met Lys Ile Cys Ile Asp Asp Gly Ser Thr Asn Ile Lys Leu Ala Trp 1 5 10 15 Thr Glu Asn Gly Glu Arg Arg Asn Ala Ile Ser Pro Asn Ser Phe Lys 20 25 30 Ser Glu Trp Ser Ala Pro Phe Gly Gly Thr Gln Pro Ala Asn Tyr Met 35 40 45 Leu Asp Gly Val Arg Tyr Gly Phe Asp Pro Val Ser Asp Arg Phe Val 50 55 60 Gln Thr Thr Asp Thr Gln Tyr Gln Tyr Ser Asp Val Asn Val Ile Ala 65 70 75 80 Ile His His Ala Leu Val Lys Ser Gly Ile Thr Pro Gln Glu Val Asp 85 90 95 Val Val Val Thr Leu Pro Leu Ser Glu Tyr Phe Asp Thr Asn Ala Gln 100 105 110 Pro Asp Met Ala Asn Ile Asn Arg Lys Lys Ala Asn Val Met Arg Pro 115 120 125 Val Glu Tyr Gln Asn Gly Glu Ala Phe Thr Ile Arg Asn Val Arg Val 130 135 140 Met Pro Glu Ser Ile Pro Ala Gly Phe Lys Ala Pro Ala Asp Met Ser 145 150 155 160 Pro Phe Glu Ser Leu Leu Ile Val Asp Leu Gly Gly Thr Thr Leu Asp 165 170 175 Val Ala Lys Val Gln Gly Gln Leu Ala Gly Ile Ser Gln Val Phe Cys 180 185 190 Asp Pro His Val Gly Val Ser Leu Met Ala Asp Ala Val Leu Ser Val 195 200 205 Met Ala Thr Asn Gly Met Arg Thr Ser His His Ile Ala Asn Thr Ile 210 215 220 Ile Glu His Arg His Asp Glu Ala Trp Leu Arg Gln His Ile His Asn 225 230 235 240 Asp Ala His Tyr Ala Ser Leu Met Ala Val Ile Arg Glu Lys Glu Glu 245 250 255 Thr Leu Lys Gln Arg Val Ile Arg Ala Leu Ala Val Phe Ser Gly Tyr 260 265 270 Gly Arg Val Met Val Val Gly Gly Gly Ala Glu Ile Val Ala Thr Ala 275 280 285 Ile Arg Glu Ala Cys Gly Val Asn Ala Thr Phe Ile Ala Asp Gly Val 290 295 300 Pro Gln Phe Ala Leu Val Asn Gly Leu Tyr Ala Met Asn Lys Glu * 305 310 315 <210> 1176 <211> 105 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10365..10679) <400> 1176 Met Thr Thr Pro Thr Arg Arg Ile Ser Phe Tyr Leu Lys Pro Ala Ala 1 5 10 15 Val Lys Ser Glu Gln Glu Ala Cys Asn Tyr Leu Asp Ser Leu Pro Ala 20 25 30 Ser Glu Arg Ser Arg Ala Gln Arg Ala Ala Phe Leu Ala Gly Leu Ala 35 40 45 Leu Ile Lys Arg Asn Pro Ala Phe Ala Tyr Trp Met Ala Glu Trp Pro 50 55 60 Glu Asp Asn Leu Pro Phe Asn Thr Val Ser Ile Lys Glu Thr Tyr Gln 65 70 75 80 Ala Asn Gln Pro Ser Gly Val Glu Cys Asn Phe Tyr Lys Ile Lys Lys 85 90 95 Asn Ile Gln Thr Leu Phe Pro Glu * 100 <210> 1177 <211> 230 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10699..11388) <400> 1177 Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro Val 1 5 10 15 Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln Gln 20 25 30 Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln Arg Asp Asp 35 40 45 Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln Val 50 55 60 Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile Arg 65 70 75 80 Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu Ala 85 90 95 Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Val Ser Arg Lys Ala 100 105 110 Val Ser Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg Pro 115 120 125 Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln Gly 130 135 140 Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ser Gly Cys Ile Val 145 150 155 160 Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp Ala 165 170 175 Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Val His His 180 185 190 Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg Leu 195 200 205 Lys Glu Ala Lys Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser Tyr 210 215 220 Asp Asn Val Phe Tyr * 225 <210> 1178 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11388..11714) <400> 1178 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Val 1 5 10 15 Arg Met Val Leu Glu Ser Gln Gly Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Thr Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Pro Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1179 <211> 159 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12345..12821) <400> 1179 Met Asp Ile Trp Arg Leu Leu Arg Glu Lys Lys Gln Arg Asn Arg Asn 1 5 10 15 Phe Leu Phe Trp Trp Arg Leu Ala Asn Glu Met Tyr Ile Asn Gly Asn 20 25 30 Lys Leu His Lys Lys Ala Ala Lys Lys Leu Asn Ser Lys Ile Ile Asn 35 40 45 Lys Phe Gly Cys Glu Ile Gly Leu Gly Ala Asn Ile Gly Lys Gly Leu 50 55 60 Thr Ile Pro His His Ala Gly Ile Val Val His Phe Ala Val Asp Ala 65 70 75 80 Gly Glu Asn Leu Val Leu Arg Gln Asn Thr Thr Ile Gly Gln Ile Asp 85 90 95 Gly Asp Met Pro Ser Ser Arg Val Lys Ile Gly Ser Asn Val Asp Ile 100 105 110 Gly Ala Asn Cys Cys Ile Ile Gly Leu Ser Arg Lys Ile Gly Asp Asn 115 120 125 Val Lys Ile Gly Ala Met Ser Phe Ile Asn Lys Asp Ile Pro Ser Asn 130 135 140 Cys Thr Tyr Ile Thr Lys Lys Ser Gly Val Val Leu Tyr Lys * 145 150 155 <210> 1180 <211> 163 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13074..13562) <400> 1180 Met Met Met Ile Tyr Gly Met Phe Val Phe Glu Leu Arg Thr Leu Pro 1 5 10 15 His Gln Gln Leu Gln Gln Asn Lys Ser Trp Arg His Val Lys Asn Glu 20 25 30 Arg Val Asn Arg Ser Ala Ser Trp Gln Tyr Ile Gly Ala Gly Asp Asp 35 40 45 Arg Ile Val Leu Ser Gly Val Leu Tyr Pro Glu Ile Thr Gly Gly Glu 50 55 60 Val Ser Leu Ser Leu Leu Thr Thr Gln Ala Tyr Thr Gly Arg Pro Trp 65 70 75 80 Pro Leu Ile Asp Gly Val Gly Gln Ile Tyr Gly Met Tyr Val Leu Thr 85 90 95 Gly Thr Asn Thr Thr Arg Ser Glu Phe Asp Arg Tyr Gly Lys Ala Lys 100 105 110 Lys Ile Glu Phe Ser Leu Thr Leu Glu Arg Cys Asp Glu Asp Leu Arg 115 120 125 Glu Arg Leu Gln Ser Ser Ser Phe Ser Asp Met Leu Ser Gly Phe Lys 130 135 140 Asp Lys Val Thr Ser Ser Leu Asn Ser Ala Ala Ser Ser Val Lys Gly 145 150 155 160 Leu Leu * <210> 1181 <211> 279 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13575..14411) <400> 1181 Val Phe Asn Trp Phe Lys Ser Leu Leu Ser Pro Met Glu Ser Ser Lys 1 5 10 15 Glu Thr Leu Asp Lys Cys Thr Ser Ala Gly Glu Val Phe Gly Asn Val 20 25 30 Leu Gly Gly Ala Leu Gln Leu Val Leu Thr Pro Ala Lys Met Leu Leu 35 40 45 Asp Thr Leu Ala Trp Ile Leu Glu Lys Leu Gly Val Leu Pro Asp Glu 50 55 60 Ala Glu Arg Ala Arg Lys Lys Ile Glu Asp Ala Gln Arg Ala Ala Ile 65 70 75 80 Leu Gln Asp Lys Val Ala Leu Phe Gln Gly Asp Ile Ala Lys Ile Asn 85 90 95 Pro Pro Lys Ser Ala Gly Asn Ser Asn Gly Thr Gly Asp Asp Lys Pro 100 105 110 Lys Asp Asn Lys Pro Leu Thr Asp Ser Asn Thr Gly Thr Leu Arg Arg 115 120 125 Leu Ser Lys Ile Ala Asp Asn Thr Gly Lys Leu Val Asp Glu Thr Lys 130 135 140 Lys Arg Ile Gly Pro Gly Asp Ile Val Phe Lys Asn Leu Pro Arg Ala 145 150 155 160 Leu Ala Val Arg Gly Glu Trp Gln Glu Arg Lys Ile Ala Gln Val Ser 165 170 175 Lys Pro Ala Pro Ala Ile Asn Ile Thr Pro Val Val Pro Ala Pro Leu 180 185 190 Pro Pro Ala Leu Val Pro Val Val Ala Ala Ser Ser Arg Pro Val Val 195 200 205 Glu Ala Ile Arg Ser Pro Val Ala Ser Val Pro Ala Thr Ser Arg Asn 210 215 220 Arg Glu Pro Val Ala Ser Gly Phe Gly Gly Glu Ile His Val His Leu 225 230 235 240 His Asn Val Val Thr Gln Asn Pro Arg Glu Leu Ala Lys Leu Val Gly 245 250 255 Glu Met Val Arg Ala Glu Met Glu Arg Arg Ala Arg Ala Arg Arg Gly 260 265 270 Ser Phe Tyr Asp Lys Asp * 275 <210> 1182 <211> 697 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14288..16378) <400> 1182 Met Lys Thr Leu Asp Ile Arg Val Ala Phe Ser Ala Val Asp Arg Leu 1 5 10 15 Thr Arg Pro Ala Glu Asn Ala Arg Arg Leu Met Gly Gln Phe Gly Asp 20 25 30 Ser Ile Gln Arg Thr Gln Gly Ala Ile Lys Asn Leu Glu Arg Gln Ala 35 40 45 Arg Ser Phe Glu Arg Ala Arg Asp Ala Val Ser Lys Ala Asp Ala Gly 50 55 60 Ile Val Lys Ala Arg Arg Gln Leu Asn Ala Leu Asn Gln Leu Gln Arg 65 70 75 80 Thr Gly Thr Val Leu Ser Glu Lys Gln Gln Lys Leu Met Gln Gln Leu 85 90 95 Ser Thr Arg Leu Glu Arg Leu Asn Glu Ser Arg Thr Arg Glu Ile Gln 100 105 110 Lys Met Arg Glu Leu Gly Gly Glu Leu Lys Arg His Gly Ile Ser Leu 115 120 125 Thr Gly Ser Asp Asn Thr Ile Gln Gln Ala Ile Arg Arg Thr Glu Gln 130 135 140 Tyr Asn Asn Gln Leu Glu Arg Glu Arg Gln Ala Leu Ala Arg Val Thr 145 150 155 160 Gln Ala Arg Glu Arg Tyr Ser His Ala Gln Glu Thr Ala Gly Lys Leu 165 170 175 Lys Thr Gly Gly Ala Leu Ala Ile Gly Ala Ala Ala Ala Gly Gly Tyr 180 185 190 Ala Ala Gly Arg Phe Leu Gln Pro Ala Ile Gly Phe Gly Lys Glu Met 195 200 205 Ser Arg Val Gln Ala Leu Thr Arg Ile Asp Lys Asn Ser Pro Gln Phe 210 215 220 Lys Ala Leu Arg Glu Gln Ala Leu Lys Leu Ala Glu Thr Gln Phe Thr 225 230 235 240 Ala Ser Asp Ala Ala Ser Gly Gln Ser Phe Leu Ala Met Ala Gly Phe 245 250 255 Thr Pro Gln Ala Ile Gln Ala Ala Leu Pro Gly Val Leu Asn Met Ala 260 265 270 Leu Ala Gly Gly Val Glu Leu Gly Glu Thr Ala Asp Ile Gly Ser Asn 275 280 285 Ile Leu Thr Gln Phe Asn Leu Thr Ala Asp Gln Met Asp Arg Val Gly 290 295 300 Asp Thr Leu Thr Ala Ala Phe Thr Arg Thr Asn Thr Asp Leu Arg Ala 305 310 315 320 Leu Gly Glu Thr Met Lys Tyr Thr Gly Pro Val Ala Ala Lys Leu Gly 325 330 335 Ile Ser Leu Glu Glu Ala Ala Ala Met Ala Gly Met Leu Ala Asn Asn 340 345 350 Gly Leu Arg Gly Ser Asp Ala Gly Thr Ala Met Arg Ala Ser Leu Ser 355 360 365 Arg Leu Ala Ser Pro Pro Lys Ala Ala Ala Asp Ala Leu Lys Glu Leu 370 375 380 Gly Val Ser Val Ala Asp Ala Arg Gly Lys Met Arg Pro Met Glu Asp 385 390 395 400 Val Leu Leu Asp Leu Tyr Lys Ala Thr Gln Lys Tyr Gly Gln Val Asp 405 410 415 Gln Val Ser Phe Phe Lys Asp Ile Ala Gly Glu Glu Ala Phe Val Gly 420 425 430 Leu Gln Thr Leu Val Ala Ala Ala Gly Ser Gly Glu Leu Gln Lys Leu 435 440 445 Thr Arg Glu Leu Gln Gly Ala Arg Gly Glu Ala Asp Arg Val Ala Lys 450 455 460 Val Met Ala Asp Asn Leu Asp Gly Asp Leu Lys Asn Leu Asp Ser Ala 465 470 475 480 Trp Glu Gly Leu Arg Ile Arg Ile Ser Asp Leu Val Asp Gly Pro Leu 485 490 495 Arg Ser Val Thr Gln Trp Leu Thr Arg Val Leu Glu Lys Ile Thr Ser 500 505 510 Leu Ala Gln Ala His Pro Val Leu Thr Arg Gln Leu Leu Ile Ala Gly 515 520 525 Gly Ala Leu Leu Ala Met Thr Ala Thr Ile Gly Ser Leu Ser Leu Val 530 535 540 Ile Gly Val Leu Tyr Gly Lys Leu Ala Thr Leu Arg Leu Gly Phe Asp 545 550 555 560 Ile Leu Thr Arg Ser Met Asn Val Val Arg Val Leu Pro Ala Leu Trp 565 570 575 Gly Met Val Thr Gly Ser Val Ser Leu Leu Gly Gly Val Ile Gly Ala 580 585 590 Leu Phe Ser Pro Val Gly Leu Ile Val Ala Ala Leu Ala Gly Ala Ala 595 600 605 Val Leu Ile Trp Lys Tyr Trp Asp Pro Ile Arg Ala Phe Phe Ala Gly 610 615 620 Val Phe Ser Gly Ile Met Glu Arg Leu Thr Pro Leu Arg Asp Thr Phe 625 630 635 640 Glu Arg Phe Gly Pro Val Phe Asp Val Ile Gly Ser Gly Ser Ala Arg 645 650 655 Cys Leu Thr Gly Leu Asn Arg Cys Cys His Arg Trp Ser Pro Ala Arg 660 665 670 Lys Arg Trp Ile Asn Val Pro Val Leu Ala Arg Tyr Ser Val Thr Phe 675 680 685 Leu Val Val Arg Tyr Ser Leu Phe * 690 695 <210> 1183 <211> 79 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16365..16601) <400> 1183 Met Cys Gly Cys Arg Lys Phe Phe Glu Arg Cys Gly Leu Trp Arg Glu 1 5 10 15 Glu Arg Thr Gly Asp Gly Ser Leu Ile Thr Val Val Cys Phe Glu His 20 25 30 Ile Glu Asp Phe Val Ala Asp Ile Ala Val Ile Phe Asn Trp Ser Pro 35 40 45 Ala Glu Ile Phe Met Met Thr Pro Gly Glu Val Val Ser Trp Arg Glu 50 55 60 Arg Ala Ala Leu Arg Ser Gly Asn Ala Asp Asn Glu Asp Ser * 65 70 75 <210> 1184 <211> 122 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16529..16894) <400> 1184 Met Lys Glu Thr Lys Asn Ile Asp Thr Glu Asn Thr Val Val Thr Asp 1 5 10 15 Thr Val Lys Glu Thr Ser Glu Arg Gly Val Lys Leu Thr Gln Pro Ile 20 25 30 Glu Arg Gly Gly Glu Lys Ile Thr Tyr Val Glu Ile Thr Gly Ala Ile 35 40 45 Glu Gln Ala Gly Ser Leu Arg Asp Leu Ser Leu Ser Asp Val Leu Asn 50 55 60 Leu Lys Ala Glu Ser Met Phe Thr Leu Leu Ser Arg Val Thr Ser Pro 65 70 75 80 Arg Leu Asp Glu Val Thr Ile Lys Lys Met Ala Ser Arg Asp Phe Ile 85 90 95 Gln Leu Cys Val Val Ala Val Asn Phe Leu Ser Gly Ala Asp Ser Gly 100 105 110 Gly Lys Asn Glu Gln Ala Thr Glu Ala * 115 120 <210> 1185 <211> 171 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16949..17461) <400> 1185 Met Ala Val Pro Lys His Leu Arg Phe Phe Thr Leu Phe Val Asp Gly 1 5 10 15 Glu Asn Glu Val Gly Lys Val Thr Ser Val Thr Leu Pro Lys Leu Thr 20 25 30 Arg Lys Thr Asp Ser Tyr Arg Gly Gly Gly Met Met Gly Ala Val Ser 35 40 45 Ile Asp Leu Gly Leu Asp Asp Ser Ala Leu Asp Ala Ser Phe Val Met 50 55 60 Gly Gly Ala Val Arg Glu Leu Phe Leu Lys Tyr Gly Gly Thr Ile Asp 65 70 75 80 Gly Thr Leu Leu Arg Phe Ala Gly Glu Tyr Tyr Thr Asp Asp Glu Ser 85 90 95 Asp Leu Tyr Glu Val Glu Met Arg Gly Arg Val Thr Glu Ile Asp Met 100 105 110 Gly Glu Ala Lys Gln Gly Glu Ala Thr Ser His Thr Tyr Ala Ile Lys 115 120 125 Asn Thr Tyr Tyr Lys Leu Ser Val Asn Asp Arg Pro Leu Trp Glu Ile 130 135 140 Asp Leu Leu Asn Phe Ile Tyr Arg Lys Asp Gly Lys Asp Ile Val Pro 145 150 155 160 Asp Arg Ile Arg Ser Ala Leu Gly Leu Gly * 165 170 <210> 1186 <211> 395 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(17461..18645) <400> 1186 Met Ser Glu Thr Arg Phe His Gly Ala Arg Val Thr Glu Ser Thr Asp 1 5 10 15 Leu Val Thr Ala Ile Asn Asp Val Asp Ser Ser Val Ile Gly Ile Val 20 25 30 Ala Thr Ala Asp Asp Ala Asp Ala Glu Leu Phe Pro Leu Asn Lys Pro 35 40 45 Thr Leu Leu Thr Arg Val Asn Asp Val Leu Gly Lys Cys Gly Thr Thr 50 55 60 Gly Thr Leu Tyr Arg Ala Leu Lys Ala Ile Ala Asp Gln Val Ser Thr 65 70 75 80 Lys Val Ile Val Val Arg Val Ala Glu His Lys Glu Glu Gly Gly Lys 85 90 95 Thr Gln Asp Gln Leu Val Ile Gly Gly Ser Glu Ser Asp Gly Ser Tyr 100 105 110 Thr Gly Met Tyr Ala Leu Leu Val Ala Glu Gln Asp Glu Ser Ile Gly 115 120 125 Tyr Arg Pro Arg Ile Leu Ala Ala Pro Glu Leu Asp Thr Glu Ala Val 130 135 140 Thr Lys Ser Leu Cys Val Ile Ala Gly Lys Leu Arg Ala Phe Val Tyr 145 150 155 160 Ala Thr Cys His Gly Cys Asn Thr Met Ala Glu Ala Ile Thr Tyr Arg 165 170 175 Gln Lys Phe Asn Glu Arg Glu Val Met Leu Leu Trp Pro Asp Phe Ile 180 185 190 Ala Tyr Asn Leu Lys Ser Gly Lys Asn Glu Thr Phe Pro Ala Pro Ala 195 200 205 Tyr Ala Cys Gly Leu Arg Ala Tyr Ile Asp His Glu Gln Gly Trp His 210 215 220 Lys Ser Leu Ser Asn Val Pro Val Lys Asn Val Leu Gly Met Ser Arg 225 230 235 240 His Val Phe Trp Ser Leu Gln Ala Glu Asp Ser Asp Ala Asn Ser Leu 245 250 255 Asn Asn Lys Glu Ile Thr Thr Ile Ile Arg Arg Asn Gly Phe Arg Phe 260 265 270 Trp Gly Asn Arg Thr Pro Glu Thr Asn Ala Tyr Ile Phe Glu Val Tyr 275 280 285 Thr Arg Thr Ala Gln Val Leu Ala Asp Ser Ile Ala Glu Ala Gln Phe 290 295 300 Glu Thr Ile Asp Ser Pro Leu Thr Pro Ala Asn Val Lys Asp Val Ile 305 310 315 320 Ser Ala Ile Arg Ala Lys Leu Asp Ser Leu Val Thr Ala Gly Lys Leu 325 330 335 Ile Gly Ala Glu Cys Trp Tyr Asp Ile Glu Asp Asn Ser Thr Thr Asn 340 345 350 Leu Arg Gln Gly Arg Val Arg Ile Arg Tyr Lys Tyr Thr Pro Val Pro 355 360 365 Pro Leu Glu Asp Met Glu Leu Tyr Gln Ser Phe Thr Asp Glu Phe Phe 370 375 380 Gly Pro Ala Phe Ala Val Leu Gly Gly Ala * 385 390 <210> 1187 <211> 108 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(18803..19126) <400> 1187 Met Thr Asp Thr Thr Met Gln Leu Leu Ser Gln Gly Thr Asp His Val 1 5 10 15 Lys Val Pro Asp Phe Asp Ile Leu Ala Glu Gly Lys Thr Leu Ser Gly 20 25 30 Val Ala Glu Arg Leu Met Ser Leu Ser Leu Thr Asp Asn Arg Gly Phe 35 40 45 Glu Ala Asp Gln Leu Thr Ile Thr Leu Asp Asp Ala Asp Gly Gln Leu 50 55 60 Gln Leu Pro Pro Arg Gly Ala Arg Leu Thr Val Leu Ile Gly Trp Lys 65 70 75 80 Gly Glu Pro Leu Thr Glu Lys Gly Thr Cys Arg Phe Asn Leu Ser Met 85 90 95 Gln His Pro Phe Gln Leu Ser Leu Ser Val Phe * 100 105 <210> 1188 <211> 344 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(19077..20108) <400> 1188 Met Leu Arg Asp Thr Gly Gly Ile Lys Pro His Glu Arg Lys Arg Ala 1 5 10 15 Val Ala His Leu Thr Leu Ser Glu Arg Glu Glu Ile Arg Ala Gly Leu 20 25 30 Ser Ala Lys Met Ser Ile Arg Ala Ile Ala Thr Ala Leu Asn Arg Ser 35 40 45 Pro Ser Thr Ile Ser Arg Glu Val Gln Arg Asn Arg Gly Arg Arg Tyr 50 55 60 Tyr Lys Ala Val Asp Ala Asn Asn Arg Ala Asn Arg Met Ala Lys Arg 65 70 75 80 Pro Lys Pro Cys Leu Leu Asp Gln Asn Leu Pro Leu Arg Lys Leu Val 85 90 95 Leu Glu Lys Leu Glu Met Lys Trp Ser Pro Glu Gln Ile Ser Gly Trp 100 105 110 Leu Arg Arg Thr Lys Pro Arg Gln Lys Thr Leu Arg Ile Ser Pro Glu 115 120 125 Thr Ile Tyr Lys Thr Leu Tyr Phe Arg Ser Arg Glu Ala Leu His His 130 135 140 Leu Asn Ile Gln His Leu Arg Arg Ser His Ser Leu Arg His Gly Arg 145 150 155 160 Arg His Thr Arg Lys Gly Glu Arg Gly Thr Ile Asn Ile Val Asn Gly 165 170 175 Thr Pro Ile His Glu Arg Ser Arg Asn Ile Asp Asn Arg Arg Ser Leu 180 185 190 Gly His Trp Glu Gly Asp Leu Val Ser Gly Thr Lys Asn Ser His Ile 195 200 205 Ala Thr Leu Val Asp Arg Lys Ser Arg Tyr Thr Ile Ile Leu Arg Leu 210 215 220 Arg Gly Lys Asp Ser Val Ser Val Asn Gln Ala Leu Thr Asp Lys Phe 225 230 235 240 Leu Ser Leu Pro Ser Glu Leu Arg Lys Ser Leu Thr Trp Asp Arg Gly 245 250 255 Met Glu Leu Ala Arg His Leu Glu Phe Thr Val Ser Thr Gly Val Lys 260 265 270 Val Tyr Phe Cys Asp Pro Gln Ser Pro Trp Gln Arg Gly Thr Asn Glu 275 280 285 Asn Thr Asn Gly Leu Ile Arg Gln Tyr Phe Pro Lys Lys Thr Cys Leu 290 295 300 Ala Gln Tyr Thr Gln His Glu Asp Leu Val Ala Ala Gln Leu Asn Asn 305 310 315 320 Arg Pro Arg Lys Thr Leu Lys Phe Lys Thr Pro Lys Glu Ile Ile Glu 325 330 335 Arg Gly Val Ala Leu Thr Asp * 340 <210> 1189 <211> 65 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20152..20346) <400> 1189 Val Arg Ala Leu Cys Ala Val Asn Gly Ser His Pro Glu Asn Leu Arg 1 5 10 15 Phe Trp Leu Lys Ala Cys Pro Val Val Leu Arg Glu Arg Phe His Gln 20 25 30 Gln Cys Lys Cys Arg Phe Asn Trp Ser Thr Gln Gln Leu Cys Glu Asn 35 40 45 Met Gly Leu Arg Arg Phe Gly Thr Met Glu Glu Arg Asn Arg Leu Gln 50 55 60 * <210> 1190 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(20367..20648) <400> 1190 Met Arg Cys Gly Leu Leu Met Ala Ile Cys Leu Cys Leu Val Ser Phe 1 5 10 15 Ser Gly Tyr Ala Ala Thr Gly Lys Ser Asp Ala Gln Ile Lys Lys Glu 20 25 30 Ile Ile Lys Glu Ser Ile Glu Ser Tyr Pro Gly Asn Cys Ala Cys Pro 35 40 45 Tyr Asn His Ala Arg Asn Gly Ser Arg Cys Gly Gly Arg Ser Ala Tyr 50 55 60 Ser Arg Asn Gly Gly Tyr Asp Val Val Cys Tyr Glu Gly Asp Val Thr 65 70 75 80 Asp Glu Met Ile Arg Gln Trp Lys Gln Glu Asn Ala Glu * 85 90 <210> 1191 <211> 16943 <212> DNA <213> Escherichia coli O157:H7 <400> 1191 gtagtaaata agtgaactat tcagattaaa atgttcaact gaaagattat actgcaggag 60 aatcatttca ttggtaatag atctcagcac cggattgtta ataggtgtat tattcaagct 120 tactcgttga ggatgaatat aactaattgg agcatatata atctttctta gggcaagatt 180 cataacgttc tcatatgtct acttaatttt caacctgact aaattagtta gaatggccct 240 atacttccat aacagccagc aagtcgctac ggatattaat gcaagtaaga tagaaaccgg 300 catagcctta tcataagcaa aaacaggttc gctaatttca tatgttggtg cttgctcaat 360 aatgtctctt cgttttgaca atacaacaga aatattctca tattgtacgc ttgcaaaact 420 attaacaata aatctcttta tgtcatttat ttttatttct ggattgatat ctttttcata 480 tactgcaagt acagaaatat gaattggtaa agcagtttta ccactatcgc cagtatcaac 540 atcgtaacta acatgtactc tcgaagaaac aataccatcc ataattttga gagattgctc 600 taaccgctgc tcaatagcag aatatagcct tgctttttcc gctcgtggag atgaaacgag 660 tgcatctgca gggaacatct gcgatatttg aatatcaggc ttacccggga gattgtagat 720 ttttagccaa tccaccgcag aagcaaaatc cgttggttca acatagattg agaatccagt 780 tttgccttga tccttctttt cagcattaat attatgtctt tgtaaaacag caaggacatc 840 attagcttgc tgttgatcaa gatggttcag taattcctgc tgcttgcagc cgcacaacag 900 caggataaac aataataatg atatatattt catgagcggg tcaacgtctc aactgcagcg 960 acaatttttc ttgctaatgt tcccaccaat gaaacctcga cattataatt aagcacatga 1020 tcctgcaaga ctaataattt ttcaggagtt aatccttttt tatcagacgt taatgcttgt 1080 aacgcatttt gctgccaatt ttcagtttgt acagcatagt tagcaaaagc ggagatcatt 1140 ttatcatccg ggttgtcaag attgagaacc cggtcattta aatcaatcac tttcgcttgc 1200 tgtatttcat gagcagttga ttgctcagct ctatcaatag gtggcatatt gcttactgac 1260 ataataaaat ccttatccag tttagcggaa gttttgtatg attgccgaat caagatcttt 1320 atacgctttt acaacgttag attgcgcatt tcgatataat gtatactcag ctaatgcact 1380 ttgatattcg gcaaggaatt tcgggtcgga aggattggtt gctaaatcct ccaacgcttt 1440 ttcaacttgc tggttcagat catcaacgcc ctgatcaaat tgtttgctga tgtccataat 1500 ataaccattc caatctgcca taagtcctcc tcaattattc ctgaaatgtc cacttgctac 1560 cttgagactt ctcgaatcgg ttatctccgt agctaaatga actattattt gtgtcctgat 1620 ttttcaaatt cacattaaat cttacatatt gtttacccca ttgtttataa tattcgtcaa 1680 catagttatt tattttgttt aattcactgt cgcttaacgt accaatgata ttgaaataca 1740 cattgttagc tgttttatat ttttcataag aaagacctat tgcagacaat gtttcaatag 1800 cctgactttc caatacatta tcatctaata ccgcaatact tatattgctg gcatatggca 1860 tagtttgtag taacccttta ataagattgt cgattagttg ctgtgtgata gcattccgtt 1920 gcttactcac ggtcagtctg ggattactgg catctaatag ctgaagttta aaatattgta 1980 aatcagggaa attatcagca agccatgaaa aaattcgtat cgattcatca tcaggattta 2040 tcacccgtac tggctttcct ggttgatttt tttccagtgc ttgtttgacc cagactgctt 2100 catccaaact attggtattg atatagatga catgatctct accatataaa atttcataat 2160 tcctgttttt gtttacaaga atcttatcga tatgtctcag ctgcggatca ttactggcat 2220 taacaatata aaaagcaatg aaaatgataa caaaaagaaa aaaaagcatt acatacttta 2280 acagtttact gctaaagaaa tgttgttttg tagaaataat gctattttca ataatgcctg 2340 gcaatgaata ctgccaaact tcattttttc ttttacagca aatttgagac ctaaaacttc 2400 tatttgctga ttcaatgtta acgttctatc ttcaggttct tgtgctgtta attctctgat 2460 tgttacaacc agatcagggt cggtagtgat tataatctca aaactacctg taagctcgcc 2520 ataaggaacg actattgtat tttctggtaa ctcagaaaaa gcatcacttc ttcctaacga 2580 aacatcatta ccaatgataa caagtagacg cccattaagt atttcatact cgcatccatt 2640 ctatggtccg ctcaacaaac gaatggcata agattccaat aagtcttgtg ataagaattt 2700 atcattattt tccatgaata ccacccgcta attccataag ctctagttta gagtagtgta 2760 acaagacgga aatttcatga ccaaattatg atgagacaga ataaaaaaat tataattttg 2820 aggaccattt taaatgcctc tatgcataac tttatttaca atttaaggta taaaccctat 2880 tccctcaacg ttaagcaaat ataacaatta ctcttatttt aaattttaca cataatattt 2940 accctaaatg attttagagt acaggttggc atatgcaagt cttttccagt gatgtctact 3000 tcactgtagg cactaatgca ttattagcat cccaaaagga atattacagc gatttagttg 3060 cgttggttga tcttggacat tcgttcgttg ttattgatga gcatcaacat cgaaatctca 3120 aaccaaatac agaacctgta aacatccttt tgagtaacaa tttcatctgg atcaataaga 3180 atattacatt atctgattta acgcatttcc tggtttcaaa tcttcataca caaaatgtgt 3240 attccacaca agaaccactt acccatgatg agatagatat cctgcggtta tgtgtttcat 3300 attcattaaa gcaaattgcc attattaaag gaattgatta taaaacagta tcatatcaca 3360 aaataagagc cctcaatcaa cttaacataa aaggtactgt tgagttgttt atagcactct 3420 gtgaatggga taaacattat tttaaactcc aatcttgcgt aagagaaagt tgatatgtca 3480 ttagtaatga tataatagta aaatcataat aaccatcgcg ctgatatcgt tgctctctgc 3540 atgcaccaga gaaaattcat taaaggagaa tcaaaataaa agaagtggcg aatcccaagc 3600 gatagtagat gcaagacagt tctttagcga acacccggaa tatatatcat cagcagaact 3660 ggaggaaaag ctatatcgcg aatttgcaca ggttactaca gttccagctt ataaagagat 3720 gagtatgtat caattgcttg tcatttcgca agatcgttta actcattaaa taaaaatcta 3780 cacgtttttt gcgtgtagat tcttataaat ttttgactac gatacatgtt taatttttta 3840 aattattgtc attattctcg ctttttgtgt cttcaccctc aatatattta tcttctgaag 3900 agagctgttc atctggaaca ggttgtccag cattctccac atcttcaagc cacagcagaa 3960 gacgtaatat ttcatctata ttttcgaagc taacataatc gtagcgacga tgggtagcat 4020 aaatttttcg tgctaatttt ttatctgtaa taattggtat cccgatttcc tttgcatatt 4080 tccttacagc taatgctacc tcattagttt ctcttacaga aatcaatgga ataggtgaca 4140 gatgtggctt aaagtatatc cctattgcaa tgtgagtagg gttggcaatc atcaaacggc 4200 tattactgac atcagatttc aattgctcag aaagaatttc ctgatggcgc tctctgcgtt 4260 tagacttaat ttcaggattt ccttcttgtt ccttgtattc tcttttaact tcttgtttat 4320 ccattttcat atctttcata aataaaaaat attcagcgat aaaatcaaaa attaagacaa 4380 ttatcatact gccgagacaa tacagtatga gaaggaatag catctctccc caatctgata 4440 ataaagatat gatatctcca tcaagagttt taaaaagcag tgatttatga ttactccaaa 4500 atactttgat ctccaatgca aaaaaaataa tataaagaat tgctttaaca aattctttta 4560 cggtttttaa gccaaatata cgctttaaac catttactgg attcaatgaa tcaaacttta 4620 attttacagc ttcagttgct aattgcattt tactttgaaa ccaggagaca agtattgttg 4680 tgaacatgca aaccagcaaa aaaggaatga tcgttttcaa ccaaccaatc cccatagctt 4740 taaaatagtc ccaaatatcc ggtttagcgt tatgatcaag gatatattca agaatcgaca 4800 taatgtgatg cacatcaaaa acatatccga gatataaagt acccacaagc attattacag 4860 aaacggttaa gtctctactt tttagaattt gccctttttt agaagcatcc tgcagtttct 4920 tttgtgttgg cttttcagtt ttatttgcca tgaaacactc tatttctcaa tgtatagttg 4980 caattgttct gggaaaaagg ataacggcat cactcgttca gccagtattg ggccaaaata 5040 aataattaat attaaaaatg ccagcgcact tttgacagtc agtgaaatgg caaaagcatt 5100 tagttgtgaa gcatagcgtg ccagcaatcc caggacagcc tcaccaccca gcataacggc 5160 aattacgggg cttgcgtaaa cgatagtatg agtcattata ttattaatat atgaaaataa 5220 aggctctaat ttaggaaaat taaaacttcc tgaaggccat aaattataac tttgctaaag 5280 agtttccaga ataaagttca atccaccgtt agtaagataa accgctgcag agaaaaggtt 5340 aaataatctt gctaattccg aggtatcgac acctgtagcc ggatccaaag tactacttaa 5400 cgttgcaccg cgttggttat cgataaagct acctatagca aggaaaatcc aaaatggaga 5460 tgctaataag caagcaatga acagccctat gataatttct cttgcagcta acaaagcgat 5520 atcgatttca tttaaggtcg ataattcata gtggtaatgc tgaactaatg cacatgatac 5580 cactattatt attggatgac ggactactgt tggtatattc ccactggcga aaaatggtaa 5640 caaatagaaa gttggtgcca atcggcaaaa accgagcgct gtagcagcca gtagactatg 5700 caactgatag agtatcacct cccccatgct atcctctcgc aaatgctaaa ttcagcattt 5760 caataccaaa agaatataat ttttcaccat accatccgct cattaaaaaa aagcaaatac 5820 ttacgcacaa taatttcacg ccaaatggca acgtctgttc ttgcaactgc gttaccgttt 5880 gaaaaagccc taccaataaa ccaacaaatg tcgctactgc aataggtcct gcagacataa 5940 ctaaaatcag atacagcgcc ctattccctg caaaaacaat gtcatccata tttttttcct 6000 cagggattaa tggataggtc aaaatattgt aatatgagtc cttttgataa cattgtccaa 6060 ccgtccatcg cgacaaacag aattaatttt atcggtgtag atatggttac cggactcatc 6120 atcatcatac ctaacgttaa cagaacgctg gatataacca gatccactac aacaaagggt 6180 aaatagatat aaaaacctat aataaatgca ctttttatct cacttaacgc atatgccggg 6240 agtaacgaga aaattgaaat attatcatca tcgattatct cttcattgtc ttcagaacta 6300 ttcaccttct gaatcttttc aaaaaagcta accaactccg gttcagaata ttttatcaaa 6360 tatgatttat aaccactcat gcctgtctca acaaaattaa caaccgacgc tacattattg 6420 aatgaaagat tctcattctg actgttataa tatatttcct tcccaaccgg catcattaca 6480 aacattgaca atagcaaagc aaccccatta agtgtcatat ttgatggcac ttgctgaagt 6540 cccaatgcgt ttcggacaat aacaaaaaca atcgagaatt taataaaaca tgtcccggat 6600 gctattataa acggcaatag tgtaaataat gatagtatcg ctatcagcga aatgctattt 6660 gacattatta tgccctgata accaagaatg aatctctacg cccaatttat catccacttc 6720 aacaagttcg ccatagccag ttagcgcgcc atttacacgt atctctatat ttttctcaga 6780 ttcaggaagc agagatatta ttctttttgc acagagctcg tctatttcat atagattcat 6840 tattttctta ccaagaacaa actcaatttt tacaggcaac tcttcaaaac tattaatcat 6900 ctgttcgtca ttttcatcat aaatctcact ctcgcttttt ttgatatcaa agtcatctgt 6960 ttcaaaatct tcctcgtact gaaaatgatc agccattttt aactcctctg gataaattaa 7020 atcacaaatc tttgtattat aaataaccgc ataagccata ttatttgaga ttaataaaac 7080 atcaccgact tcaatatcaa caatagttct ataacatgtt ttactaaatc caattacaaa 7140 atgaatgggc caatataatg attttttgtc taaagttgga gcgttttcgt attggcagac 7200 tgtgacttta tctaaccaaa gattcaattc ccctgtccat attcttatca gtggttgagc 7260 tggactcaat actccatcaa atactttacc tacgcacaaa cgattatatt ttagttcagg 7320 atactttaga tttaacgggg aactggataa actgagccat tcccctatta acctttccgt 7380 ttctggcatt aaagccatcc cagcgagctc ggcagaaatt aagggaaata tttctcgaag 7440 caacacccat ccagaccagc tgccactctc ttctgctatc ggtagccatt tagcactaaa 7500 ttcgggcatt aataatgcaa catcttcgcc attttctttc caattttgaa aagtggtttc 7560 aaacgtagag tgtttcgatt tactttcctc agaccgaaca ttaactttca tccttctgat 7620 cgttttcgaa tttgccttca ttttcttgct cctcatgagg ctgatgtcgt tgtccttgtc 7680 gttcatcttg ctcagtcaat acccaacgtt gtgctgtaac atcattgtgt tgggcttcat 7740 ggagtctgtc ggagacaagt gtgtctgatg gttttagtcg tatcccttca ctactttcca 7800 gaatccggac cgtatgattt tgtccccaac gctgaaactg atatgtcaat tcattttcgc 7860 gcacattggc attattagca gaattattta tatcattctg attgagcgta ttaacattcc 7920 tttgcttttc gatatgttga gtaaacatgg ttctgttatc agcaaacctt ctttcgttag 7980 taatgtctaa tgaatgggcc tgcggtccat ttattttgtc tccatcgcgg tatttttttt 8040 cacgatcttt attattactg tgtttttgat ctgtgatgta ttctgtatgg ataccattat 8100 ggattttttc cttaaattgt atcgttcgat tagatagttc agaattaata ccctgatctc 8160 gtgaagtcat attgagaagt ttctttgtag aaaattgctc ggctcctttt gtttgcaaag 8220 aaagagatgg attcctgtca acctagagag acgatttgtt gtcaatagac ttcatgtgcc 8280 cattcttttt ccccaacgta gaaaattggt tatcctgagt ctgacgtaat aactggagaa 8340 tggttccagc gacaatctca ctcatttctt tatttttttt gtttttcttt aagaaactgt 8400 ctaaatccga agcagaatta tcgggtgtgt ctgtgtttaa aattttacaa tgttcaattt 8460 tcttgacttc gtccattata tttttcctcc tgttcaagct cgtcttgata aagcatctga 8520 tttaaaagtt gttttttgat gcgctttttt agtcggtcgt atttttctcc ttttagccac 8580 cagtgttttc tttgtgcttg ctgttgaact atttccttgt taagtatttt tcgccgctcg 8640 gctatttttt gcttttcaag atttatctca gcgatctgct gctgaatgac tgtaacttta 8700 cgtaacgagt aaaatatatc ctggcgaaat acaacttcgc cgagtaactc cttcatatct 8760 aacagtgact gcaggttttt aagttgcata tcatacaggc gttccttttc ggctaacttt 8820 tctttttctg catttaactt ttgtaatgat gcttcacatg cagccaggct ctgcgctgtt 8880 cttctgataa gtcgattaac tttacttaac aattcgttca agctctttta gcgtttcact 8940 cattggcatt ttttcattaa ctgactgttt caaccaattt gtgagtttag gccgggcatt 9000 catagcaaaa tcattttcag cattttgccc tgcgcgatat tcccctaagt caataaacac 9060 ctgtagatct tccaaagttg tgaggttctt ccttacccgt gcagcattat ctctgtgttt 9120 ttcatcagtg acctgaccaa atactcgact cacacttttt agaacatcta ttgccggata 9180 gtgaccttga cccgcgagtt tgcgacttag atagatatgg ccatcaagga ttgagcgaat 9240 ttcgtcaccc agtgggtctg attcatcttc cccttccagt aacacggtat aaaactcggt 9300 aatacttcct tttagtgttg gtcccggcct ctccagtaag cgaggcaaac tgtcaaaaac 9360 agaagcagga taaccacgtc tggcaggtgg ttcacccgct gccagtttca tatcacgtag 9420 tgctcgtgca taccgcgtca ttgagtcgat aaaaagtaca actctctttc ctcgatctcg 9480 aaaatactct gccacggttg tcgccatcag ggcggcatta caccggtcta ctgacgaaaa 9540 atcagaggtg gcatagacca atacgcattt cgctgcattt actgattttt tgagcgattc 9600 cgcgcattcc gtaacttccc taccacgttc gccaatcaag ccaataacaa acacatcagc 9660 ttcagtattg tttacgagca tatgcattaa aaccgttttg ccacagccag ccgaggcgaa 9720 aatcccaaca cgttgaccaa tgccacatgt cagtacgcca tcaatgactc ttatccgtgt 9780 ctcaagtggt gtattaataa ctcgacgttc ctgatacgac ggtggcagtt catcaatcag 9840 gcgtaaattt cccctatcgc ctggagtgtc cgggacaaac ctttccataa tttgaccaga 9900 ggcattcaaa accgaaccaa gaaaggcatc actgatctgt atggttaact gctctcccgt 9960 tggtttcaaa actgcagtac gtgtaagccc cacagagctg cctataaggt ttaataatgt 1002 0 cttcccattg cgaaagccaa cgacctgagc cctggctata cgttcatttg cttgcctgct 1008 0 cgcataaatt tcgcatactt cacccacaga aacgtcgtca agttctgctt caatcagaga 1014 0 gccgtttatg ctatgtaagt agctgtattt atttaataat tttaattttt tcataccagc 1020 0 atgctccata tcgcaagaca ttatcctaaa tagttttcag aatattaacg ggaacatttt 1026 0 ccgttagttc cccgtacgaa agtacttcga ggtctcgata actagattca ataagttttt 1032 0 tgataaaacg acgaatatcc acagatccca gtaaaataat gtctttaata ggaatattga 1038 0 ttccagaaag tgccagttta aaattatcca gaatcatctc agcttcggat gcatcgagat 1044 0 taagaaaagt accgccagcg gtaggcctga caccatctct gattctgtcc tctatttcag 1050 0 gcgaaatcac aattgcttta atttctccag aatatgaaaa cttatggcaa atgtagcgac 1056 0 ctaatgcacc tcgtacatgc tcgacgagtg tgattatatc tttctctcgt gggctccata 1062 0 atgctaaggc ctccataact aaccgcatat tgcgcactga aattcgctcc tggatcagac 1068 0 gctgaattac ctctgaaatg cgctgcacgg ttatatatct taatatttct tttaatagat 1074 0 cagaatactt catctctaat tgatcaagaa tatattttgt ttcttgtata ccaaagtact 1080 0 cattaatatt atgagccaga cagacagata aatgattata catttcatcc atggccgtgc 1086 0 gagtataaca gccaattttt gttaattttt gagcatcact tttcgtaacc caataatatt 1092 0 gttcaccatt actatttaca atgacaggtt tcttgatcaa agtcgaaacc acttcatctg 1098 0 aatattcaac caacaagaca agatcatgat aaattttaaa ttgtgaagct ctgacttcat 1104 0 ttagcattaa tatgacatct tcatcattaa gaccttcccc ctcacgaatg acaataccgg 1110 0 gaatgcggat accatactca ataaaaaact gactacgaat cctatcagca agattgattt 1116 0 cagtgtattt tttagcctgt acactattca taatcaagac caagggtacc gtttcggtaa 1122 0 taacctgatc aagtttatta atgataccta atgagatatc atcatcttga ttatagggtt 1128 0 ccaacccaac ggtaatatct ccctcaacaa ccgtttcttc agtccctttc tttttgaatt 1134 0 taaagtaaaa gtaaattcct aagattactg ccaaacataa aaacactaga aggggaaaac 1140 0 ctggaagcaa cccaatactt agcgcgagga cacatgtcac aacaatgaca aaagaattac 1146 0 ttaataactg ggacattata ttttgcccca tattatcact atcgccattt acgcgcgtaa 1152 0 cgataaatcc tgcgctaata gcaattaata aagctggaat ttgagaaaca agaccatcac 1158 0 cgacagtaag aattgtgtag acagtcaacg ctgttgagaa atccattcca ttttggccta 1164 0 ctcctactga tagcccaccg ataatattaa caaagataat aataatgttt gcaatagcat 1170 0 cacctttgat aaatttcatc gcaccatcaa aggaaccata caactggctc tctcgttcta 1176 0 atacactacg acgttctttt gctaaatctg catcaatgat cccggcgcgt agatcggcgt 1182 0 caatgctcat ttgtttacct ggcataccgt caagcgaaaa gcgggcagca acttcagcca 1188 0 cacgttccga acctttagta atcacgataa actgaacaat agtaacaatg gagaaaataa 1194 0 caaaaccaac taccaggcta tctccaataa cgaactcacc aaaactcgtt ataatttctc 1200 0 cagcatccgc ctcaagaagt ataagtcgac tggtactgat cgccagcgcc aaacgaaata 1206 0 acgttgtgat aaggaggatt gatggaaatg aagaaaagct taagatccta tcaacataga 1212 0 atgatcctaa aaatacaagt attgccaatg ttaagttaag cccaatcaaa aagtcgatta 1218 0 aataggtggg caatggaatt atgagcatgg cgataatcat caccattaat ccaagaatta 1224 0 ttaattctgg atgactcctt aaccctacca aaactttgtt aaacattgaa catcaccttc 1230 0 ttccatggtt ttttattttg ttttttgtta cagttttgtg tatcaaagag ctctgctgca 1236 0 aatgttactt ttattgcctg tttacaacac tccctaatct ctaataattg ttcattatta 1242 0 ataaaaagtg aaaatggaag atttgtacat ccactgtaaa tcgccttcag gagtaacgtt 1248 0 ttgtctttat aattagcatc tgcgggaagg gtcaccagtg cattgttcag gagttcctct 1254 0 gcagtctcag gaaattttat taacgatatc agaaaaaata tccagtaatc ttctgcgctg 1260 0 ataaattttt taattattgg gttattcatt aaagttttca gaaataaagc ctctgccgac 1266 0 tgaagagaca atagttgtga caacttattg agaaacatac caaattccaa tgatgaacaa 1272 0 ctcgcatcaa gtgcatttat atctgagaaa agcgtctctt tgataaattt tgtcaccaac 1278 0 attctatttt gatagccata actaccaatc cattcgacat aagtatctac agcatcgtct 1284 0 tctgccatta aaaattgccg ataactcgcc cttagtaatt ttggatttaa tgacagcgcc 1290 0 tggccaaata actttgcttt taatgccgag ttaattccgc tattaatgaa ttttttagta 1296 0 gtctcttgat taacttttct aagtaatgct tcagcgttta gccggacatt ttctgatatt 1302 0 tgttttttac gtaaaattgc acgtaacaca actaccagat cgctttcatc tgggaataat 1308 0 tttttagcaa agctatacac ttcatagtca tgggtagttg cagccttaag cgcctccata 1314 0 actttgtcgg ttttttctat tggctggtct tccaggacat attcttctcc gtccagaaaa 1320 0 ttggccagtt gttcttcgta aatttttttc ttcataaact gcgttaacgc tgctgacatc 1326 0 tcgtcagtag cttgtaagaa ccgagcttct ttacctgcgg gatcatccct cattttaggc 1332 0 atttcagctt caatgtcttc attatcttct gtgataatgt cctctaagcg agaaacttcc 1338 0 ctggctcttt ctaatacacc gacatgctct acatgaatcg ccatttcact atcctccgac 1344 0 gacttcacga ttcaggtaag tttttatcca tttctgcagt aattcatcgt tgatttcttt 1350 0 attttttgcc atttgctgtg taatcgctct ggcatcaacc gcagcctcat tcgcattatt 1356 0 catcatgcgt tcatcgatct ctcttggctc aataagaaag acacgaacga tgttattcgc 1362 0 atttgttcct tcataaccaa ataatttacc aataaatgga atgctgccta atattgggat 1368 0 cttgcgactt tcataggtat tcgtatcgcg tgtatatccc ccaatcaaaa gacttttccc 1374 0 ttggggcacg cgtgcaatag tacttataag tgttctacca acctgaggca gatcatcaac 1380 0 attggtcttg tcggaattga tttcatttcc atcttcaata ttcaagagta attcaatttg 1386 0 atttcgcgca gcaaatcgtg gtagcacgct aatcatcgta ccataggtta cttcatccaa 1392 0 ttccgcagta cgctcgccga ctaatttagt atagaaagtg cggttattat caaatatagc 1398 0 aggaatattc tcttgtgtta aaacgacggg acgagcaaca acggcggctc ttcttttttg 1404 0 tgcaagtgcc tgtattgttg caataaactg tgtcccatca agggtactaa ttgaacctga 1410 0 attattaaat gatgcactta agctggatcc aatttttatc gtgcccgacc agtcagcacc 1416 0 tagctgttct agatcagtct tatcaatatc tattatccat aaagataatt caatgtgtcg 1422 0 ctttggaata tcaagcgtag ctactaactt ctcgataaaa tcaacctgag atactgttcc 1428 0 tttaacaagt aaactgttgg tatcaggata tgcaataatt tgtatatcgt cagtctctgg 1434 0 cgctcctgct gtcgatatta ttttctctac ttgtaggtca tcatcttctt cagccccagg 1440 0 aaaaggaggc atacgtgata cgttttttag ttgttgacga cttgaaattt cagaaagtac 1446 0 gttcacccct gtgctttgct taatgttatt atttaacaac gtcgatagta cttttgccat 1452 0 gccaggaata actatctttt cgccacgtaa ctcataagtc cggtcattaa cgaatgtgtt 1458 0 gaccagatga attattccta ctttatttcg accgatctca atgccatcgc tgttttgctc 1464 0 cattaatttc gcagcattaa cgaccaggtc aacataaacc ggtggccccg atacatagaa 1470 0 agtaccattg ccgtcccctt taatttcata acgagagtta tacagacccg atttttttaa 1476 0 gaaattatta aactcattcg tcgatacctt tctcagatta atcaatgcat tacgcatctc 1482 0 tgatgagtca tagatataaa tagctttgcc atcatcatac caaataagcc ccatctgtgc 1488 0 cgacaggcgt tcaatcaagg catagggttc tgttaaatca aaatttccgc tgatctgttt 1494 0 cttcatggca agcttactaa ctattgtagg cttacccgca tatgatgaaa ccgtttcaaa 1500 0 aaaactacgt agattttctt tatttgctac gtatccattc gctgctgcgg catatgcacc 1506 0 aggagtcaat aatccattaa aaatgcataa gactgaaatt aatataatag taatgcgtaa 1512 0 ttttattttc ataacttttt acatagttct ctcggtgttt ttcctaaccg gctttttact 1518 0 tcggctgaaa agtgtgatga ggacgagtaa ccatatttat gcgcaatagt tgtcatatca 1524 0 ctgtttcctt caatgatttc caacacggct ctggcaactc tccagccaca taattccgtt 1530 0 ttaactttac cacccaatgc ataactacat aaacggcgaa aatgtgaata cgatacgccg 1536 0 taaagctcac caagatcata gagtgaagta tgtatgagcg attgcgataa taaataacga 1542 0 accagtttat agcattctgt ttttcttaga tgctgaaaca ggatttcatt aatattatcg 1548 0 ctgctcagat aagtggctaa aaaccaggct tcacttgcaa ctttactgaa tagcacaact 1554 0 tctgatgcaa agggcaaggc atcagcaaac aattcatggt gttccctttc cacactcccc 1560 0 gttgattcat ctataaaagc taataattta ctcaggatat caatgcgaag tggatgataa 1566 0 attactttcc ctgcagttac ctcaatttgg cttcggtcaa tgagcagtaa tatatcttcc 1572 0 actaccatta atttttgatg gttattacca atcgtaataa caagggttac atccttgttt 1578 0 tcatttcccc gtaagaacca catttcaggg tccagtaggg ttaacttctg tccttgaagc 1584 0 aaaacattca ttggaagtaa cagcccttct tcaatcatgt ttcatctcct tattccatat 1590 0 tctcattctc cataaacttg ctataaaaac atgattaaaa agtgatgatt actatttata 1596 0 aaataatgat tttgttatga gcgaatagct atcagccact tacactagta cgtcatcctg 1602 0 tccatataca gatttgtaac tgttgatatg ttttacttaa acacacctcg tattacttat 1608 0 aacacttgtt tggtaactat tttcaataca aatcatattt gttagttctt cattaacaca 1614 0 ctgcgagtgt tttgttactc cccgcatata ttttattctc ttgttcgatt ctatttttct 1620 0 taatcgatca tataattttc ttgttagtcg gatttacgaa tcatgagact tataatggaa 1626 0 ggaatgagac taagcggcca ggttaaacct gtaattattg cagcaaacaa ccgatatgtt 1632 0 actttttctt ccgagaagat aaatattaaa gtcgatgtca caaccagacc tatcaggtaa 1638 0 gctaacagta atttattgat cacttttacc tcccctttcg atttctcttt gagcggtcct 1644 0 tttaatccag gaccgcctca ttatgaaaat tatttaattc cctcatcatt gataaggttg 1650 0 gacatctctt tcaacatgag agtcattgaa gctttcgacc aatttagcgg aatgataggg 1656 0 cttggcgctt catgcaaagt tcccgacttg tggatatagt tatagctttc gggaagtgcc 1662 0 atttctggta cgctcctgcc atttgcacca atcatattct cgcctgttat ttgggccaat 1668 0 gatctattca taaattgtac tgagtcattc aaatactctt cttttcttga ttctttataa 1674 0 acaattgctg ctgattttgc ataccatgag tcaaaaaacc attctgcttc tgttgatgga 1680 0 atgaagctct tttctctttt tgcatgcgaa ttttgatcgg tatcggtttt aatatcattg 1686 0 aaccaaaaat ttgccgactg ataattatcc ttctcgtatc tttttatacc atacggacct 1692 0 gctagttttt taactatttt tag 1694 3 <210> 1192 <211> 245 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(199..933) <400> 1192 Met Lys Tyr Ile Ser Leu Leu Leu Phe Ile Leu Leu Leu Cys Gly Cys 1 5 10 15 Lys Gln Gln Glu Leu Leu Asn His Leu Asp Gln Gln Gln Ala Asn Asp 20 25 30 Val Leu Ala Val Leu Gln Arg His Asn Ile Asn Ala Glu Lys Lys Asp 35 40 45 Gln Gly Lys Thr Gly Phe Ser Ile Tyr Val Glu Pro Thr Asp Phe Ala 50 55 60 Ser Ala Val Asp Trp Leu Lys Ile Tyr Asn Leu Pro Gly Lys Pro Asp 65 70 75 80 Ile Gln Ile Ser Gln Met Phe Pro Ala Asp Ala Leu Val Ser Ser Pro 85 90 95 Arg Ala Glu Lys Ala Arg Leu Tyr Ser Ala Ile Glu Gln Arg Leu Glu 100 105 110 Gln Ser Leu Lys Ile Met Asp Gly Ile Val Ser Ser Arg Val His Val 115 120 125 Ser Tyr Asp Val Asp Thr Gly Asp Ser Gly Lys Thr Ala Leu Pro Ile 130 135 140 His Ile Ser Val Leu Ala Val Tyr Glu Lys Asp Ile Asn Pro Glu Ile 145 150 155 160 Lys Ile Asn Asp Ile Lys Arg Phe Ile Val Asn Ser Phe Ala Ser Val 165 170 175 Gln Tyr Glu Asn Ile Ser Val Val Leu Ser Lys Arg Arg Asp Ile Ile 180 185 190 Glu Gln Ala Pro Thr Tyr Glu Ile Ser Glu Pro Val Phe Ala Tyr Asp 195 200 205 Lys Ala Met Pro Val Ser Ile Leu Leu Ala Leu Ile Ser Val Ala Thr 210 215 220 Cys Trp Leu Leu Trp Lys Tyr Arg Ala Ile Leu Thr Asn Leu Val Arg 225 230 235 240 Leu Lys Ile Lys * <210> 1193 <211> 111 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(930..1262) <400> 1193 Met Ser Val Ser Asn Met Pro Pro Ile Asp Arg Ala Glu Gln Ser Thr 1 5 10 15 Ala His Glu Ile Gln Gln Ala Lys Val Ile Asp Leu Asn Asp Arg Val 20 25 30 Leu Asn Leu Asp Asn Pro Asp Asp Lys Met Ile Ser Ala Phe Ala Asn 35 40 45 Tyr Ala Val Gln Thr Glu Asn Trp Gln Gln Asn Ala Leu Gln Ala Leu 50 55 60 Thr Ser Asp Lys Lys Gly Leu Thr Pro Glu Lys Leu Leu Val Leu Gln 65 70 75 80 Asp His Val Leu Asn Tyr Asn Val Glu Val Ser Leu Val Gly Thr Leu 85 90 95 Ala Arg Lys Ile Val Ala Ala Val Glu Thr Leu Thr Arg Ser * 100 105 110 <210> 1194 <211> 80 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1282..1521) <400> 1194 Met Ala Asp Trp Asn Gly Tyr Ile Met Asp Ile Ser Lys Gln Phe Asp 1 5 10 15 Gln Gly Val Asp Asp Leu Asn Gln Gln Val Glu Lys Ala Leu Glu Asp 20 25 30 Leu Ala Thr Asn Pro Ser Asp Pro Lys Phe Leu Ala Glu Tyr Gln Ser 35 40 45 Ala Leu Ala Glu Tyr Thr Leu Tyr Arg Asn Ala Gln Ser Asn Val Val 50 55 60 Lys Ala Tyr Lys Asp Leu Asp Ser Ala Ile Ile Gln Asn Phe Arg * 65 70 75 <210> 1195 <211> 245 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1535..2269) <400> 1195 Met Leu Phe Phe Leu Phe Val Ile Ile Phe Ile Ala Phe Tyr Ile Val 1 5 10 15 Asn Ala Ser Asn Asp Pro Gln Leu Arg His Ile Asp Lys Ile Leu Val 20 25 30 Asn Lys Asn Arg Asn Tyr Glu Ile Leu Tyr Gly Arg Asp His Val Ile 35 40 45 Tyr Ile Asn Thr Asn Ser Leu Asp Glu Ala Val Trp Val Lys Gln Ala 50 55 60 Leu Glu Lys Asn Gln Pro Gly Lys Pro Val Arg Val Ile Asn Pro Asp 65 70 75 80 Asp Glu Ser Ile Arg Ile Phe Ser Trp Leu Ala Asp Asn Phe Pro Asp 85 90 95 Leu Gln Tyr Phe Lys Leu Gln Leu Leu Asp Ala Ser Asn Pro Arg Leu 100 105 110 Thr Val Ser Lys Gln Arg Asn Ala Ile Thr Gln Gln Leu Ile Asp Asn 115 120 125 Leu Ile Lys Gly Leu Leu Gln Thr Met Pro Tyr Ala Ser Asn Ile Ser 130 135 140 Ile Ala Val Leu Asp Asp Asn Val Leu Glu Ser Gln Ala Ile Glu Thr 145 150 155 160 Leu Ser Ala Ile Gly Leu Ser Tyr Glu Lys Tyr Lys Thr Ala Asn Asn 165 170 175 Val Tyr Phe Asn Ile Ile Gly Thr Leu Ser Asp Ser Glu Leu Asn Lys 180 185 190 Ile Asn Asn Tyr Val Asp Glu Tyr Tyr Lys Gln Trp Gly Lys Gln Tyr 195 200 205 Val Arg Phe Asn Val Asn Leu Lys Asn Gln Asp Thr Asn Asn Ser Ser 210 215 220 Phe Ser Tyr Gly Asp Asn Arg Phe Glu Lys Ser Gln Gly Ser Lys Trp 225 230 235 240 Thr Phe Gln Glu * <210> 1196 <211> 167 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2973..3473) <400> 1196 Met Gln Val Phe Ser Ser Asp Val Tyr Phe Thr Val Gly Thr Asn Ala 1 5 10 15 Leu Leu Ala Ser Gln Lys Glu Tyr Tyr Ser Asp Leu Val Ala Leu Val 20 25 30 Asp Leu Gly His Ser Phe Val Val Ile Asp Glu His Gln His Arg Asn 35 40 45 Leu Lys Pro Asn Thr Glu Pro Val Asn Ile Leu Leu Ser Asn Asn Phe 50 55 60 Ile Trp Ile Asn Lys Asn Ile Thr Leu Ser Asp Leu Thr His Phe Leu 65 70 75 80 Val Ser Asn Leu His Thr Gln Asn Val Tyr Ser Thr Gln Glu Pro Leu 85 90 95 Thr His Asp Glu Ile Asp Ile Leu Arg Leu Cys Val Ser Tyr Ser Leu 100 105 110 Lys Gln Ile Ala Ile Ile Lys Gly Ile Asp Tyr Lys Thr Val Ser Tyr 115 120 125 His Lys Ile Arg Ala Leu Asn Gln Leu Asn Ile Lys Gly Thr Val Glu 130 135 140 Leu Phe Ile Ala Leu Cys Glu Trp Asp Lys His Tyr Phe Lys Leu Gln 145 150 155 160 Ser Cys Val Arg Glu Ser * 165 <210> 1197 <211> 374 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3830..4951) <400> 1197 Met Ala Asn Lys Thr Glu Lys Pro Thr Gln Lys Lys Leu Gln Asp Ala 1 5 10 15 Ser Lys Lys Gly Gln Ile Leu Lys Ser Arg Asp Leu Thr Val Ser Val 20 25 30 Ile Met Leu Val Gly Thr Leu Tyr Leu Gly Tyr Val Phe Asp Val His 35 40 45 His Ile Met Ser Ile Leu Glu Tyr Ile Leu Asp His Asn Ala Lys Pro 50 55 60 Asp Ile Trp Asp Tyr Phe Lys Ala Met Gly Ile Gly Trp Leu Lys Thr 65 70 75 80 Ile Ile Pro Phe Leu Leu Val Cys Met Phe Thr Thr Ile Leu Val Ser 85 90 95 Trp Phe Gln Ser Lys Met Gln Leu Ala Thr Glu Ala Val Lys Leu Lys 100 105 110 Phe Asp Ser Leu Asn Pro Val Asn Gly Leu Lys Arg Ile Phe Gly Leu 115 120 125 Lys Thr Val Lys Glu Phe Val Lys Ala Ile Leu Tyr Ile Ile Phe Phe 130 135 140 Ala Leu Glu Ile Lys Val Phe Trp Ser Asn His Lys Ser Leu Leu Phe 145 150 155 160 Lys Thr Leu Asp Gly Asp Ile Ile Ser Leu Leu Ser Asp Trp Gly Glu 165 170 175 Met Leu Phe Leu Leu Ile Leu Tyr Cys Leu Gly Ser Met Ile Ile Val 180 185 190 Leu Ile Phe Asp Phe Ile Ala Glu Tyr Phe Leu Phe Met Lys Asp Met 195 200 205 Lys Met Asp Lys Gln Glu Val Lys Arg Glu Tyr Lys Glu Gln Glu Gly 210 215 220 Asn Pro Glu Ile Lys Ser Lys Arg Arg Glu Arg His Gln Glu Ile Leu 225 230 235 240 Ser Glu Gln Leu Lys Ser Asp Val Ser Asn Ser Arg Leu Met Ile Ala 245 250 255 Asn Pro Thr His Ile Ala Ile Gly Ile Tyr Phe Lys Pro His Leu Ser 260 265 270 Pro Ile Pro Leu Ile Ser Val Arg Glu Thr Asn Glu Val Ala Leu Ala 275 280 285 Val Arg Lys Tyr Ala Lys Glu Ile Gly Ile Pro Ile Ile Thr Asp Lys 290 295 300 Lys Leu Ala Arg Lys Ile Tyr Ala Thr His Arg Arg Tyr Asp Tyr Val 305 310 315 320 Ser Phe Glu Asn Ile Asp Glu Ile Leu Arg Leu Leu Leu Trp Leu Glu 325 330 335 Asp Val Glu Asn Ala Gly Gln Pro Val Pro Asp Glu Gln Leu Ser Ser 340 345 350 Glu Asp Lys Tyr Ile Glu Gly Glu Asp Thr Lys Ser Glu Asn Asn Asp 355 360 365 Asn Asn Leu Lys Asn * 370 <210> 1198 <211> 79 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4960..5196) <400> 1198 Met Thr His Thr Ile Val Tyr Ala Ser Pro Val Ile Ala Val Met Leu 1 5 10 15 Gly Gly Glu Ala Val Leu Gly Leu Leu Ala Arg Tyr Ala Ser Gln Leu 20 25 30 Asn Ala Phe Ala Ile Ser Leu Thr Val Lys Ser Ala Leu Ala Phe Leu 35 40 45 Ile Leu Ile Ile Tyr Phe Gly Pro Ile Leu Ala Glu Arg Val Met Pro 50 55 60 Leu Ser Phe Phe Pro Glu Gln Leu Gln Leu Tyr Ile Glu Lys * 65 70 75 <210> 1199 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5275..5742) <400> 1199 Leu Arg Glu Asp Ser Met Gly Glu Val Ile Leu Tyr Gln Leu His Ser 1 5 10 15 Leu Leu Ala Ala Thr Ala Leu Gly Phe Cys Arg Leu Ala Pro Thr Phe 20 25 30 Tyr Leu Leu Pro Phe Phe Ala Ser Gly Asn Ile Pro Thr Val Val Arg 35 40 45 His Pro Ile Ile Ile Val Val Ser Cys Ala Leu Val Gln His Tyr His 50 55 60 Tyr Glu Leu Ser Thr Leu Asn Glu Ile Asp Ile Ala Leu Leu Ala Ala 65 70 75 80 Arg Glu Ile Ile Ile Gly Leu Phe Ile Ala Cys Leu Leu Ala Ser Pro 85 90 95 Phe Trp Ile Phe Leu Ala Ile Gly Ser Phe Ile Asp Asn Gln Arg Gly 100 105 110 Ala Thr Leu Ser Ser Thr Leu Asp Pro Ala Thr Gly Val Asp Thr Ser 115 120 125 Glu Leu Ala Arg Leu Phe Asn Leu Phe Ser Ala Ala Val Tyr Leu Thr 130 135 140 Asn Gly Gly Leu Asn Phe Ile Leu Glu Thr Leu * 145 150 155 <210> 1200 <211> 87 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5729..5989) <400> 1200 Met Asp Asp Ile Val Phe Ala Gly Asn Arg Ala Leu Tyr Leu Ile Leu 1 5 10 15 Val Met Ser Ala Gly Pro Ile Ala Val Ala Thr Phe Val Gly Leu Leu 20 25 30 Val Gly Leu Phe Gln Thr Val Thr Gln Leu Gln Glu Gln Thr Leu Pro 35 40 45 Phe Gly Val Lys Leu Leu Cys Val Ser Ile Cys Phe Phe Leu Met Ser 50 55 60 Gly Trp Tyr Gly Glu Lys Leu Tyr Ser Phe Gly Ile Glu Met Leu Asn 65 70 75 80 Leu Ala Phe Ala Arg Gly * 85 <210> 1201 <211> 222 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6000..6665) <400> 1201 Met Ser Asn Ser Ile Ser Leu Ile Ala Ile Leu Ser Leu Phe Thr Leu 1 5 10 15 Leu Pro Phe Ile Ile Ala Ser Gly Thr Cys Phe Ile Lys Phe Ser Ile 20 25 30 Val Phe Val Ile Val Arg Asn Ala Leu Gly Leu Gln Gln Val Pro Ser 35 40 45 Asn Met Thr Leu Asn Gly Val Ala Leu Leu Leu Ser Met Phe Val Met 50 55 60 Met Pro Val Gly Lys Glu Ile Tyr Tyr Asn Ser Gln Asn Glu Asn Leu 65 70 75 80 Ser Phe Asn Asn Val Ala Ser Val Val Asn Phe Val Glu Thr Gly Met 85 90 95 Ser Gly Tyr Lys Ser Tyr Leu Ile Lys Tyr Ser Glu Pro Glu Leu Val 100 105 110 Ser Phe Phe Glu Lys Ile Gln Lys Val Asn Ser Ser Glu Asp Asn Glu 115 120 125 Glu Ile Ile Asp Asp Asp Asn Ile Ser Ile Phe Ser Leu Leu Pro Ala 130 135 140 Tyr Ala Leu Ser Glu Ile Lys Ser Ala Phe Ile Ile Gly Phe Tyr Ile 145 150 155 160 Tyr Leu Pro Phe Val Val Val Asp Leu Val Ile Ser Ser Val Leu Leu 165 170 175 Thr Leu Gly Met Met Met Met Ser Pro Val Thr Ile Ser Thr Pro Ile 180 185 190 Lys Leu Ile Leu Phe Val Ala Met Asp Gly Trp Thr Met Leu Ser Lys 195 200 205 Gly Leu Ile Leu Gln Tyr Phe Asp Leu Ser Ile Asn Pro * 210 215 220 <210> 1202 <211> 329 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6655..7641) <400> 1202 Met Lys Ala Asn Ser Lys Thr Ile Arg Arg Met Lys Val Asn Val Arg 1 5 10 15 Ser Glu Glu Ser Lys Ser Lys His Ser Thr Phe Glu Thr Thr Phe Gln 20 25 30 Asn Trp Lys Glu Asn Gly Glu Asp Val Ala Leu Leu Met Pro Glu Phe 35 40 45 Ser Ala Lys Trp Leu Pro Ile Ala Glu Glu Ser Gly Ser Trp Ser Gly 50 55 60 Trp Val Leu Leu Arg Glu Ile Phe Pro Leu Ile Ser Ala Glu Leu Ala 65 70 75 80 Gly Met Ala Leu Met Pro Glu Thr Glu Arg Leu Ile Gly Glu Trp Leu 85 90 95 Ser Leu Ser Ser Ser Pro Leu Asn Leu Lys Tyr Pro Glu Leu Lys Tyr 100 105 110 Asn Arg Leu Cys Val Gly Lys Val Phe Asp Gly Val Leu Ser Pro Ala 115 120 125 Gln Pro Leu Ile Arg Ile Trp Thr Gly Glu Leu Asn Leu Trp Leu Asp 130 135 140 Lys Val Thr Val Cys Gln Tyr Glu Asn Ala Pro Thr Leu Asp Lys Lys 145 150 155 160 Ser Leu Tyr Trp Pro Ile His Phe Val Ile Gly Phe Ser Lys Thr Cys 165 170 175 Tyr Arg Thr Ile Val Asp Ile Glu Val Gly Asp Val Leu Leu Ile Ser 180 185 190 Asn Asn Met Ala Tyr Ala Val Ile Tyr Asn Thr Lys Ile Cys Asp Leu 195 200 205 Ile Tyr Pro Glu Glu Leu Lys Met Ala Asp His Phe Gln Tyr Glu Glu 210 215 220 Asp Phe Glu Thr Asp Asp Phe Asp Ile Lys Lys Ser Glu Ser Glu Ile 225 230 235 240 Tyr Asp Glu Asn Asp Glu Gln Met Ile Asn Ser Phe Glu Glu Leu Pro 245 250 255 Val Lys Ile Glu Phe Val Leu Gly Lys Lys Ile Met Asn Leu Tyr Glu 260 265 270 Ile Asp Glu Leu Cys Ala Lys Arg Ile Ile Ser Leu Leu Pro Glu Ser 275 280 285 Glu Lys Asn Ile Glu Ile Arg Val Asn Gly Ala Leu Thr Gly Tyr Gly 290 295 300 Glu Leu Val Glu Val Asp Asp Lys Leu Gly Val Glu Ile His Ser Trp 305 310 315 320 Leu Ser Gly His Asn Asn Val Lys * 325 <210> 1203 <211> 206 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7601..8218) <400> 1203 Leu Gln Thr Lys Gly Ala Glu Gln Phe Ser Thr Lys Lys Leu Leu Asn 1 5 10 15 Met Thr Ser Arg Asp Gln Gly Ile Asn Ser Glu Leu Ser Asn Arg Thr 20 25 30 Ile Gln Phe Lys Glu Lys Ile His Asn Gly Ile His Thr Glu Tyr Ile 35 40 45 Thr Asp Gln Lys His Ser Asn Asn Lys Asp Arg Glu Lys Lys Tyr Arg 50 55 60 Asp Gly Asp Lys Ile Asn Gly Pro Gln Ala His Ser Leu Asp Ile Thr 65 70 75 80 Asn Glu Arg Arg Phe Ala Asp Asn Arg Thr Met Phe Thr Gln His Ile 85 90 95 Glu Lys Gln Arg Asn Val Asn Thr Leu Asn Gln Asn Asp Ile Asn Asn 100 105 110 Ser Ala Asn Asn Ala Asn Val Arg Glu Asn Glu Leu Thr Tyr Gln Phe 115 120 125 Gln Arg Trp Gly Gln Asn His Thr Val Arg Ile Leu Glu Ser Ser Glu 130 135 140 Gly Ile Arg Leu Lys Pro Ser Asp Thr Leu Val Ser Asp Arg Leu His 145 150 155 160 Glu Ala Gln His Asn Asp Val Thr Ala Gln Arg Trp Val Leu Thr Glu 165 170 175 Gln Asp Glu Arg Gln Gly Gln Arg His Gln Pro His Glu Glu Gln Glu 180 185 190 Asn Glu Gly Lys Phe Glu Asn Asp Gln Lys Asp Glu Ser * 195 200 205 <210> 1204 <211> 78 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8243..8476) <400> 1204 Met Asp Glu Val Lys Lys Ile Glu His Cys Lys Ile Leu Asn Thr Asp 1 5 10 15 Thr Pro Asp Asn Ser Ala Ser Asp Leu Asp Ser Phe Leu Lys Lys Asn 20 25 30 Lys Lys Asn Lys Glu Met Ser Glu Ile Val Ala Gly Thr Ile Leu Gln 35 40 45 Leu Leu Arg Gln Thr Gln Asp Asn Gln Phe Ser Thr Leu Gly Lys Lys 50 55 60 Asn Gly His Met Lys Ser Ile Asp Asn Lys Ser Ser Leu * 65 70 75 <210> 1205 <211> 112 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8454..8789) <400> 1205 Met Gln Leu Lys Asn Leu Gln Ser Leu Leu Asp Met Lys Glu Leu Leu 1 5 10 15 Gly Glu Val Val Phe Arg Gln Asp Ile Phe Tyr Ser Leu Arg Lys Val 20 25 30 Thr Val Ile Gln Gln Gln Ile Ala Glu Ile Asn Leu Glu Lys Gln Lys 35 40 45 Ile Ala Glu Arg Arg Lys Ile Leu Asn Lys Glu Ile Val Gln Gln Gln 50 55 60 Ala Gln Arg Lys His Trp Trp Leu Lys Gly Glu Lys Tyr Asp Arg Leu 65 70 75 80 Lys Lys Arg Ile Lys Lys Gln Leu Leu Asn Gln Met Leu Tyr Gln Asp 85 90 95 Glu Leu Glu Gln Glu Glu Lys Tyr Asn Gly Arg Ser Gln Glu Asn * 100 105 110 <210> 1206 <211> 431 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8902..10194) <400> 1206 Met Lys Lys Leu Lys Leu Leu Asn Lys Tyr Ser Tyr Leu His Ser Ile 1 5 10 15 Asn Gly Ser Leu Ile Glu Ala Glu Leu Asp Asp Val Ser Val Gly Glu 20 25 30 Val Cys Glu Ile Tyr Ala Ser Arg Gln Ala Asn Glu Arg Ile Ala Arg 35 40 45 Ala Gln Val Val Gly Phe Arg Asn Gly Lys Thr Leu Leu Asn Leu Ile 50 55 60 Gly Ser Ser Val Gly Leu Thr Arg Thr Ala Val Leu Lys Pro Thr Gly 65 70 75 80 Glu Gln Leu Thr Ile Gln Ile Ser Asp Ala Phe Leu Gly Ser Val Leu 85 90 95 Asn Ala Ser Gly Gln Ile Met Glu Arg Phe Val Pro Asp Thr Pro Gly 100 105 110 Asp Arg Gly Asn Leu Arg Leu Ile Asp Glu Leu Pro Pro Ser Tyr Gln 115 120 125 Glu Arg Arg Val Ile Asn Thr Pro Leu Glu Thr Arg Ile Arg Val Ile 130 135 140 Asp Gly Val Leu Thr Cys Gly Ile Gly Gln Arg Val Gly Ile Phe Ala 145 150 155 160 Ser Ala Gly Cys Gly Lys Thr Val Leu Met His Met Leu Val Asn Asn 165 170 175 Thr Glu Ala Asp Val Phe Val Ile Gly Leu Ile Gly Glu Arg Gly Arg 180 185 190 Glu Val Thr Glu Cys Ala Glu Ser Leu Lys Lys Ser Val Asn Ala Ala 195 200 205 Lys Cys Val Leu Val Tyr Ala Thr Ser Asp Phe Ser Ser Val Asp Arg 210 215 220 Cys Asn Ala Ala Leu Met Ala Thr Thr Val Ala Glu Tyr Phe Arg Asp 225 230 235 240 Arg Gly Lys Arg Val Val Leu Phe Ile Asp Ser Met Thr Arg Tyr Ala 245 250 255 Arg Ala Leu Arg Asp Met Lys Leu Ala Ala Gly Glu Pro Pro Ala Arg 260 265 270 Arg Gly Tyr Pro Ala Ser Val Phe Asp Ser Leu Pro Arg Leu Leu Glu 275 280 285 Arg Pro Gly Pro Thr Leu Lys Gly Ser Ile Thr Glu Phe Tyr Thr Val 290 295 300 Leu Leu Glu Gly Glu Asp Glu Ser Asp Pro Leu Gly Asp Glu Ile Arg 305 310 315 320 Ser Ile Leu Asp Gly His Ile Tyr Leu Ser Arg Lys Leu Ala Gly Gln 325 330 335 Gly His Tyr Pro Ala Ile Asp Val Leu Lys Ser Val Ser Arg Val Phe 340 345 350 Gly Gln Val Thr Asp Glu Lys His Arg Asp Asn Ala Ala Arg Val Arg 355 360 365 Lys Asn Leu Thr Thr Leu Glu Asp Leu Gln Val Phe Ile Asp Leu Gly 370 375 380 Glu Tyr Arg Ala Gly Gln Asn Ala Glu Asn Asp Phe Ala Met Asn Ala 385 390 395 400 Arg Pro Lys Leu Thr Asn Trp Leu Lys Gln Ser Val Asn Glu Lys Met 405 410 415 Pro Met Ser Glu Thr Leu Lys Glu Leu Glu Arg Ile Val Lys * 420 425 430 <210> 1207 <211> 687 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10226..12286) <400> 1207 Met Phe Asn Lys Val Leu Val Gly Leu Arg Ser His Pro Glu Leu Ile 1 5 10 15 Ile Leu Gly Leu Met Val Met Ile Ile Ala Met Leu Ile Ile Pro Leu 20 25 30 Pro Thr Tyr Leu Ile Asp Phe Leu Ile Gly Leu Asn Leu Thr Leu Ala 35 40 45 Ile Leu Val Phe Leu Gly Ser Phe Tyr Val Asp Arg Ile Leu Ser Phe 50 55 60 Ser Ser Phe Pro Ser Ile Leu Leu Ile Thr Thr Leu Phe Arg Leu Ala 65 70 75 80 Leu Ala Ile Ser Thr Ser Arg Leu Ile Leu Leu Glu Ala Asp Ala Gly 85 90 95 Glu Ile Ile Thr Ser Phe Gly Glu Phe Val Ile Gly Asp Ser Leu Val 100 105 110 Val Gly Phe Val Ile Phe Ser Ile Val Thr Ile Val Gln Phe Ile Val 115 120 125 Ile Thr Lys Gly Ser Glu Arg Val Ala Glu Val Ala Ala Arg Phe Ser 130 135 140 Leu Asp Gly Met Pro Gly Lys Gln Met Ser Ile Asp Ala Asp Leu Arg 145 150 155 160 Ala Gly Ile Ile Asp Ala Asp Leu Ala Lys Glu Arg Arg Ser Val Leu 165 170 175 Glu Arg Glu Ser Gln Leu Tyr Gly Ser Phe Asp Gly Ala Met Lys Phe 180 185 190 Ile Lys Gly Asp Ala Ile Ala Asn Ile Ile Ile Ile Phe Val Asn Ile 195 200 205 Ile Gly Gly Leu Ser Val Gly Val Gly Gln Asn Gly Met Asp Phe Ser 210 215 220 Thr Ala Leu Thr Val Tyr Thr Ile Leu Thr Val Gly Asp Gly Leu Val 225 230 235 240 Ser Gln Ile Pro Ala Leu Leu Ile Ala Ile Ser Ala Gly Phe Ile Val 245 250 255 Thr Arg Val Asn Gly Asp Ser Asp Asn Met Gly Gln Asn Ile Met Ser 260 265 270 Gln Leu Leu Ser Asn Ser Phe Val Ile Val Val Thr Cys Val Leu Ala 275 280 285 Leu Ser Ile Gly Leu Leu Pro Gly Phe Pro Leu Leu Val Phe Leu Cys 290 295 300 Leu Ala Val Ile Leu Gly Ile Tyr Phe Tyr Phe Lys Phe Lys Lys Lys 305 310 315 320 Gly Thr Glu Glu Thr Val Val Glu Gly Asp Ile Thr Val Gly Leu Glu 325 330 335 Pro Tyr Asn Gln Asp Asp Asp Ile Ser Leu Gly Ile Ile Asn Lys Leu 340 345 350 Asp Gln Val Ile Thr Glu Thr Val Pro Leu Val Leu Ile Met Asn Ser 355 360 365 Val Gln Ala Lys Lys Tyr Thr Glu Ile Asn Leu Ala Asp Arg Ile Arg 370 375 380 Ser Gln Phe Phe Ile Glu Tyr Gly Ile Arg Ile Pro Gly Ile Val Ile 385 390 395 400 Arg Glu Gly Glu Gly Leu Asn Asp Glu Asp Val Ile Leu Met Leu Asn 405 410 415 Glu Val Arg Ala Ser Gln Phe Lys Ile Tyr His Asp Leu Val Leu Leu 420 425 430 Val Glu Tyr Ser Asp Glu Val Val Ser Thr Leu Ile Lys Lys Pro Val 435 440 445 Ile Val Asn Ser Asn Gly Glu Gln Tyr Tyr Trp Val Thr Lys Ser Asp 450 455 460 Ala Gln Lys Leu Thr Lys Ile Gly Cys Tyr Thr Arg Thr Ala Met Asp 465 470 475 480 Glu Met Tyr Asn His Leu Ser Val Cys Leu Ala His Asn Ile Asn Glu 485 490 495 Tyr Phe Gly Ile Gln Glu Thr Lys Tyr Ile Leu Asp Gln Leu Glu Met 500 505 510 Lys Tyr Ser Asp Leu Leu Lys Glu Ile Leu Arg Tyr Ile Thr Val Gln 515 520 525 Arg Ile Ser Glu Val Ile Gln Arg Leu Ile Gln Glu Arg Ile Ser Val 530 535 540 Arg Asn Met Arg Leu Val Met Glu Ala Leu Ala Leu Trp Ser Pro Arg 545 550 555 560 Glu Lys Asp Ile Ile Thr Leu Val Glu His Val Arg Gly Ala Leu Gly 565 570 575 Arg Tyr Ile Cys His Lys Phe Ser Tyr Ser Gly Glu Ile Lys Ala Ile 580 585 590 Val Ile Ser Pro Glu Ile Glu Asp Arg Ile Arg Asp Gly Val Arg Pro 595 600 605 Thr Ala Gly Gly Thr Phe Leu Asn Leu Asp Ala Ser Glu Ala Glu Met 610 615 620 Ile Leu Asp Asn Phe Lys Leu Ala Leu Ser Gly Ile Asn Ile Pro Ile 625 630 635 640 Lys Asp Ile Ile Leu Leu Gly Ser Val Asp Ile Arg Arg Phe Ile Lys 645 650 655 Lys Leu Ile Glu Ser Ser Tyr Arg Asp Leu Glu Val Leu Ser Tyr Gly 660 665 670 Glu Leu Thr Glu Asn Val Pro Val Asn Ile Leu Lys Thr Ile * 675 680 685 <210> 1208 <211> 382 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12279..13424) <400> 1208 Met Ala Ile His Val Glu His Val Gly Val Leu Glu Arg Ala Arg Glu 1 5 10 15 Val Ser Arg Leu Glu Asp Ile Ile Thr Glu Asp Asn Glu Asp Ile Glu 20 25 30 Ala Glu Met Pro Lys Met Arg Asp Asp Pro Ala Gly Lys Glu Ala Arg 35 40 45 Phe Leu Gln Ala Thr Asp Glu Met Ser Ala Ala Leu Thr Gln Phe Met 50 55 60 Lys Lys Lys Ile Tyr Glu Glu Gln Leu Ala Asn Phe Leu Asp Gly Glu 65 70 75 80 Glu Tyr Val Leu Glu Asp Gln Pro Ile Glu Lys Thr Asp Lys Val Met 85 90 95 Glu Ala Leu Lys Ala Ala Thr Thr His Asp Tyr Glu Val Tyr Ser Phe 100 105 110 Ala Lys Lys Leu Phe Pro Asp Glu Ser Asp Leu Val Val Val Leu Arg 115 120 125 Ala Ile Leu Arg Lys Lys Gln Ile Ser Glu Asn Val Arg Leu Asn Ala 130 135 140 Glu Ala Leu Leu Arg Lys Val Asn Gln Glu Thr Thr Lys Lys Phe Ile 145 150 155 160 Asn Ser Gly Ile Asn Ser Ala Leu Lys Ala Lys Leu Phe Gly Gln Ala 165 170 175 Leu Ser Leu Asn Pro Lys Leu Leu Arg Ala Ser Tyr Arg Gln Phe Leu 180 185 190 Met Ala Glu Asp Asp Ala Val Asp Thr Tyr Val Glu Trp Ile Gly Ser 195 200 205 Tyr Gly Tyr Gln Asn Arg Met Leu Val Thr Lys Phe Ile Lys Glu Thr 210 215 220 Leu Phe Ser Asp Ile Asn Ala Leu Asp Ala Ser Cys Ser Ser Leu Glu 225 230 235 240 Phe Gly Met Phe Leu Asn Lys Leu Ser Gln Leu Leu Ser Leu Gln Ser 245 250 255 Ala Glu Ala Leu Phe Leu Lys Thr Leu Met Asn Asn Pro Ile Ile Lys 260 265 270 Lys Phe Ile Ser Ala Glu Asp Tyr Trp Ile Phe Phe Leu Ile Ser Leu 275 280 285 Ile Lys Phe Pro Glu Thr Ala Glu Glu Leu Leu Asn Asn Ala Leu Val 290 295 300 Thr Leu Pro Ala Asp Ala Asn Tyr Lys Asp Lys Thr Leu Leu Leu Lys 305 310 315 320 Ala Ile Tyr Ser Gly Cys Thr Asn Leu Pro Phe Ser Leu Phe Ile Asn 325 330 335 Asn Glu Gln Leu Leu Glu Ile Arg Glu Cys Cys Lys Gln Ala Ile Lys 340 345 350 Val Thr Phe Ala Ala Glu Leu Phe Asp Thr Gln Asn Cys Asn Lys Lys 355 360 365 Gln Asn Lys Lys Pro Trp Lys Lys Val Met Phe Asn Val * 370 375 380 <210> 1209 <211> 568 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13429..15132) <400> 1209 Met Lys Ile Lys Leu Arg Ile Thr Ile Ile Leu Ile Ser Val Leu Cys 1 5 10 15 Ile Phe Asn Gly Leu Leu Thr Pro Gly Ala Tyr Ala Ala Ala Ala Asn 20 25 30 Gly Tyr Val Ala Asn Lys Glu Asn Leu Arg Ser Phe Phe Glu Thr Val 35 40 45 Ser Ser Tyr Ala Gly Lys Pro Thr Ile Val Ser Lys Leu Ala Met Lys 50 55 60 Lys Gln Ile Ser Gly Asn Phe Asp Leu Thr Glu Pro Tyr Ala Leu Ile 65 70 75 80 Glu Arg Leu Ser Ala Gln Met Gly Leu Ile Trp Tyr Asp Asp Gly Lys 85 90 95 Ala Ile Tyr Ile Tyr Asp Ser Ser Glu Met Arg Asn Ala Leu Ile Asn 100 105 110 Leu Arg Lys Val Ser Thr Asn Glu Phe Asn Asn Phe Leu Lys Lys Ser 115 120 125 Gly Leu Tyr Asn Ser Arg Tyr Glu Ile Lys Gly Asp Gly Asn Gly Thr 130 135 140 Phe Tyr Val Ser Gly Pro Pro Val Tyr Val Asp Leu Val Val Asn Ala 145 150 155 160 Ala Lys Leu Met Glu Gln Asn Ser Asp Gly Ile Glu Ile Gly Arg Asn 165 170 175 Lys Val Gly Ile Ile His Leu Val Asn Thr Phe Val Asn Asp Arg Thr 180 185 190 Tyr Glu Leu Arg Gly Glu Lys Ile Val Ile Pro Gly Met Ala Lys Val 195 200 205 Leu Ser Thr Leu Leu Asn Asn Asn Ile Lys Gln Ser Thr Gly Val Asn 210 215 220 Val Leu Ser Glu Ile Ser Ser Arg Gln Gln Leu Lys Asn Val Ser Arg 225 230 235 240 Met Pro Pro Phe Pro Gly Ala Glu Glu Asp Asp Asp Leu Gln Val Glu 245 250 255 Lys Ile Ile Ser Thr Ala Gly Ala Pro Glu Thr Asp Asp Ile Gln Ile 260 265 270 Ile Ala Tyr Pro Asp Thr Asn Ser Leu Leu Val Lys Gly Thr Val Ser 275 280 285 Gln Val Asp Phe Ile Glu Lys Leu Val Ala Thr Leu Asp Ile Pro Lys 290 295 300 Arg His Ile Glu Leu Ser Leu Trp Ile Ile Asp Ile Asp Lys Thr Asp 305 310 315 320 Leu Glu Gln Leu Gly Ala Asp Trp Ser Gly Thr Ile Lys Ile Gly Ser 325 330 335 Ser Leu Ser Ala Ser Phe Asn Asn Ser Gly Ser Ile Ser Thr Leu Asp 340 345 350 Gly Thr Gln Phe Ile Ala Thr Ile Gln Ala Leu Ala Gln Lys Arg Arg 355 360 365 Ala Ala Val Val Ala Arg Pro Val Val Leu Thr Gln Glu Asn Ile Pro 370 375 380 Ala Ile Phe Asp Asn Asn Arg Thr Phe Tyr Thr Lys Leu Val Gly Glu 385 390 395 400 Arg Thr Ala Glu Leu Asp Glu Val Thr Tyr Gly Thr Met Ile Ser Val 405 410 415 Leu Pro Arg Phe Ala Ala Arg Asn Gln Ile Glu Leu Leu Leu Asn Ile 420 425 430 Glu Asp Gly Asn Glu Ile Asn Ser Asp Lys Thr Asn Val Asp Asp Leu 435 440 445 Pro Gln Val Gly Arg Thr Leu Ile Ser Thr Ile Ala Arg Val Pro Gln 450 455 460 Gly Lys Ser Leu Leu Ile Gly Gly Tyr Thr Arg Asp Thr Asn Thr Tyr 465 470 475 480 Glu Ser Arg Lys Ile Pro Ile Leu Gly Ser Ile Pro Phe Ile Gly Lys 485 490 495 Leu Phe Gly Tyr Glu Gly Thr Asn Ala Asn Asn Ile Val Arg Val Phe 500 505 510 Leu Ile Glu Pro Arg Glu Ile Asp Glu Arg Met Met Asn Asn Ala Asn 515 520 525 Glu Ala Ala Val Asp Ala Arg Ala Ile Thr Gln Gln Met Ala Lys Asn 530 535 540 Lys Glu Ile Asn Asp Glu Leu Leu Gln Lys Trp Ile Lys Thr Tyr Leu 545 550 555 560 Asn Arg Glu Val Val Gly Gly * 565 <210> 1210 <211> 250 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(15129..15878) <400> 1210 Met Ile Glu Glu Gly Leu Leu Leu Pro Met Asn Val Leu Leu Gln Gly 1 5 10 15 Gln Lys Leu Thr Leu Leu Asp Pro Glu Met Trp Phe Leu Arg Gly Asn 20 25 30 Glu Asn Lys Asp Val Thr Leu Val Ile Thr Ile Gly Asn Asn His Gln 35 40 45 Lys Leu Met Val Val Glu Asp Ile Leu Leu Leu Ile Asp Arg Ser Gln 50 55 60 Ile Glu Val Thr Ala Gly Lys Val Ile Tyr His Pro Leu Arg Ile Asp 65 70 75 80 Ile Leu Ser Lys Leu Leu Ala Phe Ile Asp Glu Ser Thr Gly Ser Val 85 90 95 Glu Arg Glu His His Glu Leu Phe Ala Asp Ala Leu Pro Phe Ala Ser 100 105 110 Glu Val Val Leu Phe Ser Lys Val Ala Ser Glu Ala Trp Phe Leu Ala 115 120 125 Thr Tyr Leu Ser Ser Asp Asn Ile Asn Glu Ile Leu Phe Gln His Leu 130 135 140 Arg Lys Thr Glu Cys Tyr Lys Leu Val Arg Tyr Leu Leu Ser Gln Ser 145 150 155 160 Leu Ile His Thr Ser Leu Tyr Asp Leu Gly Glu Leu Tyr Gly Val Ser 165 170 175 Tyr Ser His Phe Arg Arg Leu Cys Ser Tyr Ala Leu Gly Gly Lys Val 180 185 190 Lys Thr Glu Leu Cys Gly Trp Arg Val Ala Arg Ala Val Leu Glu Ile 195 200 205 Ile Glu Gly Asn Ser Asp Met Thr Thr Ile Ala His Lys Tyr Gly Tyr 210 215 220 Ser Ser Ser Ser His Phe Ser Ala Glu Val Lys Ser Arg Leu Gly Lys 225 230 235 240 Thr Pro Arg Glu Leu Cys Lys Lys Leu * 245 <210> 1211 <211> 60 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(16224..16403) <400> 1211 Val Ile Asn Lys Leu Leu Leu Ala Tyr Leu Ile Gly Leu Val Val Thr 1 5 10 15 Ser Thr Leu Ile Phe Ile Phe Ser Glu Glu Lys Val Thr Tyr Arg Leu 20 25 30 Phe Ala Ala Ile Ile Thr Gly Leu Thr Trp Pro Leu Ser Leu Ile Pro 35 40 45 Ser Ile Ile Ser Leu Met Ile Arg Lys Ser Asp * 50 55 <210> 1212 <211> 15463 <212> DNA <213> Escherichia coli O157:H7 <400> 1212 ggacatattt tatcaattag tgttttttgc cgtttcataa tgtttcagat tgttcattat 60 gtttttgatt ataaacagat ttgtgatttt ccttgttcca gcttgtttca cgttgtagcc 120 ctttgtgcaa cgatcggtgt agttaatggt gtagttaatt gtgatgaccg gaatcaaaat 180 tatgagcaga gcacttaaca aactgagcga tacacagctg aggaaaatca acggcacacc 240 cgcccaaaaa acagcctttc ttaatgacgg tggaaacctg agcgtcaggc attcaaccag 300 tggcctttta acctggtatt tcacttacag ggccggaacg ggaagggggg caccaccgga 360 acgcattaag ctgggaaatt atcctgatct gagcctgaaa tcagccaggg aaaaagccgc 420 ccagtgtcgc gcatggctgg cagaggggaa aaatccacgt catgagctta attacaccgt 480 acaggaagcg ttaaagccgg taacggttgg cgatgcgctc acctactggc ttgagtcgta 540 cgcaaaggaa aaccgcgtgg attatgccgc cctgaaaaag cgccttaata atcacgtaat 600 acagcacatt ggtgctatgc cgctggataa atgcgagcta cggcactggc tggcctgttt 660 tgaccaggtg gcaaagcgaa cgcctgttac tgccggattc ttgctacaga cgtgcaaaca 720 ggcgcttaag ttctgccgga ggcggcgcta tgcaatcagc aacgttcttg atgatatgag 780 tgtggcggac gttgggaaaa aaccggatat aagcgagcgt gtcttaagca ccaaagaact 840 gggcgaatta ttgcaggcac tggacaaaaa aatattctcc ccctactaca tcgcgttaat 900 ccgcctcctg attgtgttcg gatgccggac ggtagaactg aggttatcgg agatcagcga 960 gtgggatttt accgaaatgc tctggaccgt gccgaaagaa cacagcaaaa cgaaggtggc 1020 aatattccgg cccataccgg aagcaatact gccgttcgtc acgcagctgg tggagcagaa 1080 caggcacacg ggtttattgc tgggggaagt gaaacaggaa acaagcgtgt cgcagtacgg 1140 cagattagcg cataggaggc taaatcaccc tcactggtca ctacatgaca tccggcgcac 1200 ctttacaacg atgctgaacg atttaggcgt ggatcctcac gtcgtggagc agcttacagg 1260 ccaccagatg ccaggaatgc agcgagttta taatcattcc cgttatctgg atgctaaacg 1320 caatgcgctg gatatgtgga cggagcggtt agggatactg gcgggaacac atgaaaacgt 1380 aaccacgcta ccagtagcca gaagaaaata atttttttcg tgttttttca gcatgcgcat 1440 actggatatg cgaacagata caacgtgcag caatgagcaa caatgtggaa caaccacgaa 1500 caagaggcga aaaagcgtac ggatttataa gtagctgatt tttaatgtgt tactggtttt 1560 ttatacacta gcgaatcact ctttaaagag cgagaaaaaa ggcatgaaac aatattttat 1620 gcctttgtat taacatgaat ttaaaagatt ttattcttac tgtttcattt tctgtaaatc 1680 atacatcctc agtatttgcc attcatcact ctagcgggaa caatacgaca caataagaca 1740 cctgatgact ctttaagaaa cgaaaggggg caatagtgtt aagcactgat cggtttatac 1800 gtgaaaaaga atgcgaaaaa ctaaccggcc ttagccgtac gtgtcgctac cgcctggaaa 1860 aggccggaca attcccatca cgtcgtaaac ttggcggtcg ttccgttggc tggtctttat 1920 ccgaggttct ggcctggaag gatagctgca aggcagttca ttaatcacgc tggcggcacg 1980 cagccgccac acatcaatca tctgaacaca gagctataac catgaagatt gaatatacgc 2040 cagaacgtgg gcggggattc gttcgccctg gtgaaactga aaaacaacaa aattggggtt 2100 tttcaggtat aaaaaaagcg gccccgaaat ggagccgcct ttctgaacag ataacccgct 2160 gcgccgtttg tgtgtgtgat cccaaacata agcacgggga tgatagccgc tatcaggctg 2220 gtgggcaatg caatcagtct ggttcagttc gttgccatac ctgcaatgag cgcttttccc 2280 tgtactcttt aaggaattgc tcaagggcaa aagcacatgg tgcgaatctt tctgattcat 2340 gctctatctt tctgcgccgt cttttccgtg ccggtgataa tgttttggtc aattctttat 2400 cggtcattgt gttgtcctgc atagcaatgc gccgtaatac ctcacaccac ggcgctgata 2460 gtttttatcc tttgggttct ataccgcgcc gctttagttc agtacgcccc aactctttaa 2520 gccagttggc taggcttatg ccgtcgctct gtgcttcttt atcgaattgc tcttttagct 2580 ctggagaaat tcgcattctg aattgtgggg attgcccgtc ccctttaggg cttttatcgc 2640 gtttgattgt tgacaagtgg tcacctattg aattagcctt tctattgtta ggtggtcacc 2700 ttaacacaag agcacttaaa aaagcaaagc cccgcaagtg tcattaccac tcgcagggct 2760 tctaaccaac aacgtaaact aggagccgtt atggttgctg taaatcatat accacacctt 2820 gtacacacac aaacggcctt tgtgtggcgt tttctggcac tgagtgccgg agaatctcaa 2880 atcatccacg taaccgcctg gacggaacgc gaagcgcgta gccgttgccc gtcaggttgt 2940 gttgctgtat ttgccgcccg tattcgtcag ggggtgtgcc atgcttaaaa ccttccgtgt 3000 atttgccagc gctgttaacc cactaggcca cacaattggt atcgctcaga atgtgaaggc 3060 tgttaatgtt cagacggcta ttgctgcggt gagaagcgaa tcatcagaat atggcttatc 3120 acaagtcatt atttcagcag tgtatgaatt aaaagaggtg cattaatgaa ggaaattaca 3180 ttacacgaag ccgctgaacg tgcgcaccag acagaaatta tttgccgcct tcttgaggta 3240 taccctgata aattaaatga tggtgatata tccgcattag ctggccttct ggcaaaactg 3300 tcaggaagtg ttgcgctgtg gttaattgat gagagagccg aacgctatga aaaataataa 3360 actggcgacc agtgaattaa gaagccttgc caacagcgca atatctttaa acaacgcagc 3420 aaacgaagta atgaatatgt ggcttcagtc gctggtgaat aatgaacgcg atgaatcaac 3480 tgcaagatta atattagccg tttctgaatt actggatagt tcaaccagca aaatagagag 3540 catatcagag aagattaacg gcttatcagg tcacgctatc ggggaataaa aataatgaaa 3600 cttaaatatc ctggcttaac tgacagcggc aaaactcgca ctaaattcat gcgcggggat 3660 atttaccgcg accagtacgg cggcacggta atgattaagg gcgtggagga acggcgcgta 3720 acctaccatc gtgaaggcta cgaatatgat tgcgtgatgc ctgtttatca gttccggcgt 3780 gatttttctc tggtacaggc agcgccccgc agtaaaccaa ccagcaggga gaaagcacgc 3840 gccaatattc aggaaataaa aaagatgctt aacgtattca ggggtaaaaa atgaaactgg 3900 caccgaacgt aaaaaaacag ccacgcggaa taaaacacaa agacacagag gtgattattt 3960 tcgcgggtag tgatgcgtgg gcacatgcaa aacagtggca ggagcaggac ggccccgcat 4020 ccggcgataa tgtgcctcct gtgtggcttg gggagcagca gttatcagaa ctggataagc 4080 tgcaaattgt gccggaaggc agaaaatccg tgcgcatatt cagggccgga catcttgcac 4140 cagtaatgat caaggcgatt ggtcaaaagc tggcggcggc tggtgtacag gatgcaaatt 4200 tttatcctga gggtatgcac ggtcagaagg tggagaactg gcgcgaatat ctggcccgtg 4260 agcggcagaa tctttctgat ggtctggtta ttgagtttcc ggtaaagaaa aaagataccg 4320 gaagccatag cgatgacgaa ttaaagccac gcgttgaaag tcgcgccgat ggtgttttct 4380 gggtaacgcc caaagtggat aagcagtcag gcgaaattat ccggcctgag acgtggttat 4440 gttctccgct tgaactactg ggaacgggga cgatcggtaa agagcattac cgcgtgatgc 4500 gctggaaaaa aaccgcaaac catgaagtca tcacaatggc gatcccgtgt ggtggtatcg 4560 gcgaccgtga cggctggcgg ttacttaaag atcacgggct gaacgtgaca accaacggca 4620 aatacagggc aatcctggcg gactggatgc agttaagcgg aagccatgag gaatggcagt 4680 taagcacaac aacgggctgg cattttggcg cgtacatcat gccggacggt tcgatcattg 4740 gtgaatctga aaaaccgatc ctgtttaccg gaaaaagcgc cgcgattaac ggttattccg 4800 tggcgggcac ggcggatggc tggcgcgaca agcgtggcgc ggctggctgg cggtaatgcc 4860 tcaatgatac tgggtgtggc aacgtcactg gcagcgcctt taattggcct tgtgggtgct 4920 gacggttcgg ggtgcatctt ttcgaacagt catcggcagg taagaccacc acgcagaaca 4980 tcgcatcaag tttatgggga gagccggacg cgcagcggct gacctggtac ggcacggcgt 5040 taggtattgc caatgaggcc gaggcccata atgacgggct tttaccactg gatgagatag 5100 gccaggccgg aaatcgcgcg ggaagtgtca acgtctgctt atacgctgtt taacggttca 5160 gggaaattgc agggggcgaa ggatcggcgg caacagggag atcaaacact ggcgaacggt 5220 ggcaatcagc accggagaaa tggacgttga gacattcctc aaaagtgagg ggataaaagt 5280 taaggcgggg cagcttgtcc gactgcttaa cgttccgatg gaaaaagcca cgaaatttca 5340 cgaatacagc aacggtaagg aacatgctga cgcgttaaag gatgcctgga cagcaaatca 5400 cggggcggcg ggtcgtgagt gggttaaatg gctggcaggc caccagcagg aggcaaagga 5460 cacggtaagg gaatgccgcg aacggtggcg caacctgata ccggagagtt acggcgagca 5520 ggtccaccgc gtgggtgaac gtttcgccat actggaggcc gcgcttgtgc tttccggtca 5580 tgtaactggc tgggtcgtgc aggaatgccg cgacgcgata cagcataact ttaatgcctg 5640 ggtgaaggag ttcggcacgg gtaacaggga atttaaacag atggttgaac aggctgaggc 5700 gtttttgtcg tcgtttgggt ttagccgcta ccttccgcac cccaatacag atgagcgtga 5760 tttaccgatt aaagagcttg ccggatacag aaaagggagc attcgcaacg aagatgacga 5820 gatgcgctat tacacgttcc cgcacgtgtt tgagagtgag atagcgaagg gatttaatcc 5880 ggcgcatttt gcgcgtgccc tggatgctgc cggaatgctg gagaagggaa gcgatcgccg 5940 atacaaaaaa aaggcgctgg gcaagattgg gggtaagcag catgtttttt acgtgctgat 6000 gttccagcct gatgatgaag attaatcccc tgtgtgagga aaaaaattgc gggttatgcg 6060 ggttatcctg tgtataagtg tattaagtgt atgaatataa aggaaatcaa taacccgcac 6120 gtaacccgca aaagggcatt tataacccgc aaaagcacga ttataacccg caggcgaata 6180 actgaagtaa caccggacag tcatgcgtaa cccgcagaaa aaaccccgtt tgcgggttat 6240 tttgagcgtt ttgcgggtta cgtgttgagc aaataataaa cagggtgttt tgcaacatgc 6300 tgatataaaa gggtaaaaaa tggttagcac gctaagataa cccaataacc cgcataaccc 6360 gcacatgttt ctatatatat aaattgaggt ggcaaatgac cagaacacgc agagacagaa 6420 cagagccgaa atataaagcg ttagatataa cagagctggc cttaaaggtg gcaatcagaa 6480 cgatagaccg acacgtaggg gaaggatacg cgaaggaaca tcccgacctg ataagcgcat 6540 tcatgaccac agcagcggca aactttgcca cgttgacaga acgggagatt gccgaagcgg 6600 aacaggtaac aaccatcaac gttaaaaccg gagaggtgga atcatgacag cacagatagc 6660 ggcttacggg cggctggtgg acgacccgca ggtaaaacag accagtaagg gcacaccgat 6720 gacgctggcg cgtatggcgg tatcgttgcc atgtagtcag gcgcaggatg ggcaggcgac 6780 gttatggcta tcggtcatcg catttggtaa gcaggccgac ttcctggcta aacatcaaaa 6840 aggcgacgtt gccagcgtat ccggcacgat gcaggtcagc cagtggaccg gacagaacgg 6900 ggaaacgcgg cagggttatc aggttattgc agacagcgta atcagtgccc gtgcggcacg 6960 tcctggcggg aacagacgca aaaccacagg cacacagggt aatcagccac cagcgggagg 7020 cgatgaccct tacggtgacg gtattccgtt ctgagggggt ggcgatggta catgaccgca 7080 tagcggaaga actcgaggcg aaaggctttt accggagggc ggcggcgcga tggggtgaag 7140 tcatgctgct ggtggagaca gacaaggaac ggcatcaggt tacgatgcga cggctggaat 7200 gttccaggaa ggcacagaag ccaccggagc cgccggataa cttcggagac ctgagaaagg 7260 cagtcgatcg cacttatgct gaaatgggta tagatggtgt aagcgatgaa atatggcgta 7320 attacccaga cagctaatca acagccggag aaatccggct ttttttgcac cagttgaaac 7380 ggtatggcgc attaccgggt tttcgtcacg gtcaggcata gttactatct gaaacaaaca 7440 gacacaacag aggaaaaaac aatgccgatg aaatttgatg agatattaaa acagcgtgat 7500 aaataccatg ctgacaacat ggagacgatg agcatcaatg attaccgcgc attcctggag 7560 acgggcgcac tgattgaaaa ggatcagcat ggttttgtga gatgtgctct gtccggtgaa 7620 atgctggcgg taaatcctga acagatagat gcattgatag aatttctgaa agggatcagg 7680 gactgagcac gcatacagcc ggagcaatcc ggctttttgt cattttttgt aaattatttg 7740 ttcgtggttg ttccacgttg ttcactgaca ggatcggcat attttacccg aactgaatca 7800 tgagtattct cgcccgtggt gccaggacgc tggggccact ttcccgcctg ttaatgtgct 7860 cgccaatatt cattaccagg cgggaaaacg atcggtgcga ttgctgattt ccttatgaaa 7920 aacggttgag tttttgccgc gtcctggagt tccttactta accccaggac ttttttttat 7980 gccgagaata atcgaattac gccagcagaa aaccgccatt aaaaatcaga tgcgcgacat 8040 gctggagaac gcggaaaaag aaaaccgcag ccttaacgat gcagagggcg caaaatttga 8100 cgaattacgc gctaaagctg aatccctcga taaagacatt tcccgccttg aagccattgc 8160 agacgaagag cgcagcaagc caggtaaaag cagccagacc actgacccgg cagaactccg 8220 caactacatc ctgacaggtg aaacccgcgc attaagtaca ggcgttcccg ctgatggtgg 8280 ttataccgtt atccccgaac tgaacaccga aatcatgcga atgctgacgg atgaatccac 8340 catgcgccgc atctgtaccg tgaagaaaat cagcagcaac gagtttaagc agcttgtttc 8400 cgctggcggt gcgaccgtta accacggtga agagggtaag acacgcgaac agaccagcac 8460 cccgcagatt aacgaggtga gcattaagct gtatccggtc tatgcgtacc cgcgcaccac 8520 acaggaaatc gtggattttt ccgatgtgga catcctttca tggctgacgg gtgagattgg 8580 cgacaccttc acggaaaccg aagaaagcga tctggttgtg ggcgacggtg acaaaaaagc 8640 aaaaggtttt ttatccgtac cccgtgcaga gaagaacgac aaagagcgtg attttggtac 8700 gttgcaggta attaaacctt ccgaatctct ggcgtggaca tctgcggacc cgctgatcga 8760 cctgaaattt gcattacgta aaaaataccg caaaaacgcg gtctgggtgg ttaactccac 8820 gacggcggca aaacttcaga aggtgaagaa cgcgaacggt gattacatct ggcgcgaccg 8880 tttacaggcg ggtgatcctg atacgttgct gggccttccg gtcgaatatc tggagtttat 8940 gcctgataac gttattgccc tgggtgactt caaacgcggt tactacattg ttgatcacga 9000 aacaggtgtt cgcaccagac cggacaacct cacagagccg ggtttcatca aaattttcac 9060 gcagaaatat ttaggcggtg gcgtggtgga ttcgaacgcg atcaagattc tggaactgcc 9120 acaggacgac gattaacagc atacagaagg ggcttaaaag cccctttagt gttttatggg 9180 tgaaaaaatt atgaagagta tggaaatccg gtcatcggaa atcaccacca gcgccagcaa 9240 cacgcttaca ggctacgttg ttcgctggga taacctttca gagctgctat ggggggagtt 9300 ttacgaaaaa ttccagcggg gagcgtttac tgaatggctt gcggcgggta atgacgttcg 9360 cggcctgtat gagcatgacc acagcatgtt actggggcgc acccgttccg gcacgctgaa 9420 actggaagag gacgaaacag ggttacgctt tgaactgacc ccaccggata ccagtacagg 9480 gcgcgacgtt atcgaactgg ttaagcgtgg ggacatctcg gggatgagct ttggctttcg 9540 ctcccgtaag gatgtatggg ataccacaac agatccatgc gtgcgcaccg tgctggtggc 9600 ggaactgtac gaaattaccg ttacatcggt accggcttac cccgattccg gcgtggagct 9660 ggcccgccgt tccctgtatg agcagcaccc cgaaaaaatg ccgcgtgcgg ataatcgccg 9720 ctggtgggcg gatttagcgg gggtgtgata tgtggccttt cagaagaaaa aaagagcagc 9780 gcagcatgac gcttgatgag tttatggcgc tggctggcac atcgaacacg ggggcgggtg 9840 agtacgtatc atcggggaca gcggaatcac tgcccgccgt catgaacgcc gtgacggtca 9900 tctctgaggc ggtggctacc atgccgtgtt acctgtacct ggtacgcaat gagaagggga 9960 aggaggcccg cgagtggctt gattctcatc cggtcgatca tatcctcaac gagcgcccga 1002 0 acgcgtggca gacgccctat cagtttaagc gaatgatggt ccgccactgc ctgttaaacg 1008 0 gtaatgctta tgcggtgatt cagtgggggc gtgatggttt tccggtggct ttgcaccctt 1014 0 acccgccgca gtcggtgaac gtggagcaga caggcgaaca caactggcgc tattgcatca 1020 0 ctgacgccta caccggaaac acccacaact atttaccgtg ggaagtactt caccttcgtt 1026 0 actccacgga tgacggcttt atggggcgct cacctgtaac catctgccgc gaatcgctgg 1032 0 ggcttgggct ggcccaacaa cgccacggcg cgagcgtgat gcgtgatggc atgatggcgg 1038 0 caggggttat cacgtcaggc gaatggctgg acggcgtgaa gggcaaacag gcattagccg 1044 0 cactggaacg ctacaaaggg gccagaaacg ccggaaaaac gcccatcctt gaagggggta 1050 0 tgagctatca gcagctgggc atgagtaatc aggatgctga atggctggcc tcccgtcgct 1056 0 ttaccattga agacatcgcc cgaatgttca acgtctcgcc gatttttttg caggaataca 1062 0 gcaacagcac ctacagcaat ttcagcgagg caagccgcgc atttctcacc atgacgatgc 1068 0 gcccgtggct ggcgaacttt gagcagcaga taaaaaacgc cctgctggtg gcctcgcctg 1074 0 tacctggtat ccggtatcag gtggagtttg acagcgcgga cctgttacgg gccacacctg 1080 0 gcgaacgctt tgccacctat gagcgcggca tcaaatccgg cgttatgtgc ccgaacgaag 1086 0 cccgcgaacg tgaaggactg tcaccgcgtg atggtggtga tgagttcagc caggcatgga 1092 0 aacaggaagt aaaaatcagc gagggagaaa aaccggaatg aacatagggc gactgcgtga 1098 0 caggataacg attcagaccc tgaaacagac cagagccatg acgggcgaaa tactcgaaac 1104 0 gtgggaggac ggtcacacac tctgggcaag cgtgaacatg atcagcagca aggaggccat 1110 0 ttcatcgggc gcagagctgg cgattggtac cgtaaggatc tggatacggt accggaagga 1116 0 catcaacgcc accagccgga taaaggtcag tacggggccg ctggcggggc gtgtactgaa 1122 0 tatcatcggg cagccgttgc cggatgtcgc caggacacgc cttgaaattc tttgtcgtga 1128 0 gggcgcggaa aaatgacaga agaacttatc accctggaag aagtgaaact ccattgccgc 1134 0 atcgatggcg acgaggaaga ccagttaatc agcggataca ttgccgcatc gcttgaggcg 1140 0 tgccagatac acataggcag gcgctttgat gacgggctgg agttcacgcc agccataaag 1146 0 attggctgca tgatgtttat cgctcacctg tatgaaaatc gccagattgt cgcggataac 1152 0 gcaaaaacac gcgtacccat gacgattggt gcactctgga cggcttaccg tgatgtgggg 1158 0 gtgtactgat gccgtggcaa ccattaagac gatgcacaga accaggctgt aacaggcgcg 1164 0 tgaagtccgg caagtgtgag gagcacaggc gggcggcatg gcgtgcagag gatgccagac 1170 0 gaggacaccg ccgcgcgcgt gggtactcca gacagtggga caaataccgc gccatgtatc 1176 0 tgagtaaaaa cccgttatgc gtgcgatgcc ttgagaaggg gatatatacg cccgccgtgg 1182 0 tggtggatca cattatcccc atcgatggcg gtgatgatgt tctcttctgg cccgaatgga 1188 0 accatcaacc attgtgtcag gcgtgccata accagaaaac gaaatggctt gatccggcaa 1194 0 caaaaagcaa gcgtgccgca ggtggatttc gtgaagagga agaacgggcc gctaaccgca 1200 0 ataactggat gtatgacgct gatgaatgag cgggaacaaa accgccttat ccgtggactt 1206 0 ataaggcagc gtgacgcatg gaagacacag gaaacagggc ataaagataa agcgtcagga 1212 0 cgcgcagaac gcatcacagc gaagcgatta accgaccgtg accgcgaggt tatggaatgt 1218 0 ttccgcaatc gctgatgagg ctgtatgacg gggtgggggg cgttttcagg acaaacccga 1224 0 ccccgccggg caccgaacgc ctcctcaaat ttttatgcac gggaattttt tgaaaaataa 1230 0 tctggcgaaa aaataagcat ggcaagacca ccgaaagccc ccgcctacct ggatgatatc 1236 0 gccgtgaagc agtggcggga aaaatcgcgg cagcttgcgg aacggggtga cctgactccc 1242 0 gccgactgga gtaatctgga actgtattgc gtcaattact cgatataccg gaaagccgtc 1248 0 gcagaccttg cggcgcgcgg gttcagcatt gttaacagtc agggcggaga gagcagaaac 1254 0 cccgcattaa gcgcgaaatc cgacgcggaa agagtgatga taaaaatggc ctccttgctc 1260 0 ggttttgacc cgataagccg ccgtaaaaat ccaccggaaa cagaagaaga ggacgagctt 1266 0 gaccgcctgg aataagtacg cagaagacgt aaaaacgggc aaaattccgg cctgtaaacg 1272 0 gttaaaacag gctgttaaac ggtacttttc ggaccttaaa agcccccttt acacgttcga 1278 0 tcgtgaggtt gtggagcggt ttattgcctt ttccagggtg tgcccgcacg taaaaggacc 1284 0 gatgcgtggc agacccattg agctggagcc gtggcagcag ttcgcctttg cgtgcatcct 1290 0 cggctttaag gttaaggcca ccggacggcg caaatacacg agcgccttta tcgaagtgcc 1296 0 gcgcaaaaat gcgaaatcca cgaccgccgc gattctggct aactggtttt tgattatgga 1302 0 gaacggtcag caggatatct acaccgcagc ggtgagccgt gaccaggcgc ggatcgtctt 1308 0 tgatgatgcg cgtcagatgt gccttttatc ccgaccgtta cgcaggcggg tgaatattca 1314 0 ggcgcataag gtgatacacc cgaaaagcaa cagcctgtta aagccgctgg cagcaaaagc 1320 0 ggcaaccatt gaaggtacaa ccccgagtct tgccattgtg gatgaatatc acctgcaccc 1326 0 tgacaacggg gtttattccg cgcttgaact gggaatgggg gcgcgtccgg aggggctgtt 1332 0 atttgccatc accacatcgg ggagcaacgt tgtttcagcc tgtaaacaac actacgacta 1338 0 ttgctgccag atactggatg gtgaagaggt gaacgaatcc atgttcgtgc tgatttacga 1344 0 gctggatgat gaaagcgagg ttgacgatcc ggcgatgtgg ataaaggcga atcccaatat 1350 0 cgatgtttcc gtcgatcgtg aaaaactggc ctcaaccatc cagaaagcgc ggggaatacc 1356 0 gtcgcagtgg gtggagatga tgacaaagcg atttaatatc tggtgccagg gggctacccc 1362 0 gtggatgggt aacggcgcat gggctgagtg tgccggaacg ttcacggagg aagatttaca 1368 0 cggccaggag tgttacgcgg ggctggattt atcatcaacc agcgatattt ccagcgtatg 1374 0 ctatgccttt ccggtcggta aaaccattat gctgatttcc cgtcattatc tgccggagtt 1380 0 ccagctacag aaccccgcca ataaaaaccg cgctgtctat cgtcagtggg ctaaagcggg 1386 0 ctggatacgc acaacgcctg gcgactgcat tgattacgac cggatcagag atgacatcat 1392 0 gcaggacgcg gagaaatttc atatcaggct ggtgggcttt gatacgtgga acgccacgca 1398 0 tctcagaacg caattacagg gggcaggttt tgaggtggag ccgttcccgc aaacctacct 1404 0 cagattcagt ccggcggcga aatcgttcga agtttttgtt aaccgcaggg tgattgtgca 1410 0 tcgtggcgat ccggtgttgt cctggtcgat gagtaacgtc gtgatgcaga gtgacgcgaa 1416 0 cgccaatatc aagccgaaca agaaaaaatc accgaacaag atagacccga gcgtggcggc 1422 0 actgatggcg tttggtacat tccaggcaga gcatgaggat tttgcttttg atataagcga 1428 0 cagccaccgc cagaaactgg aagaattcag cggggtgtaa tgaggtcagc agcatgacag 1434 0 aagccgaact actgggatta atccgccgcg tatctggaat cagccagcag gctgacgaac 1440 0 agaccacgca gccggacagc gtgacagccg aaaattatgc gcgtgttgtt gctgaggtga 1446 0 tgtgccgtga tggtatccag cttaatgatg ttgatatgcg caacatacgg atccgcgttc 1452 0 ttgaaatgct ggcctacaat cgccgcgttg aactgcatcg ggagaaagaa aaaataacgt 1458 0 accactggaa gaagccggag cggttgcggc ggtaactggt tgatattttc gaaattcgcc 1464 0 agcggcgaac atcggggaaa ccagcctaac ccgttgattc tttcggaaac agccattggc 1470 0 ggaatccggc gcggtaactt gctgatattc ccgataacgc aaaattgcgt ggctgaatga 1476 0 acattatgat tacttatgat tacgcagatg attaaggcct aaaccgttga ttcttcccaa 1482 0 tttccacaga ctgtggaagt tggcgcggta acttactgag attaaagcaa agcgcaaaat 1488 0 tgcgccgact acatccctca catgcgaaat tttcgcagtt taattactcg ccagtttgat 1494 0 cgttaacccg ctgatatttt cgggaacctc aatttgagga agtcggcgcg gtaactggtt 1500 0 gatactttcg acctcctcaa tttgaggagg tcggggcaca gaaaaacaac gaatatgttg 1506 0 tttttgggaa tggtcataat gaccacgcag accatcaagg caaccacaac gaacatcgtt 1512 0 acggttggag cttttacccc actgggggaa aggtattacg ataatcataa cacctaccga 1518 0 acaggtaaaa cccaccagcc tgattaacag ttaaccggaa aaaaaatccg gtagccccgt 1524 0 tatggggatc cccatatcga cattaacgcc cctcatgaat tggtgcgctt ccccctggaa 1530 0 agattacccg cctgtatatt tcttgtgtct atttgttcca cgttgtttca tacagtgcac 1536 0 cgaacggtgt agttaatggt gtagtcaatt tgctgttttt agcacttttt gcagtgtggg 1542 0 ttgtttaatt aaatcaatgg gttgccttgc tgtggtgata aaa 1546 3 <210> 1213 <211> 410 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(182..1411) <400> 1213 Met Ser Arg Ala Leu Asn Lys Leu Ser Asp Thr Gln Leu Arg Lys Ile 1 5 10 15 Asn Gly Thr Pro Ala Gln Lys Thr Ala Phe Leu Asn Asp Gly Gly Asn 20 25 30 Leu Ser Val Arg His Ser Thr Ser Gly Leu Leu Thr Trp Tyr Phe Thr 35 40 45 Tyr Arg Ala Gly Thr Gly Arg Gly Ala Pro Pro Glu Arg Ile Lys Leu 50 55 60 Gly Asn Tyr Pro Asp Leu Ser Leu Lys Ser Ala Arg Glu Lys Ala Ala 65 70 75 80 Gln Cys Arg Ala Trp Leu Ala Glu Gly Lys Asn Pro Arg His Glu Leu 85 90 95 Asn Tyr Thr Val Gln Glu Ala Leu Lys Pro Val Thr Val Gly Asp Ala 100 105 110 Leu Thr Tyr Trp Leu Glu Ser Tyr Ala Lys Glu Asn Arg Val Asp Tyr 115 120 125 Ala Ala Leu Lys Lys Arg Leu Asn Asn His Val Ile Gln His Ile Gly 130 135 140 Ala Met Pro Leu Asp Lys Cys Glu Leu Arg His Trp Leu Ala Cys Phe 145 150 155 160 Asp Gln Val Ala Lys Arg Thr Pro Val Thr Ala Gly Phe Leu Leu Gln 165 170 175 Thr Cys Lys Gln Ala Leu Lys Phe Cys Arg Arg Arg Arg Tyr Ala Ile 180 185 190 Ser Asn Val Leu Asp Asp Met Ser Val Ala Asp Val Gly Lys Lys Pro 195 200 205 Asp Ile Ser Glu Arg Val Leu Ser Thr Lys Glu Leu Gly Glu Leu Leu 210 215 220 Gln Ala Leu Asp Lys Lys Ile Phe Ser Pro Tyr Tyr Ile Ala Leu Ile 225 230 235 240 Arg Leu Leu Ile Val Phe Gly Cys Arg Thr Val Glu Leu Arg Leu Ser 245 250 255 Glu Ile Ser Glu Trp Asp Phe Thr Glu Met Leu Trp Thr Val Pro Lys 260 265 270 Glu His Ser Lys Thr Lys Val Ala Ile Phe Arg Pro Ile Pro Glu Ala 275 280 285 Ile Leu Pro Phe Val Thr Gln Leu Val Glu Gln Asn Arg His Thr Gly 290 295 300 Leu Leu Leu Gly Glu Val Lys Gln Glu Thr Ser Val Ser Gln Tyr Gly 305 310 315 320 Arg Leu Ala His Arg Arg Leu Asn His Pro His Trp Ser Leu His Asp 325 330 335 Ile Arg Arg Thr Phe Thr Thr Met Leu Asn Asp Leu Gly Val Asp Pro 340 345 350 His Val Val Glu Gln Leu Thr Gly His Gln Met Pro Gly Met Gln Arg 355 360 365 Val Tyr Asn His Ser Arg Tyr Leu Asp Ala Lys Arg Asn Ala Leu Asp 370 375 380 Met Trp Thr Glu Arg Leu Gly Ile Leu Ala Gly Thr His Glu Asn Val 385 390 395 400 Thr Thr Leu Pro Val Ala Arg Arg Lys * 405 <210> 1214 <211> 63 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1776..1964) <400> 1214 Val Leu Ser Thr Asp Arg Phe Ile Arg Glu Lys Glu Cys Glu Lys Leu 1 5 10 15 Thr Gly Leu Ser Arg Thr Cys Arg Tyr Arg Leu Glu Lys Ala Gly Gln 20 25 30 Phe Pro Ser Arg Arg Lys Leu Gly Gly Arg Ser Val Gly Trp Ser Leu 35 40 45 Ser Glu Val Leu Ala Trp Lys Asp Ser Cys Lys Ala Val His * 50 55 60 <210> 1215 <211> 248 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2022..2765) <400> 1215 Met Lys Ile Glu Tyr Thr Pro Glu Arg Gly Arg Gly Phe Val Arg Pro 1 5 10 15 Gly Glu Thr Glu Lys Gln Gln Asn Trp Gly Phe Ser Gly Ile Lys Lys 20 25 30 Ala Ala Pro Lys Trp Ser Arg Leu Ser Glu Gln Ile Thr Arg Cys Ala 35 40 45 Val Cys Val Cys Asp Pro Lys His Lys His Gly Asp Asp Ser Arg Tyr 50 55 60 Gln Ala Gly Gly Gln Cys Asn Gln Ser Gly Ser Val Arg Cys His Thr 65 70 75 80 Cys Asn Glu Arg Phe Ser Leu Tyr Ser Leu Arg Asn Cys Ser Arg Ala 85 90 95 Lys Ala His Gly Ala Asn Leu Ser Asp Ser Cys Ser Ile Phe Leu Arg 100 105 110 Arg Leu Phe Arg Ala Gly Asp Asn Val Leu Val Asn Ser Leu Ser Val 115 120 125 Ile Val Leu Ser Cys Ile Ala Met Arg Arg Asn Thr Ser His His Gly 130 135 140 Ala Asp Ser Phe Tyr Pro Leu Gly Ser Ile Pro Arg Arg Phe Ser Ser 145 150 155 160 Val Arg Pro Asn Ser Leu Ser Gln Leu Ala Arg Leu Met Pro Ser Leu 165 170 175 Cys Ala Ser Leu Ser Asn Cys Ser Phe Ser Ser Gly Glu Ile Arg Ile 180 185 190 Leu Asn Cys Gly Asp Cys Pro Ser Pro Leu Gly Leu Leu Ser Arg Leu 195 200 205 Ile Val Asp Lys Trp Ser Pro Ile Glu Leu Ala Phe Leu Leu Leu Gly 210 215 220 Gly His Leu Asn Thr Arg Ala Leu Lys Lys Ala Lys Pro Arg Lys Cys 225 230 235 240 His Tyr His Ser Gln Gly Phe * 245 <210> 1216 <211> 66 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2791..2988) <400> 1216 Met Val Ala Val Asn His Ile Pro His Leu Val His Thr Gln Thr Ala 1 5 10 15 Phe Val Trp Arg Phe Leu Ala Leu Ser Ala Gly Glu Ser Gln Ile Ile 20 25 30 His Val Thr Ala Trp Thr Glu Arg Glu Ala Arg Ser Arg Cys Pro Ser 35 40 45 Gly Cys Val Ala Val Phe Ala Ala Arg Ile Arg Gln Gly Val Cys His 50 55 60 Ala * 65 <210> 1217 <211> 62 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2981..3166) <400> 1217 Met Leu Lys Thr Phe Arg Val Phe Ala Ser Ala Val Asn Pro Leu Gly 1 5 10 15 His Thr Ile Gly Ile Ala Gln Asn Val Lys Ala Val Asn Val Gln Thr 20 25 30 Ala Ile Ala Ala Val Arg Ser Glu Ser Ser Glu Tyr Gly Leu Ser Gln 35 40 45 Val Ile Ile Ser Ala Val Tyr Glu Leu Lys Glu Val His * 50 55 60 <210> 1218 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3166..3357) <400> 1218 Met Lys Glu Ile Thr Leu His Glu Ala Ala Glu Arg Ala His Gln Thr 1 5 10 15 Glu Ile Ile Cys Arg Leu Leu Glu Val Tyr Pro Asp Lys Leu Asn Asp 20 25 30 Gly Asp Ile Ser Ala Leu Ala Gly Leu Leu Ala Lys Leu Ser Gly Ser 35 40 45 Val Ala Leu Trp Leu Ile Asp Glu Arg Ala Glu Arg Tyr Glu Lys * 50 55 60 <210> 1219 <211> 81 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3347..3589) <400> 1219 Met Lys Asn Asn Lys Leu Ala Thr Ser Glu Leu Arg Ser Leu Ala Asn 1 5 10 15 Ser Ala Ile Ser Leu Asn Asn Ala Ala Asn Glu Val Met Asn Met Trp 20 25 30 Leu Gln Ser Leu Val Asn Asn Glu Arg Asp Glu Ser Thr Ala Arg Leu 35 40 45 Ile Leu Ala Val Ser Glu Leu Leu Asp Ser Ser Thr Ser Lys Ile Glu 50 55 60 Ser Ile Ser Glu Lys Ile Asn Gly Leu Ser Gly His Ala Ile Gly Glu 65 70 75 80 * <210> 1220 <211> 100 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3595..3894) <400> 1220 Met Lys Leu Lys Tyr Pro Gly Leu Thr Asp Ser Gly Lys Thr Arg Thr 1 5 10 15 Lys Phe Met Arg Gly Asp Ile Tyr Arg Asp Gln Tyr Gly Gly Thr Val 20 25 30 Met Ile Lys Gly Val Glu Glu Arg Arg Val Thr Tyr His Arg Glu Gly 35 40 45 Tyr Glu Tyr Asp Cys Val Met Pro Val Tyr Gln Phe Arg Arg Asp Phe 50 55 60 Ser Leu Val Gln Ala Ala Pro Arg Ser Lys Pro Thr Ser Arg Glu Lys 65 70 75 80 Ala Arg Ala Asn Ile Gln Glu Ile Lys Lys Met Leu Asn Val Phe Arg 85 90 95 Gly Lys Lys * <210> 1221 <211> 322 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3891..4856) <400> 1221 Met Lys Leu Ala Pro Asn Val Lys Lys Gln Pro Arg Gly Ile Lys His 1 5 10 15 Lys Asp Thr Glu Val Ile Ile Phe Ala Gly Ser Asp Ala Trp Ala His 20 25 30 Ala Lys Gln Trp Gln Glu Gln Asp Gly Pro Ala Ser Gly Asp Asn Val 35 40 45 Pro Pro Val Trp Leu Gly Glu Gln Gln Leu Ser Glu Leu Asp Lys Leu 50 55 60 Gln Ile Val Pro Glu Gly Arg Lys Ser Val Arg Ile Phe Arg Ala Gly 65 70 75 80 His Leu Ala Pro Val Met Ile Lys Ala Ile Gly Gln Lys Leu Ala Ala 85 90 95 Ala Gly Val Gln Asp Ala Asn Phe Tyr Pro Glu Gly Met His Gly Gln 100 105 110 Lys Val Glu Asn Trp Arg Glu Tyr Leu Ala Arg Glu Arg Gln Asn Leu 115 120 125 Ser Asp Gly Leu Val Ile Glu Phe Pro Val Lys Lys Lys Asp Thr Gly 130 135 140 Ser His Ser Asp Asp Glu Leu Lys Pro Arg Val Glu Ser Arg Ala Asp 145 150 155 160 Gly Val Phe Trp Val Thr Pro Lys Val Asp Lys Gln Ser Gly Glu Ile 165 170 175 Ile Arg Pro Glu Thr Trp Leu Cys Ser Pro Leu Glu Leu Leu Gly Thr 180 185 190 Gly Thr Ile Gly Lys Glu His Tyr Arg Val Met Arg Trp Lys Lys Thr 195 200 205 Ala Asn His Glu Val Ile Thr Met Ala Ile Pro Cys Gly Gly Ile Gly 210 215 220 Asp Arg Asp Gly Trp Arg Leu Leu Lys Asp His Gly Leu Asn Val Thr 225 230 235 240 Thr Asn Gly Lys Tyr Arg Ala Ile Leu Ala Asp Trp Met Gln Leu Ser 245 250 255 Gly Ser His Glu Glu Trp Gln Leu Ser Thr Thr Thr Gly Trp His Phe 260 265 270 Gly Ala Tyr Ile Met Pro Asp Gly Ser Ile Ile Gly Glu Ser Glu Lys 275 280 285 Pro Ile Leu Phe Thr Gly Lys Ser Ala Ala Ile Asn Gly Tyr Ser Val 290 295 300 Ala Gly Thr Ala Asp Gly Trp Arg Asp Lys Arg Gly Ala Ala Gly Trp 305 310 315 320 Arg * <210> 1222 <211> 74 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4932..5153) <400> 1222 Val His Leu Phe Glu Gln Ser Ser Ala Gly Lys Thr Thr Thr Gln Asn 1 5 10 15 Ile Ala Ser Ser Leu Trp Gly Glu Pro Asp Ala Gln Arg Leu Thr Trp 20 25 30 Tyr Gly Thr Ala Leu Gly Ile Ala Asn Glu Ala Glu Ala His Asn Asp 35 40 45 Gly Leu Leu Pro Leu Asp Glu Ile Gly Gln Ala Gly Asn Arg Ala Gly 50 55 60 Ser Val Asn Val Cys Leu Tyr Ala Val * 65 70 <210> 1223 <211> 269 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5219..6025) <400> 1223 Val Ala Ile Ser Thr Gly Glu Met Asp Val Glu Thr Phe Leu Lys Ser 1 5 10 15 Glu Gly Ile Lys Val Lys Ala Gly Gln Leu Val Arg Leu Leu Asn Val 20 25 30 Pro Met Glu Lys Ala Thr Lys Phe His Glu Tyr Ser Asn Gly Lys Glu 35 40 45 His Ala Asp Ala Leu Lys Asp Ala Trp Thr Ala Asn His Gly Ala Ala 50 55 60 Gly Arg Glu Trp Val Lys Trp Leu Ala Gly His Gln Gln Glu Ala Lys 65 70 75 80 Asp Thr Val Arg Glu Cys Arg Glu Arg Trp Arg Asn Leu Ile Pro Glu 85 90 95 Ser Tyr Gly Glu Gln Val His Arg Val Gly Glu Arg Phe Ala Ile Leu 100 105 110 Glu Ala Ala Leu Val Leu Ser Gly His Val Thr Gly Trp Val Val Gln 115 120 125 Glu Cys Arg Asp Ala Ile Gln His Asn Phe Asn Ala Trp Val Lys Glu 130 135 140 Phe Gly Thr Gly Asn Arg Glu Phe Lys Gln Met Val Glu Gln Ala Glu 145 150 155 160 Ala Phe Leu Ser Ser Phe Gly Phe Ser Arg Tyr Leu Pro His Pro Asn 165 170 175 Thr Asp Glu Arg Asp Leu Pro Ile Lys Glu Leu Ala Gly Tyr Arg Lys 180 185 190 Gly Ser Ile Arg Asn Glu Asp Asp Glu Met Arg Tyr Tyr Thr Phe Pro 195 200 205 His Val Phe Glu Ser Glu Ile Ala Lys Gly Phe Asn Pro Ala His Phe 210 215 220 Ala Arg Ala Leu Asp Ala Ala Gly Met Leu Glu Lys Gly Ser Asp Arg 225 230 235 240 Arg Tyr Lys Lys Lys Ala Leu Gly Lys Ile Gly Gly Lys Gln His Val 245 250 255 Phe Tyr Val Leu Met Phe Gln Pro Asp Asp Glu Asp * 260 265 <210> 1224 <211> 115 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6022..6366) <400> 1224 Met Cys Gly Leu Cys Gly Leu Leu Gly Tyr Leu Ser Val Leu Thr Ile 1 5 10 15 Phe Tyr Pro Phe Ile Ser Ala Cys Cys Lys Thr Pro Cys Leu Leu Phe 20 25 30 Ala Gln His Val Thr Arg Lys Thr Leu Lys Ile Thr Arg Lys Arg Gly 35 40 45 Phe Phe Cys Gly Leu Arg Met Thr Val Arg Cys Tyr Phe Ser Tyr Ser 50 55 60 Pro Ala Gly Tyr Asn Arg Ala Phe Ala Gly Tyr Lys Cys Pro Phe Ala 65 70 75 80 Gly Tyr Val Arg Val Ile Asp Phe Leu Tyr Ile His Thr Leu Asn Thr 85 90 95 Leu Ile His Arg Ile Thr Arg Ile Thr Arg Asn Phe Phe Pro His Thr 100 105 110 Gly Asp * <210> 1225 <211> 84 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6396..6647) <400> 1225 Met Thr Arg Thr Arg Arg Asp Arg Thr Glu Pro Lys Tyr Lys Ala Leu 1 5 10 15 Asp Ile Thr Glu Leu Ala Leu Lys Val Ala Ile Arg Thr Ile Asp Arg 20 25 30 His Val Gly Glu Gly Tyr Ala Lys Glu His Pro Asp Leu Ile Ser Ala 35 40 45 Phe Met Thr Thr Ala Ala Ala Asn Phe Ala Thr Leu Thr Glu Arg Glu 50 55 60 Ile Ala Glu Ala Glu Gln Val Thr Thr Ile Asn Val Lys Thr Gly Glu 65 70 75 80 Val Glu Ser * <210> 1226 <211> 137 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6644..7054) <400> 1226 Met Thr Ala Gln Ile Ala Ala Tyr Gly Arg Leu Val Asp Asp Pro Gln 1 5 10 15 Val Lys Gln Thr Ser Lys Gly Thr Pro Met Thr Leu Ala Arg Met Ala 20 25 30 Val Ser Leu Pro Cys Ser Gln Ala Gln Asp Gly Gln Ala Thr Leu Trp 35 40 45 Leu Ser Val Ile Ala Phe Gly Lys Gln Ala Asp Phe Leu Ala Lys His 50 55 60 Gln Lys Gly Asp Val Ala Ser Val Ser Gly Thr Met Gln Val Ser Gln 65 70 75 80 Trp Thr Gly Gln Asn Gly Glu Thr Arg Gln Gly Tyr Gln Val Ile Ala 85 90 95 Asp Ser Val Ile Ser Ala Arg Ala Ala Arg Pro Gly Gly Asn Arg Arg 100 105 110 Lys Thr Thr Gly Thr Gln Gly Asn Gln Pro Pro Ala Gly Gly Asp Asp 115 120 125 Pro Tyr Gly Asp Gly Ile Pro Phe * 130 135 <210> 1227 <211> 91 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7065..7337) <400> 1227 Met Val His Asp Arg Ile Ala Glu Glu Leu Glu Ala Lys Gly Phe Tyr 1 5 10 15 Arg Arg Ala Ala Ala Arg Trp Gly Glu Val Met Leu Leu Val Glu Thr 20 25 30 Asp Lys Glu Arg His Gln Val Thr Met Arg Arg Leu Glu Cys Ser Arg 35 40 45 Lys Ala Gln Lys Pro Pro Glu Pro Pro Asp Asn Phe Gly Asp Leu Arg 50 55 60 Lys Ala Val Asp Arg Thr Tyr Ala Glu Met Gly Ile Asp Gly Val Ser 65 70 75 80 Asp Glu Ile Trp Arg Asn Tyr Pro Asp Ser * 85 90 <210> 1228 <211> 75 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7462..7686) <400> 1228 Met Pro Met Lys Phe Asp Glu Ile Leu Lys Gln Arg Asp Lys Tyr His 1 5 10 15 Ala Asp Asn Met Glu Thr Met Ser Ile Asn Asp Tyr Arg Ala Phe Leu 20 25 30 Glu Thr Gly Ala Leu Ile Glu Lys Asp Gln His Gly Phe Val Arg Cys 35 40 45 Ala Leu Ser Gly Glu Met Leu Ala Val Asn Pro Glu Gln Ile Asp Ala 50 55 60 Leu Ile Glu Phe Leu Lys Gly Ile Arg Asp * 65 70 <210> 1229 <211> 386 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7979..9136) <400> 1229 Met Pro Arg Ile Ile Glu Leu Arg Gln Gln Lys Thr Ala Ile Lys Asn 1 5 10 15 Gln Met Arg Asp Met Leu Glu Asn Ala Glu Lys Glu Asn Arg Ser Leu 20 25 30 Asn Asp Ala Glu Gly Ala Lys Phe Asp Glu Leu Arg Ala Lys Ala Glu 35 40 45 Ser Leu Asp Lys Asp Ile Ser Arg Leu Glu Ala Ile Ala Asp Glu Glu 50 55 60 Arg Ser Lys Pro Gly Lys Ser Ser Gln Thr Thr Asp Pro Ala Glu Leu 65 70 75 80 Arg Asn Tyr Ile Leu Thr Gly Glu Thr Arg Ala Leu Ser Thr Gly Val 85 90 95 Pro Ala Asp Gly Gly Tyr Thr Val Ile Pro Glu Leu Asn Thr Glu Ile 100 105 110 Met Arg Met Leu Thr Asp Glu Ser Thr Met Arg Arg Ile Cys Thr Val 115 120 125 Lys Lys Ile Ser Ser Asn Glu Phe Lys Gln Leu Val Ser Ala Gly Gly 130 135 140 Ala Thr Val Asn His Gly Glu Glu Gly Lys Thr Arg Glu Gln Thr Ser 145 150 155 160 Thr Pro Gln Ile Asn Glu Val Ser Ile Lys Leu Tyr Pro Val Tyr Ala 165 170 175 Tyr Pro Arg Thr Thr Gln Glu Ile Val Asp Phe Ser Asp Val Asp Ile 180 185 190 Leu Ser Trp Leu Thr Gly Glu Ile Gly Asp Thr Phe Thr Glu Thr Glu 195 200 205 Glu Ser Asp Leu Val Val Gly Asp Gly Asp Lys Lys Ala Lys Gly Phe 210 215 220 Leu Ser Val Pro Arg Ala Glu Lys Asn Asp Lys Glu Arg Asp Phe Gly 225 230 235 240 Thr Leu Gln Val Ile Lys Pro Ser Glu Ser Leu Ala Trp Thr Ser Ala 245 250 255 Asp Pro Leu Ile Asp Leu Lys Phe Ala Leu Arg Lys Lys Tyr Arg Lys 260 265 270 Asn Ala Val Trp Val Val Asn Ser Thr Thr Ala Ala Lys Leu Gln Lys 275 280 285 Val Lys Asn Ala Asn Gly Asp Tyr Ile Trp Arg Asp Arg Leu Gln Ala 290 295 300 Gly Asp Pro Asp Thr Leu Leu Gly Leu Pro Val Glu Tyr Leu Glu Phe 305 310 315 320 Met Pro Asp Asn Val Ile Ala Leu Gly Asp Phe Lys Arg Gly Tyr Tyr 325 330 335 Ile Val Asp His Glu Thr Gly Val Arg Thr Arg Pro Asp Asn Leu Thr 340 345 350 Glu Pro Gly Phe Ile Lys Ile Phe Thr Gln Lys Tyr Leu Gly Gly Gly 355 360 365 Val Val Asp Ser Asn Ala Ile Lys Ile Leu Glu Leu Pro Gln Asp Asp 370 375 380 Asp * 385 <210> 1230 <211> 186 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9191..9748) <400> 1230 Met Lys Ser Met Glu Ile Arg Ser Ser Glu Ile Thr Thr Ser Ala Ser 1 5 10 15 Asn Thr Leu Thr Gly Tyr Val Val Arg Trp Asp Asn Leu Ser Glu Leu 20 25 30 Leu Trp Gly Glu Phe Tyr Glu Lys Phe Gln Arg Gly Ala Phe Thr Glu 35 40 45 Trp Leu Ala Ala Gly Asn Asp Val Arg Gly Leu Tyr Glu His Asp His 50 55 60 Ser Met Leu Leu Gly Arg Thr Arg Ser Gly Thr Leu Lys Leu Glu Glu 65 70 75 80 Asp Glu Thr Gly Leu Arg Phe Glu Leu Thr Pro Pro Asp Thr Ser Thr 85 90 95 Gly Arg Asp Val Ile Glu Leu Val Lys Arg Gly Asp Ile Ser Gly Met 100 105 110 Ser Phe Gly Phe Arg Ser Arg Lys Asp Val Trp Asp Thr Thr Thr Asp 115 120 125 Pro Cys Val Arg Thr Val Leu Val Ala Glu Leu Tyr Glu Ile Thr Val 130 135 140 Thr Ser Val Pro Ala Tyr Pro Asp Ser Gly Val Glu Leu Ala Arg Arg 145 150 155 160 Ser Leu Tyr Glu Gln His Pro Glu Lys Met Pro Arg Ala Asp Asn Arg 165 170 175 Arg Trp Trp Ala Asp Leu Ala Gly Val * 180 185 <210> 1231 <211> 404 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9750..10961) <400> 1231 Met Trp Pro Phe Arg Arg Lys Lys Glu Gln Arg Ser Met Thr Leu Asp 1 5 10 15 Glu Phe Met Ala Leu Ala Gly Thr Ser Asn Thr Gly Ala Gly Glu Tyr 20 25 30 Val Ser Ser Gly Thr Ala Glu Ser Leu Pro Ala Val Met Asn Ala Val 35 40 45 Thr Val Ile Ser Glu Ala Val Ala Thr Met Pro Cys Tyr Leu Tyr Leu 50 55 60 Val Arg Asn Glu Lys Gly Lys Glu Ala Arg Glu Trp Leu Asp Ser His 65 70 75 80 Pro Val Asp His Ile Leu Asn Glu Arg Pro Asn Ala Trp Gln Thr Pro 85 90 95 Tyr Gln Phe Lys Arg Met Met Val Arg His Cys Leu Leu Asn Gly Asn 100 105 110 Ala Tyr Ala Val Ile Gln Trp Gly Arg Asp Gly Phe Pro Val Ala Leu 115 120 125 His Pro Tyr Pro Pro Gln Ser Val Asn Val Glu Gln Thr Gly Glu His 130 135 140 Asn Trp Arg Tyr Cys Ile Thr Asp Ala Tyr Thr Gly Asn Thr His Asn 145 150 155 160 Tyr Leu Pro Trp Glu Val Leu His Leu Arg Tyr Ser Thr Asp Asp Gly 165 170 175 Phe Met Gly Arg Ser Pro Val Thr Ile Cys Arg Glu Ser Leu Gly Leu 180 185 190 Gly Leu Ala Gln Gln Arg His Gly Ala Ser Val Met Arg Asp Gly Met 195 200 205 Met Ala Ala Gly Val Ile Thr Ser Gly Glu Trp Leu Asp Gly Val Lys 210 215 220 Gly Lys Gln Ala Leu Ala Ala Leu Glu Arg Tyr Lys Gly Ala Arg Asn 225 230 235 240 Ala Gly Lys Thr Pro Ile Leu Glu Gly Gly Met Ser Tyr Gln Gln Leu 245 250 255 Gly Met Ser Asn Gln Asp Ala Glu Trp Leu Ala Ser Arg Arg Phe Thr 260 265 270 Ile Glu Asp Ile Ala Arg Met Phe Asn Val Ser Pro Ile Phe Leu Gln 275 280 285 Glu Tyr Ser Asn Ser Thr Tyr Ser Asn Phe Ser Glu Ala Ser Arg Ala 290 295 300 Phe Leu Thr Met Thr Met Arg Pro Trp Leu Ala Asn Phe Glu Gln Gln 305 310 315 320 Ile Lys Asn Ala Leu Leu Val Ala Ser Pro Val Pro Gly Ile Arg Tyr 325 330 335 Gln Val Glu Phe Asp Ser Ala Asp Leu Leu Arg Ala Thr Pro Gly Glu 340 345 350 Arg Phe Ala Thr Tyr Glu Arg Gly Ile Lys Ser Gly Val Met Cys Pro 355 360 365 Asn Glu Ala Arg Glu Arg Glu Gly Leu Ser Pro Arg Asp Gly Gly Asp 370 375 380 Glu Phe Ser Gln Ala Trp Lys Gln Glu Val Lys Ile Ser Glu Gly Glu 385 390 395 400 Lys Pro Glu * <210> 1232 <211> 113 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10958..11296) <400> 1232 Met Asn Ile Gly Arg Leu Arg Asp Arg Ile Thr Ile Gln Thr Leu Lys 1 5 10 15 Gln Thr Arg Ala Met Thr Gly Glu Ile Leu Glu Thr Trp Glu Asp Gly 20 25 30 His Thr Leu Trp Ala Ser Val Asn Met Ile Ser Ser Lys Glu Ala Ile 35 40 45 Ser Ser Gly Ala Glu Leu Ala Ile Gly Thr Val Arg Ile Trp Ile Arg 50 55 60 Tyr Arg Lys Asp Ile Asn Ala Thr Ser Arg Ile Lys Val Ser Thr Gly 65 70 75 80 Pro Leu Ala Gly Arg Val Leu Asn Ile Ile Gly Gln Pro Leu Pro Asp 85 90 95 Val Ala Arg Thr Arg Leu Glu Ile Leu Cys Arg Glu Gly Ala Glu Lys 100 105 110 * <210> 1233 <211> 99 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11293..11589) <400> 1233 Met Thr Glu Glu Leu Ile Thr Leu Glu Glu Val Lys Leu His Cys Arg 1 5 10 15 Ile Asp Gly Asp Glu Glu Asp Gln Leu Ile Ser Gly Tyr Ile Ala Ala 20 25 30 Ser Leu Glu Ala Cys Gln Ile His Ile Gly Arg Arg Phe Asp Asp Gly 35 40 45 Leu Glu Phe Thr Pro Ala Ile Lys Ile Gly Cys Met Met Phe Ile Ala 50 55 60 His Leu Tyr Glu Asn Arg Gln Ile Val Ala Asp Asn Ala Lys Thr Arg 65 70 75 80 Val Pro Met Thr Ile Gly Ala Leu Trp Thr Ala Tyr Arg Asp Val Gly 85 90 95 Val Tyr * <210> 1234 <211> 147 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11589..12029) <400> 1234 Met Pro Trp Gln Pro Leu Arg Arg Cys Thr Glu Pro Gly Cys Asn Arg 1 5 10 15 Arg Val Lys Ser Gly Lys Cys Glu Glu His Arg Arg Ala Ala Trp Arg 20 25 30 Ala Glu Asp Ala Arg Arg Gly His Arg Arg Ala Arg Gly Tyr Ser Arg 35 40 45 Gln Trp Asp Lys Tyr Arg Ala Met Tyr Leu Ser Lys Asn Pro Leu Cys 50 55 60 Val Arg Cys Leu Glu Lys Gly Ile Tyr Thr Pro Ala Val Val Val Asp 65 70 75 80 His Ile Ile Pro Ile Asp Gly Gly Asp Asp Val Leu Phe Trp Pro Glu 85 90 95 Trp Asn His Gln Pro Leu Cys Gln Ala Cys His Asn Gln Lys Thr Lys 100 105 110 Trp Leu Asp Pro Ala Thr Lys Ser Lys Arg Ala Ala Gly Gly Phe Arg 115 120 125 Glu Glu Glu Glu Arg Ala Ala Asn Arg Asn Asn Trp Met Tyr Asp Ala 130 135 140 Asp Glu * 145 <210> 1235 <211> 58 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12022..12195) <400> 1235 Met Asn Glu Arg Glu Gln Asn Arg Leu Ile Arg Gly Leu Ile Arg Gln 1 5 10 15 Arg Asp Ala Trp Lys Thr Gln Glu Thr Gly His Lys Asp Lys Ala Ser 20 25 30 Gly Arg Ala Glu Arg Ile Thr Ala Lys Arg Leu Thr Asp Arg Asp Arg 35 40 45 Glu Val Met Glu Cys Phe Arg Asn Arg * 50 55 <210> 1236 <211> 119 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12319..12675) <400> 1236 Met Ala Arg Pro Pro Lys Ala Pro Ala Tyr Leu Asp Asp Ile Ala Val 1 5 10 15 Lys Gln Trp Arg Glu Lys Ser Arg Gln Leu Ala Glu Arg Gly Asp Leu 20 25 30 Thr Pro Ala Asp Trp Ser Asn Leu Glu Leu Tyr Cys Val Asn Tyr Ser 35 40 45 Ile Tyr Arg Lys Ala Val Ala Asp Leu Ala Ala Arg Gly Phe Ser Ile 50 55 60 Val Asn Ser Gln Gly Gly Glu Ser Arg Asn Pro Ala Leu Ser Ala Lys 65 70 75 80 Ser Asp Ala Glu Arg Val Met Ile Lys Met Ala Ser Leu Leu Gly Phe 85 90 95 Asp Pro Ile Ser Arg Arg Lys Asn Pro Pro Glu Thr Glu Glu Glu Asp 100 105 110 Glu Leu Asp Arg Leu Glu * 115 <210> 1237 <211> 554 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12659..14320) <400> 1237 Leu Thr Ala Trp Asn Lys Tyr Ala Glu Asp Val Lys Thr Gly Lys Ile 1 5 10 15 Pro Ala Cys Lys Arg Leu Lys Gln Ala Val Lys Arg Tyr Phe Ser Asp 20 25 30 Leu Lys Ser Pro Leu Tyr Thr Phe Asp Arg Glu Val Val Glu Arg Phe 35 40 45 Ile Ala Phe Ser Arg Val Cys Pro His Val Lys Gly Pro Met Arg Gly 50 55 60 Arg Pro Ile Glu Leu Glu Pro Trp Gln Gln Phe Ala Phe Ala Cys Ile 65 70 75 80 Leu Gly Phe Lys Val Lys Ala Thr Gly Arg Arg Lys Tyr Thr Ser Ala 85 90 95 Phe Ile Glu Val Pro Arg Lys Asn Ala Lys Ser Thr Thr Ala Ala Ile 100 105 110 Leu Ala Asn Trp Phe Leu Ile Met Glu Asn Gly Gln Gln Asp Ile Tyr 115 120 125 Thr Ala Ala Val Ser Arg Asp Gln Ala Arg Ile Val Phe Asp Asp Ala 130 135 140 Arg Gln Met Cys Leu Leu Ser Arg Pro Leu Arg Arg Arg Val Asn Ile 145 150 155 160 Gln Ala His Lys Val Ile His Pro Lys Ser Asn Ser Leu Leu Lys Pro 165 170 175 Leu Ala Ala Lys Ala Ala Thr Ile Glu Gly Thr Thr Pro Ser Leu Ala 180 185 190 Ile Val Asp Glu Tyr His Leu His Pro Asp Asn Gly Val Tyr Ser Ala 195 200 205 Leu Glu Leu Gly Met Gly Ala Arg Pro Glu Gly Leu Leu Phe Ala Ile 210 215 220 Thr Thr Ser Gly Ser Asn Val Val Ser Ala Cys Lys Gln His Tyr Asp 225 230 235 240 Tyr Cys Cys Gln Ile Leu Asp Gly Glu Glu Val Asn Glu Ser Met Phe 245 250 255 Val Leu Ile Tyr Glu Leu Asp Asp Glu Ser Glu Val Asp Asp Pro Ala 260 265 270 Met Trp Ile Lys Ala Asn Pro Asn Ile Asp Val Ser Val Asp Arg Glu 275 280 285 Lys Leu Ala Ser Thr Ile Gln Lys Ala Arg Gly Ile Pro Ser Gln Trp 290 295 300 Val Glu Met Met Thr Lys Arg Phe Asn Ile Trp Cys Gln Gly Ala Thr 305 310 315 320 Pro Trp Met Gly Asn Gly Ala Trp Ala Glu Cys Ala Gly Thr Phe Thr 325 330 335 Glu Glu Asp Leu His Gly Gln Glu Cys Tyr Ala Gly Leu Asp Leu Ser 340 345 350 Ser Thr Ser Asp Ile Ser Ser Val Cys Tyr Ala Phe Pro Val Gly Lys 355 360 365 Thr Ile Met Leu Ile Ser Arg His Tyr Leu Pro Glu Phe Gln Leu Gln 370 375 380 Asn Pro Ala Asn Lys Asn Arg Ala Val Tyr Arg Gln Trp Ala Lys Ala 385 390 395 400 Gly Trp Ile Arg Thr Thr Pro Gly Asp Cys Ile Asp Tyr Asp Arg Ile 405 410 415 Arg Asp Asp Ile Met Gln Asp Ala Glu Lys Phe His Ile Arg Leu Val 420 425 430 Gly Phe Asp Thr Trp Asn Ala Thr His Leu Arg Thr Gln Leu Gln Gly 435 440 445 Ala Gly Phe Glu Val Glu Pro Phe Pro Gln Thr Tyr Leu Arg Phe Ser 450 455 460 Pro Ala Ala Lys Ser Phe Glu Val Phe Val Asn Arg Arg Val Ile Val 465 470 475 480 His Arg Gly Asp Pro Val Leu Ser Trp Ser Met Ser Asn Val Val Met 485 490 495 Gln Ser Asp Ala Asn Ala Asn Ile Lys Pro Asn Lys Lys Lys Ser Pro 500 505 510 Asn Lys Ile Asp Pro Ser Val Ala Ala Leu Met Ala Phe Gly Thr Phe 515 520 525 Gln Ala Glu His Glu Asp Phe Ala Phe Asp Ile Ser Asp Ser His Arg 530 535 540 Gln Lys Leu Glu Glu Phe Ser Gly Val * 545 550 <210> 1238 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14334..14615) <400> 1238 Met Thr Glu Ala Glu Leu Leu Gly Leu Ile Arg Arg Val Ser Gly Ile 1 5 10 15 Ser Gln Gln Ala Asp Glu Gln Thr Thr Gln Pro Asp Ser Val Thr Ala 20 25 30 Glu Asn Tyr Ala Arg Val Val Ala Glu Val Met Cys Arg Asp Gly Ile 35 40 45 Gln Leu Asn Asp Val Asp Met Arg Asn Ile Arg Ile Arg Val Leu Glu 50 55 60 Met Leu Ala Tyr Asn Arg Arg Val Glu Leu His Arg Glu Lys Glu Lys 65 70 75 80 Ile Thr Tyr His Trp Lys Lys Pro Glu Arg Leu Arg Arg * 85 90 <210> 1239 <211> 92 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(14920..15195) <400> 1239 Val Gly Phe Thr Cys Ser Val Gly Val Met Ile Ile Val Ile Pro Phe 1 5 10 15 Pro Gln Trp Gly Lys Ser Ser Asn Arg Asn Asp Val Arg Cys Gly Cys 20 25 30 Leu Asp Gly Leu Arg Gly His Tyr Asp His Ser Gln Lys Gln His Ile 35 40 45 Arg Cys Phe Ser Val Pro Arg Pro Pro Gln Ile Glu Glu Val Glu Ser 50 55 60 Ile Asn Gln Leu Pro Arg Arg Leu Pro Gln Ile Glu Val Pro Glu Asn 65 70 75 80 Ile Ser Gly Leu Thr Ile Lys Leu Ala Ser Asn * 85 90 <210> 1240 <211> 15381 <212> DNA <213> Escherichia coli O157:H7 <400> 1240 tagcacctcc tgagcaggca atggccaccg tttatctaac agtggccatt tgatttgagg 60 aaatgatgaa acattattca gaaaattaat ttaaaaaaac cattccttaa gtcaaatata 120 tataaacgcc gaatagcgat taaatccttc tcaaagaatg cactgataac attgtgttat 180 ttttattgcc tcatttttct cactcactta tagttggtcc ctgctggcag taatttagtc 240 atttcagaga tttttactct gatgtgcact tactgactta tctcacaagt aattttttct 300 ctaaataaag aatagtgatg ccagcaatta cagttaaaac ttgctttact cgtaaaaaca 360 atactttaat ggggttctaa tgagacatta catgaaatgg tttgcggcta ttgctgttgt 420 gggtgcttta gcaggttgcg cgcgtactgc gccaattgat caggttcact caaccgtcag 480 cgctggtcat acccaggaac aagtgaaaaa agcgattctg aaagctggcg ttgaacgcaa 540 atggattatg tccgaagccg gacaaggcat aattaaagca cgtcaacagt cacgcgatca 600 ttcagcggaa atacgcatta actacacggc atccagctac gatatcaatt atgaaaatag 660 ccagaaccta caagcgtcag gcggacaaat tcataaaaac tacaatcgct gggtccgcaa 720 tctcgacaaa gatattcaac tgaatttgtc agcgggcgca gatttataat tcttcctaaa 780 gtcgggccgt tgcggtccga taataattta attccctctt aacaggttgt gcccaacatg 840 tacgaacagg attctcttag cgcactggat gcgattaccg aagctcaacg cattgccttt 900 gcccctatgc tttttcaaac agcactctgc ctacgtaatg cgggtgtact ttcatatctg 960 gatcggcaag gcaaacatgg cgcaacgctg gctgatatca ccgaacatag ccatatcaac 1020 gaatatgcta ccagcgttct gttagatatg ggcttaagcg ggcgaattat tacctgtaaa 1080 gagggaattt attacctggc gaaaatcggt cattacctcc tgcatgacac tatgactcgc 1140 gtgaatatgg atttcaccca ggatgtctgt taccaggggc tcttcttcct cgccgattca 1200 ctcaatgaag gaaaaccttc cgggttaaaa gtatttggcg actggtcgac gatatatccg 1260 gcactttcgc aattaccaga cgccgctcgt gaagctggtt tgcgtttgat cattactatt 1320 cagatggcgc atttaacgcc gcactgcctt atgtattcgc caaccaaccc cacaacaaca 1380 ttgtacgatg ttggcggcaa tacgggtaag tgggctttgc gttgctgcaa atacaatgaa 1440 aacatcgccg ttacgttatt agatctgcca caacaaatcg tactagcgaa agaaaatatc 1500 gcgaatgcag gtttttctga tcgcatagat ttccatgcgg tggatatgct aagcgatgcc 1560 ccattaccgg gcgaggctga tatctggtgg atgagccaat ttttagactg tttttcaccc 1620 gaacaaataa ttagcatact cagcaaaatt gccagcgtaa tgaagcctgg cgcaaaagtt 1680 tgcatcatgg agttgttctg ggatgcgcag cggtttgaag cagcatcgtt tagcctgaac 1740 gcgtcctcac tttattttac ctgcatggca aacggtaaca gccgtttcta tagtgcagag 1800 aaattttacg actatctgaa taaagcagga ttccaggtag cagagcgcca cgataattta 1860 ggcgttgggc atacactttt gatatgccaa aagaaataat cgtcacttaa taattttggt 1920 ttaccgcggg cgcgcgttga tgaaatttgc attaaacatt ctcgactggc aggcaagagc 1980 gcctggactt agtgaaacgc tgcaatggca ggagtggtca cgtcagcctc aggcaattga 2040 cccgacagca ccgttggcaa aattaagtga actgccaatg atgaccgccc gccgcctcag 2100 ctccgggagc aaactggctg ttgaatgcgg tctggcaatg ctacgccgcc atcaaccaga 2160 cgccgttttg tataccagtc gtcatggcga actggagcgc aattaccgca ttgttcatgc 2220 actggcaacc gaacaggcgc tttctccgac ggacttcgcg ctctccgtac acaactcttc 2280 cgtgggtaac ctgaccattg cggccaaaca gccgagcgtt tcgtcatcgc tttcggctgg 2340 tcgcgatagt ttccagcaag gtttgtgtga agtgcttagc ctgctacaag cgggatacca 2400 gcgcgtgctg atggtcgatt ttgacggttt cctgcccgag ttttatcacc cacaactgcc 2460 atcagaaatg ccgacctggc cgtacgccgt cgcgctggtg attgaagctg gcgatgactg 2520 gcaatgtgaa acgcagtcag ccattgcggg caatgaaaca acactgccgc aaagcatgtt 2580 gtttttacag cactatttac aaaatgtaga cacattttca ctgcctggcg agcgcgtgca 2640 atggcgctgg agccacagat gagtaagctg atgtcacgtc tggagtggac ctggcgactg 2700 gtcatgaccg ggttatgttt tgccctgttt ggtctcggcg gcctgctgct ttctgtcgtg 2760 tggtttaaca tattgttagt tttggtgtgg gatacttccc gccgccgtcg tttggcgcgt 2820 cgcagcattg ccgccagttt tcgcctgttt ttaactgtcg cgaaagggct tggcgtactg 2880 gattatcgta ttgatggcgc tgaaatctta catcaggaac gcggttgcct cgtcgtagcc 2940 aatcatccca cgctgatcga ttacgtgctg ctggcgtcag tcatgccaga aactgactgc 3000 ctggtgaaaa gcgcgctgtt aaaaaatcct tttcttggcg gcgtcgtgcg ggcgacagat 3060 tatttaatca acagcgaagc tgaaactctg ttaccccgct gccaacagcg actggcacag 3120 ggtgacacta tcctgatttt ccccgaaggc acacgaacga agcccggtga aaaaatgacg 3180 ctgcagcgcg gggcggcgaa tattgccgtg cgctgcgcca gcgatttacg catcgtgaca 3240 atcggctgta gcgagcatct gctggataaa caaagtaaat ggtatgacgt tccacctgac 3300 cggccgtttt ttacggttgc agtccatggt cgggttgaaa tcaataaatt ttacgatgca 3360 acttcacaag aaccggcgct ggcagcaagg cagttaaacc ggcatctttt gcttcaatta 3420 caacaaggtt gtttacctct ctcaggaata aataatgcaa gcgctttatc tggaaattaa 3480 aaacctcatc atcagcaccc tcaatctgga cgagttgacg cctgatgata tcgataccga 3540 cgcgccgctg tttggcgacg gtttagggct ggactctatc gatgccctgg aactgggact 3600 ggcagtaaaa aatgagtacg gcatcgtgct ctctgcggaa agcgaagaga tgcgtcagca 3660 ctttttctcc gtcgccactc tggcctcttt cattgctgcg caacgtgcct gaggaaagcc 3720 atcatgacag aacaacaaac cgtctatcag gaagtctcag ccctgctggt taagctgttt 3780 gaaatcgatc cgcaggacat caaacctgaa acgcgcctgt acgaagatct ggaactggac 3840 agcatcgacg ccgttgacat gattgtgcac ctgcaaaaga aaaccggtaa gaaaatcaag 3900 ccggaagagt ttaaagcagt gcgtacagtc caggatgtcg tcgaggctgt agaacgcctg 3960 ctacaagaag cctgatctga tgtcgggcat tcgctcgcta ccgatgatta agctgctgac 4020 tggattattg ctgctcgcct ggccgtttgt gatttggttt ggcttagcgc ataacggcct 4080 gcactggctg ttaccgctaa tggcgttgct gcttttgttg cgtctgcgcc agacccgtcg 4140 ccaggcgggg cctttacaag ccgtcacgca actcgtcgct gtcgtgggca tcgcattatg 4200 tgtcgccagc tttatgttga aaacgcacca gctactgctg ttttacccgg tagtggttaa 4260 cgcggtcatg ctggcggttt ttggcggttc gctgtggtcg gcaatgccga tagttgagcg 4320 gctggcgcgg ttgcaggagc cagacctccc ggaaaagggc gtgcgctata cccgccacgt 4380 cacgcaaatc tggtgcggct ttttcatcat taacggtgga attgccctct ttaccgcgct 4440 ttatgccgat atgtcgttat ggaccgcctg gaacggcatg attgcttatt tgttgatggg 4500 gacgttaatg gctggtgaat ggctgctgcg ccgtcaggtg atgaaaagag atcgcgcatg 4560 aagcagacct taccgcttgc acgctggctg actgcgccac gccctgatga cacacccatt 4620 gcgtggctga acgaaagtac ctggacgctg ggcgatttgc gtcacgatgt cgcgcaactt 4680 atctgccgct tgcagcaaca gccgggtgaa cgctgggcgc tgtgctttga gaacagctat 4740 ctgtttatcg ttgccctgct cgccacgcta cacgccggaa aaacgccggt gcttccgggg 4800 cataaccgtg ttatccagct taacgagcaa cgtgaacttt ttgatggtgt gcttagcgac 4860 agcgaactta actggcaagg ttcattgctg ttggtagcaa gttctccaca aatcgcgaca 4920 caatccttca cctttgccgc tatagcgcca gaggctttta tcgagctgtt tacctccggt 4980 tccacgggac agccgaaacg ggcgattaaa cctgttcatt tgctggatcg tgaagcagaa 5040 ctgctggctg aacgattagg cgcacgtctg gcgggttgtc gtgtcgtcgg ttccgtattg 5100 ccgcagcatt tgtacggcct gacttttcgc gttttcctgc ccatggcgtt gggattaccg 5160 ctgcacgccg ccatgctctg gtatgtcgaa cagtttgccg cgttgagtca tcagcatcgc 5220 tatatcttca tcagcagccc ggcatttttg aagcgcctgg atacccagct ttctccgcca 5280 cccgttcagg tgcttctctc tgctggcggt gagctgccgt ggcaggatgt acaacatacc 5340 gcgagctggc tgcgcgtctg gcctgatgaa atctacggca gcacggaaac tggcgtcatc 5400 gcctggcgct accgcgaaca agagcaacgc cgctggctac ccctcccagg tatgcagttc 5460 caggccgaag gcgatgcctt tcgcctcttt tcaccgctga tagcggaaga taacggcatg 5520 ttactcgacg atatcttaca gtttagcgaa gatggtcagt tccatctgat ggggcgtcgt 5580 gggcgcatcg ttaagattga agaaaaacgt atttcactcc aggaagtaga acaacgtcta 5640 ctggcgctgg acggcattcg cgaggcggcg gcagttcccg ttacgcgcgg cgggcgtcag 5700 agcataggcg ttttgctggt gctggatgac gaagctcatc tgcaatggca gaacggcggc 5760 gggcatagcc aggaaatgac ctggcggcgt ttactgcgcc cgacgctgga gccagttgct 5820 attccgcgtt actggcgcgt tattgatgaa atgccagtaa acagtatgaa caagcgtgtc 5880 tatgcgcaat tacaggagtt atttcatgaa gccccatgaa atcgagcgcc atcaggcaca 5940 aacgaatcac cttgaaattg ttctgcatct cagggcggat ctgttctggt ttcgcggtca 6000 ttttgccgtg caaccattac tcccaggagt tgcgcaaatc gactgggcga tgagctacgc 6060 gctcaatctg ctcgcgcctg gctggcgttt tcactccatt cagaacataa aattccagtc 6120 tccgttgctg ccggaaaacc gcgtcacgct cgcgcttaac tggcaggaag aacgccagat 6180 tctgagcttt agctatcagc gtcacgacgg tgacgcccgc cacaccgcca gtagcgggaa 6240 gatccgccta tgtcggtaaa cttttctccc tgcgtgttga taccctgcta caaccacggc 6300 gcgatgatgc cgggcgtgct ggcgcgtctt aagccattta atctgccctg tattgtggtg 6360 gatgacggca gcgatgccac cacacaacag caactggaca gtctgcttgc cgaacagcct 6420 ggcgtgacct taattcgcct ggcagaaaac gcaggcaaag gcgcggcggt gatgcgtggc 6480 ttacaggcag cggcagacgc agggttcagc catgcggtgc aggtggatgc tgacggtcag 6540 cacgcgattg aagatatccc taaactgctg gctctcgctg aacaacaacc tgcggcactg 6600 atctccggcc agccaattta cgatgactcc atcccccgct cacggcttta cgggcgctgg 6660 gtcacccacg tctgggtatg gatcgaaacg ctctccctgc aactgaaaga cagcatgtgc 6720 ggttttcgcg tttatccggt tgcgccaacg ctgcaactgg caaaacacgc caccatcggc 6780 aagcggatgg atttcgacac cgaagtgatg gtgcgcctct actggcaggg aaataccagc 6840 tatttcgtgc cgacccgcgt cacctatcca ctggacgggc tttcgcattt tgatgccctg 6900 aaagataacg tccgcatctc gctcatgcac acgcgtctgt ttttcggcat gttgccgcgt 6960 attccttcac tgctgatgcg ccgctcttcc tgccactggg cgcggcagag tgaagtgaaa 7020 ggattatggg gaatgcgcct gatgctgctg gtctggcgtc tgctgggaag aacggcgttt 7080 agcgcgctgc tttacccggt ggtgggcgtc tactggctca ctgcttctcg tgcgcgcaaa 7140 gcgtcgcaag actggctcgc ccgtgtacga cagcatcaac cacaggcggc aaaactcaac 7200 agctatcagc actttctacg tttcggtaat gccatgctcg acaaaatcgc cagctggcgc 7260 ggcgagctac aaccagggcg tgatgtgctg tttgcgccag gcgcagaagc agcgcttgac 7320 gtccgcgatc cgcgcggcaa attgctgctg gcctcgcatc ttggcgatgt ggaagtgtgc 7380 cgggcgctgg caaaaattca gggctacaaa accattaacg cgctggtgtt tagcgaaaac 7440 gcccaacgct ttaaacagat aatgcaggag atggctcctc aggcaggcat taacctgatg 7500 ccggtaacag atatcggccc agaaaccgcc atcctgctga aagagaagct ggataacggc 7560 gaatgggtgg cgattgtcgg tgaccgcatc gccgtcaacc cgcaacgcgg cggcgactgg 7620 cgcgtctgct ggagttcgtt tatgggccag cctgcgcctt tcccacaggg gccgtttatt 7680 ctcgcctcta ttttgcgctg cccggtgaat ctgattttcg ccctgcgcca gcacggcaag 7740 ctgcatattc actgcgaaag ctttgccgac ccactgcagc tgccgcgcgg cgaacgccaa 7800 caggcgctgc aaaacgctat cgatcattac gccgcgcgtc tggaacatta cgcgctccag 7860 tcgcctctcg actggtttaa ttttttcgat ttctggcaac tgccggaaat tcaggacaag 7920 gagtaaaggg tgctgaacga tccccgattt accgcagaag tcgagctgac cattcccttt 7980 cacgacgtcg atatgatggg cgtggcctgg cacggtaact attttcgcta ctttgaagtg 8040 gctcgcgagg cgctgctcaa ccagttcaat tacggctatc ggcaaatgaa agagtccggt 8100 tatttgtggc cagtggtcga tgcgcgggtg aaatatcgcc acgccctcac ctttgagcaa 8160 cgcatccgcg tgcgtgcgca tatcgaagag ttcgaaaacc gtctgcggat tggctatcag 8220 attttcgatg ccgaaacggg caaacgcgcc accaccggat acaccattca ggtcgcggtc 8280 gacgagcaaa gtcgcgaact gtgctttgtc agccccgata ttctgtttga acgcatggga 8340 gtcaaaccat gaaattttta ccgctgctgg cgctgctgat tagcccgttt gtgagcgccc 8400 tgaccctgga cgatcttcag caacgcttta ccgaacaacc ggtgatccgc gcccatttcg 8460 atcaaacccg gacgattaaa gatctgccgc agccgctgcg atctcagggc cagatgttga 8520 tcgcccgcga ccaggggctg ttgtgggatc aaacctcacc gttccccatg caactattac 8580 tggacgataa acgcatggtg caggtgatca acggtcagcc gccgcaaatc atcacggcag 8640 aaaacaaccc gcagatgttc cagtttaacc acctgctgcg cgcgttgttc caggccgatc 8700 gcaaagtgct ggaacaaaac ttccgcgtcg aatttgctga caaaggcgaa ggccgctgga 8760 cgctgcgcct gacgccgacc accacgccgc tggataaaat tttcaacacc atcgatctcg 8820 ccgggaaaac ctatctggag agcattcaac ttaatgataa acagggcgat cgcaccgata 8880 ttgctcttac ccaacatcaa ctgacgccag cgcaactgac cgatgacgaa cgccaacgtt 8940 ttgccgccca gtaaacgccc cgcgctgtta tgggggctag tctgcctggt catggcggtg 9000 gcgttgctga tcctgctgcc gcaatcacgg ctgaacagta gcgtgctggc tatgttaccc 9060 aaacagacga tgggcgatat tcctccggcg ctgaatgacg gctttatgca gcgtcttgac 9120 cgccaactgg tgtggctggt cagccccggt aaagaggcta atcctttggt cgctcaggag 9180 tggctgacgc tgctgcaaaa atccgctgcg ctcggcgacg ttaaagggcc aatggatgcc 9240 gccagccagc aggcgtgggg agcgtttttc tggcagcatc gcaacggcct gattgacccc 9300 aacacccgcg cccgcctgca aaacggcggc gaagcgcagg cacagtggat cctctcccag 9360 ctttattccg cattctccgg cgtaagcggc aaggagctgc aaaacgatcc gctgatgtta 9420 atgcgcggct cgcagctggc aatggcgaaa aacggccagc gtttgcggct gatggacggt 9480 tggctggtga cgcaggatcc ccagggcaac tactggtatc tgctgcacgg cgaactggcg 9540 ggatcgtcgt ttgatatgca gcaaacccac cagctgatca cgaccctgaa tacgctggaa 9600 aaggatctga aaacgcgtta cccgcaggca cagttgctct cgcgcggcac ggtgttttac 9660 agcgattacg ccagccaaca ggcgaagcag gatatctcca ccctgggcgt ggctacgctg 9720 ctgggggtga tattgctgat tgtggcggtg ttccgctctt tacgcccgtt gctgctttgc 9780 gtgatttcca tcggcatcgg cgcgctggcg ggaacggtcg ccactttatt gattttcggt 9840 gaattacacc tgatgacgct ggtgatgagc atgagcgtta tcggcatttc cgctgactac 9900 acgctctatt atctcaccga gcggatggtt cacggcaacg acgtttcgcc gtggcaaagc 9960 ctggcgaaag tacgcaatgc cttgctactg gcgctgctca ccaccgtggc ggcgtatctg 1002 0 attatgatgc tcgccccctt ccccggcatt cgccagatgg cgatttttgc cgccgtcggg 1008 0 ttgagcgcct cctgtctgac cgtcctgttc tggcatccgt ggctgtgccg tggcctgccg 1014 0 gtgcgtccgg ttccggcgat ggcgctgatg ctacgctggc tggcagcgtg gcggcgtaat 1020 0 aaaaaactgt cgctgggtct gcccgtcgcg ctggcgctgt tttcgctggc ggggatgtca 1026 0 atgctacgcg tcgatgacga tatctcgcag ttacaggcgc taccgcagca tattctggcg 1032 0 caggaaaaag ccattaccgc cctgaccggg cagagcgtcg atcaaaaatg gtttgtggtt 1038 0 tacggcgatt cgccacagca aacattgcgg cgactggaga aatataccgc ctcacttgag 1044 0 tatgcgaaaa aagaggggct tatcagcaac taccgcacca ttccgctgaa ctcccttgcg 1050 0 cggcaggagg aagatttaca actgctgaaa acggcggccc cgacagtaac aaaagcgctg 1056 0 caaaatgccg ggctgacggc agtgaacccg gatctcaacg ccatgccagt gaacgttgat 1062 0 gaatggctgg caagccccgc cagtgaaggc tggcgtctgc tgtggctgac gctggaaaac 1068 0 ggcgaaagcg gcgtactggt gccggttgaa ggggttaaaa gtagcgcgtt gatgcaggaa 1074 0 atcgccacat attacccttg cggcattgcc tgggttgatc gcaaaagcac ctttgatgaa 1080 0 ttgttcgcac tttaccgcta cgtcttaacc ggcttgttgc tggtggcgct ggcagtgatt 1086 0 gcctgcggcg cagtggcccg tctcggctgg cgcaaagggc ttatcagcct ggtgccttcg 1092 0 gtgctttcgc tgggctgtgg tctggcggtg ctggcgatga gcgggcaggc ggtgaatctc 1098 0 ttttcgctgc tggcgctggt gctggtgctt ggcatcggta tcaactacac gctgtttttc 1104 0 agtaatccgc gcggtacacc gttaacttcg ctactggcga tcgcgctggc aatgctcacc 1110 0 accttgctga cgctgggtat gctggtattc agcgccaccc aggccatcag cagttttggc 1116 0 attgtgctgg tgagcggtat tttcaccgcc ttcctgcttt cgccgctggc tatgcccgat 1122 0 aaaaagagaa caaaaaaatg atcaaatcca cattctggcg agcgttcgcc ctgaccgcta 1128 0 cgcttatcct caccggctgt agccactcgc aaccagaaca ggaaggccgc ccgcaggcgt 1134 0 ggctgcaacc tggcacgcgc atcacgctgc cggcaccagg gatttcaccc gcagtcaatt 1140 0 cgcagcaact gttgaccggc agcttcaacg gcaaaaccca gtcgctgtta gtgatgctta 1146 0 acgccgacga tcagaaaatc acccttgccg ggctgtcgtc ggtcggcatt cgcctgtttc 1152 0 tggtgaccta cgatgcgcaa gggctacgcg ccgagcaatc catcgtcgtc ccacagttac 1158 0 cgcccgcaag tcaggtactg gctgacgtga tgctcagcca ctggccgatt agcgcctggc 1164 0 aaccgcaact tcccgcagga tggacacttc gcgacaacgg tgacaaacgc gagctgcgta 1170 0 acgccagcgg caaactggtc acggaaatca cctatctgaa tcgcaagggc aaacgcgtgc 1176 0 caatcagcat tgagcagcat gtctttaaat accacatcac cattcaatac ttaggtgact 1182 0 gatatgattt atatttccgc cgtcggcatg atcaacgccc tgggaaataa ccttgacgaa 1188 0 atcgcaacca acctgactcg cggtgttgct cccggcatgc gcccgcgcgc aggctggttg 1194 0 caggggcatc cgcaggcggt cctggctggc gtggatggcg agcttccgct tatcccggaa 1200 0 aaattcgctg cgcaccgctc gcgcaacaat cagatcctgc tggcggcgct ggcgcagatc 1206 0 cagccgcagg ttgatgacgc cattgcgaaa tatggccgcg agcgcattgc gattgtgctt 1212 0 ggtaccagca cctccggcct gcatgaaggc gacacgcacg ttaacctgcg cacccacggg 1218 0 cagccgagca ccacatggca ctacgcgcaa caggaactcg gcgatccgtc gcgttttctc 1224 0 agccactggc tggcgctcga cggcccggcc tatacccttt caaccgcctg ctcttccagc 1230 0 gccagagcga taatcagcgg gcgcaggctt atcgaagcgg ggctggtcga tgccgccatt 1236 0 gtgggtggcg cagacaccct gagccggatg ccgattaacg gttttcacag cctcgaatcg 1242 0 ctgtcgccaa ccttatgtca gccgtttggt cgtgaccgcg caggtatcac cattggtgaa 1248 0 ggggcggggc taatgctgct gacccgggaa ccgcagccca tcgcgttgct gggcgttggt 1254 0 gaatcgagcg acgcttacca tatttcagcc ccgcatccgc agggcgaagg agcgatccgc 1260 0 gctattaatc aggcgctgac cgatgcgcag cttacgccag atgacgtcgg ctatatcaac 1266 0 ctgcacggca ccgccacaca actcaacgat cagattgaat caatggtggt taacgccctg 1272 0 tttggcgaac gcgtaccgtg cagctccacc aaacatttga ccggacacac gctgggcaca 1278 0 gcgggcatta ccgaggcggc aattagtatg ttgattttac agcgtgattt accgctgccc 1284 0 gctcaggact tcagcctgtc gccgcgcgat cccacgctgc caccgtgtgg cattatcgaa 1290 0 aaaccgcagc cgctggcacg tccggtgatc ctgtccaatt ccttcgcctt tggcggcaat 1296 0 aacgccagca ttctgctcgg gagggtttcg tgagccacta tttatccccc ggcgcttatc 1302 0 tgccccacga cgcgcccatg ttactgctgg aagacgtggt gagcgtcagc gatgacagcg 1308 0 cggtgtgccg cgtgacggtt tcgcccagtg gcgtactggc accgtttctc gacccggacg 1314 0 gcaatctccc cggctggttt acccttgaac tgatggcgca aaccgtcggc gtctggtctg 1320 0 gctggcatcg ccaccagcag ggcaaaaaca gtattgagtt agggatgata ctgggcgcgc 1326 0 gtgaattgct ttgcaccact ggcattctgc ccgcaggcca gacactgacc attaccgtca 1332 0 aactgctgat gcaagacgat cgcttcggca gttttgagtg cagcatcaac gacggcgagg 1338 0 cgacgggccg cattaacacc ttccagccga ccgcggaaga acttaccacc ctgtttcaac 1344 0 aaggagcgtc ctgatgagtc gttcagttct ggttactggt gccagcaaag gcattggtcg 1350 0 cgccatcgcc tgccaactgg cggcagacgg ctttaacatt ggcgttcact atcaccgtga 1356 0 cgccacaggc gctcaggaaa cgctgaatgc cattgtcgcc aatgggggta acgggcgttt 1362 0 gctcagtttc gacgtcgcaa accgcgaaca gtgtcgggaa gtgctggagc acgaaatcgc 1368 0 gcaacacggt gcctggtacg gcgtggtcag taacgccggg atcgcccgcg atgccgcttt 1374 0 tccggcttta agcgatgacg actgggatgc ggtgatccac accaacctcg acagtttcta 1380 0 caacgtcatt cagccgtgca ttatgccgat gatcggcgca cgccagggtg ggcgcatcat 1386 0 cacgctatcc tcggtttccg gcgtaatggg caatcgcggc caggtgaatt acagcgctgc 1392 0 caaagccgga attatcggcg caacaaaagc gctggctatc gaactcgcga agcgcaaaat 1398 0 caccgtcaac tgcatcgcgc cggggcttat tgataccggg atgatcgaaa tggaagagag 1404 0 cgccctgaaa gaggcaatgt cgatgatccc catgaaacgc atgggccagg cggaagaagt 1410 0 tgccgggctt gccagctatt taatgtctga tattgcgggt tacgtcaccc gccaggttat 1416 0 ttccatcaac ggagggatgt tatgacacgt cgcgtagtga ttacaggaat gggcggcgtg 1422 0 actgcctttg gtgaaaactg gcaggacgtt tctgcacgct tactggcata tgaaaatgcg 1428 0 gtgcgcaaaa tgccggagtg gcaggtctac gatgggctgc acaccctgct tggcgcgcct 1434 0 gttgatgatt tcacgctacc ggagcactac acccgcaagc gtatccgtgc gatgggccgc 1440 0 gtgtcgcaaa tgtcgacccg tgccagcgag ctggcgttag agcaggcagg gttgattggc 1446 0 gatccgatat taaccagcgg cgaaacgggc attgcgtacg gttcatcgac cggcagtacc 1452 0 ggcccggtaa gcgagttcgc caccatgctg acggaaaagc acaccaataa catcactggc 1458 0 accacctatg tgcagatgat gccgcacacc accgccgtta atactggcct ctttttcggc 1464 0 ctgcgcgggc gggtgatccc aacctccagc gcctgtactt ccggcagcca ggcaatcggt 1470 0 tatgcgtggg aagccattcg ccacggttat caaacggtga tggttgctgg tggtgccgaa 1476 0 gagttatgtc cttcagaagc agcggtattt gatacgcttt tcgccaccag ccagcacaat 1482 0 gatgcgccga aaaccacacc ttcaccgttc gatgaaaacc gcgacgggct ggtgattggt 1488 0 gaaggcgcag gtacgctcat tctcgaagaa ctggagcacg ccaaagcgcg cggcgcgacc 1494 0 atttacggtg aaatcgtcgg ctttgcgact aactgcgacg cggcacatat tacccagccg 1500 0 cagcgcgaaa ccatgcagta ttgtatggag caatcgctga aaatcgccgg gttaagcgca 1506 0 caagatatcg gctatatttc agcgcatggt acggcgaccg atcgcggtga tatggcagaa 1512 0 agtctggcga cagcaaccat ttacggtgat aatgtgccgc tctcctcgct gaaaagttat 1518 0 tttggtcata cgcttggtgc ctgtggcgcg ctcgaagcct ggatgagtct gcaaatgatg 1524 0 cgcgaaggtt ggtttgcgcc tacgctaaac ctgaataaac cagacccgaa ttgtggcgcg 1530 0 ctggattaca tcatgcatga agcccgcaag gttgattgtg agtttttgca gagtaacaac 1536 0 tttgcctttg gcggcattaa t 1538 1 <210> 1241 <211> 126 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(392..769) <400> 1241 Met Lys Trp Phe Ala Ala Ile Ala Val Val Gly Ala Leu Ala Gly Cys 1 5 10 15 Ala Arg Thr Ala Pro Ile Asp Gln Val His Ser Thr Val Ser Ala Gly 20 25 30 His Thr Gln Glu Gln Val Lys Lys Ala Ile Leu Lys Ala Gly Val Glu 35 40 45 Arg Lys Trp Ile Met Ser Glu Ala Gly Gln Gly Ile Ile Lys Ala Arg 50 55 60 Gln Gln Ser Arg Asp His Ser Ala Glu Ile Arg Ile Asn Tyr Thr Ala 65 70 75 80 Ser Ser Tyr Asp Ile Asn Tyr Glu Asn Ser Gln Asn Leu Gln Ala Ser 85 90 95 Gly Gly Gln Ile His Lys Asn Tyr Asn Arg Trp Val Arg Asn Leu Asp 100 105 110 Lys Asp Ile Gln Leu Asn Leu Ser Ala Gly Ala Asp Leu * 115 120 125 <210> 1242 <211> 354 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(838..1899) <400> 1242 Met Tyr Glu Gln Asp Ser Leu Ser Ala Leu Asp Ala Ile Thr Glu Ala 1 5 10 15 Gln Arg Ile Ala Phe Ala Pro Met Leu Phe Gln Thr Ala Leu Cys Leu 20 25 30 Arg Asn Ala Gly Val Leu Ser Tyr Leu Asp Arg Gln Gly Lys His Gly 35 40 45 Ala Thr Leu Ala Asp Ile Thr Glu His Ser His Ile Asn Glu Tyr Ala 50 55 60 Thr Ser Val Leu Leu Asp Met Gly Leu Ser Gly Arg Ile Ile Thr Cys 65 70 75 80 Lys Glu Gly Ile Tyr Tyr Leu Ala Lys Ile Gly His Tyr Leu Leu His 85 90 95 Asp Thr Met Thr Arg Val Asn Met Asp Phe Thr Gln Asp Val Cys Tyr 100 105 110 Gln Gly Leu Phe Phe Leu Ala Asp Ser Leu Asn Glu Gly Lys Pro Ser 115 120 125 Gly Leu Lys Val Phe Gly Asp Trp Ser Thr Ile Tyr Pro Ala Leu Ser 130 135 140 Gln Leu Pro Asp Ala Ala Arg Glu Ala Gly Leu Arg Leu Ile Ile Thr 145 150 155 160 Ile Gln Met Ala His Leu Thr Pro His Cys Leu Met Tyr Ser Pro Thr 165 170 175 Asn Pro Thr Thr Thr Leu Tyr Asp Val Gly Gly Asn Thr Gly Lys Trp 180 185 190 Ala Leu Arg Cys Cys Lys Tyr Asn Glu Asn Ile Ala Val Thr Leu Leu 195 200 205 Asp Leu Pro Gln Gln Ile Val Leu Ala Lys Glu Asn Ile Ala Asn Ala 210 215 220 Gly Phe Ser Asp Arg Ile Asp Phe His Ala Val Asp Met Leu Ser Asp 225 230 235 240 Ala Pro Leu Pro Gly Glu Ala Asp Ile Trp Trp Met Ser Gln Phe Leu 245 250 255 Asp Cys Phe Ser Pro Glu Gln Ile Ile Ser Ile Leu Ser Lys Ile Ala 260 265 270 Ser Val Met Lys Pro Gly Ala Lys Val Cys Ile Met Glu Leu Phe Trp 275 280 285 Asp Ala Gln Arg Phe Glu Ala Ala Ser Phe Ser Leu Asn Ala Ser Ser 290 295 300 Leu Tyr Phe Thr Cys Met Ala Asn Gly Asn Ser Arg Phe Tyr Ser Ala 305 310 315 320 Glu Lys Phe Tyr Asp Tyr Leu Asn Lys Ala Gly Phe Gln Val Ala Glu 325 330 335 Arg His Asp Asn Leu Gly Val Gly His Thr Leu Leu Ile Cys Gln Lys 340 345 350 Lys * <210> 1243 <211> 195 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2078..2662) <400> 1243 Met Met Thr Ala Arg Arg Leu Ser Ser Gly Ser Lys Leu Ala Val Glu 1 5 10 15 Cys Gly Leu Ala Met Leu Arg Arg His Gln Pro Asp Ala Val Leu Tyr 20 25 30 Thr Ser Arg His Gly Glu Leu Glu Arg Asn Tyr Arg Ile Val His Ala 35 40 45 Leu Ala Thr Glu Gln Ala Leu Ser Pro Thr Asp Phe Ala Leu Ser Val 50 55 60 His Asn Ser Ser Val Gly Asn Leu Thr Ile Ala Ala Lys Gln Pro Ser 65 70 75 80 Val Ser Ser Ser Leu Ser Ala Gly Arg Asp Ser Phe Gln Gln Gly Leu 85 90 95 Cys Glu Val Leu Ser Leu Leu Gln Ala Gly Tyr Gln Arg Val Leu Met 100 105 110 Val Asp Phe Asp Gly Phe Leu Pro Glu Phe Tyr His Pro Gln Leu Pro 115 120 125 Ser Glu Met Pro Thr Trp Pro Tyr Ala Val Ala Leu Val Ile Glu Ala 130 135 140 Gly Asp Asp Trp Gln Cys Glu Thr Gln Ser Ala Ile Ala Gly Asn Glu 145 150 155 160 Thr Thr Leu Pro Gln Ser Met Leu Phe Leu Gln His Tyr Leu Gln Asn 165 170 175 Val Asp Thr Phe Ser Leu Pro Gly Glu Arg Val Gln Trp Arg Trp Ser 180 185 190 His Arg * <210> 1244 <211> 270 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2671..3480) <400> 1244 Met Ser Arg Leu Glu Trp Thr Trp Arg Leu Val Met Thr Gly Leu Cys 1 5 10 15 Phe Ala Leu Phe Gly Leu Gly Gly Leu Leu Leu Ser Val Val Trp Phe 20 25 30 Asn Ile Leu Leu Val Leu Val Trp Asp Thr Ser Arg Arg Arg Arg Leu 35 40 45 Ala Arg Arg Ser Ile Ala Ala Ser Phe Arg Leu Phe Leu Thr Val Ala 50 55 60 Lys Gly Leu Gly Val Leu Asp Tyr Arg Ile Asp Gly Ala Glu Ile Leu 65 70 75 80 His Gln Glu Arg Gly Cys Leu Val Val Ala Asn His Pro Thr Leu Ile 85 90 95 Asp Tyr Val Leu Leu Ala Ser Val Met Pro Glu Thr Asp Cys Leu Val 100 105 110 Lys Ser Ala Leu Leu Lys Asn Pro Phe Leu Gly Gly Val Val Arg Ala 115 120 125 Thr Asp Tyr Leu Ile Asn Ser Glu Ala Glu Thr Leu Leu Pro Arg Cys 130 135 140 Gln Gln Arg Leu Ala Gln Gly Asp Thr Ile Leu Ile Phe Pro Glu Gly 145 150 155 160 Thr Arg Thr Lys Pro Gly Glu Lys Met Thr Leu Gln Arg Gly Ala Ala 165 170 175 Asn Ile Ala Val Arg Cys Ala Ser Asp Leu Arg Ile Val Thr Ile Gly 180 185 190 Cys Ser Glu His Leu Leu Asp Lys Gln Ser Lys Trp Tyr Asp Val Pro 195 200 205 Pro Asp Arg Pro Phe Phe Thr Val Ala Val His Gly Arg Val Glu Ile 210 215 220 Asn Lys Phe Tyr Asp Ala Thr Ser Gln Glu Pro Ala Leu Ala Ala Arg 225 230 235 240 Gln Leu Asn Arg His Leu Leu Leu Gln Leu Gln Gln Gly Cys Leu Pro 245 250 255 Leu Ser Gly Ile Asn Asn Ala Ser Ala Leu Ser Gly Asn * 260 265 <210> 1245 <211> 86 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3455..3712) <400> 1245 Met Gln Ala Leu Tyr Leu Glu Ile Lys Asn Leu Ile Ile Ser Thr Leu 1 5 10 15 Asn Leu Asp Glu Leu Thr Pro Asp Asp Ile Asp Thr Asp Ala Pro Leu 20 25 30 Phe Gly Asp Gly Leu Gly Leu Asp Ser Ile Asp Ala Leu Glu Leu Gly 35 40 45 Leu Ala Val Lys Asn Glu Tyr Gly Ile Val Leu Ser Ala Glu Ser Glu 50 55 60 Glu Met Arg Gln His Phe Phe Ser Val Ala Thr Leu Ala Ser Phe Ile 65 70 75 80 Ala Ala Gln Arg Ala * 85 <210> 1246 <211> 84 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3724..3975) <400> 1246 Met Thr Glu Gln Gln Thr Val Tyr Gln Glu Val Ser Ala Leu Leu Val 1 5 10 15 Lys Leu Phe Glu Ile Asp Pro Gln Asp Ile Lys Pro Glu Thr Arg Leu 20 25 30 Tyr Glu Asp Leu Glu Leu Asp Ser Ile Asp Ala Val Asp Met Ile Val 35 40 45 His Leu Gln Lys Lys Thr Gly Lys Lys Ile Lys Pro Glu Glu Phe Lys 50 55 60 Ala Val Arg Thr Val Gln Asp Val Val Glu Ala Val Glu Arg Leu Leu 65 70 75 80 Gln Glu Ala * <210> 1247 <211> 194 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3980..4561) <400> 1247 Met Ser Gly Ile Arg Ser Leu Pro Met Ile Lys Leu Leu Thr Gly Leu 1 5 10 15 Leu Leu Leu Ala Trp Pro Phe Val Ile Trp Phe Gly Leu Ala His Asn 20 25 30 Gly Leu His Trp Leu Leu Pro Leu Met Ala Leu Leu Leu Leu Leu Arg 35 40 45 Leu Arg Gln Thr Arg Arg Gln Ala Gly Pro Leu Gln Ala Val Thr Gln 50 55 60 Leu Val Ala Val Val Gly Ile Ala Leu Cys Val Ala Ser Phe Met Leu 65 70 75 80 Lys Thr His Gln Leu Leu Leu Phe Tyr Pro Val Val Val Asn Ala Val 85 90 95 Met Leu Ala Val Phe Gly Gly Ser Leu Trp Ser Ala Met Pro Ile Val 100 105 110 Glu Arg Leu Ala Arg Leu Gln Glu Pro Asp Leu Pro Glu Lys Gly Val 115 120 125 Arg Tyr Thr Arg His Val Thr Gln Ile Trp Cys Gly Phe Phe Ile Ile 130 135 140 Asn Gly Gly Ile Ala Leu Phe Thr Ala Leu Tyr Ala Asp Met Ser Leu 145 150 155 160 Trp Thr Ala Trp Asn Gly Met Ile Ala Tyr Leu Leu Met Gly Thr Leu 165 170 175 Met Ala Gly Glu Trp Leu Leu Arg Arg Gln Val Met Lys Arg Asp Arg 180 185 190 Ala * <210> 1248 <211> 454 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4558..5919) <400> 1248 Met Lys Gln Thr Leu Pro Leu Ala Arg Trp Leu Thr Ala Pro Arg Pro 1 5 10 15 Asp Asp Thr Pro Ile Ala Trp Leu Asn Glu Ser Thr Trp Thr Leu Gly 20 25 30 Asp Leu Arg His Asp Val Ala Gln Leu Ile Cys Arg Leu Gln Gln Gln 35 40 45 Pro Gly Glu Arg Trp Ala Leu Cys Phe Glu Asn Ser Tyr Leu Phe Ile 50 55 60 Val Ala Leu Leu Ala Thr Leu His Ala Gly Lys Thr Pro Val Leu Pro 65 70 75 80 Gly His Asn Arg Val Ile Gln Leu Asn Glu Gln Arg Glu Leu Phe Asp 85 90 95 Gly Val Leu Ser Asp Ser Glu Leu Asn Trp Gln Gly Ser Leu Leu Leu 100 105 110 Val Ala Ser Ser Pro Gln Ile Ala Thr Gln Ser Phe Thr Phe Ala Ala 115 120 125 Ile Ala Pro Glu Ala Phe Ile Glu Leu Phe Thr Ser Gly Ser Thr Gly 130 135 140 Gln Pro Lys Arg Ala Ile Lys Pro Val His Leu Leu Asp Arg Glu Ala 145 150 155 160 Glu Leu Leu Ala Glu Arg Leu Gly Ala Arg Leu Ala Gly Cys Arg Val 165 170 175 Val Gly Ser Val Leu Pro Gln His Leu Tyr Gly Leu Thr Phe Arg Val 180 185 190 Phe Leu Pro Met Ala Leu Gly Leu Pro Leu His Ala Ala Met Leu Trp 195 200 205 Tyr Val Glu Gln Phe Ala Ala Leu Ser His Gln His Arg Tyr Ile Phe 210 215 220 Ile Ser Ser Pro Ala Phe Leu Lys Arg Leu Asp Thr Gln Leu Ser Pro 225 230 235 240 Pro Pro Val Gln Val Leu Leu Ser Ala Gly Gly Glu Leu Pro Trp Gln 245 250 255 Asp Val Gln His Thr Ala Ser Trp Leu Arg Val Trp Pro Asp Glu Ile 260 265 270 Tyr Gly Ser Thr Glu Thr Gly Val Ile Ala Trp Arg Tyr Arg Glu Gln 275 280 285 Glu Gln Arg Arg Trp Leu Pro Leu Pro Gly Met Gln Phe Gln Ala Glu 290 295 300 Gly Asp Ala Phe Arg Leu Phe Ser Pro Leu Ile Ala Glu Asp Asn Gly 305 310 315 320 Met Leu Leu Asp Asp Ile Leu Gln Phe Ser Glu Asp Gly Gln Phe His 325 330 335 Leu Met Gly Arg Arg Gly Arg Ile Val Lys Ile Glu Glu Lys Arg Ile 340 345 350 Ser Leu Gln Glu Val Glu Gln Arg Leu Leu Ala Leu Asp Gly Ile Arg 355 360 365 Glu Ala Ala Ala Val Pro Val Thr Arg Gly Gly Arg Gln Ser Ile Gly 370 375 380 Val Leu Leu Val Leu Asp Asp Glu Ala His Leu Gln Trp Gln Asn Gly 385 390 395 400 Gly Gly His Ser Gln Glu Met Thr Trp Arg Arg Leu Leu Arg Pro Thr 405 410 415 Leu Glu Pro Val Ala Ile Pro Arg Tyr Trp Arg Val Ile Asp Glu Met 420 425 430 Pro Val Asn Ser Met Asn Lys Arg Val Tyr Ala Gln Leu Gln Glu Leu 435 440 445 Phe His Glu Ala Pro * 450 <210> 1249 <211> 118 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5906..6259) <400> 1249 Met Lys Pro His Glu Ile Glu Arg His Gln Ala Gln Thr Asn His Leu 1 5 10 15 Glu Ile Val Leu His Leu Arg Ala Asp Leu Phe Trp Phe Arg Gly His 20 25 30 Phe Ala Val Gln Pro Leu Leu Pro Gly Val Ala Gln Ile Asp Trp Ala 35 40 45 Met Ser Tyr Ala Leu Asn Leu Leu Ala Pro Gly Trp Arg Phe His Ser 50 55 60 Ile Gln Asn Ile Lys Phe Gln Ser Pro Leu Leu Pro Glu Asn Arg Val 65 70 75 80 Thr Leu Ala Leu Asn Trp Gln Glu Glu Arg Gln Ile Leu Ser Phe Ser 85 90 95 Tyr Gln Arg His Asp Gly Asp Ala Arg His Thr Ala Ser Ser Gly Lys 100 105 110 Ile Arg Leu Cys Arg * 115 <210> 1250 <211> 559 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6250..7926) <400> 1250 Met Ser Val Asn Phe Ser Pro Cys Val Leu Ile Pro Cys Tyr Asn His 1 5 10 15 Gly Ala Met Met Pro Gly Val Leu Ala Arg Leu Lys Pro Phe Asn Leu 20 25 30 Pro Cys Ile Val Val Asp Asp Gly Ser Asp Ala Thr Thr Gln Gln Gln 35 40 45 Leu Asp Ser Leu Leu Ala Glu Gln Pro Gly Val Thr Leu Ile Arg Leu 50 55 60 Ala Glu Asn Ala Gly Lys Gly Ala Ala Val Met Arg Gly Leu Gln Ala 65 70 75 80 Ala Ala Asp Ala Gly Phe Ser His Ala Val Gln Val Asp Ala Asp Gly 85 90 95 Gln His Ala Ile Glu Asp Ile Pro Lys Leu Leu Ala Leu Ala Glu Gln 100 105 110 Gln Pro Ala Ala Leu Ile Ser Gly Gln Pro Ile Tyr Asp Asp Ser Ile 115 120 125 Pro Arg Ser Arg Leu Tyr Gly Arg Trp Val Thr His Val Trp Val Trp 130 135 140 Ile Glu Thr Leu Ser Leu Gln Leu Lys Asp Ser Met Cys Gly Phe Arg 145 150 155 160 Val Tyr Pro Val Ala Pro Thr Leu Gln Leu Ala Lys His Ala Thr Ile 165 170 175 Gly Lys Arg Met Asp Phe Asp Thr Glu Val Met Val Arg Leu Tyr Trp 180 185 190 Gln Gly Asn Thr Ser Tyr Phe Val Pro Thr Arg Val Thr Tyr Pro Leu 195 200 205 Asp Gly Leu Ser His Phe Asp Ala Leu Lys Asp Asn Val Arg Ile Ser 210 215 220 Leu Met His Thr Arg Leu Phe Phe Gly Met Leu Pro Arg Ile Pro Ser 225 230 235 240 Leu Leu Met Arg Arg Ser Ser Cys His Trp Ala Arg Gln Ser Glu Val 245 250 255 Lys Gly Leu Trp Gly Met Arg Leu Met Leu Leu Val Trp Arg Leu Leu 260 265 270 Gly Arg Thr Ala Phe Ser Ala Leu Leu Tyr Pro Val Val Gly Val Tyr 275 280 285 Trp Leu Thr Ala Ser Arg Ala Arg Lys Ala Ser Gln Asp Trp Leu Ala 290 295 300 Arg Val Arg Gln His Gln Pro Gln Ala Ala Lys Leu Asn Ser Tyr Gln 305 310 315 320 His Phe Leu Arg Phe Gly Asn Ala Met Leu Asp Lys Ile Ala Ser Trp 325 330 335 Arg Gly Glu Leu Gln Pro Gly Arg Asp Val Leu Phe Ala Pro Gly Ala 340 345 350 Glu Ala Ala Leu Asp Val Arg Asp Pro Arg Gly Lys Leu Leu Leu Ala 355 360 365 Ser His Leu Gly Asp Val Glu Val Cys Arg Ala Leu Ala Lys Ile Gln 370 375 380 Gly Tyr Lys Thr Ile Asn Ala Leu Val Phe Ser Glu Asn Ala Gln Arg 385 390 395 400 Phe Lys Gln Ile Met Gln Glu Met Ala Pro Gln Ala Gly Ile Asn Leu 405 410 415 Met Pro Val Thr Asp Ile Gly Pro Glu Thr Ala Ile Leu Leu Lys Glu 420 425 430 Lys Leu Asp Asn Gly Glu Trp Val Ala Ile Val Gly Asp Arg Ile Ala 435 440 445 Val Asn Pro Gln Arg Gly Gly Asp Trp Arg Val Cys Trp Ser Ser Phe 450 455 460 Met Gly Gln Pro Ala Pro Phe Pro Gln Gly Pro Phe Ile Leu Ala Ser 465 470 475 480 Ile Leu Arg Cys Pro Val Asn Leu Ile Phe Ala Leu Arg Gln His Gly 485 490 495 Lys Leu His Ile His Cys Glu Ser Phe Ala Asp Pro Leu Gln Leu Pro 500 505 510 Arg Gly Glu Arg Gln Gln Ala Leu Gln Asn Ala Ile Asp His Tyr Ala 515 520 525 Ala Arg Leu Glu His Tyr Ala Leu Gln Ser Pro Leu Asp Trp Phe Asn 530 535 540 Phe Phe Asp Phe Trp Gln Leu Pro Glu Ile Gln Asp Lys Glu * 545 550 555 <210> 1251 <211> 141 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7930..8352) <400> 1251 Val Leu Asn Asp Pro Arg Phe Thr Ala Glu Val Glu Leu Thr Ile Pro 1 5 10 15 Phe His Asp Val Asp Met Met Gly Val Ala Trp His Gly Asn Tyr Phe 20 25 30 Arg Tyr Phe Glu Val Ala Arg Glu Ala Leu Leu Asn Gln Phe Asn Tyr 35 40 45 Gly Tyr Arg Gln Met Lys Glu Ser Gly Tyr Leu Trp Pro Val Val Asp 50 55 60 Ala Arg Val Lys Tyr Arg His Ala Leu Thr Phe Glu Gln Arg Ile Arg 65 70 75 80 Val Arg Ala His Ile Glu Glu Phe Glu Asn Arg Leu Arg Ile Gly Tyr 85 90 95 Gln Ile Phe Asp Ala Glu Thr Gly Lys Arg Ala Thr Thr Gly Tyr Thr 100 105 110 Ile Gln Val Ala Val Asp Glu Gln Ser Arg Glu Leu Cys Phe Val Ser 115 120 125 Pro Asp Ile Leu Phe Glu Arg Met Gly Val Lys Pro * 130 135 140 <210> 1252 <211> 202 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8349..8954) <400> 1252 Met Lys Phe Leu Pro Leu Leu Ala Leu Leu Ile Ser Pro Phe Val Ser 1 5 10 15 Ala Leu Thr Leu Asp Asp Leu Gln Gln Arg Phe Thr Glu Gln Pro Val 20 25 30 Ile Arg Ala His Phe Asp Gln Thr Arg Thr Ile Lys Asp Leu Pro Gln 35 40 45 Pro Leu Arg Ser Gln Gly Gln Met Leu Ile Ala Arg Asp Gln Gly Leu 50 55 60 Leu Trp Asp Gln Thr Ser Pro Phe Pro Met Gln Leu Leu Leu Asp Asp 65 70 75 80 Lys Arg Met Val Gln Val Ile Asn Gly Gln Pro Pro Gln Ile Ile Thr 85 90 95 Ala Glu Asn Asn Pro Gln Met Phe Gln Phe Asn His Leu Leu Arg Ala 100 105 110 Leu Phe Gln Ala Asp Arg Lys Val Leu Glu Gln Asn Phe Arg Val Glu 115 120 125 Phe Ala Asp Lys Gly Glu Gly Arg Trp Thr Leu Arg Leu Thr Pro Thr 130 135 140 Thr Thr Pro Leu Asp Lys Ile Phe Asn Thr Ile Asp Leu Ala Gly Lys 145 150 155 160 Thr Tyr Leu Glu Ser Ile Gln Leu Asn Asp Lys Gln Gly Asp Arg Thr 165 170 175 Asp Ile Ala Leu Thr Gln His Gln Leu Thr Pro Ala Gln Leu Thr Asp 180 185 190 Asp Glu Arg Gln Arg Phe Ala Ala Gln * 195 200 <210> 1253 <211> 750 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8992..11241) <400> 1253 Met Ala Val Ala Leu Leu Ile Leu Leu Pro Gln Ser Arg Leu Asn Ser 1 5 10 15 Ser Val Leu Ala Met Leu Pro Lys Gln Thr Met Gly Asp Ile Pro Pro 20 25 30 Ala Leu Asn Asp Gly Phe Met Gln Arg Leu Asp Arg Gln Leu Val Trp 35 40 45 Leu Val Ser Pro Gly Lys Glu Ala Asn Pro Leu Val Ala Gln Glu Trp 50 55 60 Leu Thr Leu Leu Gln Lys Ser Ala Ala Leu Gly Asp Val Lys Gly Pro 65 70 75 80 Met Asp Ala Ala Ser Gln Gln Ala Trp Gly Ala Phe Phe Trp Gln His 85 90 95 Arg Asn Gly Leu Ile Asp Pro Asn Thr Arg Ala Arg Leu Gln Asn Gly 100 105 110 Gly Glu Ala Gln Ala Gln Trp Ile Leu Ser Gln Leu Tyr Ser Ala Phe 115 120 125 Ser Gly Val Ser Gly Lys Glu Leu Gln Asn Asp Pro Leu Met Leu Met 130 135 140 Arg Gly Ser Gln Leu Ala Met Ala Lys Asn Gly Gln Arg Leu Arg Leu 145 150 155 160 Met Asp Gly Trp Leu Val Thr Gln Asp Pro Gln Gly Asn Tyr Trp Tyr 165 170 175 Leu Leu His Gly Glu Leu Ala Gly Ser Ser Phe Asp Met Gln Gln Thr 180 185 190 His Gln Leu Ile Thr Thr Leu Asn Thr Leu Glu Lys Asp Leu Lys Thr 195 200 205 Arg Tyr Pro Gln Ala Gln Leu Leu Ser Arg Gly Thr Val Phe Tyr Ser 210 215 220 Asp Tyr Ala Ser Gln Gln Ala Lys Gln Asp Ile Ser Thr Leu Gly Val 225 230 235 240 Ala Thr Leu Leu Gly Val Ile Leu Leu Ile Val Ala Val Phe Arg Ser 245 250 255 Leu Arg Pro Leu Leu Leu Cys Val Ile Ser Ile Gly Ile Gly Ala Leu 260 265 270 Ala Gly Thr Val Ala Thr Leu Leu Ile Phe Gly Glu Leu His Leu Met 275 280 285 Thr Leu Val Met Ser Met Ser Val Ile Gly Ile Ser Ala Asp Tyr Thr 290 295 300 Leu Tyr Tyr Leu Thr Glu Arg Met Val His Gly Asn Asp Val Ser Pro 305 310 315 320 Trp Gln Ser Leu Ala Lys Val Arg Asn Ala Leu Leu Leu Ala Leu Leu 325 330 335 Thr Thr Val Ala Ala Tyr Leu Ile Met Met Leu Ala Pro Phe Pro Gly 340 345 350 Ile Arg Gln Met Ala Ile Phe Ala Ala Val Gly Leu Ser Ala Ser Cys 355 360 365 Leu Thr Val Leu Phe Trp His Pro Trp Leu Cys Arg Gly Leu Pro Val 370 375 380 Arg Pro Val Pro Ala Met Ala Leu Met Leu Arg Trp Leu Ala Ala Trp 385 390 395 400 Arg Arg Asn Lys Lys Leu Ser Leu Gly Leu Pro Val Ala Leu Ala Leu 405 410 415 Phe Ser Leu Ala Gly Met Ser Met Leu Arg Val Asp Asp Asp Ile Ser 420 425 430 Gln Leu Gln Ala Leu Pro Gln His Ile Leu Ala Gln Glu Lys Ala Ile 435 440 445 Thr Ala Leu Thr Gly Gln Ser Val Asp Gln Lys Trp Phe Val Val Tyr 450 455 460 Gly Asp Ser Pro Gln Gln Thr Leu Arg Arg Leu Glu Lys Tyr Thr Ala 465 470 475 480 Ser Leu Glu Tyr Ala Lys Lys Glu Gly Leu Ile Ser Asn Tyr Arg Thr 485 490 495 Ile Pro Leu Asn Ser Leu Ala Arg Gln Glu Glu Asp Leu Gln Leu Leu 500 505 510 Lys Thr Ala Ala Pro Thr Val Thr Lys Ala Leu Gln Asn Ala Gly Leu 515 520 525 Thr Ala Val Asn Pro Asp Leu Asn Ala Met Pro Val Asn Val Asp Glu 530 535 540 Trp Leu Ala Ser Pro Ala Ser Glu Gly Trp Arg Leu Leu Trp Leu Thr 545 550 555 560 Leu Glu Asn Gly Glu Ser Gly Val Leu Val Pro Val Glu Gly Val Lys 565 570 575 Ser Ser Ala Leu Met Gln Glu Ile Ala Thr Tyr Tyr Pro Cys Gly Ile 580 585 590 Ala Trp Val Asp Arg Lys Ser Thr Phe Asp Glu Leu Phe Ala Leu Tyr 595 600 605 Arg Tyr Val Leu Thr Gly Leu Leu Leu Val Ala Leu Ala Val Ile Ala 610 615 620 Cys Gly Ala Val Ala Arg Leu Gly Trp Arg Lys Gly Leu Ile Ser Leu 625 630 635 640 Val Pro Ser Val Leu Ser Leu Gly Cys Gly Leu Ala Val Leu Ala Met 645 650 655 Ser Gly Gln Ala Val Asn Leu Phe Ser Leu Leu Ala Leu Val Leu Val 660 665 670 Leu Gly Ile Gly Ile Asn Tyr Thr Leu Phe Phe Ser Asn Pro Arg Gly 675 680 685 Thr Pro Leu Thr Ser Leu Leu Ala Ile Ala Leu Ala Met Leu Thr Thr 690 695 700 Leu Leu Thr Leu Gly Met Leu Val Phe Ser Ala Thr Gln Ala Ile Ser 705 710 715 720 Ser Phe Gly Ile Val Leu Val Ser Gly Ile Phe Thr Ala Phe Leu Leu 725 730 735 Ser Pro Leu Ala Met Pro Asp Lys Lys Arg Thr Lys Lys * 740 745 <210> 1254 <211> 195 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11238..11822) <400> 1254 Met Ile Lys Ser Thr Phe Trp Arg Ala Phe Ala Leu Thr Ala Thr Leu 1 5 10 15 Ile Leu Thr Gly Cys Ser His Ser Gln Pro Glu Gln Glu Gly Arg Pro 20 25 30 Gln Ala Trp Leu Gln Pro Gly Thr Arg Ile Thr Leu Pro Ala Pro Gly 35 40 45 Ile Ser Pro Ala Val Asn Ser Gln Gln Leu Leu Thr Gly Ser Phe Asn 50 55 60 Gly Lys Thr Gln Ser Leu Leu Val Met Leu Asn Ala Asp Asp Gln Lys 65 70 75 80 Ile Thr Leu Ala Gly Leu Ser Ser Val Gly Ile Arg Leu Phe Leu Val 85 90 95 Thr Tyr Asp Ala Gln Gly Leu Arg Ala Glu Gln Ser Ile Val Val Pro 100 105 110 Gln Leu Pro Pro Ala Ser Gln Val Leu Ala Asp Val Met Leu Ser His 115 120 125 Trp Pro Ile Ser Ala Trp Gln Pro Gln Leu Pro Ala Gly Trp Thr Leu 130 135 140 Arg Asp Asn Gly Asp Lys Arg Glu Leu Arg Asn Ala Ser Gly Lys Leu 145 150 155 160 Val Thr Glu Ile Thr Tyr Leu Asn Arg Lys Gly Lys Arg Val Pro Ile 165 170 175 Ser Ile Glu Gln His Val Phe Lys Tyr His Ile Thr Ile Gln Tyr Leu 180 185 190 Gly Asp * <210> 1255 <211> 390 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11824..12993) <400> 1255 Met Ile Tyr Ile Ser Ala Val Gly Met Ile Asn Ala Leu Gly Asn Asn 1 5 10 15 Leu Asp Glu Ile Ala Thr Asn Leu Thr Arg Gly Val Ala Pro Gly Met 20 25 30 Arg Pro Arg Ala Gly Trp Leu Gln Gly His Pro Gln Ala Val Leu Ala 35 40 45 Gly Val Asp Gly Glu Leu Pro Leu Ile Pro Glu Lys Phe Ala Ala His 50 55 60 Arg Ser Arg Asn Asn Gln Ile Leu Leu Ala Ala Leu Ala Gln Ile Gln 65 70 75 80 Pro Gln Val Asp Asp Ala Ile Ala Lys Tyr Gly Arg Glu Arg Ile Ala 85 90 95 Ile Val Leu Gly Thr Ser Thr Ser Gly Leu His Glu Gly Asp Thr His 100 105 110 Val Asn Leu Arg Thr His Gly Gln Pro Ser Thr Thr Trp His Tyr Ala 115 120 125 Gln Gln Glu Leu Gly Asp Pro Ser Arg Phe Leu Ser His Trp Leu Ala 130 135 140 Leu Asp Gly Pro Ala Tyr Thr Leu Ser Thr Ala Cys Ser Ser Ser Ala 145 150 155 160 Arg Ala Ile Ile Ser Gly Arg Arg Leu Ile Glu Ala Gly Leu Val Asp 165 170 175 Ala Ala Ile Val Gly Gly Ala Asp Thr Leu Ser Arg Met Pro Ile Asn 180 185 190 Gly Phe His Ser Leu Glu Ser Leu Ser Pro Thr Leu Cys Gln Pro Phe 195 200 205 Gly Arg Asp Arg Ala Gly Ile Thr Ile Gly Glu Gly Ala Gly Leu Met 210 215 220 Leu Leu Thr Arg Glu Pro Gln Pro Ile Ala Leu Leu Gly Val Gly Glu 225 230 235 240 Ser Ser Asp Ala Tyr His Ile Ser Ala Pro His Pro Gln Gly Glu Gly 245 250 255 Ala Ile Arg Ala Ile Asn Gln Ala Leu Thr Asp Ala Gln Leu Thr Pro 260 265 270 Asp Asp Val Gly Tyr Ile Asn Leu His Gly Thr Ala Thr Gln Leu Asn 275 280 285 Asp Gln Ile Glu Ser Met Val Val Asn Ala Leu Phe Gly Glu Arg Val 290 295 300 Pro Cys Ser Ser Thr Lys His Leu Thr Gly His Thr Leu Gly Thr Ala 305 310 315 320 Gly Ile Thr Glu Ala Ala Ile Ser Met Leu Ile Leu Gln Arg Asp Leu 325 330 335 Pro Leu Pro Ala Gln Asp Phe Ser Leu Ser Pro Arg Asp Pro Thr Leu 340 345 350 Pro Pro Cys Gly Ile Ile Glu Lys Pro Gln Pro Leu Ala Arg Pro Val 355 360 365 Ile Leu Ser Asn Ser Phe Ala Phe Gly Gly Asn Asn Ala Ser Ile Leu 370 375 380 Leu Gly Arg Val Ser * 385 <210> 1256 <211> 155 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12990..13454) <400> 1256 Val Ser His Tyr Leu Ser Pro Gly Ala Tyr Leu Pro His Asp Ala Pro 1 5 10 15 Met Leu Leu Leu Glu Asp Val Val Ser Val Ser Asp Asp Ser Ala Val 20 25 30 Cys Arg Val Thr Val Ser Pro Ser Gly Val Leu Ala Pro Phe Leu Asp 35 40 45 Pro Asp Gly Asn Leu Pro Gly Trp Phe Thr Leu Glu Leu Met Ala Gln 50 55 60 Thr Val Gly Val Trp Ser Gly Trp His Arg His Gln Gln Gly Lys Asn 65 70 75 80 Ser Ile Glu Leu Gly Met Ile Leu Gly Ala Arg Glu Leu Leu Cys Thr 85 90 95 Thr Gly Ile Leu Pro Ala Gly Gln Thr Leu Thr Ile Thr Val Lys Leu 100 105 110 Leu Met Gln Asp Asp Arg Phe Gly Ser Phe Glu Cys Ser Ile Asn Asp 115 120 125 Gly Glu Ala Thr Gly Arg Ile Asn Thr Phe Gln Pro Thr Ala Glu Glu 130 135 140 Leu Thr Thr Leu Phe Gln Gln Gly Ala Ser * 145 150 <210> 1257 <211> 244 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13454..14185) <400> 1257 Met Ser Arg Ser Val Leu Val Thr Gly Ala Ser Lys Gly Ile Gly Arg 1 5 10 15 Ala Ile Ala Cys Gln Leu Ala Ala Asp Gly Phe Asn Ile Gly Val His 20 25 30 Tyr His Arg Asp Ala Thr Gly Ala Gln Glu Thr Leu Asn Ala Ile Val 35 40 45 Ala Asn Gly Gly Asn Gly Arg Leu Leu Ser Phe Asp Val Ala Asn Arg 50 55 60 Glu Gln Cys Arg Glu Val Leu Glu His Glu Ile Ala Gln His Gly Ala 65 70 75 80 Trp Tyr Gly Val Val Ser Asn Ala Gly Ile Ala Arg Asp Ala Ala Phe 85 90 95 Pro Ala Leu Ser Asp Asp Asp Trp Asp Ala Val Ile His Thr Asn Leu 100 105 110 Asp Ser Phe Tyr Asn Val Ile Gln Pro Cys Ile Met Pro Met Ile Gly 115 120 125 Ala Arg Gln Gly Gly Arg Ile Ile Thr Leu Ser Ser Val Ser Gly Val 130 135 140 Met Gly Asn Arg Gly Gln Val Asn Tyr Ser Ala Ala Lys Ala Gly Ile 145 150 155 160 Ile Gly Ala Thr Lys Ala Leu Ala Ile Glu Leu Ala Lys Arg Lys Ile 165 170 175 Thr Val Asn Cys Ile Ala Pro Gly Leu Ile Asp Thr Gly Met Ile Glu 180 185 190 Met Glu Glu Ser Ala Leu Lys Glu Ala Met Ser Met Ile Pro Met Lys 195 200 205 Arg Met Gly Gln Ala Glu Glu Val Ala Gly Leu Ala Ser Tyr Leu Met 210 215 220 Ser Asp Ile Ala Gly Tyr Val Thr Arg Gln Val Ile Ser Ile Asn Gly 225 230 235 240 Gly Met Leu * <210> 1258 <211> 14181 <212> DNA <213> Escherichia coli O157:H7 <400> 1258 tagatatgcg gcttgaataa cgtataaaaa tgtatcagag tattataaat ttcatgctgt 60 atcagtaata actaagtaaa ggatagctta aaaagaagcc ataatttagt aaattagcga 120 aattatatat attttaaaca ttagtcccat ttggaacgtg ttttcgcatt cccattaaat 180 agatgttggc gatcttttca tttctcttgc tggatttccg cacacagtta taccggcagg 240 aacactttta gtgacaacag cccccatacc tataatggct cccgcgccaa taataagtgg 300 gcgattagga acaccctgct taattactgc acccgagcct atatatgcat tgtcttcaat 360 aacaacatat ccattacatt tagccccagg agcaaatgta acatagtctc ctatttgaca 420 atcatgtgca acgtatgagt atatgtttgc atgaaaaaac ctccctatat gagtattagt 480 agatattgta acaaagggag aaataatagc gccactacct atcatagtat gatcataaac 540 aacgctattt ggatgtttta tagttattgg ttcaaccccg tgtaataata ttgactcaga 600 cactctctgt cgtatcttat cattagcaat agcaacatta aaatactttt ttaaataagg 660 ggcttttaga aagcagttgg ttgaaagcac ttcaaaacca ttaactttct ttcctgccaa 720 aacatcatcc acaaaaacca gagcatagtc agaaccacat tcttgcttta tttgttgatt 780 tagaatgggt attgtttctc taccataact tccagcacca aaaataccat acaaattcat 840 tttcccatct ccaaagaaat atcttatcaa aaccaatgca agattatgaa agcccgcacg 900 ctgcaatgcc tgacgctagg aagtttctgt ccatgactgc ttttcgcatc ttacatgata 960 atcctgcctt gaatacatta tcattgtcag atattaatag cgatgtgccg cattctagaa 1020 aatcattcga atgcaactcg ccttcttata ttatagtcga tttcattcat taccacatca 1080 ggctactgtg caacttattc tccatgcgcc agtgatttcg atttactgtg gcgaacttct 1140 ctgcggttaa agcagcagat ctaatataat atttgatcgt catttcggat tctttctttt 1200 gctctgctat tattgagaga aagtggactg ccattcataa attctgcagc cctttccatt 1260 caaacgtgaa atcaataagc tcatcaggag catctcaaac aatatgaaga cggacatcgt 1320 ctctgccgtg cctcttttca ctaattgcgt aactgtcatg ttttggatta tttaattctt 1380 tcagcgtaaa tatctcctca aagactctat taagccgact cttatttcct tttacagcga 1440 ataaataatc acatctctgt ttttatatct tctctgcaat atctttctgg caagccatcg 1500 catcagttat gattattttt cctttaatac ccatcatttt agaaagttca tgaataactg 1560 tgaacgcatt aggtttctca tccgtcttga tctatccgag gaccagactg tgcattgctg 1620 aaacgcacta atgacatgaa ccactcctct gcgacgactc ttgtcataag tgtgccgaag 1680 tgttttacca tcaattgcga tgacgtcgtt atcatctgga aaatggcaga catgtattca 1740 gttaacaaag cactcgtgaa atattgcagg actgatgcag gatacaactt tggctataat 1800 atcgtaaaca gggataataa aaatctattg tctcaattat tttaagttcc attttgttct 1860 cctttttata taaggcacat ttgttattac ataagcgatg aaaaaatgtc ttaagcaaag 1920 gaacgtctca atcgtgacgt gaaatgcaaa ttggtcagta caaaacttta tttctattaa 1980 tcttttccta gataaagttg cggtatagtc gttatacata aaaaagccca catattcatc 2040 atataccgca ataacattac tttaatataa tcttaaatac gcttaatgat taatgtaaat 2100 aatcactcac ttagcaattt aagaagagct ttagttttct tttccattag ctttacatca 2160 ccgcgtgatt ccacattcaa ccgcaccacc ggttcggtgt tggaggagcg caggttaaag 2220 cgccagtcgg caaaggtcat gctgatgcca tcggtgcgat ccaccgccag cgcctcgcgg 2280 ctaaaatgct gttccacgcg attaattgcc tcaacgggtt gcgccagttt gctgttgatc 2340 tcaccgcttg ccggaaacgc cgccatccgg tcgcgcacca tttcgcccag cgtttttcct 2400 ttcaggcaca ccagttcggc gaccagcagc cacgggatca tgccgctgtc gcagtaagcg 2460 aaatcacgga agtaatggtg agcgctcatt tcgccaccgt agatggcgtc ttccttgcgc 2520 atacgttctt taataaaggc gtgtccggtt ttcgacatta ccggggtgcc gcctgcggca 2580 gtcaccacat caacggtgtt ccaggagaga cgtggatcgt ggatgatctt cgcgccggga 2640 tttttttcga ggaacgcttc tgccagcagg ccgacaatgt agtagccctc gataaactgc 2700 cctttttcgt caaacaggaa acagcggtca aaatcgccat caaaggcaat gcccatatcc 2760 gcgccgtgtt tgatgaccgc attacgggtg tcgtcgcggc attccggcag cagcgggtta 2820 ggaataccgt tggggaaatt gccgtccggc gtgttgtgta ctttgattaa ttccaccggt 2880 gcgccgaggg ctttaaatcg ggcttcaatg gcgtccacca ccggacccgc tgcgccgttc 2940 ccggagttga tcaccagctt gagcggcgtg aggtttttga cgttgatata accgaacagg 3000 tgatcaacgt aagcgtcacg cagattgatt tgctgatagc gaccacgttt ggtttcatcg 3060 acaggaggga agtcattggc ttctgccaga cgctggacat cgcgcagtcc ggtatcaccg 3120 ctgatcgggc gagccccttc gcgcaccagc ttcatgccgt tgtaatccat cgggttatgg 3180 ctggcggtaa cttcgatgcc gccatccact ccgagatgga acgtggcgaa atagatctct 3240 tcggtgccgg acataccgat atccagcaca tcgacgcccg catcctgtaa acctttcgca 3300 agcgccagtt ttaacgcttc gctggtgagg cggacatcac cgcctaaaac aatggttttc 3360 ggtttgagaa attcgccata ggcacgccca atgcgccagg caatatcttc attcagttct 3420 tcgcctaatt tcccgcgaat atcataggct ttaaagcagg ttaaagattt catatgttaa 3480 tcttcatgtt tgtaacgttc tttctgtctt ataatatcat cctctcccaa ataatcccct 3540 gaactgactt caataagatt aagagggatt atgcccggat tctcaagact atacgctgcg 3600 ccaaggggaa tgtatatcga ttcatttgcg gtgactagtt tagttttatc gccaagggtt 3660 acttttgctg taccagaaag cacgatccaa tgttcagaac gatggtgatg catccttaaa 3720 gaaagcccct caccaggttt cacaataatt ttcttgactt tgtatcgctc accttggtca 3780 atcgaatcaa attttcccca tggtcggaaa acttcacgat gactaatata ctctgtacgt 3840 tgctgcaatt taagcatttc gactattttt tttacatgct gtacatcact ctttttagac 3900 acaagaacgg catctttagt ttgcacgata accatatctt caattccaat ggcggctacc 3960 aacgctgact cagagtagat ataattattc ttagtatcat aggttaatat atcaccttta 4020 catacatctc ctgttttcga ttttagacta atgtcccata acgattgcca agatccaacg 4080 tcactccaac caatatcaac agggcataca acacattttt ctgttttttc cattacagca 4140 aaatcaatag attcagcagg acaatcttga aattgttctt ttgataatcg aataaaatct 4200 agatcaatgt atgaggatga ggcaacctgt tcacaaacat tgtaaatgtc aggtctaaat 4260 tttctcaatt cctcaagata aacagatgcc ttaaacatga atattccact attccaatag 4320 tgattaccag aagtcatata caattctgcg gtttcacgat taggcttttc gacaaactta 4380 tttacataat aaaaaccagt attttcatgc ccttgaagcg gtacagatag ttcacctctc 4440 tcaatatacc cataaccagt ttcagcatat tctggtataa ttccaaacgt tacaatttta 4500 ccttgattag cgatgggagt tgcattttta atagcatcac agaaaacact ttctttagct 4560 ataacgtggt ctgccgcaag aactagaagc aatggatctt cctgaggatt acgttttaac 4620 gcatgaaacg cagatatcgc tattgctggt gcagtatttc gcccgcatgg ttctagaata 4680 atattaccat ttaatttatt tatttccctt aactgttcag ccacaacaaa gcgatgctgt 4740 tcatttgtta tcactaatgg tttttgacat gataggcctg aaagtcgtag caaagtcgtt 4800 tgtaacaagg tgttatcacc agagagttgt aaaaactgct ttggatatag ttcacgagaa 4860 agtggccaaa gacgactgcc tgtaccaccg gccataacta cagcaattat tggcgcatca 4920 gacatattat atccttatta tctaagccaa tcgcatcatt tgttttattg ttaaaatatg 4980 cgcgacaatt ataatgcaca tcgtcatcat ttatcagctt tgctcgcgat agccagcaat 5040 aagcattatg ttgtgacttc ggtaatttca aaatgtttgg ttgtaattta agaaggaatg 5100 ctataactat ataatgcgtt gaaaagtctc cccccatact attgtcttcg tagaagtgct 5160 gccagatacc ataaaactta cccacagaga gaggcaaacg aattcctagt tcaatttctg 5220 tcaatcgttc aaaggctgtc tgcaattttt catctttcaa caccctacca ccaggaacga 5280 accaatagcc ctgtgccggg cggttgattc gttttcctag caaaatttcg ccaaactcgt 5340 tttccacaat caaatctata gaaataagag gagtagacct tacaattgtg gcaaagtctt 5400 gggaatgtaa aaacattatt acccccgata ttgaagttgg ttttcaagaa accagttgta 5460 tgtattttca agacccttgt gaagggtaat tttatgattc caacctagtt gatgaagaag 5520 cgttacatca agtagttttc gaggggctcc atcgggcttt gttgtatcga acgtaatatg 5580 ccctttataa cctacaactt ttgctattgt ttccgcaagc tcacaaatcg tgcagtcaat 5640 acctgttcca atattgatat gagacaacat tactttagta tttttttgcc atatatcgta 5700 tggcatctcc atgacataaa tgcttgcaga agccatatca tctacatgta agaattcacg 5760 ctttggagta ccacttcccc aaacaacaac attcggagaa ttgttttcca cagcatcatg 5820 aaagcggcgc aaaagcgccg gaatcacatg agaattactt ggatgaaaat tgtcatttgg 5880 accataaaga ttggttggca ttactgaacg gtaatcacgc ccaaactgac ggttataaga 5940 ttcacataat ttaatacctg caatttttgc gatagcataa ggttcatttg ttggctcaag 6000 tttcccttgt aataattcgt cttccataat cggttggtgt gctaacttag gataaataca 6060 cgacgaaccg aggaaaagca gtttatttac attatttttg tgggcagcat gaatgacatt 6120 cgcctctatc attatattct catatataaa atcggcagga taagaactgt tagctaaaat 6180 acctccgact tttgctgctg ccaaataaac ctggtcgatt ttctgtgaag aaaaaaaatc 6240 caaaacagcg ctactatcca acaagttcaa ttcatcccga gtacgtaaaa ccaactcaac 6300 atcatcacgt tgtttgaggc gtcgggtaat agctgatcca accattcctt ggtgaccagc 6360 aataaaaata cgttgcttat tcatcatcat tccagagcta agcttacaga aaaaccatgc 6420 gattttaaaa gagaatgttt tttagcggct tcaagatctt tggcaaccat ttcagaaatc 6480 atttcagcaa gagtaatttc tggtctccaa ccaagtttga gattagcttt gctcggatct 6540 ccaagcaaag tatcaacttc agctggtcgg aaataacgag gatcaacagc aacaatgaca 6600 tcacctggtt tcacacctgg agcatcctgt ccttcaaccg aatctacaat gcctttttct 6660 tcgattcctt taccaacaaa gctcatctta ataccaagtt gtgctgctgc catttcgaca 6720 aactgacgga ctgagtattg gactcctgtt gcaatcacaa aatcttcggg ttgctcctgt 6780 tgtaacatca accattgcat tctaacataa tcttttgcat gtccccaatc tcgtaacgaa 6840 tccatattcc ctaaatacaa acatgattcc aagccttgtg caatatttgc aagtcctcga 6900 gtaattttcc ttgttacaaa cgtttctcca cggcgtggag attcatgatt gaacaatata 6960 ccattacatg cataaatacc atatgactct cgataattta ccgtgatcca atatgcgtaa 7020 agttttgcaa ctgcataagg ggaacgagga taaaaagggg tggattcttt ttgagggatt 7080 tcctgaacaa gtccatataa ttctgaggtt gaagcttgat agaaacgcgt tttgttttcc 7140 aatcctaaaa agcgaattgc ttccagtaaa cgtaatgtac caattgcatc gacatcggct 7200 gtatattctg gagactcaaa agaaactgct acgtgactca tagcagctaa attatatact 7260 tcatctggct gtacctcctt tagaattcta gtgaggttag atgaatcagt cagatctcca 7320 tagtgcaagt gaaaatttgg gttagaacca tgtggatctt gataaatatg gtctatgcgt 7380 tctgtattaa aagatgaggc tcggcgtttg ataccatgaa cttcataccc tttatcaagc 7440 aaaaactcag ctagataaga tccatcttgt ccagttacac ctgtaataag agcgacttta 7500 gtcattatat acctcttgaa tatattaaga tcgggattca atttcttgtt tcacaacatc 7560 taaaagaaaa tctgcacacg cattgcgtct tttgagaccc aattctatca gagttgtagg 7620 ttcataaaaa attttagatt catcagcttt taccatcgcg tcatttaatg aataatggtt 7680 ttttgcctga aagaaatata catcaccgca attaacttct ttattgacat ctatgtcaga 7740 tagtataact tttttcccta atgcaatagc gtcaaatgtt accccccctc caggcccgcc 7800 ttcaaataag gttggttgta ttacagcaat gcaatttttg attaattcaa tttgttcaag 7860 tttaggtata tgccctaata tcttaatttt cgattcaatt ccgagctttt ttgccaaaac 7920 catcaattca ttaaaatatc cagggaatcg ataatcttga gtagctcccg tgcatactaa 7980 ataaacatca ggattatatt cagtataaat tttaaatgcc ctaaaagcag ttgcatgatc 8040 tttatgtttc caaaattgat tgcaaattat aaaataatcc ttgtcaatat tatatttggc 8100 aatattacca gagtaatcag cgaaccattt taattgaggg catggactaa atggaagaga 8160 atgtagtttt gcagaataat tcccaacata tttatttgca tcggtaataa ctgaatgtgc 8220 attaacaata atattgttag cgcaattgag catcaattta aaaaacacat tcctttgatc 8280 tatttctcgc ttactaaaaa atgaaggata gtaacagtgt tgaaagtcat aaatataacc 8340 aatccatgct tttttattca aatttcccga aggaacacgc atgcaaggaa gaataacatc 8400 acaatcgcta ctatcaaaat atgaataaaa ggcagagctc ttacttttaa taaaggtaag 8460 attcgtctct atattatttt gtgtaaaggc atctctatag tattgctcat taaatctatt 8520 taatgaaatc catcgaggcc tttccctctt taaaattgct tttaatatac ttttaaaagg 8580 aaatgctttt tctcttataa gagaatgtat atcatttctc ggtaaaagaa tatcgataca 8640 tatttctggt ttcgtttcta atattgacag aatatattta ataaaatcaa ttccaccgcc 8700 ccactcgtaa aatccatctg aattcaacgc aattttcatg aatgaccttt acaatatttt 8760 aggctattta tcactataaa attcgttaat agattcacaa atataaataa cttgctcatt 8820 cgataggctg gggaaactag gtaaattaat tccacgccaa ccaagatcct cagctatagg 8880 gtgcttttga tatttttccg agtacattgg catcgtgtgg acagggtaaa aaactggcct 8940 tgtttcgatg agtttatctg caaggtgatt ccttaattcc tctctttcct ctgcggtcct 9000 agttagaatt gagaccatcc aataagtgtg aaaaacatct ttactttcct tgtggacttg 9060 tacaagactg ttgatatttt ttttataaat atcagcaatt tcacgttttc gtgatataaa 9120 atcatcagct tgttctaact gggctaatcc tatagcagcg cagatatttg tcatcctata 9180 attgtagcct ataacgtcat gccaatattg cctatgtaca gctaatcctt ggcctttaaa 9240 atgtaaacaa cggtcataaa gtgttttgtc attcgtgaca accattccac cttcacctgt 9300 agtaatagtt ttatttccaa aaaagctaaa agtagaaata tctccaaatg ttcccacata 9360 tttaccttta tatttagaac caaaggcttc agcgcaatct tcaattacaa acaaatttct 9420 acttttggcc agttctacaa tttgttccat atcacatgga tgtccgtata aatggacaca 9480 cataatagct ttagttttat tagtgatttt ttgttctatg tcactaacag acatttgcca 9540 agtttcatta tctgaatcaa cgaaaatggg ggtggctcct gtgtatttta tagcattaac 9600 tgatgctata tatgtcagtg ttggaacaat aacttcatct ccttccgata tacctaacgc 9660 taacaaagct aaatgaagag caaccgttcc attacttaca gtagttgcat attgcacatg 9720 gttttgttcc gcaaatttat tttcaaactt ctgaatatag tttccttttg atgaaatcca 9780 cgttgagtcc agacattcat ttacatattc tttttctttt cctgtcaatg acggttggta 9840 aactggtata tatttcattt tcatcctctt atatttaact gtctatcgat atgtttttta 9900 aaactacatt tataccatat aaagtaattt acaatatata taaaaatgaa gcagtacaac 9960 ataacagtta acccaaaatg gctaactatg atgtattttg ctggaattgc gatcaatatc 1002 0 aatgttacaa cagcaagcat ttgttgttta actatgttca aaccatttaa aaagcttgca 1008 0 aatgtattcg aaaaagcatc aataacagac cataaagcat aagctattat gaatgttcga 1014 0 ggtacctgaa tctttccttc tgtccaaata ttaacgactt cactaccgaa cactactaat 1020 0 atgaaggcca ataagaatga tgaaataccc actattttca atgatgttct gagcgtcttt 1026 0 tttataaatt gagtatcatt gcgtgcatga gcatctgcat aagcagccca taacgggatg 1032 0 ttataaatcg taagagggac cgtagatatt tgaaataatc tctgtgtaat gctaaaaaca 1038 0 gcaacataag taacacccaa tgttatagat attataaagt tatcaccact ccatgttgcc 1044 0 agagtgccta actgtaaaat aaaaaagaaa aaaccgttta atatcaaata tggagcttct 1050 0 cttttagcat gtatgttaac ttttgtaaac tttattaatc gctttataat aagattaatt 1056 0 gttaaataga ttcccgatat gtattgaata ccaagagtgc tgacaattaa aactggtagt 1062 0 cccgcatgta gtttcgacga tattactaga gtaataatag ataacaatat aaatatggca 1068 0 ttaacaatat tacttatata ggctttttgt attcccatat aaactttttg cacaccattt 1074 0 gaataaattc caagtccaaa tatgattaca aagactttaa ttgagtgttg taactctgca 1080 0 tacacattct cgtttatacc ttttattact agttgccaat caatcatgcc agaagtaata 1086 0 tagcatattg cagttatgac aaacgataat ccagccagca aagtgagccc accactaatt 1092 0 tgccgactca tctttaaatt tttgccacac gcaaatgaat gtgcgatcct gtttgttaat 1098 0 gcatttccta tacctaagtc caaaaatgtc agagcagcac caagactggt aatagtcatc 1104 0 catacaccaa atctctcttg tcctaaataa ggtaaagtta aacttacagt taatataaga 1110 0 gaaagtagtg agagtatttt actaatcaaa cttgaaataa cagacaagga tataatcctg 1116 0 tacctttcct gttctctacc taaagcactt gatgtatcat atttttttaa agtgcaaaat 1122 0 ttaagtattt ttttgatttt attcattatc atatggtgaa ctattcttca tgaagaataa 1128 0 agttagacaa atatattgca ttttccgcaa tactcttctt aaacgttcag ggaataaaat 1134 0 tttgattatt gaaattggaa taaacttaat aaggtttttt ttattttttt caaacataat 1140 0 tttggcaagc tctttatctc ttaaaattct tttttttgaa gatactcccc ccatatcata 1146 0 ttttacataa cccgaagtaa tcaaagatag agatcttaac ccttcaggaa acacctcttg 1152 0 aataagctta taatcagcac atattttata ccttagatca tattctgaat gattctttgg 1158 0 gaaaatcacc ccttgatgac aataccctgt atttgaatgg gttatagaag aaaatcccag 1164 0 aagtttatca ttttcgaaaa ggccaacttt aatcaaacat ggctctttga tatttttata 1170 0 tatatctcca attacgctat cgccggcgtt taaataatgt attaagtcgc ctttggccaa 1176 0 cattcggccc ttattcatcg catcatatat cccttcatct ttttcataaa catgtgtaat 1182 0 attcatacta gtaaatctac taatgacacg attcgttcca tctgtagagc cgccatcaac 1188 0 tataataatc tcaaaaggtt ttatttttaa aattgataaa ctacttaaag ttttttctaa 1194 0 cccttcagca ttattataag tcacagttat aactgatatt ttcatttcgt gataatctct 1200 0 ttaacgtatc atgcaataag atcagaggag tacacattat caatacggag agaaaaggac 1206 0 caaaaaagaa ggccgatgca ttcccagcca ctaagtattg caataaaatc ataatgatat 1212 0 atgaatagaa tgcgcaattt atcgagctat gggttttttt cattctcttt aaaagataaa 1218 0 aaggtatata tatccctaaa gggataatga atacacagag aaaaccaaaa aaaactaaca 1224 0 gttctgctcc atacgtagta actgataaaa aatttgctcc catgtctcca aatacttgtt 1230 0 tatgtaaccg ttctccataa aataagtctt gatgctttat tccctgtatt ctatttatta 1236 0 ttgcttttaa ttccttttct aactctggtg tcggaaagaa atcgttctta atagattcag 1242 0 aaacaacata tggaacactt tcaacttgct ctattgttaa cctattaatt atccttaaca 1248 0 tattattata tgagtcattt tgttctccgt cttgtcctaa acttagataa aacaacgagc 1254 0 atacaacccc taccaataaa aaatacccta ttattctttt tattttagga ttacggttat 1260 0 cctttgacag gatattggta atcaatatat attgaagaat gagcaacacc aattcagaac 1266 0 gataaccaaa taaagcaatc gttgtaaaat atacaaatat gatggtcctc tgtttgaatt 1272 0 tatgctcatc ataaagaata attaatgcaa acacaactat attaccaaaa tacttaatat 1278 0 atctaatgta aagtccatta ccttcagcta ttctaagttt agccccccct ggatcatcat 1284 0 caaatatagg aataccttct ttaagaaata aaactacagc agcaatttct atagtcacaa 1290 0 aaaggaaaac gagtattaac tttagctccc agttcacgat aaattttttc tgctgttttc 1296 0 tttcatttat aatcgttaga taaaataata aaacaaaaaa aatctgaaat ataattataa 1302 0 tactagttaa tacctttgta tcaaaatttg ttatacgatc atctatgata accccataca 1308 0 actggagact ataaagtgta aataggaata aaaaaatcaa cttagccgct gacttcactt 1314 0 tttagtctcc tttctcctta atagtgaatg tgttattttt ttcatgactc catttgaagc 1320 0 atataataaa aaataatata atgtttttgg aaaggacaaa tgtaaatgtt ctctatatat 1326 0 actccatgtc cattttgcag ctttaatttt attacccgat agtgaattat ttgaacgcat 1332 0 gtaatacgcc agattatctt gaatacaaat agcaccattt gttttattaa ttatttccag 1338 0 ccacatcaaa taatcctcgt gaccaatctt tttttgataa aacttaccca atttgttggc 1344 0 attatagatt cctgtcaaat tccctatgta gtttttcatg agcatttttc tataatttat 1350 0 cacatgagga gcattaactt cgccaacaat atttcttttg ttatctataa cataataatt 1356 0 agaacatacc acatctacac attcattatt taacacttcg atttgacgct ctaatttttt 1362 0 ctcgtgccac aaatcatccg catcacaaaa agaaatatat ttccccgtgg ccatttctat 1368 0 tccataattt cgactttctg caacacctaa atttgtcttg ttacgcaata ttcttatttt 1374 0 ctgattgttt ttgtatcgac tgttgattaa tgaaaatgta tcatcggtgc tacaatcgtc 1380 0 aatgatatac aaaacaaaat cttgataaga ttgatgtata attgattcta ctgatgagat 1386 0 tatagttttg gccccattgt aaacgggcat aattattgaa acggtttctt tgttcatttg 1392 0 agaatttctt atatattttt aatgctaata gttttgataa gcattaaaat ttatgcacgc 1398 0 taccgcccct ggcttaatcg ctaccagtgt acgaaatgat aatccatgtt aaaaaaatca 1404 0 tctccaagcg tttattatct tattattcag agggagaaac aagactacca aacaaaaaat 1410 0 acatatctgc acactattta ttcattggta gcatagttaa ttataaaagc tcaacagcag 1416 0 tgatatttat tgatctatag t 1418 1 <210> 1259 <211> 222 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(175..840) <400> 1259 Met Asn Leu Tyr Gly Ile Phe Gly Ala Gly Ser Tyr Gly Arg Glu Thr 1 5 10 15 Ile Pro Ile Leu Asn Gln Gln Ile Lys Gln Glu Cys Gly Ser Asp Tyr 20 25 30 Ala Leu Val Phe Val Asp Asp Val Leu Ala Gly Lys Lys Val Asn Gly 35 40 45 Phe Glu Val Leu Ser Thr Asn Cys Phe Leu Lys Ala Pro Tyr Leu Lys 50 55 60 Lys Tyr Phe Asn Val Ala Ile Ala Asn Asp Lys Ile Arg Gln Arg Val 65 70 75 80 Ser Glu Ser Ile Leu Leu His Gly Val Glu Pro Ile Thr Ile Lys His 85 90 95 Pro Asn Ser Val Val Tyr Asp His Thr Met Ile Gly Ser Gly Ala Ile 100 105 110 Ile Ser Pro Phe Val Thr Ile Ser Thr Asn Thr His Ile Gly Arg Phe 115 120 125 Phe His Ala Asn Ile Tyr Ser Tyr Val Ala His Asp Cys Gln Ile Gly 130 135 140 Asp Tyr Val Thr Phe Ala Pro Gly Ala Lys Cys Asn Gly Tyr Val Val 145 150 155 160 Ile Glu Asp Asn Ala Tyr Ile Gly Ser Gly Ala Val Ile Lys Gln Gly 165 170 175 Val Pro Asn Arg Pro Leu Ile Ile Gly Ala Gly Ala Ile Ile Gly Met 180 185 190 Gly Ala Val Val Thr Lys Ser Val Pro Ala Gly Ile Thr Val Cys Gly 195 200 205 Asn Pro Ala Arg Glu Met Lys Arg Ser Pro Thr Ser Ile * 210 215 220 <210> 1260 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(884..1036) <400> 1260 Leu His Ser Asn Asp Phe Leu Glu Cys Gly Thr Ser Leu Leu Ile Ser 1 5 10 15 Asp Asn Asp Asn Val Phe Lys Ala Gly Leu Ser Cys Lys Met Arg Lys 20 25 30 Ala Val Met Asp Arg Asn Phe Leu Ala Ser Gly Ile Ala Ala Cys Gly 35 40 45 Leu Ser * 50 <210> 1261 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1070..1234) <400> 1261 Met Ala Val His Phe Leu Ser Ile Ile Ala Glu Gln Lys Lys Glu Ser 1 5 10 15 Glu Met Thr Ile Lys Tyr Tyr Ile Arg Ser Ala Ala Leu Thr Ala Glu 20 25 30 Lys Phe Ala Thr Val Asn Arg Asn His Trp Arg Met Glu Asn Lys Leu 35 40 45 His Ser Ser Leu Met Trp * 50 <210> 1262 <211> 37 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1534..1644) <400> 1262 Val Val His Val Ile Ser Ala Phe Gln Gln Cys Thr Val Trp Ser Ser 1 5 10 15 Asp Arg Ser Arg Arg Met Arg Asn Leu Met Arg Ser Gln Leu Phe Met 20 25 30 Asn Phe Leu Lys * 35 <210> 1263 <211> 457 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2103..3473) <400> 1263 Met Lys Ser Leu Thr Cys Phe Lys Ala Tyr Asp Ile Arg Gly Lys Leu 1 5 10 15 Gly Glu Glu Leu Asn Glu Asp Ile Ala Trp Arg Ile Gly Arg Ala Tyr 20 25 30 Gly Glu Phe Leu Lys Pro Lys Thr Ile Val Leu Gly Gly Asp Val Arg 35 40 45 Leu Thr Ser Glu Ala Leu Lys Leu Ala Leu Ala Lys Gly Leu Gln Asp 50 55 60 Ala Gly Val Asp Val Leu Asp Ile Gly Met Ser Gly Thr Glu Glu Ile 65 70 75 80 Tyr Phe Ala Thr Phe His Leu Gly Val Asp Gly Gly Ile Glu Val Thr 85 90 95 Ala Ser His Asn Pro Met Asp Tyr Asn Gly Met Lys Leu Val Arg Glu 100 105 110 Gly Ala Arg Pro Ile Ser Gly Asp Thr Gly Leu Arg Asp Val Gln Arg 115 120 125 Leu Ala Glu Ala Asn Asp Phe Pro Pro Val Asp Glu Thr Lys Arg Gly 130 135 140 Arg Tyr Gln Gln Ile Asn Leu Arg Asp Ala Tyr Val Asp His Leu Phe 145 150 155 160 Gly Tyr Ile Asn Val Lys Asn Leu Thr Pro Leu Lys Leu Val Ile Asn 165 170 175 Ser Gly Asn Gly Ala Ala Gly Pro Val Val Asp Ala Ile Glu Ala Arg 180 185 190 Phe Lys Ala Leu Gly Ala Pro Val Glu Leu Ile Lys Val His Asn Thr 195 200 205 Pro Asp Gly Asn Phe Pro Asn Gly Ile Pro Asn Pro Leu Leu Pro Glu 210 215 220 Cys Arg Asp Asp Thr Arg Asn Ala Val Ile Lys His Gly Ala Asp Met 225 230 235 240 Gly Ile Ala Phe Asp Gly Asp Phe Asp Arg Cys Phe Leu Phe Asp Glu 245 250 255 Lys Gly Gln Phe Ile Glu Gly Tyr Tyr Ile Val Gly Leu Leu Ala Glu 260 265 270 Ala Phe Leu Glu Lys Asn Pro Gly Ala Lys Ile Ile His Asp Pro Arg 275 280 285 Leu Ser Trp Asn Thr Val Asp Val Val Thr Ala Ala Gly Gly Thr Pro 290 295 300 Val Met Ser Lys Thr Gly His Ala Phe Ile Lys Glu Arg Met Arg Lys 305 310 315 320 Glu Asp Ala Ile Tyr Gly Gly Glu Met Ser Ala His His Tyr Phe Arg 325 330 335 Asp Phe Ala Tyr Cys Asp Ser Gly Met Ile Pro Trp Leu Leu Val Ala 340 345 350 Glu Leu Val Cys Leu Lys Gly Lys Thr Leu Gly Glu Met Val Arg Asp 355 360 365 Arg Met Ala Ala Phe Pro Ala Ser Gly Glu Ile Asn Ser Lys Leu Ala 370 375 380 Gln Pro Val Glu Ala Ile Asn Arg Val Glu Gln His Phe Ser Arg Glu 385 390 395 400 Ala Leu Ala Val Asp Arg Thr Asp Gly Ile Ser Met Thr Phe Ala Asp 405 410 415 Trp Arg Phe Asn Leu Arg Ser Ser Asn Thr Glu Pro Val Val Arg Leu 420 425 430 Asn Val Glu Ser Arg Gly Asp Val Lys Leu Met Glu Lys Lys Thr Lys 435 440 445 Ala Leu Leu Lys Leu Leu Ser Glu * 450 455 <210> 1264 <211> 483 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3477..4925) <400> 1264 Met Ser Asp Ala Pro Ile Ile Ala Val Val Met Ala Gly Gly Thr Gly 1 5 10 15 Ser Arg Leu Trp Pro Leu Ser Arg Glu Leu Tyr Pro Lys Gln Phe Leu 20 25 30 Gln Leu Ser Gly Asp Asn Thr Leu Leu Gln Thr Thr Leu Leu Arg Leu 35 40 45 Ser Gly Leu Ser Cys Gln Lys Pro Leu Val Ile Thr Asn Glu Gln His 50 55 60 Arg Phe Val Val Ala Glu Gln Leu Arg Glu Ile Asn Lys Leu Asn Gly 65 70 75 80 Asn Ile Ile Leu Glu Pro Cys Gly Arg Asn Thr Ala Pro Ala Ile Ala 85 90 95 Ile Ser Ala Phe His Ala Leu Lys Arg Asn Pro Gln Glu Asp Pro Leu 100 105 110 Leu Leu Val Leu Ala Ala Asp His Val Ile Ala Lys Glu Ser Val Phe 115 120 125 Cys Asp Ala Ile Lys Asn Ala Thr Pro Ile Ala Asn Gln Gly Lys Ile 130 135 140 Val Thr Phe Gly Ile Ile Pro Glu Tyr Ala Glu Thr Gly Tyr Gly Tyr 145 150 155 160 Ile Glu Arg Gly Glu Leu Ser Val Pro Leu Gln Gly His Glu Asn Thr 165 170 175 Gly Phe Tyr Tyr Val Asn Lys Phe Val Glu Lys Pro Asn Arg Glu Thr 180 185 190 Ala Glu Leu Tyr Met Thr Ser Gly Asn His Tyr Trp Asn Ser Gly Ile 195 200 205 Phe Met Phe Lys Ala Ser Val Tyr Leu Glu Glu Leu Arg Lys Phe Arg 210 215 220 Pro Asp Ile Tyr Asn Val Cys Glu Gln Val Ala Ser Ser Ser Tyr Ile 225 230 235 240 Asp Leu Asp Phe Ile Arg Leu Ser Lys Glu Gln Phe Gln Asp Cys Pro 245 250 255 Ala Glu Ser Ile Asp Phe Ala Val Met Glu Lys Thr Glu Lys Cys Val 260 265 270 Val Cys Pro Val Asp Ile Gly Trp Ser Asp Val Gly Ser Trp Gln Ser 275 280 285 Leu Trp Asp Ile Ser Leu Lys Ser Lys Thr Gly Asp Val Cys Lys Gly 290 295 300 Asp Ile Leu Thr Tyr Asp Thr Lys Asn Asn Tyr Ile Tyr Ser Glu Ser 305 310 315 320 Ala Leu Val Ala Ala Ile Gly Ile Glu Asp Met Val Ile Val Gln Thr 325 330 335 Lys Asp Ala Val Leu Val Ser Lys Lys Ser Asp Val Gln His Val Lys 340 345 350 Lys Ile Val Glu Met Leu Lys Leu Gln Gln Arg Thr Glu Tyr Ile Ser 355 360 365 His Arg Glu Val Phe Arg Pro Trp Gly Lys Phe Asp Ser Ile Asp Gln 370 375 380 Gly Glu Arg Tyr Lys Val Lys Lys Ile Ile Val Lys Pro Gly Glu Gly 385 390 395 400 Leu Ser Leu Arg Met His His His Arg Ser Glu His Trp Ile Val Leu 405 410 415 Ser Gly Thr Ala Lys Val Thr Leu Gly Asp Lys Thr Lys Leu Val Thr 420 425 430 Ala Asn Glu Ser Ile Tyr Ile Pro Leu Gly Ala Ala Tyr Ser Leu Glu 435 440 445 Asn Pro Gly Ile Ile Pro Leu Asn Leu Ile Glu Val Ser Ser Gly Asp 450 455 460 Tyr Leu Gly Glu Asp Asp Ile Ile Arg Gln Lys Glu Arg Tyr Lys His 465 470 475 480 Glu Asp * <210> 1265 <211> 170 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4907..5416) <400> 1265 Met Phe Leu His Ser Gln Asp Phe Ala Thr Ile Val Arg Ser Thr Pro 1 5 10 15 Leu Ile Ser Ile Asp Leu Ile Val Glu Asn Glu Phe Gly Glu Ile Leu 20 25 30 Leu Gly Lys Arg Ile Asn Arg Pro Ala Gln Gly Tyr Trp Phe Val Pro 35 40 45 Gly Gly Arg Val Leu Lys Asp Glu Lys Leu Gln Thr Ala Phe Glu Arg 50 55 60 Leu Thr Glu Ile Glu Leu Gly Ile Arg Leu Pro Leu Ser Val Gly Lys 65 70 75 80 Phe Tyr Gly Ile Trp Gln His Phe Tyr Glu Asp Asn Ser Met Gly Gly 85 90 95 Asp Phe Ser Thr His Tyr Ile Val Ile Ala Phe Leu Leu Lys Leu Gln 100 105 110 Pro Asn Ile Leu Lys Leu Pro Lys Ser Gln His Asn Ala Tyr Cys Trp 115 120 125 Leu Ser Arg Ala Lys Leu Ile Asn Asp Asp Asp Val His Tyr Asn Cys 130 135 140 Arg Ala Tyr Phe Asn Asn Lys Thr Asn Asp Ala Ile Gly Leu Asp Asn 145 150 155 160 Lys Asp Ile Ile Cys Leu Met Arg Gln * 165 <210> 1266 <211> 322 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5419..6384) <400> 1266 Met Asn Lys Gln Arg Ile Phe Ile Ala Gly His Gln Gly Met Val Gly 1 5 10 15 Ser Ala Ile Thr Arg Arg Leu Lys Gln Arg Asp Asp Val Glu Leu Val 20 25 30 Leu Arg Thr Arg Asp Glu Leu Asn Leu Leu Asp Ser Ser Ala Val Leu 35 40 45 Asp Phe Phe Ser Ser Gln Lys Ile Asp Gln Val Tyr Leu Ala Ala Ala 50 55 60 Lys Val Gly Gly Ile Leu Ala Asn Ser Ser Tyr Pro Ala Asp Phe Ile 65 70 75 80 Tyr Glu Asn Ile Met Ile Glu Ala Asn Val Ile His Ala Ala His Lys 85 90 95 Asn Asn Val Asn Lys Leu Leu Phe Leu Gly Ser Ser Cys Ile Tyr Pro 100 105 110 Lys Leu Ala His Gln Pro Ile Met Glu Asp Glu Leu Leu Gln Gly Lys 115 120 125 Leu Glu Pro Thr Asn Glu Pro Tyr Ala Ile Ala Lys Ile Ala Gly Ile 130 135 140 Lys Leu Cys Glu Ser Tyr Asn Arg Gln Phe Gly Arg Asp Tyr Arg Ser 145 150 155 160 Val Met Pro Thr Asn Leu Tyr Gly Pro Asn Asp Asn Phe His Pro Ser 165 170 175 Asn Ser His Val Ile Pro Ala Leu Leu Arg Arg Phe His Asp Ala Val 180 185 190 Glu Asn Asn Ser Pro Asn Val Val Val Trp Gly Ser Gly Thr Pro Lys 195 200 205 Arg Glu Phe Leu His Val Asp Asp Met Ala Ser Ala Ser Ile Tyr Val 210 215 220 Met Glu Met Pro Tyr Asp Ile Trp Gln Lys Asn Thr Lys Val Met Leu 225 230 235 240 Ser His Ile Asn Ile Gly Thr Gly Ile Asp Cys Thr Ile Cys Glu Leu 245 250 255 Ala Glu Thr Ile Ala Lys Val Val Gly Tyr Lys Gly His Ile Thr Phe 260 265 270 Asp Thr Thr Lys Pro Asp Gly Ala Pro Arg Lys Leu Leu Asp Val Thr 275 280 285 Leu Leu His Gln Leu Gly Trp Asn His Lys Ile Thr Leu His Lys Gly 290 295 300 Leu Glu Asn Thr Tyr Asn Trp Phe Leu Glu Asn Gln Leu Gln Tyr Arg 305 310 315 320 Gly * <210> 1267 <211> 373 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6387..7505) <400> 1267 Met Thr Lys Val Ala Leu Ile Thr Gly Val Thr Gly Gln Asp Gly Ser 1 5 10 15 Tyr Leu Ala Glu Phe Leu Leu Asp Lys Gly Tyr Glu Val His Gly Ile 20 25 30 Lys Arg Arg Ala Ser Ser Phe Asn Thr Glu Arg Ile Asp His Ile Tyr 35 40 45 Gln Asp Pro His Gly Ser Asn Pro Asn Phe His Leu His Tyr Gly Asp 50 55 60 Leu Thr Asp Ser Ser Asn Leu Thr Arg Ile Leu Lys Glu Val Gln Pro 65 70 75 80 Asp Glu Val Tyr Asn Leu Ala Ala Met Ser His Val Ala Val Ser Phe 85 90 95 Glu Ser Pro Glu Tyr Thr Ala Asp Val Asp Ala Ile Gly Thr Leu Arg 100 105 110 Leu Leu Glu Ala Ile Arg Phe Leu Gly Leu Glu Asn Lys Thr Arg Phe 115 120 125 Tyr Gln Ala Ser Thr Ser Glu Leu Tyr Gly Leu Val Gln Glu Ile Pro 130 135 140 Gln Lys Glu Ser Thr Pro Phe Tyr Pro Arg Ser Pro Tyr Ala Val Ala 145 150 155 160 Lys Leu Tyr Ala Tyr Trp Ile Thr Val Asn Tyr Arg Glu Ser Tyr Gly 165 170 175 Ile Tyr Ala Cys Asn Gly Ile Leu Phe Asn His Glu Ser Pro Arg Arg 180 185 190 Gly Glu Thr Phe Val Thr Arg Lys Ile Thr Arg Gly Leu Ala Asn Ile 195 200 205 Ala Gln Gly Leu Glu Ser Cys Leu Tyr Leu Gly Asn Met Asp Ser Leu 210 215 220 Arg Asp Trp Gly His Ala Lys Asp Tyr Val Arg Met Gln Trp Leu Met 225 230 235 240 Leu Gln Gln Glu Gln Pro Glu Asp Phe Val Ile Ala Thr Gly Val Gln 245 250 255 Tyr Ser Val Arg Gln Phe Val Glu Met Ala Ala Ala Gln Leu Gly Ile 260 265 270 Lys Met Ser Phe Val Gly Lys Gly Ile Glu Glu Lys Gly Ile Val Asp 275 280 285 Ser Val Glu Gly Gln Asp Ala Pro Gly Val Lys Pro Gly Asp Val Ile 290 295 300 Val Ala Val Asp Pro Arg Tyr Phe Arg Pro Ala Glu Val Asp Thr Leu 305 310 315 320 Leu Gly Asp Pro Ser Lys Ala Asn Leu Lys Leu Gly Trp Arg Pro Glu 325 330 335 Ile Thr Leu Ala Glu Met Ile Ser Glu Met Val Ala Lys Asp Leu Glu 340 345 350 Ala Ala Lys Lys His Ser Leu Leu Lys Ser His Gly Phe Ser Val Ser 355 360 365 Leu Ala Leu Glu * 370 <210> 1268 <211> 405 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7525..8739) <400> 1268 Met Lys Ile Ala Leu Asn Ser Asp Gly Phe Tyr Glu Trp Gly Gly Gly 1 5 10 15 Ile Asp Phe Ile Lys Tyr Ile Leu Ser Ile Leu Glu Thr Lys Pro Glu 20 25 30 Ile Cys Ile Asp Ile Leu Leu Pro Arg Asn Asp Ile His Ser Leu Ile 35 40 45 Arg Glu Lys Ala Phe Pro Phe Lys Ser Ile Leu Lys Ala Ile Leu Lys 50 55 60 Arg Glu Arg Pro Arg Trp Ile Ser Leu Asn Arg Phe Asn Glu Gln Tyr 65 70 75 80 Tyr Arg Asp Ala Phe Thr Gln Asn Asn Ile Glu Thr Asn Leu Thr Phe 85 90 95 Ile Lys Ser Lys Ser Ser Ala Phe Tyr Ser Tyr Phe Asp Ser Ser Asp 100 105 110 Cys Asp Val Ile Leu Pro Cys Met Arg Val Pro Ser Gly Asn Leu Asn 115 120 125 Lys Lys Ala Trp Ile Gly Tyr Ile Tyr Asp Phe Gln His Cys Tyr Tyr 130 135 140 Pro Ser Phe Phe Ser Lys Arg Glu Ile Asp Gln Arg Asn Val Phe Phe 145 150 155 160 Lys Leu Met Leu Asn Cys Ala Asn Asn Ile Ile Val Asn Ala His Ser 165 170 175 Val Ile Thr Asp Ala Asn Lys Tyr Val Gly Asn Tyr Ser Ala Lys Leu 180 185 190 His Ser Leu Pro Phe Ser Pro Cys Pro Gln Leu Lys Trp Phe Ala Asp 195 200 205 Tyr Ser Gly Asn Ile Ala Lys Tyr Asn Ile Asp Lys Asp Tyr Phe Ile 210 215 220 Ile Cys Asn Gln Phe Trp Lys His Lys Asp His Ala Thr Ala Phe Arg 225 230 235 240 Ala Phe Lys Ile Tyr Thr Glu Tyr Asn Pro Asp Val Tyr Leu Val Cys 245 250 255 Thr Gly Ala Thr Gln Asp Tyr Arg Phe Pro Gly Tyr Phe Asn Glu Leu 260 265 270 Met Val Leu Ala Lys Lys Leu Gly Ile Glu Ser Lys Ile Lys Ile Leu 275 280 285 Gly His Ile Pro Lys Leu Glu Gln Ile Glu Leu Ile Lys Asn Cys Ile 290 295 300 Ala Val Ile Gln Pro Thr Leu Phe Glu Gly Gly Pro Gly Gly Gly Val 305 310 315 320 Thr Phe Asp Ala Ile Ala Leu Gly Lys Lys Val Ile Leu Ser Asp Ile 325 330 335 Asp Val Asn Lys Glu Val Asn Cys Gly Asp Val Tyr Phe Phe Gln Ala 340 345 350 Lys Asn His Tyr Ser Leu Asn Asp Ala Met Val Lys Ala Asp Glu Ser 355 360 365 Lys Ile Phe Tyr Glu Pro Thr Thr Leu Ile Glu Leu Gly Leu Lys Arg 370 375 380 Arg Asn Ala Cys Ala Asp Phe Leu Leu Asp Val Val Lys Gln Glu Ile 385 390 395 400 Glu Ser Arg Ser * <210> 1269 <211> 367 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8764..9864) <400> 1269 Met Lys Met Lys Tyr Ile Pro Val Tyr Gln Pro Ser Leu Thr Gly Lys 1 5 10 15 Glu Lys Glu Tyr Val Asn Glu Cys Leu Asp Ser Thr Trp Ile Ser Ser 20 25 30 Lys Gly Asn Tyr Ile Gln Lys Phe Glu Asn Lys Phe Ala Glu Gln Asn 35 40 45 His Val Gln Tyr Ala Thr Thr Val Ser Asn Gly Thr Val Ala Leu His 50 55 60 Leu Ala Leu Leu Ala Leu Gly Ile Ser Glu Gly Asp Glu Val Ile Val 65 70 75 80 Pro Thr Leu Thr Tyr Ile Ala Ser Val Asn Ala Ile Lys Tyr Thr Gly 85 90 95 Ala Thr Pro Ile Phe Val Asp Ser Asp Asn Glu Thr Trp Gln Met Ser 100 105 110 Val Ser Asp Ile Glu Gln Lys Ile Thr Asn Lys Thr Lys Ala Ile Met 115 120 125 Cys Val His Leu Tyr Gly His Pro Cys Asp Met Glu Gln Ile Val Glu 130 135 140 Leu Ala Lys Ser Arg Asn Leu Phe Val Ile Glu Asp Cys Ala Glu Ala 145 150 155 160 Phe Gly Ser Lys Tyr Lys Gly Lys Tyr Val Gly Thr Phe Gly Asp Ile 165 170 175 Ser Thr Phe Ser Phe Phe Gly Asn Lys Thr Ile Thr Thr Gly Glu Gly 180 185 190 Gly Met Val Val Thr Asn Asp Lys Thr Leu Tyr Asp Arg Cys Leu His 195 200 205 Phe Lys Gly Gln Gly Leu Ala Val His Arg Gln Tyr Trp His Asp Val 210 215 220 Ile Gly Tyr Asn Tyr Arg Met Thr Asn Ile Cys Ala Ala Ile Gly Leu 225 230 235 240 Ala Gln Leu Glu Gln Ala Asp Asp Phe Ile Ser Arg Lys Arg Glu Ile 245 250 255 Ala Asp Ile Tyr Lys Lys Asn Ile Asn Ser Leu Val Gln Val His Lys 260 265 270 Glu Ser Lys Asp Val Phe His Thr Tyr Trp Met Val Ser Ile Leu Thr 275 280 285 Arg Thr Ala Glu Glu Arg Glu Glu Leu Arg Asn His Leu Ala Asp Lys 290 295 300 Leu Ile Glu Thr Arg Pro Val Phe Tyr Pro Val His Thr Met Pro Met 305 310 315 320 Tyr Ser Glu Lys Tyr Gln Lys His Pro Ile Ala Glu Asp Leu Gly Trp 325 330 335 Arg Gly Ile Asn Leu Pro Ser Phe Pro Ser Leu Ser Asn Glu Gln Val 340 345 350 Ile Tyr Ile Cys Glu Ser Ile Asn Glu Phe Tyr Ser Asp Lys * 355 360 365 <210> 1270 <211> 462 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9861..11246) <400> 1270 Met Asn Lys Ile Lys Lys Ile Leu Lys Phe Cys Thr Leu Lys Lys Tyr 1 5 10 15 Asp Thr Ser Ser Ala Leu Gly Arg Glu Gln Glu Arg Tyr Arg Ile Ile 20 25 30 Ser Leu Ser Val Ile Ser Ser Leu Ile Ser Lys Ile Leu Ser Leu Leu 35 40 45 Ser Leu Ile Leu Thr Val Ser Leu Thr Leu Pro Tyr Leu Gly Gln Glu 50 55 60 Arg Phe Gly Val Trp Met Thr Ile Thr Ser Leu Gly Ala Ala Leu Thr 65 70 75 80 Phe Leu Asp Leu Gly Ile Gly Asn Ala Leu Thr Asn Arg Ile Ala His 85 90 95 Ser Phe Ala Cys Gly Lys Asn Leu Lys Met Ser Arg Gln Ile Ser Gly 100 105 110 Gly Leu Thr Leu Leu Ala Gly Leu Ser Phe Val Ile Thr Ala Ile Cys 115 120 125 Tyr Ile Thr Ser Gly Met Ile Asp Trp Gln Leu Val Ile Lys Gly Ile 130 135 140 Asn Glu Asn Val Tyr Ala Glu Leu Gln His Ser Ile Lys Val Phe Val 145 150 155 160 Ile Ile Phe Gly Leu Gly Ile Tyr Ser Asn Gly Val Gln Lys Val Tyr 165 170 175 Met Gly Ile Gln Lys Ala Tyr Ile Ser Asn Ile Val Asn Ala Ile Phe 180 185 190 Ile Leu Leu Ser Ile Ile Thr Leu Val Ile Ser Ser Lys Leu His Ala 195 200 205 Gly Leu Pro Val Leu Ile Val Ser Thr Leu Gly Ile Gln Tyr Ile Ser 210 215 220 Gly Ile Tyr Leu Thr Ile Asn Leu Ile Ile Lys Arg Leu Ile Lys Phe 225 230 235 240 Thr Lys Val Asn Ile His Ala Lys Arg Glu Ala Pro Tyr Leu Ile Leu 245 250 255 Asn Gly Phe Phe Phe Phe Ile Leu Gln Leu Gly Thr Leu Ala Thr Trp 260 265 270 Ser Gly Asp Asn Phe Ile Ile Ser Ile Thr Leu Gly Val Thr Tyr Val 275 280 285 Ala Val Phe Ser Ile Thr Gln Arg Leu Phe Gln Ile Ser Thr Val Pro 290 295 300 Leu Thr Ile Tyr Asn Ile Pro Leu Trp Ala Ala Tyr Ala Asp Ala His 305 310 315 320 Ala Arg Asn Asp Thr Gln Phe Ile Lys Lys Thr Leu Arg Thr Ser Leu 325 330 335 Lys Ile Val Gly Ile Ser Ser Phe Leu Leu Ala Phe Ile Leu Val Val 340 345 350 Phe Gly Ser Glu Val Val Asn Ile Trp Thr Glu Gly Lys Ile Gln Val 355 360 365 Pro Arg Thr Phe Ile Ile Ala Tyr Ala Leu Trp Ser Val Ile Asp Ala 370 375 380 Phe Ser Asn Thr Phe Ala Ser Phe Leu Asn Gly Leu Asn Ile Val Lys 385 390 395 400 Gln Gln Met Leu Ala Val Val Thr Leu Ile Leu Ile Ala Ile Pro Ala 405 410 415 Lys Tyr Ile Ile Val Ser His Phe Gly Leu Thr Val Met Leu Tyr Cys 420 425 430 Phe Ile Phe Ile Tyr Ile Val Asn Tyr Phe Ile Trp Tyr Lys Cys Ser 435 440 445 Phe Lys Lys His Ile Asp Arg Gln Leu Asn Ile Arg Gly * 450 455 460 <210> 1271 <211> 249 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11239..11985) <400> 1271 Met Lys Ile Ser Val Ile Thr Val Thr Tyr Asn Asn Ala Glu Gly Leu 1 5 10 15 Glu Lys Thr Leu Ser Ser Leu Ser Ile Leu Lys Ile Lys Pro Phe Glu 20 25 30 Ile Ile Ile Val Asp Gly Gly Ser Thr Asp Gly Thr Asn Arg Val Ile 35 40 45 Ser Arg Phe Thr Ser Met Asn Ile Thr His Val Tyr Glu Lys Asp Glu 50 55 60 Gly Ile Tyr Asp Ala Met Asn Lys Gly Arg Met Leu Ala Lys Gly Asp 65 70 75 80 Leu Ile His Tyr Leu Asn Ala Gly Asp Ser Val Ile Gly Asp Ile Tyr 85 90 95 Lys Asn Ile Lys Glu Pro Cys Leu Ile Lys Val Gly Leu Phe Glu Asn 100 105 110 Asp Lys Leu Leu Gly Phe Ser Ser Ile Thr His Ser Asn Thr Gly Tyr 115 120 125 Cys His Gln Gly Val Ile Phe Pro Lys Asn His Ser Glu Tyr Asp Leu 130 135 140 Arg Tyr Lys Ile Cys Ala Asp Tyr Lys Leu Ile Gln Glu Val Phe Pro 145 150 155 160 Glu Gly Leu Arg Ser Leu Ser Leu Ile Thr Ser Gly Tyr Val Lys Tyr 165 170 175 Asp Met Gly Gly Val Ser Ser Lys Lys Arg Ile Leu Arg Asp Lys Glu 180 185 190 Leu Ala Lys Ile Met Phe Glu Lys Asn Lys Lys Asn Leu Ile Lys Phe 195 200 205 Ile Pro Ile Ser Ile Ile Lys Ile Leu Phe Pro Glu Arg Leu Arg Arg 210 215 220 Val Leu Arg Lys Met Gln Tyr Ile Cys Leu Thr Leu Phe Phe Met Lys 225 230 235 240 Asn Ser Ser Pro Tyr Asp Asn Glu * 245 <210> 1272 <211> 395 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11954..13138) <400> 1272 Val Lys Ser Ala Ala Lys Leu Ile Phe Leu Phe Leu Phe Thr Leu Tyr 1 5 10 15 Ser Leu Gln Leu Tyr Gly Val Ile Ile Asp Asp Arg Ile Thr Asn Phe 20 25 30 Asp Thr Lys Val Leu Thr Ser Ile Ile Ile Ile Phe Gln Ile Phe Phe 35 40 45 Val Leu Leu Phe Tyr Leu Thr Ile Ile Asn Glu Arg Lys Gln Gln Lys 50 55 60 Lys Phe Ile Val Asn Trp Glu Leu Lys Leu Ile Leu Val Phe Leu Phe 65 70 75 80 Val Thr Ile Glu Ile Ala Ala Val Val Leu Phe Leu Lys Glu Gly Ile 85 90 95 Pro Ile Phe Asp Asp Asp Pro Gly Gly Ala Lys Leu Arg Ile Ala Glu 100 105 110 Gly Asn Gly Leu Tyr Ile Arg Tyr Ile Lys Tyr Phe Gly Asn Ile Val 115 120 125 Val Phe Ala Leu Ile Ile Leu Tyr Asp Glu His Lys Phe Lys Gln Arg 130 135 140 Thr Ile Ile Phe Val Tyr Phe Thr Thr Ile Ala Leu Phe Gly Tyr Arg 145 150 155 160 Ser Glu Leu Val Leu Leu Ile Leu Gln Tyr Ile Leu Ile Thr Asn Ile 165 170 175 Leu Ser Lys Asp Asn Arg Asn Pro Lys Ile Lys Arg Ile Ile Gly Tyr 180 185 190 Phe Leu Leu Val Gly Val Val Cys Ser Leu Phe Tyr Leu Ser Leu Gly 195 200 205 Gln Asp Gly Glu Gln Asn Asp Ser Tyr Asn Asn Met Leu Arg Ile Ile 210 215 220 Asn Arg Leu Thr Ile Glu Gln Val Glu Ser Val Pro Tyr Val Val Ser 225 230 235 240 Glu Ser Ile Lys Asn Asp Phe Phe Pro Thr Pro Glu Leu Glu Lys Glu 245 250 255 Leu Lys Ala Ile Ile Asn Arg Ile Gln Gly Ile Lys His Gln Asp Leu 260 265 270 Phe Tyr Gly Glu Arg Leu His Lys Gln Val Phe Gly Asp Met Gly Ala 275 280 285 Asn Phe Leu Ser Val Thr Thr Tyr Gly Ala Glu Leu Leu Val Phe Phe 290 295 300 Gly Phe Leu Cys Val Phe Ile Ile Pro Leu Gly Ile Tyr Ile Pro Phe 305 310 315 320 Tyr Leu Leu Lys Arg Met Lys Lys Thr His Ser Ser Ile Asn Cys Ala 325 330 335 Phe Tyr Ser Tyr Ile Ile Met Ile Leu Leu Gln Tyr Leu Val Ala Gly 340 345 350 Asn Ala Ser Ala Phe Phe Phe Gly Pro Phe Leu Ser Val Leu Ile Met 355 360 365 Cys Thr Pro Leu Ile Leu Leu His Asp Thr Leu Lys Arg Leu Ser Arg 370 375 380 Asn Glu Asn Ile Ser Tyr Asn Cys Asp Leu * 385 390 <210> 1273 <211> 261 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(13135..13917) <400> 1273 Met Asn Lys Glu Thr Val Ser Ile Ile Met Pro Val Tyr Asn Gly Ala 1 5 10 15 Lys Thr Ile Ile Ser Ser Val Glu Ser Ile Ile His Gln Ser Tyr Gln 20 25 30 Asp Phe Val Leu Tyr Ile Ile Asp Asp Cys Ser Thr Asp Asp Thr Phe 35 40 45 Ser Leu Ile Asn Ser Arg Tyr Lys Asn Asn Gln Lys Ile Arg Ile Leu 50 55 60 Arg Asn Lys Thr Asn Leu Gly Val Ala Glu Ser Arg Asn Tyr Gly Ile 65 70 75 80 Glu Met Ala Thr Gly Lys Tyr Ile Ser Phe Cys Asp Ala Asp Asp Leu 85 90 95 Trp His Glu Lys Lys Leu Glu Arg Gln Ile Glu Val Leu Asn Asn Glu 100 105 110 Cys Val Asp Val Val Cys Ser Asn Tyr Tyr Val Ile Asp Asn Lys Arg 115 120 125 Asn Ile Val Gly Glu Val Asn Ala Pro His Val Ile Asn Tyr Arg Lys 130 135 140 Met Leu Met Lys Asn Tyr Ile Gly Asn Leu Thr Gly Ile Tyr Asn Ala 145 150 155 160 Asn Lys Leu Gly Lys Phe Tyr Gln Lys Lys Ile Gly His Glu Asp Tyr 165 170 175 Leu Met Trp Leu Glu Ile Ile Asn Lys Thr Asn Gly Ala Ile Cys Ile 180 185 190 Gln Asp Asn Leu Ala Tyr Tyr Met Arg Ser Asn Asn Ser Leu Ser Gly 195 200 205 Asn Lys Ile Lys Ala Ala Lys Trp Thr Trp Ser Ile Tyr Arg Glu His 210 215 220 Leu His Leu Ser Phe Pro Lys Thr Leu Tyr Tyr Phe Leu Leu Tyr Ala 225 230 235 240 Ser Asn Gly Val Met Lys Lys Ile Thr His Ser Leu Leu Arg Arg Lys 245 250 255 Glu Thr Lys Lys * 260 <210> 1274 <211> 13878 <212> DNA <213> Escherichia coli O157:H7 <400> 1274 taaacggtta accacggtcg aaatctgact gcaggcttga ctgcatgacc acagccactg 60 tggattgccg caaccgaccg caagccacga ataagaacga cggcgaattt cgaatcgtta 120 cctgatgcac tggcttccca gcgtttgacc gtagcgttaa gtaaatcaac aaaagcgatg 180 ttcaccgctt ttcgtcaagt cgtgccattt gtcagccagg atcgggtctt taccccggat 240 attgcagcat cgcaaaaatt cttagaggga tatgctataa atcaaaaata aaatctttgt 300 tgattgttta tcataatatc cacagatatg ataaatgata tcaatttaat aattttcact 360 taatgtgatt ccggataatt cgaaaggcgc tgtgcttttc ggattattat tatctgatta 420 agatatttgt cacgccagcc ttactggttt ataaatgtca atcatgattc ttataaatta 480 tttattgctg ctttggttac cattacttcg taataagtaa tgtatttttg atggtttaaa 540 ctatttttaa gggacggcat tatgcgaggg aaaataccta aaacggaact gctggtgact 600 tttgaggtcg tcgcacgtca tgaaagttat accagagcgg cagaggagtt agcgttaacc 660 caaagtgcag tattcagaca agtaagtgcg ctggaggaat ttttacgtac tccgttattt 720 tcacactcta aaaaacgcat ttttcttaat gatacaggga agtattacct ggggatagta 780 aaagaaacat taaataagct ggaacgcgat accaatacca ttatgacctg gcagcctacg 840 gttcaggtta ttgaacttgc cgttaatcct acttttagta cccactggtt aatcccaaat 900 ttacatgaat tcacaaagtt acatcccgat attattgtta atattcattc tttagctaat 960 aacggcgatt ttcttaatcg ggagtacgat gctgtcatta tgcgcgaaaa tttttgcgcg 1020 ccctgggcgg aagtagaata tctctttgaa gaggagattt tgccggtatg cagcggcagt 1080 ttgcttgcaa tgtccgatca aaaactgtca gtggcagaac tgcttactga gttaccactt 1140 ctgcatcaaa gcacccgtat tactggctgg gaagagtggt ttgctttatc tggcgttagc 1200 agtccgctgg tcaacaacgg accacgtttc gatttgcttt caatgctgat tgccgccgtg 1260 cgctctaatc tcggcgtggc gctgttacca cgtttcgcta ttcaacatga tttggatagt 1320 ggcgatatgg tgattccctg tgatgtgcct attcgtaccg gtaatcgttt tattatgacg 1380 tggcaggaag agaagtctga ctcaccgcac ttgcagcaat ttcgtgaatg gttgctggcg 1440 aaatcggtcg taccgcagga gatgtaaaac ctgcgcctgg cgggatgcca ggcgcagtta 1500 ttaccagtcg atacccggct gggcctgaat gccgttatca aaagcatgtt tgacggggcg 1560 gatttcgctg accgtatctg ccatttttaa tatctgactg tggcaaccgc gtccggtgac 1620 aatgacactt tgttgtgccg ggcggttttg cagagaagcg atcacttctt cggtatccag 1680 ataatggtaa gccagcatat aggtcagctc atcaagcacc actaagtcgt aacgcttgtc 1740 agccagcatc cgtttgcttt ccgaccagac ctctttcgcc gcgtcgatat ccgcttgccg 1800 gttctgtgtc tcccaggtaa aaccggttcc cataatatga aactcaaccc ccagcggctg 1860 gagaaggttg tattcgccgt tgtcccattg ccccttgatg tactgcgcaa cccccaccgt 1920 tttgccatga cccaccgcgc gcgtcacagt accaaacgcg gcagtggatt tccctttgcc 1980 gttgccggtg aaaacaatca agatcccttt tttctctatc gccgccgcga cgcgcgtatc 2040 gacctgttcc ttcaatttct gttggcgctg cacatgccgt tcagttgaaa ttcgcgcttc 2100 cattcatttt ccttaatgtc ccgcagggca actggcgcag cggtgttgct gctcaaactg 2160 actaaagaaa ttattgcctt tatcatctac caggatgaat gcgggcagat tttccacttc 2220 catcatccac accgcttcca tacccagctc cgggtattcc aggcaacgca gacttttgac 2280 atattcttgc gccagtaacg cagctgcacc gccaatactt cccagattga agccgccatg 2340 tttgtgacag gcatcggtga cctgctggct gcggttacct ttcgataaca tcactagact 2400 gccgccagcc gcctggaagg tatcgatata accgtccatt cgaccgcccg tggttggacc 2460 cagtgaaccg caggccatgt tctccggtgt tttcgccggg ccagcgtaat agacaatatg 2520 atgcttcagg tactccggca tcggttcgcc gctatccagc cgcgctttta ttttggcgtg 2580 ggcgatatcg cgcgccacta cgatgggacc acttaacgac acgcgggtgc ctactggtaa 2640 tctggcgaga tcctgcatca cgtcacgcaa cggacggttt agatccagtt gtacatgttg 2700 cgcgtgattt tcttcccgca gtgaggctgg aatatattgc cccggattgt gttcgagttt 2760 ttccagccag ataccgtgtt tgttaatttt tgctttgata ttgcgatcgg cagaacagga 2820 gagcgccata gctatcgggc aagagccacc gtgacgcggc agacgaatga cgcgaatatc 2880 atgagcgaaa tatttacccc caaattgcgc accaatacca aattgctgac tggcctcgag 2940 caacactttt tccagctcaa tatcacggaa tgcttgtccc tgctcgtttc cgctggtggg 3000 caaattgtcg taatatttcg ttgaggccag cttggcaatt tttaaggttt gatcggctga 3060 aagccctccg acgacaaagg cgatgtggta aggcgggcag gcagcggtgc ccagcgattt 3120 cattttttcg attaaaaatg cggtcagttt ttctggttgc aataaggatt tggtttcctg 3180 ataaagcgcg gctttattgg cggagccgcc ccctttatta acacagagaa aatggtactc 3240 atcaccagcg acagcgctga tatcaatctg cgccgggaga ttggtttgcg tattgacttc 3300 ggtatacata tccagcggcg cattttgtga aaagcgcaga ttattttcct ggaaagtact 3360 gtaaatgcct ttacttaagg cttcggcgtc gttacctccg gtccatatct gttgcccttt 3420 actggcaaca atagttgcgg tgccggtatc ctgacagttg ggtaataccc cttttgctga 3480 gacttcagca ttacgtaata actgcaacgc aacgtattta tcattactgc tggcctgctg 3540 atcgttaaga atgctggcga cctgttgcaa atgagcggaa cgtaagaaaa aagaggcttc 3600 ataaaatgcc tgccgggcaa gcagcgttaa tgcttcagga gcgattttta tcacttcttc 3660 gccgtctaat tccgttactg taatatgttg atcgctaatt aatgtatatt ctgtaccgtc 3720 tttattttgt agaaacggtt cttgccagat aaatggtttg gacatatttc acttttcacc 3780 ttaaacgtta gtgttactta attgccgtct aacttcatga tccggcttat aaaaatgcgt 3840 agtcattggc ttctgattgc ttaagatccc cctcagggca gagcaacgtt cgattcattg 3900 ggttttaatg ctttaccccg acagccctcg ccgaaatgtt cgccttccca ccgactcacc 3960 atcgcagcgc ccattgcgtt gctcatgacg tttgtcgcgg aacgccccat atcaaggaac 4020 ggatcaacgc ccatcagcaa gatcagcccc gcttccggaa tattgaactg gttgagcgtg 4080 gcggcgataa ccaccattga ggcgcgtggt acgccagcca ttcctttcga ggtcaacatc 4140 aggatcaaca gcatggtgat ttgctcaccg atggataaat ggatattgca ggcctgggcg 4200 atgaaaactg tggcgaagga gcagtaggcc attgatccaa cgagattaaa tgagtagcca 4260 atgggtaaga caaagctggc aattttgggg gaaacgccaa attgctccag tttttcaagc 4320 gttcccggaa aagccgcttc agaactggat gtggtaaatg ccagcagggc gggttccgaa 4380 agggcgcggg tcaggcgtct gatgcagggg ccgacataaa cgatggccag accgataagc 4440 agtacccaaa gtaataacat ggtgaaataa aattcaccca taaagatccc ggcgctcacc 4500 ataactgcca gtcctcgttc agcaatcaat gctgaaatag cagcgaatac ggtcagggga 4560 gcgaagagca tgacgtagcc agtgagcttt aacatggcat gtgccagcga atctaaggcg 4620 tgaacgatgg cgctgccttt ctcgccaatc gccgtcaggc tacagccgag gaaaattgag 4680 aacaccacga tttgcaaaat ttcattgtgc gccatggcat cgacaatgct ggtggggaaa 4740 gcatgcgaaa taaatacttt tagcgtaaag ggttctgccg cgaccactcc ggtggtttcg 4800 gcaccgtgtg caacaaaatt aattcctgta cctggcatga agaaatttac cgttatcaag 4860 cctaaggcaa ttgacagcaa tgaggcgcaa ataaataaaa agagtgtttt agaaaaaata 4920 cgaccaaggg ctttggcatc gcccatttta gcaataccta ccaccagggt agagaccact 4980 aacggagcga taatcatttt tatcagtcgt aagaaaatcg tcgtgaatat cgatatttct 5040 tgcgcataga gttttgcggt ttccggtgaa gcagtgttat tgagcactac gccgataatc 5100 attccaagta ccagcgccaa aagaatcatc gtggttaaac ttattttctt cattttttcc 5160 tccatcaggt gcacggcgat aaatcagaat caggagaagt agatgcctga atagagattc 5220 aggcatctac ctgctattac aaccttacaa atagctgaag tgttgaactg caataagtga 5280 cgggatgtca gttggctaaa agtattcgga tttttacaaa tcgaaactca tatttaataa 5340 aggtgcatgt tgctgtgcac catagacatc attgtcacct acattcccgg agataatatc 5400 tcgtggcatg acgattttta ctgcgttaga aggatcaaac cagacaatac gatgaataaa 5460 gtcaggttca acatgatata agcgtgcaat cagttctggg gttaattgcc ctgatgattt 5520 aactcgctca tagttttctt tcgttttaaa taaaatatct aaaaccagtt cgtaaggtcc 5580 ggcatttttc gaacgaatga cttgcgccag tgagacaatt gactgtttca tgcctgaact 5640 ccttctggcg tcacctgttc aatatggaaa tcaaaacgca gagcgtcgtt ggcttcaatc 5700 aggtgatata tggaaaattc gtataccggc ccgccctgga tatcagaagg ggagaacggg 5760 aacgccagat tacctgcggt agcgatgcgg ttttcatagc cgtagtgcag catggtagag 5820 cgcaccagcg agcaaacgct gttggcaatt tcctgggtcg gtgcaactac atcaaggaca 5880 atccccagct catgcccggc agtttgcatc ggttcatggt ctcccatcac cccgtttttg 5940 ccgtacaggt ggaaattgat gcgaatgctg tcatcgtcga gcgacaggtt acgcgaaacg 6000 ctggttttga cttcatcgat gattttatcg atcccggcga tcataatcgg gtcgcgcgtt 6060 ccggcgatgg tcagacagcg gaagcccacc cgtcgtgcac cttccagttt cagggcatac 6120 ggcgtttctt catgcttaga accgctgacg tagacttcgc cgtcatttac tgctttaaat 6180 gtgcagcctt tcaggttcaa cacgccgcca ggtcctggca ggaagtaggg atcggatttc 6240 tcatacagtg tgtgtgcagc tgctgacgtt tcggtaaatt tacgcttcgg attaaatgtt 6300 ttcagcgtaa agccgttgtc atcaatgatg cccatcgcac agtcagagcc tgagccgggc 6360 gttgcggcga ttgccgcgca ttcaaggatt ttcccacaat gcagcgccag accttcatca 6420 aagccttgca tgatcgggag cgcagcaaag caggccgggt cgtaagcgcg cccgcccagc 6480 accacttgcg cgcgttcttt cagcgcccgc tggaagggtt cgatgcccat ttgcgcgacg 6540 atatacgtac tttcgtcaat cgcgtcgtgg gttaacggcg ggacaaaatc cagcgccgtg 6600 attttgccgt tatccagcgc ctggtggacg atggctttgt caacgtctgc cgggatcaac 6660 gccatcgaga acgagaggtg ctcttcccgg gcaatctcat gaattatttc tcggcaccac 6720 tccaggtgtg gtgcggcacc agaaccgcca gccgttccga tcaccaccgg tatattattt 6780 tgcacgcctg cggtgatcat atagcgcaga tcgcgcttga cccctgcgcg atcggtaaac 6840 ggtttgcctg ccccgaggta gtgggggcct ggatcggaag agcctgcatc aacggcgatc 6900 agatcgggcg attctgccat cgctttgcgg aagctctctt ccgggaatcc atacccgagg 6960 attgccgttg gcgataagac tttaaaagaa cgagccattt gttaatcctt agcctgcaac 7020 agcgcgatag tacgattcat ttcgttgaag acgatatcga ggccttcgtc aaagcccatc 7080 cctggtttta ccagcatacg catggggcga gcggcaaggg cgacgtggac acaggtgcgg 7140 gcactgacat cagtttcatt gcaggtgccg ccctggtacg cttccatgct gtggctgttg 7200 cagtaaagaa ccgcatcgac gatgttgtga atactgccca gatccggggt tttgatttgc 7260 accatgtgac aactggcagc atcagtgaaa tcaacaatat cctggtaggt gttacaccat 7320 tcatcggcca caattttcac gccggaaccg aggcgcgtca gctctttggt aatcgcggtc 7380 agcaggcgaa tttgatcggg cttgttaccg gcatcgaccg gcccttcgat gtagagcggc 7440 aggccttgcg cttctttttc caggctggcg atgtattgcg cacagcgaag cggatccata 7500 tcgaagatca gaccgatagt gccgtataca tcgatgtgca gggtagggtg gtagcgtgcg 7560 ctggtgcgct tgcttagaat gcgatccgac aaccagcgga catattcgcg cagtttttca 7620 cctttaaagc ccagcttctc ttcgacgtta ttaatcagcg catggggcag cacgtcgatg 7680 cctttaagga tcatcttatc gacggcgata tatcgatcgt cgccgctctg accaaataat 7740 ggaatggatt ccgccacgcg tggcaactgc cattcatcac agaccacttc agttttcaga 7800 cggccggttg ccagcgcggt agcatcaagc agcgcctgtg ataatccgta gcgcacggcg 7860 gtatgcagca agttgccgtc aatacgcaat ttgtcgaaga aacgggcatt cggcaggaaa 7920 gcatccacat cgcggcctac cagtaatggc ttgatatggt cgttgaggaa cggaataaag 7980 tgctctgcga ggaacagtgg atcgcgaccg cctgccccgg aatactgtac ggcagtacag 8040 tcacctacgg cgaccgcgcc gttttccaga atcaactgta ccgatacgca ctccccggcc 8100 tgacgtacgg cgttaaaccc ctgtgttact ggctccccgg tataaaaaaa gccgtcatga 8160 cccgctccgt tttttatcgc ctgctggtca tcgaaataga atgaggagta gccagcggtg 8220 aacagagcct gttttatttt cattatggtc ttcctattaa tttactgtgg gatacagcat 8280 tgatgtcatc tacaaccatc tggaatgtcg gttggcgtcc ttcacagcgt gcgcgttccg 8340 caacgtaatc gtggtggagg tcgagaatat cttttggcaa tggaacggct ccggcttcca 8400 gtacgcgtat cgcgccggtg ttgtcacgga ccggaagaat tttgcccgcg ttgcaggcgg 8460 ctggcgcaaa cggcacatcc agtacgcccg cttcaaatgc cagcaccgtt ccgcgcgcaa 8520 tatcaccatt acccagttcg aacactttat tcagtaccgc gcgaacctcg ctcttaatca 8580 gttcaatttc cagttcaacc gcagggcacg gcgggaattt ctgctcattg accatgttga 8640 gcatttggcg ggaggctttc agcccctgaa tgttggcagc ggcagtcggg ataccccagg 8700 cttcgtgcgg acttttggtg atgactttgg tggcaccaga catccccgcg acggctgcgc 8760 cccaggagat aatagcgaac gctttcgatt cgtcttccgg aaagccgccc atccactggt 8820 gaaacacggt actcaattca tagtcggtat agccatagct ctgaaaatat tcgtgtgcaa 8880 gttcacgcag agactggatc gccgcaacat cctgcgtcag gctgccgacc tggccataac 8940 caacggtgat agatttcaca ccctgttcca gcgccagcaa gccttcgatt atcgcgatag 9000 agtgcgagat aaacggcggg atcagcgtac ccgttagtgg gccaaacggt tcgcggttga 9060 tgcggatccc gtgttcttca tacatcccca ttaaacggtc gcagtactgc cagtcgcgga 9120 tcgatttttc cagcgttacg cgtttggcat acggaatgtt gtaggaaatg ccaccgcctt 9180 cataactggt aaagccgctg gccattgaga tttcagccag cagacgcgca tctggcgtgc 9240 cgtggcggat ctgtagcggt ttttgcaggg tttcggtgag gcgacggcaa gctgcgacac 9300 catggttaac taccggtaaa ccgttcagtt tagaggttcc ggcttcgatg gattttttaa 9360 tccctacagc cgcttcttcg taccgattca gacgggtata tgcatcgatg gtgcttggca 9420 gcagatcgca ctcttcttgt agtgttttca gcagttcgat gtgttcgtcc atcagcgcca 9480 cacctgcgcg cggttggcta agggttttac cttccttgtc tgctttcagc agcgcaagag 9540 agaaacgttt atgctcaggg atggtttgtt ggtatttaac gccatcttca aagttttcaa 9600 catccttgcc ggtttcccag gttttcagta cctgttgccg ctcggtcatg aattcgtcat 9660 gggttaattt cttatttcga agttccattg attgcagcct taattgttat agggttaagc 9720 attgaatact ggtgcgcgcg gcggccagcg gatcgactct ggcgacgttt gccagcagtg 9780 gtaatagccc ccgggaatcg cggtaatatt caaattcggt cggtaagaga atgcgtttac 9840 cgtcgtcgtt taactcgcgg tatttcaacc agtgatgcat atcgaactga ctggcacgcg 9900 agagccatcc gccggatccg acgactttac gcacggttgt caggtcacgt cccatctgta 9960 aatcgacatt gccgacgcag gtgcagacct cttttttggt gcccgcatgt ctttcggtgg 1002 0 cataacccac acacagtccg gccaggacgg tatcgaaata tttctcttct gcatttgcgg 1008 0 gtaagtagtc gggatgagcg actagatgac ggaggtaatg ataaaaagcg tccagctgtg 1014 0 cgggttgctg agcaaaattc acattgacta actctttcgc actttcacca accaccactg 1020 0 ccgagacgcg cattcccaga tcgccttcca ccgtccgttt tacgaagggt tccggtacgc 1026 0 cgtgtaaaac ggtgtcgggc gagagcgtgt tggcacaggc ggaataaaca tcggtggttg 1032 0 cgccgcccat gtcgatcagc atgaactctt tccagctgtg atcgacgtta ctgattgcct 1038 0 tgaccagttc aaagaccgtc catggtgtcg gcattggttc ttcgcctgtt ttatcaacaa 1044 0 tgacatccag ccctttccct ttaacgatgc gtttaaggaa tatgtcgcaa atagcctggc 1050 0 gtgcagctac agggttcgga tggtcaagat cgggcagaac gttgtcgaca atggtcaggt 1056 0 ctttatgccc gaggatctcc tgcacctcgt cctgaatatc ccggtttccg gcataaataa 1062 0 tggcgcagtc gagtttggat tctgccagca cacgggcgtt attcagtccg tagctttctt 1068 0 ctccgccgtc ggtgccgccg gtgaacaaga gaatatcggg ctgcgtttct tccagtgcct 1074 0 ggatatcacg gcggttcagc ttgtaggcgt aatattgcgc aattttagca cccgcagagt 1080 0 gagcggttac tttcgcggtt tccagggtga tagaaggcac caatcccatt gcggcaaccg 1086 0 ccagcccacc tttggcagag gaggaatact tcaatgcaac ctcaccgctg tttaacaggg 1092 0 ggagggcatt atctacgttt aacacctggt tcaggctgga gaaaaacccc ttcgccagat 1098 0 gatgggtggt ggttggggtc agtacgtggt taaccaacgt taacgcgtcc ccctcccggg 1104 0 taaagagggc tgctttggtc cacgtcgatc caatatcgac agagacgatt tgcatcagat 1110 0 agcctcttca agaatacgag tatcaacgtc atgacgttgg ttgatatcgt gggccatcag 1116 0 ctggcaaaca tcttctaagt catgacttgg ggcaaagacg cgatcaaatc ccatctcttt 1122 0 gaatttggtt tccacgtcag cgaagtcatg ttttccgacc accaggttac cgcccacata 1128 0 gagcaggatg tcccccagtc cacgctcgat gcagcgttcg cgcatgccca gacagtcgat 1134 0 atcgccatgc ccatagatag aggagacgac aatcgcgtca gcgccagttt caatggcagc 1140 0 atcaatatat tcgtcctggc tgaccattac gcccagatta atgactctga agtcgtggtt 1146 0 gctaaaaacg cggtccagaa ctttattgcc tactgcatgg cagtccgcgc caataacgcc 1152 0 aatcacaagt gttgctttct tcatgggtaa tcctttgtaa gacagagagt aaaataagtt 1158 0 acacacgtcg tatttatggc cgttcataac ggcacaggtt taatatcaca ggagtgtctt 1164 0 tatctgaccg taatgttgca attgatctat tttcaaaatg tctttcggga aatgattgtt 1170 0 tgaagtgtgt ttttaaattt ccatgttaat tcagtgtgtt atgtcaacta atgtcatgag 1176 0 tgttaaattt ttaaaattaa cttgatttaa tgtattgaga taattgtgat ctacttctaa 1182 0 tttgcatttt tgtgacgtgg ttttagccat gagtaaatgc atttcataag atttaagtcg 1188 0 aatttcactg caattcatct ctgcttaatg taaaaataat gttgaaaata acaaatggtt 1194 0 aatgattcat gcgaattatg accttagtta gctcttttaa tttttcgtaa aaaagagagg 1200 0 tacatgaagg tgctatcagt atgagtaacg ttaatcaaag gttttattac gtctggcaat 1206 0 aacgcaggcc atttttcgcg acagggtgga tttaatcagt ataatcctca tacaatagtt 1212 0 cacgattaac tgaaccgtta acggggattt ggtgttgaaa tttagaaatg gcggagtcaa 1218 0 ttaatgaaga caatatcgaa aaaatgactg tgtcagaatt aatttcaatt aatccttctc 1224 0 gttgttgacc aaaaaagata tttatcttga tttcatttgt actacggcaa tcaatatgta 1230 0 gtaatttttg atcgctgaga ttttctgttt cataaatgtt tttggcgaga gtcgggtgta 1236 0 ttgatgccag acatctgctc agataagcca tatcctttag ggaacacccc gctgagtaga 1242 0 ggatgtcaga gaatttttgt gtgtcaactg ttgtctctga agcgtatgtt gcattgactg 1248 0 gaagggtatt gaaagagatc tgagatggta tcattattta aatctttccg tgagtaataa 1254 0 aaattaatcc ccaggcattg tttagcaata tttgccatag gggatatata gaaaattaaa 1260 0 gtattttatt ggcttcggtt aactgatcta taaccagtgc cagattggta aacattttga 1266 0 aaaagcgata ctggctcgga atatctcttt caaagacgaa acattcaatg tcattgtttg 1272 0 aaaaataaag gactagtgtt gctgattcgt cagggaaaac atggaaatgt atctggttac 1278 0 cagaaggagg atagtccaga agaagggtat ctttgcccgt cacatacctg ttgttgtcgt 1284 0 ggacgctacg ctcacacttc atcagaggtg tcaggatact catgtattca tctgatgtta 1290 0 atttattaaa atcatcattc attttaaaga aacgataaag taacagtaca tcctcttgcg 1296 0 taaccggttc gtttgttttt agagggaaat aagcgggaac cagaagatga ggttctaatc 1302 0 tattttgttg agcgctataa ctgaatttga acataaattc cggatcgctc atcaattgag 1308 0 cgacataatt atgcctggct tcgaaaattt taatttttat caggttaaat aagtctgttt 1314 0 cgtcatcctg tattacaaga cattggccat agcagccagg ttttttttca ttataagcag 1320 0 aaacggttat tctgtcagag gtgtcaacgt tatattcaaa agccagatag tgactttctt 1326 0 catcgcgatt tgtttccaga ttatttaaat tcatcacatg aagtgtttgc aatgctgatt 1332 0 caatgagctg ttgactctct gaggtaaatg tttcgcgctg cgttgtataa agtgtatcaa 1338 0 ttccaacgac tatccgatgt gggtcaagga tggcggcaat catctttatt acctgcacag 1344 0 tcacgggtga tgtcattgat tctttatctg tttttagaga atcattagat ggccaacctg 1350 0 agaagcgatt gacagccgaa ccgatattat caggactcat agcagcaacc tcattgtaat 1356 0 caagcgaggc gctgagcgta ctcggctata gaaaaactaa cttgcaaaaa tcgctcattt 1362 0 ttcatttatc aggcgaaagt ggcctctgtt cactcagaaa caatcactcc cggtaagtca 1368 0 tacctgtttc atcgatacat ttaagtgatt attactaatg aaacaataac ataacgggct 1374 0 tacggtcggt gctcataaag gcaacaatca attaactttg ataaaaatat gttatgtaaa 1380 0 atagcaacaa attggctact ctaatcaatt ggtattataa aaagtggata aggcggttct 1386 0 gttaaataaa atactggt 1387 8 <210> 1275 <211> 302 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(562..1467) <400> 1275 Met Arg Gly Lys Ile Pro Lys Thr Glu Leu Leu Val Thr Phe Glu Val 1 5 10 15 Val Ala Arg His Glu Ser Tyr Thr Arg Ala Ala Glu Glu Leu Ala Leu 20 25 30 Thr Gln Ser Ala Val Phe Arg Gln Val Ser Ala Leu Glu Glu Phe Leu 35 40 45 Arg Thr Pro Leu Phe Ser His Ser Lys Lys Arg Ile Phe Leu Asn Asp 50 55 60 Thr Gly Lys Tyr Tyr Leu Gly Ile Val Lys Glu Thr Leu Asn Lys Leu 65 70 75 80 Glu Arg Asp Thr Asn Thr Ile Met Thr Trp Gln Pro Thr Val Gln Val 85 90 95 Ile Glu Leu Ala Val Asn Pro Thr Phe Ser Thr His Trp Leu Ile Pro 100 105 110 Asn Leu His Glu Phe Thr Lys Leu His Pro Asp Ile Ile Val Asn Ile 115 120 125 His Ser Leu Ala Asn Asn Gly Asp Phe Leu Asn Arg Glu Tyr Asp Ala 130 135 140 Val Ile Met Arg Glu Asn Phe Cys Ala Pro Trp Ala Glu Val Glu Tyr 145 150 155 160 Leu Phe Glu Glu Glu Ile Leu Pro Val Cys Ser Gly Ser Leu Leu Ala 165 170 175 Met Ser Asp Gln Lys Leu Ser Val Ala Glu Leu Leu Thr Glu Leu Pro 180 185 190 Leu Leu His Gln Ser Thr Arg Ile Thr Gly Trp Glu Glu Trp Phe Ala 195 200 205 Leu Ser Gly Val Ser Ser Pro Leu Val Asn Asn Gly Pro Arg Phe Asp 210 215 220 Leu Leu Ser Met Leu Ile Ala Ala Val Arg Ser Asn Leu Gly Val Ala 225 230 235 240 Leu Leu Pro Arg Phe Ala Ile Gln His Asp Leu Asp Ser Gly Asp Met 245 250 255 Val Ile Pro Cys Asp Val Pro Ile Arg Thr Gly Asn Arg Phe Ile Met 260 265 270 Thr Trp Gln Glu Glu Lys Ser Asp Ser Pro His Leu Gln Gln Phe Arg 275 280 285 Glu Trp Leu Leu Ala Lys Ser Val Val Pro Gln Glu Met * 290 295 300 <210> 1276 <211> 201 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1501..2103) <400> 1276 Met Glu Ala Arg Ile Ser Thr Glu Arg His Val Gln Arg Gln Gln Lys 1 5 10 15 Leu Lys Glu Gln Val Asp Thr Arg Val Ala Ala Ala Ile Glu Lys Lys 20 25 30 Gly Ile Leu Ile Val Phe Thr Gly Asn Gly Lys Gly Lys Ser Thr Ala 35 40 45 Ala Phe Gly Thr Val Thr Arg Ala Val Gly His Gly Lys Thr Val Gly 50 55 60 Val Ala Gln Tyr Ile Lys Gly Gln Trp Asp Asn Gly Glu Tyr Asn Leu 65 70 75 80 Leu Gln Pro Leu Gly Val Glu Phe His Ile Met Gly Thr Gly Phe Thr 85 90 95 Trp Glu Thr Gln Asn Arg Gln Ala Asp Ile Asp Ala Ala Lys Glu Val 100 105 110 Trp Ser Glu Ser Lys Arg Met Leu Ala Asp Lys Arg Tyr Asp Leu Val 115 120 125 Val Leu Asp Glu Leu Thr Tyr Met Leu Ala Tyr His Tyr Leu Asp Thr 130 135 140 Glu Glu Val Ile Ala Ser Leu Gln Asn Arg Pro Ala Gln Gln Ser Val 145 150 155 160 Ile Val Thr Gly Arg Gly Cys His Ser Gln Ile Leu Lys Met Ala Asp 165 170 175 Thr Val Ser Glu Ile Arg Pro Val Lys His Ala Phe Asp Asn Gly Ile 180 185 190 Gln Ala Gln Pro Gly Ile Asp Trp * 195 200 <210> 1277 <211> 551 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2113..3765) <400> 1277 Met Ser Lys Pro Phe Ile Trp Gln Glu Pro Phe Leu Gln Asn Lys Asp 1 5 10 15 Gly Thr Glu Tyr Thr Leu Ile Ser Asp Gln His Ile Thr Val Thr Glu 20 25 30 Leu Asp Gly Glu Glu Val Ile Lys Ile Ala Pro Glu Ala Leu Thr Leu 35 40 45 Leu Ala Arg Gln Ala Phe Tyr Glu Ala Ser Phe Phe Leu Arg Ser Ala 50 55 60 His Leu Gln Gln Val Ala Ser Ile Leu Asn Asp Gln Gln Ala Ser Ser 65 70 75 80 Asn Asp Lys Tyr Val Ala Leu Gln Leu Leu Arg Asn Ala Glu Val Ser 85 90 95 Ala Lys Gly Val Leu Pro Asn Cys Gln Asp Thr Gly Thr Ala Thr Ile 100 105 110 Val Ala Ser Lys Gly Gln Gln Ile Trp Thr Gly Gly Asn Asp Ala Glu 115 120 125 Ala Leu Ser Lys Gly Ile Tyr Ser Thr Phe Gln Glu Asn Asn Leu Arg 130 135 140 Phe Ser Gln Asn Ala Pro Leu Asp Met Tyr Thr Glu Val Asn Thr Gln 145 150 155 160 Thr Asn Leu Pro Ala Gln Ile Asp Ile Ser Ala Val Ala Gly Asp Glu 165 170 175 Tyr His Phe Leu Cys Val Asn Lys Gly Gly Gly Ser Ala Asn Lys Ala 180 185 190 Ala Leu Tyr Gln Glu Thr Lys Ser Leu Leu Gln Pro Glu Lys Leu Thr 195 200 205 Ala Phe Leu Ile Glu Lys Met Lys Ser Leu Gly Thr Ala Ala Cys Pro 210 215 220 Pro Tyr His Ile Ala Phe Val Val Gly Gly Leu Ser Ala Asp Gln Thr 225 230 235 240 Leu Lys Ile Ala Lys Leu Ala Ser Thr Lys Tyr Tyr Asp Asn Leu Pro 245 250 255 Thr Ser Gly Asn Glu Gln Gly Gln Ala Phe Arg Asp Ile Glu Leu Glu 260 265 270 Lys Val Leu Leu Glu Ala Ser Gln Gln Phe Gly Ile Gly Ala Gln Phe 275 280 285 Gly Gly Lys Tyr Phe Ala His Asp Ile Arg Val Ile Arg Leu Pro Arg 290 295 300 His Gly Gly Ser Cys Pro Ile Ala Met Ala Leu Ser Cys Ser Ala Asp 305 310 315 320 Arg Asn Ile Lys Ala Lys Ile Asn Lys His Gly Ile Trp Leu Glu Lys 325 330 335 Leu Glu His Asn Pro Gly Gln Tyr Ile Pro Ala Ser Leu Arg Glu Glu 340 345 350 Asn His Ala Gln His Val Gln Leu Asp Leu Asn Arg Pro Leu Arg Asp 355 360 365 Val Met Gln Asp Leu Ala Arg Leu Pro Val Gly Thr Arg Val Ser Leu 370 375 380 Ser Gly Pro Ile Val Val Ala Arg Asp Ile Ala His Ala Lys Ile Lys 385 390 395 400 Ala Arg Leu Asp Ser Gly Glu Pro Met Pro Glu Tyr Leu Lys His His 405 410 415 Ile Val Tyr Tyr Ala Gly Pro Ala Lys Thr Pro Glu Asn Met Ala Cys 420 425 430 Gly Ser Leu Gly Pro Thr Thr Gly Gly Arg Met Asp Gly Tyr Ile Asp 435 440 445 Thr Phe Gln Ala Ala Gly Gly Ser Leu Val Met Leu Ser Lys Gly Asn 450 455 460 Arg Ser Gln Gln Val Thr Asp Ala Cys His Lys His Gly Gly Phe Asn 465 470 475 480 Leu Gly Ser Ile Gly Gly Ala Ala Ala Leu Leu Ala Gln Glu Tyr Val 485 490 495 Lys Ser Leu Arg Cys Leu Glu Tyr Pro Glu Leu Gly Met Glu Ala Val 500 505 510 Trp Met Met Glu Val Glu Asn Leu Pro Ala Phe Ile Leu Val Asp Asp 515 520 525 Lys Gly Asn Asn Phe Phe Ser Gln Phe Glu Gln Gln His Arg Cys Ala 530 535 540 Ser Cys Pro Ala Gly His * 545 550 <210> 1278 <211> 427 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3873..5153) <400> 1278 Met Lys Lys Ile Ser Leu Thr Thr Met Ile Leu Leu Ala Leu Val Leu 1 5 10 15 Gly Met Ile Ile Gly Val Val Leu Asn Asn Thr Ala Ser Pro Glu Thr 20 25 30 Ala Lys Leu Tyr Ala Gln Glu Ile Ser Ile Phe Thr Thr Ile Phe Leu 35 40 45 Arg Leu Ile Lys Met Ile Ile Ala Pro Leu Val Val Ser Thr Leu Val 50 55 60 Val Gly Ile Ala Lys Met Gly Asp Ala Lys Ala Leu Gly Arg Ile Phe 65 70 75 80 Ser Lys Thr Leu Phe Leu Phe Ile Cys Ala Ser Leu Leu Ser Ile Ala 85 90 95 Leu Gly Leu Ile Thr Val Asn Phe Phe Met Pro Gly Thr Gly Ile Asn 100 105 110 Phe Val Ala His Gly Ala Glu Thr Thr Gly Val Val Ala Ala Glu Pro 115 120 125 Phe Thr Leu Lys Val Phe Ile Ser His Ala Phe Pro Thr Ser Ile Val 130 135 140 Asp Ala Met Ala His Asn Glu Ile Leu Gln Ile Val Val Phe Ser Ile 145 150 155 160 Phe Leu Gly Cys Ser Leu Thr Ala Ile Gly Glu Lys Gly Ser Ala Ile 165 170 175 Val His Ala Leu Asp Ser Leu Ala His Ala Met Leu Lys Leu Thr Gly 180 185 190 Tyr Val Met Leu Phe Ala Pro Leu Thr Val Phe Ala Ala Ile Ser Ala 195 200 205 Leu Ile Ala Glu Arg Gly Leu Ala Val Met Val Ser Ala Gly Ile Phe 210 215 220 Met Gly Glu Phe Tyr Phe Thr Met Leu Leu Leu Trp Val Leu Leu Ile 225 230 235 240 Gly Leu Ala Ile Val Tyr Val Gly Pro Cys Ile Arg Arg Leu Thr Arg 245 250 255 Ala Leu Ser Glu Pro Ala Leu Leu Ala Phe Thr Thr Ser Ser Ser Glu 260 265 270 Ala Ala Phe Pro Gly Thr Leu Glu Lys Leu Glu Gln Phe Gly Val Ser 275 280 285 Pro Lys Ile Ala Ser Phe Val Leu Pro Ile Gly Tyr Ser Phe Asn Leu 290 295 300 Val Gly Ser Met Ala Tyr Cys Ser Phe Ala Thr Val Phe Ile Ala Gln 305 310 315 320 Ala Cys Asn Ile His Leu Ser Ile Gly Glu Gln Ile Thr Met Leu Leu 325 330 335 Ile Leu Met Leu Thr Ser Lys Gly Met Ala Gly Val Pro Arg Ala Ser 340 345 350 Met Val Val Ile Ala Ala Thr Leu Asn Gln Phe Asn Ile Pro Glu Ala 355 360 365 Gly Leu Ile Leu Leu Met Gly Val Asp Pro Phe Leu Asp Met Gly Arg 370 375 380 Ser Ala Thr Asn Val Met Ser Asn Ala Met Gly Ala Ala Met Val Ser 385 390 395 400 Arg Trp Glu Gly Glu His Phe Gly Glu Gly Cys Arg Gly Lys Ala Leu 405 410 415 Lys Pro Asn Glu Ser Asn Val Ala Leu Pro * 420 425 <210> 1279 <211> 106 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5314..5631) <400> 1279 Met Lys Gln Ser Ile Val Ser Leu Ala Gln Val Ile Arg Ser Lys Asn 1 5 10 15 Ala Gly Pro Tyr Glu Leu Val Leu Asp Ile Leu Phe Lys Thr Lys Glu 20 25 30 Asn Tyr Glu Arg Val Lys Ser Ser Gly Gln Leu Thr Pro Glu Leu Ile 35 40 45 Ala Arg Leu Tyr His Val Glu Pro Asp Phe Ile His Arg Ile Val Trp 50 55 60 Phe Asp Pro Ser Asn Ala Val Lys Ile Val Met Pro Arg Asp Ile Ile 65 70 75 80 Ser Gly Asn Val Gly Asp Asn Asp Val Tyr Gly Ala Gln Gln His Ala 85 90 95 Pro Leu Leu Asn Met Ser Phe Asp Leu * 100 105 <210> 1280 <211> 457 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5628..6998) <400> 1280 Met Ala Arg Ser Phe Lys Val Leu Ser Pro Thr Ala Ile Leu Gly Tyr 1 5 10 15 Gly Phe Pro Glu Glu Ser Phe Arg Lys Ala Met Ala Glu Ser Pro Asp 20 25 30 Leu Ile Ala Val Asp Ala Gly Ser Ser Asp Pro Gly Pro His Tyr Leu 35 40 45 Gly Ala Gly Lys Pro Phe Thr Asp Arg Ala Gly Val Lys Arg Asp Leu 50 55 60 Arg Tyr Met Ile Thr Ala Gly Val Gln Asn Asn Ile Pro Val Val Ile 65 70 75 80 Gly Thr Ala Gly Gly Ser Gly Ala Ala Pro His Leu Glu Trp Cys Arg 85 90 95 Glu Ile Ile His Glu Ile Ala Arg Glu Glu His Leu Ser Phe Ser Met 100 105 110 Ala Leu Ile Pro Ala Asp Val Asp Lys Ala Ile Val His Gln Ala Leu 115 120 125 Asp Asn Gly Lys Ile Thr Ala Leu Asp Phe Val Pro Pro Leu Thr His 130 135 140 Asp Ala Ile Asp Glu Ser Thr Tyr Ile Val Ala Gln Met Gly Ile Glu 145 150 155 160 Pro Phe Gln Arg Ala Leu Lys Glu Arg Ala Gln Val Val Leu Gly Gly 165 170 175 Arg Ala Tyr Asp Pro Ala Cys Phe Ala Ala Leu Pro Ile Met Gln Gly 180 185 190 Phe Asp Glu Gly Leu Ala Leu His Cys Gly Lys Ile Leu Glu Cys Ala 195 200 205 Ala Ile Ala Ala Thr Pro Gly Ser Gly Ser Asp Cys Ala Met Gly Ile 210 215 220 Ile Asp Asp Asn Gly Phe Thr Leu Lys Thr Phe Asn Pro Lys Arg Lys 225 230 235 240 Phe Thr Glu Thr Ser Ala Ala Ala His Thr Leu Tyr Glu Lys Ser Asp 245 250 255 Pro Tyr Phe Leu Pro Gly Pro Gly Gly Val Leu Asn Leu Lys Gly Cys 260 265 270 Thr Phe Lys Ala Val Asn Asp Gly Glu Val Tyr Val Ser Gly Ser Lys 275 280 285 His Glu Glu Thr Pro Tyr Ala Leu Lys Leu Glu Gly Ala Arg Arg Val 290 295 300 Gly Phe Arg Cys Leu Thr Ile Ala Gly Thr Arg Asp Pro Ile Met Ile 305 310 315 320 Ala Gly Ile Asp Lys Ile Ile Asp Glu Val Lys Thr Ser Val Ser Arg 325 330 335 Asn Leu Ser Leu Asp Asp Asp Ser Ile Arg Ile Asn Phe His Leu Tyr 340 345 350 Gly Lys Asn Gly Val Met Gly Asp His Glu Pro Met Gln Thr Ala Gly 355 360 365 His Glu Leu Gly Ile Val Leu Asp Val Val Ala Pro Thr Gln Glu Ile 370 375 380 Ala Asn Ser Val Cys Ser Leu Val Arg Ser Thr Met Leu His Tyr Gly 385 390 395 400 Tyr Glu Asn Arg Ile Ala Thr Ala Gly Asn Leu Ala Phe Pro Phe Ser 405 410 415 Pro Ser Asp Ile Gln Gly Gly Pro Val Tyr Glu Phe Ser Ile Tyr His 420 425 430 Leu Ile Glu Ala Asn Asp Ala Leu Arg Phe Asp Phe His Ile Glu Gln 435 440 445 Val Thr Pro Glu Gly Val Gln Ala * 450 455 <210> 1281 <211> 414 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7002..8243) <400> 1281 Met Lys Ile Lys Gln Ala Leu Phe Thr Ala Gly Tyr Ser Ser Phe Tyr 1 5 10 15 Phe Asp Asp Gln Gln Ala Ile Lys Asn Gly Ala Gly His Asp Gly Phe 20 25 30 Phe Tyr Thr Gly Glu Pro Val Thr Gln Gly Phe Asn Ala Val Arg Gln 35 40 45 Ala Gly Glu Cys Val Ser Val Gln Leu Ile Leu Glu Asn Gly Ala Val 50 55 60 Ala Val Gly Asp Cys Thr Ala Val Gln Tyr Ser Gly Ala Gly Gly Arg 65 70 75 80 Asp Pro Leu Phe Leu Ala Glu His Phe Ile Pro Phe Leu Asn Asp His 85 90 95 Ile Lys Pro Leu Leu Val Gly Arg Asp Val Asp Ala Phe Leu Pro Asn 100 105 110 Ala Arg Phe Phe Asp Lys Leu Arg Ile Asp Gly Asn Leu Leu His Thr 115 120 125 Ala Val Arg Tyr Gly Leu Ser Gln Ala Leu Leu Asp Ala Thr Ala Leu 130 135 140 Ala Thr Gly Arg Leu Lys Thr Glu Val Val Cys Asp Glu Trp Gln Leu 145 150 155 160 Pro Arg Val Ala Glu Ser Ile Pro Leu Phe Gly Gln Ser Gly Asp Asp 165 170 175 Arg Tyr Ile Ala Val Asp Lys Met Ile Leu Lys Gly Ile Asp Val Leu 180 185 190 Pro His Ala Leu Ile Asn Asn Val Glu Glu Lys Leu Gly Phe Lys Gly 195 200 205 Glu Lys Leu Arg Glu Tyr Val Arg Trp Leu Ser Asp Arg Ile Leu Ser 210 215 220 Lys Arg Thr Ser Ala Arg Tyr His Pro Thr Leu His Ile Asp Val Tyr 225 230 235 240 Gly Thr Ile Gly Leu Ile Phe Asp Met Asp Pro Leu Arg Cys Ala Gln 245 250 255 Tyr Ile Ala Ser Leu Glu Lys Glu Ala Gln Gly Leu Pro Leu Tyr Ile 260 265 270 Glu Gly Pro Val Asp Ala Gly Asn Lys Pro Asp Gln Ile Arg Leu Leu 275 280 285 Thr Ala Ile Thr Lys Glu Leu Thr Arg Leu Gly Ser Gly Val Lys Ile 290 295 300 Val Ala Asp Glu Trp Cys Asn Thr Tyr Gln Asp Ile Val Asp Phe Thr 305 310 315 320 Asp Ala Ala Ser Cys His Met Val Gln Ile Lys Thr Pro Asp Leu Gly 325 330 335 Ser Ile His Asn Ile Val Asp Ala Val Leu Tyr Cys Asn Ser His Ser 340 345 350 Met Glu Ala Tyr Gln Gly Gly Thr Cys Asn Glu Thr Asp Val Ser Ala 355 360 365 Arg Thr Cys Val His Val Ala Leu Ala Ala Arg Pro Met Arg Met Leu 370 375 380 Val Lys Pro Gly Met Gly Phe Asp Glu Gly Leu Asp Ile Val Phe Asn 385 390 395 400 Glu Met Asn Arg Thr Ile Ala Leu Leu Gln Ala Lys Asp * 405 410 <210> 1282 <211> 482 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8243..9688) <400> 1282 Met Glu Leu Arg Asn Lys Lys Leu Thr His Asp Glu Phe Met Thr Glu 1 5 10 15 Arg Gln Gln Val Leu Lys Thr Trp Glu Thr Gly Lys Asp Val Glu Asn 20 25 30 Phe Glu Asp Gly Val Lys Tyr Gln Gln Thr Ile Pro Glu His Lys Arg 35 40 45 Phe Ser Leu Ala Leu Leu Lys Ala Asp Lys Glu Gly Lys Thr Leu Ser 50 55 60 Gln Pro Arg Ala Gly Val Ala Leu Met Asp Glu His Ile Glu Leu Leu 65 70 75 80 Lys Thr Leu Gln Glu Glu Cys Asp Leu Leu Pro Ser Thr Ile Asp Ala 85 90 95 Tyr Thr Arg Leu Asn Arg Tyr Glu Glu Ala Ala Val Gly Ile Lys Lys 100 105 110 Ser Ile Glu Ala Gly Thr Ser Lys Leu Asn Gly Leu Pro Val Val Asn 115 120 125 His Gly Val Ala Ala Cys Arg Arg Leu Thr Glu Thr Leu Gln Lys Pro 130 135 140 Leu Gln Ile Arg His Gly Thr Pro Asp Ala Arg Leu Leu Ala Glu Ile 145 150 155 160 Ser Met Ala Ser Gly Phe Thr Ser Tyr Glu Gly Gly Gly Ile Ser Tyr 165 170 175 Asn Ile Pro Tyr Ala Lys Arg Val Thr Leu Glu Lys Ser Ile Arg Asp 180 185 190 Trp Gln Tyr Cys Asp Arg Leu Met Gly Met Tyr Glu Glu His Gly Ile 195 200 205 Arg Ile Asn Arg Glu Pro Phe Gly Pro Leu Thr Gly Thr Leu Ile Pro 210 215 220 Pro Phe Ile Ser His Ser Ile Ala Ile Ile Glu Gly Leu Leu Ala Leu 225 230 235 240 Glu Gln Gly Val Lys Ser Ile Thr Val Gly Tyr Gly Gln Val Gly Ser 245 250 255 Leu Thr Gln Asp Val Ala Ala Ile Gln Ser Leu Arg Glu Leu Ala His 260 265 270 Glu Tyr Phe Gln Ser Tyr Gly Tyr Thr Asp Tyr Glu Leu Ser Thr Val 275 280 285 Phe His Gln Trp Met Gly Gly Phe Pro Glu Asp Glu Ser Lys Ala Phe 290 295 300 Ala Ile Ile Ser Trp Gly Ala Ala Val Ala Gly Met Ser Gly Ala Thr 305 310 315 320 Lys Val Ile Thr Lys Ser Pro His Glu Ala Trp Gly Ile Pro Thr Ala 325 330 335 Ala Ala Asn Ile Gln Gly Leu Lys Ala Ser Arg Gln Met Leu Asn Met 340 345 350 Val Asn Glu Gln Lys Phe Pro Pro Cys Pro Ala Val Glu Leu Glu Ile 355 360 365 Glu Leu Ile Lys Ser Glu Val Arg Ala Val Leu Asn Lys Val Phe Glu 370 375 380 Leu Gly Asn Gly Asp Ile Ala Arg Gly Thr Val Leu Ala Phe Glu Ala 385 390 395 400 Gly Val Leu Asp Val Pro Phe Ala Pro Ala Ala Cys Asn Ala Gly Lys 405 410 415 Ile Leu Pro Val Arg Asp Asn Thr Gly Ala Ile Arg Val Leu Glu Ala 420 425 430 Gly Ala Val Pro Leu Pro Lys Asp Ile Leu Asp Leu His His Asp Tyr 435 440 445 Val Ala Glu Arg Ala Arg Cys Glu Gly Arg Gln Pro Thr Phe Gln Met 450 455 460 Val Val Asp Asp Ile Asn Ala Val Ser His Ser Lys Leu Ile Gly Arg 465 470 475 480 Pro * <210> 1283 <211> 463 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9707..11095) <400> 1283 Met Gln Ile Val Ser Val Asp Ile Gly Ser Thr Trp Thr Lys Ala Ala 1 5 10 15 Leu Phe Thr Arg Glu Gly Asp Ala Leu Thr Leu Val Asn His Val Leu 20 25 30 Thr Pro Thr Thr Thr His His Leu Ala Lys Gly Phe Phe Ser Ser Leu 35 40 45 Asn Gln Val Leu Asn Val Asp Asn Ala Leu Pro Leu Leu Asn Ser Gly 50 55 60 Glu Val Ala Leu Lys Tyr Ser Ser Ser Ala Lys Gly Gly Leu Ala Val 65 70 75 80 Ala Ala Met Gly Leu Val Pro Ser Ile Thr Leu Glu Thr Ala Lys Val 85 90 95 Thr Ala His Ser Ala Gly Ala Lys Ile Ala Gln Tyr Tyr Ala Tyr Lys 100 105 110 Leu Asn Arg Arg Asp Ile Gln Ala Leu Glu Glu Thr Gln Pro Asp Ile 115 120 125 Leu Leu Phe Thr Gly Gly Thr Asp Gly Gly Glu Glu Ser Tyr Gly Leu 130 135 140 Asn Asn Ala Arg Val Leu Ala Glu Ser Lys Leu Asp Cys Ala Ile Ile 145 150 155 160 Tyr Ala Gly Asn Arg Asp Ile Gln Asp Glu Val Gln Glu Ile Leu Gly 165 170 175 His Lys Asp Leu Thr Ile Val Asp Asn Val Leu Pro Asp Leu Asp His 180 185 190 Pro Asn Pro Val Ala Ala Arg Gln Ala Ile Cys Asp Ile Phe Leu Lys 195 200 205 Arg Ile Val Lys Gly Lys Gly Leu Asp Val Ile Val Asp Lys Thr Gly 210 215 220 Glu Glu Pro Met Pro Thr Pro Trp Thr Val Phe Glu Leu Val Lys Ala 225 230 235 240 Ile Ser Asn Val Asp His Ser Trp Lys Glu Phe Met Leu Ile Asp Met 245 250 255 Gly Gly Ala Thr Thr Asp Val Tyr Ser Ala Cys Ala Asn Thr Leu Ser 260 265 270 Pro Asp Thr Val Leu His Gly Val Pro Glu Pro Phe Val Lys Arg Thr 275 280 285 Val Glu Gly Asp Leu Gly Met Arg Val Ser Ala Val Val Val Gly Glu 290 295 300 Ser Ala Lys Glu Leu Val Asn Val Asn Phe Ala Gln Gln Pro Ala Gln 305 310 315 320 Leu Asp Ala Phe Tyr His Tyr Leu Arg His Leu Val Ala His Pro Asp 325 330 335 Tyr Leu Pro Ala Asn Ala Glu Glu Lys Tyr Phe Asp Thr Val Leu Ala 340 345 350 Gly Leu Cys Val Gly Tyr Ala Thr Glu Arg His Ala Gly Thr Lys Lys 355 360 365 Glu Val Cys Thr Cys Val Gly Asn Val Asp Leu Gln Met Gly Arg Asp 370 375 380 Leu Thr Thr Val Arg Lys Val Val Gly Ser Gly Gly Trp Leu Ser Arg 385 390 395 400 Ala Ser Gln Phe Asp Met His His Trp Leu Lys Tyr Arg Glu Leu Asn 405 410 415 Asp Asp Gly Lys Arg Ile Leu Leu Pro Thr Glu Phe Glu Tyr Tyr Arg 420 425 430 Asp Ser Arg Gly Leu Leu Pro Leu Leu Ala Asn Val Ala Arg Val Asp 435 440 445 Pro Leu Ala Ala Ala Arg Thr Ser Ile Gln Cys Leu Thr Leu * 450 455 460 <210> 1284 <211> 150 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11095..11544) <400> 1284 Met Lys Lys Ala Thr Leu Val Ile Gly Val Ile Gly Ala Asp Cys His 1 5 10 15 Ala Val Gly Asn Lys Val Leu Asp Arg Val Phe Ser Asn His Asp Phe 20 25 30 Arg Val Ile Asn Leu Gly Val Met Val Ser Gln Asp Glu Tyr Ile Asp 35 40 45 Ala Ala Ile Glu Thr Gly Ala Asp Ala Ile Val Val Ser Ser Ile Tyr 50 55 60 Gly His Gly Asp Ile Asp Cys Leu Gly Met Arg Glu Arg Cys Ile Glu 65 70 75 80 Arg Gly Leu Gly Asp Ile Leu Leu Tyr Val Gly Gly Asn Leu Val Val 85 90 95 Gly Lys His Asp Phe Ala Asp Val Glu Thr Lys Phe Lys Glu Met Gly 100 105 110 Phe Asp Arg Val Phe Ala Pro Ser His Asp Leu Glu Asp Val Cys Gln 115 120 125 Leu Met Ala His Asp Ile Asn Gln Arg His Asp Val Asp Thr Arg Ile 130 135 140 Leu Glu Glu Ala Ile * 145 <210> 1285 <211> 56 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11731..11898) <400> 1285 Met Asn Cys Ser Glu Ile Arg Leu Lys Ser Tyr Glu Met His Leu Leu 1 5 10 15 Met Ala Lys Thr Thr Ser Gln Lys Cys Lys Leu Glu Val Asp His Asn 20 25 30 Tyr Leu Asn Thr Leu Asn Gln Val Asn Phe Lys Asn Leu Thr Leu Met 35 40 45 Thr Leu Val Asp Ile Thr His * 50 55 <210> 1286 <211> 141 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12092..12514) <400> 1286 Met Ile Pro Ser Gln Ile Ser Phe Asn Thr Leu Pro Val Asn Ala Thr 1 5 10 15 Tyr Ala Ser Glu Thr Thr Val Asp Thr Gln Lys Phe Ser Asp Ile Leu 20 25 30 Tyr Ser Ala Gly Cys Ser Leu Lys Asp Met Ala Tyr Leu Ser Arg Cys 35 40 45 Leu Ala Ser Ile His Pro Thr Leu Ala Lys Asn Ile Tyr Glu Thr Glu 50 55 60 Asn Leu Ser Asp Gln Lys Leu Leu His Ile Asp Cys Arg Ser Thr Asn 65 70 75 80 Glu Ile Lys Ile Asn Ile Phe Phe Gly Gln Gln Arg Glu Gly Leu Ile 85 90 95 Glu Ile Asn Ser Asp Thr Val Ile Phe Ser Ile Leu Ser Ser Leu Ile 100 105 110 Asp Ser Ala Ile Ser Lys Phe Gln His Gln Ile Pro Val Asn Gly Ser 115 120 125 Val Asn Arg Glu Leu Leu Tyr Glu Asp Tyr Thr Asp * 130 135 140 <210> 1287 <211> 315 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(12596..13540) <400> 1287 Met Ser Pro Asp Asn Ile Gly Ser Ala Val Asn Arg Phe Ser Gly Trp 1 5 10 15 Pro Ser Asn Asp Ser Leu Lys Thr Asp Lys Glu Ser Met Thr Ser Pro 20 25 30 Val Thr Val Gln Val Ile Lys Met Ile Ala Ala Ile Leu Asp Pro His 35 40 45 Arg Ile Val Val Gly Ile Asp Thr Leu Tyr Thr Thr Gln Arg Glu Thr 50 55 60 Phe Thr Ser Glu Ser Gln Gln Leu Ile Glu Ser Ala Leu Gln Thr Leu 65 70 75 80 His Val Met Asn Leu Asn Asn Leu Glu Thr Asn Arg Asp Glu Glu Ser 85 90 95 His Tyr Leu Ala Phe Glu Tyr Asn Val Asp Thr Ser Asp Arg Ile Thr 100 105 110 Val Ser Ala Tyr Asn Glu Lys Lys Pro Gly Cys Tyr Gly Gln Cys Leu 115 120 125 Val Ile Gln Asp Asp Glu Thr Asp Leu Phe Asn Leu Ile Lys Ile Lys 130 135 140 Ile Phe Glu Ala Arg His Asn Tyr Val Ala Gln Leu Met Ser Asp Pro 145 150 155 160 Glu Phe Met Phe Lys Phe Ser Tyr Ser Ala Gln Gln Asn Arg Leu Glu 165 170 175 Pro His Leu Leu Val Pro Ala Tyr Phe Pro Leu Lys Thr Asn Glu Pro 180 185 190 Val Thr Gln Glu Asp Val Leu Leu Leu Tyr Arg Phe Phe Lys Met Asn 195 200 205 Asp Asp Phe Asn Lys Leu Thr Ser Asp Glu Tyr Met Ser Ile Leu Thr 210 215 220 Pro Leu Met Lys Cys Glu Arg Ser Val His Asp Asn Asn Arg Tyr Val 225 230 235 240 Thr Gly Lys Asp Thr Leu Leu Leu Asp Tyr Pro Pro Ser Gly Asn Gln 245 250 255 Ile His Phe His Val Phe Pro Asp Glu Ser Ala Thr Leu Val Leu Tyr 260 265 270 Phe Ser Asn Asn Asp Ile Glu Cys Phe Val Phe Glu Arg Asp Ile Pro 275 280 285 Ser Gln Tyr Arg Phe Phe Lys Met Phe Thr Asn Leu Ala Leu Val Ile 290 295 300 Asp Gln Leu Thr Glu Ala Asn Lys Ile Leu * 305 310 <210> 1288 <211> 12802 <212> DNA <213> Escherichia coli O157:H7 <400> 1288 ttattacaac gattcttata aaaaagaaaa gccttgcaca tatagcaaag cttttcactt 60 ctcaggattt cttacaccaa gaaaccatca acaataacaa aatgcaatta ttatatgtta 120 actacatatg catttcatta aaaccaatca taaatgctta tcatacttta attgctataa 180 ttgattgcct tctatttttt caactcgagt ggttgaaaca tcattcttaa atccactcca 240 ccattttctt agcttattgt ttattggctt ttcaaaaaac aaatacatca ttattgatat 300 aaataatgaa gcaaacagag ccattactat aaatttaatt acacttatag caccaagacc 360 agaaacatta aagaacttgc tcaatgtact gattactata gtatggacca agtaaaatga 420 aaaagaagca tcacctaaaa gtatcataac tttatttgat attatttttg aaataatacc 480 accattaaac gaaaacacta atattgaaaa ggccattgat ggtataaaaa gcgcatcata 540 ctgtaatcca ttgctatttt gactttttgc caccatatag acagacatta ggataaagac 600 tacagatgat atttcagcaa atgatagaac taaatatgac ggctttgact taaactcaaa 660 atctccggcc tgattgctgc ggattgtctc tgccagcctg cctcggtcaa tctcacgacc 720 agccatcttg tcctgaacat tgaagtagtc aatcggaccg agagcagcca tcccaaggtg 780 ataaacaaac tcaccaaacc ctgaaggatt ctgctgatac atctgagcaa cgttgttagg 840 gtcaacaccg acgcgcgcca gttccttggc gttgttttgc agccatgatt gcattgcttc 900 tggagacgag gccgcaaggc gtgcgccagc cgctaaggtg ccgatagaat tgcgctggtc 960 ttcgtctgcc cacttcatac cagactgaat cttctctaat tgaccaggat atttggtcat 1020 cagatctcga acctgctgtc gatcgccgga ctggatggct gccgcatatt ctttttggaa 1080 tgcagcatcc gcttcctgtt gctttgcggc ttgagatgtt tgagcgacac taccaagtcc 1140 ctgcaacgcc tgaaggccga tgttattgcg acctgaacgc tccatttcgt tgttctggcg 1200 aatataggcc aacgcctcac ttacatcact tgcctttggc gcatttgagt tttgcccacc 1260 gataccagca agaaaaccgc ctgagttgat tccttgttgc caagtagcca tattcccacc 1320 ttaaaacaat gatccaagac caccgataac accgccagca agagcaccaa taccagtccc 1380 aataacagga actgcactac caatcattgc acctgatgcg gccccaccaa tggcacctgt 1440 agcaaaactc tgtaggcctg aaggcttatt cgcatttgct gccgatgctg ccgcctgctg 1500 ttgatacaat tggctgacat tgttagcgta gttctgtccg gcgtttgcct gacctgtaag 1560 agcaccaagg ccgatatttg ccagattgtt gtagttgttc atctgacctg acagccagtt 1620 ttgaccgagt gtaggtgcga ttgctgctaa ctggtttcct gttgctgtag agcctaatcc 1680 acccgttgcc tctgctgctg ccagactctg atagcgcgcc tgccctgcaa ggtctttata 1740 ctgctgagag ttgtaatact ggttaagcgc ctgaccttgc ccctgaagag aggaaagatt 1800 ctgcaactgt gatacgtact gctgagcgag tggcgtgaac ggtgcaaggt tttgcatgtt 1860 cgtctgccac atttcacgct gcagttcgat gcccttttca gttgcgcgtg cctgggcttt 1920 agatccggag tcgctgccgc ctttcatata cccattcatg ggaagcaatt tattcttgaa 1980 gctttcgcta agtactaaca tttaatagct cctcatattt cgaacgaggt aattgataga 2040 gggtgattcc taccggtttt ccgttactca tgtacgcatc atcaaggtga ccaacacggg 2100 tagcgccaag caaacggata attgcccgtc cgtatttggt ggtgtcagga accatggtga 2160 tgctgttaag gaatggtgag ttttcgagaa gccatttgca gaataatcga tgcccttgta 2220 gtgcatattc gccacggaat ccggggtcat acaccgcatg gcattcaaca acgctatgcc 2280 agaagttacg cacttcatga actccagcca gcactaatcc ttcgtagatg ccgagatata 2340 ccgcatcagg cttgatgtag tatttatctc cactgtctac gatattcccc gtgtttaccg 2400 ggttgttaag gaattctgca agtttcaccg ggttatcgat gagctttatt tccatcactg 2460 ctccgcaatg attttgatgg ttgtggcagt aaacgccgcg ccattcgact gaatggttaa 2520 cgtgctgcca tttgtggcaa gaaagccgtc tttatccacg ctgaagaacg tagctaacag 2580 gatgttgtcg gttgttgttg ccgagttgcg actgcttact agcgtgtcag gaacagaacc 2640 ggagaatgtt agctgcattg acctgttggc ggttccgctg ggccacgtcc cgacaatcga 2700 cagcttgaag aacaaggttt tgttctcgtt gaacacaacc atcttgttgt taacggtgtc 2760 gaagaatggt gccaacgtcc cggatgacgg cgtaagcgtt ttcagcaggc taacaaggtt 2820 ggtcggcgct gtcgggatgg ttactgatac gccagagtaa acaacctctg acttcttgcg 2880 cgtagtggca tactccagag cattaatgcg cgtttcatgg tctgaaacct gcgattccag 2940 cgactgaact ctggtatcaa gcgatgcaat atcgctttca ttcaaggcaa tcagtgggtt 3000 tacgtcatgg agtgggctca acaccagtca gagccgcatg tacacgcaat aatcatggtg 3060 aacgaaagaa gcattaatgg gcaagctggc aaaattgtca gcaaatgggt aacactggca 3120 aacaatgcaa tcccatcaaa tgttcctccc cagtgggatc tagatttgaa aggtcagcaa 3180 tattcagagc ctacaaagtg tataggtaaa cagattgatt acatggcaaa gcccgaaact 3240 aagttaaatg actttaatag agaggcgagc aagagcctat atgattggtc agatgccaac 3300 gtttggggtt attcgaatgg ctgggcgcgg catgagataa aaaaagaaac actttctatc 3360 actggctttc atgctgtaag acgcatacta aaagccgttc aggcatcaag gaaagacaac 3420 tacaaagcta agcgacagat acagcgtaca ttgaaacgac aagacataaa tcgatcacca 3480 atcaccccgt tccaagcacc gttaattagc aaacacgatt gggatttatc agtgatagcg 3540 gtcaccaaag aggcagagac agagcgcagg gaattactat cctcacagat aataaactcg 3600 aacaaagtac aaacccaccc actgttaagg atgttaagaa gagcacgagt gagagcatcc 3660 agagccaaaa gagaaagcgg aggttatgac cattactact agtagtgaca gatcgtgaca 3720 aggcggtgca aaaaacgacc aataataaga gagatatgcc tgccaaaccg ccaaaagcgc 3780 ggagcgcggc aaacgccgcg agaggcgcaa gaaggcgaac ctatccattg aaacggtcag 3840 aagcgcatcg cgctcgacga ccgaagtccc cactaacacc gttaacgaaa gatcaaagtc 3900 ttagaaaaaa atgacgtttc tttgatggac ttccatccgt aaaaatcaaa ttttgagaaa 3960 aagtacttat agaaattaat cgctctataa ggataagttg acgttagttt aaagtgataa 4020 aacattaaag aaaaaacgta aaatcaaata cataaaataa gtcaccaagg gatcattttc 4080 agaaaacaac gtcaacgtaa cgtcaactct gtaagaactt ttttggtcac tttttgggtt 4140 gaatgtacgt aaaaatcccc agcagtgaaa tttgagcgcg taagcacaat tctgaggggc 4200 tttttgtctg taggttaggc agtgtaacta acaatacaag aagttagctc tgactaacta 4260 tttaattaac ttttcaatct aattgcgtta gatattatac cctaacgcaa tatttttaat 4320 tcaataatgt ctgtaaattg ttattactta taattataca tttaactata tctacattgg 4380 ctgcttccaa ttactactta cgtaacggaa tctcggatcc tctgtttttg gctcggtata 4440 ataagaatca tcaatagtaa agttcgacgc taatttatcc cgaagcccac ctaaacgttc 4500 aatgcttgtt agttcgttag taacatcctt gaaaacggta gaaaatgctt tatgttgttt 4560 agacttcata aattcaggag tgctcagtgc aaactcttta tcaggcaaac ctggaatacc 4620 cacgagtcct gtcaatgaat ttatacattt tatcaaaaaa ctgccttgaa taccttgatt 4680 tgatggaaca ccgtagcttc gtttaatatc tccagatatt ttatctaaat cacttagtaa 4740 ttttgttact tttttatttc ctgcacttat ccccgattca tcgtaggtca catgaatctc 4800 tcggattaca tctcgacacg tacgaaaatg atcatgtgtt ctaagctcta aagctgaatt 4860 gataacttga gagacatttc ctgtttcgtt tgctagccat gcagaaaata ttggtaaatc 4920 taatgaaata gtagatgtgc gtccatgatc tacaatttca gatcttgcag tactgatttt 4980 atcagacaac gattgcacca accttgcagt ataatcatga ccaaaagcac ctgttttttt 5040 catccaatgc aattgatatg catgccttat tggatgaata aatgagtctg ctttaaaatg 5100 cttagcaatg acgctgtaat aaatagattt atatgccaac caatttagcg atgcgataaa 5160 catttcaagt gaacgagtca tacctccttt accgcgagta gatttttccc tttctagttc 5220 aaattcacgc tcagtatatt catgtccaga tgaactcact agcttcacat cggttgacca 5280 gtaccctttc gtatcagaag catctgataa ttcattaaaa atcgatgcac ttagttcact 5340 atatttcgca tattcaggag taccgggctg accaagcatt ttcattgtta agtaatacac 5400 gctagaccga agatcccatg tgcaaatcat attcagctta agcatctcta caagttgcct 5460 aaaatcatcg tcaacaaact ccccacctct aatttcggaa gtaatttgcc gagattcaac 5520 ttgtgctaac tgatcaagtt cactgagttg aaaatcactt tcagatacaa atttaataaa 5580 gtcaaattta gcaatgcgtt tatctctata ttctttttta taattatcta cacagatcag 5640 ggtatcgtaa aaaagtatcg cttgaataag attttcaaaa gcgactaaat ctccgttaat 5700 agtatctgga ttcttaacaa gaatatcacc cagtgttctt tcgactgctg ttaacgaagc 5760 attatcaatc aacgcataag acattaaact acctccatta gataatatct aataacatta 5820 tatttcaatt aggtttaaaa attgtgatac ttatgacaga tttgagtgac attttatcaa 5880 tctactgatt ttgatggtga aatttattag aaggtatgcg tagtgctacg ggagaaatga 5940 gaaacgcgcc cagcaatggc gcatcctttc ttaagcaagt tggctagtat ctatagcatc 6000 catccaatca ggagcaattc ccaaacgttc cgcgaactct tcattggtca cgtcttccat 6060 tgagagacta gccagacaat cgttaatttc agaatagacg ggggaaagta ataggtattc 6120 ccgcaactct ttcaggtctt tttccatctt aacactcctt gttaatagac cgtcgaacaa 6180 tggtacagat ttgtaccatt ccaagtactg gcaagcaacc ccaccagcac aacaaattat 6240 ctcatacggt aaaaacggtg tcgggctgtt tctttcggct agctcaatat atcaccttaa 6300 acaccagccg ttatcattgt ctcaattggg tataccgtaa tgacaaggtg atacaaagtc 6360 tcaatagggt tgtataggaa cattttgact acacaaactg cattatgtat catttgcact 6420 tatattcaca acccttttga gacaatgcaa tgaacgttag aatttactgc cgagcatcaa 6480 ctgaggggca acacgctgat cgagcactta ccagcctacg tgaattttca aaatcaaaag 6540 gctggcagat tgcaggagag tatatagaaa atgctagcgg ggcgaagctt gagcgcgtag 6600 agcttatgcg gctattgtct gaagcccagt ccggcgatct gttgctagtg gaagctatag 6660 atcgtctgag tcgcctagaa catagtgcat gggtcgaact gaaagatacg ctcaaccgaa 6720 aagggttaat catcgtatca atggatttac caacgagctg gcagatggtc gagatggcag 6780 gcaatgatct aaccagcggc atcctgagag ccgtaaatgc catgttgatt gatatccttg 6840 ccacaatggc acggcaggat tacgaaacac gccgtaaacg ccaacagcaa ggcattgaac 6900 gagctaaaag cgaaggcata tacattggga gggcgaaaaa tcaggaagcc cgagagatcg 6960 ttagagagat gttggagcaa ggagtaaaac ctgaactcat catgaaggca gcaggaatca 7020 gccgagcgac ttactaccgg ataaaaaacg agctattgat cgtaaaatca gaataaaatt 7080 tgaaaggtcg tcaggcttgt ttcatcaggt aaaaaccagc atttctgatc acaacgcttg 7140 ggggcaccta ttggggcact caccaaaatc gaaagagaaa taaactacaa ttcaaattgt 7200 tagctaattt ttcgattcct gcagggacac cagataccct tcaaaccaaa tctaccttca 7260 tcccgtaaac gatgggtttg gcagcacact tgccctatat ctactcattt ttactgcaac 7320 aggttgaaat ctcagcactg tcagaaagcg ctgatgacta aacagcccag ggccgggcga 7380 tgtaaccatc acacagaatc ctgatagcga aatacggcgt gactcgatac ttcactccgc 7440 aatgcattcc ttgatgaatt cgcaggcccg tgatacacgg gacaggtcgc agaatgacga 7500 caatgtcctg gaaatcagcg aaccgtgtat ccggagtaca tttgagcgac tgtaccagaa 7560 catgaatgag gtgtttggat taggcgatta ttagcagggc taagcatttt agtattatta 7620 ttttccggtt gaaggatatg gagatatcga caacaaccgg aaaaagttta cgtctatatt 7680 gctgaaggta caggcgtttc cataactatt tgctcgcgtt ttttactcag gaagaaaatg 7740 ccaaatagca acatcaggca gacaataccc gaaattgcga agaaaactgt ctggtagcct 7800 gcgtggtcaa agagtatccc agtcggcgtt gaaagcagca caatcccaag cgaactggca 7860 atttgaaaac caatcagaaa gatcgtcgac gacaggcgct tatcaaagtt tgccacgctg 7920 tatttgaaga cggatatgac acaaagtgga acctcaatgg catgtaacag cttcactaat 7980 gaaataatcc aggggttaac gaacagcgcg caggaaagga tacgcaacgc cataatcaca 8040 acaccgataa gtaatgcatt ttttggccct acccgattca caaagaacgg aataatcgcc 8100 atgcacagcg cttcgagtac cacctggaat gagttgagat aaccatacag gcgcgttcct 8160 acatcgtgtg attcgaataa acctgcataa aagacaggaa aaagttgttg atcaaaaatg 8220 ttatagaaag accacgtccc aacaataaat atgacgaaaa cccagaagtt tcgatccttg 8280 aaaactgcga taaaatcctc tttttttacc cctcccgcat ccgccgctac gcactggtga 8340 tccttatctt taaaacacat gttgatcatc ataaatacag cgccaaatag cgagaccaac 8400 cagaagttga tatggggact gatactaaaa aatatgccgg caaagaacgc gccaatagca 8460 tagccaaaag atccccaggc gcgcgctgtt ccatattcga aatgaaaatt tcgcgccatt 8520 ttttcggtga agctgtcaag caaaccgcat cccgccagat accccaggcc aaaaaagagc 8580 gcccccagaa ttagacctac agaaaaattg ctttgcagta acggttcata aacgtaaatc 8640 ataaacggtc cggtcaagac caggatgaaa ctcatacacc agatgagcgg tttcttcaga 8700 ccgagtttat cctgaacgat gccgtagaac atcataaata gaatgctggt aaactggttg 8760 accgaataaa gtgtacctaa ttccgtccct gtcaacccta gatgtccttt cagccaaata 8820 gcgtataacg accaccacag cgaccaggaa ataaaaaaga gaaatgagta actggatgca 8880 aaacgatagt acgcatttct gaatggaata ttcagtgcca taattacctg cctgtcgtta 8940 aaaaattcac gtcctattta gagataagag cgacttcgcc gtttacttct cactattcca 9000 gttcttgtcg acatggcagc gctgtcattg cccctttcgc cgttactgca agcgctccgc 9060 aacgttgagc gagatcgata attcgtcgca tttctctctc atctgtagat aatcccgtag 9120 aggacagacc tgtgagtaac ccggcaacga acgcatctcc cgcccccgtg ctatcgacac 9180 aatccacaga cattccagca aaatggtgaa cttgtcctcg ataacagacc accacccctt 9240 ctgcaccttt agtcaccaac agcatggcga tctcatactc ttttgccagg gcgcatatat 9300 cccgatcgtt ctgtgttttt ccactgataa gtcgccattc ttcttccgag agcttgacga 9360 catccgccag ttgtagcgcc tgccgcaaac acaagcggag caaatgctcg tcttgccata 9420 gatcttcacg aatattggga tcgaagctga caaaacctcc ggcatgccgg atctccgtca 9480 tcgcagtaaa tgcgctggta cgcgaaggct cggcagacaa cgcaattgaa cagagatgta 9540 accattcgcc atgtcgccag cagggcaagt ctgtcgtctc taaaaaaaga tcggcactgg 9600 ggcggaccat aaacgtaaat gaacgttccc cttgatcgtt cagatcgaca agcaccgtgg 9660 atgtccggtg ccattcatct tgcttcagat acgtgatatc gactccctca gttagcagcg 9720 ttctttgcat taatgcacca aaaggatcat cccccacccg acctataaac ccacttgttc 9780 cgcctaatct ggcgattccc accgcaacgt tagctggcgc gccgccagga caaggcagta 9840 gccgcccgtc tgattctggc aagagatcta cgaccgcatc ccctaaaacc catactttgg 9900 ctgacatttt tttcccttaa attcatctga cttacgcata gtgataaacc tctttttcgc 9960 aaaatcgtca tggatttact aaaacatgca tattcgatca caaaatgtca tagttaacgt 1002 0 taacatttgt gatattcatc gcatttatga aagtaaggga ctttattttt ataaaagtta 1008 0 acgttaacaa ttcaccaaat ttgcttaacc aggatgataa aaatgacgca atctcgattg 1014 0 catgcggcgc aaaacgcact agcaaaactt cacgagcgcc gaggtaacac tttctatccc 1020 0 cattttcacc tcgcgcctcc tgccgggtgg atgaacgatc caaacggcct gatctggttt 1026 0 aacgatcgtt atcacgcgtt ttatcaacat cacccaatga gtgaacactg ggggccaatg 1032 0 cactggggac atgccaccag cgacgatatg atccactggc agcatgagcc tattgcgcta 1038 0 gcgccaggag acgagaatga caaagatggg tgtttttcag gtagtgctgt cgatgacaat 1044 0 ggtgtcctct cacttatcta caccggacac gtctggctcg atggtgcagg taatgacgat 1050 0 gcaattcgcg aagtacaatg tctggctacc agtcgggatg gtattcattt cgagaaacag 1056 0 ggtgtgatcc tcactccacc agaaggaatc atgcacttcc gcgatcctaa agtgtggcgt 1062 0 gaagccgaca catggtggat ggtagtcggg gcgaaagacc caggcaacac tgggcagatc 1068 0 ctgctttatc gcggcagttc attacgtgaa tggactttcg atcgcgtact ggcccacgct 1074 0 gatgcgggtg aaagctatat gtgggaatgt ccggactttt tcagccttgg cgatcagcat 1080 0 tatctgatgt tttccccgca gggaatgaat gccgagggat acagttaccg aaatcgcttt 1086 0 caaagtggcg taatacccgg aatgtggtcg ccaggacgac tttttgcaca atccgggcat 1092 0 tttactgaac ttgataacgg gcatgacttt tatgcaccac aaagctttgt agcgaaggat 1098 0 ggtcggcgta ttgttatcgg ctggatggat atgtgggaat cgccaatgcc ctcaaaacgt 1104 0 gaaggctggg caggctgcat gacgctggcg cgcgagctat cagagagcaa tggcaaactt 1110 0 ctacaacgcc cggtacacga agctgagtcg ttacgccagc agcatcaatc tatctctccc 1116 0 cgcacaatca gcaataaata tgttttgcag gaaaacgcgc aagcagttga gattcagttg 1122 0 cagtgggcgc tgaagaacag tgatgccgaa cattacggat tacagctcgg cactggaatg 1128 0 cggctgtata ttgataacca atctgagcga cttgttttgt ggcggtatta cccacacgag 1134 0 aatttagacg gctaccgtag tattcccctc ccgcagcgtg acacgctcgc cctaaggata 1140 0 tttatcgata catcatccgt ggaagtattt attaacgacg gggaagcggt gatgagtagt 1146 0 cgaatctatc cgcagccaga agaacgggaa ctgtcgcttt atgcctccca cggagtggct 1152 0 gtggtgcaac atggagcact ctggcaactg ggttaacata atatcaggtg gaacaacgga 1158 0 tcaacagcgg gcaagggatc cgcgtcacac ttcccccttc acgaccttca ataatatgca 1164 0 atgcagcttc ccgcccgata atgtcatgtg gaagctgaat tgtggtcagc ggcggtaaaa 1170 0 acagatgccc gacgccaacc agattatcaa agcccattac ggcgacatcc tgcgggatac 1176 0 gtaccccctt agccaggaga acctgataag ccacaaaggc tgcgcgatcg ttaccacata 1182 0 tcagaacatc aaaatctggt ttgcccgatt tgaagtggtc attgagtaaa cttgcgagat 1188 0 cggtgtagtg atcatcacct gttgccatgt gaaattgttt cacctcagcc agatctcgtc 1194 0 cagcatcacg ccaggcctgc tcaaatccct gccgacgata ccctgttgcc aacgcacttt 1200 0 ccggtagcca gaagcataac ggttgacgat agcccgccgc gagcaaatgc tgtgttgatt 1206 0 catattgtgc agtgtaatca tcagggatat aactgggtaa cgctgggtca tccgccacac 1212 0 agttcgccaa tacaatattt tcaccataca gagactcagg tagcgtgata tgtcgcagcc 1218 0 ccattgtagt atagataatg ccatccggac ggtgggcaag cagctgacgt gccgcgcggg 1224 0 cagcgtcatc ttcagaaaaa atattgatta aaaaactatt ccagccgaac tcgctggcgg 1230 0 tttgctcaat ggcaagcaga atatcaacag agaaaggagt ggtagcagtg tcctgcgcca 1236 0 gcacggcgag agtcgacggc ttacgtcctt gagcgcgcat cttacgggcg gaaagatcag 1242 0 gaacataatt cagggtctgg attgcctgca atacgcggtc acgcgttgca ggacgcacag 1248 0 attctgcatt atgcatcacc cgggagactg tcatcatcga cactcccgcc aggcgtgcga 1254 0 catcctttaa tgaagccata cccaagccgt ttgccgtaaa acgggcactg tagcagaaac 1260 0 agacgtcact ggcgagatcc aacgaaattc tcgacgccct atcacccgac acggcaatac 1266 0 aataaaaaat aacaataatt gccggataat tgtacccaat tccgcctctg ttctcgccaa 1272 0 cgagtgacca tataggcaag taagaaaaac atgccaactg gcatcgccaa cctggagaag 1278 0 aaaatataaa tatggatcat tg 1280 2 <210> 1289 <211> 379 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(175..1311) <400> 1289 Met Ala Thr Trp Gln Gln Gly Ile Asn Ser Gly Gly Phe Leu Ala Gly 1 5 10 15 Ile Gly Gly Gln Asn Ser Asn Ala Pro Lys Ala Ser Asp Val Ser Glu 20 25 30 Ala Leu Ala Tyr Ile Arg Gln Asn Asn Glu Met Glu Arg Ser Gly Arg 35 40 45 Asn Asn Ile Gly Leu Gln Ala Leu Gln Gly Leu Gly Ser Val Ala Gln 50 55 60 Thr Ser Gln Ala Ala Lys Gln Gln Glu Ala Asp Ala Ala Phe Gln Lys 65 70 75 80 Glu Tyr Ala Ala Ala Ile Gln Ser Gly Asp Arg Gln Gln Val Arg Asp 85 90 95 Leu Met Thr Lys Tyr Pro Gly Gln Leu Glu Lys Ile Gln Ser Gly Met 100 105 110 Lys Trp Ala Asp Glu Asp Gln Arg Asn Ser Ile Gly Thr Leu Ala Ala 115 120 125 Gly Ala Arg Leu Ala Ala Ser Ser Pro Glu Ala Met Gln Ser Trp Leu 130 135 140 Gln Asn Asn Ala Lys Glu Leu Ala Arg Val Gly Val Asp Pro Asn Asn 145 150 155 160 Val Ala Gln Met Tyr Gln Gln Asn Pro Ser Gly Phe Gly Glu Phe Val 165 170 175 Tyr His Leu Gly Met Ala Ala Leu Gly Pro Ile Asp Tyr Phe Asn Val 180 185 190 Gln Asp Lys Met Ala Gly Arg Glu Ile Asp Arg Gly Arg Leu Ala Glu 195 200 205 Thr Ile Arg Ser Asn Gln Ala Gly Asp Phe Glu Phe Lys Ser Lys Pro 210 215 220 Ser Tyr Leu Val Leu Ser Phe Ala Glu Ile Ser Ser Val Val Phe Ile 225 230 235 240 Leu Met Ser Val Tyr Met Val Ala Lys Ser Gln Asn Ser Asn Gly Leu 245 250 255 Gln Tyr Asp Ala Leu Phe Ile Pro Ser Met Ala Phe Ser Ile Leu Val 260 265 270 Phe Ser Phe Asn Gly Gly Ile Ile Ser Lys Ile Ile Ser Asn Lys Val 275 280 285 Met Ile Leu Leu Gly Asp Ala Ser Phe Ser Phe Tyr Leu Val His Thr 290 295 300 Ile Val Ile Ser Thr Leu Ser Lys Phe Phe Asn Val Ser Gly Leu Gly 305 310 315 320 Ala Ile Ser Val Ile Lys Phe Ile Val Met Ala Leu Phe Ala Ser Leu 325 330 335 Phe Ile Ser Ile Met Met Tyr Leu Phe Phe Glu Lys Pro Ile Asn Asn 340 345 350 Lys Leu Arg Lys Trp Trp Ser Gly Phe Lys Asn Asp Val Ser Thr Thr 355 360 365 Arg Val Glu Lys Ile Glu Gly Asn Gln Leu * 370 375 <210> 1290 <211> 227 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1321..2001) <400> 1290 Met Leu Val Leu Ser Glu Ser Phe Lys Asn Lys Leu Leu Pro Met Asn 1 5 10 15 Gly Tyr Met Lys Gly Gly Ser Asp Ser Gly Ser Lys Ala Gln Ala Arg 20 25 30 Ala Thr Glu Lys Gly Ile Glu Leu Gln Arg Glu Met Trp Gln Thr Asn 35 40 45 Met Gln Asn Leu Ala Pro Phe Thr Pro Leu Ala Gln Gln Tyr Val Ser 50 55 60 Gln Leu Gln Asn Leu Ser Ser Leu Gln Gly Gln Gly Gln Ala Leu Asn 65 70 75 80 Gln Tyr Tyr Asn Ser Gln Gln Tyr Lys Asp Leu Ala Gly Gln Ala Arg 85 90 95 Tyr Gln Ser Leu Ala Ala Ala Glu Ala Thr Gly Gly Leu Gly Ser Thr 100 105 110 Ala Thr Gly Asn Gln Leu Ala Ala Ile Ala Pro Thr Leu Gly Gln Asn 115 120 125 Trp Leu Ser Gly Gln Met Asn Asn Tyr Asn Asn Leu Ala Asn Ile Gly 130 135 140 Leu Gly Ala Leu Thr Gly Gln Ala Asn Ala Gly Gln Asn Tyr Ala Asn 145 150 155 160 Asn Val Ser Gln Leu Tyr Gln Gln Gln Ala Ala Ala Ser Ala Ala Asn 165 170 175 Ala Asn Lys Pro Ser Gly Leu Gln Ser Phe Ala Thr Gly Ala Ile Gly 180 185 190 Gly Ala Ala Ser Gly Ala Met Ile Gly Ser Ala Val Pro Val Ile Gly 195 200 205 Thr Gly Ile Gly Ala Leu Ala Gly Gly Val Ile Gly Gly Leu Gly Ser 210 215 220 Leu Phe * 225 <210> 1291 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1988..2455) <400> 1291 Met Glu Ile Lys Leu Ile Asp Asn Pro Val Lys Leu Ala Glu Phe Leu 1 5 10 15 Asn Asn Pro Val Asn Thr Gly Asn Ile Val Asp Ser Gly Asp Lys Tyr 20 25 30 Tyr Ile Lys Pro Asp Ala Val Tyr Leu Gly Ile Tyr Glu Gly Leu Val 35 40 45 Leu Ala Gly Val His Glu Val Arg Asn Phe Trp His Ser Val Val Glu 50 55 60 Cys His Ala Val Tyr Asp Pro Gly Phe Arg Gly Glu Tyr Ala Leu Gln 65 70 75 80 Gly His Arg Leu Phe Cys Lys Trp Leu Leu Glu Asn Ser Pro Phe Leu 85 90 95 Asn Ser Ile Thr Met Val Pro Asp Thr Thr Lys Tyr Gly Arg Ala Ile 100 105 110 Ile Arg Leu Leu Gly Ala Thr Arg Val Gly His Leu Asp Asp Ala Tyr 115 120 125 Met Ser Asn Gly Lys Pro Val Gly Ile Thr Leu Tyr Gln Leu Pro Arg 130 135 140 Ser Lys Tyr Glu Glu Leu Leu Asn Val Ser Thr * 145 150 155 <210> 1292 <211> 96 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2455..2742) <400> 1292 Met Val Val Phe Asn Glu Asn Lys Thr Leu Phe Phe Lys Leu Ser Ile 1 5 10 15 Val Gly Thr Trp Pro Ser Gly Thr Ala Asn Arg Ser Met Gln Leu Thr 20 25 30 Phe Ser Gly Ser Val Pro Asp Thr Leu Val Ser Ser Arg Asn Ser Ala 35 40 45 Thr Thr Thr Asp Asn Ile Leu Leu Ala Thr Phe Phe Ser Val Asp Lys 50 55 60 Asp Gly Phe Leu Ala Thr Asn Gly Ser Thr Leu Thr Ile Gln Ser Asn 65 70 75 80 Gly Ala Ala Phe Thr Ala Thr Thr Ile Lys Ile Ile Ala Glu Gln * 85 90 95 <210> 1293 <211> 232 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3007..3702) <400> 1293 Met Glu Trp Ala Gln His Gln Ser Glu Pro His Val His Ala Ile Ile 1 5 10 15 Met Val Asn Glu Arg Ser Ile Asn Gly Gln Ala Gly Lys Ile Val Ser 20 25 30 Lys Trp Val Thr Leu Ala Asn Asn Ala Ile Pro Ser Asn Val Pro Pro 35 40 45 Gln Trp Asp Leu Asp Leu Lys Gly Gln Gln Tyr Ser Glu Pro Thr Lys 50 55 60 Cys Ile Gly Lys Gln Ile Asp Tyr Met Ala Lys Pro Glu Thr Lys Leu 65 70 75 80 Asn Asp Phe Asn Arg Glu Ala Ser Lys Ser Leu Tyr Asp Trp Ser Asp 85 90 95 Ala Asn Val Trp Gly Tyr Ser Asn Gly Trp Ala Arg His Glu Ile Lys 100 105 110 Lys Glu Thr Leu Ser Ile Thr Gly Phe His Ala Val Arg Arg Ile Leu 115 120 125 Lys Ala Val Gln Ala Ser Arg Lys Asp Asn Tyr Lys Ala Lys Arg Gln 130 135 140 Ile Gln Arg Thr Leu Lys Arg Gln Asp Ile Asn Arg Ser Pro Ile Thr 145 150 155 160 Pro Phe Gln Ala Pro Leu Ile Ser Lys His Asp Trp Asp Leu Ser Val 165 170 175 Ile Ala Val Thr Lys Glu Ala Glu Thr Glu Arg Arg Glu Leu Leu Ser 180 185 190 Ser Gln Ile Ile Asn Ser Asn Lys Val Gln Thr His Pro Leu Leu Arg 195 200 205 Met Leu Arg Arg Ala Arg Val Arg Ala Ser Arg Ala Lys Arg Glu Ser 210 215 220 Gly Gly Tyr Asp His Tyr Tyr * 225 230 <210> 1294 <211> 53 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3756..3914) <400> 1294 Met Pro Ala Lys Pro Pro Lys Ala Arg Ser Ala Ala Asn Ala Ala Arg 1 5 10 15 Gly Ala Arg Arg Arg Thr Tyr Pro Leu Lys Arg Ser Glu Ala His Arg 20 25 30 Ala Arg Arg Pro Lys Ser Pro Leu Thr Pro Leu Thr Lys Asp Gln Ser 35 40 45 Leu Arg Lys Lys * 50 <210> 1295 <211> 471 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4372..5784) <400> 1295 Met Ser Tyr Ala Leu Ile Asp Asn Ala Ser Leu Thr Ala Val Glu Arg 1 5 10 15 Thr Leu Gly Asp Ile Leu Val Lys Asn Pro Asp Thr Ile Asn Gly Asp 20 25 30 Leu Val Ala Phe Glu Asn Leu Ile Gln Ala Ile Leu Phe Tyr Asp Thr 35 40 45 Leu Ile Cys Val Asp Asn Tyr Lys Lys Glu Tyr Arg Asp Lys Arg Ile 50 55 60 Ala Lys Phe Asp Phe Ile Lys Phe Val Ser Glu Ser Asp Phe Gln Leu 65 70 75 80 Ser Glu Leu Asp Gln Leu Ala Gln Val Glu Ser Arg Gln Ile Thr Ser 85 90 95 Glu Ile Arg Gly Gly Glu Phe Val Asp Asp Asp Phe Arg Gln Leu Val 100 105 110 Glu Met Leu Lys Leu Asn Met Ile Cys Thr Trp Asp Leu Arg Ser Ser 115 120 125 Val Tyr Tyr Leu Thr Met Lys Met Leu Gly Gln Pro Gly Thr Pro Glu 130 135 140 Tyr Ala Lys Tyr Ser Glu Leu Ser Ala Ser Ile Phe Asn Glu Leu Ser 145 150 155 160 Asp Ala Ser Asp Thr Lys Gly Tyr Trp Ser Thr Asp Val Lys Leu Val 165 170 175 Ser Ser Ser Gly His Glu Tyr Thr Glu Arg Glu Phe Glu Leu Glu Arg 180 185 190 Glu Lys Ser Thr Arg Gly Lys Gly Gly Met Thr Arg Ser Leu Glu Met 195 200 205 Phe Ile Ala Ser Leu Asn Trp Leu Ala Tyr Lys Ser Ile Tyr Tyr Ser 210 215 220 Val Ile Ala Lys His Phe Lys Ala Asp Ser Phe Ile His Pro Ile Arg 225 230 235 240 His Ala Tyr Gln Leu His Trp Met Lys Lys Thr Gly Ala Phe Gly His 245 250 255 Asp Tyr Thr Ala Arg Leu Val Gln Ser Leu Ser Asp Lys Ile Ser Thr 260 265 270 Ala Arg Ser Glu Ile Val Asp His Gly Arg Thr Ser Thr Ile Ser Leu 275 280 285 Asp Leu Pro Ile Phe Ser Ala Trp Leu Ala Asn Glu Thr Gly Asn Val 290 295 300 Ser Gln Val Ile Asn Ser Ala Leu Glu Leu Arg Thr His Asp His Phe 305 310 315 320 Arg Thr Cys Arg Asp Val Ile Arg Glu Ile His Val Thr Tyr Asp Glu 325 330 335 Ser Gly Ile Ser Ala Gly Asn Lys Lys Val Thr Lys Leu Leu Ser Asp 340 345 350 Leu Asp Lys Ile Ser Gly Asp Ile Lys Arg Ser Tyr Gly Val Pro Ser 355 360 365 Asn Gln Gly Ile Gln Gly Ser Phe Leu Ile Lys Cys Ile Asn Ser Leu 370 375 380 Thr Gly Leu Val Gly Ile Pro Gly Leu Pro Asp Lys Glu Phe Ala Leu 385 390 395 400 Ser Thr Pro Glu Phe Met Lys Ser Lys Gln His Lys Ala Phe Ser Thr 405 410 415 Val Phe Lys Asp Val Thr Asn Glu Leu Thr Ser Ile Glu Arg Leu Gly 420 425 430 Gly Leu Arg Asp Lys Leu Ala Ser Asn Phe Thr Ile Asp Asp Ser Tyr 435 440 445 Tyr Thr Glu Pro Lys Thr Glu Asp Pro Arg Phe Arg Tyr Val Ser Ser 450 455 460 Asn Trp Lys Gln Pro Met * 465 470 <210> 1296 <211> 59 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5971..6147) <400> 1296 Met Glu Lys Asp Leu Lys Glu Leu Arg Glu Tyr Leu Leu Leu Ser Pro 1 5 10 15 Val Tyr Ser Glu Ile Asn Asp Cys Leu Ala Ser Leu Ser Met Glu Asp 20 25 30 Val Thr Asn Glu Glu Phe Ala Glu Arg Leu Gly Ile Ala Pro Asp Trp 35 40 45 Met Asp Ala Ile Asp Thr Ser Gln Leu Ala * 50 55 <210> 1297 <211> 209 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6450..7076) <400> 1297 Met Asn Val Arg Ile Tyr Cys Arg Ala Ser Thr Glu Gly Gln His Ala 1 5 10 15 Asp Arg Ala Leu Thr Ser Leu Arg Glu Phe Ser Lys Ser Lys Gly Trp 20 25 30 Gln Ile Ala Gly Glu Tyr Ile Glu Asn Ala Ser Gly Ala Lys Leu Glu 35 40 45 Arg Val Glu Leu Met Arg Leu Leu Ser Glu Ala Gln Ser Gly Asp Leu 50 55 60 Leu Leu Val Glu Ala Ile Asp Arg Leu Ser Arg Leu Glu His Ser Ala 65 70 75 80 Trp Val Glu Leu Lys Asp Thr Leu Asn Arg Lys Gly Leu Ile Ile Val 85 90 95 Ser Met Asp Leu Pro Thr Ser Trp Gln Met Val Glu Met Ala Gly Asn 100 105 110 Asp Leu Thr Ser Gly Ile Leu Arg Ala Val Asn Ala Met Leu Ile Asp 115 120 125 Ile Leu Ala Thr Met Ala Arg Gln Asp Tyr Glu Thr Arg Arg Lys Arg 130 135 140 Gln Gln Gln Gly Ile Glu Arg Ala Lys Ser Glu Gly Ile Tyr Ile Gly 145 150 155 160 Arg Ala Lys Asn Gln Glu Ala Arg Glu Ile Val Arg Glu Met Leu Glu 165 170 175 Gln Gly Val Lys Pro Glu Leu Ile Met Lys Ala Ala Gly Ile Ser Arg 180 185 190 Ala Thr Tyr Tyr Arg Ile Lys Asn Glu Leu Leu Ile Val Lys Ser Glu 195 200 205 * <210> 1298 <211> 416 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7674..8921) <400> 1298 Met Ala Leu Asn Ile Pro Phe Arg Asn Ala Tyr Tyr Arg Phe Ala Ser 1 5 10 15 Ser Tyr Ser Phe Leu Phe Phe Ile Ser Trp Ser Leu Trp Trp Ser Leu 20 25 30 Tyr Ala Ile Trp Leu Lys Gly His Leu Gly Leu Thr Gly Thr Glu Leu 35 40 45 Gly Thr Leu Tyr Ser Val Asn Gln Phe Thr Ser Ile Leu Phe Met Met 50 55 60 Phe Tyr Gly Ile Val Gln Asp Lys Leu Gly Leu Lys Lys Pro Leu Ile 65 70 75 80 Trp Cys Met Ser Phe Ile Leu Val Leu Thr Gly Pro Phe Met Ile Tyr 85 90 95 Val Tyr Glu Pro Leu Leu Gln Ser Asn Phe Ser Val Gly Leu Ile Leu 100 105 110 Gly Ala Leu Phe Phe Gly Leu Gly Tyr Leu Ala Gly Cys Gly Leu Leu 115 120 125 Asp Ser Phe Thr Glu Lys Met Ala Arg Asn Phe His Phe Glu Tyr Gly 130 135 140 Thr Ala Arg Ala Trp Gly Ser Phe Gly Tyr Ala Ile Gly Ala Phe Phe 145 150 155 160 Ala Gly Ile Phe Phe Ser Ile Ser Pro His Ile Asn Phe Trp Leu Val 165 170 175 Ser Leu Phe Gly Ala Val Phe Met Met Ile Asn Met Cys Phe Lys Asp 180 185 190 Lys Asp His Gln Cys Val Ala Ala Asp Ala Gly Gly Val Lys Lys Glu 195 200 205 Asp Phe Ile Ala Val Phe Lys Asp Arg Asn Phe Trp Val Phe Val Ile 210 215 220 Phe Ile Val Gly Thr Trp Ser Phe Tyr Asn Ile Phe Asp Gln Gln Leu 225 230 235 240 Phe Pro Val Phe Tyr Ala Gly Leu Phe Glu Ser His Asp Val Gly Thr 245 250 255 Arg Leu Tyr Gly Tyr Leu Asn Ser Phe Gln Val Val Leu Glu Ala Leu 260 265 270 Cys Met Ala Ile Ile Pro Phe Phe Val Asn Arg Val Gly Pro Lys Asn 275 280 285 Ala Leu Leu Ile Gly Val Val Ile Met Ala Leu Arg Ile Leu Ser Cys 290 295 300 Ala Leu Phe Val Asn Pro Trp Ile Ile Ser Leu Val Lys Leu Leu His 305 310 315 320 Ala Ile Glu Val Pro Leu Cys Val Ile Ser Val Phe Lys Tyr Ser Val 325 330 335 Ala Asn Phe Asp Lys Arg Leu Ser Ser Thr Ile Phe Leu Ile Gly Phe 340 345 350 Gln Ile Ala Ser Ser Leu Gly Ile Val Leu Leu Ser Thr Pro Thr Gly 355 360 365 Ile Leu Phe Asp His Ala Gly Tyr Gln Thr Val Phe Phe Ala Ile Ser 370 375 380 Gly Ile Val Cys Leu Met Leu Leu Phe Gly Ile Phe Phe Leu Ser Lys 385 390 395 400 Lys Arg Glu Gln Ile Val Met Glu Thr Pro Val Pro Ser Ala Ile * 405 410 415 <210> 1299 <211> 305 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8993..9907) <400> 1299 Met Ser Ala Lys Val Trp Val Leu Gly Asp Ala Val Val Asp Leu Leu 1 5 10 15 Pro Glu Ser Asp Gly Arg Leu Leu Pro Cys Pro Gly Gly Ala Pro Ala 20 25 30 Asn Val Ala Val Gly Ile Ala Arg Leu Gly Gly Thr Ser Gly Phe Ile 35 40 45 Gly Arg Val Gly Asp Asp Pro Phe Gly Ala Leu Met Gln Arg Thr Leu 50 55 60 Leu Thr Glu Gly Val Asp Ile Thr Tyr Leu Lys Gln Asp Glu Trp His 65 70 75 80 Arg Thr Ser Thr Val Leu Val Asp Leu Asn Asp Gln Gly Glu Arg Ser 85 90 95 Phe Thr Phe Met Val Arg Pro Ser Ala Asp Leu Phe Leu Glu Thr Thr 100 105 110 Asp Leu Pro Cys Trp Arg His Gly Glu Trp Leu His Leu Cys Ser Ile 115 120 125 Ala Leu Ser Ala Glu Pro Ser Arg Thr Ser Ala Phe Thr Ala Met Thr 130 135 140 Glu Ile Arg His Ala Gly Gly Phe Val Ser Phe Asp Pro Asn Ile Arg 145 150 155 160 Glu Asp Leu Trp Gln Asp Glu His Leu Leu Arg Leu Cys Leu Arg Gln 165 170 175 Ala Leu Gln Leu Ala Asp Val Val Lys Leu Ser Glu Glu Glu Trp Arg 180 185 190 Leu Ile Ser Gly Lys Thr Gln Asn Asp Arg Asp Ile Cys Ala Leu Ala 195 200 205 Lys Glu Tyr Glu Ile Ala Met Leu Leu Val Thr Lys Gly Ala Glu Gly 210 215 220 Val Val Val Cys Tyr Arg Gly Gln Val His His Phe Ala Gly Met Ser 225 230 235 240 Val Asp Cys Val Asp Ser Thr Gly Ala Gly Asp Ala Phe Val Ala Gly 245 250 255 Leu Leu Thr Gly Leu Ser Ser Thr Gly Leu Ser Thr Asp Glu Arg Glu 260 265 270 Met Arg Arg Ile Ile Asp Leu Ala Gln Arg Cys Gly Ala Leu Ala Val 275 280 285 Thr Ala Lys Gly Ala Met Thr Ala Leu Pro Cys Arg Gln Glu Leu Glu 290 295 300 * <210> 1300 <211> 478 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(10123..11556) <400> 1300 Met Thr Gln Ser Arg Leu His Ala Ala Gln Asn Ala Leu Ala Lys Leu 1 5 10 15 His Glu Arg Arg Gly Asn Thr Phe Tyr Pro His Phe His Leu Ala Pro 20 25 30 Pro Ala Gly Trp Met Asn Asp Pro Asn Gly Leu Ile Trp Phe Asn Asp 35 40 45 Arg Tyr His Ala Phe Tyr Gln His His Pro Met Ser Glu His Trp Gly 50 55 60 Pro Met His Trp Gly His Ala Thr Ser Asp Asp Met Ile His Trp Gln 65 70 75 80 His Glu Pro Ile Ala Leu Ala Pro Gly Asp Glu Asn Asp Lys Asp Gly 85 90 95 Cys Phe Ser Gly Ser Ala Val Asp Asp Asn Gly Val Leu Ser Leu Ile 100 105 110 Tyr Thr Gly His Val Trp Leu Asp Gly Ala Gly Asn Asp Asp Ala Ile 115 120 125 Arg Glu Val Gln Cys Leu Ala Thr Ser Arg Asp Gly Ile His Phe Glu 130 135 140 Lys Gln Gly Val Ile Leu Thr Pro Pro Glu Gly Ile Met His Phe Arg 145 150 155 160 Asp Pro Lys Val Trp Arg Glu Ala Asp Thr Trp Trp Met Val Val Gly 165 170 175 Ala Lys Asp Pro Gly Asn Thr Gly Gln Ile Leu Leu Tyr Arg Gly Ser 180 185 190 Ser Leu Arg Glu Trp Thr Phe Asp Arg Val Leu Ala His Ala Asp Ala 195 200 205 Gly Glu Ser Tyr Met Trp Glu Cys Pro Asp Phe Phe Ser Leu Gly Asp 210 215 220 Gln His Tyr Leu Met Phe Ser Pro Gln Gly Met Asn Ala Glu Gly Tyr 225 230 235 240 Ser Tyr Arg Asn Arg Phe Gln Ser Gly Val Ile Pro Gly Met Trp Ser 245 250 255 Pro Gly Arg Leu Phe Ala Gln Ser Gly His Phe Thr Glu Leu Asp Asn 260 265 270 Gly His Asp Phe Tyr Ala Pro Gln Ser Phe Val Ala Lys Asp Gly Arg 275 280 285 Arg Ile Val Ile Gly Trp Met Asp Met Trp Glu Ser Pro Met Pro Ser 290 295 300 Lys Arg Glu Gly Trp Ala Gly Cys Met Thr Leu Ala Arg Glu Leu Ser 305 310 315 320 Glu Ser Asn Gly Lys Leu Leu Gln Arg Pro Val His Glu Ala Glu Ser 325 330 335 Leu Arg Gln Gln His Gln Ser Ile Ser Pro Arg Thr Ile Ser Asn Lys 340 345 350 Tyr Val Leu Gln Glu Asn Ala Gln Ala Val Glu Ile Gln Leu Gln Trp 355 360 365 Ala Leu Lys Asn Ser Asp Ala Glu His Tyr Gly Leu Gln Leu Gly Thr 370 375 380 Gly Met Arg Leu Tyr Ile Asp Asn Gln Ser Glu Arg Leu Val Leu Trp 385 390 395 400 Arg Tyr Tyr Pro His Glu Asn Leu Asp Gly Tyr Arg Ser Ile Pro Leu 405 410 415 Pro Gln Arg Asp Thr Leu Ala Leu Arg Ile Phe Ile Asp Thr Ser Ser 420 425 430 Val Glu Val Phe Ile Asn Asp Gly Glu Ala Val Met Ser Ser Arg Ile 435 440 445 Tyr Pro Gln Pro Glu Glu Arg Glu Leu Ser Leu Tyr Ala Ser His Gly 450 455 460 Val Ala Val Val Gln His Gly Ala Leu Trp Gln Leu Gly * 465 470 475 <210> 1301 <211> 332 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(11564..12559) <400> 1301 Met Ala Ser Leu Lys Asp Val Ala Arg Leu Ala Gly Val Ser Met Met 1 5 10 15 Thr Val Ser Arg Val Met His Asn Ala Glu Ser Val Arg Pro Ala Thr 20 25 30 Arg Asp Arg Val Leu Gln Ala Ile Gln Thr Leu Asn Tyr Val Pro Asp 35 40 45 Leu Ser Ala Arg Lys Met Arg Ala Gln Gly Arg Lys Pro Ser Thr Leu 50 55 60 Ala Val Leu Ala Gln Asp Thr Ala Thr Thr Pro Phe Ser Val Asp Ile 65 70 75 80 Leu Leu Ala Ile Glu Gln Thr Ala Ser Glu Phe Gly Trp Asn Ser Phe 85 90 95 Leu Ile Asn Ile Phe Ser Glu Asp Asp Ala Ala Arg Ala Ala Arg Gln 100 105 110 Leu Leu Ala His Arg Pro Asp Gly Ile Ile Tyr Thr Thr Met Gly Leu 115 120 125 Arg His Ile Thr Leu Pro Glu Ser Leu Tyr Gly Glu Asn Ile Val Leu 130 135 140 Ala Asn Cys Val Ala Asp Asp Pro Ala Leu Pro Ser Tyr Ile Pro Asp 145 150 155 160 Asp Tyr Thr Ala Gln Tyr Glu Ser Thr Gln His Leu Leu Ala Ala Gly 165 170 175 Tyr Arg Gln Pro Leu Cys Phe Trp Leu Pro Glu Ser Ala Leu Ala Thr 180 185 190 Gly Tyr Arg Arg Gln Gly Phe Glu Gln Ala Trp Arg Asp Ala Gly Arg 195 200 205 Asp Leu Ala Glu Val Lys Gln Phe His Met Ala Thr Gly Asp Asp His 210 215 220 Tyr Thr Asp Leu Ala Ser Leu Leu Asn Asp His Phe Lys Ser Gly Lys 225 230 235 240 Pro Asp Phe Asp Val Leu Ile Cys Gly Asn Asp Arg Ala Ala Phe Val 245 250 255 Ala Tyr Gln Val Leu Leu Ala Lys Gly Val Arg Ile Pro Gln Asp Val 260 265 270 Ala Val Met Gly Phe Asp Asn Leu Val Gly Val Gly His Leu Phe Leu 275 280 285 Pro Pro Leu Thr Thr Ile Gln Leu Pro His Asp Ile Ile Gly Arg Glu 290 295 300 Ala Ala Leu His Ile Ile Glu Gly Arg Glu Gly Gly Ser Val Thr Arg 305 310 315 320 Ile Pro Cys Pro Leu Leu Ile Arg Cys Ser Thr * 325 330 <210> 1302 <211> 11515 <212> DNA <213> Escherichia coli O157:H7 <400> 1302 acaaaagcgt ggtgtcaagg aggggaggtt aacgtcatag tgaagaggag tggtggcacc 60 gatcaggtca tgatgtagtg gaagtgcctg gaggtgagca ggcagggcaa gattacgaaa 120 gcccgctccc cgcaaagact gacgccagat agtttctgtc catggctgct tttcgcatct 180 tacgtcttaa ccctgccttg aataccttat cattcgtcaa aatattaata gcaatgtgcc 240 gtatccctga aaataattct gctgcatttc ctcttcttat tttgcagtcg tcttcattca 300 ctaccacgtc cagacgccag tgcagcttat tctccacgtg ccagtggttt cggattgctg 360 tggcgaactt ctctgcggtt aaatcagcag aactgatata atatctgacc gtcatttctg 420 actctttctt ttgttctgct attatggacc gaaaggagac tgccacgcat aatttcttca 480 gccctttcca ttcaaacgtg aaatcaataa gttcatcagg gacatcgcaa acaatatgaa 540 gacggatttc ttctctgccg tgactctttt cactcattgc gtaactgtca tgctctggat 600 tatttaattc tttcagcgga aatttttcct caaaggcttt atttagccgc ccctggtttc 660 cttttaccgc gaataaataa tcacctccct gtttttgtat cttctctgca atatctttct 720 ggcaacccat cgcatcagtt gtgatgattt ttcctttaat atccagcatg ttaagaagtt 780 ctgggatagc tgtaatctca ttagatttct catccgtctt gatctgtccg atgaccagac 840 tgtgcattgt tgagaacgca ctaatgacat gaatcgctct cctgcggcga ctcttgtcat 900 aagagtgccg gagcgttttt ccatcaattg caatgacgtc tttatcatct gaagaatggc 960 agtcacgcat ccagttaata aagcactcgt gaaattttgc aggactgata caggatacaa 1020 ctctggcaat ggtatcgtga acaggaatac cattttcaaa atcaccatat tgcttcaaaa 1080 aattgagatg tgtttcccct aaatcctcta tatcttccca gccttctgca ccagaaatga 1140 cggcacaaat agtcaacagt agaatatccg ataatttatg ttccactttc caggcttgtc 1200 tgtaatcagg gataatagaa atatgttcca tcaatttttt aagttccatt ttgttctcct 1260 taattatgta aggagtattt gatcatatgt aagctgtgaa aaacagtttt agataataag 1320 gaatatctca attattgaac atttagtgcg aattatttag tacaaaaaag cggcgttagg 1380 tgatctttcc ctggcctctg tgcgatgtac gccagcggtc tgtaaagaaa ccgaacacct 1440 tataacaaaa cctctaacgt agtttataat acatcaggaa tattaataaa accttctggg 1500 tcagatatct caataaatat catatcaggc tcaaaagttt cagggacttt taatttcgct 1560 gaaattaacc aaccttgctt agaaccaata ctaatagatt tatagctgta attggcatgt 1620 agactatttt taatataagg aatttccctt aactctaact cacgccgagc caagtcaaga 1680 gccatttcga tagttatttt gttatgtttt atcaatttat tagtcccatc atgaattttt 1740 ctctcaatcc ctcaacatat tttatggcat gagctatttc cgcttcattg aataaatttt 1800 tactttttaa tatttcattt agaacgtgtt cctccctaga taaacgtcct agtgcttcgt 1860 atgcttctcg tccaattttc gcaaattgct tagcatgaat cacttcatga tacacctcat 1920 ataaggtagc atttttccta agataaatat tgcgaagacc ataatcaaaa gctgccctag 1980 catttggtgg caaatattta tctgctttcc ttattacttt aattcctagc ttctccattt 2040 ctttagcaat attgtttatt tgactacgtg ataaacgaac cccatccagg aaacccgtat 2100 gcccactaac acgacgacca tcgccaatat agtccatcaa actgctgatt ttagaacttg 2160 cagccaatcc cagcggatca acccacccac aaggattcgg cacataccgg taagtctgct 2220 cccctccctg caaccccagt ggatcactca ccaggtacat cccggtttcc ggctcgtaat 2280 atcggaaccg gttatagcac aaccccgatt ctgcatcctg ccactgtcct gcatacagca 2340 ggccggggtc ggcttccgcg tcccgctccc cgcgcgggtc cgggtagtct gtgtctgcgg 2400 gcaggctgag tgccagcccc cacaggctgg tctgtcccgg ccgccagacg gttttacctt 2460 cactgttaaa gagcatcagc ggacggcccg tcaggtcgtt caccgcatga ttcgttcgtg 2520 tcacccactg cggggccacg gacgggtgcg gctgccgtac ccggctgcac tgctggctta 2580 tcagctcaaa gccgttaaac accaggtgcc gtacgctgta cagttcatca tcgcggtatt 2640 cccggatttc cgcaatactg tcgccgtccc acaggtacgt gaagcggatt ttcttccggt 2700 cgcagcgttt ctctgttcgt ctgccgctgg cgtcgtggcg gtattcccac tgctcaccct 2760 gtgcgctgca atacccggtc agctggtccc ggctgtccca ccggaaccgc tctgtttccg 2820 ggcgatagcc gtcacggtgt ctggtgcggc tgaccatccg gcctgcggcg tcatagtcat 2880 actgcgtgtt tccggcctgt ttcagccggt ggcctccggc atactggtca gtctcttcac 2940 ttatccggtg cccgcccgca gactgcgcct tcaggtagcc acagctgtca tagccatagg 3000 actcatcgcc ttcgccatag cccagcccgg tgcctgaggc tgtcaccgcc gtgacctggc 3060 cgttccggtc aagccggtac tcccgctgtg tttcccgtcc gtaatcttcc cggctggtga 3120 cgcctgatac gttacccgcg ctgtcgtaac ggtactcccg tatcagtgag gggagcagta 3180 ttccccatgt ggcctctttc ggggaatatt ttccttacca agaaatatct attatttttt 3240 tatttttcca tctccaagca ttatatttgt ttgtcacggg gaataattca tggccaaaac 3300 cttccccttg ccaaaacaat ctccccgtta aaataaatcc actgtaatta ttaattaaat 3360 cataaatcac agattcaatt acaaatctat aacgaccatc gtgaaatgtt tttagtatta 3420 acaccctgat agtgcaagtt gctttttgtt taccatctac atcattaaaa atcatactac 3480 cctttatttc atcagcagca tcttttattt tgcatgtgta atttaattct attttttttc 3540 cagactggct agaaagatcg agtaggtaag gtttaattaa aagctgataa atattttcat 3600 ataataaatc aatctctttc atattgccgc cttattgttt tataaccgaa agtcgttaat 3660 atcaatccca ccaaacacat ctgaatatat atccactgct gatggttttg ttttattaag 3720 tgttatatca aatccttcaa taactggatg taatccatat tggtttgtag gagatgtgat 3780 atcaataata ccggcatcta gacgtttgga accacctgta taatgagtgc cggatgtcca 3840 cttaccattt actttaaatg gtccattcgt tgtcgcagga actcgctctc cattttttat 3900 ggctggttga atctcaactc taaatttact acctgttaat tctagtcttt tatttatcat 3960 gtttatgtat ttattgaatg cagcctctga ttttatccaa tcaccattag catatttaag 4020 tgctctattc cctaatgagt tcaaaacatc agatatgttg ctttgctcac tcccccattt 4080 cgtccagcgg gctaactgac atatagccag ccccaaagga tcgatatacc cacaaggatt 4140 cggcacatac cgataagtct gctcccctcc ctgcaacccc agcggatcac tcaccaggta 4200 catcccggtt tccggctcgt agtaccggaa ccggttatag cacagccccg attctgcatc 4260 ctgccactgt cccgcataca gcaggccggg gtccgcttcc gggtcccgct ccccgcgcgg 4320 gtccgggtag tctgtgtctg cgggcaggct gagtgccagc ccccacaggc tggtctgccc 4380 cggccgccag acggttttac cttcactgtt aaagagcatc agcgggcggc ccgtcaggtc 4440 gctcaccgca tgattcgttc gcgtcaccca ctgcggggcc acggacggat gcggctgtcg 4500 tacccggctg aactgctggc ttatcagctc aaagccgtta aacaccaggt gccttacgct 4560 gtacagttta tcatcgcggt attcccggat ttccgcaata ctgtcgccgt cccacaggta 4620 cgtaaaacgg attttcttcc ggtcgcagcg tttttccgtc cgtctgccgc tggcgtcgtg 4680 gcggtattcc cactgctccc cctgtgcgct gcgatacccg gtcagctggt cccggctgtc 4740 ccaccggaac cgctctgttt ctgggcggta gccgtcacgg tgttttgtgc ggctgaccat 4800 ccggcctgcg gcgtcatagt catactgtgt gtttccggcc tgtttcagcc ggtggcctgc 4860 ggcatactgg tcagtctctc cgcttatccg gtgtctgccc gcagactgcg ccttcaggta 4920 gccgcagctg tcatagccat aagtctcgtc gccttcgcca tagcccagcc cggtgcctga 4980 ggctgtcacc gccgtgacct ggccgttccg gtcaagccgg tactcccggt gtgtttcccg 5040 tccgtaatct tcccggctgg tgacgcctga tacgttaccc gcgctgtcgt aacggtattc 5100 ccgtagcagt gaagggagca gtccgcccca tgtggcttcc gccgggaaaa gtccggcgcg 5160 ctggctgaca ggctgaccgg ctgcattcca gccctgttca caggcaaaac cccggttact 5220 gtgccggagc acttcacgtc ccgcctcatc acggctgaac gtcagcgtct catcccccgg 5280 caggataacc tccgtcagtt ctccggcggc gttgtagcgg tatgtggttt tcagcaggga 5340 tccgtcgggg tgtctgtcgc gttcatcttc cggtggcagg atacagcgga tgacggtgtg 5400 ttcgtcgggg tagtggtatt caatggcccg tcggccctga gtggtgacat tcacccgccc 5460 gcgttcatca tagccggtgc gctgtgatgt gccgtccggg ctgaagatac ccgtcagcct 5520 gccggatttg tcatacgcat actgcgtttt gccttccgga gtgatgactt ctgccaggcg 5580 gcctgcggca tcccggctgt agaggatggt ttcctccagg ccgttgaccc tggcggtaca 5640 caggccatca gcgtcataac ggtaacgaca gaccacgccg ccccagtcac gttcttccgt 5700 cacccggcca cagttgtcca gaatataaag ataagactcg ccctgcgggt taatgacttc 5760 tgtcagttgc agcgtgtctt tatcgtagcg gtactgccag cggtggcctt caccgtccgt 5820 tcgcgccacc ggcaaatcaa acgggccgta ctccattgtc cagacaacgc cgttaccgtc 5880 cgtgtacgcc agcaggttgc cgtggcggtc gtagcggaat ccttccgcgc cggttcctgc 5940 ccgctcaagg ccactcagtt tatggtgctg ctgccactgc aaccgcactg actgaccgcc 6000 ggggccgcgc atcttcaccg gcaggtcgtg accgctgtat tcggtgtggt gttcgcggcc 6060 catcacgtcg gtgagtgttt ccggccagtt gtggtggtcg tactctatgc ccagacgccg 6120 ttcatcctgg cggaatatcc ccgacagcag cccctgaggg gtgtacgcca gccgggtctc 6180 ttcgccctgt ggcgatacca gactcaccgg caggccgcgt tcatcacact gctgcgtcca 6240 cgtctgcccg gcaggggcgg tgatgttgct gagcaggccg cgctcatcat agcagtactg 6300 ccaatccgcg ccgtctgccg ccgtgtaacg gcttaactga ccgtgtgcgg cgttgtattc 6360 aaacttctcc acccgcccgg caggggagtg gcgggccagc aggtgatgga attcatccca 6420 ttcatacgtg gtggtgctgc cgtccggcgc ttcttcccgc agaatattgc cgtcaggatc 6480 atagtaataa cggtgaatgc ccttgccgtc cgtcacggtg gtgcagccgt caccatagtc 6540 cagcgtggcg ttgtaatagc cctccgcccc ggtgacggtc acgcaccggc cctgtgcatc 6600 gtaggtgaaa cggctccacg tctggtcgtt atcggaccag cggatgatcc ggtccgcagc 6660 gtcgtactca taaaacaggt ggtagtccag ccgcgcatcc tgttcgtagg tcgccagcgt 6720 ctgtatgccg ttatccgtgc ggtgaatggc tttcaggtag ccgctggcgt ggtacgtcag 6780 tttaagccgg atcccgtcgg tgtgactgac acccgtgatc cggtactggg tgtcgcgctc 6840 aaacgtgatg cggttgctgg cggtgtcgct catcccgccc agcatgtaca tccggtctgc 6900 ggggctgtgt gccaggcggt catcgctggt atcgtcagtc accgggtggc gcagacgcat 6960 tcccggaaag gcgtcataaa agaagcggct gctcagtgca tccctgtcga acagctccag 7020 ataatcatca cggcggcgca gaatgtactg ggcgtgatac gggttaaccg ccgtatcact 7080 ttcaccgtcg aaggcgaagt tcagcgtggc tcccaggctg atgacatcca cccggtttcc 7140 ctgttcacgc acccaggcgt attcgctcca ggagtcgctc cagcccacgc ccgtcaggcc 7200 atgcagcggc agtacagaac tgtggaaacg ggtgaaggag agggggagtg tctggcccag 7260 cgtaaagtcg gtacgttcgt cgcagtatgc gccggttacc ggatcgacag gatctgttac 7320 ccatctgatg actttattgg caatactttt taacgaatta cctgttttcc ccagcaacgc 7380 gccgagcttt gcgcccagca gcttaccgct tttccccagc aggtttccca gtttgcccag 7440 tttcgccaga ttccccagtt ttcccagcag tcctgctggc ggcagaagat agctggctat 7500 cgttattcct cccaggatca ttctctgcca tggcgggaac tccggctgga tatccagata 7560 ggtgacctgc tcacccccaa taaagacgtc cggcgaacct tccacgattg ccgcgctgca 7620 ctccagtttg tcgcccttgc gcgcggcagg ctgattgttg ataaagacgt tgctgctgcc 7680 ctgggctatc ctcggtggtt tgttctcctt gtcgcagagc gccgtgtcct caccggcttc 7740 cgggaaatcc acatcttttt tgatttcgcc acgcccgccc accatggtgg caaactccat 7800 taataccgga ccggcgggaa acagaagcga tgcgccggcg ctgacgcgat ccataaaacc 7860 ggcattgctg tccgtcaggg tgataacagc gttcccccag gccttcgcca gtggtactgc 7920 tttttccgct gccgattcaa gcaggtcagt ggcaatatca ccccatgagg gttccccctg 7980 tgggacttca ggtattgctc caggtggggg aggaggggga agggtgacgg ctgcacgggc 8040 tgctggcttt ccgttaattt ttacattttt agaaccggta ttgatggcgc cgtccgtgtc 8100 acaaaagctg tttatccatg attcaagctg gttctgtttc tcctccacat aatcactcgc 8160 cttatagctg gcatacatca gcgcaggcac cagaaccagc gcataagggc cggtggcaca 8220 ggcggccata atcaggcaac cttctgctat ggtcactatc gcccccagca cggcccctgc 8280 cagcgccccc aaaaaactct tgtgctgaat ttcatcgccc agcctggcgg cgggggggcc 8340 agactttttt gatgccaaca tctgtgcaat ggctttgtcg ttggctgccc gtttcatctg 8400 gctggcggcc atcgcccgct gcgacagcat ccgcattgcc agcgtaccgc ctgcggtcgc 8460 tccctgtggc ccgcctggtc cttcactcat gttttatccc tcgtttatgt cagcgcggct 8520 ggtccttttg gatgtcattc tccggtggca acggggtgaa gctctttatc acctccagca 8580 gcatcgtctt ttgactgttc ttcagggata aggaggtgct gaaagtgaag gtcagcagcg 8640 tatctccacg ccgctggaat acggctatct ggctaatccg cccctgattc ccttcatctt 8700 ccggaccgtt ccaggaataa tccagcagcc aggccggggc ctctgccaga gtgatttccc 8760 ggcaggcatg ttcggtgtac ccatcaagtt tgccctggta cagcgccagc gtttcctggt 8820 acagctctgg tgtcagggtt ccctgtgaaa cgggttcgcg ggtaatgacc aggttgatgc 8880 cactgttatc cgtggatacc aggacctgca tcgactgatc ctgccattgc gatggcagtt 8940 gaatatgacc ttcattaaaa gtgaactgca taaaatactc cctgttaatc tgagtgaatc 9000 agttgatgaa aacagaaccg cccacgatgg tgatgccatc cttcgacagc ctgattaccg 9060 ttgattcccc gacctgtagc tgaatgccat ccggcgtcag cgcaattttg ctttcctcca 9120 cggccagcat aatttcctta attgccgtat aagcctgtat accgttgcct tcgccaccat 9180 tgtttacagc gtcaacatgc accgaaccgg caatcgtgcc tctgtcctga aagacatcct 9240 cagataaaga ccctttcagt actccggtga tcttgtggcc tttttccacc gtaagaaggc 9300 ggttaccttc ctggatcgtg accgtctggt cattttttac ggtttcgcga tgatcgtgtt 9360 ttacggtggt ggtacggtcg ttgagcactt cggtatccat gttcttctgc gcgtggatgt 9420 agacctgttc tctccctgtc gcatcatcaa acttcagctc attaaacccg ctgcccatat 9480 acgttttgga acggatggtc atctgcgtct tcgtccccgg caggctgccg ggggtgcggt 9540 tttcctggtg gtaggtgcgc cccataatga tcggctggtc cggatcgccg ttgaggaagt 9600 ccactatcac ctcctgaccc acacgcggta tcgccaggtt gccaaaaccg gtgcctgccc 9660 acgcctgtgc cacacggatc cagcacgagc tgtcctggtc tgccgggtta taacggtccc 9720 agttgaattt cacccgcact cggccatgtt catcacagaa gatttcctca ccctccggcc 9780 ccgtcacgac ggcgctctgc ggaccgtcca ccagcggttt tagccgcggc tggggtcgcc 9840 atgtccggtc tgccgggatc accgcaaaat ggttctccag cgccgtccct gctccccgcc 9900 ttcccggcac cgcctgcggc tgctcgccgt gcagttcact tgccaccacc tgccattccc 9960 ggttcaggtt cgcctgcgga tgccccgtca gcacaattcg ccgtcccggc catatctccg 1002 0 gcgagcgact cattccccgc gcggtttctg cattgtttcg ccagccctcc atctgccagc 1008 0 gggcaaagtt ctgcccgtgg gcgcccttga aacgtccggg gtagtcatac acctcatact 1014 0 gcgtgcgctg gtaatcctgg tgctggcctt cctgatcaaa acgtcctgcc cagccggggc 1020 0 gtttaaaggt gtagtctttg gtcaccacgg aagaagggcg gatttgtgcg ctgtagcgaa 1026 0 actggctgat gcagagggtg ctcacctcgg tacgggtgtt cgggttccag gggatttcaa 1032 0 aagattcggg cagatggcgg accgtgtcgc acagcaccag gctctggtcg gtacttttgt 1038 0 aagcatgctc ctcataaaag aagatgcctt cctccgccgc catccggcac aggaaatcgt 1044 0 aatcagtctc accgtactgg acacaaaact cacgggaagg atgcggttca ctgaacagcg 1050 0 gactccactc ggtcaccccg ttttcctgca atatcgtgcc gaggatgctt ttgatgtcct 1056 0 cgttctggaa gatacggaag ttctggcgca gaccggcacg ccacagcggc gggtgcacct 1062 0 tcatgctgta cagcatctgg tttttgtcgt tctcccccag ttcaaaccag gtcaccacac 1068 0 ctttcacccg gcgctgtaca tcatcaccct gccatattgt caggtaggcc attttgtcca 1074 0 gcacctgcgc aaattcaagg gagagaaact gctggctgac caaggagaga tcgagggaaa 1080 0 agagcgaaga gagtgactgg gtgagatgaa aggaaaccac cgcaaaagcg tccggtggca 1086 0 ggccgtccac ttccagtgtg aaacgtaatc cggttgacat agcaacctcc ggtaaaatga 1092 0 ataataatcc gcaccgtaca actgcggata atgagataag cgggacgact taagacgtta 1098 0 ttagggaagg aacaaaaaat gctatgatta tgtgaggatt ttgtttaaat attactttac 1104 0 agaaacgggt gtctgttcag tcaaaaaaat aatcacaagc tcaacttatt gtttcctgac 1110 0 gttattcagg acaggtgcgc acatcacagc gagtaacaaa aacgcaaagt taaaccaata 1116 0 ttcataatat gtttttattc acaactaaat aacccaatta acatcattaa aatgaatgat 1122 0 tgcttaaaaa atatatgcta ccgctccacc ctgataacat gatctgcaca ttgcacatct 1128 0 taacgttgtt aaatactggc tcaatagtgg atattttaaa ttaggaattt atcaaattca 1134 0 ctttataaat ggattgggtg aataatataa aaattaatga tgattaatcg cgatttaatt 1140 0 attcattgct ttatatgata ggtggcttgt ttataatgat ggaaatttag cgaaaaacgc 1146 0 cgtaaaccct cgccctgaat ttgaacttaa taatcacccc ctctccggca acaca 1151 5 <210> 1303 <211> 379 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(113..1249) <400> 1303 Met Glu Leu Lys Lys Leu Met Glu His Ile Ser Ile Ile Pro Asp Tyr 1 5 10 15 Arg Gln Ala Trp Lys Val Glu His Lys Leu Ser Asp Ile Leu Leu Leu 20 25 30 Thr Ile Cys Ala Val Ile Ser Gly Ala Glu Gly Trp Glu Asp Ile Glu 35 40 45 Asp Leu Gly Glu Thr His Leu Asn Phe Leu Lys Gln Tyr Gly Asp Phe 50 55 60 Glu Asn Gly Ile Pro Val His Asp Thr Ile Ala Arg Val Val Ser Cys 65 70 75 80 Ile Ser Pro Ala Lys Phe His Glu Cys Phe Ile Asn Trp Met Arg Asp 85 90 95 Cys His Ser Ser Asp Asp Lys Asp Val Ile Ala Ile Asp Gly Lys Thr 100 105 110 Leu Arg His Ser Tyr Asp Lys Ser Arg Arg Arg Arg Ala Ile His Val 115 120 125 Ile Ser Ala Phe Ser Thr Met His Ser Leu Val Ile Gly Gln Ile Lys 130 135 140 Thr Asp Glu Lys Ser Asn Glu Ile Thr Ala Ile Pro Glu Leu Leu Asn 145 150 155 160 Met Leu Asp Ile Lys Gly Lys Ile Ile Thr Thr Asp Ala Met Gly Cys 165 170 175 Gln Lys Asp Ile Ala Glu Lys Ile Gln Lys Gln Gly Gly Asp Tyr Leu 180 185 190 Phe Ala Val Lys Gly Asn Gln Gly Arg Leu Asn Lys Ala Phe Glu Glu 195 200 205 Lys Phe Pro Leu Lys Glu Leu Asn Asn Pro Glu His Asp Ser Tyr Ala 210 215 220 Met Ser Glu Lys Ser His Gly Arg Glu Glu Ile Arg Leu His Ile Val 225 230 235 240 Cys Asp Val Pro Asp Glu Leu Ile Asp Phe Thr Phe Glu Trp Lys Gly 245 250 255 Leu Lys Lys Leu Cys Val Ala Val Ser Phe Arg Ser Ile Ile Ala Glu 260 265 270 Gln Lys Lys Glu Ser Glu Met Thr Val Arg Tyr Tyr Ile Ser Ser Ala 275 280 285 Asp Leu Thr Ala Glu Lys Phe Ala Thr Ala Ile Arg Asn His Trp His 290 295 300 Val Glu Asn Lys Leu His Trp Arg Leu Asp Val Val Val Asn Glu Asp 305 310 315 320 Asp Cys Lys Ile Arg Arg Gly Asn Ala Ala Glu Leu Phe Ser Gly Ile 325 330 335 Arg His Ile Ala Ile Asn Ile Leu Thr Asn Asp Lys Val Phe Lys Ala 340 345 350 Gly Leu Arg Arg Lys Met Arg Lys Ala Ala Met Asp Arg Asn Tyr Leu 355 360 365 Ala Ser Val Phe Ala Gly Ser Gly Leu Ser * 370 375 <210> 1304 <211> 445 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1712..3046) <400> 1304 Val Thr Ala Ser Gly Thr Gly Leu Gly Tyr Gly Glu Gly Asp Glu Ser 1 5 10 15 Tyr Gly Tyr Asp Ser Cys Gly Tyr Leu Lys Ala Gln Ser Ala Gly Gly 20 25 30 His Arg Ile Ser Glu Glu Thr Asp Gln Tyr Ala Gly Gly His Arg Leu 35 40 45 Lys Gln Ala Gly Asn Thr Gln Tyr Asp Tyr Asp Ala Ala Gly Arg Met 50 55 60 Val Ser Arg Thr Arg His Arg Asp Gly Tyr Arg Pro Glu Thr Glu Arg 65 70 75 80 Phe Arg Trp Asp Ser Arg Asp Gln Leu Thr Gly Tyr Cys Ser Ala Gln 85 90 95 Gly Glu Gln Trp Glu Tyr Arg His Asp Ala Ser Gly Arg Arg Thr Glu 100 105 110 Lys Arg Cys Asp Arg Lys Lys Ile Arg Phe Thr Tyr Leu Trp Asp Gly 115 120 125 Asp Ser Ile Ala Glu Ile Arg Glu Tyr Arg Asp Asp Glu Leu Tyr Ser 130 135 140 Val Arg His Leu Val Phe Asn Gly Phe Glu Leu Ile Ser Gln Gln Cys 145 150 155 160 Ser Arg Val Arg Gln Pro His Pro Ser Val Ala Pro Gln Trp Val Thr 165 170 175 Arg Thr Asn His Ala Val Asn Asp Leu Thr Gly Arg Pro Leu Met Leu 180 185 190 Phe Asn Ser Glu Gly Lys Thr Val Trp Arg Pro Gly Gln Thr Ser Leu 195 200 205 Trp Gly Leu Ala Leu Ser Leu Pro Ala Asp Thr Asp Tyr Pro Asp Pro 210 215 220 Arg Gly Glu Arg Asp Ala Glu Ala Asp Pro Gly Leu Leu Tyr Ala Gly 225 230 235 240 Gln Trp Gln Asp Ala Glu Ser Gly Leu Cys Tyr Asn Arg Phe Arg Tyr 245 250 255 Tyr Glu Pro Glu Thr Gly Met Tyr Leu Val Ser Asp Pro Leu Gly Leu 260 265 270 Gln Gly Gly Glu Gln Thr Tyr Arg Tyr Val Pro Asn Pro Cys Gly Trp 275 280 285 Val Asp Pro Leu Gly Leu Ala Ala Ser Ser Lys Ile Ser Ser Leu Met 290 295 300 Asp Tyr Ile Gly Asp Gly Arg Arg Val Ser Gly His Thr Gly Phe Leu 305 310 315 320 Asp Gly Val Arg Leu Ser Arg Ser Gln Ile Asn Asn Ile Ala Lys Glu 325 330 335 Met Glu Lys Leu Gly Ile Lys Val Ile Arg Lys Ala Asp Lys Tyr Leu 340 345 350 Pro Pro Asn Ala Arg Ala Ala Phe Asp Tyr Gly Leu Arg Asn Ile Tyr 355 360 365 Leu Arg Lys Asn Ala Thr Leu Tyr Glu Val Tyr His Glu Val Ile His 370 375 380 Ala Lys Gln Phe Ala Lys Ile Gly Arg Glu Ala Tyr Glu Ala Leu Gly 385 390 395 400 Arg Leu Ser Arg Glu Glu His Val Leu Asn Glu Ile Leu Lys Ser Lys 405 410 415 Asn Leu Phe Asn Glu Ala Glu Ile Ala His Ala Ile Lys Tyr Val Glu 420 425 430 Gly Leu Arg Glu Lys Phe Met Met Gly Leu Ile Asn * 435 440 <210> 1305 <211> 136 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3215..3622) <400> 1305 Met Lys Glu Ile Asp Leu Leu Tyr Glu Asn Ile Tyr Gln Leu Leu Ile 1 5 10 15 Lys Pro Tyr Leu Leu Asp Leu Ser Ser Gln Ser Gly Lys Lys Ile Glu 20 25 30 Leu Asn Tyr Thr Cys Lys Ile Lys Asp Ala Ala Asp Glu Ile Lys Gly 35 40 45 Ser Met Ile Phe Asn Asp Val Asp Gly Lys Gln Lys Ala Thr Cys Thr 50 55 60 Ile Arg Val Leu Ile Leu Lys Thr Phe His Asp Gly Arg Tyr Arg Phe 65 70 75 80 Val Ile Glu Ser Val Ile Tyr Asp Leu Ile Asn Asn Tyr Ser Gly Phe 85 90 95 Ile Leu Thr Gly Arg Leu Phe Trp Gln Gly Glu Gly Phe Gly His Glu 100 105 110 Leu Phe Pro Val Thr Asn Lys Tyr Asn Ala Trp Arg Trp Lys Asn Lys 115 120 125 Lys Ile Ile Asp Ile Ser Trp * 130 135 <210> 1306 <211> 1617 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3640..8490) <400> 1306 Met Ser Glu Gly Pro Gly Gly Pro Gln Gly Ala Thr Ala Gly Gly Thr 1 5 10 15 Leu Ala Met Arg Met Leu Ser Gln Arg Ala Met Ala Ala Ser Gln Met 20 25 30 Lys Arg Ala Ala Asn Asp Lys Ala Ile Ala Gln Met Leu Ala Ser Lys 35 40 45 Lys Ser Gly Pro Pro Ala Ala Arg Leu Gly Asp Glu Ile Gln His Lys 50 55 60 Ser Phe Leu Gly Ala Leu Ala Gly Ala Val Leu Gly Ala Ile Val Thr 65 70 75 80 Ile Ala Glu Gly Cys Leu Ile Met Ala Ala Cys Ala Thr Gly Pro Tyr 85 90 95 Ala Leu Val Leu Val Pro Ala Leu Met Tyr Ala Ser Tyr Lys Ala Ser 100 105 110 Asp Tyr Val Glu Glu Lys Gln Asn Gln Leu Glu Ser Trp Ile Asn Ser 115 120 125 Phe Cys Asp Thr Asp Gly Ala Ile Asn Thr Gly Ser Lys Asn Val Lys 130 135 140 Ile Asn Gly Lys Pro Ala Ala Arg Ala Ala Val Thr Leu Pro Pro Pro 145 150 155 160 Pro Pro Pro Gly Ala Ile Pro Glu Val Pro Gln Gly Glu Pro Ser Trp 165 170 175 Gly Asp Ile Ala Thr Asp Leu Leu Glu Ser Ala Ala Glu Lys Ala Val 180 185 190 Pro Leu Ala Lys Ala Trp Gly Asn Ala Val Ile Thr Leu Thr Asp Ser 195 200 205 Asn Ala Gly Phe Met Asp Arg Val Ser Ala Gly Ala Ser Leu Leu Phe 210 215 220 Pro Ala Gly Pro Val Leu Met Glu Phe Ala Thr Met Val Gly Gly Arg 225 230 235 240 Gly Glu Ile Lys Lys Asp Val Asp Phe Pro Glu Ala Gly Glu Asp Thr 245 250 255 Ala Leu Cys Asp Lys Glu Asn Lys Pro Pro Arg Ile Ala Gln Gly Ser 260 265 270 Ser Asn Val Phe Ile Asn Asn Gln Pro Ala Ala Arg Lys Gly Asp Lys 275 280 285 Leu Glu Cys Ser Ala Ala Ile Val Glu Gly Ser Pro Asp Val Phe Ile 290 295 300 Gly Gly Glu Gln Val Thr Tyr Leu Asp Ile Gln Pro Glu Phe Pro Pro 305 310 315 320 Trp Gln Arg Met Ile Leu Gly Gly Ile Thr Ile Ala Ser Tyr Leu Leu 325 330 335 Pro Pro Ala Gly Leu Leu Gly Lys Leu Gly Asn Leu Ala Lys Leu Gly 340 345 350 Lys Leu Gly Asn Leu Leu Gly Lys Ser Gly Lys Leu Leu Gly Ala Lys 355 360 365 Leu Gly Ala Leu Leu Gly Lys Thr Gly Asn Ser Leu Lys Ser Ile Ala 370 375 380 Asn Lys Val Ile Arg Trp Val Thr Asp Pro Val Asp Pro Val Thr Gly 385 390 395 400 Ala Tyr Cys Asp Glu Arg Thr Asp Phe Thr Leu Gly Gln Thr Leu Pro 405 410 415 Leu Ser Phe Thr Arg Phe His Ser Ser Val Leu Pro Leu His Gly Leu 420 425 430 Thr Gly Val Gly Trp Ser Asp Ser Trp Ser Glu Tyr Ala Trp Val Arg 435 440 445 Glu Gln Gly Asn Arg Val Asp Val Ile Ser Leu Gly Ala Thr Leu Asn 450 455 460 Phe Ala Phe Asp Gly Glu Ser Asp Thr Ala Val Asn Pro Tyr His Ala 465 470 475 480 Gln Tyr Ile Leu Arg Arg Arg Asp Asp Tyr Leu Glu Leu Phe Asp Arg 485 490 495 Asp Ala Leu Ser Ser Arg Phe Phe Tyr Asp Ala Phe Pro Gly Met Arg 500 505 510 Leu Arg His Pro Val Thr Asp Asp Thr Ser Asp Asp Arg Leu Ala His 515 520 525 Ser Pro Ala Asp Arg Met Tyr Met Leu Gly Gly Met Ser Asp Thr Ala 530 535 540 Ser Asn Arg Ile Thr Phe Glu Arg Asp Thr Gln Tyr Arg Ile Thr Gly 545 550 555 560 Val Ser His Thr Asp Gly Ile Arg Leu Lys Leu Thr Tyr His Ala Ser 565 570 575 Gly Tyr Leu Lys Ala Ile His Arg Thr Asp Asn Gly Ile Gln Thr Leu 580 585 590 Ala Thr Tyr Glu Gln Asp Ala Arg Leu Asp Tyr His Leu Phe Tyr Glu 595 600 605 Tyr Asp Ala Ala Asp Arg Ile Ile Arg Trp Ser Asp Asn Asp Gln Thr 610 615 620 Trp Ser Arg Phe Thr Tyr Asp Ala Gln Gly Arg Cys Val Thr Val Thr 625 630 635 640 Gly Ala Glu Gly Tyr Tyr Asn Ala Thr Leu Asp Tyr Gly Asp Gly Cys 645 650 655 Thr Thr Val Thr Asp Gly Lys Gly Ile His Arg Tyr Tyr Tyr Asp Pro 660 665 670 Asp Gly Asn Ile Leu Arg Glu Glu Ala Pro Asp Gly Ser Thr Thr Thr 675 680 685 Tyr Glu Trp Asp Glu Phe His His Leu Leu Ala Arg His Ser Pro Ala 690 695 700 Gly Arg Val Glu Lys Phe Glu Tyr Asn Ala Ala His Gly Gln Leu Ser 705 710 715 720 Arg Tyr Thr Ala Ala Asp Gly Ala Asp Trp Gln Tyr Cys Tyr Asp Glu 725 730 735 Arg Gly Leu Leu Ser Asn Ile Thr Ala Pro Ala Gly Gln Thr Trp Thr 740 745 750 Gln Gln Cys Asp Glu Arg Gly Leu Pro Val Ser Leu Val Ser Pro Gln 755 760 765 Gly Glu Glu Thr Arg Leu Ala Tyr Thr Pro Gln Gly Leu Leu Ser Gly 770 775 780 Ile Phe Arg Gln Asp Glu Arg Arg Leu Gly Ile Glu Tyr Asp His His 785 790 795 800 Asn Trp Pro Glu Thr Leu Thr Asp Val Met Gly Arg Glu His His Thr 805 810 815 Glu Tyr Ser Gly His Asp Leu Pro Val Lys Met Arg Gly Pro Gly Gly 820 825 830 Gln Ser Val Arg Leu Gln Trp Gln Gln His His Lys Leu Ser Gly Leu 835 840 845 Glu Arg Ala Gly Thr Gly Ala Glu Gly Phe Arg Tyr Asp Arg His Gly 850 855 860 Asn Leu Leu Ala Tyr Thr Asp Gly Asn Gly Val Val Trp Thr Met Glu 865 870 875 880 Tyr Gly Pro Phe Asp Leu Pro Val Ala Arg Thr Asp Gly Glu Gly His 885 890 895 Arg Trp Gln Tyr Arg Tyr Asp Lys Asp Thr Leu Gln Leu Thr Glu Val 900 905 910 Ile Asn Pro Gln Gly Glu Ser Tyr Leu Tyr Ile Leu Asp Asn Cys Gly 915 920 925 Arg Val Thr Glu Glu Arg Asp Trp Gly Gly Val Val Cys Arg Tyr Arg 930 935 940 Tyr Asp Ala Asp Gly Leu Cys Thr Ala Arg Val Asn Gly Leu Glu Glu 945 950 955 960 Thr Ile Leu Tyr Ser Arg Asp Ala Ala Gly Arg Leu Ala Glu Val Ile 965 970 975 Thr Pro Glu Gly Lys Thr Gln Tyr Ala Tyr Asp Lys Ser Gly Arg Leu 980 985 990 Thr Gly Ile Phe Ser Pro Asp Gly Thr Ser Gln Arg Thr Gly Tyr Asp 995 1000 1005 Glu Arg Gly Arg Val Asn Val Thr Thr Gln Gly Arg Arg Ala Ile Glu 1010 1015 1020 Tyr His Tyr Pro Asp Glu His Thr Val Ile Arg Cys Ile Leu Pro Pro 1025 1030 1035 1040 Glu Asp Glu Arg Asp Arg His Pro Asp Gly Ser Leu Leu Lys Thr Thr 1045 1050 1055 Tyr Arg Tyr Asn Ala Ala Gly Glu Leu Thr Glu Val Ile Leu Pro Gly 1060 1065 1070 Asp Glu Thr Leu Thr Phe Ser Arg Asp Glu Ala Gly Arg Glu Val Leu 1075 1080 1085 Arg His Ser Asn Arg Gly Phe Ala Cys Glu Gln Gly Trp Asn Ala Ala 1090 1095 1100 Gly Gln Pro Val Ser Gln Arg Ala Gly Leu Phe Pro Ala Glu Ala Thr 1105 1110 1115 1120 Trp Gly Gly Leu Leu Pro Ser Leu Leu Arg Glu Tyr Arg Tyr Asp Ser 1125 1130 1135 Ala Gly Asn Val Ser Gly Val Thr Ser Arg Glu Asp Tyr Gly Arg Glu 1140 1145 1150 Thr His Arg Glu Tyr Arg Leu Asp Arg Asn Gly Gln Val Thr Ala Val 1155 1160 1165 Thr Ala Ser Gly Thr Gly Leu Gly Tyr Gly Glu Gly Asp Glu Thr Tyr 1170 1175 1180 Gly Tyr Asp Ser Cys Gly Tyr Leu Lys Ala Gln Ser Ala Gly Arg His 1185 1190 1195 1200 Arg Ile Ser Gly Glu Thr Asp Gln Tyr Ala Ala Gly His Arg Leu Lys 1205 1210 1215 Gln Ala Gly Asn Thr Gln Tyr Asp Tyr Asp Ala Ala Gly Arg Met Val 1220 1225 1230 Ser Arg Thr Lys His Arg Asp Gly Tyr Arg Pro Glu Thr Glu Arg Phe 1235 1240 1245 Arg Trp Asp Ser Arg Asp Gln Leu Thr Gly Tyr Arg Ser Ala Gln Gly 1250 1255 1260 Glu Gln Trp Glu Tyr Arg His Asp Ala Ser Gly Arg Arg Thr Glu Lys 1265 1270 1275 1280 Arg Cys Asp Arg Lys Lys Ile Arg Phe Thr Tyr Leu Trp Asp Gly Asp 1285 1290 1295 Ser Ile Ala Glu Ile Arg Glu Tyr Arg Asp Asp Lys Leu Tyr Ser Val 1300 1305 1310 Arg His Leu Val Phe Asn Gly Phe Glu Leu Ile Ser Gln Gln Phe Ser 1315 1320 1325 Arg Val Arg Gln Pro His Pro Ser Val Ala Pro Gln Trp Val Thr Arg 1330 1335 1340 Thr Asn His Ala Val Ser Asp Leu Thr Gly Arg Pro Leu Met Leu Phe 1345 1350 1355 1360 Asn Ser Glu Gly Lys Thr Val Trp Arg Pro Gly Gln Thr Ser Leu Trp 1365 1370 1375 Gly Leu Ala Leu Ser Leu Pro Ala Asp Thr Asp Tyr Pro Asp Pro Arg 1380 1385 1390 Gly Glu Arg Asp Pro Glu Ala Asp Pro Gly Leu Leu Tyr Ala Gly Gln 1395 1400 1405 Trp Gln Asp Ala Glu Ser Gly Leu Cys Tyr Asn Arg Phe Arg Tyr Tyr 1410 1415 1420 Glu Pro Glu Thr Gly Met Tyr Leu Val Ser Asp Pro Leu Gly Leu Gln 1425 1430 1435 1440 Gly Gly Glu Gln Thr Tyr Arg Tyr Val Pro Asn Pro Cys Gly Tyr Ile 1445 1450 1455 Asp Pro Leu Gly Leu Ala Ile Cys Gln Leu Ala Arg Trp Thr Lys Trp 1460 1465 1470 Gly Ser Glu Gln Ser Asn Ile Ser Asp Val Leu Asn Ser Leu Gly Asn 1475 1480 1485 Arg Ala Leu Lys Tyr Ala Asn Gly Asp Trp Ile Lys Ser Glu Ala Ala 1490 1495 1500 Phe Asn Lys Tyr Ile Asn Met Ile Asn Lys Arg Leu Glu Leu Thr Gly 1505 1510 1515 1520 Ser Lys Phe Arg Val Glu Ile Gln Pro Ala Ile Lys Asn Gly Glu Arg 1525 1530 1535 Val Pro Ala Thr Thr Asn Gly Pro Phe Lys Val Asn Gly Lys Trp Thr 1540 1545 1550 Ser Gly Thr His Tyr Thr Gly Gly Ser Lys Arg Leu Asp Ala Gly Ile 1555 1560 1565 Ile Asp Ile Thr Ser Pro Thr Asn Gln Tyr Gly Leu His Pro Val Ile 1570 1575 1580 Glu Gly Phe Asp Ile Thr Leu Asn Lys Thr Lys Pro Ser Ala Val Asp 1585 1590 1595 1600 Ile Tyr Ser Asp Val Phe Gly Gly Ile Asp Ile Asn Asp Phe Arg Leu 1605 1610 1615 * <210> 1307 <211> 154 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8510..8971) <400> 1307 Met Gln Phe Thr Phe Asn Glu Gly His Ile Gln Leu Pro Ser Gln Trp 1 5 10 15 Gln Asp Gln Ser Met Gln Val Leu Val Ser Thr Asp Asn Ser Gly Ile 20 25 30 Asn Leu Val Ile Thr Arg Glu Pro Val Ser Gln Gly Thr Leu Thr Pro 35 40 45 Glu Leu Tyr Gln Glu Thr Leu Ala Leu Tyr Gln Gly Lys Leu Asp Gly 50 55 60 Tyr Thr Glu His Ala Cys Arg Glu Ile Thr Leu Ala Glu Ala Pro Ala 65 70 75 80 Trp Leu Leu Asp Tyr Ser Trp Asn Gly Pro Glu Asp Glu Gly Asn Gln 85 90 95 Gly Arg Ile Ser Gln Ile Ala Val Phe Gln Arg Arg Gly Asp Thr Leu 100 105 110 Leu Thr Phe Thr Phe Ser Thr Ser Leu Ser Leu Lys Asn Ser Gln Lys 115 120 125 Thr Met Leu Leu Glu Val Ile Lys Ser Phe Thr Pro Leu Pro Pro Glu 130 135 140 Asn Asp Ile Gln Lys Asp Gln Pro Arg * 145 150 <210> 1308 <211> 634 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8999..10900) <400> 1308 Met Ser Thr Gly Leu Arg Phe Thr Leu Glu Val Asp Gly Leu Pro Pro 1 5 10 15 Asp Ala Phe Ala Val Val Ser Phe His Leu Thr Gln Ser Leu Ser Ser 20 25 30 Leu Phe Ser Leu Asp Leu Ser Leu Val Ser Gln Gln Phe Leu Ser Leu 35 40 45 Glu Phe Ala Gln Val Leu Asp Lys Met Ala Tyr Leu Thr Ile Trp Gln 50 55 60 Gly Asp Asp Val Gln Arg Arg Val Lys Gly Val Val Thr Trp Phe Glu 65 70 75 80 Leu Gly Glu Asn Asp Lys Asn Gln Met Leu Tyr Ser Met Lys Val His 85 90 95 Pro Pro Leu Trp Arg Ala Gly Leu Arg Gln Asn Phe Arg Ile Phe Gln 100 105 110 Asn Glu Asp Ile Lys Ser Ile Leu Gly Thr Ile Leu Gln Glu Asn Gly 115 120 125 Val Thr Glu Trp Ser Pro Leu Phe Ser Glu Pro His Pro Ser Arg Glu 130 135 140 Phe Cys Val Gln Tyr Gly Glu Thr Asp Tyr Asp Phe Leu Cys Arg Met 145 150 155 160 Ala Ala Glu Glu Gly Ile Phe Phe Tyr Glu Glu His Ala Tyr Lys Ser 165 170 175 Thr Asp Gln Ser Leu Val Leu Cys Asp Thr Val Arg His Leu Pro Glu 180 185 190 Ser Phe Glu Ile Pro Trp Asn Pro Asn Thr Arg Thr Glu Val Ser Thr 195 200 205 Leu Cys Ile Ser Gln Phe Arg Tyr Ser Ala Gln Ile Arg Pro Ser Ser 210 215 220 Val Val Thr Lys Asp Tyr Thr Phe Lys Arg Pro Gly Trp Ala Gly Arg 225 230 235 240 Phe Asp Gln Glu Gly Gln His Gln Asp Tyr Gln Arg Thr Gln Tyr Glu 245 250 255 Val Tyr Asp Tyr Pro Gly Arg Phe Lys Gly Ala His Gly Gln Asn Phe 260 265 270 Ala Arg Trp Gln Met Glu Gly Trp Arg Asn Asn Ala Glu Thr Ala Arg 275 280 285 Gly Met Ser Arg Ser Pro Glu Ile Trp Pro Gly Arg Arg Ile Val Leu 290 295 300 Thr Gly His Pro Gln Ala Asn Leu Asn Arg Glu Trp Gln Val Val Ala 305 310 315 320 Ser Glu Leu His Gly Glu Gln Pro Gln Ala Val Pro Gly Arg Arg Gly 325 330 335 Ala Gly Thr Ala Leu Glu Asn His Phe Ala Val Ile Pro Ala Asp Arg 340 345 350 Thr Trp Arg Pro Gln Pro Arg Leu Lys Pro Leu Val Asp Gly Pro Gln 355 360 365 Ser Ala Val Val Thr Gly Pro Glu Gly Glu Glu Ile Phe Cys Asp Glu 370 375 380 His Gly Arg Val Arg Val Lys Phe Asn Trp Asp Arg Tyr Asn Pro Ala 385 390 395 400 Asp Gln Asp Ser Ser Cys Trp Ile Arg Val Ala Gln Ala Trp Ala Gly 405 410 415 Thr Gly Phe Gly Asn Leu Ala Ile Pro Arg Val Gly Gln Glu Val Ile 420 425 430 Val Asp Phe Leu Asn Gly Asp Pro Asp Gln Pro Ile Ile Met Gly Arg 435 440 445 Thr Tyr His Gln Glu Asn Arg Thr Pro Gly Ser Leu Pro Gly Thr Lys 450 455 460 Thr Gln Met Thr Ile Arg Ser Lys Thr Tyr Met Gly Ser Gly Phe Asn 465 470 475 480 Glu Leu Lys Phe Asp Asp Ala Thr Gly Arg Glu Gln Val Tyr Ile His 485 490 495 Ala Gln Lys Asn Met Asp Thr Glu Val Leu Asn Asp Arg Thr Thr Thr 500 505 510 Val Lys His Asp His Arg Glu Thr Val Lys Asn Asp Gln Thr Val Thr 515 520 525 Ile Gln Glu Gly Asn Arg Leu Leu Thr Val Glu Lys Gly His Lys Ile 530 535 540 Thr Gly Val Leu Lys Gly Ser Leu Ser Glu Asp Val Phe Gln Asp Arg 545 550 555 560 Gly Thr Ile Ala Gly Ser Val His Val Asp Ala Val Asn Asn Gly Gly 565 570 575 Glu Gly Asn Gly Ile Gln Ala Tyr Thr Ala Ile Lys Glu Ile Met Leu 580 585 590 Ala Val Glu Glu Ser Lys Ile Ala Leu Thr Pro Asp Gly Ile Gln Leu 595 600 605 Gln Val Gly Glu Ser Thr Val Ile Arg Leu Ser Lys Asp Gly Ile Thr 610 615 620 Ile Val Gly Gly Ser Val Phe Ile Asn * 625 630 <210> 1309 <211> 10235 <212> DNA <213> Escherichia coli O157:H7 <400> 1309 gactcatcta aactattgtt ttaaaacaat ttaattcata atcttgcttg aaatcgcgta 60 gcccctctta caaaagggta tacgaggcga tgtctcagcg atataaactc tatcgtcgaa 120 ccagcggcat ttatgttgtc cgcattagcg ttccccaacg ttttcgtcga tacgcaggac 180 agtgtgagat tcacacttca acaggcactc acgatcttca tgaagcaaag cagaagtccg 240 cgctcctgtt ggcggtctgg tatcagacct tacaagagta tgaacaattg gattatcgaa 300 ctttaagtga ctgcgcccca ctgcttgctg gtgagggtat gatctcgctt tctaactttg 360 ctcaatcaat cgagttgcct atatcgcaat tgattcgaga ggtggttaat cgtaacctcc 420 cggtattctg gctggcgact ggtcagttcg gtttctatgt tgatgaattt aatgcagtag 480 agcgggaacc gggtgcaaaa cgagaaaaac agtctgatga tgaaaaggat caacctaaag 540 aagtcatcat tctcaatagc gcgtttgagc tgggtatcga gagcttcgca aatggttatc 600 tccgcccctt caatccccgg catactttag attgtctgtt gagcgctgga gtatccgaag 660 gagaggctgc atttcgaact agtggtgata accaaagtgg aggttggttc ttcgatttac 720 ccggcgtaga tataactgct gatagcctgt tgattagcaa agttcatgct gaaggccttc 780 gacttacatg gctggttaag accacgccac cagcagttag cattcaccct gccgtgcctc 840 ttgtcgctcc tgttatcgct aatgaatatg ttcaccgcaa acattacaat gaaaacttgt 900 catggcttcg tgaagagtat ttgaaacatc gacgtaaggg caaggtatca gaagcggcgc 960 tccgcgatat tcgctattac ttcgatttga tgattgaagt gatgggggat attcagttgg 1020 aagatttcga ccgtgatttc ctccgggctt atgagagcaa gttgcgcaca attcctgcta 1080 accgtaattt gatgaaaggt aagcacgggg ttaagacgct ggatgagtta atcgccaaag 1140 cggcagaatg tggcgataaa ctgatgacag aagagtctgt caaaaagtat atcaacggcc 1200 tttatggtgc aatggagtgg gctgttgatg atggtaagtt tctgaaatcg ccatgcgaca 1260 actttttccc tcccgatgac aaaggtgagc gagagcagga tcacactgac atatttgaac 1320 cgcatgaaat taaggcaatt ttttcgcaac cgtggtttgt cgctggaact gttgaacgta 1380 atgcgcaagg gcgattccat caatattgcc cgtttcacta ttgggcgccg ttgttgggct 1440 tgatgacggg ggcaagggtt aacgagattg cacagttaat gctggacgat gttctggcag 1500 atgacggcgt ttattacctg aaccttgaaa gcgatagcga aaacggaaag aaactaaaaa 1560 acgccaattc ccgccgcaag attccggttc attctacgct gattgaactc ggttttatcg 1620 agtatgtgga tgcgttgaaa gctgccgggt atgaccgtct ttttcccgag cttaaaccac 1680 ataaaaccaa aggctatggt aggccggttt ccgcatggtt caatgaatca ttgcttgcgg 1740 gtcgattaaa acttgaaaga gacagaagca aatctttcca ctctttccgg cattctgttt 1800 caactttgct taaagagaag ggtgttagtt cggaactgcg tgggcagcta cttgggcatg 1860 tgcgaggcaa aacagaaact gaagtgcgat acagcaaaga tttaaaaccg gttcacatgg 1920 ttgaggttgt cgaaaagatt gatttttctt tgcccgagat agcgagattc aacattcctg 1980 atgggctgga tgctgtaaga gatgcgctgc gaagaaagcg tggcaaacaa acaggttgag 2040 tcagttacta ttcagttgag ttatgctctt gaatgcgctg ggacgcttcc tggcgcattt 2100 tttattaaag gtcgtggatt taatagtgcc aaatttggag acgcttaaaa tgcgtctggt 2160 gagacttgat ttgcattagc tcagtgaacc gccccggaaa tcctggagac taaactccct 2220 gagaaagagg taaacaggat gactaaaaat actcgttttt cccccgaagt ccgtcagcgg 2280 gcgattcgta tggttctgga aagtcaggat gaatatgact cacagtgggc ggcaatttgt 2340 tccattgccc caaagattgg ctgtacgccg gagactctgc gtgtctgggt tcgccagcat 2400 gagcgggata ccgggggcgg tgatggtggg ctcaccagcg ctgaacgtca gcgtctgaaa 2460 gagctggaac gtgaaaatcg tgaactgcgc cgcagtaacg atatccttcg ccaggcttcc 2520 gcttattttg cgaaggcgga gttcgaccgc ctctggaaaa aatgatgcca ctgctggata 2580 agctgcgtga gcagtacggg gtcggaccgg tatgcagcga actgcatatt gccccgtcaa 2640 cgtattacca ttgtcagcaa cagcgacatc atccggataa acgcagtgcc cgtgcgcagc 2700 acgacgactg gctgaagaga gagatacagc gcgtatacga tgaaaatcat caggtgtacg 2760 gtgtgcgtaa agtctggcgt cagttgttac gggaaggaat cagggtggcc agatgtacag 2820 tggcacgtct catggcggtt atgggacttg ccggtgttct ccggggtaaa aaggtccgta 2880 cgaccatcag ccggaaagcc gttgccgcag gcgaccgcgt aaaccgtcag ttcgtggcag 2940 aacgacctga ccagctgtgg gtggctgatt ttacttacgt cagcacatgg cagggcttcg 3000 tctatgtggc gtttatcatt gatgtgtttg ccggatacat cgtggggtgg cgggtctcat 3060 cgtctatgga aacgacattc gtgctggatg cgctggagca ggcgttgtgg gcccgtcgtc 3120 cgtctggcac catccatcac agcgataaag gctctcagta tgtgtcactg gcctatacgg 3180 agcgactaaa agaagccgga ttactggcat caacagggag tacaggcgac tcgtatgaca 3240 acgcgatggc tgagagcatc aatggtcttt acaaagcgga ggtaatacac cgtaagagct 3300 ggaaaaaccg tgcagaagtg gaactggcca cactaacgtg ggtggactgg tataacaatc 3360 gacgattgct gggaaggctg ggccatactc ctccggcaga agcagaaaaa gcttattatg 3420 cttccatcgg aaacgatgat ctggcagcct gagttcacag ataaaacact ctccaggaaa 3480 cccggggcgg ttcacagaat tgatctgacg gttttctctg acagcataca atcaagtcta 3540 acagtccgcc ttgagcgagg agcggacact catgattctt acttatatat attttcctac 3600 atcgaatttt tttaggggaa aattatttag ttagtcacac tccgccagtc aattctgcga 3660 ttagtggttc ataaggtgcg ccagcttgta gtgcattcca gatttctaaa attttatcac 3720 gatttctccc caaccaactc gaaacatcac tatcatattt cttaggtaaa tctccctcta 3780 tgcggtctcc tgattgtatg gcataactgg cagcatgcgc ttgttttcca tagtcaatat 3840 gaatatgggg aagttgatgt cctttttctt gatatatttt tatcttcatg ttctgtctct 3900 tcaccaagag aatttccatg aatccgccgc cactagagcg tcttttctca gtcagtagat 3960 ccttctgagc aaagagtttt tgtaattcgt aaaattcttc atctaaattc atatatcacc 4020 cattaaattt cagttagtag ttattaaact caactcttta tcgctaggct tttcctagtc 4080 cacttttggc acaaagctgt ttaggtcaaa tctaagctaa tacacttgat tacttacgat 4140 tgcatccgca gccctttcac gctttctgat ggtaggctaa tcactgtttt aatgcagttc 4200 tctatgctgc caatgatgtc ttcgcgtggg ccgctgcgcc agtctgcgct tgcgtaaaaa 4260 gcatcgagaa ccgcagtcat gcttttagcg ctgtcaaagg cgcgaatcaa gtagtagcaa 4320 tccaggtcat caagcgagtt gccaaacgaa acaacatcga tcccgtggct ttggtgtagg 4380 ggaacactga tttcctgcat tatggcgtga aaagcggcac cgctgccttt gcgtaaggtg 4440 tattgcagta tttcgacggt tctcaagcgt tatctccgtg ttgcccttgg gcggctccta 4500 gttgatagca ataaagtaaa ccggactggg ccatgaagct actgctaatc agacagtcat 4560 ccgtaagcag aagctgcgat atgcggttca aacgcgctgt aaggctctct ggcgagtgtt 4620 ttaaagaagg tagtcgaaat catggtgcag aattcgcggc gctctcatag agtgactggt 4680 gaagccagtt gaaacaagcg tagcggagtt cgagcaatca atgagaaatc tgggcgagct 4740 ttagttttac cgcgtcgctt aactttggag gctgattgcc tctataagga ctgtctcacc 4800 gccacggaaa ttatcggatg caatgcttaa gaggggcgct tccaaaccta ggacatccac 4860 tttttcgctc ccaacttatc cggctgcatt tacaccgcga acacgttgaa cgttagcagc 4920 ttctggttcg tgtttggttg ttacgcatgt gaggtaaaaa cggcagcttt acttttgacg 4980 ggaacgccat aagacaccaa acagcagaga agtgtaattg ttaaaaatgt taaaacataa 5040 cttgttcttt aagatgtaaa cccttcctcg ggggggaagc cggacatatc aaccctaagg 5100 ccatctgaga agatagcctg taggtttgct cggttcccct tgccagatga agatcaagtc 5160 ttcctcgtgg tgtgacgacc tttcttgaaa gatgcattat gcgcaaaaga agctacttaa 5220 gaatccgccg atagctactt tcaccctctg cttggctgca tcaaacgctt gcgcgcccta 5280 cctaccacaa tcaacgttac gcagagttcc catcctgacg tcttccgcta aacagcggtg 5340 atctccacct acccggaccg gtttaccgca tgaggtaggt gtcaggagag aagctagcac 5400 accatcattt taaagaaaag tcatatatat catatggctg cgttcatatt ctgaacgcag 5460 ttatcgatgt taacctaaag gtatgagaac actgtcgttt ttcatataca aagggtgctt 5520 cggctcacct gtagcgttta agacgaagca cattgtgctc tctggcaata gctgtcggac 5580 ggtcgttgag cgtttgaggt gtcttccttc atttccccat gcggcgacaa ccagtccggc 5640 accgctaaca agacgtatca agtggctatc gttatctttg ccaatgggat cagacgcttt 5700 catcatttca tgtcgctggg tgtgaacgaa tgcgaacagg ttggccatgt atacgccacc 5760 gtagccccag cttttggcaa acgatatgca gcggctcaag gtgcgatcat ccttctcggc 5820 atcggcgtat gaagggttta gccctatgaa aagggtatac ggttttgatt cgtcccagac 5880 tcgtgataac gagtagcgat acttaccgca cggtgaaaaa atcgcgtctt taatcatttc 5940 ggttgtcctt atgaagtgat ggtttcagcc taacatgtct tcacccgttt taagcgccaa 6000 caaacgaccg ttttccggca tcctccaacc gcacgctttc acactgttgg aaaattagcc 6060 ttggcttttc cggcaggcca tcctattttc atcaccgttt tctggcaggg gccggatgag 6120 gagatgacta tggctatttt tggctacggg cgtgtttcga catcccagca ggatactgag 6180 aaccagcgca tggaacttga acaagctggg tggacgttcg acttttggtt ttctgatgta 6240 gtcagcggaa aggttcctgc ggtgcaacgc aaagcgtttt ttgaaatgct cagcaaaatc 6300 cgcgatgggg aaacgttggt agttgcaaag ctggaccgcc tcgggcgtga tgcaattgac 6360 gttctgcaaa ctgtcaggac gttggctgac cgaaacatca aggttattgt ccatcagctt 6420 ggcaccactg atctcacctc tgctgccggt aagctcctgt tgtcgatgct agcagcggtt 6480 gcggagatgg agcgtgacct gctgattgaa cggactaatg cggggctgtt acgggcaaaa 6540 gctgaaggca ggaaattggg caggcctgct aaaatcgcac cggaagctcg tggagcgatt 6600 ttagacaaaa gggccgctgg ggttagtgtt agcgcattgg cgcgtgaata cggtgtttca 6660 agagcgacgc ttgctgcatt actgaataag ggttactgat atacttaaaa catgctctaa 6720 cactttgcag atacgagcaa tacttggtaa aacagcacac tttccgccag aatcggattt 6780 ttgaggtcct ggcaacagct aattgctgag aacatttcag taaactgttt aactcgctat 6840 cagccgaaca ctgatttgta tagaaatgct accctcgttc atactatcaa aaataaatta 6900 attttgatgc cagccaggtt ggtcattctc aaatacctca gcctcgggga atattttagt 6960 caatgggata acatatttga ccagatcatg ggtaaaaaag tcatccgcag tttcatctac 7020 catccacgca gagttctcat ctatgcgtgg cacgagataa tgaacattca ggcggactat 7080 tttagatttt tgctcaaaat ttactatggc agcatagttt ttttcccttc gtttatcggc 7140 aacatccttt tgaatatcta catccaaagc tatatgccct acgcctagac cataatccaa 7200 aagctggtta tctatctctg ctaatgtttt tgttacatgt cgcgaacgtg catcgaaaga 7260 tttttcattg atacaacgcc atgttatcaa agaagcaagt ttaactttgg ttatgaaacg 7320 tgagtcgcgc tcatctggtc gtcccatagc aacaacttgg taattttcat cttccagagg 7380 ggagcctttg ataagacgag caagtttagt gttgactagt aatgagccgt tttcagtgat 7440 atcttccctg ataagattta agttggccgg tctaatcgtt ccttttccat aatcatcatt 7500 ccattcataa aatacacctt taaagttttt taagtggcta atgatatagt tttcaggcgc 7560 gtctttaact tcacataaat atgtgacatc agtccatacg ttcatctttt tggatttgat 7620 atgaagttcg gcaagatgtg agcgtatatg atgctgtaat atttcctgct ttacgtaagg 7680 acctttctga agccttttgc attcgacaaa gaaataatcg ccatctccaa ggcggcaacg 7740 aaactccggg gtttttgcta tccctttttg ttctggaatg aactcaactt cataaccttc 7800 tgatgcatag tttccagcaa gaaccaactc taataaggct gtgtctggta atactgttgt 7860 attcttaagc attctgattg cgcgatctct agcgccagta attctatcga gcgatttagc 7920 acacactcct aattgtttaa cccatggtat tatatttgaa gcattagtaa cttcgtaaga 7980 ccttctatta tcgataagcg attttgcttg tgcgaaataa ccagcaacca cgtcggaacc 8040 ataccattct gggtcaaact gtttcccgaa attggcagct ttttgggttg tagctatgta 8100 aaattgctgt gcttttgcta agcgctggta aaagtgttgt ttgttctctt gagttgatgc 8160 taaccactca agaccagcaa taacgtcaga atctagcata acaccgtcat tcatctttat 8220 tccttagttc agccctgaaa ggcactagat caactgagac agattatagt tacggaaaga 8280 taacgcgatg aatatacgat ggtaagcctc cgctttccac tctatgctgg cagctgagtt 8340 ctatcatgtt caggcaccta cgtttctaga agttgttcat acagttagta taaatatacg 8400 tccctgaaat ctttgcgtct tgctttggat gttcatatac gtagtcaaca aaagtcttat 8460 agagcgttat catctgctgg gtgacgtcgg ccttaccgtt catgttatca agtcgctgat 8520 aatattctct tttcgtcatc ccactgttac ggccttcggt tacgtttgcg gtaaattgag 8580 ccatacccat gcacatttga tctttattgt tattcatttg atctttattg ttattcgttt 8640 tatccgggtg gagagcgcct tccaacactt tatcaccgct gatggcatgt tgcgcccacg 8700 ctgaattgtt agcgataaac tttttggagc cgatggcaat accgtattca acgcgaattc 8760 cattgtcgtg ataactgcca tctgcgtctt ttgtcgctag ctttaaagat atacggcaac 8820 cgggaagcgt tttgtgttct tgcaccgaga taataacggt gtccgtatcg caatcagcaa 8880 agctgtattc ggggttaacg taagtgttag ttttgattaa cagcccggta agaccgtttt 8940 tatagccttt tgccggcagc gttttgaagg cgctgcgttc accctttttg atcgcttccc 9000 ggaagtgatc cataccgatg cgcgtcgcca gttgatcgat gctttctgct gcataagatg 9060 cagatgacgc agcgattaac ataatggtca gcacagactt ggctgaaaaa ccgggcttac 9120 taagccgtgt ttttgacatg ttgttatccc tcagaatcca ccccagcggt gtcagttatc 9180 gcatcataga ccattgattc aaaatgtcac tattggagcg tggctcttta gtggacatct 9240 gcgcaaattc aggtcatgaa aatgaccctg agaaaactgt ttggacaacg agtaaaagag 9300 ttgcgcattg ccaccggaat gagccaagaa gcctttgccg atcggtgtgg ttttgctcgt 9360 agctatatga gccgcattga acgcggtggc tctaatgcgt ctttggatgc gattgaggtg 9420 ctggctaatg ctctgagtgt tgagccgtgg cgactattgg tgtctgattc atctgaagat 9480 agtgacccgg aattactggt tccttatgca gctgatggct cgtgttttca tcccgggctg 9540 gcaagcactc gcgatggctc gtttggcgta ggtgataaaa cggctcagaa gcggtttggc 9600 acgttttctg aagctcttga gtatcttcgt agcatggaga cagcaaaatg gcgtaggcct 9660 aatcctagcg gcaactgggg tattgtatct gcggttcggt gggacaagct gagaaagtag 9720 ctcaagtgta agtttatgaa ttttcatgct gtatggatga acagtgttca ttagatgctg 9780 atagcctcac gtttcatcag ctctttgttt ctataagagt gaataaaaca gcaaaatgcg 9840 ggtgcgttac gtaggcgtta cggtggcgtt ttactttgac gctgaatggc ttaattcata 9900 taaataacat tgagttaaat agttattctg aacaaggtct gacggggttt aactggtttc 9960 aaaatccgaa cgcagtggcg tttacttaac atccacatag ctgacaaatg ttctttcctc 1002 0 ccgacccact agacctccat aaacatcaaa aggcaggtat ggcacgttaa tgatttgtgc 1008 0 cgccacgaac actcggtttg attccgtcca gcggatcaaa cttaagatgt agcccctaga 1014 0 acaaaaaggt cctacgattg ttcttttaaa ggctaatagg aacgtgatta cagcaggtta 1020 0 tggagactta ggttcgagtc cggccttcgg cacca 1023 5 <210> 1310 <211> 650 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(90..2039) <400> 1310 Met Ser Gln Arg Tyr Lys Leu Tyr Arg Arg Thr Ser Gly Ile Tyr Val 1 5 10 15 Val Arg Ile Ser Val Pro Gln Arg Phe Arg Arg Tyr Ala Gly Gln Cys 20 25 30 Glu Ile His Thr Ser Thr Gly Thr His Asp Leu His Glu Ala Lys Gln 35 40 45 Lys Ser Ala Leu Leu Leu Ala Val Trp Tyr Gln Thr Leu Gln Glu Tyr 50 55 60 Glu Gln Leu Asp Tyr Arg Thr Leu Ser Asp Cys Ala Pro Leu Leu Ala 65 70 75 80 Gly Glu Gly Met Ile Ser Leu Ser Asn Phe Ala Gln Ser Ile Glu Leu 85 90 95 Pro Ile Ser Gln Leu Ile Arg Glu Val Val Asn Arg Asn Leu Pro Val 100 105 110 Phe Trp Leu Ala Thr Gly Gln Phe Gly Phe Tyr Val Asp Glu Phe Asn 115 120 125 Ala Val Glu Arg Glu Pro Gly Ala Lys Arg Glu Lys Gln Ser Asp Asp 130 135 140 Glu Lys Asp Gln Pro Lys Glu Val Ile Ile Leu Asn Ser Ala Phe Glu 145 150 155 160 Leu Gly Ile Glu Ser Phe Ala Asn Gly Tyr Leu Arg Pro Phe Asn Pro 165 170 175 Arg His Thr Leu Asp Cys Leu Leu Ser Ala Gly Val Ser Glu Gly Glu 180 185 190 Ala Ala Phe Arg Thr Ser Gly Asp Asn Gln Ser Gly Gly Trp Phe Phe 195 200 205 Asp Leu Pro Gly Val Asp Ile Thr Ala Asp Ser Leu Leu Ile Ser Lys 210 215 220 Val His Ala Glu Gly Leu Arg Leu Thr Trp Leu Val Lys Thr Thr Pro 225 230 235 240 Pro Ala Val Ser Ile His Pro Ala Val Pro Leu Val Ala Pro Val Ile 245 250 255 Ala Asn Glu Tyr Val His Arg Lys His Tyr Asn Glu Asn Leu Ser Trp 260 265 270 Leu Arg Glu Glu Tyr Leu Lys His Arg Arg Lys Gly Lys Val Ser Glu 275 280 285 Ala Ala Leu Arg Asp Ile Arg Tyr Tyr Phe Asp Leu Met Ile Glu Val 290 295 300 Met Gly Asp Ile Gln Leu Glu Asp Phe Asp Arg Asp Phe Leu Arg Ala 305 310 315 320 Tyr Glu Ser Lys Leu Arg Thr Ile Pro Ala Asn Arg Asn Leu Met Lys 325 330 335 Gly Lys His Gly Val Lys Thr Leu Asp Glu Leu Ile Ala Lys Ala Ala 340 345 350 Glu Cys Gly Asp Lys Leu Met Thr Glu Glu Ser Val Lys Lys Tyr Ile 355 360 365 Asn Gly Leu Tyr Gly Ala Met Glu Trp Ala Val Asp Asp Gly Lys Phe 370 375 380 Leu Lys Ser Pro Cys Asp Asn Phe Phe Pro Pro Asp Asp Lys Gly Glu 385 390 395 400 Arg Glu Gln Asp His Thr Asp Ile Phe Glu Pro His Glu Ile Lys Ala 405 410 415 Ile Phe Ser Gln Pro Trp Phe Val Ala Gly Thr Val Glu Arg Asn Ala 420 425 430 Gln Gly Arg Phe His Gln Tyr Cys Pro Phe His Tyr Trp Ala Pro Leu 435 440 445 Leu Gly Leu Met Thr Gly Ala Arg Val Asn Glu Ile Ala Gln Leu Met 450 455 460 Leu Asp Asp Val Leu Ala Asp Asp Gly Val Tyr Tyr Leu Asn Leu Glu 465 470 475 480 Ser Asp Ser Glu Asn Gly Lys Lys Leu Lys Asn Ala Asn Ser Arg Arg 485 490 495 Lys Ile Pro Val His Ser Thr Leu Ile Glu Leu Gly Phe Ile Glu Tyr 500 505 510 Val Asp Ala Leu Lys Ala Ala Gly Tyr Asp Arg Leu Phe Pro Glu Leu 515 520 525 Lys Pro His Lys Thr Lys Gly Tyr Gly Arg Pro Val Ser Ala Trp Phe 530 535 540 Asn Glu Ser Leu Leu Ala Gly Arg Leu Lys Leu Glu Arg Asp Arg Ser 545 550 555 560 Lys Ser Phe His Ser Phe Arg His Ser Val Ser Thr Leu Leu Lys Glu 565 570 575 Lys Gly Val Ser Ser Glu Leu Arg Gly Gln Leu Leu Gly His Val Arg 580 585 590 Gly Lys Thr Glu Thr Glu Val Arg Tyr Ser Lys Asp Leu Lys Pro Val 595 600 605 His Met Val Glu Val Val Glu Lys Ile Asp Phe Ser Leu Pro Glu Ile 610 615 620 Ala Arg Phe Asn Ile Pro Asp Gly Leu Asp Ala Val Arg Asp Ala Leu 625 630 635 640 Arg Arg Lys Arg Gly Lys Gln Thr Gly * 645 <210> 1311 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2239..2565) <400> 1311 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1312 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2562..3452) <400> 1312 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 1313 <211> 95 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3635..3919) <400> 1313 Met Glu Ile Leu Leu Val Lys Arg Gln Asn Met Lys Ile Lys Ile Tyr 1 5 10 15 Gln Glu Lys Gly His Gln Leu Pro His Ile His Ile Asp Tyr Gly Lys 20 25 30 Gln Ala His Ala Ala Ser Tyr Ala Ile Gln Ser Gly Asp Arg Ile Glu 35 40 45 Gly Asp Leu Pro Lys Lys Tyr Asp Ser Asp Val Ser Ser Trp Leu Gly 50 55 60 Arg Asn Arg Asp Lys Ile Leu Glu Ile Trp Asn Ala Leu Gln Ala Gly 65 70 75 80 Ala Pro Tyr Glu Pro Leu Ile Ala Glu Leu Thr Gly Gly Val * 85 90 <210> 1314 <211> 111 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4134..4466) <400> 1314 Leu Arg Thr Val Glu Ile Leu Gln Tyr Thr Leu Arg Lys Gly Ser Gly 1 5 10 15 Ala Ala Phe His Ala Ile Met Gln Glu Ile Ser Val Pro Leu His Gln 20 25 30 Ser His Gly Ile Asp Val Val Ser Phe Gly Asn Ser Leu Asp Asp Leu 35 40 45 Asp Cys Tyr Tyr Leu Ile Arg Ala Phe Asp Ser Ala Lys Ser Met Thr 50 55 60 Ala Val Leu Asp Ala Phe Tyr Ala Ser Ala Asp Trp Arg Ser Gly Pro 65 70 75 80 Arg Glu Asp Ile Ile Gly Ser Ile Glu Asn Cys Ile Lys Thr Val Ile 85 90 95 Ser Leu Pro Ser Glu Ser Val Lys Gly Leu Arg Met Gln Ser * 100 105 110 <210> 1315 <211> 59 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5030..5206) <400> 1315 Leu Arg Ile Met His Leu Ser Arg Lys Val Val Thr Pro Arg Gly Arg 1 5 10 15 Leu Asp Leu His Leu Ala Arg Gly Thr Glu Gln Thr Tyr Arg Leu Ser 20 25 30 Ser Gln Met Ala Leu Gly Leu Ile Cys Pro Ala Ser Pro Pro Arg Lys 35 40 45 Gly Leu His Leu Lys Glu Gln Val Met Phe * 50 55 <210> 1316 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5470..5937) <400> 1316 Met Ile Lys Asp Ala Ile Phe Ser Pro Cys Gly Lys Tyr Arg Tyr Ser 1 5 10 15 Leu Ser Arg Val Trp Asp Glu Ser Lys Pro Tyr Thr Leu Phe Ile Gly 20 25 30 Leu Asn Pro Ser Tyr Ala Asp Ala Glu Lys Asp Asp Arg Thr Leu Ser 35 40 45 Arg Cys Ile Ser Phe Ala Lys Ser Trp Gly Tyr Gly Gly Val Tyr Met 50 55 60 Ala Asn Leu Phe Ala Phe Val His Thr Gln Arg His Glu Met Met Lys 65 70 75 80 Ala Ser Asp Pro Ile Gly Lys Asp Asn Asp Ser His Leu Ile Arg Leu 85 90 95 Val Ser Gly Ala Gly Leu Val Val Ala Ala Trp Gly Asn Glu Gly Arg 100 105 110 His Leu Lys Arg Ser Thr Thr Val Arg Gln Leu Leu Pro Glu Ser Thr 115 120 125 Met Cys Phe Val Leu Asn Ala Thr Gly Glu Pro Lys His Pro Leu Tyr 130 135 140 Met Lys Asn Asp Ser Val Leu Ile Pro Leu Gly * 145 150 155 <210> 1317 <211> 192 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6124..6699) <400> 1317 Met Thr Met Ala Ile Phe Gly Tyr Gly Arg Val Ser Thr Ser Gln Gln 1 5 10 15 Asp Thr Glu Asn Gln Arg Met Glu Leu Glu Gln Ala Gly Trp Thr Phe 20 25 30 Asp Phe Trp Phe Ser Asp Val Val Ser Gly Lys Val Pro Ala Val Gln 35 40 45 Arg Lys Ala Phe Phe Glu Met Leu Ser Lys Ile Arg Asp Gly Glu Thr 50 55 60 Leu Val Val Ala Lys Leu Asp Arg Leu Gly Arg Asp Ala Ile Asp Val 65 70 75 80 Leu Gln Thr Val Arg Thr Leu Ala Asp Arg Asn Ile Lys Val Ile Val 85 90 95 His Gln Leu Gly Thr Thr Asp Leu Thr Ser Ala Ala Gly Lys Leu Leu 100 105 110 Leu Ser Met Leu Ala Ala Val Ala Glu Met Glu Arg Asp Leu Leu Ile 115 120 125 Glu Arg Thr Asn Ala Gly Leu Leu Arg Ala Lys Ala Glu Gly Arg Lys 130 135 140 Leu Gly Arg Pro Ala Lys Ile Ala Pro Glu Ala Arg Gly Ala Ile Leu 145 150 155 160 Asp Lys Arg Ala Ala Gly Val Ser Val Ser Ala Leu Ala Arg Glu Tyr 165 170 175 Gly Val Ser Arg Ala Thr Leu Ala Ala Leu Leu Asn Lys Gly Tyr * 180 185 190 <210> 1318 <211> 439 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6898..8214) <400> 1318 Met Asn Asp Gly Val Met Leu Asp Ser Asp Val Ile Ala Gly Leu Glu 1 5 10 15 Trp Leu Ala Ser Thr Gln Glu Asn Lys Gln His Phe Tyr Gln Arg Leu 20 25 30 Ala Lys Ala Gln Gln Phe Tyr Ile Ala Thr Thr Gln Lys Ala Ala Asn 35 40 45 Phe Gly Lys Gln Phe Asp Pro Glu Trp Tyr Gly Ser Asp Val Val Ala 50 55 60 Gly Tyr Phe Ala Gln Ala Lys Ser Leu Ile Asp Asn Arg Arg Ser Tyr 65 70 75 80 Glu Val Thr Asn Ala Ser Asn Ile Ile Pro Trp Val Lys Gln Leu Gly 85 90 95 Val Cys Ala Lys Ser Leu Asp Arg Ile Thr Gly Ala Arg Asp Arg Ala 100 105 110 Ile Arg Met Leu Lys Asn Thr Thr Val Leu Pro Asp Thr Ala Leu Leu 115 120 125 Glu Leu Val Leu Ala Gly Asn Tyr Ala Ser Glu Gly Tyr Glu Val Glu 130 135 140 Phe Ile Pro Glu Gln Lys Gly Ile Ala Lys Thr Pro Glu Phe Arg Cys 145 150 155 160 Arg Leu Gly Asp Gly Asp Tyr Phe Phe Val Glu Cys Lys Arg Leu Gln 165 170 175 Lys Gly Pro Tyr Val Lys Gln Glu Ile Leu Gln His His Ile Arg Ser 180 185 190 His Leu Ala Glu Leu His Ile Lys Ser Lys Lys Met Asn Val Trp Thr 195 200 205 Asp Val Thr Tyr Leu Cys Glu Val Lys Asp Ala Pro Glu Asn Tyr Ile 210 215 220 Ile Ser His Leu Lys Asn Phe Lys Gly Val Phe Tyr Glu Trp Asn Asp 225 230 235 240 Asp Tyr Gly Lys Gly Thr Ile Arg Pro Ala Asn Leu Asn Leu Ile Arg 245 250 255 Glu Asp Ile Thr Glu Asn Gly Ser Leu Leu Val Asn Thr Lys Leu Ala 260 265 270 Arg Leu Ile Lys Gly Ser Pro Leu Glu Asp Glu Asn Tyr Gln Val Val 275 280 285 Ala Met Gly Arg Pro Asp Glu Arg Asp Ser Arg Phe Ile Thr Lys Val 290 295 300 Lys Leu Ala Ser Leu Ile Thr Trp Arg Cys Ile Asn Glu Lys Ser Phe 305 310 315 320 Asp Ala Arg Ser Arg His Val Thr Lys Thr Leu Ala Glu Ile Asp Asn 325 330 335 Gln Leu Leu Asp Tyr Gly Leu Gly Val Gly His Ile Ala Leu Asp Val 340 345 350 Asp Ile Gln Lys Asp Val Ala Asp Lys Arg Arg Glu Lys Asn Tyr Ala 355 360 365 Ala Ile Val Asn Phe Glu Gln Lys Ser Lys Ile Val Arg Leu Asn Val 370 375 380 His Tyr Leu Val Pro Arg Ile Asp Glu Asn Ser Ala Trp Met Val Asp 385 390 395 400 Glu Thr Ala Asp Asp Phe Phe Thr His Asp Leu Val Lys Tyr Val Ile 405 410 415 Pro Leu Thr Lys Ile Phe Pro Glu Ala Glu Val Phe Glu Asn Asp Gln 420 425 430 Pro Gly Trp His Gln Asn * 435 <210> 1319 <211> 258 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8366..9139) <400> 1319 Met Ser Lys Thr Arg Leu Ser Lys Pro Gly Phe Ser Ala Lys Ser Val 1 5 10 15 Leu Thr Ile Met Leu Ile Ala Ala Ser Ser Ala Ser Tyr Ala Ala Glu 20 25 30 Ser Ile Asp Gln Leu Ala Thr Arg Ile Gly Met Asp His Phe Arg Glu 35 40 45 Ala Ile Lys Lys Gly Glu Arg Ser Ala Phe Lys Thr Leu Pro Ala Lys 50 55 60 Gly Tyr Lys Asn Gly Leu Thr Gly Leu Leu Ile Lys Thr Asn Thr Tyr 65 70 75 80 Val Asn Pro Glu Tyr Ser Phe Ala Asp Cys Asp Thr Asp Thr Val Ile 85 90 95 Ile Ser Val Gln Glu His Lys Thr Leu Pro Gly Cys Arg Ile Ser Leu 100 105 110 Lys Leu Ala Thr Lys Asp Ala Asp Gly Ser Tyr His Asp Asn Gly Ile 115 120 125 Arg Val Glu Tyr Gly Ile Ala Ile Gly Ser Lys Lys Phe Ile Ala Asn 130 135 140 Asn Ser Ala Trp Ala Gln His Ala Ile Ser Gly Asp Lys Val Leu Glu 145 150 155 160 Gly Ala Leu His Pro Asp Lys Thr Asn Asn Asn Lys Asp Gln Met Asn 165 170 175 Asn Asn Lys Asp Gln Met Cys Met Gly Met Ala Gln Phe Thr Ala Asn 180 185 190 Val Thr Glu Gly Arg Asn Ser Gly Met Thr Lys Arg Glu Tyr Tyr Gln 195 200 205 Arg Leu Asp Asn Met Asn Gly Lys Ala Asp Val Thr Gln Gln Met Ile 210 215 220 Thr Leu Tyr Lys Thr Phe Val Asp Tyr Val Tyr Glu His Pro Lys Gln 225 230 235 240 Asp Ala Lys Ile Ser Gly Thr Tyr Ile Tyr Thr Asn Cys Met Asn Asn 245 250 255 Phe * <210> 1320 <211> 155 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9256..9720) <400> 1320 Met Lys Met Thr Leu Arg Lys Leu Phe Gly Gln Arg Val Lys Glu Leu 1 5 10 15 Arg Ile Ala Thr Gly Met Ser Gln Glu Ala Phe Ala Asp Arg Cys Gly 20 25 30 Phe Ala Arg Ser Tyr Met Ser Arg Ile Glu Arg Gly Gly Ser Asn Ala 35 40 45 Ser Leu Asp Ala Ile Glu Val Leu Ala Asn Ala Leu Ser Val Glu Pro 50 55 60 Trp Arg Leu Leu Val Ser Asp Ser Ser Glu Asp Ser Asp Pro Glu Leu 65 70 75 80 Leu Val Pro Tyr Ala Ala Asp Gly Ser Cys Phe His Pro Gly Leu Ala 85 90 95 Ser Thr Arg Asp Gly Ser Phe Gly Val Gly Asp Lys Thr Ala Gln Lys 100 105 110 Arg Phe Gly Thr Phe Ser Glu Ala Leu Glu Tyr Leu Arg Ser Met Glu 115 120 125 Thr Ala Lys Trp Arg Arg Pro Asn Pro Ser Gly Asn Trp Gly Ile Val 130 135 140 Ser Ala Val Arg Trp Asp Lys Leu Arg Lys * 145 150 <210> 1321 <211> 9214 <212> DNA <213> Escherichia coli O157:H7 <400> 1321 actttcagct ttcacttcga caagaagtac gcacaatgat taatcagatg aatgatgcgg 60 agtgtaacca tgaaacccgt cgtgctggtg gtggatgatg acacggctat ctgcgcactg 120 ttgcaggacg tgttaagtga acatgtcttt acggtttcag tctgccatac cggacaggag 180 gccatattgc gtattgaggg cgatcctgac attgcgctgg tggtgctgga tatgatgcta 240 cccgatacca acggcctgag ggtattgcag caaatccaga aactgcgtcc gacattgccg 300 gtggtgatgt tgaccggcat gggcagtgag tctgatgtgg tggtcgggct ggaaatgggc 360 gcggatgatt acatctgcaa accgttcacc ccgcgggtgg tggtcgcacg actgaaagcg 420 gtgttgcgac gggttggcgc gctggcggtt aatgacgaga aaagcgccgg gctgtcattc 480 aatggctggt atctcgatac catgcgctgc cagttgcaca atccgcttca gcaacatgtc 540 gagttaactc agggcgaata tggcttgtta ctggctctgg cgcaaaacgc gcgtcgggta 600 ttgagccgcg agcagttgct ggcgttcacc cacagcgaca gcgtggaggt gtttgatcgc 660 accatcgacg tattaatcat gcgcttacga cgcaaaatcg aactcaaccc gcatcagccg 720 atgttgatta aaactctgcg cggtctgggg tatgtcttcg ctgccgacgt gcattaatcc 780 gacatttctg tttgcagctc ttccagcgtt ttcgccccgt cgatggcatt ggcgcataac 840 aggcttgccc gcgcgcaggc gtgtgccagt ttgatgctct cggtaagcgt ccagcgttca 900 tggcagccat ataaaaatcc ggcacaaaat gcatcgcccg cgccgacgct gccgataatt 960 tcccgttgtt ctaacttttg cgaagggatc cacacgccgc cctgttctgg ggtctctccc 1020 cacgcccctt ccgggtagtg gatcaccacc cgctggcgca cgcccgcatc taacagttca 1080 cgcgcggcgg cagcaatatg cgcgatatgc ggttcgccgt tgggtaaccg aatttccagc 1140 ccgctaaact ccccggcctc cagttcgtta attaccagat aatccagatg gcgcaacgcg 1200 ggcagcacca gcggctgata acgcggatcg cccttacggg agaccaggtc gagtgaggtt 1260 tcaaagccag tatcacgcat ttgcgccagc aggcgtgcgc tacgggtgcc gtaaacatcg 1320 tccggcatat ccaggctgtc gagcaacagt aaatagccga gatggaaaat cttcatggtg 1380 ttatcgagct gatcgaacgc cggaagatcc aaaagtctgt ttgcacccgg cgaatggaaa 1440 aacgtccgct gcccgcttgg gtctgtcatc acctgcgaca tcgacgtcgg ggcaaaggta 1500 gtgcgctgca catgctgacg attgacgtga tattgctcaa gcatcgccat gatgtaatcg 1560 ccgtcgctgt cctgaccgat tagcccaacc gcctgtaacg gcagcccggt gcgcattttc 1620 gccagcgtca gcaggacgtt aagcggcgca ccgccggtgg agcgttcgct gtgggtgatc 1680 tccgccagcc agccgcgctc tggccactgg ataatctgat ggacgtggtc aaccaacata 1740 ttgcctgcgg cgataatccc tttacgctcc atcatgcctg ccccgcactg ccaaaaatac 1800 gcatctgttg tgcaaccgta tcgctgatgg cggcttccac tgccagcagt aactcggcaa 1860 actcgtcata catcggctga cggtgcgcca ttcgggcctc aacggcagcc agcgccgctt 1920 gcgacatgcc agtgtagaaa ttgattttgt ggatacccag ttcgatggcg cggcggaaat 1980 cggcatcgct aatccctgag ccgccgtgta ataccagcgg gatagcagcc tgctggcgga 2040 tagcgtcgag gcgcgggaaa tcgagtttcg gttcgccgcg atatttgccg tgtgcattgc 2100 caatcgccac ggccagcgcg tcaatgccgg tacggtcgac aaaatcacgc gccagttgcg 2160 gatcggtaaa cagggattca tcggcatgac catagagtgc accgccttcg tcgccaccca 2220 ccgcgcccag ttcagcttct accgatacgc caacggcatg gcacattttc accacttccc 2280 gcgtctggcg gacattttct tcatacccca gcgtggagcc atcaaacatt accgagctga 2340 atcccagccg caacgcttgc accaccgatt caaaatgtag tccgtgatcg agatttaaca 2400 ccaccggaat gtcatgacgc gccgcttcaa atttcactgt ctcgaccagg gaatccagcg 2460 agatatattt aaaatgtact tcggcaatgt tgataataaa gggcgaacgt tcttgtctgg 2520 cagcagcaaa caaggcgcgt aaaaagtgcg agtccagcac attaaacgca cctaacgaat 2580 agtgatgttc gcgggcatgt gccagccctt cagcgagaga aatcaatggc ataacgttat 2640 ccttattcag cggaactggc ggtattcgtt acacaatacc aactgtgcag gttcgtcttc 2700 gtcaatcagg ttgtagcggt ccagtggctg taaaaagtgg ttatcgtggt cgtcgtcatt 2760 aacagaagag acttcgccaa ccagcacatc gccaaaaccg gcttctgccc aaaagctgtg 2820 atacaggccg ggcggcaggc agatactttc gccgggagac aggcgcaact gagagcctgc 2880 agtatgtttc tggcggcagc cgtctatcac caccgtaatg tcactatcag ccgtttgctc 2940 gttactatcg gcattccaca gttcaacaat taaattaccg ccgccgcgat tgataatgtc 3000 ctcacgctta cgccagtgaa aatgcattgg cgtgacctgc gcatcgcgca catgcatgat 3060 cttctcggcg taacatttca catacggcat tccttttgct gagccgttac gtagggtaaa 3120 cagcgtcagc ccgtgtgctg caaagttgtt gcgaccaaaa gcggtaacat cccagccgag 3180 tttaagatca aaaacctcct cccacgcggc ggtgtcgagc tgctgccatt gagcaggcga 3240 gaaactggca aagggcggca gatgtacgtc atgttgcgaa aagaattgcc gtgtatggcc 3300 gagaatgtcg tttatagcgg agcgtttcat cgaaagcgtt ctccttagcg gtgaccgggc 3360 agctgcgccg cccggcgtgt ggacttattt caccgtccag cctttgtaat tgccgacgtt 3420 gtttttatcg atcatcgtca ccgggatcag caccggctct ttcggcgcag gtttgccctg 3480 caaaatgtcg tagccaattt ccaccgcttt cgctgccatc acctggggat cttgcgccgg 3540 agtagcgaca aacaacgagt tctcacgctt gagcgcctct tcggcgtccg ggcttccgtc 3600 cacaccgaca ataaagaact cgttacgttg tgcctgtttt gctgccagat cggcaccgat 3660 tgcggtggga tcgttaatcg caaatacgcc gtcgatcttc ggatttgccg ccagcagtcc 3720 cgtcattacc tccagcccgc cttcacgact gcctttcgcg ttctggttgt cagagagcac 3780 tttgatgtca ggatggcgtt taaattcagt ctggcatcct tcgacgcggt tttgcacggc 3840 ggataccggc gggccgttga tgatcaccac gttgcctttg cctttcaggc gatcggtgat 3900 gtatttacag gccatttcgc ctgcctgggt gttatcggaa gtgatggtgg catcggcacc 3960 ttctgccgct acgtcaaccg cgacgaccac gatcccggca tctttcgccc gtttcaccgc 4020 cgggccgatc ccttttgaat cggcagcgtt gaggataatc atatcgacgt tagcggcgat 4080 aaagttgtct atctgcgaca cctgctgacc cagatcgtag ccgctggaaa ccagcgtcac 4140 tttgacgtta tcgcctgcca gtttgcgtgc ttccagctcc gcgcctttgg tgatctgcac 4200 gaagaacggg ttcgccagat cgcccaccgt tacgcctatt gatttcagtt ctttcgcctg 4260 ggcgaacggt gctgcggcca gcagcgcgcc tgcacagagc gcggtcacta agggcttcaa 4320 tctcatgctg tattcctcat gtgtttatgc actttgatgg tgtcgggtac ggtatttgtc 4380 gatcagcacc gcaatgatga tcatcgcccc tttgatcacc agttgccaga agtaagagac 4440 gcccattaag gtcatgccat tgttgagcgt ggcgataatt agcgcgccga ccagcgtgcc 4500 ggtgatggtg ccgatgccgc cgacaaaact ggtgccgccg aggatcaccg ctgcaatggc 4560 atccagttcg taacccatgc ctaagttgcc gttggcgctg tacagccgtg aggcgctcat 4620 aatcccacca agcccagaaa gcaggccgct catgccataa acaaacagca gcaccagcca 4680 gaccttaatg ccggtaagac gcgccgcctg catattgccg ccgacggcgt agatatgaac 4740 gccaagcgtg gtgcggcgca gaataaacca gcacaccacg atcaccgcca gcgcaatcac 4800 caccagccat gggaccggcc cgagatagtt gttgcctatc cactcgaaat taatgttgga 4860 gttgataacc gtggtgccgt ccgccagcag atacgccgcc ccgcgcagcg ccgtataggt 4920 gccaagcgta acgataaacg gtggcaatcc ggcaaaggcc accagcgcgc cgttgaacag 4980 ccccagcagc aggccgagca tcagcgctgc cgggatcgac agcatggcga actcagggct 5040 aagggagacg accatcgccg ccaccgctgt ggtgccgagg atcgaaccca cggaaagatc 5100 gatcccgccg gtcaaaatga tgaaggtcat ccccgccgcc agaacaatgt tgatcgatgc 5160 ctggcgggta atattcagca ggttgctttc ggtaaaaaag tttggcgtga taaagccaaa 5220 taccgccacg atcagaatca aaatgggcaa gatgccgacc gtttgcatca gatcgctcat 5280 cagcattttt ttggcagagg tttttgcaga ggtcgtcatg aggttaccgc ctgggaatgg 5340 gcgtcgttga cgccagtcgc taaggtcata atgttttcct gggtgatgtt tttgccgttt 5400 aactcaccgg caatgctgcc ttcgcgcatc acatagacgc gatcgctcat tcccactatc 5460 tccggcagtt cgctggagat catcaggatc gccacgccct tgcgcgccat ctcgttcatg 5520 atccggtaga tctcactttt ggcgccaacg tccacgccgc gggcgggttc atcgagcagt 5580 aaaatgcgcg ggccaatcgc cacccagcgg gagatcaaca gtttttgctg attgccgccg 5640 gaaagcccgc ccgcgcgtac ctgggcatga ggcacgcgaa tgttgagcaa cttaatggcg 5700 tcatcggaaa tggtttgcgc ttttttgcga ttgagcattc cccagcgggc atcgcgctcc 5760 agggttgcca tggtgatgtt ttcggctgct gccatttcaa ggaataagcc ttgttctttg 5820 cggttttcgg tgagaaaacc aatgccaaga tcgatggctt cgcgcgggga gtggatcacc 5880 accggttcac catcgacttc aatcattccg cctgtcgctt tccgcacgcc gaagatcaac 5940 tgcgccagtt cggaacgtcc ggcacccacc agtccggcga ggccaacaat ttcgccggaa 6000 cgcaccagca ggctactcgg ctggactttg ccgccgtcgg tcaggtggtg aacattcagg 6060 cgggctttac cgagcgggat atcgcgctct ttattgaaca gatcgctcag tggcctgccg 6120 accatcatcc gcaccagctc cccggcattg aggttatcgc gggtcaggct gccaacgtat 6180 tgcccgtcgc gtagcacgct gacgcgatcg gaaagctcat acacttccgc catgcggtgg 6240 ctaatgtaga taatcgccat cccttcatcg cgcagccgca taatcagttc aaacaggcgg 6300 tgagtttcgc gggaggagag ggcagcggtg ggttcgtcca tcaccagaat gcggctgttg 6360 cgatgtagtg cgcgggcgat ttcgacctgc tgttgctcgg caatggtcag cgtcatgacc 6420 ttatcgctgg cgttaaactg cgcgccgagg cggtcgatca ctttttgcgc ctgcactagc 6480 atctctttac gctgcaccag cccgccgtgg gaaagctcgc tgccgagaaa aatattttct 6540 gccaccgaca gattcggtgc cagctgcatc tcctgataaa tcagcgtaat accggcgctt 6600 aaggcatctt ttggcgtgcg aatgtgaaag ggcttgccgt ctatgagaat ctcgccgctg 6660 gtggcggtat acgcccccgc cagcaccttc atcagcgtgc tttttcccgc gccgttttcc 6720 cccatcaggg catggatctc gccagggtag accgtcaaat ccaccccttt gagtgcataa 6780 aatttgccga aggctttggc aatattgcgc atctccagaa ctggcgtgct gttcatggtg 6840 gactcctgcg aggttgtcga tatcagcact ccatcacagg aaagtaaatg caaaatgtca 6900 gaagccgttc atatttgtca tattgcgatt tttcttcacg gagcgtgata tggcgcaccc 6960 cggacgtcac ttttttgcca gcgcgcgcgg gcgattgctg cttttgaatt tgctggtggt 7020 ggcggtgacg ttgatggtca gcggcgtggc ggtaatgggc tttcgtcatg ccagccagat 7080 gcaggagctg gtgcagcagc aaacggtgga tgatatgacc ggcagcctga atctggcgcg 7140 cgacacggca aacgtggcaa cggcggcggt gcgattgtcg caggtggtgg gagcgctgga 7200 atataaaggc gaagccgagc ggttgcagga gacacagcgg gcattaaaaa gctcgcttgc 7260 acaactggcg aacgcgcctt tagcgcagca ggaagccggg ctggtgacgc gaatcatcac 7320 gcgtagcaac gaactgcaaa ccagcgtcgg cggtatgctg gagcgcgggc aaaggcggca 7380 tctggagcgc aacgcgctgt taagttcgct gtatcaaaac ttaagttatc tgcggcatct 7440 gcaaaaagtc actcacgcgc aagatgatat tttgcttaac gagatgaacc gactgattgt 7500 tgccgctatt gccacccccg cgccgcaggc gattattcat caactggtcg gggtaatgtc 7560 tgcgttgccg acccacagcg atacgccatt ggttaatacg ttactcaatg atttcaatga 7620 tttcaatgat gaaatgcgta aactcgcgcc gctttctgcc gctctggagc aaagcgatct 7680 ggcaatcagc tggtatatgt ttcacatcaa agcgctggtg gcgatcctca atggcgacat 7740 caaccgttac gccgaacagg tggcgacgct ctccggtcag cgtgtggcgc aaagttacca 7800 ggatttgcgc tccggcgaga gggtgatcat gattttcgcc ctgttagcgg tggtgatcac 7860 cgcgtttgcc ggctggtata tctatcgcaa cctcggcact aacctgacgg cgatttcccg 7920 cgccatgagc cgcctggcgc acggcgaagc ggacgtcact tttccggcgt tacagcggcg 7980 tgatgagttg ggtgaactgg cgcgcgcctt taacgttttt gcccgcaata ccgcgtcact 8040 cgaacgaacc tcacggctgc taaaagagaa gaccacgcag atggagattg cccaaactga 8100 gcggcagggg ttggaagagg cgctattaca cagccagaaa ctgaaagctg tcgggcaact 8160 gacgggcggg ctggcccatg attttaataa tctgctggcg gtgattattg gcagcctgga 8220 gctggtgaat ccggactcgc cagacgcgcc gcgaatacag cgggcgctgc aagctgccga 8280 acgtggggcg ctactgacac aacgactgct ggcgttttcc cgcaagcagt ccttacatcc 8340 gcaagccgtt gaactgaaaa cattgctgga agagttaagc gaattaatgc gccactcctt 8400 accggcaacg ctggcgctgg agattgaagc gcagtctccg gcgtggcccg cgtggattga 8460 catcagccaa ctggaaaatg ccatcatcaa cctggtgatg aacgcccgtg acgcgatgga 8520 agggcagacg ggaatcatca aaattcgtac ctggaatcag cgcgttactc gcagcagtgg 8580 gcagcgtcag gacatggtgg cactggaggt catcgatcat ggctgcggta tgtcgcaggc 8640 ggtgaaaagc caggtatttg agccattctt taccaccaaa cagacgggca gcggcagcgg 8700 gctgggtttg tcgatggtct atggttttgt gcgccagtcc ggtgggcgcg ttgaaattga 8760 aagcgcgccg gggcagggga caacggtcag attacagctt ccccgcgcgc tgacggcggc 8820 gaaaaaccta tcgccagcgg cagtagaaca ggcttctgtc agcggcgata aactggtgtt 8880 agtgctggaa gatgaagccg cggtgcgcca gaccatctgc gaacagttgc acctgctggg 8940 ctatttgacg ctggaagcaa gcagcggcga acaggcgctg gatctgctgg cggcatcagc 9000 agaaatcgat atttttatca gcgatttaat gctccccggc ggcatgagcg gcgcagaagt 9060 ggtcaatgcg gcccgcaaac tttacccgca cctgacgctg ctactcatca gcggtcagga 9120 tttacgcccc agccataacc ccgcgctgcc agacgtggcg ctgttgcgca aaccctttac 9180 ccgtgcgcag ttggcgcagg cgctggggca agag 9214 <210> 1322 <211> 236 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(70..777) <400> 1322 Met Lys Pro Val Val Leu Val Val Asp Asp Asp Thr Ala Ile Cys Ala 1 5 10 15 Leu Leu Gln Asp Val Leu Ser Glu His Val Phe Thr Val Ser Val Cys 20 25 30 His Thr Gly Gln Glu Ala Ile Leu Arg Ile Glu Gly Asp Pro Asp Ile 35 40 45 Ala Leu Val Val Leu Asp Met Met Leu Pro Asp Thr Asn Gly Leu Arg 50 55 60 Val Leu Gln Gln Ile Gln Lys Leu Arg Pro Thr Leu Pro Val Val Met 65 70 75 80 Leu Thr Gly Met Gly Ser Glu Ser Asp Val Val Val Gly Leu Glu Met 85 90 95 Gly Ala Asp Asp Tyr Ile Cys Lys Pro Phe Thr Pro Arg Val Val Val 100 105 110 Ala Arg Leu Lys Ala Val Leu Arg Arg Val Gly Ala Leu Ala Val Asn 115 120 125 Asp Glu Lys Ser Ala Gly Leu Ser Phe Asn Gly Trp Tyr Leu Asp Thr 130 135 140 Met Arg Cys Gln Leu His Asn Pro Leu Gln Gln His Val Glu Leu Thr 145 150 155 160 Gln Gly Glu Tyr Gly Leu Leu Leu Ala Leu Ala Gln Asn Ala Arg Arg 165 170 175 Val Leu Ser Arg Glu Gln Leu Leu Ala Phe Thr His Ser Asp Ser Val 180 185 190 Glu Val Phe Asp Arg Thr Ile Asp Val Leu Ile Met Arg Leu Arg Arg 195 200 205 Lys Ile Glu Leu Asn Pro His Gln Pro Met Leu Ile Lys Thr Leu Arg 210 215 220 Gly Leu Gly Tyr Val Phe Ala Ala Asp Val His * 225 230 235 <210> 1323 <211> 334 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(774..1775) <400> 1323 Met Met Glu Arg Lys Gly Ile Ile Ala Ala Gly Asn Met Leu Val Asp 1 5 10 15 His Val His Gln Ile Ile Gln Trp Pro Glu Arg Gly Trp Leu Ala Glu 20 25 30 Ile Thr His Ser Glu Arg Ser Thr Gly Gly Ala Pro Leu Asn Val Leu 35 40 45 Leu Thr Leu Ala Lys Met Arg Thr Gly Leu Pro Leu Gln Ala Val Gly 50 55 60 Leu Ile Gly Gln Asp Ser Asp Gly Asp Tyr Ile Met Ala Met Leu Glu 65 70 75 80 Gln Tyr His Val Asn Arg Gln His Val Gln Arg Thr Thr Phe Ala Pro 85 90 95 Thr Ser Met Ser Gln Val Met Thr Asp Pro Ser Gly Gln Arg Thr Phe 100 105 110 Phe His Ser Pro Gly Ala Asn Arg Leu Leu Asp Leu Pro Ala Phe Asp 115 120 125 Gln Leu Asp Asn Thr Met Lys Ile Phe His Leu Gly Tyr Leu Leu Leu 130 135 140 Leu Asp Ser Leu Asp Met Pro Asp Asp Val Tyr Gly Thr Arg Ser Ala 145 150 155 160 Arg Leu Leu Ala Gln Met Arg Asp Thr Gly Phe Glu Thr Ser Leu Asp 165 170 175 Leu Val Ser Arg Lys Gly Asp Pro Arg Tyr Gln Pro Leu Val Leu Pro 180 185 190 Ala Leu Arg His Leu Asp Tyr Leu Val Ile Asn Glu Leu Glu Ala Gly 195 200 205 Glu Phe Ser Gly Leu Glu Ile Arg Leu Pro Asn Gly Glu Pro His Ile 210 215 220 Ala His Ile Ala Ala Ala Ala Arg Glu Leu Leu Asp Ala Gly Val Arg 225 230 235 240 Gln Arg Val Val Ile His Tyr Pro Glu Gly Ala Trp Gly Glu Thr Pro 245 250 255 Glu Gln Gly Gly Val Trp Ile Pro Ser Gln Lys Leu Glu Gln Arg Glu 260 265 270 Ile Ile Gly Ser Val Gly Ala Gly Asp Ala Phe Cys Ala Gly Phe Leu 275 280 285 Tyr Gly Cys His Glu Arg Trp Thr Leu Thr Glu Ser Ile Lys Leu Ala 290 295 300 His Ala Cys Ala Arg Ala Ser Leu Leu Cys Ala Asn Ala Ile Asp Gly 305 310 315 320 Ala Lys Thr Leu Glu Glu Leu Gln Thr Glu Met Ser Asp * 325 330 <210> 1324 <211> 287 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1772..2632) <400> 1324 Met Pro Leu Ile Ser Leu Ala Glu Gly Leu Ala His Ala Arg Glu His 1 5 10 15 His Tyr Ser Leu Gly Ala Phe Asn Val Leu Asp Ser His Phe Leu Arg 20 25 30 Ala Leu Phe Ala Ala Ala Arg Gln Glu Arg Ser Pro Phe Ile Ile Asn 35 40 45 Ile Ala Glu Val His Phe Lys Tyr Ile Ser Leu Asp Ser Leu Val Glu 50 55 60 Thr Val Lys Phe Glu Ala Ala Arg His Asp Ile Pro Val Val Leu Asn 65 70 75 80 Leu Asp His Gly Leu His Phe Glu Ser Val Val Gln Ala Leu Arg Leu 85 90 95 Gly Phe Ser Ser Val Met Phe Asp Gly Ser Thr Leu Gly Tyr Glu Glu 100 105 110 Asn Val Arg Gln Thr Arg Glu Val Val Lys Met Cys His Ala Val Gly 115 120 125 Val Ser Val Glu Ala Glu Leu Gly Ala Val Gly Gly Asp Glu Gly Gly 130 135 140 Ala Leu Tyr Gly His Ala Asp Glu Ser Leu Phe Thr Asp Pro Gln Leu 145 150 155 160 Ala Arg Asp Phe Val Asp Arg Thr Gly Ile Asp Ala Leu Ala Val Ala 165 170 175 Ile Gly Asn Ala His Gly Lys Tyr Arg Gly Glu Pro Lys Leu Asp Phe 180 185 190 Pro Arg Leu Asp Ala Ile Arg Gln Gln Ala Ala Ile Pro Leu Val Leu 195 200 205 His Gly Gly Ser Gly Ile Ser Asp Ala Asp Phe Arg Arg Ala Ile Glu 210 215 220 Leu Gly Ile His Lys Ile Asn Phe Tyr Thr Gly Met Ser Gln Ala Ala 225 230 235 240 Leu Ala Ala Val Glu Ala Arg Met Ala His Arg Gln Pro Met Tyr Asp 245 250 255 Glu Phe Ala Glu Leu Leu Leu Ala Val Glu Ala Ala Ile Ser Asp Thr 260 265 270 Val Ala Gln Gln Met Arg Ile Phe Gly Ser Ala Gly Gln Ala * 275 280 285 <210> 1325 <211> 228 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2647..3330) <400> 1325 Met Lys Arg Ser Ala Ile Asn Asp Ile Leu Gly His Thr Arg Gln Phe 1 5 10 15 Phe Ser Gln His Asp Val His Leu Pro Pro Phe Ala Ser Phe Ser Pro 20 25 30 Ala Gln Trp Gln Gln Leu Asp Thr Ala Ala Trp Glu Glu Val Phe Asp 35 40 45 Leu Lys Leu Gly Trp Asp Val Thr Ala Phe Gly Arg Asn Asn Phe Ala 50 55 60 Ala His Gly Leu Thr Leu Phe Thr Leu Arg Asn Gly Ser Ala Lys Gly 65 70 75 80 Met Pro Tyr Val Lys Cys Tyr Ala Glu Lys Ile Met His Val Arg Asp 85 90 95 Ala Gln Val Thr Pro Met His Phe His Trp Arg Lys Arg Glu Asp Ile 100 105 110 Ile Asn Arg Gly Gly Gly Asn Leu Ile Val Glu Leu Trp Asn Ala Asp 115 120 125 Ser Asn Glu Gln Thr Ala Asp Ser Asp Ile Thr Val Val Ile Asp Gly 130 135 140 Cys Arg Gln Lys His Thr Ala Gly Ser Gln Leu Arg Leu Ser Pro Gly 145 150 155 160 Glu Ser Ile Cys Leu Pro Pro Gly Leu Tyr His Ser Phe Trp Ala Glu 165 170 175 Ala Gly Phe Gly Asp Val Leu Val Gly Glu Val Ser Ser Val Asn Asp 180 185 190 Asp Asp His Asp Asn His Phe Leu Gln Pro Leu Asp Arg Tyr Asn Leu 195 200 205 Ile Asp Glu Asp Glu Pro Ala Gln Leu Val Leu Cys Asn Glu Tyr Arg 210 215 220 Gln Phe Arg * 225 <210> 1326 <211> 314 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3385..4326) <400> 1326 Met Arg Leu Lys Pro Leu Val Thr Ala Leu Cys Ala Gly Ala Leu Leu 1 5 10 15 Ala Ala Ala Pro Phe Ala Gln Ala Lys Glu Leu Lys Ser Ile Gly Val 20 25 30 Thr Val Gly Asp Leu Ala Asn Pro Phe Phe Val Gln Ile Thr Lys Gly 35 40 45 Ala Glu Leu Glu Ala Arg Lys Leu Ala Gly Asp Asn Val Lys Val Thr 50 55 60 Leu Val Ser Ser Gly Tyr Asp Leu Gly Gln Gln Val Ser Gln Ile Asp 65 70 75 80 Asn Phe Ile Ala Ala Asn Val Asp Met Ile Ile Leu Asn Ala Ala Asp 85 90 95 Ser Lys Gly Ile Gly Pro Ala Val Lys Arg Ala Lys Asp Ala Gly Ile 100 105 110 Val Val Val Ala Val Asp Val Ala Ala Glu Gly Ala Asp Ala Thr Ile 115 120 125 Thr Ser Asp Asn Thr Gln Ala Gly Glu Met Ala Cys Lys Tyr Ile Thr 130 135 140 Asp Arg Leu Lys Gly Lys Gly Asn Val Val Ile Ile Asn Gly Pro Pro 145 150 155 160 Val Ser Ala Val Gln Asn Arg Val Glu Gly Cys Gln Thr Glu Phe Lys 165 170 175 Arg His Pro Asp Ile Lys Val Leu Ser Asp Asn Gln Asn Ala Lys Gly 180 185 190 Ser Arg Glu Gly Gly Leu Glu Val Met Thr Gly Leu Leu Ala Ala Asn 195 200 205 Pro Lys Ile Asp Gly Val Phe Ala Ile Asn Asp Pro Thr Ala Ile Gly 210 215 220 Ala Asp Leu Ala Ala Lys Gln Ala Gln Arg Asn Glu Phe Phe Ile Val 225 230 235 240 Gly Val Asp Gly Ser Pro Asp Ala Glu Glu Ala Leu Lys Arg Glu Asn 245 250 255 Ser Leu Phe Val Ala Thr Pro Ala Gln Asp Pro Gln Val Met Ala Ala 260 265 270 Lys Ala Val Glu Ile Gly Tyr Asp Ile Leu Gln Gly Lys Pro Ala Pro 275 280 285 Lys Glu Pro Val Leu Ile Pro Val Thr Met Ile Asp Lys Asn Asn Val 290 295 300 Gly Asn Tyr Lys Gly Trp Thr Val Lys * 305 310 <210> 1327 <211> 325 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4345..5319) <400> 1327 Met Thr Thr Ser Ala Lys Thr Ser Ala Lys Lys Met Leu Met Ser Asp 1 5 10 15 Leu Met Gln Thr Val Gly Ile Leu Pro Ile Leu Ile Leu Ile Val Ala 20 25 30 Val Phe Gly Phe Ile Thr Pro Asn Phe Phe Thr Glu Ser Asn Leu Leu 35 40 45 Asn Ile Thr Arg Gln Ala Ser Ile Asn Ile Val Leu Ala Ala Gly Met 50 55 60 Thr Phe Ile Ile Leu Thr Gly Gly Ile Asp Leu Ser Val Gly Ser Ile 65 70 75 80 Leu Gly Thr Thr Ala Val Ala Ala Met Val Val Ser Leu Ser Pro Glu 85 90 95 Phe Ala Met Leu Ser Ile Pro Ala Ala Leu Met Leu Gly Leu Leu Leu 100 105 110 Gly Leu Phe Asn Gly Ala Leu Val Ala Phe Ala Gly Leu Pro Pro Phe 115 120 125 Ile Val Thr Leu Gly Thr Tyr Thr Ala Leu Arg Gly Ala Ala Tyr Leu 130 135 140 Leu Ala Asp Gly Thr Thr Val Ile Asn Ser Asn Ile Asn Phe Glu Trp 145 150 155 160 Ile Gly Asn Asn Tyr Leu Gly Pro Val Pro Trp Leu Val Val Ile Ala 165 170 175 Leu Ala Val Ile Val Val Cys Trp Phe Ile Leu Arg Arg Thr Thr Leu 180 185 190 Gly Val His Ile Tyr Ala Val Gly Gly Asn Met Gln Ala Ala Arg Leu 195 200 205 Thr Gly Ile Lys Val Trp Leu Val Leu Leu Phe Val Tyr Gly Met Ser 210 215 220 Gly Leu Leu Ser Gly Leu Gly Gly Ile Met Ser Ala Ser Arg Leu Tyr 225 230 235 240 Ser Ala Asn Gly Asn Leu Gly Met Gly Tyr Glu Leu Asp Ala Ile Ala 245 250 255 Ala Val Ile Leu Gly Gly Thr Ser Phe Val Gly Gly Ile Gly Thr Ile 260 265 270 Thr Gly Thr Leu Val Gly Ala Leu Ile Ile Ala Thr Leu Asn Asn Gly 275 280 285 Met Thr Leu Met Gly Val Ser Tyr Phe Trp Gln Leu Val Ile Lys Gly 290 295 300 Ala Met Ile Ile Ile Ala Val Leu Ile Asp Lys Tyr Arg Thr Arg His 305 310 315 320 His Gln Ser Ala * <210> 1328 <211> 507 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5316..6836) <400> 1328 Met Asn Ser Thr Pro Val Leu Glu Met Arg Asn Ile Ala Lys Ala Phe 1 5 10 15 Gly Lys Phe Tyr Ala Leu Lys Gly Val Asp Leu Thr Val Tyr Pro Gly 20 25 30 Glu Ile His Ala Leu Met Gly Glu Asn Gly Ala Gly Lys Ser Thr Leu 35 40 45 Met Lys Val Leu Ala Gly Ala Tyr Thr Ala Thr Ser Gly Glu Ile Leu 50 55 60 Ile Asp Gly Lys Pro Phe His Ile Arg Thr Pro Lys Asp Ala Leu Ser 65 70 75 80 Ala Gly Ile Thr Leu Ile Tyr Gln Glu Met Gln Leu Ala Pro Asn Leu 85 90 95 Ser Val Ala Glu Asn Ile Phe Leu Gly Ser Glu Leu Ser His Gly Gly 100 105 110 Leu Val Gln Arg Lys Glu Met Leu Val Gln Ala Gln Lys Val Ile Asp 115 120 125 Arg Leu Gly Ala Gln Phe Asn Ala Ser Asp Lys Val Met Thr Leu Thr 130 135 140 Ile Ala Glu Gln Gln Gln Val Glu Ile Ala Arg Ala Leu His Arg Asn 145 150 155 160 Ser Arg Ile Leu Val Met Asp Glu Pro Thr Ala Ala Leu Ser Ser Arg 165 170 175 Glu Thr His Arg Leu Phe Glu Leu Ile Met Arg Leu Arg Asp Glu Gly 180 185 190 Met Ala Ile Ile Tyr Ile Ser His Arg Met Ala Glu Val Tyr Glu Leu 195 200 205 Ser Asp Arg Val Ser Val Leu Arg Asp Gly Gln Tyr Val Gly Ser Leu 210 215 220 Thr Arg Asp Asn Leu Asn Ala Gly Glu Leu Val Arg Met Met Val Gly 225 230 235 240 Arg Pro Leu Ser Asp Leu Phe Asn Lys Glu Arg Asp Ile Pro Leu Gly 245 250 255 Lys Ala Arg Leu Asn Val His His Leu Thr Asp Gly Gly Lys Val Gln 260 265 270 Pro Ser Ser Leu Leu Val Arg Ser Gly Glu Ile Val Gly Leu Ala Gly 275 280 285 Leu Val Gly Ala Gly Arg Ser Glu Leu Ala Gln Leu Ile Phe Gly Val 290 295 300 Arg Lys Ala Thr Gly Gly Met Ile Glu Val Asp Gly Glu Pro Val Val 305 310 315 320 Ile His Ser Pro Arg Glu Ala Ile Asp Leu Gly Ile Gly Phe Leu Thr 325 330 335 Glu Asn Arg Lys Glu Gln Gly Leu Phe Leu Glu Met Ala Ala Ala Glu 340 345 350 Asn Ile Thr Met Ala Thr Leu Glu Arg Asp Ala Arg Trp Gly Met Leu 355 360 365 Asn Arg Lys Lys Ala Gln Thr Ile Ser Asp Asp Ala Ile Lys Leu Leu 370 375 380 Asn Ile Arg Val Pro His Ala Gln Val Arg Ala Gly Gly Leu Ser Gly 385 390 395 400 Gly Asn Gln Gln Lys Leu Leu Ile Ser Arg Trp Val Ala Ile Gly Pro 405 410 415 Arg Ile Leu Leu Leu Asp Glu Pro Ala Arg Gly Val Asp Val Gly Ala 420 425 430 Lys Ser Glu Ile Tyr Arg Ile Met Asn Glu Met Ala Arg Lys Gly Val 435 440 445 Ala Ile Leu Met Ile Ser Ser Glu Leu Pro Glu Ile Val Gly Met Ser 450 455 460 Asp Arg Val Tyr Val Met Arg Glu Gly Ser Ile Ala Gly Glu Leu Asn 465 470 475 480 Gly Lys Asn Ile Thr Gln Glu Asn Ile Met Thr Leu Ala Thr Gly Val 485 490 495 Asn Asp Ala His Ser Gln Ala Val Thr Ser * 500 505 <210> 1329 <211> 9179 <212> DNA <213> Escherichia coli O157:H7 <400> 1329 agcggcacgc tggattgaac aaatccctgg gccggtttat ccccgctggc gcggggaaca 60 caaaccgaaa cacacgatca atccgaatat gagcggttta tccccgctgg cgcggggaac 120 actttggtga cagtttttgt cactgttttg gtgacggttt atccccgctg gcgcggggaa 180 cacactaagc atacatatct gtttttaaac aaatttattc cacatcaaca atctaccaac 240 taaattcaaa catttcctta tttttaaaga acacataacc tattgattat caacaggaag 300 aaaagaaacc aaacgtaacc catccaaatc caccggaata cgtctgtttt ctccccaggt 360 ctgaaattca aaacccgact cggtattggt cgcccaggcc atcaccacat ttccgcaacc 420 agccagttgg gtaatttgct gccagatcat ctcccgaata cgttttgatg tatcaccaac 480 atacacaccg gcacgcactt ccagtagcca gattgcgagc cgtccacgta agcgcggagg 540 gacattttct gtaacaacca cgaccatgct catccgccgc gcccccggtg accactatca 600 cccagcgttt caggttcagg gatggcaggc ggtaacatat ccggcgcggg ttgtggtggt 660 tcaatttcac ctgcagcaag gactttctca attaacggta ttaatttgcc cgttaactta 720 gtgctacgga aaatatcgcg acaggctaat ctgacttctt tatcaggttc tgcgggttgc 780 ctcgctgcta tttcaaatgc ctttggcaca accgaatcaa atttaatgat atcggctatg 840 tcataaacaa atgaaagcgg tttgccacta tgaataaatc caatagcggg cgcatatccc 900 gcggctaata ctgccgcttc agaaataccg tacagacatg atgtggcagc actgatgcag 960 cgattcacaa catcgccttt ttcccagtct ttaggatcgt atttgcgacc attccatttc 1020 acaccatatt gtttcgccag taatgcatag gtctggcgaa cgcgggatcc ctcaattccc 1080 cgtagctgat ccactgaacg gcgagctggc ggtggctcac gaaaacgtaa ttcatacatt 1140 ttgcgcacca ccttcaggcg tagatcttcc gttaaagcca gctttgcctg gtagagtaat 1200 ttatctgccc gcgcccctcc gggttgtccg gaagagtaaa cgcgaacgcc cgcttcaccg 1260 acccagacca gcagtgttcc caccgtggcg gccagatgca ccgccgcgtg ggaaactctc 1320 gttcccggtt cgagcataat gcaggcgacc gatcccaccg gaatgtgcgt gcggatcccg 1380 gttttgtcga tcagcacgaa agcgccgtcc agtacgtcga tttgaccgta ctggaggaag 1440 atcatagagg tgcgatcttt taacgggatc ggactcagtg gtacaaacgt cacacctctg 1500 ctccgggttt gatcagcatc agaccacagc cgaacgcgcg gcttttgcca tacccctgac 1560 tgagacgttg cagaaataac ccgggatcgg tgaccgtaag catccccgta taatccacgc 1620 tactgaactg gatcagttgc cgggagtttt cccgccgcag ttgctgttgt cggtaggcat 1680 caaccgaggt atccagcagt gtaaaaccgc ttctctcccc ctgcgctgcc agccagtcca 1740 gcgccgcctg ttgttgatgc aaccagacat cacttccttc cgcctgcccc ctcacctgcc 1800 gtttcgcctc catcagcaga tcgtggcgct tgcccgcttt acagattgtt ggattcgccc 1860 gcaggttgaa acaaagttgt tgtccggtac gcagctcggg cacaaatgac cggcattcga 1920 tggtgaacgt ttcactttcc gccgggcgtt cctgcgacag tacaaaaaag cgaaacgcgc 1980 cctggagttc ttcccgacga taaagaaatt gcctttcttt gccgccaggg aagagatccc 2040 acagccactg atgcatcaca tattccccgc gatccaccaa atgcagcaac tgcgcaggcg 2100 aaagctggcc ggtatgtaag gttattcttg agaggtacat ggttcctcct tgctgagcca 2160 cggcccctga ttgatggtgc gttccccaaa cagccactgc tgacgattta aaggaacatc 2220 ccggcgacgt aatattttgc tcgcgaccag gccgtcgtgt tccccttccc accagcattc 2280 atcctgaagt ttcgggagtg agactttcag ttcgcggaaa ctatcctgat actgttggta 2340 tgcgttacgt aagacatcag acgcgttgcc ttcgagcagt aacggcgcaa gtggtaacgc 2400 cagcggatga ctttttcgcc ccagataaag cggaaaaacc ggatgacgta aaccgtcctg 2460 caactgttca aggctgtaag gcgcatcggg ggttgttgcc accgccacca tccaccaggc 2520 atcggtgtag tagtcgcgcc gggagataat cgcgctcaga agatcagggg cgctcaactc 2580 ttcgcgacgg ctgaaataac gcgctttacg cacctctttt ggcatctgga ccgtgtgata 2640 atcccgtgcc cagcgcgggt tacggctggc gcaaaccacc agtgaatagt ggcggttaaa 2700 cgcgtttaat cgttcggtat catcacgccg aatccctacc ccggcagcca gcagccccag 2760 caatgctgag cgcgaaggca gttcatgggt atgacgcact tcgccggggg catcgacgcc 2820 ccaggatgcc attggcccat gaagctgaaa aatcaaatat tggctcatta gccgcccctt 2880 acgcgcagat aaagtccagc acgtccttca tgcttccctg tttgttcatc acgtcaaagc 2940 ttgcgcattc ggtcttctgt tcatagaccg tattcatatt ttcgcgaagc gttgtaatac 3000 gctgcaccgc cacatctaac tgccgggtgc cattaatggg ttcatagaaa gccgccgcca 3060 gagaacgtgg ttgttcggtg cctttttctg ccagcgccca ggaggcgtag gcacggctgg 3120 caaagctgtt ctgtttgccg gttggggaga ctttaagtgc ggcttccgta aaggcgcgca 3180 aggtctgatt agctaacgct tcgtcaccgc cgaggttttc gaccagcaga tctttatcga 3240 tgcagatata ggtgtagaac agcgcagaac cgaatccggt ttcaccaaga tgcccggcac 3300 cggcatcttc agaagcctgg cgcaaatcat caacggcggt gaaaaaatca tcttcgacaa 3360 tcgtttcact gacaccaaat gcatgcgcga cctggcaggc ggcttcaaca ttaaattcgg 3420 gtttattcgc cagcatacga ccaaacatag cgatatctac tgccatgcga tctttacgta 3480 acaaagcgag atcttcctct tttggcgcgc gcttttcttc ggccagttga tgggccagcg 3540 cttttacggc gtcaaattct gccgggctga tatggactaa ttgttcagtt tcggcgttag 3600 tgagcggatc ttttggtttt ttgtcgtttt tagctttccc aagataatcc gcaatttttg 3660 ccgcccattc gatggctttt ttctcttcga tgcctttctc aatcaggata gttgccgcct 3720 cacgcgcaat acgcccactg cgaataccaa tatggcccgc cagtgcctgt tcaaaaagtg 3780 cagaagtgcg ccacgcacgt ttcagacttt gcgaggaaac gcgcagtcgc gttgctccac 3840 ccaggaccac ggttttcggc gctccggtgt catcacggtt aaggttggct gcagggtaag 3900 cggttaacaa atgaagctga ataaatgtcg tcatgagata gtcctttatt gattttgttc 3960 gttatcgacg tcgccagcct ggtaatattc cagcgcccag cggatacgga taaattcggt 4020 tggccgctga tgacggcggt gatgattgag cagatcgtcg ctctcctggc accagcggaa 4080 gacaccctct gccagagagt caagattaac ggaaccgttt aataatctga ctacgcggcg 4140 taactggcgc agtaattcat ccggtgtttt tactgccgac aggcgagtaa aacgcccctt 4200 tgacattacc gccgccagct gcgcagcaaa aggcagccgt tcatcaatgg ctttaacatt 4260 agcgctaagt gcggctatca gcgccagtgc ggtaatacgc cattcaggtt catcctgcca 4320 ctttatttgt ctgttcttca gaaacaggcg aaatccatcc gtcagacaaa catcattaac 4380 cgtcgtacta cgccgcagac tggcacgttc gccgcgtttc tcctgcaatt cctcatgcca 4440 tttgcgcagc gtggctttgt gctcctcttt tacaatactc attcagcagc ctcctgcttt 4500 ttctccctgg cggctttagc actttgcttc tccgccgatg ttgtaaaata tttcttgcgc 4560 gcggtcatga cgcgttccaa atcaacgggc tcataaggat tggtgaatac acgctcgtca 4620 aaatcctgac gtgcgaataa ccaaatttcc ttttgccatt tgccgagtaa ttcatccgca 4680 tcctgacctt cttcaatttg gcgcactaac ctcaggaagc gatgctgagt tttgttccag 4740 aagtcgatat ccacaaaact gaaatcaccc cttgcacctt ttggatcgga gaaccatgct 4800 tctttcaatg cactccgtaa cagactcaga atccgtgaag ccgtttgcgc agccagccgc 4860 agcttcggta tctggccttc ttttttattg agcagcagcg ggaaatggtg ttcgtaccaa 4920 cagcgcgctt tcatgttgtc gaaatcataa ccaaatcccc acaggcccac ttttgcctgt 4980 ttcagactgc tggcattaaa gagtttcacc accagcgcgg gaagttccgt attgttttct 5040 gacttacccg tttcgataag gcctaaccag tcgcgccaga ttaaaccgcc cggttgtggt 5100 ttaacggagt aaaactcacc gccctcttta agtggtacac ggtaaggcgt taagggatgc 5160 tgccacatgg cataattcgc accgtaattt ttggtagtca tcaaactcag aagcgcgtca 5220 ctctgctcac cgcaaatatc gcagttgccg actgtcgtgg tattaaaatc aatacgaata 5280 cgccgcggca ttccccagta cgcctggagt ttattgacct gatcatcggt taccaccgca 5340 ccggccagtt cgctggtacg cgtcgggcca agccagggga aaaccagatc gtcaaatttt 5400 ttgggtagcg gtaagtcggc ttcatcctgc ggcatcacgt tgagccacag tttgcgccac 5460 aagggggctt gttgattgcc ctgatactcc tgcaattcaa tcagagtcgt catcggccca 5520 ccgccgcgta aaccggtgcg atagcctttg ccacctgacg gcgcatttaa ctgtagggag 5580 aacagagcta acgcagaaca atgagagcat acgtgttcag tcacgccacg cttaataaag 5640 tggtctttat taaacttcgt tgtttgagcg ccgggaatct caggcagtag cgaagcgacc 5700 tgaactttat cgcccatgag cacctcgaaa tcctgcataa atgaaggtga atctgggcca 5760 aactggaaag ggtgttctaa tgacagcaat gcttcccgta gcttttcagc ttccagcccg 5820 tcttcccaga tatcatccca acgacgataa tcttttggcg cgaaactgct ttgtagtaac 5880 cccagcaaaa actgccatgc cgccccctgg agatctgccc gcggcgcagc gatatcgaca 5940 acattttcat ccgccagatc gactggcgcc agcttgcctg ttgttccgtc tttaaaacga 6000 acgggcaacc acggggttgt cagaagtgaa aacgagttca tatgtatcct ctcgtaaaaa 6060 agaccatccc tggtcggttg tccatcattc catccttttc ggtgtatcaa ctattcagag 6120 agtcctgtcg caggtatctc aatcaacctt gccaatcaat ccctccctgg ccgaataccc 6180 gcaactttcg tcatcagtga ctaaaatcac gtttgccatt tccggatctt gccgctgttc 6240 aatgcaccac tgcctgaacg cttccccttc cagtaaagaa aactcatccc gatgtttttt 6300 ccaccagctt cgacgcactc tgacaacgct catttcccat gcgtgagcac cggtggcata 6360 aggcttcacc acaccggcaa tacaggtagc cagccacagg gaaacagatt cctcagccag 6420 acgtgtcgac agcttttccg gaaggtaatc gttgatattg gcggcatagc caggcttgaa 6480 gttcaggaca aactttttag ccattgcgcg atcgcagtaa tatttgccca cttgctcctg 6540 ctcgctgcgg gcaaatcctt ccggcattac cacgtcctca ccgtagactg attcaataag 6600 aaggcgggct gcgtgtggca tttgaatagc gccttgctca cgcagtacac gctgcgtcag 6660 ccagattcgt ccatgatcgg gatagacata tgcactgtta cgcatggcac tgccgaacca 6720 ttcgtcacca ggagcgtcgt cccagacggg ggccagaatc agcaattcag gaggggaacg 6780 ctcgtctttt ccgtcacgct ttaactgacc attaatatcg cggatatgcc gctgtaatcg 6840 ccccgctcgc tgaatcagca aatcaacagg ggccaggtcg gagatcattt cgtccaggtc 6900 acaatcaacg ctctgctcta agacctgagt acaaatgagg acttttccgg cacgctgtga 6960 accgtcttct ttaccaaagc gtgccagcgt ctccatttca attcgctggc gatcgctaaa 7020 agcaaagcgg ctatgaaaga gtgaaaggct ggaagcggga atgacgccgc gggcaagcag 7080 ctgacgatga accttaatag cgtcatcgac agaattccgg atccaggcga tgcattttcc 7140 ctgacttacc gccgattcga tacgcgcaat actctcttgt tcactatgaa gccaacccac 7200 gctgacgcta cgctcaacgt ctttgcgcgt cgctacccgg tgtgagttca catcggattt 7260 cgtgacatgc gtcagccagg ggtaatcatc cttttcaagg aacggagctt cttgctggcc 7320 ctctgtgcca cgcgcaaagg cggcgacgag tttgtcgcgc tgctgttggg ataacgtagc 7380 agaaagcaaa atgacgctgt ttccgccacg cgcctgccgc tcgatcagcc cttcaagaat 7440 gcacgacatg taagcatcac aggcatggat ctcatcagcc agcaggattt tgttactcaa 7500 ccccagaagc cgcagattat tatgtttaaa cggcatcact gccatcatcg cctgatccag 7560 cgtgccgacg ccaatttcag ccagtagcgc cttcttgtta ctgttggcaa accaggccgc 7620 acatccctga ctgaatgttt gttcatccgg ttcttctgac ccgactaaat caccggacca 7680 gagtgattca ttgaagcggt ccattaatgt gcgggcactg tgtgccagca ccaagctggg 7740 gcgggactct ggcgaataga aagcaagcca ggttttgacc agccgatcgt acatggcatt 7800 ggccgttgcc attgttggca ggccaaaaaa caaaccctgt gctttcctcg cagccatcaa 7860 cctgtgcgcc aggataagcg ccgcttctgt tttacctgcg ccagtcacgt cttccagaat 7920 aaataactgt ggccctggct ggctgatatc cagatccagt accttttgct gtaatggtgt 7980 cgggtgctca ataaaaggaa acagcgtatt aattccggtg aaaggtgcgg tttctgcttt 8040 tggaggaaag acggttaagg cgttttgagc ctgaactaaa gttttctgcc agtaatcttt 8100 aatatccatt gggtgtgcga cgcgtggaaa aaatcgcgtt gacgaacccg tccagtctgc 8160 gagtacgact gttgcagaga tataccagga aagttgtttt aaaagttcaa cgccctcgtc 8220 atcatcccag aatgtgggaa tctctatgag cggaaacagt gccttgattt caaggagaaa 8280 atctcgcgcg gcagctttgt cttcaggcag aaaattatcc agctcatcaa tacggtcagg 8340 tggtcgacca tgatgcccgg tagttatgga catccacatc tctattacac gtgtaagttt 8400 acgagaagag agtgaagatg aaggaagcaa ctcctcacat tcacttaaat aataattcca 8460 cagccagtaa cccagcgttg aatgagagat cttttcgtaa ttctttctgg aaccttccgg 8520 aatcttgagt tcaggggcca ggtaaagttg ctgaaaagag cgggcaaatt ttccaatatc 8580 gtgccagcac agcaaccaag cgaaaaattg agccgcctgt tccttgtcag aaatccctaa 8640 ttgacgaaag taatcagcca gcccgaagca atttctttta accattaaat agcccattgc 8700 ggccacatcc agcgaatgcc agcaaagaag gtgatagccg tcgccaccct ctttctcgcc 8760 acgtcgggtt tttccccaga aatcaaagaa agtcacaata tttttatcct tcagtaaact 8820 taaaggatat ttacgcatat tttaaaaatt atctgtgata tatatcagcc aataaacatt 8880 tatattatga ataaattaat gattttcatt tgaaattcat aatgataaat agagactata 8940 tattcacata aaaaatataa atttaaaaaa gggtacagga gaccaaacca tcacaattca 9000 atacgcgggg ttttaccccc gcgtggtggc tacttcttcg attcgtaagc gagaactgcc 9060 ttaaactcca taccacgctc tctgatactc aactcacata acgagtcgcc taccatgagc 9120 gtgaatccca gtactgtaca acacagtact atgattgcca caagggcata ttttgttag 9179 <210> 1330 <211> 98 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(280..573) <400> 1330 Met Ser Met Val Val Val Val Thr Glu Asn Val Pro Pro Arg Leu Arg 1 5 10 15 Gly Arg Leu Ala Ile Trp Leu Leu Glu Val Arg Ala Gly Val Tyr Val 20 25 30 Gly Asp Thr Ser Lys Arg Ile Arg Glu Met Ile Trp Gln Gln Ile Thr 35 40 45 Gln Leu Ala Gly Cys Gly Asn Val Val Met Ala Trp Ala Thr Asn Thr 50 55 60 Glu Ser Gly Phe Glu Phe Gln Thr Trp Gly Glu Asn Arg Arg Ile Pro 65 70 75 80 Val Asp Leu Asp Gly Leu Arg Leu Val Ser Phe Leu Pro Val Asp Asn 85 90 95 Gln * <210> 1331 <211> 308 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(570..1493) <400> 1331 Val Thr Phe Val Pro Leu Ser Pro Ile Pro Leu Lys Asp Arg Thr Ser 1 5 10 15 Met Ile Phe Leu Gln Tyr Gly Gln Ile Asp Val Leu Asp Gly Ala Phe 20 25 30 Val Leu Ile Asp Lys Thr Gly Ile Arg Thr His Ile Pro Val Gly Ser 35 40 45 Val Ala Cys Ile Met Leu Glu Pro Gly Thr Arg Val Ser His Ala Ala 50 55 60 Val His Leu Ala Ala Thr Val Gly Thr Leu Leu Val Trp Val Gly Glu 65 70 75 80 Ala Gly Val Arg Val Tyr Ser Ser Gly Gln Pro Gly Gly Ala Arg Ala 85 90 95 Asp Lys Leu Leu Tyr Gln Ala Lys Leu Ala Leu Thr Glu Asp Leu Arg 100 105 110 Leu Lys Val Val Arg Lys Met Tyr Glu Leu Arg Phe Arg Glu Pro Pro 115 120 125 Pro Ala Arg Arg Ser Val Asp Gln Leu Arg Gly Ile Glu Gly Ser Arg 130 135 140 Val Arg Gln Thr Tyr Ala Leu Leu Ala Lys Gln Tyr Gly Val Lys Trp 145 150 155 160 Asn Gly Arg Lys Tyr Asp Pro Lys Asp Trp Glu Lys Gly Asp Val Val 165 170 175 Asn Arg Cys Ile Ser Ala Ala Thr Ser Cys Leu Tyr Gly Ile Ser Glu 180 185 190 Ala Ala Val Leu Ala Ala Gly Tyr Ala Pro Ala Ile Gly Phe Ile His 195 200 205 Ser Gly Lys Pro Leu Ser Phe Val Tyr Asp Ile Ala Asp Ile Ile Lys 210 215 220 Phe Asp Ser Val Val Pro Lys Ala Phe Glu Ile Ala Ala Arg Gln Pro 225 230 235 240 Ala Glu Pro Asp Lys Glu Val Arg Leu Ala Cys Arg Asp Ile Phe Arg 245 250 255 Ser Thr Lys Leu Thr Gly Lys Leu Ile Pro Leu Ile Glu Lys Val Leu 260 265 270 Ala Ala Gly Glu Ile Glu Pro Pro Gln Pro Ala Pro Asp Met Leu Pro 275 280 285 Pro Ala Ile Pro Glu Pro Glu Thr Leu Gly Asp Ser Gly His Arg Gly 290 295 300 Arg Gly Gly * 305 <210> 1332 <211> 217 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1490..2140) <400> 1332 Met Tyr Leu Ser Arg Ile Thr Leu His Thr Gly Gln Leu Ser Pro Ala 1 5 10 15 Gln Leu Leu His Leu Val Asp Arg Gly Glu Tyr Val Met His Gln Trp 20 25 30 Leu Trp Asp Leu Phe Pro Gly Gly Lys Glu Arg Gln Phe Leu Tyr Arg 35 40 45 Arg Glu Glu Leu Gln Gly Ala Phe Arg Phe Phe Val Leu Ser Gln Glu 50 55 60 Arg Pro Ala Glu Ser Glu Thr Phe Thr Ile Glu Cys Arg Ser Phe Val 65 70 75 80 Pro Glu Leu Arg Thr Gly Gln Gln Leu Cys Phe Asn Leu Arg Ala Asn 85 90 95 Pro Thr Ile Cys Lys Ala Gly Lys Arg His Asp Leu Leu Met Glu Ala 100 105 110 Lys Arg Gln Val Arg Gly Gln Ala Glu Gly Ser Asp Val Trp Leu His 115 120 125 Gln Gln Gln Ala Ala Leu Asp Trp Leu Ala Ala Gln Gly Glu Arg Ser 130 135 140 Gly Phe Thr Leu Leu Asp Thr Ser Val Asp Ala Tyr Arg Gln Gln Gln 145 150 155 160 Leu Arg Arg Glu Asn Ser Arg Gln Leu Ile Gln Phe Ser Ser Val Asp 165 170 175 Tyr Thr Gly Met Leu Thr Val Thr Asp Pro Gly Leu Phe Leu Gln Arg 180 185 190 Leu Ser Gln Gly Tyr Gly Lys Ser Arg Ala Phe Gly Cys Gly Leu Met 195 200 205 Leu Ile Lys Pro Gly Ala Glu Val * 210 215 <210> 1333 <211> 249 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2122..2868) <400> 1333 Met Ser Gln Tyr Leu Ile Phe Gln Leu His Gly Pro Met Ala Ser Trp 1 5 10 15 Gly Val Asp Ala Pro Gly Glu Val Arg His Thr His Glu Leu Pro Ser 20 25 30 Arg Ser Ala Leu Leu Gly Leu Leu Ala Ala Gly Val Gly Ile Arg Arg 35 40 45 Asp Asp Thr Glu Arg Leu Asn Ala Phe Asn Arg His Tyr Ser Leu Val 50 55 60 Val Cys Ala Ser Arg Asn Pro Arg Trp Ala Arg Asp Tyr His Thr Val 65 70 75 80 Gln Met Pro Lys Glu Val Arg Lys Ala Arg Tyr Phe Ser Arg Arg Glu 85 90 95 Glu Leu Ser Ala Pro Asp Leu Leu Ser Ala Ile Ile Ser Arg Arg Asp 100 105 110 Tyr Tyr Thr Asp Ala Trp Trp Met Val Ala Val Ala Thr Thr Pro Asp 115 120 125 Ala Pro Tyr Ser Leu Glu Gln Leu Gln Asp Gly Leu Arg His Pro Val 130 135 140 Phe Pro Leu Tyr Leu Gly Arg Lys Ser His Pro Leu Ala Leu Pro Leu 145 150 155 160 Ala Pro Leu Leu Leu Glu Gly Asn Ala Ser Asp Val Leu Arg Asn Ala 165 170 175 Tyr Gln Gln Tyr Gln Asp Ser Phe Arg Glu Leu Lys Val Ser Leu Pro 180 185 190 Lys Leu Gln Asp Glu Cys Trp Trp Glu Gly Glu His Asp Gly Leu Val 195 200 205 Ala Ser Lys Ile Leu Arg Arg Arg Asp Val Pro Leu Asn Arg Gln Gln 210 215 220 Trp Leu Phe Gly Glu Arg Thr Ile Asn Gln Gly Pro Trp Leu Ser Lys 225 230 235 240 Glu Glu Pro Cys Thr Ser Gln Glu * 245 <210> 1334 <211> 352 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2879..3934) <400> 1334 Met Thr Thr Phe Ile Gln Leu His Leu Leu Thr Ala Tyr Pro Ala Ala 1 5 10 15 Asn Leu Asn Arg Asp Asp Thr Gly Ala Pro Lys Thr Val Val Leu Gly 20 25 30 Gly Ala Thr Arg Leu Arg Val Ser Ser Gln Ser Leu Lys Arg Ala Trp 35 40 45 Arg Thr Ser Ala Leu Phe Glu Gln Ala Leu Ala Gly His Ile Gly Ile 50 55 60 Arg Ser Gly Arg Ile Ala Arg Glu Ala Ala Thr Ile Leu Ile Glu Lys 65 70 75 80 Gly Ile Glu Glu Lys Lys Ala Ile Glu Trp Ala Ala Lys Ile Ala Asp 85 90 95 Tyr Leu Gly Lys Ala Lys Asn Asp Lys Lys Pro Lys Asp Pro Leu Thr 100 105 110 Asn Ala Glu Thr Glu Gln Leu Val His Ile Ser Pro Ala Glu Phe Asp 115 120 125 Ala Val Lys Ala Leu Ala His Gln Leu Ala Glu Glu Lys Arg Ala Pro 130 135 140 Lys Glu Glu Asp Leu Ala Leu Leu Arg Lys Asp Arg Met Ala Val Asp 145 150 155 160 Ile Ala Met Phe Gly Arg Met Leu Ala Asn Lys Pro Glu Phe Asn Val 165 170 175 Glu Ala Ala Cys Gln Val Ala His Ala Phe Gly Val Ser Glu Thr Ile 180 185 190 Val Glu Asp Asp Phe Phe Thr Ala Val Asp Asp Leu Arg Gln Ala Ser 195 200 205 Glu Asp Ala Gly Ala Gly His Leu Gly Glu Thr Gly Phe Gly Ser Ala 210 215 220 Leu Phe Tyr Thr Tyr Ile Cys Ile Asp Lys Asp Leu Leu Val Glu Asn 225 230 235 240 Leu Gly Gly Asp Glu Ala Leu Ala Asn Gln Thr Leu Arg Ala Phe Thr 245 250 255 Glu Ala Ala Leu Lys Val Ser Pro Thr Gly Lys Gln Asn Ser Phe Ala 260 265 270 Ser Arg Ala Tyr Ala Ser Trp Ala Leu Ala Glu Lys Gly Thr Glu Gln 275 280 285 Pro Arg Ser Leu Ala Ala Ala Phe Tyr Glu Pro Ile Asn Gly Thr Arg 290 295 300 Gln Leu Asp Val Ala Val Gln Arg Ile Thr Thr Leu Arg Glu Asn Met 305 310 315 320 Asn Thr Val Tyr Glu Gln Lys Thr Glu Cys Ala Ser Phe Asp Val Met 325 330 335 Asn Lys Gln Gly Ser Met Lys Asp Val Leu Asp Phe Ile Cys Ala * 340 345 350 <210> 1335 <211> 179 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3946..4482) <400> 1335 Met Ser Ile Val Lys Glu Glu His Lys Ala Thr Leu Arg Lys Trp His 1 5 10 15 Glu Glu Leu Gln Glu Lys Arg Gly Glu Arg Ala Ser Leu Arg Arg Ser 20 25 30 Thr Thr Val Asn Asp Val Cys Leu Thr Asp Gly Phe Arg Leu Phe Leu 35 40 45 Lys Asn Arg Gln Ile Lys Trp Gln Asp Glu Pro Glu Trp Arg Ile Thr 50 55 60 Ala Leu Ala Leu Ile Ala Ala Leu Ser Ala Asn Val Lys Ala Ile Asp 65 70 75 80 Glu Arg Leu Pro Phe Ala Ala Gln Leu Ala Ala Val Met Ser Lys Gly 85 90 95 Arg Phe Thr Arg Leu Ser Ala Val Lys Thr Pro Asp Glu Leu Leu Arg 100 105 110 Gln Leu Arg Arg Val Val Arg Leu Leu Asn Gly Ser Val Asn Leu Asp 115 120 125 Ser Leu Ala Glu Gly Val Phe Arg Trp Cys Gln Glu Ser Asp Asp Leu 130 135 140 Leu Asn His His Arg Arg His Gln Arg Pro Thr Glu Phe Ile Arg Ile 145 150 155 160 Arg Trp Ala Leu Glu Tyr Tyr Gln Ala Gly Asp Val Asp Asn Glu Gln 165 170 175 Asn Gln * <210> 1336 <211> 521 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4479..6041) <400> 1336 Met Asn Ser Phe Ser Leu Leu Thr Thr Pro Trp Leu Pro Val Arg Phe 1 5 10 15 Lys Asp Gly Thr Thr Gly Lys Leu Ala Pro Val Asp Leu Ala Asp Glu 20 25 30 Asn Val Val Asp Ile Ala Ala Pro Arg Ala Asp Leu Gln Gly Ala Ala 35 40 45 Trp Gln Phe Leu Leu Gly Leu Leu Gln Ser Ser Phe Ala Pro Lys Asp 50 55 60 Tyr Arg Arg Trp Asp Asp Ile Trp Glu Asp Gly Leu Glu Ala Glu Lys 65 70 75 80 Leu Arg Glu Ala Leu Leu Ser Leu Glu His Pro Phe Gln Phe Gly Pro 85 90 95 Asp Ser Pro Ser Phe Met Gln Asp Phe Glu Val Leu Met Gly Asp Lys 100 105 110 Val Gln Val Ala Ser Leu Leu Pro Glu Ile Pro Gly Ala Gln Thr Thr 115 120 125 Lys Phe Asn Lys Asp His Phe Ile Lys Arg Gly Val Thr Glu His Val 130 135 140 Cys Ser His Cys Ser Ala Leu Ala Leu Phe Ser Leu Gln Leu Asn Ala 145 150 155 160 Pro Ser Gly Gly Lys Gly Tyr Arg Thr Gly Leu Arg Gly Gly Gly Pro 165 170 175 Met Thr Thr Leu Ile Glu Leu Gln Glu Tyr Gln Gly Asn Gln Gln Ala 180 185 190 Pro Leu Trp Arg Lys Leu Trp Leu Asn Val Met Pro Gln Asp Glu Ala 195 200 205 Asp Leu Pro Leu Pro Lys Lys Phe Asp Asp Leu Val Phe Pro Trp Leu 210 215 220 Gly Pro Thr Arg Thr Ser Glu Leu Ala Gly Ala Val Val Thr Asp Asp 225 230 235 240 Gln Val Asn Lys Leu Gln Ala Tyr Trp Gly Met Pro Arg Arg Ile Arg 245 250 255 Ile Asp Phe Asn Thr Thr Thr Val Gly Asn Cys Asp Ile Cys Gly Glu 260 265 270 Gln Ser Asp Ala Leu Leu Ser Leu Met Thr Thr Lys Asn Tyr Gly Ala 275 280 285 Asn Tyr Ala Met Trp Gln His Pro Leu Thr Pro Tyr Arg Val Pro Leu 290 295 300 Lys Glu Gly Gly Glu Phe Tyr Ser Val Lys Pro Gln Pro Gly Gly Leu 305 310 315 320 Ile Trp Arg Asp Trp Leu Gly Leu Ile Glu Thr Gly Lys Ser Glu Asn 325 330 335 Asn Thr Glu Leu Pro Ala Leu Val Val Lys Leu Phe Asn Ala Ser Ser 340 345 350 Leu Lys Gln Ala Lys Val Gly Leu Trp Gly Phe Gly Tyr Asp Phe Asp 355 360 365 Asn Met Lys Ala Arg Cys Trp Tyr Glu His His Phe Pro Leu Leu Leu 370 375 380 Asn Lys Lys Glu Gly Gln Ile Pro Lys Leu Arg Leu Ala Ala Gln Thr 385 390 395 400 Ala Ser Arg Ile Leu Ser Leu Leu Arg Ser Ala Leu Lys Glu Ala Trp 405 410 415 Phe Ser Asp Pro Lys Gly Ala Arg Gly Asp Phe Ser Phe Val Asp Ile 420 425 430 Asp Phe Trp Asn Lys Thr Gln His Arg Phe Leu Arg Leu Val Arg Gln 435 440 445 Ile Glu Glu Gly Gln Asp Ala Asp Glu Leu Leu Gly Lys Trp Gln Lys 450 455 460 Glu Ile Trp Leu Phe Ala Arg Gln Asp Phe Asp Glu Arg Val Phe Thr 465 470 475 480 Asn Pro Tyr Glu Pro Val Asp Leu Glu Arg Val Met Thr Ala Arg Lys 485 490 495 Lys Tyr Phe Thr Thr Ser Ala Glu Lys Gln Ser Ala Lys Ala Ala Arg 500 505 510 Glu Lys Lys Gln Glu Ala Ala Glu * 515 520 <210> 1337 <211> 886 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6139..8796) <400> 1337 Val Thr Phe Phe Asp Phe Trp Gly Lys Thr Arg Arg Gly Glu Lys Glu 1 5 10 15 Gly Gly Asp Gly Tyr His Leu Leu Cys Trp His Ser Leu Asp Val Ala 20 25 30 Ala Met Gly Tyr Leu Met Val Lys Arg Asn Cys Phe Gly Leu Ala Asp 35 40 45 Tyr Phe Arg Gln Leu Gly Ile Ser Asp Lys Glu Gln Ala Ala Gln Phe 50 55 60 Phe Ala Trp Leu Leu Cys Trp His Asp Ile Gly Lys Phe Ala Arg Ser 65 70 75 80 Phe Gln Gln Leu Tyr Leu Ala Pro Glu Leu Lys Ile Pro Glu Gly Ser 85 90 95 Arg Lys Asn Tyr Glu Lys Ile Ser His Ser Thr Leu Gly Tyr Trp Leu 100 105 110 Trp Asn Tyr Tyr Leu Ser Glu Cys Glu Glu Leu Leu Pro Ser Ser Ser 115 120 125 Leu Ser Ser Arg Lys Leu Thr Arg Val Ile Glu Met Trp Met Ser Ile 130 135 140 Thr Thr Gly His His Gly Arg Pro Pro Asp Arg Ile Asp Glu Leu Asp 145 150 155 160 Asn Phe Leu Pro Glu Asp Lys Ala Ala Ala Arg Asp Phe Leu Leu Glu 165 170 175 Ile Lys Ala Leu Phe Pro Leu Ile Glu Ile Pro Thr Phe Trp Asp Asp 180 185 190 Asp Glu Gly Val Glu Leu Leu Lys Gln Leu Ser Trp Tyr Ile Ser Ala 195 200 205 Thr Val Val Leu Ala Asp Trp Thr Gly Ser Ser Thr Arg Phe Phe Pro 210 215 220 Arg Val Ala His Pro Met Asp Ile Lys Asp Tyr Trp Gln Lys Thr Leu 225 230 235 240 Val Gln Ala Gln Asn Ala Leu Thr Val Phe Pro Pro Lys Ala Glu Thr 245 250 255 Ala Pro Phe Thr Gly Ile Asn Thr Leu Phe Pro Phe Ile Glu His Pro 260 265 270 Thr Pro Leu Gln Gln Lys Val Leu Asp Leu Asp Ile Ser Gln Pro Gly 275 280 285 Pro Gln Leu Phe Ile Leu Glu Asp Val Thr Gly Ala Gly Lys Thr Glu 290 295 300 Ala Ala Leu Ile Leu Ala His Arg Leu Met Ala Ala Arg Lys Ala Gln 305 310 315 320 Gly Leu Phe Phe Gly Leu Pro Thr Met Ala Thr Ala Asn Ala Met Tyr 325 330 335 Asp Arg Leu Val Lys Thr Trp Leu Ala Phe Tyr Ser Pro Glu Ser Arg 340 345 350 Pro Ser Leu Val Leu Ala His Ser Ala Arg Thr Leu Met Asp Arg Phe 355 360 365 Asn Glu Ser Leu Trp Ser Gly Asp Leu Val Gly Ser Glu Glu Pro Asp 370 375 380 Glu Gln Thr Phe Ser Gln Gly Cys Ala Ala Trp Phe Ala Asn Ser Asn 385 390 395 400 Lys Lys Ala Leu Leu Ala Glu Ile Gly Val Gly Thr Leu Asp Gln Ala 405 410 415 Met Met Ala Val Met Pro Phe Lys His Asn Asn Leu Arg Leu Leu Gly 420 425 430 Leu Ser Asn Lys Ile Leu Leu Ala Asp Glu Ile His Ala Cys Asp Ala 435 440 445 Tyr Met Ser Cys Ile Leu Glu Gly Leu Ile Glu Arg Gln Ala Arg Gly 450 455 460 Gly Asn Ser Val Ile Leu Leu Ser Ala Thr Leu Ser Gln Gln Gln Arg 465 470 475 480 Asp Lys Leu Val Ala Ala Phe Ala Arg Gly Thr Glu Gly Gln Gln Glu 485 490 495 Ala Pro Phe Leu Glu Lys Asp Asp Tyr Pro Trp Leu Thr His Val Thr 500 505 510 Lys Ser Asp Val Asn Ser His Arg Val Ala Thr Arg Lys Asp Val Glu 515 520 525 Arg Ser Val Ser Val Gly Trp Leu His Ser Glu Gln Glu Ser Ile Ala 530 535 540 Arg Ile Glu Ser Ala Val Ser Gln Gly Lys Cys Ile Ala Trp Ile Arg 545 550 555 560 Asn Ser Val Asp Asp Ala Ile Lys Val His Arg Gln Leu Leu Ala Arg 565 570 575 Gly Val Ile Pro Ala Ser Ser Leu Ser Leu Phe His Ser Arg Phe Ala 580 585 590 Phe Ser Asp Arg Gln Arg Ile Glu Met Glu Thr Leu Ala Arg Phe Gly 595 600 605 Lys Glu Asp Gly Ser Gln Arg Ala Gly Lys Val Leu Ile Cys Thr Gln 610 615 620 Val Leu Glu Gln Ser Val Asp Cys Asp Leu Asp Glu Met Ile Ser Asp 625 630 635 640 Leu Ala Pro Val Asp Leu Leu Ile Gln Arg Ala Gly Arg Leu Gln Arg 645 650 655 His Ile Arg Asp Ile Asn Gly Gln Leu Lys Arg Asp Gly Lys Asp Glu 660 665 670 Arg Ser Pro Pro Glu Leu Leu Ile Leu Ala Pro Val Trp Asp Asp Ala 675 680 685 Pro Gly Asp Glu Trp Phe Gly Ser Ala Met Arg Asn Ser Ala Tyr Val 690 695 700 Tyr Pro Asp His Gly Arg Ile Trp Leu Thr Gln Arg Val Leu Arg Glu 705 710 715 720 Gln Gly Ala Ile Gln Met Pro His Ala Ala Arg Leu Leu Ile Glu Ser 725 730 735 Val Tyr Gly Glu Asp Val Val Met Pro Glu Gly Phe Ala Arg Ser Glu 740 745 750 Gln Glu Gln Val Gly Lys Tyr Tyr Cys Asp Arg Ala Met Ala Lys Lys 755 760 765 Phe Val Leu Asn Phe Lys Pro Gly Tyr Ala Ala Asn Ile Asn Asp Tyr 770 775 780 Leu Pro Glu Lys Leu Ser Thr Arg Leu Ala Glu Glu Ser Val Ser Leu 785 790 795 800 Trp Leu Ala Thr Cys Ile Ala Gly Val Val Lys Pro Tyr Ala Thr Gly 805 810 815 Ala His Ala Trp Glu Met Ser Val Val Arg Val Arg Arg Ser Trp Trp 820 825 830 Lys Lys His Arg Asp Glu Phe Ser Leu Leu Glu Gly Glu Ala Phe Arg 835 840 845 Gln Trp Cys Ile Glu Gln Arg Gln Asp Pro Glu Met Ala Asn Val Ile 850 855 860 Leu Val Thr Asp Asp Glu Ser Cys Gly Tyr Ser Ala Arg Glu Gly Leu 865 870 875 880 Ile Gly Lys Val Asp * 885 <210> 1338 <211> 9057 <212> DNA <213> Escherichia coli O157:H7 <400> 1338 cgattgatca atataaagag gcccagcaat aaatagccag acctcccgtt aattatacgt 60 tatgcagcaa cgccttccgg tatcagcgaa gcaatttgct tacgccattg cgcttgctcc 120 tgttcgcctt ctgtacgttg accataaagt tgcgctatct gcgtaccatc atgggcaaac 180 aattccagac tggttacgta gccatcgctg gtcggtttac gggtaaccca ggcttcagca 240 atgctctctt ctaatagatg aagagtaaac gtcgggttga aaatattcag ccaacctttc 300 attggcacca ctttttctac cacaccggtg aaaatctgta cgcagccacg gttgccaaca 360 aacaccatga tttcattacc atcctgctgt gcagattcaa gaatttgcgc caacgcactg 420 ttggatactt tgcaggccaa atcgtctgcc accagattga acgcctgttg gcgcgtcagg 480 ttgtggcgct tgagcaacgt aaaaaactga tgaacgtcgg tcatcgcccg ccactcttgc 540 tcgaccacag tggcatcggc tcgcgtttga acaactggcg catcaacggc ttttaactca 600 agcggcgtat tctcatcggt gataaaccgt gccagaagct cactccatgc cgccatatcg 660 gtattgtcgg tggcataaac ttttagtaat gcatcgccct gatgatcaaa gaactgaata 720 ctctggcgtt cgccacgagc cgtgttttct ttgatgtgga aaacactggc ccattgattg 780 agaaacagac gtaaatccag cgcgcgcgga ttgaggatca atccggcatg tccgttcaaa 840 tgctggtttg tgaacgtacc aacttgctca tggactgcat attcattacg acaaatacat 900 ttggtttcgc caacactttc gagcgccgcc agaatttcac ggatatcgcc gtgcatccgc 960 cacgcatcgt gcgtgacgcg tgcaaatgcc agttctgctt ctctaatatt cattaaccct 1020 gcgatgtcac gcgcgtactt tccgggattt tgttctttta actcaagcca gcgtgtgtag 1080 tggttcattg tctctcttcc ttccagataa atgccccgaa atatcggggc agatgattac 1140 cattgataac tcacgaaaat ttttccgtta cgaccatcct gtgggatgcc ttgcggcgac 1200 cagtactctt tgtcgaaagc gttacccaac accaaagtag tggtcatacc tttgagcgcc 1260 tgttgtcctt gataactgac gtagaaatca ttcacgccat agcctggttg tttgctgtaa 1320 ctgctgctga tatgtgttga gcgatcggca aacgtaccaa cccacccaac agagaagcca 1380 ctgtgagcga tcggaatatt cagagtgctg gtaacagtat ccgggttaat gctggagatg 1440 tattcgccgg tatcggtgtc tttgccgcgg gtacggttat aggccacatc aaggctaaac 1500 agatcagtgg tatatttcgt catcacatcc cagccccaga ttttggcgtt cgggacgtta 1560 tacgacatag tcgtcgccgc cgcgaaatcg acggtcgtgg agatgtaatc cttcgctttg 1620 gtatcaaagt agctggcttt aaattccaga gcatcattgg acaacatcag gtcatcaaaa 1680 cgcagcccaa aaccgtactc ctgagtttcg ttagtttccg gacgtaagtt cgggtttggc 1740 acccaatagt tggtatagaa gcgaccaatc gagaagtgct tagaatcgtt atacatttcg 1800 cccatcgtcg gggcgcggaa tgcctgggca tatgagccaa ataacatcag ccagttagtc 1860 ggattgatag tcatccccgc acgagatgac catttgtcgg catcaacatc tttgtaaccg 1920 tcactgctac cgcgataact gtcatagcgg gttccgccaa gcagggtaat cggcagatcg 1980 cgtaaggtga tctcatcctg tagccagccg gagctaaaat cgatttttgc ttgcgggaag 2040 cccgtcgtcg cgccgcccgg atgttgttcc tgacgataat actcaccgcc atatgtcagt 2100 aagtgagaag cgaaactgtc ggcaaagaga gtggaacggt tctccagcct ggctcctttt 2160 gttatctgtt cacgatactc gccggaactc cccgtgtttt gcgcattaat acggacttcc 2220 gaccaataaa tttttgcatc tgcatttaac cagtcgttgc cctgcggggc gagtttataa 2280 gaaagctgcg catcgcgttg aattgttgaa cgatcaacca tcgggttgct gctttcagaa 2340 gccccaacgg tctgcggatt ttttggttca cgcgcgtcgt tgttgtagta acgcactaaa 2400 ccgctcagag actgggctga atcaatttgc caggtccctt tcgccagcat gttattaatg 2460 gactcgtcat tcggcgcggt ttcaccattg ctctggcgta aatcaccccg atcgcgactg 2520 gaccaggcca caataccatc cagattttca gttcgcccaa acgcgctcgc gcctaatccc 2580 aggctatggt cccccgtgcc gccagtacca aagacacgaa aaccactgct ttgtccttcc 2640 tgcaataaat cttttgcatc gaccgtatcg taggagatca ctccacccag cgcgccactg 2700 ccatacagta atgctgaagg tccacgaaca atctcaacac gcttgatcag cgccggatcg 2760 agaaaagtgc cattcaggtg tccggtatcc gttccctgac gaacaccatc gacaagaacc 2820 agcacgccgc gatgatcata gccacgcata tttacatcct gaccgttggt tcgtccggta 2880 ccatccagag taattccagg aacatgacgc agcagatcgg tggctgaagt agccgtttga 2940 ttttcaggag cggaagtgtc gatgacgctg accatcatag gcgcttcgaa ggaactacgg 3000 gcattccccg ttgccgtaac ggtcatggtt tcagtagcaa aagcaaacgt tggcaaggtg 3060 gcagaaacag ctaaggccaa taaactcaaa cgcaacgagg taaattgcgg acgtgacata 3120 gcgattctcc atgaggaaaa taaaaaatgc tggctgcctg ggttaatacc ggggtggctg 3180 gcgaaaaata aatttattta aaattcagag cgataatatt cgccgggtga gtttacaagc 3240 gtttatatcc catgaaattg cctgataact cggcaattac gcaaaagcac gccctctttg 3300 tcaggcaaaa cgatatgccc catcaggagt gaagagagct gtgcgttatc ccttgcaaat 3360 gctatggttt tgttatccat atggtcgtgt tttgttaaat gcaaacgtga taatgagaat 3420 tattatcgat caatttttta tgatcaagtt tttttttaac caccattaac acaataaaca 3480 gggggttatg aaacctatcc tgcgccctgt aaaccacctt gtttttatgg ttatcccccc 3540 atgcctcatc actaaatttt gtcgttaaca gtgataattt tttcttctct ttgctctgca 3600 agcctcgata tctctgggtt ctcagctttt tcccgcgatg aaatttagtc ggaaacaaga 3660 acgttagctg acgaagcatc ttgataaaaa tcaaaaataa atacgcttgt aacgccttgc 3720 gtattgaatc gacggttgta tttcatatat aactcaaatg ataatcatga tcattctcaa 3780 tttgataaga gttctcatat tatgccaagg atcatcacca ggccgtttct tttttcccca 3840 ctgacgttat gtatttcagc cgtggcctct gccgcgaaga ccgcagtaaa acgtaaaaaa 3900 ttgtttacgg cagtactggc tcttagctgg gcttttagcg taacggctgc cgaacgtatc 3960 gtggtcgcag gaggatcgct gacggagcta atctacgcga tgggcgctgg cgaacgcgtg 4020 gttggtgtcg atgaaacgac atcttatcca ccagaaaccg ccaaactgcc gcatattggc 4080 tactggaaac aactcagcag cgaaggcatt ttgtcacttc gcccggatag cgtaattacc 4140 tggcaggatg ccgggccaca aattgtgctc gaccaactac gagcgcagaa agtcaacgtc 4200 gtcaccctgc cgcgtgtgcc tgccaccctt cagcagatgt acgccaacat tcgccaactg 4260 gcaaaaacgc tacaggttcc tgaacaaggc gaggcgctgg tgacacaaat cagccaacgc 4320 ctggagcgag tacagcaaaa cgtggcgacc aaaaaagccc cggttaaagc catgtttatt 4380 ctctccgcag gcggaagtgc gccacaagtt gccggtaaag gcagcgtcgc ggacgccatt 4440 ctttcgcttg ccggagcaga aaacgtcgct acccaccagc agtacaaaag ctacagtgca 4500 gaatcactga ttgcggctaa tccagaagtg attgtcgtaa cctcacaaat ggtcgatggc 4560 gatattaatc ggctacgttc tattgctgga attacccaca ctgccgcatg gaaaaaccag 4620 cgcattatca ccgttgatca aaacctgatt ctgggaatgg gtccgcgtat tgctgatgtc 4680 gttgagtctt tacaccagca gctttggccg caataaatgg atttaaatca gacgaatgaa 4740 cgcaaataac accctggatc tcacgccaca ttttgcttta gacggtgatc agccatttaa 4800 agacaggcgc gccatgatgc cgtttcgtgg agccattccg gttgccaaag agcaactggc 4860 acagacctgg caagagatga tcaatcaaac ggcatcacct cgtaagcgac tggtttacct 4920 acacattcct ttttgtgcga cacactgcac gttttgtggt ttttatcaga accgttttaa 4980 tgaagatgcg tgtgctcatt ataccgacgc cctgattcgt gaaatagaaa tggaagcgga 5040 cagcgtattg catcagtctg cccccatcca cgcggtctat ttcggtggcg gtacgccttc 5100 cgcactttcg gcacacgatt tggccagaat catcaccaca ttacgagaaa agctgccact 5160 ggcccctgat tgtgaaatca ctatcgaagg acgggtattg aattttgacg ctgagcgaat 5220 cgatgcttgc cttgatgcag gagcaaaccg cttctcaatt ggtatccagt cgtttaacag 5280 caaaatccgc aagaaaatgg cccgcacctc ggatggccca accgctattg cgtttatgga 5340 aagcctggtc aaacgtgacc gtgctgcggt ggtctgtgac ctgctgtttg gcctgccggg 5400 tcaggatgcg caaacctggg gagaagatct ggctattgcc cgcgatatcg gtctcgacgg 5460 cgtcgatctc tatgcgctca atgtcctgtc caatacaccg ctgggcaagg ccgtggaaaa 5520 tgggcgtact accgtaccct caccggcaga acgtcgcgat ctttatctgc aaggatgtga 5580 ttttatggac gatgccggtt ggcgctgcat cagtaacagc cactggggcc gtaccacacg 5640 cgaacgcaat ctctataacc tgctgattaa acaaggtgcc gattgtctgg cctttggttc 5700 cggagccggc ggttcgatta atggttactc ctggatgaac gaacgcaatc ttcagacctg 5760 gcatgaatcc gtcgcggcag gcaaaaaacc gctgatgttg atcatgcgta acgccgaacg 5820 taatgcgcaa tggcgtcata ccttgcagtc aggtgttgaa acagcgcgcg taccgctgga 5880 tgaacttacg ccacatgccg aaaaactcgc gccgttactg gctcaatggc accaaaaagg 5940 cttaagtcgc gatgcttcaa cttgcctgcg gctgactaat gaaggtcgtt tctgggcaag 6000 caatattttg cagtctctta atgaactaat tcaggtactt aatgcgccag cgattatgcg 6060 tgaaaaacca taacaggagt gatttatgag ccatgtctcg ttacaagaat ttttgaaaac 6120 ggagccggac ggtacgctgg aggtggtagc cgaacaatac aacaccacac tgctggaggt 6180 agtgagaaat ctaccctcct ctaccgtagt gccaggcgat aaattcgata ctgtctggga 6240 taccgtctgc gaatggggca acgtcaccac gttagtacat actgccgatg taatcctcga 6300 atttagcggc gaactgcctt cgggtttcca tcgccacggc tatttcaacc tacgcggaaa 6360 gcacggcatg tccgggcata tcaaagcaga aaactgcacg catattgcct taatcgaacg 6420 taaatttatg ggcatggaca ccgcgtccat tctctttttc aacaaagaag gcagcgccat 6480 gctgaaaatc ttcctcggca gggatgacca tcgtcagctc ctgagcgaac aagtcagcgc 6540 cttccatact ctggcggcat cgttaaagga acacgcctga tgacgccgtg gctactcttt 6600 ggcgcaggcg gaaaaggtgt gggtgccaga acgcttgaac tggcgctggc ggaacaacgt 6660 ccggtcgttg ctgtcattcg tcatgccgat gccgccacga aactggcgca acaaggcgta 6720 caggttttta caggcgacgc ctgtgatgcc agcgtagtcg cggctgcttg ccgcgcagct 6780 ggcccggatg cgcttatcat ctcaacaatg ggaggagctc aggattatct ggcgcacaga 6840 acagtgattg atgaggccga aaaggccggc atcagtcgca tgattctggt gacctctttg 6900 ggatgcggcg atagctggcc gtttttatcg gagcgggcaa aggctgcgtt tggtcaggcg 6960 gtacgggaaa aaacgctggc ggaaagctgg ctgcaaacca gccagctaga ctacgccatt 7020 ctccgccctg gtggtctgct tgacggcgca gcaacaggca aagcacaacg gatacaaaat 7080 caggagtgtc atggttttgt ccgccgtgcc gatgtcgccg cacatatcca tgaactggca 7140 aatgcgccag cacttaacca gcaggtctac agtctgattg aaccggacct gaaaccggcg 7200 tgataccccg gcgcggcatg tccgcgccgt aatgtcgtaa cggagttttg cgtgctcaag 7260 gattcatttt catccgccag ggtctttatg ggactatcac tattattgct tgccctggtg 7320 ctgttcggtg ctagtcaggg agcgttaaag atcagttttg atgccctttt tgatgaggaa 7380 taccgcgata tctggctcaa tattcgtcta ccacgggttt tgctggcggt gctggtaggt 7440 gcagcgttgg caaccgcagg ggtaattatg caggggcttt ttcgcaaccc aatggctgac 7500 ccaggattac tcggcgtcag tagcggttct gcattaatgg ttggcgttgc aattgtgctg 7560 cccttctcct tcccagtggt gctggtgctc tatgagcaaa tggtgtttgc cattgccgga 7620 agtttagtag tctgcgccat catttttctc atcacgcagc gccatcgcga tggcagcatg 7680 atgcaattat tactcgccgg tatcgccatc aatgccctgt gcggcgcagc gatcggcatc 7740 ctgagctata ttggcgatga gcagcagcta cgacaactca cattgtggat gatgggcaat 7800 cttggacagg cgcaatggcc gacgttattg gttgccagtt cattcatcct tccggccatt 7860 atcgcaacaa cttgtctcgc cggaacgctg aatttactgc agctcggtga tgaagaagcc 7920 cattacctcg gcgtgaacgt taagcgtaaa cgccagcaat tactattagt gagctcactg 7980 ctcgttggtg ctgccgtatc ggtaagcggc attatcggct ttattggcct ggtgatcccg 8040 catctgattc gcatgactac cggagcaaat caccgctggc tcatcccttg ttccgccctc 8100 gccggagcct gtttattgct gatggcagac acgcttgccc gcacgctggt acagccagca 8160 gaaatgcccg tgggattatt aaccagcctg cttggtggcc cttattttat gtggttgatt 8220 ctgcgaaatc ggaggatcac atgatcagcg cccagaatct ggtttatagc cttcaggggc 8280 ggcgtctgac tgataatgtc tcgctgactt ttcccggtgg ggaaattgtt gccattctcg 8340 gccctaatgg tgcgggaaaa tctacgctgc ttcgccagtt aaccggctat cttcaacctg 8400 atagcggcga atgtcggttg tttaataagc cattaaatga atggtcgatt actgaactgg 8460 cgaaacaccg ggccgtgatg cgtcaaaata gccacatggc gtttccattc agcgtacaag 8520 aagttatcca gatgggtcgg catccgcatc gtactggtaa tcaggataat gaaacagcac 8580 aaataatggc gttatgtgac tgtcaggcgt tagcaaaccg cgactatcgg caattatccg 8640 gtggtgaaca acagcgcgtg caattagcgc gcctgctggt gcaactctgg gaaccaactc 8700 cctcaccgaa atggttattt cttgatgaac caacttcggc gctggatatt caccatcagc 8760 agcacttgtt tcgtttatta cgccagttag ttcacgagcg gcagttcaat gtctgctgca 8820 tattgcacga tctaaatctt gccgcgcatt atgcagaccg tgttgtatta atgcaaaaag 8880 gaaaggttat cgcaaatggt aaaccacagg acgtattgac acagcaggcg ctgacaatgc 8940 tctacggcgc ggatattacc gtacttaaag atcctgccaa ccattcacca ctgatcgtcc 9000 tcgatcatta aaagcaacag gagtaccgca ctggtactcc tgcgaataaa taactat 9057 <210> 1339 <211> 343 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(60..1088) <400> 1339 Met Asn His Tyr Thr Arg Trp Leu Glu Leu Lys Glu Gln Asn Pro Gly 1 5 10 15 Lys Tyr Ala Arg Asp Ile Ala Gly Leu Met Asn Ile Arg Glu Ala Glu 20 25 30 Leu Ala Phe Ala Arg Val Thr His Asp Ala Trp Arg Met His Gly Asp 35 40 45 Ile Arg Glu Ile Leu Ala Ala Leu Glu Ser Val Gly Glu Thr Lys Cys 50 55 60 Ile Cys Arg Asn Glu Tyr Ala Val His Glu Gln Val Gly Thr Phe Thr 65 70 75 80 Asn Gln His Leu Asn Gly His Ala Gly Leu Ile Leu Asn Pro Arg Ala 85 90 95 Leu Asp Leu Arg Leu Phe Leu Asn Gln Trp Ala Ser Val Phe His Ile 100 105 110 Lys Glu Asn Thr Ala Arg Gly Glu Arg Gln Ser Ile Gln Phe Phe Asp 115 120 125 His Gln Gly Asp Ala Leu Leu Lys Val Tyr Ala Thr Asp Asn Thr Asp 130 135 140 Met Ala Ala Trp Ser Glu Leu Leu Ala Arg Phe Ile Thr Asp Glu Asn 145 150 155 160 Thr Pro Leu Glu Leu Lys Ala Val Asp Ala Pro Val Val Gln Thr Arg 165 170 175 Ala Asp Ala Thr Val Val Glu Gln Glu Trp Arg Ala Met Thr Asp Val 180 185 190 His Gln Phe Phe Thr Leu Leu Lys Arg His Asn Leu Thr Arg Gln Gln 195 200 205 Ala Phe Asn Leu Val Ala Asp Asp Leu Ala Cys Lys Val Ser Asn Ser 210 215 220 Ala Leu Ala Gln Ile Leu Glu Ser Ala Gln Gln Asp Gly Asn Glu Ile 225 230 235 240 Met Val Phe Val Gly Asn Arg Gly Cys Val Gln Ile Phe Thr Gly Val 245 250 255 Val Glu Lys Val Val Pro Met Lys Gly Trp Leu Asn Ile Phe Asn Pro 260 265 270 Thr Phe Thr Leu His Leu Leu Glu Glu Ser Ile Ala Glu Ala Trp Val 275 280 285 Thr Arg Lys Pro Thr Ser Asp Gly Tyr Val Thr Ser Leu Glu Leu Phe 290 295 300 Ala His Asp Gly Thr Gln Ile Ala Gln Leu Tyr Gly Gln Arg Thr Glu 305 310 315 320 Gly Glu Gln Glu Gln Ala Gln Trp Arg Lys Gln Ile Ala Ser Leu Ile 325 330 335 Pro Glu Gly Val Ala Ala * 340 <210> 1340 <211> 661 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1137..3119) <400> 1340 Met Ser Arg Pro Gln Phe Thr Ser Leu Arg Leu Ser Leu Leu Ala Leu 1 5 10 15 Ala Val Ser Ala Thr Leu Pro Thr Phe Ala Phe Ala Thr Glu Thr Met 20 25 30 Thr Val Thr Ala Thr Gly Asn Ala Arg Ser Ser Phe Glu Ala Pro Met 35 40 45 Met Val Ser Val Ile Asp Thr Ser Ala Pro Glu Asn Gln Thr Ala Thr 50 55 60 Ser Ala Thr Asp Leu Leu Arg His Val Pro Gly Ile Thr Leu Asp Gly 65 70 75 80 Thr Gly Arg Thr Asn Gly Gln Asp Val Asn Met Arg Gly Tyr Asp His 85 90 95 Arg Gly Val Leu Val Leu Val Asp Gly Val Arg Gln Gly Thr Asp Thr 100 105 110 Gly His Leu Asn Gly Thr Phe Leu Asp Pro Ala Leu Ile Lys Arg Val 115 120 125 Glu Ile Val Arg Gly Pro Ser Ala Leu Leu Tyr Gly Ser Gly Ala Leu 130 135 140 Gly Gly Val Ile Ser Tyr Asp Thr Val Asp Ala Lys Asp Leu Leu Gln 145 150 155 160 Glu Gly Gln Ser Ser Gly Phe Arg Val Phe Gly Thr Gly Gly Thr Gly 165 170 175 Asp His Ser Leu Gly Leu Gly Ala Ser Ala Phe Gly Arg Thr Glu Asn 180 185 190 Leu Asp Gly Ile Val Ala Trp Ser Ser Arg Asp Arg Gly Asp Leu Arg 195 200 205 Gln Ser Asn Gly Glu Thr Ala Pro Asn Asp Glu Ser Ile Asn Asn Met 210 215 220 Leu Ala Lys Gly Thr Trp Gln Ile Asp Ser Ala Gln Ser Leu Ser Gly 225 230 235 240 Leu Val Arg Tyr Tyr Asn Asn Asp Ala Arg Glu Pro Lys Asn Pro Gln 245 250 255 Thr Val Gly Ala Ser Glu Ser Ser Asn Pro Met Val Asp Arg Ser Thr 260 265 270 Ile Gln Arg Asp Ala Gln Leu Ser Tyr Lys Leu Ala Pro Gln Gly Asn 275 280 285 Asp Trp Leu Asn Ala Asp Ala Lys Ile Tyr Trp Ser Glu Val Arg Ile 290 295 300 Asn Ala Gln Asn Thr Gly Ser Ser Gly Glu Tyr Arg Glu Gln Ile Thr 305 310 315 320 Lys Gly Ala Arg Leu Glu Asn Arg Ser Thr Leu Phe Ala Asp Ser Phe 325 330 335 Ala Ser His Leu Leu Thr Tyr Gly Gly Glu Tyr Tyr Arg Gln Glu Gln 340 345 350 His Pro Gly Gly Ala Thr Thr Gly Phe Pro Gln Ala Lys Ile Asp Phe 355 360 365 Ser Ser Gly Trp Leu Gln Asp Glu Ile Thr Leu Arg Asp Leu Pro Ile 370 375 380 Thr Leu Leu Gly Gly Thr Arg Tyr Asp Ser Tyr Arg Gly Ser Ser Asp 385 390 395 400 Gly Tyr Lys Asp Val Asp Ala Asp Lys Trp Ser Ser Arg Ala Gly Met 405 410 415 Thr Ile Asn Pro Thr Asn Trp Leu Met Leu Phe Gly Ser Tyr Ala Gln 420 425 430 Ala Phe Arg Ala Pro Thr Met Gly Glu Met Tyr Asn Asp Ser Lys His 435 440 445 Phe Ser Ile Gly Arg Phe Tyr Thr Asn Tyr Trp Val Pro Asn Pro Asn 450 455 460 Leu Arg Pro Glu Thr Asn Glu Thr Gln Glu Tyr Gly Phe Gly Leu Arg 465 470 475 480 Phe Asp Asp Leu Met Leu Ser Asn Asp Ala Leu Glu Phe Lys Ala Ser 485 490 495 Tyr Phe Asp Thr Lys Ala Lys Asp Tyr Ile Ser Thr Thr Val Asp Phe 500 505 510 Ala Ala Ala Thr Thr Met Ser Tyr Asn Val Pro Asn Ala Lys Ile Trp 515 520 525 Gly Trp Asp Val Met Thr Lys Tyr Thr Thr Asp Leu Phe Ser Leu Asp 530 535 540 Val Ala Tyr Asn Arg Thr Arg Gly Lys Asp Thr Asp Thr Gly Glu Tyr 545 550 555 560 Ile Ser Ser Ile Asn Pro Asp Thr Val Thr Ser Thr Leu Asn Ile Pro 565 570 575 Ile Ala His Ser Gly Phe Ser Val Gly Trp Val Gly Thr Phe Ala Asp 580 585 590 Arg Ser Thr His Ile Ser Ser Ser Tyr Ser Lys Gln Pro Gly Tyr Gly 595 600 605 Val Asn Asp Phe Tyr Val Ser Tyr Gln Gly Gln Gln Ala Leu Lys Gly 610 615 620 Met Thr Thr Thr Leu Val Leu Gly Asn Ala Phe Asp Lys Glu Tyr Trp 625 630 635 640 Ser Pro Gln Gly Ile Pro Gln Asp Gly Arg Asn Gly Lys Ile Phe Val 645 650 655 Ser Tyr Gln Trp * 660 <210> 1341 <211> 69 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3395..3601) <400> 1341 Leu Gln Ser Lys Glu Lys Lys Lys Leu Ser Leu Leu Thr Thr Lys Phe 1 5 10 15 Ser Asp Glu Ala Trp Gly Asp Asn His Lys Asn Lys Val Val Tyr Arg 20 25 30 Ala Gln Asp Arg Phe His Asn Pro Leu Phe Ile Val Leu Met Val Val 35 40 45 Lys Lys Lys Leu Asp His Lys Lys Leu Ile Asp Asn Asn Ser His Tyr 50 55 60 His Val Cys Ile * 65 <210> 1342 <211> 305 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3802..4716) <400> 1342 Met Pro Arg Ile Ile Thr Arg Pro Phe Leu Phe Ser Pro Leu Thr Leu 1 5 10 15 Cys Ile Ser Ala Val Ala Ser Ala Ala Lys Thr Ala Val Lys Arg Lys 20 25 30 Lys Leu Phe Thr Ala Val Leu Ala Leu Ser Trp Ala Phe Ser Val Thr 35 40 45 Ala Ala Glu Arg Ile Val Val Ala Gly Gly Ser Leu Thr Glu Leu Ile 50 55 60 Tyr Ala Met Gly Ala Gly Glu Arg Val Val Gly Val Asp Glu Thr Thr 65 70 75 80 Ser Tyr Pro Pro Glu Thr Ala Lys Leu Pro His Ile Gly Tyr Trp Lys 85 90 95 Gln Leu Ser Ser Glu Gly Ile Leu Ser Leu Arg Pro Asp Ser Val Ile 100 105 110 Thr Trp Gln Asp Ala Gly Pro Gln Ile Val Leu Asp Gln Leu Arg Ala 115 120 125 Gln Lys Val Asn Val Val Thr Leu Pro Arg Val Pro Ala Thr Leu Gln 130 135 140 Gln Met Tyr Ala Asn Ile Arg Gln Leu Ala Lys Thr Leu Gln Val Pro 145 150 155 160 Glu Gln Gly Glu Ala Leu Val Thr Gln Ile Ser Gln Arg Leu Glu Arg 165 170 175 Val Gln Gln Asn Val Ala Thr Lys Lys Ala Pro Val Lys Ala Met Phe 180 185 190 Ile Leu Ser Ala Gly Gly Ser Ala Pro Gln Val Ala Gly Lys Gly Ser 195 200 205 Val Ala Asp Ala Ile Leu Ser Leu Ala Gly Ala Glu Asn Val Ala Thr 210 215 220 His Gln Gln Tyr Lys Ser Tyr Ser Ala Glu Ser Leu Ile Ala Ala Asn 225 230 235 240 Pro Glu Val Ile Val Val Thr Ser Gln Met Val Asp Gly Asp Ile Asn 245 250 255 Arg Leu Arg Ser Ile Ala Gly Ile Thr His Thr Ala Ala Trp Lys Asn 260 265 270 Gln Arg Ile Ile Thr Val Asp Gln Asn Leu Ile Leu Gly Met Gly Pro 275 280 285 Arg Ile Ala Asp Val Val Glu Ser Leu His Gln Gln Leu Trp Pro Gln 290 295 300 * <210> 1343 <211> 446 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4736..6073) <400> 1343 Met Asn Ala Asn Asn Thr Leu Asp Leu Thr Pro His Phe Ala Leu Asp 1 5 10 15 Gly Asp Gln Pro Phe Lys Asp Arg Arg Ala Met Met Pro Phe Arg Gly 20 25 30 Ala Ile Pro Val Ala Lys Glu Gln Leu Ala Gln Thr Trp Gln Glu Met 35 40 45 Ile Asn Gln Thr Ala Ser Pro Arg Lys Arg Leu Val Tyr Leu His Ile 50 55 60 Pro Phe Cys Ala Thr His Cys Thr Phe Cys Gly Phe Tyr Gln Asn Arg 65 70 75 80 Phe Asn Glu Asp Ala Cys Ala His Tyr Thr Asp Ala Leu Ile Arg Glu 85 90 95 Ile Glu Met Glu Ala Asp Ser Val Leu His Gln Ser Ala Pro Ile His 100 105 110 Ala Val Tyr Phe Gly Gly Gly Thr Pro Ser Ala Leu Ser Ala His Asp 115 120 125 Leu Ala Arg Ile Ile Thr Thr Leu Arg Glu Lys Leu Pro Leu Ala Pro 130 135 140 Asp Cys Glu Ile Thr Ile Glu Gly Arg Val Leu Asn Phe Asp Ala Glu 145 150 155 160 Arg Ile Asp Ala Cys Leu Asp Ala Gly Ala Asn Arg Phe Ser Ile Gly 165 170 175 Ile Gln Ser Phe Asn Ser Lys Ile Arg Lys Lys Met Ala Arg Thr Ser 180 185 190 Asp Gly Pro Thr Ala Ile Ala Phe Met Glu Ser Leu Val Lys Arg Asp 195 200 205 Arg Ala Ala Val Val Cys Asp Leu Leu Phe Gly Leu Pro Gly Gln Asp 210 215 220 Ala Gln Thr Trp Gly Glu Asp Leu Ala Ile Ala Arg Asp Ile Gly Leu 225 230 235 240 Asp Gly Val Asp Leu Tyr Ala Leu Asn Val Leu Ser Asn Thr Pro Leu 245 250 255 Gly Lys Ala Val Glu Asn Gly Arg Thr Thr Val Pro Ser Pro Ala Glu 260 265 270 Arg Arg Asp Leu Tyr Leu Gln Gly Cys Asp Phe Met Asp Asp Ala Gly 275 280 285 Trp Arg Cys Ile Ser Asn Ser His Trp Gly Arg Thr Thr Arg Glu Arg 290 295 300 Asn Leu Tyr Asn Leu Leu Ile Lys Gln Gly Ala Asp Cys Leu Ala Phe 305 310 315 320 Gly Ser Gly Ala Gly Gly Ser Ile Asn Gly Tyr Ser Trp Met Asn Glu 325 330 335 Arg Asn Leu Gln Thr Trp His Glu Ser Val Ala Ala Gly Lys Lys Pro 340 345 350 Leu Met Leu Ile Met Arg Asn Ala Glu Arg Asn Ala Gln Trp Arg His 355 360 365 Thr Leu Gln Ser Gly Val Glu Thr Ala Arg Val Pro Leu Asp Glu Leu 370 375 380 Thr Pro His Ala Glu Lys Leu Ala Pro Leu Leu Ala Gln Trp His Gln 385 390 395 400 Lys Gly Leu Ser Arg Asp Ala Ser Thr Cys Leu Arg Leu Thr Asn Glu 405 410 415 Gly Arg Phe Trp Ala Ser Asn Ile Leu Gln Ser Leu Asn Glu Leu Ile 420 425 430 Gln Val Leu Asn Ala Pro Ala Ile Met Arg Glu Lys Pro * 435 440 445 <210> 1344 <211> 165 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6086..6580) <400> 1344 Met Ser His Val Ser Leu Gln Glu Phe Leu Lys Thr Glu Pro Asp Gly 1 5 10 15 Thr Leu Glu Val Val Ala Glu Gln Tyr Asn Thr Thr Leu Leu Glu Val 20 25 30 Val Arg Asn Leu Pro Ser Ser Thr Val Val Pro Gly Asp Lys Phe Asp 35 40 45 Thr Val Trp Asp Thr Val Cys Glu Trp Gly Asn Val Thr Thr Leu Val 50 55 60 His Thr Ala Asp Val Ile Leu Glu Phe Ser Gly Glu Leu Pro Ser Gly 65 70 75 80 Phe His Arg His Gly Tyr Phe Asn Leu Arg Gly Lys His Gly Met Ser 85 90 95 Gly His Ile Lys Ala Glu Asn Cys Thr His Ile Ala Leu Ile Glu Arg 100 105 110 Lys Phe Met Gly Met Asp Thr Ala Ser Ile Leu Phe Phe Asn Lys Glu 115 120 125 Gly Ser Ala Met Leu Lys Ile Phe Leu Gly Arg Asp Asp His Arg Gln 130 135 140 Leu Leu Ser Glu Gln Val Ser Ala Phe His Thr Leu Ala Ala Ser Leu 145 150 155 160 Lys Glu His Ala * <210> 1345 <211> 208 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6580..7203) <400> 1345 Met Thr Pro Trp Leu Leu Phe Gly Ala Gly Gly Lys Gly Val Gly Ala 1 5 10 15 Arg Thr Leu Glu Leu Ala Leu Ala Glu Gln Arg Pro Val Val Ala Val 20 25 30 Ile Arg His Ala Asp Ala Ala Thr Lys Leu Ala Gln Gln Gly Val Gln 35 40 45 Val Phe Thr Gly Asp Ala Cys Asp Ala Ser Val Val Ala Ala Ala Cys 50 55 60 Arg Ala Ala Gly Pro Asp Ala Leu Ile Ile Ser Thr Met Gly Gly Ala 65 70 75 80 Gln Asp Tyr Leu Ala His Arg Thr Val Ile Asp Glu Ala Glu Lys Ala 85 90 95 Gly Ile Ser Arg Met Ile Leu Val Thr Ser Leu Gly Cys Gly Asp Ser 100 105 110 Trp Pro Phe Leu Ser Glu Arg Ala Lys Ala Ala Phe Gly Gln Ala Val 115 120 125 Arg Glu Lys Thr Leu Ala Glu Ser Trp Leu Gln Thr Ser Gln Leu Asp 130 135 140 Tyr Ala Ile Leu Arg Pro Gly Gly Leu Leu Asp Gly Ala Ala Thr Gly 145 150 155 160 Lys Ala Gln Arg Ile Gln Asn Gln Glu Cys His Gly Phe Val Arg Arg 165 170 175 Ala Asp Val Ala Ala His Ile His Glu Leu Ala Asn Ala Pro Ala Leu 180 185 190 Asn Gln Gln Val Tyr Ser Leu Ile Glu Pro Asp Leu Lys Pro Ala * 195 200 205 <210> 1346 <211> 319 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7288..8244) <400> 1346 Met Gly Leu Ser Leu Leu Leu Leu Ala Leu Val Leu Phe Gly Ala Ser 1 5 10 15 Gln Gly Ala Leu Lys Ile Ser Phe Asp Ala Leu Phe Asp Glu Glu Tyr 20 25 30 Arg Asp Ile Trp Leu Asn Ile Arg Leu Pro Arg Val Leu Leu Ala Val 35 40 45 Leu Val Gly Ala Ala Leu Ala Thr Ala Gly Val Ile Met Gln Gly Leu 50 55 60 Phe Arg Asn Pro Met Ala Asp Pro Gly Leu Leu Gly Val Ser Ser Gly 65 70 75 80 Ser Ala Leu Met Val Gly Val Ala Ile Val Leu Pro Phe Ser Phe Pro 85 90 95 Val Val Leu Val Leu Tyr Glu Gln Met Val Phe Ala Ile Ala Gly Ser 100 105 110 Leu Val Val Cys Ala Ile Ile Phe Leu Ile Thr Gln Arg His Arg Asp 115 120 125 Gly Ser Met Met Gln Leu Leu Leu Ala Gly Ile Ala Ile Asn Ala Leu 130 135 140 Cys Gly Ala Ala Ile Gly Ile Leu Ser Tyr Ile Gly Asp Glu Gln Gln 145 150 155 160 Leu Arg Gln Leu Thr Leu Trp Met Met Gly Asn Leu Gly Gln Ala Gln 165 170 175 Trp Pro Thr Leu Leu Val Ala Ser Ser Phe Ile Leu Pro Ala Ile Ile 180 185 190 Ala Thr Thr Cys Leu Ala Gly Thr Leu Asn Leu Leu Gln Leu Gly Asp 195 200 205 Glu Glu Ala His Tyr Leu Gly Val Asn Val Lys Arg Lys Arg Gln Gln 210 215 220 Leu Leu Leu Val Ser Ser Leu Leu Val Gly Ala Ala Val Ser Val Ser 225 230 235 240 Gly Ile Ile Gly Phe Ile Gly Leu Val Ile Pro His Leu Ile Arg Met 245 250 255 Thr Thr Gly Ala Asn His Arg Trp Leu Ile Pro Cys Ser Ala Leu Ala 260 265 270 Gly Ala Cys Leu Leu Leu Met Ala Asp Thr Leu Ala Arg Thr Leu Val 275 280 285 Gln Pro Ala Glu Met Pro Val Gly Leu Leu Thr Ser Leu Leu Gly Gly 290 295 300 Pro Tyr Phe Met Trp Leu Ile Leu Arg Asn Arg Arg Ile Thr * 305 310 315 <210> 1347 <211> 257 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8241..9011) <400> 1347 Met Ile Ser Ala Gln Asn Leu Val Tyr Ser Leu Gln Gly Arg Arg Leu 1 5 10 15 Thr Asp Asn Val Ser Leu Thr Phe Pro Gly Gly Glu Ile Val Ala Ile 20 25 30 Leu Gly Pro Asn Gly Ala Gly Lys Ser Thr Leu Leu Arg Gln Leu Thr 35 40 45 Gly Tyr Leu Gln Pro Asp Ser Gly Glu Cys Arg Leu Phe Asn Lys Pro 50 55 60 Leu Asn Glu Trp Ser Ile Thr Glu Leu Ala Lys His Arg Ala Val Met 65 70 75 80 Arg Gln Asn Ser His Met Ala Phe Pro Phe Ser Val Gln Glu Val Ile 85 90 95 Gln Met Gly Arg His Pro His Arg Thr Gly Asn Gln Asp Asn Glu Thr 100 105 110 Ala Gln Ile Met Ala Leu Cys Asp Cys Gln Ala Leu Ala Asn Arg Asp 115 120 125 Tyr Arg Gln Leu Ser Gly Gly Glu Gln Gln Arg Val Gln Leu Ala Arg 130 135 140 Leu Leu Val Gln Leu Trp Glu Pro Thr Pro Ser Pro Lys Trp Leu Phe 145 150 155 160 Leu Asp Glu Pro Thr Ser Ala Leu Asp Ile His His Gln Gln His Leu 165 170 175 Phe Arg Leu Leu Arg Gln Leu Val His Glu Arg Gln Phe Asn Val Cys 180 185 190 Cys Ile Leu His Asp Leu Asn Leu Ala Ala His Tyr Ala Asp Arg Val 195 200 205 Val Leu Met Gln Lys Gly Lys Val Ile Ala Asn Gly Lys Pro Gln Asp 210 215 220 Val Leu Thr Gln Gln Ala Leu Thr Met Leu Tyr Gly Ala Asp Ile Thr 225 230 235 240 Val Leu Lys Asp Pro Ala Asn His Ser Pro Leu Ile Val Leu Asp His 245 250 255 * <210> 1348 <211> 8951 <212> DNA <213> Escherichia coli O157:H7 <400> 1348 gtgacaaact tgcatctgga gttgtgaaag ctgtttataa ttccgcaaca gcaggctggg 60 aagaatcaat cgcggtccag gggagcatcg gtggatttga ttatcgcatc aacggtagtt 120 attctgatca gggcaatcgt gatacgccgg atggacgtct gccgaatacc aactatcgta 180 acaatagtca gggtgtatgg ttgggttata actccggaaa ccatcgtttt ggcctctcgc 240 ttgatcgcta cagactcgcg acacaaactt actatgagga tccagacgga agttatgagg 300 catttagtgt caaaatacct aaacttgaac gagagaaagt tggggtattc tatgacacag 360 acgtggacgg tgactatcta aaaaaaattc atttcgacgc gtatgagcag accatccagc 420 gccaatttgc caacgaagta aaaacgacac agcctgttcc cagtccgatg attcaggctc 480 tgaccgttca taacaagact gacacccatg ataagcaata cactcaggcg gtcacattgc 540 agagtcactt ttcgctgcct gctaataatg aacttgttac cggtgcacag tacaaacaag 600 atagggtcag ccaaaggtcc ggtggcatga cctcaagcaa atctctgacc ggcttcatta 660 ataaggaaac acgaactcgc tcctattatg agtcagagca aagtacagtc tcactattcg 720 cacaaaatga ctggcaattc gccgatcact ggacatggac aatgggagtt cgccaatact 780 ggctttcttc aaagttgacg cgtggtgacg gagtatcata taccgcaggc attataagcg 840 atacctctct tgccagagag tctgcgagtg atcacgaaat ggtaacatct acaagcctgc 900 gctattcagg tttcgataac ctggagttac gcgctgcgtt cgcgcaaggc tacgtatttc 960 ccacactctc ccagcttttt atgcagacat ctgcgggcgg cagtgtcaca tacggaaatc 1020 ctgatcttaa ggctgaacac tccaataact ttgaattagg tgcacgatat aatggtaatc 1080 agtggctgat tgacagcgca gtttactact cagaagctaa agattatatt gcaagtctga 1140 tctgtgatgg cagtatagtt tgcaatggta acaccaactc ctcccgtagt agctactatt 1200 attatgacaa tattgatcgg gcaaaaacat ggggactgga aataagcgcg gaatataatg 1260 gctgggtttt ctcgccatat atcagtggca atttaattcg tcggcaatat gaaacttcaa 1320 cattaaaaac aactaataca ggtgaaccag cgataaacgg acgtataggg ctgaaacata 1380 ctcttgtgat gggtcaggcc aacataatct ctgatgtttt tattcgtgct gcctctagtg 1440 caaaagatga cagtaacggt accgaaacaa atgttccggg ctgggccact ctcaactttg 1500 cagtaaatac agaattcggt aacgaggatc agtaccggat taacctggca ctcaataacc 1560 tgacagacaa acgctaccgt acagcacatg aaactattcc tgcagcaggt tttaatgcag 1620 ctataggttt tgtatggaat ttctgatgac aaaaacaatc gttatggaat tctttgtcct 1680 gatctgcccg ctttgcgggc aggctaacga acgtattgtg tttgttgaag gtttttcgac 1740 gttgttttcc atctgtgggt gaatatttat tcttcccgcc agcatgactc tatactcatt 1800 gctacgacaa tgacttataa agctggttac tgaacctata cctttgtaat tcaaaagtga 1860 tatcagttca caacgcaata ctatttttag attatttact ctcacccaga tactgaatca 1920 atggataata ccttttgatt tatcccgacg cggaagaagg tggtgaaccg ccccggaaat 1980 cctggagact aaactccctg agaaagaggt aaacaggatg actaaaaata cacgtttttc 2040 ccccgaggtc cgtcaacggg cagttcgtat ggttctggaa agtcagggcg aatatgactc 2100 acaatgggcg gcaatttgtt ccattgcccc aaagattggc tgtacaccag agactctgcg 2160 tgtgtgggtt cgtcagcatg agcgggatac cgggagtggt gatggtggac tcaccaccgc 2220 tgaacgtcag cgtctgaaag agctggaacg tgaaaatcgt gaactgcgcc gcagtaacga 2280 tatccttcgc caggcttccg cttattttgc gaaggcggag ttcgaccgcc tctggaaaaa 2340 atgatgccac tgctggataa gctgcgtgag cagtacgggg tcggaccggt atgcagcgaa 2400 ctgcatattg ccccgtcaac gtattaccat tgtcagcaac agcgacatca tccggataaa 2460 cgcagtgccc atgcgcagca cgatgactgg ctgaagaaag agatacagcg cgtatacgat 2520 gaaaatcatc aggtgtacgg tgtgcgtaaa gtctggcgcc agttgttacg cgaaggtatc 2580 agggtggcca gatgcactgt ggcacgtctc atggcggtta tgggacttgc cggtgttctc 2640 cggggtaaaa aggtccgcac taccgtcagc cggaaagccg tttccgcagg cgaccgcgta 2700 aaccgtcagt tcgtggcaga acgtcctgac cagctgtggg tggctgattt tacttacgtc 2760 agcacatggc agggcttcgt ctatgtggcg ttcatcattg atgtgtttgc cggatgtatc 2820 gtggggtggc gagtctcatc gtctatggaa acgacattcg tgctggatgc actggagcag 2880 gcgttgtggg cccgtcggcc gtccggcaca atccatcaca gtgataaagg ttctcagtat 2940 gtatcgctgg cctacacgca gcggcttaag gaagccggat tactggcatc aacagggagt 3000 actggcgact cgtatgacaa cgcgatggct gagagcatca atggtcttta caaagcggag 3060 gtaatacacc gtaagagctg gaaaaaccgg acagaagtgg aactggccac actaacgtgg 3120 gtggacaggt ataacaatcg acgattgctg gaaaggctgg gccatattcc tccggcagaa 3180 gcagaaaaag cttattatgc ttccatcgga aataatgatc tggcagcctg agttcacaga 3240 taaaatactc tccaggaaac ccggggcggt tcagtctcag tccggattat gggggaaaat 3300 ttctcaatgg tccggtatca acaaccaggg ccgggaggat tacaggaaac gagattttgc 3360 cccggacagc cccgaaataa aattcagtga tcgcagggaa gcccttgaac tgatgacgca 3420 aatcgaatcg accgtgacca gcctgcaccg tgaggctgaa gcacagttcc ggcctgagct 3480 ggagaaaatc gtcagcggga ttgaaacagg ttttcgtggc acggccctgt acgccacaga 3540 aaacattgcc ggtcgcatca atgcccgcct ggaggatgag ggctttaccg taaaaatcag 3600 ttttccggca gtcagccagt tacagacccg gctcgcggta aaaataaatc tgagtgcgct 3660 tatggaggaa agaacggaga ccgtcacccg tcgccgtcgg cagagtggcg tatggggaac 3720 cgtttgtcga tggtttggca ccagtgacct gggctgggaa aactatgacg aggatgtgag 3780 tcgcagcgtg atcaatatca acaaggtcag agaggaagtt atgtcactga cccgggcata 3840 tttcggggag ctgcaggcat ccattgagca ggatattaac cagcccgtcc gccaggaaat 3900 cgatgccttt ttctgcgcat tcagggagaa agttgaacaa ctgcgtaaca cgctgattca 3960 gagctctgaa gatcataaac gcgatcagca ggcgcaggaa cggcttaccg ggcgacttca 4020 ggcattaaat gaaagggttc ctgagctcat tactgacagt aaggcgctga gggaagagct 4080 ggagacaatg ctgtgacttc accatttatt caacaaattg ctgataaccg ggtatgtcag 4140 gtactcacct gtcttcctga aaaatttgtg gttgatttcg caaacggaat cgatgttgca 4200 caggagcata tccgcacggc cggagagcgc acgttcttcc ggcgtttaaa agaggggctg 4260 accggcgaag gcgctgcacg gcagaatgcc atcaatgcgt cgcttgcaca gggcgttgag 4320 gcgtccctgc gctggctgac ggagatgaca acgtcacttg ccaccacaaa ctacgcgatt 4380 acccgggtaa acgacagggt cagttcactg gtcagtgata cagccaggct ggcgcattat 4440 tccgcagata cgcgggagca gttactcacc ctggccgatc aggttcacca taaactgaat 4500 catcttgaag aaaaactcca ccgtgttgac caggttcagc gggcgcagtt acatcttgag 4560 cagatattct catggtggag cgccgggcga tatgcgtcat tttcccctgc cggacgttgt 4620 tatgtggcac ttgaagagct tcgctggggc gcgtttggtg atgtgatacg tcagagcgaa 4680 acaggccagg ttaaccagct actggatatt ctcagacata aagcattaac gcagatggca 4740 caggagagtg gcggtagtgc aaccgtgcgt ctgaacactc tggactggct tggtggtcag 4800 ggccgggagc aggcagataa cgagtggcat gacgcgatta actggctggg agactggtgc 4860 agtgaagagc agcatccggt gatctggtca accacgcagg ctgcagaaca cttaccggtt 4920 cgcatgcctc gcctctgctc tgcagaacgc ctctctgaaa gtatggtcga tgaaatattt 4980 cagaaggggg ctgcatgagt acagaaatga aaacggggct ggtgctgtcc ggtggcgggg 5040 cggtgggcgc ttatcaggcg ggagtggtta aggcactggc agagtgtggt acacagatca 5100 gcatggtttc aggggccagc attggcgcat tcaatggtgc cattatcgcg gcctctaccg 5160 atctgtcaga agctgccgta cgcctggagg cgctctggga tcatctgggg aataatcagg 5220 tgctgtcggt aaacagattg gtttactttt cattgctgaa aaaattgttc caggcaatga 5280 acctctgcca gatccccgga cgtgcaggag cactgcttac gacgcttctt cgccatatat 5340 cgacaatcaa cgggtttgac aatctgatgg ctcagccgtt gttgtcagat gagcccctga 5400 cagcgctgat ggatcattat cttgatactg atgctctggc agacgggcta ccgctgtatg 5460 tgtcgctgta ccccacagaa gggggcatgc aggatattat tgactgcatt cgtgctgaac 5520 tgggtgtcgg aaccacgaaa aacgccgttt ttcagcatat ccagagcctg ccccgcggac 5580 agcagaaaga ggctctgctt gcgtcagccg cgctgcccct gctgttccgt ccccgtgagg 5640 ttcaggggac aatgttcggt gatggtggta tgggaggatg gcgaaatatg cagggaaata 5700 cccctgtgac gcctctggtc gatgccggat gcaatatggt gattgtgacg catctgagtg 5760 acggttcttt atgggatcgc caggcttttc cggacaccac aatccttgag atccgtcccc 5820 ggaaaaggct gaaatatgca ggtgatggtg gcaacagcgg cggtctgctc agttttacat 5880 cggcacatac cgacgcctgg tgtcagcagg gctatgaaga cacgatgctg gcgatggagc 5940 atatccggaa accgctggca gcacgtcagg cactgacccg gtcagaggcg gtattgcaga 6000 aaagcctgga tataacggaa gaggcagatt tggcactgag aaacgcgatg gcccggatta 6060 aataaagacg ccccaaagaa acgccaccgc ctgtggtggt gtttttcctg tctggtgtta 6120 ttgaaaatat tttcagatat atattacctg agagaaagtt ttacccctca cctgtcaatt 6180 cactcactgg aaatttaatt atgaaattac ctgtaaagtt attaatgagc cttatatctc 6240 tggtccgcgt tattgcacgt gccggggaat ataaaaatta cagccgggat gaaataaaat 6300 actggcgata tacatcatac aaggggggga aacttccgga aggtttcact gatgagaaat 6360 tttccagcgc catttacaac ggaagaatat ttacaatgaa acgtttacat acccttatgt 6420 tatttctggc ggttctgttc acgggcttta actttaacgc agaagcggct accgtaaaac 6480 aagctcttag ttgtaacccg gaagcctggg ctgaacaacc tggagcgtgt ccatcaacgt 6540 acgagttgta cgaaggtgac gctacctaca aagccgctat cgacaaagca ttaaaaccgg 6600 tcggactgag cggcatgttc ggtaaaggcg gctatatgga tggccctggt ggaggtatca 6660 cgccagtaaa cattaacggt acagtctggt tccagggcga cggttgcaaa gccaatacct 6720 gcggctggga ctttatcgta acactctata acccaaaaac ccatgaagtt gttggctacc 6780 gttactttgg tttagatgac ccggcctacc tggtttggtt cggtgaaatt ggcgtgcatg 6840 aattcgcgta tctggtgaaa aactacgtag ctgcggttaa ctaatttaag gagtctatca 6900 tgaaaacttt tatcaaaact ttactcgttg ctgtaactat tctgttctct gtcttcgcta 6960 ctgcgaaaca agtaaaactg ccaaataaca tcaaatacgt taatactaca gaagcgtttt 7020 cctgtaccga aattgacggt atgaattgcc agacaaagaa tcagttcaac tataaagata 7080 acagctatgt tttcgtgctt gaacgtggtg gtgcctggtg ctacgactac actgtctcgg 7140 tagttaacct gaaaaccggg aaagcacaaa tgattgaata cggggacaat caactgtgct 7200 caggtagcaa caaaccgttc ttcgaaatca aaaatggcgt accgacggta ggagtcatcg 7260 acacatccgg aaaacctgtc ggtgtagccc aggacaaact taaaatctaa ggagtaaacc 7320 atgcgtttct ctgcacatta ttaatatcaa aggtaaatac agccccagcc attgttaccg 7380 gaaagccgct taatgcgtgg ctcgccagtg aaaggcctct cagacaataa accttattca 7440 tttcacccgt caggccgcgt cttctccggg agacgcggct tttttcattt attgcaccag 7500 taaatcttaa ccaccgataa ggagcaaagt atgcgattag ccagtcgttt tggttatgct 7560 gcaaaccaga tacgccgtga ccgtccgctg acacatgaag aactgatacg ccatgtaccc 7620 agtatttttg gggaagaccg gcacacctcc cgcagtgaac ggtatgcgta cattcccacc 7680 attaccgtcc tggaaaatct gcagcgggaa ggctttcagc cgttcttcgc ctgccagacc 7740 cgtgtgcgcg acccgggccg ccggggatac acaaaacaca tgctgcgtct gcggcgggcc 7800 ggagagataa acggagaaca tgtccctgaa attattctgc tcaactctca tgacggtacc 7860 tccagctacc agatgctgcc gggttacttc aggttcgtct gccagaacgg gtgcgtctgt 7920 ggccagtctc tgggggaagt gcgtgttcca caccggggaa atgtagtgga gaaagttatc 7980 gaaggggctt acgaggtggt gggcgtgttt gaccggatag aggagaagcg tgatgccatg 8040 cagtcgctgg tcctgccgca accggcacgc caggcgctgg cacaggcggc actgacttac 8100 cgttatggtg acgaacatca gcccgtcacc accgccgaca ttctgacgcc gcgacgccgg 8160 gaggattacg gtaaggacct gtggagcgca tatcagacca tccaggagaa tatgctgaaa 8220 ggcgggattt ccggtcgcag tgcaaaagga aaacgtatcc atacccgggc cattcacagc 8280 attgataccg acattaagct caatcgcgca ttgtgggtga tggcagaaac gatgctggag 8340 agcctgcgct gatgccgttt ccctgagtga gggaatcatt cagctttcgt tcccgaaaaa 8400 cacacattta tttgttattt aaggagttat ctcatgaaaa ccgtttctca gaataccccc 8460 acaatttatt cagctacaac accagagaat aatccgcctc agttggttgc cagcctcgtc 8520 cctgatgaac agcgcatcag cttctggccg cagcattttg gcctcattcc acagtgggtc 8580 accctggagc cccgtgtctt cggctggatg gaccgtctgt gcgaagacta ctgcggtggt 8640 atctggaatc tgtacaccct gaacaacggc ggggcattta tggcccccga accggatgat 8700 gatgatgacg aaacatgggt actgttcaat gccatgaacg gtaaccgcgc tgaaatgagc 8760 ccggaagccg ccggtattgc cgcctgtctg atgacgtaca gccatcatgc ctgtcgtacg 8820 gagaattatg ccatgacggt ccattattac cggttgcggg attacgccct gcagcatccg 8880 gaaggcagcg ccattatgcg catcattgac tgaaaggggc cggaataatg caacagattt 8940 cctttctgcc c 8951 <210> 1349 <211> 55 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1621..1785) <400> 1349 Met Leu Ala Gly Arg Ile Asn Ile His Pro Gln Met Glu Asn Asn Val 1 5 10 15 Glu Lys Pro Ser Thr Asn Thr Ile Arg Ser Leu Ala Cys Pro Gln Ser 20 25 30 Gly Gln Ile Arg Thr Lys Asn Ser Ile Thr Ile Val Phe Val Ile Arg 35 40 45 Asn Ser Ile Gln Asn Leu * 50 <210> 1350 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2018..2344) <400> 1350 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Val 1 5 10 15 Arg Met Val Leu Glu Ser Gln Gly Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Ser Gly Asp Gly Gly 50 55 60 Leu Thr Thr Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1351 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2341..3231) <400> 1351 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala His Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Lys Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Val Ser Arg Lys 100 105 110 Ala Val Ser Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Cys Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Gln Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Thr Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Arg Tyr Asn Asn Arg Arg Leu Leu Glu Arg 260 265 270 Leu Gly His Ile Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asn Asp Leu Ala Ala * 290 295 <210> 1352 <211> 294 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3215..4096) <400> 1352 Met Ile Trp Gln Pro Glu Phe Thr Asp Lys Ile Leu Ser Arg Lys Pro 1 5 10 15 Gly Ala Val Gln Ser Gln Ser Gly Leu Trp Gly Lys Ile Ser Gln Trp 20 25 30 Ser Gly Ile Asn Asn Gln Gly Arg Glu Asp Tyr Arg Lys Arg Asp Phe 35 40 45 Ala Pro Asp Ser Pro Glu Ile Lys Phe Ser Asp Arg Arg Glu Ala Leu 50 55 60 Glu Leu Met Thr Gln Ile Glu Ser Thr Val Thr Ser Leu His Arg Glu 65 70 75 80 Ala Glu Ala Gln Phe Arg Pro Glu Leu Glu Lys Ile Val Ser Gly Ile 85 90 95 Glu Thr Gly Phe Arg Gly Thr Ala Leu Tyr Ala Thr Glu Asn Ile Ala 100 105 110 Gly Arg Ile Asn Ala Arg Leu Glu Asp Glu Gly Phe Thr Val Lys Ile 115 120 125 Ser Phe Pro Ala Val Ser Gln Leu Gln Thr Arg Leu Ala Val Lys Ile 130 135 140 Asn Leu Ser Ala Leu Met Glu Glu Arg Thr Glu Thr Val Thr Arg Arg 145 150 155 160 Arg Arg Gln Ser Gly Val Trp Gly Thr Val Cys Arg Trp Phe Gly Thr 165 170 175 Ser Asp Leu Gly Trp Glu Asn Tyr Asp Glu Asp Val Ser Arg Ser Val 180 185 190 Ile Asn Ile Asn Lys Val Arg Glu Glu Val Met Ser Leu Thr Arg Ala 195 200 205 Tyr Phe Gly Glu Leu Gln Ala Ser Ile Glu Gln Asp Ile Asn Gln Pro 210 215 220 Val Arg Gln Glu Ile Asp Ala Phe Phe Cys Ala Phe Arg Glu Lys Val 225 230 235 240 Glu Gln Leu Arg Asn Thr Leu Ile Gln Ser Ser Glu Asp His Lys Arg 245 250 255 Asp Gln Gln Ala Gln Glu Arg Leu Thr Gly Arg Leu Gln Ala Leu Asn 260 265 270 Glu Arg Val Pro Glu Leu Ile Thr Asp Ser Lys Ala Leu Arg Glu Glu 275 280 285 Leu Glu Thr Met Leu * 290 <210> 1353 <211> 302 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4093..4998) <400> 1353 Val Thr Ser Pro Phe Ile Gln Gln Ile Ala Asp Asn Arg Val Cys Gln 1 5 10 15 Val Leu Thr Cys Leu Pro Glu Lys Phe Val Val Asp Phe Ala Asn Gly 20 25 30 Ile Asp Val Ala Gln Glu His Ile Arg Thr Ala Gly Glu Arg Thr Phe 35 40 45 Phe Arg Arg Leu Lys Glu Gly Leu Thr Gly Glu Gly Ala Ala Arg Gln 50 55 60 Asn Ala Ile Asn Ala Ser Leu Ala Gln Gly Val Glu Ala Ser Leu Arg 65 70 75 80 Trp Leu Thr Glu Met Thr Thr Ser Leu Ala Thr Thr Asn Tyr Ala Ile 85 90 95 Thr Arg Val Asn Asp Arg Val Ser Ser Leu Val Ser Asp Thr Ala Arg 100 105 110 Leu Ala His Tyr Ser Ala Asp Thr Arg Glu Gln Leu Leu Thr Leu Ala 115 120 125 Asp Gln Val His His Lys Leu Asn His Leu Glu Glu Lys Leu His Arg 130 135 140 Val Asp Gln Val Gln Arg Ala Gln Leu His Leu Glu Gln Ile Phe Ser 145 150 155 160 Trp Trp Ser Ala Gly Arg Tyr Ala Ser Phe Ser Pro Ala Gly Arg Cys 165 170 175 Tyr Val Ala Leu Glu Glu Leu Arg Trp Gly Ala Phe Gly Asp Val Ile 180 185 190 Arg Gln Ser Glu Thr Gly Gln Val Asn Gln Leu Leu Asp Ile Leu Arg 195 200 205 His Lys Ala Leu Thr Gln Met Ala Gln Glu Ser Gly Gly Ser Ala Thr 210 215 220 Val Arg Leu Asn Thr Leu Asp Trp Leu Gly Gly Gln Gly Arg Glu Gln 225 230 235 240 Ala Asp Asn Glu Trp His Asp Ala Ile Asn Trp Leu Gly Asp Trp Cys 245 250 255 Ser Glu Glu Gln His Pro Val Ile Trp Ser Thr Thr Gln Ala Ala Glu 260 265 270 His Leu Pro Val Arg Met Pro Arg Leu Cys Ser Ala Glu Arg Leu Ser 275 280 285 Glu Ser Met Val Asp Glu Ile Phe Gln Lys Gly Ala Ala * 290 295 300 <210> 1354 <211> 357 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4995..6065) <400> 1354 Met Ser Thr Glu Met Lys Thr Gly Leu Val Leu Ser Gly Gly Gly Ala 1 5 10 15 Val Gly Ala Tyr Gln Ala Gly Val Val Lys Ala Leu Ala Glu Cys Gly 20 25 30 Thr Gln Ile Ser Met Val Ser Gly Ala Ser Ile Gly Ala Phe Asn Gly 35 40 45 Ala Ile Ile Ala Ala Ser Thr Asp Leu Ser Glu Ala Ala Val Arg Leu 50 55 60 Glu Ala Leu Trp Asp His Leu Gly Asn Asn Gln Val Leu Ser Val Asn 65 70 75 80 Arg Leu Val Tyr Phe Ser Leu Leu Lys Lys Leu Phe Gln Ala Met Asn 85 90 95 Leu Cys Gln Ile Pro Gly Arg Ala Gly Ala Leu Leu Thr Thr Leu Leu 100 105 110 Arg His Ile Ser Thr Ile Asn Gly Phe Asp Asn Leu Met Ala Gln Pro 115 120 125 Leu Leu Ser Asp Glu Pro Leu Thr Ala Leu Met Asp His Tyr Leu Asp 130 135 140 Thr Asp Ala Leu Ala Asp Gly Leu Pro Leu Tyr Val Ser Leu Tyr Pro 145 150 155 160 Thr Glu Gly Gly Met Gln Asp Ile Ile Asp Cys Ile Arg Ala Glu Leu 165 170 175 Gly Val Gly Thr Thr Lys Asn Ala Val Phe Gln His Ile Gln Ser Leu 180 185 190 Pro Arg Gly Gln Gln Lys Glu Ala Leu Leu Ala Ser Ala Ala Leu Pro 195 200 205 Leu Leu Phe Arg Pro Arg Glu Val Gln Gly Thr Met Phe Gly Asp Gly 210 215 220 Gly Met Gly Gly Trp Arg Asn Met Gln Gly Asn Thr Pro Val Thr Pro 225 230 235 240 Leu Val Asp Ala Gly Cys Asn Met Val Ile Val Thr His Leu Ser Asp 245 250 255 Gly Ser Leu Trp Asp Arg Gln Ala Phe Pro Asp Thr Thr Ile Leu Glu 260 265 270 Ile Arg Pro Arg Lys Arg Leu Lys Tyr Ala Gly Asp Gly Gly Asn Ser 275 280 285 Gly Gly Leu Leu Ser Phe Thr Ser Ala His Thr Asp Ala Trp Cys Gln 290 295 300 Gln Gly Tyr Glu Asp Thr Met Leu Ala Met Glu His Ile Arg Lys Pro 305 310 315 320 Leu Ala Ala Arg Gln Ala Leu Thr Arg Ser Glu Ala Val Leu Gln Lys 325 330 335 Ser Leu Asp Ile Thr Glu Glu Ala Asp Leu Ala Leu Arg Asn Ala Met 340 345 350 Ala Arg Ile Lys * 355 <210> 1355 <211> 228 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6201..6884) <400> 1355 Met Lys Leu Pro Val Lys Leu Leu Met Ser Leu Ile Ser Leu Val Arg 1 5 10 15 Val Ile Ala Arg Ala Gly Glu Tyr Lys Asn Tyr Ser Arg Asp Glu Ile 20 25 30 Lys Tyr Trp Arg Tyr Thr Ser Tyr Lys Gly Gly Lys Leu Pro Glu Gly 35 40 45 Phe Thr Asp Glu Lys Phe Ser Ser Ala Ile Tyr Asn Gly Arg Ile Phe 50 55 60 Thr Met Lys Arg Leu His Thr Leu Met Leu Phe Leu Ala Val Leu Phe 65 70 75 80 Thr Gly Phe Asn Phe Asn Ala Glu Ala Ala Thr Val Lys Gln Ala Leu 85 90 95 Ser Cys Asn Pro Glu Ala Trp Ala Glu Gln Pro Gly Ala Cys Pro Ser 100 105 110 Thr Tyr Glu Leu Tyr Glu Gly Asp Ala Thr Tyr Lys Ala Ala Ile Asp 115 120 125 Lys Ala Leu Lys Pro Val Gly Leu Ser Gly Met Phe Gly Lys Gly Gly 130 135 140 Tyr Met Asp Gly Pro Gly Gly Gly Ile Thr Pro Val Asn Ile Asn Gly 145 150 155 160 Thr Val Trp Phe Gln Gly Asp Gly Cys Lys Ala Asn Thr Cys Gly Trp 165 170 175 Asp Phe Ile Val Thr Leu Tyr Asn Pro Lys Thr His Glu Val Val Gly 180 185 190 Tyr Arg Tyr Phe Gly Leu Asp Asp Pro Ala Tyr Leu Val Trp Phe Gly 195 200 205 Glu Ile Gly Val His Glu Phe Ala Tyr Leu Val Lys Asn Tyr Val Ala 210 215 220 Ala Val Asn * 225 <210> 1356 <211> 137 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6900..7310) <400> 1356 Met Lys Thr Phe Ile Lys Thr Leu Leu Val Ala Val Thr Ile Leu Phe 1 5 10 15 Ser Val Phe Ala Thr Ala Lys Gln Val Lys Leu Pro Asn Asn Ile Lys 20 25 30 Tyr Val Asn Thr Thr Glu Ala Phe Ser Cys Thr Glu Ile Asp Gly Met 35 40 45 Asn Cys Gln Thr Lys Asn Gln Phe Asn Tyr Lys Asp Asn Ser Tyr Val 50 55 60 Phe Val Leu Glu Arg Gly Gly Ala Trp Cys Tyr Asp Tyr Thr Val Ser 65 70 75 80 Val Val Asn Leu Lys Thr Gly Lys Ala Gln Met Ile Glu Tyr Gly Asp 85 90 95 Asn Gln Leu Cys Ser Gly Ser Asn Lys Pro Phe Phe Glu Ile Lys Asn 100 105 110 Gly Val Pro Thr Val Gly Val Ile Asp Thr Ser Gly Lys Pro Val Gly 115 120 125 Val Ala Gln Asp Lys Leu Lys Ile * 130 135 <210> 1357 <211> 274 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7531..8352) <400> 1357 Met Arg Leu Ala Ser Arg Phe Gly Tyr Ala Ala Asn Gln Ile Arg Arg 1 5 10 15 Asp Arg Pro Leu Thr His Glu Glu Leu Ile Arg His Val Pro Ser Ile 20 25 30 Phe Gly Glu Asp Arg His Thr Ser Arg Ser Glu Arg Tyr Ala Tyr Ile 35 40 45 Pro Thr Ile Thr Val Leu Glu Asn Leu Gln Arg Glu Gly Phe Gln Pro 50 55 60 Phe Phe Ala Cys Gln Thr Arg Val Arg Asp Pro Gly Arg Arg Gly Tyr 65 70 75 80 Thr Lys His Met Leu Arg Leu Arg Arg Ala Gly Glu Ile Asn Gly Glu 85 90 95 His Val Pro Glu Ile Ile Leu Leu Asn Ser His Asp Gly Thr Ser Ser 100 105 110 Tyr Gln Met Leu Pro Gly Tyr Phe Arg Phe Val Cys Gln Asn Gly Cys 115 120 125 Val Cys Gly Gln Ser Leu Gly Glu Val Arg Val Pro His Arg Gly Asn 130 135 140 Val Val Glu Lys Val Ile Glu Gly Ala Tyr Glu Val Val Gly Val Phe 145 150 155 160 Asp Arg Ile Glu Glu Lys Arg Asp Ala Met Gln Ser Leu Val Leu Pro 165 170 175 Gln Pro Ala Arg Gln Ala Leu Ala Gln Ala Ala Leu Thr Tyr Arg Tyr 180 185 190 Gly Asp Glu His Gln Pro Val Thr Thr Ala Asp Ile Leu Thr Pro Arg 195 200 205 Arg Arg Glu Asp Tyr Gly Lys Asp Leu Trp Ser Ala Tyr Gln Thr Ile 210 215 220 Gln Glu Asn Met Leu Lys Gly Gly Ile Ser Gly Arg Ser Ala Lys Gly 225 230 235 240 Lys Arg Ile His Thr Arg Ala Ile His Ser Ile Asp Thr Asp Ile Lys 245 250 255 Leu Asn Arg Ala Leu Trp Val Met Ala Glu Thr Met Leu Glu Ser Leu 260 265 270 Arg * <210> 1358 <211> 160 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(8434..8913) <400> 1358 Met Lys Thr Val Ser Gln Asn Thr Pro Thr Ile Tyr Ser Ala Thr Thr 1 5 10 15 Pro Glu Asn Asn Pro Pro Gln Leu Val Ala Ser Leu Val Pro Asp Glu 20 25 30 Gln Arg Ile Ser Phe Trp Pro Gln His Phe Gly Leu Ile Pro Gln Trp 35 40 45 Val Thr Leu Glu Pro Arg Val Phe Gly Trp Met Asp Arg Leu Cys Glu 50 55 60 Asp Tyr Cys Gly Gly Ile Trp Asn Leu Tyr Thr Leu Asn Asn Gly Gly 65 70 75 80 Ala Phe Met Ala Pro Glu Pro Asp Asp Asp Asp Asp Glu Thr Trp Val 85 90 95 Leu Phe Asn Ala Met Asn Gly Asn Arg Ala Glu Met Ser Pro Glu Ala 100 105 110 Ala Gly Ile Ala Ala Cys Leu Met Thr Tyr Ser His His Ala Cys Arg 115 120 125 Thr Glu Asn Tyr Ala Met Thr Val His Tyr Tyr Arg Leu Arg Asp Tyr 130 135 140 Ala Leu Gln His Pro Glu Gly Ser Ala Ile Met Arg Ile Ile Asp * 145 150 155 <210> 1359 <211> 8124 <212> DNA <213> Escherichia coli O157:H7 <400> 1359 ttgttgtccg aagcctaacc aggtgaacgg tccctcaaga cagatgggga ccgtttatgt 60 gctattttta tgccgcatcc gctaaaacaa acatcccgta aggatggatt tcgaggtaat 120 agtgctcacc aatatcgggc tgtaaacggg tggcgtttac ttgtaataaa atctcctgtc 180 catgccactc tacggtcact tcgtactgcg gccccatgta ggcgacatgg cgaataacac 240 aacgctgact ctcttcgccg tgattgctta aggtgatggc ttccgggcga acgccgacgg 300 tgccgctacc ttgcaccggg aaatgcgccg cgcgcggcag gcgataaccg tagatatcga 360 catactcttc gctaaagttc gccgggaaca ggttggcgtc gcccataaaa cttgccataa 420 agcgggaggc tggctgacga tagagatcct gcggtgagcc aatctgcatg atgtgacctt 480 tattcatcac cagcacagtg tcggaaaccg cgaaggcctc actttgatcg tgagtcacgt 540 agagcgacgt gatattaaac tgcttttgca gctcgcggat cttatcgcgc atgctgcggc 600 gcaggttggc atcgaggtta cttaacggct catcaaacag cagcaccttt ggtttgagga 660 tcaacgcgcg ggccagcgcc acgcgctgtt gctgaccacc ggaaatctgg tcgacatagc 720 ggtcctcgaa cccttccaga tccaccattg ccagcgcctc tttcacccgc tgctttactt 780 cgctacgcga cacgccgagc atctttaacc cgtagccgac gttttcgccc agcgacatat 840 gcgggaacag agcgtatgac tgaaacacca tgcagatatc gcgctgctga atggaacgat 900 gcgtgacatc ttcgccatca ataaagattt gcccttcact cggtttttcc agcccggcaa 960 ccagacgcaa aatggtggtt ttgccgcagc cggaagggcc aagcagcgtc accatttgcc 1020 cttgtgggat ggtgagattg atattgtcga taaccgtatt actgccgaat cgtttagtga 1080 cgttgcgcag ttccacaaaa tttttctgac tcatagtgcg ctccattacg cctggttttt 1140 ggctttagaa cgggagatac gtgcttctcc gatcagccag tcaaagagga aaataatcgc 1200 cagcatcacc acgatcagaa tcgaaccata ggcgatggct acgccatatt cgccgtcttc 1260 aacgcggtta agaatgtagg cggttgccac gcgggtgtcc ggcgtgacga gaaagacgat 1320 ggcgctgacc gtcgtgatgg cccgcacaaa gctgtagatc agggccgaga gaatggccgg 1380 acgcagcagc ggcagtaaaa tgtgggttat ggttcgcaag gaacccgcgc gcaggctgag 1440 tgaggcttca tccagcgatt tgtcgatctg ccccaggcct gcaatcccgg cgcgaatacc 1500 caccggaacg ttacgcatca ccatcgagat aatcacaatt gccgccgttc cggtgagata 1560 aaccggagcg ctgttaaagg caagaatata cgaaacgccc gccaccgtac ccggtacggc 1620 aaagcacagc atggtggtga actcgatggt ctttttgcct ttgaattgtt gacgcaccac 1680 cacccaggcg atgagcaggc caaagatagc ggtaatggga gcggcaatcc cggcgtagag 1740 cagggtatcc agcagtgaag gccacgcgcc gtcgctcatt ccctgaccaa atagcttgat 1800 aaagttatcc agcgtcaggg tgtagtccac gccccagttc accgtgaagc tgccgtagaa 1860 aatgctgccg tagagcaggg cgttaaaggc aatccatatc gcaagtatgg cgaccacgct 1920 ccacaccagg gtgaccggaa gcggctggac gtcgccacgg taggatttgc cggaaaccgt 1980 gacgtaagag cgtttaccaa tccacatata ctgtatgcag aacaccagca gcgagaacag 2040 cagcaggaaa gcgccaaggg tgctggcggc ctgataatcc agctgcgagc cggtaatata 2100 gaagtaaatt tgcgtcgcca gtacgtcgaa gttaccgcca agtaccagcg ggttactgaa 2160 atcagccagt gactgtacca cgacgattaa aaaggcattg gcgagcgcgg gcttcaacaa 2220 cggcacaaac acgccgttaa aggtttgcca gcggctggcg cgcagggtgt aggaggcctc 2280 ttccagcgag ggatgaatgg ttttaatggc cccgtcgagg atcataaatg ccattggcgt 2340 gaatgccaga acctgtgcca gccagatccc ggtaaaaccg tacagccagt tggtgttggt 2400 cagcccaaac cactccacca taaattccgt aacatagccg gaacgcccca tcatgagcgt 2460 cacgcctaag ccgaccacaa acggtggcgt aacgatgggc aaaatggaaa agatgcgacc 2520 aataatggcg ctgcgtttag cgatgcgcgt ggtataaatc gccagcacca ggccgaagaa 2580 agcacagcct atccccaccg ctatcgacaa gacgatagag ttgacgatca cctgaacaat 2640 atgtgcctgc gagagcacgg tcataaacgc cagcggggcg agctctcccg cgtcgttggt 2700 gaacatcggg ataaaaatgg cgatgctcgg ccagacgata aaaatgccaa tcagcgccac 2760 aatcgcaatc agtgagccga tcacgaagcg gtcgccgccc agccattcga ggcgggttaa 2820 ggccagcgtc ataatcgcgc ctagttcgac aaacagcacg atggcggcgt agcctaaacc 2880 gcgtccagcc acggtggcgc tgatgacgat aaacgccata cagagcaatg cccagccggc 2940 atcgaaataa tgacgactac gctgttcgcg cgtggcctga cgaaacgggc ggaccagcaa 3000 caggctcggg agtaaatacc acagccagct gatattaaaa tgcgaccagc cgtacgcccc 3060 gaggatctca tcactcgtgg attccagcag gccataatcg aggctccagc tcggcaacag 3120 gacaaatgcc agccagccca gcaaaaccca aaggaaaatc gcatcccgct ttttcacggg 3180 atggagtgca agtgtctgtg acatagcagt tccggtatgg ttggccgggg caggcgtctg 3240 cgctgcaccc ggcaaatgcg cctaatgcgg gtttatttac ccatcttcac ttcgctgacc 3300 catttattaa tcaatgcctt acgaacatcc gtggaaccat atttatccat gtcgtagttg 3360 attaatttca ggtcgtcgag cttcagcgaa tttggcgacg tttcggcggt ggtattagtc 3420 aggatctgat aagacttccc tttcttccac gccagttcct gagcttcttt tgataatacc 3480 cagtccacaa acagtttggc gttgtcgagg ttgcgcgcgc ctttcagaat gctgacgccg 3540 ccaatttcgt agcccgtacc ttcacacggg gaaatcaact ccagcggcgc gccctgttct 3600 ttttccagcg agtagtcatg caggaagcca ataccaatcg ccgtttcgcc acgggcggcg 3660 ttacgtgccg gggctatgcc tgatttggtg tactgagaga cgttggcgtt cagttgtttt 3720 agataatcaa aggcctgatc ttccccccac agctgcgcaa aagtagccag ggcggtgtag 3780 gcagtaccgg aactttgcgg atcggcaatt tgaatttcgc ctttatattc cggtttggtg 3840 agatctttcc agcacttcgg caccggcagg tttttctctt tcagacgatc ggtgtttacg 3900 ccaaaaccga ggatccccac ataaacggca gaggacagat tccctttcac ttttgccgga 3960 tcgcggaatt tctccatgat ctgctcaagg ttaggggatt tatacgcctg tagcaggccc 4020 atctcgccag cctgcgattg cgggtctaaa gtgccgccgt accagacgtc agcctggggg 4080 tttttctttt cagcatcgac ttttgccagg gtgcttccgg aaccgttgcg gataaacgag 4140 gtttttacat catatttctc gccaaacgct ttggtttcgg cctcacacat ttcattggtg 4200 gcgctgcaat agaccaccag ccggcctttt gcctgcgcgg cacccgttaa agtcgccagc 4260 gcaacggcag aagcaatcag agtagaggta aaggtcattt tcattgtttt atccttcgag 4320 cgtgagtggt ggtgatgccc gccatcagta acggcatcag cagtaaaccc ataagtactg 4380 cggcgaccga gagtaaactg aacattcccg gccagccgta gcgttcgatg accagcgaca 4440 gcggccagcc tgccagcgcc gcgccaaggt aagcgaacag gccgagaaat ccggtgattg 4500 aacccgccgc agctttgtgc ccacactcca ccgccgcaag tccaatcagc atttgtgggc 4560 caaagacgaa aaagcccacg gtaaaaaagc acactgccag cagagcgtag tgatgaaccg 4620 gtgccagcca cagtgcggcg actgacacca tcaaccccaa cgtgaacagc aaaatcattg 4680 gcgctcgttg cccgctaaac agcaaatccg atccccatcc ggcaaataac gcgccgagta 4740 agccgcccac ttcaaacagc attaccgtgg cgttggcgct gagcaggttg acaccgtggc 4800 tttccgtcag ccagatattg ccccagtcgt taagcgcaat ccggatcaca taaaccagta 4860 catatgagac gcccagtagc cagatcagcg gattttgcag catggtggtg cgcaacattt 4920 gccacagccc catcggcgga ctttgttgtt cctgacgtaa ctccagcgga tcgtgacgcc 4980 agtgaccaac tgtcggtaat ccctcttcct ggggcgtgcc tttgagttgt agcgttaacc 5040 agatccctaa tgccatgctg attatccccg gtgtcagcat cgcggcctgc cagccccacc 5100 agtgggcggc aaaggcgcta atcagcggaa taatcgctcc gccaatgttg atcgacatat 5160 tccagcagcc ccaccagaaa ccgcgctcat tgcgtgagta ccagtgggtc agcaagcggg 5220 cacacggtgg ccatccccag ccctgaaaaa aaccgttcag tgtccagacc acaagcagaa 5280 gcgtaagtga ttcgccaaag gcaaacacca cgttcaataa cccggtggcg aacaagccga 5340 cgcccataaa accgcgttgt ccgtggctgt catgccacag tccggcggta aatttcgaca 5400 atccgtagct gagataaaac agcgaaccca gcaggccaat gtcgccttta tccagtccga 5460 ggtcggtttg tagcgccgga aggacgtaat tcacgctttt tcgcgtcaga taaaatgcgg 5520 cgtagccaat aatcatgcac atcagcaatc gcggacgtaa tgtccggtag cattgattaa 5580 tttctctcgc tgaacgcgcg tgcatggttg tctccatgtt gctgactata tgaaaatgaa 5640 agtgaaaggg gatgagagaa aatccgggat acctaagact ttttcctggt tatccggcga 5700 tttgttgcaa aaatgtgggc aagttaacaa ttacccgcgt gccgtgctgt ttttcgagcg 5760 ttaagtcgcc gcccagggcg ctgacgcgct cacgcatccc ctgaatgcca aatccagcca 5820 ttttcccgct ggcgatcccc acaccgttgt cgctgacttc cagatgcaat acctctccct 5880 gctggcgcag gataatcgtc acttcgctgg cttcggcgtg tttacagatg ttattgagca 5940 actcctgcaa taaccgatac aaggtaaagc gcaccgtttc gttttctggt gtggagttca 6000 gttgataggc aaactggcaa tgaatgccgc gttcactaaa ggcaaattca ttaatcagat 6060 gcagcaacgc ttcgcgaaat gtcagttcat caagcgcggg aggccgcaac tggcgcagca 6120 attggcgggt ggagagatga atgcggcggg cgagctcatt gatttggctg gctgcggatt 6180 gaatttgcgc cggatcacgc gcccgcttca ccagttgcga ctggatctga atggcggtga 6240 tgttctgacc gatttcgtcg tgcagctctc gcgccaggtt ttttcgcgtg tcctcctcgg 6300 tgtggatcag cttttccgcc aatgcccgcc gcgctgccag ctcggcctcc agccgttgtc 6360 ggtaatggtg caggtttagc gccagatgtt gctggcgact gatggcaatg cccaggccaa 6420 ttcccagcaa ggcctgggtc gcgaggaaaa tctccagctc caccaggtta ctaaagccca 6480 cgccaatctg gcgggcgatg gtgatcatca tgctgcccaa aagcccggag agtacgccac 6540 cttgccagcc aaatttccac gccatcacca cattgggcaa aaagaccacg atcaacagca 6600 gacgttcaat ttcaggtgac agcaccatct gagtgccgat accaataata aaaaacaggc 6660 tacaccagat gattaaagag gtacgcaagg ggggattatg cgtatcgagt cccaggagct 6720 ggtagcgatg ctgctggcgc agaaactcaa agataagata gacaaacggc gtcagtaata 6780 cgccgccggt aaatgaggtc aaacccggta gcattattgg gcctgacata aaaggggaga 6840 gcagggcggt attcaacaat gaagctgccg tgacagtggc taacagcaac gtcagacgct 6900 gccagtaaag tggaaaacgg tgccagaagt tttgcgcaag gagggcagga aacaggctaa 6960 taaccggcgt tgccagcatg agataaccgt tcaatagctg ttcactatgg agccagaaca 7020 tcatcagcaa aggggggagc accaacgcag gccagtagcg gcgagagagc aaaataacaa 7080 gggcgagata aactccctgc gggagaaaca acaccgcctg ttgaccgtta ttggtcagat 7140 aaaagctgag cgtccacagc atcagccagc cggttcccca ggctagcaca ataaacagca 7200 aaatcaccca atgacgaaga ttgcgcgaca ttaatgcccc gccagcagat ggtggtcgag 7260 cgcaaaatgt accagttcaa tggtgctatg gcagttcagt tttcccagca cattggcgcg 7320 atgcacatgt accgttttat gactgagttc gagtttaaag gcgatctctt taacgctgtc 7380 tcctttgacc agtaactcaa acacttcacg ttctcgtggg gtgagaattt ccagcgcctg 7440 ggcgggttgc ccgccgccgc gtaaagcccg aatcgcatcg gcacagagat aatgcccgcc 7500 cagcccgacc gagcgcaccg cctgtactaa ctcttccggc ccacagcgtt tggttaaata 7560 cccgctggca ccggcatcca gcgcgctttg cacaaaggtt ggcgcgtcat aaatgctaag 7620 aataatggcg cgaaattgcg gtttttgtgc acgcaggcgc ttaagcaaac tgaggccgtt 7680 ttcgtccggc atggcaatat caatgacggc aacattgacg tcatcacgga ttaatgccga 7740 ccatgcctgc gcggcactac tgtactgacc aatgacctcc agatcgtctt ccagagagag 7800 taattgtgcg aagccagagc gcaccacaac atggtcatcc accagcacta cccgaatcat 7860 acttttcttc tcttattatc taattctcct atcatgcatc acggcgcggc gctggcaatc 7920 aaccagcgac agatatggaa tggatgtaac aaaatggcaa taatttgccg gagcgcgcac 7980 atcttatctg gcttgtgaac cggcgggata cgttcgccaa aaccgcaaaa tgcgcaaact 8040 cgctaaccat tgccgatttt tttctaaaaa cgctttgttc ttaacaagac cttttaattc 8100 ctttatcaaa ctgacccgca acga 8124 <210> 1360 ＜２１１＞ ３５３ ＜２１２＞ ＰＲＴ ＜２１３＞ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ Ｏ１５７：Ｈ７ ＜２２１＞ ＣＤＳ ＜２２２＞ ｃｏｍｐｌｅｍｅｎｔ（６８．．１１２６） ＜４００＞ １３６０ Ｍｅｔ Ｇｌｕ Ａｒｇ Ｔｈｒ Ｍｅｔ Ｓｅｒ Ｇｌｎ Ｌｙｓ Ａｓｎ
Ｐｈｅ Ｖａｌ Ｇｌｕ Ｌｅｕ Ａｒｇ Ａｓｎ Ｖａｌ １ ５
１０ １５ Ｔｈｒ Ｌｙｓ Ａｒｇ Ｐｈｅ Ｇｌｙ Ｓｅｒ Ａｓｎ Ｔｈｒ Ｖａｌ
Ｉｌｅ Ａｓｐ Ａｓｎ Ｉｌｅ Ａｓｎ Ｌｅｕ Ｔｈｒ ２０ ２５
３０ Ｉｌｅ Ｐｒｏ Ｇｌｎ Ｇｌｙ Ｇｌｎ Ｍｅｔ Ｖａｌ Ｔｈｒ Ｌｅｕ
Ｌｅｕ Ｇｌｙ Ｐｒｏ Ｓｅｒ Ｇｌｙ Ｃｙｓ Ｇｌｙ ３５ ４０
４５ Ｌｙｓ Ｔｈｒ Ｔｈｒ Ｉｌｅ Ｌｅｕ Ａｒｇ Ｌｅｕ Ｖａｌ Ａｌａ
Ｇｌｙ Ｌｅｕ Ｇｌｕ Ｌｙｓ Ｐｒｏ Ｓｅｒ Ｇｌｕ ５０ ５５
６０ Ｇｌｙ Ｇｌｎ Ｉｌｅ Ｐｈｅ Ｉｌｅ Ａｓｐ Ｇｌｙ Ｇｌｕ Ａｓｐ
Ｖａｌ Ｔｈｒ Ｈｉｓ Ａｒｇ Ｓｅｒ Ｉｌｅ Ｇｌｎ ６５ ７０
７５ ８０ Ｇｌｎ Ａｒｇ Ａｓｐ Ｉｌｅ Ｃｙｓ Ｍｅｔ Ｖａｌ Ｐｈｅ Ｇｌｎ
Ｓｅｒ Ｔｙｒ Ａｌａ Ｌｅｕ Ｐｈｅ Ｐｒｏ Ｈｉｓ ８５
９０ ９５ Ｍｅｔ Ｓｅｒ Ｌｅｕ Ｇｌｙ Ｇｌｕ Ａｓｎ Ｖａｌ Ｇｌｙ Ｔｙｒ
Ｇｌｙ Ｌｅｕ Ｌｙｓ Ｍｅｔ Ｌｅｕ Ｇｌｙ Ｖａｌ １００ １０５
１１０ Ｓｅｒ Ａｒｇ Ｓｅｒ Ｇｌｕ Ｖａｌ Ｌｙｓ Ｇｌｎ Ａｒｇ Ｖａｌ
Ｌｙｓ Ｇｌｕ Ａｌａ Ｌｅｕ Ａｌａ Ｍｅｔ Ｖａｌ １１５ １２０
１２５ Ａｓｐ Ｌｅｕ Ｇｌｕ Ｇｌｙ Ｐｈｅ Ｇｌｕ Ａｓｐ Ａｒｇ Ｔｙｒ
Ｖａｌ Ａｓｐ Ｇｌｎ Ｉｌｅ Ｓｅｒ Ｇｌｙ Ｇｌｙ １３０ １３５
１４０ Ｇｌｎ Ｇｌｎ Ｇｌｎ Ａｒｇ Ｖａｌ Ａｌａ Ｌｅｕ Ａｌａ Ａｒｇ
Ａｌａ Ｌｅｕ Ｉｌｅ Ｌｅｕ Ｌｙｓ Ｐｒｏ Ｌｙｓ １４５ １５０
１５５ １６０ 165 170 175 Arg Ser Met Arg Asp Lys Ile Arg Glu Leu Gln Lys Gln Phe Asn Ile 180 185 190 Thr Ser Leu Tyr Val Thr His Asp Gln Ser Glu Ala Phe Ala Val Ser 195 200 205 Asp Thr Val Leu Val Met Asn Lys Gly His Ile Met Gln Ile Gly Ser 210 215 220 Pro Gln Asp Leu Tyr Arg Gln Pro Ala Ser Arg Phe Met Ala Ser Phe 225 230 235 240 Met Gly Asp Ala Asn Leu Phe Pro Ala Asn Phe Ser Glu Glu Tyr Val 245 250 255 Asp Ile Tyr Gly Tyr Arg Leu Pro Arg Ala Ala His Phe Pro Val Gln 260 265 270 Gly Ser Gly Thr Val Gly Val Arg Pro Glu Ala Ile Thr Leu Ser Asn 275 280 285 His Gly Glu Glu Ser Gln Arg Cys Val Ile Arg His Val Ala Tyr Met 290 295 300 Gly Pro Gln Tyr Glu Val Thr Val Glu Trp His Gly Gln Glu Ile Leu 305 310 315 320 Leu Gln Val Asn Ala Thr Arg Leu Gln Pro Asp Ile Gly Glu His Tyr 325 330 335 Tyr Leu Glu Ile His Pro Tyr Gly Met Phe Val Leu Ala Asp Ala Ala 340 345 350 * <210> 1361 <211> 693 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1126..3204) <400> 1361 Met Ser Gln Thr Leu Ala Leu His Pro Val Lys Lys Arg Asp Ala Ile 1 5 10 15 Phe Leu Trp Val Leu Leu Gly Trp Leu Ala Phe Val Leu Leu Pro Ser 20 25 30 Trp Ser Leu Asp Tyr Gly Leu Leu Glu Ser Thr Ser Asp Glu Ile Leu 35 40 45 Gly Ala Tyr Gly Trp Ser His Phe Asn Ile Ser Trp Leu Trp Tyr Leu 50 55 60 Leu Pro Ser Leu Leu Leu Val Arg Pro Phe Arg Gln Ala Thr Arg Glu 65 70 75 80 Gln Arg Ser Arg His Tyr Phe Asp Ala Gly Trp Ala Leu Leu Cys Met 85 90 95 Ala Phe Ile Val Ile Ser Ala Thr Val Ala Gly Arg Gly Leu Gly Tyr 100 105 110 Ala Ala Ile Val Leu Phe Val Glu Leu Gly Ala Ile Met Thr Leu Ala 115 120 125 Leu Thr Arg Leu Glu Trp Leu Gly Gly Asp Arg Phe Val Ile Gly Ser 130 135 140 Leu Ile Ala Ile Val Ala Leu Ile Gly Ile Phe Ile Val Trp Pro Ser 145 150 155 160 Ile Ala Ile Phe Ile Pro Met Phe Thr Asn Asp Ala Gly Glu Leu Ala 165 170 175 Pro Leu Ala Phe Met Thr Val Leu Ser Gln Ala His Ile Val Gln Val 180 185 190 Ile Val Asn Ser Ile Val Leu Ser Ile Ala Val Gly Ile Gly Cys Ala 195 200 205 Phe Phe Gly Leu Val Leu Ala Ile Tyr Thr Thr Arg Ile Ala Lys Arg 210 215 220 Ser Ala Ile Ile Gly Arg Ile Phe Ser Ile Leu Pro Ile Val Thr Pro 225 230 235 240 Pro Phe Val Val Gly Leu Gly Val Thr Leu Met Met Gly Arg Ser Gly 245 250 255 Tyr Val Thr Glu Phe Met Val Glu Trp Phe Gly Leu Thr Asn Thr Asn 260 265 270 Trp Leu Tyr Gly Phe Thr Gly Ile Trp Leu Ala Gln Val Leu Ala Phe 275 280 285 Thr Pro Met Ala Phe Met Ile Leu Asp Gly Ala Ile Lys Thr Ile His 290 295 300 Pro Ser Leu Glu Glu Ala Ser Tyr Thr Leu Arg Ala Ser Arg Trp Gln 305 310 315 320 Thr Phe Asn Gly Val Phe Val Pro Leu Leu Lys Pro Ala Leu Ala Asn 325 330 335 Ala Phe Leu Ile Val Val Val Gln Ser Leu Ala Asp Phe Ser Asn Pro 340 345 350 Leu Val Leu Gly Gly Asn Phe Asp Val Leu Ala Thr Gln Ile Tyr Phe 355 360 365 Tyr Ile Thr Gly Ser Gln Leu Asp Tyr Gln Ala Ala Ser Thr Leu Gly 370 375 380 Ala Phe Leu Leu Leu Phe Ser Leu Leu Val Phe Cys Ile Gln Tyr Met 385 390 395 400 Trp Ile Gly Lys Arg Ser Tyr Val Thr Val Ser Gly Lys Ser Tyr Arg 405 410 415 Gly Asp Val Gln Pro Leu Pro Val Thr Leu Val Trp Ser Val Val Ala 420 425 430 Ile Leu Ala Ile Trp Ile Ala Phe Asn Ala Leu Leu Tyr Gly Ser Ile 435 440 445 Phe Tyr Gly Ser Phe Thr Val Asn Trp Gly Val Asp Tyr Thr Leu Thr 450 455 460 Leu Asp Asn Phe Ile Lys Leu Phe Gly Gln Gly Met Ser Asp Gly Ala 465 470 475 480 Trp Pro Ser Leu Leu Asp Thr Leu Leu Tyr Ala Gly Ile Ala Ala Pro 485 490 495 Ile Thr Ala Ile Phe Gly Leu Leu Ile Ala Trp Val Val Val Arg Gln 500 505 510 Gln Phe Lys Gly Lys Lys Thr Ile Glu Phe Thr Thr Met Leu Cys Phe 515 520 525 Ala Val Pro Gly Thr Val Ala Gly Val Ser Tyr Ile Leu Ala Phe Asn 530 535 540 Ser Ala Pro Val Tyr Leu Thr Gly Thr Ala Ala Ile Val Ile Ile Ser 545 550 555 560 Met Val Met Arg Asn Val Pro Val Gly Ile Arg Ala Gly Ile Ala Gly 565 570 575 Leu Gly Gln Ile Asp Lys Ser Leu Asp Glu Ala Ser Leu Ser Leu Arg 580 585 590 Ala Gly Ser Leu Arg Thr Ile Thr His Ile Leu Leu Pro Leu Leu Arg 595 600 605 Pro Ala Ile Leu Ser Ala Leu Ile Tyr Ser Phe Val Arg Ala Ile Thr 610 615 620 Thr Val Ser Ala Ile Val Phe Leu Val Thr Pro Asp Thr Arg Val Ala 625 630 635 640 Thr Ala Tyr Ile Leu Asn Arg Val Glu Asp Gly Glu Tyr Gly Val Ala 645 650 655 Ile Ala Tyr Gly Ser Ile Leu Ile Val Val Met Leu Ala Ile Ile Phe 660 665 670 Leu Phe Asp Trp Leu Ile Gly Glu Ala Arg Ile Ser Arg Ser Lys Ala 675 680 685 Lys Asn Gln Ala * 690 <210> 1362 <211> 344 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3273..4304) <400> 1362 Met Lys Met Thr Phe Thr Ser Thr Leu Ile Ala Ser Ala Val Ala Leu 1 5 10 15 Ala Thr Leu Thr Gly Ala Ala Gln Ala Lys Gly Arg Leu Val Val Tyr 20 25 30 Cys Ser Ala Thr Asn Glu Met Cys Glu Ala Glu Thr Lys Ala Phe Gly 35 40 45 Glu Lys Tyr Asp Val Lys Thr Ser Phe Ile Arg Asn Gly Ser Gly Ser 50 55 60 Thr Leu Ala Lys Val Asp Ala Glu Lys Lys Asn Pro Gln Ala Asp Val 65 70 75 80 Trp Tyr Gly Gly Thr Leu Asp Pro Gln Ser Gln Ala Gly Glu Met Gly 85 90 95 Leu Leu Gln Ala Tyr Lys Ser Pro Asn Leu Glu Gln Ile Met Glu Lys 100 105 110 Phe Arg Asp Pro Ala Lys Val Lys Gly Asn Leu Ser Ser Ala Val Tyr 115 120 125 Val Gly Ile Leu Gly Phe Gly Val Asn Thr Asp Arg Leu Lys Glu Lys 130 135 140 Asn Leu Pro Val Pro Lys Cys Trp Lys Asp Leu Thr Lys Pro Glu Tyr 145 150 155 160 Lys Gly Glu Ile Gln Ile Ala Asp Pro Gln Ser Ser Gly Thr Ala Tyr 165 170 175 Thr Ala Leu Ala Thr Phe Ala Gln Leu Trp Gly Glu Asp Gln Ala Phe 180 185 190 Asp Tyr Leu Lys Gln Leu Asn Ala Asn Val Ser Gln Tyr Thr Lys Ser 195 200 205 Gly Ile Ala Pro Ala Arg Asn Ala Ala Arg Gly Glu Thr Ala Ile Gly 210 215 220 Ile Gly Phe Leu His Asp Tyr Ser Leu Glu Lys Glu Gln Gly Ala Pro 225 230 235 240 Leu Glu Leu Ile Ser Pro Cys Glu Gly Thr Gly Tyr Glu Ile Gly Gly 245 250 255 Val Ser Ile Leu Lys Gly Ala Arg Asn Leu Asp Asn Ala Lys Leu Phe 260 265 270 Val Asp Trp Val Leu Ser Lys Glu Ala Gln Glu Leu Ala Trp Lys Lys 275 280 285 Gly Lys Ser Tyr Gln Ile Leu Thr Asn Thr Thr Ala Glu Thr Ser Pro 290 295 300 Asn Ser Leu Lys Leu Asp Asp Leu Lys Leu Ile Asn Tyr Asp Met Asp 305 310 315 320 Lys Tyr Gly Ser Thr Asp Val Arg Lys Ala Leu Ile Asn Lys Trp Val 325 330 335 Ser Glu Val Lys Met Gly Lys * 340 <210> 1363 <211> 435 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4301..5605) <400> 1363 Met His Ala Arg Ser Ala Arg Glu Ile Asn Gln Cys Tyr Arg Thr Leu 1 5 10 15 Arg Pro Arg Leu Leu Met Cys Met Ile Ile Gly Tyr Ala Ala Phe Tyr 20 25 30 Leu Thr Arg Lys Ser Val Asn Tyr Val Leu Pro Ala Leu Gln Thr Asp 35 40 45 Leu Gly Leu Asp Lys Gly Asp Ile Gly Leu Leu Gly Ser Leu Phe Tyr 50 55 60 Leu Ser Tyr Gly Leu Ser Lys Phe Thr Ala Gly Leu Trp His Asp Ser 65 70 75 80 His Gly Gln Arg Gly Phe Met Gly Val Gly Leu Phe Ala Thr Gly Leu 85 90 95 Leu Asn Val Val Phe Ala Phe Gly Glu Ser Leu Thr Leu Leu Leu Val 100 105 110 Val Trp Thr Leu Asn Gly Phe Phe Gln Gly Trp Gly Trp Pro Pro Cys 115 120 125 Ala Arg Leu Leu Thr His Trp Tyr Ser Arg Asn Glu Arg Gly Phe Trp 130 135 140 Trp Gly Cys Trp Asn Met Ser Ile Asn Ile Gly Gly Ala Ile Ile Pro 145 150 155 160 Leu Ile Ser Ala Phe Ala Ala His Trp Trp Gly Trp Gln Ala Ala Met 165 170 175 Leu Thr Pro Gly Ile Ile Ser Met Ala Leu Gly Ile Trp Leu Thr Leu 180 185 190 Gln Leu Lys Gly Thr Pro Gln Glu Glu Gly Leu Pro Thr Val Gly His 195 200 205 Trp Arg His Asp Pro Leu Glu Leu Arg Gln Glu Gln Gln Ser Pro Pro 210 215 220 Met Gly Leu Trp Gln Met Leu Arg Thr Thr Met Leu Gln Asn Pro Leu 225 230 235 240 Ile Trp Leu Leu Gly Val Ser Tyr Val Leu Val Tyr Val Ile Arg Ile 245 250 255 Ala Leu Asn Asp Trp Gly Asn Ile Trp Leu Thr Glu Ser His Gly Val 260 265 270 Asn Leu Leu Ser Ala Asn Ala Thr Val Met Leu Phe Glu Val Gly Gly 275 280 285 Leu Leu Gly Ala Leu Phe Ala Gly Trp Gly Ser Asp Leu Leu Phe Ser 290 295 300 Gly Gln Arg Ala Pro Met Ile Leu Leu Phe Thr Leu Gly Leu Met Val 305 310 315 320 Ser Val Ala Ala Leu Trp Leu Ala Pro Val His His Tyr Ala Leu Leu 325 330 335 Ala Val Cys Phe Phe Thr Val Gly Phe Phe Val Phe Gly Pro Gln Met 340 345 350 Leu Ile Gly Leu Ala Ala Val Glu Cys Gly His Lys Ala Ala Ala Gly 355 360 365 Ser Ile Thr Gly Phe Leu Gly Leu Phe Ala Tyr Leu Gly Ala Ala Leu 370 375 380 Ala Gly Trp Pro Leu Ser Leu Val Ile Glu Arg Tyr Gly Trp Pro Gly 385 390 395 400 Met Phe Ser Leu Leu Ser Val Ala Ala Val Leu Met Gly Leu Leu Leu 405 410 415 Met Pro Leu Leu Met Ala Gly Ile Thr Thr Thr His Ala Arg Arg Ile 420 425 430 Lys Gln * <210> 1364 <211> 514 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5690..7231) <400> 1364 Met Ser Arg Asn Leu Arg His Trp Val Ile Leu Leu Phe Ile Val Leu 1 5 10 15 Ala Trp Gly Thr Gly Trp Leu Met Leu Trp Thr Leu Ser Phe Tyr Leu 20 25 30 Thr Asn Asn Gly Gln Gln Ala Val Leu Phe Leu Pro Gln Gly Val Tyr 35 40 45 Leu Ala Leu Val Ile Leu Leu Ser Arg Arg Tyr Trp Pro Ala Leu Val 50 55 60 Leu Pro Pro Leu Leu Met Met Phe Trp Leu His Ser Glu Gln Leu Leu 65 70 75 80 Asn Gly Tyr Leu Met Leu Ala Thr Pro Val Ile Ser Leu Phe Pro Ala 85 90 95 Leu Leu Ala Gln Asn Phe Trp His Arg Phe Pro Leu Tyr Trp Gln Arg 100 105 110 Leu Thr Leu Leu Leu Ala Thr Val Thr Ala Ala Ser Leu Leu Asn Thr 115 120 125 Ala Leu Leu Ser Pro Phe Met Ser Gly Pro Ile Met Leu Pro Gly Leu 130 135 140 Thr Ser Phe Thr Gly Gly Val Leu Leu Thr Pro Phe Val Tyr Leu Ile 145 150 155 160 Phe Glu Phe Leu Arg Gln Gln His Arg Tyr Gln Leu Leu Gly Leu Asp 165 170 175 Thr His Asn Pro Pro Leu Arg Thr Ser Leu Ile Ile Trp Cys Ser Leu 180 185 190 Phe Phe Ile Ile Gly Ile Gly Thr Gln Met Val Leu Ser Pro Glu Ile 195 200 205 Glu Arg Leu Leu Leu Ile Val Val Phe Leu Pro Asn Val Val Met Ala 210 215 220 Trp Lys Phe Gly Trp Gln Gly Gly Val Leu Ser Gly Leu Leu Gly Ser 225 230 235 240 Met Met Ile Thr Ile Ala Arg Gln Ile Gly Val Gly Phe Ser Asn Leu 245 250 255 Val Glu Leu Glu Ile Phe Leu Ala Thr Gln Ala Leu Leu Gly Ile Gly 260 265 270 Leu Gly Ile Ala Ile Ser Arg Gln Gln His Leu Ala Leu Asn Leu His 275 280 285 His Tyr Arg Gln Arg Leu Glu Ala Glu Leu Ala Ala Arg Arg Ala Leu 290 295 300 Ala Glu Lys Leu Ile His Thr Glu Glu Asp Thr Arg Lys Asn Leu Ala 305 310 315 320 Arg Glu Leu His Asp Glu Ile Gly Gln Asn Ile Thr Ala Ile Gln Ile 325 330 335 Gln Ser Gln Leu Val Lys Arg Ala Arg Asp Pro Ala Gln Ile Gln Ser 340 345 350 Ala Ala Ser Gln Ile Asn Glu Leu Ala Arg Arg Ile His Leu Ser Thr 355 360 365 Arg Gln Leu Leu Arg Gln Leu Arg Pro Pro Ala Leu Asp Glu Leu Thr 370 375 380 Phe Arg Glu Ala Leu Leu His Leu Ile Asn Glu Phe Ala Phe Ser Glu 385 390 395 400 Arg Gly Ile His Cys Gln Phe Ala Tyr Gln Leu Asn Ser Thr Pro Glu 405 410 415 Asn Glu Thr Val Arg Phe Thr Leu Tyr Arg Leu Leu Gln Glu Leu Leu 420 425 430 Asn Asn Ile Cys Lys His Ala Glu Ala Ser Glu Val Thr Ile Ile Leu 435 440 445 Arg Gln Gln Gly Glu Val Leu His Leu Glu Val Ser Asp Asn Gly Val 450 455 460 Gly Ile Ala Ser Gly Lys Met Ala Gly Phe Gly Ile Gln Gly Met Arg 465 470 475 480 Glu Arg Val Ser Ala Leu Gly Gly Asp Leu Thr Leu Glu Lys Gln His 485 490 495 Gly Thr Arg Val Ile Val Asn Leu Pro Thr Phe Leu Gln Gln Ile Ala 500 505 510 Gly * <210> 1365 <211> 210 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(7231..7860) <400> 1365 Met Ile Arg Val Val Leu Val Asp Asp His Val Val Val Arg Ser Gly 1 5 10 15 Phe Ala Gln Leu Leu Ser Leu Glu Asp Asp Leu Glu Val Ile Gly Gln 20 25 30 Tyr Ser Ser Ala Ala Gln Ala Trp Ser Ala Leu Ile Arg Asp Asp Val 35 40 45 Asn Val Ala Val Ile Asp Ile Ala Met Pro Asp Glu Asn Gly Leu Ser 50 55 60 Leu Leu Lys Arg Leu Arg Ala Gln Lys Pro Gln Phe Arg Ala Ile Ile 65 70 75 80 Leu Ser Ile Tyr Asp Ala Pro Thr Phe Val Gln Ser Ala Leu Asp Ala 85 90 95 Gly Ala Ser Gly Tyr Leu Thr Lys Arg Cys Gly Pro Glu Glu Leu Val 100 105 110 Gln Ala Val Arg Ser Val Gly Leu Gly Gly His Tyr Leu Cys Ala Asp 115 120 125 Ala Ile Arg Ala Leu Arg Gly Gly Gly Gln Pro Ala Gln Ala Leu Glu 130 135 140 Ile Leu Thr Pro Arg Glu Arg Glu Val Phe Glu Leu Leu Val Lys Gly 145 150 155 160 Asp Ser Val Lys Glu Ile Ala Phe Lys Leu Glu Leu Ser His Lys Thr 165 170 175 Val His Val His Arg Ala Asn Val Leu Gly Lys Leu Asn Cys His Ser 180 185 190 Thr Ile Glu Leu Val His Phe Ala Leu Asp His His Leu Leu Ala Gly 195 200 205 His * <210> 1366 <211> 8099 <212> DNA <213> Escherichia coli O157:H7 <400> 1366 agtagagtgt cgttctacaa gtatgtctct tgcagatttg ccagctcaaa ccgtttttca 60 aaatttaaat cttgaaataa taaccaataa gttgacatcg gagataagat gacctcaaca 120 ttatttttct ctctcgagaa aaaaaactgg atagcgtact ggaacagagc tctcgtattc 180 ttattcatta ccacctattt tttgggtggg attacaaggt ataaacatct tattgttatt 240 cttatgacaa taacgacaat cgtctatctc tgcaaacggc caaaacacta tctctcacta 300 tttaaaacat ttctttttgg tagtgttgcc atattaacta ttgctgcatt gctgtcactt 360 cttcaatccc ctgatgcagg tgctagcatg aaggaaattt tcaaagctat tattgagaat 420 actttactat gcacaatagc aataccgatc atattgagag acgagaaaag agaagatgtc 480 gaaaaaatcg ttttcttctc atttattagt gcgttgggct tacgctgttt ttctgaattg 540 attacctatt ataaggacta tcaacaaggg ataatgccat tcgcagatta tagacaccgt 600 agcatttctg actcgatggt ctttttattc cctgcattgt taaatctctg gcttatcaaa 660 tcagcaaaat accgcatttc ttttgtggtt ctaagcgtta tttttatttt tctgatatta 720 ggaactttat ccagaggggc ctggctttcc gtgttagtca ttggattaat atggattctg 780 atgtttaaac aatggaagtt actattagta ggagtaatgg ttgccatcat tgcattgtcg 840 gttattttca cacataagga gatgaccgca aagctaacgt ataaacttca acaaactaat 900 agttcttatc gctatgcaaa tggtactcaa ggcagcgcac tcgatctaat attagaaaat 960 cctgttattg gttatggtta cggtaacgtt gcatataaag atgtctataa taaacgtgtc 1020 attgattatc cagaatggac ctttagacaa tcaatagggc cacataattt tgcgctattc 1080 atctggtttg gcactggttt attagggctg gtaagtctta tgatgctata ctgtgcaata 1140 ttgaaagagt gtataaaaaa tggcgtcaag aataaatatc gctcaccata taatgcatat 1200 tatataatct tactatcttt tataggttat tttgttatcc gtggaaacgt agaacaaatt 1260 gaaccaaatt tattaggcgt ttacgccggc ttattattag cgatgaaaaa caagtaaaaa 1320 ataaaaaagg ctgcataatg cggccttttt atttattcaa accaattatg aataacctct 1380 tcgaatcttt gagttacgcc atcccaactg tagtgatcaa acacaaagtc ctgaccttgc 1440 tttgcaactg ctgttaattc aggattcgct aacgttttta aaatatcgct gcttatggag 1500 tctgcagtca taggttcttt taaatggaat cccgtagtat tttctttgac aaattccgtc 1560 atccccccac gcgtactcac taaaacaggc ttaccagcac ccatagcttc aattgccacc 1620 atgcaaaatg gttcctggaa ctgggaagga atgacgacta aatctgccag tgggtaataa 1680 caatgcatct tttcaggcgg tatgcttcct aacataatgc aacgatcctt caaacgtttt 1740 gcaatttccc tgacattgcg ttgatatgca cctttgtcac ttttactcat ttctgtataa 1800 tcaccaatca caactaattt taaatttttg tgagcagcgg ccaatttttc gaatgattgc 1860 atcaacagca atatgccttt gtcagggacg atacgcccag cataaaaaat aattttctct 1920 tcaggggaga tattaagttc gcttctagtg atcggctgaa aattagattg ataggtttct 1980 aaatcaattc catttggtac aatctcaata tctgcatttg ctaaataaga ttggtaatac 2040 tttttcaagt ataaactagg cactatcatt ttaacatttt gctcaagcaa ttttggttca 2100 aatgcattat gcatatgtat aaccactctt gcctgaggag ctcgcttacg aatttgagtg 2160 tatagcttca tgctattatg aactacaata acactttctt tcgttatagg aaaatcatgt 2220 gcaatattca atattctctg tgaatatgga agaggatcaa gtcttgtcca tttttgaaat 2280 aaccgcttat atatgcgact gaatccaacc ctatgaatac tacaattatc attaacaaag 2340 gtgtaatttg agtatcctgg atttttgata caaacaatac gatttggaaa attggtacgc 2400 tgagcaacct gatacatcca cgtttcaaca gcagccgctc cgcgaggagg aattgaaaaa 2460 ataggagtaa ccgtaaatat tattttatca accatctcgt atattaacct ttcataacat 2520 tatatttaat tgctgtaaaa acaccatcga gaaatttttt ctggtaaagc aagtgtttat 2580 atttttcttt gtactcatgt tttttaacag cttttttata aggtatattt ctccatggtg 2640 atatattata aatattacga aaataatctg cagaggcgta gttcgcccaa tcatgccatg 2700 gcttagttat accagtataa tgtatgaaga cagtgtcatc attaataaac cgggtgtaat 2760 attcactatt tttttcttca aattctgact ttatagtata aatacaatta tattttctcg 2820 gtaatatttt agcatgatgt agaaacatta agtttaaaat atcttgatcc gggtacttta 2880 atttttttat aattgactca tctgataata gatcaaagaa tttttccgtt agtctttgtt 2940 ttaaccattc ccgtaaatta atatacatta caccagagtt aaaatagcta ccgttaaaat 3000 cctcattaca caaacgctca gcgcttttac tttgcatagc atctacatca attaccactg 3060 ccccatattc atctttaaac tctaatgcta ttaactcgtt caatgaaccc ttacagacga 3120 tatcagcatc aagatataat aatgaatcca atcgcgcaga aaaataatca aatgaaagca 3180 aacgataata aatagatact ggccagatat ttgattgagg tagcgccttc aatggctcag 3240 aatcaatatg atataattta attactgttt gatacttcgt tgctaattgt gataataatt 3300 caatatactc tttgtctaag taatcagcga ttatgtgaaa ggtaaatttg ttttgtttat 3360 tattttcaag aattgaagca attgaaatcg cagccccaac ctggtagttc tcatcaatac 3420 cccatgagac attaaacgtt tcccgttcat caagtttaac ggggcgcttg tccagttcaa 3480 ttatatcttt aaattgagta agatgtttaa aatccaattt aattaccctt cattataatc 3540 attatttgct cttcaatcct agtttgactt ttacatccct gattactttt ttaattttct 3600 ttttgaatat aagatatgta tagccaaagt ctttcaattc attttttata ttatagtgcc 3660 gttcaagatc aatgcgatct tttgctttta aaacagcggt tgttttttta cctgaaaggt 3720 caattagtct taaacctttt tcggatacta taaaatttcc cttatgagga tcgccagaca 3780 ccattccatg ctgatgcaac tcttttatcg attctgataa ttgatccttc agatcttcag 3840 aaatttccaa atactcattt aacccgacac cttcaatata ctcaatgagc ataatataat 3900 aatgagcgaa atttaatgtt ttacgttcag ctagcaaaaa atagtcatta attgattgga 3960 tgccttcacc acgtacccga tcggtttgat aaattaaatt ttcataataa tcttttttta 4020 tgcaagattt taagaaacgt tcggtcattt tatgctttgg cgcataaact ttaagtacaa 4080 gaggtccacg agcagtgtca ataagaatga ctttagtatc atcaatagaa cgaaaaactt 4140 ttaatgtttt aaccctgcaa gttaaaaagt catttagaac ttgctcataa aagggatcat 4200 tatcttttat gaaaactttc accccattta tcgttttatt atatatcata atgaattatt 4260 ttaaccttaa atctttagaa gcatttttct ttataatact ttaaataatt aaaaatgcct 4320 gccatataat gcttttgttt aaatttatgt tttgcacaat accgatactg attgctattt 4380 acaggtttaa gtaaatcttc tttactccac ggagaagctg ctttggcgat caaaaaacta 4440 cgtgacaccg gatagtcagc ccactcatgc caaggttttg taggtcccac atagtgtata 4500 aacacggtgt catcattgac tggattatca actttgtctt ttaattcata gttaatacta 4560 tatcgggtat tatatttctc cgaaataaac ttcactttac cattcaataa tacattcagt 4620 acatcttgat caaggtgggt gattttactt acccaatctg ggtcacgcaa catttcaata 4680 gcttttgacg aaatgttatt tagattccac tcatcaatat ttatcagtaa aaaaccagca 4740 ttgaaatatc cagaagctaa ctgtggtgta gttaataccg aggctcgatt ttgccaccat 4800 tcaacatctc tttcagctac aactgcggca atttcattag tagaaaattg ataatctaag 4860 agttctttaa tactaccctt gcaagcaata tctgcatcaa gatatagtat tttttcatgt 4920 ttatgataga aataatctgc aattataaat cgaaaatatg ttgcgtaagt ccagtttttc 4980 gtgcttggta atgacttcag cttatcacaa ttgataacat aaatattaat tcttgaatta 5040 tattgttttg ctaaatcaga aaaatataat ttgtctttat cactgatata atctgtgaaa 5100 acatgaaatt cacaagagat ttctctattg tttaatagaa tagatgcgat ggctacacca 5160 catccaaaaa gaaaatttct gtcaatacca aatgctatat caagagtatt tttagatctt 5220 atattttgat aatgaaaatt atactcaaaa aggatgatgt cactatcatt gagttgagac 5280 atatttattc tgtatccaaa attttggcaa aaataagtta cgggttacaa cgattttcga 5340 atcgttcttt ccctgatttt tgtggctttt gcttctgctt gcgacagcag tccttgttcc 5400 tgcttgagaa tgtctttaag cggggcggca aaatacactt tcataaaccg ccagatatcc 5460 cgctgagtca ggccgatatt catcgaagaa aaataaagcc caataagatc tttatcccgc 5520 caacgacgtg gaacgcgcgt gcgaagctgc gcccggtgca ggtcaattac cgaaattttt 5580 aactcctctt ccttaccgga aaaaggcaag tgcagcagga aatgacagat ataacagtca 5640 cggtggttaa tgcccgcagc atgcatatcg tgcaccatcg tcgcgacacg cttaataagc 5700 atacgcttta cgcgaacatc tggagggtta gtcgcccagt cagcacagta atcttcaaga 5760 cttatggttg gtgtcagatc ttcggtaata ataaatgaag ttctggtcag cggattcatg 5820 cctttttcgc caaatgccac cccatacata gtatcaacgc cgacatcccg cagtcgatga 5880 atcgcattcc attcgcggtc tgcgcctaat actggcatcc gcaatgagag taaatttttg 5940 attatctctt tcagggtcgt gccgcgatgc catttgagaa aatagctttt gcccgccatt 6000 tcaaatcgca gagtgcggcg agtttccagt tcacgaaaaa cctcaccctg caaggtttta 6060 acttcctcaa aaggatcttt accgcgccat aacgtggcaa acggctcttt aagttcaacc 6120 atccagacca cccgttatga tatccgccgc tttctctggc agactgtata aatcttgtgt 6180 atcagcataa tgtcgcgcat tttccgccca ggcctggcgc aatgaagatt gcgttaacgc 6240 tttgcgtaaa atctcattca atgtttcctg gcggaatggc tcagcaatag cctcgccgca 6300 attggcgtcg acaatataat gcgcatagcc acaaacggct gttgttagta ccggtaatcc 6360 tgcagtaatc gcttccagta gcacaattcc cgctgcttcc tggtaggcag gatgcagtaa 6420 taaatccgcc gccgccatta attccgagac atcgttgcgc cccgagaaga agtgaacatt 6480 actgcgcacg ccgcgttttt ctgccagcgc ctcaaatttt cgcggtttat cctgtccaac 6540 aacatatagc aatgtgttgt ggcgcagcga atccggtaac gaagcaagtg cttcaatgga 6600 acgatcgaca cctttacgcg tgaagtctga accgacctgc aacaataaat attgttgttc 6660 ggttattcca ttcttcttac ggaagatttc acggctatta gctggctgct ggctatattt 6720 acgatcagga taaatccccg gtggtagaat atgaaaacgc tccgcttcag tctgataatg 6780 tttctggaaa tcggcgattt gcttatctgt cagcatcagc agctgtgtcg gcttgccctg 6840 ttcgaaggtt gcccgctcaa aggcggcata atggcgataa cgtgacgtca ggtgatagaa 6900 aaagcctttt tcctgcgcga ctttctcggc ataacaaaca tcagcggcat aataaacgtc 6960 cagccccggc attttgttga atccaacgac tttatcgacg ggatgttcgc gtaaatgttt 7020 ttgcacccag gcaaaatact ccgcattgcg cccgtgattg gtatgcgatt taaccggcac 7080 tttgatcagt tcaaatacat cagggcattc gccttcccac gactgggtat aaacccgaac 7140 atgatgacct cgggcggcga ctgtctgagc aatacgcata aaatcgcgct gcaaaccgcc 7200 aaagggaaaa tatttatata aacaaaaagc aacgatcata acgacgtacc tgtcgtggag 7260 gagggcagta atttatcgac agcagcaatg acatctgccg ccggaataac cgaaagatac 7320 atctcatttc ggtcacgctg atcgcgcgtt ggcatttccc ggtaatctcc cgcccagaat 7380 tgaatcatgt tatttgacca aggacgccag aaaatatggt ctgtcgcacc aaacagcgat 7440 atcagcggcg tattaactgc agcggcaata tgcgccggtg cggaatcaac gccaataaac 7500 agctgcgcat gatcgattaa cgcaccaagt tccgggaagg tcacctttcc agccagcgcc 7560 gttactggtg gcgtctggca tccttgcgca atttcattga cgcaggccag atcgtcttta 7620 tctgggccgg acgtcagaac gacttcataa ccacgagcat gtaaggcatc aatcacagcg 7680 gaaaacttgg cgttgtccca gcatttgaag atttgccgcg ccgtaggttg gataaccaca 7740 taattttgtc caacaccagc gtgatcaagt tcgcgacgca tacgtttcca gcttgcaggc 7800 gggtaactca tggttgtctg cttcaccaac gaatcaagtc ccaatggtgt cagcacggat 7860 aagttacttt ccaccacatt tccaccctgc aacggcacca aatgggtgaa acttttacgc 7920 caaaaagcag actgccgatg atgataatcc tgggaaattt tcacacgggc atttaataag 7980 cgaaccagta tagcaaccat ccattgatcg gtaagattga cgataaggtc atacttattg 8040 gcacgtaata ccttgatgag atgaaaaaag ttggcaattt tttctgaggc ttttgcttt 8099 <210> 1367 <211> 403 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(109..1317) <400> 1367 Met Thr Ser Thr Leu Phe Phe Ser Leu Glu Lys Lys Asn Trp Ile Ala 1 5 10 15 Tyr Trp Asn Arg Ala Leu Val Phe Leu Phe Ile Thr Thr Tyr Phe Leu 20 25 30 Gly Gly Ile Thr Arg Tyr Lys His Leu Ile Val Ile Leu Met Thr Ile 35 40 45 Thr Thr Ile Val Tyr Leu Cys Lys Arg Pro Lys His Tyr Leu Ser Leu 50 55 60 Phe Lys Thr Phe Leu Phe Gly Ser Val Ala Ile Leu Thr Ile Ala Ala 65 70 75 80 Leu Leu Ser Leu Leu Gln Ser Pro Asp Ala Gly Ala Ser Met Lys Glu 85 90 95 Ile Phe Lys Ala Ile Ile Glu Asn Thr Leu Leu Cys Thr Ile Ala Ile 100 105 110 Pro Ile Ile Leu Arg Asp Glu Lys Arg Glu Asp Val Glu Lys Ile Val 115 120 125 Phe Phe Ser Phe Ile Ser Ala Leu Gly Leu Arg Cys Phe Ser Glu Leu 130 135 140 Ile Thr Tyr Tyr Lys Asp Tyr Gln Gln Gly Ile Met Pro Phe Ala Asp 145 150 155 160 Tyr Arg His Arg Ser Ile Ser Asp Ser Met Val Phe Leu Phe Pro Ala 165 170 175 Leu Leu Asn Leu Trp Leu Ile Lys Ser Ala Lys Tyr Arg Ile Ser Phe 180 185 190 Val Val Leu Ser Val Ile Phe Ile Phe Leu Ile Leu Gly Thr Leu Ser 195 200 205 Arg Gly Ala Trp Leu Ser Val Leu Val Ile Gly Leu Ile Trp Ile Leu 210 215 220 Met Phe Lys Gln Trp Lys Leu Leu Leu Val Gly Val Met Val Ala Ile 225 230 235 240 Ile Ala Leu Ser Val Ile Phe Thr His Lys Glu Met Thr Ala Lys Leu 245 250 255 Thr Tyr Lys Leu Gln Gln Thr Asn Ser Ser Tyr Arg Tyr Ala Asn Gly 260 265 270 Thr Gln Gly Ser Ala Leu Asp Leu Ile Leu Glu Asn Pro Val Ile Gly 275 280 285 Tyr Gly Tyr Gly Asn Val Ala Tyr Lys Asp Val Tyr Asn Lys Arg Val 290 295 300 Ile Asp Tyr Pro Glu Trp Thr Phe Arg Gln Ser Ile Gly Pro His Asn 305 310 315 320 Phe Ala Leu Phe Ile Trp Phe Gly Thr Gly Leu Leu Gly Leu Val Ser 325 330 335 Leu Met Met Leu Tyr Cys Ala Ile Leu Lys Glu Cys Ile Lys Asn Gly 340 345 350 Val Lys Asn Lys Tyr Arg Ser Pro Tyr Asn Ala Tyr Tyr Ile Ile Leu 355 360 365 Leu Ser Phe Ile Gly Tyr Phe Val Ile Arg Gly Asn Val Glu Gln Ile 370 375 380 Glu Pro Asn Leu Leu Gly Val Tyr Ala Gly Leu Leu Leu Ala Met Lys 385 390 395 400 Asn Lys * <210> 1368 <211> 381 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1353..2495) <400> 1368 Met Val Asp Lys Ile Ile Phe Thr Val Thr Pro Ile Phe Ser Ile Pro 1 5 10 15 Pro Arg Gly Ala Ala Ala Val Glu Thr Trp Met Tyr Gln Val Ala Gln 20 25 30 Arg Thr Asn Phe Pro Asn Arg Ile Val Cys Ile Lys Asn Pro Gly Tyr 35 40 45 Ser Asn Tyr Thr Phe Val Asn Asp Asn Cys Ser Ile His Arg Val Gly 50 55 60 Phe Ser Arg Ile Tyr Lys Arg Leu Phe Gln Lys Trp Thr Arg Leu Asp 65 70 75 80 Pro Leu Pro Tyr Ser Gln Arg Ile Leu Asn Ile Ala His Asp Phe Pro 85 90 95 Ile Thr Lys Glu Ser Val Ile Val Val His Asn Ser Met Lys Leu Tyr 100 105 110 Thr Gln Ile Arg Lys Arg Ala Pro Gln Ala Arg Val Val Ile His Met 115 120 125 His Asn Ala Phe Glu Pro Lys Leu Leu Glu Gln Asn Val Lys Met Ile 130 135 140 Val Pro Ser Leu Tyr Leu Lys Lys Tyr Tyr Gln Ser Tyr Leu Ala Asn 145 150 155 160 Ala Asp Ile Glu Ile Val Pro Asn Gly Ile Asp Leu Glu Thr Tyr Gln 165 170 175 Ser Asn Phe Gln Pro Ile Thr Arg Ser Glu Leu Asn Ile Ser Pro Glu 180 185 190 Glu Lys Ile Ile Phe Tyr Ala Gly Arg Ile Val Pro Asp Lys Gly Ile 195 200 205 Leu Leu Leu Met Gln Ser Phe Glu Lys Leu Ala Ala Ala His Lys Asn 210 215 220 Leu Lys Leu Val Val Ile Gly Asp Tyr Thr Glu Met Ser Lys Ser Asp 225 230 235 240 Lys Gly Ala Tyr Gln Arg Asn Val Arg Glu Ile Ala Lys Arg Leu Lys 245 250 255 Asp Arg Cys Ile Met Leu Gly Ser Ile Pro Pro Glu Lys Met His Cys 260 265 270 Tyr Tyr Pro Leu Ala Asp Leu Val Val Ile Pro Ser Gln Phe Gln Glu 275 280 285 Pro Phe Cys Met Val Ala Ile Glu Ala Met Gly Ala Gly Lys Pro Val 290 295 300 Leu Val Ser Thr Arg Gly Gly Met Thr Glu Phe Val Lys Glu Asn Thr 305 310 315 320 Thr Gly Phe His Leu Lys Glu Pro Met Thr Ala Asp Ser Ile Ser Ser 325 330 335 Asp Ile Leu Lys Thr Leu Ala Asn Pro Glu Leu Thr Ala Val Ala Lys 340 345 350 Gln Gly Gln Asp Phe Val Phe Asp His Tyr Ser Trp Asp Gly Val Thr 355 360 365 Gln Arg Phe Glu Glu Val Ile His Asn Trp Phe Glu * 370 375 380 <210> 1369 <211> 338 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2504..3517) <400> 1369 Leu Asp Phe Lys His Leu Thr Gln Phe Lys Asp Ile Ile Glu Leu Asp 1 5 10 15 Lys Arg Pro Val Lys Leu Asp Glu Arg Glu Thr Phe Asn Val Ser Trp 20 25 30 Gly Ile Asp Glu Asn Tyr Gln Val Gly Ala Ala Ile Ser Ile Ala Ser 35 40 45 Ile Leu Glu Asn Asn Lys Gln Asn Lys Phe Thr Phe His Ile Ile Ala 50 55 60 Asp Tyr Leu Asp Lys Glu Tyr Ile Glu Leu Leu Ser Gln Leu Ala Thr 65 70 75 80 Lys Tyr Gln Thr Val Ile Lys Leu Tyr His Ile Asp Ser Glu Pro Leu 85 90 95 Lys Ala Leu Pro Gln Ser Asn Ile Trp Pro Val Ser Ile Tyr Tyr Arg 100 105 110 Leu Leu Ser Phe Asp Tyr Phe Ser Ala Arg Leu Asp Ser Leu Leu Tyr 115 120 125 Leu Asp Ala Asp Ile Val Cys Lys Gly Ser Leu Asn Glu Leu Ile Ala 130 135 140 Leu Glu Phe Lys Asp Glu Tyr Gly Ala Val Val Ile Asp Val Asp Ala 145 150 155 160 Met Gln Ser Lys Ser Ala Glu Arg Leu Cys Asn Glu Asp Phe Asn Gly 165 170 175 Ser Tyr Phe Asn Ser Gly Val Met Tyr Ile Asn Leu Arg Glu Trp Leu 180 185 190 Lys Gln Arg Leu Thr Glu Lys Phe Phe Asp Leu Leu Ser Asp Glu Ser 195 200 205 Ile Ile Lys Lys Leu Lys Tyr Pro Asp Gln Asp Ile Leu Asn Leu Met 210 215 220 Phe Leu His His Ala Lys Ile Leu Pro Arg Lys Tyr Asn Cys Ile Tyr 225 230 235 240 Thr Ile Lys Ser Glu Phe Glu Glu Lys Asn Ser Glu Tyr Tyr Thr Arg 245 250 255 Phe Ile Asn Asp Asp Thr Val Phe Ile His Tyr Thr Gly Ile Thr Lys 260 265 270 Pro Trp His Asp Trp Ala Asn Tyr Ala Ser Ala Asp Tyr Phe Arg Asn 275 280 285 Ile Tyr Asn Ile Ser Pro Trp Arg Asn Ile Pro Tyr Lys Lys Ala Val 290 295 300 Lys Lys His Glu Tyr Lys Glu Lys Tyr Lys His Leu Leu Tyr Gln Lys 305 310 315 320 Lys Phe Leu Asp Gly Val Phe Thr Ala Ile Lys Tyr Asn Val Met Lys 325 330 335 Gly * <210> 1370 <211> 236 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3542..4249) <400> 1370 Met Ile Tyr Asn Lys Thr Ile Asn Gly Val Lys Val Phe Ile Lys Asp 1 5 10 15 Asn Asp Pro Phe Tyr Glu Gln Val Leu Asn Asp Phe Leu Thr Cys Arg 20 25 30 Val Lys Thr Leu Lys Val Phe Arg Ser Ile Asp Asp Thr Lys Val Ile 35 40 45 Leu Ile Asp Thr Ala Arg Gly Pro Leu Val Leu Lys Val Tyr Ala Pro 50 55 60 Lys His Lys Met Thr Glu Arg Phe Leu Lys Ser Cys Ile Lys Lys Asp 65 70 75 80 Tyr Tyr Glu Asn Leu Ile Tyr Gln Thr Asp Arg Val Arg Gly Glu Gly 85 90 95 Ile Gln Ser Ile Asn Asp Tyr Phe Leu Leu Ala Glu Arg Lys Thr Leu 100 105 110 Asn Phe Ala His Tyr Tyr Ile Met Leu Ile Glu Tyr Ile Glu Gly Val 115 120 125 Gly Leu Asn Glu Tyr Leu Glu Ile Ser Glu Asp Leu Lys Asp Gln Leu 130 135 140 Ser Glu Ser Ile Lys Glu Leu His Gln His Gly Met Val Ser Gly Asp 145 150 155 160 Pro His Lys Gly Asn Phe Ile Val Ser Glu Lys Gly Leu Arg Leu Ile 165 170 175 Asp Leu Ser Gly Lys Lys Thr Thr Ala Val Leu Lys Ala Lys Asp Arg 180 185 190 Ile Asp Leu Glu Arg His Tyr Asn Ile Lys Asn Glu Leu Lys Asp Phe 195 200 205 Gly Tyr Thr Tyr Leu Ile Phe Lys Lys Lys Ile Lys Lys Val Ile Arg 210 215 220 Asp Val Lys Val Lys Leu Gly Leu Lys Ser Lys * 225 230 235 <210> 1371 <211> 336 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4275..5282) <400> 1371 Met Ser Gln Leu Asn Asp Ser Asp Ile Ile Leu Phe Glu Tyr Asn Phe 1 5 10 15 His Tyr Gln Asn Ile Arg Ser Lys Asn Thr Leu Asp Ile Ala Phe Gly 20 25 30 Ile Asp Arg Asn Phe Leu Phe Gly Cys Gly Val Ala Ile Ala Ser Ile 35 40 45 Leu Leu Asn Asn Arg Glu Ile Ser Cys Glu Phe His Val Phe Thr Asp 50 55 60 Tyr Ile Ser Asp Lys Asp Lys Leu Tyr Phe Ser Asp Leu Ala Lys Gln 65 70 75 80 Tyr Asn Ser Arg Ile Asn Ile Tyr Val Ile Asn Cys Asp Lys Leu Lys 85 90 95 Ser Leu Pro Ser Thr Lys Asn Trp Thr Tyr Ala Thr Tyr Phe Arg Phe 100 105 110 Ile Ile Ala Asp Tyr Phe Tyr His Lys His Glu Lys Ile Leu Tyr Leu 115 120 125 Asp Ala Asp Ile Ala Cys Lys Gly Ser Ile Lys Glu Leu Leu Asp Tyr 130 135 140 Gln Phe Ser Thr Asn Glu Ile Ala Ala Val Val Ala Glu Arg Asp Val 145 150 155 160 Glu Trp Trp Gln Asn Arg Ala Ser Val Leu Thr Thr Pro Gln Leu Ala 165 170 175 Ser Gly Tyr Phe Asn Ala Gly Phe Leu Leu Ile Asn Ile Asp Glu Trp 180 185 190 Asn Leu Asn Asn Ile Ser Ser Lys Ala Ile Glu Met Leu Arg Asp Pro 195 200 205 Asp Trp Val Ser Lys Ile Thr His Leu Asp Gln Asp Val Leu Asn Val 210 215 220 Leu Leu Asn Gly Lys Val Lys Phe Ile Ser Glu Lys Tyr Asn Thr Arg 225 230 235 240 Tyr Ser Ile Asn Tyr Glu Leu Lys Asp Lys Val Asp Asn Pro Val Asn 245 250 255 Asp Asp Thr Val Phe Ile His Tyr Val Gly Pro Thr Lys Pro Trp His 260 265 270 Glu Trp Ala Asp Tyr Pro Val Ser Arg Ser Phe Leu Ile Ala Lys Ala 275 280 285 Ala Ser Pro Trp Ser Lys Glu Asp Leu Leu Lys Pro Val Asn Ser Asn 290 295 300 Gln Tyr Arg Tyr Cys Ala Lys His Lys Phe Lys Gln Lys His Tyr Met 305 310 315 320 Ala Gly Ile Phe Asn Tyr Leu Lys Tyr Tyr Lys Glu Lys Cys Phe * 325 330 335 <210> 1372 <211> 269 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5325..6131) <400> 1372 Val Val Trp Met Val Glu Leu Lys Glu Pro Phe Ala Thr Leu Trp Arg 1 5 10 15 Gly Lys Asp Pro Phe Glu Glu Val Lys Thr Leu Gln Gly Glu Val Phe 20 25 30 Arg Glu Leu Glu Thr Arg Arg Thr Leu Arg Phe Glu Met Ala Gly Lys 35 40 45 Ser Tyr Phe Leu Lys Trp His Arg Gly Thr Thr Leu Lys Glu Ile Ile 50 55 60 Lys Asn Leu Leu Ser Leu Arg Met Pro Val Leu Gly Ala Asp Arg Glu 65 70 75 80 Trp Asn Ala Ile His Arg Leu Arg Asp Val Gly Val Asp Thr Met Tyr 85 90 95 Gly Val Ala Phe Gly Glu Lys Gly Met Asn Pro Leu Thr Arg Thr Ser 100 105 110 Phe Ile Ile Thr Glu Asp Leu Thr Pro Thr Ile Ser Leu Glu Asp Tyr 115 120 125 Cys Ala Asp Trp Ala Thr Asn Pro Pro Asp Val Arg Val Lys Arg Met 130 135 140 Leu Ile Lys Arg Val Ala Thr Met Val His Asp Met His Ala Ala Gly 145 150 155 160 Ile Asn His Arg Asp Cys Tyr Ile Cys His Phe Leu Leu His Leu Pro 165 170 175 Phe Ser Gly Lys Glu Glu Glu Leu Lys Ile Ser Val Ile Asp Leu His 180 185 190 Arg Ala Gln Leu Arg Thr Arg Val Pro Arg Arg Trp Arg Asp Lys Asp 195 200 205 Leu Ile Gly Leu Tyr Phe Ser Ser Met Asn Ile Gly Leu Thr Gln Arg 210 215 220 Asp Ile Trp Arg Phe Met Lys Val Tyr Phe Ala Ala Pro Leu Lys Asp 225 230 235 240 Ile Leu Lys Gln Glu Gln Gly Leu Leu Ser Gln Ala Glu Ala Lys Ala 245 250 255 Thr Lys Ile Arg Glu Arg Thr Ile Arg Lys Ser Leu * 260 265 <210> 1373 <211> 375 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6115..7239) <400> 1373 Met Ile Val Ala Phe Cys Leu Tyr Lys Tyr Phe Pro Phe Gly Gly Leu 1 5 10 15 Gln Arg Asp Phe Met Arg Ile Ala Gln Thr Val Ala Ala Arg Gly His 20 25 30 His Val Arg Val Tyr Thr Gln Ser Trp Glu Gly Glu Cys Pro Asp Val 35 40 45 Phe Glu Leu Ile Lys Val Pro Val Lys Ser His Thr Asn His Gly Arg 50 55 60 Asn Ala Glu Tyr Phe Ala Trp Val Gln Lys His Leu Arg Glu His Pro 65 70 75 80 Val Asp Lys Val Val Gly Phe Asn Lys Met Pro Gly Leu Asp Val Tyr 85 90 95 Tyr Ala Ala Asp Val Cys Tyr Ala Glu Lys Val Ala Gln Glu Lys Gly 100 105 110 Phe Phe Tyr His Leu Thr Ser Arg Tyr Arg His Tyr Ala Ala Phe Glu 115 120 125 Arg Ala Thr Phe Glu Gln Gly Lys Pro Thr Gln Leu Leu Met Leu Thr 130 135 140 Asp Lys Gln Ile Ala Asp Phe Gln Lys His Tyr Gln Thr Glu Ala Glu 145 150 155 160 Arg Phe His Ile Leu Pro Pro Gly Ile Tyr Pro Asp Arg Lys Tyr Ser 165 170 175 Gln Gln Pro Ala Asn Ser Arg Glu Ile Phe Arg Lys Lys Asn Gly Ile 180 185 190 Thr Glu Gln Gln Tyr Leu Leu Leu Gln Val Gly Ser Asp Phe Thr Arg 195 200 205 Lys Gly Val Asp Arg Ser Ile Glu Ala Leu Ala Ser Leu Pro Asp Ser 210 215 220 Leu Arg His Asn Thr Leu Leu Tyr Val Val Gly Gln Asp Lys Pro Arg 225 230 235 240 Lys Phe Glu Ala Leu Ala Glu Lys Arg Gly Val Arg Ser Asn Val His 245 250 255 Phe Phe Ser Gly Arg Asn Asp Val Ser Glu Leu Met Ala Ala Ala Asp 260 265 270 Leu Leu Leu His Pro Ala Tyr Gln Glu Ala Ala Gly Ile Val Leu Leu 275 280 285 Glu Ala Ile Thr Ala Gly Leu Pro Val Leu Thr Thr Ala Val Cys Gly 290 295 300 Tyr Ala His Tyr Ile Val Asp Ala Asn Cys Gly Glu Ala Ile Ala Glu 305 310 315 320 Pro Phe Arg Gln Glu Thr Leu Asn Glu Ile Leu Arg Lys Ala Leu Thr 325 330 335 Gln Ser Ser Leu Arg Gln Ala Trp Ala Glu Asn Ala Arg His Tyr Ala 340 345 350 Asp Thr Gln Asp Leu Tyr Ser Leu Pro Glu Lys Ala Ala Asp Ile Ile 355 360 365 Thr Gly Gly Leu Asp Gly * 370 <210> 1374 <211> 7886 <212> DNA <213> Escherichia coli O157:H7 <400> 1374 gctttctgta ccggagagaa gctgcggtac agagcatttt gcgttatcta ctcttgacgc 60 ctgcaagggg taggttgggg aaatatctta tagaatctga ctatgaaact attcgtatta 120 gctccgataa gtttgatgat gaaaacagaa ctggcgacaa caagtagcag cctttctgat 180 gaattgaccc caacttaata ttgtcaacta tcttcacaga atctccacaa tctcttcatt 240 atcagaatat gcaccatgaa taagataaaa atactttcca ttactttgga gaaacgtata 300 atcagcaaaa atgagaacga tcattctcac caagtgatag gccaggagac agaaatgacc 360 agcaagctgg aaatacgcca caaacagcgt caggatgaaa tcattaacgc cgcccgtcgg 420 tgttttcgtc gctgcgggtt tcatgccgcc agtatgtcgc aaattgccag cgaagctcag 480 cttagcgtgg gtcagatata tcgttacttc gccaacaaag acgccattat tgaagagatg 540 gttcgccgta tcatcgactt tcgtattgcc caaatggaca ttgacgcgcg taccgatcac 600 ttcccggaag tccttgcctt gcgtaaatcc ttaaatgagg acgacgacgc gctgatgctg 660 gaagtggctg cagaagccac acgcaacccg cgggttatgg caatgcttga agaagctgac 720 gccagaatgt tcgctaacgg ttgtgcacat atgaaaagaa tgcatcccca tcttagcgag 780 gagcacattc gttgctgcgt tgaagtgttt gctaccatga tggaaggtac ggtttatcgt 840 cgtttaacac cgcaaaaaag cgatccacaa catctgcagg aaatatatca ggatattgtt 900 agtatgttga taaataaata agaacagaat taaccaatag cgggggatat taatccccct 960 tatttcattg cgaaattcat ttcgcgatgc gggttcgtta taactgaata tccctgacat 1020 atcctcatta attttaatga ggagggtatt tctcaccctg gagaaaataa tgaagtatat 1080 agcaacatct gtagtggcaa tgctgctctt atctggttgt gataatacgc aaagtaacaa 1140 ttcatccccg tcagaaacag aagtcggcgt tgttacagtc aaatctcaac cggtctcggt 1200 agtcagtgaa ttaaccggac gcaccagtgc tgcgctcagt gccgaagtac gtccgcaggt 1260 tgggggaatt atccagaaac gcttatttaa ggaaggtgat ctggtcaagg ctggacagcc 1320 gctctaccag attgatgcgg ccagttatca ggctgcatgg aatgaagctc gggcagcatt 1380 acaacaagca caggcactgg taaaagccga ttgccagaaa gcgcagcgtt atgcccgact 1440 ggtgaaagag aacggtgttt cacaacagga tgctgatgat gctcagtcta cctgtgcaca 1500 agataaagcc agtgtagcgg cgaaaaaagc cgcactggaa actgcgcgca ttaatcttga 1560 ctggaccacg gtaaccgcac cgatttcagg gcgcattggc atttcgtcgg taacccctgg 1620 cgcactggtg accgcgtcgc aagatacagc gttaacgact attcgtggtc tggatacaat 1680 gtatgtcgac ctcactcgct ccagtgtcga tttattacgt ctgcgtaaac agtcactggc 1740 gaccaacagt gacaccatga gcgtctcact tattctggaa gatggcacaa cctacagcga 1800 aaaagggcgt ctggaactca ccgaagtcgc tgtagatgag tctaccggtt cggtgacatt 1860 acgggcgatt ttccccaatc cacaacagca attattaccg ggaatgtttg ttcgcgctcg 1920 tgtcgatgaa ggcgtgatgg aagacgctat tctcgcgccg caacagggcg tcacgcgcga 1980 tgctaaaggc aatgcaactg cgctggtggt gaataaagac aataaagtag agcagcgaac 2040 gctcgaaacg ggagaaacat atggtgataa atggctggtg ctaaacggcc tgcacagcgg 2100 cgaccgactg attgttgaag gttctgccaa agtcacttca gggcagacgg tcaaggctgt 2160 tgaagttcag gctaatggag gcaacgcctg atgttttcgc gcttttttgt tcgccgcccg 2220 gtctttgcct gggttatcgc cattttgatt atgttggcgg ggattctggc tattcgcaca 2280 ttgcccgtcg cgcaatatcc tgacgttgcg ccaccgacca ttaaaatttc agccacttat 2340 actggtgctt ctgccgaaac gctggagaac agcgtgactc aggtcatcga gcaacaactc 2400 actgggcttg ataatttact ctatttcagc tcaaccagca gctctgatgg ttcggtcagt 2460 attaatgtga cctttgaaca aggtaccgat ccagatactg cacaggtgca gaataaaatt 2520 cagcaggcgg agtcgcgcct acccagcgaa gtgcagcaaa cgggtgttac ggtggagaaa 2580 tcacaaagca actttttgct gattgctgcc gtgtatgaca ccactgacaa agcctccagt 2640 tcggatatcg ccgactggtt ggttagtaac gttcaggacc cgctggcgcg tgttgaaggt 2700 gtggggagtc tgcaagtctt tggcgcggaa tacgctatgc gcatctggct tgacccggcc 2760 aaactggcgt cttactcgct aatgccttca gacgtgcaaa gtgctattga agcgcaaaac 2820 gtgcaggtta ctgccgggaa aataggggca ttgccttcac cgaatactca gcaactgacc 2880 gcaacggttc gtgcgcagtc tcgcttgcag acggtggatc agttcaaaaa tattatcgtg 2940 aaaagccagt cagacagcgc agttgttcgt ataaaagatg tggctcgcgt tgagatgggc 3000 agtgaagatt ataccgctat cggcaaactt aacggtcacc cgtctgccgg ggttgctgta 3060 atgctttcgc ccggtgcgaa tgcgctgaat acggcgacgc tggtcaagga taagattgcc 3120 gaattccagc ggaacatgcc gcagggatac gacatcgctt acccgaaaga cagcactgaa 3180 tttattaaaa tctctgtaga ggacgtaatt cagacgctgt ttgaagccat cgtattggtg 3240 gtttgcgtga tgtatttatt cctgcaaaac ctgcgtgcca cactgattcc ggcgttagct 3300 gtccccgtcg ttttgctggg cacattcggc gttcttgcgt tgtttggcta ttcgattaat 3360 accctgacgt tgtttgctat ggtgctggcg atcggcttgc tggtggacga tgccattgtg 3420 gtagtggaga acgtcgaacg cattatgcgt gacaaagggt tgcccgcgcg tgaagccacg 3480 gaaaaatcaa tgggcgagat ttctggcgca ctggttgcca ttgcgctggt gttgtcagcc 3540 gtattcctgc ctatggcctt ctttggggga tctacggggg taatttatcg tcagttttcg 3600 ataaccatta tctccgcaat gctgctttcc gtggtggtgg cattgacctt gactcccgcc 3660 ctgtgcggtt ccgtcctcca gcatgttccg ccacataaaa aaggcttttt cggcgcattt 3720 gaccgctttt accgccgtac tgaagataaa tatcagcgag gcgtaattta tgtcctgcgc 3780 cgtgctgctc gaacgatggg gctttatctc gtactgggtg gtggaatggc cctgatgatg 3840 tggaaactgc cgggcagttt cttacccact gaagaccagg gcgaaatcat ggtgcagtac 3900 acgctgccgg ccggggcgac cgctgcccgt acagcagaag tgaatcgcca gattgttgac 3960 tggttcctga ttaacgagaa agcaaatacc gatgtcattt ttaccgttga tggtttcagt 4020 tttagcggca gcggacagaa caccgggatg gcgtttgttt cgttgaaaaa ctggtctcaa 4080 cgtaaagggg cagaaaacac cgcccaggct atcgccctac gggcaaccaa agagctgggc 4140 acaattcgtg atgccacggt atttgcgatg acgccgccag ccgttgatgg gctggggcaa 4200 agcaatggtt ttacgtttga attgttagct aacggtggaa ccgatcgcga aacactactg 4260 caaatgcgta atcagttgat agaaaaagcg aatcaaagtc cggagttaca ttctgttcgt 4320 gccaatgatt tgccacaaat gccgcaattg caggtagata ttgatagtaa taaagcggtg 4380 tcattagggt tgagtttgaa tgatgtcacc gacaccctgt ccagtgcgtg gggcggtact 4440 tatgtgaatg actttattga ccgtggtcgt gtgaaaaaag tctacattca gggcgacagt 4500 gaatttcgtt ccgcgccgtc agacttaggt aaatggtttg tgcgcggtag tgataacgcc 4560 atgacaccat tctctgcttt tgcgaccacc cgctggctgt atggaccgga aagactggtg 4620 cgctacaacg gttctgcagc ctatgaaatt cagggggaaa atgcgactgg ctttagttcc 4680 ggcgatgcaa tgacaaaaat ggaggaactg gcaaacagtc ttcctgcggg aacaacctgg 4740 gcctggagtg gtttgtcatt gcaggagaaa ctggccagcg gtcaggcatt gagtctgtat 4800 gcagtttcta ttctggtggt tttcctctgc cttgcagcac tgtacgaaag ctggtcagtc 4860 ccgttctcgg tcattctggt gatccctctg gggcttcttg gcgcggcgct ggcggcctgg 4920 atgcgtgatt taaacaacga tgtttacttc caggtggcgc tattaaccac tatcggcttg 4980 tcgtcgaaaa acgccattct gattgtggaa tttgctgaag cggcggttgc agagggttat 5040 tccttgagtc gtgcggcatt acgcgcggcg cagactcgtt tacgcccaat catcatgacc 5100 tcgctggcgt ttattgcggg gggtaatgcc gctggcgata gcaaccggct caggggcgaa 5160 cagccgcatc gccattggta cgggcattat tggcggtacg ctgaccgcta cgttgctggc 5220 tattttcttt gttcctctgt tttttgtact ggtgaagcgt ttgtttgccg gtaaatcgcg 5280 ccgtcaggag taagttatgt tgcgtcgttc tcttattttt ctggtgctgt tgagtgcggg 5340 atgtgtctcg ctcgatcccc actacagcac gcctgaatcc ccaatcccgg cgaccttgcc 5400 gggagcacag ggccagggaa aggcaatcag ccatgactgg cagcaggtga tccacgatcc 5460 ccgattgcag caggtggtga ctattgcact gaacagtaac cgcgatgtgc aaaaagcgat 5520 tgctgatatt gactcagcac gggcgctcta tgggcaaact aatgcgtcgt tattcccgac 5580 ggtgaatgcg gccttaagtt caacccgcag tcgttcgctg gcgaatggta cggaaaccac 5640 tgccgaggct gacggcacgg tgtccagttt tacgttagat ctgtttggtc gtaatcagag 5700 tttatctcgg gcggcgcgag aaacctggct tgccagtgaa tttacagccc agaacacccg 5760 tttaacgctg attgctgaaa tcagcaccgc ctggctgaca ctggcggccg ataacagcaa 5820 cctggccctg gcaaaagaaa cgatgaccag tgcagaaaac tcattgaaaa ttatccagcg 5880 ccagcaacag gttggcacgg cggcagcgac agatgtcagt gaggcgatga gtgtttatca 5940 gcaagcgcgc gccagcgttg ccagctatca gacacaagtg atgcaggata aaaatgcgct 6000 gaacttactg gcaggtacaa cgcttgagga aaatttgcta ccgggaacac tggaaagcct 6060 gccggaacag atgataagtc tggttcctgc gggagtgtca tctgacgttc tgctgcgtcg 6120 cccggatatc caggaagcgg aacataattt gaagagcgcc aatgccgata ttggcgcggc 6180 gcgggctaac tttttcccga cgatttcgct gactgccagc gctggtgttg gcagtgacgc 6240 attgtcgtcg ttgttcagcc acggaatgca gatctggtca tttacgccat cggtcacatt 6300 accgctgttc actggcggaa gtaatctggc gcagcttcgt tacgcagaag cacaaaagcg 6360 tggactcatt gccacctatg aaaaaaccgt tcagagagca tttaaagatg tcgctaacgc 6420 actggcgcgg cggaccacgc ttgaagagca actggatgca cagcgccagt atgttaaagc 6480 tgagcaacaa acggtcgatg ttggcttgcg tcgctatcag acgggtgttg gtgattacct 6540 gaccgtgttg acggcgcagc gcagcttgtg gagcgcacag caggagctgc tggcactgca 6600 actgactgat tttacaaacc gaatcacgct ctggcagtcg ctgggcggcg gcatgtcatc 6660 actcaagtaa ggaataatat ggctagagtc tctctttcat gggcattgat tcttggtctt 6720 ttagccggta tcggcccgat gtgtaccgat ctttatttgc cggctttgcc ggagatgtct 6780 gagcaactgg cggcaaccac gaccataacg caattaacgc tgactgcatc actgatcggt 6840 cttggcgtcg gacaactgtt atttggccct ctgagcgaca aaatagggcg taaacgtccg 6900 ttaatcttgt cgttgctatt gtttattgtt tcttccattt tgtgcgcgac aacgaacaat 6960 atttactggc tggtggtctg gcgttttatt caagggatcg cgggggcggg tggttcggtg 7020 ctctctcgtt ctattgctcg tgacaaatat cagggagtaa cgttgaccca gttttttgcg 7080 ctgttaatga cggtgaatgg cctggcaccg gtgttgtcgc cagtgctggg cgggtacatt 7140 gttagcactt ttgactggcg cactttattc tgggtaatgg ctgaaattag caccgtattg 7200 ttgctgggct gcgtgttatt tattaatgag accttgccag aaaataaaag gggctcatca 7260 ttgctattaa ccggacgaag cgtggtgcag aaccgccgtt ttatgcgctt ttgcctgatt 7320 caaagtttta tgctggcagg cttgtttgcg tatatcggct cttcgtcgtt cgtgttgcag 7380 aaggaatttg gctttagtcc aatgcaattt agcctggtgt ttggccttaa cggcatcgga 7440 cttatcattg cttcatggat cttttcgcgt ctggcgcgac ggattaatgc gatgacattg 7500 ttgcgaggtg gcctgatagc ggcaattttg tgtgcattgc tcacggtctt atgcgcatgg 7560 acacaattgc ccattccggc actggtggca ttatttttca ctattgcatt ttgtagcggc 7620 atcggcactg ttggcggggc agaggctatg agtgcagtag ggacgcagga atctggaacg 7680 gcgtctgcgt tgatggggat gagcatgttt gtcttcggcg gtatagccgc gccattgtcg 7740 ggatttggcg gagaaacact gttaaaaatg agtctggcaa ttacggtgtg ttatacactg 7800 gcattcctgg ttgctctcac cagaatcgac aatcaaaagt aatgaatacc tcatcctgag 7860 gggggttccc ctgtcaggat gaggtg 7886 <210> 1375 <211> 189 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(355..921) <400> 1375 Met Thr Ser Lys Leu Glu Ile Arg His Lys Gln Arg Gln Asp Glu Ile 1 5 10 15 Ile Asn Ala Ala Arg Arg Cys Phe Arg Arg Cys Gly Phe His Ala Ala 20 25 30 Ser Met Ser Gln Ile Ala Ser Glu Ala Gln Leu Ser Val Gly Gln Ile 35 40 45 Tyr Arg Tyr Phe Ala Asn Lys Asp Ala Ile Ile Glu Glu Met Val Arg 50 55 60 Arg Ile Ile Asp Phe Arg Ile Ala Gln Met Asp Ile Asp Ala Arg Thr 65 70 75 80 Asp His Phe Pro Glu Val Leu Ala Leu Arg Lys Ser Leu Asn Glu Asp 85 90 95 Asp Asp Ala Leu Met Leu Glu Val Ala Ala Glu Ala Thr Arg Asn Pro 100 105 110 Arg Val Met Ala Met Leu Glu Glu Ala Asp Ala Arg Met Phe Ala Asn 115 120 125 Gly Cys Ala His Met Lys Arg Met His Pro His Leu Ser Glu Glu His 130 135 140 Ile Arg Cys Cys Val Glu Val Phe Ala Thr Met Met Glu Gly Thr Val 145 150 155 160 Tyr Arg Arg Leu Thr Pro Gln Lys Ser Asp Pro Gln His Leu Gln Glu 165 170 175 Ile Tyr Gln Asp Ile Val Ser Met Leu Ile Asn Lys * 180 185 <210> 1376 <211> 374 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1070..2191) <400> 1376 Met Lys Tyr Ile Ala Thr Ser Val Val Ala Met Leu Leu Leu Ser Gly 1 5 10 15 Cys Asp Asn Thr Gln Ser Asn Asn Ser Ser Pro Ser Glu Thr Glu Val 20 25 30 Gly Val Val Thr Val Lys Ser Gln Pro Val Ser Val Val Ser Glu Leu 35 40 45 Thr Gly Arg Thr Ser Ala Ala Leu Ser Ala Glu Val Arg Pro Gln Val 50 55 60 Gly Gly Ile Ile Gln Lys Arg Leu Phe Lys Glu Gly Asp Leu Val Lys 65 70 75 80 Ala Gly Gln Pro Leu Tyr Gln Ile Asp Ala Ala Ser Tyr Gln Ala Ala 85 90 95 Trp Asn Glu Ala Arg Ala Ala Leu Gln Gln Ala Gln Ala Leu Val Lys 100 105 110 Ala Asp Cys Gln Lys Ala Gln Arg Tyr Ala Arg Leu Val Lys Glu Asn 115 120 125 Gly Val Ser Gln Gln Asp Ala Asp Asp Ala Gln Ser Thr Cys Ala Gln 130 135 140 Asp Lys Ala Ser Val Ala Ala Lys Lys Ala Ala Leu Glu Thr Ala Arg 145 150 155 160 Ile Asn Leu Asp Trp Thr Thr Val Thr Ala Pro Ile Ser Gly Arg Ile 165 170 175 Gly Ile Ser Ser Val Thr Pro Gly Ala Leu Val Thr Ala Ser Gln Asp 180 185 190 Thr Ala Leu Thr Thr Ile Arg Gly Leu Asp Thr Met Tyr Val Asp Leu 195 200 205 Thr Arg Ser Ser Val Asp Leu Leu Arg Leu Arg Lys Gln Ser Leu Ala 210 215 220 Thr Asn Ser Asp Thr Met Ser Val Ser Leu Ile Leu Glu Asp Gly Thr 225 230 235 240 Thr Tyr Ser Glu Lys Gly Arg Leu Glu Leu Thr Glu Val Ala Val Asp 245 250 255 Glu Ser Thr Gly Ser Val Thr Leu Arg Ala Ile Phe Pro Asn Pro Gln 260 265 270 Gln Gln Leu Leu Pro Gly Met Phe Val Arg Ala Arg Val Asp Glu Gly 275 280 285 Val Met Glu Asp Ala Ile Leu Ala Pro Gln Gln Gly Val Thr Arg Asp 290 295 300 Ala Lys Gly Asn Ala Thr Ala Leu Val Val Asn Lys Asp Asn Lys Val 305 310 315 320 Glu Gln Arg Thr Leu Glu Thr Gly Glu Thr Tyr Gly Asp Lys Trp Leu 325 330 335 Val Leu Asn Gly Leu His Ser Gly Asp Arg Leu Ile Val Glu Gly Ser 340 345 350 Ala Lys Val Thr Ser Gly Gln Thr Val Lys Ala Val Glu Val Gln Ala 355 360 365 Asn Gly Gly Asn Ala * 370 <210> 1377 <211> 1028 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2191..5274) <400> 1377 Met Phe Ser Arg Phe Phe Val Arg Arg Pro Val Phe Ala Trp Val Ile 1 5 10 15 Ala Ile Leu Ile Met Leu Ala Gly Ile Leu Ala Ile Arg Thr Leu Pro 20 25 30 Val Ala Gln Tyr Pro Asp Val Ala Pro Pro Thr Ile Lys Ile Ser Ala 35 40 45 Thr Tyr Thr Gly Ala Ser Ala Glu Thr Leu Glu Asn Ser Val Thr Gln 50 55 60 Val Ile Glu Gln Gln Leu Thr Gly Leu Asp Asn Leu Leu Tyr Phe Ser 65 70 75 80 Ser Thr Ser Ser Ser Asp Gly Ser Val Ser Ile Asn Val Thr Phe Glu 85 90 95 Gln Gly Thr Asp Pro Asp Thr Ala Gln Val Gln Asn Lys Ile Gln Gln 100 105 110 Ala Glu Ser Arg Leu Pro Ser Glu Val Gln Gln Thr Gly Val Thr Val 115 120 125 Glu Lys Ser Gln Ser Asn Phe Leu Leu Ile Ala Ala Val Tyr Asp Thr 130 135 140 Thr Asp Lys Ala Ser Ser Ser Asp Ile Ala Asp Trp Leu Val Ser Asn 145 150 155 160 Val Gln Asp Pro Leu Ala Arg Val Glu Gly Val Gly Ser Leu Gln Val 165 170 175 Phe Gly Ala Glu Tyr Ala Met Arg Ile Trp Leu Asp Pro Ala Lys Leu 180 185 190 Ala Ser Tyr Ser Leu Met Pro Ser Asp Val Gln Ser Ala Ile Glu Ala 195 200 205 Gln Asn Val Gln Val Thr Ala Gly Lys Ile Gly Ala Leu Pro Ser Pro 210 215 220 Asn Thr Gln Gln Leu Thr Ala Thr Val Arg Ala Gln Ser Arg Leu Gln 225 230 235 240 Thr Val Asp Gln Phe Lys Asn Ile Ile Val Lys Ser Gln Ser Asp Ser 245 250 255 Ala Val Val Arg Ile Lys Asp Val Ala Arg Val Glu Met Gly Ser Glu 260 265 270 Asp Tyr Thr Ala Ile Gly Lys Leu Asn Gly His Pro Ser Ala Gly Val 275 280 285 Ala Val Met Leu Ser Pro Gly Ala Asn Ala Leu Asn Thr Ala Thr Leu 290 295 300 Val Lys Asp Lys Ile Ala Glu Phe Gln Arg Asn Met Pro Gln Gly Tyr 305 310 315 320 Asp Ile Ala Tyr Pro Lys Asp Ser Thr Glu Phe Ile Lys Ile Ser Val 325 330 335 Glu Asp Val Ile Gln Thr Leu Phe Glu Ala Ile Val Leu Val Val Cys 340 345 350 Val Met Tyr Leu Phe Leu Gln Asn Leu Arg Ala Thr Leu Ile Pro Ala 355 360 365 Leu Ala Val Pro Val Val Leu Leu Gly Thr Phe Gly Val Leu Ala Leu 370 375 380 Phe Gly Tyr Ser Ile Asn Thr Leu Thr Leu Phe Ala Met Val Leu Ala 385 390 395 400 Ile Gly Leu Leu Val Asp Asp Ala Ile Val Val Val Glu Asn Val Glu 405 410 415 Arg Ile Met Arg Asp Lys Gly Leu Pro Ala Arg Glu Ala Thr Glu Lys 420 425 430 Ser Met Gly Glu Ile Ser Gly Ala Leu Val Ala Ile Ala Leu Val Leu 435 440 445 Ser Ala Val Phe Leu Pro Met Ala Phe Phe Gly Gly Ser Thr Gly Val 450 455 460 Ile Tyr Arg Gln Phe Ser Ile Thr Ile Ile Ser Ala Met Leu Leu Ser 465 470 475 480 Val Val Val Ala Leu Thr Leu Thr Pro Ala Leu Cys Gly Ser Val Leu 485 490 495 Gln His Val Pro Pro His Lys Lys Gly Phe Phe Gly Ala Phe Asp Arg 500 505 510 Phe Tyr Arg Arg Thr Glu Asp Lys Tyr Gln Arg Gly Val Ile Tyr Val 515 520 525 Leu Arg Arg Ala Ala Arg Thr Met Gly Leu Tyr Leu Val Leu Gly Gly 530 535 540 Gly Met Ala Leu Met Met Trp Lys Leu Pro Gly Ser Phe Leu Pro Thr 545 550 555 560 Glu Asp Gln Gly Glu Ile Met Val Gln Tyr Thr Leu Pro Ala Gly Ala 565 570 575 Thr Ala Ala Arg Thr Ala Glu Val Asn Arg Gln Ile Val Asp Trp Phe 580 585 590 Leu Ile Asn Glu Lys Ala Asn Thr Asp Val Ile Phe Thr Val Asp Gly 595 600 605 Phe Ser Phe Ser Gly Ser Gly Gln Asn Thr Gly Met Ala Phe Val Ser 610 615 620 Leu Lys Asn Trp Ser Gln Arg Lys Gly Ala Glu Asn Thr Ala Gln Ala 625 630 635 640 Ile Ala Leu Arg Ala Thr Lys Glu Leu Gly Thr Ile Arg Asp Ala Thr 645 650 655 Val Phe Ala Met Thr Pro Pro Ala Val Asp Gly Leu Gly Gln Ser Asn 660 665 670 Gly Phe Thr Phe Glu Leu Leu Ala Asn Gly Gly Thr Asp Arg Glu Thr 675 680 685 Leu Leu Gln Met Arg Asn Gln Leu Ile Glu Lys Ala Asn Gln Ser Pro 690 695 700 Glu Leu His Ser Val Arg Ala Asn Asp Leu Pro Gln Met Pro Gln Leu 705 710 715 720 Gln Val Asp Ile Asp Ser Asn Lys Ala Val Ser Leu Gly Leu Ser Leu 725 730 735 Asn Asp Val Thr Asp Thr Leu Ser Ser Ala Trp Gly Gly Thr Tyr Val 740 745 750 Asn Asp Phe Ile Asp Arg Gly Arg Val Lys Lys Val Tyr Ile Gln Gly 755 760 765 Asp Ser Glu Phe Arg Ser Ala Pro Ser Asp Leu Gly Lys Trp Phe Val 770 775 780 Arg Gly Ser Asp Asn Ala Met Thr Pro Phe Ser Ala Phe Ala Thr Thr 785 790 795 800 Arg Trp Leu Tyr Gly Pro Glu Arg Leu Val Arg Tyr Asn Gly Ser Ala 805 810 815 Ala Tyr Glu Ile Gln Gly Glu Asn Ala Thr Gly Phe Ser Ser Gly Asp 820 825 830 Ala Met Thr Lys Met Glu Glu Leu Ala Asn Ser Leu Pro Ala Gly Thr 835 840 845 Thr Trp Ala Trp Ser Gly Leu Ser Leu Gln Glu Lys Leu Ala Ser Gly 850 855 860 Gln Ala Leu Ser Leu Tyr Ala Val Ser Ile Leu Val Val Phe Leu Cys 865 870 875 880 Leu Ala Ala Leu Tyr Glu Ser Trp Ser Val Pro Phe Ser Val Ile Leu 885 890 895 Val Ile Pro Leu Gly Leu Leu Gly Ala Ala Leu Ala Ala Trp Met Arg 900 905 910 Asp Leu Asn Asn Asp Val Tyr Phe Gln Val Ala Leu Leu Thr Thr Ile 915 920 925 Gly Leu Ser Ser Lys Asn Ala Ile Leu Ile Val Glu Phe Ala Glu Ala 930 935 940 Ala Val Ala Glu Gly Tyr Ser Leu Ser Arg Ala Ala Leu Arg Ala Ala 945 950 955 960 Gln Thr Arg Leu Arg Pro Ile Ile Met Thr Ser Leu Ala Phe Ile Ala 965 970 975 Gly Gly Asn Ala Ala Gly Asp Ser Asn Arg Leu Arg Gly Glu Gln Pro 980 985 990 His Arg His Trp Tyr Gly His Tyr Trp Arg Tyr Ala Asp Arg Tyr Val 995 1000 1005 Ala Gly Tyr Phe Leu Cys Ser Ser Val Phe Cys Thr Gly Glu Ala Phe 1010 1015 1020 Val Cys Arg * 1025 <210> 1378 <211> 458 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5297..6670) <400> 1378 Met Leu Arg Arg Ser Leu Ile Phe Leu Val Leu Leu Ser Ala Gly Cys 1 5 10 15 Val Ser Leu Asp Pro His Tyr Ser Thr Pro Glu Ser Pro Ile Pro Ala 20 25 30 Thr Leu Pro Gly Ala Gln Gly Gln Gly Lys Ala Ile Ser His Asp Trp 35 40 45 Gln Gln Val Ile His Asp Pro Arg Leu Gln Gln Val Val Thr Ile Ala 50 55 60 Leu Asn Ser Asn Arg Asp Val Gln Lys Ala Ile Ala Asp Ile Asp Ser 65 70 75 80 Ala Arg Ala Leu Tyr Gly Gln Thr Asn Ala Ser Leu Phe Pro Thr Val 85 90 95 Asn Ala Ala Leu Ser Ser Thr Arg Ser Arg Ser Leu Ala Asn Gly Thr 100 105 110 Glu Thr Thr Ala Glu Ala Asp Gly Thr Val Ser Ser Phe Thr Leu Asp 115 120 125 Leu Phe Gly Arg Asn Gln Ser Leu Ser Arg Ala Ala Arg Glu Thr Trp 130 135 140 Leu Ala Ser Glu Phe Thr Ala Gln Asn Thr Arg Leu Thr Leu Ile Ala 145 150 155 160 Glu Ile Ser Thr Ala Trp Leu Thr Leu Ala Ala Asp Asn Ser Asn Leu 165 170 175 Ala Leu Ala Lys Glu Thr Met Thr Ser Ala Glu Asn Ser Leu Lys Ile 180 185 190 Ile Gln Arg Gln Gln Gln Val Gly Thr Ala Ala Ala Thr Asp Val Ser 195 200 205 Glu Ala Met Ser Val Tyr Gln Gln Ala Arg Ala Ser Val Ala Ser Tyr 210 215 220 Gln Thr Gln Val Met Gln Asp Lys Asn Ala Leu Asn Leu Leu Ala Gly 225 230 235 240 Thr Thr Leu Glu Glu Asn Leu Leu Pro Gly Thr Leu Glu Ser Leu Pro 245 250 255 Glu Gln Met Ile Ser Leu Val Pro Ala Gly Val Ser Ser Asp Val Leu 260 265 270 Leu Arg Arg Pro Asp Ile Gln Glu Ala Glu His Asn Leu Lys Ser Ala 275 280 285 Asn Ala Asp Ile Gly Ala Ala Arg Ala Asn Phe Phe Pro Thr Ile Ser 290 295 300 Leu Thr Ala Ser Ala Gly Val Gly Ser Asp Ala Leu Ser Ser Leu Phe 305 310 315 320 Ser His Gly Met Gln Ile Trp Ser Phe Thr Pro Ser Val Thr Leu Pro 325 330 335 Leu Phe Thr Gly Gly Ser Asn Leu Ala Gln Leu Arg Tyr Ala Glu Ala 340 345 350 Gln Lys Arg Gly Leu Ile Ala Thr Tyr Glu Lys Thr Val Gln Arg Ala 355 360 365 Phe Lys Asp Val Ala Asn Ala Leu Ala Arg Arg Thr Thr Leu Glu Glu 370 375 380 Gln Leu Asp Ala Gln Arg Gln Tyr Val Lys Ala Glu Gln Gln Thr Val 385 390 395 400 Asp Val Gly Leu Arg Arg Tyr Gln Thr Gly Val Gly Asp Tyr Leu Thr 405 410 415 Val Leu Thr Ala Gln Arg Ser Leu Trp Ser Ala Gln Gln Glu Leu Leu 420 425 430 Ala Leu Gln Leu Thr Asp Phe Thr Asn Arg Ile Thr Leu Trp Gln Ser 435 440 445 Leu Gly Gly Gly Met Ser Ser Leu Lys * 450 455 <210> 1379 <211> 388 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6679..7842) <400> 1379 Met Ala Arg Val Ser Leu Ser Trp Ala Leu Ile Leu Gly Leu Leu Ala 1 5 10 15 Gly Ile Gly Pro Met Cys Thr Asp Leu Tyr Leu Pro Ala Leu Pro Glu 20 25 30 Met Ser Glu Gln Leu Ala Ala Thr Thr Thr Ile Thr Gln Leu Thr Leu 35 40 45 Thr Ala Ser Leu Ile Gly Leu Gly Val Gly Gln Leu Leu Phe Gly Pro 50 55 60 Leu Ser Asp Lys Ile Gly Arg Lys Arg Pro Leu Ile Leu Ser Leu Leu 65 70 75 80 Leu Phe Ile Val Ser Ser Ile Leu Cys Ala Thr Thr Asn Asn Ile Tyr 85 90 95 Trp Leu Val Val Trp Arg Phe Ile Gln Gly Ile Ala Gly Ala Gly Gly 100 105 110 Ser Val Leu Ser Arg Ser Ile Ala Arg Asp Lys Tyr Gln Gly Val Thr 115 120 125 Leu Thr Gln Phe Phe Ala Leu Leu Met Thr Val Asn Gly Leu Ala Pro 130 135 140 Val Leu Ser Pro Val Leu Gly Gly Tyr Ile Val Ser Thr Phe Asp Trp 145 150 155 160 Arg Thr Leu Phe Trp Val Met Ala Glu Ile Ser Thr Val Leu Leu Leu 165 170 175 Gly Cys Val Leu Phe Ile Asn Glu Thr Leu Pro Glu Asn Lys Arg Gly 180 185 190 Ser Ser Leu Leu Leu Thr Gly Arg Ser Val Val Gln Asn Arg Arg Phe 195 200 205 Met Arg Phe Cys Leu Ile Gln Ser Phe Met Leu Ala Gly Leu Phe Ala 210 215 220 Tyr Ile Gly Ser Ser Ser Phe Val Leu Gln Lys Glu Phe Gly Phe Ser 225 230 235 240 Pro Met Gln Phe Ser Leu Val Phe Gly Leu Asn Gly Ile Gly Leu Ile 245 250 255 Ile Ala Ser Trp Ile Phe Ser Arg Leu Ala Arg Arg Ile Asn Ala Met 260 265 270 Thr Leu Leu Arg Gly Gly Leu Ile Ala Ala Ile Leu Cys Ala Leu Leu 275 280 285 Thr Val Leu Cys Ala Trp Thr Gln Leu Pro Ile Pro Ala Leu Val Ala 290 295 300 Leu Phe Phe Thr Ile Ala Phe Cys Ser Gly Ile Gly Thr Val Gly Gly 305 310 315 320 Ala Glu Ala Met Ser Ala Val Gly Thr Gln Glu Ser Gly Thr Ala Ser 325 330 335 Ala Leu Met Gly Met Ser Met Phe Val Phe Gly Gly Ile Ala Ala Pro 340 345 350 Leu Ser Gly Phe Gly Gly Glu Thr Leu Leu Lys Met Ser Leu Ala Ile 355 360 365 Thr Val Cys Tyr Thr Leu Ala Phe Leu Val Ala Leu Thr Arg Ile Asp 370 375 380 Asn Gln Lys * 385 <210> 1380 <211> 7818 <212> DNA <213> Escherichia coli O157:H7 <400> 1380 taatgaaaat aagatgaaaa ttagcgtgaa atataaattt tggtgatgtg aataaagcgg 60 ctatttagcc gctttattgg tttttcgagg gcaggtaaat tagtttaccg ccgcgtcagt 120 gagtgcatct gcaaggtgta gttgggtttg ctgggcggat tggatatgat tctttaattc 180 ttcacatagt ttataaaaaa tatgtagttt actcattatt ttttttgctt ctgagctagg 240 aggaatagca acaggacaac ctctgagctg ggttttatta atagaagcta aattagtggt 300 ttgcttactt gcgttagcaa aatattgtct tgagaatggg ctattcatat atgtttctaa 360 ccaatatgga tcaacatctt gccctatatt tcgtcctttg aatacatggt tttgatttgc 420 tatataccag tcatgacacc atactgtagt tctcccgact gtatcccagt cgccgccttc 480 tgttatcaat aaatctccct tgactacttg atatttttct ttttcctcaa tagggatttc 540 aatctgttta atttccgtaa gatcaagata tccgcgttgg acgtttgcaa cacgtaaata 600 aggaactttt accaaagttc tatttgataa atttcttcct ttagtgatac cactttgaat 660 atcaataata tcttcaaata aacaccactc ccacccttcc ggaagttcaa acggtttttc 720 ctcatcgcta attggcggca acggtttttg tttttttatt tttccttctt tcaccagttg 780 agctttttcc tgcgcaattc gtttgagcag ttcagaggct ggttcatcat tcggatcctg 840 cggcacaagt ttgcccatta cggccagttg cagaatggtc tgttttaacg catccacgct 900 ggcttcggtg gtaaatagag tgtcgaaata ctcgctaata cgcgcccagt tttcagccag 960 ttcctcggcg gtttggctgt ctgtaagcgt tcccaacagg gtttcaacca gttgttgatg 1020 tgcgtccaga ctggtcaggg attgctgttc cagttggtcg cagagggaca ttaattcttt 1080 gattttgttt gcgatgcgaa cttgttccaa ggatggagga actggagtta ttccagaaaa 1140 aaattgtttg tcattgattg ctggataggc aacccctgtc tgacaatttt caacataaca 1200 aacaaatacc ggagaacgta gataataata aatgaaatta gcatccatcg ccgtatatgg 1260 atgaataata gcgaaggcag tactagcgat cggttcaggt agtatttcgt tttcaataat 1320 agctatattt aacaaatacg ggcgaacagt agagtatatg atagtccctt gctgaacaat 1380 ttttctcgct cgcgatgggg catctttcgc tgaaagaata gatagctctt caataattcc 1440 atattcttta tttattgaac caacatcaat gtaagtaaaa tctttatctg gagttttttg 1500 tccccagtca tgtccaattt cactaatacg cacccactcc catccctccg gcaattcaaa 1560 cggcttctct tcctcactaa tttccggcag tggtttttgc tttttaattt taccttgctt 1620 caccagctct gctttttctg ccgcaatacg cttcagcagc tccgacgccg gttcatcgtt 1680 cgggtcctgc ggcaccagtt taccgcgcac agccagttcc agaatcagct cacgtaattt 1740 cttaatgcca tataaatcaa tttttccgga actgccgcgc ccggcggtgg aacgggtttg 1800 caacgccgag gtccaggttt ccatatgatc aacgatcagc ttttccacac tcattagtta 1860 acctccttgc cagacagcgc agcgccaaga atatcgcgca gttgattacg cagcgtctgg 1920 atctccgcct gctgttttgc atactgcgct aacagctcgg ccggatcatg gctgacggtt 1980 tccgcctgat gtgggttttt aatatccaga ttgaagttac gcgcaatcac gtcatcaatg 2040 ctgactttcc acgcctgctc attctctacg cggctggcaa aaccatcggc ctcgttaccc 2100 caccagtcga tctccgcctg aaactcttca aacttcatcg gcttagtttt gctgtagttt 2160 tttacgcccg ccggatacgg atgctcatag aaccaaatct ctttggttgg ctgacctttg 2220 gtaaagaaca acaggttggt tttaatgccg gtataggggt taaacacacc attcggtaag 2280 cgcacgatgg tatgcaggtt gcactcttcg gtaagtagct ttttgatttt ggttttaacg 2340 ccttcgccaa atagtgtgcc atccggcaat accaccgccg cgcgaccatt tttcgccagt 2400 acttccacaa tcagttgcag gaacaaatcc gccgtttcgc gggtttgcat ctctgccgga 2460 aagttcttct caataccgtc ttcttccgtg ccaccaaacg gcgggttggt aacaatgaca 2520 tccagttgct catcccggga ggaaagcggt ttgttcagag tgttgtcgtg acgaatttgc 2580 actggcactt caatgccgtg tagcagcata ttggtggtcg ccagcaggtg cggaagctgt 2640 tttttctcaa caccgtggat ctgttgttgc agcgtctgat gatcggcgac gctcttcacg 2700 tatttgttct ttacatgatc aaatgcgcag gcaagaaaac cgcccgtacc gcaggccggg 2760 tccataatgg attcgccgag tttcggatca acgcgatcca ccataaagcg agtgacggcg 2820 cgtggagtat agaattcgcc cgcattgccc gcagattgca gatctttaag gatctgttcg 2880 taaatatcac caaacagatg gcgttcgctg gcgctggtaa agtcaatttc gttcagctta 2940 ttgatcacct gacgcagtag cgtaccgttt ttcatatagt tataggcatc gctgaacgcc 3000 tgcttcacca cgtagccgcg tgggttttta tcgataggcg cagtgaggtt tttcaacgcc 3060 gggaacagat catcattaac gaattccagc agggaatcac cggtaatgcc ctgcgcgttg 3120 gcggcccaac tgcgccataa ataacgctgt gggatcggat attgatagtt atcctgctcc 3180 agttccagcg cctcttcctg ggcatcgaag attttcaaaa acagcagcca ggagagctga 3240 ccgagacgct gcgcatcgcc atccacaccg gcatctttgc gcataatatc ttgtaatgat 3300 ttgattactg agctgataga catgttgtat tccatgaaaa acaaggcctt ctgcaacatg 3360 atggttgcag aaggcgcaaa agagagttgt taagcagagc ggggcggtaa ttggtagatt 3420 tcgttttcca gctcgctgag cgcctgatta tacccgttac ggtcgccaaa tccggtttta 3480 ataatctccg gtaaggtgcc catgctgtcg aatggcttaa gtttcagcac ctgaatactt 3540 tcgatctcct gtacgcccgc atcggcgtat ttatccagca gattatcgag cacggcttgc 3600 gctgcttcag agtattttgt gaagtagttc cgcttgcgca cgttctcggc gcgctctttg 3660 cgggttaacg gcggctgacc atacactacg tggcaaagca tgtcgaacgg gtcgagatct 3720 ttaccgactt cttctgccag tacttcccag atgatcccct gttgctccag ctcgtgaatg 3780 atcgcttctt tgcgatcggc gtcctgccac ttgcgggtaa agtcatccag cgaggcatat 3840 tctttgagca gtgttttgcg ggtgtaatct ttaaaggatt cggtaaccag tttaccgtcg 3900 gcgtcgtaat actgaacacg ctgggcaata acgcccactg ctacaccgtt gacgtgaaac 3960 ttgcggattt tcttctcgtc ttcttccgga agtgggccga catcatcggt atctttaacc 4020 tggtatggtg gcgcaggcgg ttcatcaacg cctgttacct gttcgtcgtc atgttcgctg 4080 atttcttcga gtttctcttc aaaatcagat tctggatcgg cgatatcctc tggtgtggta 4140 tccatgactt tttcgggaat gccatcgaaa cgctcatcgg caaacagttc ggtggctttt 4200 ttaaagtcga ggatggtaaa ccagagtttg ccgtaacgtt cgtcgatgcg tgtaccacga 4260 ccgataatct gcttgaattt ggtcatcgac tggatgttct ggtccagtac taccagtttg 4320 caggttttag catccacacc ggtggtcatc agctctgaag tggtcgcgat aaccgggtac 4380 ggttttttcg ggttgatgaa gttatccaac tgagctttgc caatttcatc atcgccggtg 4440 attttcatga cgtatttgtc gttctttttc acctgctccg ggttgagatt aaccagggcg 4500 cggcgcatac gttctgcatg atcgatgtcg ttacagaaga cgatggtttt atccatcgga 4560 ttggtacgct tgaggtagtc ggtaatggtt ctggcaacca gttctgtgcg ttcgtcgatt 4620 accatcgtgc gatcgaaatc tttctggtta tagatacgat cgtcgatcac ttcgccgttt 4680 aagtcagttt gccctttggt tgggcgccag ccttgcagat caacatcaat atcaacacgg 4740 acaactttat aaggggcgag gaagccgtct tcgatccctt cttttagtga gtagacgtaa 4800 accggatcgc cgaagtaatc cgtgctggag acttcatgcg tctcttttgg cgtggcggtt 4860 aagccaattt gggtggcgga actaaaataa tcaaggattt ctcgccaggc gctgtcttcg 4920 gatgcgctgc cgcgatggca ttcgtcgatc acgatcagat cgaagaaatc tggtgcgact 4980 tgtttaaacg ctttttggtc ttcctccggg ccagttatag cctgatagag cgcgaggtga 5040 atttcataag cgggatcaat ggtgcgtccg ctgactttgg tcattgccgt accaaatggc 5100 tggaaatcat tatttttggt ttggtcgacc agaatattgc gatcggcaag gaacaaaatg 5160 cgttttttat tttttgattt ccacaggcgc cagatgatct ggaatgcggt ataggttttc 5220 cctgttccgg tcgccatgac cagcagaacg cggttttgcc cgttggagac ggcttcaatg 5280 gttttgttga ttgcctgaag ctggtaataa cgtggcgatt taccgctgcc atcgtcgtaa 5340 tagtcctgag taatcaccgg aagctgagct tgtgtgtatc ctttccagag gcagaatttt 5400 tgccagagtt cagcggggga ggggaagtca tccagcgtta tttgcttttc aaggcattca 5460 ccttcggctg cggtggcatc gcggaagata aagccatcac cgttggtggc aaaaacaaaa 5520 ggaacgtcca gcaggcgcgc atattcaatg ccctgttgca tccctttgcc aatttcatgt 5580 ttgttggctt ttgcttcaat cacggctaag ggaatgccag gtttgtgata cagcacgatg 5640 tcagcagatt ttaccgttct gcgtgccgca actttaccac gtacgatgac tttaccgtcc 5700 cggagtttga cctcctgtct gatttgcgtt gtgttgtccc agcctgcatt gagaatggct 5760 ggcataacgc atttggtaat gatgtctgct tccgtcaggt tacttaggtt cagttccgcc 5820 atggggtatt ctcgctttta tcaggacgat tctgattgta cataaaatca atagcctggc 5880 tatgatttag ggcggtgttt caacgtaaag tacgtagcag agatcacatt gatatctctg 5940 ttatatcttg cttgaattaa tctgggcata tcagagacag ataaacagaa gttacaggaa 6000 ccatatcaac tctaacaaaa tatataaaaa tcttatagtt gcgtttcttt cgagcaagaa 6060 agataatgtt attgttgatt gtttgattgg gtatatgaaa tggaagctaa agaatgtaag 6120 gtgcaggata tccttactga aaacaaaaag tttattattc cttcttatca gcgtccttac 6180 agttggacgg tagataatgc agagcaactc attgatgaca tttataaaag ctctcaatca 6240 gaagagaatg gatattttat tgggagtatg atttgtatca ataaagggca aaatcagtat 6300 gaagttgtag atggacaaca acgtcttaca acgttaagca ttattgtctc cgagctaaaa 6360 aaatcatccc gattcagggg ataaaagatg atttgcaaaa aagagttctg cctattgatg 6420 tttattctga tgaaacagat gaaccaagac taattgttag aaaaaaagag catgatcttt 6480 ataaatatta tatactgcag gattctaaag attataaacc tgaaaagcca tcggatactg 6540 agttagtatt cattagcaac gctgaaacaa ttagagatta tttgttgcgg ttatctgttg 6600 atgagttgaa gttgcttgct aaatatattt tgcaaaatgt atatatcgta tttgtgcaaa 6660 cagatgattt cgcatcatca tttagactct ttaatgtatt aaatagtcga ggtttacctt 6720 taagtaatgc agatctttta aaaaatgcac tgtttgaatc agcttctaca cataataaaa 6780 aatcagagca aatagaatca gcatggtcgc aaattgaaga tatggtcgga gtgagacggc 6840 ttgataaatt tcttactctt cataagcttt ccgagaaaaa agatcgtgac agggtgttac 6900 aaaaaggttt tgaagctttt attgaaaatc tccagcagca atttgatgga gatgctattg 6960 ctatgtcact gatgttggtt aattctgcaa aaaattatac taagatttta gagaatgatt 7020 ttgaacaccc ttcaatacga cgaaaaatag catcgctaag taatttaggg gtagatgagt 7080 ggattcctcc ggttatggca ttcatgaatc gaatggctcg tacagaagat tttaatttag 7140 atgatttttc tcaatttatt accgcctttg agaaggtata tatgcatggg tggttaaaaa 7200 aacaaattaa aagccaaaga gaaatggttt gttattcagc tctggtagca ataaataatg 7260 atatgccttt tgattctgtg ataaatcaga taaaccaaca tgcagataat tcaggtttta 7320 tagctgctct ggatgaagat ttatatgagc ctcgtccgaa tcaagtgaac ttaataaaag 7380 caattttgct tcgcttagat atggagcaac aagatgagag cgtgattaaa acctatacgg 7440 ggagaatcac aattgagcat attcttcctc aagcattagt taatgaatac tggattaata 7500 gattccaacc tcaagagcat gtctactggc tgcataaaat aggtaattta acactcataa 7560 gtggttccaa aaattctgaa gcacaacact atgattttat caaaaagaaa tctatttatg 7620 agaaacttaa tagtaaaagc tcttttgatt taacaaaaga tgtttgtaat tcttcagaat 7680 ggggattggc tgaactgaaa atgagacatg aaaaaatgaa aacgcaattg aagaagcttt 7740 ggttggtctg acatatctaa agagttccac tcgtaataat gttgcggtgg aactctcaaa 7800 aagttgatct ttcccgaa 7818 <210> 1381 <211> 585 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(100..1854) <400> 1381 Met Ser Val Glu Lys Leu Ile Val Asp His Met Glu Thr Trp Thr Ser 1 5 10 15 Ala Leu Gln Thr Arg Ser Thr Ala Gly Arg Gly Ser Ser Gly Lys Ile 20 25 30 Asp Leu Tyr Gly Ile Lys Lys Leu Arg Glu Leu Ile Leu Glu Leu Ala 35 40 45 Val Arg Gly Lys Leu Val Pro Gln Asp Pro Asn Asp Glu Pro Ala Ser 50 55 60 Glu Leu Leu Lys Arg Ile Ala Ala Glu Lys Ala Glu Leu Val Lys Gln 65 70 75 80 Gly Lys Ile Lys Lys Gln Lys Pro Leu Pro Glu Ile Ser Glu Glu Glu 85 90 95 Lys Pro Phe Glu Leu Pro Glu Gly Trp Glu Trp Val Arg Ile Ser Glu 100 105 110 Ile Gly His Asp Trp Gly Gln Lys Thr Pro Asp Lys Asp Phe Thr Tyr 115 120 125 Ile Asp Val Gly Ser Ile Asn Lys Glu Tyr Gly Ile Ile Glu Glu Leu 130 135 140 Ser Ile Leu Ser Ala Lys Asp Ala Pro Ser Arg Ala Arg Lys Ile Val 145 150 155 160 Gln Gln Gly Thr Ile Ile Tyr Ser Thr Val Arg Pro Tyr Leu Leu Asn 165 170 175 Ile Ala Ile Ile Glu Asn Glu Ile Leu Pro Glu Pro Ile Ala Ser Thr 180 185 190 Ala Phe Ala Ile Ile His Pro Tyr Thr Ala Met Asp Ala Asn Phe Ile 195 200 205 Tyr Tyr Tyr Leu Arg Ser Pro Val Phe Val Cys Tyr Val Glu Asn Cys 210 215 220 Gln Thr Gly Val Ala Tyr Pro Ala Ile Asn Asp Lys Gln Phe Phe Ser 225 230 235 240 Gly Ile Thr Pro Val Pro Pro Ser Leu Glu Gln Val Arg Ile Ala Asn 245 250 255 Lys Ile Lys Glu Leu Met Ser Leu Cys Asp Gln Leu Glu Gln Gln Ser 260 265 270 Leu Thr Ser Leu Asp Ala His Gln Gln Leu Val Glu Thr Leu Leu Gly 275 280 285 Thr Leu Thr Asp Ser Gln Thr Ala Glu Glu Leu Ala Glu Asn Trp Ala 290 295 300 Arg Ile Ser Glu Tyr Phe Asp Thr Leu Phe Thr Thr Glu Ala Ser Val 305 310 315 320 Asp Ala Leu Lys Gln Thr Ile Leu Gln Leu Ala Val Met Gly Lys Leu 325 330 335 Val Pro Gln Asp Pro Asn Asp Glu Pro Ala Ser Glu Leu Leu Lys Arg 340 345 350 Ile Ala Gln Glu Lys Ala Gln Leu Val Lys Glu Gly Lys Ile Lys Lys 355 360 365 Gln Lys Pro Leu Pro Pro Ile Ser Asp Glu Glu Lys Pro Phe Glu Leu 370 375 380 Pro Glu Gly Trp Glu Trp Cys Leu Phe Glu Asp Ile Ile Asp Ile Gln 385 390 395 400 Ser Gly Ile Thr Lys Gly Arg Asn Leu Ser Asn Arg Thr Leu Val Lys 405 410 415 Val Pro Tyr Leu Arg Val Ala Asn Val Gln Arg Gly Tyr Leu Asp Leu 420 425 430 Thr Glu Ile Lys Gln Ile Glu Ile Pro Ile Glu Glu Lys Glu Lys Tyr 435 440 445 Gln Val Val Lys Gly Asp Leu Leu Ile Thr Glu Gly Gly Asp Trp Asp 450 455 460 Thr Val Gly Arg Thr Thr Val Trp Cys His Asp Trp Tyr Ile Ala Asn 465 470 475 480 Gln Asn His Val Phe Lys Gly Arg Asn Ile Gly Gln Asp Val Asp Pro 485 490 495 Tyr Trp Leu Glu Thr Tyr Met Asn Ser Pro Phe Ser Arg Gln Tyr Phe 500 505 510 Ala Asn Ala Ser Lys Gln Thr Thr Asn Leu Ala Ser Ile Asn Lys Thr 515 520 525 Gln Leu Arg Gly Cys Pro Val Ala Ile Pro Pro Ser Ser Glu Ala Lys 530 535 540 Lys Ile Met Ser Lys Leu His Ile Phe Tyr Lys Leu Cys Glu Glu Leu 545 550 555 560 Lys Asn His Ile Gln Ser Ala Gln Gln Thr Gln Leu His Leu Ala Asp 565 570 575 Ala Leu Thr Asp Ala Ala Val Asn * 580 <210> 1382 <211> 494 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1854..3335) <400> 1382 Met Glu Tyr Asn Met Ser Ile Ser Ser Val Ile Lys Ser Leu Gln Asp 1 5 10 15 Ile Met Arg Lys Asp Ala Gly Val Asp Gly Asp Ala Gln Arg Leu Gly 20 25 30 Gln Leu Ser Trp Leu Leu Phe Leu Lys Ile Phe Asp Ala Gln Glu Glu 35 40 45 Ala Leu Glu Leu Glu Gln Asp Asn Tyr Gln Tyr Pro Ile Pro Gln Arg 50 55 60 Tyr Leu Trp Arg Ser Trp Ala Ala Asn Ala Gln Gly Ile Thr Gly Asp 65 70 75 80 Ser Leu Leu Glu Phe Val Asn Asp Asp Leu Phe Pro Ala Leu Lys Asn 85 90 95 Leu Thr Ala Pro Ile Asp Lys Asn Pro Arg Gly Tyr Val Val Lys Gln 100 105 110 Ala Phe Ser Asp Ala Tyr Asn Tyr Met Lys Asn Gly Thr Leu Leu Arg 115 120 125 Gln Val Ile Asn Lys Leu Asn Glu Ile Asp Phe Thr Ser Ala Ser Glu 130 135 140 Arg His Leu Phe Gly Asp Ile Tyr Glu Gln Ile Leu Lys Asp Leu Gln 145 150 155 160 Ser Ala Gly Asn Ala Gly Glu Phe Tyr Thr Pro Arg Ala Val Thr Arg 165 170 175 Phe Met Val Asp Arg Val Asp Pro Lys Leu Gly Glu Ser Ile Met Asp 180 185 190 Pro Ala Cys Gly Thr Gly Gly Phe Leu Ala Cys Ala Phe Asp His Val 195 200 205 Lys Asn Lys Tyr Val Lys Ser Val Ala Asp His Gln Thr Leu Gln Gln 210 215 220 Gln Ile His Gly Val Glu Lys Lys Gln Leu Pro His Leu Leu Ala Thr 225 230 235 240 Thr Asn Met Leu Leu His Gly Ile Glu Val Pro Val Gln Ile Arg His 245 250 255 Asp Asn Thr Leu Asn Lys Pro Leu Ser Ser Arg Asp Glu Gln Leu Asp 260 265 270 Val Ile Val Thr Asn Pro Pro Phe Gly Gly Thr Glu Glu Asp Gly Ile 275 280 285 Glu Lys Asn Phe Pro Ala Glu Met Gln Thr Arg Glu Thr Ala Asp Leu 290 295 300 Phe Leu Gln Leu Ile Val Glu Val Leu Ala Lys Asn Gly Arg Ala Ala 305 310 315 320 Val Val Leu Pro Asp Gly Thr Leu Phe Gly Glu Gly Val Lys Thr Lys 325 330 335 Ile Lys Lys Leu Leu Thr Glu Glu Cys Asn Leu His Thr Ile Val Arg 340 345 350 Leu Pro Asn Gly Val Phe Asn Pro Tyr Thr Gly Ile Lys Thr Asn Leu 355 360 365 Leu Phe Phe Thr Lys Gly Gln Pro Thr Lys Glu Ile Trp Phe Tyr Glu 370 375 380 His Pro Tyr Pro Ala Gly Val Lys Asn Tyr Ser Lys Thr Lys Pro Met 385 390 395 400 Lys Phe Glu Glu Phe Gln Ala Glu Ile Asp Trp Trp Gly Asn Glu Ala 405 410 415 Asp Gly Phe Ala Ser Arg Val Glu Asn Glu Gln Ala Trp Lys Val Ser 420 425 430 Ile Asp Asp Val Ile Ala Arg Asn Phe Asn Leu Asp Ile Lys Asn Pro 435 440 445 His Gln Ala Glu Thr Val Ser His Asp Pro Ala Glu Leu Leu Ala Gln 450 455 460 Tyr Ala Lys Gln Gln Ala Glu Ile Gln Thr Leu Arg Asn Gln Leu Arg 465 470 475 480 Asp Ile Leu Gly Ala Ala Leu Ser Gly Lys Glu Val Asn * 485 490 <210> 1383 <211> 811 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3390..5822) <400> 1383 Met Ala Glu Leu Asn Leu Ser Asn Leu Thr Glu Ala Asp Ile Ile Thr 1 5 10 15 Lys Cys Val Met Pro Ala Ile Leu Asn Ala Gly Trp Asp Asn Thr Thr 20 25 30 Gln Ile Arg Gln Glu Val Lys Leu Arg Asp Gly Lys Val Ile Val Arg 35 40 45 Gly Lys Val Ala Ala Arg Arg Thr Val Lys Ser Ala Asp Ile Val Leu 50 55 60 Tyr His Lys Pro Gly Ile Pro Leu Ala Val Ile Glu Ala Lys Ala Asn 65 70 75 80 Lys His Glu Ile Gly Lys Gly Met Gln Gln Gly Ile Glu Tyr Ala Arg 85 90 95 Leu Leu Asp Val Pro Phe Val Phe Ala Thr Asn Gly Asp Gly Phe Ile 100 105 110 Phe Arg Asp Ala Thr Ala Ala Glu Gly Glu Cys Leu Glu Lys Gln Ile 115 120 125 Thr Leu Asp Asp Phe Pro Ser Pro Ala Glu Leu Trp Gln Lys Phe Cys 130 135 140 Leu Trp Lys Gly Tyr Thr Gln Ala Gln Leu Pro Val Ile Thr Gln Asp 145 150 155 160 Tyr Tyr Asp Asp Gly Ser Gly Lys Ser Pro Arg Tyr Tyr Gln Leu Gln 165 170 175 Ala Ile Asn Lys Thr Ile Glu Ala Val Ser Asn Gly Gln Asn Arg Val 180 185 190 Leu Leu Val Met Ala Thr Gly Thr Gly Lys Thr Tyr Thr Ala Phe Gln 195 200 205 Ile Ile Trp Arg Leu Trp Lys Ser Lys Asn Lys Lys Arg Ile Leu Phe 210 215 220 Leu Ala Asp Arg Asn Ile Leu Val Asp Gln Thr Lys Asn Asn Asp Phe 225 230 235 240 Gln Pro Phe Gly Thr Ala Met Thr Lys Val Ser Gly Arg Thr Ile Asp 245 250 255 Pro Ala Tyr Glu Ile His Leu Ala Leu Tyr Gln Ala Ile Thr Gly Pro 260 265 270 Glu Glu Asp Gln Lys Ala Phe Lys Gln Val Ala Pro Asp Phe Phe Asp 275 280 285 Leu Ile Val Ile Asp Glu Cys His Arg Gly Ser Ala Ser Glu Asp Ser 290 295 300 Ala Trp Arg Glu Ile Leu Asp Tyr Phe Ser Ser Ala Thr Gln Ile Gly 305 310 315 320 Leu Thr Ala Thr Pro Lys Glu Thr His Glu Val Ser Ser Thr Asp Tyr 325 330 335 Phe Gly Asp Pro Val Tyr Val Tyr Ser Leu Lys Glu Gly Ile Glu Asp 340 345 350 Gly Phe Leu Ala Pro Tyr Lys Val Val Arg Val Asp Ile Asp Val Asp 355 360 365 Leu Gln Gly Trp Arg Pro Thr Lys Gly Gln Thr Asp Leu Asn Gly Glu 370 375 380 Val Ile Asp Asp Arg Ile Tyr Asn Gln Lys Asp Phe Asp Arg Thr Met 385 390 395 400 Val Ile Asp Glu Arg Thr Glu Leu Val Ala Arg Thr Ile Thr Asp Tyr 405 410 415 Leu Lys Arg Thr Asn Pro Met Asp Lys Thr Ile Val Phe Cys Asn Asp 420 425 430 Ile Asp His Ala Glu Arg Met Arg Arg Ala Leu Val Asn Leu Asn Pro 435 440 445 Glu Gln Val Lys Lys Asn Asp Lys Tyr Val Met Lys Ile Thr Gly Asp 450 455 460 Asp Glu Ile Gly Lys Ala Gln Leu Asp Asn Phe Ile Asn Pro Lys Lys 465 470 475 480 Pro Tyr Pro Val Ile Ala Thr Thr Ser Glu Leu Met Thr Thr Gly Val 485 490 495 Asp Ala Lys Thr Cys Lys Leu Val Val Leu Asp Gln Asn Ile Gln Ser 500 505 510 Met Thr Lys Phe Lys Gln Ile Ile Gly Arg Gly Thr Arg Ile Asp Glu 515 520 525 Arg Tyr Gly Lys Leu Trp Phe Thr Ile Leu Asp Phe Lys Lys Ala Thr 530 535 540 Glu Leu Phe Ala Asp Glu Arg Phe Asp Gly Ile Pro Glu Lys Val Met 545 550 555 560 Asp Thr Thr Pro Glu Asp Ile Ala Asp Pro Glu Ser Asp Phe Glu Glu 565 570 575 Lys Leu Glu Glu Ile Ser Glu His Asp Asp Glu Gln Val Thr Gly Val 580 585 590 Asp Glu Pro Pro Ala Pro Pro Tyr Gln Val Lys Asp Thr Asp Asp Val 595 600 605 Gly Pro Leu Pro Glu Glu Asp Glu Lys Lys Ile Arg Lys Phe His Val 610 615 620 Asn Gly Val Ala Val Gly Val Ile Ala Gln Arg Val Gln Tyr Tyr Asp 625 630 635 640 Ala Asp Gly Lys Leu Val Thr Glu Ser Phe Lys Asp Tyr Thr Arg Lys 645 650 655 Thr Leu Leu Lys Glu Tyr Ala Ser Leu Asp Asp Phe Thr Arg Lys Trp 660 665 670 Gln Asp Ala Asp Arg Lys Glu Ala Ile Ile His Glu Leu Glu Gln Gln 675 680 685 Gly Ile Ile Trp Glu Val Leu Ala Glu Glu Val Gly Lys Asp Leu Asp 690 695 700 Pro Phe Asp Met Leu Cys His Val Val Tyr Gly Gln Pro Pro Leu Thr 705 710 715 720 Arg Lys Glu Arg Ala Glu Asn Val Arg Lys Arg Asn Tyr Phe Thr Lys 725 730 735 Tyr Ser Glu Ala Ala Gln Ala Val Leu Asp Asn Leu Leu Asp Lys Tyr 740 745 750 Ala Asp Ala Gly Val Gln Glu Ile Glu Ser Ile Gln Val Leu Lys Leu 755 760 765 Lys Pro Phe Asp Ser Met Gly Thr Leu Pro Glu Ile Ile Lys Thr Gly 770 775 780 Phe Gly Asp Arg Asn Gly Tyr Asn Gln Ala Leu Ser Glu Leu Glu Asn 785 790 795 800 Glu Ile Tyr Gln Leu Pro Pro Arg Ser Ala * 805 810 <210> 1384 <211> 95 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6100..6384) <400> 1384 Met Glu Ala Lys Glu Cys Lys Val Gln Asp Ile Leu Thr Glu Asn Lys 1 5 10 15 Lys Phe Ile Ile Pro Ser Tyr Gln Arg Pro Tyr Ser Trp Thr Val Asp 20 25 30 Asn Ala Glu Gln Leu Ile Asp Asp Ile Tyr Lys Ser Ser Gln Ser Glu 35 40 45 Glu Asn Gly Tyr Phe Ile Gly Ser Met Ile Cys Ile Asn Lys Gly Gln 50 55 60 Asn Gln Tyr Glu Val Val Asp Gly Gln Gln Arg Leu Thr Thr Leu Ser 65 70 75 80 Ile Ile Val Ser Glu Leu Lys Lys Ser Ser Arg Phe Arg Gly * 85 90 <210> 1385 <211> 453 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6393..7751) <400> 1385 Leu Gln Lys Arg Val Leu Pro Ile Asp Val Tyr Ser Asp Glu Thr Asp 1 5 10 15 Glu Pro Arg Leu Ile Val Arg Lys Lys Glu His Asp Leu Tyr Lys Tyr 20 25 30 Tyr Ile Leu Gln Asp Ser Lys Asp Tyr Lys Pro Glu Lys Pro Ser Asp 35 40 45 Thr Glu Leu Val Phe Ile Ser Asn Ala Glu Thr Ile Arg Asp Tyr Leu 50 55 60 Leu Arg Leu Ser Val Asp Glu Leu Lys Leu Leu Ala Lys Tyr Ile Leu 65 70 75 80 Gln Asn Val Tyr Ile Val Phe Val Gln Thr Asp Asp Phe Ala Ser Ser 85 90 95 Phe Arg Leu Phe Asn Val Leu Asn Ser Arg Gly Leu Pro Leu Ser Asn 100 105 110 Ala Asp Leu Leu Lys Asn Ala Leu Phe Glu Ser Ala Ser Thr His Asn 115 120 125 Lys Lys Ser Glu Gln Ile Glu Ser Ala Trp Ser Gln Ile Glu Asp Met 130 135 140 Val Gly Val Arg Arg Leu Asp Lys Phe Leu Thr Leu His Lys Leu Ser 145 150 155 160 Glu Lys Lys Asp Arg Asp Arg Val Leu Gln Lys Gly Phe Glu Ala Phe 165 170 175 Ile Glu Asn Leu Gln Gln Gln Phe Asp Gly Asp Ala Ile Ala Met Ser 180 185 190 Leu Met Leu Val Asn Ser Ala Lys Asn Tyr Thr Lys Ile Leu Glu Asn 195 200 205 Asp Phe Glu His Pro Ser Ile Arg Arg Lys Ile Ala Ser Leu Ser Asn 210 215 220 Leu Gly Val Asp Glu Trp Ile Pro Pro Val Met Ala Phe Met Asn Arg 225 230 235 240 Met Ala Arg Thr Glu Asp Phe Asn Leu Asp Asp Phe Ser Gln Phe Ile 245 250 255 Thr Ala Phe Glu Lys Val Tyr Met His Gly Trp Leu Lys Lys Gln Ile 260 265 270 Lys Ser Gln Arg Glu Met Val Cys Tyr Ser Ala Leu Val Ala Ile Asn 275 280 285 Asn Asp Met Pro Phe Asp Ser Val Ile Asn Gln Ile Asn Gln His Ala 290 295 300 Asp Asn Ser Gly Phe Ile Ala Ala Leu Asp Glu Asp Leu Tyr Glu Pro 305 310 315 320 Arg Pro Asn Gln Val Asn Leu Ile Lys Ala Ile Leu Leu Arg Leu Asp 325 330 335 Met Glu Gln Gln Asp Glu Ser Val Ile Lys Thr Tyr Thr Gly Arg Ile 340 345 350 Thr Ile Glu His Ile Leu Pro Gln Ala Leu Val Asn Glu Tyr Trp Ile 355 360 365 Asn Arg Phe Gln Pro Gln Glu His Val Tyr Trp Leu His Lys Ile Gly 370 375 380 Asn Leu Thr Leu Ile Ser Gly Ser Lys Asn Ser Glu Ala Gln His Tyr 385 390 395 400 Asp Phe Ile Lys Lys Lys Ser Ile Tyr Glu Lys Leu Asn Ser Lys Ser 405 410 415 Ser Phe Asp Leu Thr Lys Asp Val Cys Asn Ser Ser Glu Trp Gly Leu 420 425 430 Ala Glu Leu Lys Met Arg His Glu Lys Met Lys Thr Gln Leu Lys Lys 435 440 445 Leu Trp Leu Val * 450 <210> 1386 <211> 7409 <212> DNA <213> Escherichia coli O157:H7 <400> 1386 ggctaaagtc agattgatcg cattctaaca gccgaaaaca gggaggcaat ggttattagt 60 gtggggaaat gttcgcacca gagcagaact ctggtgcgat gaggagggaa tgacgtttta 120 cttattcgta ggtaaaggag aaggtcgcgt tacctgaaaa tgttccaaca ccgacagcat 180 taccgctacc atccggtacc agctgcgccg taaaaggtaa aaacagcagg ttgtttgacc 240 aggcggcgaa gttgtagtca accgtgttgc taccatctgc ttttaacaat actttgctat 300 tgtcataagt tgaatttact tttacagcca cgcctgaagc cgagccagtc gttttaccca 360 ccagtgtggc atcgctgggt ttatttgccg ctttcaactt aaccgtaatt ttactggcat 420 aacagtattc agcacggata gaaaaaggga tttcccgcgt aagcccattt ttcacttccg 480 aaacatagct gttcccaagc gttacctgat tgccactgac gttgccctga tcttgtgcca 540 gggcaactgt tgcacaggtc ggttcatcga cgaaaaactt taaagagtca ttgtcaatgt 600 aaaagttgat ccacggctgg tcattggtac ctatatacca tgacgcaatc tttcctgcta 660 tcgttgttcc gctggaaaca ccattcttgg gtttaaattc aggagttatg aataagcgaa 720 aacgtaaata ccaactttga tcactgtact cataggccca tttcgtctgg gtgcttggta 780 tgaagttatc tgcgccactt tgtgcaggta gccataaatc aagttcatct gcggcaccac 840 aactaaggca taataactcg acagaataca caatgcctgg aacagttgtt tttaataacg 900 ctgcgccatt cgttgtggtg tacgtggata ttaaacttgg gtcagctgta ttaagaaagt 960 gaactgcctt actatcccca agagatttac accctatggc atcgcctctt agttgaatat 1020 ttacatccca tgtagcttcg gctatttctg tcggaacctc gaccatttgt gacgccagac 1080 taagctgagt agagcttatc ttcatgtgat aatccccttc agcatttctc tctatataac 1140 attcattcgc caatgcatac caggatgtgg taaaaaatag cagtatcaca ctgcataact 1200 gaatcaacag tttattgcct ttcctttgca taattatcct tattattcgt aagatacgtt 1260 aacaataacc tggcttctca ccattcccga ttcaggagga agggcattat tcacccgctg 1320 catacgggaa taaaaggtcc aggttgaggg aacagcattg ccaggtgcta ccgaataaat 1380 tgctgttgag gaaccatccg ttcctcgcac gttaaatgtc tgctgattcg gttgggccga 1440 aaaaatcaca atgccgacgt ttttcgcccc ggtagcctgc tgttcatatt cattactaaa 1500 aatttgatta ttcgcctgtg caagcgatcc cgcctgcggc tgaaaatcta atttcatttg 1560 cgactgtgtc gtttgaatgt tatcgcaaga gaccacattc acattaaacg ttttgccacc 1620 cgcataatcc gttgtcgggg ttacattgtc ggcaaaatag tccagcgtca ctgtgccgag 1680 atcgacaacg ccattattac tgacttcaac ctgacaggtg ctgggcacga tctttgcggt 1740 gagatccaca tcctggccgg aataggcaaa aggcgtgata agggctgttg ccagccctaa 1800 aaagtgtacg attttatgat gcctgcatag cattctaata tccttatccg ctattactga 1860 taagtgatcg tgaaagtcgt gggagagcgg aaattacccg gtcttacatc ggttaccaat 1920 ctaccttccg caacggtcat ccgtgcactt aacgggtaat cgtaaggctg agttgtggtg 1980 tcggcgggaa gcgtcacagg cactggtatc ttttgagcac aatggaattg cgtactgcca 2040 ttgctttccg gtgtatctgt agtccatact tccacagccg ttctggttgc tgcgctagcg 2100 tcagtaaact tgttagaaaa acccgccgat gacgattgag aaccagcaca ggatatacca 2160 ttaggtgcca gcactatttg ggcgctgttt tggggaaggc cagagcaatt gctaaagcga 2220 attttaaact gttgcacttt gctttttgca ccgagttcag aaatataaac attgccaaag 2280 accacttcat tgatcacttt attactatta tccattatct gagcactgca ggtacccata 2340 gtcaggttac tgtttacggt taaagaagcg gacgttgtac tcgcagaagc aaaattgctg 2400 ttaaagctta cacccacggc aacagtagca atcagtgtag cgatgacttt taatttcatg 2460 gtggctgtcc ctgttattcg taggtgaagt taaaggtggc ttttgcctga aacgcaccgg 2520 tgcgtcctgc tcccgccgtt gtttcgcgca gtgctacggt cagaggcaca ccgctggctt 2580 tctcatcggc gctccattca aatttgtcag tattattggg tgtgaagaaa gtcgagtctg 2640 cggtatctct acgcttaatc cccatcccca ccccagcagc gccagaggtt gcttcattaa 2700 caattaactt accggaaacc gttgttcctg taagtgtggt aaaaatcttt gagtaaccat 2760 tgctgcaatc ggaggccttt aatttaaagt tggcctgagc ttcgggcgca gcggtagcga 2820 ctttatccag accaacatca ggaattgtca ggctgtattc atcgttacta ccggtcactg 2880 ctggaccacc atcttccact atagttatcg tgcaggtggt ggctaatacg gtggccgtaa 2940 aatcgacatt aagatctgtt gcagagccaa ccgccggtaa acccaggcct attaacgcgg 3000 atgttagtag tatccttttc atagaatttt ccatattagt gatttgctac ctgacaggta 3060 agattgttaa gtaataaggt gttggtgctt ccctgcgttt gtggctgcgc cgggaactgg 3120 tagtgcaact tacagtcaat ggtttggttg ttttcatacc agcgcacgat taattccccg 3180 ctgtcgttaa taccgcgtac aaatgcctga ccaccctggc ccatgctgcc gatcatcacc 3240 tcaccctggt aaacctccgc agcaaacgga atggatttgc cattggcggc agtaatattc 3300 agcacggcag aacgcccctc gtcagtttcg aaacgggtca aaacaacgga gccgctacgt 3360 ggtacggtgg tggcgctggt acttttcagt tcaacatcgt tttccagtgt ttcaatgttc 3420 agacctaccc ggttttcacg atatgggctg acagaggacg tcacggcata tccccagcga 3480 tcgatttcgt tattactgtt attgattcgt gcgcctttag cacctagggc gttgattaac 3540 accagcgtgt cgttactgct gaaactgttg ttagtgaacg ttaaaccacc actgtgtaat 3600 acaaagccgc catcggttga gatggagtac tgttggctgt tatcagaagt ggccgaggcc 3660 gaagcggaaa taccgcctaa cccagattca tagttgagat aaccaccaac agaggctaaa 3720 tcgccggcgt ttttatcgag gctataacct gcgttgacac tgtagttcac cagattgttt 3780 tcagtgttac cggaactgtt aacattcaac tgatgtgaac catcgaaatc ggtattgagc 3840 tgagtattta aattgcggaa accagaagac ttacgtttgc cacctaaaat attctcaata 3900 ggtacgctaa cgctgacgta catcgcgtca tctttctcgc cgtcttcatt ccagctacgt 3960 tgtaggttga cgctgaaact gccccacgaa acgcttttac tgtaaccaac attatattca 4020 gtgcggctat tgttcgccgc ccagtaatac gtccagctac cggaaataaa cagcgaaccg 4080 taatcttcat aggcgatatt caatggctgg ttaatgctga cggtaaactg gtttttcata 4140 cgtgagtacg tctgcatggt gtttttgtct tcatcggcag acaaatgctt ggcgtcgtca 4200 atgaggacta acgcatcatg caggcccagg taatcctggg tggaatagcg gtacgccgcg 4260 aggttaaatg atgtcccggt atcctggaaa agtttgttcc aggtcacgcg ataactttgc 4320 ccctggtagg ttttatcatc cggaatttca gcacgggaat gggtaacgtc taccgcaaag 4380 gcgccgatgc tggtgttgat acccacacct aacagcccgg caagatagtt attatcggtg 4440 aactgaatgc cggtataacc cgtgaagagg ttattcagac catagtaata agaggcttgc 4500 cccatattgg gttcggatcg cagactgtca tcaatgactt tacccgcgct gaaatcccaa 4560 cggcccacac caggacgttg catttgtaca accgacgaga agggttgcgt aaaggtgcgt 4620 ttggaaccat ccgcttcttc aatggtcacg accagttcgc taccaaagcc ggaagggcta 4680 atgtcgtcta taacaaattc accgggcgga acggtggttt cataaatttt atatccgctt 4740 tgcgtcacgg tgactttggc gttggagttt gctacaccgc ggatggtcgg agcgtaactg 4800 gccagcgccg aaggcagcat acggctgtcg ctgtacaggc gaacaccacg gacgttgaca 4860 gagtcaaacg tttcaccggt ggtataggca tcacccataa ttatctggga acggattgcc 4920 ggaatgtcac gctgtaagta acgatcctgg aaatcgaaat cgctgccgtt atctgttgtc 4980 cagttatagt taccgcgcgc acgaaagtgc caggctccta aattgatacc tgagttgaac 5040 gcgccataga cgctgtcact attgtcgtta tctgaacttg tgtgatacgc gttcagggta 5100 tatgccagtg tggcagcgtt aattcccgat tcccataaag aagggtcaac gtagccgcca 5160 tagcttttca gaacataggc ctgagggatc gtcagatcga gaaactggtc actaccgtca 5220 aagcacacat ccgccttttc gtatgacttt gccagatcca gacaatcctc ttcttcacct 5280 tctctggcga gtaaagtgac aggctgttca ggttgcttaa tgtgaagttg cgccaggttt 5340 ttatgggtaa gacaggccgc cgcactgttt tcgccaatat ccacaaacgg aatttctaag 5400 ctggaagtcg cctgaccgtt tacaaatacg cggacattat agagacccgg cggtgtcggg 5460 ttgccttgag cataacgttt aacatcaatc gttgatgcgc cagttcccat taaaaaggaa 5520 ctgtcatatt ccacggtgtc cgccgcagca ccgttgctgc tataaaacag ggcacaacag 5580 gccgcaagta gcgttttttt cgggatacgg cttttttgat gagtaaactg gtacaaggtt 5640 gcattcctgg cgatgttaaa aagaatccgt ttatttttta gaatgttgcg gaaccatcaa 5700 tgttgccgcc aaagtcgttg atcgctttaa agaccacttt tccggatgac acgcttcctg 5760 gcagactggt tacgccaaag cttgcctggc tgaacggcgt gaccatgctg gaattgacgt 5820 tgtaggtttt gccgccgctt tccagcttga cctcattaaa ggacacgtaa tatggcgttg 5880 ggttatttgc ctgtaactga gcgttgttta atttccaggt gattttcgcc ggtgcttcag 5940 ccggttctcc ctgtaaccca ctcgggcgat aaaagagttt gatgcgtgtg cggaaagcca 6000 gctgtaacaa gtttttgtca gcctcagcat ctttcggctt aggcggcact tccagcacgt 6060 taaaccagta gacgctttca cggtctttcg gcagggctgt tgcaccggta tacatcactt 6120 ttacggtttg accgcgtttt ggctccacgc gtgaaactgg tggggtcgcg gtaaacggca 6180 ctttgatctg gctgggatcg gcattgtcat cgcccgtatc caaccagttc tgaatcagta 6240 aggggcgatt ccctttattt tccagacgaa cgttaacatc ttttttatca gcgttataaa 6300 tgatacgtgt tccggaaata ataatgtcag cgaatgctgg tgcactggct aacagagtac 6360 tcacaaataa tgcactaacc gtttttttaa ccaagggaaa cataagcact ccttgctgtc 6420 tgtagaaaga ttaaattcgc gaaaataagg tttgcctgct ggcaaatctt atgctcaaca 6480 caccatcaat tacttataag caacggtgta cagcgcgtta gtggttacat gaccagcagt 6540 tacagccggg ctgttcggtg ctttaacgta agatgcgtta aatacgtact ggcctttacc 6600 ttctgcgtct aatgtcagtt cctgaacttc agaagagttg ttcatatgga cctgcttaat 6660 ttcagcagcg ccagctttgt ttttcatgtt atgaactgca atgtttacgt tctgagccgg 6720 tgcaataccg ttaacagtga tgttcatatt gttattcagg gtaccgctgg tgttcgcgta 6780 acttgcagaa cccatagtta actcagcatt cttcggagca cctggatcac actcaacaga 6840 aatcatgaac tctttcggca gtaaaccgac agcagttgcg ctaacttcag caaaagtatc 6900 agtaacattc gcagtatcca gggtaaccac gccatcagtg gtaacgctat gcataccagt 6960 atctaccaca cccactttac aggtaccgga ctgtaccata ccgttaaagt cgatatgacc 7020 accatctaca gccagggcgg aaccagaagc cataaccaga gcggctgcga gaagtgcttt 7080 tttcattaca tgcatcctta caaaaattat atgaaattaa tattgcgagc ggatattact 7140 caaagttttt ggaggatgta ataggggtga attatcacgg gtgtgaatat atttacgtgg 7200 tgtattgaat tgttgctatt ctaggttttt taaacaaaaa atgcctaatc tatttgcatg 7260 aagtgctatt tcatgaatta attaaaaaaa actaaaatgt aaattaagta tatttaatct 7320 gtaagagggg aagtgaggag taagataaga aaataaaata atacagctaa taccagatgg 7380 caggttgtag tactgctagc gaagtgagt 7409 <210> 1387 <211> 370 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(122..1231) <400> 1387 Met Gln Arg Lys Gly Asn Lys Leu Leu Ile Gln Leu Cys Ser Val Ile 1 5 10 15 Leu Leu Phe Phe Thr Thr Ser Trp Tyr Ala Leu Ala Asn Glu Cys Tyr 20 25 30 Ile Glu Arg Asn Ala Glu Gly Asp Tyr His Met Lys Ile Ser Ser Thr 35 40 45 Gln Leu Ser Leu Ala Ser Gln Met Val Glu Val Pro Thr Glu Ile Ala 50 55 60 Glu Ala Thr Trp Asp Val Asn Ile Gln Leu Arg Gly Asp Ala Ile Gly 65 70 75 80 Cys Lys Ser Leu Gly Asp Ser Lys Ala Val His Phe Leu Asn Thr Ala 85 90 95 Asp Pro Ser Leu Ile Ser Thr Tyr Thr Thr Thr Asn Gly Ala Ala Leu 100 105 110 Leu Lys Thr Thr Val Pro Gly Ile Val Tyr Ser Val Glu Leu Leu Cys 115 120 125 Leu Ser Cys Gly Ala Ala Asp Glu Leu Asp Leu Trp Leu Pro Ala Gln 130 135 140 Ser Gly Ala Asp Asn Phe Ile Pro Ser Thr Gln Thr Lys Trp Ala Tyr 145 150 155 160 Glu Tyr Ser Asp Gln Ser Trp Tyr Leu Arg Phe Arg Leu Phe Ile Thr 165 170 175 Pro Glu Phe Lys Pro Lys Asn Gly Val Ser Ser Gly Thr Thr Ile Ala 180 185 190 Gly Lys Ile Ala Ser Trp Tyr Ile Gly Thr Asn Asp Gln Pro Trp Ile 195 200 205 Asn Phe Tyr Ile Asp Asn Asp Ser Leu Lys Phe Phe Val Asp Glu Pro 210 215 220 Thr Cys Ala Thr Val Ala Leu Ala Gln Asp Gln Gly Asn Val Ser Gly 225 230 235 240 Asn Gln Val Thr Leu Gly Asn Ser Tyr Val Ser Glu Val Lys Asn Gly 245 250 255 Leu Thr Arg Glu Ile Pro Phe Ser Ile Arg Ala Glu Tyr Cys Tyr Ala 260 265 270 Ser Lys Ile Thr Val Lys Leu Lys Ala Ala Asn Lys Pro Ser Asp Ala 275 280 285 Thr Leu Val Gly Lys Thr Thr Gly Ser Ala Ser Gly Val Ala Val Lys 290 295 300 Val Asn Ser Thr Tyr Asp Asn Ser Lys Val Leu Leu Lys Ala Asp Gly 305 310 315 320 Ser Asn Thr Val Asp Tyr Asn Phe Ala Ala Trp Ser Asn Asn Leu Leu 325 330 335 Phe Leu Pro Phe Thr Ala Gln Leu Val Pro Asp Gly Ser Gly Asn Ala 340 345 350 Val Gly Val Gly Thr Phe Ser Gly Asn Ala Thr Phe Ser Phe Thr Tyr 355 360 365 Glu * <210> 1388 <211> 197 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1243..1833) <400> 1388 Met Leu Cys Arg His His Lys Ile Val His Phe Leu Gly Leu Ala Thr 1 5 10 15 Ala Leu Ile Thr Pro Phe Ala Tyr Ser Gly Gln Asp Val Asp Leu Thr 20 25 30 Ala Lys Ile Val Pro Ser Thr Cys Gln Val Glu Val Ser Asn Asn Gly 35 40 45 Val Val Asp Leu Gly Thr Val Thr Leu Asp Tyr Phe Ala Asp Asn Val 50 55 60 Thr Pro Thr Thr Asp Tyr Ala Gly Gly Lys Thr Phe Asn Val Asn Val 65 70 75 80 Val Ser Cys Asp Asn Ile Gln Thr Thr Gln Ser Gln Met Lys Leu Asp 85 90 95 Phe Gln Pro Gln Ala Gly Ser Leu Ala Gln Ala Asn Asn Gln Ile Phe 100 105 110 Ser Asn Glu Tyr Glu Gln Gln Ala Thr Gly Ala Lys Asn Val Gly Ile 115 120 125 Val Ile Phe Ser Ala Gln Pro Asn Gln Gln Thr Phe Asn Val Arg Gly 130 135 140 Thr Asp Gly Ser Ser Thr Ala Ile Tyr Ser Val Ala Pro Gly Asn Ala 145 150 155 160 Val Pro Ser Thr Trp Thr Phe Tyr Ser Arg Met Gln Arg Val Asn Asn 165 170 175 Ala Leu Pro Pro Glu Ser Gly Met Val Arg Ser Gln Val Ile Val Asn 180 185 190 Val Ser Tyr Glu * 195 <210> 1389 <211> 202 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1854..2459) <400> 1389 Met Lys Leu Lys Val Ile Ala Thr Leu Ile Ala Thr Val Ala Val Gly 1 5 10 15 Val Ser Phe Asn Ser Asn Phe Ala Ser Ala Ser Thr Thr Ser Ala Ser 20 25 30 Leu Thr Val Asn Ser Asn Leu Thr Met Gly Thr Cys Ser Ala Gln Ile 35 40 45 Met Asp Asn Ser Asn Lys Val Ile Asn Glu Val Val Phe Gly Asn Val 50 55 60 Tyr Ile Ser Glu Leu Gly Ala Lys Ser Lys Val Gln Gln Phe Lys Ile 65 70 75 80 Arg Phe Ser Asn Cys Ser Gly Leu Pro Gln Asn Ser Ala Gln Ile Val 85 90 95 Leu Ala Pro Asn Gly Ile Ser Cys Ala Gly Ser Gln Ser Ser Ser Ala 100 105 110 Gly Phe Ser Asn Lys Phe Thr Asp Ala Ser Ala Ala Thr Arg Thr Ala 115 120 125 Val Glu Val Trp Thr Thr Asp Thr Pro Glu Ser Asn Gly Ser Thr Gln 130 135 140 Phe His Cys Ala Gln Lys Ile Pro Val Pro Val Thr Leu Pro Ala Asp 145 150 155 160 Thr Thr Thr Gln Pro Tyr Asp Tyr Pro Leu Ser Ala Arg Met Thr Val 165 170 175 Ala Glu Gly Arg Leu Val Thr Asp Val Arg Pro Gly Asn Phe Arg Ser 180 185 190 Pro Thr Thr Phe Thr Ile Thr Tyr Gln * 195 200 <210> 1390 <211> 187 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2474..3034) <400> 1390 Met Glu Asn Ser Met Lys Arg Ile Leu Leu Thr Ser Ala Leu Ile Gly 1 5 10 15 Leu Gly Leu Pro Ala Val Gly Ser Ala Thr Asp Leu Asn Val Asp Phe 20 25 30 Thr Ala Thr Val Leu Ala Thr Thr Cys Thr Ile Thr Ile Val Glu Asp 35 40 45 Gly Gly Pro Ala Val Thr Gly Ser Asn Asp Glu Tyr Ser Leu Thr Ile 50 55 60 Pro Asp Val Gly Leu Asp Lys Val Ala Thr Ala Ala Pro Glu Ala Gln 65 70 75 80 Ala Asn Phe Lys Leu Lys Ala Ser Asp Cys Ser Asn Gly Tyr Ser Lys 85 90 95 Ile Phe Thr Thr Leu Thr Gly Thr Thr Val Ser Gly Lys Leu Ile Val 100 105 110 Asn Glu Ala Thr Ser Gly Ala Ala Gly Val Gly Met Gly Ile Lys Arg 115 120 125 Arg Asp Thr Ala Asp Ser Thr Phe Phe Thr Pro Asn Asn Thr Asp Lys 130 135 140 Phe Glu Trp Ser Ala Asp Glu Lys Ala Ser Gly Val Pro Leu Thr Val 145 150 155 160 Ala Leu Arg Glu Thr Thr Ala Gly Ala Gly Arg Thr Gly Ala Phe Gln 165 170 175 Ala Lys Ala Thr Phe Asn Phe Thr Tyr Glu * 180 185 <210> 1391 <211> 867 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3036..5636) <400> 1391 Leu Tyr Gln Phe Thr His Gln Lys Ser Arg Ile Pro Lys Lys Thr Leu 1 5 10 15 Leu Ala Ala Cys Cys Ala Leu Phe Tyr Ser Ser Asn Gly Ala Ala Ala 20 25 30 Asp Thr Val Glu Tyr Asp Ser Ser Phe Leu Met Gly Thr Gly Ala Ser 35 40 45 Thr Ile Asp Val Lys Arg Tyr Ala Gln Gly Asn Pro Thr Pro Pro Gly 50 55 60 Leu Tyr Asn Val Arg Val Phe Val Asn Gly Gln Ala Thr Ser Ser Leu 65 70 75 80 Glu Ile Pro Phe Val Asp Ile Gly Glu Asn Ser Ala Ala Ala Cys Leu 85 90 95 Thr His Lys Asn Leu Ala Gln Leu His Ile Lys Gln Pro Glu Gln Pro 100 105 110 Val Thr Leu Leu Ala Arg Glu Gly Glu Glu Glu Asp Cys Leu Asp Leu 115 120 125 Ala Lys Ser Tyr Glu Lys Ala Asp Val Cys Phe Asp Gly Ser Asp Gln 130 135 140 Phe Leu Asp Leu Thr Ile Pro Gln Ala Tyr Val Leu Lys Ser Tyr Gly 145 150 155 160 Gly Tyr Val Asp Pro Ser Leu Trp Glu Ser Gly Ile Asn Ala Ala Thr 165 170 175 Leu Ala Tyr Thr Leu Asn Ala Tyr His Thr Ser Ser Asp Asn Asp Asn 180 185 190 Ser Asp Ser Val Tyr Gly Ala Phe Asn Ser Gly Ile Asn Leu Gly Ala 195 200 205 Trp His Phe Arg Ala Arg Gly Asn Tyr Asn Trp Thr Thr Asp Asn Gly 210 215 220 Ser Asp Phe Asp Phe Gln Asp Arg Tyr Leu Gln Arg Asp Ile Pro Ala 225 230 235 240 Ile Arg Ser Gln Ile Ile Met Gly Asp Ala Tyr Thr Thr Gly Glu Thr 245 250 255 Phe Asp Ser Val Asn Val Arg Gly Val Arg Leu Tyr Ser Asp Ser Arg 260 265 270 Met Leu Pro Ser Ala Leu Ala Ser Tyr Ala Pro Thr Ile Arg Gly Val 275 280 285 Ala Asn Ser Asn Ala Lys Val Thr Val Thr Gln Ser Gly Tyr Lys Ile 290 295 300 Tyr Glu Thr Thr Val Pro Pro Gly Glu Phe Val Ile Asp Asp Ile Ser 305 310 315 320 Pro Ser Gly Phe Gly Ser Glu Leu Val Val Thr Ile Glu Glu Ala Asp 325 330 335 Gly Ser Lys Arg Thr Phe Thr Gln Pro Phe Ser Ser Val Val Gln Met 340 345 350 Gln Arg Pro Gly Val Gly Arg Trp Asp Phe Ser Ala Gly Lys Val Ile 355 360 365 Asp Asp Ser Leu Arg Ser Glu Pro Asn Met Gly Gln Ala Ser Tyr Tyr 370 375 380 Tyr Gly Leu Asn Asn Leu Phe Thr Gly Tyr Thr Gly Ile Gln Phe Thr 385 390 395 400 Asp Asn Asn Tyr Leu Ala Gly Leu Leu Gly Val Gly Ile Asn Thr Ser 405 410 415 Ile Gly Ala Phe Ala Val Asp Val Thr His Ser Arg Ala Glu Ile Pro 420 425 430 Asp Asp Lys Thr Tyr Gln Gly Gln Ser Tyr Arg Val Thr Trp Asn Lys 435 440 445 Leu Phe Gln Asp Thr Gly Thr Ser Phe Asn Leu Ala Ala Tyr Arg Tyr 450 455 460 Ser Thr Gln Asp Tyr Leu Gly Leu His Asp Ala Leu Val Leu Ile Asp 465 470 475 480 Asp Ala Lys His Leu Ser Ala Asp Glu Asp Lys Asn Thr Met Gln Thr 485 490 495 Tyr Ser Arg Met Lys Asn Gln Phe Thr Val Ser Ile Asn Gln Pro Leu 500 505 510 Asn Ile Ala Tyr Glu Asp Tyr Gly Ser Leu Phe Ile Ser Gly Ser Trp 515 520 525 Thr Tyr Tyr Trp Ala Ala Asn Asn Ser Arg Thr Glu Tyr Asn Val Gly 530 535 540 Tyr Ser Lys Ser Val Ser Trp Gly Ser Phe Ser Val Asn Leu Gln Arg 545 550 555 560 Ser Trp Asn Glu Asp Gly Glu Lys Asp Asp Ala Met Tyr Val Ser Val 565 570 575 Ser Val Pro Ile Glu Asn Ile Leu Gly Gly Lys Arg Lys Ser Ser Gly 580 585 590 Phe Arg Asn Leu Asn Thr Gln Leu Asn Thr Asp Phe Asp Gly Ser His 595 600 605 Gln Leu Asn Val Asn Ser Ser Gly Asn Thr Glu Asn Asn Leu Val Asn 610 615 620 Tyr Ser Val Asn Ala Gly Tyr Ser Leu Asp Lys Asn Ala Gly Asp Leu 625 630 635 640 Ala Ser Val Gly Gly Tyr Leu Asn Tyr Glu Ser Gly Leu Gly Gly Ile 645 650 655 Ser Ala Ser Ala Ser Ala Thr Ser Asp Asn Ser Gln Gln Tyr Ser Ile 660 665 670 Ser Thr Asp Gly Gly Phe Val Leu His Ser Gly Gly Leu Thr Phe Thr 675 680 685 Asn Asn Ser Phe Ser Ser Asn Asp Thr Leu Val Leu Ile Asn Ala Leu 690 695 700 Gly Ala Lys Gly Ala Arg Ile Asn Asn Ser Asn Asn Glu Ile Asp Arg 705 710 715 720 Trp Gly Tyr Ala Val Thr Ser Ser Val Ser Pro Tyr Arg Glu Asn Arg 725 730 735 Val Gly Leu Asn Ile Glu Thr Leu Glu Asn Asp Val Glu Leu Lys Ser 740 745 750 Thr Ser Ala Thr Thr Val Pro Arg Ser Gly Ser Val Val Leu Thr Arg 755 760 765 Phe Glu Thr Asp Glu Gly Arg Ser Ala Val Leu Asn Ile Thr Ala Ala 770 775 780 Asn Gly Lys Ser Ile Pro Phe Ala Ala Glu Val Tyr Gln Gly Glu Val 785 790 795 800 Met Ile Gly Ser Met Gly Gln Gly Gly Gln Ala Phe Val Arg Gly Ile 805 810 815 Asn Asp Ser Gly Glu Leu Ile Val Arg Trp Tyr Glu Asn Asn Gln Thr 820 825 830 Ile Asp Cys Lys Leu His Tyr Gln Phe Pro Ala Gln Pro Gln Thr Gln 835 840 845 Gly Ser Thr Asn Thr Leu Leu Leu Asn Asn Leu Thr Cys Gln Val Ala 850 855 860 Asn His * 865 <210> 1392 <211> 242 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5678..6403) <400> 1392 Met Phe Pro Leu Val Lys Lys Thr Val Ser Ala Leu Phe Val Ser Thr 1 5 10 15 Leu Leu Ala Ser Ala Pro Ala Phe Ala Asp Ile Ile Ile Ser Gly Thr 20 25 30 Arg Ile Ile Tyr Asn Ala Asp Lys Lys Asp Val Asn Val Arg Leu Glu 35 40 45 Asn Lys Gly Asn Arg Pro Leu Leu Ile Gln Asn Trp Leu Asp Thr Gly 50 55 60 Asp Asp Asn Ala Asp Pro Ser Gln Ile Lys Val Pro Phe Thr Ala Thr 65 70 75 80 Pro Pro Val Ser Arg Val Glu Pro Lys Arg Gly Gln Thr Val Lys Val 85 90 95 Met Tyr Thr Gly Ala Thr Ala Leu Pro Lys Asp Arg Glu Ser Val Tyr 100 105 110 Trp Phe Asn Val Leu Glu Val Pro Pro Lys Pro Lys Asp Ala Glu Ala 115 120 125 Asp Lys Asn Leu Leu Gln Leu Ala Phe Arg Thr Arg Ile Lys Leu Phe 130 135 140 Tyr Arg Pro Ser Gly Leu Gln Gly Glu Pro Ala Glu Ala Pro Ala Lys 145 150 155 160 Ile Thr Trp Lys Leu Asn Asn Ala Gln Leu Gln Ala Asn Asn Pro Thr 165 170 175 Pro Tyr Tyr Val Ser Phe Asn Glu Val Lys Leu Glu Ser Gly Gly Lys 180 185 190 Thr Tyr Asn Val Asn Ser Ser Met Val Thr Pro Phe Ser Gln Ala Ser 195 200 205 Phe Gly Val Thr Ser Leu Pro Gly Ser Val Ser Ser Gly Lys Val Val 210 215 220 Phe Lys Ala Ile Asn Asp Phe Gly Gly Asn Ile Asp Gly Ser Ala Thr 225 230 235 240 Phe * <210> 1393 <211> 199 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6490..7086) <400> 1393 Met Lys Lys Ala Leu Leu Ala Ala Ala Leu Val Met Ala Ser Gly Ser 1 5 10 15 Ala Leu Ala Val Asp Gly Gly His Ile Asp Phe Asn Gly Met Val Gln 20 25 30 Ser Gly Thr Cys Lys Val Gly Val Val Asp Thr Gly Met His Ser Val 35 40 45 Thr Thr Asp Gly Val Val Thr Leu Asp Thr Ala Asn Val Thr Asp Thr 50 55 60 Phe Ala Glu Val Ser Ala Thr Ala Val Gly Leu Leu Pro Lys Glu Phe 65 70 75 80 Met Ile Ser Val Glu Cys Asp Pro Gly Ala Pro Lys Asn Ala Glu Leu 85 90 95 Thr Met Gly Ser Ala Ser Tyr Ala Asn Thr Ser Gly Thr Leu Asn Asn 100 105 110 Asn Met Asn Ile Thr Val Asn Gly Ile Ala Pro Ala Gln Asn Val Asn 115 120 125 Ile Ala Val His Asn Met Lys Asn Lys Ala Gly Ala Ala Glu Ile Lys 130 135 140 Gln Val His Met Asn Asn Ser Ser Glu Val Gln Glu Leu Thr Leu Asp 145 150 155 160 Ala Glu Gly Lys Gly Gln Tyr Val Phe Asn Ala Ser Tyr Val Lys Ala 165 170 175 Pro Asn Ser Pro Ala Val Thr Ala Gly His Val Thr Thr Asn Ala Leu 180 185 190 Tyr Thr Val Ala Tyr Lys * 195 <210> 1394 <211> 7398 <212> DNA <213> Escherichia coli O157:H7 <400> 1394 atcagtcacg ctggtttgag atacagaaca ccaggtgtct gatgagtaag cgtctattcc 60 ctatgaataa tttatgtcgt tattcgtcct gtcatccacc ctctgtatgg ttaagcctgg 120 gttatatttt gtacaatatc gggataccgt tcgaaccaat ccagaatatt acgcatcgcg 180 tcactgatgt ttttatcgtc tttatattga ttctcaagtc tattatttcg aacaatagta 240 agcttagaac gtattttatc atcacaatcg acaattttcg cattcaatgc atttacttca 300 tcctgcactt ctatactatt ccaattgtcc cttttgttat caaataaagt ccttttatcc 360 tctaatgatt tattacgact tatgattaac tctttaattt ctcgcaataa gtcatcgtaa 420 tctttaatgg aagctcttat ttcctgatag ttttttagta aatcctccca gttaattgca 480 aatgcactgg aaaaatagta aaaatcgcga gcatacttat tgagccttga gtcgtaatct 540 gtcttaaacg attttatatg ttccagttgg tttgatagtg ctttaatttg tttttcttca 600 acaccttcaa aaatgggtgc aagttcctta taatcaaatg ttacatttgt agcagattct 660 ttatgagact cctttatttg cttttggaca tattcttttg gattttcagt aagtattgtt 720 ccatctggcg gcggaatcat tttatttatt atagattcaa caaacttaat ccggtcactt 780 tctatcatat tgttaatgat attttgtgca ttttcctgca tatctttaaa aataaaaaac 840 tcaaccctac tattatcaaa atgatatttt tcctcgtacg atttattttc aacataaagt 900 gttgataaaa acgactctaa ctctaaaaat gcgtttttat atttttcctt agtctttgac 960 tcggaattat aaaaatttat tacatcgata ttgatagcac ttaccttttt taagaaatca 1020 ggtatttgtt ctttacttat agctccgtcc agatccatat acatgtattt ttgcgctgta 1080 agaccatctt ttgaataatt tgtatttgga tcaatagcac agtctttgca cctatctcca 1140 ctgtaataat agcctaaatt tgccccaatc aaattactat ttttaaagaa gacattattg 1200 ttctctgtat ttttcttgct aaatgaagaa tcggtccctt tctttatact ctctacgcat 1260 ttcgaaaaat tatcatctaa cttaagattt ctcgatcttc tttcaatgta atcagaaaaa 1320 tactctttgg ggttaaacat agttctatct gaaccatctt cacgaagacc atcgtttatt 1380 ttaatatgct tcaaattaca attataaaac acagtccccg tatccggacc cctgatttca 1440 tcataattag acttgttgaa cgaatttgcc aaaaaatcca ttccatgagc atcaagccct 1500 attatattac agttataaaa atgactcaga agtatactcg agccaggaca acatcctccc 1560 tggattatac aatcctgaac gaaagactgc ataaagagat aagaacctaa tttttcttga 1620 atactatcag gttgtgtaac ggtgtagatt ttagacgtct cacatctata attttcaatt 1680 ttgcatttag aaataaaaca acctttaaac atacctttta ttggtttttt atttcctgat 1740 tccacagtat catcattagt ctcataaagc tgtatgttgt tgaatttaca atcatcgaaa 1800 tagcaatttt caaaaaccgg accttcaagg ttagggctgt ttatcactcc tgaaaaaatt 1860 acattcttaa aactacaata ttttaatgaa tttaaaacat ccttagacaa cgatgataaa 1920 ttgattgttg tattaataat aggaatttta tttttaatca gcgtcgcaag ttttacagaa 1980 taattatcaa acgttaatct caccaaggga gaattatcaa aatgtaaatc atcgagataa 2040 ttatcaagcg ttaatctctc tgaagaaacc tgtttttttt cgttatcatt cgaagtagcc 2100 cccgtgtaga gattaaagga tctactcaca ataacttcat tattttcatt tgtggtaaag 2160 tctgtcttag tactaaatcg ccattgttgt tctttttttg ccagagattt aatcttatcg 2220 aacacctcgg ctttattatc aactttcgtg acaaattcgt aaattaagcc tttgacttct 2280 ttaatatgag agccaggaaa aagatcgcga acaaactccc acagtgtacg ttttttaaat 2340 aaatcccctt tgccatcaag aatattttca atatccttag agtttacatt atatttctta 2400 tcattaatac ttaaagcaat tttatcagaa tagcctttat gactaagcct ctccttatac 2460 attgcttcta aaaaaggatt agtattaaca aaaacatctg gttttaattt agcgaccata 2520 aatcctccgg cgtgtaatat tgagttgttt gaaaaacaat aacttctatg ttgttaatta 2580 actgtactgc tagttaggtt agcaacaagt gttacttata ttaccggtga atactgtaaa 2640 aaatagctca ttatttccat tttaacccag ggtgttcacc ctggatttgc aattttttgg 2700 gggttaacgg tacattccac gggttaaccg cagcatcaga aaatgagcgt ttttttatag 2760 ccgcttttat tgtcgaggtt aaaataaaga gattttatta aattttatca aggtgattta 2820 tggataatct tattggcaca ccaccaaacc acgcagttcc ccataactat atagacatgg 2880 agcaaatgga atatttatgt catctcaatc gtttttctaa attgtctaac gattttttaa 2940 taaatggtcc aagagaggac ctttttacat ataaatatgt tttagatggt tcattttcaa 3000 atttacagca tttacttcct aaaggacaac tacagaagat acaacagaga ttaagttctc 3060 ttatgcataa aaacatgttt cattgttttc atgttttttt attaaaacta tgctcaattg 3120 agagtattcc tctcccaaat gccgattacg ctttctttga tgacgaaatg ccatttacat 3180 taactgatga acagatcgaa aatatttctt ttttaaacgc atatcacaaa gaaaagaaag 3240 gaaacaacga cattgttaca tttgatttca tgagcgctga tcaccactat aattttagca 3300 caaccatagc tttaacaaat gatagcttcc atatatcttc aataaacaac cataactcac 3360 aggttatatt cgatgaaaac atccatttac atccctatga attaccagaa tcatcacaat 3420 ggtgttatca gttaataaaa aacatgattt ctttacattg cagatataat aacaatttca 3480 agataaacta aaccttttgt tttgatttta aaaataaatc tttttgtaat gccaggttgc 3540 aatatataac gtttattgca tgtttttttt cacatgaaaa catgaaatat tcgacatttc 3600 atgatattaa ccttgatatg tgtgagataa agaattgcaa ttttaacaat tcagagatga 3660 atttcatttc gtgcgtcggg acaaatttta gcggttctac atttaacaat gtaaaaacaa 3720 caacagcgca actaattaag acaccaacaa agtggacgaa taatactcta aaatattggt 3780 tctccagttg taataaacgt aatatcatct tcacttttaa tacaatatct gatagaaata 3840 tgaaattaaa aggtatcaag gatatattac tgtcgttggt tgaccaaaaa gtcaatattt 3900 atagtgtaag gcaagagctt ctgaattttc ttaataatga tttatataaa aatgatggag 3960 agattctctc ttataaagaa tcaataatgt tgttttgtgc tgaatagccg aaattagatt 4020 attcagatta actaccgcac tctatgttgt gtttatatcc atgtaaggaa acaggtcatt 4080 tgtgaatcct gacaccagac tatgactatc gcccagggat aatccacaac cgctggaagc 4140 agtctctttt cagttggata aaaccgtaaa gtgcgattgc gataaataat aaatacaggc 4200 ttattattcc agtctttttt attgcgttgg ttgattcaaa tggctcggtt agtaaaatgc 4260 accattcact cggaaaactc aacatgttgc actcttatac gccgtatgga aaagacgtag 4320 gagtggtgta accatttaat cgtctcccaa cgtcaacgct tacacatcag cgacactggt 4380 ttaattaaag cataccagat ttctgatgag taagcgtctt ttcgtataac ctcattgtca 4440 taggaacgac ttgatccgtt tatttattcg ccatgttatt cagtatcaat tttcttaata 4500 gctttcacca tattttgatt ttcttttagc caagtcctga tattttgaac tacatcatta 4560 agtgtattct cttgttgata ctttatcttg aacctctctg tttcagagga aagatcccgg 4620 attgcattat ctatttcttc aattttttta tctattttct ttatatcatt ttcgattttg 4680 actttttcat cattatcatt taaattaagc atcttctcat taaaataaac ctttctttct 4740 agctgagcat ctcttgtgcc agaaaggttg gctaaatctt gaaatttata agtgaaattt 4800 tcattaatat aattattatt tctatcaatg ccccccaata aatattgttc aatgtcaaag 4860 aatgaagcaa tttcatgggc tacatttgct ggtttttcta tatatttctc ttggtttatt 4920 ttttcttctg ccttaaagtt tttcaccgtt aaaaaaagat tttgcttttc caaaaatttc 4980 tcctttgtag gcttattctt attctcataa tcgtagtaaa gtacttgcaa accagcaaaa 5040 tcaaagtaaa atctattacc atttggattg gcagtacgat atgttttttc atttccattt 5100 tcatcgtaat gtctatacca ataaaggtta ttatagattt tatgcatgaa attcacttta 5160 tcagtatcta tttcactagc tatatctttt tttctattgt acaaaacatt atctataata 5220 tattttatag tttcatcatt gagttgaaaa tcttttacat cataaccagg cataatgtta 5280 tgcagattaa ctaataagga ttgtaaatcg gctagtgcct ttttgtaatt attcttcata 5340 ttattgctat atttataaat atcttctatc cgtgaataaa tattcgttac cttttccatg 5400 aaaggtaaaa tgtctttttc agctatagct cctctatggt acatataaac aggaatttta 5460 acctgagtgt ttgcagcaag attaccactt aagatagtgg tatgagtatc aatagcacaa 5520 tcatacaagg gattcccacc ggttaactcg cccaaacaag cagcatataa acagcaatga 5580 ttaagattta aatgtttatc tatatcgtct tttatattat aatgagtttt aatattttgg 5640 aaaatatcat cgtggataaa atttaaaaga gctttatcca gattaagttt atttttattt 5700 tcactttctc cgaaatattt tcttggatca taatctcgta aatcttcacg aattccatct 5760 cgtttgcatg tcatattaac ataacgaaaa tcacaatcat aaaaattatt actatctcta 5820 aaaccaccgc gagtttttcc ataaaacgaa gtttctatga aatccattcc aacaccatta 5880 agctttgcta tattgcaaga taataaactg cttgcaataa cacttgcttc tttacacact 5940 ccatcttgaa gattacttgc atatacaaat gactgcataa acagatatgc accgactttc 6000 ttatcccctc tttggggatc ttgatttata gagtatattt ttgatgtctc tatcttgaaa 6060 tttttcattt cgcattgata caaaaaacac cctttaaaca taccgtaaat cggtatttta 6120 ttatttggtt ttacgttaca aagaacgtca tagctttcac aggtcacttt atcaaagcca 6180 acaagggaca cactctcgaa attacattcc tcaaaaaaac aattttcaaa tactgggcca 6240 ttaagatttt cgtaagatat attacctgtg aatgtcatct ttttaaagca acactgtttt 6300 agcgatacca gaacatcttt tttcagtgca gataaatcga ttatcatatt ttcaaagggg 6360 attttatttt ttaaatatac gcttagtttt tcattatcat tagggaactg cattttcaat 6420 atccctgatt gaaaagcctt ctcatcaaaa tgaatatcat gtttataact attataattg 6480 cgttcttctg ataatacaga acgcattgta ttttcttcag cattattatg attatctttc 6540 gagttaatat ttattttaaa tactctacta acaataatgt ctttattctc atctactgta 6600 aattctgtcg tcgtactaaa gcgccatttt tcttctggaa tagcgagaga tttaattctc 6660 tcaaatctct taactttgtc ctcagttttc gttacaaatt ctacaattgt ttctttagcc 6720 tccttaatat gatacatggg aaagagatcg agtataaatt cccaaagagt tagtttaaga 6780 aaagattgtc tatcaccagc tataaggttt gttatatctt tatgggttat tgaatacttc 6840 tcctcattac caacagacaa acaaaatttt tctgattttt ttgcaatcca ttattttcat 6900 ctggcatttt agtcagatta gcaaatttat ctgtaactgt actatatgat gatatagcca 6960 taatcatttc tcctgaacac aatatttatt cgcccgagca taatacattg ccgatttgtc 7020 ttaaaaagca tacctgggtg ttggtttgct acgattatga ctaaaccacc tatgaatact 7080 gtaaaaaatc gctcattttt tatgtctcga tatagggctt ttaccctgtt ttttgttttc 7140 ttttccattc tctgtgcagg tagcgatata aatgaaaaga ataacaaata tgtttttata 7200 gcgaggcact acattaaaag taaaataatt caaatgaaat aatgtatatt caatgtactg 7260 gggagagttt cgaggtgagt ttgtgtggca atatttcagt gagaaagtgt atcagcccgg 7320 taactatgta tgaccgggct gattgccaga tgcggcaaaa agctttatct ggcctacagt 7380 tagcactact ctttgggg 7398 <210> 1395 <211> 803 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(111..2519) <400> 1395 Met Val Ala Lys Leu Lys Pro Asp Val Phe Val Asn Thr Asn Pro Phe 1 5 10 15 Leu Glu Ala Met Tyr Lys Glu Arg Leu Ser His Lys Gly Tyr Ser Asp 20 25 30 Lys Ile Ala Leu Ser Ile Asn Asp Lys Lys Tyr Asn Val Asn Ser Lys 35 40 45 Asp Ile Glu Asn Ile Leu Asp Gly Lys Gly Asp Leu Phe Lys Lys Arg 50 55 60 Thr Leu Trp Glu Phe Val Arg Asp Leu Phe Pro Gly Ser His Ile Lys 65 70 75 80 Glu Val Lys Gly Leu Ile Tyr Glu Phe Val Thr Lys Val Asp Asn Lys 85 90 95 Ala Glu Val Phe Asp Lys Ile Lys Ser Leu Ala Lys Lys Glu Gln Gln 100 105 110 Trp Arg Phe Ser Thr Lys Thr Asp Phe Thr Thr Asn Glu Asn Asn Glu 115 120 125 Val Ile Val Ser Arg Ser Phe Asn Leu Tyr Thr Gly Ala Thr Ser Asn 130 135 140 Asp Asn Glu Lys Lys Gln Val Ser Ser Glu Arg Leu Thr Leu Asp Asn 145 150 155 160 Tyr Leu Asp Asp Leu His Phe Asp Asn Ser Pro Leu Val Arg Leu Thr 165 170 175 Phe Asp Asn Tyr Ser Val Lys Leu Ala Thr Leu Ile Lys Asn Lys Ile 180 185 190 Pro Ile Ile Asn Thr Thr Ile Asn Leu Ser Ser Leu Ser Lys Asp Val 195 200 205 Leu Asn Ser Leu Lys Tyr Cys Ser Phe Lys Asn Val Ile Phe Ser Gly 210 215 220 Val Ile Asn Ser Pro Asn Leu Glu Gly Pro Val Phe Glu Asn Cys Tyr 225 230 235 240 Phe Asp Asp Cys Lys Phe Asn Asn Ile Gln Leu Tyr Glu Thr Asn Asp 245 250 255 Asp Thr Val Glu Ser Gly Asn Lys Lys Pro Ile Lys Gly Met Phe Lys 260 265 270 Gly Cys Phe Ile Ser Lys Cys Lys Ile Glu Asn Tyr Arg Cys Glu Thr 275 280 285 Ser Lys Ile Tyr Thr Val Thr Gln Pro Asp Ser Ile Gln Glu Lys Leu 290 295 300 Gly Ser Tyr Leu Phe Met Gln Ser Phe Val Gln Asp Cys Ile Ile Gln 305 310 315 320 Gly Gly Cys Cys Pro Gly Ser Ser Ile Leu Leu Ser His Phe Tyr Asn 325 330 335 Cys Asn Ile Ile Gly Leu Asp Ala His Gly Met Asp Phe Leu Ala Asn 340 345 350 Ser Phe Asn Lys Ser Asn Tyr Asp Glu Ile Arg Gly Pro Asp Thr Gly 355 360 365 Thr Val Phe Tyr Asn Cys Asn Leu Lys His Ile Lys Ile Asn Asp Gly 370 375 380 Leu Arg Glu Asp Gly Ser Asp Arg Thr Met Phe Asn Pro Lys Glu Tyr 385 390 395 400 Phe Ser Asp Tyr Ile Glu Arg Arg Ser Arg Asn Leu Lys Leu Asp Asp 405 410 415 Asn Phe Ser Lys Cys Val Glu Ser Ile Lys Lys Gly Thr Asp Ser Ser 420 425 430 Phe Ser Lys Lys Asn Thr Glu Asn Asn Asn Val Phe Phe Lys Asn Ser 435 440 445 Asn Leu Ile Gly Ala Asn Leu Gly Tyr Tyr Tyr Ser Gly Asp Arg Cys 450 455 460 Lys Asp Cys Ala Ile Asp Pro Asn Thr Asn Tyr Ser Lys Asp Gly Leu 465 470 475 480 Thr Ala Gln Lys Tyr Met Tyr Met Asp Leu Asp Gly Ala Ile Ser Lys 485 490 495 Glu Gln Ile Pro Asp Phe Leu Lys Lys Val Ser Ala Ile Asn Ile Asp 500 505 510 Val Ile Asn Phe Tyr Asn Ser Glu Ser Lys Thr Lys Glu Lys Tyr Lys 515 520 525 Asn Ala Phe Leu Glu Leu Glu Ser Phe Leu Ser Thr Leu Tyr Val Glu 530 535 540 Asn Lys Ser Tyr Glu Glu Lys Tyr His Phe Asp Asn Ser Arg Val Glu 545 550 555 560 Phe Phe Ile Phe Lys Asp Met Gln Glu Asn Ala Gln Asn Ile Ile Asn 565 570 575 Asn Met Ile Glu Ser Asp Arg Ile Lys Phe Val Glu Ser Ile Ile Asn 580 585 590 Lys Met Ile Pro Pro Pro Asp Gly Thr Ile Leu Thr Glu Asn Pro Lys 595 600 605 Glu Tyr Val Gln Lys Gln Ile Lys Glu Ser His Lys Glu Ser Ala Thr 610 615 620 Asn Val Thr Phe Asp Tyr Lys Glu Leu Ala Pro Ile Phe Glu Gly Val 625 630 635 640 Glu Glu Lys Gln Ile Lys Ala Leu Ser Asn Gln Leu Glu His Ile Lys 645 650 655 Ser Phe Lys Thr Asp Tyr Asp Ser Arg Leu Asn Lys Tyr Ala Arg Asp 660 665 670 Phe Tyr Tyr Phe Ser Ser Ala Phe Ala Ile Asn Trp Glu Asp Leu Leu 675 680 685 Lys Asn Tyr Gln Glu Ile Arg Ala Ser Ile Lys Asp Tyr Asp Asp Leu 690 695 700 Leu Arg Glu Ile Lys Glu Leu Ile Ile Ser Arg Asn Lys Ser Leu Glu 705 710 715 720 Asp Lys Arg Thr Leu Phe Asp Asn Lys Arg Asp Asn Trp Asn Ser Ile 725 730 735 Glu Val Gln Asp Glu Val Asn Ala Leu Asn Ala Lys Ile Val Asp Cys 740 745 750 Asp Asp Lys Ile Arg Ser Lys Leu Thr Ile Val Arg Asn Asn Arg Leu 755 760 765 Glu Asn Gln Tyr Lys Asp Asp Lys Asn Ile Ser Asp Ala Met Arg Asn 770 775 780 Ile Leu Asp Trp Phe Glu Arg Tyr Pro Asp Ile Val Gln Asn Ile Thr 785 790 795 800 Gln Ala * <210> 1396 <211> 224 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2820..3491) <400> 1396 Met Asp Asn Leu Ile Gly Thr Pro Pro Asn His Ala Val Pro His Asn 1 5 10 15 Tyr Ile Asp Met Glu Gln Met Glu Tyr Leu Cys His Leu Asn Arg Phe 20 25 30 Ser Lys Leu Ser Asn Asp Phe Leu Ile Asn Gly Pro Arg Glu Asp Leu 35 40 45 Phe Thr Tyr Lys Tyr Val Leu Asp Gly Ser Phe Ser Asn Leu Gln His 50 55 60 Leu Leu Pro Lys Gly Gln Leu Gln Lys Ile Gln Gln Arg Leu Ser Ser 65 70 75 80 Leu Met His Lys Asn Met Phe His Cys Phe His Val Phe Leu Leu Lys 85 90 95 Leu Cys Ser Ile Glu Ser Ile Pro Leu Pro Asn Ala Asp Tyr Ala Phe 100 105 110 Phe Asp Asp Glu Met Pro Phe Thr Leu Thr Asp Glu Gln Ile Glu Asn 115 120 125 Ile Ser Phe Leu Asn Ala Tyr His Lys Glu Lys Lys Gly Asn Asn Asp 130 135 140 Ile Val Thr Phe Asp Phe Met Ser Ala Asp His His Tyr Asn Phe Ser 145 150 155 160 Thr Thr Ile Ala Leu Thr Asn Asp Ser Phe His Ile Ser Ser Ile Asn 165 170 175 Asn His Asn Ser Gln Val Ile Phe Asp Glu Asn Ile His Leu His Pro 180 185 190 Tyr Glu Leu Pro Glu Ser Ser Gln Trp Cys Tyr Gln Leu Ile Lys Asn 195 200 205 Met Ile Ser Leu His Cys Arg Tyr Asn Asn Asn Phe Lys Ile Asn * 210 215 220 <210> 1397 <211> 157 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3537..4007) <400> 1397 Leu Gln Tyr Ile Thr Phe Ile Ala Cys Phe Phe Ser His Glu Asn Met 1 5 10 15 Lys Tyr Ser Thr Phe His Asp Ile Asn Leu Asp Met Cys Glu Ile Lys 20 25 30 Asn Cys Asn Phe Asn Asn Ser Glu Met Asn Phe Ile Ser Cys Val Gly 35 40 45 Thr Asn Phe Ser Gly Ser Thr Phe Asn Asn Val Lys Thr Thr Thr Ala 50 55 60 Gln Leu Ile Lys Thr Pro Thr Lys Trp Thr Asn Asn Thr Leu Lys Tyr 65 70 75 80 Trp Phe Ser Ser Cys Asn Lys Arg Asn Ile Ile Phe Thr Phe Asn Thr 85 90 95 Ile Ser Asp Arg Asn Met Lys Leu Lys Gly Ile Lys Asp Ile Leu Leu 100 105 110 Ser Leu Val Asp Gln Lys Val Asn Ile Tyr Ser Val Arg Gln Glu Leu 115 120 125 Leu Asn Phe Leu Asn Asn Asp Leu Tyr Lys Asn Asp Gly Glu Ile Leu 130 135 140 Ser Tyr Lys Glu Ser Ile Met Leu Phe Cys Ala Glu * 145 150 155 <210> 1398 <211> 60 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4106..4285) <400> 1398 Met Leu Ser Phe Pro Ser Glu Trp Cys Ile Leu Leu Thr Glu Pro Phe 1 5 10 15 Glu Ser Thr Asn Ala Ile Lys Lys Thr Gly Ile Ile Ser Leu Tyr Leu 20 25 30 Leu Phe Ile Ala Ile Ala Leu Tyr Gly Phe Ile Gln Leu Lys Arg Asp 35 40 45 Cys Phe Gln Arg Leu Trp Ile Ile Pro Gly Arg * 50 55 <210> 1399 <211> 795 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4476..6860) <400> 1399 Leu Ser Val Gly Asn Glu Glu Lys Tyr Ser Ile Thr His Lys Asp Ile 1 5 10 15 Thr Asn Leu Ile Ala Gly Asp Arg Gln Ser Phe Leu Lys Leu Thr Leu 20 25 30 Trp Glu Phe Ile Leu Asp Leu Phe Pro Met Tyr His Ile Lys Glu Ala 35 40 45 Lys Glu Thr Ile Val Glu Phe Val Thr Lys Thr Glu Asp Lys Val Lys 50 55 60 Arg Phe Glu Arg Ile Lys Ser Leu Ala Ile Pro Glu Glu Lys Trp Arg 65 70 75 80 Phe Ser Thr Thr Thr Glu Phe Thr Val Asp Glu Asn Lys Asp Ile Ile 85 90 95 Val Ser Arg Val Phe Lys Ile Asn Ile Asn Ser Lys Asp Asn His Asn 100 105 110 Asn Ala Glu Glu Asn Thr Met Arg Ser Val Leu Ser Glu Glu Arg Asn 115 120 125 Tyr Asn Ser Tyr Lys His Asp Ile His Phe Asp Glu Lys Ala Phe Gln 130 135 140 Ser Gly Ile Leu Lys Met Gln Phe Pro Asn Asp Asn Glu Lys Leu Ser 145 150 155 160 Val Tyr Leu Lys Asn Lys Ile Pro Phe Glu Asn Met Ile Ile Asp Leu 165 170 175 Ser Ala Leu Lys Lys Asp Val Leu Val Ser Leu Lys Gln Cys Cys Phe 180 185 190 Lys Lys Met Thr Phe Thr Gly Asn Ile Ser Tyr Glu Asn Leu Asn Gly 195 200 205 Pro Val Phe Glu Asn Cys Phe Phe Glu Glu Cys Asn Phe Glu Ser Val 210 215 220 Ser Leu Val Gly Phe Asp Lys Val Thr Cys Glu Ser Tyr Asp Val Leu 225 230 235 240 Cys Asn Val Lys Pro Asn Asn Lys Ile Pro Ile Tyr Gly Met Phe Lys 245 250 255 Gly Cys Phe Leu Tyr Gln Cys Glu Met Lys Asn Phe Lys Ile Glu Thr 260 265 270 Ser Lys Ile Tyr Ser Ile Asn Gln Asp Pro Gln Arg Gly Asp Lys Lys 275 280 285 Val Gly Ala Tyr Leu Phe Met Gln Ser Phe Val Tyr Ala Ser Asn Leu 290 295 300 Gln Asp Gly Val Cys Lys Glu Ala Ser Val Ile Ala Ser Ser Leu Leu 305 310 315 320 Ser Cys Asn Ile Ala Lys Leu Asn Gly Val Gly Met Asp Phe Ile Glu 325 330 335 Thr Ser Phe Tyr Gly Lys Thr Arg Gly Gly Phe Arg Asp Ser Asn Asn 340 345 350 Phe Tyr Asp Cys Asp Phe Arg Tyr Val Asn Met Thr Cys Lys Arg Asp 355 360 365 Gly Ile Arg Glu Asp Leu Arg Asp Tyr Asp Pro Arg Lys Tyr Phe Gly 370 375 380 Glu Ser Glu Asn Lys Asn Lys Leu Asn Leu Asp Lys Ala Leu Leu Asn 385 390 395 400 Phe Ile His Asp Asp Ile Phe Gln Asn Ile Lys Thr His Tyr Asn Ile 405 410 415 Lys Asp Asp Ile Asp Lys His Leu Asn Leu Asn His Cys Cys Leu Tyr 420 425 430 Ala Ala Cys Leu Gly Glu Leu Thr Gly Gly Asn Pro Leu Tyr Asp Cys 435 440 445 Ala Ile Asp Thr His Thr Thr Ile Leu Ser Gly Asn Leu Ala Ala Asn 450 455 460 Thr Gln Val Lys Ile Pro Val Tyr Met Tyr His Arg Gly Ala Ile Ala 465 470 475 480 Glu Lys Asp Ile Leu Pro Phe Met Glu Lys Val Thr Asn Ile Tyr Ser 485 490 495 Arg Ile Glu Asp Ile Tyr Lys Tyr Ser Asn Asn Met Lys Asn Asn Tyr 500 505 510 Lys Lys Ala Leu Ala Asp Leu Gln Ser Leu Leu Val Asn Leu His Asn 515 520 525 Ile Met Pro Gly Tyr Asp Val Lys Asp Phe Gln Leu Asn Asp Glu Thr 530 535 540 Ile Lys Tyr Ile Ile Asp Asn Val Leu Tyr Asn Arg Lys Lys Asp Ile 545 550 555 560 Ala Ser Glu Ile Asp Thr Asp Lys Val Asn Phe Met His Lys Ile Tyr 565 570 575 Asn Asn Leu Tyr Trp Tyr Arg His Tyr Asp Glu Asn Gly Asn Glu Lys 580 585 590 Thr Tyr Arg Thr Ala Asn Pro Asn Gly Asn Arg Phe Tyr Phe Asp Phe 595 600 605 Ala Gly Leu Gln Val Leu Tyr Tyr Asp Tyr Glu Asn Lys Asn Lys Pro 610 615 620 Thr Lys Glu Lys Phe Leu Glu Lys Gln Asn Leu Phe Leu Thr Val Lys 625 630 635 640 Asn Phe Lys Ala Glu Glu Lys Ile Asn Gln Glu Lys Tyr Ile Glu Lys 645 650 655 Pro Ala Asn Val Ala His Glu Ile Ala Ser Phe Phe Asp Ile Glu Gln 660 665 670 Tyr Leu Leu Gly Gly Ile Asp Arg Asn Asn Asn Tyr Ile Asn Glu Asn 675 680 685 Phe Thr Tyr Lys Phe Gln Asp Leu Ala Asn Leu Ser Gly Thr Arg Asp 690 695 700 Ala Gln Leu Glu Arg Lys Val Tyr Phe Asn Glu Lys Met Leu Asn Leu 705 710 715 720 Asn Asp Asn Asp Glu Lys Val Lys Ile Glu Asn Asp Ile Lys Lys Ile 725 730 735 Asp Lys Lys Ile Glu Glu Ile Asp Asn Ala Ile Arg Asp Leu Ser Ser 740 745 750 Glu Thr Glu Arg Phe Lys Ile Lys Tyr Gln Gln Glu Asn Thr Leu Asn 755 760 765 Asp Val Val Gln Asn Ile Arg Thr Trp Leu Lys Glu Asn Gln Asn Met 770 775 780 Val Lys Ala Ile Lys Lys Ile Asp Thr Glu * 785 790 <210> 1400 <211> 47 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6827..6967) <400> 1400 Met Ile Met Ala Ile Ser Ser Tyr Ser Thr Val Thr Asp Lys Phe Ala 1 5 10 15 Asn Leu Thr Lys Met Pro Asp Glu Asn Asn Gly Leu Gln Lys Asn Gln 20 25 30 Lys Asn Phe Val Cys Leu Leu Val Met Arg Arg Ser Ile Gln * 35 40 45 <210> 1401 <211> 7304 <212> DNA <213> Escherichia coli O157:H7 <400> 1401 cattcctgaa aagaggccgg tgttgctacc ggcctcaggt cagattagcc attctttctt 60 cccgttttca gcccccgatg gaaatcgtta attcgcttaa tggttttaac cgcacgctgc 120 ggcaccgcgg aagccaccga ccagacaatc atttccaggc acaacaatac cgtaccatgt 180 agtggcgttt tccccttttc atccccgcgc ggaacatgaa tcacgatact ggcgtctttg 240 ctaaaacgtg aatccagcgc gtttgtcagc aaaataacag ggatccccag ccgtctcgct 300 tcacgcagcg ttgtcagccc ttcccggtgc gcagattttt gcgccatcat gatcagaaca 360 tcgccacgtt gaagcgcaat cagttgctcg gcaaggccaa tacccgtacg gtttagtgcc 420 gtggcaggca aacctatgcg gttgaatagt cgtgcggtat agtccgccag aatacccgaa 480 gcgccaatgc caaaaattgc gacttgccgt gcctgtacca acaacgctac cgcttgcgca 540 agcgcgtggc ggttttcagg ctctgacagg acattacagg tatacaaatg cccttcaaga 600 acaaagtcga ttgcggtgtt aacatcgctc gtcaagttac tcaccgtcgt agacatcttt 660 tcgctggaac taagggctgg accaagccac tgttccagag tgcgtttcag atcacgcagc 720 ccggcaaacc ccagggcctg tatagccctg ataactgtgg catcggaagt gttcaacgtg 780 gccgcaattt ccatcgccgt ttgatcgagt accacttcac gatgctcatt aatatagctg 840 gcgacagctc ttaacccagg cgttaactga ctcgcgcgag tgcgaaaacg ctcaccataa 900 atatcaaccc gcgttttgtc tttctgaatc atttggcctc cggtaaaggt cgccccgcaa 960 tttgtgattg tatctgcgca gccatcagcc ccagagatgc aaaggagtta gaaattgcct 1020 cttcacgaga aatcagcaca taacgcccgg aacgacaggc agtcagaaac tgacaccatc 1080 ccggcatgac tttttccatt gctgccagct catcctgagg tttaccaccg gtgtcaccgc 1140 gccaggttgc aaaaacaaaa tcggcatcca gttcaggtaa acgctccgcg ctcacatcca 1200 ttcgcccacc ttcaggaatg ctctcaatca gcggcggaaa gcgaaaacca gcatcgcgta 1260 atacccgccc cagcgaatga tagctatgca tcacattaat ttttccctga tttgcctgaa 1320 tcaccgatac cgttattttt tggctgtcca gcgtcgcctt cagcgcattg atttgtgcct 1380 gatagcggcg ttcaagtatc gccagctgcg actgcgttcc tgtcagttct gccagcttgc 1440 gatagatttc tggcgcgccc cctttgagat gatcaatgct caccgtgggc gcaatttttt 1500 ccagtcgttc aatgggtgta ttacgggtcg gttctgtgat gatcaggtca ggctttgccg 1560 ccacaatcgc ttcaatatca atatcagcgg tgccaataaa agcgatcgat gaattatcaa 1620 agtcgacacc tgtcaataac gcgcctgatc gaatgaaatg gctaccgtca ggccgagttc 1680 gcccgtggct ggcgacagga ggtacaccga gctcaatcag aggaatagtg atatcaagat 1740 cgtgtaaaga gacaattctc tttggatgag caggaacagt gactttgcgc cctaaatcat 1800 cagtaaagac ctgaacaggt tctgtcgcgc gggcaaagaa tgacaacagt atcagcagag 1860 aaaaaaataa acgcatataa ctcccattaa aaactgttcc tgcgctgcca gagcagtagc 1920 aaaaagaatg gtccaccaat caatgaaata atgattccgg caggcagttg caaaggcaaa 1980 aaagccaaac gaccaatgct atccgccagg atgactaaca acgcccccga tacggcgctc 2040 cccagcagta atgtcgtctg cccgccacgt agaataaaac gtgatatatg gggtgctatc 2100 aatccgacaa aaccgatgtt accaacacac gaaacgcaga cggctgtcag gattattggt 2160 gcggcgacac gtaacaacgc cagacgagaa ctattcaccc ctaacccggt tgcaacctga 2220 tgaccaagca gagcgatatc cgccgtcctg gcggtgaaca gcaataaaag agcggctggc 2280 aacatccaac aggctgaaat accgactaac atccagttag cagcatgcag gcttcccgat 2340 aaccacatca atgcagtttg tacatctcga acatctgcag tggtcataaa tacaccgata 2400 ccggcggcga aaaaccagga aacaccaata ccaatcagaa caaatcgcgg gcgggaaatt 2460 tcgcgtgcac aaaaaatcac gattaaagcc accaacaagc caccagcaag accagccact 2520 ggacgccaga acattcccag cattggaaac tggaaaatca gccacagcac cgccacgcta 2580 catccttctt tgacgccgat taaaccagga tcggcaaggc cgttacgcgc aatggattgc 2640 atcgcggccc ccgccatacc taacatggct ccgcatagca atgccatgat gactctcggc 2700 aagcgaatat cctgcacaat ataacgtgcg tctgtgctta cgttttctgg agcaaacaac 2760 gctcgtccta cttccgatgc cgggacaaaa aaagaaccat gcatcagacc gaatatcagt 2820 attccaaccg caaacagaaa cagcccacca agcaacacca gatttttagg gcgtaccagt 2880 gtcgaaaact taccaacacg tagtggacgt agcccgacgt tcattatccg actcatttga 2940 acattctcgt cgccataatg acaaaaacag gcgcaccaac taacgccgtc atgacaccgg 3000 tcgctaactc atggggcgtg aaaagcgtcc gagcaataat atctgccagt aataacaaaa 3060 gcgcgccgac acaagctgaa agagggagca gaacgcgcaa atccgctgat accagacgcc 3120 tgacaatctg cggtactagc agaccgacaa aaccaatggg gccagcaatc gatacggctg 3180 cgccacagag caacgcgatc gcaagcagag tgaatgttcg cgtgcggagt accgagacgc 3240 ccagcccctg cgccatgcga tcacccagtg ccaacatgtt aagagagggc gcaaggtaaa 3300 tggctaacac aacccccccc agagaaaacc aggcggacgt acccagcgtc gcccaatcct 3360 gccccgctaa atcacctgct agccatgtcc gcatcgccag cagtgtttgt tcgtcaagaa 3420 tcaggattgc agccgttatt gaggatacga acgccgatag cgccacgccg cataaagtaa 3480 ctttcattgg cgttagccct gaacgccctg cggaggaaag cagcaatatc aacaggaaca 3540 ataacgcgcc gcccgtagat gccagcagtg ggcgtccaac cggaaaggcc agcccaagcg 3600 cactggcagc aacgacagca agagcggctc cggcatttaa gcctaaaata tgtggctccc 3660 ccaatgggtt acgaatgaca gcctgcaaca aagcaccagc aactccaaga gaagcaccgg 3720 taagcaatgc tgccgctaaa cgcggcaaac ggagtcttac aattacgttg tgatcgaagt 3780 tttgcggttc aaaatgaaga aatgcctgca acaccgtttg tggtgcaata aatcgggcac 3840 caatccctgg atataccacg catcccacaa gcagtaaggc gaggaaaatt acagtaacca 3900 gccctgtgcg catcatactt tttctacacc acgaaacggc atgaagaacg gctttcccgt 3960 cagagtattt attgatgcgt gaacatcaac gtcaaagaca gcttttacca gctcaggcgt 4020 gcaatgctcc ccctcattca acacacgcac cactttcccc tggcgtaaaa atatcaacgt 4080 atcaccataa ttgacggcaa aattcagatc atgcaacacc acgacgactg tacgcccgtg 4140 atgacgcgtt aaatcatgta ataactcaag aatttcaacc tgataacgta aatcaagcca 4200 ggttgtgggt tcatccagta ggatataagg cgtcttttgc gccaacacca tcgcaatcca 4260 gcaacgctgg cgctgcccac cagagagttt ttcaacaggt aaatgagcaa actcctgcgt 4320 accggttaat ttcagggcct cttctaccgc ctgctcgtcg gcgtcgctcc attgacgtat 4380 gaaattttgc cagggaaaac gcccacgcga caccagttca taaacggtta agccctccgg 4440 caataatggc gactgcggca agatcccaag tctacgggat aacgctttcg ttggttgctc 4500 gtgaatcgct ttaccatcca gcaatattga gccgcccatg ggttgcaaga cacgtgcaat 4560 ggtgctgagc aacgtcgact ttccacagcc gtttgcccca accagaacgg tcattttttc 4620 tgtgggaacg gagaaagaaa caccatcaac aatgattttc ttgtgatacc cggcagaaac 4680 attgtcgagg atcagcccct gcccttttgc gttatgtgcc acgtgtacgc caacttaatc 4740 aaagaaaaac aaaaataaaa ctcattctct tttgagagtt tgacgccaca aaatgtagta 4800 gtcaagaagt taaaagccat acaaaaacaa ggtaaataac aggtgaaata tttttaaaga 4860 taaaaataaa atcattaaat attaataaat taccatcaat tgaattgcat taacctctca 4920 taaaaacaca tgtagcaatt ttttattatt tctcatttac tactacatta ccgcatgatt 4980 gaatgattct caattacata tccgatggta aaataacaaa cggatagtgc ttagtgagca 5040 acaagaaaca attttcactc acgacaatcc gtgagttttt gggataacag actaaatggc 5100 taagttcaca ccttcattct caggaatcaa aggtcgggcg ctcttttcac tgctctttgc 5160 agcaccaatg attcatgcaa ccgacactgc aacgaccaaa gatggcgaaa caatcactgt 5220 tacagcggat gcaaataccg caactgaggc gaccgatggt tatcaacctc tgagcacttc 5280 cacggcgaca ttaaccgata tgccgatgct ggatatcccg caggtggtca atacggttag 5340 cgatcaggtt ctggaaaatc agaatgcaac gacgctggat gaagcgcttt ataacgtcag 5400 taacgtggta cagaccaata cattaggcgg aactcaggac gcctttgtac gtcgtggttt 5460 tggtgctaac cgggatggct ccatcatgac caacggcctg cgaactgtac ttcctcgcag 5520 tttcaacgcc gccacagaac gtgtggaagt gctaaaaggt ccggcctcca cgctgtatgg 5580 cattctcgat cctggtggat tgattaacgt cgtgaccaag cgcccggaaa aaacattcca 5640 tggttctgtc tcagccacgt cctccagttt tggcggaggc actgggcaac ttgatatcac 5700 aggtcccatt gaaggcactc agctggcata ccgcctgacg ggggaagtgc aggatgaaga 5760 ttactggcga aacttcggta aagagcgcag tacatttatt gccccgtcac tcacctggtt 5820 tggtgataat gcaacagtaa ccatgctcta ttcccatcgg gactataaaa ctccgttcga 5880 tcgtggaacg attttcgacc ttacgacgaa acagcccgta aacgttgatc gaaaaatacg 5940 ttttgacgaa ccgtttaata ttacagatgg tcagtccgat ctggcgcaac tcaacgcaga 6000 atatcatctc aatagccagt ggacagcgcg ctttgattac agctacagcc aggataaata 6060 cagcgacaat caggctcgcg ttaccgcgta tgatgcaacg acaggaacgc tgacacggcg 6120 tgttgatgca actcagggat ctacccagcg tatgcattct actcgtgcgg atctgcaagg 6180 gaatgttgat attgctgggt tctataatga gattctgggt ggggtgtcat atgaatatta 6240 tgatcttctg cgcacagata tgattcgctg taaaaacgct aaagatttca atatctacaa 6300 ccccgtttat ggcaatacca gcaaatgcac aacggtttcg gcgtcggaca gtgatcagac 6360 gatcaaacag gagagctact cagcttatgc acaggatgcg ctctatctga ccgataactg 6420 gattgccgtc gccgggatcc gctatcagta ttacacgcag tatgcgggta aaggccgtcc 6480 ttttaatgtc aatactgaca gccgcgatga acaatggacg cccaaactgg ggttagtcta 6540 caaactgacg ccatcggtat ccttatttgc taattattcg caaacattta tgccgcaatc 6600 gtcaattgcc agctacatcg gagatcttcc accggaatca tctaatgctt acgaagtcgg 6660 ggcaaaattc gagctgttcg atggtataac cgcagatatt gcgctgtttg atatccataa 6720 acgtaacgtg ttgtataccg aaagtattgg tgatgaaacc atcgccaaaa cggcaggccg 6780 cgttcgttca agaggggtag aagtcgacct tgcgggagca ttaactgaaa acattaatat 6840 cattgccagc tacggctata ccgatgctaa ggttctggaa gatcctgatt atgcagggaa 6900 accattgccg aatgttcctc gtcataccgg ttcgctattc ctgacctatg acattcataa 6960 catgccaggc aataacacac tgacgtttgg cggtggtgga cattgcgtaa gccgtcgttc 7020 ggcaaccaat ggggctgact attatctgcc aggctatttc gttgccgatg ccttcgccgc 7080 atacaaaatg aaattgcagt atccggtcac actgcaatta aacgtcaaaa acctgtttga 7140 taaaacgtat tacacctctt ccatcgccac aaataatctg gggaatcaga ttggcgatcc 7200 gcgtgaagtg caattcacgg tgaaaatgga attttgatca aaaaagcccg gtatacactt 7260 gtataccggg ctatgtttta ttcttctggc gggaggatta tcag 7304 <210> 1402 <211> 296 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(45..932) <400> 1402 Met Ile Gln Lys Asp Lys Thr Arg Val Asp Ile Tyr Gly Glu Arg Phe 1 5 10 15 Arg Thr Arg Ala Ser Gln Leu Thr Pro Gly Leu Arg Ala Val Ala Ser 20 25 30 Tyr Ile Asn Glu His Arg Glu Val Val Leu Asp Gln Thr Ala Met Glu 35 40 45 Ile Ala Ala Thr Leu Asn Thr Ser Asp Ala Thr Val Ile Arg Ala Ile 50 55 60 Gln Ala Leu Gly Phe Ala Gly Leu Arg Asp Leu Lys Arg Thr Leu Glu 65 70 75 80 Gln Trp Leu Gly Pro Ala Leu Ser Ser Ser Glu Lys Met Ser Thr Thr 85 90 95 Val Ser Asn Leu Thr Ser Asp Val Asn Thr Ala Ile Asp Phe Val Leu 100 105 110 Glu Gly His Leu Tyr Thr Cys Asn Val Leu Ser Glu Pro Glu Asn Arg 115 120 125 His Ala Leu Ala Gln Ala Val Ala Leu Leu Val Gln Ala Arg Gln Val 130 135 140 Ala Ile Phe Gly Ile Gly Ala Ser Gly Ile Leu Ala Asp Tyr Thr Ala 145 150 155 160 Arg Leu Phe Asn Arg Ile Gly Leu Pro Ala Thr Ala Leu Asn Arg Thr 165 170 175 Gly Ile Gly Leu Ala Glu Gln Leu Ile Ala Leu Gln Arg Gly Asp Val 180 185 190 Leu Ile Met Met Ala Gln Lys Ser Ala His Arg Glu Gly Leu Thr Thr 195 200 205 Leu Arg Glu Ala Arg Arg Leu Gly Ile Pro Val Ile Leu Leu Thr Asn 210 215 220 Ala Leu Asp Ser Arg Phe Ser Lys Asp Ala Ser Ile Val Ile His Val 225 230 235 240 Pro Arg Gly Asp Glu Lys Gly Lys Thr Pro Leu His Gly Thr Val Leu 245 250 255 Leu Cys Leu Glu Met Ile Val Trp Ser Val Ala Ser Ala Val Pro Gln 260 265 270 Arg Ala Val Lys Thr Ile Lys Arg Ile Asn Asp Phe His Arg Gly Leu 275 280 285 Lys Thr Gly Arg Lys Asn Gly * 290 295 <210> 1403 <211> 316 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(929..1876) <400> 1403 Met Arg Leu Phe Phe Ser Leu Leu Ile Leu Leu Ser Phe Phe Ala Arg 1 5 10 15 Ala Thr Glu Pro Val Gln Val Phe Thr Asp Asp Leu Gly Arg Lys Val 20 25 30 Thr Val Pro Ala His Pro Lys Arg Ile Val Ser Leu His Asp Leu Asp 35 40 45 Ile Thr Ile Pro Leu Ile Glu Leu Gly Val Pro Pro Val Ala Ser His 50 55 60 Gly Arg Thr Arg Pro Asp Gly Ser His Phe Ile Arg Ser Gly Ala Leu 65 70 75 80 Leu Thr Gly Val Asp Phe Asp Asn Ser Ser Ile Ala Phe Ile Gly Thr 85 90 95 Ala Asp Ile Asp Ile Glu Ala Ile Val Ala Ala Lys Pro Asp Leu Ile 100 105 110 Ile Thr Glu Pro Thr Arg Asn Thr Pro Ile Glu Arg Leu Glu Lys Ile 115 120 125 Ala Pro Thr Val Ser Ile Asp His Leu Lys Gly Gly Ala Pro Glu Ile 130 135 140 Tyr Arg Lys Leu Ala Glu Leu Thr Gly Thr Gln Ser Gln Leu Ala Ile 145 150 155 160 Leu Glu Arg Arg Tyr Gln Ala Gln Ile Asn Ala Leu Lys Ala Thr Leu 165 170 175 Asp Ser Gln Lys Ile Thr Val Ser Val Ile Gln Ala Asn Gln Gly Lys 180 185 190 Ile Asn Val Met His Ser Tyr His Ser Leu Gly Arg Val Leu Arg Asp 195 200 205 Ala Gly Phe Arg Phe Pro Pro Leu Ile Glu Ser Ile Pro Glu Gly Gly 210 215 220 Arg Met Asp Val Ser Ala Glu Arg Leu Pro Glu Leu Asp Ala Asp Phe 225 230 235 240 Val Phe Ala Thr Trp Arg Gly Asp Thr Gly Gly Lys Pro Gln Asp Glu 245 250 255 Leu Ala Ala Met Glu Lys Val Met Pro Gly Trp Cys Gln Phe Leu Thr 260 265 270 Ala Cys Arg Ser Gly Arg Tyr Val Leu Ile Ser Arg Glu Glu Ala Ile 275 280 285 Ser Asn Ser Phe Ala Ser Leu Gly Leu Met Ala Ala Gln Ile Gln Ser 290 295 300 Gln Ile Ala Gly Arg Pro Leu Pro Glu Ala Lys * 305 310 315 <210> 1404 <211> 350 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1887..2936) <400> 1404 Met Ser Arg Ile Met Asn Val Gly Leu Arg Pro Leu Arg Val Gly Lys 1 5 10 15 Phe Ser Thr Leu Val Arg Pro Lys Asn Leu Val Leu Leu Gly Gly Leu 20 25 30 Phe Leu Phe Ala Val Gly Ile Leu Ile Phe Gly Leu Met His Gly Ser 35 40 45 Phe Phe Val Pro Ala Ser Glu Val Gly Arg Ala Leu Phe Ala Pro Glu 50 55 60 Asn Val Ser Thr Asp Ala Arg Tyr Ile Val Gln Asp Ile Arg Leu Pro 65 70 75 80 Arg Val Ile Met Ala Leu Leu Cys Gly Ala Met Leu Gly Met Ala Gly 85 90 95 Ala Ala Met Gln Ser Ile Ala Arg Asn Gly Leu Ala Asp Pro Gly Leu 100 105 110 Ile Gly Val Lys Glu Gly Cys Ser Val Ala Val Leu Trp Leu Ile Phe 115 120 125 Gln Phe Pro Met Leu Gly Met Phe Trp Arg Pro Val Ala Gly Leu Ala 130 135 140 Gly Gly Leu Leu Val Ala Leu Ile Val Ile Phe Cys Ala Arg Glu Ile 145 150 155 160 Ser Arg Pro Arg Phe Val Leu Ile Gly Ile Gly Val Ser Trp Phe Phe 165 170 175 Ala Ala Gly Ile Gly Val Phe Met Thr Thr Ala Asp Val Arg Asp Val 180 185 190 Gln Thr Ala Leu Met Trp Leu Ser Gly Ser Leu His Ala Ala Asn Trp 195 200 205 Met Leu Val Gly Ile Ser Ala Cys Trp Met Leu Pro Ala Ala Leu Leu 210 215 220 Leu Leu Phe Thr Ala Arg Thr Ala Asp Ile Ala Leu Leu Gly His Gln 225 230 235 240 Val Ala Thr Gly Leu Gly Val Asn Ser Ser Arg Leu Ala Leu Leu Arg 245 250 255 Val Ala Ala Pro Ile Ile Leu Thr Ala Val Cys Val Ser Cys Val Gly 260 265 270 Asn Ile Gly Phe Val Gly Leu Ile Ala Pro His Ile Ser Arg Phe Ile 275 280 285 Leu Arg Gly Gly Gln Thr Thr Leu Leu Leu Gly Ser Ala Val Ser Gly 290 295 300 Ala Leu Leu Val Ile Leu Ala Asp Ser Ile Gly Arg Leu Ala Phe Leu 305 310 315 320 Pro Leu Gln Leu Pro Ala Gly Ile Ile Ile Ser Leu Ile Gly Gly Pro 325 330 335 Phe Phe Leu Leu Leu Leu Trp Gln Arg Arg Asn Ser Phe * 340 345 <210> 1405 <211> 328 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2933..3916) <400> 1405 Met Met Arg Thr Gly Leu Val Thr Val Ile Phe Leu Ala Leu Leu Leu 1 5 10 15 Val Gly Cys Val Val Tyr Pro Gly Ile Gly Ala Arg Phe Ile Ala Pro 20 25 30 Gln Thr Val Leu Gln Ala Phe Leu His Phe Glu Pro Gln Asn Phe Asp 35 40 45 His Asn Val Ile Val Arg Leu Arg Leu Pro Arg Leu Ala Ala Ala Leu 50 55 60 Leu Thr Gly Ala Ser Leu Gly Val Ala Gly Ala Leu Leu Gln Ala Val 65 70 75 80 Ile Arg Asn Pro Leu Gly Glu Pro His Ile Leu Gly Leu Asn Ala Gly 85 90 95 Ala Ala Leu Ala Val Val Ala Ala Ser Ala Leu Gly Leu Ala Phe Pro 100 105 110 Val Gly Arg Pro Leu Leu Ala Ser Thr Gly Gly Ala Leu Leu Phe Leu 115 120 125 Leu Ile Leu Leu Leu Ser Ser Ala Gly Arg Ser Gly Leu Thr Pro Met 130 135 140 Lys Val Thr Leu Cys Gly Val Ala Leu Ser Ala Phe Val Ser Ser Ile 145 150 155 160 Thr Ala Ala Ile Leu Ile Leu Asp Glu Gln Thr Leu Leu Ala Met Arg 165 170 175 Thr Trp Leu Ala Gly Asp Leu Ala Gly Gln Asp Trp Ala Thr Leu Gly 180 185 190 Thr Ser Ala Trp Phe Ser Leu Gly Gly Val Val Leu Ala Ile Tyr Leu 195 200 205 Ala Pro Ser Leu Asn Met Leu Ala Leu Gly Asp Arg Met Ala Gln Gly 210 215 220 Leu Gly Val Ser Val Leu Arg Thr Arg Thr Phe Thr Leu Leu Ala Ile 225 230 235 240 Ala Leu Leu Cys Gly Ala Ala Val Ser Ile Ala Gly Pro Ile Gly Phe 245 250 255 Val Gly Leu Leu Val Pro Gln Ile Val Arg Arg Leu Val Ser Ala Asp 260 265 270 Leu Arg Val Leu Leu Pro Leu Ser Ala Cys Val Gly Ala Leu Leu Leu 275 280 285 Leu Leu Ala Asp Ile Ile Ala Arg Thr Leu Phe Thr Pro His Glu Leu 290 295 300 Ala Thr Gly Val Met Thr Ala Leu Val Gly Ala Pro Val Phe Val Ile 305 310 315 320 Met Ala Thr Arg Met Phe Lys * 325 <210> 1406 <211> 270 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3913..4722) <400> 1406 Val Ala His Asn Ala Lys Gly Gln Gly Leu Ile Leu Asp Asn Val Ser 1 5 10 15 Ala Gly Tyr His Lys Lys Ile Ile Val Asp Gly Val Ser Phe Ser Val 20 25 30 Pro Thr Glu Lys Met Thr Val Leu Val Gly Ala Asn Gly Cys Gly Lys 35 40 45 Ser Thr Leu Leu Ser Thr Ile Ala Arg Val Leu Gln Pro Met Gly Gly 50 55 60 Ser Ile Leu Leu Asp Gly Lys Ala Ile His Glu Gln Pro Thr Lys Ala 65 70 75 80 Leu Ser Arg Arg Leu Gly Ile Leu Pro Gln Ser Pro Leu Leu Pro Glu 85 90 95 Gly Leu Thr Val Tyr Glu Leu Val Ser Arg Gly Arg Phe Pro Trp Gln 100 105 110 Asn Phe Ile Arg Gln Trp Ser Asp Ala Asp Glu Gln Ala Val Glu Glu 115 120 125 Ala Leu Lys Leu Thr Gly Thr Gln Glu Phe Ala His Leu Pro Val Glu 130 135 140 Lys Leu Ser Gly Gly Gln Arg Gln Arg Cys Trp Ile Ala Met Val Leu 145 150 155 160 Ala Gln Lys Thr Pro Tyr Ile Leu Leu Asp Glu Pro Thr Thr Trp Leu 165 170 175 Asp Leu Arg Tyr Gln Val Glu Ile Leu Glu Leu Leu His Asp Leu Thr 180 185 190 Arg His His Gly Arg Thr Val Val Val Val Leu His Asp Leu Asn Phe 195 200 205 Ala Val Asn Tyr Gly Asp Thr Leu Ile Phe Leu Arg Gln Gly Lys Val 210 215 220 Val Arg Val Leu Asn Glu Gly Glu His Cys Thr Pro Glu Leu Val Lys 225 230 235 240 Ala Val Phe Asp Val Asp Val His Ala Ser Ile Asn Thr Leu Thr Gly 245 250 255 Lys Pro Phe Phe Met Pro Phe Arg Gly Val Glu Lys Val * 260 265 <210> 1407 <211> 714 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5096..7237) <400> 1407 Met Ala Lys Phe Thr Pro Ser Phe Ser Gly Ile Lys Gly Arg Ala Leu 1 5 10 15 Phe Ser Leu Leu Phe Ala Ala Pro Met Ile His Ala Thr Asp Thr Ala 20 25 30 Thr Thr Lys Asp Gly Glu Thr Ile Thr Val Thr Ala Asp Ala Asn Thr 35 40 45 Ala Thr Glu Ala Thr Asp Gly Tyr Gln Pro Leu Ser Thr Ser Thr Ala 50 55 60 Thr Leu Thr Asp Met Pro Met Leu Asp Ile Pro Gln Val Val Asn Thr 65 70 75 80 Val Ser Asp Gln Val Leu Glu Asn Gln Asn Ala Thr Thr Leu Asp Glu 85 90 95 Ala Leu Tyr Asn Val Ser Asn Val Val Gln Thr Asn Thr Leu Gly Gly 100 105 110 Thr Gln Asp Ala Phe Val Arg Arg Gly Phe Gly Ala Asn Arg Asp Gly 115 120 125 Ser Ile Met Thr Asn Gly Leu Arg Thr Val Leu Pro Arg Ser Phe Asn 130 135 140 Ala Ala Thr Glu Arg Val Glu Val Leu Lys Gly Pro Ala Ser Thr Leu 145 150 155 160 Tyr Gly Ile Leu Asp Pro Gly Gly Leu Ile Asn Val Val Thr Lys Arg 165 170 175 Pro Glu Lys Thr Phe His Gly Ser Val Ser Ala Thr Ser Ser Ser Phe 180 185 190 Gly Gly Gly Thr Gly Gln Leu Asp Ile Thr Gly Pro Ile Glu Gly Thr 195 200 205 Gln Leu Ala Tyr Arg Leu Thr Gly Glu Val Gln Asp Glu Asp Tyr Trp 210 215 220 Arg Asn Phe Gly Lys Glu Arg Ser Thr Phe Ile Ala Pro Ser Leu Thr 225 230 235 240 Trp Phe Gly Asp Asn Ala Thr Val Thr Met Leu Tyr Ser His Arg Asp 245 250 255 Tyr Lys Thr Pro Phe Asp Arg Gly Thr Ile Phe Asp Leu Thr Thr Lys 260 265 270 Gln Pro Val Asn Val Asp Arg Lys Ile Arg Phe Asp Glu Pro Phe Asn 275 280 285 Ile Thr Asp Gly Gln Ser Asp Leu Ala Gln Leu Asn Ala Glu Tyr His 290 295 300 Leu Asn Ser Gln Trp Thr Ala Arg Phe Asp Tyr Ser Tyr Ser Gln Asp 305 310 315 320 Lys Tyr Ser Asp Asn Gln Ala Arg Val Thr Ala Tyr Asp Ala Thr Thr 325 330 335 Gly Thr Leu Thr Arg Arg Val Asp Ala Thr Gln Gly Ser Thr Gln Arg 340 345 350 Met His Ser Thr Arg Ala Asp Leu Gln Gly Asn Val Asp Ile Ala Gly 355 360 365 Phe Tyr Asn Glu Ile Leu Gly Gly Val Ser Tyr Glu Tyr Tyr Asp Leu 370 375 380 Leu Arg Thr Asp Met Ile Arg Cys Lys Asn Ala Lys Asp Phe Asn Ile 385 390 395 400 Tyr Asn Pro Val Tyr Gly Asn Thr Ser Lys Cys Thr Thr Val Ser Ala 405 410 415 Ser Asp Ser Asp Gln Thr Ile Lys Gln Glu Ser Tyr Ser Ala Tyr Ala 420 425 430 Gln Asp Ala Leu Tyr Leu Thr Asp Asn Trp Ile Ala Val Ala Gly Ile 435 440 445 Arg Tyr Gln Tyr Tyr Thr Gln Tyr Ala Gly Lys Gly Arg Pro Phe Asn 450 455 460 Val Asn Thr Asp Ser Arg Asp Glu Gln Trp Thr Pro Lys Leu Gly Leu 465 470 475 480 Val Tyr Lys Leu Thr Pro Ser Val Ser Leu Phe Ala Asn Tyr Ser Gln 485 490 495 Thr Phe Met Pro Gln Ser Ser Ile Ala Ser Tyr Ile Gly Asp Leu Pro 500 505 510 Pro Glu Ser Ser Asn Ala Tyr Glu Val Gly Ala Lys Phe Glu Leu Phe 515 520 525 Asp Gly Ile Thr Ala Asp Ile Ala Leu Phe Asp Ile His Lys Arg Asn 530 535 540 Val Leu Tyr Thr Glu Ser Ile Gly Asp Glu Thr Ile Ala Lys Thr Ala 545 550 555 560 Gly Arg Val Arg Ser Arg Gly Val Glu Val Asp Leu Ala Gly Ala Leu 565 570 575 Thr Glu Asn Ile Asn Ile Ile Ala Ser Tyr Gly Tyr Thr Asp Ala Lys 580 585 590 Val Leu Glu Asp Pro Asp Tyr Ala Gly Lys Pro Leu Pro Asn Val Pro 595 600 605 Arg His Thr Gly Ser Leu Phe Leu Thr Tyr Asp Ile His Asn Met Pro 610 615 620 Gly Asn Asn Thr Leu Thr Phe Gly Gly Gly Gly His Cys Val Ser Arg 625 630 635 640 Arg Ser Ala Thr Asn Gly Ala Asp Tyr Tyr Leu Pro Gly Tyr Phe Val 645 650 655 Ala Asp Ala Phe Ala Ala Tyr Lys Met Lys Leu Gln Tyr Pro Val Thr 660 665 670 Leu Gln Leu Asn Val Lys Asn Leu Phe Asp Lys Thr Tyr Tyr Thr Ser 675 680 685 Ser Ile Ala Thr Asn Asn Leu Gly Asn Gln Ile Gly Asp Pro Arg Glu 690 695 700 Val Gln Phe Thr Val Lys Met Glu Phe * 705 710 <210> 1408 <211> 7215 <212> DNA <213> Escherichia coli O157:H7 <400> 1408 tttcatccgc ccgacatgtt gtacatgcaa tatgtgcgga ttattattca ttttcacgga 60 ggttgctatg tcaaccggat tacgtttcac gctggaagtg gacggcctgc caccggacgc 120 gtttgcggtg gtctcctttc atctgaacca gtcactctct tcactttttt ccctcgacct 180 ttctctggtc agtcagcagt ttctttccct tgaatttgcg caggtgctgg acaaaatggc 240 ctacctgacg gtatggcagg gcgatgacgt acagcgccgg gtgaaaggtg tggtgacctg 300 gtttgaactg ggggagaacg acaaaaacca gatgctgtac agcatgaagg tgtgcccacc 360 gctgtggcgc acagggctgc gccagaactt ccgtatcttc cagaatgagg acatcgaaag 420 catactcgct acgatcctga aagaaaacgg tgtgaccgag tggagtccgc tgttcagcga 480 gccgcatcct tcccgtgagt tttgtgtcca gtacggcgaa actgattacg atttcctgtg 540 ccggatggcg gcggaggaag gcatcttctt ttatgaggag cacgcgcaaa aaagtatcga 600 ccagagcctg gtcctgtgcg acaccgtgcg ttatctgccg gagtcctttg agatcccctg 660 gaacccgaac acccgtaccg aggtgagcac cctatgcatc agccagttcc gctacagcgc 720 acaaatccgc ccttcttccg tggtgaccaa ggactacacc tttaaacgac ccggctgggc 780 agggcgtttt gatcaggaag gccagtacca ggattaccag cgcacacagt atgaagtgta 840 tgactacccc ggacgtttca agggtgccca cgggcagaac tttgcccgct ggcagatgga 900 tggctggcgc aacaacgcag aagtggcgcg cggaacaagc cgttctccgg aaatatggcc 960 gggacggcga attgtgctga cggggcatcc gcaggcgaac ctgaaccggg aatggcaggt 1020 ggtggcaagt gaactgcacg gcgagcagcc acaggcggtg ccgggacgca ggggttcagg 1080 taccacgctg aataaccact ttgcggtaat accggcagac cggacatggc gaccacagcc 1140 gttgctgaaa ccgctggtgg atggcccgca gagcgccgtc gtgacgggac cggcaggcga 1200 ggaaatcttc tgcgacgaac atggtcgcgt gcgggtgaaa tttaactggg accgctataa 1260 cccgtcaaac caggacagtt catgctggat ccgtgtggca caggcgtggg caggcaccgg 1320 ctttggcaac ctggcgatac cgcgtgtggg tcaggaggtg attgtggact tcctcaacgg 1380 cgatccggac cagccgatta ttatggggcg tacctaccac caggaaaacc gcacacccgg 1440 cagcctgccg gggacgaaga cgcagatgac cattcgttcg aaaaactata agggcagcgg 1500 gtttaatgaa ctgaagtttg acgatgcgac agggaaagaa caggtctaca tccacgcgca 1560 gaagaacatg aacaccgagg tgctgaataa ccgcaccacg gatgtgataa acaaccatgc 1620 tgagaccatt ggcaacaatc agatgattgc ggttaccaac aatcagatac agacggtggg 1680 cgttaaccag atagagacgg tgggcagtaa ccagatcatt aacgtgggtt ctgttcaggt 1740 ggaaacgatt ggacttgttc gtgcgctgac cgtgggcgtg gcgtaccaga cgacggtagg 1800 tggcattatg aacacttcgg tggctctgat gcagtcctcg cagatcggtt tgcataaatc 1860 gttgagggtc gggctgggtt atgacgtcaa agtcggaaat aacgttacct tcaccgttgg 1920 taaaacgaaa aaggatgata ccgggcagac cgcgatttac tccgccggtg agcatctgga 1980 gctctgctgt ggtaaggcaa ggctggtgct gacgaaggac ggacaaattt ttctcaacgg 2040 cacaaaaatt catttgcagg gtaaggagca ggttaatggt gactcactgt tgattaactg 2100 gaactgtgca gcctcgaaat ccccaccgaa gacccctgat gaaaagcagg atacgccgga 2160 tatgagagag tactgatccc gtacctgttc ggtattcagt aacaaacaag cattaaaaat 2220 aaacagaaga aggaattgaa tcatgagcgg aaaaccagcg gcgcgtcagg gagatatgac 2280 tcagtatggc ggtcccattg tccagggttc ggcaggtgta agaattggcg cgccaactgg 2340 cgtggcgtgc tcggtgtgcc cgggcgggat gacttcgggc aacccggtaa atccgctgct 2400 gggggcgaag gtgctgcccg gcgagacgga ccttgcgctg cccggcccgc tgccgttcat 2460 tctctcccgc acctacagca gctaccggac ccggacgcct gcgccggtgg ggatttttgg 2520 ccccggctgg aaagcgcctt ctgatatccg cttacagcta cgcgatgatg cactggtact 2580 caatgacaac ggcgggcgga gcattcactt tgagccgctg ctgccggggg aggcggtgta 2640 cagccgcagc gagtcaatgt ggctggtgcg cggtggtaag gcagcgcagc cggacggcca 2700 cacgctggcg cggctgtggg gggcgctgcc gccggatatc cggttaagcc cgcatcttta 2760 cctggcgacc aacagcgcac aggggccgtg gtggatactg gggtggtcag agcgggtgcc 2820 gggtgctgag gacgtactgc cagcgccgct gccgccgtac cgggtgctta ccgggatggc 2880 ggaccgcttc gggcggacgc tgacgtacag gcgtgaggcc gccggtgacc tggccgggga 2940 aatcaccggc gtgacggacg gtgccgggcg ggagttccgt ctggtgctga ccacgcaggc 3000 gcagcgggcg gaagaggccc gtaaacagca caccgcttct ttatcttccc ctgacacccc 3060 ccgccctctt tcagactcag cgttccccga cacactgccc ggtaccgaat acggtcccga 3120 cagaggtatc cgcctttcgg cggtgtggct gacgcacgac ccggcatacc cggaaagcct 3180 gcccggtgcg ccactggcgc ggtacacgta tacggaagcc ggtgaactgc tggcggtata 3240 tgaccgcagc aatacgcagg tgcgcgcttt cacgtatgac gcgcagcatc cgggccggat 3300 ggtggcgcac cgttacgcgg gaaggccgga gatgcgctac cgctacgacg ataccgggcg 3360 ggtggtggag cagctgaacc cggcaggcct gagttaccgc taccagtatg agcaggaccg 3420 catcaccgtc acggacagcc tgaaccggcg tgaggtgctg catacagaag gcggggccgg 3480 gctgaagcgg gtggtgaaaa aagaactggc ggacggcagc gtcacgcaca gcgggtatga 3540 cgcggcagga aggctcacgg cgcagacgga cgcggcggga cggcggacag agtacggtct 3600 gaatgtggtg tccggcgata tcacggacat caccacaccg gacgggcggg agacgaaatt 3660 ttactataac gacgggaacc agctgacggc ggtggtgtcc ccggacgggc tggagagccg 3720 ccgggcatat gatgaaccgg gcaggctggt atcggagaca tcgcgctgtg gggacgtcat 3780 ccggtatgct tatgataatc cgcacagtga attaccggcc acgacaacag atgcgacggg 3840 cagcacccgg cagatgacct ggagccgcta cgggcagttg ctggcgttca ccgactgctc 3900 gggctaccag acccgttatg aatacgaccg ctttggtcag atgacggcgg tccaccgtga 3960 ggaaggtatc agccgttacc gccgctatga caaccgtggc cggttaacct cggtgaaaga 4020 cgcacagggc catgaaacgc ggtatgagta caacgccgca ggcgacctga ctgccgttat 4080 cactccggac ggcaaccgga gcgagacaca gtacgatgcg tggggaaaag cggtcagcac 4140 cacgcagggc gggctgacgc gcagtatgga gtatgacctc gccggacgca tcaccacgct 4200 gaccaacgag aacggcagcc ggagtgagtt tacctacgat gcgcttgacc ggctggtaca 4260 gcagcgcggc tttgacgggc ggacgcaacg ttaccactat gacctgaccg gaaaactcac 4320 gcagagtgaa gatgaggggc ttgtcaccct ctggcactac gacgaatcgg accgcctcac 4380 tcaccgcacg gtgaacggcg aaccggcaga gcagtggcag tacgacgagc acggctggct 4440 gacagaaatc agccacctga gcgaaggcca tcaggtggcg gtgcattacg gttatgatga 4500 taagggccgc ctggccgggg agcgccagac ggtgcataac ccggagacgg gggaactgct 4560 gtggcagcat gagacagagc acgcatacaa cgaacagggt ctggcaaacc gcgtcacgcc 4620 ggacagcctg ccgcgggtgg agtggctgac ctacggcagc ggttatcttg cggggatgaa 4680 gctgggcggg acgccgctgg tggagttcac gcgcgacagg ctgcaccgcg agacggtgcg 4740 cagcttcggc aataacgcat acgaactgac cagcacatac actcccgcag gccatttaca 4800 gagccagcgc ctgaacagcc aggtgtatga ccgtgactac gactggaatg acaatggcga 4860 cctggtgcgc atcagcggcc cgcgacagac gtgggaatat ggctacagtg ccacgggcag 4920 gctggagagc gtgcgcaccc ttgcatcaga cctggatatc cgcatcccgt atgcgaccga 4980 cccggcggga aaccggctgc cggacccgga gctacacccg gacagcacgc tcacggcgtg 5040 gccggataac cgcatcgcgg aggatgcgca ctatgtctac cgacacgatg aatacggcag 5100 gctgacggag aagacggacc gcatcccggc gggtgtgata cggacggacg acgagcggac 5160 ccaccactac cactacgaca gccagcaccg cctggtgttc tacacgcgga tacagcatgg 5220 cgagccactg gtcgagagcc gctacctcta cgacccgctg ggacggcgaa tggcaaaacg 5280 ggtctggcgg cgggagcgtg acctgacggg gtggatgtcg ctgtcgcgta aaccggaggt 5340 gacgtggtat ggctgggacg gagacaggct gacgacggtg cagactgaca ccacacgtat 5400 ccagacggta tacgagccgg gaagcttcac gccgctcatc cgggtcgaga cagagaacgg 5460 cgagcgggaa aaagcgcagc ggcgcagcct ggcagagacg ctccagcagg aagggagtga 5520 gaacggccac ggcgtggtgt tcccggctga actggtgcgg ctgctggaca ggctggagga 5580 agaaatccgg gcagaccgcg tgagcagtga aagccgggcg tggcttgcgc agtgcgggct 5640 gacggtggag caactggcca gacaggtgga gccggaatac acaccggcgc gaaaagttca 5700 tttttaccac tgcgaccacc ggggcctgcc gctggcgctc atcagcgaag acggcaatac 5760 ggcgtggcgc ggggagtatg atgaatgggg caaccagctt aatgaagaga acccgtatta 5820 cctgcaccag ccataccgtc tgccggggca gcagcatgat gaggaatcag ggctgtacta 5880 taaccggaac cggtactatg acccgctaca ggggaggtat attacacaag accccattgg 5940 gctggcgggg ggatggaatc tgtataatta cccactgaat ccgataataa ggatggatcc 6000 tttgggtttg tataatttat atcaattatt atatgatgtt tggcatgatg attcatatgg 6060 aacatcatca attgatatta ctggcagtgg agatctaata tcattaggtg gtcatgcagg 6120 acttggcgtt gcgtttgcta aaaagaaagg tgaaatgtta tctgatattt gtatttatgc 6180 tacagcatgc ggacatgcag gaattggtgg tgggataaat gcggctatca catattctta 6240 ctccaagtct ttacctacat cgggagtcag caattcagta ggtgtaacgg ttggcggcgg 6300 agttgggggg cattttgcgt atacttatgt agtggatgtt gataatccag aatcatcgac 6360 agaatctgtt ggtatcggtg caggtgttga cgcttcagtt atgactctgg cttgtagaac 6420 gtggcaagaa tgctgggtca attaacagga ggaaatatga aaaaatatat atttttagtt 6480 ttatttttat tgtatggttg ttctccagtg gacatagagc cagctagaca agaagttaat 6540 atctttcgtg gtttatatca gacagggaaa tacagtgata tatataaaat cacttcaagt 6600 gattttcaga ctgccacatc tgaaaaaaat ttatcgacat aatgaacgaa gcaaaagaaa 6660 aagatcttgg gacttataaa aaatcaaccc ttaaaactga aaaaatcact cgcggattat 6720 tttcaaacga tgaaattaca ttgatatatt tctcagaata ttcaaaaaga attgtccaag 6780 aggtttttgt gtttaatgtt gaagacaaaa aagtaaaatt aaaaggttat aggtatgatt 6840 cgattaatta aattttttga tgatgacttc aattagtaga acatgtattt ttcgataaaa 6900 gcaccgatga ctttttcatg aagttctaca gagcgcgaga aacagatggt tctgcgagtc 6960 agacgtttga ttcaggttct caggggcaga ttcagggaaa gatcacaggg aaagatcatc 7020 ggtgtgccgt aggcacaaag atgcaaaacg ggacgttttg catgtaataa gcataagctt 7080 gtgaagagat ggtggcaggc ccaccgggat ctgctgtcga aagtcggtcc caaacaaccc 7140 cggctgctgt ggtaaagagc catggtagtg agcgcagggg gaacgatcag acgagatctg 7200 atcctatgtg agatt 7215 <210> 1409 <211> 703 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(68..2176) <400> 1409 Met Ser Thr Gly Leu Arg Phe Thr Leu Glu Val Asp Gly Leu Pro Pro 1 5 10 15 Asp Ala Phe Ala Val Val Ser Phe His Leu Asn Gln Ser Leu Ser Ser 20 25 30 Leu Phe Ser Leu Asp Leu Ser Leu Val Ser Gln Gln Phe Leu Ser Leu 35 40 45 Glu Phe Ala Gln Val Leu Asp Lys Met Ala Tyr Leu Thr Val Trp Gln 50 55 60 Gly Asp Asp Val Gln Arg Arg Val Lys Gly Val Val Thr Trp Phe Glu 65 70 75 80 Leu Gly Glu Asn Asp Lys Asn Gln Met Leu Tyr Ser Met Lys Val Cys 85 90 95 Pro Pro Leu Trp Arg Thr Gly Leu Arg Gln Asn Phe Arg Ile Phe Gln 100 105 110 Asn Glu Asp Ile Glu Ser Ile Leu Ala Thr Ile Leu Lys Glu Asn Gly 115 120 125 Val Thr Glu Trp Ser Pro Leu Phe Ser Glu Pro His Pro Ser Arg Glu 130 135 140 Phe Cys Val Gln Tyr Gly Glu Thr Asp Tyr Asp Phe Leu Cys Arg Met 145 150 155 160 Ala Ala Glu Glu Gly Ile Phe Phe Tyr Glu Glu His Ala Gln Lys Ser 165 170 175 Ile Asp Gln Ser Leu Val Leu Cys Asp Thr Val Arg Tyr Leu Pro Glu 180 185 190 Ser Phe Glu Ile Pro Trp Asn Pro Asn Thr Arg Thr Glu Val Ser Thr 195 200 205 Leu Cys Ile Ser Gln Phe Arg Tyr Ser Ala Gln Ile Arg Pro Ser Ser 210 215 220 Val Val Thr Lys Asp Tyr Thr Phe Lys Arg Pro Gly Trp Ala Gly Arg 225 230 235 240 Phe Asp Gln Glu Gly Gln Tyr Gln Asp Tyr Gln Arg Thr Gln Tyr Glu 245 250 255 Val Tyr Asp Tyr Pro Gly Arg Phe Lys Gly Ala His Gly Gln Asn Phe 260 265 270 Ala Arg Trp Gln Met Asp Gly Trp Arg Asn Asn Ala Glu Val Ala Arg 275 280 285 Gly Thr Ser Arg Ser Pro Glu Ile Trp Pro Gly Arg Arg Ile Val Leu 290 295 300 Thr Gly His Pro Gln Ala Asn Leu Asn Arg Glu Trp Gln Val Val Ala 305 310 315 320 Ser Glu Leu His Gly Glu Gln Pro Gln Ala Val Pro Gly Arg Arg Gly 325 330 335 Ser Gly Thr Thr Leu Asn Asn His Phe Ala Val Ile Pro Ala Asp Arg 340 345 350 Thr Trp Arg Pro Gln Pro Leu Leu Lys Pro Leu Val Asp Gly Pro Gln 355 360 365 Ser Ala Val Val Thr Gly Pro Ala Gly Glu Glu Ile Phe Cys Asp Glu 370 375 380 His Gly Arg Val Arg Val Lys Phe Asn Trp Asp Arg Tyr Asn Pro Ser 385 390 395 400 Asn Gln Asp Ser Ser Cys Trp Ile Arg Val Ala Gln Ala Trp Ala Gly 405 410 415 Thr Gly Phe Gly Asn Leu Ala Ile Pro Arg Val Gly Gln Glu Val Ile 420 425 430 Val Asp Phe Leu Asn Gly Asp Pro Asp Gln Pro Ile Ile Met Gly Arg 435 440 445 Thr Tyr His Gln Glu Asn Arg Thr Pro Gly Ser Leu Pro Gly Thr Lys 450 455 460 Thr Gln Met Thr Ile Arg Ser Lys Asn Tyr Lys Gly Ser Gly Phe Asn 465 470 475 480 Glu Leu Lys Phe Asp Asp Ala Thr Gly Lys Glu Gln Val Tyr Ile His 485 490 495 Ala Gln Lys Asn Met Asn Thr Glu Val Leu Asn Asn Arg Thr Thr Asp 500 505 510 Val Ile Asn Asn His Ala Glu Thr Ile Gly Asn Asn Gln Met Ile Ala 515 520 525 Val Thr Asn Asn Gln Ile Gln Thr Val Gly Val Asn Gln Ile Glu Thr 530 535 540 Val Gly Ser Asn Gln Ile Ile Asn Val Gly Ser Val Gln Val Glu Thr 545 550 555 560 Ile Gly Leu Val Arg Ala Leu Thr Val Gly Val Ala Tyr Gln Thr Thr 565 570 575 Val Gly Gly Ile Met Asn Thr Ser Val Ala Leu Met Gln Ser Ser Gln 580 585 590 Ile Gly Leu His Lys Ser Leu Arg Val Gly Leu Gly Tyr Asp Val Lys 595 600 605 Val Gly Asn Asn Val Thr Phe Thr Val Gly Lys Thr Lys Lys Asp Asp 610 615 620 Thr Gly Gln Thr Ala Ile Tyr Ser Ala Gly Glu His Leu Glu Leu Cys 625 630 635 640 Cys Gly Lys Ala Arg Leu Val Leu Thr Lys Asp Gly Gln Ile Phe Leu 645 650 655 Asn Gly Thr Lys Ile His Leu Gln Gly Lys Glu Gln Val Asn Gly Asp 660 665 670 Ser Leu Leu Ile Asn Trp Asn Cys Ala Ala Ser Lys Ser Pro Pro Lys 675 680 685 Thr Pro Asp Glu Lys Gln Asp Thr Pro Asp Met Arg Glu Tyr * 690 695 700 <210> 1410 <211> 1401 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2243..6445) <400> 1410 Met Ser Gly Lys Pro Ala Ala Arg Gln Gly Asp Met Thr Gln Tyr Gly 1 5 10 15 Gly Pro Ile Val Gln Gly Ser Ala Gly Val Arg Ile Gly Ala Pro Thr 20 25 30 Gly Val Ala Cys Ser Val Cys Pro Gly Gly Met Thr Ser Gly Asn Pro 35 40 45 Val Asn Pro Leu Leu Gly Ala Lys Val Leu Pro Gly Glu Thr Asp Leu 50 55 60 Ala Leu Pro Gly Pro Leu Pro Phe Ile Leu Ser Arg Thr Tyr Ser Ser 65 70 75 80 Tyr Arg Thr Arg Thr Pro Ala Pro Val Gly Ile Phe Gly Pro Gly Trp 85 90 95 Lys Ala Pro Ser Asp Ile Arg Leu Gln Leu Arg Asp Asp Ala Leu Val 100 105 110 Leu Asn Asp Asn Gly Gly Arg Ser Ile His Phe Glu Pro Leu Leu Pro 115 120 125 Gly Glu Ala Val Tyr Ser Arg Ser Glu Ser Met Trp Leu Val Arg Gly 130 135 140 Gly Lys Ala Ala Gln Pro Asp Gly His Thr Leu Ala Arg Leu Trp Gly 145 150 155 160 Ala Leu Pro Pro Asp Ile Arg Leu Ser Pro His Leu Tyr Leu Ala Thr 165 170 175 Asn Ser Ala Gln Gly Pro Trp Trp Ile Leu Gly Trp Ser Glu Arg Val 180 185 190 Pro Gly Ala Glu Asp Val Leu Pro Ala Pro Leu Pro Pro Tyr Arg Val 195 200 205 Leu Thr Gly Met Ala Asp Arg Phe Gly Arg Thr Leu Thr Tyr Arg Arg 210 215 220 Glu Ala Ala Gly Asp Leu Ala Gly Glu Ile Thr Gly Val Thr Asp Gly 225 230 235 240 Ala Gly Arg Glu Phe Arg Leu Val Leu Thr Thr Gln Ala Gln Arg Ala 245 250 255 Glu Glu Ala Arg Lys Gln His Thr Ala Ser Leu Ser Ser Pro Asp Thr 260 265 270 Pro Arg Pro Leu Ser Asp Ser Ala Phe Pro Asp Thr Leu Pro Gly Thr 275 280 285 Glu Tyr Gly Pro Asp Arg Gly Ile Arg Leu Ser Ala Val Trp Leu Thr 290 295 300 His Asp Pro Ala Tyr Pro Glu Ser Leu Pro Gly Ala Pro Leu Ala Arg 305 310 315 320 Tyr Thr Tyr Thr Glu Ala Gly Glu Leu Leu Ala Val Tyr Asp Arg Ser 325 330 335 Asn Thr Gln Val Arg Ala Phe Thr Tyr Asp Ala Gln His Pro Gly Arg 340 345 350 Met Val Ala His Arg Tyr Ala Gly Arg Pro Glu Met Arg Tyr Arg Tyr 355 360 365 Asp Asp Thr Gly Arg Val Val Glu Gln Leu Asn Pro Ala Gly Leu Ser 370 375 380 Tyr Arg Tyr Gln Tyr Glu Gln Asp Arg Ile Thr Val Thr Asp Ser Leu 385 390 395 400 Asn Arg Arg Glu Val Leu His Thr Glu Gly Gly Ala Gly Leu Lys Arg 405 410 415 Val Val Lys Lys Glu Leu Ala Asp Gly Ser Val Thr His Ser Gly Tyr 420 425 430 Asp Ala Ala Gly Arg Leu Thr Ala Gln Thr Asp Ala Ala Gly Arg Arg 435 440 445 Thr Glu Tyr Gly Leu Asn Val Val Ser Gly Asp Ile Thr Asp Ile Thr 450 455 460 Thr Pro Asp Gly Arg Glu Thr Lys Phe Tyr Tyr Asn Asp Gly Asn Gln 465 470 475 480 Leu Thr Ala Val Val Ser Pro Asp Gly Leu Glu Ser Arg Arg Ala Tyr 485 490 495 Asp Glu Pro Gly Arg Leu Val Ser Glu Thr Ser Arg Cys Gly Asp Val 500 505 510 Ile Arg Tyr Ala Tyr Asp Asn Pro His Ser Glu Leu Pro Ala Thr Thr 515 520 525 Thr Asp Ala Thr Gly Ser Thr Arg Gln Met Thr Trp Ser Arg Tyr Gly 530 535 540 Gln Leu Leu Ala Phe Thr Asp Cys Ser Gly Tyr Gln Thr Arg Tyr Glu 545 550 555 560 Tyr Asp Arg Phe Gly Gln Met Thr Ala Val His Arg Glu Glu Gly Ile 565 570 575 Ser Arg Tyr Arg Arg Tyr Asp Asn Arg Gly Arg Leu Thr Ser Val Lys 580 585 590 Asp Ala Gln Gly His Glu Thr Arg Tyr Glu Tyr Asn Ala Ala Gly Asp 595 600 605 Leu Thr Ala Val Ile Thr Pro Asp Gly Asn Arg Ser Glu Thr Gln Tyr 610 615 620 Asp Ala Trp Gly Lys Ala Val Ser Thr Thr Gln Gly Gly Leu Thr Arg 625 630 635 640 Ser Met Glu Tyr Asp Leu Ala Gly Arg Ile Thr Thr Leu Thr Asn Glu 645 650 655 Asn Gly Ser Arg Ser Glu Phe Thr Tyr Asp Ala Leu Asp Arg Leu Val 660 665 670 Gln Gln Arg Gly Phe Asp Gly Arg Thr Gln Arg Tyr His Tyr Asp Leu 675 680 685 Thr Gly Lys Leu Thr Gln Ser Glu Asp Glu Gly Leu Val Thr Leu Trp 690 695 700 His Tyr Asp Glu Ser Asp Arg Leu Thr His Arg Thr Val Asn Gly Glu 705 710 715 720 Pro Ala Glu Gln Trp Gln Tyr Asp Glu His Gly Trp Leu Thr Glu Ile 725 730 735 Ser His Leu Ser Glu Gly His Gln Val Ala Val His Tyr Gly Tyr Asp 740 745 750 Asp Lys Gly Arg Leu Ala Gly Glu Arg Gln Thr Val His Asn Pro Glu 755 760 765 Thr Gly Glu Leu Leu Trp Gln His Glu Thr Glu His Ala Tyr Asn Glu 770 775 780 Gln Gly Leu Ala Asn Arg Val Thr Pro Asp Ser Leu Pro Arg Val Glu 785 790 795 800 Trp Leu Thr Tyr Gly Ser Gly Tyr Leu Ala Gly Met Lys Leu Gly Gly 805 810 815 Thr Pro Leu Val Glu Phe Thr Arg Asp Arg Leu His Arg Glu Thr Val 820 825 830 Arg Ser Phe Gly Asn Asn Ala Tyr Glu Leu Thr Ser Thr Tyr Thr Pro 835 840 845 Ala Gly His Leu Gln Ser Gln Arg Leu Asn Ser Gln Val Tyr Asp Arg 850 855 860 Asp Tyr Asp Trp Asn Asp Asn Gly Asp Leu Val Arg Ile Ser Gly Pro 865 870 875 880 Arg Gln Thr Trp Glu Tyr Gly Tyr Ser Ala Thr Gly Arg Leu Glu Ser 885 890 895 Val Arg Thr Leu Ala Ser Asp Leu Asp Ile Arg Ile Pro Tyr Ala Thr 900 905 910 Asp Pro Ala Gly Asn Arg Leu Pro Asp Pro Glu Leu His Pro Asp Ser 915 920 925 Thr Leu Thr Ala Trp Pro Asp Asn Arg Ile Ala Glu Asp Ala His Tyr 930 935 940 Val Tyr Arg His Asp Glu Tyr Gly Arg Leu Thr Glu Lys Thr Asp Arg 945 950 955 960 Ile Pro Ala Gly Val Ile Arg Thr Asp Asp Glu Arg Thr His His Tyr 965 970 975 His Tyr Asp Ser Gln His Arg Leu Val Phe Tyr Thr Arg Ile Gln His 980 985 990 Gly Glu Pro Leu Val Glu Ser Arg Tyr Leu Tyr Asp Pro Leu Gly Arg 995 1000 1005 Arg Met Ala Lys Arg Val Trp Arg Arg Glu Arg Asp Leu Thr Gly Trp 1010 1015 1020 Met Ser Leu Ser Arg Lys Pro Glu Val Thr Trp Tyr Gly Trp Asp Gly 1025 1030 1035 1040 Asp Arg Leu Thr Thr Val Gln Thr Asp Thr Thr Arg Ile Gln Thr Val 1045 1050 1055 Tyr Glu Pro Gly Ser Phe Thr Pro Leu Ile Arg Val Glu Thr Glu Asn 1060 1065 1070 Gly Glu Arg Glu Lys Ala Gln Arg Arg Ser Leu Ala Glu Thr Leu Gln 1075 1080 1085 Gln Glu Gly Ser Glu Asn Gly His Gly Val Val Phe Pro Ala Glu Leu 1090 1095 1100 Val Arg Leu Leu Asp Arg Leu Glu Glu Glu Ile Arg Ala Asp Arg Val 1105 1110 1115 1120 Ser Ser Glu Ser Arg Ala Trp Leu Ala Gln Cys Gly Leu Thr Val Glu 1125 1130 1135 Gln Leu Ala Arg Gln Val Glu Pro Glu Tyr Thr Pro Ala Arg Lys Val 1140 1145 1150 His Phe Tyr His Cys Asp His Arg Gly Leu Pro Leu Ala Leu Ile Ser 1155 1160 1165 Glu Asp Gly Asn Thr Ala Trp Arg Gly Glu Tyr Asp Glu Trp Gly Asn 1170 1175 1180 Gln Leu Asn Glu Glu Asn Pro Tyr Tyr Leu His Gln Pro Tyr Arg Leu 1185 1190 1195 1200 Pro Gly Gln Gln His Asp Glu Glu Ser Gly Leu Tyr Tyr Asn Arg Asn 1205 1210 1215 Arg Tyr Tyr Asp Pro Leu Gln Gly Arg Tyr Ile Thr Gln Asp Pro Ile 1220 1225 1230 Gly Leu Ala Gly Gly Trp Asn Leu Tyr Asn Tyr Pro Leu Asn Pro Ile 1235 1240 1245 Ile Arg Met Asp Pro Leu Gly Leu Tyr Asn Leu Tyr Gln Leu Leu Tyr 1250 1255 1260 Asp Val Trp His Asp Asp Ser Tyr Gly Thr Ser Ser Ile Asp Ile Thr 1265 1270 1275 1280 Gly Ser Gly Asp Leu Ile Ser Leu Gly Gly His Ala Gly Leu Gly Val 1285 1290 1295 Ala Phe Ala Lys Lys Lys Gly Glu Met Leu Ser Asp Ile Cys Ile Tyr 1300 1305 1310 Ala Thr Ala Cys Gly His Ala Gly Ile Gly Gly Gly Ile Asn Ala Ala 1315 1320 1325 Ile Thr Tyr Ser Tyr Ser Lys Ser Leu Pro Thr Ser Gly Val Ser Asn 1330 1335 1340 Ser Val Gly Val Thr Val Gly Gly Gly Val Gly Gly His Phe Ala Tyr 1345 1350 1355 1360 Thr Tyr Val Val Asp Val Asp Asn Pro Glu Ser Ser Thr Glu Ser Val 1365 1370 1375 Gly Ile Gly Ala Gly Val Asp Ala Ser Val Met Thr Leu Ala Cys Arg 1380 1385 1390 Thr Trp Gln Glu Cys Trp Val Asn * 1395 1400 <210> 1411 <211> 6943 <212> DNA <213> Escherichia coli O157:H7 <400> 1411 cccaaaggaa agttattact tattgatatt gaaggggaaa aatatcagca ttttttcatg 60 aaaggagagg aaatatgaac ggctgtcata aaacagccgc aaaaggttag tttacaaatt 120 caatggttaa ggtcgcggta gcgttaaaaa cgccgggctg aggccgggca ccggtaaagc 180 tggcaggtgc tgccgaaaaa gttaccgaac catttttacg accaaaaatg gtcgtgttgc 240 ccatgtctgc gggtaacttg ccgttgttga cgctaacttc agcattcgat ttattgtaaa 300 ttttgatccc gacatcagca ttgtctgtcg ccaccatcgt atcgtcactg cttcggttcg 360 tccccgtaaa agaagcatcg actttctgcg tacgctcata ccccatcccc gtacactcaa 420 tactcactgt tttagtgatt tttcgtgaag taatggcttg cccggcggta gatgaaaatt 480 cggacgcagg aatagtatca aaatcaaaat aaatcacctg tcctgcattt atctgacaag 540 actgtggtgc ggtcaaactg cctgaaattc gaacttttgc aatcgcctca ccacgggtcg 600 tggtgctgga tatgttggca tacagcaatg caatatcggt gataggtatt actaccgttc 660 catttattga acgtttaata cgaaatgaaa tcttcgcatc tgctccagtt ttcaggctca 720 cgccaaccgc tgtagttttg tttccctgac aagtgtgatc tgttgtagtt gcctggttgg 780 aaacatgttc aaaaggaact gccgtatacc ccgcatttag cacagatatt tttgttccca 840 catcgacata ttcgttaaga tagtaaaaag caagaccact tgcggtggtg ctataaacca 900 taccgggagc agggtctgcg gtataatata tttcgtgata agcgccattg ctatgttttg 960 aatcacagtt acacagaacg ctataatttt cagaagatgt tgcattagca atatctatta 1020 atgtatttcc aggcacattg tttgctgcac tgaccgttgt cagaggaaaa ttaaggctta 1080 atgtatgtgt gccgcctctt gttgcacacg tgccatcatt tgccgcatac ccgcacggta 1140 accctaaatg aaagagaatt atgcaaaata tataatgcca ttttttcatg aaattattcc 1200 ttttactaac acaagattag ttagtaaatt caataaccag cgtggctgta gcggtaaatc 1260 cattatcagg cgctggtttt gcgcccgtca gactggcggg cgctgaataa aacgttacgc 1320 taccatcggt ttttcctaat cgactaatag cacccatatc agcgggtaag ttgcccccat 1380 ccacattcac tggacggtcg ttcttatcaa aaatcttaat tcccacatcc ggattactcg 1440 tcacgatcat ggtggcatcg gcacttctgt ttgccgcaat catcgacgca ctcaccacct 1500 ccgtggacct tacgtcttcc atcccggtac aggatactgt gacttcggtt ttaatctttc 1560 tttctgcaat aattgaaccc gccgttgagg agaactcagc gctattaatt ttttgaaaat 1620 cgacatcgat gctctgattt ggcgttaact cacagttctg cggggccgtt agttgtccgc 1680 gaattgtcac tttagaaacg ggggtcgttt tgggaaaatg atcggacatg cccgcgtaca 1740 accaggcgac ttccgttgtg ggtattgtca ccgtgccagt aatagaatgc cgaacataga 1800 aagataattt tgccgagcgc cctgaatcca gatttacagt gctcccatta ttacctgctc 1860 cacaggtatg ttgcggtgag gtggattggt tggataagtg ttcaaaagga atggccgcat 1920 attggttatt aataataaaa atcgtcacgc cgaccgataa ataatcattc agagcatagt 1980 aatttaaccc attaagagtg cgctcaagca caagccccgg tgcggcatct cccgtgtaga 2040 agataggaaa aaatgctgtt tgttggcccg gtccgccatg cgtgtcatca cagtgacagc 2100 gcaccgggta tgttccagtc gtgttgctca gtgcctcgaa aatattgtat ccggagtggt 2160 tattcgccgc tgccaccgtc agcggaccaa atgataaatt tgacatgtgc gttgcgccat 2220 caccattagc ggcgaaacca taaggacagc aaagcagcag aatcaaccct gataatattt 2280 ttttcattca tgcttccttt agcgacaaat cgcatccatt tgaaccaggc tggtatcatc 2340 aggtttatgg gtgatgtgat aggccgcctt acatttttca tccgcagctt gtccccaact 2400 caataaaaac tcgccttttt caggcatccc ggagagatac agttcgccgt tatcaccgac 2460 aatcccggtg actgtgcccg tttcgagaga ggcggttgcc atcgcgccaa acattattgg 2520 tttaccgttg acctggcgga cgttaaatag cacgcgataa ccgacatggg tgacaaattc 2580 ggctttcacc accgcaccgc gcgttggtac caggttgatg acggtgtttt ccagttcaat 2640 attggctttg gagaaatagt cgctgttcaa tgccacgcgg ttttcgtcat acgggctaag 2700 ctgcgttttt acggtataac cacgccagtc ggtagaaatc ccggtggcgt tttcaatgga 2760 caggccttct gcgcccggcg ctttgaccaa tgccaccgtt tcgcccagtt cctgcgagaa 2820 ggtcactccg tcactatgca ccagcacgcc gcctctggcg ccataatcaa aatgttggga 2880 gtcacggctc caggaatagc taccattgac cgagccataa gtcccgtcat aggtcattcc 2940 ggcattgccg ctgtaggagt catcaggaga gtgcatccac gattcctgta cgttataaga 3000 caggttacgc ccttccagca tcgttccgtt cagaccgacc tgcatcgtgc tttcatggtg 3060 gttgttttgc gttaacgaat agttgacgta gctgtcttcc atccagcacg atagcggtat 3120 cgacattgag aacatgaaaa tctgttcttt gccgaaatca tcattgttat catcatgatg 3180 gttgcccaat gagcgcttga tcgagtccgt atagttccag gaaacgttcc aggagatgtt 3240 tcgccagttg ttgttatagc cgaactgtaa taaacgttcg acctcatcgg tctgccagta 3300 ttcctgtcga ctgaatgtta aataaatatt gccccagcct ggcgtgaaag attgcgtcca 3360 ggtgccttcg aagcggctgc gacggttgcc cgttacccag aaatcagaat cattatcctg 3420 tcgcgacacc cattcattga gggtgtagaa cccctccata gagtagcgat aacccaccag 3480 acgaaaggtg gtattggtgt cttcaaaacg tttggaatag agaaaacgat acgattgacc 3540 actctcatta tcgtcgtagt caaactgcga gcgggcatga gtcacgtcaa aagaaatcgc 3600 gcccagcgcc cccatatctt taccaatacc cagcgcggca gaagcgtaat catttgccaa 3660 ttgtgttccg ccatacaaag ttattcccaa agggaaaccg tgcattgctt gtaactgcaa 3720 gacctcaggc gtaaagccgc tttcgtcgcg cacttctcca atgctaaggt ctacatcggt 3780 ctgaccttca cgcttgagaa tggccagtga agtaaatggc tgaataaagt gctgctcgct 3840 gccatcttct tctttgatag tgacatcgag atcgccgccg ctactggtcg tgtttaagtc 3900 ggtgagggca aatgcgccct gtggtacggc tgattgataa ataacgtagc cgttttgttt 3960 gatgatcacc gtggcgttag ttttcgcaat cccatgtacc actggcgcaa agccgttctg 4020 gctggagggc aacatatcgt catcggtata cagccgcacg ccacgcacct gtgtactatc 4080 aaatacatcg cttgccgtcc aggtatcgcc aatcataatc tggctacgta atgccatgat 4140 gtcgcgctga atgtaattac tgacggaatg gtagtccaca ttaccgtcat aagaattcag 4200 ggtgctgtaa ttacgaaaac gccatgcgcc taaattaata ccattacgca aattcagata 4260 ataactgtca tcgtcgtcgt cataatttga ccggatggta tgcgatgccg aaaaatcata 4320 attcatcatc atggcattga tcccctgatc ccaacgggaa gggctgatat aaccattaac 4380 tgcattgttg agataaattt gcggaatagt aatattcaat gcaagtttac tggcgtccag 4440 taaccaggta gccccgtcga tcagcggaac tggatttacg catgttttgt catcaacatt 4500 cgccagagat tttatcgcat caacttttat accataggtc gccagcacgt tttttatcgc 4560 cacgtagcat gggtggagtt cagcatcagg gttatcctgg gcgaatttaa cttcctggcg 4620 ttcgaagagc atgccgttga tcatcacatc aactttgtat gttcccgcag gtaaggtatt 4680 cgaacggttg aactggtgaa tatcaatatt atccgcagga tgatccagtt ccagtaatct 4740 ggggttgaac aagctatccc gggcaaaagc agatatggaa cagagcagac atatgcccga 4800 tgcaagcgta atgaaaagat gcgaagaggc catcgatata tccttatccg gcgcttaaag 4860 gtttttcttt agtggttgac taattgcacc gtaatcatta ataaagcgcc aaacgagcga 4920 ttttcctgcc acgccagccg gaattggtaa tgtcaatatt tcaaaagggc ggatcatatt 4980 tagcgacacg tctttatcat ccaccgtcac actcattaca ttaatatgga tcggatttgg 5040 attttcgacg atgagattat taccctgccg cgaccattta acatttttaa tagcctgctc 5100 agggattatc tttaccgcgg ctggtcgcca gaataactta attcttgttt ttatggctat 5160 ctcaagaaca ttggtatttt tttatcaatt gaaggaggga tgtttttcac gttcaaccag 5220 aatacggact cccgatcttt tggtaactcg ccagccgttt ttaaaatgcg taatattttc 5280 tcttgctgtg gttcaatgcg agaaacggga ggtatcacag aaaatggcgg tttgctttta 5340 tcctctttat taaatggatc aacccatgtc tgcaatagat aaggaaggtt cgtttcttta 5400 ttaaaaatag agattgtggt atcaggtttg tcaccataaa aaataacgcg agttccccca 5460 acaacaatac cagccgtagc catcgacatc tgcgtaatca aagtaacagc aaaaaacaat 5520 ctaagtaaat acataggcat aaatgtatct cataaaaaat ataataatga cgcccttcat 5580 ttaagtaaaa gagaaccata atggcgagcg ccattttatt taaggtatta tgttaagaat 5640 gatttatttt atatattcaa ctgtaaactg cgagtcggcg ttagctgtac cagggtcaat 5700 agtcgtttcc gtagcaatat aacgagccat gaacttcatg gatgcattac cattagaaat 5760 cggagttgat gcagaatttt catataactt gacctgagtg ttatctgcac ggttatataa 5820 acgaatagct acgcctttcg ctgcactaac ggcacccgca ccagtataat ccccactgtt 5880 atcactcggg ctaataccag cggcagcatc gttagagtta tccagcgggg taccaattgc 5940 caggttgcca ttaccatgag catcttcatt accatcgaaa cgaattgcgg cggacttaaa 6000 ggtttccggg cattgagtca gatcgataga aaaagccgtc ggggcagcca catcatcgac 6060 gccactaaag gctgtacggt ttactttgcc taaatcaacg acctgatctt tagtttcagg 6120 agtgacttcg caagtactgt caataatttc accacggaaa tggactgttc catcagccgc 6180 ctgtaggtga cctgccataa acacagaagt taacgctaat gctcctacaa tcatatttgg 6240 tttcataaat ataactccat taatttgata ttattcctgt gtgttatcca tttattaaat 6300 ttggataaac ctgatcggta tttgatcaga aaccaaatag tactaccaat atactttggc 6360 gcaagtggtt tttattttat acatttagat aaattaattt aggtgttaag caaaactaaa 6420 tttatatcgt tatgtgattg cttaaaagaa gagggaataa taaatggata taaatattat 6480 ttttatgatg aggtgatttt ttaattatat cacacatctc aaagcagaca attttttcat 6540 atttacataa tccacaacta tgaattcgcg tagaaaacag tcttattttt agtaaaccac 6600 actttcaaat tatatttttt gcctatattt gtggaaagac tatacattta cagtgataat 6660 ttattatcac acattgttac atagttaaat aaaattacat attgatgatt gttttacaag 6720 cgattcttga atgaacaaaa cgtgctattc attacaaagt acatcaatta tggcaattgt 6780 ttgtcaatga ttcgaggtat ttaattacta ctacggttaa aacaagtgtt caacggtgcc 6840 ccaaataata gctgaagtta attatatgga atgaggttag attattaatg ctggtaagta 6900 aaagggccgc caaaaggcag cccttcgttc agcaaatgaa taa 6943 <210> 1412 <211> 361 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(107..1189) <400> 1412 Met Lys Lys Trp His Tyr Ile Phe Cys Ile Ile Leu Phe His Leu Gly 1 5 10 15 Leu Pro Cys Gly Tyr Ala Ala Asn Asp Gly Thr Cys Ala Thr Arg Gly 20 25 30 Gly Thr His Thr Leu Ser Leu Asn Phe Pro Leu Thr Thr Val Ser Ala 35 40 45 Ala Asn Asn Val Pro Gly Asn Thr Leu Ile Asp Ile Ala Asn Ala Thr 50 55 60 Ser Ser Glu Asn Tyr Ser Val Leu Cys Asn Cys Asp Ser Lys His Ser 65 70 75 80 Asn Gly Ala Tyr His Glu Ile Tyr Tyr Thr Ala Asp Pro Ala Pro Gly 85 90 95 Met Val Tyr Ser Thr Thr Ala Ser Gly Leu Ala Phe Tyr Tyr Leu Asn 100 105 110 Glu Tyr Val Asp Val Gly Thr Lys Ile Ser Val Leu Asn Ala Gly Tyr 115 120 125 Thr Ala Val Pro Phe Glu His Val Ser Asn Gln Ala Thr Thr Thr Asp 130 135 140 His Thr Cys Gln Gly Asn Lys Thr Thr Ala Val Gly Val Ser Leu Lys 145 150 155 160 Thr Gly Ala Asp Ala Lys Ile Ser Phe Arg Ile Lys Arg Ser Ile Asn 165 170 175 Gly Thr Val Val Ile Pro Ile Thr Asp Ile Ala Leu Leu Tyr Ala Asn 180 185 190 Ile Ser Ser Thr Thr Thr Arg Gly Glu Ala Ile Ala Lys Val Arg Ile 195 200 205 Ser Gly Ser Leu Thr Ala Pro Gln Ser Cys Gln Ile Asn Ala Gly Gln 210 215 220 Val Ile Tyr Phe Asp Phe Asp Thr Ile Pro Ala Ser Glu Phe Ser Ser 225 230 235 240 Thr Ala Gly Gln Ala Ile Thr Ser Arg Lys Ile Thr Lys Thr Val Ser 245 250 255 Ile Glu Cys Thr Gly Met Gly Tyr Glu Arg Thr Gln Lys Val Asp Ala 260 265 270 Ser Phe Thr Gly Thr Asn Arg Ser Ser Asp Asp Thr Met Val Ala Thr 275 280 285 Asp Asn Ala Asp Val Gly Ile Lys Ile Tyr Asn Lys Ser Asn Ala Glu 290 295 300 Val Ser Val Asn Asn Gly Lys Leu Pro Ala Asp Met Gly Asn Thr Thr 305 310 315 320 Ile Phe Gly Arg Lys Asn Gly Ser Val Thr Phe Ser Ala Ala Pro Ala 325 330 335 Ser Phe Thr Gly Ala Arg Pro Gln Pro Gly Val Phe Asn Ala Thr Ala 340 345 350 Thr Leu Thr Ile Glu Phe Val Asn * 355 360 <210> 1413 <211> 357 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1217..2287) <400> 1413 Met Lys Lys Ile Leu Ser Gly Leu Ile Leu Leu Leu Cys Cys Pro Tyr 1 5 10 15 Gly Phe Ala Ala Asn Gly Asp Gly Ala Thr His Met Ser Asn Leu Ser 20 25 30 Phe Gly Pro Leu Thr Val Ala Ala Ala Asn Asn His Ser Gly Tyr Asn 35 40 45 Ile Phe Glu Ala Leu Ser Asn Thr Thr Gly Thr Tyr Pro Val Arg Cys 50 55 60 His Cys Asp Asp Thr His Gly Gly Pro Gly Gln Gln Thr Ala Phe Phe 65 70 75 80 Pro Ile Phe Tyr Thr Gly Asp Ala Ala Pro Gly Leu Val Leu Glu Arg 85 90 95 Thr Leu Asn Gly Leu Asn Tyr Tyr Ala Leu Asn Asp Tyr Leu Ser Val 100 105 110 Gly Val Thr Ile Phe Ile Ile Asn Asn Gln Tyr Ala Ala Ile Pro Phe 115 120 125 Glu His Leu Ser Asn Gln Ser Thr Ser Pro Gln His Thr Cys Gly Ala 130 135 140 Gly Asn Asn Gly Ser Thr Val Asn Leu Asp Ser Gly Arg Ser Ala Lys 145 150 155 160 Leu Ser Phe Tyr Val Arg His Ser Ile Thr Gly Thr Val Thr Ile Pro 165 170 175 Thr Thr Glu Val Ala Trp Leu Tyr Ala Gly Met Ser Asp His Phe Pro 180 185 190 Lys Thr Thr Pro Val Ser Lys Val Thr Ile Arg Gly Gln Leu Thr Ala 195 200 205 Pro Gln Asn Cys Glu Leu Thr Pro Asn Gln Ser Ile Asp Val Asp Phe 210 215 220 Gln Lys Ile Asn Ser Ala Glu Phe Ser Ser Thr Ala Gly Ser Ile Ile 225 230 235 240 Ala Glu Arg Lys Ile Lys Thr Glu Val Thr Val Ser Cys Thr Gly Met 245 250 255 Glu Asp Val Arg Ser Thr Glu Val Val Ser Ala Ser Met Ile Ala Ala 260 265 270 Asn Arg Ser Ala Asp Ala Thr Met Ile Val Thr Ser Asn Pro Asp Val 275 280 285 Gly Ile Lys Ile Phe Asp Lys Asn Asp Arg Pro Val Asn Val Asp Gly 290 295 300 Gly Asn Leu Pro Ala Asp Met Gly Ala Ile Ser Arg Leu Gly Lys Thr 305 310 315 320 Asp Gly Ser Val Thr Phe Tyr Ser Ala Pro Ala Ser Leu Thr Gly Ala 325 330 335 Lys Pro Ala Pro Asp Asn Gly Phe Thr Ala Thr Ala Thr Leu Val Ile 340 345 350 Glu Phe Thr Asn * 355 <210> 1414 <211> 845 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2299..4833) <400> 1414 Met Ala Ser Ser His Leu Phe Ile Thr Leu Ala Ser Gly Ile Cys Leu 1 5 10 15 Leu Cys Ser Ile Ser Ala Phe Ala Arg Asp Ser Leu Phe Asn Pro Arg 20 25 30 Leu Leu Glu Leu Asp His Pro Ala Asp Asn Ile Asp Ile His Gln Phe 35 40 45 Asn Arg Ser Asn Thr Leu Pro Ala Gly Thr Tyr Lys Val Asp Val Met 50 55 60 Ile Asn Gly Met Leu Phe Glu Arg Gln Glu Val Lys Phe Ala Gln Asp 65 70 75 80 Asn Pro Asp Ala Glu Leu His Pro Cys Tyr Val Ala Ile Lys Asn Val 85 90 95 Leu Ala Thr Tyr Gly Ile Lys Val Asp Ala Ile Lys Ser Leu Ala Asn 100 105 110 Val Asp Asp Lys Thr Cys Val Asn Pro Val Pro Leu Ile Asp Gly Ala 115 120 125 Thr Trp Leu Leu Asp Ala Ser Lys Leu Ala Leu Asn Ile Thr Ile Pro 130 135 140 Gln Ile Tyr Leu Asn Asn Ala Val Asn Gly Tyr Ile Ser Pro Ser Arg 145 150 155 160 Trp Asp Gln Gly Ile Asn Ala Met Met Met Asn Tyr Asp Phe Ser Ala 165 170 175 Ser His Thr Ile Arg Ser Asn Tyr Asp Asp Asp Asp Asp Ser Tyr Tyr 180 185 190 Leu Asn Leu Arg Asn Gly Ile Asn Leu Gly Ala Trp Arg Phe Arg Asn 195 200 205 Tyr Ser Thr Leu Asn Ser Tyr Asp Gly Asn Val Asp Tyr His Ser Val 210 215 220 Ser Asn Tyr Ile Gln Arg Asp Ile Met Ala Leu Arg Ser Gln Ile Met 225 230 235 240 Ile Gly Asp Thr Trp Thr Ala Ser Asp Val Phe Asp Ser Thr Gln Val 245 250 255 Arg Gly Val Arg Leu Tyr Thr Asp Asp Asp Met Leu Pro Ser Ser Gln 260 265 270 Asn Gly Phe Ala Pro Val Val His Gly Ile Ala Lys Thr Asn Ala Thr 275 280 285 Val Ile Ile Lys Gln Asn Gly Tyr Val Ile Tyr Gln Ser Ala Val Pro 290 295 300 Gln Gly Ala Phe Ala Leu Thr Asp Leu Asn Thr Thr Ser Ser Gly Gly 305 310 315 320 Asp Leu Asp Val Thr Ile Lys Glu Glu Asp Gly Ser Glu Gln His Phe 325 330 335 Ile Gln Pro Phe Thr Ser Leu Ala Ile Leu Lys Arg Glu Gly Gln Thr 340 345 350 Asp Val Asp Leu Ser Ile Gly Glu Val Arg Asp Glu Ser Gly Phe Thr 355 360 365 Pro Glu Val Leu Gln Leu Gln Ala Met His Gly Phe Pro Leu Gly Ile 370 375 380 Thr Leu Tyr Gly Gly Thr Gln Leu Ala Asn Asp Tyr Ala Ser Ala Ala 385 390 395 400 Leu Gly Ile Gly Lys Asp Met Gly Ala Leu Gly Ala Ile Ser Phe Asp 405 410 415 Val Thr His Ala Arg Ser Gln Phe Asp Tyr Asp Asp Asn Glu Ser Gly 420 425 430 Gln Ser Tyr Arg Phe Leu Tyr Ser Lys Arg Phe Glu Asp Thr Asn Thr 435 440 445 Thr Phe Arg Leu Val Gly Tyr Arg Tyr Ser Met Glu Gly Phe Tyr Thr 450 455 460 Leu Asn Glu Trp Val Ser Arg Gln Asp Asn Asp Ser Asp Phe Trp Val 465 470 475 480 Thr Gly Asn Arg Arg Ser Arg Phe Glu Gly Thr Trp Thr Gln Ser Phe 485 490 495 Thr Pro Gly Trp Gly Asn Ile Tyr Leu Thr Phe Ser Arg Gln Glu Tyr 500 505 510 Trp Gln Thr Asp Glu Val Glu Arg Leu Leu Gln Phe Gly Tyr Asn Asn 515 520 525 Asn Trp Arg Asn Ile Ser Trp Asn Val Ser Trp Asn Tyr Thr Asp Ser 530 535 540 Ile Lys Arg Ser Leu Gly Asn His His Asp Asp Asn Asn Asp Asp Phe 545 550 555 560 Gly Lys Glu Gln Ile Phe Met Phe Ser Met Ser Ile Pro Leu Ser Cys 565 570 575 Trp Met Glu Asp Ser Tyr Val Asn Tyr Ser Leu Thr Gln Asn Asn His 580 585 590 His Glu Ser Thr Met Gln Val Gly Leu Asn Gly Thr Met Leu Glu Gly 595 600 605 Arg Asn Leu Ser Tyr Asn Val Gln Glu Ser Trp Met His Ser Pro Asp 610 615 620 Asp Ser Tyr Ser Gly Asn Ala Gly Met Thr Tyr Asp Gly Thr Tyr Gly 625 630 635 640 Ser Val Asn Gly Ser Tyr Ser Trp Ser Arg Asp Ser Gln His Phe Asp 645 650 655 Tyr Gly Ala Arg Gly Gly Val Leu Val His Ser Asp Gly Val Thr Phe 660 665 670 Ser Gln Glu Leu Gly Glu Thr Val Ala Leu Val Lys Ala Pro Gly Ala 675 680 685 Glu Gly Leu Ser Ile Glu Asn Ala Thr Gly Ile Ser Thr Asp Trp Arg 690 695 700 Gly Tyr Thr Val Lys Thr Gln Leu Ser Pro Tyr Asp Glu Asn Arg Val 705 710 715 720 Ala Leu Asn Ser Asp Tyr Phe Ser Lys Ala Asn Ile Glu Leu Glu Asn 725 730 735 Thr Val Ile Asn Leu Val Pro Thr Arg Gly Ala Val Val Lys Ala Glu 740 745 750 Phe Val Thr His Val Gly Tyr Arg Val Leu Phe Asn Val Arg Gln Val 755 760 765 Asn Gly Lys Pro Ile Met Phe Gly Ala Met Ala Thr Ala Ser Leu Glu 770 775 780 Thr Gly Thr Val Thr Gly Ile Val Gly Asp Asn Gly Glu Leu Tyr Leu 785 790 795 800 Ser Gly Met Pro Glu Lys Gly Glu Phe Leu Leu Ser Trp Gly Gln Ala 805 810 815 Ala Asp Glu Lys Cys Lys Ala Ala Tyr His Ile Thr His Lys Pro Asp 820 825 830 Asp Thr Ser Leu Val Gln Met Asp Ala Ile Cys Arg * 835 840 <210> 1415 <211> 54 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4855..5016) <400> 1415 Met Ser Val Thr Val Asp Asp Lys Asp Val Ser Leu Asn Met Ile Arg 1 5 10 15 Pro Phe Glu Ile Leu Thr Leu Pro Ile Pro Ala Gly Val Ala Gly Lys 20 25 30 Ser Leu Val Trp Arg Phe Ile Asn Asp Tyr Gly Ala Ile Ser Gln Pro 35 40 45 Leu Lys Lys Asn Leu * 50 <210> 1416 <211> 128 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5157..5540) <400> 1416 Met Pro Met Tyr Leu Leu Arg Leu Phe Phe Ala Val Thr Leu Ile Thr 1 5 10 15 Gln Met Ser Met Ala Thr Ala Gly Ile Val Val Gly Gly Thr Arg Val 20 25 30 Ile Phe Tyr Gly Asp Lys Pro Asp Thr Thr Ile Ser Ile Phe Asn Lys 35 40 45 Glu Thr Asn Leu Pro Tyr Leu Leu Gln Thr Trp Val Asp Pro Phe Asn 50 55 60 Lys Glu Asp Lys Ser Lys Pro Pro Phe Ser Val Ile Pro Pro Val Ser 65 70 75 80 Arg Ile Glu Pro Gln Gln Glu Lys Ile Leu Arg Ile Leu Lys Thr Ala 85 90 95 Gly Glu Leu Pro Lys Asp Arg Glu Ser Val Phe Trp Leu Asn Val Lys 100 105 110 Asn Ile Pro Pro Ser Ile Asp Lys Lys Ile Pro Met Phe Leu Arg * 115 120 125 <210> 1417 <211> 201 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5644..6246) <400> 1417 Met Lys Pro Asn Met Ile Val Gly Ala Leu Ala Leu Thr Ser Val Phe 1 5 10 15 Met Ala Gly His Leu Gln Ala Ala Asp Gly Thr Val His Phe Arg Gly 20 25 30 Glu Ile Ile Asp Ser Thr Cys Glu Val Thr Pro Glu Thr Lys Asp Gln 35 40 45 Val Val Asp Leu Gly Lys Val Asn Arg Thr Ala Phe Ser Gly Val Asp 50 55 60 Asp Val Ala Ala Pro Thr Ala Phe Ser Ile Asp Leu Thr Gln Cys Pro 65 70 75 80 Glu Thr Phe Lys Ser Ala Ala Ile Arg Phe Asp Gly Asn Glu Asp Ala 85 90 95 His Gly Asn Gly Asn Leu Ala Ile Gly Thr Pro Leu Asp Asn Ser Asn 100 105 110 Asp Ala Ala Ala Gly Ile Ser Pro Ser Asp Asn Ser Gly Asp Tyr Thr 115 120 125 Gly Ala Gly Ala Val Ser Ala Ala Lys Gly Val Ala Ile Arg Leu Tyr 130 135 140 Asn Arg Ala Asp Asn Thr Gln Val Lys Leu Tyr Glu Asn Ser Ala Ser 145 150 155 160 Thr Pro Ile Ser Asn Gly Asn Ala Ser Met Lys Phe Met Ala Arg Tyr 165 170 175 Ile Ala Thr Glu Thr Thr Ile Asp Pro Gly Thr Ala Asn Ala Asp Ser 180 185 190 Gln Phe Thr Val Glu Tyr Ile Lys * 195 200 <210> 1418 <211> 6796 <212> DNA <213> Escherichia coli O157:H7 <400> 1418 ccagaaattg cgaccttctt caacaaaccc ttcactgtag gcatattggg tatcaaacag 60 gttattgacc gacgcattga cgctgaagcc atgacctaag gtgtaatcgg ctcgaatgtg 120 ggtcaccgca aaaccggcgg ctttttgtga accgtcactg ttactgtagc tggaggaacg 180 cgcctcttcc gacagcgtta cgcttaacgg ctcccacggt ttgagagtca tccatgcggt 240 cattgtctgc gttggcagat cggttatctt gccgatgtct ttacgtttgg cgtcagcgtg 300 gatcagggcg tagctcaatc ctacatccag tatattgctg attttcccct taataccggc 360 atccagaccg ctgtaatcca ccgtgccgct gttctgattt tgaatggtat cggcatcgat 420 attgtgcgag aggatggcat cactcacccg gttatagtaa acgctgacct caaatcccca 480 gtcgtgcgtg aaggcaccat tccaggttaa atccaccccg cgagcgcgtt ccggcttgag 540 ctgcgggtta acaatcgcta tctggttata cgcaggtttg gatgtggtat agcgttcttt 600 cagcgtcgga aagcgtttgc ggtcatagta cgaaagcgcc agcgtgtctt cattgacaaa 660 gtggtatttc cccatcacct gccagttaaa agctgactga ttgttgtcgt cataatgggt 720 gatgctgcca tctttctcgt gttttttcgc ttctacgcta tcgcgccagt catagctgat 780 tccagccaca acatcgacat tatcggcagc agcccattga tattcactgg cgagcgacca 840 ggtacgatct tcatagcgat cgtaagcggc gtgcggcgca cctttttccc ggtgtacgtc 900 atctttccag ttaacggcaa acgtcagcag atcgttttca cgcacatcgg ctgccagttg 960 taatccggca ccgtcgctgt aatcggaata atggctgtag ctgccttttt tatttttcaa 1020 atcagccagc gagttgtaca tcatcagcgt attttcaaag gtgtcgcgat acagccgact 1080 tttcagggta aaacgatcgt ttagttgggt cgttccctga taataaaaac tttctttgtc 1140 atactctggc cactgccagt agcgtgattt ttgaccacta tttccgctgt atggcgggtt 1200 atctttttca ccatcctgct taatgtaagt cagtgtgtat tcatcgtttt cacgtggtgt 1260 aaatccgagc ttcacaatgc cgcgtttatc atcagccgat gaattaatca tcttgccgtg 1320 tttgcctgca atatcattat ttacaccatg cggcaggccg agaaaatcct gctttagctg 1380 gctaccgctg acttgcaaat accccagttc gctgctggcg gcaaatgaag catgcatatc 1440 ataggcattg tcctggctac ggctccatcc ctggcgatat cccagacttg cttccagagg 1500 ttttgttggc ttctgggtgg tgatattaat ggctccgccc atctgattag gtccctgaag 1560 cagcgacgaa taccctttgg aaacttcgac tgcccccaga ttgttggtca gaatccgcgc 1620 cagatcgagg ttgccgtcat agggaacata aatgggcaca ccgtcgaaat agaccggcac 1680 ctgccgacta tcaaagccac gaacttttac ctgttcttcg ttgcggctgc ctgacttttg 1740 cagcaccacg ccggggacga cacttaatgc ctgagcgaca ttctgtttat ccagggcctt 1800 catggtgggt tgatcgagaa cggtggtcgt cgtcgatgat accggactgg accatacggt 1860 cagcgagtcg ctctcctgag ccgctacggc ctgctgggta aaggcaagtg ataatgctgt 1920 gcagagataa tgttttttga gtctcataga ataaattccg tttaacaaag aattaaatag 1980 aggctgcggg ttgcagactg actttaatgt cagccggtgc cgcgtaataa ggcgcggagg 2040 taataaagag gcgaatgccg cagtcgaggt aatttttgag tgtcgtcaga ttaattccgc 2100 cggtcagagc cagcgtgcag tggggagcca gcgacggcgc tatttgcgca atttcagttg 2160 cctgttgcgg actaaatttg tcgagctgaa gtacgtctgg ttgcgcgcgt aacgcggcga 2220 ttgcctcttt cggcgtgtcg gcttcaacaa caattttctt ctcgggtgcg tggcgacgta 2280 actgattgat tgcgcctgac cagtcctgat tgtcatgaag aaaatggcgg tggttggcaa 2340 acaataatat ggtttccgca catccggcac gatgaatcag tcctccggca gccagaattg 2400 cctgcgaggc cagtaagcgg gtgcccggaa ttgcttttcg ggtgcaggcg atattgccat 2460 caggataacg ttcacgaagt aacgccagca tttgatcgag ataatcagaa acaccgcaac 2520 tccactccag cacattctgg attgccttcc atccctgatg aagtgctgcg gcattaccct 2580 gcgcacggat tagccgctga cccgcgttcg cttgtgaacc gtcgctgacc gcgtcatcaa 2640 tagttaatcc cagcgtagtt aacatcttac acgcgacaga aacgccgctg acgcagccgc 2700 cctgacggag aaaaaactct atatagccat gctggtgtcc aatatttaat gctctcgtgg 2760 tcaggtcacc gccctggata tcttccagaa gtaacgcatc gatttgtgcc tgagaaagga 2820 aaatcatcgc agtgcctcct gcggtacgct atcccaccag atgagcgccc agtcgcggct 2880 ggcaggggcg agggcacgag catcttgttg ttgataccag cgatataacc gctcacgctc 2940 atcgtcgtta agcgcgccaa gactccagct gacgttctgc tcaaaacgtt cctaggtgct 3000 gttatcctgt tggcaatttt gtccacggat aaaatcaacg tgggcataaa ttcccatctg 3060 atacaggacg ttgagcgcaa agatatagtt gggtaattcg atcacttccc gaccagccgc 3120 ccgctgaatg gctggagaga cgaacgaggt gctgaccaga tgagtcgtat agacgcgaag 3180 ccgtgcctga ttattcagtt tgctcattgc ctggcgcata tcagccacca gagtggagcg 3240 ggaagccacg gcaatatcgc agcgtggcag gtcactccag tcctcttccc aggcgcgctg 3300 gatcaagtgg acattgtctg ccttcagcgc ggcggcgcga cgggcggcaa cgttcagcat 3360 cccctgactg taatcaacgc cataaatcgt cgtgagtttg tcagccagcg ccagcgatac 3420 ggtacccggt ccgcagccca tatcgaataa ggtctgagcg ccttgtaggt caattttagc 3480 gatcagttgt tgcaggtagc tgtccgtagg cgaggcgcaa ttttccgcca ttttttccgc 3540 ccgttgatcc cagtgatccg gcgttttttc tgtgcggtgg gccagcttga gttgctgcag 3600 ataaaggtct gcaaaatcaa tatcatcaat gagcatgatt tttccttagt ggctaattgc 3660 agagaggtga tgatgaatct ggtcggcaga aacccgatac agggcagcca gtttgtttgt 3720 tgttaactgt tcggtcggta agccttgtgt tactcgtcca tctggctcta cctggataat 3780 gctgtcggca atggcgttgg catggagcgg atgatgagtc gacattaaca ttgtcatgcc 3840 gttatttttg agctgtgcca gcgtgtccag tagttggatc tgatgaccga aatcgaggct 3900 ggaggcaggc tcatccagta acaacaagcg cggttgctgg acgagtgcac gggcgattaa 3960 agccagctga cgttcaccgc cgctaagcgt attccagcgt cgtgccgcca gatgcaaaat 4020 gcccagcttt tccagttgct ccgtggcttt caggcgttct tgcttaccgg gaacggaaaa 4080 agcgcctatg gtgggggcca ggcccatcaa caccatatcc agcacactaa aagcaaaaat 4140 accgtcgtgc gcctgcggca cccaggcaat agcctgcgcg cgctggcgat ggctgagtgt 4200 ctgcacaggg aggctatcca gtaagacctc gccttttaat aacggtataa cgccaagaat 4260 ggagcgcatg agtgtggttt tgccgcaacc attggctcct aacagacaac aaattgttcc 4320 ttgcgacagg gtgaaggaca cgtcgcgtag caccggatgg cgggagtaac ccagagacgc 4380 atgacggacg gcaagcaaag tcactggcga cctccgcgta acaacaaaag caggaaaaac 4440 ggtgcgccaa caaaagcggt cagaatgcca agtgggattt ctgttgttcc aatgctgcgt 4500 gccagcgtat cggtaagcag gagcagaatc gcgccagtac acattgccat gggcaacagc 4560 tgctgatggt tatgaccggt caacaagcgg gcaatgtgcg gaacgaccag gccgacccaa 4620 ccaattatgc ccgctattgc taccgtactg gcggtgatta gtgtggcgca gacaatcaat 4680 acaaagcgca gacgcgtcac gttcagtccc agcgaacggg cttcgtcgtc ggaaagcgtg 4740 agtaaattca tgcgccagcg gagaaaaaac aggggcaagg agcctatgag aatgatcggt 4800 gcagcatagc agagatcgcg taaggtcacg gtggacagtc cccccagcaa ccagaaggta 4860 attgacggta actgggtgta aggatcggcc agcgttttaa ttagcgatat ccccgctccg 4920 cacaacgttc ctaacgcgat gcctaccagc accagggtta agatcggatc gtggcgggtc 4980 acccgacgcg taatcaacca gacgcccgcg accaccatca gcccgccaca aaatgcgtac 5040 agctggatgt aaacaatgga taatccccac agaattgccg tgcaggcacc aagtccggca 5100 ccggcggaga cgcctaaaat atccggtgaa actaagggat tacgcaacat tccctgatag 5160 gtggttccgg ctcctgccag cgccgcgccc agtaacagcg cagcaagaat acgcggcacg 5220 cggatttgcc agaagacaat ttgttcctgc acaggaacat tttcttgacg aagaattagc 5280 gccagcagtt gctgcatatc gagatgataa gccccactta cggcggcaaa agtgatactg 5340 atagctgcca gcagcaaaat acatccgttt acgattctca ttaggtcgcc accaattttt 5400 gatagtcggc gtcactgagt gaacaatgcc agaacagttg ggcgtaatgc tgcatgtcac 5460 ttttaaactg gcgattgatg gcgggatcca gccaggcgtg aagtctgcgt aatcccagaa 5520 gacggttgat tcccggtggg gcatccagcc agccaaaggg caagccactt aaaaataaga 5580 tgcgttgttc tgcaacggct ttcacgccat gccagagagg atcacgacga ataaaatctg 5640 cagtaacggc ctcctgaacc agaataatat ccggctgcca gcgcaggaga ttttccatgg 5700 aaacctgtgt caggccttgg cgatcggcta tttgcgcgac gttgtgcaaa cctaataatt 5760 ccgccgcctc ggtatgcaac gaacccttta agcccgtctc cagccctcga gggccgcgcg 5820 cagcataaaa gcggaggtta gcggcgggtg aggcggcgaa tgcctgagct tcaccaacga 5880 agcggctggc gagattggct tgttctgcgg cgcgatgctc ttcgcctaac gttttgccaa 5940 gcgttgttaa ctgttctgct gattgcgcca gtttcccgtt aagcaataac cagggtattt 6000 gtgtctgttc gctaacctgc cgtgcctggg agatccaggt ttcatccgta ttgccgcaat 6060 caacgaccaa atcgggatgt aacgccataa gcccttccag cgagagtgtg ctggcgcgcc 6120 cggcgagtcg tcccagcctg ggtaactggc gaatgtgctc tgacaatgga attaatgcct 6180 gacgggcaaa atcaaaagag gaaaaaccga ccattttttc tggcgcgaca gccagcaata 6240 gcaaatcggc gggcgcacct gcgctgacga tgcgtgtaat gttttgggct tcgggaagcg 6300 tcagtgaggc ccagaatttg actgattgtg caaaagaagg cagatgatgc aggaacaacg 6360 tcgacgcaag aatctgtgta aacctccgtc tggttagtga cataagttat atcctgataa 6420 ttaaaaccgc tatatattta catatatatc gaaaaaaatc atgtttgatg tcaaaatttg 6480 tctaaagaga cagaatgatt tgcttgttgc ttaaataaca ctttgttcca caagaaaatt 6540 gtcagggaga atggcggagt ggcgaaaaat ataaatagag gtgtactgat taacaaattg 6600 ataaaataaa ataaaattaa aatcttctct gatataagaa aataaaagca tagaccgtag 6660 aatggggggc atttcgtggc gaaaaaagag caatgccaat tttatgcaca taatggcatt 6720 gctcgatata cagcaaagtt aaggcgtagg ttccgcctct ttttgtttta ccggctgtgt 6780 tgttgattca ctgagt 6796 <210> 1419 <211> 285 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1973..2827) <400> 1419 <210> 1420 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2766..3047) <400> 1420 Met Pro Thr Leu Ile Leu Ser Val Asp Lys Ile Ala Asn Arg Ile Thr 1 5 10 15 Ala Pro Arg Asn Val Leu Ser Arg Thr Ser Ala Gly Val Leu Ala Arg 20 25 30 Leu Thr Thr Met Ser Val Ser Gly Tyr Ile Ala Gly Ile Asn Asn Lys 35 40 45 Met Leu Val Pro Ser Pro Leu Pro Ala Ala Thr Gly Arg Ser Ser Gly 50 55 60 Gly Ile Ala Tyr Arg Arg Arg His Cys Asp Asp Phe Pro Phe Ser Gly 65 70 75 80 Thr Asn Arg Cys Val Thr Ser Gly Arg Tyr Pro Gly Arg * 85 90 <210> 1421 <211> 215 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2992..3636) <400> 1421 Met Leu Ile Asp Asp Ile Asp Phe Ala Asp Leu Tyr Leu Gln Gln Leu 1 5 10 15 Lys Leu Ala His Arg Thr Glu Lys Thr Pro Asp His Trp Asp Gln Arg 20 25 30 Ala Glu Lys Met Ala Glu Asn Cys Ala Ser Pro Thr Asp Ser Tyr Leu 35 40 45 Gln Gln Leu Ile Ala Lys Ile Asp Leu Gln Gly Ala Gln Thr Leu Phe 50 55 60 Asp Met Gly Cys Gly Pro Gly Thr Val Ser Leu Ala Leu Ala Asp Lys 65 70 75 80 Leu Thr Thr Ile Tyr Gly Val Asp Tyr Ser Gln Gly Met Leu Asn Val 85 90 95 Ala Ala Arg Arg Ala Ala Ala Leu Lys Ala Asp Asn Val His Leu Ile 100 105 110 Gln Arg Ala Trp Glu Glu Asp Trp Ser Asp Leu Pro Arg Cys Asp Ile 115 120 125 Ala Val Ala Ser Arg Ser Thr Leu Val Ala Asp Met Arg Gln Ala Met 130 135 140 Ser Lys Leu Asn Asn Gln Ala Arg Leu Arg Val Tyr Thr Thr His Leu 145 150 155 160 Val Ser Thr Ser Phe Val Ser Pro Ala Ile Gln Arg Ala Ala Gly Arg 165 170 175 Glu Val Ile Glu Leu Pro Asn Tyr Ile Phe Ala Leu Asn Val Leu Tyr 180 185 190 Gln Met Gly Ile Tyr Ala His Val Asp Phe Ile Arg Gly Gln Asn Cys 195 200 205 Gln Gln Asp Asn Ser Thr * 210 <210> 1422 <211> 253 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3646..4404) <400> 1422 Val Thr Leu Leu Ala Val Arg His Ala Ser Leu Gly Tyr Ser Arg His 1 5 10 15 Pro Val Leu Arg Asp Val Ser Phe Thr Leu Ser Gln Gly Thr Ile Cys 20 25 30 Cys Leu Leu Gly Ala Asn Gly Cys Gly Lys Thr Thr Leu Met Arg Ser 35 40 45 Ile Leu Gly Val Ile Pro Leu Leu Lys Gly Glu Val Leu Leu Asp Ser 50 55 60 Leu Pro Val Gln Thr Leu Ser His Arg Gln Arg Ala Gln Ala Ile Ala 65 70 75 80 Trp Val Pro Gln Ala His Asp Gly Ile Phe Ala Phe Ser Val Leu Asp 85 90 95 Met Val Leu Met Gly Leu Ala Pro Thr Ile Gly Ala Phe Ser Val Pro 100 105 110 Gly Lys Gln Glu Arg Leu Lys Ala Thr Glu Gln Leu Glu Lys Leu Gly 115 120 125 Ile Leu His Leu Ala Ala Arg Arg Trp Asn Thr Leu Ser Gly Gly Glu 130 135 140 Arg Gln Leu Ala Leu Ile Ala Arg Ala Leu Val Gln Gln Pro Arg Leu 145 150 155 160 Leu Leu Leu Asp Glu Pro Ala Ser Ser Leu Asp Phe Gly His Gln Ile 165 170 175 Gln Leu Leu Asp Thr Leu Ala Gln Leu Lys Asn Asn Gly Met Thr Met 180 185 190 Leu Met Ser Thr His His Pro Leu His Ala Asn Ala Ile Ala Asp Ser 195 200 205 Ile Ile Gln Val Glu Pro Asp Gly Arg Val Thr Gln Gly Leu Pro Thr 210 215 220 Glu Gln Leu Thr Thr Asn Lys Leu Ala Ala Leu Tyr Arg Val Ser Ala 225 230 235 240 Asp Gln Ile His His His Leu Ser Ala Ile Ser His * 245 250 <210> 1423 <211> 327 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4401..5381) <400> 1423 Met Arg Ile Val Asn Gly Cys Ile Leu Leu Leu Ala Ala Ile Ser Ile 1 5 10 15 Thr Phe Ala Ala Val Ser Gly Ala Tyr His Leu Asp Met Gln Gln Leu 20 25 30 Leu Ala Leu Ile Leu Arg Gln Glu Asn Val Pro Val Gln Glu Gln Ile 35 40 45 Val Phe Trp Gln Ile Arg Val Pro Arg Ile Leu Ala Ala Leu Leu Leu 50 55 60 Gly Ala Ala Leu Ala Gly Ala Gly Thr Thr Tyr Gln Gly Met Leu Arg 65 70 75 80 Asn Pro Leu Val Ser Pro Asp Ile Leu Gly Val Ser Ala Gly Ala Gly 85 90 95 Leu Gly Ala Cys Thr Ala Ile Leu Trp Gly Leu Ser Ile Val Tyr Ile 100 105 110 Gln Leu Tyr Ala Phe Cys Gly Gly Leu Met Val Val Ala Gly Val Trp 115 120 125 Leu Ile Thr Arg Arg Val Thr Arg His Asp Pro Ile Leu Thr Leu Val 130 135 140 Leu Val Gly Ile Ala Leu Gly Thr Leu Cys Gly Ala Gly Ile Ser Leu 145 150 155 160 Ile Lys Thr Leu Ala Asp Pro Tyr Thr Gln Leu Pro Ser Ile Thr Phe 165 170 175 Trp Leu Leu Gly Gly Leu Ser Thr Val Thr Leu Arg Asp Leu Cys Tyr 180 185 190 Ala Ala Pro Ile Ile Leu Ile Gly Ser Leu Pro Leu Phe Phe Leu Arg 195 200 205 Trp Arg Met Asn Leu Leu Thr Leu Ser Asp Asp Glu Ala Arg Ser Leu 210 215 220 Gly Leu Asn Val Thr Arg Leu Arg Phe Val Leu Ile Val Cys Ala Thr 225 230 235 240 Leu Ile Thr Ala Ser Thr Val Ala Ile Ala Gly Ile Ile Gly Trp Val 245 250 255 Gly Leu Val Val Pro His Ile Ala Arg Leu Leu Thr Gly His Asn His 260 265 270 Gln Gln Leu Leu Pro Met Ala Met Cys Thr Gly Ala Ile Leu Leu Leu 275 280 285 Leu Thr Asp Thr Leu Ala Arg Ser Ile Gly Thr Thr Glu Ile Pro Leu 290 295 300 Gly Ile Leu Thr Ala Phe Val Gly Ala Pro Phe Phe Leu Leu Leu Leu 305 310 315 320 Leu Arg Gly Gly Arg Gln * 325 <210> 1424 <211> 341 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5381..6403) <400> 1424 Met Ser Leu Thr Arg Arg Arg Phe Thr Gln Ile Leu Ala Ser Thr Leu 1 5 10 15 Phe Leu His His Leu Pro Ser Phe Ala Gln Ser Val Lys Phe Trp Ala 20 25 30 Ser Leu Thr Leu Pro Glu Ala Gln Asn Ile Thr Arg Ile Val Ser Ala 35 40 45 Gly Ala Pro Ala Asp Leu Leu Leu Leu Ala Val Ala Pro Glu Lys Met 50 55 60 Val Gly Phe Ser Ser Phe Asp Phe Ala Arg Gln Ala Leu Ile Pro Leu 65 70 75 80 Ser Glu His Ile Arg Gln Leu Pro Arg Leu Gly Arg Leu Ala Gly Arg 85 90 95 Ala Ser Thr Leu Ser Leu Glu Gly Leu Met Ala Leu His Pro Asp Leu 100 105 110 Val Val Asp Cys Gly Asn Thr Asp Glu Thr Trp Ile Ser Gln Ala Arg 115 120 125 Gln Val Ser Glu Gln Thr Gln Ile Pro Trp Leu Leu Leu Asn Gly Lys 130 135 140 Leu Ala Gln Ser Ala Glu Gln Leu Thr Thr Leu Gly Lys Thr Leu Gly 145 150 155 160 Glu Glu His Arg Ala Ala Glu Gln Ala Asn Leu Ala Ser Arg Phe Val 165 170 175 Gly Glu Ala Gln Ala Phe Ala Ala Ser Pro Ala Ala Asn Leu Arg Phe 180 185 190 Tyr Ala Ala Arg Gly Pro Arg Gly Leu Glu Thr Gly Leu Lys Gly Ser 195 200 205 Leu His Thr Glu Ala Ala Glu Leu Leu Gly Leu His Asn Val Ala Gln 210 215 220 Ile Ala Asp Arg Gln Gly Leu Thr Gln Val Ser Met Glu Asn Leu Leu 225 230 235 240 Arg Trp Gln Pro Asp Ile Ile Leu Val Gln Glu Ala Val Thr Ala Asp 245 250 255 Phe Ile Arg Arg Asp Pro Leu Trp His Gly Val Lys Ala Val Ala Glu 260 265 270 Gln Arg Ile Leu Phe Leu Ser Gly Leu Pro Phe Gly Trp Leu Asp Ala 275 280 285 Pro Pro Gly Ile Asn Arg Leu Leu Gly Leu Arg Arg Leu His Ala Trp 290 295 300 Leu Asp Pro Ala Ile Asn Arg Gln Phe Lys Ser Asp Met Gln His Tyr 305 310 315 320 Ala Gln Leu Phe Trp His Cys Ser Leu Ser Asp Ala Asp Tyr Gln Lys 325 330 335 Leu Val Ala Thr * 340 <210> 1425 <211> 67 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6511..6711) <400> 1425 Met Cys Ile Lys Leu Ala Leu Leu Phe Phe Arg His Glu Met Pro Pro 1 5 10 15 Ile Leu Arg Ser Met Leu Leu Phe Ser Tyr Ile Arg Glu Asp Phe Asn 20 25 30 Phe Ile Leu Phe Tyr Gln Phe Val Asn Gln Tyr Thr Ser Ile Tyr Ile 35 40 45 Phe Arg His Ser Ala Ile Leu Pro Asp Asn Phe Leu Val Glu Gln Ser 50 55 60 Val Ile * 65 <210> 1426 <211> 6561 <212> DNA <213> Escherichia coli O157:H7 <400> 1426 cacctaccaa cgcgccgtta tttccttacg gcgcagtaaa cttctgacaa atatcgactc 60 acgtcacatt tttttgatca cgatttggtc cctcaaaatg tgagacgctt cgatcctctt 120 tttctcccgt tcacctacta tacgcttgaa gttgtccatg attgtccata gacaactgta 180 aatgttcagg tgcgcgccat gaaatcatta agtaagtcgt cacaaatacc gctctatcaa 240 caagtggtgg agtggataag agaaagtatt tataccggag atctggtgga agacgatcgc 300 attccttcgg aataccagat tatggatatg ctggacgtga gtcggggaac cgttaaaaaa 360 gcggtcgccc aactggtaaa agaaggcgtg ttaatacagg tccagggtaa gggaacattt 420 gtcaaaaaag agaacgtggc atatccgtta ggtgaaggat tattgtcatt cgcggaatcg 480 ctggaaagcc agaaaataca ttttaccact gaagttatta cgtcacggat tgaatcggct 540 aatcgttatg tggcagagaa attaagaata acgcccggtc aggatattct ttaccttgaa 600 cgcttacgct caattggtga tgaaaaagcg atgctgatag agaaccgtat caatattgag 660 ctatgccccg gtattgctga aatcgatttt aatcaacaca atttatttcc aacaatagaa 720 agtttgtcgc aaagaaaaat tcgttactcg gaaagtcgct atgccgcgcg attaattggt 780 aatgaacgtg gtcatttttt agatatcagt gaagacgcac ccgttttgca tctggagcag 840 ttagtctttt tctcccgagg attacccatt gagtttggca acgtctggtt aaaaggaaat 900 aaatattatc ttggcaccgt actgcaacgg cgggaagtga gttaagtaca cttttttaag 960 aggaataaaa tgcaaggcat acattttcag gaaaattata ttcaacgact tccggcaggg 1020 ttaagcgttg aacagatcat ccgccagtta gcgcaaccgt tggttgccgc cgagctggtc 1080 gtccctgatt ttgccgatca cgtactgaaa cgtgaggcga cgtacccaac ggggctgcct 1140 accgaaccac cgtgcgtcgc tattccgcac acggaccata aacatgtcag gcacaatgca 1200 attgccgtcg gcatcctgcc ggaaccggta gagtttgccg atatgggcgg cgatcctgac 1260 cccgtacctg tcagggtgat ttttttgctc gccttaagcg aaagcaataa acaattaaat 1320 gccctgggct ggattatgga aatgattcag gatacgccct ttatgcaagc cctgcttgcg 1380 atggaaacaa cagaaataca cacagtaatc ttaaacaaaa tgaaagaacg aggtgaaata 1440 tgagtcaaac cattttattt gtctgcgcca cgggtattgc cacatccacg gcggtaacag 1500 aaaaagtcat ggaatattgc aaagagcaag gtcttaacgt caattattcc caaaccaacg 1560 ttgcctcttt acctggaaat actgacggcg tagcactggt agtttcaaca actaaagtgc 1620 cttatgaact cgacgtcccg gtggtgaacg gcttgccgat tattaccggt attggcgaag 1680 aaaaagtact ggcgcaaatt gtttctatcc ttaaaaagta attaataata attaatttca 1740 acccactcca tcaggcgcta acgcgaggtg cgctctcgcc tgaaaaagag gtttattatg 1800 aacgatatcg cgcataccct ctataatatt gtgcaatata tattgggatt tggcccgacg 1860 gtaatgttgc cgttggtgtt atttattctt gctctctgtt ttaaagtaaa acccgctaaa 1920 gccttacgtt cgtcattaac agtcggcatt ggttttgtcg gtatttatgc cattttcgat 1980 attctgacca gcaatgtcgg gccagcggcc caggcgatgg ttgaacgcac cggaattaat 2040 ttaccggtgg tagatttagg ctggccgccg ctttccgcta ttacatgggg ttcgccaatt 2100 gccccgtttg ttattcccct gaccattctg attaacgtgg cgatgctggc gttaaataaa 2160 acccgtaccg ttgacgtaga tatgtggaac tactggcatt ttgcccttgc tggtacgttg 2220 gtttattaca gcaccggcag cctgttcttt ggtttgctgg cggcggcgat tgctgcggtg 2280 gtagtactta aactcgccga ctggtctgcg ccactggtac aaaaatactt tggactggaa 2340 gggatctcat tgccgacgct ctcttcggtg gtgttcttcc cggtcggtct gctggtcgac 2400 aaaatcatcg accatatccc tggcctcaat cgtattcata tcgacccgga aaccgtacag 2460 aaaaagtttg gcatcttcgg cgaaccgatg atggttggca ctattctggg cattctgctc 2520 ggcgtaattg ccggatacga tttcaaaaaa gtattgctgc ttggcatcag cattggcggt 2580 gtgatgttca tcctgccacg catggtacgc atcctgatgg aaggtttatt accgctgtct 2640 gaagctatta aaaagtatct caatgccaaa taccctgacc gtgacgatct ctatatcggc 2700 ctggatatcg ccgttgccgt aggtaatccg gcgattatct ccaccgccct gctgctaacg 2760 ccaatctcgg tctttatcgc gtttgtcctt ccgggtaatg aagtcctgcc gcttggcgac 2820 cttgccaacc tggcggtaat ggcgtcgatg attgctttag ccagccgtgg caatattttc 2880 cgcaccgttc tggcggcgat cccggtgatt attgccgacc tatggattgc taccaaaatc 2940 gcgccgttta ttaccggaat ggcgaaagac gttaacttca aatttgccga aggctccagc 3000 ggccaggttt ccagttttct tgatggcggt aacccgttcc gcttctggct gctggaaatc 3060 ttcaacggca atctcatcgc cattggtctg gtgccggtta tcgccctggt actgtatggc 3120 attttccgaa tgacgcggag cacggtttat gcctgataac agcgcagcta tcgttatcga 3180 tattggcacc accaattgca aagtcacctg cttttcctgc ctggacgcaa cgacgttggg 3240 cgcgcataaa ttcgtgacgg caaagcagat ctccccacag ggcgatgtcg atttcgatat 3300 cgacgccctc tggcaggagg tccgccaggc gatagcgcaa ctgaacgccg cttcgccgct 3360 gccagtcaga cggatcagca ttgccagttt tggcgaatca ggcgtgttcc ttgacgagca 3420 tggcgagatc ctgacgccaa tgctggcatg gtatgaccgt cgcggtgaag agtatctggc 3480 aacgcttagc gaggcagaca gtgcggcact ttatgacatc tgcggtctac cactacacag 3540 caattactct gccttcaaaa tgcgctggtt gctggaacat tacccgctgc gtaatcgccg 3600 cggcctgcgc tggctacatg cgccggaagt gctgctctgg cggctgactg gcgaacagca 3660 cacggatatc accttagcca gccgcacgct gtgtctggac gtgcgcaaag gcgaatggtc 3720 agcgaaagcg gcggcgttgt tacacgttcc ctgtacggca tttgcgccat tggtgcagcc 3780 aggcgagcac gccggatggg tcagcgagtc actttgcaag acgcttgggt tctcgcaacc 3840 ggtcagcgtg acgctggccg gacatgacca tatggtgggt gcgcgagcgt tgcagatgat 3900 gccaggcgat atccttaact cgacggggac cacggaaggc attctgcaac tggatacaca 3960 accgacgctg gatgaacagg ccaaacgtga caagctggca aacggctgtt actcacttgc 4020 caaccagttc accctgtttg cgtcgctgcc cgtgggcggt ttcgcgctgg agtggctgcg 4080 caacacgttc cggctaaccg atgaggagat cgccgcatca cttactcgcg gacatgctga 4140 ttatctggcg gggaattggt tgctcgatga cattcccgtc tttattccac atcttcgcgg 4200 ttcgggttcg ccctataaaa atcgccatac ccgtggatta ttttatgggc ttggcgatac 4260 gttaagtatc gacatgttaa ttgccagcgt atcactggga ttaaccatgg aatttgccaa 4320 ctgcttcgcc tgttttaacg tgcctggcac cagcgcgtta aaagtgatcg gtccggcaac 4380 ccataatcct ctttggctgc aattaaaggc ggatatttta cagcgtccgg ttgaagcaat 4440 tgcatttaac gaggcggttt ctgtcggagc attattaacc gccgcaccgg atattccacc 4500 gccgccagtc gctatagccc aacgtttgtt accgaatcgg gcgagatacc atcaattaca 4560 gcgttatcag cacaaatgga aaagctggta tcagttgaaa ttacaacaag aaggcgtgat 4620 gccattacat catcgagagg aacactatgt tgaataaaac cgtggaggtc agaaacagta 4680 ctggcctgca tgcacgtccg gcggcctgtc tggcgaaagc cgccaaaaaa tatagctgta 4740 aagtgacgct gcactatgag ggtaatgata ttaatgccac cagcatgatg aatattatgc 4800 gcgccggaat aaaaggcgga aaaacggtgg aaatacgctg cgacggtgat gatgaaaacg 4860 aggccataca gactctcacc gacttatttc gcgaccgctt cggtgaagct gaataattaa 4920 ctgatattaa aagatgaggt tttcaatatg ccattagtta atggacggat actgctcgac 4980 cgcattcagg aaaaacgggt attagcgggc gcatttaata ccaccaatct ggagacgaca 5040 atttcaattt taaacgctat tgagcgttcg ggattaccca acttcattca gattgcgcca 5100 accaatgcac aactctcggg atacgattac atttatgaaa tcgtgaaacg tcacgccgat 5160 aaaatggatg ttccggtcag tcttcatctg gatcacggga aaacccagga ggatgttaaa 5220 caggcggtgc gcgcgggctt tacctcggtc atgattgacg gtgccgcatt ctcttttgaa 5280 gagaatatcg ctttcaccca ggaagctgtc gatttctgta aatcctatgg cgtaccggtt 5340 gaagcggagc tgggggcgat tctcggcaaa gaagatgatc acgtcagcga agccgattgc 5400 aaaacggaac cggaaaaggt gaagaccttt gtcgagcgta ccggttgcga catgctggca 5460 gtttctattg gcaacgttca tggcctggac gatataccgc gtatcgatat ccccctgctg 5520 aagcgcattg ccgaagtctg tccggtgccg ttggttattc acggcggctc cggtatcgcc 5580 ccggagatat tacgcagctt tgttaattat cgcgtcgcta aagtaaatat cgccagcgat 5640 ctgcgcaaag cgtttatcac cgccgtcggc aaagcgtatg tgaataatca caacgaggcg 5700 aatctggcac gagtcatggc atcagcaaaa aacgccgtcg aggaagatgt gtatagcaaa 5760 atcctgatga tgaatgaggg gcatcggttg gttagaaagg catcttaaga gccacaaaaa 5820 tatagcggcg caacagaaat tgttgggccg ctataagtta taaatgattc aaacgctcat 5880 tcagtgtttc aataatatag gtattaacag agacttgttg ctgcgcagcc gcattattaa 5940 ggcgttcact cagcgattct ggatagcgta acgtaaaggt cttaatcttt tctgtacgcg 6000 catacggctc aatacccgca gctttacaat cctcaagata ctctcgcagg gaaagttccc 6060 cttctttttg cagcccctga atgctgtcag agacaaaatc acaataacct gacaagccca 6120 ggaatttgcc acgaaatgca ttcagttctg gcacgtaagt gataacagca ggttgcccgg 6180 caatctccat agagtttggc gtcttcagtt tgatcatggt tttaccccta tacttagtaa 6240 ccagtcacgc acgctttcta cagcgccttt atcggtatct ggcgacggat gaggccgatg 6300 gaaacacgca acgctcatat ttagtatgag cttacaacgc gaacctcttc cttccttaat 6360 ttctccgcct aatgctttaa ccagtgactc tatatcagac cacttgatcc cttgaggaac 6420 aggagtttta aatatttgat ccaatgtatt tttttgtttc ttccgtaaag cctgtacctt 6480 ggttctcatg gcatgtcctt atgacttcac tttatgacat caatagtatg acatcacagt 6540 atgaagtcaa gtttcccttc c ６５
６１ ＜２１０＞ １４２７ ＜２１１＞ ２５２ ＜２１２＞ ＰＲＴ <221> CDS <222> complement(190..945) <400> 1427 Val Arg Ala Met Lys Ser Leu Ser Lys Ser Ser Gln Ile Pro Leu Tyr 1 5 10 15 Gln Gln Val Val Glu Trp Ile Arg Glu Ser Ile Tyr Thr Gly Asp Leu 20 25 30 Val Glu Asp Asp Arg Ile Pro Ser Glu Tyr Gln Ile Met Asp Met Leu 35 40 45 Asp Val Ser Arg Gly Thr Val Lys Lys Ala Val Ala Gln Leu Val Lys 50 55 60 Glu Gly Val Leu Ile Gln Val Gln Gly Lys Gly Thr Phe Val Lys Lys 65 70 75 80 Glu Asn Val Ala Tyr Pro Leu Gly Glu Gly Leu Leu Ser Phe Ala Glu 85 90 95 Ser Leu Glu Ser Gln Lys Ile His Phe Thr Thr Glu Val Ile Thr Ser 100 105 110 Arg Ile Glu Ser Ala Asn Arg Tyr Val Ala Glu Lys Leu Arg Ile Thr 115 120 125 Pro Gly Gln Asp Ile Leu Tyr Leu Glu Arg Leu Arg Ser Ile Gly Asp 130 135 140 Glu Lys Ala Met Leu Ile Glu Asn Arg Ile Asn Ile Glu Leu Cys Pro 145 150 155 160 Gly Ile Ala Glu Ile Asp Phe Asn Gln His Asn Leu Phe Pro Thr Ile 165 170 175 Glu Ser Leu Ser Gln Arg Lys Ile Arg Tyr Ser Glu Ser Arg Tyr Ala 180 185 190 Ala Arg Leu Ile Gly Asn Glu Arg Gly His Phe Leu Asp Ile Ser Glu 195 200 205 Asp Ala Pro Val Leu His Leu Glu Gln Leu Val Phe Phe Ser Arg Gly 210 215 220 Leu Pro Ile Glu Phe Gly Asn Val Trp Leu Lys Gly Asn Lys Tyr Tyr 225 230 235 240 Leu Gly Thr Val Leu Gln Arg Arg Glu Val Ser * 245 250 <210> 1428 <211> 158 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(970..1443) <400> 1428 Met Gln Gly Ile His Phe Gln Glu Asn Tyr Ile Gln Arg Leu Pro Ala 1 5 10 15 Gly Leu Ser Val Glu Gln Ile Ile Arg Gln Leu Ala Gln Pro Leu Val 20 25 30 Ala Ala Glu Leu Val Val Pro Asp Phe Ala Asp His Val Leu Lys Arg 35 40 45 Glu Ala Thr Tyr Pro Thr Gly Leu Pro Thr Glu Pro Pro Cys Val Ala 50 55 60 Ile Pro His Thr Asp His Lys His Val Arg His Asn Ala Ile Ala Val 65 70 75 80 Gly Ile Leu Pro Glu Pro Val Glu Phe Ala Asp Met Gly Gly Asp Pro 85 90 95 Asp Pro Val Pro Val Arg Val Ile Phe Leu Leu Ala Leu Ser Glu Ser 100 105 110 Asn Lys Gln Leu Asn Ala Leu Gly Trp Ile Met Glu Met Ile Gln Asp 115 120 125 Thr Pro Phe Met Gln Ala Leu Leu Ala Met Glu Thr Thr Glu Ile His 130 135 140 Thr Val Ile Leu Asn Lys Met Lys Glu Arg Gly Glu Ile * 145 150 155 <210> 1429 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1440..1721) <400> 1429 Met Ser Gln Thr Ile Leu Phe Val Cys Ala Thr Gly Ile Ala Thr Ser 1 5 10 15 Thr Ala Val Thr Glu Lys Val Met Glu Tyr Cys Lys Glu Gln Gly Leu 20 25 30 Asn Val Asn Tyr Ser Gln Thr Asn Val Ala Ser Leu Pro Gly Asn Thr 35 40 45 Asp Gly Val Ala Leu Val Val Ser Thr Thr Lys Val Pro Tyr Glu Leu 50 55 60 Asp Val Pro Val Val Asn Gly Leu Pro Ile Ile Thr Gly Ile Gly Glu 65 70 75 80 Glu Lys Val Leu Ala Gln Ile Val Ser Ile Leu Lys Lys * 85 90 <210> 1430 <211> 453 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1798..3156) <400> 1430 Met Asn Asp Ile Ala His Thr Leu Tyr Asn Ile Val Gln Tyr Ile Leu 1 5 10 15 Gly Phe Gly Pro Thr Val Met Leu Pro Leu Val Leu Phe Ile Leu Ala 20 25 30 Leu Cys Phe Lys Val Lys Pro Ala Lys Ala Leu Arg Ser Ser Leu Thr 35 40 45 Val Gly Ile Gly Phe Val Gly Ile Tyr Ala Ile Phe Asp Ile Leu Thr 50 55 60 Ser Asn Val Gly Pro Ala Ala Gln Ala Met Val Glu Arg Thr Gly Ile 65 70 75 80 Asn Leu Pro Val Val Asp Leu Gly Trp Pro Pro Leu Ser Ala Ile Thr 85 90 95 Trp Gly Ser Pro Ile Ala Pro Phe Val Ile Pro Leu Thr Ile Leu Ile 100 105 110 Asn Val Ala Met Leu Ala Leu Asn Lys Thr Arg Thr Val Asp Val Asp 115 120 125 Met Trp Asn Tyr Trp His Phe Ala Leu Ala Gly Thr Leu Val Tyr Tyr 130 135 140 Ser Thr Gly Ser Leu Phe Phe Gly Leu Leu Ala Ala Ala Ile Ala Ala 145 150 155 160 Val Val Val Leu Lys Leu Ala Asp Trp Ser Ala Pro Leu Val Gln Lys 165 170 175 Tyr Phe Gly Leu Glu Gly Ile Ser Leu Pro Thr Leu Ser Ser Val Val 180 185 190 Phe Phe Pro Val Gly Leu Leu Val Asp Lys Ile Ile Asp His Ile Pro 195 200 205 Gly Leu Asn Arg Ile His Ile Asp Pro Glu Thr Val Gln Lys Lys Phe 210 215 220 Gly Ile Phe Gly Glu Pro Met Met Val Gly Thr Ile Leu Gly Ile Leu 225 230 235 240 Leu Gly Val Ile Ala Gly Tyr Asp Phe Lys Lys Val Leu Leu Leu Gly 245 250 255 Ile Ser Ile Gly Gly Val Met Phe Ile Leu Pro Arg Met Val Arg Ile 260 265 270 Leu Met Glu Gly Leu Leu Pro Leu Ser Glu Ala Ile Lys Lys Tyr Leu 275 280 285 Asn Ala Lys Tyr Pro Asp Arg Asp Asp Leu Tyr Ile Gly Leu Asp Ile 290 295 300 Ala Val Ala Val Gly Asn Pro Ala Ile Ile Ser Thr Ala Leu Leu Leu 305 310 315 320 Thr Pro Ile Ser Val Phe Ile Ala Phe Val Leu Pro Gly Asn Glu Val 325 330 335 Leu Pro Leu Gly Asp Leu Ala Asn Leu Ala Val Met Ala Ser Met Ile 340 345 350 Ala Leu Ala Ser Arg Gly Asn Ile Phe Arg Thr Val Leu Ala Ala Ile 355 360 365 Pro Val Ile Ile Ala Asp Leu Trp Ile Ala Thr Lys Ile Ala Pro Phe 370 375 380 Ile Thr Gly Met Ala Lys Asp Val Asn Phe Lys Phe Ala Glu Gly Ser 385 390 395 400 Ser Gly Gln Val Ser Ser Phe Leu Asp Gly Gly Asn Pro Phe Arg Phe 405 410 415 Trp Leu Leu Glu Ile Phe Asn Gly Asn Leu Ile Ala Ile Gly Leu Val 420 425 430 Pro Val Ile Ala Leu Val Leu Tyr Gly Ile Phe Arg Met Thr Arg Ser 435 440 445 Thr Val Tyr Ala * 450 <210> 1431 <211> 503 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3149..4657) <400> 1431 Met Pro Asp Asn Ser Ala Ala Ile Val Ile Asp Ile Gly Thr Thr Asn 1 5 10 15 Cys Lys Val Thr Cys Phe Ser Cys Leu Asp Ala Thr Thr Leu Gly Ala 20 25 30 His Lys Phe Val Thr Ala Lys Gln Ile Ser Pro Gln Gly Asp Val Asp 35 40 45 Phe Asp Ile Asp Ala Leu Trp Gln Glu Val Arg Gln Ala Ile Ala Gln 50 55 60 Leu Asn Ala Ala Ser Pro Leu Pro Val Arg Arg Ile Ser Ile Ala Ser 65 70 75 80 Phe Gly Glu Ser Gly Val Phe Leu Asp Glu His Gly Glu Ile Leu Thr 85 90 95 Pro Met Leu Ala Trp Tyr Asp Arg Arg Gly Glu Glu Tyr Leu Ala Thr 100 105 110 Leu Ser Glu Ala Asp Ser Ala Ala Leu Tyr Asp Ile Cys Gly Leu Pro 115 120 125 Leu His Ser Asn Tyr Ser Ala Phe Lys Met Arg Trp Leu Leu Glu His 130 135 140 Tyr Pro Leu Arg Asn Arg Arg Gly Leu Arg Trp Leu His Ala Pro Glu 145 150 155 160 Val Leu Leu Trp Arg Leu Thr Gly Glu Gln His Thr Asp Ile Thr Leu 165 170 175 Ala Ser Arg Thr Leu Cys Leu Asp Val Arg Lys Gly Glu Trp Ser Ala 180 185 190 Lys Ala Ala Ala Leu Leu His Val Pro Cys Thr Ala Phe Ala Pro Leu 195 200 205 Val Gln Pro Gly Glu His Ala Gly Trp Val Ser Glu Ser Leu Cys Lys 210 215 220 Thr Leu Gly Phe Ser Gln Pro Val Ser Val Thr Leu Ala Gly His Asp 225 230 235 240 His Met Val Gly Ala Arg Ala Leu Gln Met Met Pro Gly Asp Ile Leu 245 250 255 Asn Ser Thr Gly Thr Thr Glu Gly Ile Leu Gln Leu Asp Thr Gln Pro 260 265 270 Thr Leu Asp Glu Gln Ala Lys Arg Asp Lys Leu Ala Asn Gly Cys Tyr 275 280 285 Ser Leu Ala Asn Gln Phe Thr Leu Phe Ala Ser Leu Pro Val Gly Gly 290 295 300 Phe Ala Leu Glu Trp Leu Arg Asn Thr Phe Arg Leu Thr Asp Glu Glu 305 310 315 320 Ile Ala Ala Ser Leu Thr Arg Gly His Ala Asp Tyr Leu Ala Gly Asn 325 330 335 Trp Leu Leu Asp Asp Ile Pro Val Phe Ile Pro His Leu Arg Gly Ser 340 345 350 Gly Ser Pro Tyr Lys Asn Arg His Thr Arg Gly Leu Phe Tyr Gly Leu 355 360 365 Gly Asp Thr Leu Ser Ile Asp Met Leu Ile Ala Ser Val Ser Leu Gly 370 375 380 Leu Thr Met Glu Phe Ala Asn Cys Phe Ala Cys Phe Asn Val Pro Gly 385 390 395 400 Thr Ser Ala Leu Lys Val Ile Gly Pro Ala Thr His Asn Pro Leu Trp 405 410 415 Leu Gln Leu Lys Ala Asp Ile Leu Gln Arg Pro Val Glu Ala Ile Ala 420 425 430 Phe Asn Glu Ala Val Ser Val Gly Ala Leu Leu Thr Ala Ala Pro Asp 435 440 445 Ile Pro Pro Pro Pro Val Ala Ile Ala Gln Arg Leu Leu Pro Asn Arg 450 455 460 Ala Arg Tyr His Gln Leu Gln Arg Tyr Gln His Lys Trp Lys Ser Trp 465 470 475 480 Tyr Gln Leu Lys Leu Gln Gln Glu Gly Val Met Pro Leu His His Arg 485 490 495 Glu Glu His Tyr Val Glu * 500 <210> 1432 <211> 90 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4647..4916) <400> 1432 Met Leu Asn Lys Thr Val Glu Val Arg Asn Ser Thr Gly Leu His Ala 1 5 10 15 Arg Pro Ala Ala Cys Leu Ala Lys Ala Ala Lys Lys Tyr Ser Cys Lys 20 25 30 Val Thr Leu His Tyr Glu Gly Asn Asp Ile Asn Ala Thr Ser Met Met 35 40 45 Asn Ile Met Arg Ala Gly Ile Lys Gly Gly Lys Thr Val Glu Ile Arg 50 55 60 Cys Asp Gly Asp Asp Glu Asn Glu Ala Ile Gln Thr Leu Thr Asp Leu 65 70 75 80 Phe Arg Asp Arg Phe Gly Glu Ala Glu * 85 <210> 1433 <211> 287 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4948..5808) <400> 1433 Met Pro Leu Val Asn Gly Arg Ile Leu Leu Asp Arg Ile Gln Glu Lys 1 5 10 15 Arg Val Leu Ala Gly Ala Phe Asn Thr Thr Asn Leu Glu Thr Thr Ile 20 25 30 Ser Ile Leu Asn Ala Ile Glu Arg Ser Gly Leu Pro Asn Phe Ile Gln 35 40 45 Ile Ala Pro Thr Asn Ala Gln Leu Ser Gly Tyr Asp Tyr Ile Tyr Glu 50 55 60 Ile Val Lys Arg His Ala Asp Lys Met Asp Val Pro Val Ser Leu His 65 70 75 80 Leu Asp His Gly Lys Thr Gln Glu Asp Val Lys Gln Ala Val Arg Ala 85 90 95 Gly Phe Thr Ser Val Met Ile Asp Gly Ala Ala Phe Ser Phe Glu Glu 100 105 110 Asn Ile Ala Phe Thr Gln Glu Ala Val Asp Phe Cys Lys Ser Tyr Gly 115 120 125 Val Pro Val Glu Ala Glu Leu Gly Ala Ile Leu Gly Lys Glu Asp Asp 130 135 140 His Val Ser Glu Ala Asp Cys Lys Thr Glu Pro Glu Lys Val Lys Thr 145 150 155 160 Phe Val Glu Arg Thr Gly Cys Asp Met Leu Ala Val Ser Ile Gly Asn 165 170 175 Val His Gly Leu Asp Asp Ile Pro Arg Ile Asp Ile Pro Leu Leu Lys 180 185 190 Arg Ile Ala Glu Val Cys Pro Val Pro Leu Val Ile His Gly Gly Ser 195 200 205 Gly Ile Ala Pro Glu Ile Leu Arg Ser Phe Val Asn Tyr Arg Val Ala 210 215 220 Lys Val Asn Ile Ala Ser Asp Leu Arg Lys Ala Phe Ile Thr Ala Val 225 230 235 240 Gly Lys Ala Tyr Val Asn Asn His Asn Glu Ala Asn Leu Ala Arg Val 245 250 255 Met Ala Ser Ala Lys Asn Ala Val Glu Glu Asp Val Tyr Ser Lys Ile 260 265 270 Leu Met Met Asn Glu Gly His Arg Leu Val Arg Lys Ala Ser * 275 280 285 <210> 1434 <211> 120 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5858..6217) <400> 1434 Met Ile Lys Leu Lys Thr Pro Asn Ser Met Glu Ile Ala Gly Gln Pro 1 5 10 15 Ala Val Ile Thr Tyr Val Pro Glu Leu Asn Ala Phe Arg Gly Lys Phe 20 25 30 Leu Gly Leu Ser Gly Tyr Cys Asp Phe Val Ser Asp Ser Ile Gln Gly 35 40 45 Leu Gln Lys Glu Gly Glu Leu Ser Leu Arg Glu Tyr Leu Glu Asp Cys 50 55 60 Lys Ala Ala Gly Ile Glu Pro Tyr Ala Arg Thr Glu Lys Ile Lys Thr 65 70 75 80 Phe Thr Leu Arg Tyr Pro Glu Ser Leu Ser Glu Arg Leu Asn Asn Ala 85 90 95 Ala Ala Gln Gln Gln Val Ser Val Asn Thr Tyr Ile Ile Glu Thr Leu 100 105 110 Asn Glu Arg Leu Asn His Leu * 115 <210> 1435 <211> 92 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(6214..6489) <400> 1435 Met Arg Thr Lys Val Gln Ala Leu Arg Lys Lys Gln Lys Asn Thr Leu 1 5 10 15 Asp Gln Ile Phe Lys Thr Pro Val Pro Gln Gly Ile Lys Trp Ser Asp 20 25 30 Ile Glu Ser Leu Val Lys Ala Leu Gly Gly Glu Ile Lys Glu Gly Arg 35 40 45 Gly Ser Arg Cys Lys Leu Ile Leu Asn Met Ser Val Ala Cys Phe His 50 55 60 Arg Pro His Pro Ser Pro Asp Thr Asp Lys Gly Ala Val Glu Ser Val 65 70 75 80 Arg Asp Trp Leu Leu Ser Ile Gly Val Lys Pro * 85 90 <210> 1436 <211> 6505 <212> DNA <213> Escherichia coli O157:H7 <400> 1436 tttaccatac tggatttcat tcgtaccatc attggagagt tgaaagccta tttgacccgc 60 accgtcctca ctgttttcta actcattttt taatatgctg gttcctgact cctgtatcgt 120 cactggttca aagtaatatt caacgtcact gggttcaaaa actaattcac cttgctcgcc 180 ctggatgcag tcaaatctta tatgatgaaa ctgataattt tcattattga tacgagacag 240 tacaaatagt ccagtgtcga tggattgatc ttcaaaacca caggtcatta aatttacctg 300 taaaatagta tttaaattaa aattaaagcg gacgctatta caattagtat tattccctgt 360 acatgaactc acttcaattt cgaacaacaa aggaaaagga gttcctgaaa aatatctgcg 420 gtgttggaac tatctgatac agatgcgata gagtatggaa tggtgaaatt tatcgcagat 480 agcatttctt ctaaattata agatgacttc cctggaagcg ctattttttt taccgtcaga 540 ttcaaagggg aaattaataa tataatgacg acttccgact ttaaacctta aagcgttctg 600 tgttaaaaaa tgaactttaa tggcgttggt cgtctcttgc aagtctgcac actcaatgat 660 attcccagta ttttcaattt tttcggcggt gagattacct ttcatactca gtggtttgag 720 tatatatgtt ccacgttgtt ccccgacatt ggtcaatcca cagggagcac tttgcacaat 780 aaaagaatat agactcaatg tgattaataa aagccacttc atagtaaact ccttttactg 840 gcatatatat gttttgtttt catcgataac gtgttgaaaa gtaatagtac agaataaatt 900 ctgttcatca ttgagagcaa cttttatgcc agttggaatt tcatctacgc gaataaaaag 960 gcgactaccc tggccaacga ctccaatatt gttttcctgg agatccagta cgtcatagcc 1020 aaaagttaat ggcgaaccat cgggacgcag tgcctgtata taccagggct tacgttggtc 1080 agttgtaaac tgcacataag aaactgctcc acggtaaggc gcaataattt gacgattgcc 1140 ctgcaattct gtttcacttt cactgtttgc tgtatcaagt accagatggt tttcacgatg 1200 aggtatcatc aggtcgtaaa caacctggcc tttgctgttt gttcggttgt atttttgtcc 1260 attaatatgc gcgccttcta acccaggcgc atccagaatt gcaaatgtat cggatagctg 1320 gttagtgata ttaataccac cgggccagac aactaatcca ctactaatac ttccaccact 1380 ttgccaggcg tttttagaat ggctatagct gccatctatt gtggcgatgg gagttctcca 1440 gcttaaattc gtaccaagcg atgtatcatt attttgttgt tgctgattaa catatatacc 1500 ataatttaac tgatcatgtt caccggctat gccagtaatt ccagtattgt tggaggaata 1560 gccatctttg gaaaatgagg tcgaattcga taagttaatt tggtgacgtg ttttggcaat 1620 atcatccccc cagtagaaag gaatggagat aaacagatta aaacgctcct cttctttgtc 1680 gttttcatca taggattggc tggcagagaa agtataactg atgcgttgcc agctattgga 1740 ataactgaat tggtaatctt tagcatttcc acttcgcccc cagtaattcc gccaaagcgc 1800 acttaatgat acatttccca gattattgga taaaggttgc atgatattgg cagaaaggct 1860 attttttctg ccaatatcat aaaaatcgtc atagtcactc tgatgattta ttttatcatt 1920 ttcgtaaaga tggtcgctga atgtcctgta atcctgcgaa gcataacgcc aggcggccac 1980 gctaaatcga gtggccgttt gtactagata tttattatag gcgacctgat agctcgtacc 2040 ttcgtgtgtt atatcattat ttaacttact actcgatcgt gtagcgtcaa aagagatggc 2100 acccagcggt gtattccaac catttcccag agttatagca ttatagttat cggataaaat 2160 cgtaccgcca taaagtgtca aaagattgtt gaggccatat atataatttg cctcgagaaa 2220 gtcctcctga ttctttacac catatatctt actgcgtccg gcgataaaat cgaaatttga 2280 aataccaggt tgcagcatgt taggcacgga agagtagggc accaaaaagg aacgaacact 2340 gccatctgct tcctttatgc tgacatcgag atcagagccg ctgcccgaga gttgcaaatc 2400 tgcgatagta aatggtcccg ggggaacctc tttttggtaa atgatgtagc cattttgcga 2460 aaccgttatc aaggcattac tttgcgcaac accttgtact aaaggtgtaa agctctgcat 2520 agaatcaggt agcatttgca tatcgcgaaa taagcgtatt ccgctaaatc tcagagagtc 2580 gaatatgagt gaggatgtgt aattttctcc tatctgaact gtgcttaata tctgcgacca 2640 gccatgttcc aggtaaagag tattactttg ccatgtgcct ttcatatcat cgggtttgct 2700 atagctggca tcagagtgta actgccaact aaataaattt aatccactgt taaatcggcc 2760 ataactggct gtattactgt tattattgct gtcataagag cgatactgac ttaaattata 2820 ggaggtataa aaagcatcaa tgccgcgatc ccaactttcc gggggaacgt aacctctttc 2880 aagttcattg atatacgcct gtggtactgt taaatttagt cggtgttcac tgatatccca 2940 ctgatattgt ccaccatgaa ccgctttatc cagtaaaata caattatctt ctgtattgag 3000 gttaccggtc tttaccccca gtttggttag tagcacctta ggcagacatg gtttgactgg 3060 tgactctggg atcgtgatat cttgttttcc acgccactgg ttatttacat aaaaatcaag 3120 ttcgtagttt cctggaagcg gttgtttatt atcgaaatga tattcggaaa ctttttctcc 3180 tttcatgccg ccgatcataa agtgcgtatc aaaagtttct tcagcataac ccggaaaaga 3240 atacaaaaaa ataatagcag cgacccatcg tgtcgtcctt aacatgactt tttcctgtta 3300 tctcgcggcg attttactat ggatgttatt cccgtaatca tcaactaccg ttagttcata 3360 ttctgatgcg tggttatttt ttaatgtaat gtcgttatgc gaaaagggag gcagtaagat 3420 actttcatta ttaactttca cgttttgtgc tttgatagtt gtaaccgtta tccagttggc 3480 tgtttcgttg tttattgaga tggcgttatt tttctttttg atatttaatt gagaaaggct 3540 ttttttatct accggagcta ttccgcttgg acgccaaagt aactttatcc ggttttgcaa 3600 tgcaagttta attttgtttt tccctgcatt ttgtggattg tttggaggga tatccagaac 3660 atttagataa aataaacttt ctttattgtg aggcaaattg tttggcattt ttcttatttt 3720 aagttgttgg ccagaaccac ctgctacacg acttactggc ggtgtgagaa taaatgtgac 3780 ctgaattttt tctggcgcga tagtggtgtt cccatcatcg atccatgcct gaatcaaaga 3840 ggcattttta ctttgattca ttaactgtac gagaacttct ctgttttttt ccggataaat 3900 aatgcgcgta ccatagatga ccacaccggc atgaacaggt aaaataaaaa atgacatcag 3960 taatgctgtt attattctca cgtaatcact ccgtaaataa taccggtagc agagctaccg 4020 gcaaaaaacg ttaatctgca ctgattttaa tcgttacggt tgactctacg gagccttttg 4080 taacaggatt gccacttgtg cgggcatatt gtgcatttaa attgagaaaa tattgaccag 4140 agccattatc tttcagcggt gtttttaacc ctggtctcat tctggtcaaa gtcccatcat 4200 cgaggaaaat ggcaaagcca atgttctcag cagttccttt attcagcgta aagttattag 4260 catcaaactc tgatgctagt acttcgatac ttggggctgt atttccgtca cactgaattt 4320 ctaagtcatg agaggttgaa ccggttttta aagtatagat ttcattattg ataagttgat 4380 tcattgcact ggttacaaca tcttcgacaa cgatatctgt tgtcgaatca ccattaacaa 4440 agtaacacgt tgtatcaaca acttctcctc taatggttag tgttccttga tcgacatcct 4500 tggcgaaggt tgttgcgcta aacatcaacg ttgtcgcaac gaagggaata atatactttt 4560 tcataaatca tccttaatta actggtatgg aaggtcactc gttttcaaac ccgattatgt 4620 gatcaggttg ttattattta gattaatgtt taaatttttt aatttcttga tgtgaagttg 4680 atgaaagttt gaaaatttaa tattcttaat tattcccttc tttataagaa gagcaaggtg 4740 ccatcattag agtgacagag taggatgttt cagagcatgc ttcagattat tttttatttc 4800 tctgcagtta attaataatt atcacaggta atttcattct gaaattactt cttttttggg 4860 gtgttttaat cttgatgaga tatttttttc ataaggaaca tagactcgtt gatgctctga 4920 aggtattttc tcatttctgg ggatgttttg tcgtaatcgt gcataaactt tttcagttct 4980 ttatacacat cattatttag ctttacattg tcgcgaacta aagtttgtac caatggtatc 5040 aaaatttcga aacgggacgg tttgtcatca atacttgcca gggttttgaa tactcctgtg 5100 tatctgtaac ctaagtgctt attgacaagt tgagtggtcc atcggccagg cataatatct 5160 tcacagcgca aattttttat catggtatta gtgaacgatg ttccaaatat gttgcttttt 5220 ttaatgaaga ggttgtttat ttctccattt gaaaagatgg tgtttgataa gtcgctttca 5280 aaacatgata tattggataa tacacaacca aaataatacc catatgaaag gttgctcttt 5340 tctattgtta tatttgatag caacagttta tgtatattaa tattaagggc agtcaaatac 5400 tggatgtttt gctcgttaag ttcatgcatc tccagcgatt tattataggg taataaaagt 5460 ataaattcct ttacattatc tccgcagtaa gaaaagacaa catcaaattt atcggtgatc 5520 atgttttcat ttgagcagta agctgatttc tctattaacc gactgggcga gctttttaat 5580 aaagataatt tttcacatag ttgtgaatat gccgcattgc tagttttaaa attctgccat 5640 gttattttct ggttatcatc tgtcgatgag gcggggattt tattgcattg ctcattgtat 5700 agctcaggat aaatattctt ttttattaga tttctgattt ccttattaaa ataacttttt 5760 ttcttgacta ttgcactgta cttagcgttt tgtgacgtct cctgatgatc ataaaatgac 5820 tggagatttc tgcaggcctc ataaaatatt tcaggagtgt atagctctgg gtatatttcc 5880 tgattgaagt ttgcctttaa aaatttaata aatttttcat ggcattcttg atatatctta 5940 atctcttcag aaagacattc gcttgttctg tcatcaaaaa catccaatct aagtaatgtg 6000 atgcctttgt gtttaaaaaa agaaaattga actgtatgtt ctatgagttt acatctataa 6060 aaatgtgcat ctctcagatg agtatattga aaaaaatgat ggaggactgg agatggttta 6120 ggcaaatcct ggcttctgaa aaagtcatca aacaaaatta agaactctgt tttatactcg 6180 caaaacactt ttactaactc attttgtctt gttttattta ttattacatc atctactata 6240 tttgatttat aaagacaatg tggcgaagtt gagataccat ctgtcattat cagtccttga 6300 agttgatgaa tttttattaa tttaatttat gagtgaatgt gactactatc aaaaatcgct 6360 cattaatttt aagaagtaca atataaatag gtatttaacc tgtgttgatt gctgttaata 6420 atttacaagg tctaatgagg agatatttat gaatggttaa agtatatagg aatttaattc 6480 aaaaatagag tggtcttaag tttaa 6505 <210> 1437 <211> 39 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(369..485) <400> 1437 Met Leu Ser Ala Ile Asn Phe Thr Ile Pro Tyr Ser Ile Ala Ser Val 1 5 10 15 Ser Asp Ser Ser Asn Thr Ala Asp Ile Phe Gln Glu Leu Leu Phe Leu 20 25 30 Cys Cys Ser Lys Leu Lys * 35 <210> 1438 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(496..822) <400> 1438 Met Lys Trp Leu Leu Leu Ile Thr Leu Ser Leu Tyr Ser Phe Ile Val 1 5 10 15 Gln Ser Ala Pro Cys Gly Leu Thr Asn Val Gly Glu Gln Arg Gly Thr 20 25 30 Tyr Ile Leu Lys Pro Leu Ser Met Lys Gly Asn Leu Thr Ala Glu Lys 35 40 45 Ile Glu Asn Thr Gly Asn Ile Ile Glu Cys Ala Asp Leu Gln Glu Thr 50 55 60 Thr Asn Ala Ile Lys Val His Phe Leu Thr Gln Asn Ala Leu Arg Phe 65 70 75 80 Lys Val Gly Ser Arg His Tyr Ile Ile Asn Phe Pro Phe Glu Ser Asp 85 90 95 Gly Lys Lys Asn Ser Ala Ser Arg Glu Val Ile Leu * 100 105 <210> 1439 <211> 817 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(835..3285) <400> 1439 Met Leu Arg Thr Thr Arg Trp Val Ala Ala Ile Ile Phe Leu Tyr Ser 1 5 10 15 Phe Pro Gly Tyr Ala Glu Glu Thr Phe Asp Thr His Phe Met Ile Gly 20 25 30 Gly Met Lys Gly Glu Lys Val Ser Glu Tyr His Phe Asp Asn Lys Gln 35 40 45 Pro Leu Pro Gly Asn Tyr Glu Leu Asp Phe Tyr Val Asn Asn Gln Trp 50 55 60 Arg Gly Lys Gln Asp Ile Thr Ile Pro Glu Ser Pro Val Lys Pro Cys 65 70 75 80 Leu Pro Lys Val Leu Leu Thr Lys Leu Gly Val Lys Thr Gly Asn Leu 85 90 95 Asn Thr Glu Asp Asn Cys Ile Leu Leu Asp Lys Ala Val His Gly Gly 100 105 110 Gln Tyr Gln Trp Asp Ile Ser Glu His Arg Leu Asn Leu Thr Val Pro 115 120 125 Gln Ala Tyr Ile Asn Glu Leu Glu Arg Gly Tyr Val Pro Pro Glu Ser 130 135 140 Trp Asp Arg Gly Ile Asp Ala Phe Tyr Thr Ser Tyr Asn Leu Ser Gln 145 150 155 160 Tyr Arg Ser Tyr Asp Ser Asn Asn Asn Ser Asn Thr Ala Ser Tyr Gly 165 170 175 Arg Phe Asn Ser Gly Leu Asn Leu Phe Ser Trp Gln Leu His Ser Asp 180 185 190 Ala Ser Tyr Ser Lys Pro Asp Asp Met Lys Gly Thr Trp Gln Ser Asn 195 200 205 Thr Leu Tyr Leu Glu His Gly Trp Ser Gln Ile Leu Ser Thr Val Gln 210 215 220 Ile Gly Glu Asn Tyr Thr Ser Ser Leu Ile Phe Asp Ser Leu Arg Phe 225 230 235 240 Ser Gly Ile Arg Leu Phe Arg Asp Met Gln Met Leu Pro Asp Ser Met 245 250 255 Gln Ser Phe Thr Pro Leu Val Gln Gly Val Ala Gln Ser Asn Ala Leu 260 265 270 Ile Thr Val Ser Gln Asn Gly Tyr Ile Ile Tyr Gln Lys Glu Val Pro 275 280 285 Pro Gly Pro Phe Thr Ile Ala Asp Leu Gln Leu Ser Gly Ser Gly Ser 290 295 300 Asp Leu Asp Val Ser Ile Lys Glu Ala Asp Gly Ser Val Arg Ser Phe 305 310 315 320 Leu Val Pro Tyr Ser Ser Val Pro Asn Met Leu Gln Pro Gly Ile Ser 325 330 335 Asn Phe Asp Phe Ile Ala Gly Arg Ser Lys Ile Tyr Gly Val Lys Asn 340 345 350 Gln Glu Asp Phe Leu Glu Ala Asn Tyr Ile Tyr Gly Leu Asn Asn Leu 355 360 365 Leu Thr Leu Tyr Gly Gly Thr Ile Leu Ser Asp Asn Tyr Asn Ala Ile 370 375 380 Thr Leu Gly Asn Gly Trp Asn Thr Pro Leu Gly Ala Ile Ser Phe Asp 385 390 395 400 Ala Thr Arg Ser Ser Ser Lys Leu Asn Asn Asp Ile Thr His Glu Gly 405 410 415 Thr Ser Tyr Gln Val Ala Tyr Asn Lys Tyr Leu Val Gln Thr Ala Thr 420 425 430 Arg Phe Ser Val Ala Ala Trp Arg Tyr Ala Ser Gln Asp Tyr Arg Thr 435 440 445 Phe Ser Asp His Leu Tyr Glu Asn Asp Lys Ile Asn His Gln Ser Asp 450 455 460 Tyr Asp Asp Phe Tyr Asp Ile Gly Arg Lys Asn Ser Leu Ser Ala Asn 465 470 475 480 Ile Met Gln Pro Leu Ser Asn Asn Leu Gly Asn Val Ser Leu Ser Ala 485 490 495 Leu Trp Arg Asn Tyr Trp Gly Arg Ser Gly Asn Ala Lys Asp Tyr Gln 500 505 510 Phe Ser Tyr Ser Asn Ser Trp Gln Arg Ile Ser Tyr Thr Phe Ser Ala 515 520 525 Ser Gln Ser Tyr Asp Glu Asn Asp Lys Glu Glu Glu Arg Phe Asn Leu 530 535 540 Phe Ile Ser Ile Pro Phe Tyr Trp Gly Asp Asp Ile Ala Lys Thr Arg 545 550 555 560 His Gln Ile Asn Leu Ser Asn Ser Thr Ser Phe Ser Lys Asp Gly Tyr 565 570 575 Ser Ser Asn Asn Thr Gly Ile Thr Gly Ile Ala Gly Glu His Asp Gln 580 585 590 Leu Asn Tyr Gly Ile Tyr Val Asn Gln Gln Gln Gln Asn Asn Asp Thr 595 600 605 Ser Leu Gly Thr Asn Leu Ser Trp Arg Thr Pro Ile Ala Thr Ile Asp 610 615 620 Gly Ser Tyr Ser His Ser Lys Asn Ala Trp Gln Ser Gly Gly Ser Ile 625 630 635 640 Ser Ser Gly Leu Val Val Trp Pro Gly Gly Ile Asn Ile Thr Asn Gln 645 650 655 Leu Ser Asp Thr Phe Ala Ile Leu Asp Ala Pro Gly Leu Glu Gly Ala 660 665 670 His Ile Asn Gly Gln Lys Tyr Asn Arg Thr Asn Ser Lys Gly Gln Val 675 680 685 Val Tyr Asp Leu Met Ile Pro His Arg Glu Asn His Leu Val Leu Asp 690 695 700 Thr Ala Asn Ser Glu Ser Glu Thr Glu Leu Gln Gly Asn Arg Gln Ile 705 710 715 720 Ile Ala Pro Tyr Arg Gly Ala Val Ser Tyr Val Gln Phe Thr Thr Asp 725 730 735 Gln Arg Lys Pro Trp Tyr Ile Gln Ala Leu Arg Pro Asp Gly Ser Pro 740 745 750 Leu Thr Phe Gly Tyr Asp Val Leu Asp Leu Gln Glu Asn Asn Ile Gly 755 760 765 Val Val Gly Gln Gly Ser Arg Leu Phe Ile Arg Val Asp Glu Ile Pro 770 775 780 Thr Gly Ile Lys Val Ala Leu Asn Asp Glu Gln Asn Leu Phe Cys Thr 785 790 795 800 Ile Thr Phe Gln His Val Ile Asp Glu Asn Lys Thr Tyr Ile Cys Gln 805 810 815 * <210> 1440 <211> 228 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3298..3981) <400> 1440 Val Arg Ile Ile Thr Ala Leu Leu Met Ser Phe Phe Ile Leu Pro Val 1 5 10 15 His Ala Gly Val Val Ile Tyr Gly Thr Arg Ile Ile Tyr Pro Glu Lys 20 25 30 Asn Arg Glu Val Leu Val Gln Leu Met Asn Gln Ser Lys Asn Ala Ser 35 40 45 Leu Ile Gln Ala Trp Ile Asp Asp Gly Asn Thr Thr Ile Ala Pro Glu 50 55 60 Lys Ile Gln Val Thr Phe Ile Leu Thr Pro Pro Val Ser Arg Val Ala 65 70 75 80 Gly Gly Ser Gly Gln Gln Leu Lys Ile Arg Lys Met Pro Asn Asn Leu 85 90 95 Pro His Asn Lys Glu Ser Leu Phe Tyr Leu Asn Val Leu Asp Ile Pro 100 105 110 Pro Asn Asn Pro Gln Asn Ala Gly Lys Asn Lys Ile Lys Leu Ala Leu 115 120 125 Gln Asn Arg Ile Lys Leu Leu Trp Arg Pro Ser Gly Ile Ala Pro Val 130 135 140 Asp Lys Lys Ser Leu Ser Gln Leu Asn Ile Lys Lys Lys Asn Asn Ala 145 150 155 160 Ile Ser Ile Asn Asn Glu Thr Ala Asn Trp Ile Thr Val Thr Thr Ile 165 170 175 Lys Ala Gln Asn Val Lys Val Asn Asn Glu Ser Ile Leu Leu Pro Pro 180 185 190 Phe Ser His Asn Asp Ile Thr Leu Lys Asn Asn His Ala Ser Glu Tyr 195 200 205 Glu Leu Thr Val Val Asp Asp Tyr Gly Asn Asn Ile His Ser Lys Ile 210 215 220 Ala Ala Arg * 225 <210> 1441 <211> 178 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4031..4564) <400> 1441 Met Lys Lys Tyr Ile Ile Pro Phe Val Ala Thr Thr Leu Met Phe Ser 1 5 10 15 Ala Thr Thr Phe Ala Lys Asp Val Asp Gln Gly Thr Leu Thr Ile Arg 20 25 30 Gly Glu Val Val Asp Thr Thr Cys Tyr Phe Val Asn Gly Asp Ser Thr 35 40 45 Thr Asp Ile Val Val Glu Asp Val Val Thr Ser Ala Met Asn Gln Leu 50 55 60 Ile Asn Asn Glu Ile Tyr Thr Leu Lys Thr Gly Ser Thr Ser His Asp 65 70 75 80 Leu Glu Ile Gln Cys Asp Gly Asn Thr Ala Pro Ser Ile Glu Val Leu 85 90 95 Ala Ser Glu Phe Asp Ala Asn Asn Phe Thr Leu Asn Lys Gly Thr Ala 100 105 110 Glu Asn Ile Gly Phe Ala Ile Phe Leu Asp Asp Gly Thr Leu Thr Arg 115 120 125 Met Arg Pro Gly Leu Lys Thr Pro Leu Lys Asp Asn Gly Ser Gly Gln 130 135 140 Tyr Phe Leu Asn Leu Asn Ala Gln Tyr Ala Arg Thr Ser Gly Asn Pro 145 150 155 160 Val Thr Lys Gly Ser Val Glu Ser Thr Val Thr Ile Lys Ile Ser Ala 165 170 175 Asp * <210> 1442 <211> 474 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4866..6287) <400> 1442 Met Thr Asp Gly Ile Ser Thr Ser Pro His Cys Leu Tyr Lys Ser Asn 1 5 10 15 Ile Val Asp Asp Val Ile Ile Asn Lys Thr Arg Gln Asn Glu Leu Val 20 25 30 Lys Val Phe Cys Glu Tyr Lys Thr Glu Phe Leu Ile Leu Phe Asp Asp 35 40 45 Phe Phe Arg Ser Gln Asp Leu Pro Lys Pro Ser Pro Val Leu His His 50 55 60 Phe Phe Gln Tyr Thr His Leu Arg Asp Ala His Phe Tyr Arg Cys Lys 65 70 75 80 Leu Ile Glu His Thr Val Gln Phe Ser Phe Phe Lys His Lys Gly Ile 85 90 95 Thr Leu Leu Arg Leu Asp Val Phe Asp Asp Arg Thr Ser Glu Cys Leu 100 105 110 Ser Glu Glu Ile Lys Ile Tyr Gln Glu Cys His Glu Lys Phe Ile Lys 115 120 125 Phe Leu Lys Ala Asn Phe Asn Gln Glu Ile Tyr Pro Glu Leu Tyr Thr 130 135 140 Pro Glu Ile Phe Tyr Glu Ala Cys Arg Asn Leu Gln Ser Phe Tyr Asp 145 150 155 160 His Gln Glu Thr Ser Gln Asn Ala Lys Tyr Ser Ala Ile Val Lys Lys 165 170 175 Lys Ser Tyr Phe Asn Lys Glu Ile Arg Asn Leu Ile Lys Lys Asn Ile 180 185 190 Tyr Pro Glu Leu Tyr Asn Glu Gln Cys Asn Lys Ile Pro Ala Ser Ser 195 200 205 Thr Asp Asp Asn Gln Lys Ile Thr Trp Gln Asn Phe Lys Thr Ser Asn 210 215 220 Ala Ala Tyr Ser Gln Leu Cys Glu Lys Leu Ser Leu Leu Lys Ser Ser 225 230 235 240 Pro Ser Arg Leu Ile Glu Lys Ser Ala Tyr Cys Ser Asn Glu Asn Met 245 250 255 Ile Thr Asp Lys Phe Asp Val Val Phe Ser Tyr Cys Gly Asp Asn Val 260 265 270 Lys Glu Phe Ile Leu Leu Leu Pro Tyr Asn Lys Ser Leu Glu Met His 275 280 285 Glu Leu Asn Glu Gln Asn Ile Gln Tyr Leu Thr Ala Leu Asn Ile Asn 290 295 300 Ile His Lys Leu Leu Leu Ser Asn Ile Thr Ile Glu Lys Ser Asn Leu 305 310 315 320 Ser Tyr Gly Tyr Tyr Phe Gly Cys Val Leu Ser Asn Ile Ser Cys Phe 325 330 335 Glu Ser Asp Leu Ser Asn Thr Ile Phe Ser Asn Gly Glu Ile Asn Asn 340 345 350 Leu Phe Ile Lys Lys Ser Asn Ile Phe Gly Thr Ser Phe Thr Asn Thr 355 360 365 Met Ile Lys Asn Leu Arg Cys Glu Asp Ile Met Pro Gly Arg Trp Thr 370 375 380 Thr Gln Leu Val Asn Lys His Leu Gly Tyr Arg Tyr Thr Gly Val Phe 385 390 395 400 Lys Thr Leu Ala Ser Ile Asp Asp Lys Pro Ser Arg Phe Glu Ile Leu 405 410 415 Ile Pro Leu Val Gln Thr Leu Val Arg Asp Asn Val Lys Leu Asn Asn 420 425 430 Asp Val Tyr Lys Glu Leu Lys Lys Phe Met His Asp Tyr Asp Lys Thr 435 440 445 Ser Pro Glu Met Arg Lys Tyr Leu Gln Ser Ile Asn Glu Ser Met Phe 450 455 460 Leu Met Lys Lys Ile Ser His Gln Asp * 465 470 <210> 1443 <211> 6185 <212> DNA <213> Escherichia coli O157:H7 <400> 1443 cctgtgtttg cagacaaact gacttactga ttaattcggg caagattttt accctcaccc 60 taaccctctc ccgaaggggc gaggggaccg cccgtgcgcc tgattgggtg aagaagtgct 120 tagcgtggtt gcaaacagtt atcttctttc cagccgtaca accactccat gccgcgataa 180 aattctgcct gcgatttccc tttccacagc agattacgta cctggcgttc tacccctgcg 240 gcgtggtaaa cccgccccat ttcacgggtc gaccagacga tgcgcgcggt gcgcggaatt 300 cgtaccgact catacagcgc aaaggcttgc gccgcatcac cctcacactg cgccagcgcc 360 ttacccagcg ttactgcatc ttccagcgcc atacaggctc cctgcgccat atattgcgcc 420 accggatggg ccgaatcgcc cacaagcgtt atgcgcttcg ttccccactt cgccaccggt 480 tcacggtcag cggttgacca gcgtcgccat gaagtcggtt tatccaacat ctggcgcgga 540 cgggggtgaa tcccttcaaa gtaagagagc acttcctctt tactaccatc cttcacgccc 600 cactcttcct gctggcggct gtggaatgtt accaccaggt tatactgctt gccgccgcgc 660 aaagggtaat gcaccaagtg acaatgcggc cccgcccaca gtaccggtgc gttaatgcgc 720 aaatcttccg gcatatcggc acgatcgata accgcacggt agacaacatg tccggtgaca 780 cgcggcgcat cgcccaataa gctctggcgc accactgact tcacgccgtc acagccaatc 840 agaatatcgc cggtccagct attgccgcga tcgtcaaaca cggtgacatc gtcttccgtc 900 tcgcgaatat ccacgacgtt ggtggaggtg tgatattcca cgtccggatg cgtcagtacc 960 gcttcccaca ccgaggcgtg aatatcaacc cggtggatca ccgcgtaagg gccgccgaaa 1020 tggtcacgaa aggcctgccc ggtttcaatg cacaccactt cttcggcgtt caccgcatcc 1080 atcatggtaa tgtgatcggt aaacaccgcg cgctggcggg caacttcgcc gacgccgagg 1140 ctgtccagcg ccgaaaacgc atttggcccc aactggatgc ccgcgccaat ctcaccgatc 1200 tcatgcgcct tttccagcag caccactttg atccccaggc gggccagtga cagcgcagtt 1260 gccgcaccgc cgatcccgcc tcccacaatt actgcgcgtg tcactttcgt cattatagtt 1320 ctcctggtca ggctgaaatt ttatcttgtt gattttctgg cgctgcggca atgaacgctg 1380 gcagctgtgt gcaggcgtcg tacaccgctt tgcagcgtgg atacccgctc aaatcgcagt 1440 tcatgcgtag cgcgttcgcc cactgcggga caaggcagca atctgccagc gtcggcgtct 1500 cgcccacaca aaattgcccc gactggttct ggcgcaacag ttgttccacc gcgcttaacc 1560 cttgctggat ccagtgcgca taccaacgtt ttttttcttc ttcactgacg ttcagttctt 1620 cggtcaggta gcgcagcacg cgcaagttat tcaatggatg aatatcacaa gcgatggcat 1680 agacaatttc cagcaccttg ttgcgggccg gctcttcctg cggcaccagc ggaacttgcg 1740 ggtagtgcct ctccagccag tcaataatcg ccagcgattg tccgagtgat tcgccctcgt 1800 cagtcagcag cgtcggcacc agcccgaccg gattcatccg ccgataggcc agttcatttt 1860 gctgaccaat acggatattc accccttcgg tctggtaatt aatgcctttc agcgccagcg 1920 caatgcgtac ccggtacgac gctgaactat taaaaaaact gtacagcttc atcatgcacc 1980 tcagacaatc ttcaccgcga taggcgttaa gccctcgacg ttgcctgtga tcacatcacc 2040 tttcactacc gggccaaccc cttccggcgt accggtgaag atcagatcgc ccggttgcag 2100 ctcaaagaag cctgacagat agcagatggt ttcattcacc gaccagatga gatggcgaat 2160 atcgctgcgc tgatgatctt cgccgttaac ctgtaaccag attggcgcat tatcaatacc 2220 gccgatatcg cgggctttgt gcagcggcgc gatgggcgct gagagatcaa acgctttacc 2280 gatttcccac gggcggccca tctggcgcat ttccatttga cggtcacgcc gagtcatatc 2340 aagacccgtg gcataacccc agacatattc atgggcgtgt tccagcggga tatcgctgcc 2400 ttttttacca atcgccacca ccagttcaat ttcgtaatgg tagttatcgg tctgtgccgg 2460 atacggcagc gccagcgttt caccagcggc aaccggaaca acggcatccg ccggtttgca 2520 gaagaagaat ggcggttcac gatccggatc aaagcccatt tcgcgggcgt gagcggcata 2580 gttacgtccg acgcagtaaa cgcggcgcac ggggaattgt tcatcactgc caacaaccgg 2640 tacggtaacg ggcgcttgcg gttcgaatac gtattgagtc atttttctct cctaaattaa 2700 taacgcgctt cgcggaacag ccccagggct tcttgtaccg gtctgtccga aaaactaaat 2760 aaaacggaat cttgcgtggt ctggaacgac acgccatgcc aggtcggcac cacgaagata 2820 tcttttgcac taaagctgaa ggtttcattg ccgatgatga cctgcccgct accttccacc 2880 acatggtaga tggtgctgtc agtggtacgc gcaacgcgtg aggcaaaccc tttcggcagc 2940 agttgcagga aagcgcccat cgacggcatc ggatagccgc cggtgaccgg gttgacgtag 3000 cgcattttgt agccatccca ctcgtcggca tcgcccagtc gggttaaatc gtgcagcact 3060 tcgcggctgc ggtcataacg atagttaaag atcggcgagg agttccccgt ctgatgccgc 3120 agcggcaaca tattggcagc gtaacgcggc agataatctc cctctttacg cgttaccggt 3180 tgttgctctt ccggataatc ttcggcaaaa ccgcagccca gaatattcac taatggcaga 3240 tccagcccat cgagccagat aaccggttcg tcgccagggt taccgtgatc gtgccagcgc 3300 cactgcgggg tcaggataaa atcgccttca ttcattggcg tgcgttcgcc atcaacggcg 3360 gtaaatgccc ctttgccttc aacaataaaa cgcagcgccg actgattatg acgatgactc 3420 ggtgccactt cgcccggcat gatcagttgc aaaccggcat ataaagtcgc ggtaatggaa 3480 gactgcccgc gcagcgccgg gttttccagc accagcacgc ggcgcacggc ctctttcgca 3540 ccaatcaggc cgccgctctc cagtagcagc gggcggatct cctgataatt ccagtacgct 3600 ggcgcacagt tagcgttggg cgttttcggc accagatggt gcagtgactc ccacagcggg 3660 gtcaggtttt gcccggaaat atgctgataa aattgctcgc ggctattttg attgttatca 3720 gtcattgaga tgctccttat tcgttcacaa cgcctgcgcg aggcagtgag tcagggacag 3780 aggtcgactg gcgaaccacg gtaatcagca gggttaacat caccgcactg atcgccgcag 3840 gcacagcgat aatgaaaaac agggtgtcga aagagaaatt catcgccatc atcacgccgc 3900 cagacagcga accaacaatc gcgccgcagc ggccgatagc atttgaccag ctcacgcccg 3960 tggctcgact ttgtgttgga taaagtgttg cggtcagcgc attcagcccc acctgcgatc 4020 cgctaatgcc aatgccagtg ccgaaaatcg ccagcgccat caaccataat ccatcctggc 4080 ttaagccaat catcacgatg catatagcgc ctatggcata gctcagcgtc agcacgcgga 4140 aaggattgaa cttatccatc agcacaccca gcgccagcgc gcctaacgta ccaccaatct 4200 ggaacgcggc ggtgacccag gacgcgtgtt gcaggtcgat gccgcgatgg ttcagtagcg 4260 tcggcatcca gcttgagagc aggtaaataa tcagcaggct cataaagaac actacccaca 4320 gcatcaacgt gatgggtaac tgacgtccca taaacagttg acgaatgctg ccttttgtaa 4380 cggaggctga ttcaatgaga taaaagtggg tatcgacata acgctcgcgg gtgatggcgc 4440 tgacggtttt cgcaatcacc gcctgcggta gctggcggcg cacctgccag cgtggcgatt 4500 ccggcagaac taccagcagt gcgacaaaca gcatcagcgg taacacgccc cccaacacca 4560 gaatgccgtg ccagccaatc accggcacca gctgcgcact gacaatcccg ccaaacgccg 4620 aacccagcgt aaagccgcaa aacatcagcg tcaccagcgc gccgcggcgg cgggcaggca 4680 gatactccga ggtcatggtg atggtgttcg gcatcgcgcc gcccagaccc aggccggtga 4740 gaaagcgcag gaagaccagc gtttgcagat ccggtgagaa agccgaggcg aggcttaacg 4800 cgccaaacaa aaagacgcac agctcaatca cccgcttgcg accaaagcga tcggacaacg 4860 ggccacaaag cagtgcgcct gcggttaatc ctagcagacc cgcgccaaaa agcggggcga 4920 gatcgcctgc ggtgagttgc cagtgagtgc gaatatcagg ggcgataaat ccgatagccg 4980 cggtgtcaaa accatcgagc attaccacca gaaaacagca gatgataacg cgccactgca 5040 tcttgccgac cggagcagca tcgataagtg cttgtaaatc acgtcgttga gtcatagtaa 5100 atgcctcagt gcaggtaagg tagatgtttc ttttgttttg tatatgttgc gatattgtga 5160 ttaaagagat gagatgtaca atggcatttc gggcagagag ataaccttga ggttatggca 5220 aatggcgaac tgggcgcaaa aattaaaact acatcacctt gaaatgctgg tggcgctggg 5280 tgaacagggc aatctaaccc atgtcgcacg aatgatgaat atcacccaac ctgcgctttc 5340 gaaatggttg tcacaactcg aagatgagat tggaatcaca ctttttgagc ggcacagcaa 5400 aggattacgt ccgactgaag gcggcaaatt gttattgcaa catgcccaac ggttaatcaa 5460 tgacatggag cgatcgcaac atgaactggc ccgttttaaa caaggtggac tggtcggcag 5520 tctgaaaatt ggctgttctc ccgtcgccac tgactgcgta tcccaggcga ttttgcattt 5580 gcttacgaag atgccaactc tacacctgaa tatcgaagag aaggtgatga ccccattgct 5640 gcaagatcta ttggccggtt ctgtcgatgt ggtcgttggg cgaattggcg gtcgcgcatt 5700 gcagctgcca ctgaattatc aggtgctgta caccgagcca gtatgctttg tcgcccgccc 5760 tgagcaccca ctggcgaaat acgccaccct cagctggaat gatcttgcca actggcgctg 5820 gatcgtctgg ccgacgggta cccccattcg cattagtatt gataatgcgc tggtagacca 5880 cggcgtaatg ctgccagaaa acacgattga gtcggcgtcg atgaacgtca gtaccaacct 5940 gttacaaagc agcgatatga tctctatttt gtcattacgc ctggcgcaac gttatgccag 6000 ccagggacaa ctggtgatac tcaacctgcc aaagatagaa cagaaaggta gcgtcggtgt 6060 gttctggcgc aataacgaaa cgccttctta tgctttaagt cagtttctgc actttttaca 6120 gcagaattag tgtgctgaac ggggcgctcg cccgaggtta cctccctaaa attcaactat 6180 gctga 6185 <210> 1444 <211> 398 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(120..1313) <400> 1444 Met Thr Lys Val Thr Arg Ala Val Ile Val Gly Gly Gly Ile Gly Gly 1 5 10 15 Ala Ala Thr Ala Leu Ser Leu Ala Arg Leu Gly Ile Lys Val Val Leu 20 25 30 Leu Glu Lys Ala His Glu Ile Gly Glu Ile Gly Ala Gly Ile Gln Leu 35 40 45 Gly Pro Asn Ala Phe Ser Ala Leu Asp Ser Leu Gly Val Gly Glu Val 50 55 60 Ala Arg Gln Arg Ala Val Phe Thr Asp His Ile Thr Met Met Asp Ala 65 70 75 80 Val Asn Ala Glu Glu Val Val Cys Ile Glu Thr Gly Gln Ala Phe Arg 85 90 95 Asp His Phe Gly Gly Pro Tyr Ala Val Ile His Arg Val Asp Ile His 100 105 110 Ala Ser Val Trp Glu Ala Val Leu Thr His Pro Asp Val Glu Tyr His 115 120 125 Thr Ser Thr Asn Val Val Asp Ile Arg Glu Thr Glu Asp Asp Val Thr 130 135 140 Val Phe Asp Asp Arg Gly Asn Ser Trp Thr Gly Asp Ile Leu Ile Gly 145 150 155 160 Cys Asp Gly Val Lys Ser Val Val Arg Gln Ser Leu Leu Gly Asp Ala 165 170 175 Pro Arg Val Thr Gly His Val Val Tyr Arg Ala Val Ile Asp Arg Ala 180 185 190 Asp Met Pro Glu Asp Leu Arg Ile Asn Ala Pro Val Leu Trp Ala Gly 195 200 205 Pro His Cys His Leu Val His Tyr Pro Leu Arg Gly Gly Lys Gln Tyr 210 215 220 Asn Leu Val Val Thr Phe His Ser Arg Gln Gln Glu Glu Trp Gly Val 225 230 235 240 Lys Asp Gly Ser Lys Glu Glu Val Leu Ser Tyr Phe Glu Gly Ile His 245 250 255 Pro Arg Pro Arg Gln Met Leu Asp Lys Pro Thr Ser Trp Arg Arg Trp 260 265 270 Ser Thr Ala Asp Arg Glu Pro Val Ala Lys Trp Gly Thr Lys Arg Ile 275 280 285 Thr Leu Val Gly Asp Ser Ala His Pro Val Ala Gln Tyr Met Ala Gln 290 295 300 Gly Ala Cys Met Ala Leu Glu Asp Ala Val Thr Leu Gly Lys Ala Leu 305 310 315 320 Ala Gln Cys Glu Gly Asp Ala Ala Gln Ala Phe Ala Leu Tyr Glu Ser 325 330 335 Val Arg Ile Pro Arg Thr Ala Arg Ile Val Trp Ser Thr Arg Glu Met 340 345 350 Gly Arg Val Tyr His Ala Ala Gly Val Glu Arg Gln Val Arg Asn Leu 355 360 365 Leu Trp Lys Gly Lys Ser Gln Ala Glu Phe Tyr Arg Gly Met Glu Trp 370 375 380 Leu Tyr Gly Trp Lys Glu Asp Asn Cys Leu Gln Pro Arg * 385 390 395 <210> 1445 <211> 216 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1328..1975) <400> 1445 Met Met Lys Leu Tyr Ser Phe Phe Asn Ser Ser Ala Ser Tyr Arg Val 1 5 10 15 Arg Ile Ala Leu Ala Leu Lys Gly Ile Asn Tyr Gln Thr Glu Gly Val 20 25 30 Asn Ile Arg Ile Gly Gln Gln Asn Glu Leu Ala Tyr Arg Arg Met Asn 35 40 45 Pro Val Gly Leu Val Pro Thr Leu Leu Thr Asp Glu Gly Glu Ser Leu 50 55 60 Gly Gln Ser Leu Ala Ile Ile Asp Trp Leu Glu Arg His Tyr Pro Gln 65 70 75 80 Val Pro Leu Val Pro Gln Glu Glu Pro Ala Arg Asn Lys Val Leu Glu 85 90 95 Ile Val Tyr Ala Ile Ala Cys Asp Ile His Pro Leu Asn Asn Leu Arg 100 105 110 Val Leu Arg Tyr Leu Thr Glu Glu Leu Asn Val Ser Glu Glu Glu Lys 115 120 125 Lys Arg Trp Tyr Ala His Trp Ile Gln Gln Gly Leu Ser Ala Val Glu 130 135 140 Gln Leu Leu Arg Gln Asn Gln Ser Gly Gln Phe Cys Val Gly Glu Thr 145 150 155 160 Pro Thr Leu Ala Asp Cys Cys Leu Val Pro Gln Trp Ala Asn Ala Leu 165 170 175 Arg Met Asn Cys Asp Leu Ser Gly Tyr Pro Arg Cys Lys Ala Val Tyr 180 185 190 Asp Ala Cys Thr Gln Leu Pro Ala Phe Ile Ala Ala Ala Pro Glu Asn 195 200 205 Gln Gln Asp Lys Ile Ser Ala * 210 215 <210> 1446 <211> 234 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1981..2682) <400> 1446 Met Thr Gln Tyr Val Phe Glu Pro Gln Ala Pro Val Thr Val Pro Val 1 5 10 15 Val Gly Ser Asp Glu Gln Phe Pro Val Arg Arg Val Tyr Cys Val Gly 20 25 30 Arg Asn Tyr Ala Ala His Ala Arg Glu Met Gly Phe Asp Pro Asp Arg 35 40 45 Glu Pro Pro Phe Phe Phe Cys Lys Pro Ala Asp Ala Val Val Pro Val 50 55 60 Ala Ala Gly Glu Thr Leu Ala Leu Pro Tyr Pro Ala Gln Thr Asp Asn 65 70 75 80 Tyr His Tyr Glu Ile Glu Leu Val Val Ala Ile Gly Lys Lys Gly Ser 85 90 95 Asp Ile Pro Leu Glu His Ala His Glu Tyr Val Trp Gly Tyr Ala Thr 100 105 110 Gly Leu Asp Met Thr Arg Arg Asp Arg Gln Met Glu Met Arg Gln Met 115 120 125 Gly Arg Pro Trp Glu Ile Gly Lys Ala Phe Asp Leu Ser Ala Pro Ile 130 135 140 Ala Pro Leu His Lys Ala Arg Asp Ile Gly Gly Ile Asp Asn Ala Pro 145 150 155 160 Ile Trp Leu Gln Val Asn Gly Glu Asp His Gln Arg Ser Asp Ile Arg 165 170 175 His Leu Ile Trp Ser Val Asn Glu Thr Ile Cys Tyr Leu Ser Gly Phe 180 185 190 Phe Glu Leu Gln Pro Gly Asp Leu Ile Phe Thr Gly Thr Pro Glu Gly 195 200 205 Val Gly Pro Val Val Lys Gly Asp Val Ile Thr Gly Asn Val Glu Gly 210 215 220 Leu Thr Pro Ile Ala Val Lys Ile Val * 225 230 <210> 1447 <211> 343 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2697..3725) <400> 1447 Met Thr Asp Asn Asn Gln Asn Ser Arg Glu Gln Phe Tyr Gln His Ile 1 5 10 15 Ser Gly Gln Asn Leu Thr Pro Leu Trp Glu Ser Leu His His Leu Val 20 25 30 Pro Lys Thr Pro Asn Ala Asn Cys Ala Pro Ala Tyr Trp Asn Tyr Gln 35 40 45 Glu Ile Arg Pro Leu Leu Leu Glu Ser Gly Gly Leu Ile Gly Ala Lys 50 55 60 Glu Ala Val Arg Arg Val Leu Val Leu Glu Asn Pro Ala Leu Arg Gly 65 70 75 80 Gln Ser Ser Ile Thr Ala Thr Leu Tyr Ala Gly Leu Gln Leu Ile Met 85 90 95 Pro Gly Glu Val Ala Pro Ser His Arg His Asn Gln Ser Ala Leu Arg 100 105 110 Phe Ile Val Glu Gly Lys Gly Ala Phe Thr Ala Val Asp Gly Glu Arg 115 120 125 Thr Pro Met Asn Glu Gly Asp Phe Ile Leu Thr Pro Gln Trp Arg Trp 130 135 140 His Asp His Gly Asn Pro Gly Asp Glu Pro Val Ile Trp Leu Asp Gly 145 150 155 160 Leu Asp Leu Pro Leu Val Asn Ile Leu Gly Cys Gly Phe Ala Glu Asp 165 170 175 Tyr Pro Glu Glu Gln Gln Pro Val Thr Arg Lys Glu Gly Asp Tyr Leu 180 185 190 Pro Arg Tyr Ala Ala Asn Met Leu Pro Leu Arg His Gln Thr Gly Asn 195 200 205 Ser Ser Pro Ile Phe Asn Tyr Arg Tyr Asp Arg Ser Arg Glu Val Leu 210 215 220 His Asp Leu Thr Arg Leu Gly Asp Ala Asp Glu Trp Asp Gly Tyr Lys 225 230 235 240 Met Arg Tyr Val Asn Pro Val Thr Gly Gly Tyr Pro Met Pro Ser Met 245 250 255 Gly Ala Phe Leu Gln Leu Leu Pro Lys Gly Phe Ala Ser Arg Val Ala 260 265 270 Arg Thr Thr Asp Ser Thr Ile Tyr His Val Val Glu Gly Ser Gly Gln 275 280 285 Val Ile Ile Gly Asn Glu Thr Phe Ser Phe Ser Ala Lys Asp Ile Phe 290 295 300 Val Val Pro Thr Trp His Gly Val Ser Phe Gln Thr Thr Gln Asp Ser 305 310 315 320 Val Leu Phe Ser Phe Ser Asp Arg Pro Val Gln Glu Ala Leu Gly Leu 325 330 335 Phe Arg Glu Ala Arg Tyr * 340 <210> 1448 <211> 453 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3737..5095) <400> 1448 Met Thr Gln Arg Arg Asp Leu Gln Ala Leu Ile Asp Ala Ala Pro Val 1 5 10 15 Gly Lys Met Gln Trp Arg Val Ile Ile Cys Cys Phe Leu Val Val Met 20 25 30 Leu Asp Gly Phe Asp Thr Ala Ala Ile Gly Phe Ile Ala Pro Asp Ile 35 40 45 Arg Thr His Trp Gln Leu Thr Ala Gly Asp Leu Ala Pro Leu Phe Gly 50 55 60 Ala Gly Leu Leu Gly Leu Thr Ala Gly Ala Leu Leu Cys Gly Pro Leu 65 70 75 80 Ser Asp Arg Phe Gly Arg Lys Arg Val Ile Glu Leu Cys Val Phe Leu 85 90 95 Phe Gly Ala Leu Ser Leu Ala Ser Ala Phe Ser Pro Asp Leu Gln Thr 100 105 110 Leu Val Phe Leu Arg Phe Leu Thr Gly Leu Gly Leu Gly Gly Ala Met 115 120 125 Pro Asn Thr Ile Thr Met Thr Ser Glu Tyr Leu Pro Ala Arg Arg Arg 130 135 140 Gly Ala Leu Val Thr Leu Met Phe Cys Gly Phe Thr Leu Gly Ser Ala 145 150 155 160 Phe Gly Gly Ile Val Ser Ala Gln Leu Val Pro Val Ile Gly Trp His 165 170 175 Gly Ile Leu Val Leu Gly Gly Val Leu Pro Leu Met Leu Phe Val Ala 180 185 190 Leu Leu Val Val Leu Pro Glu Ser Pro Arg Trp Gln Val Arg Arg Gln 195 200 205 Leu Pro Gln Ala Val Ile Ala Lys Thr Val Ser Ala Ile Thr Arg Glu 210 215 220 Arg Tyr Val Asp Thr His Phe Tyr Leu Ile Glu Ser Ala Ser Val Thr 225 230 235 240 Lys Gly Ser Ile Arg Gln Leu Phe Met Gly Arg Gln Leu Pro Ile Thr 245 250 255 Leu Met Leu Trp Val Val Phe Phe Met Ser Leu Leu Ile Ile Tyr Leu 260 265 270 Leu Ser Ser Trp Met Pro Thr Leu Leu Asn His Arg Gly Ile Asp Leu 275 280 285 Gln His Ala Ser Trp Val Thr Ala Ala Phe Gln Ile Gly Gly Thr Leu 290 295 300 Gly Ala Leu Ala Leu Gly Val Leu Met Asp Lys Phe Asn Pro Phe Arg 305 310 315 320 Val Leu Thr Leu Ser Tyr Ala Ile Gly Ala Ile Cys Ile Val Met Ile 325 330 335 Gly Leu Ser Gln Asp Gly Leu Trp Leu Met Ala Leu Ala Ile Phe Gly 340 345 350 Thr Gly Ile Gly Ile Ser Gly Ser Gln Val Gly Leu Asn Ala Leu Thr 355 360 365 Ala Thr Leu Tyr Pro Thr Gln Ser Arg Ala Thr Gly Val Ser Trp Ser 370 375 380 Asn Ala Ile Gly Arg Cys Gly Ala Ile Val Gly Ser Leu Ser Gly Gly 385 390 395 400 Val Met Met Ala Met Asn Phe Ser Phe Asp Thr Leu Phe Phe Ile Ile 405 410 415 Ala Val Pro Ala Ala Ile Ser Ala Val Met Leu Thr Leu Leu Ile Thr 420 425 430 Val Val Arg Gln Ser Thr Ser Val Pro Asp Ser Leu Pro Arg Ala Gly 435 440 445 Val Val Asn Glu * 450 <210> 1449 <211> 319 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5174..6130) <400> 1449 Met Tyr Asn Gly Ile Ser Gly Arg Glu Ile Thr Leu Arg Leu Trp Gln 1 5 10 15 Met Ala Asn Trp Ala Gln Lys Leu Lys Leu His His Leu Glu Met Leu 20 25 30 Val Ala Leu Gly Glu Gln Gly Asn Leu Thr His Val Ala Arg Met Met 35 40 45 Asn Ile Thr Gln Pro Ala Leu Ser Lys Trp Leu Ser Gln Leu Glu Asp 50 55 60 Glu Ile Gly Ile Thr Leu Phe Glu Arg His Ser Lys Gly Leu Arg Pro 65 70 75 80 Thr Glu Gly Gly Lys Leu Leu Leu Gln His Ala Gln Arg Leu Ile Asn 85 90 95 Asp Met Glu Arg Ser Gln His Glu Leu Ala Arg Phe Lys Gln Gly Gly 100 105 110 Leu Val Gly Ser Leu Lys Ile Gly Cys Ser Pro Val Ala Thr Asp Cys 115 120 125 Val Ser Gln Ala Ile Leu His Leu Leu Thr Lys Met Pro Thr Leu His 130 135 140 Leu Asn Ile Glu Glu Lys Val Met Thr Pro Leu Leu Gln Asp Leu Leu 145 150 155 160 Ala Gly Ser Val Asp Val Val Val Gly Arg Ile Gly Gly Arg Ala Leu 165 170 175 Gln Leu Pro Leu Asn Tyr Gln Val Leu Tyr Thr Glu Pro Val Cys Phe 180 185 190 Val Ala Arg Pro Glu His Pro Leu Ala Lys Tyr Ala Thr Leu Ser Trp 195 200 205 Asn Asp Leu Ala Asn Trp Arg Trp Ile Val Trp Pro Thr Gly Thr Pro 210 215 220 Ile Arg Ile Ser Ile Asp Asn Ala Leu Val Asp His Gly Val Met Leu 225 230 235 240 Pro Glu Asn Thr Ile Glu Ser Ala Ser Met Asn Val Ser Thr Asn Leu 245 250 255 Leu Gln Ser Ser Asp Met Ile Ser Ile Leu Ser Leu Arg Leu Ala Gln 260 265 270 Arg Tyr Ala Ser Gln Gly Gln Leu Val Ile Leu Asn Leu Pro Lys Ile 275 280 285 Glu Gln Lys Gly Ser Val Gly Val Phe Trp Arg Asn Asn Glu Thr Pro 290 295 300 Ser Tyr Ala Leu Ser Gln Phe Leu His Phe Leu Gln Gln Asn * 305 310 315 <210> 1450 <211> 6133 <212> DNA <213> Escherichia coli O157:H7 <400> 1450 attcacaagt tcacgcggat gaacaggtgt gctgttggct gcgagatagg agggagaggc 60 aacgaccatt tcacgctgcc tgccggtaag gggcacagca atcatgtctt tttcaatgac 120 ctctccgagc cttacgccag catcgtaacc tgcggccacg atatcgaatt cctcatccgt 180 gacaacaata tcaagcgtaa cggctggatt ggctgctgca aacgaagcga ttagcggacc 240 tgaaagaaat tcttcagcta ttgacgtcac cgcgattctg agaagtccgc gtggcacatg 300 gtcagaaacc atctcttcga acgctgcctc aataccggat aaaggtaatg acagcgattt 360 atgcagccgt tctcccgctt ctgtcaaatt aactgagcgc gtggtccgca ttacaagcat 420 tgtcccgaat gcatcttcaa ggcgtcttat tccctgactg accgctgaac gggtaacgcc 480 cagccgtgcg gcggctttac taaaattact ctcttctgct accgcgataa aaatgggtaa 540 aagattaaga tcgattttca ttgtttaatg ccgctaacca ctgagtacat tgaaagcagg 600 atactggaac caatcataaa gttctattct ctctccgaac acatttgaag gagaacgtaa 660 tggataaggt catattaatt accggcgcat caagtggtat tggggaaggt attgccagag 720 agcttggaat gacaggtgca aaggttttac tgggagcacg cagagttgag cgtatcgaag 780 ccattgcaac cgaaatctgc cgcgcaggag gaattgctaa agcgcgggag ttggatgtca 840 cagaccgaca gtccatggcc gatttcgtgc aagcagcgct ggatagctgg gggcgagttg 900 atgttcttat caataatgcg ggcgttatgc cgctttcacc gcttgcagca ggaaaacaag 960 atgaatgggc gctcactatt gacgtgaata tcaaaggtgt actgtgggga attggcgctg 1020 tacttccggt gatggaagca cagggttccg gtcagataat caatcttggt tctattggtg 1080 ccctttctgt tgtgcccaca ggcgcagtct attgtgcatc aaaatttgca gtacgggcta 1140 tttctgatgg cttacggcag gaaagctcga aaatccgtgt gacctgcgta aatcctggcg 1200 ttgtcgaaag tgaactggct tcaaccatta cccatgtgga aaccatgaag gcaatggacg 1260 cctaccgttc tgttgcactt caacccgcgg atattgcccg tgctgtaagg catattattg 1320 aatctcccga aagcgttgat acaaccgaaa ttaccatcag acccactgca tctgcaaact 1380 gaagaataac ttttacattc acgttttatt aaataggtca gaaggaatat ttatatatcc 1440 ctgtgttttt catagcaaga tacattatgt attgctcacc ccgaaggaga tgaaggttta 1500 attacagaaa gattattttt cacaggaagt aaacatgact catgtttaat gtctttatat 1560 ataaaactca tcctctcaat tgtcagggaa attagcgtga atactatctg ttctttaatt 1620 gttgtggttg cactgtcttt attatcattc agtagcgtcg ccaaaacgat tactgccgtc 1680 ggttcaacca ttaacagcac tgaaaaagaa atttctttac aggcagaaaa acaagggaaa 1740 tcatataaaa ttctgggcgc gttttttaag aacagagttt atatgatagc aaagttaaca 1800 ccagtcagta aaaatgatgc ttcataaggc tcatggtata atttttaaga catgatcaag 1860 aagcacgtct attgactcaa aattgtcatt tgtcaggcaa tggaatacct gacaaatgac 1920 gctatcccaa tctattgtac cagtcgttct gctaattcta ccgatgcttc ggtctggagt 1980 ggtagagtaa tattggacac agttttattt tctctctttt tcgagggctg tatatcaaca 2040 ggaagaatac atccctaagc ggttaatgct ggagtaatca atagaccagc attaatcaca 2100 gatgattacc aatcagacag aaatggttaa atcgtcgaat tcatatttaa tacgttttct 2160 tacgccgctg aacagcttga aaaggatgca tattttaaat atcagtgaaa tgaacagttt 2220 attgccgtta ttaatagaaa tggagggata aatacgcgta ttctactgtt gcaacaaaaa 2280 caacggtatt gatcggtttt cataatgaag taacctgaca gatatgaaaa tgttgattga 2340 ggctaaatgc ccggattaag gttgtcgagg ggagccaggt ggttttttct tttggatgat 2400 ctccattgct ggatagtccc cttgtacaga taagtccgct ctttctcgct caaagcggcc 2460 cctggaattg aacgcagagt gactacctga cacaatattg cacagtgaag agtcggtcgt 2520 tgttaacgtt cagattttca atgtatcaat gaccatccgc agagcggggg agacgttgcg 2580 atgagggtaa tagagaaaca atccctccat tcgcaggctg taacgctgca acactctgat 2640 aagcttaccg tgttctaaat catccgcgac cagttcaaca ggaacatagg ccaacccgag 2700 gcccagccgg gcggcttctg cttccatata gctgtcggaa aaggcccatt gtccttcggg 2760 ttgatgagtg atttttttat catcctgatt gagttcccac tggtatacgc tgccgtcggc 2820 aaactgatag gcgatacagg gatgcgcctt taaatccgcc ggggtttgcg gaaaaccata 2880 gcgacgaaaa tgttccggag tccccacaat tgccatctcc atatcgggcg tgatgcgtac 2940 cgcgaccatg ccctggctga cttcaggccc caggcggaca cctgcatcga atctttcctc 3000 gatgatatcg acgaaccggc tctcatttat cagttcaagc tggatatcag gatatcgctg 3060 tttaaatacc gccagctttg gcagcaggca tttatcaatc gcgtgctggc tggcattgat 3120 acgcaccgtg ccggagggcg tctctcgata gtgcgccagc gtggcaagcc caagatctaa 3180 catttcaaat ccagatgccg tcttctggta gagctgctcg cctgcttgcg tcagcgacag 3240 tttacgcgtg gtgcgcacca gcagctggac gcccagcctt tcttcaagct cgcgaacaga 3300 acggctgact cctgactgag caagacccag ccgcttagcc gctgcggtaa agctgccttc 3360 ccgcaccacc tgcataaaca ggtatagctc gttgtagttc tccctttttg ccattgaaac 3420 attccccttc atgccggcaa tctcagcatt aatttataac aatatggtat taatcttagc 3480 attaatcgcc ccctaatcag cactaattct gctcactata atgaccccat caaagtaaag 3540 caccgcagcg ttgtccgtcg gaaacctgta tctctctgtt gttttttatg gggattttta 3600 tgaaagcctt cacccgaacg ctaaaaaccg cgatgccggt catgctgctt ttcgcatcat 3660 taagtggagt cacgacaatg agttatgctg attcaaccaa tcctaatgcc cctgtgtcca 3720 tgaccgataa atgggataaa acgttcgccg agagccagaa agtcgatcac cgtaaagtct 3780 cgttcccgaa ccgatatggc atcaccttag tgggcgatct ttacctgcct aaagaccgtg 3840 gcgatcgcaa gctggcggcg attgcggtca gtgggccatt tggcgcggtg aaagagcaat 3900 ccagcggctt gtatgcgcag acgctggcgg aacgagggtt tgttaccctg gcgttcgatc 3960 cttcttacac cggggaaagc ggcggctatc cgcgaaatgt cgcctcaccg gatatcaaca 4020 ctgaagattt cagcgcggcg gtggatttct tagggctgca aaaagaggta gatcgcaacc 4080 gtatcgggct gctcggtatt tgtggctggg gcggcatggc gctgaacgac gcggcgatgg 4140 atacccgcgt taaagcggtt gctaccagcg tgatgtatga catgagccgg gcgatgggcc 4200 atggtgtggg ggatggcgaa gaccgttatt ctaccgccga ccgtcgtgct gttctgcaat 4260 atttgaatga acagcgctgg aaggatgcgc agagcggaac gttcgctcac ggtggtcatg 4320 atattaatgt cgatagcaac ggcaaggtca gtgcgggcga gcgcattctg ccagaaacgc 4380 tgccggcaaa tcctcatccg gtactgaaag agttctttga ctactatcgc atgccgcgcg 4440 gcttccacga acgttccgtt aactctaccg gggcgtggac ggcaacgatg ccgctgtcat 4500 ttatgaatat gccgctgttg agctacgcca gtgaaatcac cattccgacg ctgattgtga 4560 ccggtgagaa agcacattca cgctattttg ctgaagatgc ttacaaggcg gttggcagta 4620 aagacaaaga gttggtggtg gtaccagggg caaatcacgt ggacctgtac gataacgtgg 4680 ccggaaaaat acctttcgcg aagttcgaac aatttttcca gaccaaactg aaataaaacc 4740 tcccctgaat tgatgcaaag ccaccggtct atggccggtg gcttttatcc tgatctttgt 4800 gaaatttcac tatgtcgaca ctaagccaaa caccatcacc tcatcatcag cacgcatact 4860 ggggcggtat ttttgccatg accctgtgcg tgtttgtgct gattgcttct gaatttatgc 4920 ccgtcagcct gctcacgccg attgcccgtg acctgggcgt gacggagggg ctggcagggc 4980 gggggattgc tatctccggt gcgctggcgg ttctgaccag cctgacgctt tcaacgctag 5040 ctggaaagat gaatcgtaag ttcctgctgc tggggatgac ggttctgatg gccgtatcgg 5100 ggcttattat tgcgctggct accagttatc tgatgtatat ggtcggtcgt gcgatgattg 5160 gtgtggccat tggcggattc tggtcgatgt cagcggcaac ggcgattcgt ctggtgccgc 5220 agcatcaggt cacgcgtgcg ctggcgattt tcaacgccgg taatgcgctg gcgacggtcg 5280 tggccgcgcc gctgggaagc tatctggggg ctacggtcgg atggcgaggc gctttcttgt 5340 gcttggtgcc catggcggtt gtcgccttta tctggcagtg cattagtctg cccagcatgg 5400 atgcgaataa aagccacacg tcatgtggcg cggtattccg cttatttagc cgccgcatgg 5460 ttgtggtcgg catgatagct tgtggcctgt ttttcatggg gcagtttgcg ctattcacct 5520 atgtgcgccc atttctggag tcggtgacac gggttaattc cttaggcttg tcgttgattt 5580 tgctgattat cggcgtggcc ggttttattg gcacgctggt tgtttcgata tttctcaaca 5640 gaaaatgcta ccccacgctg atggccatac ccggactgat ggccgtcatt gccatcggtc 5700 tgatgcttac cgggcatcac gtctggatgg tctcgctgct gttaggactc tggggcatgc 5760 tggccaccgc cgcgccaacc ggatggtgga catggattgc gcgtacgttg cctgacaacg 5820 ccgaagccgg aggcgggctc atggtcgcgg tgattcagct ctcaatcgcc cttggatcaa 5880 cggcaggagg catcgtgttt gaccgccttg gctggcagag tacgtttgcc atgagtagtg 5940 tgctgctcct ttgcgcgggc gtactgacct ttgttacagc acgccagaag gccggtgcgc 6000 tttagtccgg cgagggcgcg cgttgctgaa aaagttacac aaggcgatga gcaaccacta 6060 tgggtagggc gctcttttaa acgatttagg tgattttcta aaacggctac tgcaaatttt 6120 tctcttaatt tat 6133 <210> 1451 <211> 241 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(660..1382) <400> 1451 Met Asp Lys Val Ile Leu Ile Thr Gly Ala Ser Ser Gly Ile Gly Glu 1 5 10 15 Gly Ile Ala Arg Glu Leu Gly Met Thr Gly Ala Lys Val Leu Leu Gly 20 25 30 Ala Arg Arg Val Glu Arg Ile Glu Ala Ile Ala Thr Glu Ile Cys Arg 35 40 45 Ala Gly Gly Ile Ala Lys Ala Arg Glu Leu Asp Val Thr Asp Arg Gln 50 55 60 Ser Met Ala Asp Phe Val Gln Ala Ala Leu Asp Ser Trp Gly Arg Val 65 70 75 80 Asp Val Leu Ile Asn Asn Ala Gly Val Met Pro Leu Ser Pro Leu Ala 85 90 95 Ala Gly Lys Gln Asp Glu Trp Ala Leu Thr Ile Asp Val Asn Ile Lys 100 105 110 Gly Val Leu Trp Gly Ile Gly Ala Val Leu Pro Val Met Glu Ala Gln 115 120 125 Gly Ser Gly Gln Ile Ile Asn Leu Gly Ser Ile Gly Ala Leu Ser Val 130 135 140 Val Pro Thr Gly Ala Val Tyr Cys Ala Ser Lys Phe Ala Val Arg Ala 145 150 155 160 Ile Ser Asp Gly Leu Arg Gln Glu Ser Ser Lys Ile Arg Val Thr Cys 165 170 175 Val Asn Pro Gly Val Val Glu Ser Glu Leu Ala Ser Thr Ile Thr His 180 185 190 Val Glu Thr Met Lys Ala Met Asp Ala Tyr Arg Ser Val Ala Leu Gln 195 200 205 Pro Ala Asp Ile Ala Arg Ala Val Arg His Ile Ile Glu Ser Pro Glu 210 215 220 Ser Val Asp Thr Thr Glu Ile Thr Ile Arg Pro Thr Ala Ser Ala Asn 225 230 235 240 * <210> 1452 <211> 93 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1549..1827) <400> 1452 Met Ser Leu Tyr Ile Lys Leu Ile Leu Ser Ile Val Arg Glu Ile Ser 1 5 10 15 Val Asn Thr Ile Cys Ser Leu Ile Val Val Val Ala Leu Ser Leu Leu 20 25 30 Ser Phe Ser Ser Val Ala Lys Thr Ile Thr Ala Val Gly Ser Thr Ile 35 40 45 Asn Ser Thr Glu Lys Glu Ile Ser Leu Gln Ala Glu Lys Gln Gly Lys 50 55 60 Ser Tyr Lys Ile Leu Gly Ala Phe Phe Lys Asn Arg Val Tyr Met Ile 65 70 75 80 Ala Lys Leu Thr Pro Val Ser Lys Asn Asp Ala Ser * 85 90 <210> 1453 <211> 53 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1900..2058) <400> 1453 Met Glu Tyr Leu Thr Asn Asp Ala Ile Pro Ile Tyr Cys Thr Ser Arg 1 5 10 15 Ser Ala Asn Ser Thr Asp Ala Ser Val Trp Ser Gly Arg Val Ile Leu 20 25 30 Asp Thr Val Leu Phe Ser Leu Phe Phe Glu Gly Cys Ile Ser Thr Gly 35 40 45 Arg Ile His Pro * 50 <210> 1454 <211> 301 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2530..3432) <400> 1454 Met Lys Gly Asn Val Ser Met Ala Lys Arg Glu Asn Tyr Asn Glu Leu 1 5 10 15 Tyr Leu Phe Met Gln Val Val Arg Glu Gly Ser Phe Thr Ala Ala Ala 20 25 30 Lys Arg Leu Gly Leu Ala Gln Ser Gly Val Ser Arg Ser Val Arg Glu 35 40 45 Leu Glu Glu Arg Leu Gly Val Gln Leu Leu Val Arg Thr Thr Arg Lys 50 55 60 Leu Ser Leu Thr Gln Ala Gly Glu Gln Leu Tyr Gln Lys Thr Ala Ser 65 70 75 80 Gly Phe Glu Met Leu Asp Leu Gly Leu Ala Thr Leu Ala His Tyr Arg 85 90 95 Glu Thr Pro Ser Gly Thr Val Arg Ile Asn Ala Ser Gln His Ala Ile 100 105 110 Asp Lys Cys Leu Leu Pro Lys Leu Ala Val Phe Lys Gln Arg Tyr Pro 115 120 125 Asp Ile Gln Leu Glu Leu Ile Asn Glu Ser Arg Phe Val Asp Ile Ile 130 135 140 Glu Glu Arg Phe Asp Ala Gly Val Arg Leu Gly Pro Glu Val Ser Gln 145 150 155 160 Gly Met Val Ala Val Arg Ile Thr Pro Asp Met Glu Met Ala Ile Val 165 170 175 Gly Thr Pro Glu His Phe Arg Arg Tyr Gly Phe Pro Gln Thr Pro Ala 180 185 190 Asp Leu Lys Ala His Pro Cys Ile Ala Tyr Gln Phe Ala Asp Gly Ser 195 200 205 Val Tyr Gln Trp Glu Leu Asn Gln Asp Asp Lys Lys Ile Thr His Gln 210 215 220 Pro Glu Gly Gln Trp Ala Phe Ser Asp Ser Tyr Met Glu Ala Glu Ala 225 230 235 240 Ala Arg Leu Gly Leu Gly Leu Ala Tyr Val Pro Val Glu Leu Val Ala 245 250 255 Asp Asp Leu Glu His Gly Lys Leu Ile Arg Val Leu Gln Arg Tyr Ser 260 265 270 Leu Arg Met Glu Gly Leu Phe Leu Tyr Tyr Pro His Arg Asn Val Ser 275 280 285 Pro Ala Leu Arg Met Val Ile Asp Thr Leu Lys Ile * 290 295 300 <210> 1455 <211> 379 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3600..4736) <400> 1455 Met Lys Ala Phe Thr Arg Thr Leu Lys Thr Ala Met Pro Val Met Leu 1 5 10 15 Leu Phe Ala Ser Leu Ser Gly Val Thr Thr Met Ser Tyr Ala Asp Ser 20 25 30 Thr Asn Pro Asn Ala Pro Val Ser Met Thr Asp Lys Trp Asp Lys Thr 35 40 45 Phe Ala Glu Ser Gln Lys Val Asp His Arg Lys Val Ser Phe Pro Asn 50 55 60 Arg Tyr Gly Ile Thr Leu Val Gly Asp Leu Tyr Leu Pro Lys Asp Arg 65 70 75 80 Gly Asp Arg Lys Leu Ala Ala Ile Ala Val Ser Gly Pro Phe Gly Ala 85 90 95 Val Lys Glu Gln Ser Ser Gly Leu Tyr Ala Gln Thr Leu Ala Glu Arg 100 105 110 Gly Phe Val Thr Leu Ala Phe Asp Pro Ser Tyr Thr Gly Glu Ser Gly 115 120 125 Gly Tyr Pro Arg Asn Val Ala Ser Pro Asp Ile Asn Thr Glu Asp Phe 130 135 140 Ser Ala Ala Val Asp Phe Leu Gly Leu Gln Lys Glu Val Asp Arg Asn 145 150 155 160 Arg Ile Gly Leu Leu Gly Ile Cys Gly Trp Gly Gly Met Ala Leu Asn 165 170 175 Asp Ala Ala Met Asp Thr Arg Val Lys Ala Val Ala Thr Ser Val Met 180 185 190 Tyr Asp Met Ser Arg Ala Met Gly His Gly Val Gly Asp Gly Glu Asp 195 200 205 Arg Tyr Ser Thr Ala Asp Arg Arg Ala Val Leu Gln Tyr Leu Asn Glu 210 215 220 Gln Arg Trp Lys Asp Ala Gln Ser Gly Thr Phe Ala His Gly Gly His 225 230 235 240 Asp Ile Asn Val Asp Ser Asn Gly Lys Val Ser Ala Gly Glu Arg Ile 245 250 255 Leu Pro Glu Thr Leu Pro Ala Asn Pro His Pro Val Leu Lys Glu Phe 260 265 270 Phe Asp Tyr Tyr Arg Met Pro Arg Gly Phe His Glu Arg Ser Val Asn 275 280 285 Ser Thr Gly Ala Trp Thr Ala Thr Met Pro Leu Ser Phe Met Asn Met 290 295 300 Pro Leu Leu Ser Tyr Ala Ser Glu Ile Thr Ile Pro Thr Leu Ile Val 305 310 315 320 Thr Gly Glu Lys Ala His Ser Arg Tyr Phe Ala Glu Asp Ala Tyr Lys 325 330 335 Ala Val Gly Ser Lys Asp Lys Glu Leu Val Val Val Pro Gly Ala Asn 340 345 350 His Val Asp Leu Tyr Asp Asn Val Ala Gly Lys Ile Pro Phe Ala Lys 355 360 365 Phe Glu Gln Phe Phe Gln Thr Lys Leu Lys * 370 375 <210> 1456 <211> 398 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4812..6005) <400> 1456 Met Ser Thr Leu Ser Gln Thr Pro Ser Pro His His Gln His Ala Tyr 1 5 10 15 Trp Gly Gly Ile Phe Ala Met Thr Leu Cys Val Phe Val Leu Ile Ala 20 25 30 Ser Glu Phe Met Pro Val Ser Leu Leu Thr Pro Ile Ala Arg Asp Leu 35 40 45 Gly Val Thr Glu Gly Leu Ala Gly Arg Gly Ile Ala Ile Ser Gly Ala 50 55 60 Leu Ala Val Leu Thr Ser Leu Thr Leu Ser Thr Leu Ala Gly Lys Met 65 70 75 80 Asn Arg Lys Phe Leu Leu Leu Gly Met Thr Val Leu Met Ala Val Ser 85 90 95 Gly Leu Ile Ile Ala Leu Ala Thr Ser Tyr Leu Met Tyr Met Val Gly 100 105 110 Arg Ala Met Ile Gly Val Ala Ile Gly Gly Phe Trp Ser Met Ser Ala 115 120 125 Ala Thr Ala Ile Arg Leu Val Pro Gln His Gln Val Thr Arg Ala Leu 130 135 140 Ala Ile Phe Asn Ala Gly Asn Ala Leu Ala Thr Val Val Ala Ala Pro 145 150 155 160 Leu Gly Ser Tyr Leu Gly Ala Thr Val Gly Trp Arg Gly Ala Phe Leu 165 170 175 Cys Leu Val Pro Met Ala Val Val Ala Phe Ile Trp Gln Cys Ile Ser 180 185 190 Leu Pro Ser Met Asp Ala Asn Lys Ser His Thr Ser Cys Gly Ala Val 195 200 205 Phe Arg Leu Phe Ser Arg Arg Met Val Val Val Gly Met Ile Ala Cys 210 215 220 Gly Leu Phe Phe Met Gly Gln Phe Ala Leu Phe Thr Tyr Val Arg Pro 225 230 235 240 Phe Leu Glu Ser Val Thr Arg Val Asn Ser Leu Gly Leu Ser Leu Ile 245 250 255 Leu Leu Ile Ile Gly Val Ala Gly Phe Ile Gly Thr Leu Val Val Ser 260 265 270 Ile Phe Leu Asn Arg Lys Cys Tyr Pro Thr Leu Met Ala Ile Pro Gly 275 280 285 Leu Met Ala Val Ile Ala Ile Gly Leu Met Leu Thr Gly His His Val 290 295 300 Trp Met Val Ser Leu Leu Leu Gly Leu Trp Gly Met Leu Ala Thr Ala 305 310 315 320 Ala Pro Thr Gly Trp Trp Thr Trp Ile Ala Arg Thr Leu Pro Asp Asn 325 330 335 Ala Glu Ala Gly Gly Gly Leu Met Val Ala Val Ile Gln Leu Ser Ile 340 345 350 Ala Leu Gly Ser Thr Ala Gly Gly Ile Val Phe Asp Arg Leu Gly Trp 355 360 365 Gln Ser Thr Phe Ala Met Ser Ser Val Leu Leu Leu Cys Ala Gly Val 370 375 380 Leu Thr Phe Val Thr Ala Arg Gln Lys Ala Gly Ala Leu * 385 390 395 <210> 1457 <211> 6091 <212> DNA <213> Escherichia coli O157:H7 <400> 1457 cgcctcagac gactggttcg atcatatcaa cccgcatctg gcttgcctta gctggtcaat 60 gcggggactc tcctgtctac tcgcctaatt accaaacaat tcactccctt tacgtcgatt 120 taccgctggt tgatattctg aaaatgcatt tttaccgaaa tagccaccta taaacaataa 180 aaatatatag aagatatcat ttattaatta acaagcagtt acgtctcttt ttttcggatt 240 taattgtgaa attttaatca tcatattcat acaataaatt atctgtaaat tttttcccag 300 acatggtttc tttcatattt gacatttatt aataatcatc attagaatcc acgaaaataa 360 tatattcata caaacacaga catcttttga aacgaatgat acatttttat aatgaatgct 420 taaaacaata tttaatcgac acacatcact gtcattaatg taaagcaaca tagatcacca 480 ataatacaat ggacaactct accggcattg atcgctgggc ggaggaaata aggattttta 540 catgaactag aagaagattt ttttcagtgc tgtcactgtt tcagttctct gcgcattaac 600 gggatgtgac tacattgaag aaggcaagcc agaaagtagt ttattgaaac aacaagaaga 660 acataacaat aaaattgatc tacttgaaaa acaacaagca cagctaaaga gtcaactgga 720 aactattcaa aaacaacaaa ctggcataat aagcagtaca aagactttaa ctcacgtaat 780 taaatccgtt aaagatcaac aaaacacttt tatttttacc gagtttaacc cagcaaaaac 840 gaagtatttc atcctgaaca atggttcggt ggctttagcg ggtcgagtgt tatccattga 900 cgccacagag aatggcagtg ttattcatat ttcactggtc aacttattaa gtacacctat 960 ctcaaatatt ggttttaatg cgacatgggg tggtgaaaaa cctgtcgatg ccaaagagtt 1020 tgcccggtgg caacaattac ttttcaacac atcaatgaaa tccacattga aattattacc 1080 aggtcaatgg caagacatta atttgaccct gaagggtgta tcgcccaata acctgggata 1140 tctgaagtta gccatcaaca tggaaaatat tcagttcgac aatcttccct ctgctgaaaa 1200 tcggcagaaa agaagcaaaa aataaatgca gttagtacgc ttataacaag gaatagcgag 1260 catcattaat gaacaaaata tttaaagtta tctggaaccc tgcgacaggg aattatactg 1320 ttaccagcga aacggcaaaa agccgtggca agaaatctgg gcgcagtaag ctgttaattt 1380 ctgcgctggt tgcgggtgga atgttgtcgt cgtttggggc attggcgaat gccgggaatg 1440 acaacggtca gggtgttgat tacggtagtg gatcagctgg cgacggctgg gttgctatag 1500 gcaaaggggc gaaagcaaat acttttatga acaccagtgg ttccagtact gctgtgggtt 1560 atgacgctat agctgaaggc caatatagct ctgccatcgg gtcaaaaacc catgcgattg 1620 gtggtgcatc aatggccttt ggggttagtg caatatcaga aggcgataga agtatagcac 1680 tgggtgcctc ttcgtattca ttgggccaat actcaatggc cctcggccgt tattcaaaag 1740 cattgggtaa attgtctatt gctatggggg actcttccaa agcggaagga gcaaacgcca 1800 ttgccctggg aaatgccact aaagctactg agattatgag tattgctctt ggcgacaccg 1860 ccaatgcgtc aaaagcgtat tcaatggcgc tgggagcaag tagcgtcgca tctgaagaaa 1920 acgctattgc gataggtgct gagaccgaag ccgctgaaaa tgcaactgct attggcaata 1980 atgcgaaggc aaaagggact aatagcatgg caatggggtt cggaagcctt gccgataaag 2040 tcaatactat cgcattagga aatggcagcc aggctctggc agataatgca atcgccatag 2100 gccagggcaa caaagctgat ggcgtggatg ccatcgctct gggtaatggt agccagtcga 2160 gaggcttaaa caccattgcc ttaggcacag ccagtaatgc aactggtgat aagagtcttg 2220 cgcttggtag taatagcagt gccaacggta ttaactctgt cgcgctgggc gcagattcca 2280 ttgcggattt agacaatacc gtctctgtcg gcaatagttc attaaaacgc aagatcgtta 2340 atgtgaaaaa tggcgcgatc aagtctgaca gttacgatgc cattaatggt tcacagcttt 2400 atgccattag cgactcggta gcaaaaaggc ttggaggagg ggctgcagta gatgttgatg 2460 acggtactgt tacagcacca acctacaatt taaaaaatgg tagcaaaaat aacgtagggg 2520 ctgcgctcgc tgtacttgat gaaaacaccc tgcaatggga ccaaaccaaa ggcaaataca 2580 gcgctgctca tggtactagt agcccaactg ccagcgtaat caccgatgtt gcggatggca 2640 cgatttcagc ctccagtaag gatgcggtta acggttccca actgaaagct accaatgacg 2700 atgtcgaagc caacaccgcc aatatcgcta ctaataccag caacattgcc acgaatacgg 2760 caaatattgc caccaatacc accaatatca ccaacctgac ggattccgtt ggtgaccttc 2820 aggctgatgc cctgctctgg aacgaaacta aaaaggcatt cagtgcagct cacggccagg 2880 ataccaccag caaaatcacc aacgttaaag atgccgacct gacggctgac agcactgatg 2940 ctgttaacgg ctctcagctg aaaaccacca acgatgctgt ggcgacgaat accaccaata 3000 tcgccaataa cacttccaat attgccacta acaccaccaa catctctaac ctgactgaga 3060 cggtgactaa tcttggtgag gatgcgctga aatgggataa ggacaatggt gtattcacgg 3120 cagctcatgg caccgagacc accagcaaaa tcaccaacgt taaagatggc gacctgacga 3180 ctggcagcac cgatgccgtt aacggctctc agctgaaaac caccaacgat gccgtggcga 3240 cgaataccac caatatcgcc actaacacca ccaacatctc taatctgact gagacggtga 3300 ctaatcttgg tgaggatgcg ctgaaatggg ataaggacaa tggtgtcttc actgcagctc 3360 atggcaacaa taccgccagc aaaatcacca atatcctgga cggcacagtc actgcaacca 3420 gttccgatgc cattaacggt agccagcttt atgacttaag cagcaatatc gccacctact 3480 tcggcggcaa tgcttctgtg aatactgacg gtgtgtttac cggtccaacc tacaaaatcg 3540 gtgaaacaaa ttattataac gtcggcgatg cactggctgc gattaactcc tcatttagca 3600 cgtctctcgg cgatgctctg ctttgggatg ccaccgcagg taaattcagt gccaaacacg 3660 gtactaatgg tgacgcaagc gtgatcactg atgtcgcaga tggtgaaatt tcagactcca 3720 gttctgacgc agtaaacggc tcacaactcc acggcgtgag cagttatgtt gttgatgcgc 3780 tggggggtgg tgccgaagtc aatgcagacg gcaccatcac tgcgccgacg tacaccattg 3840 ctaatgctga ttacgataat gtcggtgatg ccctgaatgc tatcgatacc actcttgacg 3900 acgctctgct ctgggatgcg gacgccggtg aaaatggtgc atttagcgcc gctcacggaa 3960 aagataaaac tgccagtgta atcactaacg tcgctaacgg tgcaatctct gctgccagca 4020 gcgacgcgat taacggctca caactctata ccaccaataa gtacatcgct gatgcgctgg 4080 gtggtgacgc agaagtcaac gctgacggca ccatcaccgc accgacttac accattgcga 4140 acgccgagta caacaacgtc ggtgacgccc tggatgcgct tgatgataac gccctgctgt 4200 gggatgagac tgccaatggc ggtgctggag cctacaatgc cagccatgac ggtaaagcca 4260 gcatcatcac taatgtcgct aatggcagta ttagtgagga cagtaccgat gcagtgaacg 4320 gttctcagtt gaatgcgacg aatatgatga ttgagcagaa cacccaaatt atcaatcagc 4380 tcgctggtaa caccgacgca acctatatcc aagaaaacgg tgcgggtatt aactatgtgc 4440 gtactaacga cgacggctta gcgttcaacg acgccagcgc acagggtgtt ggcgctacag 4500 ctataggtta taactctgtc gccaaaggcg atagcagcgt agctattggt cagggcagct 4560 acagcgacgt tgatacgggt atcgccctgg gtagcagctc tgtttccagc cgagtgattg 4620 ccaaaggctc ccgtgacacc agcataacgg aaaatggcgt tgttattggt tacgacacca 4680 cggatggcga actgctcggt gcattgtcta tcggtgatga cggtaaatat cgtcaaatca 4740 tcaacgtagc cgatggttcc gaagcccatg acgccgttac ggttcgtcaa ttgcagaatg 4800 cgattggtgc ggtcgcaacc acgccgacta aatacttcca cgctaattca acggaagaag 4860 attcactggc agtgggaact gactcgctgg caatgggtgc gaaaaccatc gtgaatggcg 4920 ataaaggtat tggtatcggt tatggtgcct acgtggacgc gaatgcactt aacggcattg 4980 ccattggtag caatgcgcaa gtcattcatg tcaacagtat tgcgataggt aatggttcta 5040 cgaccactcg tggcgctcaa accaattata ccgcctacaa catggacgca ccgcagaact 5100 ctgtcggtga attctcagtc ggtagtgcgg atggtcaacg tcagatcact aacgtcgcag 5160 caggttcggc tgataccgat gcggtcaacg tgggtcagtt gaaagtaacg gatgcgcagg 5220 tttcccagaa tacccagagc attactaacc tggataatcg ggtaacgaat cttgattcac 5280 gcgtcaccaa tatcgaaaac ggtattggcg atatcgtcac caccggtagc accaagtact 5340 tcaagaccaa taccgatggt gtagatgcca gcgcgcaggg taaagatagc gtcgcgattg 5400 gttccggctc cattgctgcc gctgacaaca gcgtcgctct gggtacaggg tctgtggcaa 5460 ccgaagaaaa tacgatctct gtaggttcct ctactaacca acgtcgtatc accaacgtag 5520 ctgcaggtaa aaatgctacc gatgctgtta acgtggcaca gttgaagtct tccgaagctg 5580 gcggtgtacg ttacgacacc aaagctgatg gttctatcga ctatagcaat atcaccctcg 5640 gtggcggcaa cggcggtacg actcgtatca gcaacgtctc cgctggcgtc aacaacaacg 5700 acgtggtgaa ttacgcgcag ttgaagcaaa gcgtgcagga aacgaagcaa tacaccgatc 5760 agcgaatggt tgagatggat aacaaactgt ctaaaactga aagcaagttg agcggtggta 5820 tcgcttctgc aatggcaatg accggtctgc cgcaggctta cactccaggt gccagcatgg 5880 cctctattgg tggcggtact tacaacggtg aatcggcagt tgctttaggt gtatcgatgg 5940 tgagcgccaa tggtcgttgg gtctacaaat tacaaggtag taccaatagc cagggtgaat 6000 actccgccgc actcggtgcc ggtattcagt ggtaatgatc cattaagtta gtgtgactaa 6060 gggcaaacgc caaattgcct gatgcgttac g 6091 <210> 1458 <211> 194 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(644..1225) <400> 1458 Leu Lys Gln Gln Glu Glu His Asn Asn Lys Ile Asp Leu Leu Glu Lys 1 5 10 15 Gln Gln Ala Gln Leu Lys Ser Gln Leu Glu Thr Ile Gln Lys Gln Gln 20 25 30 Thr Gly Ile Ile Ser Ser Thr Lys Thr Leu Thr His Val Ile Lys Ser 35 40 45 Val Lys Asp Gln Gln Asn Thr Phe Ile Phe Thr Glu Phe Asn Pro Ala 50 55 60 Lys Thr Lys Tyr Phe Ile Leu Asn Asn Gly Ser Val Ala Leu Ala Gly 65 70 75 80 Arg Val Leu Ser Ile Asp Ala Thr Glu Asn Gly Ser Val Ile His Ile 85 90 95 Ser Leu Val Asn Leu Leu Ser Thr Pro Ile Ser Asn Ile Gly Phe Asn 100 105 110 Ala Thr Trp Gly Gly Glu Lys Pro Val Asp Ala Lys Glu Phe Ala Arg 115 120 125 Trp Gln Gln Leu Leu Phe Asn Thr Ser Met Lys Ser Thr Leu Lys Leu 130 135 140 Leu Pro Gly Gln Trp Gln Asp Ile Asn Leu Thr Leu Lys Gly Val Ser 145 150 155 160 Pro Asn Asn Leu Gly Tyr Leu Lys Leu Ala Ile Asn Met Glu Asn Ile 165 170 175 Gln Phe Asp Asn Leu Pro Ser Ala Glu Asn Arg Gln Lys Arg Ser Lys 180 185 190 Lys * <210> 1459 <211> 1589 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1269..6035) <400> 1459 Met Asn Lys Ile Phe Lys Val Ile Trp Asn Pro Ala Thr Gly Asn Tyr 1 5 10 15 Thr Val Thr Ser Glu Thr Ala Lys Ser Arg Gly Lys Lys Ser Gly Arg 20 25 30 Ser Lys Leu Leu Ile Ser Ala Leu Val Ala Gly Gly Met Leu Ser Ser 35 40 45 Phe Gly Ala Leu Ala Asn Ala Gly Asn Asp Asn Gly Gln Gly Val Asp 50 55 60 Tyr Gly Ser Gly Ser Ala Gly Asp Gly Trp Val Ala Ile Gly Lys Gly 65 70 75 80 Ala Lys Ala Asn Thr Phe Met Asn Thr Ser Gly Ser Ser Thr Ala Val 85 90 95 Gly Tyr Asp Ala Ile Ala Glu Gly Gln Tyr Ser Ser Ala Ile Gly Ser 100 105 110 Lys Thr His Ala Ile Gly Gly Ala Ser Met Ala Phe Gly Val Ser Ala 115 120 125 Ile Ser Glu Gly Asp Arg Ser Ile Ala Leu Gly Ala Ser Ser Tyr Ser 130 135 140 Leu Gly Gln Tyr Ser Met Ala Leu Gly Arg Tyr Ser Lys Ala Leu Gly 145 150 155 160 Lys Leu Ser Ile Ala Met Gly Asp Ser Ser Lys Ala Glu Gly Ala Asn 165 170 175 Ala Ile Ala Leu Gly Asn Ala Thr Lys Ala Thr Glu Ile Met Ser Ile 180 185 190 Ala Leu Gly Asp Thr Ala Asn Ala Ser Lys Ala Tyr Ser Met Ala Leu 195 200 205 Gly Ala Ser Ser Val Ala Ser Glu Glu Asn Ala Ile Ala Ile Gly Ala 210 215 220 Glu Thr Glu Ala Ala Glu Asn Ala Thr Ala Ile Gly Asn Asn Ala Lys 225 230 235 240 Ala Lys Gly Thr Asn Ser Met Ala Met Gly Phe Gly Ser Leu Ala Asp 245 250 255 Lys Val Asn Thr Ile Ala Leu Gly Asn Gly Ser Gln Ala Leu Ala Asp 260 265 270 Asn Ala Ile Ala Ile Gly Gln Gly Asn Lys Ala Asp Gly Val Asp Ala 275 280 285 Ile Ala Leu Gly Asn Gly Ser Gln Ser Arg Gly Leu Asn Thr Ile Ala 290 295 300 Leu Gly Thr Ala Ser Asn Ala Thr Gly Asp Lys Ser Leu Ala Leu Gly 305 310 315 320 Ser Asn Ser Ser Ala Asn Gly Ile Asn Ser Val Ala Leu Gly Ala Asp 325 330 335 Ser Ile Ala Asp Leu Asp Asn Thr Val Ser Val Gly Asn Ser Ser Leu 340 345 350 Lys Arg Lys Ile Val Asn Val Lys Asn Gly Ala Ile Lys Ser Asp Ser 355 360 365 Tyr Asp Ala Ile Asn Gly Ser Gln Leu Tyr Ala Ile Ser Asp Ser Val 370 375 380 Ala Lys Arg Leu Gly Gly Gly Ala Ala Val Asp Val Asp Asp Gly Thr 385 390 395 400 Val Thr Ala Pro Thr Tyr Asn Leu Lys Asn Gly Ser Lys Asn Asn Val 405 410 415 Gly Ala Ala Leu Ala Val Leu Asp Glu Asn Thr Leu Gln Trp Asp Gln 420 425 430 Thr Lys Gly Lys Tyr Ser Ala Ala His Gly Thr Ser Ser Pro Thr Ala 435 440 445 Ser Val Ile Thr Asp Val Ala Asp Gly Thr Ile Ser Ala Ser Ser Lys 450 455 460 Asp Ala Val Asn Gly Ser Gln Leu Lys Ala Thr Asn Asp Asp Val Glu 465 470 475 480 Ala Asn Thr Ala Asn Ile Ala Thr Asn Thr Ser Asn Ile Ala Thr Asn 485 490 495 Thr Ala Asn Ile Ala Thr Asn Thr Thr Asn Ile Thr Asn Leu Thr Asp 500 505 510 Ser Val Gly Asp Leu Gln Ala Asp Ala Leu Leu Trp Asn Glu Thr Lys 515 520 525 Lys Ala Phe Ser Ala Ala His Gly Gln Asp Thr Thr Ser Lys Ile Thr 530 535 540 Asn Val Lys Asp Ala Asp Leu Thr Ala Asp Ser Thr Asp Ala Val Asn 545 550 555 560 Gly Ser Gln Leu Lys Thr Thr Asn Asp Ala Val Ala Thr Asn Thr Thr 565 570 575 Asn Ile Ala Asn Asn Thr Ser Asn Ile Ala Thr Asn Thr Thr Asn Ile 580 585 590 Ser Asn Leu Thr Glu Thr Val Thr Asn Leu Gly Glu Asp Ala Leu Lys 595 600 605 Trp Asp Lys Asp Asn Gly Val Phe Thr Ala Ala His Gly Thr Glu Thr 610 615 620 Thr Ser Lys Ile Thr Asn Val Lys Asp Gly Asp Leu Thr Thr Gly Ser 625 630 635 640 Thr Asp Ala Val Asn Gly Ser Gln Leu Lys Thr Thr Asn Asp Ala Val 645 650 655 Ala Thr Asn Thr Thr Asn Ile Ala Thr Asn Thr Thr Asn Ile Ser Asn 660 665 670 Leu Thr Glu Thr Val Thr Asn Leu Gly Glu Asp Ala Leu Lys Trp Asp 675 680 685 Lys Asp Asn Gly Val Phe Thr Ala Ala His Gly Asn Asn Thr Ala Ser 690 695 700 Lys Ile Thr Asn Ile Leu Asp Gly Thr Val Thr Ala Thr Ser Ser Asp 705 710 715 720 Ala Ile Asn Gly Ser Gln Leu Tyr Asp Leu Ser Ser Asn Ile Ala Thr 725 730 735 Tyr Phe Gly Gly Asn Ala Ser Val Asn Thr Asp Gly Val Phe Thr Gly 740 745 750 Pro Thr Tyr Lys Ile Gly Glu Thr Asn Tyr Tyr Asn Val Gly Asp Ala 755 760 765 Leu Ala Ala Ile Asn Ser Ser Phe Ser Thr Ser Leu Gly Asp Ala Leu 770 775 780 Leu Trp Asp Ala Thr Ala Gly Lys Phe Ser Ala Lys His Gly Thr Asn 785 790 795 800 Gly Asp Ala Ser Val Ile Thr Asp Val Ala Asp Gly Glu Ile Ser Asp 805 810 815 Ser Ser Ser Asp Ala Val Asn Gly Ser Gln Leu His Gly Val Ser Ser 820 825 830 Tyr Val Val Asp Ala Leu Gly Gly Gly Ala Glu Val Asn Ala Asp Gly 835 840 845 Thr Ile Thr Ala Pro Thr Tyr Thr Ile Ala Asn Ala Asp Tyr Asp Asn 850 855 860 Val Gly Asp Ala Leu Asn Ala Ile Asp Thr Thr Leu Asp Asp Ala Leu 865 870 875 880 Leu Trp Asp Ala Asp Ala Gly Glu Asn Gly Ala Phe Ser Ala Ala His 885 890 895 Gly Lys Asp Lys Thr Ala Ser Val Ile Thr Asn Val Ala Asn Gly Ala 900 905 910 Ile Ser Ala Ala Ser Ser Asp Ala Ile Asn Gly Ser Gln Leu Tyr Thr 915 920 925 Thr Asn Lys Tyr Ile Ala Asp Ala Leu Gly Gly Asp Ala Glu Val Asn 930 935 940 Ala Asp Gly Thr Ile Thr Ala Pro Thr Tyr Thr Ile Ala Asn Ala Glu 945 950 955 960 Tyr Asn Asn Val Gly Asp Ala Leu Asp Ala Leu Asp Asp Asn Ala Leu 965 970 975 Leu Trp Asp Glu Thr Ala Asn Gly Gly Ala Gly Ala Tyr Asn Ala Ser 980 985 990 His Asp Gly Lys Ala Ser Ile Ile Thr Asn Val Ala Asn Gly Ser Ile 995 1000 1005 Ser Glu Asp Ser Thr Asp Ala Val Asn Gly Ser Gln Leu Asn Ala Thr 1010 1015 1020 Asn Met Met Ile Glu Gln Asn Thr Gln Ile Ile Asn Gln Leu Ala Gly 1025 1030 1035 1040 Asn Thr Asp Ala Thr Tyr Ile Gln Glu Asn Gly Ala Gly Ile Asn Tyr 1045 1050 1055 Val Arg Thr Asn Asp Asp Gly Leu Ala Phe Asn Asp Ala Ser Ala Gln 1060 1065 1070 Gly Val Gly Ala Thr Ala Ile Gly Tyr Asn Ser Val Ala Lys Gly Asp 1075 1080 1085 Ser Ser Val Ala Ile Gly Gln Gly Ser Tyr Ser Asp Val Asp Thr Gly 1090 1095 1100 Ile Ala Leu Gly Ser Ser Ser Val Ser Ser Arg Val Ile Ala Lys Gly 1105 1110 1115 1120 Ser Arg Asp Thr Ser Ile Thr Glu Asn Gly Val Val Ile Gly Tyr Asp 1125 1130 1135 Thr Thr Asp Gly Glu Leu Leu Gly Ala Leu Ser Ile Gly Asp Asp Gly 1140 1145 1150 Lys Tyr Arg Gln Ile Ile Asn Val Ala Asp Gly Ser Glu Ala His Asp 1155 1160 1165 Ala Val Thr Val Arg Gln Leu Gln Asn Ala Ile Gly Ala Val Ala Thr 1170 1175 1180 Thr Pro Thr Lys Tyr Phe His Ala Asn Ser Thr Glu Glu Asp Ser Leu 1185 1190 1195 1200 Ala Val Gly Thr Asp Ser Leu Ala Met Gly Ala Lys Thr Ile Val Asn 1205 1210 1215 Gly Asp Lys Gly Ile Gly Ile Gly Tyr Gly Ala Tyr Val Asp Ala Asn 1220 1225 1230 Ala Leu Asn Gly Ile Ala Ile Gly Ser Asn Ala Gln Val Ile His Val 1235 1240 1245 Asn Ser Ile Ala Ile Gly Asn Gly Ser Thr Thr Thr Arg Gly Ala Gln 1250 1255 1260 Thr Asn Tyr Thr Ala Tyr Asn Met Asp Ala Pro Gln Asn Ser Val Gly 1265 1270 1275 1280 Glu Phe Ser Val Gly Ser Ala Asp Gly Gln Arg Gln Ile Thr Asn Val 1285 1290 1295 Ala Ala Gly Ser Ala Asp Thr Asp Ala Val Asn Val Gly Gln Leu Lys 1300 1305 1310 Val Thr Asp Ala Gln Val Ser Gln Asn Thr Gln Ser Ile Thr Asn Leu 1315 1320 1325 Asp Asn Arg Val Thr Asn Leu Asp Ser Arg Val Thr Asn Ile Glu Asn 1330 1335 1340 Gly Ile Gly Asp Ile Val Thr Thr Gly Ser Thr Lys Tyr Phe Lys Thr 1345 1350 1355 1360 Asn Thr Asp Gly Val Asp Ala Ser Ala Gln Gly Lys Asp Ser Val Ala 1365 1370 1375 Ile Gly Ser Gly Ser Ile Ala Ala Ala Asp Asn Ser Val Ala Leu Gly 1380 1385 1390 Thr Gly Ser Val Ala Thr Glu Glu Asn Thr Ile Ser Val Gly Ser Ser 1395 1400 1405 Thr Asn Gln Arg Arg Ile Thr Asn Val Ala Ala Gly Lys Asn Ala Thr 1410 1415 1420 Asp Ala Val Asn Val Ala Gln Leu Lys Ser Ser Glu Ala Gly Gly Val 1425 1430 1435 1440 Arg Tyr Asp Thr Lys Ala Asp Gly Ser Ile Asp Tyr Ser Asn Ile Thr 1445 1450 1455 Leu Gly Gly Gly Asn Gly Gly Thr Thr Arg Ile Ser Asn Val Ser Ala 1460 1465 1470 Gly Val Asn Asn Asn Asp Val Val Asn Tyr Ala Gln Leu Lys Gln Ser 1475 1480 1485 Val Gln Glu Thr Lys Gln Tyr Thr Asp Gln Arg Met Val Glu Met Asp 1490 1495 1500 Asn Lys Leu Ser Lys Thr Glu Ser Lys Leu Ser Gly Gly Ile Ala Ser 1505 1510 1515 1520 Ala Met Ala Met Thr Gly Leu Pro Gln Ala Tyr Thr Pro Gly Ala Ser 1525 1530 1535 Met Ala Ser Ile Gly Gly Gly Thr Tyr Asn Gly Glu Ser Ala Val Ala 1540 1545 1550 Leu Gly Val Ser Met Val Ser Ala Asn Gly Arg Trp Val Tyr Lys Leu 1555 1560 1565 Gln Gly Ser Thr Asn Ser Gln Gly Glu Tyr Ser Ala Ala Leu Gly Ala 1570 1575 1580 Gly Ile Gln Trp * 1585 <210> 1460 <211> 5903 <212> DNA <213> Escherichia coli O157:H7 <400> 1460 ccggaataga ccattttaac ggattaacga ctattcagag ataggttggg ccaggatgct 60 ggcccagtaa cttactcata ggtgatggaa aaatttacaa gggcattcgc tgtgccacca 120 gtggcctgag tgttgacgac cacataactc gcctggtagt gaagcgacgt ggtttcgcca 180 tcaatcgccc attcaatcgg cgttccgctg gagcctttgg gaacttgctg cgttccttta 240 tcgtcctcta tcttcaacgc aacacccgtt gcgccaccag cctcaagggc aaacatggaa 300 tcatcatcgc tgtccgactg actgtccatc tcaacggtcg ctttggatat cccatcgcac 360 tctttgagtt caatggtgaa atctttcttg ctcaacaccg taccgactgc cgcaggtttt 420 tgcagcgtca ttgttcccat atcgacttcg agatcgcttt tttccatctc gcaagcttta 480 gtggtgatag tgatggagaa atgaatatcc cctgccgggc caagatccgt cgccgcattc 540 accccgcagg caaccagact caaactggcg atgccgctat gcagcaatcg tttgaacttc 600 atggcatcac tccatttcaa gatatatggt cgttacgcct tcaaacgtcc cgcctttagg 660 cgctttaccc gtcgtgctaa tcggtaaagc cagcagtcga atcgcggcat tgcggtgagt 720 tttagaatcc aggctgctca aatttaataa cgtggtgctg cttgaatcat tcggtaccaa 780 aattttgccg ctggaatctt tcaccagtac gccaatatcg gggttgccca tatccaccgc 840 tcggggatcg tcagcattgg ttgccccctc aaggcgcaac gcaaccttga taccatcaga 900 gatattgttg caatcgaagc tgaggttaat ttcttgctct gtcgcacctt caggcatttg 960 cccttgcctg tttttaaacg ccgaggaggg gaattcacca aatggcacat ccagcaccgt 1020 gccgggttta atttcgcaat cctgggttac ggtgacacgc ccctgaatag atacggaaga 1080 tatgggtatt gttccgtaat ctttatttgt tttcgaggca tacagttcgg caattaacgt 1140 cagagggatg acggaatcgc cgataaaggg tttagtaata gcaaaggaaa gtagacctgc 1200 gccgcccata tagggcgtag taatgacttt gttgcatccg gttgtttgca gcgcctgctg 1260 gtttttgaaa ggaacaaacc catacacact ggtactgatg cgaatgttcg tcgcaacctc 1320 cagttcctcc gtcaaagtat aatatttcat actgtcaacc gtacggccag aagggggaag 1380 catactcacc ccctgcacta gagtatcttt ttcattctta taagaatcag gacattcaca 1440 aattagcgat acgttttgtc cattagacca gttaaggaca tccggtaaaa ccgttcctgc 1500 gacgtttttt gccgcatcag gtataccaac atccacatcg acattatagt gataagtcgt 1560 gccatccgcg ggggtacatg gcccccacgc atctccggca aatgccttgc cagaaaatcc 1620 gaatacgcat cctaataagg ataatgctat tgccgctttc atttcgctct ccttgcttac 1680 tggcaattgg ccgaaacagg aataattccg ccctgtttta attccaggga taatttataa 1740 ggcgccacgc attgctgcga cgcgtcatta ccccatttaa tcaatacccg tccttcctct 1800 ggcattccgc taatatagag ctgtccttct tcaccaacga tactgctcac ctcgttttgt 1860 ttatcggtga ttagcgttgc cgttgctcca aagggcaccg ggctgcccgc ggaacgaagc 1920 agcgtcatta atacgcggta accaacgcgg gtatcaaaac gcgctctgac aatcgctcca 1980 cgcgttggca ccactttctg gaacgcattt tcaacgtcaa catcgtcacc caacgaatcg 2040 ctacgcagtg agatttcgtt ttcacgatac ggcatggcat aaggcacgat cgcgttaccc 2100 atccagtcaa cctgaacgcc gccgttattc accacgcggg cattgcgcgc accgggtacg 2160 gagatgagcg tcatggtttc gcctagcggt tgggaaagcg tcacgccttc gctatgaact 2220 atcacgccgc cgcgaacgct gtagttgagc tgccggtaat ctttcccgta gctatagcct 2280 acgttgacat taccggaccc accctgatag ccaacgttag cgttaccgct gttacccaca 2340 ccgttgctgg cgtagccttc ctggacactg tagctcaggt tgcgatcctc aagcagcgtt 2400 ccgctgaccc caacctgttg attggtacga ccatcctggt cggtcgtgac gcgatagtta 2460 ctccaggccc ggcctagtgg aacggaaata ttgaaagacc acaagcgatc gctttcatcc 2520 cattcagggc ttttattcca gctatatgca atactgtaac tgaccttgcc aatacgtccg 2580 ttgtaacccg ccgataccgt gttctgttta cctgcgtcgt tccagtaatc ctgctgcgtt 2640 aaatttaaat aaacagagcc ataggcccct aattgctgcg tcaggttacc ctgtatttcg 2700 ctgcgcttgt gataacggtt atagtcgctg tcagcgtcac tgcgcacatc ggtggcttcc 2760 tggaaggtat agaaaccgct ggtagagtac cgatagcccg caaggcggaa atcggtgccg 2820 ctttcgaagc tcttggaata taagaaacga taagattgtc cctggctatc gcgatcgtta 2880 ttcagttcgc ttttagcctg cgtcacatca atggaaatcg ccccgatata accaaagttt 2940 ttccctatcc ctaatgtaaa tgcattgtaa ttattagaga ttaatacgcc gccgtaggcc 3000 gtcatccccc acggtaaacc gtagatcaga tcaagctgcc cgaaacgcgg cgaggcgctg 3060 tcataattcc cggcctgata ttcacctgcg gcaaagctat atttgagatg gccttcacgc 3120 tggaaaattg gcaccgatga gaatggctaa ataaagcgtt gttcactgcc atccgcttct 3180 ttaataatga ccgtgagatc accgctgttt gcagtggggt aaagatcgtt tatttcaaag 3240 gcaccaggct gcacataggt gcgataaata acgtagccgt tttgttcaat actgacttcg 3300 gcgttgcttt tggcgatccc tcgaacgatg ggtgcaaagc ctcgctggct gtcgggcagc 3360 atctcttcat cagaggctaa catcgcgcca cgcatctgaa cgctgtcaaa aatgtccccc 3420 gcggtcgccg tatcccccat tgttaattgc gctttgaaag ggatgatggc cctactcaaa 3480 gacgtaccga tattatccca ctgcgctttg ccaccggaat ggctccaggt actgtaattc 3540 cgtaaccgcc aagcgccaag gttcagcccg ctgcgtaagt tgaggtagta gctgtcgctc 3600 tttagcgtat ctttaccatc atcatgatga acagtgccat tatcatcgac ataactgctg 3660 gaagaccccg tcgagtcata ttcactgttg ctcccgctaa aactgtaatc cagcagcaac 3720 gcagggatac cttcgtccca taaagattcc ggcaccgtgc cgcgcgccac ctggtgcatc 3780 gccgcctgag ggaaacttaa taccagcttt tgttcactga agtcgaaatg gcttgaggcc 3840 aggggaatga tttcgtcaaa cggtacgcag gcttcggcag acaccagatt gagggccgga 3900 aagctttcaa cgcgcacgcc catctctgcc agttgcgtcc ggctaaggca aggcacaagg 3960 gattccccca tcgctttgcg ctgtgcttct gtggcctctt taaattccag tgtgcgggtt 4020 tccattctct gttcattgac gtaaacagag acacgataga tgccgggtaa ctgctgttcc 4080 tggccttttt cgaacatcgt taaatcgaca tgctggccca caccctgaac gtcctccagg 4140 aatttggggt taaactttcc ggcatgtgca gaaaacgtgc tggcaacagc aaccgccacc 4200 acagagatag aaaaggaaga aaaagtacgt gaaacggtct tccgtgacat tgagctattt 4260 ctcctgaaaa gatattaatc aatcaacatt tttagtgatc atttccgctg acgatccaaa 4320 gtcattgatg gtgttatatt taattttaga aacgctacct accccggcgg gtaatgtgat 4380 atttaatgcc cctttagcgg gtaccatgcc tgctttttca atttctttgt cattcgcaaa 4440 aaattgatta aaggtaatat taaaaactgt cggattatca acgcggagct gattaccgtt 4500 acgcgtaaat cgcagttcat ttggcgcggt ttttacatca ccctttaaac ctgccgggcg 4560 ataaaaaagt ttgattcggg tgcgaacggc aatctgcaaa acatttttgt tttcgctgtc 4620 gtcactttta gatggaatgg ctttcacatt aacccagtag accgattcgc gatcctgagg 4680 caggccgggc gtaatattca caatacgcaa aatattgttc ttttctggat caagcttgaa 4740 tagtgggggc gtaataataa acggtgtttt tttgctgccc gcggcatcat ccacccagga 4800 ttggataaga aactcttccg tcttactttt attctgtacg gtcagcgagg cttctttctt 4860 actgccatca taaattacgc gagtagagct aagtccgacg ccacccgcca gaactgactg 4920 tgaaaggaac agagagagag ccaacgcaac aaatttactt ttcatcattc gatccatgaa 4980 ctttgacgac taatggcggc aattacgccg ccatttgtaa aacggacgat tactcgtaag 5040 acaggttgaa atcgacctgc gcattgccgt aaccggtcgt taccgttgcc agagtagaaa 5100 cgtagttagc ggtaaagtag agaaccgtct ggcctttact cagatcaaca cttgctttac 5160 caccgttaag agcgaccagg gtattgctgt tatcataaat accgatacca acacctttgg 5220 ccgcgcccgc ttcagtgcta acagaaatca gatcagattt atctgcatca ccaacaccac 5280 taaagctcac attggctttt ttcatcgtgg tggtatcgca atcttccagt ttgatttcga 5340 aaggttttgc cggggatttg tcaccaaccg cagcaaatac agatttttgt acctgaccca 5400 acacaacttc ctggttctga gagtcaacgg acagtacgca aggtgaatcc acgatctcgc 5460 ctgtaaattt aaccgtgccg tcaccagact ctgctgcgaa tacagtgcca gaagttaacg 5520 ccagtgcggt taaggcaaaa acgacctttt tcatgaaaaa ctccatttaa aaaattacat 5580 taaaaagaaa atcttgatgt attaaaatcg acaactttga aggaaggatt atacaatgaa 5640 atacgaataa taaaattata cgaataatat attaatagcg catccaattt caaatcttaa 5700 aaaaatcatt gcattacatt ttcacataaa aagctatcgt ttatttttag gaataaataa 5760 atataaaata ccaattaaac aaaacaaaaa cattcaccac gcaaataata agataaaata 5820 ttttcatttt tattctttaa aatgcaataa aaaaggagga tttcctcccc ctttcgttca 5880 aaacctgtag tttctggcta aat 5903 <210> 1461 <211> 177 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(72..602) <400> 1461 Met Lys Phe Lys Arg Leu Leu His Ser Gly Ile Ala Ser Leu Ser Leu 1 5 10 15 Val Ala Cys Gly Val Asn Ala Ala Thr Asp Leu Gly Pro Ala Gly Asp 20 25 30 Ile His Phe Ser Ile Thr Ile Thr Thr Lys Ala Cys Glu Met Glu Lys 35 40 45 Ser Asp Leu Glu Val Asp Met Gly Thr Met Thr Leu Gln Lys Pro Ala 50 55 60 Ala Val Gly Thr Val Leu Ser Lys Lys Asp Phe Thr Ile Glu Leu Lys 65 70 75 80 Glu Cys Asp Gly Ile Ser Lys Ala Thr Val Glu Met Asp Ser Gln Ser 85 90 95 Asp Ser Asp Asp Asp Ser Met Phe Ala Leu Glu Ala Gly Gly Ala Thr 100 105 110 Gly Val Ala Leu Lys Ile Glu Asp Asp Lys Gly Thr Gln Gln Val Pro 115 120 125 Lys Gly Ser Ser Gly Thr Pro Ile Glu Trp Ala Ile Asp Gly Glu Thr 130 135 140 Thr Ser Leu His Tyr Gln Ala Ser Tyr Val Val Val Asn Thr Gln Ala 145 150 155 160 Thr Gly Gly Thr Ala Asn Ala Leu Val Asn Phe Ser Ile Thr Tyr Glu 165 170 175 * <210> 1462 <211> 352 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(607..1662) <400> 1462 Met Lys Ala Ala Ile Ala Leu Ser Leu Leu Gly Cys Val Phe Gly Phe 1 5 10 15 Ser Gly Lys Ala Phe Ala Gly Asp Ala Trp Gly Pro Cys Thr Pro Ala 20 25 30 Asp Gly Thr Thr Tyr His Tyr Asn Val Asp Val Asp Val Gly Ile Pro 35 40 45 Asp Ala Ala Lys Asn Val Ala Gly Thr Val Leu Pro Asp Val Leu Asn 50 55 60 Trp Ser Asn Gly Gln Asn Val Ser Leu Ile Cys Glu Cys Pro Asp Ser 65 70 75 80 Tyr Lys Asn Glu Lys Asp Thr Leu Val Gln Gly Val Ser Met Leu Pro 85 90 95 Pro Ser Gly Arg Thr Val Asp Ser Met Lys Tyr Tyr Thr Leu Thr Glu 100 105 110 Glu Leu Glu Val Ala Thr Asn Ile Arg Ile Ser Thr Ser Val Tyr Gly 115 120 125 Phe Val Pro Phe Lys Asn Gln Gln Ala Leu Gln Thr Thr Gly Cys Asn 130 135 140 Lys Val Ile Thr Thr Pro Tyr Met Gly Gly Ala Gly Leu Leu Ser Phe 145 150 155 160 Ala Ile Thr Lys Pro Phe Ile Gly Asp Ser Val Ile Pro Leu Thr Leu 165 170 175 Ile Ala Glu Leu Tyr Ala Ser Lys Thr Asn Lys Asp Tyr Gly Thr Ile 180 185 190 Pro Ile Ser Ser Val Ser Ile Gln Gly Arg Val Thr Val Thr Gln Asp 195 200 205 Cys Glu Ile Lys Pro Gly Thr Val Leu Asp Val Pro Phe Gly Glu Phe 210 215 220 Pro Ser Ser Ala Phe Lys Asn Arg Gln Gly Gln Met Pro Glu Gly Ala 225 230 235 240 Thr Glu Gln Glu Ile Asn Leu Ser Phe Asp Cys Asn Asn Ile Ser Asp 245 250 255 Gly Ile Lys Val Ala Leu Arg Leu Glu Gly Ala Thr Asn Ala Asp Asp 260 265 270 Pro Arg Ala Val Asp Met Gly Asn Pro Asp Ile Gly Val Leu Val Lys 275 280 285 Asp Ser Ser Gly Lys Ile Leu Val Pro Asn Asp Ser Ser Ser Thr Thr 290 295 300 Leu Leu Asn Leu Ser Ser Leu Asp Ser Lys Thr His Arg Asn Ala Ala 305 310 315 320 Ile Arg Leu Leu Ala Leu Pro Ile Ser Thr Thr Gly Lys Ala Pro Lys 325 330 335 Gly Gly Thr Phe Glu Gly Val Thr Thr Ile Tyr Leu Glu Met Glu * 340 345 350 <210> 1463 <211> 486 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1677..3134) <400> 1463 Val Pro Ile Phe Gln Arg Glu Gly His Leu Lys Tyr Ser Phe Ala Ala 1 5 10 15 Gly Glu Tyr Gln Ala Gly Asn Tyr Asp Ser Ala Ser Pro Arg Phe Gly 20 25 30 Gln Leu Asp Leu Ile Tyr Gly Leu Pro Trp Gly Met Thr Ala Tyr Gly 35 40 45 Gly Val Leu Ile Ser Asn Asn Tyr Asn Ala Phe Thr Leu Gly Ile Gly 50 55 60 Lys Asn Phe Gly Tyr Ile Gly Ala Ile Ser Ile Asp Val Thr Gln Ala 65 70 75 80 Lys Ser Glu Leu Asn Asn Asp Arg Asp Ser Gln Gly Gln Ser Tyr Arg 85 90 95 Phe Leu Tyr Ser Lys Ser Phe Glu Ser Gly Thr Asp Phe Arg Leu Ala 100 105 110 Gly Tyr Arg Tyr Ser Thr Ser Gly Phe Tyr Thr Phe Gln Glu Ala Thr 115 120 125 Asp Val Arg Ser Asp Ala Asp Ser Asp Tyr Asn Arg Tyr His Lys Arg 130 135 140 Ser Glu Ile Gln Gly Asn Leu Thr Gln Gln Leu Gly Ala Tyr Gly Ser 145 150 155 160 Val Tyr Leu Asn Leu Thr Gln Gln Asp Tyr Trp Asn Asp Ala Gly Lys 165 170 175 Gln Asn Thr Val Ser Ala Gly Tyr Asn Gly Arg Ile Gly Lys Val Ser 180 185 190 Tyr Ser Ile Ala Tyr Ser Trp Asn Lys Ser Pro Glu Trp Asp Glu Ser 195 200 205 Asp Arg Leu Trp Ser Phe Asn Ile Ser Val Pro Leu Gly Arg Ala Trp 210 215 220 Ser Asn Tyr Arg Val Thr Thr Asp Gln Asp Gly Arg Thr Asn Gln Gln 225 230 235 240 Val Gly Val Ser Gly Thr Leu Leu Glu Asp Arg Asn Leu Ser Tyr Ser 245 250 255 Val Gln Glu Gly Tyr Ala Ser Asn Gly Val Gly Asn Ser Gly Asn Ala 260 265 270 Asn Val Gly Tyr Gln Gly Gly Ser Gly Asn Val Asn Val Gly Tyr Ser 275 280 285 Tyr Gly Lys Asp Tyr Arg Gln Leu Asn Tyr Ser Val Arg Gly Gly Val 290 295 300 Ile Val His Ser Glu Gly Val Thr Leu Ser Gln Pro Leu Gly Glu Thr 305 310 315 320 Met Thr Leu Ile Ser Val Pro Gly Ala Arg Asn Ala Arg Val Val Asn 325 330 335 Asn Gly Gly Val Gln Val Asp Trp Met Gly Asn Ala Ile Val Pro Tyr 340 345 350 Ala Met Pro Tyr Arg Glu Asn Glu Ile Ser Leu Arg Ser Asp Ser Leu 355 360 365 Gly Asp Asp Val Asp Val Glu Asn Ala Phe Gln Lys Val Val Pro Thr 370 375 380 Arg Gly Ala Ile Val Arg Ala Arg Phe Asp Thr Arg Val Gly Tyr Arg 385 390 395 400 Val Leu Met Thr Leu Leu Arg Ser Ala Gly Ser Pro Val Pro Phe Gly 405 410 415 Ala Thr Ala Thr Leu Ile Thr Asp Lys Gln Asn Glu Val Ser Ser Ile 420 425 430 Val Gly Glu Glu Gly Gln Leu Tyr Ile Ser Gly Met Pro Glu Glu Gly 435 440 445 Arg Val Leu Ile Lys Trp Gly Asn Asp Ala Ser Gln Gln Cys Val Ala 450 455 460 Pro Tyr Lys Leu Ser Leu Glu Leu Lys Gln Gly Gly Ile Ile Pro Val 465 470 475 480 Ser Ala Asn Cys Gln * 485 <210> 1464 <211> 368 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3147..4250) <400> 1464 Met Ser Arg Lys Thr Val Ser Arg Thr Phe Ser Ser Phe Ser Ile Ser 1 5 10 15 Val Val Ala Val Ala Val Ala Ser Thr Phe Ser Ala His Ala Gly Lys 20 25 30 Phe Asn Pro Lys Phe Leu Glu Asp Val Gln Gly Val Gly Gln His Val 35 40 45 Asp Leu Thr Met Phe Glu Lys Gly Gln Glu Gln Gln Leu Pro Gly Ile 50 55 60 Tyr Arg Val Ser Val Tyr Val Asn Glu Gln Arg Met Glu Thr Arg Thr 65 70 75 80 Leu Glu Phe Lys Glu Ala Thr Glu Ala Gln Arg Lys Ala Met Gly Glu 85 90 95 Ser Leu Val Pro Cys Leu Ser Arg Thr Gln Leu Ala Glu Met Gly Val 100 105 110 Arg Val Glu Ser Phe Pro Ala Leu Asn Leu Val Ser Ala Glu Ala Cys 115 120 125 Val Pro Phe Asp Glu Ile Ile Pro Leu Ala Ser Ser His Phe Asp Phe 130 135 140 Ser Glu Gln Lys Leu Val Leu Ser Phe Pro Gln Ala Ala Met His Gln 145 150 155 160 Val Ala Arg Gly Thr Val Pro Glu Ser Leu Trp Asp Glu Gly Ile Pro 165 170 175 Ala Leu Leu Leu Asp Tyr Ser Phe Ser Gly Ser Asn Ser Glu Tyr Asp 180 185 190 Ser Thr Gly Ser Ser Ser Ser Tyr Val Asp Asp Asn Gly Thr Val His 195 200 205 His Asp Asp Gly Lys Asp Thr Leu Lys Ser Asp Ser Tyr Tyr Leu Asn 210 215 220 Leu Arg Ser Gly Leu Asn Leu Gly Ala Trp Arg Leu Arg Asn Tyr Ser 225 230 235 240 Thr Trp Ser His Ser Gly Gly Lys Ala Gln Trp Asp Asn Ile Gly Thr 245 250 255 Ser Leu Ser Arg Ala Ile Ile Pro Phe Lys Ala Gln Leu Thr Met Gly 260 265 270 Asp Thr Ala Thr Ala Gly Asp Ile Phe Asp Ser Val Gln Met Arg Gly 275 280 285 Ala Met Leu Ala Ser Asp Glu Glu Met Leu Pro Asp Ser Gln Arg Gly 290 295 300 Phe Ala Pro Ile Val Arg Gly Ile Ala Lys Ser Asn Ala Glu Val Ser 305 310 315 320 Ile Glu Gln Asn Gly Tyr Val Ile Tyr Arg Thr Tyr Val Gln Pro Gly 325 330 335 Ala Phe Glu Ile Asn Asp Leu Tyr Pro Thr Ala Asn Ser Gly Asp Leu 340 345 350 Thr Val Ile Ile Lys Glu Ala Asp Gly Ser Glu Gln Arg Phe Ile * 355 360 365 <210> 1465 <211> 230 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4279..4968) <400> 1465 Met Met Lys Ser Lys Phe Val Ala Leu Ala Leu Ser Leu Phe Leu Ser 1 5 10 15 Gln Ser Val Leu Ala Gly Gly Val Gly Leu Ser Ser Thr Arg Val Ile 20 25 30 Tyr Asp Gly Ser Lys Lys Glu Ala Ser Leu Thr Val Gln Asn Lys Ser 35 40 45 Lys Thr Glu Glu Phe Leu Ile Gln Ser Trp Val Asp Asp Ala Ala Gly 50 55 60 Ser Lys Lys Thr Pro Phe Ile Ile Thr Pro Pro Leu Phe Lys Leu Asp 65 70 75 80 Pro Glu Lys Asn Asn Ile Leu Arg Ile Val Asn Ile Thr Pro Gly Leu 85 90 95 Pro Gln Asp Arg Glu Ser Val Tyr Trp Val Asn Val Lys Ala Ile Pro 100 105 110 Ser Lys Ser Asp Asp Ser Glu Asn Lys Asn Val Leu Gln Ile Ala Val 115 120 125 Arg Thr Arg Ile Lys Leu Phe Tyr Arg Pro Ala Gly Leu Lys Gly Asp 130 135 140 Val Lys Thr Ala Pro Asn Glu Leu Arg Phe Thr Arg Asn Gly Asn Gln 145 150 155 160 Leu Arg Val Asp Asn Pro Thr Val Phe Asn Ile Thr Phe Asn Gln Phe 165 170 175 Phe Ala Asn Asp Lys Glu Ile Glu Lys Ala Gly Met Val Pro Ala Lys 180 185 190 Gly Ala Leu Asn Ile Thr Leu Pro Ala Gly Val Gly Ser Val Ser Lys 195 200 205 Ile Lys Tyr Asn Thr Ile Asn Asp Phe Gly Ser Ser Ala Glu Met Ile 210 215 220 Thr Lys Asn Val Asp * 225 <210> 1466 <211> 179 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5030..5566) <400> 1466 Met Glu Phe Phe Met Lys Lys Val Val Phe Ala Leu Thr Ala Leu Ala 1 5 10 15 Leu Thr Ser Gly Thr Val Phe Ala Ala Glu Ser Gly Asp Gly Thr Val 20 25 30 Lys Phe Thr Gly Glu Ile Val Asp Ser Pro Cys Val Leu Ser Val Asp 35 40 45 Ser Gln Asn Gln Glu Val Val Leu Gly Gln Val Gln Lys Ser Val Phe 50 55 60 Ala Ala Val Gly Asp Lys Ser Pro Ala Lys Pro Phe Glu Ile Lys Leu 65 70 75 80 Glu Asp Cys Asp Thr Thr Thr Met Lys Lys Ala Asn Val Ser Phe Ser 85 90 95 Gly Val Gly Asp Ala Asp Lys Ser Asp Leu Ile Ser Val Ser Thr Glu 100 105 110 Ala Gly Ala Ala Lys Gly Val Gly Ile Gly Ile Tyr Asp Asn Ser Asn 115 120 125 Thr Leu Val Ala Leu Asn Gly Gly Lys Ala Ser Val Asp Leu Ser Lys 130 135 140 Gly Gln Thr Val Leu Tyr Phe Thr Ala Asn Tyr Val Ser Thr Leu Ala 145 150 155 160 Thr Val Thr Thr Gly Tyr Gly Asn Ala Gln Val Asp Phe Asn Leu Ser 165 170 175 Tyr Glu * <210> 1467 <211> 5662 <212> DNA <213> Escherichia coli O157:H7 <400> 1467 cgtttatgcc ggctggggta caaaaacaat aaattcaata tattgcaggg gttatatagg 60 cctgataagc gcagcacatc cggcaatgta gcgtttgtta tcagtctgaa aggataccct 120 cgtaaaaggg tatcctttaa taacaactgc tgaaattaaa gtgatttacg gcaggcggtc 180 agttgggggc tggaatcagc gtcgcttccg gtcataccgg ttagcatctg cacatagtag 240 tgccgactgt aatcatcaga ttcacttgtc cagtaagctc ccggtgtaaa ttgcgaatta 300 ctggaaaacg ctccaacgtt cccccattca ccatacagtg atccctgcgt gcgtttgttt 360 tcgccagacg tcaaatgtgt gatgccagga agattatatc catcattttt agcatgacag 420 agcgcattgg cagctagcca gatattggta tgatttccat tattcaccca ccagcctttc 480 agcttaatta aggtctggta ggttgtacct ccttgtcggg gaacagcgct tattgtgact 540 gacgtttgat cgccgatatt tgcgaaagaa actttacccg aagcatcgac agacacccaa 600 ccctgtgaac ttgaaaacat ataatcatca acggttttac ccgcttcaaa gttatcattg 660 ttgagtgtgt aatacgctcc tgcaaagcct tcgctcggga atttagccgt ggagaaggta 720 tggttgtttg cagtgacatg accggacatt tcttttatcg attggatgag attcagcgat 780 atgcttaagt ttgcctgatg aaccccgttc agcatgggaa tgagtgtcgc tgttccctct 840 tttccgccag tgacagtcac ggtgtactcg ccataatttc tttggctgta atcaatatcg 900 ctcaacttga gaaagttcac gaaggggcct gactggacaa attccagatg atcagacgtc 960 actatcgggt taccgtactt gtcttgcaat gttagcgtaa gttttgcgct ctgctggtag 1020 tcagccttca gagtgtcaac atcggatttc aaaattgact tactttcatc ggccgtgccg 1080 gcaaccaatg taatggttgc ggattggttg gctgtgccag gaacttgcac attgactgtt 1140 aaggtttctg ccaatgtact ggttattgtc gccgtgactt gcccggactg atcggtacgc 1200 gtagttggaa tattaactac cgggctgcct ttggtgtcta agccatgact aatatcgaca 1260 ccttcaaccg ggaatccgta atcatcttct actcgtgaag tgatggtgct gctatcgatg 1320 ccgtcggcgg tgatggtgtc aggagaagcc acgacgctca caacatgtgc cgttttagca 1380 tctgccttaa ccgcaaccgt tacctggctc tgaacgggaa catctttgcc cattatggcc 1440 gtaacggtat agacattcac tttgtcactg gtcagcgtca ctttggcctg acctgactgg 1500 tcagtaagga cttcccctgt attgcttagc gttgcacctt caggcgttac gctaaaggtg 1560 ataatttgcc ctggcatcaa ttcaccccgc gcatttctcg ccgttgcggt cagcgtaata 1620 ccctcactat tatggaccgt agtttctggt ttcgatgatg ttaactcgag tttgccattt 1680 gccacattca cgtcaacctt actactactg ttattgtcca gcgttgccgt cacctgataa 1740 accccaggtt gggtgctgag aaggttaacg tacgcataac cgttattatc ggtgtaagcc 1800 gtatcgccta tcgtaatgtt agttgttggc tgcgcactta atctgacgcg ttgacccgcg 1860 attacattgt taaacgcgtc ctggacgagt atccgtagcg tgatgttttc gcccaccgtt 1920 atcgtttttt cggctccggt tatacttatt accttcgccg aactttcatc cggtagcact 1980 gataaactaa acgttttatt atcggaagct tgcgctttcc ggctcaccac gacgttatgt 2040 tgtccggcaa tattgctggt cattgttacc gtcgcctgac ccagcgtatt ggtggtgact 2100 tctgtttcgc ttagagtgac atcgttactc tggaaagtga ccaactggtc tttaagcgga 2160 ttttggtaag cgtccaggat cgttgccgtc agggtactcc ccgtactgtt acccgcaaca 2220 atggaattta atgaggcagt cagcggctgg agctgcgcac tgtttgtatc cccaataaaa 2280 gtgacttgct gataagcaac ggtattattt ctggtcagcg tcgccgtaac tgtaaactca 2340 cccgcttttg tgcctcgcaa tgtgaccacg gcatcaccgt ttgcatcggt gcgggcggtt 2400 tcactactta gcgtgaagtt cccggtcatg gaggctggca aggtaaattt cacatcctca 2460 tccggcaacg ggtgtccata aacatctttc acactggcag tcagggtaac gatatttgta 2520 ttgttagcga tcgcactgcc cgacccggca ttcaaggtca ttaccgattg ttccctgttt 2580 gggaccacgg tgatcgtgac cgactggtga atatttttat ccacctcaag cgaggcatcg 2640 acggaatagc taccagcttt tgaactggtc aggtgcaccc gcacaatacc ggactggtct 2700 gttgtggcgg tcgtgttgtc cagttgcgag ccaccaggtg ccacaaaatt cactttcata 2760 tcttttaacg ggttgttatg aaagtctgtg atgatggcgg tcagagtact gccctggctg 2820 ttgccagcaa taatggtatc tggatcggca accagttgtt tgaattttgg cgtactcgaa 2880 tcgctaacga atttcgcaat tatccgttgt gaaaaaccat ttggcagcgt ggcgctaatc 2940 gtattttctt ccgcaacctg acttaccatg tttattgtgg caacaccata tgcatccgta 3000 ttttgctgcg gcggttcgac aaactccgcg cttccttttt cattcttaaa ggtgacctga 3060 tgatttgtca ggggattatc actctcatca gtgacgttga tcgtgagggt attaaatgtc 3120 tttttatcgg cgtaaacgtc attatttgtc gctgataatg tggcaacgcg agccttattc 3180 tggtttgcct caatgttata aatatgcgat tgcagtggag cattccagtt gtgaaggcta 3240 agttgtgccc ttagtgcagt cccttgctta taggccggat aattcgcggc ataaaccccc 3300 ggctgctctt cgtgccagac aatcgtggcg ccaggtttgc tgttttcgac agtaacggct 3360 tttaccaatt cctctttttg atatgcaacc ggttgattgc tatcgtcttt cagttccacc 3420 ctaaccttga tgtcgtctcc ggcataatac gatacgttat caattgttat tgatgaatgg 3480 tcgcgggatg agacaacagg gacgatatta acgacgatgg attcttttac cgcactctca 3540 ccgttaattt gcggcgtcag tgttactgaa cctgatgtcg ttccggcggt cagtatctgt 3600 gtgtaactac catcaccgtt atctgtccag tcagacaggg tgatatcctg aacgccttca 3660 ctgcgggttt gcagcgccag ccccggcacc ggagttccgt cggaatcgtg cgcagtaacg 3720 gtcaatgtgg tcgtcgattt tttatctgca gccacggtta gcggattgac ggataacaga 3780 gaatctttct ggcttaatgt cggagcctga ataactacca tgctttgttc atgccgtgac 3840 aggttacctt ttacatcctc ggcggtaacg tctatcgacc atgtattatc ggtttctggg 3900 gtgttagtga agcggtaacc tggcagcgtg accgtgatat cttttccaga cgtgctgact 3960 ttacctccgg cagcttccag cgcagcggct tcgatgttat agcctttaag ggcatatttg 4020 gtctgtagcg aggaaaccag cggttttatt tctccagact tccctttcac cggatccagc 4080 agactcaggc gaatcagctc tttcttgcgg tattccagaa cgatgttgtt gttgcgatca 4140 atcaggtcat aacgactacc ggccagactg cgccgtccgg ccacttcgtc cggattaagc 4200 tgtttctgca ttgaactgct gggttgccag gtcagatcaa cggcaaaacg tgtgtcattt 4260 tcaccttgct tcccctgacg ctgttccgca ctgagagtca gaagcgggaa gggggtatag 4320 ttgaggcctg cggtaatagc atgggggtta ctttgacgat cattcttgtc aaacagcgcc 4380 acttcatcgc catagtattg ttcatagacc agttttcccc ccagttgtgg ccaggcaggt 4440 aaccagcctt ccgcgcgtaa atcccagccg ttggccgggc gggcttcgaa gtcgttatcc 4500 aattctggtg cgctacgcca gccggtcagg ccgatataag cgttgctgct caacttcaga 4560 taatcacgcc agtattctgc gccaagccct gcgcgggagt gatagcggct caggtcgtgg 4620 tcaaaaaaaa ggttgatgcc tgacatccag ctggaggtga aatgacgcca gcccaaaccg 4680 gtgttgatct gggtacgatc gtctgttcgg tgaagggtat gctggctgaa gagcagataa 4740 tcaggtgtgt cataccacgg atgcaggaag tcgaattgcg aatttttcag gctaaaatct 4800 tcatccacac ccagagagat tctcgcagta ccaaagttat ttaaccaatc agtcatcgcg 4860 cctgaggctt ctgaagacgc ccaaccacgc gccatgccgc tggcctgctc actattcata 4920 tcttgtgaaa gcagagtgcc aactcgctgc gaggtgctgg ctatttgatt ctccagcgtg 4980 ttttcgccat tcgcaggcgg tacggcattt tgttgctcat ggcttttctg cgaggttgtt 5040 gccggaacat ccagttcttc accctggcgc acgttatcaa agccgcgagc aaaagtacgg 5100 aactgattaa gacgacgaag ctcctccagt gaaataccga agcgattagc aacgctttgc 5160 gctgattcca gcgcaccaag cgtgtaaggc acagtattat tttctagtag aggggggggc 5220 agatgaaact gtcgtctgag gtttagcatg taccacattt tgtgccgtcg ccatgacggg 5280 gaaaaaaaat tgtgtaaata aacaaactcc ggcggtcagg cggcgtattt tgtcacccag 5340 accacataaa gagttttgat cattattttt tatttgatgc gcatttgtcg aagccatagt 5400 gaccttccgt gaaaaaacag aattaaactt gttttttcta gcacggagat ataatgcgat 5460 cctgactata atatgaccag aaataatgaa ttagccgtgg aattgctaaa ccaggaataa 5520 taccggcggt ggctgagtac ctccaaagaa aaaggatatt ttaattattt tacgtgatgt 5580 gctgaaaagt taaattagtt aaattactta agaataattc gtatgcaatt tgaatatttg 5640 catcccgcag attaatgctg cg 5662 <210> 1468 <211> 1580 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(156..4895) <400> 1468 Met Ala Arg Gly Trp Ala Ser Ser Glu Ala Ser Gly Ala Met Thr Asp 1 5 10 15 Trp Leu Asn Asn Phe Gly Thr Ala Arg Ile Ser Leu Gly Val Asp Glu 20 25 30 Asp Phe Ser Leu Lys Asn Ser Gln Phe Asp Phe Leu His Pro Trp Tyr 35 40 45 Asp Thr Pro Asp Tyr Leu Leu Phe Ser Gln His Thr Leu His Arg Thr 50 55 60 Asp Asp Arg Thr Gln Ile Asn Thr Gly Leu Gly Trp Arg His Phe Thr 65 70 75 80 Ser Ser Trp Met Ser Gly Ile Asn Leu Phe Phe Asp His Asp Leu Ser 85 90 95 Arg Tyr His Ser Arg Ala Gly Leu Gly Ala Glu Tyr Trp Arg Asp Tyr 100 105 110 Leu Lys Leu Ser Ser Asn Ala Tyr Ile Gly Leu Thr Gly Trp Arg Ser 115 120 125 Ala Pro Glu Leu Asp Asn Asp Phe Glu Ala Arg Pro Ala Asn Gly Trp 130 135 140 Asp Leu Arg Ala Glu Gly Trp Leu Pro Ala Trp Pro Gln Leu Gly Gly 145 150 155 160 Lys Leu Val Tyr Glu Gln Tyr Tyr Gly Asp Glu Val Ala Leu Phe Asp 165 170 175 Lys Asn Asp Arg Gln Ser Asn Pro His Ala Ile Thr Ala Gly Leu Asn 180 185 190 Tyr Thr Pro Phe Pro Leu Leu Thr Leu Ser Ala Glu Gln Arg Gln Gly 195 200 205 Lys Gln Gly Glu Asn Asp Thr Arg Phe Ala Val Asp Leu Thr Trp Gln 210 215 220 Pro Ser Ser Ser Met Gln Lys Gln Leu Asn Pro Asp Glu Val Ala Gly 225 230 235 240 Arg Arg Ser Leu Ala Gly Ser Arg Tyr Asp Leu Ile Asp Arg Asn Asn 245 250 255 Asn Ile Val Leu Glu Tyr Arg Lys Lys Glu Leu Ile Arg Leu Ser Leu 260 265 270 Leu Asp Pro Val Lys Gly Lys Ser Gly Glu Ile Lys Pro Leu Val Ser 275 280 285 Ser Leu Gln Thr Lys Tyr Ala Leu Lys Gly Tyr Asn Ile Glu Ala Ala 290 295 300 Ala Leu Glu Ala Ala Gly Gly Lys Val Ser Thr Ser Gly Lys Asp Ile 305 310 315 320 Thr Val Thr Leu Pro Gly Tyr Arg Phe Thr Asn Thr Pro Glu Thr Asp 325 330 335 Asn Thr Trp Ser Ile Asp Val Thr Ala Glu Asp Val Lys Gly Asn Leu 340 345 350 Ser Arg His Glu Gln Ser Met Val Val Ile Gln Ala Pro Thr Leu Ser 355 360 365 Gln Lys Asp Ser Leu Leu Ser Val Asn Pro Leu Thr Val Ala Ala Asp 370 375 380 Lys Lys Ser Thr Thr Thr Leu Thr Val Thr Ala His Asp Ser Asp Gly 385 390 395 400 Thr Pro Val Pro Gly Leu Ala Leu Gln Thr Arg Ser Glu Gly Val Gln 405 410 415 Asp Ile Thr Leu Ser Asp Trp Thr Asp Asn Gly Asp Gly Ser Tyr Thr 420 425 430 Gln Ile Leu Thr Ala Gly Thr Thr Ser Gly Ser Val Thr Leu Thr Pro 435 440 445 Gln Ile Asn Gly Glu Ser Ala Val Lys Glu Ser Ile Val Val Asn Ile 450 455 460 Val Pro Val Val Ser Ser Arg Asp His Ser Ser Ile Thr Ile Asp Asn 465 470 475 480 Val Ser Tyr Tyr Ala Gly Asp Asp Ile Lys Val Arg Val Glu Leu Lys 485 490 495 Asp Asp Ser Asn Gln Pro Val Ala Tyr Gln Lys Glu Glu Leu Val Lys 500 505 510 Ala Val Thr Val Glu Asn Ser Lys Pro Gly Ala Thr Ile Val Trp His 515 520 525 Glu Glu Gln Pro Gly Val Tyr Ala Ala Asn Tyr Pro Ala Tyr Lys Gln 530 535 540 Gly Thr Ala Leu Arg Ala Gln Leu Ser Leu His Asn Trp Asn Ala Pro 545 550 555 560 Leu Gln Ser His Ile Tyr Asn Ile Glu Ala Asn Gln Asn Lys Ala Arg 565 570 575 Val Ala Thr Leu Ser Ala Thr Asn Asn Asp Val Tyr Ala Asp Lys Lys 580 585 590 Thr Phe Asn Thr Leu Thr Ile Asn Val Thr Asp Glu Ser Asp Asn Pro 595 600 605 Leu Thr Asn His Gln Val Thr Phe Lys Asn Glu Lys Gly Ser Ala Glu 610 615 620 Phe Val Glu Pro Pro Gln Gln Asn Thr Asp Ala Tyr Gly Val Ala Thr 625 630 635 640 Ile Asn Met Val Ser Gln Val Ala Glu Glu Asn Thr Ile Ser Ala Thr 645 650 655 Leu Pro Asn Gly Phe Ser Gln Arg Ile Ile Ala Lys Phe Val Ser Asp 660 665 670 Ser Ser Thr Pro Lys Phe Lys Gln Leu Val Ala Asp Pro Asp Thr Ile 675 680 685 Ile Ala Gly Asn Ser Gln Gly Ser Thr Leu Thr Ala Ile Ile Thr Asp 690 695 700 Phe His Asn Asn Pro Leu Lys Asp Met Lys Val Asn Phe Val Ala Pro 705 710 715 720 Gly Gly Ser Gln Leu Asp Asn Thr Thr Ala Thr Thr Asp Gln Ser Gly 725 730 735 Ile Val Arg Val His Leu Thr Ser Ser Lys Ala Gly Ser Tyr Ser Val 740 745 750 Asp Ala Ser Leu Glu Val Asp Lys Asn Ile His Gln Ser Val Thr Ile 755 760 765 Thr Val Val Pro Asn Arg Glu Gln Ser Val Met Thr Leu Asn Ala Gly 770 775 780 Ser Gly Ser Ala Ile Ala Asn Asn Thr Asn Ile Val Thr Leu Thr Ala 785 790 795 800 Ser Val Lys Asp Val Tyr Gly His Pro Leu Pro Asp Glu Asp Val Lys 805 810 815 Phe Thr Leu Pro Ala Ser Met Thr Gly Asn Phe Thr Leu Ser Ser Glu 820 825 830 Thr Ala Arg Thr Asp Ala Asn Gly Asp Ala Val Val Thr Leu Arg Gly 835 840 845 Thr Lys Ala Gly Glu Phe Thr Val Thr Ala Thr Leu Thr Arg Asn Asn 850 855 860 Thr Val Ala Tyr Gln Gln Val Thr Phe Ile Gly Asp Thr Asn Ser Ala 865 870 875 880 Gln Leu Gln Pro Leu Thr Ala Ser Leu Asn Ser Ile Val Ala Gly Asn 885 890 895 Ser Thr Gly Ser Thr Leu Thr Ala Thr Ile Leu Asp Ala Tyr Gln Asn 900 905 910 Pro Leu Lys Asp Gln Leu Val Thr Phe Gln Ser Asn Asp Val Thr Leu 915 920 925 Ser Glu Thr Glu Val Thr Thr Asn Thr Leu Gly Gln Ala Thr Val Thr 930 935 940 Met Thr Ser Asn Ile Ala Gly Gln His Asn Val Val Val Ser Arg Lys 945 950 955 960 Ala Gln Ala Ser Asp Asn Lys Thr Phe Ser Leu Ser Val Leu Pro Asp 965 970 975 Glu Ser Ser Ala Lys Val Ile Ser Ile Thr Gly Ala Glu Lys Thr Ile 980 985 990 Thr Val Gly Glu Asn Ile Thr Leu Arg Ile Leu Val Gln Asp Ala Phe 995 1000 1005 Asn Asn Val Ile Ala Gly Gln Arg Val Arg Leu Ser Ala Gln Pro Thr 1010 1015 1020 Thr Asn Ile Thr Ile Gly Asp Thr Ala Tyr Thr Asp Asn Asn Gly Tyr 1025 1030 1035 1040 Ala Tyr Val Asn Leu Leu Ser Thr Gln Pro Gly Val Tyr Gln Val Thr 1045 1050 1055 Ala Thr Leu Asp Asn Asn Ser Ser Ser Lys Val Asp Val Asn Val Ala 1060 1065 1070 Asn Gly Lys Leu Glu Leu Thr Ser Ser Lys Pro Glu Thr Thr Val His 1075 1080 1085 Asn Ser Glu Gly Ile Thr Leu Thr Ala Thr Ala Arg Asn Ala Arg Gly 1090 1095 1100 Glu Leu Met Pro Gly Gln Ile Ile Thr Phe Ser Val Thr Pro Glu Gly 1105 1110 1115 1120 Ala Thr Leu Ser Asn Thr Gly Glu Val Leu Thr Asp Gln Ser Gly Gln 1125 1130 1135 Ala Lys Val Thr Leu Thr Ser Asp Lys Val Asn Val Tyr Thr Val Thr 1140 1145 1150 Ala Ile Met Gly Lys Asp Val Pro Val Gln Ser Gln Val Thr Val Ala 1155 1160 1165 Val Lys Ala Asp Ala Lys Thr Ala His Val Val Ser Val Val Ala Ser 1170 1175 1180 Pro Asp Thr Ile Thr Ala Asp Gly Ile Asp Ser Ser Thr Ile Thr Ser 1185 1190 1195 1200 Arg Val Glu Asp Asp Tyr Gly Phe Pro Val Glu Gly Val Asp Ile Ser 1205 1210 1215 His Gly Leu Asp Thr Lys Gly Ser Pro Val Val Asn Ile Pro Thr Thr 1220 1225 1230 Arg Thr Asp Gln Ser Gly Gln Val Thr Ala Thr Ile Thr Ser Thr Leu 1235 1240 1245 Ala Glu Thr Leu Thr Val Asn Val Gln Val Pro Gly Thr Ala Asn Gln 1250 1255 1260 Ser Ala Thr Ile Thr Leu Val Ala Gly Thr Ala Asp Glu Ser Lys Ser 1265 1270 1275 1280 Ile Leu Lys Ser Asp Val Asp Thr Leu Lys Ala Asp Tyr Gln Gln Ser 1285 1290 1295 Ala Lys Leu Thr Leu Thr Leu Gln Asp Lys Tyr Gly Asn Pro Ile Val 1300 1305 1310 Thr Ser Asp His Leu Glu Phe Val Gln Ser Gly Pro Phe Val Asn Phe 1315 1320 1325 Leu Lys Leu Ser Asp Ile Asp Tyr Ser Gln Arg Asn Tyr Gly Glu Tyr 1330 1335 1340 Thr Val Thr Val Thr Gly Gly Lys Glu Gly Thr Ala Thr Leu Ile Pro 1345 1350 1355 1360 Met Leu Asn Gly Val His Gln Ala Asn Leu Ser Ile Ser Leu Asn Leu 1365 1370 1375 Ile Gln Ser Ile Lys Glu Met Ser Gly His Val Thr Ala Asn Asn His 1380 1385 1390 Thr Phe Ser Thr Ala Lys Phe Pro Ser Glu Gly Phe Ala Gly Ala Tyr 1395 1400 1405 Tyr Thr Leu Asn Asn Asp Asn Phe Glu Ala Gly Lys Thr Val Asp Asp 1410 1415 1420 Tyr Met Phe Ser Ser Ser Gln Gly Trp Val Ser Val Asp Ala Ser Gly 1425 1430 1435 1440 Lys Val Ser Phe Ala Asn Ile Gly Asp Gln Thr Ser Val Thr Ile Ser 1445 1450 1455 Ala Val Pro Arg Gln Gly Gly Thr Thr Tyr Gln Thr Leu Ile Lys Leu 1460 1465 1470 Lys Gly Trp Trp Val Asn Asn Gly Asn His Thr Asn Ile Trp Leu Ala 1475 1480 1485 Ala Asn Ala Leu Cys His Ala Lys Asn Asp Gly Tyr Asn Leu Pro Gly 1490 1495 1500 Ile Thr His Leu Thr Ser Gly Glu Asn Lys Arg Thr Gln Gly Ser Leu 1505 1510 1515 1520 Tyr Gly Glu Trp Gly Asn Val Gly Ala Phe Ser Ser Asn Ser Gln Phe 1525 1530 1535 Thr Pro Gly Ala Tyr Trp Thr Ser Glu Ser Asp Asp Tyr Ser Arg His 1540 1545 1550 Tyr Tyr Val Gln Met Leu Thr Gly Met Thr Gly Ser Asp Ala Asp Ser 1555 1560 1565 Ser Pro Gln Leu Thr Ala Cys Arg Lys Ser Leu * 1570 1575 <210> 1469 <211> 64 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4961..5152) <400> 1469 Leu Leu Ile Ala Ser Val Phe His Trp Arg Ser Phe Val Val Leu Ile 1 5 10 15 Ser Ser Val Leu Leu Leu Ala Ala Leu Ile Thr Cys Ala Arg Val Lys 20 25 30 Asn Trp Met Phe Arg Gln Gln Pro Arg Arg Lys Ala Met Ser Asn Lys 35 40 45 Met Pro Tyr Arg Leu Arg Met Ala Lys Thr Arg Trp Arg Ile Lys * 50 55 60 <210> 1470 <211> 67 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(5197..5397) <400> 1470 Met Ala Ser Thr Asn Ala His Gln Ile Lys Asn Asn Asp Gln Asn Ser 1 5 10 15 Leu Cys Gly Leu Gly Asp Lys Ile Arg Arg Leu Thr Ala Gly Val Cys 20 25 30 Leu Phe Thr Gln Phe Phe Phe Pro Val Met Ala Thr Ala Gln Asn Val 35 40 45 Val His Ala Lys Pro Gln Thr Thr Val Ser Ser Ala Pro Pro Ser Thr 50 55 60 Arg Lys * 65 <210> 1471 <211> 5526 <212> DNA <213> Escherichia coli O157:H7 <400> 1471 taatttgcct tttataaatt ctgaaaaatt ccggggtgtt aactcattat catttcctgt 60 tgttgactgg cgctaggctt ctggttctta tttatttcaa aaggatttta cgatgagcgg 120 aaaaccggcg gcgcgtcagg gcgacatgac gcagtatggc ggtagcattg ttcagggttc 180 agccggggtg cgcattggtg cccccaccgg cgtggcctgt tcggtgtgcc ccggcggagt 240 gacgttcggc catccggtca atcccctgct cggtgcaaag gtccttcccg gtgaaaccga 300 catcgccctg cccggcccgc tgccgttcat cctctcccgc acctacagca gttaccggac 360 aaaaacgccc gcgccggtgg ggagcctcgg ccccggctgg aaaatgcctg cggatatccg 420 cttacagctg cgcgataaca cactgatact cagtgataac ggcggcagaa gcctgtattt 480 tgagcacctg tttcccggtg aggacggtta cagccgcagc gagtcactct ggctggtgcg 540 cggcggcgtg gcgaaactgg atgaaggtca ccggctggcc gcactctggc aggcgctgcc 600 ggaagaactc cgcttaagtc cgcatcgtta tctggcgaca aacagtccgc aggggccgtg 660 gtggctgctc ggctggtgtg agcgggtgcc ggaagcggat gaggtgctgc ctgcgccgct 720 gccgccgtac cgggtactga ccgggctggt ggaccgcttc gggcgcacac agacgttcca 780 ccgcgaagcc gccggtgaat tcagcggcga aatcaccggc gtgacggatg gtgccgggcg 840 tcacttccgg ctggtactga ccacgcaggc gcagcgggca gaagaagccc ggcagcaggc 900 catttccggc gggacggaac cgtccgcttt tcctgatacc ctgccgggtt acaccgaata 960 tggccgggac aacggcatcc gtctgtctgc cgtgtggctg acgcacgacc cggaataccc 1020 ggagaattta cctgccgcgc cgctggtgcg ctatggctgg acgccgcgcg gcgaactggc 1080 ggtggtgtat gaccgtagtg gcaaacaggt gcgcagcttt acttacgatg ataaataccg 1140 gggccggatg gtggcgcacc gtcacacggg ccggccggaa atccgttacc gttacgacag 1200 cgacgggcgg gtgacagaac agctaaaccc ggcaggctta agctacacgt atcagtatga 1260 gaaagaccgc atcaccatca ccgacagcct gaaccgccgt gaagtcctgc acacgcaggg 1320 tgaaggcggg ctgaagcggg tggtgaaaaa ggaacacgcg gacggcagcg tcacgcagag 1380 tcagtttgac gcggtgggca ggctcagggc acagacggat gccgcaggca ggacaacaga 1440 atacagcccg gatgtggtga cgggcctcat cacgcgcatc accacgccgg atggcagggc 1500 atcggcgttt tactataacc accacagcca gttaacgtca gccaccgggc ctgacgggct 1560 ggaaatacgc cgggaatatg atgaatgggg ccgtctgatt caggaaactg cccctgacgg 1620 cgatatcacc cgctaccgtt atgataatcc acacagtgac ttaccctgcg caacggaaga 1680 tgccaccggc agccggaaaa ccatgacgtg gagccgttac ggtcagttgc tgagcttcac 1740 cgactgttcc ggttatgtaa cccgttatga ccatgaccgc ttcgggcaga tgacggcggt 1800 gcaccgcgag gaagggctga gtcagtaccg cgcatacgac agccgtggac agttaattgc 1860 cgtgaaagac acgcagggcc atgaaacgcg gtatgaatac aacgccgccg gtgacctgac 1920 caccgtcatt gccccggacg gcagcagaaa cgggacacag tacgatgcgt ggggaaaagc 1980 catctgtacc acgcagggcg gtctgacgcg cagtatggaa tacgatgctg ccggacgggt 2040 catccgcctg accagtgaaa acggcagcca caccaccttc cgttacgatg tactcgaccg 2100 gctgatacag gaaaccggct ttgacggccg cacacagcgt tatcaccacg acctgaccgg 2160 caaacttatc cgcagcgagg atgaggggct ggtcacccac tggcactatg acgaagcaga 2220 ccgcctcacg caccgcaccg tgaagggtga aaccgcagag cgctggcagt atgacgaacg 2280 cggctggctg acagacatca gccatatcag cgaagggcac cgggtgacgg tgcattacgg 2340 gtatgatgag aaaggccggc tgaccggtga gcgtcagacg gtgcatcacc cgcagacgga 2400 agcactgctc tggcagcatg agaccagaca cgcttacaac gcgcaggggc tggcgaaccg 2460 ctgtataccg gacagcctgc ccgccgtgga atggctgacc tatggcagcg gctggctggc 2520 aggcatgaag ctcggcgaca caccgctggt ggatttcacc cgcgaccgcc tgcaccggaa 2580 aacgctgcgc agattcggcc gttatgaact caccaccgct tatacccctg ccgggcagtt 2640 acagagccag cacctgaaca gcctgcagta tgaccgcgat tacacctgga acgacaacgg 2700 cgaactcatc cgcatcagca gcccgcgcca gacccggagt tacagctaca gcgactccgg 2760 caggctgacc ggcgttcaca ccaccgcagc gaatctggat atccgcatcc cgtatgccac 2820 ggacccggca ggtaaccgcc tgcccgaccc ggagctgcac ccggacagca ccctcagcat 2880 gtggccggat aaccgtatcg cccgtgacgc gcactatctt taccggtatg accgtcacgg 2940 caggctgaca gagaaaaccg acctcatccc ggaaggggtt atccgcacgg atgatgagcg 3000 gactcaccgg taccattacg acagtcagca ccggctggtg cactacacgc ggacacaata 3060 tgaagagccg ctggtcgaaa gccgctatct ttacgacccg ctgggccgca gggtggcaaa 3120 acgggtgtgg cgacgtgaac gggacctgac gggctggatg tcgctgtcac ggaaaccgca 3180 agtgacctgg tacggctggg acggcgaccg gctgaccaca atacagaacg acagaacccg 3240 catccagacg atttatcagc cggggagctt cacgccactc atcagggttg aaaccgccac 3300 cggtgagctg gcgaaaacgc agcgccgcag cctggcggat gcgcttcagc agtccggcgg 3360 cgaagacggt ggcagtgtgg tgttcccgcc ggtgctggtg cagatgctcg accggctgga 3420 aagtgaaatc ctggctgacc gggtgagtga ggaaagccgc cgctggctgg catcgtgcgg 3480 cctgactgtg gcgcagatgc aaagccagat ggacccggta tacacgccgg cgcgaaaaat 3540 ccacctgtac cactgcgacc atcgcggcct gccgctggcc cttatcagta aggaaggggc 3600 aacagaatgg tgcgcagaat acgatgagtg gggcaacctg ctgaatgaag agaacccgca 3660 tcagctgcag cagcttatcc gcctgccggg gcagcagtat gatgaggagt ccggcctgta 3720 ttacaaccgc caccgctatt atgacccgct gcaggggagg tatatcactc aggatccgat 3780 tgggctgaag gggggatgga acctgtatac atatccgctg agcccggtga atggcatgga 3840 tccattagga ttatatgaat ttaaatcaaa aaatatagat gatattggaa tatttgcatt 3900 ggcaatgtgt aatggagaat caattaacga gaataaagaa tatggtggac taatatgtaa 3960 gaagcaaggt gaatatttcc ccatgaatcc gataagttca aatgataatg atagtgtaga 4020 cttgcgaaat ataaaatgcc ctgaaggttc agagagagta ggcgattatc acactcacgg 4080 tttttactct gacgataaag gaaataaagt aacaaaagaa aatgatgttt atgatagtct 4140 aaatttttca agcaaagatt taacgaattc ttatatgaat ggaatgggaa aaaaagaatg 4200 cagtagttac ttgggaacac caaataacac ctatctaaaa tataatccca aagctaaagg 4260 gaatggagtt acaattatca ggcaagggag taattaaaat gaaggcaata caatgttgtt 4320 atttccttgc tttagtctcc agtcatttaa tggctggagt tatgagtgat gacaatatat 4380 ttttaagtaa ttcggattta gctgctttat attgtgtggc taaaatattt ccagatggag 4440 aaaatatttt aatatataaa gtaaatataa ttaatgctag ttcaaaaaag atgtattttt 4500 ttatgaaagc ccaacatcaa cccacaatga cataatgggg ggcgggggaa tgtcatatgc 4560 ctatgaatat gatgtaaaat ataatatatg tcatttgaga aaaaagagca gaatgaggta 4620 aaaatctttg gctgtgtatt cagtctggta atcatccaag gaaagctcat cagaagggtg 4680 atgactccaa ttagtagaac atatattttc gataaaagca ccgatgactt tttcatgaag 4740 ttctacagaa ctcgagaaac agatggttct gcgggccaga cgtttgattc gggttctcag 4800 ggtcagattg ttacgctcaa tgtgctgagt aaaaatctta ccagtcagat gcttctcctt 4860 tggtaactct ctagcgtaac taccccattc gtcagtggtc aacatgccga tggtaaaagg 4920 gtaagcagcg ccagcaattc acgacaggtt tcatcagtcc gggggccaaa agtgtaggcc 4980 agaacaccac cagttttcgt gttgtacacg taccagagcc agtgctgtcg cgctttactg 5040 ccgacaaagc tccattgctg actaagtttg cagatgagtg ccacatcagc atgagcgacc 5100 ggggatgacg ttattcttcg tggcgagagt tttttaaagt tcggatgact gtattaatgc 5160 cgattttcag cgtacgggca gtatagcgaa ccccggcacc gttgaaagcc atttcagcga 5220 tttggtcttt aactcccggt ttacggggct cgtaacagta actgagctga aatacccggt 5280 gacagtcacg gccgcggaat cgatcatgtc ttttggggtt ctgcccgcga cggtaaacct 5340 gaacggactg gcaacgggga caatgaaggt taactgtgac catgaaacat ccttaaaagc 5400 gagtattata tccttaattc aactaattgg aggcatcacc gtttaccgga gcgacagctt 5460 gcggaaaggt cgtgcaacta caaagcaaca aacagactac ggcgggaatt atttttttca 5520 tcatcc 5526 <210> 1472 <211> 1395 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(113..4297) <400> 1472 Met Ser Gly Lys Pro Ala Ala Arg Gln Gly Asp Met Thr Gln Tyr Gly 1 5 10 15 Gly Ser Ile Val Gln Gly Ser Ala Gly Val Arg Ile Gly Ala Pro Thr 20 25 30 Gly Val Ala Cys Ser Val Cys Pro Gly Gly Val Thr Phe Gly His Pro 35 40 45 Val Asn Pro Leu Leu Gly Ala Lys Val Leu Pro Gly Glu Thr Asp Ile 50 55 60 Ala Leu Pro Gly Pro Leu Pro Phe Ile Leu Ser Arg Thr Tyr Ser Ser 65 70 75 80 Tyr Arg Thr Lys Thr Pro Ala Pro Val Gly Ser Leu Gly Pro Gly Trp 85 90 95 Lys Met Pro Ala Asp Ile Arg Leu Gln Leu Arg Asp Asn Thr Leu Ile 100 105 110 Leu Ser Asp Asn Gly Gly Arg Ser Leu Tyr Phe Glu His Leu Phe Pro 115 120 125 Gly Glu Asp Gly Tyr Ser Arg Ser Glu Ser Leu Trp Leu Val Arg Gly 130 135 140 Gly Val Ala Lys Leu Asp Glu Gly His Arg Leu Ala Ala Leu Trp Gln 145 150 155 160 Ala Leu Pro Glu Glu Leu Arg Leu Ser Pro His Arg Tyr Leu Ala Thr 165 170 175 Asn Ser Pro Gln Gly Pro Trp Trp Leu Leu Gly Trp Cys Glu Arg Val 180 185 190 Pro Glu Ala Asp Glu Val Leu Pro Ala Pro Leu Pro Pro Tyr Arg Val 195 200 205 Leu Thr Gly Leu Val Asp Arg Phe Gly Arg Thr Gln Thr Phe His Arg 210 215 220 Glu Ala Ala Gly Glu Phe Ser Gly Glu Ile Thr Gly Val Thr Asp Gly 225 230 235 240 Ala Gly Arg His Phe Arg Leu Val Leu Thr Thr Gln Ala Gln Arg Ala 245 250 255 Glu Glu Ala Arg Gln Gln Ala Ile Ser Gly Gly Thr Glu Pro Ser Ala 260 265 270 Phe Pro Asp Thr Leu Pro Gly Tyr Thr Glu Tyr Gly Arg Asp Asn Gly 275 280 285 Ile Arg Leu Ser Ala Val Trp Leu Thr His Asp Pro Glu Tyr Pro Glu 290 295 300 Asn Leu Pro Ala Ala Pro Leu Val Arg Tyr Gly Trp Thr Pro Arg Gly 305 310 315 320 Glu Leu Ala Val Val Tyr Asp Arg Ser Gly Lys Gln Val Arg Ser Phe 325 330 335 Thr Tyr Asp Asp Lys Tyr Arg Gly Arg Met Val Ala His Arg His Thr 340 345 350 Gly Arg Pro Glu Ile Arg Tyr Arg Tyr Asp Ser Asp Gly Arg Val Thr 355 360 365 Glu Gln Leu Asn Pro Ala Gly Leu Ser Tyr Thr Tyr Gln Tyr Glu Lys 370 375 380 Asp Arg Ile Thr Ile Thr Asp Ser Leu Asn Arg Arg Glu Val Leu His 385 390 395 400 Thr Gln Gly Glu Gly Gly Leu Lys Arg Val Val Lys Lys Glu His Ala 405 410 415 Asp Gly Ser Val Thr Gln Ser Gln Phe Asp Ala Val Gly Arg Leu Arg 420 425 430 Ala Gln Thr Asp Ala Ala Gly Arg Thr Thr Glu Tyr Ser Pro Asp Val 435 440 445 Val Thr Gly Leu Ile Thr Arg Ile Thr Thr Pro Asp Gly Arg Ala Ser 450 455 460 Ala Phe Tyr Tyr Asn His His Ser Gln Leu Thr Ser Ala Thr Gly Pro 465 470 475 480 Asp Gly Leu Glu Ile Arg Arg Glu Tyr Asp Glu Trp Gly Arg Leu Ile 485 490 495 Gln Glu Thr Ala Pro Asp Gly Asp Ile Thr Arg Tyr Arg Tyr Asp Asn 500 505 510 Pro His Ser Asp Leu Pro Cys Ala Thr Glu Asp Ala Thr Gly Ser Arg 515 520 525 Lys Thr Met Thr Trp Ser Arg Tyr Gly Gln Leu Leu Ser Phe Thr Asp 530 535 540 Cys Ser Gly Tyr Val Thr Arg Tyr Asp His Asp Arg Phe Gly Gln Met 545 550 555 560 Thr Ala Val His Arg Glu Glu Gly Leu Ser Gln Tyr Arg Ala Tyr Asp 565 570 575 Ser Arg Gly Gln Leu Ile Ala Val Lys Asp Thr Gln Gly His Glu Thr 580 585 590 Arg Tyr Glu Tyr Asn Ala Ala Gly Asp Leu Thr Thr Val Ile Ala Pro 595 600 605 Asp Gly Ser Arg Asn Gly Thr Gln Tyr Asp Ala Trp Gly Lys Ala Ile 610 615 620 Cys Thr Thr Gln Gly Gly Leu Thr Arg Ser Met Glu Tyr Asp Ala Ala 625 630 635 640 Gly Arg Val Ile Arg Leu Thr Ser Glu Asn Gly Ser His Thr Thr Phe 645 650 655 Arg Tyr Asp Val Leu Asp Arg Leu Ile Gln Glu Thr Gly Phe Asp Gly 660 665 670 Arg Thr Gln Arg Tyr His His Asp Leu Thr Gly Lys Leu Ile Arg Ser 675 680 685 Glu Asp Glu Gly Leu Val Thr His Trp His Tyr Asp Glu Ala Asp Arg 690 695 700 Leu Thr His Arg Thr Val Lys Gly Glu Thr Ala Glu Arg Trp Gln Tyr 705 710 715 720 Asp Glu Arg Gly Trp Leu Thr Asp Ile Ser His Ile Ser Glu Gly His 725 730 735 Arg Val Thr Val His Tyr Gly Tyr Asp Glu Lys Gly Arg Leu Thr Gly 740 745 750 Glu Arg Gln Thr Val His His Pro Gln Thr Glu Ala Leu Leu Trp Gln 755 760 765 His Glu Thr Arg His Ala Tyr Asn Ala Gln Gly Leu Ala Asn Arg Cys 770 775 780 Ile Pro Asp Ser Leu Pro Ala Val Glu Trp Leu Thr Tyr Gly Ser Gly 785 790 795 800 Trp Leu Ala Gly Met Lys Leu Gly Asp Thr Pro Leu Val Asp Phe Thr 805 810 815 Arg Asp Arg Leu His Arg Lys Thr Leu Arg Arg Phe Gly Arg Tyr Glu 820 825 830 Leu Thr Thr Ala Tyr Thr Pro Ala Gly Gln Leu Gln Ser Gln His Leu 835 840 845 Asn Ser Leu Gln Tyr Asp Arg Asp Tyr Thr Trp Asn Asp Asn Gly Glu 850 855 860 Leu Ile Arg Ile Ser Ser Pro Arg Gln Thr Arg Ser Tyr Ser Tyr Ser 865 870 875 880 Asp Ser Gly Arg Leu Thr Gly Val His Thr Thr Ala Ala Asn Leu Asp 885 890 895 Ile Arg Ile Pro Tyr Ala Thr Asp Pro Ala Gly Asn Arg Leu Pro Asp 900 905 910 Pro Glu Leu His Pro Asp Ser Thr Leu Ser Met Trp Pro Asp Asn Arg 915 920 925 Ile Ala Arg Asp Ala His Tyr Leu Tyr Arg Tyr Asp Arg His Gly Arg 930 935 940 Leu Thr Glu Lys Thr Asp Leu Ile Pro Glu Gly Val Ile Arg Thr Asp 945 950 955 960 Asp Glu Arg Thr His Arg Tyr His Tyr Asp Ser Gln His Arg Leu Val 965 970 975 His Tyr Thr Arg Thr Gln Tyr Glu Glu Pro Leu Val Glu Ser Arg Tyr 980 985 990 Leu Tyr Asp Pro Leu Gly Arg Arg Val Ala Lys Arg Val Trp Arg Arg 995 1000 1005 Glu Arg Asp Leu Thr Gly Trp Met Ser Leu Ser Arg Lys Pro Gln Val 1010 1015 1020 Thr Trp Tyr Gly Trp Asp Gly Asp Arg Leu Thr Thr Ile Gln Asn Asp 1025 1030 1035 1040 Arg Thr Arg Ile Gln Thr Ile Tyr Gln Pro Gly Ser Phe Thr Pro Leu 1045 1050 1055 Ile Arg Val Glu Thr Ala Thr Gly Glu Leu Ala Lys Thr Gln Arg Arg 1060 1065 1070 Ser Leu Ala Asp Ala Leu Gln Gln Ser Gly Gly Glu Asp Gly Gly Ser 1075 1080 1085 Val Val Phe Pro Pro Val Leu Val Gln Met Leu Asp Arg Leu Glu Ser 1090 1095 1100 Glu Ile Leu Ala Asp Arg Val Ser Glu Glu Ser Arg Arg Trp Leu Ala 1105 1110 1115 1120 Ser Cys Gly Leu Thr Val Ala Gln Met Gln Ser Gln Met Asp Pro Val 1125 1130 1135 Tyr Thr Pro Ala Arg Lys Ile His Leu Tyr His Cys Asp His Arg Gly 1140 1145 1150 Leu Pro Leu Ala Leu Ile Ser Lys Glu Gly Ala Thr Glu Trp Cys Ala 1155 1160 1165 Glu Tyr Asp Glu Trp Gly Asn Leu Leu Asn Glu Glu Asn Pro His Gln 1170 1175 1180 Leu Gln Gln Leu Ile Arg Leu Pro Gly Gln Gln Tyr Asp Glu Glu Ser 1185 1190 1195 1200 Gly Leu Tyr Tyr Asn Arg His Arg Tyr Tyr Asp Pro Leu Gln Gly Arg 1205 1210 1215 Tyr Ile Thr Gln Asp Pro Ile Gly Leu Lys Gly Gly Trp Asn Leu Tyr 1220 1225 1230 Thr Tyr Pro Leu Ser Pro Val Asn Gly Met Asp Pro Leu Gly Leu Tyr 1235 1240 1245 Glu Phe Lys Ser Lys Asn Ile Asp Asp Ile Gly Ile Phe Ala Leu Ala 1250 1255 1260 Met Cys Asn Gly Glu Ser Ile Asn Glu Asn Lys Glu Tyr Gly Gly Leu 1265 1270 1275 1280 Ile Cys Lys Lys Gln Gly Glu Tyr Phe Pro Met Asn Pro Ile Ser Ser 1285 1290 1295 Asn Asp Asn Asp Ser Val Asp Leu Arg Asn Ile Lys Cys Pro Glu Gly 1300 1305 1310 Ser Glu Arg Val Gly Asp Tyr His Thr His Gly Phe Tyr Ser Asp Asp 1315 1320 1325 Lys Gly Asn Lys Val Thr Lys Glu Asn Asp Val Tyr Asp Ser Leu Asn 1330 1335 1340 Phe Ser Ser Lys Asp Leu Thr Asn Ser Tyr Met Asn Gly Met Gly Lys 1345 1350 1355 1360 Lys Glu Cys Ser Ser Tyr Leu Gly Thr Pro Asn Asn Thr Tyr Leu Lys 1365 1370 1375 Tyr Asn Pro Lys Ala Lys Gly Asn Gly Val Thr Ile Ile Arg Gln Gly 1380 1385 1390 Ser Asn * <210> 1473 <211> 5359 <212> DNA <213> Escherichia coli O157:H7 <400> 1473 ggtaatcaat aaaagccgga aaattggcaa ttaaccgaag aagccctctc cggctggaaa 60 gggcaatagg ctaaatcagt tgtagttaat tttgaaaagt accactgtat caaagggacc 120 aacgtcgatg ggcgtacccg gcgtggatga caattctgcc gtgtaggttt tttcatacac 180 taacaggtcg ctggtaaaat cggcatactc actgtatttg ttgaaagtat agggtgaggc 240 attttcatcc aacaatcgaa gcttcaagcc attgccaatg agcagtgatt tatcttcgtc 300 gataagggtt tcatcggtat aaaacgaaga gctgacttta aaaccgtcgg tacactggtc 360 gttttgtgat ttggttgtag ttattttaaa ttgctgcgac atcgtatggc gacgaatatc 420 cagcacgtta aatcggccaa aatcaacgac ctgggtttca ggtgagatag caaagttgac 480 gctgcaatcc agcacgcgga tattttccag accggtaatg tgatatttca gattcttcgc 540 ggtagggtct tcgttcacgc tgcctgcgcc atcaaactgt acgacgatgt aatcgctgag 600 tttgctctga taatcatggg gcggcatggc gcgaacttta acgtaaagcc gcatacgcgc 660 cacaaacgtc cgcgatttgt gcataacggt tggatcgccg gagcaaagtt tattttgcca 720 gcccatcgca atgatctgct ccggggtgta aatatcaata ttcttactgt cgatgcactg 780 attcgtgtcg atgcggcttt tcccaaggct tgcgtcatag tccacgcctt cataggttac 840 gcccaattga taatagggat cctgaatacc ggggtaaggg tttacccagg cgtagacgtg 900 ctcgctttca aaattaccgt ttgtgttgtt gtcacagtag accggaattt ttatatcgtc 960 agattcccag attttatcgc cgggtttgga attggccgga acggcgaagg gcataatagc 1020 ttccgatttt tctacagcgc cgtttgcggt accaaaatag cagttcagcg ccagcgccgc 1080 ttttagcggc aaaaaaatca gacagatggc gagcaacacg cctttggcga atctcatttt 1140 ttattctcca ccggctgcag gcggcattgc cgctggcagg agagcgtgtt catacgcaat 1200 gcgccgtagt cgtccatgta gccaagataa aactgcttgc cgctatagct gcccgtgctg 1260 gtggtgaccg aactgaacgg tgcgaccatc gtgcttttaa agccaggcag cacgcctttc 1320 tcatcccgcc caagataggc aatagtcaga tagtatccgg tcggggtttt cagggtaagc 1380 tggttattct gctggctaac ctgtagctgt tgctcaacat gatcgcccat ttttttgcgt 1440 aatgcggcgg gtcgccagaa tagcttaatg cgactttgga cggcgacttg caggatcgca 1500 tggccctcgc tgccttccgg gacaggcgga atttcacgca ggttatagta aaagagagat 1560 tcgcgatcgg tgggtaattt cgcggtggcg gcttgtttca tgatccgaac ctgcgaagtc 1620 gcttttggct ccagtcgctg gataggcggc agggcgacga gaaattcatc gcttttctct 1680 cccttttcat tttctatcca tgaataggcg aggtagggga gtttatcgct gcggttttcc 1740 acgcgcaggc tggttgcttt atctttgcta ttaaagatga tgcgcgtgcg gtcaggctgc 1800 actgcgccgt ggctgcacat actggcaacc agaagaatca aagggaatcc tttaacaaat 1860 gtcatcgtct tttccttaat taatgacagg gtaaaatcag gcgcttagtc acatcttcca 1920 gatgttccgg cagatgaatg gcacacgttt tctggtcgcc ccagtgcacg gtaaattgtt 1980 gattttcatc gaccccactc agccatgcgt gaccgttttc gccaaccatc ccgacgctga 2040 caccgccttc agcctggcga acatcggcac cgagcggcgg gaaatgcccg ttagcatcgc 2100 tgataatgac gttgagatct ttcccggcgc gggacgccag cgatttaaag ccgatggcgc 2160 cttcggtcta ggtttctttc accacgtttt cggaaacggt aacgccgtca ggcaagtcgt 2220 tcatattgac cgccaccgtc gtaggctggt agctggaaac aaacggtacc acggcaatac 2280 caaagcggtt ggtgtagtca atattgccct gaatcggaat atcgcccacg ccgtcggtgc 2340 tgaccatcag gcgtggttca ttggtggaac tgcggcgatg gaatgccgcg ccatgttgag 2400 tcgcggtaaa cgagccgctc caactggcac tggcggaagt gtaatcattg gcggcatagg 2460 ttccggtcag atcccattcc cccgccgaac tgaggtgttg gtaattgccg ctgacctgcg 2520 caccgttatc cgggcgatcg gattgtattc cagccgacat tccccaactg tttcgttcat 2580 ccagggtatc gttccacgac atgcggtggg tggtagtatt actgttgttc tgcatgtcat 2640 aacccagtcg accactttcc ccaatcggta aggagatcga aaagtaaatc tggttgtcgc 2700 gatctttatc ttcataatgg gtggtgttga acgaggtcga gacagaaata tctttccagt 2760 cgccaatgtc gacgttaaaa ccgacggtaa tgttggccgt ggtggaggta tccgcattcc 2820 accagctctg atgcaggatg ttggcgtaga gattaagatt cagcagagta ataggctgac 2880 cgaaggagag gctgattgtt tgcttttcat cctgcgcgtc ggcgtcattg tatttgtgat 2940 caatgtagtt agcgtagctg tgaaaatggc gatcggagaa gcgataggct gccaatgaga 3000 tggtgctgtt ggtcgcatca acctgtttgc tgtagttaaa gcggtagctg taaccctgct 3060 catcctgttg ggtatcaaaa tggctgtcgg cccaggtcac gtcaaacgac agcgccccca 3120 tccagagcat attttgccca atacccagcg cgccggaacg atagtcatcg cctgcgagaa 3180 gcatgccgcc atatagtgaa gtgttggaga gcattcccca ggagacttca tggctaatga 3240 aggtttcatc ctcggtgtgg tgcgacatag aggaacgcgg gcgaccggca gccagtttat 3300 agcgcacctg gccctgacgc gtcaggaacg gggtagaggc cgctgaaacc tggaagttat 3360 tcacccgtcc atcttcttcg ctcactttga catccagtgt accttgcact gactgattca 3420 ggtcatcaat aataaatggg cctggtggaa cttttttctg gtaaatcacg cgaccagaat 3480 ggcttatcgt gaccgtggcg ttagtctgtg cgatgccgct gatttgcggc gcgtagccgc 3540 gtaactccca ggggagcatt cgatcgtcgc tggctaacgc cgcaccggta taggagaaac 3600 catcaaaaat gttagagcta aaatcggttt cgcccagggt taatcgggaa cctatttgcg 3660 gtaacgggcg gaacaggtag gtccgtgaaa tcgccccaga ttgttcacgg ttgtcgccgc 3720 tatcggactg gctaagctga taatcgctgc gcagacgcca tgccccggcg ttgaggcccg 3780 tggtgccata ggcgttcagg ttgttgctgc tgctgccgct ttgtgggcga taagtgctgg 3840 caaacaggtt gtaatccatc aggaagccag gaataccgtt attccacgtt gagggtggcg 3900 tccagttttc tgaatgccac gccagccatg cctgcgggat tgtaatattg agctgttgat 3960 ttgcctgatc gaaagtaaag atgatttcag ggaagacact aaaatcgaca cattctttta 4020 ttgccggtaa ttttttacga aagtcagatt taagtccgaa gagttcgatc agcgattcat 4080 tgatacaagg aataatttta tcgccagatt tttgccagcg aatttgttgc ccattactga 4140 ttttattatt attaaccgta acactaacaa agtaatcgcc gggagctacg acgccttttt 4200 gattgagcaa cgaaatatca acgctatccc gaatcgactt atcgagaacg ttaaggttaa 4260 attcagctgt cagcgcagga ggggttacca ttgccagaca ggaaagaaca gagagtcgat 4320 aaatattcac ggcatccata cctgaacaat attcgcaaaa ggcggctaat cagccgcctt 4380 aaaaaggatt attggtaatc cagaacgtaa gttgcgttag cagtaacggc ccccgcggta 4440 accgaaactg cgttatccat ctgttccatc caggcaaaga agtttaacgt ttgttctgtt 4500 gaacttgcca ataagtcaat tgttggcgct tctgttccca atgtaacaaa tgattcatct 4560 ttgttcatga gacgtacgcc aacgccggta gcctcgccag cactgatgtt actaaggagc 4620 ggggttgcac ctgtcgtttt agccgtgctg tcgaaggtca cgcctacctt tgagaccacg 4680 ccacccttgc catcatccca gcctgcaata tcacagttga ttaagcgaat attgacaggt 4740 tttttctcgc tatgatgttc tcgatttatg tgggatgtgg ttacttcacc caggtcaatg 4800 ttcatatcaa ggtcatcagg gtgaatttca catggtgctt caataacttc acctttaaag 4860 tggatttcac cagatccttc atctgcagca aaaacaggtg aagcgaatag tagagatatg 4920 gccagggcgg ccagtgtttt ttgtccttta aacatacatg aatccttcat gggctatgat 4980 aaagtatact aattattccg acagaatagt ggttttttgt tcatgtaata atattaatgt 5040 tgctacatta tgtttgagag tttctcaaag ctctcgaatc ataaataaag tgaattaatc 5100 ctattacgag tttatttaat tgtgggtgct acccaatgta ttctacatcg attggcggga 5160 taacggtggt ggtgaatgaa aaattaggat tttatttagt tatcggatat gtattcttgt 5220 aacgtgtaat tatgtatttg tgtccgatta cgtttttttg tcgatagaca taactaacga 5280 acaaaaaaaa gcccgccaga tattcaggcg ggctaaacga tatatggttc aaatcagata 5340 attaatgttt aacatctga 5359 <210> 1474 <211> 354 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(76..1137) <400> 1474 Met Arg Phe Ala Lys Gly Val Leu Leu Ala Ile Cys Leu Ile Phe Leu 1 5 10 15 Pro Leu Lys Ala Ala Leu Ala Leu Asn Cys Tyr Phe Gly Thr Ala Asn 20 25 30 Gly Ala Val Glu Lys Ser Glu Ala Ile Met Pro Phe Ala Val Pro Ala 35 40 45 Asn Ser Lys Pro Gly Asp Lys Ile Trp Glu Ser Asp Asp Ile Lys Ile 50 55 60 Pro Val Tyr Cys Asp Asn Asn Thr Asn Gly Asn Phe Glu Ser Glu His 65 70 75 80 Val Tyr Ala Trp Val Asn Pro Tyr Pro Gly Ile Gln Asp Pro Tyr Tyr 85 90 95 Gln Leu Gly Val Thr Tyr Glu Gly Val Asp Tyr Asp Ala Ser Leu Gly 100 105 110 Lys Ser Arg Ile Asp Thr Asn Gln Cys Ile Asp Ser Lys Asn Ile Asp 115 120 125 Ile Tyr Thr Pro Glu Gln Ile Ile Ala Met Gly Trp Gln Asn Lys Leu 130 135 140 Cys Ser Gly Asp Pro Thr Val Met His Lys Ser Arg Thr Phe Val Ala 145 150 155 160 Arg Met Arg Leu Tyr Val Lys Val Arg Ala Met Pro Pro His Asp Tyr 165 170 175 Gln Ser Lys Leu Ser Asp Tyr Ile Val Val Gln Phe Asp Gly Ala Gly 180 185 190 Ser Val Asn Glu Asp Pro Thr Ala Lys Asn Leu Lys Tyr His Ile Thr 195 200 205 Gly Leu Glu Asn Ile Arg Val Leu Asp Cys Ser Val Asn Phe Ala Ile 210 215 220 Ser Pro Glu Thr Gln Val Val Asp Phe Gly Arg Phe Asn Val Leu Asp 225 230 235 240 Ile Arg Arg His Thr Met Ser Gln Gln Phe Lys Ile Thr Thr Thr Lys 245 250 255 Ser Gln Asn Asp Gln Cys Thr Asp Gly Phe Lys Val Ser Ser Ser Phe 260 265 270 Tyr Thr Asp Glu Thr Leu Ile Asp Glu Asp Lys Ser Leu Leu Ile Gly 275 280 285 Asn Gly Leu Lys Leu Arg Leu Leu Asp Glu Asn Ala Ser Pro Tyr Thr 290 295 300 Phe Asn Lys Tyr Ser Glu Tyr Ala Asp Phe Thr Ser Asp Leu Leu Val 305 310 315 320 Tyr Glu Lys Thr Tyr Thr Ala Glu Leu Ser Ser Thr Pro Gly Thr Pro 325 330 335 Ile Asp Val Gly Pro Phe Asp Thr Val Val Leu Phe Lys Ile Asn Tyr 340 345 350 Asn * <210> 1475 <211> 244 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1134..1865) <400> 1475 Met Thr Phe Val Lys Gly Phe Pro Leu Ile Leu Leu Val Ala Ser Met 1 5 10 15 Cys Ser His Gly Ala Val Gln Pro Asp Arg Thr Arg Ile Ile Phe Asn 20 25 30 Ser Lys Asp Lys Ala Thr Ser Leu Arg Val Glu Asn Arg Ser Asp Lys 35 40 45 Leu Pro Tyr Leu Ala Tyr Ser Trp Ile Glu Asn Glu Lys Gly Glu Lys 50 55 60 Ser Asp Glu Phe Leu Val Ala Leu Pro Pro Ile Gln Arg Leu Glu Pro 65 70 75 80 Lys Ala Thr Ser Gln Val Arg Ile Met Lys Gln Ala Ala Thr Ala Lys 85 90 95 Leu Pro Thr Asp Arg Glu Ser Leu Phe Tyr Tyr Asn Leu Arg Glu Ile 100 105 110 Pro Pro Val Pro Glu Gly Ser Glu Gly His Ala Ile Leu Gln Val Ala 115 120 125 Val Gln Ser Arg Ile Lys Leu Phe Trp Arg Pro Ala Ala Leu Arg Lys 130 135 140 Lys Met Gly Asp His Val Glu Gln Gln Leu Gln Val Ser Gln Gln Asn 145 150 155 160 Asn Gln Leu Thr Leu Lys Thr Pro Thr Gly Tyr Tyr Leu Thr Ile Ala 165 170 175 Tyr Leu Gly Arg Asp Glu Lys Gly Val Leu Pro Gly Phe Lys Ser Thr 180 185 190 Met Val Ala Pro Phe Ser Ser Val Thr Thr Ser Thr Gly Ser Tyr Ser 195 200 205 Gly Lys Gln Phe Tyr Leu Gly Tyr Met Asp Asp Tyr Gly Ala Leu Arg 210 215 220 Met Asn Thr Leu Ser Cys Gln Arg Gln Cys Arg Leu Gln Pro Val Glu 225 230 235 240 Asn Lys Lys * <210> 1476 <211> 724 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2168..4339) <400> 1476 Met Asp Ala Val Asn Ile Tyr Arg Leu Ser Val Leu Ser Cys Leu Ala 1 5 10 15 Met Val Thr Pro Pro Ala Leu Thr Ala Glu Phe Asn Leu Asn Val Leu 20 25 30 Asp Lys Ser Ile Arg Asp Ser Val Asp Ile Ser Leu Leu Asn Gln Lys 35 40 45 Gly Val Val Ala Pro Gly Asp Tyr Phe Val Ser Val Thr Val Asn Asn 50 55 60 Asn Lys Ile Ser Asn Gly Gln Gln Ile Arg Trp Gln Lys Ser Gly Asp 65 70 75 80 Lys Ile Ile Pro Cys Ile Asn Glu Ser Leu Ile Glu Leu Phe Gly Leu 85 90 95 Lys Ser Asp Phe Arg Lys Lys Leu Pro Ala Ile Lys Glu Cys Val Asp 100 105 110 Phe Ser Val Phe Pro Glu Ile Ile Phe Thr Phe Asp Gln Ala Asn Gln 115 120 125 Gln Leu Asn Ile Thr Ile Pro Gln Ala Trp Leu Ala Trp His Ser Glu 130 135 140 Asn Trp Thr Pro Pro Ser Thr Trp Asn Asn Gly Ile Pro Gly Phe Leu 145 150 155 160 Met Asp Tyr Asn Leu Phe Ala Ser Thr Tyr Arg Pro Gln Ser Gly Ser 165 170 175 Ser Ser Asn Asn Leu Asn Ala Tyr Gly Thr Thr Gly Leu Asn Ala Gly 180 185 190 Ala Trp Arg Leu Arg Ser Asp Tyr Gln Leu Ser Gln Ser Asp Ser Gly 195 200 205 Asp Asn Arg Glu Gln Ser Gly Ala Ile Ser Arg Thr Tyr Leu Phe Arg 210 215 220 Pro Leu Pro Gln Ile Gly Ser Arg Leu Thr Leu Gly Glu Thr Asp Phe 225 230 235 240 Ser Ser Asn Ile Phe Asp Gly Phe Ser Tyr Thr Gly Ala Ala Leu Ala 245 250 255 Ser Asp Asp Arg Met Leu Pro Trp Glu Leu Arg Gly Tyr Ala Pro Gln 260 265 270 Ile Ser Gly Ile Ala Gln Thr Asn Ala Thr Val Thr Ile Ser His Ser 275 280 285 Gly Arg Val Ile Tyr Gln Lys Lys Val Pro Pro Gly Pro Phe Ile Ile 290 295 300 Asp Asp Leu Asn Gln Ser Val Gln Gly Thr Leu Asp Val Lys Val Ser 305 310 315 320 Glu Glu Asp Gly Arg Val Asn Asn Phe Gln Val Ser Ala Ala Ser Thr 325 330 335 Pro Phe Leu Thr Arg Gln Gly Gln Val Arg Tyr Lys Leu Ala Ala Gly 340 345 350 Arg Pro Arg Ser Ser Met Ser His His Thr Glu Asp Glu Thr Phe Ile 355 360 365 Ser His Glu Val Ser Trp Gly Met Leu Ser Asn Thr Ser Leu Tyr Gly 370 375 380 Gly Met Leu Leu Ala Gly Asp Asp Tyr Arg Ser Gly Ala Leu Gly Ile 385 390 395 400 Gly Gln Asn Met Leu Trp Met Gly Ala Leu Ser Phe Asp Val Thr Trp 405 410 415 Ala Asp Ser His Phe Asp Thr Gln Gln Asp Glu Gln Gly Tyr Ser Tyr 420 425 430 Arg Phe Asn Tyr Ser Lys Gln Val Asp Ala Thr Asn Ser Thr Ile Ser 435 440 445 Leu Ala Ala Tyr Arg Phe Ser Asp Arg His Phe His Ser Tyr Ala Asn 450 455 460 Tyr Ile Asp His Lys Tyr Asn Asp Ala Asp Ala Gln Asp Glu Lys Gln 465 470 475 480 Thr Ile Ser Leu Ser Phe Gly Gln Pro Ile Thr Leu Leu Asn Leu Asn 485 490 495 Leu Tyr Ala Asn Ile Leu His Gln Ser Trp Trp Asn Ala Asp Thr Ser 500 505 510 Thr Thr Ala Asn Ile Thr Val Gly Phe Asn Val Asp Ile Gly Asp Trp 515 520 525 Lys Asp Ile Ser Val Ser Thr Ser Phe Asn Thr Thr His Tyr Glu Asp 530 535 540 Lys Asp Arg Asp Asn Gln Ile Tyr Phe Ser Ile Ser Leu Pro Ile Gly 545 550 555 560 Glu Ser Gly Arg Leu Gly Tyr Asp Met Gln Asn Asn Ser Asn Thr Thr 565 570 575 Thr His Arg Met Ser Trp Asn Asp Thr Leu Asp Glu Arg Asn Ser Trp 580 585 590 Gly Met Ser Ala Gly Ile Gln Ser Asp Arg Pro Asp Asn Gly Ala Gln 595 600 605 Val Ser Gly Asn Tyr Gln His Leu Ser Ser Ala Gly Glu Trp Asp Leu 610 615 620 Thr Gly Thr Tyr Ala Ala Asn Asp Tyr Thr Ser Ala Ser Ala Ser Trp 625 630 635 640 Ser Gly Ser Phe Thr Ala Thr Gln His Gly Ala Ala Phe His Arg Arg 645 650 655 Ser Ser Thr Asn Glu Pro Arg Leu Met Val Ser Thr Asp Gly Val Gly 660 665 670 Asp Ile Pro Ile Gln Gly Asn Ile Asp Tyr Thr Asn Arg Phe Gly Ile 675 680 685 Ala Val Val Pro Phe Val Ser Ser Tyr Gln Pro Thr Thr Val Ala Val 690 695 700 Asn Met Asn Asp Leu Pro Asp Gly Val Thr Val Ser Glu Asn Val Val 705 710 715 720 Lys Glu Thr * <210> 1477 <211> 194 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4389..4970) <400> 1477 Met Lys Asp Ser Cys Met Phe Lys Gly Gln Lys Thr Leu Ala Ala Leu 1 5 10 15 Ala Ile Ser Leu Leu Phe Ala Ser Pro Val Phe Ala Ala Asp Glu Gly 20 25 30 Ser Gly Glu Ile His Phe Lys Gly Glu Val Ile Glu Ala Pro Cys Glu 35 40 45 Ile His Pro Asp Asp Leu Asp Met Asn Ile Asp Leu Gly Glu Val Thr 50 55 60 Thr Ser His Ile Asn Arg Glu His His Ser Glu Lys Lys Pro Val Asn 65 70 75 80 Ile Arg Leu Ile Asn Cys Asp Ile Ala Gly Trp Asp Asp Gly Lys Gly 85 90 95 Gly Val Val Ser Lys Val Gly Val Thr Phe Asp Ser Thr Ala Lys Thr 100 105 110 Thr Gly Ala Thr Pro Leu Leu Ser Asn Ile Ser Ala Gly Glu Ala Thr 115 120 125 Gly Val Gly Val Arg Leu Met Asn Lys Asp Glu Ser Phe Val Thr Leu 130 135 140 Gly Thr Glu Ala Pro Thr Ile Asp Leu Leu Ala Ser Ser Thr Glu Gln 145 150 155 160 Thr Leu Asn Phe Phe Ala Trp Met Glu Gln Met Asp Asn Ala Val Ser 165 170 175 Val Thr Ala Gly Ala Val Thr Ala Asn Ala Thr Tyr Val Leu Asp Tyr 180 185 190 Gln * <210> 1478 <211> 4950 <212> DNA <213> Escherichia coli O157:H7 <400> 1478 ttatagcctg caggcagcat actgctgcct gcagggggta taacagtcga caggggaacc 60 gactgcttta ttcttaccag gtcacattga taccaactac accctgtagc ggattctcaa 120 tgtcgtcacc tttggtgtag tcaaggcttg catatgctcc catgtttttg gtgatatcag 180 cctgtacacc tgcacccacg cggaatgctg caccgtcaat gctggcattg acagactcat 240 cacccagacg gagccagagc atcaacagtt gaggatcccg taacattcca gacagactcg 300 ttttgcagag atacactggc atttcctgcc cctgaaactt tgcctttcca gactgaacta 360 tcggaaagat ttatatccag attactaccc gctttatcgc cgctattgaa agtataagca 420 ttaccttccc agtaagagcg ggcaacgttc atgtttacat ttgttgtggt agcggctgaa 480 ttctcgcttt cagaaagggc caggacatca gagtagatgg ttgaatcagc aacagacaaa 540 tttaaatttt gcgttgctga acctgtgcct tgtgccgaag cagaggcata aattgtttgt 600 ttattattag ccgccccaat tactgagcca tccttaatat tcaggttgac tgtatgaatt 660 cccgtcttat tcccggcagt aactattgtt tcaatccgac cattaataat atttgagcca 720 gcaagggtaa tgttgtcggt tgcatcacct tcaaaactat tcaataagct acccttttga 780 gcaaaaattg ccgtggaggc gttgctggaa ctcttattac cttgagcatt tatggttgtg 840 ccattaagcg tgacattatt tcccttggcc ccttccagag atatccctgt cgcactacct 900 ttttcatttt ttgcaacgaa attaccgcca ttaacaacaa catcgccagt tgaatcaatg 960 accattgcag tccggacata ggtgccttca ccttgagctg tgatggtgga gtctgtagca 1020 ttaatcacaa catttttgtt accactaact tttacacctt caacgaattt tttgtctgcc 1080 gttgattcag cagtaatatc atgaccagca aaagcaacat taaggtcttc atctgccgca 1140 ttaattgtta cggctgtaat ctgtttgtct gctgtattgc taataacaac atcttgatcc 1200 agagtcgtct tatctttatt cagcgtaacc gaatcagttg ataccgcgtt atcagcagcg 1260 aatgctggtg cagaaagagc cataacaata gctgtcgcta atgcgctgcg gtaaaatgcc 1320 ttactgtttt tcatgaagaa attctccatt ctggtaacta atttcaattt cccacttatt 1380 tatatttatg cagagataaa acctgcgtcc ctgcatttac caccacggaa tacctgttgg 1440 tatttccgtt ttcacgcaat gtcatggcat tcgttttttc caatgcattt ccatcaccgt 1500 gaaatttatt gctgctcagc agcagggctt cccgcaatga catgctgtcc ggtattcccc 1560 aacgcttttt tagcgactgc tcggcaagcc atatctgtct tatccccgtt ttgagaaact 1620 gcgcactgta ttcccagctg tgtccggcaa gaagcaacga caacaccttc ttttgctttt 1680 ccgggaagcg ttctgacatg acgattgtct ttgtgcggtt attcacctct ttcataaaga 1740 cagagtaact gtccataact ggcaaatttt ctgcatgttt cagccctgat aacccaccag 1800 aggaatttgc aatactgatg acatgctcta ctgacattcc tggtttcagt aacctcaggt 1860 ttttgagaac gccagaaata ctcacatccg gtggcagaaa aaatggcgcg acgcacaaca 1920 ccaccacgaa tgagtgatcc cgataaaatc ggaaccacat ttcagcgcat tcggcaggtc 1980 gccctgccga tatcacgaca ctctgtggcc tgtgccgcaa tttattgcgt aactcctctt 2040 ctgttccgat gcaggtaaca ttgccgacag aaccggttga tagagctgcg aactgcgctg 2100 gtacaattcc tgagggacag aaaagaacga aacgcatcct tccctcacag atgtcagtac 2160 gccagcacgc tgtacaggct gtacagcgtg cctcccaatc ctgcagccca gagcagtaga 2220 aatattttgg cccctacact gtagcgagtc cgtacgcgcc gcagtggggg gtagtaacaa 2280 cgctgttgtg tcataacaat cctggtcttt ttttagaaat attttttctt tgtccgggaa 2340 gtacttttcc ggaaatggcg tcagaattta ttgattcacc aacggcaact ttctctggat 2400 aaagaattcc ggataccatg ttctgcacat actgagtgag tcgatgagcg gaatgttgtc 2460 cgacatatct tgcatgtagc cgtatattcc gtttcactct gctgtcaccg catcccgtat 2520 agagcagcct gaaatcgctc agagttccca gtccaagttt cattaatgcc cgtgtggcaa 2580 tcgcatgcag ggtctttgaa ctgcgttgtt cataacgggc aatctcactg aaactcatgc 2640 cctgcatcag aatcttaagc acgctcaact cccgtgcagt caggagccag aaatcgctca 2700 tatcgccggg caaaggacgt agtaaccagc ggataatttg attctgataa cgactcgctg 2760 tcagcatggt gccgatgcgt gggaagccgt tatacagact tgcagcagga gcattatcga 2820 accagtcgga gtcaccggtc aggcagacct gccattgccc ggcatcactc cgcaagcgga 2880 caagacaagc cagaagaact aactcccccg aaggaagcta agggatatca gccaacagat 2940 agccacagga ggtctttaaa acgaattcaa cctctgtagt gacgttgctg tacacccgca 3000 cgatatacct gtccgctggg atgagagact ccagtgccag cctggtaaac tgacaggcac 3060 tgataataac cagaggcttc ttcattcaga ctcgtccacg ccatagctac aaaacctgac 3120 attttgattc aaaatgtcag gttttgttta attgcctgaa tatttaattt tcttggaata 3180 taaatctaat ttgtttgatt tttattgttt ttaatttggt tgcatttaac aacatgagtg 3240 aaagttaatc actggtatga ccttggcggt taatcatttc aaatcatggg gttattttac 3300 tttagcgaga aatatcaaca tgttatgtgt tttattgaat tgaatgggct gtttttttat 3360 ggaagaattg aggaaaacgt aggaatctga cattttgaat cagaaggtac tgttttaacg 3420 aggctttttt ttccacaccc ctttaaatcg agcagcatta ctggctgtgt atctgacagt 3480 atgctggata tttcgatgac ccagataatc ctgaagtagt cgggtatcga caccattgtc 3540 agccagagca aaaccacagg catgacgtaa catatgagga tgtgctttta cagctaatcc 3600 tgcacgtctt ccagcctcac gaatgataga aaaaaatgtt gtctgctgat agggcggcgt 3660 ttccgggaga gaaaaagcca gtctccttca actccgtttt caattaactt cctctgctta 3720 agccacaact tgatcaaatt atattcatca ggaagaagag gatgtgttgt cgagaaacca 3780 tttttaatcc gccgaatatt aagttgtttt cctgatgcat caatatcgga taaacgtaaa 3840 tcaagaagtt cactggccct aaaaccgtga atgaaagcca tcataattag acagcgattt 3900 ctttcaggaa aggacatgct ctgggctgca tccatcagcc tgtagacttc atcctgtgtg 3960 agatattttc tcgtcatacg ccaccgtgta cagttgtaaa aaagagaggc acacccagat 4020 aagtatgcct gcaatcagaa cgttatcgat gtaatctcat tatctcatta ataagatttt 4080 ttgaatagta gttctacgca atagactaaa tatgaactat ttattgtgct gcttttctac 4140 aagccatttt taatgcgtgt ttttatctac attgatgtga aaaaataaat ataaaagcta 4200 tgaattacag ggcgtggggg atgtgtgtta cgtctaatgt tttagtgatg tttagtagtt 4260 ttgagatatt tgatgttatt tcttataagg ttgtttttat tgtttatctt attgatttta 4320 tatgcatttt gtcgttcaat gaagttattg tgtagaaaat aaaaatttaa tattattccc 4380 gttaatttac aataacacat tgttgtaaga tattttttag tcgtaagtaa atcattattg 4440 atgggttctg ctaataaatt aaagattttc tcttaaatag ttttttttgc ttttttgtaa 4500 atatcaattt gtttattttt gattcatttg ctggagagta tttcaacaat ttttattttt 4560 ttgcataaac ttattaacag ctttttattg tcaattggaa atcaatgtaa actaaaatgt 4620 tagcgaatcg ataaccttgt actaaaaaat atttaagcat gatgattaat taaagaagag 4680 taaaaataaa tcactgctaa taaattatac gaattgtgtt taaagctcca cgttgttttg 4740 gtctgactta tttttgtcct cgttacaaga acccttttcg tatatgctaa ccgtgagcgg 4800 gagtgaacaa gtcaccatag ccaggaacac tagcggcgta attcttaagc tgagtggcat 4860 ttcacctgcg gtttatcagt gcattcatag taccttcatc agcgagattg aacgagtcag 4920 cttagaattt gctggcgagg ttgtcactat 4950 <210> 1479 <211> 83 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(74..322) <400> 1479 Met Pro Val Tyr Leu Cys Lys Thr Ser Leu Ser Gly Met Leu Arg Asp 1 5 10 15 Pro Gln Leu Leu Met Leu Trp Leu Arg Leu Gly Asp Glu Ser Val Asn 20 25 30 Ala Ser Ile Asp Gly Ala Ala Phe Arg Val Gly Ala Gly Val Gln Ala 35 40 45 Asp Ile Thr Lys Asn Met Gly Ala Tyr Ala Ser Leu Asp Tyr Thr Lys 50 55 60 Gly Asp Asp Ile Glu Asn Pro Leu Gln Gly Val Val Gly Ile Asn Val 65 70 75 80 Thr Trp * <210> 1480 <211> 365 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(240..1334) <400> 1480 Met Lys Asn Ser Lys Ala Phe Tyr Arg Ser Ala Leu Ala Thr Ala Ile 1 5 10 15 Val Met Ala Leu Ser Ala Pro Ala Phe Ala Ala Asp Asn Ala Val Ser 20 25 30 Thr Asp Ser Val Thr Leu Asn Lys Asp Lys Thr Thr Leu Asp Gln Asp 35 40 45 Val Val Ile Ser Asn Thr Ala Asp Lys Gln Ile Thr Ala Val Thr Ile 50 55 60 Asn Ala Ala Asp Glu Asp Leu Asn Val Ala Phe Ala Gly His Asp Ile 65 70 75 80 Thr Ala Glu Ser Thr Ala Asp Lys Lys Phe Val Glu Gly Val Lys Val 85 90 95 Ser Gly Asn Lys Asn Val Val Ile Asn Ala Thr Asp Ser Thr Ile Thr 100 105 110 Ala Gln Gly Glu Gly Thr Tyr Val Arg Thr Ala Met Val Ile Asp Ser 115 120 125 Thr Gly Asp Val Val Val Asn Gly Gly Asn Phe Val Ala Lys Asn Glu 130 135 140 Lys Gly Ser Ala Thr Gly Ile Ser Leu Glu Gly Ala Lys Gly Asn Asn 145 150 155 160 Val Thr Leu Asn Gly Thr Thr Ile Asn Ala Gln Gly Asn Lys Ser Ser 165 170 175 Ser Asn Ala Ser Thr Ala Ile Phe Ala Gln Lys Gly Ser Leu Leu Asn 180 185 190 Ser Phe Glu Gly Asp Ala Thr Asp Asn Ile Thr Leu Ala Gly Ser Asn 195 200 205 Ile Ile Asn Gly Arg Ile Glu Thr Ile Val Thr Ala Gly Asn Lys Thr 210 215 220 Gly Ile His Thr Val Asn Leu Asn Ile Lys Asp Gly Ser Val Ile Gly 225 230 235 240 Ala Ala Asn Asn Lys Gln Thr Ile Tyr Ala Ser Ala Ser Ala Gln Gly 245 250 255 Thr Gly Ser Ala Thr Gln Asn Leu Asn Leu Ser Val Ala Asp Ser Thr 260 265 270 Ile Tyr Ser Asp Val Leu Ala Leu Ser Glu Ser Glu Asn Ser Ala Ala 275 280 285 Thr Thr Thr Asn Val Asn Met Asn Val Ala Arg Ser Tyr Trp Glu Gly 290 295 300 Asn Ala Tyr Thr Phe Asn Ser Gly Asp Lys Ala Gly Ser Asn Leu Asp 305 310 315 320 Ile Asn Leu Ser Asp Ser Ser Val Trp Lys Gly Lys Val Ser Gly Ala 325 330 335 Gly Asn Ala Ser Val Ser Leu Gln Asn Glu Ser Val Trp Asn Val Thr 340 345 350 Gly Ser Ser Thr Val Asp Ala Leu Ala Pro Ser Gly * 355 360 <210> 1481 <211> 254 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1376..2137) <400> 1481 Met Arg Phe Val Leu Phe Cys Pro Ser Gly Ile Val Pro Ala Gln Phe 1 5 10 15 Ala Ala Leu Ser Thr Gly Ser Val Gly Asn Val Thr Cys Ile Gly Thr 20 25 30 Glu Glu Glu Leu Arg Asn Lys Leu Arg His Arg Pro Gln Ser Val Val 35 40 45 Ile Ser Ala Gly Arg Pro Ala Glu Cys Ala Glu Met Trp Phe Arg Phe 50 55 60 Tyr Arg Asp His Ser Phe Val Val Val Leu Cys Val Ala Pro Phe Phe 65 70 75 80 Leu Pro Pro Asp Val Ser Ile Ser Gly Val Leu Lys Asn Leu Arg Leu 85 90 95 Leu Lys Pro Gly Met Ser Val Glu His Val Ile Ser Ile Ala Asn Ser 100 105 110 Ser Gly Gly Leu Ser Gly Leu Lys His Ala Glu Asn Leu Pro Val Met 115 120 125 Asp Ser Tyr Ser Val Phe Met Lys Glu Val Asn Asn Arg Thr Lys Thr 130 135 140 Ile Val Met Ser Glu Arg Phe Pro Glu Lys Gln Lys Lys Val Leu Ser 145 150 155 160 Leu Leu Leu Ala Gly His Ser Trp Glu Tyr Ser Ala Gln Phe Leu Lys 165 170 175 Thr Gly Ile Arg Gln Ile Trp Leu Ala Glu Gln Ser Leu Lys Lys Arg 180 185 190 Trp Gly Ile Pro Asp Ser Met Ser Leu Arg Glu Ala Leu Leu Leu Ser 195 200 205 Ser Asn Lys Phe His Gly Asp Gly Asn Ala Leu Glu Lys Thr Asn Ala 210 215 220 Met Thr Leu Arg Glu Asn Gly Asn Thr Asn Arg Tyr Ser Val Val Val 225 230 235 240 Asn Ala Gly Thr Gln Val Leu Ser Leu His Lys Tyr Lys * 245 250 <210> 1482 <211> 124 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2291..2662) <400> 1482 Val Leu Lys Ile Leu Met Gln Gly Met Ser Phe Ser Glu Ile Ala Arg 1 5 10 15 Tyr Glu Gln Arg Ser Ser Lys Thr Leu His Ala Ile Ala Thr Arg Ala 20 25 30 Leu Met Lys Leu Gly Leu Gly Thr Leu Ser Asp Phe Arg Leu Leu Tyr 35 40 45 Thr Gly Cys Gly Asp Ser Arg Val Lys Arg Asn Ile Arg Leu His Ala 50 55 60 Arg Tyr Val Gly Gln His Ser Ala His Arg Leu Thr Gln Tyr Val Gln 65 70 75 80 Asn Met Val Ser Gly Ile Leu Tyr Pro Glu Lys Val Ala Val Gly Glu 85 90 95 Ser Ile Asn Ser Asp Ala Ile Ser Gly Lys Val Leu Pro Gly Gln Arg 100 105 110 Lys Asn Ile Ser Lys Lys Arg Pro Gly Leu Leu * 115 120 <210> 1483 <211> 56 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2918..3085) <400> 1483 Met Lys Lys Pro Leu Val Ile Ile Ser Ala Cys Gln Phe Thr Arg Leu 1 5 10 15 Ala Leu Glu Ser Leu Ile Pro Ala Asp Arg Tyr Ile Val Arg Val Tyr 20 25 30 Ser Asn Val Thr Thr Glu Val Glu Phe Val Leu Lys Thr Ser Cys Gly 35 40 45 Tyr Leu Leu Ala Asp Ile Pro * 50 55 <210> 1484 <211> 53 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3415..3573) <400> 1484 Met Leu Arg His Ala Cys Gly Phe Ala Leu Ala Asp Asn Gly Val Asp 1 5 10 15 Thr Arg Leu Leu Gln Asp Tyr Leu Gly His Arg Asn Ile Gln His Thr 20 25 30 Val Arg Tyr Thr Ala Ser Asn Ala Ala Arg Phe Lys Gly Val Trp Lys 35 40 45 Lys Lys Pro Arg * 50 <210> 1485 <211> 147 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3594..4034) <400> 1485 Leu Gln Ala Tyr Leu Ser Gly Cys Ala Ser Leu Phe Tyr Asn Cys Thr 1 5 10 15 Arg Trp Arg Met Thr Arg Lys Tyr Leu Thr Gln Asp Glu Val Tyr Arg 20 25 30 Leu Met Asp Ala Ala Gln Ser Met Ser Phe Pro Glu Arg Asn Arg Cys 35 40 45 Leu Ile Met Met Ala Phe Ile His Gly Phe Arg Ala Ser Glu Leu Leu 50 55 60 Asp Leu Arg Leu Ser Asp Ile Asp Ala Ser Gly Lys Gln Leu Asn Ile 65 70 75 80 Arg Arg Ile Lys Asn Gly Phe Ser Thr Thr His Pro Leu Leu Pro Asp 85 90 95 Glu Tyr Asn Leu Ile Lys Leu Trp Leu Lys Gln Arg Lys Leu Ile Glu 100 105 110 Asn Gly Val Glu Gly Asp Trp Leu Phe Leu Ser Arg Lys Arg Arg Pro 115 120 125 Ile Ser Arg Gln His Phe Phe Leu Ser Phe Val Arg Leu Glu Asp Val 130 135 140 Gln Asp * 145 <210> 1486 <211> 45 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4221..4355) <400> 1486 Met Cys Val Thr Ser Asn Val Leu Val Met Phe Ser Ser Phe Glu Ile 1 5 10 15 Phe Asp Val Ile Ser Tyr Lys Val Val Phe Ile Val Tyr Leu Ile Asp 20 25 30 Phe Ile Cys Ile Leu Ser Phe Asn Glu Val Ile Val * 35 40 <210> 1487 <211> 4905 <212> DNA <213> Escherichia coli O157:H7 <400> 1487 cactaaagag atagccaaac tggctggaca aaagcttgtt gctcgcgcga agtcggggca 60 atatgttcag ggagttaatg gtaaatggtt gcgcaaataa attatagttg gctacaaaat 120 gtatctatta atgtaatgat cttttacagt atttaaactg acgttagcat gcttaattac 180 cgtgggtatt tctacaaaaa ccttatatat ccttccctta aataacaaat cattaccaat 240 atatatataa tcacaaaata tatatgcagc gtcaatgaat tattagtgtg tttttgtttt 300 ttgtcgttaa tttttagatt gaagtgagtt ttttgtggaa tataattcca tcaactgttt 360 tttttgtatg cttttacttg cctgatttta atattgattt tgtgaattat ataagcattt 420 ctttactgct tatttcacta tgaatattta ctacgattta tcttcaaatt ctgcatggct 480 tgttacgcac ggtctagatc taaggaattt tatatgcaaa ggaaaaaatt attgtctgtt 540 tgtgttgcca tggcgttaag tagccagaca tgggctgcgg atacttcaat acccgactca 600 accgaaaaaa cacgtaagtc cagtaagata acatgtccgg caaatattca ttccctgagc 660 aaagagcagc tagaaaattt atccgcggag tgcagagaaa ataaagatag tgcagtttta 720 ccatgggcag ctgcaggtct tgctgcagta gctacgggaa ttgctatata taccttaagt 780 gacgatgaca atcaccacca taataactcc ccagttccgg atgatggcgg tgatacgcct 840 gttccgccag acgacggcgg tgatacgcca gttccggatg atggcggtga tacgcctgtt 900 ccgccagacg acggcggtga tacgccagtt ccgcctgatg acggcggtga tacgccggtt 960 ccgccagatg acggcggtga tacgccagtt ccgccagacg atggtggcga taccccggtt 1020 aaacacaatc ctgtcgtcta taaaaatggc gtaacttggg atcaggatgc aaaaactgtc 1080 aaaattcgcg aaactacctt tacctacagc caaaatgccg atgggagcta caccttaacg 1140 gcgcctgagg gcaaggagac gatagttaag tcctggacag tccatgacga cagcaacacc 1200 gttgtctttg atggcgtaaa tacctcaggt ggcatcacct ggagttacga cgatgatgga 1260 ctcatccaca tcactaaaga ggccggcgtc gttgttgacg gcacaaccgg gaatgcgatt 1320 gagtttggta acgcgatcat caccgatcag ggcggcaaca cggcgctgaa tggcggtact 1380 gtcatgacgg ttgatggtga caacatctcc ctcaacaacg acggcaaaac gacggccatc 1440 ggagaaggct cggttgtcgg tatactcact ggcgacaata tcaccattaa caataatggc 1500 gagacggaag ttgatggcgg taccgcggta atcatcaatg gcgataatac caagctaaac 1560 actgcgggcg actcgaccat caccaatggt ggtacgggta gccttatcaa tggcgataat 1620 gcgcgggtcg ataatcaagg taccatgagc gttgacggag agaattccac tggctcgaaa 1680 attgtcggtg acggtgccac catcaaacag gaaggcgact tatacgtaag cggtggtgcg 1740 cacggtattg acgttgacgg caatgatacg ttcgttagca acaaaggtaa tattacggtc 1800 atcgaagata actctattgg catgctgctt gatggtgatg gcgtcagcgt gatcaacatg 1860 ggcgacctca atgttggtca ggccgcagcg ggtgaaaatg ccattggcat tcagatcgac 1920 ggtgataatg cgacatttgt taacgttggt gatatttccg cgaccaatgc cggaaccggt 1980 gtcagcgttg ctggggataa agctaatatt tcactcgcgg gtgggttaga cgttggggat 2040 ttctccaccg gtcttgatgt ctctggcaat aataacaaca tgacgctggc gacttatgag 2100 ctgaatgtga cagggcaaaa agcgacgggt gttaatgttt cgggtgatgg taatactatc 2160 gaaatagcgg gcagtattct ggttgataaa gatcagaaag ccgataatgc gcagccttac 2220 ttctttaatc cctcaaccgg ggtaaatatc agcggtgaca acaacgacgt cacgctggat 2280 ggtcagttaa ccgttgttgc tgatagtaaa accacgtcgc gttcctatgc gagttacgac 2340 ggtgctcagg aacacattgc aggtattgtt attgctggcg atgacaatac ctttacgctt 2400 aatggcggtg tccattttgt cggtgaaaaa aatgtcatgg atgatggctc aaaaccatca 2460 gcttctcgac gtggtatcgg agacacaccg cttattaacg ttgatgggca ttccccggtc 2520 tacctgaatg gtgagtcaac catcagcggc gagttcccgc tggggttcga aaatctcatt 2580 cagttgagcc atggcgcgga gctggagatt ggcgctgacg caacgtttga tatgagtgat 2640 gtggattctt tcacttatta ttatcgtgta gcgttatcca ccattagtat tgattctggt 2700 gcgaaggcga caaacaacgg tgaagtggaa ctgaaaaata tcggttttgc ggctgcctgg 2760 aataaagatt caacggtaat caataacgga tccattggcc tggcgatgta cgattttggt 2820 accgacccgg caccaaaagt ctttgatgtt gaatacggtg ggattggcgt taacaatggt 2880 accatgacca ccaaaatgat gaatcagcac agtgtgctga attatccggc agagtggaac 2940 ttgtctgatg gtacctcttt caataacaag gcattagggc tgacaggtat gcttgccagc 3000 tactcgtcat ccattctgaa cggcgaaacg ggtattattg atatgtatgg ccgtggcagt 3060 gtagggatgc tagccatcga taaatcaacc gcggataacg aagggcaaat caccctggat 3120 acgctgtggg ttgatgaaaa tgatgaaaca tcgctgcgta ataatgttgc aaatagcacg 3180 gcgaaagatt tcggtgtggg aatggcttca ggtaccgatg cctataatgg ggcattaact 3240 aaagccacgg caaccaacca cgagaatggt gtgattactg tctacaacgc cggtgcgggg 3300 atggcggcgt atgggaatac taatacggtc attaaccagg gaaccatcaa cctggagaaa 3360 aatgaaaatt acaacgattc tctcggtgtg aataaactcg tcggcatggc ggtttatcac 3420 gaaggcaccg ccattaatga ccagacaggc gtaatcaaca ttaacgcgga aaatggtcag 3480 gcattctata acgatggcac tgggcttatt atcaactatg gcacaatttg tacctttggc 3540 gtttgctagg gggccgatga atataatcca acggataatt atattgctga tttatatgat 3600 gatggcgctg tattaagttc tgcgggtgag accgtattat tatcgtcagg tgcgattatc 3660 aacggggatg tcaccagtgc gggtgctgtt aaaaatggaa cgatcaggat actcgaaaat 3720 ggtgcgctgg ttaacgagtc gagcggaacc attagctcag ccatcgtcgt gaatgaaggc 3780 ggtgcgttaa ccaatgaagg tgtattgaac acggtgactc tggaaggagg aaccttcaat 3840 aacaacggaa cgcttaatga cgtcgtaaaa attgagaaaa acagcaacgc ggtaattaat 3900 aacaccggtt ccctgtcaac tttacaactt cacgatggta cggtgaataa cagcggtatt 3960 gcgtcggcgc gcgttaacgc tcagggcgat gcggtattca ataaccttgc aggcggcgag 4020 gcgcgtaaag gcgcgattct ctataactct gcggtagtga ataacgcggg tacctggaaa 4080 atgggttatc aggatgaaaa caacaatgcc gggacgctgg atattgacga taagtcaacg 4140 ttcaacaaca gcggcaaact catccttgat aacagcaaaa acgccattcg cttccagggc 4200 agcaatgcta acgccacgtt atataacacc ggtgaaatga cgctggatgc cgcattaggt 4260 gcgggcgcta ttctctacga cgatggcgcc agcgagttta ttaacaaggg cgtggtggat 4320 gcgaaagtca ccgtggcggt aagtactgcc ggtgcgacag aaagcgatgc cttcttgtgg 4380 aaccaggatg gcggggtaat taacttcgat aaagacaacg ccagcgcggt taaattcacc 4440 cacaacaact atgttgctct caacgatggt gtaatgaaca tcagcggcaa caacgccgtg 4500 gcgatggaag gcgataaaaa cgcacagctg gttaacaacg gcgttatcaa tctcggtacc 4560 gaaggcacca ccgataccgg attgactggt atgcaactgg atgccaatgc caccgccgat 4620 gcggtaattg agaacaacgg cacgatcaat atttttgcta acgactcgtt tgcgttcagc 4680 gtactgggca cagaaggtca tatcgttaac aacggtacgg tggtgattgc cgacggcgtg 4740 actggttcgg ggttgattaa gcagggcgac agcgtgaatg tggaaggggt gaacggcaac 4800 agcggtaaca ataccgaagt gcattacacc gactacacgt tgccggacat gccaaacact 4860 tacaccactt cacctttcag tgaaacgact gatagcggta gtagc 4905 <210> 1488 <211> 1012 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(514..3549) <400> 1488 Met Gln Arg Lys Lys Leu Leu Ser Val Cys Val Ala Met Ala Leu Ser 1 5 10 15 Ser Gln Thr Trp Ala Ala Asp Thr Ser Ile Pro Asp Ser Thr Glu Lys 20 25 30 Thr Arg Lys Ser Ser Lys Ile Thr Cys Pro Ala Asn Ile His Ser Leu 35 40 45 Ser Lys Glu Gln Leu Glu Asn Leu Ser Ala Glu Cys Arg Glu Asn Lys 50 55 60 Asp Ser Ala Val Leu Pro Trp Ala Ala Ala Gly Leu Ala Ala Val Ala 65 70 75 80 Thr Gly Ile Ala Ile Tyr Thr Leu Ser Asp Asp Asp Asn His His His 85 90 95 Asn Asn Ser Pro Val Pro Asp Asp Gly Gly Asp Thr Pro Val Pro Pro 100 105 110 Asp Asp Gly Gly Asp Thr Pro Val Pro Asp Asp Gly Gly Asp Thr Pro 115 120 125 Val Pro Pro Asp Asp Gly Gly Asp Thr Pro Val Pro Pro Asp Asp Gly 130 135 140 Gly Asp Thr Pro Val Pro Pro Asp Asp Gly Gly Asp Thr Pro Val Pro 145 150 155 160 Pro Asp Asp Gly Gly Asp Thr Pro Val Lys His Asn Pro Val Val Tyr 165 170 175 Lys Asn Gly Val Thr Trp Asp Gln Asp Ala Lys Thr Val Lys Ile Arg 180 185 190 Glu Thr Thr Phe Thr Tyr Ser Gln Asn Ala Asp Gly Ser Tyr Thr Leu 195 200 205 Thr Ala Pro Glu Gly Lys Glu Thr Ile Val Lys Ser Trp Thr Val His 210 215 220 Asp Asp Ser Asn Thr Val Val Phe Asp Gly Val Asn Thr Ser Gly Gly 225 230 235 240 Ile Thr Trp Ser Tyr Asp Asp Asp Gly Leu Ile His Ile Thr Lys Glu 245 250 255 Ala Gly Val Val Val Asp Gly Thr Thr Gly Asn Ala Ile Glu Phe Gly 260 265 270 Asn Ala Ile Ile Thr Asp Gln Gly Gly Asn Thr Ala Leu Asn Gly Gly 275 280 285 Thr Val Met Thr Val Asp Gly Asp Asn Ile Ser Leu Asn Asn Asp Gly 290 295 300 Lys Thr Thr Ala Ile Gly Glu Gly Ser Val Val Gly Ile Leu Thr Gly 305 310 315 320 Asp Asn Ile Thr Ile Asn Asn Asn Gly Glu Thr Glu Val Asp Gly Gly 325 330 335 Thr Ala Val Ile Ile Asn Gly Asp Asn Thr Lys Leu Asn Thr Ala Gly 340 345 350 Asp Ser Thr Ile Thr Asn Gly Gly Thr Gly Ser Leu Ile Asn Gly Asp 355 360 365 Asn Ala Arg Val Asp Asn Gln Gly Thr Met Ser Val Asp Gly Glu Asn 370 375 380 Ser Thr Gly Ser Lys Ile Val Gly Asp Gly Ala Thr Ile Lys Gln Glu 385 390 395 400 Gly Asp Leu Tyr Val Ser Gly Gly Ala His Gly Ile Asp Val Asp Gly 405 410 415 Asn Asp Thr Phe Val Ser Asn Lys Gly Asn Ile Thr Val Ile Glu Asp 420 425 430 Asn Ser Ile Gly Met Leu Leu Asp Gly Asp Gly Val Ser Val Ile Asn 435 440 445 Met Gly Asp Leu Asn Val Gly Gln Ala Ala Ala Gly Glu Asn Ala Ile 450 455 460 Gly Ile Gln Ile Asp Gly Asp Asn Ala Thr Phe Val Asn Val Gly Asp 465 470 475 480 Ile Ser Ala Thr Asn Ala Gly Thr Gly Val Ser Val Ala Gly Asp Lys 485 490 495 Ala Asn Ile Ser Leu Ala Gly Gly Leu Asp Val Gly Asp Phe Ser Thr 500 505 510 Gly Leu Asp Val Ser Gly Asn Asn Asn Asn Met Thr Leu Ala Thr Tyr 515 520 525 Glu Leu Asn Val Thr Gly Gln Lys Ala Thr Gly Val Asn Val Ser Gly 530 535 540 Asp Gly Asn Thr Ile Glu Ile Ala Gly Ser Ile Leu Val Asp Lys Asp 545 550 555 560 Gln Lys Ala Asp Asn Ala Gln Pro Tyr Phe Phe Asn Pro Ser Thr Gly 565 570 575 Val Asn Ile Ser Gly Asp Asn Asn Asp Val Thr Leu Asp Gly Gln Leu 580 585 590 Thr Val Val Ala Asp Ser Lys Thr Thr Ser Arg Ser Tyr Ala Ser Tyr 595 600 605 Asp Gly Ala Gln Glu His Ile Ala Gly Ile Val Ile Ala Gly Asp Asp 610 615 620 Asn Thr Phe Thr Leu Asn Gly Gly Val His Phe Val Gly Glu Lys Asn 625 630 635 640 Val Met Asp Asp Gly Ser Lys Pro Ser Ala Ser Arg Arg Gly Ile Gly 645 650 655 Asp Thr Pro Leu Ile Asn Val Asp Gly His Ser Pro Val Tyr Leu Asn 660 665 670 Gly Glu Ser Thr Ile Ser Gly Glu Phe Pro Leu Gly Phe Glu Asn Leu 675 680 685 Ile Gln Leu Ser His Gly Ala Glu Leu Glu Ile Gly Ala Asp Ala Thr 690 695 700 Phe Asp Met Ser Asp Val Asp Ser Phe Thr Tyr Tyr Tyr Arg Val Ala 705 710 715 720 Leu Ser Thr Ile Ser Ile Asp Ser Gly Ala Lys Ala Thr Asn Asn Gly 725 730 735 Glu Val Glu Leu Lys Asn Ile Gly Phe Ala Ala Ala Trp Asn Lys Asp 740 745 750 Ser Thr Val Ile Asn Asn Gly Ser Ile Gly Leu Ala Met Tyr Asp Phe 755 760 765 Gly Thr Asp Pro Ala Pro Lys Val Phe Asp Val Glu Tyr Gly Gly Ile 770 775 780 Gly Val Asn Asn Gly Thr Met Thr Thr Lys Met Met Asn Gln His Ser 785 790 795 800 Val Leu Asn Tyr Pro Ala Glu Trp Asn Leu Ser Asp Gly Thr Ser Phe 805 810 815 Asn Asn Lys Ala Leu Gly Leu Thr Gly Met Leu Ala Ser Tyr Ser Ser 820 825 830 Ser Ile Leu Asn Gly Glu Thr Gly Ile Ile Asp Met Tyr Gly Arg Gly 835 840 845 Ser Val Gly Met Leu Ala Ile Asp Lys Ser Thr Ala Asp Asn Glu Gly 850 855 860 Gln Ile Thr Leu Asp Thr Leu Trp Val Asp Glu Asn Asp Glu Thr Ser 865 870 875 880 Leu Arg Asn Asn Val Ala Asn Ser Thr Ala Lys Asp Phe Gly Val Gly 885 890 895 Met Ala Ser Gly Thr Asp Ala Tyr Asn Gly Ala Leu Thr Lys Ala Thr 900 905 910 Ala Thr Asn His Glu Asn Gly Val Ile Thr Val Tyr Asn Ala Gly Ala 915 920 925 Gly Met Ala Ala Tyr Gly Asn Thr Asn Thr Val Ile Asn Gln Gly Thr 930 935 940 Ile Asn Leu Glu Lys Asn Glu Asn Tyr Asn Asp Ser Leu Gly Val Asn 945 950 955 960 Lys Leu Val Gly Met Ala Val Tyr His Glu Gly Thr Ala Ile Asn Asp 965 970 975 Gln Thr Gly Val Ile Asn Ile Asn Ala Glu Asn Gly Gln Ala Phe Tyr 980 985 990 Asn Asp Gly Thr Gly Leu Ile Ile Asn Tyr Gly Thr Ile Cys Thr Phe 995 1000 1005 Gly Val Cys * 1010 <210> 1489 <211> 4866 <212> DNA <213> Escherichia coli O157:H7 <400> 1489 ctcgactttt atggtgttct catcccataa cgatgacgtt ggcaataaag acaattttgc 60 gcattttgct gaaaagtaag aaaggatttt tgacaggttt tacagacttt gcgattagca 120 tgaagattca caatttttgc cggtagaatc gtcaattcaa cggtcattgc ctgatgaaaa 180 caaacagcaa tacaattttg gcatccgtta cacaaggcat catttatttg taaatggcct 240 tcgttaagcg aaaagacctg ttgctcgcag gcccgccagc atgcaccgca aagctgacac 300 ttttgaggat ccatcatcgg gcgagcatca ctaatctggg gccataaata atgtaaccga 360 cgtaatcctg gttgtatttg tgtcatctga acatccgcac gctgcacatg gaacaaacga 420 cgccgggaaa cattcacctc actggtatgt ggagatacca cagaccagcc ttcctcgcca 480 tattgccgta agcattcgtt taacagcaat aatgcgcgct cccatgcctt cgcctgactc 540 agatcaatcg cgatcgctgt gatcccctgc tctttatgcc atagcaaaag ttcttccagc 600 gtcggcgcaa tagtggtgaa aggtgcgacc agggtgtgat tgcaaaaata acgtaaaggg 660 gaattaacgc cacgaatagc ctcttgcgga caaataaact ggcaaaccgc acaatcaata 720 cattgttccg cgtcgaccgc tatgccctct tctgtcagcg ttagcgcctg tgccgggcaa 780 gcctcgacac aggcatgaca tgttgcaaaa cgaaagcgtt ggcgcgcgca ttccgcgcca 840 atcgttatgt tatgacttaa cattagccga tactaaaaaa gacaaaacgc agcataactt 900 cactccccac tagcattacg ctaccgaata acgccgccgg gatattcttt ttacaaccac 960 cgacagcaaa gaacatcatc ccaatgacgg aaattcccca gcttagtgtc agtatgggtt 1020 ttaactgtcc cagcatcgct aatggcgcat gtggcaatgt ggctatctgc atcgcatttg 1080 ccgttaaatc ccctatccac aacggctgaa ccaacaaacg cagcagaacc aggagagcga 1140 tcaccaacac gcatccatta cgcagggcat caatctgcgg caaaattccg ctaatacgaa 1200 acactgctac cagcgctgaa ccgagaattc ccactgtacc taagaacata atcagcgtgt 1260 tgtaatgctg ccaggtgata atcgacgtat ggatgtaaac ttgcgccatg cagaaaacat 1320 caacaatccc gaccactgcc gctagcataa gcaggagttg ccagccgcct ttgcgtaaca 1380 tgaccagtaa tgtggataaa cccaatagcg ccagatacag cgcaccaaag ataatttccc 1440 gactcagcca tgaactggaa aagtggctca gcgcatgcat cgcattaagt ggataaccca 1500 ggtgtaaggt agaaatcagt aaccctacgg cacctgccaa aaaagccaac agtaatggcg 1560 gccgcataac cgggcgggcg ctggaggtga ttaaaatatg acgatgaaga aacgccagcc 1620 acaacgtcat accgaccgat gcctgtaaca acagcgtaaa agccattaac ggtaattcat 1680 gcatgatgtg acgcctcctt ttccgcgccc tgatgcggtt taatcaccag atttggctgc 1740 gtaatcgacg aatcaggtaa acctttcaca tcactgacat cgccatactt ttcacgcaac 1800 tcatcaatag ggccgaactt aatcgccccc aacgggcacg ttgccacgca aatgggttgt 1860 tctcctttag cttgcagatc aatacagaaa tcgcatttcg acatctgccc ggtctgctca 1920 ttcatttgtg gtgcgccgta aggacaggac caggcgcagt aaccgcaacc gacgcactta 1980 tcagtattca cgcgcacaat accgtctccg ggacgcttat gcatcgccat cgtcgggcaa 2040 tttttggtac agatcggatc cgcgcaatgg ttacaggaaa cagaaagggt ataagcaaag 2100 acattatgac tcacaccgcc ctctccagtg gcgatgaagc cacctccgtt cacttcatac 2160 acgcggcgaa aacgtcgccc aacctcaagg ttgtttttgt ctttacaggc cacctgacac 2220 gctttacagc ccgaacaacg cgaagagtca ataaagaacc ctaattgttt gtcgctgaca 2280 gatgcaaatt ctttaaattg gctcatgctt tctcaacctc caccagcatt gtttgatgcg 2340 aattcccttt cgccagcgcc gtaatgcggg tcgaactcag tacattggca cagcctccgc 2400 gatcgatacc ttgtgcatcc ggttgccacc atgcccccgc ctgcatagca actacgccag 2460 ggatgatacg gggggttatt tccaccggga taatgctcac accacgatcg ttataaattt 2520 ttacgctatc tccttcgcta atcccgcgct gttttgcatc ttgcggattc agccagagtt 2580 tttgcgtctg aacttcttgc agccacgggt tagcatactg ggtggaatta gcacggtttt 2640 tccctttcca ggtgatgagc tgcaacgggt atttcgccgt cagtttatct tctggccctt 2700 caaaggcagg gacatagtgc gaaagcgcgg gaatttctgg atcttgcata tcaaaaagac 2760 gcttagagaa gatctcaatt ttgccggaag gcgtcgggaa aggattattc tgcggatcgc 2820 gaatatttgc ttcgaaagcg atgtgcggcg cgcttttgaa aagatgtcga cgtgtttttt 2880 gcagggttgc gaagtccggc aaattttcat ccggcatcgc cagacgagtt tgctcccaga 2940 tatgctcgat ccattgcttc tcatcacgtc cttgactgaa ctcggcttcg acacccagtt 3000 ttttcgccac gtcacgcaac cagtcataat cggtgcgacg ttcaaaatcc ggctcaatcg 3060 gtttttctga cagaataaga tagctcgcag ttccccatgt ttcgccgata ttccagcgtt 3120 ccataaagct ggtttccggc agcaacacat cggcatattt cgcgctcgga gtcatgaaca 3180 gatcgctgag tacgatgaat tctattttag attcgtcttc aaggagcttc gcggcctggt 3240 ggacgtccgg gttctggttc gccagataat tacctgccag tgagaacagc aggcggatat 3300 tactgtcgag tttatcgaca cctttaagcc catcttgcgg cgtaacttta gaagcatcat 3360 ccgccgcctg catccagttc ataatcgaga ttttcgcttg taccggattt tctggcatat 3420 ctggtccaac gcagaattta cgattagaac taccgccgta acctgccgcc cagccacctt 3480 tgatgccgac gttaccggta atcgaggcca gtaaagttga acctcgggcg gtgcgttcgc 3540 cgcaaatatg tcgctgtggc ccccatccct gaatcaacgc tgcgggtttt gtagtggcgt 3600 aatcgcgtgc cagttgacga atggattgtg ctggaacgtg ggtaattttt tctgcccatt 3660 ccggcgtttt gtgtatccca tcttttgcgc caaaaaggta ggcaaccaac gattcgttgg 3720 ctggtacgcc ttccggcatg gagttttcat caaaaccgag agtatatgtg tcgataaatg 3780 tcttatcgtg gagattctcg ctgataatga cgtacatcat cgcgtccatc aacgcattgt 3840 ccgtggtcgg caacagcggg atccactgat cggcaagtga agatacggtg tcggaatagc 3900 gcggatccac cacgataaaa cgtgtaccgt tttgcttcat tttttgaaaa tagtaattgg 3960 tgtgaccgaa tatggtttcc gttgggttat gcccccagag aatcaccagt ttggtatcca 4020 gaagagtatc catcgagtta ccgctcgcgg ccacgccata cgtgtaaggc gtggccgccg 4080 cagtattacc cagactaact gagtgataat attcaagata accaccggtt aaatttaaca 4140 gccgacgcgc catcgcatcg ccagaaaatg ttccaccaga aacagccgtc ccgacatgga 4200 cataacgtga agctgggcca tattgttgcg tgatcctttt caggttatcg gcaattaagg 4260 tcgtcgcctc atcccatgag atacgctcaa atttaccctc gcctcgttta cctacccgct 4320 tcatcggata tttcaaacgg tctggatgat aaacaaattt acgatagccg cgaccacgaa 4380 cacaggcgcg cataatcggc atttgtggat ccaattcgtt atcgggaagc gtggtaattt 4440 gcgtcaccac gccgtcgcgc atatgcgccc gaatatcgca cttaccaccg cagtcaaatg 4500 tgctacaggt gggcacgact ttatcagcta ctggagctgt aacttctggc gacgcatctg 4560 gggattgcgc ctttgcggta gaagaaataa aaggcaaagt gataagcgcg gaagtcgctt 4620 gtaaaaaact acgtcgtgat acttgcggaa atgtaatgcg ttccttttcg tctggcgtat 4680 ccatcttgcg ttcccgaaaa tgaaaaaata aatattcacg tatttattcg agaacaatgc 4740 tgataacaat caaataatta gtcgtttaaa aaaacgtgag attattaaat tattaatgca 4800 ttccaaatat aaataccata attagattaa taaatatttt gtatatttca ctgaaatgaa 4860 aaatgt 4866 <210> 1490 <211> 285 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(9..863) <400> 1490 Met Leu Ser His Asn Ile Thr Ile Gly Ala Glu Cys Ala Arg Gln Arg 1 5 10 15 Phe Arg Phe Ala Thr Cys His Ala Cys Val Glu Ala Cys Pro Ala Gln 20 25 30 Ala Leu Thr Leu Thr Glu Glu Gly Ile Ala Val Asp Ala Glu Gln Cys 35 40 45 Ile Asp Cys Ala Val Cys Gln Phe Ile Cys Pro Gln Glu Ala Ile Arg 50 55 60 Gly Val Asn Ser Pro Leu Arg Tyr Phe Cys Asn His Thr Leu Val Ala 65 70 75 80 Pro Phe Thr Thr Ile Ala Pro Thr Leu Glu Glu Leu Leu Leu Trp His 85 90 95 Lys Glu Gln Gly Ile Thr Ala Ile Ala Ile Asp Leu Ser Gln Ala Lys 100 105 110 Ala Trp Glu Arg Ala Leu Leu Leu Leu Asn Glu Cys Leu Arg Gln Tyr 115 120 125 Gly Glu Glu Gly Trp Ser Val Val Ser Pro His Thr Ser Glu Val Asn 130 135 140 Val Ser Arg Arg Arg Leu Phe His Val Gln Arg Ala Asp Val Gln Met 145 150 155 160 Thr Gln Ile Gln Pro Gly Leu Arg Arg Leu His Tyr Leu Trp Pro Gln 165 170 175 Ile Ser Asp Ala Arg Pro Met Met Asp Pro Gln Lys Cys Gln Leu Cys 180 185 190 Gly Ala Cys Trp Arg Ala Cys Glu Gln Gln Val Phe Ser Leu Asn Glu 195 200 205 Gly His Leu Gln Ile Asn Asp Ala Leu Cys Asn Gly Cys Gln Asn Cys 210 215 220 Ile Ala Val Cys Phe His Gln Ala Met Thr Val Glu Leu Thr Ile Leu 225 230 235 240 Pro Ala Lys Ile Val Asn Leu His Ala Asn Arg Lys Val Cys Lys Thr 245 250 255 Cys Gln Lys Ser Phe Leu Thr Phe Gln Gln Asn Ala Gln Asn Cys Leu 260 265 270 Tyr Cys Gln Arg His Arg Tyr Gly Met Arg Thr Pro * 275 280 <210> 1491 <211> 274 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(863..1684) <400> 1491 Met His Glu Leu Pro Leu Met Ala Phe Thr Leu Leu Leu Gln Ala Ser 1 5 10 15 Val Gly Met Thr Leu Trp Leu Ala Phe Leu His Arg His Ile Leu Ile 20 25 30 Thr Ser Ser Ala Arg Pro Val Met Arg Pro Pro Leu Leu Leu Ala Phe 35 40 45 Leu Ala Gly Ala Val Gly Leu Leu Ile Ser Thr Leu His Leu Gly Tyr 50 55 60 Pro Leu Asn Ala Met His Ala Leu Ser His Phe Ser Ser Ser Trp Leu 65 70 75 80 Ser Arg Glu Ile Ile Phe Gly Ala Leu Tyr Leu Ala Leu Leu Gly Leu 85 90 95 Ser Thr Leu Leu Val Met Leu Arg Lys Gly Gly Trp Gln Leu Leu Leu 100 105 110 Met Leu Ala Ala Val Val Gly Ile Val Asp Val Phe Cys Met Ala Gln 115 120 125 Val Tyr Ile His Thr Ser Ile Ile Thr Trp Gln His Tyr Asn Thr Leu 130 135 140 Ile Met Phe Leu Gly Thr Val Gly Ile Leu Gly Ser Ala Leu Val Ala 145 150 155 160 Val Phe Arg Ile Ser Gly Ile Leu Pro Gln Ile Asp Ala Leu Arg Asn 165 170 175 Gly Cys Val Leu Val Ile Ala Leu Leu Val Leu Leu Arg Leu Leu Val 180 185 190 Gln Pro Leu Trp Ile Gly Asp Leu Thr Ala Asn Ala Met Gln Ile Ala 195 200 205 Thr Leu Pro His Ala Pro Leu Ala Met Leu Gly Gln Leu Lys Pro Ile 210 215 220 Leu Thr Leu Ser Trp Gly Ile Ser Val Ile Gly Met Met Phe Phe Ala 225 230 235 240 Val Gly Gly Cys Lys Lys Asn Ile Pro Ala Ala Leu Phe Gly Ser Val 245 250 255 Met Leu Val Gly Ser Glu Val Met Leu Arg Phe Val Phe Phe Ser Ile 260 265 270 Gly * <210> 1492 <211> 210 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1677..2306) <400> 1492 Met Ser Gln Phe Lys Glu Phe Ala Ser Val Ser Asp Lys Gln Leu Gly 1 5 10 15 Phe Phe Ile Asp Ser Ser Arg Cys Ser Gly Cys Lys Ala Cys Gln Val 20 25 30 Ala Cys Lys Asp Lys Asn Asn Leu Glu Val Gly Arg Arg Phe Arg Arg 35 40 45 Val Tyr Glu Val Asn Gly Gly Gly Phe Ile Ala Thr Gly Glu Gly Gly 50 55 60 Val Ser His Asn Val Phe Ala Tyr Thr Leu Ser Val Ser Cys Asn His 65 70 75 80 Cys Ala Asp Pro Ile Cys Thr Lys Asn Cys Pro Thr Met Ala Met His 85 90 95 Lys Arg Pro Gly Asp Gly Ile Val Arg Val Asn Thr Asp Lys Cys Val 100 105 110 Gly Cys Gly Tyr Cys Ala Trp Ser Cys Pro Tyr Gly Ala Pro Gln Met 115 120 125 Asn Glu Gln Thr Gly Gln Met Ser Lys Cys Asp Phe Cys Ile Asp Leu 130 135 140 Gln Ala Lys Gly Glu Gln Pro Ile Cys Val Ala Thr Cys Pro Leu Gly 145 150 155 160 Ala Ile Lys Phe Gly Pro Ile Asp Glu Leu Arg Glu Lys Tyr Gly Asp 165 170 175 Val Ser Asp Val Lys Gly Leu Pro Asp Ser Ser Ile Thr Gln Pro Asn 180 185 190 Leu Val Ile Lys Pro His Gln Gly Ala Glu Lys Glu Ala Ser His His 195 200 205 Ala * <210> 1493 <211> 794 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2303..4684) <400> 1493 Met Asp Thr Pro Asp Glu Lys Glu Arg Ile Thr Phe Pro Gln Val Ser 1 5 10 15 Arg Arg Ser Phe Leu Gln Ala Thr Ser Ala Leu Ile Thr Leu Pro Phe 20 25 30 Ile Ser Ser Thr Ala Lys Ala Gln Ser Pro Asp Ala Ser Pro Glu Val 35 40 45 Thr Ala Pro Val Ala Asp Lys Val Val Pro Thr Cys Ser Thr Phe Asp 50 55 60 Cys Gly Gly Lys Cys Asp Ile Arg Ala His Met Arg Asp Gly Val Val 65 70 75 80 Thr Gln Ile Thr Thr Leu Pro Asp Asn Glu Leu Asp Pro Gln Met Pro 85 90 95 Ile Met Arg Ala Cys Val Arg Gly Arg Gly Tyr Arg Lys Phe Val Tyr 100 105 110 His Pro Asp Arg Leu Lys Tyr Pro Met Lys Arg Val Gly Lys Arg Gly 115 120 125 Glu Gly Lys Phe Glu Arg Ile Ser Trp Asp Glu Ala Thr Thr Leu Ile 130 135 140 Ala Asp Asn Leu Lys Arg Ile Thr Gln Gln Tyr Gly Pro Ala Ser Arg 145 150 155 160 Tyr Val His Val Gly Thr Ala Val Ser Gly Gly Thr Phe Ser Gly Asp 165 170 175 Ala Met Ala Arg Arg Leu Leu Asn Leu Thr Gly Gly Tyr Leu Glu Tyr 180 185 190 Tyr His Ser Val Ser Leu Gly Asn Thr Ala Ala Ala Thr Pro Tyr Thr 195 200 205 Tyr Gly Val Ala Ala Ser Gly Asn Ser Met Asp Thr Leu Leu Asp Thr 210 215 220 Lys Leu Val Ile Leu Trp Gly His Asn Pro Thr Glu Thr Ile Phe Gly 225 230 235 240 His Thr Asn Tyr Tyr Phe Gln Lys Met Lys Gln Asn Gly Thr Arg Phe 245 250 255 Ile Val Val Asp Pro Arg Tyr Ser Asp Thr Val Ser Ser Leu Ala Asp 260 265 270 Gln Trp Ile Pro Leu Leu Pro Thr Thr Asp Asn Ala Leu Met Asp Ala 275 280 285 Met Met Tyr Val Ile Ile Ser Glu Asn Leu His Asp Lys Thr Phe Ile 290 295 300 Asp Thr Tyr Thr Leu Gly Phe Asp Glu Asn Ser Met Pro Glu Gly Val 305 310 315 320 Pro Ala Asn Glu Ser Leu Val Ala Tyr Leu Phe Gly Ala Lys Asp Gly 325 330 335 Ile His Lys Thr Pro Glu Trp Ala Glu Lys Ile Thr His Val Pro Ala 340 345 350 Gln Ser Ile Arg Gln Leu Ala Arg Asp Tyr Ala Thr Thr Lys Pro Ala 355 360 365 Ala Leu Ile Gln Gly Trp Gly Pro Gln Arg His Ile Cys Gly Glu Arg 370 375 380 Thr Ala Arg Gly Ser Thr Leu Leu Ala Ser Ile Thr Gly Asn Val Gly 385 390 395 400 Ile Lys Gly Gly Trp Ala Ala Gly Tyr Gly Gly Ser Ser Asn Arg Lys 405 410 415 Phe Cys Val Gly Pro Asp Met Pro Glu Asn Pro Val Gln Ala Lys Ile 420 425 430 Ser Ile Met Asn Trp Met Gln Ala Ala Asp Asp Ala Ser Lys Val Thr 435 440 445 Pro Gln Asp Gly Leu Lys Gly Val Asp Lys Leu Asp Ser Asn Ile Arg 450 455 460 Leu Leu Phe Ser Leu Ala Gly Asn Tyr Leu Ala Asn Gln Asn Pro Asp 465 470 475 480 Val His Gln Ala Ala Lys Leu Leu Glu Asp Glu Ser Lys Ile Glu Phe 485 490 495 Ile Val Leu Ser Asp Leu Phe Met Thr Pro Ser Ala Lys Tyr Ala Asp 500 505 510 Val Leu Leu Pro Glu Thr Ser Phe Met Glu Arg Trp Asn Ile Gly Glu 515 520 525 Thr Trp Gly Thr Ala Ser Tyr Leu Ile Leu Ser Glu Lys Pro Ile Glu 530 535 540 Pro Asp Phe Glu Arg Arg Thr Asp Tyr Asp Trp Leu Arg Asp Val Ala 545 550 555 560 Lys Lys Leu Gly Val Glu Ala Glu Phe Ser Gln Gly Arg Asp Glu Lys 565 570 575 Gln Trp Ile Glu His Ile Trp Glu Gln Thr Arg Leu Ala Met Pro Asp 580 585 590 Glu Asn Leu Pro Asp Phe Ala Thr Leu Gln Lys Thr Arg Arg His Leu 595 600 605 Phe Lys Ser Ala Pro His Ile Ala Phe Glu Ala Asn Ile Arg Asp Pro 610 615 620 Gln Asn Asn Pro Phe Pro Thr Pro Ser Gly Lys Ile Glu Ile Phe Ser 625 630 635 640 Lys Arg Leu Phe Asp Met Gln Asp Pro Glu Ile Pro Ala Leu Ser His 645 650 655 Tyr Val Pro Ala Phe Glu Gly Pro Glu Asp Lys Leu Thr Ala Lys Tyr 660 665 670 Pro Leu Gln Leu Ile Thr Trp Lys Gly Lys Asn Arg Ala Asn Ser Thr 675 680 685 Gln Tyr Ala Asn Pro Trp Leu Gln Glu Val Gln Thr Gln Lys Leu Trp 690 695 700 Leu Asn Pro Gln Asp Ala Lys Gln Arg Gly Ile Ser Glu Gly Asp Ser 705 710 715 720 Val Lys Ile Tyr Asn Asp Arg Gly Val Ser Ile Ile Pro Val Glu Ile 725 730 735 Thr Pro Arg Ile Ile Pro Gly Val Val Ala Met Gln Ala Gly Ala Trp 740 745 750 Trp Gln Pro Asp Ala Gln Gly Ile Asp Arg Gly Gly Cys Ala Asn Val 755 760 765 Leu Ser Ser Thr Arg Ile Thr Ala Leu Ala Lys Gly Asn Ser His Gln 770 775 780 Thr Met Leu Val Glu Val Glu Lys Ala * 785 790 <210> 1494 <211> 4716 <212> DNA <213> Escherichia coli O157:H7 <400> 1494 gattaagggt tgtttgaatt tcatggcctc tacctgattc agctaaagtc acccattctg 60 gatttatcac cagcccttta ccgatcgcaa caagtggcag gccagtggaa attgcttctt 120 gagcctgaga cggtgtgcgt attttacctg cagcgattac cggcactctg cctgcaatat 180 gatttaaaat caattcaata gttcgggggc catttggcga ctcaacaggg tagctatcgt 240 taatactgac cagcgaggta tgtatatacg aaataccgga tgaaatgagc cgatcaagga 300 gtttataagt atcctctatc cgcagccccc ctgttgcaga ttcttcagga gatattctgt 360 aaccgatggc aaagggcttt gtcgcatatt catagactac attttttact tcctgtaata 420 cggccagcgg gaagcgcata cgtccttcga gatctcctcc ccatcggtca ttacgctggt 480 taaatagagg ggagaaaaaa ttctgtagaa ggaatccgtg cgcaccatga agttcaatgc 540 catcaaaacc tgctttaatc gccctttttg tgacatctcc gaatgctcta atggtttcct 600 gaatttcgtt ttcagtcatt tccctgcttt gtaccactct cttcataaag tcaccagatt 660 ttacgcttga tgcgctggca ctaataacat cgttatttgg tacaagctcc gggatggctt 720 tattaccggc gtggaaaatc tgcaaaatag ccggagcacc gccacttttg gctgccgctg 780 ctaacttttc aaggctgtta atgaaacggt cgtcatacgc ggcaaattca tgagtaaacc 840 caatgccgct tggcgtgaca taggtacatc ctgttattac taaaccaaca ttttgtgagc 900 gacgtttata aaattcgagt tcttgctcag agatggttcc atcaggattc gctgaccagg 960 tcgtcatagg agccataacg atacgattac gtagctttat tttttctgtc agcataaaag 1020 gagaaaacaa tgatgggtgt ttatttgtca taacaatacc tcaaatgttt atctgatttt 1080 gatgcgtatg ttttaactgg ttagttgttg ccagctttgg aaccaagagt tctggcttta 1140 tttataatcc ctttaaaggg tttctaataa ttgagttgct gcttttttgt tttttaatga 1200 aatttctttt tgaataattt tattattgtt gtgtagtcaa taaaggataa atgtcaggga 1260 gataagggat ctccctgtaa aattattaca aatgtgtttt ataaaaagga attaatttat 1320 cgagtgcctg tttcacaggt tctggcttat catacaggtc gtaatgtgaa taaccttcaa 1380 ccacgaccag ctctttatgt tttgaagcag cgcggccaat aatttcgcag ccgtcacggt 1440 aggcaccaaa tgcgcccact ctatcgccca ccacaaccat tattggttga gttaacagca 1500 cttctgcaag atgaaatgca tcccaaccca cggcaacagt ctgatgtgag aatagcgaac 1560 gatttacccc attaggtgca tagcctcgtg gcgaacgata atattctgtg gcttcaaaaa 1620 ggtctatttc tgttagtccc gcttcaagag ctgcatccgg agaagagggg agtaaatcat 1680 ctacgcgaag ttttgcgccg ttagcttcgt ctgttctttg ttgcgccatt gcttcaagtg 1740 ctccgatagg attaaacgct gtaaatccct cacgcataag acgcccgtag tttgcacccg 1800 tgacagtacc aatagcttta attcggcgtt ctgtcattgc ggcattaatg gcatatccac 1860 ctccaccaca aatacccagt acaccaatac gcccggcatc aacgtaaggt aagctggtaa 1920 ggtaatcaac gacaatgctg aagtctttta ctcgcattgt tggatcttcc agataacgcg 1980 gttccccacc gctgcttccc tgaaaactag catcaaaagc aatgacgata aagccagctt 2040 ttgccagggc ggcaccatac acactacccg atgtctgttc tttgcagctt ccaattggat 2100 gggcgctgat aatggcagga tacttttttt cactattaaa atcgtcaggg aaatagatat 2160 cagcagctat atcccagtaa gtgtgtttta tcgaaacagt tttcatttca agctccgggg 2220 atttgcctaa acagatttaa atatcatttc tattatccgc aactggcatt tgtgttcata 2280 tcgagaacgg cgtaatagta tgacttgtat tggttatcat caatggtcta atatctatca 2340 cagtgttaag ttaaggttta caatgatgaa aatagagcct tcaattttgc cttctcttgc 2400 ctggtttgcg ctgattgttc gtgccggcag tttttccaga gccgtttctg aaatgggtat 2460 tacgctggcc gcattgtccc agaatttaaa atctcttgag gaacgtctta acaccaagct 2520 gatataccgt acgacccgca atatctcgct tactgaggaa ggacagcgtc tgtatgaagt 2580 gctggtgtcg gctttggggc aaattgatga tgctttgaaa gatgttggtg atacccaact 2640 tgaacctaca ggcctgttga gaataaattc ctcccgtgtt gcagcacgga tgcttgttga 2700 gcctcatatt ggcgagtttc ttactcgtta ccccaaaaca aagatagaac tcattatgga 2760 tgacggttta tctaacatta ttgcggacgg ctgtgatgtg ggcatacgtc ttgagcaagg 2820 actggatgag catatgactg ccgttcctgt ttctccgctt attaaactgg ttactgtggc 2880 atcgccagat tatttaaaag aacacggtat tcctgaaacg cctcaggaac tgagtaacca 2940 taattgcctt cggttgcggc ataaaagtag cggtgcactc tctgcatggg agttttctaa 3000 ggttgtgggg ggtaatgaag agttcgaaat agaggtttca ggtaagtata tttctaatga 3060 tgacgaaagc atgatacgaa tggcgctgaa tggaacgggt atcattcaac atctggattt 3120 tgcaatcgct gaacatatca atgcgggcaa gttacagccg attcttgagg attgggctgt 3180 ttcatttcct gggttttata tttatgtttc atcacgggtg agaatgccct ctaaagttcg 3240 tgcttttatt gattttatgg tggagaaaag agtaaaactc gaaaattgat gatatgtgta 3300 attgatggtt gctctgggcg aatatcggta agaggaataa cgtaatcatt aggatgcgtt 3360 tacataataa agtttctgat aattaatact tattttctat acggccataa tatcaattat 3420 cattatcacc agtaatgtgg ttaaaataat agtatctatg accgctacgg ttaacggtgg 3480 ttattttggg aggcgttaac acgtagcggc ttgtagttgt aagtcttgaa caggtacaaa 3540 gcctgaaatc aggaggatat cgctatcaaa cttcctttat ttcttctcgc agtttcgcat 3600 cttatagaag aatcctgtat ttccatcttc cacgatgaag cgatcgttaa aagttggacg 3660 acgaataaat gtcactccac ctattgttgc tttttgtttt ataccatcat caacattttc 3720 cagatctgga gagtacaatt gatctccatt tggcatttga acgatgaaat tgtttccatt 3780 atcgagaact gttgcggatt ttgacagaat ttgagtagcg gtatccaggc tggaaatcct 3840 aatgtcacaa acatatttgc ctggccccag atcttcttct gcaaatacag gtaaggaaaa 3900 taatgcaaat gcgaggatga gattcttatt catgcaaact ccaggaagat caataaaagc 3960 aatatgttac ataaaaagca cgtaaatgaa aagagcgatt ggttaatgag taatgctatt 4020 aatccccgca tggcctactt ttcattggct gcggtgttga acctcattga atatgggcaa 4080 gactctgact gagtgaccga cgtaaatagg tagatgcata atcgcttacc gccctgtaac 4140 tgcaaacggt gcccaggctt ctggctgaat accacggctt tgcatccacg gaacggcgtg 4200 tagctgctga ttgaaagggt taacttcaac ctggtttacc gctggaacga cgttattaaa 4260 ggcgataagg tcagccagtc ggtcaggatg gaagttactg acgccaatag cgcgaatttt 4320 accggcctgt tgcagctctt ccatggcacg ccaggcaccg tggacatcac cgtaaggctg 4380 atgaatcaaa tacaggtcaa cgtaatcaag ttgcagtcga ttcagagagc gttcgaactg 4440 ggctttggcc ccttcgtaac tggtatcctg caaccagagt ttcgtggtga caaagagttc 4500 gttacgggcg ataccgcttt gtttcagtgc gttcccgacc tggggttcat tttgatagga 4560 ggcggcggtg tcaatcagtc gataaccggt gttaatagcg tcaatgaccg ctctttcgca 4620 ttcggcggca tcggtcatct gaaatacacc aaagcccagc aggggcattt caataccgtt 4680 attcagtttt actttttgca tggtgttatc cttccg 4716 <210> 1495 <211> 307 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1286..2206) <400> 1495 Met Lys Thr Val Ser Ile Lys His Thr Tyr Trp Asp Ile Ala Ala Asp 1 5 10 15 Ile Tyr Phe Pro Asp Asp Phe Asn Ser Glu Lys Lys Tyr Pro Ala Ile 20 25 30 Ile Ser Ala His Pro Ile Gly Ser Cys Lys Glu Gln Thr Ser Gly Ser 35 40 45 Val Tyr Gly Ala Ala Leu Ala Lys Ala Gly Phe Ile Val Ile Ala Phe 50 55 60 Asp Ala Ser Phe Gln Gly Ser Ser Gly Gly Glu Pro Arg Tyr Leu Glu 65 70 75 80 Asp Pro Thr Met Arg Val Lys Asp Phe Ser Ile Val Val Asp Tyr Leu 85 90 95 Thr Ser Leu Pro Tyr Val Asp Ala Gly Arg Ile Gly Val Leu Gly Ile 100 105 110 Cys Gly Gly Gly Gly Tyr Ala Ile Asn Ala Ala Met Thr Glu Arg Arg 115 120 125 Ile Lys Ala Ile Gly Thr Val Thr Gly Ala Asn Tyr Gly Arg Leu Met 130 135 140 Arg Glu Gly Phe Thr Ala Phe Asn Pro Ile Gly Ala Leu Glu Ala Met 145 150 155 160 Ala Gln Gln Arg Thr Asp Glu Ala Asn Gly Ala Lys Leu Arg Val Asp 165 170 175 Asp Leu Leu Pro Ser Ser Pro Asp Ala Ala Leu Glu Ala Gly Leu Thr 180 185 190 Glu Ile Asp Leu Phe Glu Ala Thr Glu Tyr Tyr Arg Ser Pro Arg Gly 195 200 205 Tyr Ala Pro Asn Gly Val Asn Arg Ser Leu Phe Ser His Gln Thr Val 210 215 220 Ala Val Gly Trp Asp Ala Phe His Leu Ala Glu Val Leu Leu Thr Gln 225 230 235 240 Pro Ile Met Val Val Val Gly Asp Arg Val Gly Ala Phe Gly Ala Tyr 245 250 255 Arg Asp Gly Cys Glu Ile Ile Gly Arg Ala Ala Ser Lys His Lys Glu 260 265 270 Leu Val Val Val Glu Gly Tyr Ser His Tyr Asp Leu Tyr Asp Lys Pro 275 280 285 Glu Pro Val Lys Gln Ala Leu Asp Lys Leu Ile Pro Phe Tyr Lys Thr 290 295 300 His Leu * 305 <210> 1496 <211> 309 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2363..3289) <400> 1496 Met Met Lys Ile Glu Pro Ser Ile Leu Pro Ser Leu Ala Trp Phe Ala 1 5 10 15 Leu Ile Val Arg Ala Gly Ser Phe Ser Arg Ala Val Ser Glu Met Gly 20 25 30 Ile Thr Leu Ala Ala Leu Ser Gln Asn Leu Lys Ser Leu Glu Glu Arg 35 40 45 Leu Asn Thr Lys Leu Ile Tyr Arg Thr Thr Arg Asn Ile Ser Leu Thr 50 55 60 Glu Glu Gly Gln Arg Leu Tyr Glu Val Leu Val Ser Ala Leu Gly Gln 65 70 75 80 Ile Asp Asp Ala Leu Lys Asp Val Gly Asp Thr Gln Leu Glu Pro Thr 85 90 95 Gly Leu Leu Arg Ile Asn Ser Ser Arg Val Ala Ala Arg Met Leu Val 100 105 110 Glu Pro His Ile Gly Glu Phe Leu Thr Arg Tyr Pro Lys Thr Lys Ile 115 120 125 Glu Leu Ile Met Asp Asp Gly Leu Ser Asn Ile Ile Ala Asp Gly Cys 130 135 140 Asp Val Gly Ile Arg Leu Glu Gln Gly Leu Asp Glu His Met Thr Ala 145 150 155 160 Val Pro Val Ser Pro Leu Ile Lys Leu Val Thr Val Ala Ser Pro Asp 165 170 175 Tyr Leu Lys Glu His Gly Ile Pro Glu Thr Pro Gln Glu Leu Ser Asn 180 185 190 His Asn Cys Leu Arg Leu Arg His Lys Ser Ser Gly Ala Leu Ser Ala 195 200 205 Trp Glu Phe Ser Lys Val Val Gly Gly Asn Glu Glu Phe Glu Ile Glu 210 215 220 Val Ser Gly Lys Tyr Ile Ser Asn Asp Asp Glu Ser Met Ile Arg Met 225 230 235 240 Ala Leu Asn Gly Thr Gly Ile Ile Gln His Leu Asp Phe Ala Ile Ala 245 250 255 Glu His Ile Asn Ala Gly Lys Leu Gln Pro Ile Leu Glu Asp Trp Ala 260 265 270 Val Ser Phe Pro Gly Phe Tyr Ile Tyr Val Ser Ser Arg Val Arg Met 275 280 285 Pro Ser Lys Val Arg Ala Phe Ile Asp Phe Met Val Glu Lys Arg Val 290 295 300 Lys Leu Glu Asn * 305 <210> 1497 <211> 119 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(3577..3933) <400> 1497 Met Asn Lys Asn Leu Ile Leu Ala Phe Ala Leu Phe Ser Leu Pro Val 1 5 10 15 Phe Ala Glu Glu Asp Leu Gly Pro Gly Lys Tyr Val Cys Asp Ile Arg 20 25 30 Ile Ser Ser Leu Asp Thr Ala Thr Gln Ile Leu Ser Lys Ser Ala Thr 35 40 45 Val Leu Asp Asn Gly Asn Asn Phe Ile Val Gln Met Pro Asn Gly Asp 50 55 60 Gln Leu Tyr Ser Pro Asp Leu Glu Asn Val Asp Asp Gly Ile Lys Gln 65 70 75 80 Lys Ala Thr Ile Gly Gly Val Thr Phe Ile Arg Arg Pro Thr Phe Asn 85 90 95 Asp Arg Phe Ile Val Glu Asp Gly Asn Thr Gly Phe Phe Tyr Lys Met 100 105 110 Arg Asn Cys Glu Lys Lys * 115 <210> 1498 <211> 192 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(4126..4701) <400> 1498 Met Gln Lys Val Lys Leu Asn Asn Gly Ile Glu Met Pro Leu Leu Gly 1 5 10 15 Phe Gly Val Phe Gln Met Thr Asp Ala Ala Glu Cys Glu Arg Ala Val 20 25 30 Ile Asp Ala Ile Asn Thr Gly Tyr Arg Leu Ile Asp Thr Ala Ala Ser 35 40 45 Tyr Gln Asn Glu Pro Gln Val Gly Asn Ala Leu Lys Gln Ser Gly Ile 50 55 60 Ala Arg Asn Glu Leu Phe Val Thr Thr Lys Leu Trp Leu Gln Asp Thr 65 70 75 80 Ser Tyr Glu Gly Ala Lys Ala Gln Phe Glu Arg Ser Leu Asn Arg Leu 85 90 95 Gln Leu Asp Tyr Val Asp Leu Tyr Leu Ile His Gln Pro Tyr Gly Asp 100 105 110 Val His Gly Ala Trp Arg Ala Met Glu Glu Leu Gln Gln Ala Gly Lys 115 120 125 Ile Arg Ala Ile Gly Val Ser Asn Phe His Pro Asp Arg Leu Ala Asp 130 135 140 Leu Ile Ala Phe Asn Asn Val Val Pro Ala Val Asn Gln Val Glu Val 145 150 155 160 Asn Pro Phe Asn Gln Gln Leu His Ala Val Pro Trp Met Gln Ser Arg 165 170 175 Gly Ile Gln Pro Glu Ala Trp Ala Pro Phe Ala Val Thr Gly Arg * 180 185 190 <210> 1499 <211> 4669 <212> DNA <213> Escherichia coli O157:H7 <400> 1499 gggaatcatt gactcgctgt aaaaaattat gcatatatta tatatgattg tcatgtcata 60 tcctgaaatt cctcttgtat cacttcatga ttttatattt tattaattaa cgattttatt 120 ttgtattagc tgaatggatt cagtcctata gggttatata tttattaata agacgattct 180 tatatttgga tacctaataa gagttaccac ttttaccggc tgtatattaa atgtatttct 240 cctgcttttg tttatatttt gagttgattt gagttcccgg atacatataa tgcgcaggta 300 ttagagactg gggggaaatg taatgataaa gttaagagtg ttaacttaaa ataagttttt 360 agtagtaact tgctatttta ttaccctctg aactacatac tcagatatgt ggttgccaat 420 gctatgcaaa atttttgaat ttttatatgc gatgaacagt aaccggaatg gcatttaatg 480 cgttgctgtt tatgcaatct tggttttatt tggatgtatt gctggagatt gtgatgaata 540 aaatatatcg gctaaagtgg aacaggtccc gtaactgttg gagcgtctgc tcggagctgg 600 ggagcagagt aaaaggaaaa aagtcccggg ctgttttaat tagcgcgata agtttatatt 660 catctctggt attcgccgat gatgtcatcg taaaccagga taaaactatt gattttggca 720 aagagaacca gagcatcgat taccgtatta cggtgacaga caatgccaat ctggtaatca 780 atgcgacaga tacttcccgt ccgcgtctga ctctcgcttc tggtggtggg ttggatatta 840 ccggaggaaa ggtaacaatc aatggcccac ttaacttttt gctgaaaggt acggggttcc 900 tgaatgtctc caatgctggc agcgagttat atgctgatga tttgtatgaa tcaaactcag 960 gcatgagaca cgatcgcggc tattttaatg tctccaacgg cggcaaaatc catgttaagg 1020 gcaccagccg tctgacctat ttgcagggaa atgtcagtgg tgaaggtagc caggtaaatt 1080 ccgaaacctt ctttatgggc gtttacggca gttacggtgg taatcagtac ctgtcagtta 1140 ataacggcgg tgaagttaat gccaggaagc aaattagcct gggctattat gatcaagtct 1200 ccgatacaac acttgctgtt tcggaaggtg gtaaaatttc tgcgcctact attagtttaa 1260 gcaccaactc tgagttagcg ttaggggcac aggaaggaag cgcagcgaag gcagcaggga 1320 ttattgatgc cgaaaaaatt gagtttgtgt gggcaaagac atccgagaag aaaatcacct 1380 taaaccacac ggataaagac gcgactattt ccgcggatat tgtcagtggc agcgagggcc 1440 tgggctatat caatgcgctc aatggcacga cttacttaac cggtgataac tctgccttta 1500 gtggtaaagt caaaattgag caaaatggcg ctttagggat cacccaaaat ataggtacag 1560 cagagatcaa caaccgcggg aaattacacc tgaaggctga cgatagcatg acctttgcca 1620 ataagatctc tggcaacggt acaataagta tcgacagtgg gacggtggag ttgaccggca 1680 ataactatgc attcagcgga tatattgatg ttgcttctgg tgctgtcgct gttatttctg 1740 aagacaagaa tatcggtcgt gcagagctgg atgtcgatgg caaattgcaa attaatgcca 1800 acaaagattg ggtatttgat aacgatcttg aaggtagagg cattgttgaa ataaacatgg 1860 ggaatcacga attctccttc gatgagtttg cttatacaga ctggttccag ggttcactgg 1920 cgttccagaa cacgacattt aatctggaaa agaatgctga gtttctgcag aaaggcggga 1980 tcactgcggg tcagggaagc ctggtaacag tgggtaaggg cgctcactcc attagcactt 2040 tgggattctc cggcggaacc gttgattttg gtgccctgac agcaggtgca cagatgacag 2100 aagggacggt caacgttagt aaaacgctgg atttgcgcgg cgagggtgtg attcaggttt 2160 ctgacagtga cgttgtccgc tcagtatctc gtgatattga ctctgcgtta tcgctcactg 2220 aagtcgatga tggtaacagc accattaagt tggttgatgc gcaaggtgcg gaagttctgg 2280 gcgatgcggg caatctgcaa ttgcaggata aaaatgggca aatcctctcc agcagcgccc 2340 aacgtgatat tcagcagaat gggcaaaaag cggccgtcgg cacttacgac tatcgtctga 2400 cgagtggggt aaacaatgac ggtctgtata ttggttacgg cctgacccag cttgatttac 2460 acgctaccga cagcgatgct ctggtgctga gctctaacgg taaaagcgag aatgccgccg 2520 atctcagcgc aaagattacc ggcagtggtg acctggcatt cagcagccag aagggtcaga 2580 ccgtatcgct ttctaacaaa gacaacgact ataccggtgt taccgatctg cgcagtggga 2640 cgcttttgtt gaataacgat aacgtgttgg gtaataccca tgaactgcgt ctggcggcag 2700 agactgaact ggacatgaat ggtcacagcc agaccgtggg cacgctcaat ggcagcgccg 2760 attcactgct gagcttaaat ggcggcagtc tgacggttac caacgggggc acttcaaccg 2820 gttcgttaac ggggagcgga gagctgaata ttcagggcgg cacgctggac atcgcgggcg 2880 ataacagcaa cctgacggcg aatgtgaaca ttgctaattc ggctaatgtc ctggtaagtc 2940 atgcgcaggg attgggtagc gcaaacgttg agaacaacgg taccctggcg ttgaataata 3000 gcgctgaaaa aagagcggct gcgtctgtga attacgccct gggcggcaat ctgaccaaca 3060 acggtacgct gatgaccgga atgtcaggac agcaagctgg caatgtgtta gtggtgaagg 3120 ggaactacca cggtaataac ggtcaactag taatgaatac ggtactgaat ggcgatgact 3180 cagtaaccga taaattggtt gtcgagggcg atactagcgg cacgactgcc gttacggtga 3240 ataacgctgg cggtacaggt gcgaaaaccc ttaacggtat cgaacttatc catgtagacg 3300 gtaagtctga gggcgaattt gttcaggctg ggcgtatcgt tgcgggggcg tatgactaca 3360 ctctcgcgcg tggacaaggg gcaaatagtg gtaactggta tctgaccagc ggcagtgatt 3420 ctcctgaact gcagccggag ccagacccga tgccgaatcc agagccaaac ccgaatccag 3480 agccgaaccc taacccgaca cctacgccgg gtccggatct gaatgtggat aatgacctgc 3540 gaccggaggc gggtagctac attgcgaacc ttgcagcagc gaataccatg ttcaccacgc 3600 gtctgcatga gcgtctgggt aatacgtact ataccgacat ggtgacgggt gagcagaaac 3660 aaaccactat gtggatgcgc catgaaggtg gtcataataa atggcgtgat ggcagcggcc 3720 agctgaaaac ccaaagcaat cgctatgttc tgcaactggg aggcgatgtc gcgcagtgga 3780 gccaaaacgg cagcgaccgc tggcatgttg gggtcatggc gggatatggc aacagcgaca 3840 gcaaaaccat ttcctcgcga accggttatc gtgcaaaagc gagtgtgaac ggatatagca 3900 caggcctcta tgccacctgg tatgccgatg acgagtcgcg taatggcgcg tatctcgaca 3960 gttgggcgca gtacagctgg tttgataaca cagtgaaagg ggatgactta caaagtgaat 4020 cctataaatc aaaaggattt accgcttcac tggaagctgg atacaaacac aaattagctg 4080 aatttaatgg cagccaggga acgcgtaatg aatggtatgt tcagccgcaa gcacaggtta 4140 cctggatggg agtcaaagcc gataagcacc gcgaaagcaa cggaaccctc gttcatagca 4200 acggtgatgg caatgttcaa acccgacttg gcgtaaaaac ctggctgaag agccaccata 4260 aaatggatga cggtaaatcc cgcgagttcc agccgtttgt agaagtgaac tggctacata 4320 acagtaagga tttcagcacc agtatggatg gcgtgtctgt cactcaggat ggagcccgaa 4380 atattgctga gataaaaacc ggggtggaag gacagctaaa tgccaacctg aatgtctggg 4440 ggaatgtggg cgttcaggtt gccgataggg gatataatga cacctctgca atggttggca 4500 ttaagtggca attctgatct gaataatgag taaaaggaga gagagccgaa cgggagataa 4560 ttcggctctc tgtgtcattt tcttgcagcc agctttatcc gtcagagtga agactcgcag 4620 atttagctgg cgcacaagat ttaatcaagg tgtgttcaat ggcttcgca 4669 <210> 1500 <211> 1328 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(534..4517) <400> 1500 Met Asn Lys Ile Tyr Arg Leu Lys Trp Asn Arg Ser Arg Asn Cys Trp 1 5 10 15 Ser Val Cys Ser Glu Leu Gly Ser Arg Val Lys Gly Lys Lys Ser Arg 20 25 30 Ala Val Leu Ile Ser Ala Ile Ser Leu Tyr Ser Ser Leu Val Phe Ala 35 40 45 Asp Asp Val Ile Val Asn Gln Asp Lys Thr Ile Asp Phe Gly Lys Glu 50 55 60 Asn Gln Ser Ile Asp Tyr Arg Ile Thr Val Thr Asp Asn Ala Asn Leu 65 70 75 80 Val Ile Asn Ala Thr Asp Thr Ser Arg Pro Arg Leu Thr Leu Ala Ser 85 90 95 Gly Gly Gly Leu Asp Ile Thr Gly Gly Lys Val Thr Ile Asn Gly Pro 100 105 110 Leu Asn Phe Leu Leu Lys Gly Thr Gly Phe Leu Asn Val Ser Asn Ala 115 120 125 Gly Ser Glu Leu Tyr Ala Asp Asp Leu Tyr Glu Ser Asn Ser Gly Met 130 135 140 Arg His Asp Arg Gly Tyr Phe Asn Val Ser Asn Gly Gly Lys Ile His 145 150 155 160 Val Lys Gly Thr Ser Arg Leu Thr Tyr Leu Gln Gly Asn Val Ser Gly 165 170 175 Glu Gly Ser Gln Val Asn Ser Glu Thr Phe Phe Met Gly Val Tyr Gly 180 185 190 Ser Tyr Gly Gly Asn Gln Tyr Leu Ser Val Asn Asn Gly Gly Glu Val 195 200 205 Asn Ala Arg Lys Gln Ile Ser Leu Gly Tyr Tyr Asp Gln Val Ser Asp 210 215 220 Thr Thr Leu Ala Val Ser Glu Gly Gly Lys Ile Ser Ala Pro Thr Ile 225 230 235 240 Ser Leu Ser Thr Asn Ser Glu Leu Ala Leu Gly Ala Gln Glu Gly Ser 245 250 255 Ala Ala Lys Ala Ala Gly Ile Ile Asp Ala Glu Lys Ile Glu Phe Val 260 265 270 Trp Ala Lys Thr Ser Glu Lys Lys Ile Thr Leu Asn His Thr Asp Lys 275 280 285 Asp Ala Thr Ile Ser Ala Asp Ile Val Ser Gly Ser Glu Gly Leu Gly 290 295 300 Tyr Ile Asn Ala Leu Asn Gly Thr Thr Tyr Leu Thr Gly Asp Asn Ser 305 310 315 320 Ala Phe Ser Gly Lys Val Lys Ile Glu Gln Asn Gly Ala Leu Gly Ile 325 330 335 Thr Gln Asn Ile Gly Thr Ala Glu Ile Asn Asn Arg Gly Lys Leu His 340 345 350 Leu Lys Ala Asp Asp Ser Met Thr Phe Ala Asn Lys Ile Ser Gly Asn 355 360 365 Gly Thr Ile Ser Ile Asp Ser Gly Thr Val Glu Leu Thr Gly Asn Asn 370 375 380 Tyr Ala Phe Ser Gly Tyr Ile Asp Val Ala Ser Gly Ala Val Ala Val 385 390 395 400 Ile Ser Glu Asp Lys Asn Ile Gly Arg Ala Glu Leu Asp Val Asp Gly 405 410 415 Lys Leu Gln Ile Asn Ala Asn Lys Asp Trp Val Phe Asp Asn Asp Leu 420 425 430 Glu Gly Arg Gly Ile Val Glu Ile Asn Met Gly Asn His Glu Phe Ser 435 440 445 Phe Asp Glu Phe Ala Tyr Thr Asp Trp Phe Gln Gly Ser Leu Ala Phe 450 455 460 Gln Asn Thr Thr Phe Asn Leu Glu Lys Asn Ala Glu Phe Leu Gln Lys 465 470 475 480 Gly Gly Ile Thr Ala Gly Gln Gly Ser Leu Val Thr Val Gly Lys Gly 485 490 495 Ala His Ser Ile Ser Thr Leu Gly Phe Ser Gly Gly Thr Val Asp Phe 500 505 510 Gly Ala Leu Thr Ala Gly Ala Gln Met Thr Glu Gly Thr Val Asn Val 515 520 525 Ser Lys Thr Leu Asp Leu Arg Gly Glu Gly Val Ile Gln Val Ser Asp 530 535 540 Ser Asp Val Val Arg Ser Val Ser Arg Asp Ile Asp Ser Ala Leu Ser 545 550 555 560 Leu Thr Glu Val Asp Asp Gly Asn Ser Thr Ile Lys Leu Val Asp Ala 565 570 575 Gln Gly Ala Glu Val Leu Gly Asp Ala Gly Asn Leu Gln Leu Gln Asp 580 585 590 Lys Asn Gly Gln Ile Leu Ser Ser Ser Ala Gln Arg Asp Ile Gln Gln 595 600 605 Asn Gly Gln Lys Ala Ala Val Gly Thr Tyr Asp Tyr Arg Leu Thr Ser 610 615 620 Gly Val Asn Asn Asp Gly Leu Tyr Ile Gly Tyr Gly Leu Thr Gln Leu 625 630 635 640 Asp Leu His Ala Thr Asp Ser Asp Ala Leu Val Leu Ser Ser Asn Gly 645 650 655 Lys Ser Glu Asn Ala Ala Asp Leu Ser Ala Lys Ile Thr Gly Ser Gly 660 665 670 Asp Leu Ala Phe Ser Ser Gln Lys Gly Gln Thr Val Ser Leu Ser Asn 675 680 685 Lys Asp Asn Asp Tyr Thr Gly Val Thr Asp Leu Arg Ser Gly Thr Leu 690 695 700 Leu Leu Asn Asn Asp Asn Val Leu Gly Asn Thr His Glu Leu Arg Leu 705 710 715 720 Ala Ala Glu Thr Glu Leu Asp Met Asn Gly His Ser Gln Thr Val Gly 725 730 735 Thr Leu Asn Gly Ser Ala Asp Ser Leu Leu Ser Leu Asn Gly Gly Ser 740 745 750 Leu Thr Val Thr Asn Gly Gly Thr Ser Thr Gly Ser Leu Thr Gly Ser 755 760 765 Gly Glu Leu Asn Ile Gln Gly Gly Thr Leu Asp Ile Ala Gly Asp Asn 770 775 780 Ser Asn Leu Thr Ala Asn Val Asn Ile Ala Asn Ser Ala Asn Val Leu 785 790 795 800 Val Ser His Ala Gln Gly Leu Gly Ser Ala Asn Val Glu Asn Asn Gly 805 810 815 Thr Leu Ala Leu Asn Asn Ser Ala Glu Lys Arg Ala Ala Ala Ser Val 820 825 830 Asn Tyr Ala Leu Gly Gly Asn Leu Thr Asn Asn Gly Thr Leu Met Thr 835 840 845 Gly Met Ser Gly Gln Gln Ala Gly Asn Val Leu Val Val Lys Gly Asn 850 855 860 Tyr His Gly Asn Asn Gly Gln Leu Val Met Asn Thr Val Leu Asn Gly ８６５ ８７０
８７５ ８８０ Ａｓｐ Ａｓｐ Ｓｅｒ Ｖａｌ Ｔｈｒ Ａｓｐ Ｌｙｓ Ｌｅｕ Ｖａｌ
Ｖａｌ Ｇｌｕ Ｇｌｙ Ａｓｐ Ｔｈｒ Ｓｅｒ Ｇｌｙ ８８５
８９０ ８９５ Ｔｈｒ Ｔｈｒ Ａｌａ Ｖａｌ Ｔｈｒ Ｖａｌ Ａｓｎ Ａｓｎ Ａｌａ
Ｇｌｙ Ｇｌｙ Ｔｈｒ Ｇｌｙ Ａｌａ Ｌｙｓ Ｔｈｒ ９００ ９０５
９１０ Ｌｅｕ Ａｓｎ Ｇｌｙ Ｉｌｅ Ｇｌｕ Ｌｅｕ Ｉｌｅ Ｈｉｓ Ｖａｌ
Ａｓｐ Ｇｌｙ Ｌｙｓ Ｓｅｒ Ｇｌｕ Ｇｌｙ Ｇｌｕ ９１５ ９２０
９２５ Ｐｈｅ Ｖａｌ Ｇｌｎ Ａｌａ Ｇｌｙ Ａｒｇ Ｉｌｅ Ｖａｌ Ａｌａ
Ｇｌｙ Ａｌａ Ｔｙｒ Ａｓｐ Ｔｙｒ Ｔｈｒ Ｌｅｕ ９３０ ９３５
９４０ Ａｌａ Ａｒｇ Ｇｌｙ Ｇｌｎ Ｇｌｙ Ａｌａ Ａｓｎ Ｓｅｒ Ｇｌｙ
Ａｓｎ Ｔｒｐ Ｔｙｒ Ｌｅｕ Ｔｈｒ Ｓｅｒ Ｇｌｙ ９４５ ９５０
９５５ ９６０ Ｓｅｒ Ａｓｐ Ｓｅｒ Ｐｒｏ Ｇｌｕ Ｌｅｕ Ｇｌｎ Ｐｒｏ Ｇｌｕ
Ｐｒｏ Ａｓｐ Ｐｒｏ Ｍｅｔ Ｐｒｏ Ａｓｎ Ｐｒｏ ９６５
９７０ ９７５ Ｇｌｕ Ｐｒｏ Ａｓｎ Ｐｒｏ Ａｓｎ Ｐｒｏ Ｇｌｕ Ｐｒｏ Ａｓｎ
Ｐｒｏ Ａｓｎ Ｐｒｏ Ｔｈｒ Ｐｒｏ Ｔｈｒ Ｐｒｏ ９８０ ９８５
９９０ Ｇｌｙ Ｐｒｏ Ａｓｐ Ｌｅｕ Ａｓｎ Ｖａｌ Ａｓｐ Ａｓｎ Ａｓｐ
Ｌｅｕ Ａｒｇ Ｐｒｏ Ｇｌｕ Ａｌａ Ｇｌｙ Ｓｅｒ ９９５ １０００
１００５ Ｔｙｒ Ｉｌｅ Ａｌａ Ａｓｎ Ｌｅｕ Ａｌａ Ａｌａ Ａｌａ Ａｓｎ
Ｔｈｒ Ｍｅｔ Ｐｈｅ Ｔｈｒ Ｔｈｒ Ａｒｇ Ｌｅｕ １０１０ １０１５
１０２０ Ｈｉｓ Ｇｌｕ Ａｒｇ Ｌｅｕ Ｇｌｙ Ａｓｎ Ｔｈｒ Ｔｙｒ Ｔｙｒ
Ｔｈｒ Ａｓｐ Ｍｅｔ Ｖａｌ Ｔｈｒ Ｇｌｙ Ｇｌｕ １０２５ １０３０
１０３５ １０４０ Ｇｌｎ Ｌｙｓ Ｇｌｎ Ｔｈｒ Ｔｈｒ Ｍｅｔ Ｔｒｐ Ｍｅｔ Ａｒｇ
Ｈｉｓ Ｇｌｕ Ｇｌｙ Ｇｌｙ Ｈｉｓ Ａｓｎ Ｌｙｓ １０４５
１０５０ １０５５ Ｔｒｐ Ａｒｇ Ａｓｐ Ｇｌｙ Ｓｅｒ Ｇｌｙ Ｇｌｎ Ｌｅｕ Ｌｙｓ
Ｔｈｒ Ｇｌｎ Ｓｅｒ Ａｓｎ Ａｒｇ Ｔｙｒ Ｖａｌ １０６０ １０６
５ １０７０ Ｌｅｕ Ｇｌｎ Ｌｅｕ Ｇｌｙ Ｇｌｙ Ａｓｐ Ｖａｌ Ａｌａ Ｇｌｎ
Ｔｒｐ Ｓｅｒ Ｇｌｎ Ａｓｎ Ｇｌｙ Ｓｅｒ Ａｓｐ １０７５ １０８０
１０８５ Ａｒｇ Ｔｒｐ Ｈｉｓ Ｖａｌ Ｇｌｙ Ｖａｌ Ｍｅｔ Ａｌａ Ｇｌｙ
Ｔｙｒ Ｇｌｙ Ａｓｎ Ｓｅｒ Ａｓｐ Ｓｅｒ Ｌｙｓ Thr Ile Ser Ser Arg Thr Gly Tyr Arg Ala Lys Ala Ser Val Asn Gly 1105 1110 1115 1120 Tyr Ser Thr Gly Leu Tyr Ala Thr Trp Tyr Ala Asp Asp Glu Ser Arg 1125 1130 1135 Asn Gly Ala Tyr Leu Asp Ser Trp Ala Gln Tyr Ser Trp Phe Asp Asn 1140 1145 1150 Thr Val Lys Gly Asp Asp Leu Gln Ser Glu Ser Tyr Lys Ser Lys Gly 1155 1160 1165 Phe Thr Ala Ser Leu Glu Ala Gly Tyr Lys His Lys Leu Ala Glu Phe 1170 1175 1180 Asn Gly Ser Gln Gly Thr Arg Asn Glu Trp Tyr Val Gln Pro Gln Ala 1185 1190 1195 1200 Gln Val Thr Trp Met Gly Val Lys Ala Asp Lys His Arg Glu Ser Asn 1205 1210 1215 Gly Thr Leu Val His Ser Asn Gly Asp Gly Asn Val Gln Thr Arg Leu 1220 1225 1230 Gly Val Lys Thr Trp Leu Lys Ser His His Lys Met Asp Asp Gly Lys 1235 1240 1245 Ser Arg Glu Phe Gln Pro Phe Val Glu Val Asn Trp Leu His Asn Ser 1250 1255 1260 Lys Asp Phe Ser Thr Ser Met Asp Gly Val Ser Val Thr Gln Asp Gly 1265 1270 1275 1280 Ala Arg Asn Ile Ala Glu Ile Lys Thr Gly Val Glu Gly Gln Leu Asn 1285 1290 1295 Ala Asn Leu Asn Val Trp Gly Asn Val Gly Val Gln Val Ala Asp Arg 1300 1305 1310 Gly Tyr Asn Asp Thr Ser Ala Met Val Gly Ile Lys Trp Gln Phe * 1315 1320 1325 <210> 1501 <211> 4593 <212> DNA <213> Escherichia coli O157:H7 <400> 1501 taagctcaca aacataaaat atcgctaatt ttgtttattt tgctgttttt tacgtgatga 60 atgtcacact tattattgct gcccgttttg tccatattta taaccatatt tttaatagct 120 gcctgaaata gagctgttta ttctgcataa aaatattcga aaattcttat tctctccagc 180 gcgctaattt gggcgaacac ttcctgacta ccctgcaatg aggctgaaat gatgaataaa 240 cgttttgtta tcaatatggt gtcttcgctg ttattaggcg ctgcgctaat ttctgcgccg 300 ctccaggcag cggaaaaagt cgtggtgaat atttctaaag tcgatggtat gccgtggttt 360 aatcgcatgg gcgaaggtgt ggttgaggcg ggtaaagcct ttggtgttaa tgcctcacag 420 gtggggcctt caagtactga tgctccgcaa caagttaaaa ttattgagga tttaatcgcc 480 cgtaaggtta atgcaattac tatcgtgcca aacgatgcca acgtgctgga accggtattc 540 aaaaaagcgc gagatgccgg aattgtggtt ctgaccaacg aatcccccgg tcagccaagt 600 gctaactggg atatcgaaat cattgataac gaaaaatttg ccgctgaata tgttgagcat 660 atggcgaaac gcatgggtgg caagggcggc tatgtgattt acgtgggtag tttgaccgtg 720 ccgcagcata acttatgggc tgacttgctg gtgaaatacc agaaagagca ttacccggat 780 atgcatgaag ttacccgccg catgccggtt gccgagagtg tggatgtctc acgtcgtact 840 acactggacc tgatgaaaac ctatcctgac ttgaaagcgg ttgtctcctt tggttcaaac 900 ggtccgattg gcgcgggacg tgcggtgaaa gagaaacggg cgaaaaataa agtcgcagtc 960 tatggcatga tgatcccttc acaggcggca tcactgatta aaagtggtga tatcaccgaa 1020 gggattactt acgatccggc ctctgcaggt tacgcactcg cagccgtcgc cagcacgttg 1080 ctgaagggtg aagagatcaa gcctggatta gaaatgcaga atctgggtaa ggccgacgta 1140 gatatggata agcgaattat ccgtttccat aaggtattac tggtcaacaa agacaatatc 1200 gactcacttt attaatccat ttcttcgggg cgaaagcccc gattcttatt gccaggggat 1260 gttatggaaa ccttcctttc ccttcgtcat atcaacaaaa cgtttcatgc cacgcgagcg 1320 ctgcgcgatg tttctctcga ctttatgtcg ggtgaagtgc actgccttgc cgggcaaaac 1380 ggctgtggta aatcgacgtt gattaaaatt atgtccggtg tttatcgccc ggatgaggga 1440 gcggaaatta cgcttggtgg gaaaaactgg tcaaagctga cacccgccgc ttcggtggcg 1500 caggggattc aggtgattta ttaggacctc tctttatttc ctaacctgag tgtctgggag 1560 aatatcgccg tgaatcacta tcaccacggt ctgtttgtta accgccgtcg tctgcgtgag 1620 gtggcgcagg cggcaatgac tagtattaac gtcacattgc cactggatac gctcgtttct 1680 gagctttcaa ttgcccgctg tcagctggtg gcaatttgcc gtgcactggc gcaggacgca 1740 cggttgatcg tgatggatga accaaccgct tcgctgaccc atcaggaagt gcaagggtta 1800 ttacaggtgg tgcatcaatt gcgtgaacgc gggatctgcg tggtctttgt cagtcatcgt 1860 ctggaagaag tgatggaagt ttccgaccgt atttcagtgc tgaaagatgg tgagctggtc 1920 gggacttttc cggctgcaga gatgaccaca aaacaactcg gtttcctgat gaccggccag 1980 gagtttgaat atcaggtgcg agagttgtgg cagggaaaat ccagcacccc ggtgctggag 2040 gtgcgtaatt taagtcgtca tggggaatat ctaaatatta acttgcgggt ggaagcgggc 2100 gaagtggtat cgattgttgg cctgcttggt gcggggcgca cggaattatg tctgagtctg 2160 tttggtatga cccgaccaga tgctggcgag atcctcatca acggccagct ggttacactg 2220 catagtaacc aggacgccat ccgccacggt attggttatg tttcggaaga tcgcatgtcg 2280 cgcggtttgg tgatggcgca atctattgaa gacaacatca ttagcactgt ttttcacaag 2340 gtaaaagatc gcttcggctt tctgagtgaa actaaagtgc gtgacctggt ggacaggcta 2400 atcaaggcat tgaccatcaa agtctctgat cctcatcttc cggtgaatac gctttctggt 2460 ggtaacgcgc agcgagtatc gatcgccaaa tggctggcga ttgggccacg actgttgatt 2520 ctcgatagcc cgacagtcgg tgttgatatc gccaacaaag caggaatata cggcattatc 2580 agcgatctgg cggctcatgg cattgcggta ttgatgatct gcgatgaaat tgaagaagcg 2640 tggtatcaaa gccaccggat tttggtaatg caaaaaggtc agatcaccca tagcttcctg 2700 cctgacagca gttctcaggc caggattgcg gaggtggtaa atggctgaac tgaaaaaacg 2760 ccatgaattc tggctggcat tactgattgt ggtgctgttt gttggccttg cctggcgcag 2820 cgacgagttt ctgacattcg gtaatttgta cgatctcgcc aataactatg ccatgttgac 2880 tattctcgcc tgtggtttgt ttgtggtgtt gatttccggt ggaattgata tttcgtttcc 2940 agcaatgacc atcattgcgc aatacggcat ggtgctgttg ctgcaaaaaa ttggtggcaa 3000 cttcgctgtc gcgtttgcac tggcaggctg catcggcatt ttacttggct taattaacgc 3060 cttactggtt aatcgcctac gggtgccttc tatcatcatc actatctcga cgctgaatat 3120 tttctatggc ctgctgttat ggttgagtaa aggtgtgtgg ctgtacgact ttccgccgtg 3180 gtttgagcag ggggttatgt tgttcaagta caccgatgct gatggctatg actatggcct 3240 tggtctgccg ctgatcgcca tgattacggt ggtgctgctg acagcgttta tcatgaattt 3300 caccagtgta gggcgcaaaa tttatgccct tggcgggaac cgcgaatcag ccagtcgcat 3360 cggctttagc gtgctgaaac tgcaactttt cgtctacggc tatatgggat tgatgtctgg 3420 cgctgcgggt gtagtgcagt cgtggacggt gatgactgtc gcccccgatt ctcttctggg 3480 ttatgagctg acagtactgg ctgcggtggt gcttggcggc actagtttgc tcggcgggcg 3540 cggcacgtta actggtactt tgctcggcgt ggtgttgttg gcagtgatgc aaaacgggct 3600 aaatttattg ggagtctcgt cttactggca aacattgatc accggcatca tcatcgttgc 3660 cagcattagc gccacggcgt ggagtcagca tcagaaccgg agcctgctat gaaaaaatcg 3720 tggcgtaata acgttgagtt ttacttgatc ggcctgctgg tgctaactgt tgccgcgttc 3780 agcattacta tgccggagat tttctggtcg ataagtaatt tccagtccgt cgcttcgcaa 3840 atgcccgtgc tgggcattct ggcgttggct atggcggtga ccatgctttg cggtggcatt 3900 aacttgtcaa ttatagccac tgctaacgcc tgttcactgg tgatggcgtg ggtggcgact 3960 cagtatccac cgggtattgc tacggttgtc gctacgttac tggcgggcgc tggcgcggcg 4020 gtgataatcg gtttatgtaa cggcgtattg attgctggta ttcgagtgtt gccaattctt 4080 gcaacgcttg ggatgatgac gttgctcaaa gggataaata ttctggtgac aggtggtagc 4140 gccattgcca attatccctc atgggtgctg tggttgaatc atgcgcaatg gttcggtatt 4200 ccgctaccga tgtggttgtt tgccgcagtg gcactggggc tgtggatatt gctggagaaa 4260 acgccgctcg gtaaagccat ttacctgatt gggtctaacg aacgagcaac actttactcc 4320 ggcattaaca ctcgtcgggt gctgatttgg gtttatgtca tttccgcctt gctttgtgcg 4380 gtagcggcat ttttgatgat gtcgaaactc aactcggcta aggcctctta tggcgaatcg 4440 tacttgctgg tgtcaatcct cgcggcagta ctcggcgggg ttaatccgga cggcggcagc 4500 gggcggataa ttggtatggt gctggcgctg tttcttctgc aaattattga aagcggcttc 4560 aatattctcg gtataagccc ctacctgacg atg 4593 <210> 1502 <211> 329 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(229..1215) <400> 1502 Met Met Asn Lys Arg Phe Val Ile Asn Met Val Ser Ser Leu Leu Leu 1 5 10 15 Gly Ala Ala Leu Ile Ser Ala Pro Leu Gln Ala Ala Glu Lys Val Val 20 25 30 Val Asn Ile Ser Lys Val Asp Gly Met Pro Trp Phe Asn Arg Met Gly 35 40 45 Glu Gly Val Val Glu Ala Gly Lys Ala Phe Gly Val Asn Ala Ser Gln 50 55 60 Val Gly Pro Ser Ser Thr Asp Ala Pro Gln Gln Val Lys Ile Ile Glu 65 70 75 80 Asp Leu Ile Ala Arg Lys Val Asn Ala Ile Thr Ile Val Pro Asn Asp 85 90 95 Ala Asn Val Leu Glu Pro Val Phe Lys Lys Ala Arg Asp Ala Gly Ile 100 105 110 Val Val Leu Thr Asn Glu Ser Pro Gly Gln Pro Ser Ala Asn Trp Asp 115 120 125 Ile Glu Ile Ile Asp Asn Glu Lys Phe Ala Ala Glu Tyr Val Glu His 130 135 140 Met Ala Lys Arg Met Gly Gly Lys Gly Gly Tyr Val Ile Tyr Val Gly 145 150 155 160 Ser Leu Thr Val Pro Gln His Asn Leu Trp Ala Asp Leu Leu Val Lys 165 170 175 Tyr Gln Lys Glu His Tyr Pro Asp Met His Glu Val Thr Arg Arg Met 180 185 190 Pro Val Ala Glu Ser Val Asp Val Ser Arg Arg Thr Thr Leu Asp Leu 195 200 205 Met Lys Thr Tyr Pro Asp Leu Lys Ala Val Val Ser Phe Gly Ser Asn 210 215 220 Gly Pro Ile Gly Ala Gly Arg Ala Val Lys Glu Lys Arg Ala Lys Asn 225 230 235 240 Lys Val Ala Val Tyr Gly Met Met Ile Pro Ser Gln Ala Ala Ser Leu 245 250 255 Ile Lys Ser Gly Asp Ile Thr Glu Gly Ile Thr Tyr Asp Pro Ala Ser 260 265 270 Ala Gly Tyr Ala Leu Ala Ala Val Ala Ser Thr Leu Leu Lys Gly Glu 275 280 285 Glu Ile Lys Pro Gly Leu Glu Met Gln Asn Leu Gly Lys Ala Asp Val 290 295 300 Asp Met Asp Lys Arg Ile Ile Arg Phe His Lys Val Leu Leu Val Asn 305 310 315 320 Lys Asp Asn Ile Asp Ser Leu Tyr * 325 <210> 1503 <211> 87 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1264..1524) <400> 1503 Met Glu Thr Phe Leu Ser Leu Arg His Ile Asn Lys Thr Phe His Ala 1 5 10 15 Thr Arg Ala Leu Arg Asp Val Ser Leu Asp Phe Met Ser Gly Glu Val 20 25 30 His Cys Leu Ala Gly Gln Asn Gly Cys Gly Lys Ser Thr Leu Ile Lys 35 40 45 Ile Met Ser Gly Val Tyr Arg Pro Asp Glu Gly Ala Glu Ile Thr Leu 50 55 60 Gly Gly Lys Asn Trp Ser Lys Leu Thr Pro Ala Ala Ser Val Ala Gln 65 70 75 80 Gly Ile Gln Val Ile Tyr * 85 <210> 1504 <211> 371 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1636..2748) <400> 1504 Met Thr Ser Ile Asn Val Thr Leu Pro Leu Asp Thr Leu Val Ser Glu 1 5 10 15 Leu Ser Ile Ala Arg Cys Gln Leu Val Ala Ile Cys Arg Ala Leu Ala 20 25 30 Gln Asp Ala Arg Leu Ile Val Met Asp Glu Pro Thr Ala Ser Leu Thr 35 40 45 His Gln Glu Val Gln Gly Leu Leu Gln Val Val His Gln Leu Arg Glu 50 55 60 Arg Gly Ile Cys Val Val Phe Val Ser His Arg Leu Glu Glu Val Met 65 70 75 80 Glu Val Ser Asp Arg Ile Ser Val Leu Lys Asp Gly Glu Leu Val Gly 85 90 95 Thr Phe Pro Ala Ala Glu Met Thr Thr Lys Gln Leu Gly Phe Leu Met 100 105 110 Thr Gly Gln Glu Phe Glu Tyr Gln Val Arg Glu Leu Trp Gln Gly Lys 115 120 125 Ser Ser Thr Pro Val Leu Glu Val Arg Asn Leu Ser Arg His Gly Glu 130 135 140 Tyr Leu Asn Ile Asn Leu Arg Val Glu Ala Gly Glu Val Val Ser Ile 145 150 155 160 Val Gly Leu Leu Gly Ala Gly Arg Thr Glu Leu Cys Leu Ser Leu Phe 165 170 175 Gly Met Thr Arg Pro Asp Ala Gly Glu Ile Leu Ile Asn Gly Gln Leu 180 185 190 Val Thr Leu His Ser Asn Gln Asp Ala Ile Arg His Gly Ile Gly Tyr 195 200 205 Val Ser Glu Asp Arg Met Ser Arg Gly Leu Val Met Ala Gln Ser Ile 210 215 220 Glu Asp Asn Ile Ile Ser Thr Val Phe His Lys Val Lys Asp Arg Phe 225 230 235 240 Gly Phe Leu Ser Glu Thr Lys Val Arg Asp Leu Val Asp Arg Leu Ile 245 250 255 Lys Ala Leu Thr Ile Lys Val Ser Asp Pro His Leu Pro Val Asn Thr 260 265 270 Leu Ser Gly Gly Asn Ala Gln Arg Val Ser Ile Ala Lys Trp Leu Ala 275 280 285 Ile Gly Pro Arg Leu Leu Ile Leu Asp Ser Pro Thr Val Gly Val Asp 290 295 300 Ile Ala Asn Lys Ala Gly Ile Tyr Gly Ile Ile Ser Asp Leu Ala Ala 305 310 315 320 His Gly Ile Ala Val Leu Met Ile Cys Asp Glu Ile Glu Glu Ala Trp 325 330 335 Tyr Gln Ser His Arg Ile Leu Val Met Gln Lys Gly Gln Ile Thr His 340 345 350 Ser Phe Leu Pro Asp Ser Ser Ser Gln Ala Arg Ile Ala Glu Val Val 355 360 365 Asn Gly * 370 <210> 1505 <211> 324 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2741..3712) <400> 1505 Met Ala Glu Leu Lys Lys Arg His Glu Phe Trp Leu Ala Leu Leu Ile 1 5 10 15 Val Val Leu Phe Val Gly Leu Ala Trp Arg Ser Asp Glu Phe Leu Thr 20 25 30 Phe Gly Asn Leu Tyr Asp Leu Ala Asn Asn Tyr Ala Met Leu Thr Ile 35 40 45 Leu Ala Cys Gly Leu Phe Val Val Leu Ile Ser Gly Gly Ile Asp Ile 50 55 60 Ser Phe Pro Ala Met Thr Ile Ile Ala Gln Tyr Gly Met Val Leu Leu 65 70 75 80 Leu Gln Lys Ile Gly Gly Asn Phe Ala Val Ala Phe Ala Leu Ala Gly 85 90 95 Cys Ile Gly Ile Leu Leu Gly Leu Ile Asn Ala Leu Leu Val Asn Arg 100 105 110 Leu Arg Val Pro Ser Ile Ile Ile Thr Ile Ser Thr Leu Asn Ile Phe 115 120 125 Tyr Gly Leu Leu Leu Trp Leu Ser Lys Gly Val Trp Leu Tyr Asp Phe 130 135 140 Pro Pro Trp Phe Glu Gln Gly Val Met Leu Phe Lys Tyr Thr Asp Ala 145 150 155 160 Asp Gly Tyr Asp Tyr Gly Leu Gly Leu Pro Leu Ile Ala Met Ile Thr 165 170 175 Val Val Leu Leu Thr Ala Phe Ile Met Asn Phe Thr Ser Val Gly Arg 180 185 190 Lys Ile Tyr Ala Leu Gly Gly Asn Arg Glu Ser Ala Ser Arg Ile Gly 195 200 205 Phe Ser Val Leu Lys Leu Gln Leu Phe Val Tyr Gly Tyr Met Gly Leu 210 215 220 Met Ser Gly Ala Ala Gly Val Val Gln Ser Trp Thr Val Met Thr Val 225 230 235 240 Ala Pro Asp Ser Leu Leu Gly Tyr Glu Leu Thr Val Leu Ala Ala Val 245 250 255 Val Leu Gly Gly Thr Ser Leu Leu Gly Gly Arg Gly Thr Leu Thr Gly 260 265 270 Thr Leu Leu Gly Val Val Leu Leu Ala Val Met Gln Asn Gly Leu Asn 275 280 285 Leu Leu Gly Val Ser Ser Tyr Trp Gln Thr Leu Ile Thr Gly Ile Ile 290 295 300 Ile Val Ala Ser Ile Ser Ala Thr Ala Trp Ser Gln His Gln Asn Arg 305 310 315 320 Ser Leu Leu * <210> 1506 <211> 4021 <212> DNA <213> Escherichia coli O157:H7 <400> 1506 cgcacaacgc cgccacttcc gtgagcgatc gcgcttcgct aattaacagc ttttcggctt 60 cgcgcacccg ctggcgatgg attgcttctg ttaacgtcag atgaaacacc cgccggtaga 120 cgcgcccaag ataatcggca ttgcagtaca gctcgcgggc cagaagcgcc gtagaaagcg 180 ggcgatgata ttgcgtgcgg atcagtttct gcgctttcca ggcaagggtg gtgcctgcgc 240 catcggcctg ttcatcaaga cgcgcgtcac gggtgagctg ctgcaaaatg agcagcacaa 300 taaactccag cgccggagtg cgttgatgct tttcctgttc gcttaagaac tggcgaaaca 360 gggccaccag cgcctgcgga tcgacaacct tcgtttgttg cggcacgcta agatgagtaa 420 gccagcgagg gtcgttgtcc ggcgctttaa cctcaaaatg cagccagtaa aatttgagat 480 cggcgggaaa atcctccacc ccaacatgtt gtcggttcgg ccagagtaat aaactctctc 540 ccgcatcgac cagaaatatc cgttcttctt cctgaatcgt taatcgacct ttttcgacaa 600 agataatttc ccatgactcc agccgccttg cagaatgcct ccctacgcca cgggaaataa 660 ataatccacc attttgcact ttaatcggta acgtcatgga taattcgagc attgatatgt 720 aatttcccgc ttattcatta atgattaaac acattacctt ttgattatta atcaaaaaca 780 ttaatttcac ctgatccatt tcacactttt aaattcaggt cggaatcgtc accttttttt 840 actcttttct cgccttgttg atattcccgt tcacggcaga attaatcagg tcatttcaat 900 aaaactaaaa attgctccct attcacgagg aatatctatg acctctacac cgattactac 960 cgctgatatc gctaaaggta aaattgacga tgcgttatct gtacgggaaa aaataggcta 1020 cggcctgggt gacgcaggcg gcaccgtaat aacttgcctg atcatgaatt ttctcacctt 1080 tttctacacc gacgtttttg gattaactcc ggcgctggtt ggcacgctgt ttattgcact 1140 gcgcgtgttt gatgccatct ccgacccggt gatgggcgtc attgccgacc ggacgcaaag 1200 ccgatggggg cgctttcgtc cgtggcagct atggattgcc attcccatcg gcattatcgg 1260 catcctgacg ttcaccgtgc cagatgccag catgggagta aaaatcgcct gggcgttcgg 1320 tacttacctg ctcctttcag tcggttatac cgccatcaac gtaccgtact gcgcgcggat 1380 caacaccatg accacccgcc acaatgaagt gatctcctgc cagtcctggc gattcgttct 1440 ctgcggcgta gcgggatttc tggtttcggt aggcttaccg tggatggtag ctctcttcgg 1500 tcagggcaac gctgcacgcg gctatcaact gggcgtcggg gtattgtgcg ccattgccgt 1560 ggtgatgttc ctgtgctgtt tcttctgggt tcgtgaacgg gtgccgctct ccacaatggg 1620 gaaatttacc ctgcgcgaac atcttgccgg gctgcggaac aacgaccaac tgctgctgat 1680 gctggtcatg tctttcctgc tgattaacgt ctttaacatt cgcggcggtg ggtatatgta 1740 cttcattacc tacgtcttac aaggcagcac gggctacacg tcgctgttct tcaccatggt 1800 caccttcgcc tccattatcg gctcggtgat tgtcagcccg ttaacgcggc gtttcgatac 1860 cgtcaaaatt tattactaca ccaacctgct cctcgctgca ctggcggtgt tgatgtggtt 1920 cctgccctcc ggcccggctt atcaaacgct gtggctggcg gtgatcctcg gtaatggcgt 1980 gattcttggc ttcacattgc cactgcactt ctcattgatg gcctttgccg atgactacgg 2040 cgagtggaaa acccacgtac gttcttccgg catgaacttc gccttcaatc tgtttttcat 2100 caagctggcc tgggcctcca gcgccgggat catcagcctg ctgtttattt ttgtcgccta 2160 ccagcctggc gtggaaaacc agaccgccag ttcgcttggc gggatcgcgg cgatggaaac 2220 attactgcct gcgctattcc acctgctgct ggcaggggcg atccgctttt gcaaactcaa 2280 taatcctatg atgtcacgca tagctaccga cctgcgtcag cgtcatgtac agccttaagg 2340 agcacaagat gaacatttcg gaagtcgatc tgcataaact gacggtcagc gatccgttcc 2400 tcggtcagta ccaacaactg gtccgcgacg tggtgattcc ttatcagtgg gatgccttga 2460 acgatcgtat cccagaagcg gaacccagcc atgcgattga aaactttcgc attgccgccg 2520 gacttcagga gggtgaattt tacgggatgg tgtttcagga cagcgacgtc gccaaatggc 2580 tggaagcggt agcctggtcg ctgtgccaga agccggacgc cgaactggaa aaaaccgccg 2640 acgaggtaat cgaactgatc gcctccgccc aatgcgaaga cggctatctc aatacttact 2700 ttacggtaaa agcacccgaa gaacgctgga gcaatctggc ggagtgtcat gaactttact 2760 gcgcaggtca tctgattgaa gccggagtcg ccttcttcca ggccacggga aaacggcgct 2820 tgctgggggt cgtttgccgc ctggccgatc atatcgacag cgtatttggt ccagatgaaa 2880 gtaagttaca cggttatcct ggtcacccgg aaattgaact ggcactaatg cgcctgtatg 2940 aagtgactga agagccgcgc tacctggcgc tgacgaacta ttttgtcgaa cagcgtggtg 3000 cgcaaccgca ctattacgac caggaatatg aaaagcgcgg gcagacatcg cactggcaca 3060 cctacggccc ggcgtggatg gtgaaagaca aagcctacag ccaggcacat ttgccccttg 3120 cgcaacagca aaccgccatc ggtcacgcgg tacgttttgt ctatctgatg accggcgtcg 3180 cgcatctcgc gcgtttaagt cacgatgaca gcaagcgtca ggactgcctg cggctgtgga 3240 acaatatggc ccagcgtcag ttatatatta ccggcggcat cggctcacaa agcagcggcg 3300 aagcgttcag cagcgattac gatctgccga atgacacggt ttacgccgaa agttgtgctt 3360 ccatcggcct gatgatgttc gcccgacgaa tgctggaaat ggaaggcgac agtcaatatg 3420 ccgatgtgat ggagcgcgca ctgtacaaca ctgtgctcgg cggcatggca ttggatggca 3480 aacatttctt ctatgtgaat ccactggaag tacatccaaa atcgctgaaa ttcaaccata 3540 tctacgatca cgttaaaccg atccgccagc gttggtttgg ctgcgcttgt tgtccgccaa 3600 atatcgcccg cgtgctgacc tcgattggtc attatctcta cacgccgcgt gaagatgcgt 3660 tgtatatcaa catctacgca ggaaacagca tggaagtgcc ggtagaaaat ggcacgctgc 3720 gcctgcgggt tagcgggaac tatccgtggc aggagcaggt gacgattgcg gttgaatcgc 3780 cccagccggt acgtcatacg ctggctttac gtctgccgga ctggtgcaca cagccgcaga 3840 tcatattgaa tggggaagag gtcgagcagg atattcgtaa agggtatttg cacattaccc 3900 gcgaatggca ggagggcgat acgctgaatc tgactttgcc gatgccggta cgccgcgttt 3960 acggtaaccc gctggtgcgt cacgtcgccg gaaaagtggc gattcagcgc ggcccgctgg 4020 t 4021 <210> 1507 <211> 467 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(938..2338) <400> 1507 Met Thr Ser Thr Pro Ile Thr Thr Ala Asp Ile Ala Lys Gly Lys Ile 1 5 10 15 Asp Asp Ala Leu Ser Val Arg Glu Lys Ile Gly Tyr Gly Leu Gly Asp 20 25 30 Ala Gly Gly Thr Val Ile Thr Cys Leu Ile Met Asn Phe Leu Thr Phe 35 40 45 Phe Tyr Thr Asp Val Phe Gly Leu Thr Pro Ala Leu Val Gly Thr Leu 50 55 60 Phe Ile Ala Leu Arg Val Phe Asp Ala Ile Ser Asp Pro Val Met Gly 65 70 75 80 Val Ile Ala Asp Arg Thr Gln Ser Arg Trp Gly Arg Phe Arg Pro Trp 85 90 95 Gln Leu Trp Ile Ala Ile Pro Ile Gly Ile Ile Gly Ile Leu Thr Phe 100 105 110 Thr Val Pro Asp Ala Ser Met Gly Val Lys Ile Ala Trp Ala Phe Gly 115 120 125 Thr Tyr Leu Leu Leu Ser Val Gly Tyr Thr Ala Ile Asn Val Pro Tyr 130 135 140 Cys Ala Arg Ile Asn Thr Met Thr Thr Arg His Asn Glu Val Ile Ser 145 150 155 160 Cys Gln Ser Trp Arg Phe Val Leu Cys Gly Val Ala Gly Phe Leu Val 165 170 175 Ser Val Gly Leu Pro Trp Met Val Ala Leu Phe Gly Gln Gly Asn Ala 180 185 190 Ala Arg Gly Tyr Gln Leu Gly Val Gly Val Leu Cys Ala Ile Ala Val 195 200 205 Val Met Phe Leu Cys Cys Phe Phe Trp Val Arg Glu Arg Val Pro Leu 210 215 220 Ser Thr Met Gly Lys Phe Thr Leu Arg Glu His Leu Ala Gly Leu Arg 225 230 235 240 Asn Asn Asp Gln Leu Leu Leu Met Leu Val Met Ser Phe Leu Leu Ile 245 250 255 Asn Val Phe Asn Ile Arg Gly Gly Gly Tyr Met Tyr Phe Ile Thr Tyr 260 265 270 Val Leu Gln Gly Ser Thr Gly Tyr Thr Ser Leu Phe Phe Thr Met Val 275 280 285 Thr Phe Ala Ser Ile Ile Gly Ser Val Ile Val Ser Pro Leu Thr Arg 290 295 300 Arg Phe Asp Thr Val Lys Ile Tyr Tyr Tyr Thr Asn Leu Leu Leu Ala 305 310 315 320 Ala Leu Ala Val Leu Met Trp Phe Leu Pro Ser Gly Pro Ala Tyr Gln 325 330 335 Thr Leu Trp Leu Ala Val Ile Leu Gly Asn Gly Val Ile Leu Gly Phe 340 345 350 Thr Leu Pro Leu His Phe Ser Leu Met Ala Phe Ala Asp Asp Tyr Gly 355 360 365 Glu Trp Lys Thr His Val Arg Ser Ser Gly Met Asn Phe Ala Phe Asn 370 375 380 Leu Phe Phe Ile Lys Leu Ala Trp Ala Ser Ser Ala Gly Ile Ile Ser 385 390 395 400 Leu Leu Phe Ile Phe Val Ala Tyr Gln Pro Gly Val Glu Asn Gln Thr 405 410 415 Ala Ser Ser Leu Gly Gly Ile Ala Ala Met Glu Thr Leu Leu Pro Ala 420 425 430 Leu Phe His Leu Leu Leu Ala Gly Ala Ile Arg Phe Cys Lys Leu Asn 435 440 445 Asn Pro Met Met Ser Arg Ile Ala Thr Asp Leu Arg Gln Arg His Val 450 455 460 Gln Pro * 465 <210> 1508 <211> 3823 <212> DNA <213> Escherichia coli O157:H7 <400> 1508 gcggatgttg cagcagcgga aaaagcgaaa ctgaagctta tcgcggagaa aacgaaaaaa 60 ggctatgtgg aaaatgcttc agcaaacgtg catatccccc ccatcaccaa agccactcct 120 gaagttgaaa cttcccctga gagtaaaaac caacgcccgt ggctggctga tgatgcagtt 180 attccggtaa ctgacgatat taaccgattt gcttttcctc atcgctctcg ccccagagag 240 atcaattatc tgcgcaaaga cggtgagata tggaagcgta ttgcagataa caccagggca 300 tatgatcccg acaacaatta ccgctcttat cctgaaaact ggcagcaggc ttttgctgag 360 ttacaaaggc gaattctgga taatcaacag acagggagtg cgcaatctga tgcagcattg 420 ctctggagtt tttggaactc ttactctgca gatgaactgg tcgatgactt agtcattcgc 480 tgtggtctgg aaagcgccgt tgaaatcgtc ctttttgccc ttcaactcaa atataaacca 540 gtaaaaggcg cagtaaccac catcattcca cctaatcacg aagcagaatc gctacctagt 600 tagcatcaac gtctatgtca tcatctttca ctcgcttcag aagatgagtg gcaacgctgt 660 gtagataaag tactcaccgc cattccgacg ctatcccccg cacggcaacc ttttgcggcg 720 ttactgctcc ctgaacgccc ggatatcgcc catgctatag atctacgcta tgcagaccaa 780 aacgtcccgg cgatgacctg gttaagactg gtgataaccg atgatactgc tctgagtaca 840 gtggaaaaat acgacttccc accgttgtat cgtgattttc gtaattttcg cgcttatctg 900 gcaatgttgt tggcaaataa tggggtgcgc ggtgtaagcc ggatacttct tgagtttacg 960 gaagaccatt ctgacaatcc cacttatctc ttcgaacgca tcagcgagac tgaaaatctt 1020 gtcaaatggc tatggaaaac gaatcacccg gatgcgattc aaattctgat cctcggtgta 1080 attggtaaga aaaagcacct ggaatactta agcaaggcca gtcaaaagca tcccgctgcg 1140 gctattgcgg cttatgctac tttgctggca atacatgaag ataaagagtg gcgtaaagcg 1200 cttgtcaaac tgattaccgc cacgccagag ttagtatgcg acgtcattcc ctgggttaat 1260 gctaaagcgg caggcatctt atctgaatgt cgtccgcagt cagtcgctga agaatgtgaa 1320 tatgccactg tggatatgtt gccggagctg cttgtttcgc cgccctggat gaccaaagag 1380 aaaaagaaaa atacgcctgt gtttgatctt ccagtgcttc cagttccttc tgtttctgat 1440 gtcactccag agattaccaa aaaactgacc cgtacttacc ttgtcaccca cttccagcaa 1500 atagcccaac agcaggcgac aaaacaaaca ttgtttaccg acctgccgcc gatcaaaaaa 1560 gcaagctggg agaaacactt aataccgctt acaccggagc aacaaatact gtggcatctt 1620 ggttttgaaa aatggcggga gagcggagaa aaaatatacg aaaaaattcc ggcgccacaa 1680 agcgccgttg atgccctgct acgcttcgat tttccagcac tcaatgctga atttgtgcat 1740 tatcataaca atgcatacaa aagctggaat ctcattgccc tctgttacct gcctggtcaa 1800 caggccattt cttttcttaa ccagatagtc aaagaagata actactctgg tgagggaaat 1860 attctggcaa tttttggtag cgccgccata cctgcattta tggcctgcct gcaacgtgat 1920 ccacgacgtc tgtgcttctt cccctttttc ctcggtgtca gtgaactggc cttaccgatg 1980 gcgcaacaat tacagaaaaa aatgtcttat gaagatgcgc gaaactggct aactgattat 2040 ccacgccatg ccgccgccgg gctgcttcct gtggccctgg gcaaaaaagg aaaagatcgt 2100 gattgtgccc gccaggcgct tcgtctgctg gtgaatttaa accagcgaga aacgattgag 2160 gaaatcgcgc aaggatataa tcaacctgat gttttagctg cgctggcaac attgttcgat 2220 agcgacccac tggaagaata tcccgctaaa atcgccccac tgcccggctt ttatcagttc 2280 accttgtggc gcagaccacg gcttaaaagt aacaacctgc ctctgtcaga tgacgctatg 2340 cgccacctcg gcactatgct gagctttcct cgcgacatta ccgcctacgc tgggctggat 2400 atcattagag aaatcttcac ccgcgaatca ctggctgaat ttggctggga tctgtatccc 2460 gcctggacag aagctggcgc acccgcaaaa gaaaactggg catttacttc gcttgggatt 2520 ttaggcaatg acgacaccgc gcgtaaatta accccgctta tccgcgcctg gcctggggaa 2580 tcccagcata aacgggcggt gtccgggctg gatgtattag ctgatattgg cagcgatgtt 2640 gcgctaatgc tgcttaatgg catcgcgcga aaaattaaat tcaaagcatt acaggaacat 2700 gcccgcgaga aaatcaacat agttgctgaa aaccgtgggc tgactatggc tgaactggaa 2760 gaccgcctgg ctccagattt agggcttgat agcagtggct cgctgatact ggatttcggc 2820 ccccgcaaat tcaccgttgg ttttgacgaa accttaaaac ctgtagtgtg cgatgcaaac 2880 ggcaaagtcc tgaaagattt acctaagcca aaccagagcg atgaaaaaac tcaggcaact 2940 gacgcggtta atctcttcaa acagttgaaa aaagatgtac gcgccatagc cagccagcag 3000 attgatcgtc tggaacaggc tatgtgccag cgcagacgct ggacggcaga gcagttccgc 3060 ctgtttctgg tggagcatcc gctggtacgt cacttaaccc gacggctgtt atggggggtt 3120 tataacgatg aaaacgccct tatcacctgt tttcgcgtgg cagaagacag cacttacagc 3180 gatgcgcagg atgagttatt cacgctgcca gcaggaaaca tcggtattcc gcatgtgctg 3240 gaaatatccc ctgaatccgc cgctgcattc aggcaaattt acgctgatta cgaactgctt 3300 ccccctttcc aacagctcga gcgaggtagc tatcaccttg ctgataatga acgtaatact 3360 cacgaactga cacgctggca aggacggctt tgccaggccg gacgcattgt cgggctggaa 3420 cgcagaggct ggcaacgtct ggaagaaagc ggcagcgttt atgcgatgcg caaaacaacc 3480 cctcatggcg atctcgaact tgaaacggaa cctttttcat taatttatgg tgaaacgggg 3540 tatggcgacc agcacccggt tgaaagcgta aaaatcacct cgccagatga tcgctacggt 3600 aaacaatcct cactcacttt ctccatgctc gacgacatca ccgccagcga gctgattaac 3660 gacattgaat cactgtttga ttaaaaggat ttaacaatga aaacctatat ttatcaggac 3720 gaaaaatcac ataaattctg ggcggtggag cagcagggaa acgagctgca tattaactgg 3780 ggtaaagtcg gtaccaacgg gcaaagtcag gtaaaaagct ttg 3823 <210> 1509 <211> 948 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(841..3684) <400> 1509 Val Glu Lys Tyr Asp Phe Pro Pro Leu Tyr Arg Asp Phe Arg Asn Phe 1 5 10 15 Arg Ala Tyr Leu Ala Met Leu Leu Ala Asn Asn Gly Val Arg Gly Val 20 25 30 Ser Arg Ile Leu Leu Glu Phe Thr Glu Asp His Ser Asp Asn Pro Thr 35 40 45 Tyr Leu Phe Glu Arg Ile Ser Glu Thr Glu Asn Leu Val Lys Trp Leu 50 55 60 Trp Lys Thr Asn His Pro Asp Ala Ile Gln Ile Leu Ile Leu Gly Val 65 70 75 80 Ile Gly Lys Lys Lys His Leu Glu Tyr Leu Ser Lys Ala Ser Gln Lys 85 90 95 His Pro Ala Ala Ala Ile Ala Ala Tyr Ala Thr Leu Leu Ala Ile His 100 105 110 Glu Asp Lys Glu Trp Arg Lys Ala Leu Val Lys Leu Ile Thr Ala Thr 115 120 125 Pro Glu Leu Val Cys Asp Val Ile Pro Trp Val Asn Ala Lys Ala Ala 130 135 140 Gly Ile Leu Ser Glu Cys Arg Pro Gln Ser Val Ala Glu Glu Cys Glu 145 150 155 160 Tyr Ala Thr Val Asp Met Leu Pro Glu Leu Leu Val Ser Pro Pro Trp 165 170 175 Met Thr Lys Glu Lys Lys Lys Asn Thr Pro Val Phe Asp Leu Pro Val 180 185 190 Leu Pro Val Pro Ser Val Ser Asp Val Thr Pro Glu Ile Thr Lys Lys 195 200 205 Leu Thr Arg Thr Tyr Leu Val Thr His Phe Gln Gln Ile Ala Gln Gln 210 215 220 Gln Ala Thr Lys Gln Thr Leu Phe Thr Asp Leu Pro Pro Ile Lys Lys 225 230 235 240 Ala Ser Trp Glu Lys His Leu Ile Pro Leu Thr Pro Glu Gln Gln Ile 245 250 255 Leu Trp His Leu Gly Phe Glu Lys Trp Arg Glu Ser Gly Glu Lys Ile 260 265 270 Tyr Glu Lys Ile Pro Ala Pro Gln Ser Ala Val Asp Ala Leu Leu Arg 275 280 285 Phe Asp Phe Pro Ala Leu Asn Ala Glu Phe Val His Tyr His Asn Asn 290 295 300 Ala Tyr Lys Ser Trp Asn Leu Ile Ala Leu Cys Tyr Leu Pro Gly Gln 305 310 315 320 Gln Ala Ile Ser Phe Leu Asn Gln Ile Val Lys Glu Asp Asn Tyr Ser 325 330 335 Gly Glu Gly Asn Ile Leu Ala Ile Phe Gly Ser Ala Ala Ile Pro Ala 340 345 350 Phe Met Ala Cys Leu Gln Arg Asp Pro Arg Arg Leu Cys Phe Phe Pro 355 360 365 Phe Phe Leu Gly Val Ser Glu Leu Ala Leu Pro Met Ala Gln Gln Leu 370 375 380 Gln Lys Lys Met Ser Tyr Glu Asp Ala Arg Asn Trp Leu Thr Asp Tyr 385 390 395 400 Pro Arg His Ala Ala Ala Gly Leu Leu Pro Val Ala Leu Gly Lys Lys 405 410 415 Gly Lys Asp Arg Asp Cys Ala Arg Gln Ala Leu Arg Leu Leu Val Asn 420 425 430 Leu Asn Gln Arg Glu Thr Ile Glu Glu Ile Ala Gln Gly Tyr Asn Gln 435 440 445 Pro Asp Val Leu Ala Ala Leu Ala Thr Leu Phe Asp Ser Asp Pro Leu 450 455 460 Glu Glu Tyr Pro Ala Lys Ile Ala Pro Leu Pro Gly Phe Tyr Gln Phe 465 470 475 480 Thr Leu Trp Arg Arg Pro Arg Leu Lys Ser Asn Asn Leu Pro Leu Ser 485 490 495 Asp Asp Ala Met Arg His Leu Gly Thr Met Leu Ser Phe Pro Arg Asp 500 505 510 Ile Thr Ala Tyr Ala Gly Leu Asp Ile Ile Arg Glu Ile Phe Thr Arg 515 520 525 Glu Ser Leu Ala Glu Phe Gly Trp Asp Leu Tyr Pro Ala Trp Thr Glu 530 535 540 Ala Gly Ala Pro Ala Lys Glu Asn Trp Ala Phe Thr Ser Leu Gly Ile 545 550 555 560 Leu Gly Asn Asp Asp Thr Ala Arg Lys Leu Thr Pro Leu Ile Arg Ala 565 570 575 Trp Pro Gly Glu Ser Gln His Lys Arg Ala Val Ser Gly Leu Asp Val 580 585 590 Leu Ala Asp Ile Gly Ser Asp Val Ala Leu Met Leu Leu Asn Gly Ile 595 600 605 Ala Arg Lys Ile Lys Phe Lys Ala Leu Gln Glu His Ala Arg Glu Lys 610 615 620 Ile Asn Ile Val Ala Glu Asn Arg Gly Leu Thr Met Ala Glu Leu Glu 625 630 635 640 Asp Arg Leu Ala Pro Asp Leu Gly Leu Asp Ser Ser Gly Ser Leu Ile 645 650 655 Leu Asp Phe Gly Pro Arg Lys Phe Thr Val Gly Phe Asp Glu Thr Leu 660 665 670 Lys Pro Val Val Cys Asp Ala Asn Gly Lys Val Leu Lys Asp Leu Pro 675 680 685 Lys Pro Asn Gln Ser Asp Glu Lys Thr Gln Ala Thr Asp Ala Val Asn 690 695 700 Leu Phe Lys Gln Leu Lys Lys Asp Val Arg Ala Ile Ala Ser Gln Gln 705 710 715 720 Ile Asp Arg Leu Glu Gln Ala Met Cys Gln Arg Arg Arg Trp Thr Ala 725 730 735 Glu Gln Phe Arg Leu Phe Leu Val Glu His Pro Leu Val Arg His Leu 740 745 750 Thr Arg Arg Leu Leu Trp Gly Val Tyr Asn Asp Glu Asn Ala Leu Ile 755 760 765 Thr Cys Phe Arg Val Ala Glu Asp Ser Thr Tyr Ser Asp Ala Gln Asp 770 775 780 Glu Leu Phe Thr Leu Pro Ala Gly Asn Ile Gly Ile Pro His Val Leu 785 790 795 800 Glu Ile Ser Pro Glu Ser Ala Ala Ala Phe Arg Gln Ile Tyr Ala Asp 805 810 815 Tyr Glu Leu Leu Pro Pro Phe Gln Gln Leu Glu Arg Gly Ser Tyr His 820 825 830 Leu Ala Asp Asn Glu Arg Asn Thr His Glu Leu Thr Arg Trp Gln Gly 835 840 845 Arg Leu Cys Gln Ala Gly Arg Ile Val Gly Leu Glu Arg Arg Gly Trp 850 855 860 Gln Arg Leu Glu Glu Ser Gly Ser Val Tyr Ala Met Arg Lys Thr Thr 865 870 875 880 Pro His Gly Asp Leu Glu Leu Glu Thr Glu Pro Phe Ser Leu Ile Tyr 885 890 895 Gly Glu Thr Gly Tyr Gly Asp Gln His Pro Val Glu Ser Val Lys Ile 900 905 910 Thr Ser Pro Asp Asp Arg Tyr Gly Lys Gln Ser Ser Leu Thr Phe Ser 915 920 925 Met Leu Asp Asp Ile Thr Ala Ser Glu Leu Ile Asn Asp Ile Glu Ser 930 935 940 Leu Phe Asp * 945 <210> 1510 <211> 3751 <212> DNA <213> Escherichia coli O157:H7 <400> 1510 ctgacactga gcgccgggca taagcagggc aagagcggtg agaatgacac tcgctttggc 60 ctggaagtta actaccgaat tggcgaacct ttggcgaaac aactcgatac ggatagcatt 120 cgcgagcgtc gggtactggc aggcagccgc tatgacctgg ttgagcgtaa taacaacatc 180 gttcttgagt accgcaaatc tgaagtgatc cgtattgctc tgcctgagcg tattgaaggt 240 aagggcggtc agacactttc cctggggctt gtggtcagca aagcaactca cggactgaaa 300 aatgtgcagt gggaagcgcc gtcattactg gctgaaggtg gcaaaattac cggtcagggt 360 agtcagtggc aagtaacgct cccggcttat cgtccaggca aagacaatta ttatgcgatt 420 tcagcagttg cctacgataa caaaggcaat acctcaaaac gcgtgcagac agaggtggtc 480 attaccggag ctggtatgag cgccgatcgc acggcgttaa cgcttgacgg tcagagccgt 540 attcaaatgc ttgctaacgg taatgagcaa aaaccgctgg tgctgtctct gcgcgacgcc 600 gagggccagc cagtcacggg catgaaagat cagatcaaga ctgaactaac tttcaaaccg 660 gctggaaata ttgtgactcg ttccctgaag gccactaaat cacaggcaaa gccaacactg 720 ggtgagttca ccgaaactga agcaggggtg tatcagtctg tctttactac cggaacgcag 780 tcaggtgagg caacgattac tgttagcgtt gatggcatga gcaaaaccgt cactgcagaa 840 ctgcgggcca cgatgatgga tgtggcaaac tccaccctga gcgctaacga gccgtcaggt 900 gacgtggttg ctgatggtca gcaagcctat acgttgacgt tgactgcggt ggactccgag 960 ggtaatccgg tgacgggaga agccagccgc ttgcgatttg ttccgcaaga cactaatggt 1020 gtaaccgttg gtgccatttc ggaaataaaa ccaggcgttt acagcgccgc ggtttcttcg 1080 acccgtgccg gaaacgttgt tgtgcgtgct ttcagcgagc agtatcagct gggcacatta 1140 caacaaacgc tgaagtttgt tgccgggccg cttgatgcag cacattcgtc catcaccctg 1200 aatcctgata aaccggtggt tggggggaca gttacggcaa tctggacggt aaaagatgcc 1260 tatgacaacc ctgtgaccag cctcacgccg gaagcgccgt cattagcggg tgccgctgct 1320 gaaggttcta cggcatcggg ctggacaaat aatggtgatg ggacgtggac tgcgcagatt 1380 actctcggct ctacggcggg tgaattagaa gttatgccga agctaaatgg acagaatgcg 1440 gcagcaaatg cggcaaaagt aaccgtggtg gctgatgcgt tatcttcaaa ccagtcgaaa 1500 gtctctgtcg cagaagatca cgtaaaagcc ggcgaaagca caaccgtgac gctggtggcg 1560 aaagatgcgc atggcaacgc tatcagtggt cttgcgttgt cggcaagttt gacggggacc 1620 gcctctgaag gggcgaccgt ttccagttgg accgaaaaag gtaacggttc ctatgttgct 1680 acgttgacta caggtggaaa gacgggcgag cttcgcgtca tgcctctctt caacggccag 1740 ccagcagcca ccgaagccgc gcagttgacg gtcatcgccg gagagatgtc atcagcgaac 1800 tctacgcttg ttgcggacaa taaggctccg accgtcaaaa cgacgacgga actcaccttc 1860 accgtgaagg atgcgtacgg gaacccggtc accgggctga agccagatgc accagtgttt 1920 agcggtgccg ccagcacggg gagtgagcgt ccttcagcag gaaactggac agagaaaggt 1980 aatggggtct acgtgtcgac cttaacgctg ggatctgccg cgggtcagtt gtctgtgatg 2040 ccgcgagtga acggccaaaa tgccgttgct cagccactgg tgctgaacgt tgcaggtgac 2100 gcatctaagg ctgagattcg tgatatgaca gtgaaggtta ataaccaact ggctaatgga 2160 cagtctgcta accagataac cctgaccgtt gtggacacct atggtaaccc gttgcagggg 2220 caggaagtta cgctgacttt accgcagggt gtgaccagca agacggggaa tacagtaaca 2280 actaatgcgg caggtaaagc ggacattgag cttatgtcaa cggttgcggg agaacacaat 2340 atttccgctt cggtgaatgg tgctcagaag acggtcacgg tgaaattcaa cgcggatgcc 2400 agcaccggtc aggcaaacct gcaggtagac gccgctgctc aaaaagtggc aaacggcaaa 2460 gatgccttta cgctgacggc gaacgttgag gataaaaatg gtaaccctgt tccagggagc 2520 ctggtgacct ttaatctgcc ccggggtgtc aagccgctta caggcgataa tgtctgggtg 2580 aaagccaacg atgaggggaa agcagagttg caggtggttt cagtgactgc cggaacgtat 2640 gagatcacgg catcggcagg gaatagccag ccttcgaata cgcagactat aacgtttgta 2700 gccgataagg ctaccgcaac cgtctccggt attgaggtga ttggcaacta tgcactggcg 2760 gacggcaatg ccaaacagac gtataaagtt acggtgactg atgccaataa caacctgttg 2820 aaagatagcg aagtgacgct gactgccagc ccggcaaatt tagttctgac tcccaatggg 2880 acggcgaaaa ctaatgagca aggacaggct attttcaccg ccacgaccac tgtcgcagcg 2940 aaatatacac tcacggcgaa agtgagtcag gccgacggtc aggaatcgac gaaaactgcc 3000 gaatctaaat tcgtcgcgga tgatacaaat gcagtactca ccgcatcatc tgatgtgact 3060 tctctggtgg cggatgggat atcgactgcg aagctggagg tgacactgat gtcggcaaat 3120 aaccccgttg gggggaatat gtgggtcgac attaagacgc cagaaggggt gacggagaag 3180 gattatcagt tcctgccgtc gaaaaatgac catttcgtga gcggaaaaat cacgcgtaca 3240 tttagtacca gcaagcctgg tgtctatacg ttcacattta acgccctgac gtatggcggg 3300 tacgaaatga agccagtgac ggtgaccatt accgcggtgg atgccgatac ggcaaagggc 3360 gaggaggcga tgaactaata ttaagaatat ggaagtaaca ttctaataaa caataatggc 3420 gttgacatct tcaacgccat tatttattga attgcctgac agtagtctcg ttataagttc 3480 atttagatat agcgacagct aaaccggacg aacagggata aatatttcgc aaacaacatc 3540 attgctatcc ttttctacga aatcttcatt gtaataaaac cgctcaatat cactgccgtt 3600 cactctggct aaccccctgg cgggtaattc catcagatag aggtttcgcg cccattcagg 3660 gtagtgctcc cactcacctt catagcggaa agaggcatac agtcctcggt taattgtcca 3720 ctctttcggc atctctgaat cggtttgttt g 3751 <210> 1511 <211> 3594 <212> DNA <213> Escherichia coli O157:H7 <400> 1511 tggcaaaaag tggattagat cataaagaat aaaatgaagc agagtattat gttttaagga 60 attaattaaa agggatttaa acacgctcag aatattcatc gtaattatat ttattttcaa 120 tttatcaggc tgtggatata acgatattca aacctatgat gagcaggtta acgcctcctg 180 gtctgaggta ttgaatcaat atcaacgtcg cgccgatctt attcctaatc ttgtcgccag 240 cattaaaggt tattccagcc atgaacgaga tgtactggaa gccgtaacat tggctcgtag 300 ccaggctaat cgcgccagta gcgatcttca gcaaactccg ggagatgaac aaaaattaca 360 agcctggcaa caggctcaag cgcaggtgac tcgcactctc ggtcagttaa cgataattag 420 tgagcgttac cctgagttaa aatctcagga actctatcaa aatttaatgg tacagcttga 480 aggaagtgaa aatcggattg ccgttgcgcg aggaagatat attaaagcca ttgaacaata 540 taatgtcact atccgcaaat tccccgctgt attaaccgca aaggtcatgg attacacacc 600 aaagaaaaat tatttgccgg atgatgtcgc cgcagtaagt aaagccccaa caatagattt 660 tagccagaat gctaatgctc attaagcggg gaagttctat gcgaaatttt atcttcctta 720 tggctttctt ctgttcatct gtgtttgcca cacaaattcc agtacctgaa tcacccaagt 780 atgtgaatga cttaaccggc acattaacaa acagcgaagt aaacaccctg accaaccaga 840 ttaaagccct gacgcaaaaa aactacgcac agttggtcgt gttagtggtt gaaacaacag 900 gcgatgaaac catcgagcag tacgcgacgc gggtattcga tagctggaaa ccgggtgata 960 aagaccgcga tgatggagtt ctactgttag tcgcctggca ggatcatacc gtgcgtattg 1020 aaatcggtta cggactggaa ggtattatta cggatgcgca gtccgggaaa attattcgca 1080 acagtattat tcctgcattt aaaaaaggcg acctggctgg tggtttgcaa aagggaatca 1140 gcgatattga aagtcgtctg acggggaata atttagcaac gataacaccg accgatcacc 1200 ctttgccctt tagcggttgg tgggcattgt tagtctgggc gatagtactg acgtttattt 1260 ctgccagagg atatatcaaa acgctgggag taatttgctt cgcagctatt gtactggcct 1320 ttgttttacc tatagcaggc ttcagcggaa gctggggagt actcgcaaca tgactctgct 1380 tcgccacacc gttcctggct gtcgccatcg cttttacccc cttcggcaaa aaagttcggg 1440 atttgatgcg tgatgccaac cagccatcac gccatacaag aagcaattct tcctcccact 1500 attcatcatc gtcatcctct tcattcgaca atgacaattt tagcggtggt ggcggttcat 1560 ctggtggcgg tggcgcttcc gggcgctggt aacaaaagga attgatatgc gtatttttct 1620 cttacttctg atgctatgcg gttttcaggt attcgctgaa cgattgcctt cagtgactga 1680 cttaaccggg acattaacga cagaagaaca aactgcttta actcaacaat tacagactct 1740 cgagcagcaa aaccacttcc aggtggccgt gttggttacg ccgaccacag ggggcaaaaa 1800 cattaaactt gcagcctcgc agagatacgg ggtatatcac tggaaacccg ttggagagaa 1860 gcgatatggc gaaggtatct taattctcgt cgtatggccg gaagggctgg cgtcaatgaa 1920 gattggacat ggactggaag agatgttgcc gccggaacaa gctgcgcaaa ttgttcgtta 1980 ccatatgcag ccagaattcg aaaaaaacaa tctctttgct ggattaacgg gcggaattga 2040 aagcatcgca cagtttaccc atatcaaagc gaaccttagc cctttggatg ctttagccaa 2100 tcatctgttt gctaatccgc aacgttcgct gccatgtctt gcctggacac tgctgatgat 2160 cgttgccatc gttgtcctct ggctatttgc cagccgccca cggcgtggca tatggatgat 2220 atcgatgatt acccctatgg tctggttttt ctcctttcag gacgatgtca tcattcggcg 2280 ggtatcggtc gtttgtttta gtttattgtt agcaacaacc tgcaagcagc gtctcgcggt 2340 agtttttaat atgtgccgcg tatttcctat gatgctgacc ccaaaaaata aaaacgctaa 2400 agtgaaaaaa caaaagaaga ctccgcaggt tcgtgaatca ggacgaaatt cattgtttgt 2460 cgtgatgctg ataattattg tgggatggtg cctggtgttc gccagtaata aagatattgc 2520 attcatctca acaattattg ggttaattga tcattttatc ggcccaataa ccattgctgg 2580 catcgttctg ctgatcattg tggccaaatt tactggcaat cttaagctgg ggtcaggaga 2640 aaaaagcaac aggaaaacgg ggaatcgtaa tgctcattct cgctcttcgt cgagaaattc 2700 tttccgcggt ggtggcggtt cttcaggagg cggcggttca tccgtccgtt ggtgatcgta 2760 atgcgcttaa tctttattct attcactttg tggtgccttc ctgggcttgc ccagcaaatt 2820 gctgtgccgg aactgcgcca acaggtgacc gatattactg gtacgttaag cacttctgaa 2880 caacaatcac tgacacagca actgcaggat attacacata aaacacgggc gcaggtcgct 2940 gtattagtag tgccgtccac cggagacgat tccattgaac aatatgctac aagggttttt 3000 gatagctgga aactgggaga taagcagaga aacgatggta ttttacttct ggttgcctgg 3060 gaggatcatg ctgttcgtat tgaggttggc tacgggctgg aaggggtggt taccgacctg 3120 caagcggcga agattatcag ggatatattg atccctgcct tcaaaagtga tgacctgatg 3180 ggtggattaa cactggcaag cgaaaatatc ggcgcgcttc tgttgaatgg tgaattaccg 3240 gaagacaggg gggattatta cagtatcaat ccccctattc cattatcgct tgctgtaatt 3300 atattgctgg cggtactttc atattttatt gtttttaccg atccgtcgaa tttaccctgg 3360 atcactctca ctggcgccat ttacgggatg gtattcctct atgttgccga gccaggacca 3420 tggaccaatt taatcgttgc ctgcggtatg ttaacgcctt ttgcgatcgt accactggtt 3480 attttttggc ttatcgtcaa taaaaagcta cgcgccaaat acaaaaaact cagtaaagat 3540 agagcttcaa gaaaaggttc ttcttcatcc tcttccggtg gcggctcaag tggc 3594 <210> 1512 <211> 132 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(290..685) <400> 1512 Leu Ala Arg Ser Gln Ala Asn Arg Ala Ser Ser Asp Leu Gln Gln Thr 1 5 10 15 Pro Gly Asp Glu Gln Lys Leu Gln Ala Trp Gln Gln Ala Gln Ala Gln 20 25 30 Val Thr Arg Thr Leu Gly Gln Leu Thr Ile Ile Ser Glu Arg Tyr Pro 35 40 45 Glu Leu Lys Ser Gln Glu Leu Tyr Gln Asn Leu Met Val Gln Leu Glu 50 55 60 Gly Ser Glu Asn Arg Ile Ala Val Ala Arg Gly Arg Tyr Ile Lys Ala 65 70 75 80 Ile Glu Gln Tyr Asn Val Thr Ile Arg Lys Phe Pro Ala Val Leu Thr 85 90 95 Ala Lys Val Met Asp Tyr Thr Pro Lys Lys Asn Tyr Leu Pro Asp Asp 100 105 110 Val Ala Ala Val Ser Lys Ala Pro Thr Ile Asp Phe Ser Gln Asn Ala 115 120 125 Asn Ala His * 130 <210> 1513 <211> 225 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(699..1373) <400> 1513 Met Arg Asn Phe Ile Phe Leu Met Ala Phe Phe Cys Ser Ser Val Phe 1 5 10 15 Ala Thr Gln Ile Pro Val Pro Glu Ser Pro Lys Tyr Val Asn Asp Leu 20 25 30 Thr Gly Thr Leu Thr Asn Ser Glu Val Asn Thr Leu Thr Asn Gln Ile 35 40 45 Lys Ala Leu Thr Gln Lys Asn Tyr Ala Gln Leu Val Val Leu Val Val 50 55 60 Glu Thr Thr Gly Asp Glu Thr Ile Glu Gln Tyr Ala Thr Arg Val Phe 65 70 75 80 Asp Ser Trp Lys Pro Gly Asp Lys Asp Arg Asp Asp Gly Val Leu Leu 85 90 95 Leu Val Ala Trp Gln Asp His Thr Val Arg Ile Glu Ile Gly Tyr Gly 100 105 110 Leu Glu Gly Ile Ile Thr Asp Ala Gln Ser Gly Lys Ile Ile Arg Asn 115 120 125 Ser Ile Ile Pro Ala Phe Lys Lys Gly Asp Leu Ala Gly Gly Leu Gln 130 135 140 Lys Gly Ile Ser Asp Ile Glu Ser Arg Leu Thr Gly Asn Asn Leu Ala 145 150 155 160 Thr Ile Thr Pro Thr Asp His Pro Leu Pro Phe Ser Gly Trp Trp Ala 165 170 175 Leu Leu Val Trp Ala Ile Val Leu Thr Phe Ile Ser Ala Arg Gly Tyr 180 185 190 Ile Lys Thr Leu Gly Val Ile Cys Phe Ala Ala Ile Val Leu Ala Phe 195 200 205 Val Leu Pro Ile Ala Gly Phe Ser Gly Ser Trp Gly Val Leu Ala Thr 210 215 220 * <210> 1514 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1453..1605) <400> 1514 Met Pro Thr Ser His His Ala Ile Gln Glu Ala Ile Leu Pro Pro Thr 1 5 10 15 Ile His His Arg His Pro Leu His Ser Thr Met Thr Ile Leu Ala Val 20 25 30 Val Ala Val His Leu Val Ala Val Ala Leu Pro Gly Ala Gly Asn Lys 35 40 45 Arg Asn * 50 <210> 1515 <211> 383 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1607..2755) <400> 1515 Met Arg Ile Phe Leu Leu Leu Leu Met Leu Cys Gly Phe Gln Val Phe 1 5 10 15 Ala Glu Arg Leu Pro Ser Val Thr Asp Leu Thr Gly Thr Leu Thr Thr 20 25 30 Glu Glu Gln Thr Ala Leu Thr Gln Gln Leu Gln Thr Leu Glu Gln Gln 35 40 45 Asn His Phe Gln Val Ala Val Leu Val Thr Pro Thr Thr Gly Gly Lys 50 55 60 Asn Ile Lys Leu Ala Ala Ser Gln Arg Tyr Gly Val Tyr His Trp Lys 65 70 75 80 Pro Val Gly Glu Lys Arg Tyr Gly Glu Gly Ile Leu Ile Leu Val Val 85 90 95 Trp Pro Glu Gly Leu Ala Ser Met Lys Ile Gly His Gly Leu Glu Glu 100 105 110 Met Leu Pro Pro Glu Gln Ala Ala Gln Ile Val Arg Tyr His Met Gln 115 120 125 Pro Glu Phe Glu Lys Asn Asn Leu Phe Ala Gly Leu Thr Gly Gly Ile 130 135 140 Glu Ser Ile Ala Gln Phe Thr His Ile Lys Ala Asn Leu Ser Pro Leu 145 150 155 160 Asp Ala Leu Ala Asn His Leu Phe Ala Asn Pro Gln Arg Ser Leu Pro 165 170 175 Cys Leu Ala Trp Thr Leu Leu Met Ile Val Ala Ile Val Val Leu Trp 180 185 190 Leu Phe Ala Ser Arg Pro Arg Arg Gly Ile Trp Met Ile Ser Met Ile 195 200 205 Thr Pro Met Val Trp Phe Phe Ser Phe Gln Asp Asp Val Ile Ile Arg 210 215 220 Arg Val Ser Val Val Cys Phe Ser Leu Leu Leu Ala Thr Thr Cys Lys 225 230 235 240 Gln Arg Leu Ala Val Val Phe Asn Met Cys Arg Val Phe Pro Met Met 245 250 255 Leu Thr Pro Lys Asn Lys Asn Ala Lys Val Lys Lys Gln Lys Lys Thr 260 265 270 Pro Gln Val Arg Glu Ser Gly Arg Asn Ser Leu Phe Val Val Met Leu 275 280 285 Ile Ile Ile Val Gly Trp Cys Leu Val Phe Ala Ser Asn Lys Asp Ile 290 295 300 Ala Phe Ile Ser Thr Ile Ile Gly Leu Ile Asp His Phe Ile Gly Pro 305 310 315 320 Ile Thr Ile Ala Gly Ile Val Leu Leu Ile Ile Val Ala Lys Phe Thr 325 330 335 Gly Asn Leu Lys Leu Gly Ser Gly Glu Lys Ser Asn Arg Lys Thr Gly 340 345 350 Asn Arg Asn Ala His Ser Arg Ser Ser Ser Arg Asn Ser Phe Arg Gly 355 360 365 Gly Gly Gly Ser Ser Gly Gly Gly Gly Ser Ser Val Arg Trp * 370 375 380 <210> 1516 <211> 3518 <212> DNA <213> Escherichia coli O157:H7 <400> 1516 aaaaatgtaa atacatcatt caaatcaata tcacctcggc atacatccat ccaaaataat 60 aatcgtgatc gatcgattaa taataaccga tcgatcacgg ttatatattg ctctattttt 120 gcaaatcaaa tcacaaataa tcaaataaga tctttaattg aactgttttg attactacag 180 tgcacttacc gaatacatac agaggcattg cttagcgaaa cacaaaattt cctgagacat 240 tattaacgtc agcagaaggt tcatgcattg acaacggaaa tgtacgcgta tggagggcgt 300 tccgacgatg tttgccaaat tcatagatgt tattcaaacg tttttaactg aaccggcaat 360 tttaattggt ttgctggtgg gtattggtta tgcccttgat aagaaatcgc caataaaaat 420 tattaccggc atggtcagcg ccatggtggg attaatgatg gtgttatttg gtggtttcca 480 gttttccgca acatttaaac cggtagcaga agccgtaagt aaagcctatg gtgttcacgg 540 atatttaatg gattcctacg caatgaaagc ggcaacgcaa attgcattgg gggataattt 600 tggttatgtc gggtatgtat ttgtactggc gttttttacc aacctgctgc tggtattatt 660 tggtcggtat actggtgcca aagggatatt tttgacaggg aataccggtg tttcacattc 720 tcaggcggta ttatggttga ttgtcttttg gctgggtttt agctggacta catccattat 780 tattgccgga atattaacgg gtgtattctg ggcgttctcc accacgctca ttgttaagcc 840 cattgccaaa gttaccaaag atgccggttt taccattgct cataaccaga tgttgggatt 900 gtggtttttc tccaaattcg cccataaatt tggtgaccct gaaaagcacg atgctgaaaa 960 cctgaaactt cccgggtggc tggcgatttt taaccataac gtaacggcta tcgccattgt 1020 gatgacgctg tttgtcggtg gtttcttgct atcaacgggt atcgataatg tccagttaat 1080 ggcgaaaggc aagccctggt acatctatat catcaacctt ggcttacagt tctccatgta 1140 tatggtcatt ctgctgcagg gtgtgcgcat gatggtgggc gaaattaacg gttcgtttaa 1200 aggctggcaa gatcgcttta ttcctaacgc tattcctgct gtcgatgttg cagcgctgtt 1260 acctttttca cccaatgccg caacgttagg cttcgtcttc tgtacttttg gcaccatttt 1320 ttcgatgggg atcttattac tggttcacag cccaattatg gtattgcctg gctttgtacc 1380 tctgtttttc tctggcggtc caattggcgt attagcaaac cgcatgggcg gataccgttc 1440 cgtaattatc tgtacgttct tgctgggtat tattcagacc ttcggtacgg tgtgggctat 1500 tccgttaacc gggcttgctg aaaatggcgt cggctggaca ggaatatttg actgggcaac 1560 cgtatggcct gctatttgtg aagttctgaa atttatcgct gcaacattcc atcttggtcc 1620 ttacgcgggt taattaaata ttaagggttt aaaaatgaaa gatacaatta atattctgtt 1680 tgtctgtggt tacggtgtag gcagtagcgt tatgttacaa acggtcgtta aaaaagcgct 1740 gaccaaatat gatttcaaag ttgaaatgga acataccgcc gcaggtgaag tcggcggatt 1800 taccgactgg gcggatattt ttgctatttc caaaaaatta ctcgatgtgg ttagtcttga 1860 cccgaaacaa gggcaatatt tgattccgat agagaatatt atggacggtg aaactattgg 1920 tcagcaaatt tatgaagtgg ttcagcaaca ttttccgcat ttaattaatc aataaggtag 1980 ggcgtaatga gagcgattat tctgctgttc gatagtctga ataaacgtta tctgccacct 2040 tatggcgatg cgttaaccaa agcgcctaat ttccaacgtc tggcggctca tgccgccacc 2100 tttgaaaaca gttacgtcgg cagtatgccg tgtatgcctg cccggcggga gttgcatacc 2160 gggcgatgta acttcctgca tcgggagtgg gggccgttag aaccgtttga cgattccatg 2220 ccggagctgc ttaaaaaggc ggggatctat acccacctga taagcgatca tttgcattac 2280 tgggaagatg gcggcgagaa ttatcataat cgctacagtt cgtgggagat tgtgcgcgga 2340 caggaaggcg atcactggca tgcaagcgtt gcgcaaccgc ctattcccga ggtgctacgg 2400 gtgccgcaaa agcagaccgg tggcggtgtt tctggtctgt ggcgccatga ctgggcaaac 2460 cgggaatata ttcagcagga agcggatttt ccacaaacta aagtgtttga tgcaggctgt 2520 gcctttatcc acaaaaatca cgcggaagat aactggttat tgcagatcga aacgtttgat 2580 ccgcacgagc cgtttcacac aacggaagag tatctttcct tgtatgaaga taactgggat 2640 ggaccgcatt atgactggcc gcgtggccgg gtgcaggaaa gcgacgaggc cgtggagcac 2700 atccgttgcc ggtatcgttc gctggtgtcg atgtgcgatc gcaacctggg gcgcattctc 2760 gacctgatgg atgagcacga tctgtggcga gataccatgc tgattgtcgg cactgaccac 2820 ggctttttac tcggtgagca tggctggtgg gcgaaaaacc agatgcctta ttacaacgaa 2880 gttgccaata atccgttgtt tatctggaac ccgcgcagtg gtgtaaaagg agagcggcga 2940 caggcactgg tacaaatgat cgactgggcg ccaacgttgt atgacttttt tcaacagcca 3000 gtgccgcccg atgtgcaggg gcaaccgctg gcgaaaacgg tcagtcacga tgaaccagta 3060 cgcagctcgg cgatgtttgg tgttttcagt ggtcatgcta acgtaactga tgggcgttat 3120 gtgtatatgc gtgcagcgct gccggggcgt gaggatgata ttgccaacta cacgttgatg 3180 tcctgcaaaa tgaacagccg ctatccggtg gatgagatgc gggctttatc gctggcccca 3240 ccgtttcgtt ttaccaaagg gttacaggta ttacgcatcc cggcacagga aaaatataag 3300 gggttgaatc agtttggtca tttgctgttt gatctgcaaa acgatccgca gcagctacat 3360 ccgattcatg atgatgtgat cgagtcccgg atgatcgcgt tgctgattca gttgatgaaa 3420 gataatgatg cgccgccaga gcagtttcag cgcctgggat tagcgtagag aagtgatttt 3480 gccggagtgg gtgttcgccc actccggcaa atgaataa 3518 <210> 1517 <211> 448 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(290..1633) <400> 1517 Met Glu Gly Val Pro Thr Met Phe Ala Lys Phe Ile Asp Val Ile Gln 1 5 10 15 Thr Phe Leu Thr Glu Pro Ala Ile Leu Ile Gly Leu Leu Val Gly Ile 20 25 30 Gly Tyr Ala Leu Asp Lys Lys Ser Pro Ile Lys Ile Ile Thr Gly Met 35 40 45 Val Ser Ala Met Val Gly Leu Met Met Val Leu Phe Gly Gly Phe Gln 50 55 60 Phe Ser Ala Thr Phe Lys Pro Val Ala Glu Ala Val Ser Lys Ala Tyr 65 70 75 80 Gly Val His Gly Tyr Leu Met Asp Ser Tyr Ala Met Lys Ala Ala Thr 85 90 95 Gln Ile Ala Leu Gly Asp Asn Phe Gly Tyr Val Gly Tyr Val Phe Val 100 105 110 Leu Ala Phe Phe Thr Asn Leu Leu Leu Val Leu Phe Gly Arg Tyr Thr 115 120 125 Gly Ala Lys Gly Ile Phe Leu Thr Gly Asn Thr Gly Val Ser His Ser 130 135 140 Gln Ala Val Leu Trp Leu Ile Val Phe Trp Leu Gly Phe Ser Trp Thr 145 150 155 160 Thr Ser Ile Ile Ile Ala Gly Ile Leu Thr Gly Val Phe Trp Ala Phe 165 170 175 Ser Thr Thr Leu Ile Val Lys Pro Ile Ala Lys Val Thr Lys Asp Ala 180 185 190 Gly Phe Thr Ile Ala His Asn Gln Met Leu Gly Leu Trp Phe Phe Ser 195 200 205 Lys Phe Ala His Lys Phe Gly Asp Pro Glu Lys His Asp Ala Glu Asn 210 215 220 Leu Lys Leu Pro Gly Trp Leu Ala Ile Phe Asn His Asn Val Thr Ala 225 230 235 240 Ile Ala Ile Val Met Thr Leu Phe Val Gly Gly Phe Leu Leu Ser Thr 245 250 255 Gly Ile Asp Asn Val Gln Leu Met Ala Lys Gly Lys Pro Trp Tyr Ile 260 265 270 Tyr Ile Ile Asn Leu Gly Leu Gln Phe Ser Met Tyr Met Val Ile Leu 275 280 285 Leu Gln Gly Val Arg Met Met Val Gly Glu Ile Asn Gly Ser Phe Lys 290 295 300 Gly Trp Gln Asp Arg Phe Ile Pro Asn Ala Ile Pro Ala Val Asp Val 305 310 315 320 Ala Ala Leu Leu Pro Phe Ser Pro Asn Ala Ala Thr Leu Gly Phe Val 325 330 335 Phe Cys Thr Phe Gly Thr Ile Phe Ser Met Gly Ile Leu Leu Leu Val 340 345 350 His Ser Pro Ile Met Val Leu Pro Gly Phe Val Pro Leu Phe Phe Ser 355 360 365 Gly Gly Pro Ile Gly Val Leu Ala Asn Arg Met Gly Gly Tyr Arg Ser 370 375 380 Val Ile Ile Cys Thr Phe Leu Leu Gly Ile Ile Gln Thr Phe Gly Thr 385 390 395 400 Val Trp Ala Ile Pro Leu Thr Gly Leu Ala Glu Asn Gly Val Gly Trp 405 410 415 Thr Gly Ile Phe Asp Trp Ala Thr Val Trp Pro Ala Ile Cys Glu Val 420 425 430 Leu Lys Phe Ile Ala Ala Thr Phe His Leu Gly Pro Tyr Ala Gly * 435 440 445 <210> 1518 <211> 107 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1655..1975) <400> 1518 Met Lys Asp Thr Ile Asn Ile Leu Phe Val Cys Gly Tyr Gly Val Gly 1 5 10 15 Ser Ser Val Met Leu Gln Thr Val Val Lys Lys Ala Leu Thr Lys Tyr 20 25 30 Asp Phe Lys Val Glu Met Glu His Thr Ala Ala Gly Glu Val Gly Gly 35 40 45 Phe Thr Asp Trp Ala Asp Ile Phe Ala Ile Ser Lys Lys Leu Leu Asp 50 55 60 Val Val Ser Leu Asp Pro Lys Gln Gly Gln Tyr Leu Ile Pro Ile Glu 65 70 75 80 Asn Ile Met Asp Gly Glu Thr Ile Gly Gln Gln Ile Tyr Glu Val Val 85 90 95 Gln Gln His Phe Pro His Leu Ile Asn Gln * 100 105 <210> 1519 <211> 494 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1987..3468) <400> 1519 Met Arg Ala Ile Ile Leu Leu Phe Asp Ser Leu Asn Lys Arg Tyr Leu 1 5 10 15 Pro Pro Tyr Gly Asp Ala Leu Thr Lys Ala Pro Asn Phe Gln Arg Leu 20 25 30 Ala Ala His Ala Ala Thr Phe Glu Asn Ser Tyr Val Gly Ser Met Pro 35 40 45 Cys Met Pro Ala Arg Arg Glu Leu His Thr Gly Arg Cys Asn Phe Leu 50 55 60 His Arg Glu Trp Gly Pro Leu Glu Pro Phe Asp Asp Ser Met Pro Glu 65 70 75 80 Leu Leu Lys Lys Ala Gly Ile Tyr Thr His Leu Ile Ser Asp His Leu 85 90 95 His Tyr Trp Glu Asp Gly Gly Glu Asn Tyr His Asn Arg Tyr Ser Ser 100 105 110 Trp Glu Ile Val Arg Gly Gln Glu Gly Asp His Trp His Ala Ser Val 115 120 125 Ala Gln Pro Pro Ile Pro Glu Val Leu Arg Val Pro Gln Lys Gln Thr 130 135 140 Gly Gly Gly Val Ser Gly Leu Trp Arg His Asp Trp Ala Asn Arg Glu 145 150 155 160 Tyr Ile Gln Gln Glu Ala Asp Phe Pro Gln Thr Lys Val Phe Asp Ala 165 170 175 Gly Cys Ala Phe Ile His Lys Asn His Ala Glu Asp Asn Trp Leu Leu 180 185 190 Gln Ile Glu Thr Phe Asp Pro His Glu Pro Phe His Thr Thr Glu Glu 195 200 205 Tyr Leu Ser Leu Tyr Glu Asp Asn Trp Asp Gly Pro His Tyr Asp Trp 210 215 220 Pro Arg Gly Arg Val Gln Glu Ser Asp Glu Ala Val Glu His Ile Arg 225 230 235 240 Cys Arg Tyr Arg Ser Leu Val Ser Met Cys Asp Arg Asn Leu Gly Arg 245 250 255 Ile Leu Asp Leu Met Asp Glu His Asp Leu Trp Arg Asp Thr Met Leu 260 265 270 Ile Val Gly Thr Asp His Gly Phe Leu Leu Gly Glu His Gly Trp Trp 275 280 285 Ala Lys Asn Gln Met Pro Tyr Tyr Asn Glu Val Ala Asn Asn Pro Leu 290 295 300 Phe Ile Trp Asn Pro Arg Ser Gly Val Lys Gly Glu Arg Arg Gln Ala 305 310 315 320 Leu Val Gln Met Ile Asp Trp Ala Pro Thr Leu Tyr Asp Phe Phe Gln 325 330 335 Gln Pro Val Pro Pro Asp Val Gln Gly Gln Pro Leu Ala Lys Thr Val 340 345 350 Ser His Asp Glu Pro Val Arg Ser Ser Ala Met Phe Gly Val Phe Ser 355 360 365 Gly His Ala Asn Val Thr Asp Gly Arg Tyr Val Tyr Met Arg Ala Ala 370 375 380 Leu Pro Gly Arg Glu Asp Asp Ile Ala Asn Tyr Thr Leu Met Ser Cys 385 390 395 400 Lys Met Asn Ser Arg Tyr Pro Val Asp Glu Met Arg Ala Leu Ser Leu 405 410 415 Ala Pro Pro Phe Arg Phe Thr Lys Gly Leu Gln Val Leu Arg Ile Pro 420 425 430 Ala Gln Glu Lys Tyr Lys Gly Leu Asn Gln Phe Gly His Leu Leu Phe 435 440 445 Asp Leu Gln Asn Asp Pro Gln Gln Leu His Pro Ile His Asp Asp Val 450 455 460 Ile Glu Ser Arg Met Ile Ala Leu Leu Ile Gln Leu Met Lys Asp Asn 465 470 475 480 Asp Ala Pro Pro Glu Gln Phe Gln Arg Leu Gly Leu Ala * 485 490 <210> 1520 <211> 3511 <212> DNA <213> Escherichia coli O157:H7 <400> 1520 ggttcaaaca ggtgctgcac acaaccagac gcggcacctg ttttattacc tgaactgata 60 atgaccttcg cccaatcgga taacccttcc ctcttcttct gcgcggttca gccacacact 120 aatttgttcg atggttaaac cagtacaaga cgccagcctt tcaatactta tcgattcctt 180 tgcaaggatc gccagttccg ccacaaagag ttgataaaaa tcgacaggcg tatacgcggg 240 cattactgcg taatttgcgt catcttcatg cagcgaaaac agttctggtt gagcgttacg 300 gagtgctctg tcatacatca gcccaggaac gtctggcagt ctgatcgtca cattctcagc 360 ctgttcagca ctccatgacg ccccattttc tactaatcgt gaattggctg attgcatatc 420 ctgatttggt ttaacctgca caggcagcca ctgatgtttt aatgcctcca tcgccccggt 480 tatcgttcca ccggtcattc ccgcacgtac aaccattgcg ctttcagcaa ggcaataaat 540 atatttattt cgcgccatcg cattgccgac ggtgaaacgt acctctgggt aaaacggcga 600 aatcaacacc aggttgcctg ctataagccc ttcacgccat ttcactaacg tactcgtttt 660 taacaagcta tcagctaata cgccaacggc agttcccccg gcctccagtg ccgacgccat 720 tgcacattca tcaatacctc gcgcaccacc agagataacg caaatcccct gttgggccag 780 tttcgcggcc agttgttggg tatagcgcaa atcgtcagtc ggagcatctc gcgagccaac 840 aatcgccata ccttccgctt gcagtaatgc tttattcccg cagccaaata aaacgggagg 900 tgcatccgtt cgcaatcggt ttttcaagcg aacgggataa tcagcatctc cgcgggttaa 960 gatccataaa ccggcgcgtt gccacttatc taccgccaac gccagactat gaccacgcgc 1020 cagcaagcca agaatacgct cctgagaaat acgcggatcg ctccagcctg taagtttctc 1080 ttgcggttgc ggcaccagaa gctcggcggg actgatacgt tggtgcttca gccataatgc 1140 aaacttcccc cattcactat tactaagagg tttatactta ctcgccgccg cgcgagaaaa 1200 atcgctggtt agcaggagag ttgcttgtgc attggctgaa agattcatca attttttacc 1260 gaggtagaag caagggcaag aggataaacc gtcgggcaac ctgcctggcg taacagtgct 1320 gttagaactg tcagcgtcca tgcagaatcc acgatatcgt caaccagcaa cgccggacca 1380 ggcatcaaag gaggggtaat cacaaacgcc ccgtcgagat tttgacactg gtggaaacgg 1440 ttttgctgca ttttctgcgg tggattgtcc acgacttttt caatggcatc aataaaaggt 1500 aagccaagtt tcgccgccag tcgccgggca aaatcaggaa ccaggtcgag gtgctttcaa 1560 aatcaggaac caggtcgagg tgctttaatg aaggaacgca gcatacccag gttggttcag 1620 gatgcggatt ccagcgttgg cgaaccattt ccgcacatgc ctccaccagt tcatcactga 1680 atcgccccgt ttttttctcc tgtgctacct gctttcccca cccggaatat ccccaacgag 1740 aaaggattcg ccccgtagat ccttgtaaac tcgcaggcaa gttcccttta aatccgtatt 1800 gcgtaaaagc cccagctgcc acctgtttat tgagatttaa tgacaggtca gcgtgtttaa 1860 taaataagtt tgccgcatgg agtaagccgc tatcaatgtc gggcgacaac aacggatgct 1920 gaagacaact gctacattta ccacaatgtt cggcacctgg ctcatcgagt gcgcggcgca 1980 gaaattgcat tttgcactcc ttggtcgtga tatagctttc aacgtctgcc agctcacttt 2040 ttctctgatt catcaaatgg ttaattcgtt catggtcagg agaaaaactg acaattgttc 2100 tgcgccataa tttctcggta tacaccacag gcgatggatt ttcagctacc aataatttca 2160 gtgctttttc tatttgccca taacggagat tcgtccgttg ttcaatgcct cgtaaggtaa 2220 gaccgtcatt cacgctaagt acgttgagta tttcatgaat ttgcgcctcc gcaggaaagg 2280 cgctttcacg gaagaattta tgaatagcac ggtcttcact gccgcaaagc agtatgccaa 2340 cagcagaatc gataccgcga ccggcacgcc ccacctgtta gtagtaacca actatcgaac 2400 ctggcatctg gtaatgaata acaaacccca aatccggttt gtcaaagccc attcccagcg 2460 ccgttgtcgc aaccagcact ttaattttat ttgccagcaa cgcctgctcc agatattccc 2520 tggcagtatt agaatcttcc gcgccttcac aagtcacgcc gctgtagtaa gcaaatgcac 2580 tgataccatt tttccttaac cactcggcga caagttcggc atcgcgagta gtcagggtat 2640 aaacaattcc cgatttggaa aactgaggga taaccgttgc taaccatgcc agacgggatg 2700 agtgttcacc taagactaag gcatcaagcg ccaaactttc gcgagccagc gttccacgct 2760 gaatcacaat gtcacccaat tgctgacgga tatcctcaac gacacggtta ttcgctgtcg 2820 cggttgtacc cagaacaggg gtattcgcag gtagttgcgc aaaatatcta atatacgtcg 2880 gtaatccggg cgaaaatcgt ggccccaatc agagatgcag tgcgcctcgt cgaccacaag 2940 caagccaata tgatcggcta taggatataa aaccgtttcg ataaagtcct ggtttgccaa 3000 acgttccggg gaaaccagca agcaatcgac ctcaccttgc agcaacttat cgctaatgcg 3060 ctgccattct tctctgtttg tagaattcaa cgtttcagcc gtaataccta accgttcagc 3120 ggcggcaacc tggttacgca tcagggcaag caaaggagag atgataattg tcgggccagc 3180 gccgcgatcg cggaagattt tactggcgat gaagtacaca gcacttttcc cccagccagt 3240 gcgttggaca accagcagtt ttcgccgttg gttcaccacc gcgtctatgg cttcccattg 3300 cccttccctg aaagtagcgg tggtatttcc taacatccgc tgtaaaagca attcagctgc 3360 gtgcttttcc atctttatct cctgcgatct ttaggcagtg attagaacgg attatttgca 3420 ggtaaatttg cgagagagat caaaaagatg aagagaggag aaaagagaaa tgaattactg 3480 cgagcaagct cgcagtaatt tgtcgcagta a 3511 <210> 1521 <211> 401 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(46..1248) <400> 1521 Met Asn Leu Ser Ala Asn Ala Gln Ala Thr Leu Leu Leu Thr Ser Asp 1 5 10 15 Phe Ser Arg Ala Ala Ala Ser Lys Tyr Lys Pro Leu Ser Asn Ser Glu 20 25 30 Trp Gly Lys Phe Ala Leu Trp Leu Lys His Gln Arg Ile Ser Pro Ala 35 40 45 Glu Leu Leu Val Pro Gln Pro Gln Glu Lys Leu Thr Gly Trp Ser Asp 50 55 60 Pro Arg Ile Ser Gln Glu Arg Ile Leu Gly Leu Leu Ala Arg Gly His 65 70 75 80 Ser Leu Ala Leu Ala Val Asp Lys Trp Gln Arg Ala Gly Leu Trp Ile 85 90 95 Leu Thr Arg Gly Asp Ala Asp Tyr Pro Val Arg Leu Lys Asn Arg Leu 100 105 110 Arg Thr Asp Ala Pro Pro Val Leu Phe Gly Cys Gly Asn Lys Ala Leu 115 120 125 Leu Gln Ala Glu Gly Met Ala Ile Val Gly Ser Arg Asp Ala Pro Thr 130 135 140 Asp Asp Leu Arg Tyr Thr Gln Gln Leu Ala Ala Lys Leu Ala Gln Gln 145 150 155 160 Gly Ile Cys Val Ile Ser Gly Gly Ala Arg Gly Ile Asp Glu Cys Ala 165 170 175 Met Ala Ser Ala Leu Glu Ala Gly Gly Thr Ala Val Gly Val Leu Ala 180 185 190 Asp Ser Leu Leu Lys Thr Ser Thr Leu Val Lys Trp Arg Glu Gly Leu 195 200 205 Ile Ala Gly Asn Leu Val Leu Ile Ser Pro Phe Tyr Pro Glu Val Arg 210 215 220 Phe Thr Val Gly Asn Ala Met Ala Arg Asn Lys Tyr Ile Tyr Cys Leu 225 230 235 240 Ala Glu Ser Ala Met Val Val Arg Ala Gly Met Thr Gly Gly Thr Ile 245 250 255 Thr Gly Ala Met Glu Ala Leu Lys His Gln Trp Leu Pro Val Gln Val 260 265 270 Lys Pro Asn Gln Asp Met Gln Ser Ala Asn Ser Arg Leu Val Glu Asn 275 280 285 Gly Ala Ser Trp Ser Ala Glu Gln Ala Glu Asn Val Thr Ile Arg Leu 290 295 300 Pro Asp Val Pro Gly Leu Met Tyr Asp Arg Ala Leu Arg Asn Ala Gln 305 310 315 320 Pro Glu Leu Phe Ser Leu His Glu Asp Asp Ala Asn Tyr Ala Val Met 325 330 335 Pro Ala Tyr Thr Pro Val Asp Phe Tyr Gln Leu Phe Val Ala Glu Leu 340 345 350 Ala Ile Leu Ala Lys Glu Ser Ile Ser Ile Glu Arg Leu Ala Ser Cys 355 360 365 Thr Gly Leu Thr Ile Glu Gln Ile Ser Val Trp Leu Asn Arg Ala Glu 370 375 380 Glu Glu Gly Arg Val Ile Arg Leu Gly Glu Gly His Tyr Gln Phe Arg 385 390 395 400 * <210> 1522 <211> 52 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1248..1403) <400> 1522 Val Ile Thr Pro Pro Leu Met Pro Gly Pro Ala Leu Leu Val Asp Asp 1 5 10 15 Ile Val Asp Ser Ala Trp Thr Leu Thr Val Leu Thr Ala Leu Leu Arg 20 25 30 Gln Ala Gly Cys Pro Thr Val Tyr Pro Leu Ala Leu Ala Ser Thr Ser 35 40 45 Val Lys Asn * 50 <210> 1523 <211> 325 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1400..2374) <400> 1523 Val Gly Arg Ala Gly Arg Gly Ile Asp Ser Ala Val Gly Ile Leu Leu 1 5 10 15 Cys Gly Ser Glu Asp Arg Ala Ile His Lys Phe Phe Arg Glu Ser Ala 20 25 30 Phe Pro Ala Glu Ala Gln Ile His Glu Ile Leu Asn Val Leu Ser Val 35 40 45 Asn Asp Gly Leu Thr Leu Arg Gly Ile Glu Gln Arg Thr Asn Leu Arg 50 55 60 Tyr Gly Gln Ile Glu Lys Ala Leu Lys Leu Leu Val Ala Glu Asn Pro 65 70 75 80 Ser Pro Val Val Tyr Thr Glu Lys Leu Trp Arg Arg Thr Ile Val Ser 85 90 95 Phe Ser Pro Asp His Glu Arg Ile Asn His Leu Met Asn Gln Arg Lys 100 105 110 Ser Glu Leu Ala Asp Val Glu Ser Tyr Ile Thr Thr Lys Glu Cys Lys 115 120 125 Met Gln Phe Leu Arg Arg Ala Leu Asp Glu Pro Gly Ala Glu His Cys 130 135 140 Gly Lys Cys Ser Ser Cys Leu Gln His Pro Leu Leu Ser Pro Asp Ile 145 150 155 160 Asp Ser Gly Leu Leu His Ala Ala Asn Leu Phe Ile Lys His Ala Asp 165 170 175 Leu Ser Leu Asn Leu Asn Lys Gln Val Ala Ala Gly Ala Phe Thr Gln 180 185 190 Tyr Gly Phe Lys Gly Asn Leu Pro Ala Ser Leu Gln Gly Ser Thr Gly 195 200 205 Arg Ile Leu Ser Arg Trp Gly Tyr Ser Gly Trp Gly Lys Gln Val Ala 210 215 220 Gln Glu Lys Lys Thr Gly Arg Phe Ser Asp Glu Leu Val Glu Ala Cys 225 230 235 240 Ala Glu Met Val Arg Gln Arg Trp Asn Pro His Pro Glu Pro Thr Trp 245 250 255 Val Cys Cys Val Pro Ser Leu Lys His Leu Asp Leu Val Pro Asp Phe 260 265 270 Glu Ser Thr Ser Thr Trp Phe Leu Ile Leu Pro Gly Asp Trp Arg Arg 275 280 285 Asn Leu Ala Tyr Leu Leu Leu Met Pro Leu Lys Lys Ser Trp Thr Ile 290 295 300 His Arg Arg Lys Cys Ser Lys Thr Val Ser Thr Ser Val Lys Ile Ser 305 310 315 320 Thr Gly Arg Leu * <210> 1524 <211> 177 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2378..2908) <400> 1524 Leu Gly Pro Arg Phe Ser Pro Gly Leu Pro Thr Tyr Ile Arg Tyr Phe 1 5 10 15 Ala Gln Leu Pro Ala Asn Thr Pro Val Leu Gly Thr Thr Ala Thr Ala 20 25 30 Asn Asn Arg Val Val Glu Asp Ile Arg Gln Gln Leu Gly Asp Ile Val 35 40 45 Ile Gln Arg Gly Thr Leu Ala Arg Glu Ser Leu Ala Leu Asp Ala Leu 50 55 60 Val Leu Gly Glu His Ser Ser Arg Leu Ala Trp Leu Ala Thr Val Ile 65 70 75 80 Pro Gln Phe Ser Lys Ser Gly Ile Val Tyr Thr Leu Thr Thr Arg Asp 85 90 95 Ala Glu Leu Val Ala Glu Trp Leu Arg Lys Asn Gly Ile Ser Ala Phe 100 105 110 Ala Tyr Tyr Ser Gly Val Thr Cys Glu Gly Ala Glu Asp Ser Asn Thr 115 120 125 Ala Arg Glu Tyr Leu Glu Gln Ala Leu Leu Ala Asn Lys Ile Lys Val 130 135 140 Leu Val Ala Thr Thr Ala Leu Gly Met Gly Phe Asp Lys Pro Asp Leu 145 150 155 160 Gly Phe Val Ile His Tyr Gln Met Pro Gly Ser Ile Val Gly Tyr Tyr 165 170 175 * <210> 1525 <211> 203 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2764..3372) <400> 1525 Met Glu Lys His Ala Ala Glu Leu Leu Leu Gln Arg Met Leu Gly Asn 1 5 10 15 Thr Thr Ala Thr Phe Arg Glu Gly Gln Trp Glu Ala Ile Asp Ala Val 20 25 30 Val Asn Gln Arg Arg Lys Leu Leu Val Val Gln Arg Thr Gly Trp Gly 35 40 45 Lys Ser Ala Val Tyr Phe Ile Ala Ser Lys Ile Phe Arg Asp Arg Gly 50 55 60 Ala Gly Pro Thr Ile Ile Ile Ser Pro Leu Leu Ala Leu Met Arg Asn 65 70 75 80 Gln Val Ala Ala Ala Glu Arg Leu Gly Ile Thr Ala Glu Thr Leu Asn 85 90 95 Ser Thr Asn Arg Glu Glu Trp Gln Arg Ile Ser Asp Lys Leu Leu Gln 100 105 110 Gly Glu Val Asp Cys Leu Leu Val Ser Pro Glu Arg Leu Ala Asn Gln 115 120 125 Asp Phe Ile Glu Thr Val Leu Tyr Pro Ile Ala Asp His Ile Gly Leu 130 135 140 Leu Val Val Asp Glu Ala His Cys Ile Ser Asp Trp Gly His Asp Phe 145 150 155 160 Arg Pro Asp Tyr Arg Arg Ile Leu Asp Ile Leu Arg Asn Tyr Leu Arg 165 170 175 Ile Pro Leu Phe Trp Val Gln Pro Arg Gln Arg Ile Thr Val Ser Leu 180 185 190 Arg Ile Ser Val Ser Asn Trp Val Thr Leu * 195 200 <210> 1526 <211> 3435 <212> DNA <213> Escherichia coli O157:H7 <400> 1526 cagccccgcc cctgtggaat ttattccact ttgcagaatc acgaataagc gtagcaaaat 60 cttttcgttg tgccgtcaca aaccctgact tatatcagaa tatgactgat gcagcgtcga 120 tattatccgt aatacgtccg agtttcggag tactccaatg atgacattgc cctacccata 180 ttcttcctcc gcacgctttt acgcactgcg cctcctcccc gggcaggaag ttttttccca 240 gctacacgct tttgcacagc agcagcaact tcatgccgcc tggattgcag gctgtaccgg 300 tagcctgact gacatcgcct tgcgctatgc cgggcaagaa ggcaccacgc tcctgaacgg 360 tacattcgaa gtgatctcac taaacggcac gttggaacag agtggtgagc atcttcatct 420 ctgcgtttcc gatccacacg gcacgatgct tggcggtcat atgatgcccg gctgtaccgt 480 gcggaccacg cttgaactgg tgatcggtag ccttgaggaa ctggcgttta gccgccaacc 540 ttgcgcgctt tctggttacg acgagttgca tatttccccc gttaaataac tactttcaga 600 gaggttttct tatggcgcgt agccactttt ccagtcaggc actggtgttg atcgttatat 660 ctatcgccat caatatgatc ggcgggcaac tggccagcat ggtcaaatta cctatatttc 720 tcgactccat cggcacactt attagcgcgg tactgcttgg tccggtgatc gggatgctga 780 ccggcttact gaccaattta ctctggggat tactgaccga cccgatcgct gccgcttttg 840 cccccgtcgc gatggtcatc ggcctggtcg ccggttggct ggcgcgagcg ggttggtttc 900 gcaccctgcc aaaagtcgtt gtcagcggcg tgattattac gcttgcggta acggtcgtcg 960 ctgtaccgct gcgtactgcg ctgttcggcg gtgtcaccgg tagcggagcc gatttgttcg 1020 ttgcctggat gcactcgatg gggcaaaacc tggtggagtc ggtggcgatt acggtgatag 1080 gcgcgaacct ggtcgataaa actcttacag cggtgattgt ctggctttta ctgcgccagc 1140 tgccgattcg caccacgcgc cattttccgg caatggctgc cgtgcgctaa atgcatccat 1200 ttacctcatt aacactatgg gcattggcgg cctgcaccac gcttatcctg cccgcgcaga 1260 ccattttgcc gatctatagc gcggcgacct ttttttgcct tattgcgcta aaggccacgc 1320 ggcggcgggc aaaatatgtc gtctggctga tgttctcgct gggagccggg ctgtggctgg 1380 tacacggtgg ctggctaaca gaatggctaa gcggcacgcc gcgttcgccg gagcgttgga 1440 cgcatgctat tacgctctgg ttgcggattc tggcgattgt ttcaacctca cagttgtgga 1500 tgcagtacgt ccccgtgcaa tgttttatcc gcgctctgtt tgcttctcgc ctgccgccgg 1560 gcgtcgctta tctgtttgcc gggccgttat tggtcgttga gcagttaaaa cggcaattag 1620 cgattattca tgaagcgcag cgtgcccgcg gcgtgccgct ggatgagggc tggtatcagc 1680 gtttacgtgc gatgcccgcg ttaactattc cgctaacaca caatgcgcta aacgatcttg 1740 ctgtccgtgg tgcggcgctg gatatgcggg catttcggat ccacaaccga cgaacaacgt 1800 tgtgggcacc agccgatagc accctacaac gcgtagcgcg ttacaccatg atcttgctga 1860 tgctgacaga attcggagcg tggatatggt tacgttagaa cagttccgtt attgcccgac 1920 acactcaacg catcctccgt tctgttatga ctttcactat gtcaaaccgg ggatggtcgc 1980 catctttggt gacaacggca gtggcaaaag tacgctggca cagctgatgg cgggctggta 2040 tccggacttt ctgccaggag agataacagg cacggggacg ctcctcggta cgcccattgg 2100 gcatctcccg cttaatgaac aatccgccac catccagctc gtccagcaat cgccctattt 2160 gcagctctcc ggctgtacct ttagcgtgga agaagaagtt gcctttgggc cagaaaatct 2220 gtgtcttgct gaagcagaga ttatggcgcg gattgatgcc gccctgactc tgaccgagtg 2280 ccagccgttg cgccatcgtc acccggcaac actctccggt ggagagacac agcgcgtggt 2340 catcgcctgc gccatcgcga tgcagccaaa gctattaatt cttgatgaag cctttagccg 2400 cctgacgccg caggccagcg aaatgctgtt gcagcgctta caacactggg cgtttgaacg 2460 tggttcgctg attattcttt ttgaacgtca tcgcacacct ttcctgaact actgccagca 2520 agcgtggcaa ttgcaaaacg gagcgctcca gccactatgt taacgttaaa tcagatatct 2580 tatcgctggc ctggcgcggc aacggattgt ctttgcgaca tttctctgca actcaaacaa 2640 ggtgaatggt tggcgttgac cggcgacaat ggcgcaggga aatcgacgct gttacgagta 2700 atggcaggtc ttcttacgcc cacagccggt acggttatgc tgcaacaaca ggcgatgaaa 2760 aacctgaaaa accgccagcg cgcggcaaag attggcgtac tgtttcagga agcggaaaac 2820 caactttttc acagcaccgt cgctgacgag atcgcatttg gtttgaaact gcaaaaatgc 2880 ccggcggatg aaatcactca acgtacccat gctgccctgc aatgttgtca gttagcagac 2940 actgccagcg cgcacccgtt ggatctgcat agtgcgcagc gacggatggt cgccgtcgcc 3000 tgcctggaag cactctctcc gccactattg ctgctggacg agccgagtcg ggattttgac 3060 gaaaattggt tgagcgtgtt tgaaagctgg ctggagaagt gccgccagcg aggcacgagc 3120 gtcgtagcaa tcagtcatga cgccgcattt acccggcgtc atttctctcg tgtggtgcga 3180 ctggaagatg gtctaatcag gaacattaat ccaccagacg atattcaccc gtagcggtca 3240 tcattaaggt caaatttgca ggcagactct cttccagcac ccggcgaaca ttcggcccgt 3300 cggtacggtc ataaaaagct tctgcgtctg ccagcgataa ccctcccgcc agcttgcgcc 3360 ccaccagtcg ttcccgcaac gcagtagctg gcgcattgat aaagatcgag aaatcacaaa 3420 attgcgctag ctggc 3435 <210> 1527 <211> 144 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(158..589) <400> 1527 Met Met Thr Leu Pro Tyr Pro Tyr Ser Ser Ser Ala Arg Phe Tyr Ala 1 5 10 15 Leu Arg Leu Leu Pro Gly Gln Glu Val Phe Ser Gln Leu His Ala Phe 20 25 30 Ala Gln Gln Gln Gln Leu His Ala Ala Trp Ile Ala Gly Cys Thr Gly 35 40 45 Ser Leu Thr Asp Ile Ala Leu Arg Tyr Ala Gly Gln Glu Gly Thr Thr 50 55 60 Leu Leu Asn Gly Thr Phe Glu Val Ile Ser Leu Asn Gly Thr Leu Glu 65 70 75 80 Gln Ser Gly Glu His Leu His Leu Cys Val Ser Asp Pro His Gly Thr 85 90 95 Met Leu Gly Gly His Met Met Pro Gly Cys Thr Val Arg Thr Thr Leu 100 105 110 Glu Leu Val Ile Gly Ser Leu Glu Glu Leu Ala Phe Ser Arg Gln Pro 115 120 125 Cys Ala Leu Ser Gly Tyr Asp Glu Leu His Ile Ser Pro Val Lys * 130 135 140 <210> 1528 <211> 193 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(612..1190) <400> 1528 Met Ala Arg Ser His Phe Ser Ser Gln Ala Leu Val Leu Ile Val Ile 1 5 10 15 Ser Ile Ala Ile Asn Met Ile Gly Gly Gln Leu Ala Ser Met Val Lys 20 25 30 Leu Pro Ile Phe Leu Asp Ser Ile Gly Thr Leu Ile Ser Ala Val Leu 35 40 45 Leu Gly Pro Val Ile Gly Met Leu Thr Gly Leu Leu Thr Asn Leu Leu 50 55 60 Trp Gly Leu Leu Thr Asp Pro Ile Ala Ala Ala Phe Ala Pro Val Ala 65 70 75 80 Met Val Ile Gly Leu Val Ala Gly Trp Leu Ala Arg Ala Gly Trp Phe 85 90 95 Arg Thr Leu Pro Lys Val Val Val Ser Gly Val Ile Ile Thr Leu Ala 100 105 110 Val Thr Val Val Ala Val Pro Leu Arg Thr Ala Leu Phe Gly Gly Val 115 120 125 Thr Gly Ser Gly Ala Asp Leu Phe Val Ala Trp Met His Ser Met Gly 130 135 140 Gln Asn Leu Val Glu Ser Val Ala Ile Thr Val Ile Gly Ala Asn Leu 145 150 155 160 Val Asp Lys Thr Leu Thr Ala Val Ile Val Trp Leu Leu Leu Arg Gln 165 170 175 Leu Pro Ile Arg Thr Thr Arg His Phe Pro Ala Met Ala Ala Val Arg 180 185 190 * <210> 1529 <211> 236 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1191..1898) <400> 1529 Met His Pro Phe Thr Ser Leu Thr Leu Trp Ala Leu Ala Ala Cys Thr 1 5 10 15 Thr Leu Ile Leu Pro Ala Gln Thr Ile Leu Pro Ile Tyr Ser Ala Ala 20 25 30 Thr Phe Phe Cys Leu Ile Ala Leu Lys Ala Thr Arg Arg Arg Ala Lys 35 40 45 Tyr Val Val Trp Leu Met Phe Ser Leu Gly Ala Gly Leu Trp Leu Val 50 55 60 His Gly Gly Trp Leu Thr Glu Trp Leu Ser Gly Thr Pro Arg Ser Pro 65 70 75 80 Glu Arg Trp Thr His Ala Ile Thr Leu Trp Leu Arg Ile Leu Ala Ile 85 90 95 Val Ser Thr Ser Gln Leu Trp Met Gln Tyr Val Pro Val Gln Cys Phe 100 105 110 Ile Arg Ala Leu Phe Ala Ser Arg Leu Pro Pro Gly Val Ala Tyr Leu 115 120 125 Phe Ala Gly Pro Leu Leu Val Val Glu Gln Leu Lys Arg Gln Leu Ala 130 135 140 Ile Ile His Glu Ala Gln Arg Ala Arg Gly Val Pro Leu Asp Glu Gly 145 150 155 160 Trp Tyr Gln Arg Leu Arg Ala Met Pro Ala Leu Thr Ile Pro Leu Thr 165 170 175 His Asn Ala Leu Asn Asp Leu Ala Val Arg Gly Ala Ala Leu Asp Met 180 185 190 Arg Ala Phe Arg Ile His Asn Arg Arg Thr Thr Leu Trp Ala Pro Ala 195 200 205 Asp Ser Thr Leu Gln Arg Val Ala Arg Tyr Thr Met Ile Leu Leu Met 210 215 220 Leu Thr Glu Phe Gly Ala Trp Ile Trp Leu Arg * 225 230 235 <210> 1530 <211> 226 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1886..2563) <400> 1530 Met Val Thr Leu Glu Gln Phe Arg Tyr Cys Pro Thr His Ser Thr His 1 5 10 15 Pro Pro Phe Cys Tyr Asp Phe His Tyr Val Lys Pro Gly Met Val Ala 20 25 30 Ile Phe Gly Asp Asn Gly Ser Gly Lys Ser Thr Leu Ala Gln Leu Met 35 40 45 Ala Gly Trp Tyr Pro Asp Phe Leu Pro Gly Glu Ile Thr Gly Thr Gly 50 55 60 Thr Leu Leu Gly Thr Pro Ile Gly His Leu Pro Leu Asn Glu Gln Ser 65 70 75 80 Ala Thr Ile Gln Leu Val Gln Gln Ser Pro Tyr Leu Gln Leu Ser Gly 85 90 95 Cys Thr Phe Ser Val Glu Glu Glu Val Ala Phe Gly Pro Glu Asn Leu 100 105 110 Cys Leu Ala Glu Ala Glu Ile Met Ala Arg Ile Asp Ala Ala Leu Thr 115 120 125 Leu Thr Glu Cys Gln Pro Leu Arg His Arg His Pro Ala Thr Leu Ser 130 135 140 Gly Gly Glu Thr Gln Arg Val Val Ile Ala Cys Ala Ile Ala Met Gln 145 150 155 160 Pro Lys Leu Leu Ile Leu Asp Glu Ala Phe Ser Arg Leu Thr Pro Gln 165 170 175 Ala Ser Glu Met Leu Leu Gln Arg Leu Gln His Trp Ala Phe Glu Arg 180 185 190 Gly Ser Leu Ile Ile Leu Phe Glu Arg His Arg Thr Pro Phe Leu Asn 195 200 205 Tyr Cys Gln Gln Ala Trp Gln Leu Gln Asn Gly Ala Leu Gln Pro Leu 210 215 220 Cys * 225 <210> 1531 <211> 226 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2557..3234) <400> 1531 <210> 1532 <211> 3357 <212> DNA <213> Escherichia coli O157:H7 <400> 1532 ttggatatgg ggtatgtatt ggcttaatga tgttgagctt atcgtcaaaa cgcttacctg 60 agaggtaagc gtttggtgcg tgttattgag aaaaagcgaa ttatttgtag gttgcaatcg 120 taatattgcc tgagaaattt ctccttagat tgcggatatc attatccctt gcccaataat 180 catctttgtg tctataactc tcatcggaat gtacataggg agaatcatct tcagcgtcgt 240 tatggataat attttcgcct ttagtggtat agatataatt agcaacatca aaggtgtcat 300 tcgcgttatt tacgactgcg cctaagacgc aaagggtttg agtgaatccg tattctgaga 360 aatcgacatg ctgatggtaa tttctaccat tcaaagcaac aaaactcgga caaacatcta 420 ttgtatcgcc aacagacgta gcggcgcgac gcacatcaag tgcagcgtta tcgttagcaa 480 catgaaatgc ttgtgaacag gcataaaaca aatttctaat cccggtacga ctggataaac 540 aagaaataat ttttgctatt ttttctggct ttataccatc ctgtactaaa gaatctctca 600 ccagatcaca ttcaccaggt gtgaaaacaa ctttcttgaa tatttcctca taaacatcat 660 aagaaaaata ttcagagaga gtgaaagatt cggtgggatg tgttaaatct gtaatttttt 720 tgctaagtaa ttcacttata gtgctgttta ttttttcacc gcaacataaa acaaatgaac 780 ttccctccag aacttgcctt tctgcatcta caaggagtga gctaaattca tcctcatgaa 840 gcttaagttt ttttatacct gattgatgta aatatttttc tggaattaaa tctttttgtt 900 cccttataag ctctatcatt cggcgttcgg tttgcgtatc aaaagagtat ttcatgttat 960 agttattttt agcaacttcc agcttaagag catttgcagc aactgttaat tctgagattt 1020 gatctttttc aaattgatcg tgatctgata ataaccttat aaactctttt acatttcgac 1080 cactaaaatc catatcccta cactttttat cataacactt tgtttcgcca ttgaactcac 1140 gatacagatc agtgatttta aatttattac ttccggtctg atcaattttt atatagctat 1200 tcatgcctgt aacggcaatc tatgtcttat aattcgcatt ctccgattca ggcgtaacat 1260 gaaaataagg aaccaattta tcactaatat catgccgata gatatgaaat gaatctaaaa 1320 gatataataa aaaacttcga aaaatgtcac gaaaagtgtc atctttaaac cttgccctat 1380 aattatcgag caggccgctt tgttctatca tattaaattt ataaatatta tcctcgagac 1440 ttttgtcgat actctccctt agactctgat tttgaaactg gctattatca ttctctgttt 1500 ccgttggata tgaataactc gtcacactaa ccatagtaac ctcgcaatat gacactttgc 1560 atattttgac attgttagaa gtatcaatgg ctagcatgat aaatatctca atgctaaccg 1620 ctatatttca tttatttcaa taataagact atagtgccgt taatttttat cgatttcccc 1680 aatgcaattg catcactaat actacttatt cactatcaaa aatcgctcat tttttcaaaa 1740 agactgttta cacacagacg gttaacaata cgtgttcacc ttaatgataa acgcgcttta 1800 tcaagaaaaa atcataaatc agcagttgtt gcggcaccgg aaaatgtaaa atcgatttta 1860 tcgcttttgg atttttcttc gtcgacacta ccggtagtaa aataacaaga gcactgaagc 1920 ttcacttcat ttccaacatt attaaccgcc atcaaataca tcttctgact aaacccattt 1980 atagtaaaat caatttcttt aagatacttc ccagtcccaa aaaaggcatt tcctgacttt 2040 tttaaacccg atgttgatga aatggtacca ttcaaactct ttgagagtaa ctcgctaaca 2100 tcttgagatg tattttttaa aaaactctga tagccttgca aaggagaata ataaaaacat 2160 gtaatcccct gagggttgga taagcaagcg gttatttcat caatcttatc atccgtaata 2220 ttaccgtttg attgttttaa taattccctt acctgagcac aatcatcatc attaaagcaa 2280 accagttcaa ccatttgttc aagtgtgttt tgactattct ttggatcttt ttcaattatt 2340 tcaattttgt ctgtaaatat tttaagaata tcttcactta actcaacacc gcagcaagtt 2400 attttagtag cacccttttg ttgactttgt tcttttatag ttcaatgagc atccataatc 2460 atggaatcaa aaaaaacatc agttctttta aaactttcct gaacaggtac atacccttca 2520 tcttttttaa ttcgcagttt taataaatca tatatattac ttaaaattcc tgcaggaatt 2580 tcgtaattaa aatccgtatt cttcataaca atactattaa ctaatttctt cctcaaaacc 2640 gtgtcagcgg aatgtgtttc taacgcagaa gttttttcag acaacgattt aataatagtc 2700 gctacagcca ctcctgaata tggaatttct tttcgtgaag gtttatctct gccaaccagt 2760 gtaatattaa aagacttatc acctgtttgt ttgatttcga tatattcatc ctctccagtt 2820 gccgccaccc aggtacgatt accattattt tccgtgcctg gcatagggtg gaaatagtca 2880 agaatatcgg tgttaatact ccgagaaccg gacatgatgt ttagtattaa gcgctttatt 2940 tcctgcaaca tccattttgc gaaattactg ccaggtgaat attttttctc gttattttta 3000 atatcaagct cagcagcgac atttctattt ttatccaaaa aggtggaagg gcagagattt 3060 gccatcatta ttccgctgtt tataggactt gccataatat acctcacgat gaaccattaa 3120 ttaatagaat gctggtcatg accactggta tagacagcaa tcagaattta acaccatcgc 3180 tgaaaatttt agccctaact gtccccccca ggttaccggt gctgcgactt aaattaacgt 3240 cctgggctaa taaattgtgc ctgagatggt ctctggcaca atttcaccct atatatctgc 3300 acggatctat caaaaatcgc tcatcagtaa ctcccccgag cggtttaatg tcgctcc 3357 <210> 1533 <211> 331 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(101..1093) <400> 1533 Met Asp Phe Ser Gly Arg Asn Val Lys Glu Phe Ile Arg Leu Leu Ser 1 5 10 15 Asp His Asp Gln Phe Glu Lys Asp Gln Ile Ser Glu Leu Thr Val Ala 20 25 30 Ala Asn Ala Leu Lys Leu Glu Val Ala Lys Asn Asn Tyr Asn Met Lys 35 40 45 Tyr Ser Phe Asp Thr Gln Thr Glu Arg Arg Met Ile Glu Leu Ile Arg 50 55 60 Glu Gln Lys Asp Leu Ile Pro Glu Lys Tyr Leu His Gln Ser Gly Ile 65 70 75 80 Lys Lys Leu Lys Leu His Glu Asp Glu Phe Ser Ser Leu Leu Val Asp 85 90 95 Ala Glu Arg Gln Val Leu Glu Gly Ser Ser Phe Val Leu Cys Cys Gly 100 105 110 Glu Lys Ile Asn Ser Thr Ile Ser Glu Leu Leu Ser Lys Lys Ile Thr 115 120 125 Asp Leu Thr His Pro Thr Glu Ser Phe Thr Leu Ser Glu Tyr Phe Ser 130 135 140 Tyr Asp Val Tyr Glu Glu Ile Phe Lys Lys Val Val Phe Thr Pro Gly 145 150 155 160 Glu Cys Asp Leu Val Arg Asp Ser Leu Val Gln Asp Gly Ile Lys Pro 165 170 175 Glu Lys Ile Ala Lys Ile Ile Ser Cys Leu Ser Ser Arg Thr Gly Ile 180 185 190 Arg Asn Leu Phe Tyr Ala Cys Ser Gln Ala Phe His Val Ala Asn Asp 195 200 205 Asn Ala Ala Leu Asp Val Arg Arg Ala Ala Thr Ser Val Gly Asp Thr 210 215 220 Ile Asp Val Cys Pro Ser Phe Val Ala Leu Asn Gly Arg Asn Tyr His 225 230 235 240 Gln His Val Asp Phe Ser Glu Tyr Gly Phe Thr Gln Thr Leu Cys Val 245 250 255 Leu Gly Ala Val Val Asn Asn Ala Asn Asp Thr Phe Asp Val Ala Asn 260 265 270 Tyr Ile Tyr Thr Thr Lys Gly Glu Asn Ile Ile His Asn Asp Ala Glu 275 280 285 Asp Asp Ser Pro Tyr Val His Ser Asp Glu Ser Tyr Arg His Lys Asp 290 295 300 Asp Tyr Trp Ala Arg Asp Asn Asp Ile Arg Asn Leu Arg Arg Asn Phe 305 310 315 320 Ser Gly Asn Ile Thr Ile Ala Thr Tyr Lys * 325 330 <210> 1534 <211> 105 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1220..1534) <400> 1534 Met Val Ser Val Thr Ser Tyr Ser Tyr Pro Thr Glu Thr Glu Asn Asp 1 5 10 15 Asn Ser Gln Phe Gln Asn Gln Ser Leu Arg Glu Ser Ile Asp Lys Ser 20 25 30 Leu Glu Asp Asn Ile Tyr Lys Phe Asn Met Ile Glu Gln Ser Gly Leu 35 40 45 Leu Asp Asn Tyr Arg Ala Arg Phe Lys Asp Asp Thr Phe Arg Asp Ile 50 55 60 Phe Arg Ser Phe Leu Leu Tyr Leu Leu Asp Ser Phe His Ile Tyr Arg 65 70 75 80 His Asp Ile Ser Asp Lys Leu Val Pro Tyr Phe His Val Thr Pro Glu 85 90 95 Ser Glu Asn Ala Asn Tyr Lys Thr * 100 <210> 1535 <211> 161 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1812..2294) <400> 1535 Met Val Glu Leu Val Cys Phe Asn Asp Asp Asp Cys Ala Gln Val Arg 1 5 10 15 Glu Leu Leu Lys Gln Ser Asn Gly Asn Ile Thr Asp Asp Lys Ile Asp 20 25 30 Glu Ile Thr Ala Cys Leu Ser Asn Pro Gln Gly Ile Thr Cys Phe Tyr 35 40 45 Tyr Ser Pro Leu Gln Gly Tyr Gln Ser Phe Leu Lys Asn Thr Ser Gln 50 55 60 Asp Val Ser Glu Leu Leu Ser Lys Ser Leu Asn Gly Thr Ile Ser Ser 65 70 75 80 Thr Ser Gly Leu Lys Lys Ser Gly Asn Ala Phe Phe Gly Thr Gly Lys 85 90 95 Tyr Leu Lys Glu Ile Asp Phe Thr Ile Asn Gly Phe Ser Gln Lys Met 100 105 110 Tyr Leu Met Ala Val Asn Asn Val Gly Asn Glu Val Lys Leu Gln Cys 115 120 125 Ser Cys Tyr Phe Thr Thr Gly Ser Val Asp Glu Glu Lys Ser Lys Ser 130 135 140 Asp Lys Ile Asp Phe Thr Phe Ser Gly Ala Ala Thr Thr Ala Asp Leu 145 150 155 160 * <210> 1536 <211> 218 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2442..3095) <400> 1536 Met Ala Ser Pro Ile Asn Ser Gly Ile Met Met Ala Asn Leu Cys Pro 1 5 10 15 Ser Thr Phe Leu Asp Lys Asn Arg Asn Val Ala Ala Glu Leu Asp Ile 20 25 30 Lys Asn Asn Glu Lys Lys Tyr Ser Pro Gly Ser Asn Phe Ala Lys Trp 35 40 45 Met Leu Gln Glu Ile Lys Arg Leu Ile Leu Asn Ile Met Ser Gly Ser 50 55 60 Arg Ser Ile Asn Thr Asp Ile Leu Asp Tyr Phe His Pro Met Pro Gly 65 70 75 80 Thr Glu Asn Asn Gly Asn Arg Thr Trp Val Ala Ala Thr Gly Glu Asp 85 90 95 Glu Tyr Ile Glu Ile Lys Gln Thr Gly Asp Lys Ser Phe Asn Ile Thr 100 105 110 Leu Val Gly Arg Asp Lys Pro Ser Arg Lys Glu Ile Pro Tyr Ser Gly 115 120 125 Val Ala Val Ala Thr Ile Ile Lys Ser Leu Ser Glu Lys Thr Ser Ala 130 135 140 Leu Glu Thr His Ser Ala Asp Thr Val Leu Arg Lys Lys Leu Val Asn 145 150 155 160 Ser Ile Val Met Lys Asn Thr Asp Phe Asn Tyr Glu Ile Pro Ala Gly 165 170 175 Ile Leu Ser Asn Ile Tyr Asp Leu Leu Lys Leu Arg Ile Lys Lys Asp 180 185 190 Glu Gly Tyr Val Pro Val Gln Glu Ser Phe Lys Arg Thr Asp Val Phe 195 200 205 Phe Asp Ser Met Ile Met Asp Ala His * 210 215 <210> 1537 <211> 3280 <212> DNA <213> Escherichia coli O157:H7 <400> 1537 tgtctggtag aaggatttgc tgtagacgga tttaaccgat tgcccgctgt gacgggtgcc 60 atctgcaagt gtcgtattgg cctgcgtgat atcgaaagaa aaggcaccaa aaagtcctaa 120 atctttacca ataccaaggt tgaaggcctg ataatcttct gcaatttgca ttccgccata 180 aggtgtccag tttccttcca gtccatgcat caagctacct tgtatgaacc tgggggagct 240 ttgcaggtta tttccactac gatattcccc catggcaagc gcataacgcg tatatccagc 300 acgttggaga accggaacag acgaataagg aacatataat gtctgaatac tgccgtctgc 360 ctcttttatg gttacttgca gatcaccacc attggccgca gagttgatat catcaatagt 420 aaaagggccg ggtggaacag tagtctgata aacatcgtat ccgttctgtt ttacactcac 480 ttgtgcggtg ccacgggcaa taccatgaat caccggagcg aaaccatgtt ggctatcggg 540 caacatcgct tctgttgaat ttattttgag gccacgaaag ttcacactat caaaaatatc 600 gccatcggta taactatcac ctaccgttaa ccgtgagcgt aagggaataa tgtcacgttc 660 agccgacgta ttgatatgct gccatttatt gctgtcagat gaattgctac tcccactgtt 720 ataactccac gttgagttat cgcgtagtcg ccaactacca atgttgatgc cactctgtaa 780 attcaaatat gcatagttgg attttcctgc attatggtta ctacgattat taatagaatt 840 accattaaaa ctatagttta gaagcccagc atttattcct tcttcccaca gatcaggaga 900 aacatagccg cgagccattc tgccaacata aatttgcgga acggagagtg acagatgttg 960 ctgaccaaca tcaaactcag ttgatgcgtc gaccaaacga tcctgaagtg gtgtgcatgc 1020 gctgttgtcc ggcacatgtt tttctgctga atgttcctta ttgtctaata acgcagattt 1080 ttttatgcca agactgacaa gaagatctgt actcaggcat gggatgagat ctgcgttatt 1140 atcatctgta ataaaagtaa tatcccgact agtcataaat tcgtcgttca aataaatgtc 1200 gacccgatat gtaccaggtg gtgcctcgcg tcccttagta aaggcggata aatcgacaga 1260 ttcagcaaga tcattgctta aaaaccgtgg attaaaataa tactctgcgt caacgggaaa 1320 taccgcagtt gctaagctaa gggcaatggt aagccgtgca aagcgaggca gtagtaacac 1380 ctgatgcata cgatatgcct taaatgcggc acgaaaggct gtcattatta attccgattg 1440 agtttattat taattaggtc actggcttac tgcatggttg ccttaatacg cggagttaat 1500 gcgccgtaat cattgatcgt ctgaaaactg atatccccgg tggcagcatg cgggatatcc 1560 accgacactt caccttttgg cggcaccatg gtgtttggga gattgctatt tcctgctttc 1620 atatttgtta cggtaatgaa gtagggcgtt ggattaataa gagtgagatt gctaccgctg 1680 cgacgaaacc gaagcattgc aggcgcttct tcaggtgcca ttgccaggtt cgtgggccga 1740 taaaacattt ttatgcggct aataattgcc agctgtaatg tattctcatt cttctggtct 1800 ttttccatag caggaatagc tttaacatta acccagaaca ggctttcacg gtcgccgggt 1860 aactgatgat tagtggcgtt gattatccgc agcgtattct cttttttacc ttgcatggaa 1920 aaaagaggtg gggtaatgac aaactgggtg tctttttggt caccagcatt ttctatccat 1980 gactgaatga gatagacact ggcaggatca ttattcgtga caggcaataa aacctgtttc 2040 tggtttgccg gataaattac ccgcgtcgca cccagtgcga cagctgcgtt ggcaacggtg 2100 ctatggcaag caaagagcaa taaaagtaac actgtcgcca taaaggaaat agagtagggg 2160 gtacgcgtag tttgcatctg atgcattctc catgtgttaa gaggataagc gggaaaaccg 2220 ttacatcaga caatcggtaa atgttgctaa tacattggcg agtcaccggg tttccagact 2280 taatgcgttt gtaataaagg ttggttctct tttaatagga aaaccttgct aaaaagtaaa 2340 tatttttaat aacagtaagt ttaactactg ttgtttattg aacgtttaga tattatgtga 2400 tttttcatag cgctccaaat acaaaccact catcattaat aatgagattc acattggtga 2460 attgctcggg tgtgcgtagc catgccacac acaccctgtt ttaatttcag atgccgtata 2520 gccaccttaa tattgaatta tagatattga actttgaagg tcgcatctgc gtttgcagta 2580 ccagctacgg actgcccgag agcaatataa cgagcctgga atggtagtat attcgtgcca 2640 tcaatcaagt cggttttagc actaaaagtg gccccatcaa gtattaatac ctcacccgta 2700 cggtccaaaa tttgaatacc gacattttgg gcagagcctg ccgctgaact ctgcagcgct 2760 aacgtatcgt cattactggt gacagtagta cccaggaatg caacagctgc attactggaa 2820 acattggtat cacaatcatt cagcttgata ttgaagccaa cggcggagct gaggtcaccc 2880 gctttagcca ggcgagaaga acgaacctga cccagctcaa ccgtttggtt cattgattcg 2940 gaatcaatcg cacaagcggc atttaccact tcacctttaa aatgaataac accgccatta 3000 acagtggtcg ttactgattc atcaccctcg gctgcgctta ccgcagcaga cgacatcgcc 3060 aacacagaaa cgacaatcat accaacatgt ttgagtttca taattctcca aaatttatat 3120 ttaagtagct gaataaagag agttaacaat taagtcattc tgttattgct tataaaacaa 3180 gaatcattct tgattggttg ttgccctgag aatatagttt ccagggttat tacatttcac 3240 gaagaacgat aatatcttta aatcacaagg acacctaatc 3280 <210> 1538 <211> 237 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1467..2177) <400> 1538 Met Gln Thr Thr Arg Thr Pro Tyr Ser Ile Ser Phe Met Ala Thr Val 1 5 10 15 Leu Leu Leu Leu Leu Phe Ala Cys His Ser Thr Val Ala Asn Ala Ala 20 25 30 Val Ala Leu Gly Ala Thr Arg Val Ile Tyr Pro Ala Asn Gln Lys Gln 35 40 45 Val Leu Leu Pro Val Thr Asn Asn Asp Pro Ala Ser Val Tyr Leu Ile 50 55 60 Gln Ser Trp Ile Glu Asn Ala Gly Asp Gln Lys Asp Thr Gln Phe Val 65 70 75 80 Ile Thr Pro Pro Leu Phe Ser Met Gln Gly Lys Lys Glu Asn Thr Leu 85 90 95 Arg Ile Ile Asn Ala Thr Asn His Gln Leu Pro Gly Asp Arg Glu Ser 100 105 110 Leu Phe Trp Val Asn Val Lys Ala Ile Pro Ala Met Glu Lys Asp Gln 115 120 125 Lys Asn Glu Asn Thr Leu Gln Leu Ala Ile Ile Ser Arg Ile Lys Met 130 135 140 Phe Tyr Arg Pro Thr Asn Leu Ala Met Ala Pro Glu Glu Ala Pro Ala 145 150 155 160 Met Leu Arg Phe Arg Arg Ser Gly Ser Asn Leu Thr Leu Ile Asn Pro 165 170 175 Thr Pro Tyr Phe Ile Thr Val Thr Asn Met Lys Ala Gly Asn Ser Asn 180 185 190 Leu Pro Asn Thr Met Val Pro Pro Lys Gly Glu Val Ser Val Asp Ile 195 200 205 Pro His Ala Ala Thr Gly Asp Ile Ser Phe Gln Thr Ile Asn Asp Tyr 210 215 220 Gly Ala Leu Thr Pro Arg Ile Lys Ala Thr Met Gln * 225 230 235 <210> 1539 <211> 188 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2538..3101) <400> 1539 Met Lys Leu Lys His Val Gly Met Ile Val Val Ser Val Leu Ala Met 1 5 10 15 Ser Ser Ala Ala Val Ser Ala Ala Glu Gly Asp Glu Ser Val Thr Thr 20 25 30 Thr Val Asn Gly Gly Val Ile His Phe Lys Gly Glu Val Val Asn Ala 35 40 45 Ala Cys Ala Ile Asp Ser Glu Ser Met Asn Gln Thr Val Glu Leu Gly 50 55 60 Gln Val Arg Ser Ser Arg Leu Ala Lys Ala Gly Asp Leu Ser Ser Ala 65 70 75 80 Val Gly Phe Asn Ile Lys Leu Asn Asp Cys Asp Thr Asn Val Ser Ser 85 90 95 Asn Ala Ala Val Ala Phe Leu Gly Thr Thr Val Thr Ser Asn Asp Asp 100 105 110 Thr Leu Ala Leu Gln Ser Ser Ala Ala Gly Ser Ala Gln Asn Val Gly 115 120 125 Ile Gln Ile Leu Asp Arg Thr Gly Glu Val Leu Ile Leu Asp Gly Ala 130 135 140 Thr Phe Ser Ala Lys Thr Asp Leu Ile Asp Gly Thr Asn Ile Leu Pro 145 150 155 160 Phe Gln Ala Arg Tyr Ile Ala Leu Gly Gln Ser Val Ala Gly Thr Ala 165 170 175 Asn Ala Asp Ala Thr Phe Lys Val Gln Tyr Leu * 180 185 <210> 1540 <211> 2934 <212> DNA <213> Escherichia coli O157:H7 <400> 1540 gaggccgggt aaagcaaagc cactacccgg cactttttat tagcgcttac cttccgccag 60 cagcggcggg atgctcggca ccattggcgc gtcatcaata tctttctgcg tcatgcggaa 120 cgcttcggga taatgttcgc ggctggtacg gcgcagcggt tcggtatcgc gccaggtata 180 aaggcaatgc tggcactgat ataccgtcca gacatctttc accggcgatt tcgccatcac 240 ttcaatctgt tcatcggcac aacgtggaca aatcatcttg ttctccttat ttacgtgcgg 300 ccagcatagc ggtcagtttt tcagcccagg ctttggtttc cggcaaatcc accaccggct 360 ggctgtagtg accacggttg tccggggcga caggcgtggt ggcgtcgata atcagcttgt 420 cggtgatccc cgccgggctt gagccagggt cgagttccag cacggacata ttcggcaact 480 gcaccaaatc ccctgccgga tttactttcg aggagagcgc ccacatcacc tgcggcaggt 540 tgaacgggtc aacgtcttca tcgaccataa tcaccatctt tacgtagccc agaccgtgcg 600 gcgtggtcat cgcacgcagg cccaccgcgc gggcaaagcc gccgtagcgt tttttggtgg 660 agataatcgc cagcaggccg tgggtgtaca tggcgtttac cgcctgcact tccgggaact 720 cggctttcag ttgttgatac agcggcacac aggtggctgg ccccatcagg tagtcgattt 780 cggtccacgg catgccgagg tacagcgatt cgaaaatcgg cctggtgcgg taagagactt 840 tatcgatacg caccacggtc atgttacgcc cgccggagta gtgcccggta aactcaccga 900 acggcccttc gatttcgcgt ttgcggcttt cgataacccc ttcgaggatc acttctgaac 960 cccacggcac atcaaaacca gtcaatggcg cggtggcgat cgggtacggg ctttcgcgca 1020 gcgcgcctgc catttcatac tcagactgat cgtatttcag cggcgtggcg cccataaggg 1080 tgatgatcgg atcgttaccc agggtgatgg caatcggcag atcttcaccg cgctcttccg 1140 ctttatgcag atgcagggcg atatcgtgca tcggcaccgg ttgcaggccg agcttacgct 1200 tgcccttcac ttccatgcgg tagataccga cgttctgctt gccgaagtta tccgggtcga 1260 gcggatcgcg ggaaaccacg cacgctttgt cgagatagaa accgccatca ccgtcgttta 1320 aacgaaacag cggcaggata tcgaacagat taatctcgtc accatcgacg gtgttctgcg 1380 cccaggctgg attggcgcgg cgctccgggg cgatcgggaa gttatcccag cggcggataa 1440 actcatcaat ctgtttttta accggggtgt ttggcggcag gcccaaggaa atcgcgtggt 1500 tctgccagga accgatggta ttcatcgcca cgcgggcatc ggtaaaaccg cgaatattat 1560 caaaccacag cgccggtgca ccatcgccga tacgcccggt ggcgttggca gcggcagcca 1620 gatccggttc cgcgttcacc tcttcgctga ttttcagtaa ctggccgtgg tcatcaagcg 1680 cctgtaaaaa gctgcgtaaa tcatcaaatg ccattattca ttctcctgag aaaaattccg 1740 ggcctgcggc aatccttgcc agcgcctggc gtagggatgt tcaaggccaa attgatccag 1800 cacgcgggct accacgtggt ggacaatgtc atctaccgtt tcgggatggt tataaaaggc 1860 aggcatcggc ggcaccatcg ccacgcccat gcgtgaaagt gcgagcatat tttcgagatg 1920 gatggtgcta agcggcattt cacgcggcac cagcaccagt ttgcggcctt ctttaagcac 1980 gacgtccgcc gcgcgcccta ccaggccatc agcgtaacca gcgcggatac cggcgagcgt 2040 tttcatactg cacggaataa cgatcatgcc gtctgtacga aaggaacctg aggagatggt 2100 cgccgcctga tccgccgggt tatggctgaa gtcagcgagg gcagcaacat cgcgggcgct 2160 gtaaggcgtt tccagttcaa tggtggtttt cgcccacttc gacatcacca gatgagtctc 2220 gacattcggc atctcccgca gcgcttgcag taatgccaca ccaagaggcg caccggtagc 2280 ccctgtcatc ccgacgatca gtttcattgc ttactctctt aattgttcgt atacgaacat 2340 tattattaaa atacgcctct gttctcattg cggcaagcac tgaaaagtaa caacatcccc 2400 ttcgtcactg aaaaaccgct atgatagcgg cagatagttt gcccggagtt tacatgacgt 2460 tacgaaataa agcgttccat cagttacgac agctttttca gcagcacacg gctcgctggc 2520 agcacgagtt acctgacctg accaaaccac agtatgcggt gatgcgcgcc attgctgata 2580 agcctggtat cgaacaggtg gcactgatag aagcagcagt cagcaccaaa gcaacgttgg 2640 cagaaatgtt ggcaagaatg gagaatcgtg gcttagtcag acgtgaacat gatgccgctg 2700 acaagcggcg tcgctttgtc tggctgactg ccgaaggaga aaagatactt gctgcggcga 2760 taccgattgg tgacagcgtg gatgaggaat ttttggggcg tttgagtgca gaagagcagg 2820 agctgtttgt gcagctggtg cgcaagatga tgaacacata ggatgcaaat tgccgggtag 2880 gacgctgacg tgtcttatcc aggcgacaaa aacacaagct tcccaaacaa aaga 2934 <210> 1541 <211> 79 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(40..276) <400> 1541 Met Ile Cys Pro Arg Cys Ala Asp Glu Gln Ile Glu Val Met Ala Lys 1 5 10 15 Ser Pro Val Lys Asp Val Trp Thr Val Tyr Gln Cys Gln His Cys Leu 20 25 30 Tyr Thr Trp Arg Asp Thr Glu Pro Leu Arg Arg Thr Ser Arg Glu His 35 40 45 Tyr Pro Glu Ala Phe Arg Met Thr Gln Lys Asp Ile Asp Asp Ala Pro 50 55 60 Met Val Pro Ser Ile Pro Pro Leu Leu Ala Glu Gly Lys Arg * 65 70 75 <210> 1542 <211> 476 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(287..1714) <400> 1542 Met Ala Phe Asp Asp Leu Arg Ser Phe Leu Gln Ala Leu Asp Asp His 1 5 10 15 Gly Gln Leu Leu Lys Ile Ser Glu Glu Val Asn Ala Glu Pro Asp Leu 20 25 30 Ala Ala Ala Ala Asn Ala Thr Gly Arg Ile Gly Asp Gly Ala Pro Ala 35 40 45 Leu Trp Phe Asp Asn Ile Arg Gly Phe Thr Asp Ala Arg Val Ala Met 50 55 60 Asn Thr Ile Gly Ser Trp Gln Asn His Ala Ile Ser Leu Gly Leu Pro 65 70 75 80 Pro Asn Thr Pro Val Lys Lys Gln Ile Asp Glu Phe Ile Arg Arg Trp 85 90 95 Asp Asn Phe Pro Ile Ala Pro Glu Arg Arg Ala Asn Pro Ala Trp Ala 100 105 110 Gln Asn Thr Val Asp Gly Asp Glu Ile Asn Leu Phe Asp Ile Leu Pro 115 120 125 Leu Phe Arg Leu Asn Asp Gly Asp Gly Gly Phe Tyr Leu Asp Lys Ala 130 135 140 Cys Val Val Ser Arg Asp Pro Leu Asp Pro Asp Asn Phe Gly Lys Gln 145 150 155 160 Asn Val Gly Ile Tyr Arg Met Glu Val Lys Gly Lys Arg Lys Leu Gly 165 170 175 Leu Gln Pro Val Pro Met His Asp Ile Ala Leu His Leu His Lys Ala 180 185 190 Glu Glu Arg Gly Glu Asp Leu Pro Ile Ala Ile Thr Leu Gly Asn Asp 195 200 205 Pro Ile Ile Thr Leu Met Gly Ala Thr Pro Leu Lys Tyr Asp Gln Ser 210 215 220 Glu Tyr Glu Met Ala Gly Ala Leu Arg Glu Ser Pro Tyr Pro Ile Ala 225 230 235 240 Thr Ala Pro Leu Thr Gly Phe Asp Val Pro Trp Gly Ser Glu Val Ile 245 250 255 Leu Glu Gly Val Ile Glu Ser Arg Lys Arg Glu Ile Glu Gly Pro Phe 260 265 270 Gly Glu Phe Thr Gly His Tyr Ser Gly Gly Arg Asn Met Thr Val Val 275 280 285 Arg Ile Asp Lys Val Ser Tyr Arg Thr Arg Pro Ile Phe Glu Ser Leu 290 295 300 Tyr Leu Gly Met Pro Trp Thr Glu Ile Asp Tyr Leu Met Gly Pro Ala 305 310 315 320 Thr Cys Val Pro Leu Tyr Gln Gln Leu Lys Ala Glu Phe Pro Glu Val 325 330 335 Gln Ala Val Asn Ala Met Tyr Thr His Gly Leu Leu Ala Ile Ile Ser 340 345 350 Thr Lys Lys Arg Tyr Gly Gly Phe Ala Arg Ala Val Gly Leu Arg Ala 355 360 365 Met Thr Thr Pro His Gly Leu Gly Tyr Val Lys Met Val Ile Met Val 370 375 380 Asp Glu Asp Val Asp Pro Phe Asn Leu Pro Gln Val Met Trp Ala Leu 385 390 395 400 Ser Ser Lys Val Asn Pro Ala Gly Asp Leu Val Gln Leu Pro Asn Met 405 410 415 Ser Val Leu Glu Leu Asp Pro Gly Ser Ser Pro Ala Gly Ile Thr Asp 420 425 430 Lys Leu Ile Ile Asp Ala Thr Thr Pro Val Ala Pro Asp Asn Arg Gly 435 440 445 His Tyr Ser Gln Pro Val Val Asp Leu Pro Glu Thr Lys Ala Trp Ala 450 455 460 Glu Lys Leu Thr Ala Met Leu Ala Ala Arg Lys * 465 470 475 <210> 1543 <211> 198 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1714..2307) <400> 1543 Met Lys Leu Ile Val Gly Met Thr Gly Ala Thr Gly Ala Pro Leu Gly 1 5 10 15 Val Ala Leu Leu Gln Ala Leu Arg Glu Met Pro Asn Val Glu Thr His 20 25 30 Leu Val Met Ser Lys Trp Ala Lys Thr Thr Ile Glu Leu Glu Thr Pro 35 40 45 Tyr Ser Ala Arg Asp Val Ala Ala Leu Ala Asp Phe Ser His Asn Pro 50 55 60 Ala Asp Gln Ala Ala Thr Ile Ser Ser Gly Ser Phe Arg Thr Asp Gly 65 70 75 80 Met Ile Val Ile Pro Cys Ser Met Lys Thr Leu Ala Gly Ile Arg Ala 85 90 95 Gly Tyr Ala Asp Gly Leu Val Gly Arg Ala Ala Asp Val Val Leu Lys 100 105 110 Glu Gly Arg Lys Leu Val Leu Val Pro Arg Glu Met Pro Leu Ser Thr 115 120 125 Ile His Leu Glu Asn Met Leu Ala Leu Ser Arg Met Gly Val Ala Met 130 135 140 Val Pro Pro Met Pro Ala Phe Tyr Asn His Pro Glu Thr Val Asp Asp 145 150 155 160 Ile Val His His Val Val Ala Arg Val Leu Asp Gln Phe Gly Leu Glu 165 170 175 His Pro Tyr Ala Arg Arg Trp Gln Gly Leu Pro Gln Ala Arg Asn Phe 180 185 190 Ser Gln Glu Asn Glu * 195 <210> 1544 <211> 136 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2454..2861) <400> 1544 Met Thr Leu Arg Asn Lys Ala Phe His Gln Leu Arg Gln Leu Phe Gln 1 5 10 15 Gln His Thr Ala Arg Trp Gln His Glu Leu Pro Asp Leu Thr Lys Pro 20 25 30 Gln Tyr Ala Val Met Arg Ala Ile Ala Asp Lys Pro Gly Ile Glu Gln 35 40 45 Val Ala Leu Ile Glu Ala Ala Val Ser Thr Lys Ala Thr Leu Ala Glu 50 55 60 Met Leu Ala Arg Met Glu Asn Arg Gly Leu Val Arg Arg Glu His Asp 65 70 75 80 Ala Ala Asp Lys Arg Arg Arg Phe Val Trp Leu Thr Ala Glu Gly Glu 85 90 95 Lys Ile Leu Ala Ala Ala Ile Pro Ile Gly Asp Ser Val Asp Glu Glu 100 105 110 Phe Leu Gly Arg Leu Ser Ala Glu Glu Gln Glu Leu Phe Val Gln Leu 115 120 125 Val Arg Lys Met Met Asn Thr * 130 135 <210> 1545 <211> 2903 <212> DNA <213> Escherichia coli O157:H7 <400> 1545 aaaaaacagg cttgccgcca cgatggcgca aagaaaaacg ataaaggtga tgcgcttttt 60 caacttattg ctccttatta ttgctttttt ctcgtcaaat tcagtgcgac agataaggag 120 tatacggatg aagcttaatg aattcttaac gcgggcgatg aaatagtaaa cgccgcaggg 180 ggcggcggtt gtctctggat ggcagaacat tttcagctta catcgactga taaatgcgcc 240 tcatctatga atgatagatg aggcggttaa cgtttaaatg ttaatctata tcgtctgcca 300 tacccactct gtttgggtga ttaatgaact attcttcaac tatatatgtt ggctgataag 360 acgttaaacc cggaatggaa aatctcctat tcacttcttt ctttaaacgg gcttgattaa 420 aactgttact gtcctgttgc tcggtactgt tcttggcttg tttatcggta ctgtcattga 480 cctgtttatc gatattgtca ttggcttgtt tatcggtact gtcattggct tgttgcaccg 540 tactgtcaat ggattgttgc accgtactgt cattggcctg tttatcggta ctgtcaatgg 600 attgtttctc ggtactgtta ttggcttgat tcacgatatt atcattgttc agatatgctc 660 cctcaagata gacatttttc gctctgacat tgtaaaaaca ggtattttta aaaagcgttt 720 ttataaatat tgtattgtca aaccatgcgt agtcaaatag gatattcgaa caatttgcac 780 cagtacaatt agtattgtag aattttgcat tcgaaaagtt tgcattagag attttacaat 840 ttgttaaatt agcgtttgaa aagttggtat acatgcagag aataccagta agattatatt 900 ctgaaagatc ttttcccgat agatcggaat aatttagtat tgcgccagta agaattactt 960 taggtgttcc cggtatttga ggtgttccag gtattccagg tattttagat gtttcatata 1020 gaatcacggt tgtgaaatct atgtgttcaa gatacgcgtt actaaggtca cttccagtaa 1080 aggttacgcc agtgagaact tttccgttga agttactgtt tcgtagattt gcgtttttga 1140 aatttacata agtcaagtgg cgaactttac gaaaatcatt attttctaat gaggcatttt 1200 cgaattctgc attacgcaga tcacaatcgg taaaatccac gccttcacag atcgtaccgg 1260 agaacttggc atttctaaga atgctgccat taaaattgac attccttagc gccattttcg 1320 acaagtctat gtcggttaaa tccatctctg ctaaattcaa cccttcgata caccgttgac 1380 ccgttgcatc ttcaggaata gcagtgctaa tagtattgat gacaacatca cctatcttga 1440 aggtcattgt aattcctgca tcagagatag agagttttcg cgtaagacgt tcactcttat 1500 ctccagtgat actcttctga gcaacgtaaa agcgctcgca tgtctcacaa aatcttttcc 1560 agctctcatt tggggtcaga ttattgtccg ggaggaaatt agcaatgcta taaagatcgt 1620 tcaggacgct acttcttatt tcaggagagg cgcattcaat aatttcagag gtggatattg 1680 tatttttaat tttatctata ttatccgtga gatttcgtga tcctgctata tttggctgct 1740 ggtggttttc tttgtagtat tgcagcaaat tttcccattg taagtttgta aacgagaaag 1800 tttcagtctt gttattgtta tcccgtatgg ttaattgatt ttctactggg tcaaaagaaa 1860 tcatgaagtt attcaggtgt tgatattgat gagtggcatc taatttcact tcaaatgaat 1920 ttgaactttt gcaggcatgt tttaaaaact tttcacaggg aaggtgttga tctttatcta 1980 cttgttgtgg gtcattgtgc aaaacagaga aaatactctc tttcaaattg ttcttgtcaa 2040 tatagattgg tagttgcgct ttttgttcca ttattttaat aaactgctgc agttgctcgg 2100 ttttaacatt gcagtgatga cttatatctt tatctttatc tttatcttta tctttatctt 2160 tatctttatc tttaacagtt aatacgcttt cattatcatc ttgtcgatta aatattattt 2220 ttagatcgcc atcgtcaaac tcatgtaaac catttctttt ggttctgccg atgatttgtt 2280 ctgttgttga tgaatatcta tttaaggtta attcaagatt gtcgggatta gagataaggt 2340 gaataaaaag attcagtaca cgcttaatca aaccatcatt caaatgattt atatcataat 2400 taatttgttt ttgtatggtt tcaatttccg tgttaatatc aaatggtagg ttgttttttt 2460 catggcaagc ttttagtccc gaatacatgc cgagtgttgg gaaaatatct ttgtatatgt 2520 taaataggga gcccatattt ttatccttga actgtgaaat attcttctaa atctaaaata 2580 atcagggggt ggggaaagat aagctttgca cagaaactta tcttttaaca ttacaacacc 2640 cggtaatcat tttatttctc tatgcatgat tatgggttta agtataattc aatgtatatt 2700 gtattttaga cgcgcaatag gaaggtgcta tcaaaaatcg ctcattttgt ggatgggaaa 2760 tatttcacgg caggcgagat atttactaca acttccttca tgcaggatta tgcgcagcca 2820 attatccggt tggtatattt aaagatccta ttgcctggtt gacgcttctg catcgtaatg 2880 caccacgcac tgccagtcgc tgc 2903 <210> 1546 <211> 736 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(329..2536) <400> 1546 Met Gly Ser Leu Phe Asn Ile Tyr Lys Asp Ile Phe Pro Thr Leu Gly 1 5 10 15 Met Tyr Ser Gly Leu Lys Ala Cys His Glu Lys Asn Asn Leu Pro Phe 20 25 30 Asp Ile Asn Thr Glu Ile Glu Thr Ile Gln Lys Gln Ile Asn Tyr Asp 35 40 45 Ile Asn His Leu Asn Asp Gly Leu Ile Lys Arg Val Leu Asn Leu Phe 50 55 60 Ile His Leu Ile Ser Asn Pro Asp Asn Leu Glu Leu Thr Leu Asn Arg 65 70 75 80 Tyr Ser Ser Thr Thr Glu Gln Ile Ile Gly Arg Thr Lys Arg Asn Gly 85 90 95 Leu His Glu Phe Asp Asp Gly Asp Leu Lys Ile Ile Phe Asn Arg Gln 100 105 110 Asp Asp Asn Glu Ser Val Leu Thr Val Lys Asp Lys Asp Lys Asp Lys 115 120 125 Asp Lys Asp Lys Asp Lys Asp Lys Asp Ile Ser His His Cys Asn Val 130 135 140 Lys Thr Glu Gln Leu Gln Gln Phe Ile Lys Ile Met Glu Gln Lys Ala 145 150 155 160 Gln Leu Pro Ile Tyr Ile Asp Lys Asn Asn Leu Lys Glu Ser Ile Phe 165 170 175 Ser Val Leu His Asn Asp Pro Gln Gln Val Asp Lys Asp Gln His Leu 180 185 190 Pro Cys Glu Lys Phe Leu Lys His Ala Cys Lys Ser Ser Asn Ser Phe 195 200 205 Glu Val Lys Leu Asp Ala Thr His Gln Tyr Gln His Leu Asn Asn Phe 210 215 220 Met Ile Ser Phe Asp Pro Val Glu Asn Gln Leu Thr Ile Arg Asp Asn 225 230 235 240 Asn Asn Lys Thr Glu Thr Phe Ser Phe Thr Asn Leu Gln Trp Glu Asn 245 250 255 Leu Leu Gln Tyr Tyr Lys Glu Asn His Gln Gln Pro Asn Ile Ala Gly 260 265 270 Ser Arg Asn Leu Thr Asp Asn Ile Asp Lys Ile Lys Asn Thr Ile Ser 275 280 285 Thr Ser Glu Ile Ile Glu Cys Ala Ser Pro Glu Ile Arg Ser Ser Val 290 295 300 Leu Asn Asp Leu Tyr Ser Ile Ala Asn Phe Leu Pro Asp Asn Asn Leu 305 310 315 320 Thr Pro Asn Glu Ser Trp Lys Arg Phe Cys Glu Thr Cys Glu Arg Phe 325 330 335 Tyr Val Ala Gln Lys Ser Ile Thr Gly Asp Lys Ser Glu Arg Leu Thr 340 345 350 Arg Lys Leu Ser Ile Ser Asp Ala Gly Ile Thr Met Thr Phe Lys Ile 355 360 365 Gly Asp Val Val Ile Asn Thr Ile Ser Thr Ala Ile Pro Glu Asp Ala 370 375 380 Thr Gly Gln Arg Cys Ile Glu Gly Leu Asn Leu Ala Glu Met Asp Leu 385 390 395 400 Thr Asp Ile Asp Leu Ser Lys Met Ala Leu Arg Asn Val Asn Phe Asn 405 410 415 Gly Ser Ile Leu Arg Asn Ala Lys Phe Ser Gly Thr Ile Cys Glu Gly 420 425 430 Val Asp Phe Thr Asp Cys Asp Leu Arg Asn Ala Glu Phe Glu Asn Ala 435 440 445 Ser Leu Glu Asn Asn Asp Phe Arg Lys Val Arg His Leu Thr Tyr Val 450 455 460 Asn Phe Lys Asn Ala Asn Leu Arg Asn Ser Asn Phe Asn Gly Lys Val 465 470 475 480 Leu Thr Gly Val Thr Phe Thr Gly Ser Asp Leu Ser Asn Ala Tyr Leu 485 490 495 Glu His Ile Asp Phe Thr Thr Val Ile Leu Tyr Glu Thr Ser Lys Ile 500 505 510 Pro Gly Ile Pro Gly Thr Pro Gln Ile Pro Gly Thr Pro Lys Val Ile 515 520 525 Leu Thr Gly Ala Ile Leu Asn Tyr Ser Asp Leu Ser Gly Lys Asp Leu 530 535 540 Ser Glu Tyr Asn Leu Thr Gly Ile Leu Cys Met Tyr Thr Asn Phe Ser 545 550 555 560 Asn Ala Asn Leu Thr Asn Cys Lys Ile Ser Asn Ala Asn Phe Ser Asn 565 570 575 Ala Lys Phe Tyr Asn Thr Asn Cys Thr Gly Ala Asn Cys Ser Asn Ile 580 585 590 Leu Phe Asp Tyr Ala Trp Phe Asp Asn Thr Ile Phe Ile Lys Thr Leu 595 600 605 Phe Lys Asn Thr Cys Phe Tyr Asn Val Arg Ala Lys Asn Val Tyr Leu 610 615 620 Glu Gly Ala Tyr Leu Asn Asn Asp Asn Ile Val Asn Gln Ala Asn Asn 625 630 635 640 Ser Thr Glu Lys Gln Ser Ile Asp Ser Thr Asp Lys Gln Ala Asn Asp 645 650 655 Ser Thr Val Gln Gln Ser Ile Asp Ser Thr Val Gln Gln Ala Asn Asp 660 665 670 Ser Thr Asp Lys Gln Ala Asn Asp Asn Ile Asp Lys Gln Val Asn Asp 675 680 685 Ser Thr Asp Lys Gln Ala Lys Asn Ser Thr Glu Gln Gln Asp Ser Asn 690 695 700 Ser Phe Asn Gln Ala Arg Leu Lys Lys Glu Val Asn Arg Arg Phe Ser 705 710 715 720 Ile Pro Gly Leu Thr Ser Tyr Gln Pro Thr Tyr Ile Val Glu Glu * 725 730 735 <210> 1547 <211> 2852 <212> DNA <213> Escherichia coli O157:H7 <400> 1547 actccacttc cgtatctggc ttctattttt gctacgccac tggcaataat atcccaacgc 60 aaaaccaagc tgtgcactta tcggaccgac aaagtcgatc cactgttgag accaaaatgg 120 cgaaaaattc agtgggagcc agacaactgt cagaaagaaa ctgcgcatat tttccagcaa 180 agcaatttgc gctggcgcga cataaaaaat gatattccac aggagcaacc agaaataaac 240 tggtgcaaat accagccaac aatgcagtct gcttttcaat tcaggtggcg ttctgcgcgc 300 aaattgccaa ccaacgccca ccattgcaca gaagaaaagc gcatattcag ccgataacca 360 tagttgtaat tgcagaaggg aaatacgcct gtgcatgagc gggattgaga acagtatttc 420 tcccagaaaa ctcagcgtga ttacacaggc agccagcgca accaccgtcg gccacaccaa 480 caacggtaca ataacaaagc cgagaaataa cggataaata taaagtctga ttatattcat 540 cattattgtc ctgatgattc gggggatgct tcatacagcg gcacataccc cacatcctct 600 accaactgtt gcccctgctg acttataaac cagtcaacaa atttctgcgt ttccggcgtg 660 ggattttcac gcgtcaccat ataggcatcc acaatgtatg gataagtgcc gttgcggata 720 ttttcctcgg taggcgcaac gccatttata gccaaaagtt taatctgctt gcgcattttg 780 agcatattgt cattcatacg agtgacgtaa tagtggaagg tgtacccaat ggaagatggc 840 gtgttttgat agtcggcaac ttcagtaatt aaaccgccca taagatcaat cacagtggat 900 tttttagctg gcagcattgg ggtgtcttgc ataaccaacc ccttcataat cgtttggctt 960 ccagaatctt cagggcgctg ccagactttt atatgttcgt cactaccacc tactttattc 1020 cagcggctag ttttgccgct aaaaatatct ttaacctggt gctcagagag agaatttacc 1080 gggttattaa tatcaacgat aaagacaaag gcttcgcggg cgaaagcggt atatttcagt 1140 ttaacacccg cttcttctgc acgttttttc tgtccttccg acggttgtgc aacaaaaata 1200 accgtcgcgg aacctttaat cagactatcg taggcttcag ctgttcgggt ttgctgcaaa 1260 ccatacgcct gccaggccag cgaggttcga tccttatctt ttggctcggg tactaattta 1320 taatacgcgg aggcatacag cgggtataag gctgtagcgc cgtacactct cggccatctt 1380 gaccaatcat cgctgtaacg taatgcaggt tgcccccgca gagacgtcag tccatggctc 1440 tcttcttccc tgacgctgtt atagtaccct tcccggtcga cacatcccgc cagtaacgcc 1500 gtgcctaata gtaaaacacc ggtgaattta ttcatctcgc tgattccttt ctctcgagcg 1560 ttattccatt gttagataca gcggcacata tcccacatct tctaccagac tctgcccctg 1620 cggcgttaaa aaccattcga ccagtttttg tgtttctgac gttgtatttt ctctcgtcac 1680 cataaatgca tcgacgatgt acgcatattt gccgttgcga atgttttccg ccgtcggtgt 1740 aataccgtta atcgctagca atcttatatt tttatcagca ttcatttgcg tcgcgtaata 1800 gcggaaggta tagcctattg cgttgtttgt attacggtat tcggcaacga ctttaatcat 1860 tccctccatc acgcttgcca cttccgtttc ctgcggcgag atcatgcgga cttttttcat 1920 gacctgtgat tgcatcactg tctggctgcc agagtcttcc gggcgctgcc aggtctggat 1980 ctcctgatcg ttaccgccaa cagtacgcca attggtaatt gcaccactga aaatgtcacg 2040 cacctgttgt tcagtcaggg aattaaccgg attatccgca ttgacgatga aaacaaatgc 2100 ttcacgggca aatggcgtgt atagcaaagt gacgcccgat tcctcagcgc gttttttctg 2160 cccgccggag ggttgcgcca caaaaataat atcggcatca cctttaacaa tccggttata 2220 tgcatcgggg gtacgagagt tctccagata ttcccaaacg tgaaaatcct ctggtattac 2280 acttaatgca taaaatgcag aagcataaat tgggtacgca gccgtggcgc catcgattcg 2340 cggccagttt tgcctaaact gaatttgcgg tttgccacgc agcggcgtca gtcgattatt 2400 gagtttatcg ggtcgccagg ccctgatatc aatattttcg cgtacaccga caccaggatt 2460 ttgctgctta tataaatggg cctgataccc ggcgacaata ccaagtaaga gaagtagaaa 2520 caggagtaag ttacggcaac gtagtccgga cgtgccggat aaaggatatc tggtcggcca 2580 ggcgtatccc agcgaaaaac tgatatgcgc cccaacggga ataatgacca tccaccagta 2640 ctcaccaccc actaatgaga ctaaaaaaac gcccaaccag ggaagcataa ggtttgccaa 2700 ccaaccagct cccatctggc gaaattgata atctgccaga tgtagcgtga ttatccagcc 2760 aaccagggtt aatagcgcgg gtaagagaaa aaagcattgc cgccagacgg ctatttctct 2820 gttttctggc gcgctatcac cggcccacac gc 2852 <210> 1548 <211> 331 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(543..1535) <400> 1548 Met Asn Lys Phe Thr Gly Val Leu Leu Leu Gly Thr Ala Leu Leu Ala 1 5 10 15 Gly Cys Val Asp Arg Glu Gly Tyr Tyr Asn Ser Val Arg Glu Glu Glu 20 25 30 Ser His Gly Leu Thr Ser Leu Arg Gly Gln Pro Ala Leu Arg Tyr Ser 35 40 45 Asp Asp Trp Ser Arg Trp Pro Arg Val Tyr Gly Ala Thr Ala Leu Tyr 50 55 60 Pro Leu Tyr Ala Ser Ala Tyr Tyr Lys Leu Val Pro Glu Pro Lys Asp 65 70 75 80 Lys Asp Arg Thr Ser Leu Ala Trp Gln Ala Tyr Gly Leu Gln Gln Thr 85 90 95 Arg Thr Ala Glu Ala Tyr Asp Ser Leu Ile Lys Gly Ser Ala Thr Val 100 105 110 Ile Phe Val Ala Gln Pro Ser Glu Gly Gln Lys Lys Arg Ala Glu Glu 115 120 125 Ala Gly Val Lys Leu Lys Tyr Thr Ala Phe Ala Arg Glu Ala Phe Val 130 135 140 Phe Ile Val Asp Ile Asn Asn Pro Val Asn Ser Leu Ser Glu His Gln 145 150 155 160 Val Lys Asp Ile Phe Ser Gly Lys Thr Ser Arg Trp Asn Lys Val Gly 165 170 175 Gly Ser Asp Glu His Ile Lys Val Trp Gln Arg Pro Glu Asp Ser Gly 180 185 190 Ser Gln Thr Ile Met Lys Gly Leu Val Met Gln Asp Thr Pro Met Leu 195 200 205 Pro Ala Lys Lys Ser Thr Val Ile Asp Leu Met Gly Gly Leu Ile Thr 210 215 220 Glu Val Ala Asp Tyr Gln Asn Thr Pro Ser Ser Ile Gly Tyr Thr Phe 225 230 235 240 His Tyr Tyr Val Thr Arg Met Asn Asp Asn Met Leu Lys Met Arg Lys 245 250 255 Gln Ile Lys Leu Leu Ala Ile Asn Gly Val Ala Pro Thr Glu Glu Asn 260 265 270 Ile Arg Asn Gly Thr Tyr Pro Tyr Ile Val Asp Ala Tyr Met Val Thr 275 280 285 Arg Glu Asn Pro Thr Pro Glu Thr Gln Lys Phe Val Asp Trp Phe Ile 290 295 300 Ser Gln Gln Gly Gln Gln Leu Val Glu Asp Val Gly Tyr Val Pro Leu 305 310 315 320 Tyr Glu Ala Ser Pro Glu Ser Ser Gly Gln * 325 330 <210> 1549 <211> 2807 <212> DNA <213> Escherichia coli O157:H7 <400> 1549 accatgtaag ggcaaaagag tatcacaggc ttttgcccat tattcaggta acacggtcag 60 acatgcatga catgtctgat tttattgttt taataaattt gctttatgat ctatctagtg 120 tatctaaaat ggcaatgaaa ttatttctcc ttgcaatttg aattattgtt aataacattg 180 gttgatattc ataaacaaat tctgggaaaa tctggaataa acatgctatt gcataaagag 240 tttgttcatc atctggtaaa ttattatgag atatgtgatt cagtattagc ttgattctgt 300 ccctgatttt attattttca ttgtctatag tgtatccgac tatctcccta agcaaaataa 360 agtgtgcagt cgtttcatta ccgtatatct ttagtagttc taataaacta tcaaaaatcg 420 ctcatttcag cttattgata gaaagattga ttgccagtct gtttagagcc gtacagcagc 480 aaactttcat aaccaggttg atcctgaatt tgcagtacga aaagttaaaa atgagcgatt 540 tctgtaagac tccccatttt gccaggctta tgattcgcag atcattcaag tgcaaaggag 600 cgatgtatgg attgttcaaa atgcaatggt tatgcgacga tgttattaaa tatggtgcag 660 ggttctgacc cggttaattt actggaatta catggtttcc ttgaacattt cgcatattat 720 gtttcatttg gcaaatttaa tgctggccac cagcgctata atgcatttaa aaaattcgtc 780 agtgagattt cggagatcag cgcaaatgat atcaatatga cgattaaaac cgggcaatcc 840 agacatgaaa atgtgatctc tataaatatg aatgatgcaa ttcctcgtga tgagaaaggg 900 atcaccgtta gaatagataa tattaatgga aagaaaaaca actctaattc atcagatgtt 960 tttattcctt atgtaaatac atttcccgac ctcaaaaata aaatactcag gatgaaaatt 1020 gaactgactg aaggtagtgg tttttctaaa agtctttctg acagtcagat tgagatgcat 1080 attctgagga ctgttaattc gctaaatgtt ggcgagaaat tgaatgatga taatcttgca 1140 gatcattcta tattcactaa cgaattctct gttattattc cgccatccta ttatgatgca 1200 acttctgcag taaacgctaa taatattgtg agagaaaaac tatttgaaag tgatagtaaa 1260 gttaaagata tcgtcgatga tatgtctaat catgacgtgg agagcgaaaa agatatattt 1320 gtaatcgggg ggatgataga aaaactgaat tctctggcag acgaatcttt caatgatagt 1380 actgataaca tacaaacagt aaaagatctg ttaacgcaat taactgatgg catggagctc 1440 ttcgcgctgc gggacatagt ggcattccca tcaaccataa tagcaaaatt aataaaatcc 1500 ccacttaata gcgatcatga acttgttatg cgcgcactgg atacgtatct gtgctacttc 1560 agaaataaaa atctgaataa caatgcggaa ataattaact ttttccatgc cctcttttta 1620 aagagaccag agttgatggt tgctgaaaat tatagattta ttcaatttat tgatttgctt 1680 tttgaaaacg gaaatgttga agagaaaaac ttagcatttg acctttatca caattatctt 1740 tcattatctg aaataaaaca attcgttact gaagaaatta aattgaattt caatgagcag 1800 caaggattgt tagataaaga taataaatgt tatatcctgt tatcatccga taactctggg 1860 cgagtaatgc gcttatcgca ccaggcgtta atctcaatgc ttgagccaga ggttaagaaa 1920 aagactatct ggaataatta ctctatttat ccatctttgc aggataccca tgaagttgtc 1980 agagatgatc cagaaacgat ttgtatgcgt gcatttcctt tatttgcaaa aggatgggaa 2040 tatgcgcaga aaaataagaa acatcaattg atcctcaatg ctcttggatt caaaggttat 2100 attcgtgata tatttatgtc agcaataatg cgaaaaacag attttgtgct cgaatgcaat 2160 aatcaaccga cagaacttaa ttcatcattt tcctctttga tgaacgattc agatcaatgg 2220 caacagcata ctctgaaaga taaacattac gctaatctat taacgatgct ggatctcaat 2280 gatgccagtg aaagtgataa gtctaaaata tttttctgcc tgtctgccgt atttgcaaat 2340 atttctcaca gtaatgtctt taacggtatt cctgatgcgt caaaaacttt aaaacgttat 2400 gcatttgctt tattggcgaa agctcattct ttagatgaaa gtatgataag caatcaaact 2460 tttaatacat acaaaacggt attgcttgat ttcaataatc tgtctaatga agaggccaac 2520 cagttgcgca taagttcgtt atatcgtgat atggtccgct atgcacaata tcgtttttct 2580 aaagttttat ccgagtggac gccagacgca tggctgtaaa gatcgcagca gaataatggc 2640 attgatggcc ctggctcagg ccagggtcgg caataccggt tcctgcgaag cgatgacggc 2700 ggcaattgta accacgaaat gcggtatcac ttgctgtttt ctgccctgaa gactggcgct 2760 cactgtgccg tcgaattttc aatcaaatat attgcgagag ggcgtgt 2807 <210> 1550 <211> 671 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(607..2619) <400> 1550 Met Asp Cys Ser Lys Cys Asn Gly Tyr Ala Thr Met Leu Leu Asn Met 1 5 10 15 Val Gln Gly Ser Asp Pro Val Asn Leu Leu Glu Leu His Gly Phe Leu 20 25 30 Glu His Phe Ala Tyr Tyr Val Ser Phe Gly Lys Phe Asn Ala Gly His 35 40 45 Gln Arg Tyr Asn Ala Phe Lys Lys Phe Val Ser Glu Ile Ser Glu Ile 50 55 60 Ser Ala Asn Asp Ile Asn Met Thr Ile Lys Thr Gly Gln Ser Arg His 65 70 75 80 Glu Asn Val Ile Ser Ile Asn Met Asn Asp Ala Ile Pro Arg Asp Glu 85 90 95 Lys Gly Ile Thr Val Arg Ile Asp Asn Ile Asn Gly Lys Lys Asn Asn 100 105 110 Ser Asn Ser Ser Asp Val Phe Ile Pro Tyr Val Asn Thr Phe Pro Asp 115 120 125 Leu Lys Asn Lys Ile Leu Arg Met Lys Ile Glu Leu Thr Glu Gly Ser 130 135 140 Gly Phe Ser Lys Ser Leu Ser Asp Ser Gln Ile Glu Met His Ile Leu 145 150 155 160 Arg Thr Val Asn Ser Leu Asn Val Gly Glu Lys Leu Asn Asp Asp Asn 165 170 175 Leu Ala Asp His Ser Ile Phe Thr Asn Glu Phe Ser Val Ile Ile Pro 180 185 190 Pro Ser Tyr Tyr Asp Ala Thr Ser Ala Val Asn Ala Asn Asn Ile Val 195 200 205 Arg Glu Lys Leu Phe Glu Ser Asp Ser Lys Val Lys Asp Ile Val Asp 210 215 220 Asp Met Ser Asn His Asp Val Glu Ser Glu Lys Asp Ile Phe Val Ile 225 230 235 240 Gly Gly Met Ile Glu Lys Leu Asn Ser Leu Ala Asp Glu Ser Phe Asn 245 250 255 Asp Ser Thr Asp Asn Ile Gln Thr Val Lys Asp Leu Leu Thr Gln Leu 260 265 270 Thr Asp Gly Met Glu Leu Phe Ala Leu Arg Asp Ile Val Ala Phe Pro 275 280 285 Ser Thr Ile Ile Ala Lys Leu Ile Lys Ser Pro Leu Asn Ser Asp His 290 295 300 Glu Leu Val Met Arg Ala Leu Asp Thr Tyr Leu Cys Tyr Phe Arg Asn 305 310 315 320 Lys Asn Leu Asn Asn Asn Ala Glu Ile Ile Asn Phe Phe His Ala Leu 325 330 335 Phe Leu Lys Arg Pro Glu Leu Met Val Ala Glu Asn Tyr Arg Phe Ile 340 345 350 Gln Phe Ile Asp Leu Leu Phe Glu Asn Gly Asn Val Glu Glu Lys Asn 355 360 365 Leu Ala Phe Asp Leu Tyr His Asn Tyr Leu Ser Leu Ser Glu Ile Lys 370 375 380 Gln Phe Val Thr Glu Glu Ile Lys Leu Asn Phe Asn Glu Gln Gln Gly 385 390 395 400 Leu Leu Asp Lys Asp Asn Lys Cys Tyr Ile Leu Leu Ser Ser Asp Asn 405 410 415 Ser Gly Arg Val Met Arg Leu Ser His Gln Ala Leu Ile Ser Met Leu 420 425 430 Glu Pro Glu Val Lys Lys Lys Thr Ile Trp Asn Asn Tyr Ser Ile Tyr 435 440 445 Pro Ser Leu Gln Asp Thr His Glu Val Val Arg Asp Asp Pro Glu Thr 450 455 460 Ile Cys Met Arg Ala Phe Pro Leu Phe Ala Lys Gly Trp Glu Tyr Ala 465 470 475 480 Gln Lys Asn Lys Lys His Gln Leu Ile Leu Asn Ala Leu Gly Phe Lys 485 490 495 Gly Tyr Ile Arg Asp Ile Phe Met Ser Ala Ile Met Arg Lys Thr Asp 500 505 510 Phe Val Leu Glu Cys Asn Asn Gln Pro Thr Glu Leu Asn Ser Ser Phe 515 520 525 Ser Ser Leu Met Asn Asp Ser Asp Gln Trp Gln Gln His Thr Leu Lys 530 535 540 Asp Lys His Tyr Ala Asn Leu Leu Thr Met Leu Asp Leu Asn Asp Ala 545 550 555 560 Ser Glu Ser Asp Lys Ser Lys Ile Phe Phe Cys Leu Ser Ala Val Phe 565 570 575 Ala Asn Ile Ser His Ser Asn Val Phe Asn Gly Ile Pro Asp Ala Ser 580 585 590 Lys Thr Leu Lys Arg Tyr Ala Phe Ala Leu Leu Ala Lys Ala His Ser 595 600 605 Leu Asp Glu Ser Met Ile Ser Asn Gln Thr Phe Asn Thr Tyr Lys Thr 610 615 620 Val Leu Leu Asp Phe Asn Asn Leu Ser Asn Glu Glu Ala Asn Gln Leu 625 630 635 640 Arg Ile Ser Ser Leu Tyr Arg Asp Met Val Arg Tyr Ala Gln Tyr Arg 645 650 655 Phe Ser Lys Val Leu Ser Glu Trp Thr Pro Asp Ala Trp Leu * 660 665 670 <210> 1551 <211> 2701 <212> DNA <213> Escherichia coli O157:H7 <400> 1551 cctccttctt aacccattta ttcactatta atcgcttttt attatggctg atagttttat 60 cttgccgaag cgtgcttttt tgttattgtc tttgtgaaat cttcttataa aacaaacata 120 taaatatttt atattgatga gttatttgta tttacaccat caataaaatc cgttaattag 180 cctgtttata agtgaataaa ggaatagccg atgatcgaac actatattcg agggtttgag 240 gaagaactgc gtgagatccg ccatcagatc cacgaaaacc cggagctggg attacaagaa 300 tttaaaacca gtgctttggt tgcggaaaag ctgcgtcagt ggggctatga agtagagcaa 360 ggactggcga cgacggggat agtggccacg ttaaaagtgg gcgacggaga gaaaagtatt 420 ggcctgcggg cggatatgga tgcgctgccg atttatgaaa atagtggcaa gccctgggcc 480 agtaaacatc ctggtttaat gcacgcctgc gggcatgacg ggcataccac catactgctg 540 ggggccgcgc gttattttgc cgaaacccgc cgttttaacg gcacgttacg tcttatcttc 600 cagcctgcgg aagagatgat taatggcggt gagatcatgg ttaaagaggg gctttttgat 660 catttcccct gcgatgtcat tttcggcatg cataacatgc ccggtctgcc ggtgggtaag 720 ttttatttcc agccaggggc actgatggcg tcaatggatc agttccatat tacagttcgt 780 ggttgtggcg gacacggtgc gatcccgcac aaagccatcg atccggtgct agttgccgca 840 catatcacca ccgcattaca aagcattgtg tcacgcaatg tcgatccgct ggaagcggcg 900 gtaattaccg tcggcagcat tgttgcgggt gaggcggcta acgtcattcc tgacagtgct 960 gagatgaaaa tcagcgtccg ctctcttagc cgcgataccc gacaacttct tctgacccgt 1020 attcctgctc tggcacaagc ccaggctgcc agctttggcg ctacggctga ggttacgcat 1080 gttaacggta caccagtatt agtaaatgac gaggagatgg cgcgcttcgc ctggcaggtg 1140 gcgtgtaaaa cgtttggtga agatcgggcc gagtttggca tcaagcccct gatgggcagt 1200 gaagatttct ctttcatgct ggaagcccaa cccaaaggcg gtttcctgtt attcggtaat 1260 ggcgatgtcg gggaaggttc ctgcatggtg cataacccgg gttacgactt caacgatgca 1320 agtctggtcc cggcaagcag ctactggggc gcactggtag aagcctggct gcaataaata 1380 aaacaacaca caacaacact ttttggcaag gaacatggaa tgacggcgat cgtaaatgaa 1440 accgtgagtg tgaagaaaaa gcccagcggc aggcgggtga tttttgcctc ggcgtttggc 1500 aatgcgctcg aattttttga ttttggcgtt tacaactttt ttgtggtcta tatcagcacg 1560 ctattttttc cgcccagtgc agataaaaac gtcgcgctac tgctggcgtt tgccactttc 1620 ggcgtgagct tttttatgcg cccgctcggc ggcattattg tgggggcctg ggccgatcgt 1680 ttcggacgca aacccgcgat ggtgttcacc attgcgctga tgagtcttgg tacactgatg 1740 atcggcatcg caccgacgta tgaaacggcg ggctattggg gaaccgcgac gctggtgcta 1800 gcgcgtctaa ttcagggcgt tgcggcagga ggcgaagtcg gtgcctcaat gtctttgttg 1860 gttgaatcag ctccggcaaa tcgtcgcggt ttttacagca gttggtcact ggcgactcaa 1920 ggcctggcaa caacttttgg aggtgttgtc gctttaggtt taagtgcatg gctgcccttt 1980 gcgaccggtt cagaaaccgt catggctgaa tggggctggc gtgtgccgtt ttttattggc 2040 gtgttattag cgcctgtcgg ctgttggttg cgtttgagtc tggaaaatga tgttcctgag 2100 ccagcacata ataagaaggc cgcagccagc gaaagcgcct tctccttact tatgcaacat 2160 aaagcgacta tcgctaacgg tatcttgctc gctattggta gtacagtcgc aacctatatc 2220 tccctctttt attacggtac atgggcggcg aagtatttag gaatgaacca aaactattct 2280 catgcagcga tgttactggc gggcgttatt acgtttgtgg gtgcgctgct ggtggggatg 2340 ttgtgcgatt cggtcgggcg taaaaagctg attttaatct cccgtgtgat ggtgctgatc 2400 tgtagctggc cgtcattctg gctgttggtg aattacccaa gcccaggcat gttgctgacg 2460 gtggttttcg tgatggtcag ctttaccacg cttggcggtg tgccagtgat gttgttgatc 2520 tctgaactgt tgccgaaacg gattcgggca ttgggttttg cgctggttta tagcattggt 2580 gtggcaatct ttggcggttt tgctcaatat ttcgctacgc aatccatcgt gttgctggat 2640 agtttgacgg ctccggcgtg gtatctgggt ggaggcacgt tgctgtcgat gttggcgttg 2700 t 2701 <210> 1552 <211> 389 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(211..1377) <400> 1552 Met Ile Glu His Tyr Ile Arg Gly Phe Glu Glu Glu Leu Arg Glu Ile 1 5 10 15 Arg His Gln Ile His Glu Asn Pro Glu Leu Gly Leu Gln Glu Phe Lys 20 25 30 Thr Ser Ala Leu Val Ala Glu Lys Leu Arg Gln Trp Gly Tyr Glu Val 35 40 45 Glu Gln Gly Leu Ala Thr Thr Gly Ile Val Ala Thr Leu Lys Val Gly 50 55 60 Asp Gly Glu Lys Ser Ile Gly Leu Arg Ala Asp Met Asp Ala Leu Pro 65 70 75 80 Ile Tyr Glu Asn Ser Gly Lys Pro Trp Ala Ser Lys His Pro Gly Leu 85 90 95 Met His Ala Cys Gly His Asp Gly His Thr Thr Ile Leu Leu Gly Ala 100 105 110 Ala Arg Tyr Phe Ala Glu Thr Arg Arg Phe Asn Gly Thr Leu Arg Leu 115 120 125 Ile Phe Gln Pro Ala Glu Glu Met Ile Asn Gly Gly Glu Ile Met Val 130 135 140 Lys Glu Gly Leu Phe Asp His Phe Pro Cys Asp Val Ile Phe Gly Met 145 150 155 160 His Asn Met Pro Gly Leu Pro Val Gly Lys Phe Tyr Phe Gln Pro Gly 165 170 175 Ala Leu Met Ala Ser Met Asp Gln Phe His Ile Thr Val Arg Gly Cys 180 185 190 Gly Gly His Gly Ala Ile Pro His Lys Ala Ile Asp Pro Val Leu Val 195 200 205 Ala Ala His Ile Thr Thr Ala Leu Gln Ser Ile Val Ser Arg Asn Val 210 215 220 Asp Pro Leu Glu Ala Ala Val Ile Thr Val Gly Ser Ile Val Ala Gly 225 230 235 240 Glu Ala Ala Asn Val Ile Pro Asp Ser Ala Glu Met Lys Ile Ser Val 245 250 255 Arg Ser Leu Ser Arg Asp Thr Arg Gln Leu Leu Leu Thr Arg Ile Pro 260 265 270 Ala Leu Ala Gln Ala Gln Ala Ala Ser Phe Gly Ala Thr Ala Glu Val 275 280 285 Thr His Val Asn Gly Thr Pro Val Leu Val Asn Asp Glu Glu Met Ala 290 295 300 Arg Phe Ala Trp Gln Val Ala Cys Lys Thr Phe Gly Glu Asp Arg Ala 305 310 315 320 Glu Phe Gly Ile Lys Pro Leu Met Gly Ser Glu Asp Phe Ser Phe Met 325 330 335 Leu Glu Ala Gln Pro Lys Gly Gly Phe Leu Leu Phe Gly Asn Gly Asp 340 345 350 Val Gly Glu Gly Ser Cys Met Val His Asn Pro Gly Tyr Asp Phe Asn 355 360 365 Asp Ala Ser Leu Val Pro Ala Ser Ser Tyr Trp Gly Ala Leu Val Glu 370 375 380 Ala Trp Leu Gln * 385 <210> 1553 <211> 2700 <212> DNA <213> Escherichia coli O157:H7 <400> 1553 tcatacaaag taattttaaa ttgccaggta tcgcaggaat aacctcaatc ttattatatt 60 caatatacgc ttctttcaaa tttttgggga accatctaat ttctttaata ttattctcac 120 tacaatcaaa aaccttagcg gtgtctggta gtgctggtat ttccgatagc ttattgtgac 180 aaataaaaat tttcttagcc tttggcggaa atgagtcaat atacgatatc aggttattat 240 ttacggagat cagggtaatt ccatcaggta cttgtggaaa ttctgtaagg ttattgaaat 300 cgagttctaa ttctttgcac gattcgggca cctgtattga atcaagttca ttataaacaa 360 ggctaagcat ttcaatccac tcaggaagag gcggcacaga acccaaagaa aggcttgata 420 agttaagttc attactgtga agcttaacac atttaaacat tctcaccaat gctctatcca 480 cattttcttt caagtcattc gatgcgcctt ctttgactga actagcccag tcactgaaac 540 ctttgcaaag cctggcatct gtaattttgg ttaacttgtc cagcaactct gcaatattgg 600 tcgatataaa ctctaattta tgccgaatgg gtaaagtccc ctccccctga cttttttcta 660 tcgtgataga tcccgtctta tcataagccc cataattttc aaacaataga gtataattac 720 cccacctgaa acattgctct ctcaataact taaattcaga cagcatattc agtaagttgc 780 tgtcttcact aactggtgta aacttatcat ttccaagaca actgactaac tcacttgata 840 attcatttat gattgcatca tcagatacta actcgtgttg ttttatcgta gactcagtat 900 tcgatgtgat tttatttaat tgaaccgact gagtttttaa cgacagatca tttaatggaa 960 acatttacac tcctgtttaa taaattatat tgcccagggc gcattctaaa acacaataaa 1020 attgccacta tcaaaaatcg ctcattttta taacgcagta tattaataaa aataagaacg 1080 aagattaagt tatccagagg ttactgttgc gtctgtggtc gtaacaacat ccgacgtggt 1140 gatgtgtcaa atgagacatt ctgatgatca gagggtttat cgcgtatacg gatcgtgggt 1200 ggcagaaaac tttcagaatc aggtttccat tttaaaccag aaattgagtg agtttgcccc 1260 atccataacc ccacgcggtg agatcggatg tcattaaaca agccaggtca acaggtcagt 1320 atgggaaggc gaacaactcg caggaatggg tgcgctaaag ttgctggatg ataaacatgg 1380 cgaactgaaa tcaatgcgta ccgcgccaaa ttatttacgt cggggtgtcg ccagtctgat 1440 tttacgccac attttgcagg tcgcccatga cagatgcctt catcgcctga gcttagaaac 1500 gggtacacag gctggattta cggcctgcca tcaactttat ttgaagcatg gtttcgttga 1560 ttgcgaaccg tttgctgatt atcaatttga tccacacagt cgatttttgt cattgacgct 1620 atgcgaagat aatgaattgc catgagccag acgcagcgca ttcttgcatt cgacgtgctg 1680 cgcctttatt tatcaccagc aggaaacgcc ttgtccatag acgctccttc cacatgcgtc 1740 acaagaaacc tctattccag tgacacaatt acgcctaatt aattacataa aatatttaat 1800 tatgagttcc tcaccatcta ttacatgctt tttaaccata tcggaatatt tatcataatc 1860 ggctggattc gtaacaatat attttcgctg cgatatttca tagcagatcc ctgtcagagt 1920 ccatggcatt aaaaatgcct ctttaatagg attacattcc ataaaaagta tttttaaatt 1980 gccaggtatc gcaggaacaa cctcaatatt attatatcca atacgcgctt ctttcagatt 2040 tttggggaag tatcgaattt cttgtatctt attatagcca caatcaaaaa ccttagcggt 2100 gtctggtatt gctggtgttt ccgatagctt attgtgacta ataaaaattt tcttagcctt 2160 tggcggaaat gagtcaatat gcgatatcag gttattattt acggagatca gggtaattcc 2220 atcaggtact tgtggaaatt ctgtaaggtt attgaaatcg agttctaatt ctttgcatga 2280 ttcgggaacc tgtattgaat caagttcatt ataaacaagg ctaagcattt caatccaatc 2340 tggaagaggc ggcacagaac ccaaaaatag gtatgataag tcaagttcat tactgtgaag 2400 cttaacacat ttaaacattc tcaccaacgc tctatctaca ttttctttga ggtcattcga 2460 tccgccttct ttgactgaac tagcccagtc actgaagcct ttgcaaagtc tggcatctgt 2520 aattttcgtt aacttgtcca gcaactctgc aatattagtc gatataaact ctaatttatg 2580 ccgaatgggt aaagtcccct ccccctgatt tttttctatc gtgatagacc ccgtcttatc 2640 ataagactca taattttcaa acaatagagt ataattaccc cacctgaaac attgctctct 2700 <210> 1554 <211> 100 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1346..1645) <400> 1554 Met Gly Ala Leu Lys Leu Leu Asp Asp Lys His Gly Glu Leu Lys Ser 1 5 10 15 Met Arg Thr Ala Pro Asn Tyr Leu Arg Arg Gly Val Ala Ser Leu Ile 20 25 30 Leu Arg His Ile Leu Gln Val Ala His Asp Arg Cys Leu His Arg Leu 35 40 45 Ser Leu Glu Thr Gly Thr Gln Ala Gly Phe Thr Ala Cys His Gln Leu 50 55 60 Tyr Leu Lys His Gly Phe Val Asp Cys Glu Pro Phe Ala Asp Tyr Gln 65 70 75 80 Phe Asp Pro His Ser Arg Phe Leu Ser Leu Thr Leu Cys Glu Asp Asn 85 90 95 Glu Leu Pro * <210> 1555 <211> 2689 <212> DNA <213> Escherichia coli O157:H7 <400> 1555 tgagtgccgg ataaagctat ttttttatcc ggcttatttc taaaaattgt cttttttaaa 60 gttatgcgga ttgaaaactt gctctatttt attttcttgt gttaattgat actcagtaaa 120 atcgttaata ccaatatgag tgttacgata agggtattca ttaataacca ttaagtaatt 180 tttcgtgatg caattatcat tgctcttaat tgtcgggaaa cagtagagat cttcatacgg 240 cccttcgata tattttttat agtcagtgaa gccattaccg atatcaatga cataccaggt 300 atgccaacta ccttctggta ggggatgttg atttttaatt tcattctgat gcttcagata 360 ccaatttatt ttatcgctgt cagtccatgg cagatgatca acgaccagaa agactgaatt 420 gccagcatca gagtatgtat acaaaatctg tacaggacgc aatgtccata aattatagat 480 gcagcataga agaaataaac ataatataat tttttggagt ttgcttttca tagataattt 540 tcgattcttt cgatagtgtt aaaattggtg aaaaaaggtt tgaaagcaaa gtctttatgc 600 cgttgtaaaa agaaccatat gcgaaaaaat ctatatttgc tgtaagtctt gtttttgata 660 tcagttacat caagaccgaa gtggtcctgt gctacaaaat gaattgttgc actccatcct 720 atagcgtatt tttgaaaact taaaagagat attttttgag ctgaaatatc atgaacactg 780 attcctaagc cattaaaact gtcctcgaag tcattaaatt tatttagtct tgatgaaagt 840 aatttggttt taatgctttg caggataaga ggttggtatc ctgtcgaggg agttgaatta 900 atgccatttt cgatacattc tttgattatt cgtattggac tattataacc atatttattt 960 attttttcat gaaaagataa atttaattgt tggctatgaa aattgctgcc atttccatat 1020 ctaaaatgtt caatcagatc ttcgataagt gttttatatt gtccaaaaaa ggaaaacatt 1080 tttgctagtt ctttcatttc tgcaaataaa atatcagtgc attcacgttg tgatattttt 1140 gttccggaac ttgaggcact aaaagcaaca ttaatagaac ctgggccagg gaaatggtat 1200 ttaataagtc tgtaaggatc aacttttgct gagatatcgc ttaggccgag tgagagaaaa 1260 tcttgttcta ccatatcacc atattgcata tcatcagcag aataattatc aaataaacta 1320 atagtttcga aaagtgtaca gggaatatta attgatggaa gtaatgtgtt attcatttac 1380 attttccttg gttatattta agctcaatat caatttgaga acaaatgcta gggtaaaaaa 1440 atatttaaaa aagaagtaca cttcacattt tttcattaca tctctgaaga gaacgtcgtt 1500 aatgattggt cttgctcatt gttaataaca aaatattgaa tttaccgatt aggaaacttt 1560 ttcctacgcc gattgcctcc agctatggca tgaactttga gtttatgcca gaactgaagt 1620 ggagtttcgg ctacccaggc gcgattatct ttatgatcct cgcgggcctg gcaccgtatc 1680 tgtactttaa gcgcaagaac tggctgtaac tatacgatgt cgctgtgagt aagttagtgt 1740 gctgacagcg acattttagc agagggaatc gcagataaca taattgttgt gaataatatc 1800 catgccacgt tgagttggac gcttaatgac tcacatctca ccccttcaat tgctgcagag 1860 ataatagaaa aaagtgtcaa acccaatgaa atcaatacaa agtagattgc cttacatcca 1920 gtatctctta ttctttttgc tccaatattg atatttacat aggtattatt aataaccaga 1980 ataaaactca aagccaggtt gatatcattc aaagttatta atattgacca tgatgttaat 2040 gtatagatta tgaactgaaa gcgtgataaa cgctcaagct tggatgggta gaatatattt 2100 ctgatggatg atttgaacat tttttacatt gttttatata tataattgtt ttgaatatat 2160 attacctgaa ttatgtggtt tgcatatata tatgcaatat agcagtcttt gcattgataa 2220 ctatacagta gtaatttaga gtgtgtaagt ttttattgat ggggtatatt ttaattaaat 2280 ataattggaa tgtattttta ttctataaac aatatcttgg gtgaatggat tctatatggg 2340 aaatggtaac ttttggcagt tgttcttggg taaagaacct tacagcaaaa aatctgattt 2400 tgttaaggca tggttattgt ggtgggctat taccatcctt gttctattta ttttaagcct 2460 gactacgaca ttaaatttaa gaagtatagg tatagggtta agttttgggt tttgtcaaat 2520 ccttggtaga tatacgatgt ctctaggatg gagtaagtac tggggagttt tggggggatt 2580 tcctgtaaca aatattgttc tttttcttat cttaattttt ttcaaaaaaa gataaataag 2640 tcagtgggta ggctctttaa acggcctacc catgttaatt cttaacttt 2689 <210> 1556 <211> 283 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(528..1376) <400> 1556 Met Asn Asn Thr Leu Leu Pro Ser Ile Asn Ile Pro Cys Thr Leu Phe 1 5 10 15 Glu Thr Ile Ser Leu Phe Asp Asn Tyr Ser Ala Asp Asp Met Gln Tyr 20 25 30 Gly Asp Met Val Glu Gln Asp Phe Leu Ser Leu Gly Leu Ser Asp Ile 35 40 45 Ser Ala Lys Val Asp Pro Tyr Arg Leu Ile Lys Tyr His Phe Pro Gly 50 55 60 Pro Gly Ser Ile Asn Val Ala Phe Ser Ala Ser Ser Ser Gly Thr Lys 65 70 75 80 Ile Ser Gln Arg Glu Cys Thr Asp Ile Leu Phe Ala Glu Met Lys Glu 85 90 95 Leu Ala Lys Met Phe Ser Phe Phe Gly Gln Tyr Lys Thr Leu Ile Glu 100 105 110 Asp Leu Ile Glu His Phe Arg Tyr Gly Asn Gly Ser Asn Phe His Ser 115 120 125 Gln Gln Leu Asn Leu Ser Phe His Glu Lys Ile Asn Lys Tyr Gly Tyr 130 135 140 Asn Ser Pro Ile Arg Ile Ile Lys Glu Cys Ile Glu Asn Gly Ile Asn 145 150 155 160 Ser Thr Pro Ser Thr Gly Tyr Gln Pro Leu Ile Leu Gln Ser Ile Lys 165 170 175 Thr Lys Leu Leu Ser Ser Arg Leu Asn Lys Phe Asn Asp Phe Glu Asp 180 185 190 Ser Phe Asn Gly Leu Gly Ile Ser Val His Asp Ile Ser Ala Gln Lys 195 200 205 Ile Ser Leu Leu Ser Phe Gln Lys Tyr Ala Ile Gly Trp Ser Ala Thr 210 215 220 Ile His Phe Val Ala Gln Asp His Phe Gly Leu Asp Val Thr Asp Ile 225 230 235 240 Lys Asn Lys Thr Tyr Ser Lys Tyr Arg Phe Phe Arg Ile Trp Phe Phe 245 250 255 Leu Gln Arg His Lys Asp Phe Ala Phe Lys Pro Phe Phe Thr Asn Phe 260 265 270 Asn Thr Ile Glu Arg Ile Glu Asn Tyr Leu * 275 280 <210> 1557 <211> 100 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2336..2635) <400> 1557 Met Gly Asn Gly Asn Phe Trp Gln Leu Phe Leu Gly Lys Glu Pro Tyr 1 5 10 15 Ser Lys Lys Ser Asp Phe Val Lys Ala Trp Leu Leu Trp Trp Ala Ile 20 25 30 Thr Ile Leu Val Leu Phe Ile Leu Ser Leu Thr Thr Thr Leu Asn Leu 35 40 45 Arg Ser Ile Gly Ile Gly Leu Ser Phe Gly Phe Cys Gln Ile Leu Gly 50 55 60 Arg Tyr Thr Met Ser Leu Gly Trp Ser Lys Tyr Trp Gly Val Leu Gly 65 70 75 80 Gly Phe Pro Val Thr Asn Ile Val Leu Phe Leu Ile Leu Ile Phe Phe 85 90 95 Lys Lys Arg * <210> 1558 <211> 2659 <212> DNA <213> Escherichia coli O157:H7 <400> 1558 aaatcagtga atccccgttt gcaccgaaag aatatgctgc aaactttcta ccataatgcg 60 ccccgactga aataagcctt cctggatttc gttgttaaca ttcacagcgt gaaccaggga 120 ggctaataat actacttgca agaaggcaaa aataaacgca ccgataatca taatatgcgt 180 caggggtatt ttcctttgct ccttcatttt aaataaccca caaactggcc ttctttcatt 240 aaggcgactt ttcctgtgtg atgataaaca atgacgttat atagacctga ctgataaaca 300 gtggcatctt tattgtcttc atcaattgca cataatgaat cattgagata agcaaagttt 360 ttactgctca ttctaaaggt catgccaaat cctttataaa tggctttctt tgccgcctgg 420 gcgtgttgtg cggcttctgc atttttaaat gcctgtgcct cggatgcact taaaatagcc 480 gcctgacgct gctgttctgc gaggtaacag gtgtcatgac tgacgccctg cgcctggcaa 540 tctgcgatgc gggaagtggg tgaactacag ccagccagta atataaccgc cagcagggaa 600 aacgatttaa tggagctatt catcattgtt aaccttaaat aatgtacaaa ttaatgaaga 660 ggtgaacccg gcaagcttcc ttgctcttat ttatattgag gattgaaata ttagaacgaa 720 tatcccacgc cgacacctgc gccgaaatca gattgtgtat ccgcagaaat accggcttta 780 agtaccgtat gcgttccggc attaaatgat gttccgacag acaccgcaga ttcaccgttg 840 aaggttcccg ctcccgctga caccatcatc acgtcaccgg ttttaacctg tggttgtgag 900 gcgatagcga tggcagatgc agttcccgca ttggcttctt tacgattgtc atcaacttcg 960 ttttttagcg aactgaaatg gttattgagc gtgttaattt gctggctgtt atctgcaacc 1020 cgtttttggg tgttggttaa ctgttggtgc gtttgggtta cgtcttgtga caggctgtca 1080 atttgttcat gtgcctgggc agactcctgc gccagacttt gcatttgttt atcgtattga 1140 gtcctttcat tttgctgttg tactgccaca tcggttgtca gcgcattcat tttctgccct 1200 tgttcagtgg cggtgcgctg attagcctca ttttgagccg ccagtctggc attaatcatt 1260 tcctgataat gcgcggtatt ttgcgtatct ccagtcgcgg cgagcgtttt ttgtgtggct 1320 acgatctgcg cctgttgctc tgtaatttgc gtttgctggg cgtcagttac cgcagactgt 1380 cgggcgttga tcatgctctg ataacgggca gttgtctgta catcacctgt agcggcaacg 1440 gttttttgtc ctgcgtcagg atctgtctgg acagtgggag tctgagtggt atcaggtgtt 1500 tcagaaggga tgtagtgatg ttcagtcaaa taggtatacg cagcggggct gttgtctgtg 1560 cgttctaaaa agcgggtaat cttctgctca atctccgatt gcgacatgcc agagttaatg 1620 gctgaaagct ctgttgccgc cgcttcaatg gtatcaccag ctaaaacaac agggctggat 1680 gttgctgaaa ttatgagtgc cagtaaagct acgtttacag ttttcattca ttttctcttg 1740 ttcaaaataa gtcgtattaa tgtttctata agaaacaaat aatattgttt taagaaataa 1800 actgcgttgc aatttaatcg aaatctacgc cgccatttgt gtgatgtaaa gcgcattttt 1860 gtctgttgta agcgtaaaca ccatcaataa gaaacaaaaa tggtttctta tataaataaa 1920 aaaggaaatc atttcgtgct ctttcaatgt aaaaaagagt aaagacttgt tttgataagc 1980 gaaataaatt ctgtttctgg actaaacgtg aagcggttcc tgatgtgtgc taaaatgcgt 2040 ttctttgata aatctcaatt tttaagaggt ttacgccagg caggaaaatt taaatgaatg 2100 aatttgagaa gatttttaat gaaatgaatc tggaccgggc attgctaccg atcctttttc 2160 gttcgaaccg gtcgacagtg tggaagtatt taagcggcga tagtacggct cctgcctctg 2220 ccatgtcgct gattatgctg ttgcagttga tacagaaacg aaaccccgat ctgttagccg 2280 aatggttaac gctttctgat ttcaccattc cgccagaagt ttacctggac cagcctgatt 2340 actggaaagg gtgggtgtat acgcaacaca aggtcaataa aaacgtcctg gaatatctaa 2400 aaaaacacta tccggatgaa gaccaaaaaa gtatgagtaa aggccgggaa gagtaaattg 2460 ccaatgccag ttaacattta acatggcgga ggcggcctac ggttttggcg tgatatgacg 2520 cgcccgcgtc gcatcaggcg tcggtgcacg actgccggat gcggcgtaaa cgccttatcc 2580 ggcctacgat tcgggcgcag acttccgggc atgataagac gcgtcagcgt cgcatcaggc 2640 gatgaccgca cggatgatc 2659 <210> 1559 <211> 141 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(204..626) <400> 1559 Met Met Asn Ser Ser Ile Lys Ser Phe Ser Leu Leu Ala Val Ile Leu 1 5 10 15 Leu Ala Gly Cys Ser Ser Pro Thr Ser Arg Ile Ala Asp Cys Gln Ala 20 25 30 Gln Gly Val Ser His Asp Thr Cys Tyr Leu Ala Glu Gln Gln Arg Gln 35 40 45 Ala Ala Ile Leu Ser Ala Ser Glu Ala Gln Ala Phe Lys Asn Ala Glu 50 55 60 Ala Ala Gln His Ala Gln Ala Ala Lys Lys Ala Ile Tyr Lys Gly Phe 65 70 75 80 Gly Met Thr Phe Arg Met Ser Ser Lys Asn Phe Ala Tyr Leu Asn Asp 85 90 95 Ser Leu Cys Ala Ile Asp Glu Asp Asn Lys Asp Ala Thr Val Tyr Gln 100 105 110 Ser Gly Leu Tyr Asn Val Ile Val Tyr His His Thr Gly Lys Val Ala 115 120 125 Leu Met Lys Glu Gly Gln Phe Val Gly Tyr Leu Lys * 130 135 140 <210> 1560 <211> 56 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(635..802) <400> 1560 Met Pro Glu Arg Ile Arg Tyr Leu Lys Pro Val Phe Leu Arg Ile His 1 5 10 15 Asn Leu Ile Ser Ala Gln Val Ser Ala Trp Asp Ile Arg Ser Asn Ile 20 25 30 Ser Ile Leu Asn Ile Asn Lys Ser Lys Glu Ala Cys Arg Val His Leu 35 40 45 Phe Ile Asn Leu Tyr Ile Ile * 50 55 <210> 1561 <211> 339 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(711..1727) <400> 1561 Met Lys Thr Val Asn Val Ala Leu Leu Ala Leu Ile Ile Ser Ala Thr 1 5 10 15 Ser Ser Pro Val Val Leu Ala Gly Asp Thr Ile Glu Ala Ala Ala Thr 20 25 30 Glu Leu Ser Ala Ile Asn Ser Gly Met Ser Gln Ser Glu Ile Glu Gln 35 40 45 Lys Ile Thr Arg Phe Leu Glu Arg Thr Asp Asn Ser Pro Ala Ala Tyr 50 55 60 Thr Tyr Leu Thr Glu His His Tyr Ile Pro Ser Glu Thr Pro Asp Thr 65 70 75 80 Thr Gln Thr Pro Thr Val Gln Thr Asp Pro Asp Ala Gly Gln Lys Thr 85 90 95 Val Ala Ala Thr Gly Asp Val Gln Thr Thr Ala Arg Tyr Gln Ser Met 100 105 110 Ile Asn Ala Arg Gln Ser Ala Val Thr Asp Ala Gln Gln Thr Gln Ile 115 120 125 Thr Glu Gln Gln Ala Gln Ile Val Ala Thr Gln Lys Thr Leu Ala Ala 130 135 140 Thr Gly Asp Thr Gln Asn Thr Ala His Tyr Gln Glu Met Ile Asn Ala 145 150 155 160 Arg Leu Ala Ala Gln Asn Glu Ala Asn Gln Arg Thr Ala Thr Glu Gln 165 170 175 Gly Gln Lys Met Asn Ala Leu Thr Thr Asp Val Ala Val Gln Gln Gln 180 185 190 Asn Glu Arg Thr Gln Tyr Asp Lys Gln Met Gln Ser Leu Ala Gln Glu 195 200 205 Ser Ala Gln Ala His Glu Gln Ile Asp Ser Leu Ser Gln Asp Val Thr 210 215 220 Gln Thr His Gln Gln Leu Thr Asn Thr Gln Lys Arg Val Ala Asp Asn 225 230 235 240 Ser Gln Gln Ile Asn Thr Leu Asn Asn His Phe Ser Ser Leu Lys Asn 245 250 255 Glu Val Asp Asp Asn Arg Lys Glu Ala Asn Ala Gly Thr Ala Ser Ala 260 265 270 Ile Ala Ile Ala Ser Gln Pro Gln Val Lys Thr Gly Asp Val Met Met 275 280 285 Val Ser Ala Gly Ala Gly Thr Phe Asn Gly Glu Ser Ala Val Ser Val 290 295 300 Gly Thr Ser Phe Asn Ala Gly Thr His Thr Val Leu Lys Ala Gly Ile 305 310 315 320 Ser Ala Asp Thr Gln Ser Asp Phe Gly Ala Gly Val Gly Val Gly Tyr 325 330 335 Ser Phe * <210> 1562 <211> 121 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(2094..2456) <400> 1562 Met Asn Glu Phe Glu Lys Ile Phe Asn Glu Met Asn Leu Asp Arg Ala 1 5 10 15 Leu Leu Pro Ile Leu Phe Arg Ser Asn Arg Ser Thr Val Trp Lys Tyr 20 25 30 Leu Ser Gly Asp Ser Thr Ala Pro Ala Ser Ala Met Ser Leu Ile Met 35 40 45 Leu Leu Gln Leu Ile Gln Lys Arg Asn Pro Asp Leu Leu Ala Glu Trp 50 55 60 Leu Thr Leu Ser Asp Phe Thr Ile Pro Pro Glu Val Tyr Leu Asp Gln 65 70 75 80 Pro Asp Tyr Trp Lys Gly Trp Val Tyr Thr Gln His Lys Val Asn Lys 85 90 95 Asn Val Leu Glu Tyr Leu Lys Lys His Tyr Pro Asp Glu Asp Gln Lys 100 105 110 Ser Met Ser Lys Gly Arg Glu Glu * 115 120 <210> 1563 <211> 2627 <212> DNA <213> Escherichia coli O157:H7 <400> 1563 gtcgtctaaa ttgatataaa gggcactgtt ccgttctggg ggaaactaac tatcagaacg 60 gaacagcgct tgttttttta tgagcatcct gcaccaaaac tgcctttact actggctgga 120 gcgactttca acatcttgca gtcctgtctt tacagagaac gatattgctt tagccgatta 180 agctcctctt gcggaaagtt aaattcgtct attgctttcc agaatagttc tttaaataca 240 ggattgccat ttgccttgct tattacatat ttgccttcat tattcttcgc ttccagttgc 300 atcatcacat ctttaagata attttcattt tcaccaacca caattttgaa tattttcagc 360 cagagaccca tatatatcat ccgctttctc taccgcaaga gagaatgact tcccatcaaa 420 gtcacgggta aactgctcca aaatctcatc gaaagtgaac ccgtgttgca acgccaggcg 480 aatcgccgca ttcagatata catcaatgac ctgcttactc attgtcttat agctggcaac 540 atacaaagag caaactgcat tatttctgct cagcgacagg agttctctca ctacatcttt 600 atcattttca taatggctgg ctatcacttc agctgtctcc atccaggcag caacaatctt 660 cgtatgccct ttcactatcg cagaatataa gcctgatgcc ttcgtccatt tgtctgatgc 720 tcccgccact ttttctcttg ctgccatcag tttcaatata tcttctttat ttaattcatt 780 tttaaacatt ttggctttta tattggctag caatatatta acaacattat aatcattggt 840 tctaatagcg ctatttaaat catcaattga gtctatttcc tttcctatac gaagaagtat 900 ttcattttta tttaccccaa attctttctc aaagtcatct atcgccaaca accatgcttt 960 gacaatttta ttttgattat ttttcaaagc cctgggaatc cagctcactc cgagattatc 1020 tttcgcaagg agtagagttt ccaggtcctc ttggctaaaa ttatattttc tggtcaactc 1080 ttttaaattt gttatgtaat cattaaactt atcaatagta ttgtgataca ataatacaca 1140 taacccatat attccttcag gtgatttcgc agcaagaata tcaagagcct ttgatgctgt 1200 catttcttga gagtttttta atttatcgaa aaaaagaaca atgtttttat atatccccat 1260 tctcattaat agaaataatg ctggtggtga taatggaggt tgcaactcat tttcaatacc 1320 acttaataaa tgggcttgtt cccgagggag ataaggggtt attcctacac actcggagca 1380 aatatctgtt attacccatt tttgttttgc ctgttgaata tttataaacg attgcaatga 1440 cccaaaagaa tcacagttgt ttgctttata gcgtactgca gtattggttg cattaggatc 1500 ataaaaggat acaacatatt ctgtttcacc agcaggcgtt tttttgatcc tcaagcggac 1560 ggccatagcg tgtgtttgag attgaacgat tgccgtcata tgcgttaact tctctttttc 1620 cattctgtga aaaaagacag ataatgcctc cccaaactta tcactggcaa cgacgcatgt 1680 accgggtggt ggattttttt gtagattgtt aaattgctgc tcaagctcga aaggaatatg 1740 tttttgtata tcttccggag atgaatagta agcctttaat ggaactttcc ctgtatgctc 1800 attcattgaa tctatacagt attgcagagc aaaatgtcta cattctatta aactttttgg 1860 ttttccagta aaatgcaaca ggcaattata atctacaata tcatatttgc tattagcttt 1920 tatctgctct tttgtaaaac tctcatcatc agggtacgta tgaaggcaag taaaaatatc 1980 atccaggaat tttataagca ctggagatac ggaaatatgt actatattga ttgcgtctgc 2040 atcgcttacg gttaaaatca taccttcagg ttgttgctta gatctggaga caagaattga 2100 atatgcacca tcgctataga aacctaactc aacttcagaa caatgattaa caaaatgatt 2160 taacggcccc tctttttcaa gtgaataaac tgaaggactt ttaagatacg caactatatc 2220 gtcaacgaat aattgagatt tatttttttc tccatccaaa tcaggcacga aagaaggaga 2280 ttgtatacat actctgctaa cagttacgtt atcaaccatt ttctttcccc tcatccatat 2340 gaaagttgta gtaataataa ggttactatt taaaaatcaa ctatcaaatt tcgctcattt 2400 atagagttat ttgtcttttt acgtcatttc cccatcaggt catcaacctg gtaatgaggt 2460 gggtaaaccg cgacatcaac gaggggaaca gctccttgta atggtatccc tataatcaat 2520 atcatcatct tcaacaataa ttataaaaat taaaaaaatt atccattcac gtatttttgt 2580 taatattctt tatgtgtcag ttctcataaa cacagccaat aactaaa 2627 <210> 1564 <211> 77 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(150..380) <400> 1564 Met Ile Tyr Met Gly Leu Trp Leu Lys Ile Phe Lys Ile Val Val Gly 1 5 10 15 Glu Asn Glu Asn Tyr Leu Lys Asp Val Met Met Gln Leu Glu Ala Lys 20 25 30 Asn Asn Glu Gly Lys Tyr Val Ile Ser Lys Ala Asn Gly Asn Pro Val 35 40 45 Phe Lys Glu Leu Phe Trp Lys Ala Ile Asp Glu Phe Asn Phe Pro Gln 50 55 60 Glu Glu Leu Asn Arg Leu Lys Gln Tyr Arg Ser Leu * 65 70 75 <210> 1565 <211> 663 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(331..2319) <400> 1565 Met Val Asp Asn Val Thr Val Ser Arg Val Cys Ile Gln Ser Pro Ser 1 5 10 15 Phe Val Pro Asp Leu Asp Gly Glu Lys Asn Lys Ser Gln Leu Phe Val 20 25 30 Asp Asp Ile Val Ala Tyr Leu Lys Ser Pro Ser Val Tyr Ser Leu Glu 35 40 45 Lys Glu Gly Pro Leu Asn His Phe Val Asn His Cys Ser Glu Val Glu 50 55 60 Leu Gly Phe Tyr Ser Asp Gly Ala Tyr Ser Ile Leu Val Ser Arg Ser 65 70 75 80 Lys Gln Gln Pro Glu Gly Met Ile Leu Thr Val Ser Asp Ala Asp Ala 85 90 95 Ile Asn Ile Val His Ile Ser Val Ser Pro Val Leu Ile Lys Phe Leu 100 105 110 Asp Asp Ile Phe Thr Cys Leu His Thr Tyr Pro Asp Asp Glu Ser Phe 115 120 125 Thr Lys Glu Gln Ile Lys Ala Asn Ser Lys Tyr Asp Ile Val Asp Tyr 130 135 140 Asn Cys Leu Leu His Phe Thr Gly Lys Pro Lys Ser Leu Ile Glu Cys 145 150 155 160 Arg His Phe Ala Leu Gln Tyr Cys Ile Asp Ser Met Asn Glu His Thr 165 170 175 Gly Lys Val Pro Leu Lys Ala Tyr Tyr Ser Ser Pro Glu Asp Ile Gln 180 185 190 Lys His Ile Pro Phe Glu Leu Glu Gln Gln Phe Asn Asn Leu Gln Lys 195 200 205 Asn Pro Pro Pro Gly Thr Cys Val Val Ala Ser Asp Lys Phe Gly Glu 210 215 220 Ala Leu Ser Val Phe Phe His Arg Met Glu Lys Glu Lys Leu Thr His 225 230 235 240 Met Thr Ala Ile Val Gln Ser Gln Thr His Ala Met Ala Val Arg Leu 245 250 255 Arg Ile Lys Lys Thr Pro Ala Gly Glu Thr Glu Tyr Val Val Ser Phe 260 265 270 Tyr Asp Pro Asn Ala Thr Asn Thr Ala Val Arg Tyr Lys Ala Asn Asn 275 280 285 Cys Asp Ser Phe Gly Ser Leu Gln Ser Phe Ile Asn Ile Gln Gln Ala 290 295 300 Lys Gln Lys Trp Val Ile Thr Asp Ile Cys Ser Glu Cys Val Gly Ile 305 310 315 320 Thr Pro Tyr Leu Pro Arg Glu Gln Ala His Leu Leu Ser Gly Ile Glu 325 330 335 Asn Glu Leu Gln Pro Pro Leu Ser Pro Pro Ala Leu Phe Leu Leu Met 340 345 350 Arg Met Gly Ile Tyr Lys Asn Ile Val Leu Phe Phe Asp Lys Leu Lys 355 360 365 Asn Ser Gln Glu Met Thr Ala Ser Lys Ala Leu Asp Ile Leu Ala Ala 370 375 380 Lys Ser Pro Glu Gly Ile Tyr Gly Leu Cys Val Leu Leu Tyr His Asn 385 390 395 400 Thr Ile Asp Lys Phe Asn Asp Tyr Ile Thr Asn Leu Lys Glu Leu Thr 405 410 415 Arg Lys Tyr Asn Phe Ser Gln Glu Asp Leu Glu Thr Leu Leu Leu Ala 420 425 430 Lys Asp Asn Leu Gly Val Ser Trp Ile Pro Arg Ala Leu Lys Asn Asn 435 440 445 Gln Asn Lys Ile Val Lys Ala Trp Leu Leu Ala Ile Asp Asp Phe Glu 450 455 460 Lys Glu Phe Gly Val Asn Lys Asn Glu Ile Leu Leu Arg Ile Gly Lys 465 470 475 480 Glu Ile Asp Ser Ile Asp Asp Leu Asn Ser Ala Ile Arg Thr Asn Asp 485 490 495 Tyr Asn Val Val Asn Ile Leu Leu Ala Asn Ile Lys Ala Lys Met Phe 500 505 510 Lys Asn Glu Leu Asn Lys Glu Asp Ile Leu Lys Leu Met Ala Ala Arg 515 520 525 Glu Lys Val Ala Gly Ala Ser Asp Lys Trp Thr Lys Ala Ser Gly Leu 530 535 540 Tyr Ser Ala Ile Val Lys Gly His Thr Lys Ile Val Ala Ala Trp Met 545 550 555 560 Glu Thr Ala Glu Val Ile Ala Ser His Tyr Glu Asn Asp Lys Asp Val 565 570 575 Val Arg Glu Leu Leu Ser Leu Ser Arg Asn Asn Ala Val Cys Ser Leu 580 585 590 Tyr Val Ala Ser Tyr Lys Thr Met Ser Lys Gln Val Ile Asp Val Tyr 595 600 605 Leu Asn Ala Ala Ile Arg Leu Ala Leu Gln His Gly Phe Thr Phe Asp 610 615 620 Glu Ile Leu Glu Gln Phe Thr Arg Asp Phe Asp Gly Lys Ser Phe Ser 625 630 635 640 Leu Ala Val Glu Lys Ala Asp Asp Ile Tyr Gly Ser Leu Ala Glu Asn 645 650 655 Ile Gln Asn Cys Gly Trp * 660 <210> 1566 <211> 2608 <212> DNA <213> Escherichia coli O157:H7 <400> 1566 tagagatagt gaacggtagc gcataatcat ttccttatta gcttgctgtc tgcgtcacac 60 tacgaccaaa cgctatcaga ttatttaata cattgttttt aatacaattc tgaaacaatc 120 tgaacacctg attgggtttg agtccattgc tggcgaccca ctcaaggttg ctcgtagctg 180 acttacttaa attacccaaa caatagacag tgtaaaccat ttgtgaggtt gagcgtgtta 240 tatggctgaa atgatcattt aaggtaaata tgatagttct gaaatggtgg tataaatcct 300 cctgtagagg ttaagagcat ctgcaagaag ccagtttcac atttataacg cgtgataaat 360 gaacgcggtt attgtctaat cattacaaat ttttcacatg cgataagaga tcctgctatt 420 aagatgattg ccaaaattac gttgtatttt tgaaaatgag cgaaatttga tagtcccagc 480 tttgactttt gataatatta tttatgctac agttgtgggt ataaaatata atctttttga 540 acaagtgaat ttgagctaag aataaatcaa gttgtttcag tgtttcgtta attaatatga 600 gtataaaagg tgttgtgctt ttataataat aaagcgcgag gagttcggtg gagtatcgtt 660 tttcttgggt gatttttaat atgataaaca atatatctga tcaagcgtca tcatttccat 720 gcacacaatt gaatcaaagt gataatttcc tcgattcact gagggaattt ttcgcgatat 780 taaattccag tcgtaagggt gagttgtcta catgggatac catctacttg catctgatat 840 tagtaataaa tgctgacagt gatctcataa aaaatgatgt gttgctcgcg gaaaatattc 900 caacagcgga ttatcaattt aatacatttt ttagtaatgc tttcgagact gatgttaaaa 960 aatatctggg taaatcagaa gataacgaag ttgaaataaa aacgggtaat gaaagaatct 1020 ctattggaat acgtaacaga tcgaatggaa aacttgaaag acaaaagttt cttttcccac 1080 tggactatga gaataaatta caacatcaat tagacaagca ttttacgatt gaatcgcacc 1140 cattattata caggcatact atgggtagta agattgcgaa tgtgattttt gaaaaattat 1200 acagtcgtat tgactttaac aaagaacaat atatatcctt tataaaggac gcgtttcttc 1260 atttttatga ttatagcagg cgatatgcaa ttaatgaaaa tattgcaaaa gacgctgtaa 1320 caaacaatat cgcattgatg agcacttttt atgacagtga taatacgtca ggtgaggttt 1380 taaataatga ttttacagaa gagtcatttg aaactgcgtt agatgtagag catacaatag 1440 tgcttggatt tgctgatgat aattttgaaa caaaacctgt tcattatcag gatttattaa 1500 cacgatttag tgcctttcaa gataccgtgt ttaatctgtt tcctgaaatg cactcttcgc 1560 attacaacga tatttgtagc gtaagtgtgg atatgacaaa gggaacgcaa tgcatgattc 1620 acttgatggt gaatgaagaa gttttcatgt ctctgcctgt tccagttgcc acgatggtac 1680 gtgaagatgc aagtaattta atcaatctta aaacactact caatgatggt tgctttatta 1740 aatatagtca ttttaatgac gtggcattaa taaagcaaaa cataagtaat ctctatttat 1800 cacacactgt tgtgaatgaa agcatattga aaaaatgttg ttttgaaaac ggcagtttag 1860 gtgatgttaa aataacaaat aacaaatagc aatatagtaa ataatgtatt caaaaatatt 1920 tcgtttagat ctgttaaaat taacaacgta aatactcatt ctttaaaatt tattaactgt 1980 cattttttta atgttgatat gataagagtt aatttcagca aatgtctttt tcatgactgt 2040 agcatgcatg gtgtcaagat aaaaccatgg ttgccagtaa aatggacaaa agagttaata 2100 aatgattatt tgtatggctg tttactctct ctgtactcta tctgtgcaag agatatatat 2160 aatatgaacg ccgggaataa cgtgaaggtt gctgcggatg cttttcttga aatactttat 2220 tctcttaaaa ataaatattg tattaaacta ttaagcgctc aggatcgggc gtttatatac 2280 gaatttgcaa gaatgatctt cgcttatatt aatgacaaaa gcattgagat cttattactt 2340 tcttgttttg cggcggcgga ccaaaaagca atccagcggt atatacctca ggcgcaagat 2400 ggggaagact ttaggaatca tttacaatat aagttgactc ttcccactca ttaatgttgc 2460 cggcacaaca taatagggca ggtaagcggt gctccataat gaaaccaata tccggttacg 2520 aaacagataa ttgtacaggc ttatgtagct gtttttgaca caatgagatg atttcctaaa 2580 ctgatcaaaa ccttcttccc aacatggc 2608 <210> 1567 <211> 414 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(648..1889) <400> 1567 Val Glu Tyr Arg Phe Ser Trp Val Ile Phe Asn Met Ile Asn Asn Ile 1 5 10 15 Ser Asp Gln Ala Ser Ser Phe Pro Cys Thr Gln Leu Asn Gln Ser Asp 20 25 30 Asn Phe Leu Asp Ser Leu Arg Glu Phe Phe Ala Ile Leu Asn Ser Ser 35 40 45 Arg Lys Gly Glu Leu Ser Thr Trp Asp Thr Ile Tyr Leu His Leu Ile 50 55 60 Leu Val Ile Asn Ala Asp Ser Asp Leu Ile Lys Asn Asp Val Leu Leu 65 70 75 80 Ala Glu Asn Ile Pro Thr Ala Asp Tyr Gln Phe Asn Thr Phe Phe Ser 85 90 95 Asn Ala Phe Glu Thr Asp Val Lys Lys Tyr Leu Gly Lys Ser Glu Asp 100 105 110 Asn Glu Val Glu Ile Lys Thr Gly Asn Glu Arg Ile Ser Ile Gly Ile 115 120 125 Arg Asn Arg Ser Asn Gly Lys Leu Glu Arg Gln Lys Phe Leu Phe Pro 130 135 140 Leu Asp Tyr Glu Asn Lys Leu Gln His Gln Leu Asp Lys His Phe Thr 145 150 155 160 Ile Glu Ser His Pro Leu Leu Tyr Arg His Thr Met Gly Ser Lys Ile 165 170 175 Ala Asn Val Ile Phe Glu Lys Leu Tyr Ser Arg Ile Asp Phe Asn Lys 180 185 190 Glu Gln Tyr Ile Ser Phe Ile Lys Asp Ala Phe Leu His Phe Tyr Asp 195 200 205 Tyr Ser Arg Arg Tyr Ala Ile Asn Glu Asn Ile Ala Lys Asp Ala Val 210 215 220 Thr Asn Asn Ile Ala Leu Met Ser Thr Phe Tyr Asp Ser Asp Asn Thr 225 230 235 240 Ser Gly Glu Val Leu Asn Asn Asp Phe Thr Glu Glu Ser Phe Glu Thr 245 250 255 Ala Leu Asp Val Glu His Thr Ile Val Leu Gly Phe Ala Asp Asp Asn 260 265 270 Phe Glu Thr Lys Pro Val His Tyr Gln Asp Leu Leu Thr Arg Phe Ser 275 280 285 Ala Phe Gln Asp Thr Val Phe Asn Leu Phe Pro Glu Met His Ser Ser 290 295 300 His Tyr Asn Asp Ile Cys Ser Val Ser Val Asp Met Thr Lys Gly Thr 305 310 315 320 Gln Cys Met Ile His Leu Met Val Asn Glu Glu Val Phe Met Ser Leu 325 330 335 Pro Val Pro Val Ala Thr Met Val Arg Glu Asp Ala Ser Asn Leu Ile 340 345 350 Asn Leu Lys Thr Leu Leu Asn Asp Gly Cys Phe Ile Lys Tyr Ser His 355 360 365 Phe Asn Asp Val Ala Leu Ile Lys Gln Asn Ile Ser Asn Leu Tyr Leu 370 375 380 Ser His Thr Val Val Asn Glu Ser Ile Leu Lys Lys Cys Cys Phe Glu 385 390 395 400 Asn Gly Ser Leu Gly Asp Val Lys Ile Thr Asn Asn Lys * 405 410 <210> 1568 <211> 152 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1999..2454) <400> 1568 Met Ile Arg Val Asn Phe Ser Lys Cys Leu Phe His Asp Cys Ser Met 1 5 10 15 His Gly Val Lys Ile Lys Pro Trp Leu Pro Val Lys Trp Thr Lys Glu 20 25 30 Leu Ile Asn Asp Tyr Leu Tyr Gly Cys Leu Leu Ser Leu Tyr Ser Ile 35 40 45 Cys Ala Arg Asp Ile Tyr Asn Met Asn Ala Gly Asn Asn Val Lys Val 50 55 60 Ala Ala Asp Ala Phe Leu Glu Ile Leu Tyr Ser Leu Lys Asn Lys Tyr 65 70 75 80 Cys Ile Lys Leu Leu Ser Ala Gln Asp Arg Ala Phe Ile Tyr Glu Phe 85 90 95 Ala Arg Met Ile Phe Ala Tyr Ile Asn Asp Lys Ser Ile Glu Ile Leu 100 105 110 Leu Leu Ser Cys Phe Ala Ala Ala Asp Gln Lys Ala Ile Gln Arg Tyr 115 120 125 Ile Pro Gln Ala Gln Asp Gly Glu Asp Phe Arg Asn His Leu Gln Tyr 130 135 140 Lys Leu Thr Leu Pro Thr His * 145 150 <210> 1569 <211> 2544 <212> DNA <213> Escherichia coli O157:H7 <400> 1569 ctgaagagta attagttatc ttttgctttt taacccgaat gttccctgcc atgcggtata 60 agttgcctgg cagggagtgt tcgggggcaa ttgctatttg cccacccggc acagatgaac 120 aaaattgccg ctatcggtac cttcagctta tgtcctgcgg ctggttggtt gggcgagata 180 gaatggattc gacatattcc cgctgttttt taaccacgcc agttttctcg caccttgctt 240 ggtcactccg ctcgatttca ggtaggatct ggcagtagac cactggaagc cgcgtttttt 300 actccacttt tcggctcccc ctgcgctgtt acgctcctcc tgggtcatat tcgcccattg 360 tacgatgtct ccgaaggtga acgtgaccca tttctgcggc cctgtcagct tcaactcacc 420 cagggcggta agcccgtcgt tcttcaggta attcctggca gtagttggcg cgaggtttct 480 ttccttacac cacttttcta aataaccaac cggttttcgc acatgcttgt ttaaggctgc 540 ccactggcgg atatgttcaa gggtgaattt ggcatattca tgcggcctgt ttacctttac 600 ctgtcccgcg tagttcaggc cgtgatcggt caggtaattt ctggcatttt tgatattaaa 660 atgattgcgc gtacaccatc ctgaaactcc ctgtagagcg tttcgcgcct gctggtccat 720 agccgcccat tttcgcatgt cgtctacagt caatttaaca tattgctgtg gctcgtccgc 780 ctctggctgg tcctcgatgg tctgcctggt gttgtttatg tcgtcatttg cagcatttgg 840 tgggatgttg cttgtattac acgattgctg taattccaca tcgttacgcc acgccagcgg 900 agacatattt ccaaattctc gcatgccatt gttggtaaag tgtgtttctt ctcttccgta 960 ttgctgggcc ggggagtagc gagctgcttc atgcaccctg ttttgacttt catccgtgag 1020 tattggccgt acggaccaga gatcaaaggt tccatattga ctgcgtgaca tcagggttgt 1080 gacaatggag tgaaacagct caagagtaat atttgtactg gtgcacacac cgctcttgct 1140 gactgcaatt ttcatgagat tgcccgtgtt gtcatgctct tgcgtcttcg tgaaggtgat 1200 ggtgaaaccg gcaacatcga aggtgaacgg ttcaggaagt tgcagatcat ttgcacttac 1260 caccggttgg aactgatgtc gatgcagttc ggttgtcatc gcagcagcca gcaagtgaac 1320 ctcttcagga accagtggag ctacagccat gcccgtgctg tagtccgcat cccttttgat 1380 ataattattc atctgcacca gaagcgtcaa agtttccaga caactactcg ggagttgttg 1440 cggtggaata taggttgctg cgctcgtatt gaggttggat attggtctca tgtaatgctc 1500 tccgtatcct tacagggtta atgattcgta ttaagtcgta gccatccgca tggctccggg 1560 cgattcagtc ggcgcaccag gatgtacact tcggatgcgt tcttgatgta gtaaacaatc 1620 cgctcattct ggtgttaatg gaaacacccg taaaaagcag gaggaatgcc agttattggc 1680 gaatttacaa tgctgccatc ggggtgagtt tcatgaagat tattattttt ttttacgcct 1740 tttatcatcg cgttaaataa taatttcttc ctgtgtttca taaagtatat agttacaatt 1800 actcgtgaat tttatcgata actcgacgtt agccttcagc cagagaaaaa ttaactcgca 1860 aattttttaa tttatcgtta ggggaatggg taaattatat tctcgaccct aattacaggg 1920 ttcatctgaa agcagtggcg tctcatctta ttacttctct ttctgtattc atgctagtgg 1980 gtttgtgata atgtcatagt agaaaaatcg tgagaaaaaa gccctgaaca attattaaat 2040 tattgatttt tgtgtgttgg tgtttttggt gattgatttt cacgatgatc tattacttct 2100 ggttaagatt tctattttta ttatgtgtga ctttattaat gcgcatcctg cttcgtttta 2160 tcgtgattta gaattgtatg tagcattagc cataaaatga tatcactggg aatataataa 2220 ggggaattat aattttgggg gataattagg cactatcaaa aatcgctcat tccagactta 2280 aatacacgtt ttctcctgtt taggttgtgg gcaaaaaatt cgatgaggag atgaggtata 2340 atttcattca caaccttatc actatctatt aataagcaaa aaacaacgtt cttttgtgaa 2400 acgactaact gaaaattcaa cccttcgggc acgctgcagc gagtttgtcg ccaccaacat 2460 tcgtacaagc ttcatctgcc gggcgaaacg tcagctaaat accttaaaat aatcgctttt 2520 ttctccggat ttgatctcct catt 2544 <210> 1570 <211> 448 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(148..1491) <400> 1570 Met Arg Pro Ile Ser Asn Leu Asn Thr Ser Ala Ala Thr Tyr Ile Pro 1 5 10 15 Pro Gln Gln Leu Pro Ser Ser Cys Leu Glu Thr Leu Thr Leu Leu Val 20 25 30 Gln Met Asn Asn Tyr Ile Lys Arg Asp Ala Asp Tyr Ser Thr Gly Met 35 40 45 Ala Val Ala Pro Leu Val Pro Glu Glu Val His Leu Leu Ala Ala Ala 50 55 60 Met Thr Thr Glu Leu His Arg His Gln Phe Gln Pro Val Val Ser Ala 65 70 75 80 Asn Asp Leu Gln Leu Pro Glu Pro Phe Thr Phe Asp Val Ala Gly Phe 85 90 95 Thr Ile Thr Phe Thr Lys Thr Gln Glu His Asp Asn Thr Gly Asn Leu 100 105 110 Met Lys Ile Ala Val Ser Lys Ser Gly Val Cys Thr Ser Thr Asn Ile 115 120 125 Thr Leu Glu Leu Phe His Ser Ile Val Thr Thr Leu Met Ser Arg Ser 130 135 140 Gln Tyr Gly Thr Phe Asp Leu Trp Ser Val Arg Pro Ile Leu Thr Asp 145 150 155 160 Glu Ser Gln Asn Arg Val His Glu Ala Ala Arg Tyr Ser Pro Ala Gln 165 170 175 Gln Tyr Gly Arg Glu Glu Thr His Phe Thr Asn Asn Gly Met Arg Glu 180 185 190 Phe Gly Asn Met Ser Pro Leu Ala Trp Arg Asn Asp Val Glu Leu Gln 195 200 205 Gln Ser Cys Asn Thr Ser Asn Ile Pro Pro Asn Ala Ala Asn Asp Asp 210 215 220 Ile Asn Asn Thr Arg Gln Thr Ile Glu Asp Gln Pro Glu Ala Asp Glu 225 230 235 240 Pro Gln Gln Tyr Val Lys Leu Thr Val Asp Asp Met Arg Lys Trp Ala 245 250 255 Ala Met Asp Gln Gln Ala Arg Asn Ala Leu Gln Gly Val Ser Gly Trp 260 265 270 Cys Thr Arg Asn His Phe Asn Ile Lys Asn Ala Arg Asn Tyr Leu Thr 275 280 285 Asp His Gly Leu Asn Tyr Ala Gly Gln Val Lys Val Asn Arg Pro His 290 295 300 Glu Tyr Ala Lys Phe Thr Leu Glu His Ile Arg Gln Trp Ala Ala Leu 305 310 315 320 Asn Lys His Val Arg Lys Pro Val Gly Tyr Leu Glu Lys Trp Cys Lys 325 330 335 Glu Arg Asn Leu Ala Pro Thr Thr Ala Arg Asn Tyr Leu Lys Asn Asp 340 345 350 Gly Leu Thr Ala Leu Gly Glu Leu Lys Leu Thr Gly Pro Gln Lys Trp 355 360 365 Val Thr Phe Thr Phe Gly Asp Ile Val Gln Trp Ala Asn Met Thr Gln 370 375 380 Glu Glu Arg Asn Ser Ala Gly Gly Ala Glu Lys Trp Ser Lys Lys Arg 385 390 395 400 Gly Phe Gln Trp Ser Thr Ala Arg Ser Tyr Leu Lys Ser Ser Gly Val 405 410 415 Thr Lys Gln Gly Ala Arg Lys Leu Ala Trp Leu Lys Asn Ser Gly Asn 420 425 430 Met Ser Asn Pro Phe Tyr Leu Ala Gln Pro Thr Ser Arg Arg Thr * 435 440 445 <210> 1571 <211> 2506 <212> DNA <213> Escherichia coli O157:H7 <400> 1571 gatgcgtttt gccatttcgc cctgaatgct ggtatcgaat gccggatgcg gcgtaaacgc 60 ctgatccggc ttatcaaaat gtgcaaattc aatacgttgt gattcagttg taggcatgat 120 aagacgcgtc agcgtcgcat caggcatcaa cgcacaacta cagttcattc agtacatact 180 ggaaacggca tgtagaatca attggctcac ggctactggt attcacctgt accacaatgt 240 cgtgtagctt tctatccgtc aatggttgac gtgagggggt gactgtcacc tttgcattat 300 cacaaccata cgaggtaaag gttaataagt cagaaacagc acgacaatat gcccctctgg 360 aatcaaaaat actgccatcg cagagtttgc cgctttccat caggtaggtc gaaagcgtag 420 tcgtgattgt cgaaccatcg gattgcaatc gcagcgcttt attatggcta acataattat 480 cactccagga tatatcaaac gaagcgacgg gaattgtcgg gcaaatagaa tcatgaactg 540 ttgggcttgt atacgtacca aatccaaatg cctcagatac tgaataaaat gaggcaatcc 600 acggacaacc ataattatca gattctacag tgacgttaaa agtcatatat gcacagacaa 660 agacacgagt attgatacca gggcaatttg aggtgtccgt acgtctataa tcagtcaaaa 720 ccagtgtcgg tgccgggcca gatccgctcc aggatattaa cttgagggtg tcgccttttc 780 ttgcattgga gttgtattgt ccgtagctta cttctcccgg cgtcactacc gtgacataga 840 aatataaact gccggaagca gtaacgtttt tcatcgcata ataaatttta gtactggaaa 900 agcttgcact catgagttta tcaccggcat agcactttgg tgtttctaaa ctgagagcaa 960 gtaatatcag acttgtcaaa aatatcgtcc attttttcat tttaaaaata ctcaaaagtt 1020 accgtcattg tggcggtgaa atcacccgat gtaacatttc gtccatttac ggtctgtaac 1080 caggcattaa aattgacact gttatttccc tgatttaatg gaaatgaggc acctgtggta 1140 ctgttaatag gtacagccgc ccctccggca gtttcaatgc caatcccaac acccgttgca 1200 gaagatgacg aatcaatcga cagaaatcct ggtaagtcgg tatcttctgt tcccatcaag 1260 gtcaccttga cattaaacgc cgtggtgctt ttgcaatctt tcaactgaaa aactaacggt 1320 acgcgatctg actgaccacg ttgcattaaa tcgctggcag caattgtggg gaaatgaatt 1380 tctgcaagta agttgccatt gattacagga gtacaggatt taccaagcaa attaccggta 1440 aaatgcaggt tatcggcagc tggggccgtt ccgctgaaca atatcagacc actgataagc 1500 gcccacgcac ggttattctt cattggtaat ccacctgtaa cgtagcccat gcttcaaagt 1560 ctgactcggg taagtcgaca ccgctctttt ttacgggtac tgccgttagt accggaaggg 1620 atgtttcatt caccactaag ggcgtatgca gcttaaaatc gctcccggct tgtttgaggt 1680 gtattcctaa tccattgaga tccgtggcta cggccgaatc gtcaaagtca ctctgcgtac 1740 cactccaggt caacgtcatt tccatttgag ggtcacggac agcggtatcg caggtaatgg 1800 tatacggcac gacctgttcg taattgctac cgttaatgtc atcaatattc acgtcccgaa 1860 acgtcaactc tatattttgc ccattactaa tagagcaatt gggtggctgc actaaataac 1920 catgaaaaga gacattcgag agcgccataa agctaaagct ccacaacatt aagagagaga 1980 tccgtttcat tgataatcca ccacaattgt ggcactggcg ctaaattccg ccgccgttag 2040 cgatacaccg ctctgcacga caggaaccgc ttccagagcc agtgcgccag atgaaaagtt 2100 aaacggtaac catgcgccag gcgttaaatc caaaatggag tgatcgctta ctttctgaat 2160 acggatacca aaaccggcaa tacccgtatc gattaccgtt tctccgttaa ttacggttgt 2220 ggttgcctgc atatttaagc gcaggtcgtc cattgccaga ttgttgcaca caagcgagta 2280 gtcaatgggg cgtttgtaac ttaccccatc gatcttggaa atgaagacat taccaaactc 2340 cacgctcgca cccgttaccg tacagggcgg cggggcatca acgagcacac gcaagaccat 2400 cgcaaccgat ttactccccg ccattacagg cgtgctcaca atgctacaca gcaataacca 2460 cgcccaggcc gaataagctc ctttcatgct attgctccta tccctg 2506 <210> 1572 <211> 281 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(158..1000) <400> 1572 Met Lys Lys Trp Thr Ile Phe Leu Thr Ser Leu Ile Leu Leu Ala Leu 1 5 10 15 Ser Leu Glu Thr Pro Lys Cys Tyr Ala Gly Asp Lys Leu Met Ser Ala 20 25 30 Ser Phe Ser Ser Thr Lys Ile Tyr Tyr Ala Met Lys Asn Val Thr Ala 35 40 45 Ser Gly Ser Leu Tyr Phe Tyr Val Thr Val Val Thr Pro Gly Glu Val 50 55 60 Ser Tyr Gly Gln Tyr Asn Ser Asn Ala Arg Lys Gly Asp Thr Leu Lys 65 70 75 80 Leu Ile Ser Trp Ser Gly Ser Gly Pro Ala Pro Thr Leu Val Leu Thr 85 90 95 Asp Tyr Arg Arg Thr Asp Thr Ser Asn Cys Pro Gly Ile Asn Thr Arg 100 105 110 Val Phe Val Cys Ala Tyr Met Thr Phe Asn Val Thr Val Glu Ser Asp 115 120 125 Asn Tyr Gly Cys Pro Trp Ile Ala Ser Phe Tyr Ser Val Ser Glu Ala 130 135 140 Phe Gly Phe Gly Thr Tyr Thr Ser Pro Thr Val His Asp Ser Ile Cys 145 150 155 160 Pro Thr Ile Pro Val Ala Ser Phe Asp Ile Ser Trp Ser Asp Asn Tyr 165 170 175 Val Ser His Asn Lys Ala Leu Arg Leu Gln Ser Asp Gly Ser Thr Ile 180 185 190 Thr Thr Thr Leu Ser Thr Tyr Leu Met Glu Ser Gly Lys Leu Cys Asp 195 200 205 Gly Ser Ile Phe Asp Ser Arg Gly Ala Tyr Cys Arg Ala Val Ser Asp 210 215 220 Leu Leu Thr Phe Thr Ser Tyr Gly Cys Asp Asn Ala Lys Val Thr Val 225 230 235 240 Thr Pro Ser Arg Gln Pro Leu Thr Asp Arg Lys Leu His Asp Ile Val 245 250 255 Val Gln Val Asn Thr Ser Ser Arg Glu Pro Ile Asp Ser Thr Cys Arg 260 265 270 Phe Gln Tyr Val Leu Asn Glu Leu * 275 280 <210> 1573 <211> 183 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1002..1550) <400> 1573 Met Gly Tyr Val Thr Gly Gly Leu Pro Met Lys Asn Asn Arg Ala Trp 1 5 10 15 Ala Leu Ile Ser Gly Leu Ile Leu Phe Ser Gly Thr Ala Pro Ala Ala 20 25 30 Asp Asn Leu His Phe Thr Gly Asn Leu Leu Gly Lys Ser Cys Thr Pro 35 40 45 Val Ile Asn Gly Asn Leu Leu Ala Glu Ile His Phe Pro Thr Ile Ala 50 55 60 Ala Ser Asp Leu Met Gln Arg Gly Gln Ser Asp Arg Val Pro Leu Val 65 70 75 80 Phe Gln Leu Lys Asp Cys Lys Ser Thr Thr Ala Phe Asn Val Lys Val 85 90 95 Thr Leu Met Gly Thr Glu Asp Thr Asp Leu Pro Gly Phe Leu Ser Ile 100 105 110 Asp Ser Ser Ser Ser Ala Thr Gly Val Gly Ile Gly Ile Glu Thr Ala 115 120 125 Gly Gly Ala Ala Val Pro Ile Asn Ser Thr Thr Gly Ala Ser Phe Pro 130 135 140 Leu Asn Gln Gly Asn Asn Ser Val Asn Phe Asn Ala Trp Leu Gln Thr 145 150 155 160 Val Asn Gly Arg Asn Val Thr Ser Gly Asp Phe Thr Ala Thr Met Thr 165 170 175 Val Thr Phe Glu Tyr Phe * 180 <210> 1574 <211> 157 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1520..1990) <400> 1574 Met Lys Arg Ile Ser Leu Leu Met Leu Trp Ser Phe Ser Phe Met Ala 1 5 10 15 Leu Ser Asn Val Ser Phe His Gly Tyr Leu Val Gln Pro Pro Asn Cys 20 25 30 Ser Ile Ser Asn Gly Gln Asn Ile Glu Leu Thr Phe Arg Asp Val Asn 35 40 45 Ile Asp Asp Ile Asn Gly Ser Asn Tyr Glu Gln Val Val Pro Tyr Thr 50 55 60 Ile Thr Cys Asp Thr Ala Val Arg Asp Pro Gln Met Glu Met Thr Leu 65 70 75 80 Thr Trp Ser Gly Thr Gln Ser Asp Phe Asp Asp Ser Ala Val Ala Thr 85 90 95 Asp Leu Asn Gly Leu Gly Ile His Leu Lys Gln Ala Gly Ser Asp Phe 100 105 110 Lys Leu His Thr Pro Leu Val Val Asn Glu Thr Ser Leu Pro Val Leu 115 120 125 Thr Ala Val Pro Val Lys Lys Ser Gly Val Asp Leu Pro Glu Ser Asp 130 135 140 Phe Glu Ala Trp Ala Thr Leu Gln Val Asp Tyr Gln * 145 150 155 <210> 1575 <211> 167 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1987..2487) <400> 1575 Met Lys Gly Ala Tyr Ser Ala Trp Ala Trp Leu Leu Leu Cys Ser Ile 1 5 10 15 Val Ser Thr Pro Val Met Ala Gly Ser Lys Ser Val Ala Met Val Leu 20 25 30 Arg Val Leu Val Asp Ala Pro Pro Pro Cys Thr Val Thr Gly Ala Ser 35 40 45 Val Glu Phe Gly Asn Val Phe Ile Ser Lys Ile Asp Gly Val Ser Tyr 50 55 60 Lys Arg Pro Ile Asp Tyr Ser Leu Val Cys Asn Asn Leu Ala Met Asp 65 70 75 80 Asp Leu Arg Leu Asn Met Gln Ala Thr Thr Thr Val Ile Asn Gly Glu 85 90 95 Thr Val Ile Asp Thr Gly Ile Ala Gly Phe Gly Ile Arg Ile Gln Lys 100 105 110 Val Ser Asp His Ser Ile Leu Asp Leu Thr Pro Gly Ala Trp Leu Pro 115 120 125 Phe Asn Phe Ser Ser Gly Ala Leu Ala Leu Glu Ala Val Pro Val Val 130 135 140 Gln Ser Gly Val Ser Leu Thr Ala Ala Glu Phe Ser Ala Ser Ala Thr 145 150 155 160 Ile Val Val Asp Tyr Gln * 165 <210> 1576 <211> 2450 <212> DNA <213> Escherichia coli O157:H7 <400> 1576 gtaagcgtac atcctgaacc gtctggtcag aatctgacga attagacaaa gtggtgtcca 60 ccaaataagt agtgggaacc aaagtatcag atatgcagaa aaatgtgact cccggcaggc 120 gaaaaggctg ccctaattat cctcccgaat ttaaacagca gctcgttgct gcctcctgtg 180 aacccgggat atccatctca aaacttgctc ttgaaaatgg cattaacgca aatctgttgt 240 tcaaatggcg acaacaatgg cgcgagggaa agctgctatt accttcttca gagagccccc 300 agctacttcc tgtgactctc gatgcagctg ccgaacagcc agaatcgctc gcagaggacc 360 cggaaaccct cagtatcagc tgtgaggtaa cgttccggca cgggacgctc cgcttcaatg 420 gcaatgtcag cgaaaagctc ctgactctgc tgatacagga actgaagcga tgatcccgtt 480 accttccggg accaaaattt ggctggttgc cggtatcacc gatatgagaa atggcttcaa 540 cggcctggct gcgaaagtac aaacggcgct gaaagacgat cccatgtccg gccatgtttt 600 cattttccgg ggccgcagcg gcagtcaggt taaactgctg tggtccaccg gtgacggact 660 gtgcctcctg accaaacggc tggagcgtgg gcgcttcgcc tggccgtcag cccgtgatgg 720 caaagtgttc cttacgcagg cgcagctggc gatgctgctg gaaggtatcg actggcgaca 780 gcctaagcgg ctgctgacct ccctgaccat gctgtaaatc tctttatcct ggttgtcaca 840 gaataagccc ggtaaaatac gggcttatga acgacatctc ttctgacgac atcttcctgc 900 tgaaacagcg cctggccgaa caggaagcgc tgatccacgc cctgcaggaa aagctgagca 960 accgggagcg cgaaatagac catctgcagg cgcagctgga taaactccgc cggatgaact 1020 tcggcagtcg ttccgaaaaa gtctcccgcc gtatcgcaca aatggaagcc gatctgaacc 1080 ggcttcagaa agagagcgat acgctgactg gtagggtgta tgacccggca gtacagcgtc 1140 cgttgcgtca gacccgcacc cgtaagccgt tccctgaatc actaccccgt gacgaaaagc 1200 gactgttgcc tgcggcgccg tgctgcccga actgcggcgg ttcactgagc tatctgggcg 1260 aggataccgc cgaacagctg gagttgatgc gtagcgcctt ccgggttatc cggacggtac 1320 gggaaaaaca tgcctgtact cagtgcgatg ccatcgtgca ggcacctgca ccttcgcggc 1380 ccatcgagcg gggtatcgcc ggaccggggc tgctggcccg cgtgctgacc tcgaagtatg 1440 cagagcacac cccgctgtat cgccagtcag aaatatacgg ccggcaaggt gtggagctga 1500 ggcgttcact gctgtcgggc tgggtggatg catgctgccg gctgctgtct ccgctggaag 1560 aggcgcttca tggctatgtc atgactgacg gcaaactcca tgccgatgat accccggtcc 1620 aggtactgct gccgggtaat aagaagacga agaccgggcg gttgtgggcg tatgttcgtg 1680 atgaccgcaa tgcagggtca gcgttggcac ctgcagtgtg gttcgcttac agcccggaca 1740 gaaaaggcat ccatccgcag actcatcttg cctgcttcag cggtgtgctg caagcggatg 1800 cgtacgccgg gttcaacgag ctgtatcgca atggtgggat aacggaagct gcctgctggg 1860 ctcatgcccg ccgaaagatc cacgatgtgc acgtccgcat cccgtcagca ctgacggaag 1920 aagccctgga gcagatcggt cagttgtacg ccatagaggc ggatataagg ggaatgccgg 1980 cagagcagcg gcttgctgaa cgtcagcgaa aaacgaaacc gttgttgaaa tccctggaaa 2040 gctggttgcg tgaaaagatg aagaccctgt cgcgacactc agagttggcg aaggcgttcg 2100 cgtacgcact taaccagtgg ccggcactga cgtactatgc gaacgatggc tgggtggaaa 2160 tcgacaacaa catcgctgaa aatgccctgc gggcggtcag tctgggtcgt aaaaacttcc 2220 tgttcttcgg ctctgatcat ggtggtgagc ggggagcgct actgtacagc ctgatcggga 2280 cgtgcaaact gaatgacgtg gatccagaaa gctaccttcg ccatgtgctt ggcgtcatag 2340 cagactggcc ggtcaaccgg gtcagcgaac tgcttccgtg gcgcatagca ctgccagctg 2400 aataacacat ccccgtcaat acggccctcg ctgtacgctt acagtgattg 2450 <210> 1577 <211> 134 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(72..473) <400> 1577 Val Gly Thr Lys Val Ser Asp Met Gln Lys Asn Val Thr Pro Gly Arg 1 5 10 15 Arg Lys Gly Cys Pro Asn Tyr Pro Pro Glu Phe Lys Gln Gln Leu Val 20 25 30 Ala Ala Ser Cys Glu Pro Gly Ile Ser Ile Ser Lys Leu Ala Leu Glu 35 40 45 Asn Gly Ile Asn Ala Asn Leu Leu Phe Lys Trp Arg Gln Gln Trp Arg 50 55 60 Glu Gly Lys Leu Leu Leu Pro Ser Ser Glu Ser Pro Gln Leu Leu Pro 65 70 75 80 Val Thr Leu Asp Ala Ala Ala Glu Gln Pro Glu Ser Leu Ala Glu Asp 85 90 95 Pro Glu Thr Leu Ser Ile Ser Cys Glu Val Thr Phe Arg His Gly Thr 100 105 110 Leu Arg Phe Asn Gly Asn Val Ser Glu Lys Leu Leu Thr Leu Leu Ile 115 120 125 Gln Glu Leu Lys Arg * 130 <210> 1578 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(470..817) <400> 1578 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Asp Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 1579 <211> 513 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(867..2405) <400> 1579 Met Asn Asp Ile Ser Ser Asp Asp Ile Phe Leu Leu Lys Gln Arg Leu 1 5 10 15 Ala Glu Gln Glu Ala Leu Ile His Ala Leu Gln Glu Lys Leu Ser Asn 20 25 30 Arg Glu Arg Glu Ile Asp His Leu Gln Ala Gln Leu Asp Lys Leu Arg 35 40 45 Arg Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala 50 55 60 Gln Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu 65 70 75 80 Thr Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr 85 90 95 Arg Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg 100 105 110 Leu Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser 115 120 125 Tyr Leu Gly Glu Asp Thr Ala Glu Gln Leu Glu Leu Met Arg Ser Ala 130 135 140 Phe Arg Val Ile Arg Thr Val Arg Glu Lys His Ala Cys Thr Gln Cys 145 150 155 160 Asp Ala Ile Val Gln Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly 165 170 175 Ile Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Ser Lys Tyr Ala 180 185 190 Glu His Thr Pro Leu Tyr Arg Gln Ser Glu Ile Tyr Gly Arg Gln Gly 195 200 205 Val Glu Leu Arg Arg Ser Leu Leu Ser Gly Trp Val Asp Ala Cys Cys 210 215 220 Arg Leu Leu Ser Pro Leu Glu Glu Ala Leu His Gly Tyr Val Met Thr 225 230 235 240 Asp Gly Lys Leu His Ala Asp Asp Thr Pro Val Gln Val Leu Leu Pro 245 250 255 Gly Asn Lys Lys Thr Lys Thr Gly Arg Leu Trp Ala Tyr Val Arg Asp 260 265 270 Asp Arg Asn Ala Gly Ser Ala Leu Ala Pro Ala Val Trp Phe Ala Tyr 275 280 285 Ser Pro Asp Arg Lys Gly Ile His Pro Gln Thr His Leu Ala Cys Phe 290 295 300 Ser Gly Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr 305 310 315 320 Arg Asn Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg 325 330 335 Lys Ile His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu 340 345 350 Ala Leu Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg 355 360 365 Gly Met Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys 370 375 380 Pro Leu Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr 385 390 395 400 Leu Ser Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn 405 410 415 Gln Trp Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile 420 425 430 Asp Asn Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg 435 440 445 Lys Asn Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala 450 455 460 Leu Leu Tyr Ser Leu Ile Gly Thr Cys Lys Leu Asn Asp Val Asp Pro 465 470 475 480 Glu Ser Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val 485 490 495 Asn Arg Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu 500 505 510 * <210> 1580 <211> 2450 <212> DNA <213> Escherichia coli O157:H7 <400> 1580 gtaagcgtac agcctgaacc gtctggtcag aatctgacga attagacaaa gtggtgtcca 60 ccaaataagt agtgggaacc aaagtatcag atatgcagaa aaatgtgact cccggcaggc 120 gaaaaggctg ccctaattat cctcccgaat ttaaacagca gctcgttgct gcctcctgtg 180 aacccgggat atccatctca aaacttgctc ttgaaaatgg cattaacgca aatctgttgt 240 tcaaatggcg acaacaatgg cgcgagggaa agctgctatt accttcttca gagagccccc 300 agctacttcc tgtgactctc gatgcagctg ccgaacagcc agaatcgctc gcagaggacc 360 cggaaaccct cagtatcagc tgtgaggtaa cgttccggca cgggacgctc cgcttcaatg 420 gcaatgtcag cgaaaagctc ctgactctgc tgatacagga actgaagcga tgatcccgtt 480 accttccggg accaaaattt ggctggttgc cggtatcacc gatatgagaa atggcttcaa 540 cggcctggct gcgaaagtac aaacggcgct gaaagacgat cccatgtccg gccatgtttt 600 cattttccgg ggccgcagcg gcagtcaggt taaactgctg tggtccaccg gtgacggact 660 gtgcctcctg accaaacggc tggagcgtgg gcgcttcgcc tggccgtcag cccgtgatgg 720 caaagtgttc cttacgcagg cgcagctggc gatgctgctg gaaggtatcg actggcgaca 780 gcctaagcgg ctgctgacct ccctgaccat gctgtaaatc tctttatcct ggttgtcaca 840 gaataagccc ggtaaaatac gggcttatga acgacatctc ttctgacgac atcttcctgc 900 tgaaacagcg cctggccgaa caggaagcgc tgatccacgc cctgcaggaa aagctgagca 960 accgggagcg cgaaatagac catctgcagg cgcagctgga taaactccgc cggatgaact 1020 tcggcagtcg ttccgaaaaa gtctcccgcc gtatcgcaca aatggaagcc gatctgaacc 1080 ggcttcagaa agagagcgat acgctgactg gtagggtgta tgacccggca gtacagcgtc 1140 cgttgcgtca gacccgcacc cgtaagccgt tccctgaatc actaccccgt gacgaaaagc 1200 gactgttgcc tgcggcgccg tgctgcccga actgcggcgg ttcactgagc tatctgggcg 1260 aggataccgc cgaacagctg gagttgatgc gtagcgcctt ccgggttatc cggacggtac 1320 gggaaaaaca tgcctgtact cagtgcgatg ccatcgtgca ggcacctgca ccttcgcggc 1380 ccatcgagcg gggtatcgcc ggaccggggc tgctggcccg cgtgctgacc tcgaagtatg 1440 cagagcacac cccgctgtat cgccagtcag aaatatacgg ccggcaaggt gtggagctga 1500 ggcgttcact gctgtcgggc tgggtggatg catgctgccg gctgctgtct ccgctggaag 1560 aggcgcttca tggctatgtc atgactgacg gcaaactcca tgccgatgat accccggtcc 1620 aggtactgct gccgggtaat aagaagacga agaccgggcg gttgtgggcg tatgttcgtg 1680 atgaccgcaa tgcagggtca gcgttggcac ctgcagtgtg gttcgcttac agcccggaca 1740 gaaaaggcat ccatccgcag actcatcttg cctgcttcag cggtgtgctg caagcggatg 1800 cgtacgccgg gttcaacgag ctgtatcgca atggtgggat aacggaagct gcctgctggg 1860 ctcatgcccg ccgaaagatc cacgatgtgc acgtccgcat cccgtcagca ctgacggaag 1920 aagccctgga gcagatcggt cagttgtacg ccatagaggc ggatataagg ggaatgccgg 1980 cagagcagcg gcttgctgaa cgtcagcgaa aaacgaaacc gttgttgaaa tccctggaaa 2040 gctggttgcg tgaaaagatg aagaccctgt cgcgacactc agagttggcg aaggcgttcg 2100 cgtacgcact taaccagtgg ccggcactga cgtactatgc gaacgatggc tgggtggaaa 2160 tcgacaacaa catcgctgaa aatgccctgc gggcggtcag tctgggtcgt aaaaacttcc 2220 tgttcttcgg ctctgatcat ggtggtgagc ggggagcgct actgtacagc ctgatcggga 2280 cgtgcaaact gaatgacgtg gatccagaaa gctaccttcg ccatgtgctt ggcgtcatag 2340 cagactggcc ggtcaaccgg gtcagcgaac tgcttccgtg gcgcatagca ctgccagctg 2400 aataacacat ccccgtcaat acggccctcg ctgtacgctt acgaacaacc 2450 <210> 1581 <211> 134 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(72..473) <400> 1581 Val Gly Thr Lys Val Ser Asp Met Gln Lys Asn Val Thr Pro Gly Arg 1 5 10 15 Arg Lys Gly Cys Pro Asn Tyr Pro Pro Glu Phe Lys Gln Gln Leu Val 20 25 30 Ala Ala Ser Cys Glu Pro Gly Ile Ser Ile Ser Lys Leu Ala Leu Glu 35 40 45 Asn Gly Ile Asn Ala Asn Leu Leu Phe Lys Trp Arg Gln Gln Trp Arg 50 55 60 Glu Gly Lys Leu Leu Leu Pro Ser Ser Glu Ser Pro Gln Leu Leu Pro 65 70 75 80 Val Thr Leu Asp Ala Ala Ala Glu Gln Pro Glu Ser Leu Ala Glu Asp 85 90 95 Pro Glu Thr Leu Ser Ile Ser Cys Glu Val Thr Phe Arg His Gly Thr 100 105 110 Leu Arg Phe Asn Gly Asn Val Ser Glu Lys Leu Leu Thr Leu Leu Ile 115 120 125 Gln Glu Leu Lys Arg * 130 <210> 1582 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(470..817) <400> 1582 Met Ile Pro Leu Pro Ser Gly Thr Lys Ile Trp Leu Val Ala Gly Ile 1 5 10 15 Thr Asp Met Arg Asn Gly Phe Asn Gly Leu Ala Ala Lys Val Gln Thr 20 25 30 Ala Leu Lys Asp Asp Pro Met Ser Gly His Val Phe Ile Phe Arg Gly 35 40 45 Arg Ser Gly Ser Gln Val Lys Leu Leu Trp Ser Thr Gly Asp Gly Leu 50 55 60 Cys Leu Leu Thr Lys Arg Leu Glu Arg Gly Arg Phe Ala Trp Pro Ser 65 70 75 80 Ala Arg Asp Gly Lys Val Phe Leu Thr Gln Ala Gln Leu Ala Met Leu 85 90 95 Leu Glu Gly Ile Asp Trp Arg Gln Pro Lys Arg Leu Leu Thr Ser Leu 100 105 110 Thr Met Leu * 115 <210> 1583 <211> 513 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(867..2405) <400> 1583 Met Asn Asp Ile Ser Ser Asp Asp Ile Phe Leu Leu Lys Gln Arg Leu 1 5 10 15 Ala Glu Gln Glu Ala Leu Ile His Ala Leu Gln Glu Lys Leu Ser Asn 20 25 30 Arg Glu Arg Glu Ile Asp His Leu Gln Ala Gln Leu Asp Lys Leu Arg 35 40 45 Arg Met Asn Phe Gly Ser Arg Ser Glu Lys Val Ser Arg Arg Ile Ala 50 55 60 Gln Met Glu Ala Asp Leu Asn Arg Leu Gln Lys Glu Ser Asp Thr Leu 65 70 75 80 Thr Gly Arg Val Tyr Asp Pro Ala Val Gln Arg Pro Leu Arg Gln Thr 85 90 95 Arg Thr Arg Lys Pro Phe Pro Glu Ser Leu Pro Arg Asp Glu Lys Arg 100 105 110 Leu Leu Pro Ala Ala Pro Cys Cys Pro Asn Cys Gly Gly Ser Leu Ser 115 120 125 Tyr Leu Gly Glu Asp Thr Ala Glu Gln Leu Glu Leu Met Arg Ser Ala 130 135 140 Phe Arg Val Ile Arg Thr Val Arg Glu Lys His Ala Cys Thr Gln Cys 145 150 155 160 Asp Ala Ile Val Gln Ala Pro Ala Pro Ser Arg Pro Ile Glu Arg Gly 165 170 175 Ile Ala Gly Pro Gly Leu Leu Ala Arg Val Leu Thr Ser Lys Tyr Ala 180 185 190 Glu His Thr Pro Leu Tyr Arg Gln Ser Glu Ile Tyr Gly Arg Gln Gly 195 200 205 Val Glu Leu Arg Arg Ser Leu Leu Ser Gly Trp Val Asp Ala Cys Cys 210 215 220 Arg Leu Leu Ser Pro Leu Glu Glu Ala Leu His Gly Tyr Val Met Thr 225 230 235 240 Asp Gly Lys Leu His Ala Asp Asp Thr Pro Val Gln Val Leu Leu Pro 245 250 255 Gly Asn Lys Lys Thr Lys Thr Gly Arg Leu Trp Ala Tyr Val Arg Asp 260 265 270 Asp Arg Asn Ala Gly Ser Ala Leu Ala Pro Ala Val Trp Phe Ala Tyr 275 280 285 Ser Pro Asp Arg Lys Gly Ile His Pro Gln Thr His Leu Ala Cys Phe 290 295 300 Ser Gly Val Leu Gln Ala Asp Ala Tyr Ala Gly Phe Asn Glu Leu Tyr 305 310 315 320 Arg Asn Gly Gly Ile Thr Glu Ala Ala Cys Trp Ala His Ala Arg Arg 325 330 335 Lys Ile His Asp Val His Val Arg Ile Pro Ser Ala Leu Thr Glu Glu 340 345 350 Ala Leu Glu Gln Ile Gly Gln Leu Tyr Ala Ile Glu Ala Asp Ile Arg 355 360 365 Gly Met Pro Ala Glu Gln Arg Leu Ala Glu Arg Gln Arg Lys Thr Lys 370 375 380 Pro Leu Leu Lys Ser Leu Glu Ser Trp Leu Arg Glu Lys Met Lys Thr 385 390 395 400 Leu Ser Arg His Ser Glu Leu Ala Lys Ala Phe Ala Tyr Ala Leu Asn 405 410 415 Gln Trp Pro Ala Leu Thr Tyr Tyr Ala Asn Asp Gly Trp Val Glu Ile 420 425 430 Asp Asn Asn Ile Ala Glu Asn Ala Leu Arg Ala Val Ser Leu Gly Arg 435 440 445 Lys Asn Phe Leu Phe Phe Gly Ser Asp His Gly Gly Glu Arg Gly Ala 450 455 460 Leu Leu Tyr Ser Leu Ile Gly Thr Cys Lys Leu Asn Asp Val Asp Pro 465 470 475 480 Glu Ser Tyr Leu Arg His Val Leu Gly Val Ile Ala Asp Trp Pro Val 485 490 495 Asn Arg Val Ser Glu Leu Leu Pro Trp Arg Ile Ala Leu Pro Ala Glu 500 505 510 * <210> 1584 <211> 2305 <212> DNA <213> Escherichia coli O157:H7 <400> 1584 ggatggcgga gaacgccgat actcgcggca ttgaacgcgt aaactatctg gcactgctgg 60 cactcggcac tttctatttt ctctgcgctt tcctgcctat ctacttcggc gcggaacatg 120 caaaaaccat cattgatgtc ctgccgcaac gattaatcga cggcctcggc gtcgcgggcg 180 gcatcatgcc agcaatcggt tttgccgtgc tgctgaaaat catgatgaaa aacgtctaca 240 tcccctactt catcctgggc tttgttgccg cagcctggct caagttaccg gtgctggcta 300 ttgctgccgc cgcgctggcg atggcgctga tcgatctgct gcgtaaatct cctgaaccga 360 ctcaacctgc ggcacagaaa gaggaatttg aagatggcat ctaatcaaac caccctgccg 420 aacgtcagtg aaaacgaaga aacattgctg actggcgtca atgaaaacgt gtatgaagat 480 cagagcattg gcgcggagct gacgaaaaaa gatatcaatc gcgtcgcctg gcgttccatg 540 ctgttacaag cgtcttttaa ctacgaacgt atgcaggctt ccggctggtt gtacggtctg 600 ctgcctgctc tgaaaaagat ccacactaat aaacgcgacc tggcgcgcgc catgaagggg 660 catatgggtt tcttcaatac ccatccgttt ctggtgacat ttgttatcgg cattatcctt 720 gcgatggagc gttctaagca ggacgttaac agtattcaga gcaccaaaat tgccgtcggt 780 gcgccgctcg gcgggattgg cgatgcaatg ttctggctaa cgctactgcc gatttgtggc 840 gggattggag ccagtctggc attgcaaggc tccattcttg gcgcagtcgt ctttattgtg 900 ctgttcaacg tggtccacct ggggctgcgt tttggtctgg cgcattatgc ttaccgcatg 960 ggcgtggcgg cgattccact cattaaagct aataccaaaa aagtcggcca tgctgcgtct 1020 atcgttggga tgacggtaat cggtgcgctg gtggcaacct atgttcgttt aagcaccacg 1080 ctggaaatca cagcgggcga cgcagtggtt aagttacagg ctgatgttat cgacaaactg 1140 atgcctgcct tcttaccgtt ggtctacacc ctgaccatgt tttggttggt acgccgcggc 1200 tggagtccgc tgcgtctgat tgcagttacc gtggttctcg gcatcgttgg taaattctgc 1260 catttccttt aaatacaatg aggtattaga tgttaagtat tattttgaca gggcatggcg 1320 ggtttgccag cggcatggaa aaagcaatga agcaaattct cggtgagcaa tcgcagttta 1380 tcgccatcga ttttccggaa acctcaagca ccgcgctgct tacatcgcag cttgaagagg 1440 ccatcgccca actggattgt gaagacggca ttgtttttct gacggatttg ctgggcggca 1500 cgccgtttcg cgtagcttca acgctggcga tgcaaaaacc gggctgtgaa gtgatcaccg 1560 gcaccaattt gcaactgcta ctggagatgg tgctggagcg cgaagggtta agcggtgaag 1620 aattccgtgt acaggcgctg gagtgtggac atcgtgggct gaccagtctg gtggacgagt 1680 taggccgctg ccatgaagaa tgtccggtcg aggaagggat atgacacacg ttctgcgcgc 1740 cagaaggctg ctgactgaag agggatggct cgatgaccat cagttgcgta ttgctgacgg 1800 tgtcatcgca gcaatcgaac cgattccagt gagcgtgact gaacgcgatg cggaactgct 1860 ctgccccgct tacatcgaca cccatgtaca cggtggtgcg ggcgttgatg taatggatga 1920 cgcgccggat gtactcgaca agctggcaat gcacaaggca cgcgaaggtg tcggcagttg 1980 gttgccgact accgtaaccg cgccgcttag taccattcat gcggcgctga aacgtattgc 2040 tcaacgttgc caacgcggcg gacctggtgc gcaagtgctg gggagttatc tcgaaggacc 2100 gtacttcacg ccgcagaata aaggcgcgca tccgccggag ttgtttcgcg agcttgaaat 2160 tgccgagctg gatcaattga ttgccgtttc tcagcacacc ttacgcgtgg tagcgctggc 2220 accggaaaaa gagggggcat tgcaggccat ccgccatctt aaacagcaaa atgtacgagt 2280 gatgctgggg catagcgcgg cgacc 2305 <210> 1585 <211> 293 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(394..1272) <400> 1585 Met Ala Ser Asn Gln Thr Thr Leu Pro Asn Val Ser Glu Asn Glu Glu 1 5 10 15 Thr Leu Leu Thr Gly Val Asn Glu Asn Val Tyr Glu Asp Gln Ser Ile 20 25 30 Gly Ala Glu Leu Thr Lys Lys Asp Ile Asn Arg Val Ala Trp Arg Ser 35 40 45 Met Leu Leu Gln Ala Ser Phe Asn Tyr Glu Arg Met Gln Ala Ser Gly 50 55 60 Trp Leu Tyr Gly Leu Leu Pro Ala Leu Lys Lys Ile His Thr Asn Lys 65 70 75 80 Arg Asp Leu Ala Arg Ala Met Lys Gly His Met Gly Phe Phe Asn Thr 85 90 95 His Pro Phe Leu Val Thr Phe Val Ile Gly Ile Ile Leu Ala Met Glu 100 105 110 Arg Ser Lys Gln Asp Val Asn Ser Ile Gln Ser Thr Lys Ile Ala Val 115 120 125 Gly Ala Pro Leu Gly Gly Ile Gly Asp Ala Met Phe Trp Leu Thr Leu 130 135 140 Leu Pro Ile Cys Gly Gly Ile Gly Ala Ser Leu Ala Leu Gln Gly Ser 145 150 155 160 Ile Leu Gly Ala Val Val Phe Ile Val Leu Phe Asn Val Val His Leu 165 170 175 Gly Leu Arg Phe Gly Leu Ala His Tyr Ala Tyr Arg Met Gly Val Ala 180 185 190 Ala Ile Pro Leu Ile Lys Ala Asn Thr Lys Lys Val Gly His Ala Ala 195 200 205 Ser Ile Val Gly Met Thr Val Ile Gly Ala Leu Val Ala Thr Tyr Val 210 215 220 Arg Leu Ser Thr Thr Leu Glu Ile Thr Ala Gly Asp Ala Val Val Lys 225 230 235 240 Leu Gln Ala Asp Val Ile Asp Lys Leu Met Pro Ala Phe Leu Pro Leu 245 250 255 Val Tyr Thr Leu Thr Met Phe Trp Leu Val Arg Arg Gly Trp Ser Pro 260 265 270 Leu Arg Leu Ile Ala Val Thr Val Val Leu Gly Ile Val Gly Lys Phe 275 280 285 Cys His Phe Leu * 290 <210> 1586 <211> 145 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1290..1724) <400> 1586 Met Leu Ser Ile Ile Leu Thr Gly His Gly Gly Phe Ala Ser Gly Met 1 5 10 15 Glu Lys Ala Met Lys Gln Ile Leu Gly Glu Gln Ser Gln Phe Ile Ala 20 25 30 Ile Asp Phe Pro Glu Thr Ser Ser Thr Ala Leu Leu Thr Ser Gln Leu 35 40 45 Glu Glu Ala Ile Ala Gln Leu Asp Cys Glu Asp Gly Ile Val Phe Leu 50 55 60 Thr Asp Leu Leu Gly Gly Thr Pro Phe Arg Val Ala Ser Thr Leu Ala 65 70 75 80 Met Gln Lys Pro Gly Cys Glu Val Ile Thr Gly Thr Asn Leu Gln Leu 85 90 95 Leu Leu Glu Met Val Leu Glu Arg Glu Gly Leu Ser Gly Glu Glu Phe 100 105 110 Arg Val Gln Ala Leu Glu Cys Gly His Arg Gly Leu Thr Ser Leu Val 115 120 125 Asp Glu Leu Gly Arg Cys His Glu Glu Cys Pro Val Glu Glu Gly Ile 130 135 140 * <210> 1587 <211> 2292 <212> DNA <213> Escherichia coli O157:H7 <400> 1587 aatctctata ttttgtgcca gcttagggga agaggcttgc agatgcaagc tcgcctccat 60 tcattacgtc ttcactgtgt accccatatc agtaatgaaa aagaaacaat tcacacccat 120 cattcaggtg gtaaaaactg tagactatct taattagcta atttatatta tttatctaaa 180 tttgataggt gagataaaaa tgacagaaac ccagatctac gagaacatta agcaagccat 240 tagcagcgca ccacgaaata gccaaacgat ggaaatgcac ctccagatga tcaaatacgc 300 tgaccatctg aaaaacgtca cggcaaaaga gttttgcgaa ggtgtaggac ttaaagccag 360 ctttgctaca gagttcagca aaatgagaaa tcttaccgag cgactcaaag ccgccggact 420 tgataccacg aagttataac aaacgaaatc atcaatatat tactttcgtt ttccagggtt 480 ccctgtatat gtacctatga tcataaaaac cagttaccac cacgtagctg ataccataat 540 attttcattt ttactttaaa taaatagata aatttagaga gtggaataat taaggtctat 600 tttctctagc tttttgagat tgatagttga gaatgataat tctttcatct caataacacc 660 gaagtttgat agctgtttaa gccacagttg aagaccagca tcagagcaac ctgctcgata 720 tgttacatca ctacatttta ttagtgttga tttcctctta tagagataaa taaggacttc 780 atagatgcgt tttccggtgt cattggatac gcgctatacc cccattcttg gctaaatctt 840 ggttcataat catactttaa ttaaaatgga tctaaaaatt catcatagat ggctggattt 900 ttcatagaaa aatatgtttg aacaccattt gatattttta tttattgatc acaggctaac 960 gttcttgaat attctataaa tgatgcttcc tctattctaa ctctacccac gcaatatata 1020 tacaacccta cctatactcg aagtacgttc aacacataag acaacgaaaa gtagttgtgt 1080 gctgtaaaat ttaaatattt taataattaa tttcaagagc atgctgtgcc ccctatatta 1140 tgcaaatgaa aagtaggaaa aaatcataag acacattaaa cgattacaat aatcaaacct 1200 atattaaggt gaatagaagg tattcgaatg agtcatttct aatattttta gtcttacggg 1260 caaaggctat ctattaccta acatgcaatg gaaagcggaa aagtatgtag atagtgcaac 1320 ttgttccctg aactgctgtt tatccaacct attgctatga aaatacgtaa taatttcaaa 1380 cctaaacaat accattgcta aacaaatgaa aacttgttcg ttttactaat taatagtttt 1440 ataatgacta ccccaaaata ggtaacccaa atccaagcaa agggaaaata tgaagagtaa 1500 aatttttgct gcacttctgc tactacctct atctacttat gcaagctcct ataaatgtga 1560 tgctcttcag cagggtcaaa ttggcagcaa tgggaaaacc gttacggcac aatcctccat 1620 cgatattgac ggcaaacaga tgcattttag cttgaacgga gtgagttggg atctctcata 1680 tattggtgaa aaacagattg caaagatgta tagcaccgaa agcgggaacg tctctgtatc 1740 tttcattgat gccaatccca tcatcttcgt gctacatctc gtaaacgatg atggtagaaa 1800 aggcacttac aacatcagtg aatgttctga attataagag gctaaaatga aaaaactact 1860 cgttaccgtc atctttgtgg caatgatgcc aaatgcattc gcactaagtc acggagacag 1920 cgcaacactt aaagaaggta catttaactg taaaaagtta actgactttt acgagatgat 1980 cagttacatc caggacaatg accaacaggc tatgctgagt ctcattacat ccaataaatg 2040 tcgcgtgtta gatgaatcaa tgacggtaga aatccagagc gtagatgaca aaggttttgt 2100 ttcattcata actccaggtg gtcatggtgg ctgggctgtg aagcaatttt tcgaaaatta 2160 atcaaactat aacctcgaat ggcgtgtgtc ctcacgccat ttactctaat tcagcttaac 2220 gtcacttgtc cctctattta ttgcctcaac tacggccata ttaggcactt tcatttgata 2280 taagaatcca gc 2292 <210> 1588 <211> 80 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(200..439) <400> 1588 Met Thr Glu Thr Gln Ile Tyr Glu Asn Ile Lys Gln Ala Ile Ser Ser 1 5 10 15 Ala Pro Arg Asn Ser Gln Thr Met Glu Met His Leu Gln Met Ile Lys 20 25 30 Tyr Ala Asp His Leu Lys Asn Val Thr Ala Lys Glu Phe Cys Glu Gly 35 40 45 Val Gly Leu Lys Ala Ser Phe Ala Thr Glu Phe Ser Lys Met Arg Asn 50 55 60 Leu Thr Glu Arg Leu Lys Ala Ala Gly Leu Asp Thr Thr Lys Leu * 65 70 75 <210> 1589 <211> 116 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1490..1837) <400> 1589 Met Lys Ser Lys Ile Phe Ala Ala Leu Leu Leu Leu Pro Leu Ser Thr 1 5 10 15 Tyr Ala Ser Ser Tyr Lys Cys Asp Ala Leu Gln Gln Gly Gln Ile Gly 20 25 30 Ser Asn Gly Lys Thr Val Thr Ala Gln Ser Ser Ile Asp Ile Asp Gly 35 40 45 Lys Gln Met His Phe Ser Leu Asn Gly Val Ser Trp Asp Leu Ser Tyr 50 55 60 Ile Gly Glu Lys Gln Ile Ala Lys Met Tyr Ser Thr Glu Ser Gly Asn 65 70 75 80 Val Ser Val Ser Phe Ile Asp Ala Asn Pro Ile Ile Phe Val Leu His 85 90 95 Leu Val Asn Asp Asp Gly Arg Lys Gly Thr Tyr Asn Ile Ser Glu Cys 100 105 110 Ser Glu Leu * 115 <210> 1590 <211> 105 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1847..2161) <400> 1590 Met Lys Lys Leu Leu Val Thr Val Ile Phe Val Ala Met Met Pro Asn 1 5 10 15 Ala Phe Ala Leu Ser His Gly Asp Ser Ala Thr Leu Lys Glu Gly Thr 20 25 30 Phe Asn Cys Lys Lys Leu Thr Asp Phe Tyr Glu Met Ile Ser Tyr Ile 35 40 45 Gln Asp Asn Asp Gln Gln Ala Met Leu Ser Leu Ile Thr Ser Asn Lys 50 55 60 Cys Arg Val Leu Asp Glu Ser Met Thr Val Glu Ile Gln Ser Val Asp 65 70 75 80 Asp Lys Gly Phe Val Ser Phe Ile Thr Pro Gly Gly His Gly Gly Trp 85 90 95 Ala Val Lys Gln Phe Phe Glu Asn * 100 <210> 1591 <211> 2238 <212> DNA <213> Escherichia coli O157:H7 <400> 1591 tatgttcgtc gcggataaac aggatttctc tataacctcc ataaggaagt ggttattatt 60 gcgaaatcat cgtttcacgg aaagacgtca gaatgaaagc tacagaagct cgcctactcg 120 attttttaaa acgttcgcag cagtttgtta ttcccattta tcaacggact tattcatgga 180 cagaacaaca atgtcggcaa ctttgggacg acatcattcg tgcaggaaag cgtgacgata 240 tatcagcgca ttttatcggt tcggttgttt atatagagca gggattgtat caggtttctg 300 gtatttctcc gttgctggtc attgatggtc agcagcggct gacgaccgca atgttgctga 360 ttgaggcttt atcgcgccat cttggcgaag acgaagtttt tgatggcttt tcggcaatga 420 aattgcgtaa ttattatttg ctcaatcctt atgagtccgg cgagaaaggt tttaaattac 480 tgctgaccga gactgataaa gacagtttac tggcgttaat aaaacaaaga ccaatgccag 540 aaaactattc ccatcgaata atggaaaact ttactttctt tgatgaacaa attgccaaac 600 tcggtgatga cttgatcccc ttatgtcgtg ggttagcaaa gttattaatt gtcgatgtgg 660 cgcttaatcg tggtcaggat aatccgcaac tgatttttga aagtatgaac tccaccggta 720 aggcgttaag tcaggccgat ctggtgcgca attttattct gatgggcctc gaaccagagc 780 atcaaacccg gttgtatgaa gatcactggc gtccaatgga agtcgcttgt ggtcagcaag 840 gttacagcga atattttgac agttttatgc gtcattatct gacggtaaaa acggggagat 900 ccctcggaca gatgaagtct atgaggcatt taaactccat gcccgcagcc agagtgttgc 960 tgaaaaaggc gtagatcggc tggttgaaga tattcatatc tacgcggagt attactgtgc 1020 aatggcattg ggaaaagaaa gtgacaaatc gcttgctacg gcttttcagg atttgcgcga 1080 gttaaaggtt gatgtggcgt atcctttctt actggcgctt tatcatgact ataaaaatga 1140 cgatttgtct cacgaagatt tcctgagcat aattcgttta attgaatctt atgttttccg 1200 ccgtgcagta tgtgcgattc cgacaaattc tcttaacaag acgtttgcta ctttttataa 1260 ggtcattaat aaagaaaaat atctggaaag tattcaggta cattttttga atctaccttc 1320 atatcgtcgt ttccccaacg atgatgaatt taaacgggaa ttaaaagttc gcgatctcta 1380 taacttccgt agtcgtagct actggttacg acgactggaa aacgataaac gcagagagcg 1440 cgtggaagag tttacgattg aacatattat gccgcagaac gaaaatttgt cggctaaatg 1500 gcgcgaagag ctgggaagtg actggcagcg tattcataaa gaactgttgc atacgttggg 1560 gaatctcact ttaacgcgct ataactcccg ttacagtgac agacctttcg cagaaaaacg 1620 cgatattgaa gacggcttta agcatagccc gctctatttg aatatcggtc ttggacagtg 1680 cgaaaaatgg gatgaagctg ccattcacgc ccgagccgat cgtctggcgg agcttgcggt 1740 tcaggtctgg caagcgcctt ctcttcctga agaggtttta gctgtttatc ggggacagcc 1800 tgagaacaaa accagttaca gcctgagtga ttatcctttt cttgctgatg gttcgcatag 1860 ccgggtgtta ttcgatcatc ttcgcgatga aattatgcgc ctggacgcag ggatcacgca 1920 ggaagtattg aagctctata ttgcgtttaa agcggaaacg aattttgttg atgttgtgcc 1980 gcaaaaaagc cgactgcgat tgtcgcttaa tatgcagttt catgaactgg tcgatccgaa 2040 aggtattgcc aaagatgtga caaatgttgg gcgatggggc aatggtgatg tggaaattgg 2100 tttcagtgac ctcgcacaac ttccttacat tatggggtta attcgtcagg catttgaaaa 2160 acagatggag agcgcgttgg tataacgcag cgaaaaatgc ccggtagtcc tggcgctacc 2220 gggtcaatgt atcaggca 2238 <210> 1592 <211> 294 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(93..974) <400> 1592 Met Lys Ala Thr Glu Ala Arg Leu Leu Asp Phe Leu Lys Arg Ser Gln 1 5 10 15 Gln Phe Val Ile Pro Ile Tyr Gln Arg Thr Tyr Ser Trp Thr Glu Gln 20 25 30 Gln Cys Arg Gln Leu Trp Asp Asp Ile Ile Arg Ala Gly Lys Arg Asp 35 40 45 Asp Ile Ser Ala His Phe Ile Gly Ser Val Val Tyr Ile Glu Gln Gly 50 55 60 Leu Tyr Gln Val Ser Gly Ile Ser Pro Leu Leu Val Ile Asp Gly Gln 65 70 75 80 Gln Arg Leu Thr Thr Ala Met Leu Leu Ile Glu Ala Leu Ser Arg His 85 90 95 Leu Gly Glu Asp Glu Val Phe Asp Gly Phe Ser Ala Met Lys Leu Arg 100 105 110 Asn Tyr Tyr Leu Leu Asn Pro Tyr Glu Ser Gly Glu Lys Gly Phe Lys 115 120 125 Leu Leu Leu Thr Glu Thr Asp Lys Asp Ser Leu Leu Ala Leu Ile Lys 130 135 140 Gln Arg Pro Met Pro Glu Asn Tyr Ser His Arg Ile Met Glu Asn Phe 145 150 155 160 Thr Phe Phe Asp Glu Gln Ile Ala Lys Leu Gly Asp Asp Leu Ile Pro 165 170 175 Leu Cys Arg Gly Leu Ala Lys Leu Leu Ile Val Asp Val Ala Leu Asn 180 185 190 Arg Gly Gln Asp Asn Pro Gln Leu Ile Phe Glu Ser Met Asn Ser Thr 195 200 205 Gly Lys Ala Leu Ser Gln Ala Asp Leu Val Arg Asn Phe Ile Leu Met 210 215 220 Gly Leu Glu Pro Glu His Gln Thr Arg Leu Tyr Glu Asp His Trp Arg 225 230 235 240 Pro Met Glu Val Ala Cys Gly Gln Gln Gly Tyr Ser Glu Tyr Phe Asp 245 250 255 Ser Phe Met Arg His Tyr Leu Thr Val Lys Thr Gly Arg Ser Leu Gly 260 265 270 Gln Met Lys Ser Met Arg His Leu Asn Ser Met Pro Ala Ala Arg Val 275 280 285 Leu Leu Lys Lys Ala * 290 <210> 1593 <211> 388 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1022..2185) ＜４００＞ １５９３ Ｍｅｔ Ａｌａ Ｌｅｕ Ｇｌｙ Ｌｙｓ Ｇｌｕ Ｓｅｒ Ａｓｐ Ｌｙｓ
Ｓｅｒ Ｌｅｕ Ａｌａ Ｔｈｒ Ａｌａ Ｐｈｅ Ｇｌｎ １ ５
１０ １５ Ａｓｐ Ｌｅｕ Ａｒｇ Ｇｌｕ Ｌｅｕ Ｌｙｓ Ｖａｌ Ａｓｐ Ｖａｌ
Ａｌａ Ｔｙｒ Ｐｒｏ Ｐｈｅ Ｌｅｕ Ｌｅｕ Ａｌａ ２０ ２５
３０ Ｌｅｕ Ｔｙｒ Ｈｉｓ Ａｓｐ Ｔｙｒ Ｌｙｓ Ａｓｎ Ａｓｐ Ａｓｐ
Ｌｅｕ Ｓｅｒ Ｈｉｓ Ｇｌｕ Ａｓｐ Ｐｈｅ Ｌｅｕ ３５ ４０
４５ Ｓｅｒ Ｉｌｅ Ｉｌｅ Ａｒｇ Ｌｅｕ Ｉｌｅ Ｇｌｕ Ｓｅｒ Ｔｙｒ
Ｖａｌ Ｐｈｅ Ａｒｇ Ａｒｇ Ａｌａ Ｖａｌ Ｃｙｓ ５０ ５５
６０ Ａｌａ Ｉｌｅ Ｐｒｏ Ｔｈｒ Ａｓｎ Ｓｅｒ Ｌｅｕ Ａｓｎ Ｌｙｓ
Ｔｈｒ Ｐｈｅ Ａｌａ Ｔｈｒ Ｐｈｅ Ｔｙｒ Ｌｙｓ ６５ ７０
７５ ８０ Ｖａｌ Ｉｌｅ Ａｓｎ Ｌｙｓ Ｇｌｕ Ｌｙｓ Ｔｙｒ Ｌｅｕ Ｇｌｕ
Ｓｅｒ Ｉｌｅ Ｇｌｎ Ｖａｌ Ｈｉｓ Ｐｈｅ Ｌｅｕ ８５
９０ ９５ Ａｓｎ Ｌｅｕ Ｐｒｏ Ｓｅｒ Ｔｙｒ Ａｒｇ Ａｒｇ Ｐｈｅ Ｐｒｏ
Ａｓｎ Ａｓｐ Ａｓｐ Ｇｌｕ Ｐｈｅ Ｌｙｓ Ａｒｇ １００ １０５
１１０ Ｇｌｕ Ｌｅｕ Ｌｙｓ Ｖａｌ Ａｒｇ Ａｓｐ Ｌｅｕ Ｔｙｒ Ａｓｎ
Ｐｈｅ Ａｒｇ Ｓｅｒ Ａｒｇ Ｓｅｒ Ｔｙｒ Ｔｒｐ １１５ １２０
１２５ Ｌｅｕ Ａｒｇ Ａｒｇ Ｌｅｕ Ｇｌｕ Ａｓｎ Ａｓｐ Ｌｙｓ Ａｒｇ
Ａｒｇ Ｇｌｕ Ａｒｇ Ｖａｌ Ｇｌｕ Ｇｌｕ Ｐｈｅ １３０ １３５
１４０ Ｔｈｒ Ｉｌｅ Ｇｌｕ Ｈｉｓ Ｉｌｅ Ｍｅｔ Ｐｒｏ Ｇｌｎ Ａｓｎ
Ｇｌｕ Ａｓｎ Ｌｅｕ Ｓｅｒ Ａｌａ Ｌｙｓ Ｔｒｐ １４５ １５０
１５５ １６０ Ａｒｇ Ｇｌｕ Ｇｌｕ Ｌｅｕ Ｇｌｙ Ｓｅｒ Ａｓｐ Ｔｒｐ Ｇｌｎ
Ａｒｇ Ｉｌｅ Ｈｉｓ Ｌｙｓ Ｇｌｕ Ｌｅｕ Ｌｅｕ １６５
１７０ １７５ Ｈｉｓ Ｔｈｒ Ｌｅｕ Ｇｌｙ Ａｓｎ Ｌｅｕ Ｔｈｒ Ｌｅｕ Ｔｈｒ
Ａｒｇ Ｔｙｒ Ａｓｎ Ｓｅｒ Ａｒｇ Ｔｙｒ Ｓｅｒ １８０ １８５
１９０ Ａｓｐ Ａｒｇ Ｐｒｏ Ｐｈｅ Ａｌａ Ｇｌｕ Ｌｙｓ Ａｒｇ Ａｓｐ
Ｉｌｅ Ｇｌｕ Ａｓｐ Ｇｌｙ Ｐｈｅ Ｌｙｓ Ｈｉｓ １９５ ２００
２０５ Ｓｅｒ Ｐｒｏ Ｌｅｕ Ｔｙｒ Ｌｅｕ Ａｓｎ Ｉｌｅ Ｇｌｙ Ｌｅｕ
Ｇｌｙ Ｇｌｎ Ｃｙｓ Ｇｌｕ Ｌｙｓ Ｔｒｐ Ａｓｐ Glu Ala Ala Ile His Ala Arg Ala Asp Arg Leu Ala Glu Leu Ala Val 225 230 235 240 Gln Val Trp Gln Ala Pro Ser Leu Pro Glu Glu Val Leu Ala Val Tyr 245 250 255 Arg Gly Gln Pro Glu Asn Lys Thr Ser Tyr Ser Leu Ser Asp Tyr Pro 260 265 270 Phe Leu Ala Asp Gly Ser His Ser Arg Val Leu Phe Asp His Leu Arg 275 280 285 Asp Glu Ile Met Arg Leu Asp Ala Gly Ile Thr Gln Glu Val Leu Lys 290 295 300 Leu Tyr Ile Ala Phe Lys Ala Glu Thr Asn Phe Val Asp Val Val Pro 305 310 315 320 Gln Lys Ser Arg Leu Arg Leu Ser Leu Asn Met Gln Phe His Glu Leu 325 330 335 Val Asp Pro Lys Gly Ile Ala Lys Asp Val Thr Asn Val Gly Arg Trp 340 345 350 Gly Asn Gly Asp Val Glu Ile Gly Phe Ser Asp Leu Ala Gln Leu Pro 355 360 365 Tyr Ile Met Gly Leu Ile Arg Gln Ala Phe Glu Lys Gln Met Glu Ser 370 375 380 Ala Leu Val * 385 <210> 1594 <211> 2174 <212> DNA <213> Escherichia coli O157:H7 <400> 1594 gcctggtgat gtggatgccg gaaacattga cggcagcatc catcgctggg caaaaaatga 60 agttatcgac aacggccgcg aagactggaa gcgtatctcg gcatcaatgc gcaaacagcc 120 tgatgccctt cgctacgacc gccagactat ttttggcctt gtccgtgaac gtccgatcga 180 cattcacaaa gaccctgtgg cactgaacaa atacattact gaatacctga ctacaaaggg 240 cgtgtttgaa gatgaaggaa caaatcagag cgcaactgat actctctcgt cgccagtacc 300 agaaactgat gcagtggaaa cggcaattcc agacaacgaa aaaaccgaat gcaaagtgga 360 agtcgaacca tctgtagaac gtgaggggcc gttctacttc ctcttcaccg acaaggatgg 420 cgaaaaatac ggtcgcgcaa acaaactttc tggtctggat aaggcgctgg ctgccggggc 480 tactgaaatc acaaaagaag aatattttgc ccgaaaaaat ggcacataca caggcttacc 540 gcaaaatgca aataccgcac aaaattctga acaaccagaa ccggtaaaag ttaccgctga 600 cgaagtaaag aaaattatgc aggcagccaa tatcagccag cctgacgccg aggaactgct 660 tgcagtatca cgtggtgaat ttgttgaagg gattagcgac ccgaatgatc cgaaatgggt 720 taaggggatc cagacccgcg attctgtgaa ccagaaccag caagaaacgg aacagaacga 780 ccagaaagcg gaacaaaaca gcccaaatac gcaacaaaac gagccagaaa cgaaacaacc 840 tgaaccagta gtgcaacagg aaccggaaaa gatctgcacc gcctgcggtc agagcggtgg 900 cggcaactgc cctgattgtg gtgcggtgat gggtgacgca acataccagg aaatattcga 960 tggagagaat cagcctgaag ttcaggaaaa tgatccggag gaaatggaag gtactgcaca 1020 tcagcacaag gagaacactg gcggcaatca gcatcatgcc agcgatagtg aaactggcga 1080 ggcgtcagat cccttaatta aggcgaacgg tcatcataat ctcacatcca ccagcagagc 1140 ggggattcat ctgatgatcg atcttgaaac catgggaaaa aatcccgatg ccccgattat 1200 ctcaataggt gcaatatttt tcgatccgca aaccggagat atgggaccgg aatttagtaa 1260 gactatcgat ctggatactg ctggcggagt cattgatcgg gacaccatga aatggtggct 1320 taaacaatca cgcgaagcgc aatctgccat tatgaccgat gaaatcccgt tagatgatgc 1380 actgttacaa ttgcgggaat ttatcgacga aaactccggt gaattttttg ttcatgtctg 1440 gggaaatgga gccaacttcg acaacacgat tttgcgccgt tcatacgaac ggcaggggag 1500 cccctgcccg tggcgttact acaacgatcg cgatgtacgc acaatcgttg agctggggaa 1560 agccatagac ttcgatgcca gaacggctat tccattcgaa ggtgagcgcc ataatgcact 1620 tgatgacgcc cgttaccagg caaaatacgt ttcagctatc tggcaaaaac tgatcccgag 1680 tcaggctgat tcttaatgtt caactgtcgc cggttgtgac tggtattctg caaccggcgc 1740 tcgtctgatg taagagataa agaaatcgat gagcgaagta atcatgattg tctctcccgg 1800 caaatgggta tccgaagagc agttaattgc gctgaaagga ataaaaaaag gtacgttaaa 1860 aaaggcccgg gaaaaatcgt ttatggaagg aagggaatat aagcatgtcg ctcatgacgg 1920 tatgccatgg gataacagtc catgctttta caacctggaa gaaattgatc gctggattga 1980 gcgccaggca tcagcaagac caagacgtca tcttacttga ctaaaagcca cactaactaa 2040 tgagagaagt tgaaatgaaa tatccgacag gcgtggaaaa ccatggaggg aaattacgta 2100 tctggtttgt ttataaaggc gtaagagtca gggaaaacct ggggttcctg acacagcaaa 2160 aaacaggcgc gttg 2174 <210> 1595 <211> 84 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1769..2020) <400> 1595 Met Ser Glu Val Ile Met Ile Val Ser Pro Gly Lys Trp Val Ser Glu 1 5 10 15 Glu Gln Leu Ile Ala Leu Lys Gly Ile Lys Lys Gly Thr Leu Lys Lys 20 25 30 Ala Arg Glu Lys Ser Phe Met Glu Gly Arg Glu Tyr Lys His Val Ala 35 40 45 His Asp Gly Met Pro Trp Asp Asn Ser Pro Cys Phe Tyr Asn Leu Glu 50 55 60 Glu Ile Asp Arg Trp Ile Glu Arg Gln Ala Ser Ala Arg Pro Arg Arg 65 70 75 80 His Leu Thr * <210> 1596 <211> 2082 <212> DNA <213> Escherichia coli O157:H7 <400> 1596 gcagtagtct gacttctgaa aagtactcag tgcgtcaacg ccttgtccgc ctacaggcct 60 gaaaaacata gcgcatcagg ggattttgcc ctggtcacca gtcttatagg accccgaagc 120 ctggcttcgg ggttattaat ttaaagcact gcgcaattgc tgtgctacct gtcgcgccat 180 actttcgcta acgatattcg taaacgagag caataatcct ccgtcctcgc ttgagcggat 240 acgccagtcg ctaagtgcct gtacggcaag accagcagca ttggctttat gcacgaatgt 300 cacgtcatta cctgctagtt tgatcaccat ctggataccg cctttttgcg gcacaacctg 360 aaatccctgc tgcgtaagtg cctgctcaat ccactgccgt cgctgggcat aatgctggcg 420 cattttcttc agatgccgcc agaaatgccc ctcacggatg aaatctgcca gtgtgttctg 480 ccacagtacg ggtacagcac atggttccag tgacgcctgc tgccggaatt gcgaaatctg 540 ctccaccggc accaccagcc acgcacagcg caatgcagga aatagcgctt tgctgaatgt 600 tccggcataa atcacccgct gcggcgcgtc gagacttttt agtgccggta acggcttacc 660 gtgatagcga aactcactgt cgtaatcatc ttcaataatc catgcctgac tacgctctgc 720 ccattccagt atctgatacc tacgcgctaa agagagtgcc acacccagcg ggctttggtg 780 tgccggagta atcagggcaa aacgcgcatc aggataattt tgtattccgc ttgtgacatc 840 cagtccgttg tcatcaaccg gcacaggtaa aatttccaca ccgtggcgag tgacaatcgg 900 gcgaatcagc ggaaagccgg gatcttccat ccacatcccg tctcccggtt gcgccagagc 960 gtgcagaatt aaagccattg aggccgcata accgtgagtg ataaagacct gctctggctg 1020 acaatcaatc ccacgtgaaa cgcgtaaata atcaacaata gcctcgcgca aggccgcctc 1080 gccgcagaca tcgcctaatg ccaaatcaaa gcgcgtctgg gtacgcagac ggcggcccat 1140 cacccgcgcc cacaattcac gcggaaaaag atcaagtgca ggtagcccca tctgaaaagg 1200 cagcggctgc tgactttcac cagcaaaagc cacgacatcc acagcagact gttgcggatg 1260 tatctgctca ctgacaaagg tacccgcctg tccccgcctg accagccatc cctgcgccac 1320 cagctcagca taagcatttt cgacagtgga tcgagagaca cccagctcct gcgaccaggt 1380 acggctcgaa ggtagccttg cgccaggttt cagttttcct tgctcgataa ccgtttttaa 1440 ctgacgggcg atatcctgat aacgtggcat atggtctgct tttttaggta atttatggct 1500 ctctttagca gtccattata gtgctacatt gcgggcgtta ataagaggag aaactgtatg 1560 actacattac gtcagcctta ctacgaactt agcccggcag tgtataacgc actggtgcag 1620 gccaaaacgg cactggaaaa tagcacgctg gataccacgt tgatggagtt aatttatttg 1680 cgcgtctcgc aaatcaacgg ctgcgcattt tgtctggaga tgcacagcaa agcattgcgc 1740 aaatccggtg tgccacaaca caaactggac gccctggcag gctggcgcgt aagccatcat 1800 tttgatgaac gcgagcgagc ggcgctggca tgggcggaat ctgtgaccga tattgccaga 1860 acccatgcgg aagacgaggt ttatcagcct ttgcttgagc atttcagcgc agcagaaatc 1920 agcgacttaa cgtttgccat cgggctgatg aattgtttta accgtctggc cgtttccatg 1980 cggatgtaat ttgctgttgc cgggtatgcg cccggcaaaa aaacacaaaa tcccctaccc 2040 cgttgagcca ttcaccggtg gcgtaatcaa tctaaaatta cc 2082 <210> 1597 <211> 445 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(136..1470) <400> 1597 Met Pro Arg Tyr Gln Asp Ile Ala Arg Gln Leu Lys Thr Val Ile Glu 1 5 10 15 Gln Gly Lys Leu Lys Pro Gly Ala Arg Leu Pro Ser Ser Arg Thr Trp 20 25 30 Ser Gln Glu Leu Gly Val Ser Arg Ser Thr Val Glu Asn Ala Tyr Ala 35 40 45 Glu Leu Val Ala Gln Gly Trp Leu Val Arg Arg Gly Gln Ala Gly Thr 50 55 60 Phe Val Ser Glu Gln Ile His Pro Gln Gln Ser Ala Val Asp Val Val 65 70 75 80 Ala Phe Ala Gly Glu Ser Gln Gln Pro Leu Pro Phe Gln Met Gly Leu 85 90 95 Pro Ala Leu Asp Leu Phe Pro Arg Glu Leu Trp Ala Arg Val Met Gly 100 105 110 Arg Arg Leu Arg Thr Gln Thr Arg Phe Asp Leu Ala Leu Gly Asp Val 115 120 125 Cys Gly Glu Ala Ala Leu Arg Glu Ala Ile Val Asp Tyr Leu Arg Val 130 135 140 Ser Arg Gly Ile Asp Cys Gln Pro Glu Gln Val Phe Ile Thr His Gly 145 150 155 160 Tyr Ala Ala Ser Met Ala Leu Ile Leu His Ala Leu Ala Gln Pro Gly 165 170 175 Asp Gly Met Trp Met Glu Asp Pro Gly Phe Pro Leu Ile Arg Pro Ile 180 185 190 Val Thr Arg His Gly Val Glu Ile Leu Pro Val Pro Val Asp Asp Asn 195 200 205 Gly Leu Asp Val Thr Ser Gly Ile Gln Asn Tyr Pro Asp Ala Arg Phe 210 215 220 Ala Leu Ile Thr Pro Ala His Gln Ser Pro Leu Gly Val Ala Leu Ser 225 230 235 240 Leu Ala Arg Arg Tyr Gln Ile Leu Glu Trp Ala Glu Arg Ser Gln Ala 245 250 255 Trp Ile Ile Glu Asp Asp Tyr Asp Ser Glu Phe Arg Tyr His Gly Lys 260 265 270 Pro Leu Pro Ala Leu Lys Ser Leu Asp Ala Pro Gln Arg Val Ile Tyr 275 280 285 Ala Gly Thr Phe Ser Lys Ala Leu Phe Pro Ala Leu Arg Cys Ala Trp 290 295 300 Leu Val Val Pro Val Glu Gln Ile Ser Gln Phe Arg Gln Gln Ala Ser 305 310 315 320 Leu Glu Pro Cys Ala Val Pro Val Leu Trp Gln Asn Thr Leu Ala Asp 325 330 335 Phe Ile Arg Glu Gly His Phe Trp Arg His Leu Lys Lys Met Arg Gln 340 345 350 His Tyr Ala Gln Arg Arg Gln Trp Ile Glu Gln Ala Leu Thr Gln Gln 355 360 365 Gly Phe Gln Val Val Pro Gln Lys Gly Gly Ile Gln Met Val Ile Lys 370 375 380 Leu Ala Gly Asn Asp Val Thr Phe Val His Lys Ala Asn Ala Ala Gly 385 390 395 400 Leu Ala Val Gln Ala Leu Ser Asp Trp Arg Ile Arg Ser Ser Glu Asp 405 410 415 Gly Gly Leu Leu Leu Ser Phe Thr Asn Ile Val Ser Glu Ser Met Ala 420 425 430 Arg Gln Val Ala Gln Gln Leu Arg Ser Ala Leu Asn * 435 440 <210> 1598 <211> 144 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1558..1989) <400> 1598 Met Thr Thr Leu Arg Gln Pro Tyr Tyr Glu Leu Ser Pro Ala Val Tyr 1 5 10 15 Asn Ala Leu Val Gln Ala Lys Thr Ala Leu Glu Asn Ser Thr Leu Asp 20 25 30 Thr Thr Leu Met Glu Leu Ile Tyr Leu Arg Val Ser Gln Ile Asn Gly 35 40 45 Cys Ala Phe Cys Leu Glu Met His Ser Lys Ala Leu Arg Lys Ser Gly 50 55 60 Val Pro Gln His Lys Leu Asp Ala Leu Ala Gly Trp Arg Val Ser His 65 70 75 80 His Phe Asp Glu Arg Glu Arg Ala Ala Leu Ala Trp Ala Glu Ser Val 85 90 95 Thr Asp Ile Ala Arg Thr His Ala Glu Asp Glu Val Tyr Gln Pro Leu 100 105 110 Leu Glu His Phe Ser Ala Ala Glu Ile Ser Asp Leu Thr Phe Ala Ile 115 120 125 Gly Leu Met Asn Cys Phe Asn Arg Leu Ala Val Ser Met Arg Met * 130 135 140 <210> 1599 <211> 2047 <212> DNA <213> Escherichia coli O157:H7 <400> 1599 aatgagtaat gaatcaccga agcaatcgct attaaatgat ttttcacatc gccttaaaat 60 ggaaggtgag gaacaactgt tccattgtgt taacgaactg aagtatggtt tgtcgagtaa 120 taatgaatat gacctgttta aaaatagaga aacctcactg tggaaacgca aagtaccaga 180 aagcgcagcg ctggcaatga cgggaacagt atataaatta tttggtagtc gcttactcaa 240 cgcccgcaat cagttagata aaaatctcct cgaaatggct atgcaaatgg tttatggcaa 300 agatatggtg acaaagtccg gggatatatt gattgatata caattaaata aggatggcag 360 cctccagagt aagcactaca catttgatgt aggtgaagtt ataaacagtt ataatattga 420 cctctttgtg aatgcttcga gtattaatca aacttactta catgataaaa atcctggtga 480 tgttattagc ctgtatggca ctttagataa cattcctctt gtagttaagg aatgcacggg 540 taaaaatcat caaattaacg ttaaagccaa attgccacaa gaacgaagtg aaaaagttga 600 ggatatgtgt gaaagaatga gaggtggcat ctctatgttt aatcacacca caaaaacagc 660 tggtaatata gagcataatt tgcagctaag ttttctcgtg gattcacggc cgtcgatcac 720 caataaatac tcagccaaag atgtagcgcc agacatactt gtattgcccg tcaacgtata 780 tcatgcggat tttaaaatta aaatcaataa tgcagtagag aagacttagt caattgtgtt 840 atgtgctgtg caaaaaaatc tccatgcagc aaggaaggtt cttagcggga taataggtaa 900 tgtaccaaaa aataataaac caaaaacaat catttttgat ttacgttttc ttagtgcaat 960 taagcagaaa gtttttttgg gcagtgaaca accgttgttt gtaaagcata ccgcaatgat 1020 gagggaggca tgtaaggaat taccgcagct agtggagtat gttcctttag cctgtgaagc 1080 gcatagccat cgcagcgtcg cccttgccaa aaccgtggct gcacccatca tggcgacagg 1140 tgtgggcgcg gctttaatgt atgcaacatc atcaggaccg tattatgcgc aaagtctttc 1200 tggttcgccg gatatcgaga tgataaaaaa acgcatggct gaattgttta accagtcgga 1260 tacttctgtg cgcaacaaat atcgcccggc ttttgataaa tggaataaac tggtagataa 1320 attaaatcac gaaagaaata cagttccgtt tgcgtgtttg accaccatta tagcgacagc 1380 gataaatgaa actcctgagg gggatacgaa tgttgccgtt gtgatggggt gtaaatctgc 1440 gaaagatcgc acgatatcca ttgtccttgg caactcgatg ttgcaaacac tctttgaaaa 1500 acgcctcgcc gatgatggag aaatagaaaa cctttttgat caacagggat attttagttg 1560 cgattcatta acagccgaag aagtaatgat gttaaaagac ctttttgata ttcgagttct 1620 tcatctctct aacaaattta atgttgggtt gcaaggtaat atcaacacgg atgttttaca 1680 agattcgttt tttaaaaatg tcgatttcat tcatgaatct aactcgtata ccgtagggat 1740 gggagtctga agagtaaaac tcattaggat tatcagaatt cggccaatgc attgcaaaaa 1800 tgaaatacaa agagagatgt gtgcaggcgc ttagccgcga ggggcatggc gaagccatac 1860 agaaagcacc ggcattcaga actcctgtga aagcggcata gtgccgctgc tcaggagttt 1920 tgttatgacc cgtatcgtgc tgaacgttgc caccctatga tgcgattaaa aaaactcacc 1980 gtcgagccga tgattgacgt caatgctatc ggatgatgcc gggggtgttc cggaaggaat 2040 tccttgt 2047 <210> 1600 <211> 305 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(836..1750) <400> 1600 Val Leu Cys Ala Val Gln Lys Asn Leu His Ala Ala Arg Lys Val Leu 1 5 10 15 Ser Gly Ile Ile Gly Asn Val Pro Lys Asn Asn Lys Pro Lys Thr Ile 20 25 30 Ile Phe Asp Leu Arg Phe Leu Ser Ala Ile Lys Gln Lys Val Phe Leu 35 40 45 Gly Ser Glu Gln Pro Leu Phe Val Lys His Thr Ala Met Met Arg Glu 50 55 60 Ala Cys Lys Glu Leu Pro Gln Leu Val Glu Tyr Val Pro Leu Ala Cys 65 70 75 80 Glu Ala His Ser His Arg Ser Val Ala Leu Ala Lys Thr Val Ala Ala 85 90 95 Pro Ile Met Ala Thr Gly Val Gly Ala Ala Leu Met Tyr Ala Thr Ser 100 105 110 Ｓｅｒ Ｇｌｙ Ｐｒｏ Ｔｙｒ Ｔｙｒ Ａｌａ Ｇｌｎ Ｓｅｒ Ｌｅｕ
Ｓｅｒ Ｇｌｙ Ｓｅｒ Ｐｒｏ Ａｓｐ Ｉｌｅ Ｇｌｕ １１５ １２０
１２５ Ｍｅｔ Ｉｌｅ Ｌｙｓ Ｌｙｓ Ａｒｇ Ｍｅｔ Ａｌａ Ｇｌｕ Ｌｅｕ
Ｐｈｅ Ａｓｎ Ｇｌｎ Ｓｅｒ Ａｓｐ Ｔｈｒ Ｓｅｒ １３０ １３５
１４０ Ｖａｌ Ａｒｇ Ａｓｎ Ｌｙｓ Ｔｙｒ Ａｒｇ Ｐｒｏ Ａｌａ Ｐｈｅ
Ａｓｐ Ｌｙｓ Ｔｒｐ Ａｓｎ Ｌｙｓ Ｌｅｕ Ｖａｌ １４５ １５０
１５５ １６０ Ａｓｐ Ｌｙｓ Ｌｅｕ Ａｓｎ Ｈｉｓ Ｇｌｕ Ａｒｇ Ａｓｎ Ｔｈｒ
Ｖａｌ Ｐｒｏ Ｐｈｅ Ａｌａ Ｃｙｓ Ｌｅｕ Ｔｈｒ １６５
１７０ １７５ Ｔｈｒ Ｉｌｅ Ｉｌｅ Ａｌａ Ｔｈｒ Ａｌａ Ｉｌｅ Ａｓｎ Ｇｌｕ
Ｔｈｒ Ｐｒｏ Ｇｌｕ Ｇｌｙ Ａｓｐ Ｔｈｒ Ａｓｎ １８０ １８５
１９０ Ｖａｌ Ａｌａ Ｖａｌ Ｖａｌ Ｍｅｔ Ｇｌｙ Ｃｙｓ Ｌｙｓ Ｓｅｒ
Ａｌａ Ｌｙｓ Ａｓｐ Ａｒｇ Ｔｈｒ Ｉｌｅ Ｓｅｒ １９５ ２００
２０５ Ｉｌｅ Ｖａｌ Ｌｅｕ Ｇｌｙ Ａｓｎ Ｓｅｒ Ｍｅｔ Ｌｅｕ Ｇｌｎ
Ｔｈｒ Ｌｅｕ Ｐｈｅ Ｇｌｕ Ｌｙｓ Ａｒｇ Ｌｅｕ ２１０ ２１５
２２０ Ａｌａ Ａｓｐ Ａｓｐ Ｇｌｙ Ｇｌｕ Ｉｌｅ Ｇｌｕ Ａｓｎ Ｌｅｕ
Ｐｈｅ Ａｓｐ Ｇｌｎ Ｇｌｎ Ｇｌｙ Ｔｙｒ Ｐｈｅ ２２５ ２３０
２３５ ２４０ Ｓｅｒ Ｃｙｓ Ａｓｐ Ｓｅｒ Ｌｅｕ Ｔｈｒ Ａｌａ Ｇｌｕ Ｇｌｕ
Ｖａｌ Ｍｅｔ Ｍｅｔ Ｌｅｕ Ｌｙｓ Ａｓｐ Ｌｅｕ ２４５
２５０ ２５５ Ｐｈｅ Ａｓｐ Ｉｌｅ Ａｒｇ Ｖａｌ Ｌｅｕ Ｈｉｓ Ｌｅｕ Ｓｅｒ
Ａｓｎ Ｌｙｓ Ｐｈｅ Ａｓｎ Ｖａｌ Ｇｌｙ Ｌｅｕ ２６０ ２６５
２７０ Ｇｌｎ Ｇｌｙ Ａｓｎ Ｉｌｅ Ａｓｎ Ｔｈｒ Ａｓｐ Ｖａｌ Ｌｅｕ
Ｇｌｎ Ａｓｐ Ｓｅｒ Ｐｈｅ Ｐｈｅ Ｌｙｓ Ａｓｎ ２７５ ２８０
２８５ Ｖａｌ Ａｓｐ Ｐｈｅ Ｉｌｅ Ｈｉｓ Ｇｌｕ Ｓｅｒ Ａｓｎ Ｓｅｒ
Ｔｙｒ Ｔｈｒ Ｖａｌ Ｇｌｙ Ｍｅｔ Ｇｌｙ Ｖａｌ ２９０ ２９５
３００ ＊ ＜２１０＞ １６０１ <212> DNA <213> Escherichia coli O157:H7 <400> 1601 ttaaatgcca ttgaccggga ggtgtaggcg attccagacc acccggtttg atttataaat 60 gaacagtgcc ccaattttgg ggcactctgt taaagtaaaa cccgacatcg ccgaatatac 120 tatgcggcga tatttcaagg tgtatctttg tcactcataa ttcaatgaca ctgaaatatc 180 gtcagtcgac gaactcataa taattgctca tattctctga ctgttgacga aaaatatcat 240 caaaattatt ctcaatggtt tcggtcatag tgttgaataa atttttagaa agttcatcta 300 ttttgtcttg aatctttgat tttatttcat cttgaatttc acgggtaacc aaaagttggt 360 ccaattgatc atccattttg tattttgcaa ttaattgtgc agttaaaggt actttcttca 420 aataatcatt ttttgttagt ttatactggt ctttgaaata ttgtttggct tctgcttgta 480 tatatttaaa aaattcatta tactttttcc tgcttatttt ttcttgaaga ttcattgcgc 540 gattgaatat tttctttaaa tgctgattgt agaaaataaa attatcgata tcttgtttta 600 ttttaataac tgttgatttt tcttcaaagt ttaatgactc agggttttta tctgattcaa 660 tatagtcaag aataattttt gctaatgggc taatgtcttt ttcttctgtt gattctgctt 720 ctgtttttaa tatcggatta aaaaggtcgg tacggtaaag tttcgtgcct ttcatcctga 780 cgatgtcagg aagaatagtg tttgaaagat tagcctcgct aaagtccaca ttttggcaat 840 cactttctga taaatctgcc caattgaaag tggttttcac acaggagcag ttagttagaa 900 tcatcccttt cgtttcattc ccatctgatt tctgataagt tatcctttgt attatttgat 960 ctgcttctgg atattgcatc tcaggttctt tttctttacc atatatcatc gcattatcaa 1020 gaattgcgcc agtgcaattc atatttgtca ggtcgcattt cttaaatcta caattgttaa 1080 aattcgcatt tgtacaattc gcatttgtaa acttgacgcc ataaaaataa gtatgttcga 1140 agttgacatt tgagcagtta cagtttccca tatctatacc gaaatctata tcgggatctt 1200 tattgggatc tttaccggaa atattgctgt gtgctagata tagaccgctg aaatcgtaat 1260 atccattgtc atccttttct attgggagtg aataagtctt tactacctcg ttaacaatag 1320 agatagttcc acgtatcatc agattttctc cgtctttata aaaaataatg ttatgtttga 1380 tggtactgtt gtatggctct ggcaatgagg atgcaatttt attccagaaa caacaaagcg 1440 tggtctgttt ttgtttgggc gagaggcgat caaaatccag ctttaaatat gagtctaaat 1500 ctgacgttgc atctatatta aagttgggat ctggagttaa cgctgaatta taatttagaa 1560 ctgacaatgt attgatgtat ttatgaatcg atttaaatgc cttttgttta tcactgtcca 1620 gaaaaaaatc acgaattttg ttccacagcc tttcaataag attttgattt aaatcttgct 1680 tcattgagtt tcttaaatct gcaaccggta catcagtaaa caggatcggt tgtttggtga 1740 tggttttcat catgattgta atcctcttac gttgactaaa taagacagtt ttaggggata 1800 ttacctggag aaactatcaa aaatcgctca aagggatgaa gacgatgaat agctgcaaac 1860 tcattcacga agaatttctc ttgcagaggt ggattatggt tacagaaggt gatgggaggt 1920 acgttgtccc catcatcgca gacgatgggg aattcagcag ataaaatggg tgaaaagcga 1980 aat 1983 <210> 1602 <211> 524 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(182..1753) <400> 1602 Met Met Lys Thr Ile Thr Lys Gln Pro Ile Leu Phe Thr Asp Val Pro 1 5 10 15 Val Ala Asp Leu Arg Asn Ser Met Lys Gln Asp Leu Asn Gln Asn Leu 20 25 30 Ile Glu Arg Leu Trp Asn Lys Ile Arg Asp Phe Phe Leu Asp Ser Asp 35 40 45 Lys Gln Lys Ala Phe Lys Ser Ile His Lys Tyr Ile Asn Thr Leu Ser 50 55 60 Val Leu Asn Tyr Asn Ser Ala Leu Thr Pro Asp Pro Asn Phe Asn Ile 65 70 75 80 Asp Ala Thr Ser Asp Leu Asp Ser Tyr Leu Lys Leu Asp Phe Asp Arg 85 90 95 Leu Ser Pro Lys Gln Lys Gln Thr Thr Leu Cys Cys Phe Trp Asn Lys 100 105 110 Ile Ala Ser Ser Leu Pro Glu Pro Tyr Asn Ser Thr Ile Lys His Asn 115 120 125 Ile Ile Phe Tyr Lys Asp Gly Glu Asn Leu Met Ile Arg Gly Thr Ile 130 135 140 Ser Ile Val Asn Glu Val Val Lys Thr Tyr Ser Leu Pro Ile Glu Lys 145 150 155 160 Asp Asp Asn Gly Tyr Tyr Asp Phe Ser Gly Leu Tyr Leu Ala His Ser 165 170 175 Asn Ile Ser Gly Lys Asp Pro Asn Lys Asp Pro Asp Ile Asp Phe Gly 180 185 190 Ile Asp Met Gly Asn Cys Asn Cys Ser Asn Val Asn Phe Glu His Thr 195 200 205 Tyr Phe Tyr Gly Val Lys Phe Thr Asn Ala Asn Cys Thr Asn Ala Asn 210 215 220 Phe Asn Asn Cys Arg Phe Lys Lys Cys Asp Leu Thr Asn Met Asn Cys 225 230 235 240 Thr Gly Ala Ile Leu Asp Asn Ala Met Ile Tyr Gly Lys Glu Lys Glu 245 250 255 Pro Glu Met Gln Tyr Pro Glu Ala Asp Gln Ile Ile Gln Arg Ile Thr 260 265 270 Tyr Gln Lys Ser Asp Gly Asn Glu Thr Lys Gly Met Ile Leu Thr Asn 275 280 285 Cys Ser Cys Val Lys Thr Thr Phe Asn Trp Ala Asp Leu Ser Glu Ser 290 295 300 Asp Cys Gln Asn Val Asp Phe Ser Glu Ala Asn Leu Ser Asn Thr Ile 305 310 315 320 Leu Pro Asp Ile Val Arg Met Lys Gly Thr Lys Leu Tyr Arg Thr Asp 325 330 335 Leu Phe Asn Pro Ile Leu Lys Thr Glu Ala Glu Ser Thr Glu Glu Lys 340 345 350 Asp Ile Ser Pro Leu Ala Lys Ile Ile Leu Asp Tyr Ile Glu Ser Asp 355 360 365 Lys Asn Pro Glu Ser Leu Asn Phe Glu Glu Lys Ser Thr Val Ile Lys 370 375 380 Ile Lys Gln Asp Ile Asp Asn Phe Ile Phe Tyr Asn Gln His Leu Lys 385 390 395 400 Lys Ile Phe Asn Arg Ala Met Asn Leu Gln Glu Lys Ile Ser Arg Lys 405 410 415 Lys Tyr Asn Glu Phe Phe Lys Tyr Ile Gln Ala Glu Ala Lys Gln Tyr 420 425 430 Phe Lys Asp Gln Tyr Lys Leu Thr Lys Asn Asp Tyr Leu Lys Lys Val 435 440 445 Pro Leu Thr Ala Gln Leu Ile Ala Lys Tyr Lys Met Asp Asp Gln Leu 450 455 460 Asp Gln Leu Leu Val Thr Arg Glu Ile Gln Asp Glu Ile Lys Ser Lys 465 470 475 480 Ile Gln Asp Lys Ile Asp Glu Leu Ser Lys Asn Leu Phe Asn Thr Met 485 490 495 Thr Glu Thr Ile Glu Asn Asn Phe Asp Asp Ile Phe Arg Gln Gln Ser 500 505 510 Glu Asn Met Ser Asn Tyr Tyr Glu Phe Val Asp * 515 520 <210> 1603 <211> 1939 <212> DNA <213> Escherichia coli O157:H7 <400> 1603 tatgaataga attaatatat tggtcatctg tatggtctta ttttttatga ctggcaatgc 60 atgtgccaca gagtggatca gtagcgagga ccttatcacc tctgactttc atcttatgac 120 ggcagatgag cgcaacgtgg ttaaagcggc aaccgacgat agtatggaag ctgcttatat 180 gctaaaagat aatatccgct ggtattatca taatggtgac ctatcattac ccgctaactt 240 cagcaataaa aataaactgg tggtgaacgg taatttaacg atttccggcg attatgatga 300 ttatctgtca ggtaatggtc atctgattgt attaggtaat gttattgtcg ataactttat 360 taatcatgat ttcgcgtatg tcaaaggaca gatgacagcg aaaggtttag tttatgctga 420 ttacaatgat cataactttg aagtgatgaa gggaattagt gcgcgaggca ttattgtttc 480 cgataaagca acgcaatttg aagtcattaa agctgaattt tatatcaatg aagatggaag 540 tggtgaagga tataactggg atgagaatat tcaaaaagcc tattcactgg tgactgccga 600 tctttatgat cacactgaaa tcgaaaccga taacatttcc aatgcgtatc ctgactatga 660 tagcgtcgca gacaacatcg ttcagggttt accgcttttt cgagataaag ccgctcctga 720 aattaatgag aaattaaaat ggattgaaac ggggaaactc gataatttcc cagcgaataa 780 aataaagcat caagatccac tggtggcacg ttttctgact catacagaga gtttatcacc 840 cgccgttatg ctgcaactgt tacagcaccc cgatgaccag acgcgtgaat cgatggcgca 900 gtcctggccc gctcaacaga tgcattggct taccgatgaa ttaattaaag atgaggctgt 960 tgccagaggg ctggttaaaa acagtaatat ttccgccgat gtgaataaaa aattaatgtc 1020 tgtacccgtc gagagcgtac agctggagca ggccagacag gataatcttt ctccagatat 1080 tgttgcgtcg ttaagtcata gcccctttct cagtgtacgc aagacattac tcagccatta 1140 cgattacgcc tggctggttc cgactgcagt ggccgatgag ttgataaata acgaagaccc 1200 ggagttacgt gaaagaatta ccggagcaga tttaaccgca caacaagcag tgatgttgag 1260 taaagataaa tcactgaaag ttcgtgaagc attagcccgg acgcttactg aattaaaaat 1320 tacccaactg tcagcaaccc tgcgtacaga ggatattgaa cgtatcgcag aacaaatgta 1380 tctggataat aaagaaaata aaaatatcgt aaaggtgtta ttgatagcgt tgccggagat 1440 gtgtcaactg tctctggcaa aagaagatgt gcacaatttg cgcgaaggtg cgcgttatct 1500 gacatcgaag gacgtgatta gttatctatt gactcagcat gatgttccca ccgtctggga 1560 tgagctggca cgcgataaat tattgccgct ggaatataag aaacagttat ggcaacgcac 1620 attaaattta atgatgagca aacggcaaga agatcaagag caagcctacg aagtacagct 1680 ggcgctgatt gataatggtg ttgttgacga agagatgtta aataatgcca ttgatttact 1740 ggttgattta cccgctgaat accgctatcg aatgcgtaac caattatttg ataataaaga 1800 attaccttcc ggaattatca acaaactcga tcaacagtat cgcttcaact ctgactgggc 1860 gctggctgtt gtcagtatga aaaatagcac ccgtagacaa agtgaaagag gattacaccg 1920 ctggaaccat gaggatagc 1939 <210> 1604 <211> 1879 <212> DNA <213> Escherichia coli O157:H7 <400> 1604 tcattcggta gccagtatgt gcaaccatca tccccatcac acaggctccc agcgccaggc 60 ctgcatccat cgcattgaag aagagggagt ttgcgacacc gattttatgc ggttccactg 120 aactgataat ctgcgtctga aaaactggcg tcacggaacc atacccgata ccaatcaacg 180 cgccagaaac gaccatcatt acgctgccct gggtgtagcc gagaaccacc agcccaaccg 240 taaagaacag caggcagggg taaaccacat atttcgggcc ttttttgtcg caaacattgc 300 cggtgaaggt acggcagatc atcaggaaga tggcgtagca gagcaggaaa ttactggccg 360 ccgacatcag attaagttcg cgggcgtaaa gcgccagaaa ggcagaaacc ccggcatacg 420 aaaaggtcat aaagaatgta accatggcaa acggcaatgc cgcgcgatcg aacatggcgg 480 cgaagcccat ctttggcttt gaaccgtcgg catggctgat aaccggcggc acggtcataa 540 tcagcgacag gataatcccc accgccgcaa cgccagtaca taaccagaaa gccatattaa 600 aggcctccca gcgcgccata ttcaggccaa tccacggccc gaccaccatt gccagcccca 660 ttgccagaga gaaaaaactg atgccctccc cacgtcggga ggccgggatc agccgcgcgg 720 aaatcgttcc ctttaccgtt gtgataaccc cgaaggtaat accatgaagc accctaataa 780 aaagcagtga ttctattgag tggcaaaaag gatacagcgc agtgaccacc aaaaaggcca 840 gagaagagag caccagaata gttttattcg aatatttacc cacccattgc ccggcaaagg 900 gtcgaataac aatcgccgca attaaaaata aagtcaccaa caaacctgct ttatcaggag 960 aggcatgcaa gcggtcagag atataaattg gcaacaatgt tagtaaaaca taaaagacga 1020 agaaaataat aaagctgatg atggttattg cccaaaaatc cttcgtccat aacttctctt 1080 tcatactcta ccgcctgtca ggatgacgca cgcagacaac actcccgtta ctgcggttgc 1140 gtcaaattgt gatgtacttt gcagaacaga agtataaatg gcggcatgct attagagaaa 1200 ttaatcgttt taatattatt gattagcaaa ctctaatgac tcttacccaa ataaattctt 1260 tactcgccgt gctggattac ggtggcttta ctgaagccag caagcgattg ttcatgacgc 1320 agtcggcggt aagtcaggca attgctgccc tcgaacaaga acttggtgtg aatatactgt 1380 tacgcgatcg ccgtaaagct atacaactga ccacagcagg tcaccgcatt gtgcaacatc 1440 tgcgcgccat taatcgggaa gttaacgcag taaaagagat agccgagcag gaaaagcaga 1500 accctcaaag aacgctgaga cttggttgtt tccccagcgt ctgcgcctgt atcttaccgg 1560 ttgtgattcg ctactttgaa attcatcatc cgaatataaa aattattcct tttgaggaaa 1620 atagcacagc gattattgat tcgcttcaga atgaatccat tgatgccggt tttgttcatt 1680 ttccggtgag cggaatgtac tccgtgccca tttatcagga taaattcacc gtagtgttac 1740 cgcccaacca tgctctggca aaaaacagca ctattacagt ggaagaatta atgggtgaac 1800 cattaatcat tagtaaagga cgctatgaat taagcattat ggcactattt aaagaaaaga 1860 atattacccc acagataaa 1879 <210> 1605 <211> 1834 <212> DNA <213> Escherichia coli O157:H7 <400> 1605 gcggggctga cgccgaagtg agatttaaaa tgctgacgcc aggtcacagg tgagagaaaa 60 cccacctcag ccgctatccg ctcaacgggc aactgactgg atcccaacag ttcctggcta 120 cggcgtaagc gttcagtaat gagccattcg gcgatactcg aaccggtcgc tttcataaaa 180 tggcgagtta atgtgcggcg actcatcatt actcgctgcg ccagcgagtc gagatcatgc 240 tgttgcgcaa tgttttgccg caggtaatcc agcaggaggt ttatgcgttc atcatgggta 300 tttttcggca ccggttgctc aataaactgc gcctgaccgc cggtgcgata tggcggtacg 360 accatccgtc gggcaatatg gttagcatag tcgctgccaa aatgttgccg aacaatatac 420 aaacagcaat ccagcgccgc ggcagtaccg gcagaggtaa taatgccgtc atcgtctacg 480 tacaacgcgt taatatccag atgtgtttgt ggaaaacgtg cctgaaattc acgctcgaac 540 tcccagtgcg tggcggcacg cttatttttc agtaaacctg catagccgag cacaaacgtg 600 cccaggcaaa gcccgacaat ctgtgcgccg ttatcccgtg cggtcgttaa ggcttccagc 660 agtttttgtg gcggtttttg tgtaatggtt ccccagtaag gaattatcac aatatctgcc 720 tggatgactg cggtatagtc atgggtggcg gttacggaaa acccatcggc agagtccacg 780 tttcccggct tttcagcgca aataatcacg tgaaagcgtt ttttctccgc catcttttca 840 ctaaacacga taaacggtac ggaaaggtga aaaggactaa aaccggcaac ggcgataatg 900 gcaacagtta gcgggcgcat aacactcttt atctccgaat tagaatgtca acgtttcacc 960 atcttctggt acgttcacaa attcgataat ttgattatct ctggcgtatt ccttgagcgc 1020 atcacgcgtc agcaaacagt ggtttacggc ctccatatgt gtcgcgataa tttgcgcttc 1080 tgggagggta aaatgtgttt tgagaatatc ttctgctccc ataattatcg cgccatgccc 1140 cagaacatgc gcaaatccgg cattcaacac aaccacttct ggttggaaag ttagcattgt 1200 agcctcgacg tcgtcacgcc agagggtatc gccagccaga tagagcgttt tctctgtcgg 1260 gtgctggaaa acaacgccgc aagctgcgcc taaacgcttc gccatcgccg ggtcggcata 1320 ggtgcgatcg gagccgtgct gccctgtcgt tttatgcaga gtaatatcgc caaatttagt 1380 ctcgtcggta agtacggtaa gatgcgtaaa tccttgttta ttcagtgatt cagcatcttg 1440 ctcattttgc acataaatca gtttatcttt agggacgacg cgggaggctg tttcgtccca 1500 gtgatcttca tgcaaatggg tcacgattag ggcgtcaacg ttgagtaacg ttgttaaatc 1560 gcacggtaat tctaccgttg gattgcggat ttctgcgcgt gccgttccgg caaaacccgg 1620 ataacttcct ttaggcgcga gtaacgggtc gataagaaat gttttgccag cgtattggat 1680 aatttgggtg gcattacgaa tttgcgtaat tttcatgatt tgctccacat cacagtattg 1740 atgtcattag cgtagcgtgc agcccgtact gtgcatgtgg gcaaatgggc gaataacgat 1800 gagaatgggc caaattacac attggcgtaa ctag 1834 <210> 1606 <211> 263 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(940..1728) <400> 1606 Val Glu Gln Ile Met Lys Ile Thr Gln Ile Arg Asn Ala Thr Gln Ile 1 5 10 15 Ile Gln Tyr Ala Gly Lys Thr Phe Leu Ile Asp Pro Leu Leu Ala Pro 20 25 30 Lys Gly Ser Tyr Pro Gly Phe Ala Gly Thr Ala Arg Ala Glu Ile Arg 35 40 45 Asn Pro Thr Val Glu Leu Pro Cys Asp Leu Thr Thr Leu Leu Asn Val 50 55 60 Asp Ala Leu Ile Val Thr His Leu His Glu Asp His Trp Asp Glu Thr 65 70 75 80 Ala Ser Arg Val Val Pro Lys Asp Lys Leu Ile Tyr Val Gln Asn Glu 85 90 95 Gln Asp Ala Glu Ser Leu Asn Lys Gln Gly Phe Thr His Leu Thr Val 100 105 110 Leu Thr Asp Glu Thr Lys Phe Gly Asp Ile Thr Leu His Lys Thr Thr 115 120 125 Gly Gln His Gly Ser Asp Arg Thr Tyr Ala Asp Pro Ala Met Ala Lys 130 135 140 Arg Leu Gly Ala Ala Cys Gly Val Val Phe Gln His Pro Thr Glu Lys 145 150 155 160 Thr Leu Tyr Leu Ala Gly Asp Thr Leu Trp Arg Asp Asp Val Glu Ala 165 170 175 Thr Met Leu Thr Phe Gln Pro Glu Val Val Val Leu Asn Ala Gly Phe 180 185 190 Ala His Val Leu Gly His Gly Ala Ile Ile Met Gly Ala Glu Asp Ile 195 200 205 Leu Lys Thr His Phe Thr Leu Pro Glu Ala Gln Ile Ile Ala Thr His 210 215 220 Met Glu Ala Val Asn His Cys Leu Leu Thr Arg Asp Ala Leu Lys Glu 225 230 235 240 Tyr Ala Arg Asp Asn Gln Ile Ile Glu Phe Val Asn Val Pro Glu Asp 245 250 255 Gly Glu Thr Leu Thr Phe * 260 <210> 1607 <211> 1819 <212> DNA <213> Escherichia coli O157:H7 <400> 1607 tatgaattct gaaatatagc aagggcggta ctattttaca taagtttcat tcatacttcg 60 ccttgggcga acaggacgta ttgcaatgag tagacatgat attttactga ggtcgcaatt 120 tgaacggata atagagggtg atcgcgttgg tcaggcttta atatctttct atgaaaaact 180 tccagaggaa aattaccgac gcgcgctgta tattttatca ataatttatc cgattaaact 240 taacgtcggt gacgacgaat ttaagtttat tttttacatc atgtcacaga aaaaatttct 300 acgccaacag accattagcg attttgtacg ctcaataaat gttattgaat ttactgaaac 360 tcaaaaaagt gttttgcgtg aacttattaa aaagaataat gatatcataa ttacgcaatg 420 cacatttgag ctagattgtt tgttaacgag agtatctgcg tcatcgaacc agtttagaaa 480 ctctaatggt tacttacctg agaatagtta atagcatgaa aaatgtagaa aatattatct 540 ggcatgatgg tgttttagta gaaaccagaa tggaatgtca ccacaccgag tataatttta 600 tattgacggc ggagctttat gttgatgaat ttacagccgg aagggaacga aaaaggttcg 660 agtttacagg agtggaacat ttatcgcagg ttatggatat tgctgaactt atagataacc 720 aaaatgcagg taatattaaa gatgcgacaa ttgtttataa ggcaaagaag tataaaattt 780 cacttcattt gtttggtggt tttttaagtt ttacatttaa aaccatgcga gttattgaca 840 atgaatgtgc gtaatgtcaa attcgacaac ttgtcttttt atgaagaaaa aatccgctgg 900 cgaatgcgtc ggcaaatctc gaatgcagag gcaatatttt acgagaatca ggaagaacac 960 attcggcgct ttttaggcag atatacctgt cgcaaaccgg ttcttgttta ttgggaaagt 1020 gaacaaagat ggacatctgt aaacggtctg gaagtgatga gtatgtttgg tgaacattgt 1080 catcacatct accttgatga tatcaagaaa aaaatacaaa ctgaattacc tgaaaataaa 1140 actttagatt tcaaacgtca attgcaattt ataatattag gggatgataa gattagaata 1200 tgggtgcctg aggggaaatt gtatttcgca ttaatgaatg tattgcagat gtttcccatg 1260 aaaaatggtt aataactgga caagataatt ttaaaattca gcaacggtta tcgattatac 1320 atggtactta aacagactca caccattttt gtagaaggtt aaattgagta cagtctcata 1380 tattaagggt gttaacatgg atgaacgttt tataaatatc acgccgactt cgttgtcttt 1440 taaacacgcc gatctgtcag gtttaagcta taagaatgcc aggcttgaac tggccctgat 1500 atgcccggcg atcaagtcag aagttaagat atcatttgac tggatacact catttcgtgt 1560 tactgacgaa ggtgatttgt taggtatgtc aggaaagcag ggaattaacc aaacggggat 1620 ctatagagta gccaattcca cttatcttac atggtttact atgcaaagtt gtgaaattca 1680 taaaaataaa atgatcgaac attatgttat tgccacgtca aatgatgtta ttgatgtttt 1740 atcaacagtt tctccgcaaa tagtgtatga ctaaaaccag tgtctggttc gcgatggcga 1800 gatagaaaaa gcattatct 1819 <210> 1608 <211> 142 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(86..511) <400> 1608 Met Ser Arg His Asp Ile Leu Leu Arg Ser Gln Phe Glu Arg Ile Ile 1 5 10 15 Glu Gly Asp Arg Val Gly Gln Ala Leu Ile Ser Phe Tyr Glu Lys Leu 20 25 30 Pro Glu Glu Asn Tyr Arg Arg Ala Leu Tyr Ile Leu Ser Ile Ile Tyr 35 40 45 Pro Ile Lys Leu Asn Val Gly Asp Asp Glu Phe Lys Phe Ile Phe Tyr 50 55 60 Ile Met Ser Gln Lys Lys Phe Leu Arg Gln Gln Thr Ile Ser Asp Phe 65 70 75 80 Val Arg Ser Ile Asn Val Ile Glu Phe Thr Glu Thr Gln Lys Ser Val 85 90 95 Leu Arg Glu Leu Ile Lys Lys Asn Asn Asp Ile Ile Ile Thr Gln Cys 100 105 110 Thr Phe Glu Leu Asp Cys Leu Leu Thr Arg Val Ser Ala Ser Ser Asn 115 120 125 Gln Phe Arg Asn Ser Asn Gly Tyr Leu Pro Glu Asn Ser * 130 135 140 <210> 1609 <211> 113 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(516..854) <400> 1609 Met Lys Asn Val Glu Asn Ile Ile Trp His Asp Gly Val Leu Val Glu 1 5 10 15 Thr Arg Met Glu Cys His His Thr Glu Tyr Asn Phe Ile Leu Thr Ala 20 25 30 Glu Leu Tyr Val Asp Glu Phe Thr Ala Gly Arg Glu Arg Lys Arg Phe 35 40 45 Glu Phe Thr Gly Val Glu His Leu Ser Gln Val Met Asp Ile Ala Glu 50 55 60 Leu Ile Asp Asn Gln Asn Ala Gly Asn Ile Lys Asp Ala Thr Ile Val 65 70 75 80 Tyr Lys Ala Lys Lys Tyr Lys Ile Ser Leu His Leu Phe Gly Gly Phe 85 90 95 Leu Ser Phe Thr Phe Lys Thr Met Arg Val Ile Asp Asn Glu Cys Ala 100 105 110 * <210> 1610 <211> 144 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(841..1272) <400> 1610 Met Asn Val Arg Asn Val Lys Phe Asp Asn Leu Ser Phe Tyr Glu Glu 1 5 10 15 Lys Ile Arg Trp Arg Met Arg Arg Gln Ile Ser Asn Ala Glu Ala Ile 20 25 30 Phe Tyr Glu Asn Gln Glu Glu His Ile Arg Arg Phe Leu Gly Arg Tyr 35 40 45 Thr Cys Arg Lys Pro Val Leu Val Tyr Trp Glu Ser Glu Gln Arg Trp 50 55 60 Thr Ser Val Asn Gly Leu Glu Val Met Ser Met Phe Gly Glu His Cys 65 70 75 80 His His Ile Tyr Leu Asp Asp Ile Lys Lys Lys Ile Gln Thr Glu Leu 85 90 95 Pro Glu Asn Lys Thr Leu Asp Phe Lys Arg Gln Leu Gln Phe Ile Ile 100 105 110 Leu Gly Asp Asp Lys Ile Arg Ile Trp Val Pro Glu Gly Lys Leu Tyr 115 120 125 Phe Ala Leu Met Asn Val Leu Gln Met Phe Pro Met Lys Asn Gly * 130 135 140 <210> 1611 <211> 126 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1397..1774) <400> 1611 Met Asp Glu Arg Phe Ile Asn Ile Thr Pro Thr Ser Leu Ser Phe Lys 1 5 10 15 His Ala Asp Leu Ser Gly Leu Ser Tyr Lys Asn Ala Arg Leu Glu Leu 20 25 30 Ala Leu Ile Cys Pro Ala Ile Lys Ser Glu Val Lys Ile Ser Phe Asp 35 40 45 Trp Ile His Ser Phe Arg Val Thr Asp Glu Gly Asp Leu Leu Gly Met 50 55 60 Ser Gly Lys Gln Gly Ile Asn Gln Thr Gly Ile Tyr Arg Val Ala Asn 65 70 75 80 Ser Thr Tyr Leu Thr Trp Phe Thr Met Gln Ser Cys Glu Ile His Lys 85 90 95 Asn Lys Met Ile Glu His Tyr Val Ile Ala Thr Ser Asn Asp Val Ile 100 105 110 Asp Val Leu Ser Thr Val Ser Pro Gln Ile Val Tyr Asp * 115 120 125 <210> 1612 <211> 1817 <212> DNA <213> Escherichia coli O157:H7 <400> 1612 agaatattct caaattgcct gttaccaatg tgaataatta gttttgttca tctaatttga 60 gtttttcctt atattaccac catcattttg aaacaatttg taacatcaag agacctttga 120 atcattactc gttaatattt cttattaaag agaacatatt ttcgcaagca atagttatta 180 ctgtttgttt atggatagag agtctactta atgggtacag cagctataag tcatttacga 240 tatgatctta acaaatatgc cctttcttta cgcaaaaccg caacacttgc ttcaacattt 300 tttattgagt ccccattagt tagattcgag tatctgcaag aaatagaaaa tactattaat 360 gatattactc acagattcaa ttcttcatat gacatcaatg aaaaagcacg acttatcaat 420 gaattaaaaa tggagtcaga aacagcaaga aaagaatatc aacttttcag acaaggaaat 480 tatgataaat atatcactac tgatattttc gaagaacatg gtttgataaa atatgtgaac 540 ttaagtttcg atattgttgc atctgtagga caggtcgtag gcggggttgg cgcgttgaaa 600 tttggtaagg tagtgcattc aaaccgaata aaaggtatag gcgtcacatt agttgctcat 660 ggggcgaata atttttatga aagcttatca cctttatttt ttaacgagta tgattcaggt 720 ccaatacgtg aactctacag agtaatagca aaaaaaatgg gaggtgatat taattctgct 780 gattatgcat acagcatcgt ggacttttcg attactgcat atggtggata ttcaggcatg 840 aaaatcgtac ctaagtataa tagattgatt cgtccttcat taggaaatag acctggtaca 900 ggacgattat ttcattacac atcagttgat tttaaaaata aattctcatt aaaacctacc 960 cctttaaaaa tcatacaaat tagttctact gtaaaaaaat tcaaggttac attttatgat 1020 gaaaatacaa atttgaggat aaaacatggc ctcaataatc atatgccaca tcaattatta 1080 atgaatatat caggaactac aactggtgca ggaatacaat aacagaataa cttaatttta 1140 agataaaaca ttttgaggca taattggtaa gagaatttag tatccagttt tctgtgtatg 1200 ataagaatag cgaacatggc aatactaacg attgaagaca gaaaaaaact tttcaacata 1260 ttatcctgaa aaaatgagaa tacaagcaat atcccattaa ctatacttac caacccaaac 1320 cccaaagagc aataacccac cattgaaata atagcatcaa tgaaattttg ttctacgaga 1380 gagacttcat gcttattagc aagtttcttc atttctttgt atcttgattt taaatagaag 1440 agttcttgtt tattaagtac agagagaatc acgtattttg ctttcattat tcccccttaa 1500 aaacacttta caaaatcgat caaagtcatg atgaatgcca ttatgcacat aaacaacaca 1560 aagcgtgata tttaaatcaa taaattacac tctaaaatga actataacta cagtttattt 1620 aatagcatag ttaattcctt tcctgaatat caggaagtaa ttatcgcacg tcctattttc 1680 acggtaaatg aaagactatt ctgcatactc ttgaaaagaa agcataacct aagcccctta 1740 aaagcattca ggataattat gattatatat tacggagcaa tagtaaaagc aatccagaca 1800 ctaatttatc ttgttca 1817 <210> 1613 <211> 304 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(211..1122) <400> 1613 Met Gly Thr Ala Ala Ile Ser His Leu Arg Tyr Asp Leu Asn Lys Tyr 1 5 10 15 Ala Leu Ser Leu Arg Lys Thr Ala Thr Leu Ala Ser Thr Phe Phe Ile 20 25 30 Glu Ser Pro Leu Val Arg Phe Glu Tyr Leu Gln Glu Ile Glu Asn Thr 35 40 45 Ile Asn Asp Ile Thr His Arg Phe Asn Ser Ser Tyr Asp Ile Asn Glu 50 55 60 Lys Ala Arg Leu Ile Asn Glu Leu Lys Met Glu Ser Glu Thr Ala Arg 65 70 75 80 Lys Glu Tyr Gln Leu Phe Arg Gln Gly Asn Tyr Asp Lys Tyr Ile Thr 85 90 95 Thr Asp Ile Phe Glu Glu His Gly Leu Ile Lys Tyr Val Asn Leu Ser 100 105 110 Phe Asp Ile Val Ala Ser Val Gly Gln Val Val Gly Gly Val Gly Ala 115 120 125 Leu Lys Phe Gly Lys Val Val His Ser Asn Arg Ile Lys Gly Ile Gly 130 135 140 Val Thr Leu Val Ala His Gly Ala Asn Asn Phe Tyr Glu Ser Leu Ser 145 150 155 160 Pro Leu Phe Phe Asn Glu Tyr Asp Ser Gly Pro Ile Arg Glu Leu Tyr 165 170 175 Arg Val Ile Ala Lys Lys Met Gly Gly Asp Ile Asn Ser Ala Asp Tyr 180 185 190 Ala Tyr Ser Ile Val Asp Phe Ser Ile Thr Ala Tyr Gly Gly Tyr Ser 195 200 205 Gly Met Lys Ile Val Pro Lys Tyr Asn Arg Leu Ile Arg Pro Ser Leu 210 215 220 Gly Asn Arg Pro Gly Thr Gly Arg Leu Phe His Tyr Thr Ser Val Asp 225 230 235 240 Phe Lys Asn Lys Phe Ser Leu Lys Pro Thr Pro Leu Lys Ile Ile Gln 245 250 255 Ile Ser Ser Thr Val Lys Lys Phe Lys Val Thr Phe Tyr Asp Glu Asn 260 265 270 Thr Asn Leu Arg Ile Lys His Gly Leu Asn Asn His Met Pro His Gln 275 280 285 Leu Leu Met Asn Ile Ser Gly Thr Thr Thr Gly Ala Gly Ile Gln * 290 295 300 <210> 1614 <211> 139 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(1071..1487) <400> 1614 Met Lys Ala Lys Tyr Val Ile Leu Ser Val Leu Asn Lys Gln Glu Leu 1 5 10 15 Phe Tyr Leu Lys Ser Arg Tyr Lys Glu Met Lys Lys Leu Ala Asn Lys 20 25 30 His Glu Val Ser Leu Val Glu Gln Asn Phe Ile Asp Ala Ile Ile Ser 35 40 45 Met Val Gly Tyr Cys Ser Leu Gly Phe Gly Leu Val Ser Ile Val Asn 50 55 60 Gly Ile Leu Leu Val Phe Ser Phe Phe Gln Asp Asn Met Leu Lys Ser 65 70 75 80 Phe Phe Leu Ser Ser Ile Val Ser Ile Ala Met Phe Ala Ile Leu Ile 85 90 95 Ile His Arg Lys Leu Asp Thr Lys Phe Ser Tyr Gln Leu Cys Leu Lys 100 105 110 Met Phe Tyr Leu Lys Ile Lys Leu Phe Cys Tyr Cys Ile Pro Ala Pro 115 120 125 Val Val Val Pro Asp Ile Phe Ile Asn Asn * 130 135 <210> 1615 <211> 1761 <212> DNA <213> Escherichia coli O157:H7 <400> 1615 tcttgtgaat aaagagttat tatttaatga ttttgtgaat gtttaaatgt ctcagataat 60 ttgtctaaac gttatttata tttgtggctt atgagccagc ttgaatcata tctaatattt 120 tttacgatat ttagttaaaa acggcactat tgttatattc ctcacgttcc aggaaatcag 180 cggatttact catattatgc ggcgggatac tatccatcgg cctgctgaag ttggattaaa 240 aattcgaaag tgcacacctt atatttctct atatacgtat tccttttgga aagcgtaggg 300 tctcctttat ttcagggaac gtaaataatg aaaaaatcga cattatcttt agccatcggt 360 ttattattgg catgtagtac cggtatggca aaaacacagc atttaatgct ggaacaacgc 420 atggcattgc tggaagaacg cctggaagcg gcagaaatgc gggcggcaaa agcagagagc 480 caggttaaac agctgcagac acaacaagcc gctgagatcc gcgaaattaa ggccgctcag 540 ggcaatacgc cggtaaatgg acaggcaacg gcggaatctg caaagaaaaa tgccacctca 600 cctaatcttt tgctttcagg ttatggcgat ttaaaaatct acggcgacgt agaatttaat 660 atggatgcgg aaagtaatca tggcctgctg gcaatgacca acgctgatgt gaatagcgat 720 cccactaatg aacagtggaa tctcaatggt cgtattctgt taggttttga cggtatgcga 780 aagatggaca acggttattt cgccgggttc tccgcacaac cgctgggtga tatgcacggt 840 tcagtaaata tcgatgatgc ggtattcttc tttggcaaag aaaacgactg gaaggtcaaa 900 gtaggccgtt ttgaagccta cgatatgttc ccattgaatc aggatacctt tgttgaacat 960 tccggtaata ctgcgaacga tctttatgac gatggcagcg gttatatcta tatgatgaaa 1020 gagggccgcg ggcgctctaa cgctggcggt aatttcctcg tcagcaaaca actcgataac 1080 tggtattttg aattaaacac gttacttgaa gacggaacat ctttatataa tgacggtaat 1140 tatcatggac gcgatatgga gcagcagaaa aatgttgctt atctgcgccc agtaattgcc 1200 tggtcgccga cggaagaatt caccgtttcc gcagcgatgg aagcgaacgt ggtaaataat 1260 gcttatggtt ataccgatag caagggtaat tttgtcgatc agtccgatcg taccggctat 1320 ggtatgagca tgacctggaa cggcctgaaa acggatccgg acaatggcat tgtggttaat 1380 ctaaataccg cctatttaga tgctaataat gagaaagatt tcactgccgg gattaacgcg 1440 ctgtggaaac gtttcgagct cggttatatc tacgcgcaca ataagattga tgaattcagc 1500 ggtgtagttt gtgataacga ctgctgcatt gatgatgaag ggacgtacac cattcacacc 1560 attcatgcgt cttatcagtt cgctaacgtg atggatatgg agaactttaa tatttacctc 1620 gggacgtatt actccattct ggatagcgac ggcgataaaa aacacggtga tgatactgat 1680 gaccgttacg gcgcacgcgt tcgctttaaa tacttcttct gatgaagtcg cggtgctgga 1740 tattttccgg caccgcaact c 1761 <210> 1616 <211> 465 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(328..1722) <400> 1616 Met Lys Lys Ser Thr Leu Ser Leu Ala Ile Gly Leu Leu Leu Ala Cys 1 5 10 15 Ser Thr Gly Met Ala Lys Thr Gln His Leu Met Leu Glu Gln Arg Met 20 25 30 Ala Leu Leu Glu Glu Arg Leu Glu Ala Ala Glu Met Arg Ala Ala Lys 35 40 45 Ala Glu Ser Gln Val Lys Gln Leu Gln Thr Gln Gln Ala Ala Glu Ile 50 55 60 Arg Glu Ile Lys Ala Ala Gln Gly Asn Thr Pro Val Asn Gly Gln Ala 65 70 75 80 Thr Ala Glu Ser Ala Lys Lys Asn Ala Thr Ser Pro Asn Leu Leu Leu 85 90 95 Ser Gly Tyr Gly Asp Leu Lys Ile Tyr Gly Asp Val Glu Phe Asn Met 100 105 110 Asp Ala Glu Ser Asn His Gly Leu Leu Ala Met Thr Asn Ala Asp Val 115 120 125 Asn Ser Asp Pro Thr Asn Glu Gln Trp Asn Leu Asn Gly Arg Ile Leu 130 135 140 Leu Gly Phe Asp Gly Met Arg Lys Met Asp Asn Gly Tyr Phe Ala Gly 145 150 155 160 Phe Ser Ala Gln Pro Leu Gly Asp Met His Gly Ser Val Asn Ile Asp 165 170 175 Asp Ala Val Phe Phe Phe Gly Lys Glu Asn Asp Trp Lys Val Lys Val 180 185 190 Gly Arg Phe Glu Ala Tyr Asp Met Phe Pro Leu Asn Gln Asp Thr Phe 195 200 205 Val Glu His Ser Gly Asn Thr Ala Asn Asp Leu Tyr Asp Asp Gly Ser 210 215 220 Gly Tyr Ile Tyr Met Met Lys Glu Gly Arg Gly Arg Ser Asn Ala Gly 225 230 235 240 Gly Asn Phe Leu Val Ser Lys Gln Leu Asp Asn Trp Tyr Phe Glu Leu 245 250 255 Asn Thr Leu Leu Glu Asp Gly Thr Ser Leu Tyr Asn Asp Gly Asn Tyr 260 265 270 His Gly Arg Asp Met Glu Gln Gln Lys Asn Val Ala Tyr Leu Arg Pro 275 280 285 Val Ile Ala Trp Ser Pro Thr Glu Glu Phe Thr Val Ser Ala Ala Met 290 295 300 Glu Ala Asn Val Val Asn Asn Ala Tyr Gly Tyr Thr Asp Ser Lys Gly 305 310 315 320 Asn Phe Val Asp Gln Ser Asp Arg Thr Gly Tyr Gly Met Ser Met Thr 325 330 335 Trp Asn Gly Leu Lys Thr Asp Pro Asp Asn Gly Ile Val Val Asn Leu 340 345 350 Asn Thr Ala Tyr Leu Asp Ala Asn Asn Glu Lys Asp Phe Thr Ala Gly 355 360 365 Ile Asn Ala Leu Trp Lys Arg Phe Glu Leu Gly Tyr Ile Tyr Ala His 370 375 380 Asn Lys Ile Asp Glu Phe Ser Gly Val Val Cys Asp Asn Asp Cys Cys 385 390 395 400 Ile Asp Asp Glu Gly Thr Tyr Thr Ile His Thr Ile His Ala Ser Tyr 405 410 415 Gln Phe Ala Asn Val Met Asp Met Glu Asn Phe Asn Ile Tyr Leu Gly 420 425 430 Thr Tyr Tyr Ser Ile Leu Asp Ser Asp Gly Asp Lys Lys His Gly Asp 435 440 445 Asp Thr Asp Asp Arg Tyr Gly Ala Arg Val Arg Phe Lys Tyr Phe Phe 450 455 460 * <210> 1617 <211> 1748 <212> DNA <213> Escherichia coli O157:H7 <400> 1617 ttgacatcct ccacgccctg aatgacgagg atccctgcta cgttcaggct gtcgcctgaa 60 tcatttcggt gggttcctgc ttcaacgagc ggcctgactg caccatctct ccacaggcaa 120 gaacggcgtg ccccgccgct aaaatgttac gagcgccgtt tacatcggcg ttcgctgtat 180 atccacatac ctggcatctg aatttacttt gtgacaggcg gttttctttc gctgtatgac 240 cacagcacgc gcaacgctgg cttgtgtacg ctggcggaac agccagtacc tgaccgccac 300 gccagagctg cttgtactca agctggcggc gcatttcata ccagccctga tccagtatcg 360 aacggtttaa acctgatttt gcccggacat tgcgccccgg ctggctgacc gtacccgctg 420 ctgactttga catgttgctg accttcaaat cctcaatgac tatcattgcg tggtttttgc 480 tgacggtcgt tgtgactttg tgaaggtagt ccctgcggat atttgcggta caggaatgca 540 gtcgctgtat tttgcgtttc tgcttctgcc agttattgct gaatttgacc ttgcggctta 600 actgtcgctg aagtctcgcc aacttcttct ggtttttctg aaaactgttt acaggctcaa 660 agactgtgcc atctgacagc gtggcgagtt tagccacgcc agcatccagt ccgaccattg 720 atgctgaagg gtgaaccgga gttgatactt cactttctgt ctgaatactg atgtaccact 780 taccgcagga ctggctgaca gtgacatttt tcacaacacc cgtgacctga cggctgttca 840 ggtagcgcat ccagccaagt ttcggcagaa aaatacggct gttttcctga tcgagcttaa 900 cgccctgcgg gtagcggaat gcatcattct gtccccgctt tttgaatcgg ggaaaagcag 960 cccgcttccg gaagaagttt ttgtaagccc gctcaagctc tttcagtgac tgttgcaatg 1020 gctgtgacgg ggcatcttta agccattgcg tttcagtggc gtttttccac tcaaccagcc 1080 aggaagccat tttcccgtaa gggatgtatt tattaccggc ctcatgattc tcattctgaa 1140 gcgccagagc acgattgaaa acgaaacgac atgcgcctgc gaagcgcctc atttcacgct 1200 cctgttgacc acctggtctt aactggaatt taaatgcctg tagtcgtttc acaggccaaa 1260 tgatactttg gtctatgaat aaagaaaccg atatccgacg gggaaggcat tgtgttttcc 1320 tgatgcatgt tcatctgttc tttgtcacca gataccgacg tcagattttt gactatgacg 1380 cgacagaaaa actacgcact tacttttcaa atgtatgtgc tgattttgaa gctgaactgg 1440 ttgaaatgga tggcgaacca gatcacgtcc atttgttaac taactatcct cccaaactgg 1500 cgatatccag tctggtaaac agcctcaaag gcgtatcggg taggttactg cgacgagatc 1560 gaccagatat tgcagtcagg tattactaca aaggcgtttt gtggagtcct ggctattttg 1620 ccagtagctg cggaggtgcg ccaatatccg tcatccgcca atacattgaa caacagcaaa 1680 cacctggtca ggtggaaaac cgcgccttat atccccgccc tgaaggacgg ggttttacgg 1740 cgcaccgg 1748 <210> 1618 <211> 383 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44..1192) <400> 1618 Met Arg Arg Phe Ala Gly Ala Cys Arg Phe Val Phe Asn Arg Ala Leu 1 5 10 15 Ala Leu Gln Asn Glu Asn His Glu Ala Gly Asn Lys Tyr Ile Pro Tyr 20 25 30 Gly Lys Met Ala Ser Trp Leu Val Glu Trp Lys Asn Ala Thr Glu Thr 35 40 45 Gln Trp Leu Lys Asp Ala Pro Ser Gln Pro Leu Gln Gln Ser Leu Lys 50 55 60 Glu Leu Glu Arg Ala Tyr Lys Asn Phe Phe Arg Lys Arg Ala Ala Phe 65 70 75 80 Pro Arg Phe Lys Lys Arg Gly Gln Asn Asp Ala Phe Arg Tyr Pro Gln 85 90 95 Gly Val Lys Leu Asp Gln Glu Asn Ser Arg Ile Phe Leu Pro Lys Leu 100 105 110 Gly Trp Met Arg Tyr Leu Asn Ser Arg Gln Val Thr Gly Val Val Lys 115 120 125 Asn Val Thr Val Ser Gln Ser Cys Gly Lys Trp Tyr Ile Ser Ile Gln 130 135 140 Thr Glu Ser Glu Val Ser Thr Pro Val His Pro Ser Ala Ser Met Val 145 150 155 160 Gly Leu Asp Ala Gly Val Ala Lys Leu Ala Thr Leu Ser Asp Gly Thr 165 170 175 Val Phe Glu Pro Val Asn Ser Phe Gln Lys Asn Gln Lys Lys Leu Ala 180 185 190 Arg Leu Gln Arg Gln Leu Ser Arg Lys Val Lys Phe Ser Asn Asn Trp 195 200 205 Gln Lys Gln Lys Arg Lys Ile Gln Arg Leu His Ser Cys Thr Ala Asn 210 215 220 Ile Arg Arg Asp Tyr Leu His Lys Val Thr Thr Thr Val Ser Lys Asn 225 230 235 240 His Ala Met Ile Val Ile Glu Asp Leu Lys Val Ser Asn Met Ser Lys 245 250 255 Ser Ala Ala Gly Thr Val Ser Gln Pro Gly Arg Asn Val Arg Ala Lys 260 265 270 Ser Gly Leu Asn Arg Ser Ile Leu Asp Gln Gly Trp Tyr Glu Met Arg 275 280 285 Arg Gln Leu Glu Tyr Lys Gln Leu Trp Arg Gly Gly Gln Val Leu Ala 290 295 300 Val Pro Pro Ala Tyr Thr Ser Gln Arg Cys Ala Cys Cys Gly His Thr 305 310 315 320 Ala Lys Glu Asn Arg Leu Ser Gln Ser Lys Phe Arg Cys Gln Val Cys 325 330 335 Gly Tyr Thr Ala Asn Ala Asp Val Asn Gly Ala Arg Asn Ile Leu Ala 340 345 350 Ala Gly His Ala Val Leu Ala Cys Gly Glu Met Val Gln Ser Gly Arg 355 360 365 Ser Leu Lys Gln Glu Pro Thr Glu Met Ile Gln Ala Thr Ala * 370 375 380 <210> 1619 <211> 1748 <212> DNA <213> Escherichia coli O157:H7 <400> 1619 cggtgcgccg taaaaccccg tccttcaggg cggggatata cggcgcggtt ttccacctaa 60 ccaggtgttt gctgttgttc aatgtattga cggatggcgg atattggcgc acctccgcag 120 ctactggcaa aatagccagg actccacaaa acgcctttgt agtaatacct gactgcaata 180 tctggtcgat ctcgtcgcag taacctaccc gatacgcctt tgaggctgtt taccagactg 240 gatatcgcca gtttgggagg atagttaatt aacaaatgga cgtgatctgg ttcgccatcc 300 atttcaacca gttcagcttc aaaatcagca catacctttg aaaagtaagt gcgtagtttt 360 tctgtcgcgt catggtcaaa aatctggcgt cggtatctgg tgacaaagac caggtgaaca 420 tgcatcagga aaacacaatg ccttccacgc cggatatcgg tttctttttt cacagaccaa 480 agtatcattt ggcctgtgaa acgactacag gcatttaaat tccagttaag acccggtggt 540 caacaggagc gtgaaatgag gcgcttcgca ggcgcatgtc gtttcgtttt caatcgtgct 600 ctggcgcttc agaatgagaa tcatgaggcc ggtaataaat acatccctta cgggaaaatg 660 gcttcctggc tggttgagtg gaaaaatgcc actgaaacgc aatggcttaa agatgccccg 720 tcacagccat tgcaacagtc actgaaagac cttgagcggg cttacaaaaa cttcttccgg 780 aagcgggctg cttttccccg attcaaaaag cggggacaga atgatgcatt ccgctacccg 840 cagggcgtta agctcgatca ggaaaacagc cgtatttttc tgccgaaact tggctggatg 900 cgctaccgga atagccgtca ggtcacgggt gttgtgaaaa atgtcactgc cagccagtcc 960 tgcggtaagt ggtacatcag tattcagact gaaaatgaag tatcaactcc ggttcaccct 1020 tcagcattaa tggtcggact ggatgctggc gtggctaaac tcgccacgct gtcagatggc 1080 acagtctttg gacctgtaaa cagttttcag aaaaaccaga agacgctggc gagacttcag 1140 cgacagttaa gccgcaaggt caaattcagc aacaactggc agaagcagaa acgcaaaata 1200 cagcgactgc attcctgtat cgcaaatatc tgcagggact accttcacaa agtcacaacg 1260 accgtcagca aaaaccacgc aatgatagtc attgaggatt tgaaggtcag caacatgtca 1320 aagtcagcag cgggtacggt cagccagccg gggcgcaatg tccgggcaaa atcaggttta 1380 aaccgttcga tactggatca gggctggtat gaaatgcgcc gccagcttga gtacaagcag 1440 ctctggcgtg gcggtcaggt gcttgctgtt ccgccagcgt acacaagcca gcgttgcgcg 1500 tgctgtggtc atacagcgaa agaaaatcgc ctgtcacaaa gtaaattcag atgccaggca 1560 tgtggatata cagcgaacgc tgatgtaaat ggcgctcgta acattttagc ggcggggcac 1620 gccgttcttg cctgtgggga gatggtgcag tcaggccgcc cgttgaagca ggaacccacc 1680 gaaatgattc aggcgacagc ctgaacgtag cagggatcca cgtccttcag ggcttggagg 1740 atgtcaac 1748 <210> 1620 <211> 144 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(57..488) <400> 1620 Met Ile Leu Trp Ser Val Lys Lys Glu Thr Asp Ile Arg Arg Gly Arg 1 5 10 15 His Cys Val Phe Leu Met His Val His Leu Val Phe Val Thr Arg Tyr 20 25 30 Arg Arg Gln Ile Phe Asp His Asp Ala Thr Glu Lys Leu Arg Thr Tyr 35 40 45 Phe Ser Lys Val Cys Ala Asp Phe Glu Ala Glu Leu Val Glu Met Asp 50 55 60 Gly Glu Pro Asp His Val His Leu Leu Ile Asn Tyr Pro Pro Lys Leu 65 70 75 80 Ala Ile Ser Ser Leu Val Asn Ser Leu Lys Gly Val Ser Gly Arg Leu 85 90 95 Leu Arg Arg Asp Arg Pro Asp Ile Ala Val Arg Tyr Tyr Tyr Lys Gly 100 105 110 Val Leu Trp Ser Pro Gly Tyr Phe Ala Ser Ser Cys Gly Gly Ala Pro 115 120 125 Ile Ser Ala Ile Arg Gln Tyr Ile Glu Gln Gln Gln Thr Pro Gly * 130 135 140 <210> 1621 <211> 383 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(556..1704) <400> 1621 Met Arg Arg Phe Ala Gly Ala Cys Arg Phe Val Phe Asn Arg Ala Leu 1 5 10 15 Ala Leu Gln Asn Glu Asn His Glu Ala Gly Asn Lys Tyr Ile Pro Tyr 20 25 30 Gly Lys Met Ala Ser Trp Leu Val Glu Trp Lys Asn Ala Thr Glu Thr 35 40 45 Gln Trp Leu Lys Asp Ala Pro Ser Gln Pro Leu Gln Gln Ser Leu Lys 50 55 60 Asp Leu Glu Arg Ala Tyr Lys Asn Phe Phe Arg Lys Arg Ala Ala Phe 65 70 75 80 Pro Arg Phe Lys Lys Arg Gly Gln Asn Asp Ala Phe Arg Tyr Pro Gln 85 90 95 Gly Val Lys Leu Asp Gln Glu Asn Ser Arg Ile Phe Leu Pro Lys Leu 100 105 110 Gly Trp Met Arg Tyr Arg Asn Ser Arg Gln Val Thr Gly Val Val Lys 115 120 125 Asn Val Thr Ala Ser Gln Ser Cys Gly Lys Trp Tyr Ile Ser Ile Gln 130 135 140 Thr Glu Asn Glu Val Ser Thr Pro Val His Pro Ser Ala Leu Met Val 145 150 155 160 Gly Leu Asp Ala Gly Val Ala Lys Leu Ala Thr Leu Ser Asp Gly Thr 165 170 175 Val Phe Gly Pro Val Asn Ser Phe Gln Lys Asn Gln Lys Thr Leu Ala 180 185 190 Arg Leu Gln Arg Gln Leu Ser Arg Lys Val Lys Phe Ser Asn Asn Trp 195 200 205 Gln Lys Gln Lys Arg Lys Ile Gln Arg Leu His Ser Cys Ile Ala Asn 210 215 220 Ile Cys Arg Asp Tyr Leu His Lys Val Thr Thr Thr Val Ser Lys Asn 225 230 235 240 His Ala Met Ile Val Ile Glu Asp Leu Lys Val Ser Asn Met Ser Lys 245 250 255 Ser Ala Ala Gly Thr Val Ser Gln Pro Gly Arg Asn Val Arg Ala Lys 260 265 270 Ser Gly Leu Asn Arg Ser Ile Leu Asp Gln Gly Trp Tyr Glu Met Arg 275 280 285 Arg Gln Leu Glu Tyr Lys Gln Leu Trp Arg Gly Gly Gln Val Leu Ala 290 295 300 Val Pro Pro Ala Tyr Thr Ser Gln Arg Cys Ala Cys Cys Gly His Thr 305 310 315 320 Ala Lys Glu Asn Arg Leu Ser Gln Ser Lys Phe Arg Cys Gln Ala Cys 325 330 335 Gly Tyr Thr Ala Asn Ala Asp Val Asn Gly Ala Arg Asn Ile Leu Ala 340 345 350 Ala Gly His Ala Val Leu Ala Cys Gly Glu Met Val Gln Ser Gly Arg 355 360 365 Pro Leu Lys Gln Glu Pro Thr Glu Met Ile Gln Ala Thr Ala * 370 375 380 <210> 1622 <211> 1713 <212> DNA <213> Escherichia coli O157:H7 <400> 1622 atgagattga tgacaaatgc aagactgcct gattcgccac acttagttgt actatagcct 60 ttaccaggcg taataattcg ttttcacctg attttggccc actttgtgaa ttggcgatat 120 atttatccag ttgggagaag tgacaatgac tccaggtaga aaccggtatg aagcgcccga 180 ctcactgtca aaaccgattg ttgagagtaa tgacactccg gcgaacagta cacagtttac 240 tctggagcca ttctcaatct tcaagtggga tacctaataa cttgtcaggg aagttatcaa 300 tatctgtttg ttacttatta ccgtatttat taacaataat gatactttct aacatgcgta 360 aaggtcttcg taataaaatg agctaaattt gatagtgaat atattctgca aagattaaat 420 tgtatcttgt taactcacaa tacaaggaat catttatgcc aaatacatct attcacttat 480 ctcgctgtaa tattttacaa aataataaat tgcaaccaac agaaatttac aaagaatcac 540 aacaaaccgc caaacttgag tttttttgcg atgagtttct aaaaatatct caaagtagat 600 acgggttatc aacctcaaca gacagcatag ctaatttatt ggcttttttc acgaaagcct 660 cagatgcaat tgatagtatc aagacccaaa aaattgacgt tcacagttat ggtttcgtac 720 caataagaca ttttgtcgaa catgtcataa cgtataaaaa tgaatttgca gcggattatg 780 aaccctatac ccttaccttt acccgaggtg aaaacaacga aggtattttg agtgtcgaaa 840 gcaaagaagg gtttatttca caaagaacaa taaacttaaa tgaatatgaa actgcaatta 900 acatcatcaa tgaacatgtt ataaaagaaa atatccacaa cacggtccag tcaccgacag 960 aaaaatacat ttcaaaaata aacagctctg ataaacctta taaaaccagc agtaaggaaa 1020 gtattaaaag tcaactttac agcgatcaaa gaaatataca gacctgctac tacattctga 1080 gaaaaaatac agaatggtac aaatacgcat cctccgagga acgctatgat aaattcaaga 1140 attcttctaa ggaaattaaa aatacctaca agcaaattgt acaagcgcag aaaaaattga 1200 accaaatgaa atacatcaat aaattaagtg gtgagcttat cgatatcacc gacaaaaagt 1260 tagcaccatt aataaatgat agtttcagct atacacgaga tttctttgct tactcaaaac 1320 aggaaaaaaa tatcttcaca tttgataatt ctaagtttgt agatccaaag gaaaaagaag 1380 gtttaatggt acaacacagc aatgggcaac tggttattac tggtaaatat tgccctgaag 1440 gtgtgcaaac agcattcacc caagaacaat atgataaatt aataagatac attaatattt 1500 tctttacctt tccgaaatta gaataatact ttacagtata aactgcatta caatttatta 1560 ttgagaccta ttcatactgt ttaaagaata acaatgccca gtgttagctt ttttaacgaa 1620 tgagttttac gaaaattatg ttggcatctt ttttacagga cgcaccggtt aatgaaaaga 1680 ataaccggta gtagcattat ttcgctttag cag 1713 <210> 1623 <211> 357 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(456..1526) <400> 1623 Met Pro Asn Thr Ser Ile His Leu Ser Arg Cys Asn Ile Leu Gln Asn 1 5 10 15 Asn Lys Leu Gln Pro Thr Glu Ile Tyr Lys Glu Ser Gln Gln Thr Ala 20 25 30 Lys Leu Glu Phe Phe Cys Asp Glu Phe Leu Lys Ile Ser Gln Ser Arg 35 40 45 Tyr Gly Leu Ser Thr Ser Thr Asp Ser Ile Ala Asn Leu Leu Ala Phe 50 55 60 Phe Thr Lys Ala Ser Asp Ala Ile Asp Ser Ile Lys Thr Gln Lys Ile 65 70 75 80 Asp Val His Ser Tyr Gly Phe Val Pro Ile Arg His Phe Val Glu His 85 90 95 Val Ile Thr Tyr Lys Asn Glu Phe Ala Ala Asp Tyr Glu Pro Tyr Thr 100 105 110 Leu Thr Phe Thr Arg Gly Glu Asn Asn Glu Gly Ile Leu Ser Val Glu 115 120 125 Ser Lys Glu Gly Phe Ile Ser Gln Arg Thr Ile Asn Leu Asn Glu Tyr 130 135 140 Glu Thr Ala Ile Asn Ile Ile Asn Glu His Val Ile Lys Glu Asn Ile 145 150 155 160 His Asn Thr Val Gln Ser Pro Thr Glu Lys Tyr Ile Ser Lys Ile Asn 165 170 175 Ser Ser Asp Lys Pro Tyr Lys Thr Ser Ser Lys Glu Ser Ile Lys Ser 180 185 190 Gln Leu Tyr Ser Asp Gln Arg Asn Ile Gln Thr Cys Tyr Tyr Ile Leu 195 200 205 Arg Lys Asn Thr Glu Trp Tyr Lys Tyr Ala Ser Ser Glu Glu Arg Tyr 210 215 220 Asp Lys Phe Lys Asn Ser Ser Lys Glu Ile Lys Asn Thr Tyr Lys Gln 225 230 235 240 Ile Val Gln Ala Gln Lys Lys Leu Asn Gln Met Lys Tyr Ile Asn Lys 245 250 255 Leu Ser Gly Glu Leu Ile Asp Ile Thr Asp Lys Lys Leu Ala Pro Leu 260 265 270 Ile Asn Asp Ser Phe Ser Tyr Thr Arg Asp Phe Phe Ala Tyr Ser Lys 275 280 285 Gln Glu Lys Asn Ile Phe Thr Phe Asp Asn Ser Lys Phe Val Asp Pro 290 295 300 Lys Glu Lys Glu Gly Leu Met Val Gln His Ser Asn Gly Gln Leu Val 305 310 315 320 Ile Thr Gly Lys Tyr Cys Pro Glu Gly Val Gln Thr Ala Phe Thr Gln 325 330 335 Glu Gln Tyr Asp Lys Leu Ile Arg Tyr Ile Asn Ile Phe Phe Thr Phe 340 345 350 Pro Lys Leu Glu * 355 <210> 1624 <211> 1657 <212> DNA <213> Escherichia coli O157:H7 <400> 1624 agcatctgtt ttatttgtta cgtcgttagt caccagccct gacactacgc agcgcaaaaa 60 agctgctcaa tgtcagggct gaatttgtta aatatttgtc ccgatcgata tgagcgattt 120 ttggtattgt ttgcccatga tgttatgtac aacatgctcc aggataaccc tgtagtggag 180 caaagatatg acaatttcaa attcgaattt attgaaaccg tttattactg gtactgagtt 240 gccacctttt aaagaggatg tcttttctaa aacagaagaa caatttaaaa aaagcaccta 300 tggcaaatcg cttttcattt ccggaaatga aaacttagta aacatttcag cggaaaaaat 360 cgatgaaata aaaaatagca aaaatttctt ttcaaacatt gtaaatataa taattttact 420 cattaagcat cctgataaaa ttctgcccat tcttcatggt tgtcctgtag agtcgatcga 480 agtcattaag aatgcgaaac gaacgggaca atggtcatat gagatgactg ataagaacgg 540 gcagagtatt gaagtgtcct atattttcac tgataccata gatgataaat ctgatggaaa 600 attatgctta aaaatctgta actcctgcaa ccaaaatgat tctagtacac atgaatataa 660 aatagatcat caacagttga aaaatcacat aaggcaactt gaggagtggg cccttcttga 720 aaagttttat gataacaacg cttattattc taaacgtaca aaacaattag agaagaaaat 780 tgccgatgcg gggtttataa caaggaaggt taaagccgag aactttaatg taaaagagtt 840 taaagacgat atagcctcga tgctttgtga acagcccccc atgcgtacac accagatttc 900 ttcatccgga tacgtatctg ccgataaact gcacaaactc tataagacaa atttggaaga 960 cgcgcagaga gatctgaaaa caacaccggt tgacatcgat ggtgttagtc taaaatcaat 1020 aactcgggaa aaaattgcgg aagaaattgc gaaaaaaact gcggaaataa ttgcgaaaca 1080 aaatgcgaag agcattgagg agaagaatat tgaaaaaaac aagaaacaaa caaattctga 1140 ggataatttt gtcttaaaat tctcaccgga agaaatcaat gagatgctcc tggattacag 1200 cgatgaagaa caaaaaaaat taagaccttt tttcactagt gatcacatct attgtttgtt 1260 tgatgctttt agtcagggtt tgcataatgt tgctcgtaat ggcagtccac ggtatgcagg 1320 tttactacgt caaatagcat ccaagtctgc gatattacaa gattttgatc aacaattgtt 1380 ctggcgcacg tttacaggag gggtcctcca tcgacatatc tctgtgaaga gcgagccaga 1440 aaagacagat gtatggcgat tcagtagcca atttgatttt ccacatataa atgaaaacgg 1500 agagttgtcc agaacggtac tcatgttcga gggggttgct gaaagcaact ttaaagatat 1560 cgccaatcat tccagcgaat gtttttctta ccgttgttat gccgccccgc tggatgcgaa 1620 tgctaaaaaa tagtgacgcc ggagtttgaa gtttcag 1657 <210> 1625 <211> 482 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(188..1633) <400> 1625 Met Thr Ile Ser Asn Ser Asn Leu Leu Lys Pro Phe Ile Thr Gly Thr 1 5 10 15 Glu Leu Pro Pro Phe Lys Glu Asp Val Phe Ser Lys Thr Glu Glu Gln 20 25 30 Phe Lys Lys Ser Thr Tyr Gly Lys Ser Leu Phe Ile Ser Gly Asn Glu 35 40 45 Asn Leu Val Asn Ile Ser Ala Glu Lys Ile Asp Glu Ile Lys Asn Ser 50 55 60 Lys Asn Phe Phe Ser Asn Ile Val Asn Ile Ile Ile Leu Leu Ile Lys 65 70 75 80 His Pro Asp Lys Ile Leu Pro Ile Leu His Gly Cys Pro Val Glu Ser 85 90 95 Ile Glu Val Ile Lys Asn Ala Lys Arg Thr Gly Gln Trp Ser Tyr Glu 100 105 110 Met Thr Asp Lys Asn Gly Gln Ser Ile Glu Val Ser Tyr Ile Phe Thr 115 120 125 Asp Thr Ile Asp Asp Lys Ser Asp Gly Lys Leu Cys Leu Lys Ile Cys 130 135 140 Asn Ser Cys Asn Gln Asn Asp Ser Ser Thr His Glu Tyr Lys Ile Asp 145 150 155 160 His Gln Gln Leu Lys Asn His Ile Arg Gln Leu Glu Glu Trp Ala Leu 165 170 175 Leu Glu Lys Phe Tyr Asp Asn Asn Ala Tyr Tyr Ser Lys Arg Thr Lys 180 185 190 Gln Leu Glu Lys Lys Ile Ala Asp Ala Gly Phe Ile Thr Arg Lys Val 195 200 205 Lys Ala Glu Asn Phe Asn Val Lys Glu Phe Lys Asp Asp Ile Ala Ser 210 215 220 Met Leu Cys Glu Gln Pro Pro Met Arg Thr His Gln Ile Ser Ser Ser 225 230 235 240 Gly Tyr Val Ser Ala Asp Lys Leu His Lys Leu Tyr Lys Thr Asn Leu 245 250 255 Glu Asp Ala Gln Arg Asp Leu Lys Thr Thr Pro Val Asp Ile Asp Gly 260 265 270 Val Ser Leu Lys Ser Ile Thr Arg Glu Lys Ile Ala Glu Glu Ile Ala 275 280 285 Lys Lys Thr Ala Glu Ile Ile Ala Lys Gln Asn Ala Lys Ser Ile Glu 290 295 300 Glu Lys Asn Ile Glu Lys Asn Lys Lys Gln Thr Asn Ser Glu Asp Asn 305 310 315 320 Phe Val Leu Lys Phe Ser Pro Glu Glu Ile Asn Glu Met Leu Leu Asp 325 330 335 Tyr Ser Asp Glu Glu Gln Lys Lys Leu Arg Pro Phe Phe Thr Ser Asp 340 345 350 His Ile Tyr Cys Leu Phe Asp Ala Phe Ser Gln Gly Leu His Asn Val 355 360 365 Ala Arg Asn Gly Ser Pro Arg Tyr Ala Gly Leu Leu Arg Gln Ile Ala 370 375 380 Ser Lys Ser Ala Ile Leu Gln Asp Phe Asp Gln Gln Leu Phe Trp Arg 385 390 395 400 Thr Phe Thr Gly Gly Val Leu His Arg His Ile Ser Val Lys Ser Glu 405 410 415 Pro Glu Lys Thr Asp Val Trp Arg Phe Ser Ser Gln Phe Asp Phe Pro 420 425 430 His Ile Asn Glu Asn Gly Glu Leu Ser Arg Thr Val Leu Met Phe Glu 435 440 445 Gly Val Ala Glu Ser Asn Phe Lys Asp Ile Ala Asn His Ser Ser Glu 450 455 460 Cys Phe Ser Tyr Arg Cys Tyr Ala Ala Pro Leu Asp Ala Asn Ala Lys 465 470 475 480 Lys * <210> 1626 <211> 1645 <212> DNA <213> Escherichia coli O157:H7 <400> 1626 gaccaacgat atttctggtc aaacttacaa tactttccat cactacaacg acgccaccta 60 tgctgatgac gtttactatg atggttatgt aggctggaac aactatgccg ctgatagcta 120 ttacaacggc gatatctacc cggtcattaa taacgctacc gttaacggcg tgatttctac 180 ctactatctg gacgacggta tttctaccaa taccaacgcc aatagtctga caatcaaaaa 240 cagcactatt cacggtatga ttacctctga gtgcatgact actgattgtg ctgatgaccg 300 tgctactggt tatgtttatg atcgtctgac actgagcgtt gataattcaa cgatcgatga 360 caactacgag cattatactt acaacggtac ctataataat gccgctgaca ctcatgttgt 420 agatgtttac gatatgggta ctgctattac actggatcag gaagttgatc tgtccatcac 480 taataactct catgtagcag gtattacgct gactcagggt tatgagtggg aagatattga 540 cgacaacaca gtcagcactg gcgtaaacag cagcgaagtg tttaataaca ctattactgt 600 taaagattct actgtgacct ctggttcatg gactgatgaa ggtactactg gttggtttgg 660 ccatactggt aatgccagca actatagcaa cacgctgact gcagacgatg ttgcaattgc 720 cgcaatcgca aatccgtatg ctgataatgc gatgcagact acagtaactt tagacaactc 780 aacactgatg ggtgatgttg ttttctccag taatttcgat gaaaacttct tcccgcaagg 840 tgctaacagc tatcgcgatg ctgatggtga tgtagatacc aacggttggg atggcacaga 900 ccgtatggat gtgactctga acaacggcag caagtgggtt ggcgctgcaa tgtctgttca 960 tatggttgat gaagatggtg atggttctta cgacggatat gctgttggta ctgaagcaac 1020 tgcaactctg ctcgatattg cagctaacag cctgtggcct tcatcaactg tcggtgttga 1080 taacatcaat actcaatatg acgaaaatgg ccatatcgta ggaaacgaag tttaccagag 1140 cggtttgttt aatgtgactt tgaacggtgg ttcagagtgg gatacaacaa aatcttctct 1200 gattgatact ttaagtatta acagcggttc ccaagttaat gttgcagact ctcgtctgat 1260 ctctgacact gtctctctga ctggcggttc taacctgaac atcggtgaag acggtcatgt 1320 agcgactaat accctgacca tcgacaatag taccgttaaa atgtctgatg atgtttctgc 1380 gggctggggt ttagaagatg ctgcactgta cgcaaatacc atcaccgtaa ctaacgacgg 1440 tctgttggat attaacgttg atcagttcga tgctaacccg ttccaggccg ataccctgaa 1500 tctgaccagt accactgata ctaacggcaa cattcacgct ggtgtattcg atatccatag 1560 cagtgattac gtaatggata ccgatctggt caacgatcgt accaacgata ctaccaagtc 1620 aaactacggt tatggcttaa tcgca 1645 <210> 1627 <211> 1545 <212> DNA <213> Escherichia coli O157:H7 <400> 1627 ggagacatcc agcgatgcta gcttgttata atcaagatta agaaatttca gtttataact 60 atcagaaata ttaatttttt tagattatta ttttgcgctt ccagattaac caatgaatgc 120 tgatttttta aatctaaact ttccagatta ttatgatcaa tataaatgtt ttccagattt 180 gattcatttg gaaaggttat cgtgttaatt ttattaaagc tgaggttgat attaacgaga 240 ctggcattgt cagtaaagtc aagacaagtt agacaattgt tttccagatt taacgtatta 300 actgtcgagg ggataggcgg taactcactc aaatcaagat atgacaaatc aagagatgcc 360 atgttcgaat tgtaagcttc tttaattcgc tccacggcaa ttgctctttc ttcaccatta 420 ttaagcgact tattacccca ttgttctagt cgttcacaaa aattgctgga gatggtttct 480 ttgttaggta atgcgttatt aaattgataa ctggcattat tttttacaca agctgtatta 540 atattggtca taatcactca tcaataaata ttatagtaag atgtccccgg gggtatggaa 600 taatattaat tgaggtgaat gaccagaaat atcaaaaatt gctcattttt acttaaggag 660 tcatacagca gcacttaaat caaaaaccag cccagagaag ggctggtcag gagaggatgt 720 tagaactgat aggtaatgcc cgtagcgacg atgttatcgg tgcgaatatc tacggcacgg 780 gtaaagtcgc tttcatcaat caggttgatt ttataatcaa cataggtcga catatttttg 840 ttgaagaaat acgtcgcacc aacgtcgata tactcaatca tgtcctgatc gccgtagcgg 900 cccagatcta tgcctttcga tttcaggtaa gcgagtgagg ggcgcaagcc gaagtcgaat 960 tgatattgcg ccaccacttc aaaactttgt gctttgttag aaatataacc atcgccatag 1020 gtggtcatgt ttaatgtttc agcgtaatta gctgcaaagt agatgttgtt ggcatcatat 1080 tttatacctg tagcccacag ttctgcattc ttaccggagg cattgagagg attagcagcg 1140 gctctttcct gcgcatttgt ccgatcggat ttggtataca ccgctccgat accaaagcca 1200 tcataaacat aagttgagga gataccgaaa ccgtcaccgt tggcacgcgt gtagtcagca 1260 ccataaagat gactgttgtc agtacgttca tttttgcctt gatattgcgc ggcaaagttc 1320 agcccttcaa ttaagccaaa gaaatcgtag ttgcgatagg ttgctacacc ggtggtacgg 1380 tatgtcatga agacatcttt ctgactccag gtatcgccac caaattctgg caacatatca 1440 gtccatgaac caatgtcata gccgacaccg tagttacggc catagtccag agagccaaat 1500 tcactaattt ttaaaccagc ataggccaga cgggtcttgt tgtcg 1545 <210> 1628 <211> 168 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(48..551) <400> 1628 Met Thr Asn Ile Asn Thr Ala Cys Val Lys Asn Asn Ala Ser Tyr Gln 1 5 10 15 Phe Asn Asn Ala Leu Pro Asn Lys Glu Thr Ile Ser Ser Asn Phe Cys 20 25 30 Glu Arg Leu Glu Gln Trp Gly Asn Lys Ser Leu Asn Asn Gly Glu Glu 35 40 45 Arg Ala Ile Ala Val Glu Arg Ile Lys Glu Ala Tyr Asn Ser Asn Met 50 55 60 Ala Ser Leu Asp Leu Ser Tyr Leu Asp Leu Ser Glu Leu Pro Pro Ile 65 70 75 80 Pro Ser Thr Val Asn Thr Leu Asn Leu Glu Asn Asn Cys Leu Thr Cys 85 90 95 Leu Asp Phe Thr Asp Asn Ala Ser Leu Val Asn Ile Asn Leu Ser Phe 100 105 110 Asn Lys Ile Asn Thr Ile Thr Phe Pro Asn Glu Ser Asn Leu Glu Asn 115 120 125 Ile Tyr Ile Asp His Asn Asn Leu Glu Ser Leu Asp Leu Lys Asn Gln 130 135 140 His Ser Leu Val Asn Leu Glu Ala Gln Asn Asn Asn Leu Lys Lys Leu 145 150 155 160 Ile Phe Leu Ile Val Ile Asn * 165 <210> 1629 <211> 1527 <212> DNA <213> Escherichia coli O157:H7 <400> 1629 ttaatctctt ccacgcagag gcgccgcaag gcgccttatt ttttacttca ctgtattttt 60 agcagacaac ataatctcca tcgcctgttg gcgatattta tctgccgtat ctggctccat 120 taatgcaatg atccccacag ccctgggggt gtcttcaaga taaacactga tggttctttt 180 ctgctgacca tcaaaattta tcaacacatc ctgatactta caggtgaaat gtttggcatt 240 acaatcatga aactggaagg tttcttcatt gtattgatcc ttgagattgt ctcgctgcat 300 cttctttaac tcttccagcg agtcatcggc gctacgtcct gcgggcaggc ggaaagcaga 360 aataaagacg ctattatctt cacttcttat atcaatggtt ttatcagtac taatagaaac 420 cgtattccag tgtcggtttg ggacagtcac ggaaatagct gccttctcaa acgtatagtg 480 ccacggggtg aacagacgaa acgtattgcc gacgttggat aaaagcagga ctcccaatac 540 ccaacagcac ccgcgagtaa aactggcgaa gttacgcgtt tttttagtga atgtgcacag 600 aatacctgac acaagcacgg gaagtaataa cggtccaaga agtactgaac cgatatactc 660 gccaaccatc cctggatctc cagtaagcaa gttactgtgc tgaagatgac taagaaaaac 720 agttattatc catagtatta ataagataac gtatctcata tcaatccatt attattaaca 780 tgcacatcag atcattgacg agcagaaagc atcattttca ttacttcttc ttgatattcg 840 tccaaataat ctgggtcgat agctgcgacc agttgtatca aattagtgtt atccagtaga 900 gtcatgaaaa tagcatgtct tactttgcca tcactcattg tttgcactcc ttcctgataa 960 gcgcaggcaa atccctgaac atcacaaaca tgcatttctg cagttccgtt ttgagtcgcg 1020 gtaagttcct cgattgaatg cacaccgagt tcattttgtg agaaggcaac aatagctaaa 1080 atagcatggg catcccgggt caccagggtt ggtccttgtt ttactatatt ggcaacccac 1140 tgtttgctcg gaaccgtgac ggtgatacct ggctccggga aagtataatc ccatatgctg 1200 tgtcgttccc acaccgtata gctgctatag ataagaaata atcccattaa ccaacaagtg 1260 ccgcgaataa agctgcggct gcttcttttt tttatcgtta tacagatgat tgtggcgata 1320 ataaatgata aggcaagtgg gttaaaaaat acgttagcaa aatataaaat catttcaccc 1380 gcgttgccag ataaaagaaa tttgtagcgg aaatggttaa cggctataag taataaatat 1440 ataaataaaa gaataatatt ctgcatgaat acgtccatgt ataaaaaagg ggaatttaat 1500 tcccctttta acgcatggca gatactt 1527 <210> 1630 <211> 239 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43..759) <400> 1630 Met Arg Tyr Val Ile Leu Leu Ile Leu Trp Ile Ile Thr Val Phe Leu 1 5 10 15 Ser His Leu Gln His Ser Asn Leu Leu Thr Gly Asp Pro Gly Met Val 20 25 30 Gly Glu Tyr Ile Gly Ser Val Leu Leu Gly Pro Leu Leu Leu Pro Val 35 40 45 Leu Val Ser Gly Ile Leu Cys Thr Phe Thr Lys Lys Thr Arg Asn Phe 50 55 60 Ala Ser Phe Thr Arg Gly Cys Cys Trp Val Leu Gly Val Leu Leu Leu 65 70 75 80 Ser Asn Val Gly Asn Thr Phe Arg Leu Phe Thr Pro Trp His Tyr Thr 85 90 95 Phe Glu Lys Ala Ala Ile Ser Val Thr Val Pro Asn Arg His Trp Asn 100 105 110 Thr Val Ser Ile Ser Thr Asp Lys Thr Ile Asp Ile Arg Ser Glu Asp 115 120 125 Asn Ser Val Phe Ile Ser Ala Phe Arg Leu Pro Ala Gly Arg Ser Ala 130 135 140 Asp Asp Ser Leu Glu Glu Leu Lys Lys Met Gln Arg Asp Asn Leu Lys 145 150 155 160 Asp Gln Tyr Asn Glu Glu Thr Phe Gln Phe His Asp Cys Asn Ala Lys 165 170 175 His Phe Thr Cys Lys Tyr Gln Asp Val Leu Ile Asn Phe Asp Gly Gln 180 185 190 Gln Lys Arg Thr Ile Ser Val Tyr Leu Glu Asp Thr Pro Arg Ala Val 195 200 205 Gly Ile Ile Ala Leu Met Glu Pro Asp Thr Ala Asp Lys Tyr Arg Gln 210 215 220 Gln Ala Met Glu Ile Met Leu Ser Ala Lys Asn Thr Val Lys * 225 230 235 <210> 1631 <211> 225 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(792..1466) <400> 1631 Met Gln Asn Ile Ile Leu Leu Phe Ile Tyr Leu Leu Leu Ile Ala Val 1 5 10 15 Asn His Phe Arg Tyr Lys Phe Leu Leu Ser Gly Asn Ala Gly Glu Met 20 25 30 Ile Leu Tyr Phe Ala Asn Val Phe Phe Asn Pro Leu Ala Leu Ser Phe 35 40 45 Ile Ile Ala Thr Ile Ile Cys Ile Thr Ile Lys Lys Arg Ser Ser Arg 50 55 60 Ser Phe Ile Arg Gly Thr Cys Trp Leu Met Gly Leu Phe Leu Ile Tyr 65 70 75 80 Ser Ser Tyr Thr Val Trp Glu Arg His Ser Ile Trp Asp Tyr Thr Phe 85 90 95 Pro Glu Pro Gly Ile Thr Val Thr Val Pro Ser Lys Gln Trp Val Ala 100 105 110 Asn Ile Val Lys Gln Gly Pro Thr Leu Val Thr Arg Asp Ala His Ala 115 120 125 Ile Leu Ala Ile Val Ala Phe Ser Gln Asn Glu Leu Gly Val His Ser 130 135 140 Ile Glu Glu Leu Thr Ala Thr Gln Asn Gly Thr Ala Glu Met His Val 145 150 155 160 Cys Asp Val Gln Gly Phe Ala Cys Ala Tyr Gln Glu Gly Val Gln Thr 165 170 175 Met Ser Asp Gly Lys Val Arg His Ala Ile Phe Met Thr Leu Leu Asp 180 185 190 Asn Thr Asn Leu Ile Gln Leu Val Ala Ala Ile Asp Pro Asp Tyr Leu 195 200 205 Asp Glu Tyr Gln Glu Glu Val Met Lys Met Met Leu Ser Ala Arg Gln 210 215 220 * <210> 1632 <211> 1507 <212> DNA <213> Escherichia coli O157:H7 <400> 1632 cgttcgtgcc gttccactac tggcacggct tcgctaatca ttattctgag gcaaaggcat 60 agccttcatc ttcccagccg gttatcccgc cgagcatgat tttaaccggc tttccgagtc 120 gagccagttt gagtgccgca cggtctgcac cgttacaatg tggccccgcg caatacacca 180 caaatagcgt atcgtcgggc cattcggcca ttctttctgc ggtcatttgc ttatggggta 240 aatggagagc gcctgggata tgccgacgcg cgaagtcctc ttcacgtcca accacatgaa 300 gtaaaacgaa atcatcgcca atataagcca gagagtcatg aacatcggcg caatctgttt 360 cgacactcaa gcgcgcgaga aaatgcgcct cagcaacttc tggcttcgct gtggtaaatt 420 cagtgacata acgcatattg ctttgtcctt ttggtttgtt gtgttaacaa taatgtaact 480 aatctacctt tcactgaccg cctctcgata tgccagaaat gagcaaaatg atgacaacgt 540 tacaacgtcc gctggtcatt gcactggcat atgacgggct atgtactttt gaatttggcg 600 ttgccgttga aatattcggc ctgccacgac cggaactggg cgataactgg tatcgttttg 660 ctgttgctgc ggtagaacca ggtgcgctac aagccaccgg ggggatccac gtggttgctg 720 atggtggact ggagttattg cccaacgccg atatgattat tattcctggc tggcgcggaa 780 tagatgccaa agtgccggag atgctatgcc agtcattgcg cgaggcacac cagcgcggta 840 ctcgcctggt atcaatatgc tctggcgtgt ttgtccttgc tgctgcgggc cttcttcatc 900 agcgaaaagc aaccacccac tggcgctaca ctgaacaact ccagcaccgt tacccttcaa 960 tcagcgtaag tgacaatgtg ttatatcagg atgaaggaca agtgatgacc tccgccggaa 1020 gcgccgcggg gatcgatctg tgtttacata tcgtgcgcaa agattttggt catgagattg 1080 ctaataatgt cgcccggcga ctggtcattc agccacatcg ccagggggat caaccacaaa 1140 atctgacgcg cccaatggcc tcaccgcgtg aaagccagac gttaggtgcc ttattcgact 1200 ttttgcagca gaatctggca caaacacata ctgtgtcttc cctcgccgaa cgggtaaata 1260 tgagtccgcg cactttttta agacgttttg aggcgttaac tggcatgacg cccgcccgct 1320 ggctgctcaa tgagcgctta atacgagtac aggattatct gcaaaattcg gtttttaaca 1380 tcgagaaaat tgccgagctg acgggttttg gcaattcagc gttattgcgt catcactttc 1440 accaacgttt tttattatct ccttcgcaat atcgcaaaaa cagccgttcc ccatcacaat 1500 aatcgcc 1507 <210> 1633 <211> 95 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(133..417) <400> 1633 Val Pro His Gly Leu His Arg Tyr Asn Val Ala Pro Arg Asn Thr Pro 1 5 10 15 Gln Ile Ala Tyr Arg Arg Ala Ile Arg Pro Phe Phe Leu Arg Ser Phe 20 25 30 Ala Tyr Gly Val Asn Gly Glu Arg Leu Gly Tyr Ala Asp Ala Arg Ser 35 40 45 Pro Leu His Val Gln Pro His Glu Val Lys Arg Asn His Arg Gln Tyr 50 55 60 Lys Pro Glu Ser His Glu His Arg Arg Asn Leu Phe Arg His Ser Ser 65 70 75 80 Ala Arg Glu Asn Ala Pro Gln Gln Leu Leu Ala Ser Leu Trp * 85 90 <210> 1634 <211> 325 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(528..1502) <400> 1634 Met Met Thr Thr Leu Gln Arg Pro Leu Val Ile Ala Leu Ala Tyr Asp 1 5 10 15 Gly Leu Cys Thr Phe Glu Phe Gly Val Ala Val Glu Ile Phe Gly Leu 20 25 30 Pro Arg Pro Glu Leu Gly Asp Asn Trp Tyr Arg Phe Ala Val Ala Ala 35 40 45 Val Glu Pro Gly Ala Leu Gln Ala Thr Gly Gly Ile His Val Val Ala 50 55 60 Asp Gly Gly Leu Glu Leu Leu Pro Asn Ala Asp Met Ile Ile Ile Pro 65 70 75 80 Gly Trp Arg Gly Ile Asp Ala Lys Val Pro Glu Met Leu Cys Gln Ser 85 90 95 Leu Arg Glu Ala His Gln Arg Gly Thr Arg Leu Val Ser Ile Cys Ser 100 105 110 Gly Val Phe Val Leu Ala Ala Ala Gly Leu Leu His Gln Arg Lys Ala 115 120 125 Thr Thr His Trp Arg Tyr Thr Glu Gln Leu Gln His Arg Tyr Pro Ser 130 135 140 Ile Ser Val Ser Asp Asn Val Leu Tyr Gln Asp Glu Gly Gln Val Met 145 150 155 160 Thr Ser Ala Gly Ser Ala Ala Gly Ile Asp Leu Cys Leu His Ile Val 165 170 175 Arg Lys Asp Phe Gly His Glu Ile Ala Asn Asn Val Ala Arg Arg Leu 180 185 190 Val Ile Gln Pro His Arg Gln Gly Asp Gln Pro Gln Asn Leu Thr Arg 195 200 205 Pro Met Ala Ser Pro Arg Glu Ser Gln Thr Leu Gly Ala Leu Phe Asp 210 215 220 Phe Leu Gln Gln Asn Leu Ala Gln Thr His Thr Val Ser Ser Leu Ala 225 230 235 240 Glu Arg Val Asn Met Ser Pro Arg Thr Phe Leu Arg Arg Phe Glu Ala 245 250 255 Leu Thr Gly Met Thr Pro Ala Arg Trp Leu Leu Asn Glu Arg Leu Ile 260 265 270 Arg Val Gln Asp Tyr Leu Gln Asn Ser Val Phe Asn Ile Glu Lys Ile 275 280 285 Ala Glu Leu Thr Gly Phe Gly Asn Ser Ala Leu Leu Arg His His Phe 290 295 300 His Gln Arg Phe Leu Leu Ser Pro Ser Gln Tyr Arg Lys Asn Ser Arg 305 310 315 320 Ser Pro Ser Gln * <210> 1635 <211> 1427 <212> DNA <213> Escherichia coli O157:H7 <400> 1635 catgttctta atggatatcc aggtacacca gaaggtcgat ttggaaaaat ggattccgat 60 ggtaagaata tcatatattc tgaatgtaat gttttaccca caacttttga gattcgatag 120 gtgtagaaca tgagaaactc actaatatta cttattatga tattgtttac aatatcacac 180 tcagtatttg gaaaagaaaa tccagtggaa atttaagtaa atagtcgtga aatggctttg 240 gaattatcat atgtttacat taaatatgta tacgggaaag aaaaagcaga atttcagaaa 300 ccatatagta ttacagatga caataattgt tggaaaatcg agggaaaaca accgaagaat 360 tcaggaggaa attttacaat gctaatagcg aaaaaagatg ggcaagtgtt gaatgtaata 420 cacacaaaat aatccactgt acagtcgatt caaatatttt accaaggtgt gtttcgtaac 480 aattttgtgt acaatatgac tctacatatc gacgaaaaaa ccacttgatt tgacaggaat 540 acattcaaaa aatttctttt ttcatttcag gagcgatttt catctgttac ttgaagtatc 600 tgtgagatta agtgactccc cctaacgtcg tactaaatag taattactgg ccataccggg 660 agcagtattc ggcgctcccc acatgcagca gaataaccgc atcagcgaag atgtattttt 720 actatcacaa tgtgtacgga cggtttatgg aaaagaatga acattagata cgcgatgcgg 780 cggcaggtta cacggttatc actacgatag ccaatactgg ctggtgcatt accgccgtga 840 acaataggac gccgtactgc tggaaatttc ttacctttat aactccccgc gccgccgtat 900 cgggaaacgg gaagcaatca agatgaggct gatataatgt gcggaatgcc tgagtatttt 960 tagaataggg gggtaatatg tttgatagaa tatatcttgg tgatcgagca ataaaaaaat 1020 tgaatttgat ttatggagta aacaaattag aattcaggtt aatttaatct caaggatagc 1080 ctatggtaca acagaatgga atttttatga taatgaagac ttagaagatg gttatttggt 1140 attttcaggt gttagtttct tcaatataac tcctaatggc tctattccaa atgattatat 1200 aatttcaata attacagata atgtcaatgt tgaatatttt gaatcaacta tagtttcagt 1260 tggacaaatt ccaaatacaa attcttgaga cattgataat attggtgagt gtcaaatttt 1320 catcaggtgt aaacacagct ggattgagaa taaattcaaa gaaaaaataa ttgaataacc 1380 atgttatgta taggcatttt agacagggaa agatcattag aagttca 1427 <210> 1636 <211> 1377 <212> DNA <213> Escherichia coli O157:H7 <400> 1636 cactcacatg atgcctcagc aaagaaagtc ctggtcacag aggaaaaagc ctcaataaat 60 cgccaggcag caactaatgg tttaccctgg ctggcagaca acgatcccat tattcttccc 120 ccgaatattg cccgccatgc cctcagccac cgcctttggc cgggagagcc agtaaaaaaa 180 ccaaccaaac ccgagaaaca aaatttaatt tcccgattgg caaatcgtac ttatcattat 240 tataaaaatc tgactttcga ttacagctca tgctctgatg aatgggctga tgcgattagc 300 caggcaatca gcttaattaa ggcccaaaag actgagatac ccgcgcgtac tatggcggta 360 cttacttttc tggaaatatg tttttgtcag ggctggaatg atgaaacctc atccgagttg 420 ctggatgaaa ttgtaagcac cttcggtatc gaatacgcaa ctgaaactgt catcttctgg 480 tggcaaattg atttcgattt tgactataaa gatgaacatt tgactttctt tattaattat 540 gcagatagca gcaaggacag ttatagaagg aataacgaca aatttagttt acgtctgcgt 600 aaacatttat cactagcaga agaagaagta tggcaaaatt gcattgcaaa attactcgtt 660 gcgttaccag atatatcact ctatcgccaa ccgttaattg ccattttaat gccagaaata 720 cccgaagtgg cccatgagat cgtacatcgt ttacaccagg tcgcagatgt tccacaactt 780 gaaatgttga aactggtagc gacagatcca ttcacgctcg aaatactgga gaactatcaa 840 tacattgatg tatttaacac ctatggtgcc agttggtcag ctacggtatt acgggagcaa 900 ggtatagcgg cactggctcg cctgactccc tatgctgaag aagataattg cggtgacgta 960 ctgaaatgta ttaatcatcc gttggccatt acgaataaaa agtgccgaaa attttccttc 1020 tgcaacgata gtggcattag ccgaagcatt ggtaaaaaaa gatgataaac gcaaacatac 1080 attgctggtt tcattactta atgcaaatcc tttatttgtc gaaaaattag tcatcggatt 1140 atcgtcgcaa gcggcaaatt tattgcaaca atgtcagcaa ttgctgaata gtcgcaatga 1200 agattttgca aactcagaaa ttctaccaat ggtactagtc tcgccgccct gggaaactca 1260 aaataaaaat aacgacaaca gtcctgtggg taaatacccg gcgaaaatcc cccctttacc 1320 gttgttttat caacctccat tatggactcg cccgaaactc aaaaatagca gcaaggt 1377 <210> 1637 <211> 1376 <212> DNA <213> Escherichia coli O157:H7 <400> 1637 tcctacctct aagtggctga tagtgcgtaa attattgcca taggttagcc aaacgttatg 60 gctatatacc aaagcttagt tccgcataac tttgattaaa ccttacgata acactacaca 120 ccatcagcat ctgggttact cggattactc ggaaatccac atactgataa tttaatcagt 180 acctctttcc gaataatcgt agtccaacct ggtccttttt tctctgactc gtctgcatta 240 ctcagaaaca aacgttatgt cgtctttttt ggcatggacg aattcatact gcagagttcg 300 atccagacct tgcgacagcg tatacggtgc cacaaaacct gaagaatgca ctttcgttgc 360 gtcaaactgt gttgttgcgc agaatttttt cacgcgcaca gagctgacag cgtatttttt 420 gcccgtaatt ttgctcagga tatcaaagca atatccaccc agcattccta gtgggtaagg 480 caagtgcata gaagggatct ttttgttcag gctttgttca acttcagcaa ccaactggtt 540 catgttcagg tctggcttat caacgtagtt ataaacctcg taacctgcgg caacattctt 600 cagtttgtac ttgataaact caacaatgtt tccaacataa gccatggact tatagttagt 660 ccctgcgccc accatcataa acttgccgcc agcgatctgt ttcagcaagt tatagacgtt 720 accgcggttg cgttcaccga agataacggt aggacggatg atagttaatg aacgttctgt 780 tggtgctttg ttataccatt cacgcagcac ttcctccgcc tgccacttgc ttttgccgta 840 gtggttgaaa gggtcgtgtg gatggttttc gtcagggttg tgtttgttca aaccataaac 900 agcaacggaa ctggtaaaga tgatattttt aacgccattt ttttccatgg ccgccagcac 960 attgcgggta ccctgaacgt tgacatcata atagagagaa gtagggctga cgtcatcgcg 1020 gtgttccgct gccagtagta caacagtgtc aaaaccggct aacgcctggt cgagtgcctg 1080 ttgatcacga acatcaccaa tctgtgtgat ttctggataa aagtggctct gctgtttgtc 1140 caggttcttg atattaaagt cagcaattgc cgtttcaagt agtcgggttc ctacgaatcc 1200 ggaagctcct atgagcaaaa cgttatcgtt cataaatcac tttagtctgg ttgttacgta 1260 agaaacacaa gataaagatg agtaccttcc ctgagtagtc aatgctgccc agccccagct 1320 ttaacagtta gtgtgaggat tataatcttt tagaacatta tatccagtaa gtttat 1376 <210> 1638 <211> 332 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(238..1233) <400> 1638 Met Asn Asp Asn Val Leu Leu Ile Gly Ala Ser Gly Phe Val Gly Thr 1 5 10 15 Arg Leu Leu Glu Thr Ala Ile Ala Asp Phe Asn Ile Lys Asn Leu Asp 20 25 30 Lys Gln Gln Ser His Phe Tyr Pro Glu Ile Thr Gln Ile Gly Asp Val 35 40 45 Arg Asp Gln Gln Ala Leu Asp Gln Ala Leu Ala Gly Phe Asp Thr Val 50 55 60 Val Leu Leu Ala Ala Glu His Arg Asp Asp Val Ser Pro Thr Ser Leu 65 70 75 80 Tyr Tyr Asp Val Asn Val Gln Gly Thr Arg Asn Val Leu Ala Ala Met 85 90 95 Glu Lys Asn Gly Val Lys Asn Ile Ile Phe Thr Ser Ser Val Ala Val 100 105 110 Tyr Gly Leu Asn Lys His Asn Pro Asp Glu Asn His Pro His Asp Pro 115 120 125 Phe Asn His Tyr Gly Lys Ser Lys Trp Gln Ala Glu Glu Val Leu Arg 130 135 140 Glu Trp Tyr Asn Lys Ala Pro Thr Glu Arg Ser Leu Thr Ile Ile Arg 145 150 155 160 Pro Thr Val Ile Phe Gly Glu Arg Asn Arg Gly Asn Val Tyr Asn Leu 165 170 175 Leu Lys Gln Ile Ala Gly Gly Lys Phe Met Met Val Gly Ala Gly Thr 180 185 190 Asn Tyr Lys Ser Met Ala Tyr Val Gly Asn Ile Val Glu Phe Ile Lys 195 200 205 Tyr Lys Leu Lys Asn Val Ala Ala Gly Tyr Glu Val Tyr Asn Tyr Val 210 215 220 Asp Lys Pro Asp Leu Asn Met Asn Gln Leu Val Ala Glu Val Glu Gln 225 230 235 240 Ser Leu Asn Lys Lys Ile Pro Ser Met His Leu Pro Tyr Pro Leu Gly 245 250 255 Met Leu Gly Gly Tyr Cys Phe Asp Ile Leu Ser Lys Ile Thr Gly Lys 260 265 270 Lys Tyr Ala Val Ser Ser Val Arg Val Lys Lys Phe Cys Ala Thr Thr 275 280 285 Gln Phe Asp Ala Thr Lys Val His Ser Ser Gly Phe Val Ala Pro Tyr 290 295 300 Thr Leu Ser Gln Gly Leu Asp Arg Thr Leu Gln Tyr Glu Phe Val His 305 310 315 320 Ala Lys Lys Asp Asp Ile Thr Phe Val Ser Glu * 325 330 <210> 1639 <211> 1368 <212> DNA <213> Escherichia coli O157:H7 <400> 1639 cggataatgc gcgaagtaca cggcttgctg gtcattaatt ttcttctctt gcgcaaaccc 60 ttctttaaca attgtccgta aatcagctcg aaccgtatta tcagagacgc ccaggctcgc 120 gctaatttca gcaactgtgt actctttccc cggattggcg agcatcacat tcaggagcgt 180 tacctggcgc ggattcaggc gtttaagcac accagagcta aacagcacac tatcgagttt 240 tgcgcttcgt tgtgtaattt catcgatatg ctgctgccag ttttgcagag cacgtttaat 300 gacacccgcc tgatattcaa ggaaataagt cagatccata ccatctgatt cagtgtactg 360 gtagctggcg gcatatttga ccggtgcagc atgaagcaaa cggctgatgg aaatatattt 420 aaagacatcg tagcccgatt tcagcatata ccagtaaaac agcgcccgac tggtgcgccc 480 gttgccatcc cgaaacggat gttcatgggc cagcataaaa tgcagaatgc aggcacggac 540 caacggatga atataccctt catggctgtt taaccactgg caaacttttt ccagccgttc 600 cggtaacaat gccgcagcgg gcggttgatg cactatattg ccatcatagt cggcgatcac 660 aacatcatct gtttcacgaa attctcccgg acgatatttc gcgtcattga ttccacccat 720 accaatggca tgtaactggc gaataagcgc aggtgtcagc ggttctgcga gtaagtgcgg 780 aatttccgcc atcagccggg catttcccgc aatcatatgc tcgtcttcag tgcgtggcga 840 ccgtcctgtt tccagcattt ttctcgccac cagcgttgta gtattcgcac cttccagctg 900 ggagctggtg atcggctctt ccaggcgtaa ctggcttaac tcggctccgg ccccgcgtaa 960 ccgttcagtc tgatctttca gcgccagcgc ggtagcacgt ttgtcgacaa gctcgcacgc 1020 ttctgcaatc accggggtaa tgttgaatcc ggcctgttca cccgcttcat tgcaataatt 1080 aattcgttgg atcgccgcgt tgcgcgccag acgggtaagc gtccacgcca catcgacgtt 1140 ttctcctttt ttgatgcggt actgcaactc atcaaaaggc agataacgtc ctttttcatc 1200 ggtaacccgg ttaaagcgca ggtgggcctg gagttcctca cccgataagt gtgataaagg 1260 aatcagcgtg ggaggtgatt tgatagccat ttgcttatct caaaaaagcg caatattgag 1320 atagtgtata gcaggaaaga gaaactatct caaaaaaagc aagttttg 1368 <210> 1640 <211> 1313 <212> DNA <213> Escherichia coli O157:H7 <400> 1640 tgaaccgccc cgggtttcct ggagagtatt ttatctgtga actcaggctg ccagatcatt 60 atttccgatg gaagcataat aagctttttc tgcttctgcc ggaggaatat ggcccagcct 120 ttccagcaat cgtcgattgt tataccagtc cacccacgtt agtgtggcca gttccacttc 180 tgtccggttt ttccagctct tacggtgtat tacctccgct ttgtaaagac cattgatgct 240 ctcagccatc gcgttgtcat acgagtcgcc agtactccct gttgatgcca gtaatccggc 300 ttccttaagc cgctgcgtgt aggccagcga tacatactga gaacctttat cactgtgatg 360 gattgtgccg gacggccgac gggcccacaa cgcctgctcc agtgcatcca gcacgaatgt 420 tgtttccatg gatgatgaga cctgccatcc cacgatgtat ccggcgaaca catcaatgat 480 gaacgccaca taaacgaagc cctgccatgt gcttacccag gtaaaatcag ccacccacaa 540 ctggtctgga cgttctgcca cgaactgacg gtttacgcgg tcgcatgcgg caacggcttt 600 ccggctgacg gtagtgcgga cctttttacc ccggagaaca ccggcaagtc ccataactgc 660 catgagacgt gccacagtgc atctggccac tctgatacct tcccgtaaca actgacgcca 720 gactttacgc acaccgtata cctggtgatt ttcatcgtat acgcgctgta tctctttctt 780 cagccagtca tcgtgctgcg cacgggcact gcgtttatcc ggatgatgtc gctgttgctg 840 acaatggtaa tacgttgacg gggcaatatg cagttcgctg cataccggtc cgaccccgta 900 ctgctcacgc agcttatcca gcagtggcat cattttttcc agaggcggtc gaactccgcc 960 ttcgcaaaat aagcggaagc ctggcgaagg atatcgttac tgcggcgcag ttcacgattt 1020 tcacgttcca gctctttcag acgctgacgt tcagcggtgg tgagtccacc atcaccactc 1080 ccggtatccc gctcatgctg acgaacccac acacgcagag tctctggtgt acagccaatc 1140 tttggggcaa tggaacaaat tgccgcccat tgtgagtcat attcgccctg actttccaga 1200 accatacgaa ctgcccgttg acggacctcg ggggaaaaac gagtattttt agtcatcctg 1260 tttacctctt tctcagggag tttagtctcc aggatttccg gggcggttca atc 1313 <210> 1641 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43..933) <400> 1641 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Lys Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Val Ser Arg Lys 100 105 110 Ala Val Ala Ala Cys Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Trp Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Gln Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Gln Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Thr Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Glu Arg 260 265 270 Leu Gly His Ile Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asn Asp Leu Ala Ala * 290 295 <210> 1642 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(930..1256) <400> 1642 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Val 1 5 10 15 Arg Met Val Leu Glu Ser Gln Gly Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Ser Gly Asp Gly Gly 50 55 60 Leu Thr Thr Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1643 <211> 1313 <212> DNA <213> Escherichia coli O157:H7 <400> 1643 tgaaccgccc cggttttcct ggagagtgtt ttatctgtga actcaggctg ccagatcatc 60 gtttccgatg gaagcataat aagctttttc tgcttctgcc ggaggagtat ggcccagcct 120 tcccagcaat cgtcgattgt tataccagtc cacccacgtt agtgtggcca gttccacttc 180 tgcacggttt ttccagctct tacggtgtat tacctccgct ttgtaaagac cattgatgct 240 ctcagccatc gcgttgtcat acgagtcgcc tgtactccct gttgatgcca gtaatccggc 300 ttcttttagt cgctccgtat aggccagtga cacatactga gagcctttat cgctgtgatg 360 gatggtgcca gacggacgac gggcccacaa cgcctgctcc agcgcatcca gcacgaatgt 420 cgtttccata gacgatgaga cccgccaccc cacgatgtat ccggcaaaca catcaatgat 480 aaacgccaca tagacgaagc cctgccatgt gctgacgtaa gtaaaatcag ccacccacag 540 ctggtcaggt cgttctgcca cgaactgacg gtttacgcgg tcgcctgcgg caacggcttt 600 ccggctgatg gtcgtacgga cctttttacc ccggagaaca ccggcaagtc ccataaccgc 660 catgagacgt gccactgtac atctggccac cctgattcct tcccgtaaca actgacgcca 720 gactttacgc acaccgtaca cctgatgatt ttcatcgtat acgcgctgta tctctctctt 780 cagccagtcg tcgtgctgcg cacgggcact gcgtttatcc ggatgatgtc gctgttgctg 840 acaatggtaa tacgttgacg gggcaatatg cagttcgctg cataccggtc cgaccccgta 900 ctgctcacgc agcttatcca gcagtggcat cattttttcc agaggcggtc gaactccgcc 960 ttcgcaaaat aagcggaagc ctggcgaagg atatcgttac tgcggcgcag ttcacgattt 1020 tcacgttcca gctctttcag acgctgacgt tcagcgctgg tgagcccacc atcaccgccc 1080 ccggtatccc gctcatgctg gcgaacccag acacgcagag tctccggcgt acagccaatc 1140 tttggggcaa tggaacaaat tgccgcccac tgtgagtcat attcatcctg actttccaga 1200 accatacgaa tcgcccgctg acggacttcg ggggaaaaac gagtattttt agtcatcctg 1260 tttacctctt tctcagggag tttagtctcc aggatttccg gggcggttca ttt 1313 <210> 1644 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43..933) <400> 1644 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 1645 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(930..1256) <400> 1645 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1646 <211> 1313 <212> DNA <213> Escherichia coli O157:H7 <400> 1646 gaaccgcccc gggaatcctg gagactaaac tccctgagaa agaggtaaac aggatgacta 60 aaaatacacg tttttccccc gaggtccgtc aacgggcagt ccgtatggtt ctggaaagtc 120 agggcgaata tgactcacaa tgggcggcaa tttgttccat tgccccaaag attggctgta 180 caccagagac tctgcgtgtg tgggttcgtc agcatgagcg ggataccggg ggcggtgatg 240 gtggactcac caccgctgaa cgtcagcgtc tgaaagagct ggaacgtgaa aatcgtgaac 300 tgcgccgcag taacgatatc cttcgccagg cttccgctta ttttgcgaag gcggagttcg 360 accgcctctg gaaaaaataa tgccgctgct ggataagctg cgtgagcagt acggggtcgg 420 accggtatgc agtgaactgc atattgcccc gtcaacggat taccactgtc agcaacagcg 480 acatcatccg gataaacgca gtgcccgtgc gcagcgcgat gactggctga agagagagat 540 acagcgcgta tacgatgaaa atcatcaggt gtacggtgtg cgtaaagtct ggcgccagtt 600 gttacgcgaa ggtatcaggg tggccagatg tacagtggcg cgcctcatgg cggttatggg 660 acttgccggt gttctccggg gtaaaaaggt ccgtactacc gtcagccgga aagccgtttc 720 cgcaggcgac cgcgtaaacc gtcagttcgt ggcagaacgt cctgaccagc tgtgggtggc 780 tgattttact tacgtcagca catggcaggg cttcgtctat gtggcgttca tcattgatgt 840 gttttccgga tgtatcgtgg ggtggcgagt ctcatcgtct atggaaacga cattcgtgct 900 ggatgcactg gagcaggcgt tgtgggcccg tcggccgtcc ggcacagtcc atcacagtga 960 taaaggttct cagtatgtat cactggccta tacggagcga ctaaaagaag caaaactgct 1020 ggcatcaaca gggagtacag gtgactcgta tgacaacgcg atggcggaga gcatcaatgg 1080 tctttacaaa gcggaggtaa tacaccgtaa gagctggaaa aaccgtgcag aagtggaact 1140 ggccacactc acgtgggtgg actggtataa caatcgacga ttgctgggaa ggctgggtca 1200 tatccctccg gcagaagcag aaaaagctta ttatgcttcc atcagaaacg atgatctggc 1260 agcctgagtt cacagataaa acactctcca ggaaaaccgg ggcggttcac tgt 1313 <210> 1647 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(54..380) <400> 1647 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Val 1 5 10 15 Arg Met Val Leu Glu Ser Gln Gly Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Thr Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1648 <211> 296 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(380..1267) <400> 1648 Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro Val 1 5 10 15 Cys Ser Glu Leu His Ile Ala Pro Ser Thr Asp Tyr His Cys Gln Gln 20 25 30 Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln Arg Asp Asp 35 40 45 Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln Val 50 55 60 Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile Arg 65 70 75 80 Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu Ala 85 90 95 Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Val Ser Arg Lys Ala 100 105 110 Val Ser Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg Pro 115 120 125 Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln Gly 130 135 140 Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ser Gly Cys Ile Val 145 150 155 160 Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp Ala 165 170 175 Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Val His His 180 185 190 Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg Leu 195 200 205 Lys Glu Ala Lys Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser Tyr 210 215 220 Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu Val 225 230 235 240 Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala Thr 245 250 255 Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg Leu 260 265 270 Gly His Ile Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser Ile 275 280 285 Arg Asn Asp Asp Leu Ala Ala * 290 295 <210> 1649 <211> 1313 <212> DNA <213> Escherichia coli O157:H7 <400> 1649 tgaaccgccc cgggtttcct ggagagtgtt ttatctgtga actcaggctg ccagatcatc 60 gtttccgatg gaagcataat aagctttttc tgcttctgcc ggaggagtat ggcccagcct 120 tcccagcaat cgtcgattgt tataccagtc cacccacgtt agtgtggcca gttccacttc 180 tgcacggttt ttccagctct tacggtgtat tacctccgct ttgtaaagac cattgatgct 240 ctcagccatc gcgttgtcat acgagtcgcc tgtactccct gttgatgcca gtaatccggc 300 ttcttttagt cgctccgtat aggccagtga cacatactga gagcctttat cgctgtgatg 360 gatggtgcca gacggacgac gggcccacaa cgcctgctcc agcgcatcca gcacgaatgt 420 cgtttccata gacgatgaga cccgccaccc cacgatgtat ccggcaaaca catcaatgat 480 aaacgccaca tagacgaagc cctgccatgt gctgacgtaa gtaaaatcag ccacccacag 540 ctggtcaggt cgttctgcca cgaactgacg gtttacgcgg tcgcctgcgg caacggcttt 600 ccggctgatg gtcgtacgga cctttttacc ccggagaaca ccggcaagtc ccataaccgc 660 catgagacgt gccactgtac atctggccac cctgattcct tcccgtaaca actgacgcca 720 gactttacgc acaccgtaca cctgatgatt ttcatcgtat acgcgctgta tctctctctt 780 cagccagtcg tcgtgctgcg cacgggcact gcgtttatcc ggatgatgtc gctgttgctg 840 acaatggtaa tacgttgacg gggcaatatg cagttcgctg cataccggtc cgaccccgta 900 ctgctcacgc agcttatcca gcagtggcat cattttttcc agaggcggtc gaactccgcc 960 ttcgcaaaat aagcggaagc ctggcgaagg atatcgttac tgcggcgcag ttcacgattt 1020 tcacgttcca gctctttcag acgctgacgt tcagcgctgg tgagcccacc atcaccgccc 1080 ccggtatccc gctcatgctg gcgaacccag acacgcagag tctccgacgt acagccaatc 1140 tttggggcaa tggaacaaat tgccgcccac tgtgagtcat attcatcctg actttccaga 1200 accatacgaa tcgcccgctg acggacttcg ggggaaaaac gagtattttt agtcatcctg 1260 tttacctctt tctcagggag tttagtctcc aggatttccg gggcggttca gat 1313 <210> 1650 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(43..933) <400> 1650 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 1651 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(930..1256) <400> 1651 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Ser Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1652 <211> 1313 <212> DNA <213> Escherichia coli O157:H7 <400> 1652 aaccgccccg gaaatcctgg agactaaact ccctgagaaa gaggtaaaca ggatgactaa 60 aaatactcgt ttttcccccg aagtccgtca gcgggcgatt cgtatggttc tggaaagtca 120 ggatgaatat gactcacagt gggcggcaat ttgttccatt gccccaaaga ttggctgtac 180 gccggagact ctgcgtgtct gggttcgcca gcatgagcgg gataccgggg gcggtgatgg 240 tgggctcacc agcgctgaac gtcagcgtct gaaagagctg gaacgtgaaa atcgtgaact 300 gcgccgcagt aacgatatcc ttcgccaggc ttccgcttat tttgcgaagg cggagttcga 360 ccgcctctgg aaaaaatgat gccactgctg gataagctgc gtgagcagta cggggtcgga 420 ccggtatgca gcgaactgca tattgccccg tcaacgtatt accattgtca gcaacagcga 480 catcatccgg ataaacgcag tgcccgtgcg cagcacgacg actggctgaa gagagagata 540 cagcgcgtat acgatgaaaa tcatcaggtg tacggtgtgc gtaaagtctg gcgtcagttg 600 ttacgggaag gaatcagggt ggccagatgt acagtggcac gtctcatggc ggttatggga 660 cttgccggtg ttctccgggg taaaaaggtc cgtacgacca tcagccggaa agccgttgcc 720 gcaggcgacc gcgtaaaccg tcagttcgtg gcagaacgac ctgaccagct gtgggtggct 780 gattttactt acgtcagcac atggcagggc ttcgtctatg tggcgtttat cattgatgtg 840 tttgccggat acatcgtggg gtggcgggtc tcatcgtcta tggaaacgac attcgtgctg 900 gatgcgctgg agcaggcgtt gtgggcccgt cgtccgtctg gcaccatcca tcacagcgat 960 aaaggctctc agtatgtgtc actggcctat acggagcgac taaaagaagc cggattactg 1020 gcatcaacag ggagtacagg cgactcgtat gacaacgcga tggctgagag catcaatggt 1080 ctttacaaag cggaggtaat acaccgtaag agctggaaaa accgtgcaga agtggaactg 1140 gccacactaa cgtgggtgga ctggtataac aatcgacgat tgctgggaag gctgggccat 1200 actcctccgg cagaagcaga aaaagcttat tatgcttcca tcggaaacga tgatctggca 1260 gcctgagttc acagataaaa cactctccag gaaacccggg gcggttcagg atg 1313 <210> 1653 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(53..379) <400> 1653 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1654 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(376..1266) <400> 1654 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 1655 <211> 1307 <212> DNA <213> Escherichia coli O157:H7 <400> 1655 tgaaccgccc cggaaatcct ggagactaaa ctccctgaga aagaggtaaa caggatgact 60 aaaaatactc gtttttcccc cgaagtccgt cagcgggcga ttcgtatggt tctggaaagt 120 caggatgaat atgactcaca gtgggcggca atttgttcca ttgccccaaa gattggctgt 180 acgccggaga ctctgcgtgt ctgggttcgc cagcatgagc gggataccgg gggcggtgat 240 ggtgggctca ccagcgctga acgtcagcgt ctgaaagagc tggaacgtga aaatcgtgaa 300 ctgcgccgca gtaacgatat ccttcgccag gcttccgctt attttgcgaa ggcggagttc 360 gaccgcctct ggaaaaaatg atgccactgc tggataagct gcgtgagcag tacggggtcg 420 gaccggtatg cagcgaactg catattgccc cgtcaacgta ttaccattgt cagcaacagc 480 gacatcatcc ggataaacgc agtgcccgtg cgcagcacga cgactggctg aagagagaga 540 tacagcgcgt atacgatgaa aatcatcagg tgtacggtgt gcgtaaagtc tggcgtcagt 600 tgttacggga aggaatcagg gtggccagat gtacagtggc acgtctcatg gcggttatgg 660 gacttgccgg tgttctccgg ggtaaaaagg tccgtacgac catcagccgg aaagccgttg 720 ccgcaggcga ccgcgtaaac cgtcagttcg tggcagaacg acctgaccag ctgtgggtgg 780 ctgattttac ttacgtcagc acatggcagg gcttcgtcta tgtggcgttt atcattgatg 840 tgtttgccgg atacatcgtg gggtggcggg tctcatcgtc tatggaaacg acattcgtgc 900 tggatgcgct ggagcaggcg ttgtgggccc gtcgtccgtc tggcaccatc catcacagcg 960 ataaaggctc tcagtatgtg tcactggcct atacggagcg actaaaagaa gccggattac 1020 tggcatcaac agggagtaca ggcgactcgt atgacaacgc gatggctgag agcatcaatg 1080 gtctttacaa agcggaggta atacaccgta agagctggaa aaaccgtgca gaagtggaac 1140 tggccacact aacgtgggtg gactggtata acaatcgacg attgctggga aggctgggcc 1200 atactcctcc ggcagaagca gaaaaagctt attatgcttc catcggaaac gatgatctgg 1260 cagcctgagt tcacagataa aacactctcc aggaaaaccg gggcggt 1307 <210> 1656 <211> 109 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(55..381) <400> 1656 Met Thr Lys Asn Thr Arg Phe Ser Pro Glu Val Arg Gln Arg Ala Ile 1 5 10 15 Arg Met Val Leu Glu Ser Gln Asp Glu Tyr Asp Ser Gln Trp Ala Ala 20 25 30 Ile Cys Ser Ile Ala Pro Lys Ile Gly Cys Thr Pro Glu Thr Leu Arg 35 40 45 Val Trp Val Arg Gln His Glu Arg Asp Thr Gly Gly Gly Asp Gly Gly 50 55 60 Leu Thr Ser Ala Glu Arg Gln Arg Leu Lys Glu Leu Glu Arg Glu Asn 65 70 75 80 Arg Glu Leu Arg Arg Ser Asn Asp Ile Leu Arg Gln Ala Ser Ala Tyr 85 90 95 Phe Ala Lys Ala Glu Phe Asp Arg Leu Trp Lys Lys * 100 105 <210> 1657 <211> 297 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(378..1268) <400> 1657 Met Met Pro Leu Leu Asp Lys Leu Arg Glu Gln Tyr Gly Val Gly Pro 1 5 10 15 Val Cys Ser Glu Leu His Ile Ala Pro Ser Thr Tyr Tyr His Cys Gln 20 25 30 Gln Gln Arg His His Pro Asp Lys Arg Ser Ala Arg Ala Gln His Asp 35 40 45 Asp Trp Leu Lys Arg Glu Ile Gln Arg Val Tyr Asp Glu Asn His Gln 50 55 60 Val Tyr Gly Val Arg Lys Val Trp Arg Gln Leu Leu Arg Glu Gly Ile 65 70 75 80 Arg Val Ala Arg Cys Thr Val Ala Arg Leu Met Ala Val Met Gly Leu 85 90 95 Ala Gly Val Leu Arg Gly Lys Lys Val Arg Thr Thr Ile Ser Arg Lys 100 105 110 Ala Val Ala Ala Gly Asp Arg Val Asn Arg Gln Phe Val Ala Glu Arg 115 120 125 Pro Asp Gln Leu Trp Val Ala Asp Phe Thr Tyr Val Ser Thr Trp Gln 130 135 140 Gly Phe Val Tyr Val Ala Phe Ile Ile Asp Val Phe Ala Gly Tyr Ile 145 150 155 160 Val Gly Trp Arg Val Ser Ser Ser Met Glu Thr Thr Phe Val Leu Asp 165 170 175 Ala Leu Glu Gln Ala Leu Trp Ala Arg Arg Pro Ser Gly Thr Ile His 180 185 190 His Ser Asp Lys Gly Ser Gln Tyr Val Ser Leu Ala Tyr Thr Glu Arg 195 200 205 Leu Lys Glu Ala Gly Leu Leu Ala Ser Thr Gly Ser Thr Gly Asp Ser 210 215 220 Tyr Asp Asn Ala Met Ala Glu Ser Ile Asn Gly Leu Tyr Lys Ala Glu 225 230 235 240 Val Ile His Arg Lys Ser Trp Lys Asn Arg Ala Glu Val Glu Leu Ala 245 250 255 Thr Leu Thr Trp Val Asp Trp Tyr Asn Asn Arg Arg Leu Leu Gly Arg 260 265 270 Leu Gly His Thr Pro Pro Ala Glu Ala Glu Lys Ala Tyr Tyr Ala Ser 275 280 285 Ile Gly Asn Asp Asp Leu Ala Ala * 290 295 <210> 1658 <211> 1041 <212> DNA <213> Escherichia coli O157:H7 <400> 1658 tcccgagaat gcactgaaaa gaggcgatta acggccagct aatcgccaga actccttacc 60 atgaagagca aaaatggcag caaattctgc gtccaatttt gctgcccgat gagagctaca 120 tttttcaatt ttaacaaaag attgccgcga cactggtcta acggcaaaga agattttcat 180 tgcaccacac tctgcttcag ccgctcattg gcggtcttaa tccattcccg gtggtgtttt 240 ctataatgag gtcttgagcg tttagccgta tcaaccacgg caacatactg ctcgttggct 300 tcacgtaacc gactcatttt cgccaacatt tccgcatagt aaatacgcgc ctgcgggccg 360 gggtaataag aaatcaatac ttcaaactcg ctttccgcat cagcgtattt ttcttgtgcg 420 gctaacgttc tggcaaataa caaatgcccg tctgccgact gaaaatcagg gttataacgc 480 atcacatctt ccagcgtctg ctgacaggcg gcgaactcct gaatagcaaa ctgtgcctgc 540 gccaggctta gcatcattgc cgcttcatgg gcgaatatcc cgcttaacgc ctgctgataa 600 tggggaacag cttcgtgata acgccccaga cgcgccagtt cattagccaa cgcataatgg 660 ttttgattcg tctcggcaat cgccagttct tcggttaatt tgcgcaggtg gcgctcaggg 720 ttgagtttgt cctgcaggcg catcagcaaa gtatgcccgt gacggtcagc gcccgtttca 780 ggcagcatca ctatgacgaa atacgccacg cagccaatca ccggaaaaca gaaaatgata 840 aaaatccagt accgctcttg tccggtacgg taagcgtgaa tacagcaaag cagttcaagc 900 atgacaacaa cggcataatg catgggaggg aacctttccg tggcaaataa gtggtctggt 960 tttaatcctc ccggtcagtt gaaacaagtc tgtatacgga cgaataaccc ggcagaactt 1020 agctgccggg ttatcgataa t 1041 <210> 1659 <211> 249 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(177..923) <400> 1659 Met His Tyr Ala Val Val Val Met Leu Glu Leu Leu Cys Cys Ile His 1 5 10 15 Ala Tyr Arg Thr Gly Gln Glu Arg Tyr Trp Ile Phe Ile Ile Phe Cys 20 25 30 Phe Pro Val Ile Gly Cys Val Ala Tyr Phe Val Ile Val Met Leu Pro 35 40 45 Glu Thr Gly Ala Asp Arg His Gly His Thr Leu Leu Met Arg Leu Gln 50 55 60 Asp Lys Leu Asn Pro Glu Arg His Leu Arg Lys Leu Thr Glu Glu Leu 65 70 75 80 Ala Ile Ala Glu Thr Asn Gln Asn His Tyr Ala Leu Ala Asn Glu Leu 85 90 95 Ala Arg Leu Gly Arg Tyr His Glu Ala Val Pro His Tyr Gln Gln Ala 100 105 110 Leu Ser Gly Ile Phe Ala His Glu Ala Ala Met Met Leu Ser Leu Ala 115 120 125 Gln Ala Gln Phe Ala Ile Gln Glu Phe Ala Ala Cys Gln Gln Thr Leu 130 135 140 Glu Asp Val Met Arg Tyr Asn Pro Asp Phe Gln Ser Ala Asp Gly His 145 150 155 160 Leu Leu Phe Ala Arg Thr Leu Ala Ala Gln Glu Lys Tyr Ala Asp Ala 165 170 175 Glu Ser Glu Phe Glu Val Leu Ile Ser Tyr Tyr Pro Gly Pro Gln Ala 180 185 190 Arg Ile Tyr Tyr Ala Glu Met Leu Ala Lys Met Ser Arg Leu Arg Glu 195 200 205 Ala Asn Glu Gln Tyr Val Ala Val Val Asp Thr Ala Lys Arg Ser Arg 210 215 220 Pro His Tyr Arg Lys His His Arg Glu Trp Ile Lys Thr Ala Asn Glu 225 230 235 240 Arg Leu Lys Gln Ser Val Val Gln * 245 <210> 1660 <211> 1011 <212> DNA <213> Escherichia coli O157:H7 <400> 1660 gccacaccgc atccggcatc agcaccttac ttatcacatt tcttcacatc aatattccag 60 tcagcaccag acgcaacctg atgtttctgc gcgaaattat ccatattcag cgccacggaa 120 acattcaata agctgttcag atacaccatc ggctgtcctt ccggcacatc gccgaagctt 180 gcgacatacg gcattttccc tgcgtatttt tgccgggaac cttcggaaat ggtcacacac 240 aacgtgtcgt tgagtttgat ccccgcctga ttcagcaact cgtcgctgat attgctccag 300 acgttgccgt actgaatatc gagaatcggg atattgccct tcacttcacc ttttgttgct 360 tttgctttct gataagaaag ttcgacaacc tttgcaggaa gctcaggccc cacctgctcg 420 aacgtgatcg ccccggaagc cagacgtgca ccggtgtagg catacacgtc acgaccgtgg 480 aaggtatatg acttttcaga acctttcagg cggttagctt tttcgtcgat ttcccggacg 540 ctctcaatac ccagcgattc cgccaccaaa gtgagcgtac cgttatccgg tgaaacgaag 600 tattgaccgt ttttggtttt cagcactatc gatttacggt cagtgcctac gcccggatcg 660 accacactga caaataccga accttgcggc cagtaactgg cggtctgata caggcggtaa 720 gcgccttccc agatgttata cggtggaatt tcgtgtgtta aatcaaatat tttaagatta 780 tggtcaacac cgaatgcgac ccctttcatc gccgagacgg caccatcttt caggctaaaa 840 tcagtttgta aaatcaaagc gttatccgca taagcggatg atgatcccag acacgttaat 900 aaaaataacg ttgcgagcgt ttttttcatt tttgtttccc ttcatttatc tgatgatttt 960 ccagctgtgt agccagcccc agtttgtctg gcctcctcga gtgtacaatg c 1011 <210> 1661 <211> 301 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(27..929) <400> 1661 Met Lys Lys Thr Leu Ala Thr Leu Phe Leu Leu Thr Cys Leu Gly Ser 1 5 10 15 Ser Ser Ala Tyr Ala Asp Asn Ala Leu Ile Leu Gln Thr Asp Phe Ser 20 25 30 Leu Lys Asp Gly Ala Val Ser Ala Met Lys Gly Val Ala Phe Gly Val 35 40 45 Asp His Asn Leu Lys Ile Phe Asp Leu Thr His Glu Ile Pro Pro Tyr 50 55 60 Asn Ile Trp Glu Gly Ala Tyr Arg Leu Tyr Gln Thr Ala Ser Tyr Trp 65 70 75 80 Pro Gln Gly Ser Val Phe Val Ser Val Val Asp Pro Gly Val Gly Thr 85 90 95 Asp Arg Lys Ser Ile Val Leu Lys Thr Lys Asn Gly Gln Tyr Phe Val 100 105 110 Ser Pro Asp Asn Gly Thr Leu Thr Leu Val Ala Glu Ser Leu Gly Ile 115 120 125 Glu Ser Val Arg Glu Ile Asp Glu Lys Ala Asn Arg Leu Lys Gly Ser 130 135 140 Glu Lys Ser Tyr Thr Phe His Gly Arg Asp Val Tyr Ala Tyr Thr Gly 145 150 155 160 Ala Arg Leu Ala Ser Gly Ala Ile Thr Phe Glu Gln Val Gly Pro Glu 165 170 175 Leu Pro Ala Lys Val Val Glu Leu Ser Tyr Gln Lys Ala Lys Ala Thr 180 185 190 Lys Gly Glu Val Lys Gly Asn Ile Pro Ile Leu Asp Ile Gln Tyr Gly 195 200 205 Asn Val Trp Ser Asn Ile Ser Asp Glu Leu Leu Asn Gln Ala Gly Ile 210 215 220 Lys Leu Asn Asp Thr Leu Cys Val Thr Ile Ser Glu Gly Ser Arg Gln 225 230 235 240 Lys Tyr Ala Gly Lys Met Pro Tyr Val Ala Ser Phe Gly Asp Val Pro 245 250 255 Glu Gly Gln Pro Met Val Tyr Leu Asn Ser Leu Leu Asn Val Ser Val 260 265 270 Ala Leu Asn Met Asp Asn Phe Ala Gln Lys His Gln Val Ala Ser Gly 275 280 285 Ala Asp Trp Asn Ile Asp Val Lys Lys Cys Asp Lys * 290 295 300 <210> 1662 <211> 1010 <212> DNA <213> Escherichia coli O157:H7 <400> 1662 catagagaag gcgtattaaa aaagccaata ttcgttcagc tatcaagagc gtatttgcat 60 agctggagag cgttgatccg aaagaatccc ttcgctacag tcaaaatagg taacgtaacc 120 gtttattgcg tgaatgagcg atttttgaca gtattcttat tcaggacgct tattctgagt 180 tttttattca gagtggagct atcagcatga aagtaagaaa cccagaacag attagtatcc 240 ctgctagtaa taccactaaa gatccaggcc ttactaattc tcagattatc aggatggcta 300 acttggtcaa aaagaccgag aatatgaata tctttgaaga gctatgggag acgttacgca 360 atctcttcca gtcagataaa cattcccaga ctgcggcaag gcaaattctg aaggatgcat 420 tttatttcca gaatagtgat gactactcaa aatactttac cggggctgtc gacgggaagg 480 cgcgtgataa gttaactcac tggctgataa aatttaatga actcaaagaa tacgcaaaag 540 atccggaaaa tatggccgcg aaggcctcac tctcgccaga aggtacgtta tgcgtcagtt 600 tttttattgg cgatgaggcg atatttactc tggagttgca gctgaaaaag agcaccagga 660 ccggggggat tgatctgagt aatgcttact ttaacggggt tgtcatttgt ggtattgact 720 gtctcgaggt tgacctgagc aatgctgaaa cgaacaatag ccgttggtat gactgacctg 780 cgcgaggtta acctgaaaaa gctgaccttt ccggccagaa caaggctaga ctgcgccgtt 840 attgattaac tcagaatatg aaagaggggc tggaatgccc cttctttaat cttatttgcg 900 acgctaatca gacgatgcat aaaacagaga aaatataaaa gtaatgtatt ttatcattcc 960 gtctgaatat aaaaaatgcg ctcatgaccg ccaaaaggcg caagctactc 1010 <210> 1663 <211> 190 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(207..776) <400> 1663 Met Lys Val Arg Asn Pro Glu Gln Ile Ser Ile Pro Ala Ser Asn Thr 1 5 10 15 Thr Lys Asp Pro Gly Leu Thr Asn Ser Gln Ile Ile Arg Met Ala Asn 20 25 30 Leu Val Lys Lys Thr Glu Asn Met Asn Ile Phe Glu Glu Leu Trp Glu 35 40 45 Thr Leu Arg Asn Leu Phe Gln Ser Asp Lys His Ser Gln Thr Ala Ala 50 55 60 Arg Gln Ile Leu Lys Asp Ala Phe Tyr Phe Gln Asn Ser Asp Asp Tyr 65 70 75 80 Ser Lys Tyr Phe Thr Gly Ala Val Asp Gly Lys Ala Arg Asp Lys Leu 85 90 95 Thr His Trp Leu Ile Lys Phe Asn Glu Leu Lys Glu Tyr Ala Lys Asp 100 105 110 Pro Glu Asn Met Ala Ala Lys Ala Ser Leu Ser Pro Glu Gly Thr Leu 115 120 125 Cys Val Ser Phe Phe Ile Gly Asp Glu Ala Ile Phe Thr Leu Glu Leu 130 135 140 Gln Leu Lys Lys Ser Thr Arg Thr Gly Gly Ile Asp Leu Ser Asn Ala 145 150 155 160 Tyr Phe Asn Gly Val Val Ile Cys Gly Ile Asp Cys Leu Glu Val Asp 165 170 175 Leu Ser Asn Ala Glu Thr Asn Asn Ser Arg Trp Tyr Asp * 180 185 <210> 1664 <211> 996 <212> DNA <213> Escherichia coli O157:H7 <400> 1664 gaattagaat agtgttagta cccctgaatc aaggggtact aatgaatgtg gtaaatcatt 60 tgcaaacatt ttactttgca aaaacttccg gcccttttat tgccaatgta ttcaaaatac 120 gtagtgccgg gccgctcggt tttatttcat tacgttccca tttcgagaca ctttcttttg 180 acattcccat tgtatgtgcc agcacggatt gtgacatgcc gtatcgggtg cggatggctt 240 tgatctcttc acccgtcatt gatttgactt tggctatacg ggcgctgact tcacgggctt 300 tgaccatgac ggcaatggca tcaacctcac tatcagacat caggcccagt gcattcagtt 360 cctttgcatc ttccagcatc atttgtaatt tatcgctcat ttttcacctc aatcaagaag 420 ccagtttcga tcaaatcctc tatttgctta ttgctaaagg ccagaaatgc atttgccatt 480 tttttgtagg ctgccagttc atcatcttcg atttctttgc ttcctttact gcttagacca 540 ctcttggacc aaccatcata aaaaaacaca tgatttgctg atttaaaaaa gataattgtt 600 ctggctccac cactctttcc ttgttggagg ggtaaccgtt ttttgatgac accgctacct 660 aaatcagcct cccatatgcc ttgcatcact tcttcagcgg cagccatgag aactttatcg 720 tgaataccaa gttttttcgt gctttggctg aatcgccttg ccttatacac acccatacat 780 ccatccttgt ggtaatgttt actatagtaa ccattacgct tatttcaagt aattgcgatc 840 aaaactttaa tttggtgtga aaaagtgaga gttgcctcga gtacgattca tttttctcga 900 tttatgcgtc aggggatttt gtgcgtaagg gtaggacatc gggaagggta gtagaggcag 960 atcgaagaac aatatccttg ttagatctgc ctttag 996 <210> 1665 <211> 165 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(42..536) <400> 1665 Met Asn Val Val Asn His Leu Gln Thr Phe Tyr Phe Ala Lys Thr Ser 1 5 10 15 Gly Pro Phe Ile Ala Asn Val Phe Lys Ile Arg Ser Ala Gly Pro Leu 20 25 30 Gly Phe Ile Ser Leu Arg Ser His Phe Glu Thr Leu Ser Phe Asp Ile 35 40 45 Pro Ile Val Cys Ala Ser Thr Asp Cys Asp Met Pro Tyr Arg Val Arg 50 55 60 Met Ala Leu Ile Ser Ser Pro Val Ile Asp Leu Thr Leu Ala Ile Arg 65 70 75 80 Ala Leu Thr Ser Arg Ala Leu Thr Met Thr Ala Met Ala Ser Thr Ser 85 90 95 Leu Ser Asp Ile Arg Pro Ser Ala Phe Ser Ser Phe Ala Ser Ser Ser 100 105 110 Ile Ile Cys Asn Leu Ser Leu Ile Phe His Leu Asn Gln Glu Ala Ser 115 120 125 Phe Asp Gln Ile Leu Tyr Leu Leu Ile Ala Lys Gly Gln Lys Cys Ile 130 135 140 Cys His Phe Phe Val Gly Cys Gln Phe Ile Ile Phe Asp Phe Phe Ala 145 150 155 160 Ser Phe Thr Ala * <210> 1666 <211> 989 <212> DNA <213> Escherichia coli O157:H7 <400> 1666 ttaaagaatg tgtgcggata taaatttaaa cccgcataag tgattattta cttgcttcag 60 cctgacggat tgccgccact tttttaccaa ataccagttg cagtataact aacaaggtaa 120 acggaggtag aagtgcggca gcggcgggaa ttcccagcgc gccttttatc aacatggaac 180 cggaggcaat cagcaataaa aagaccatca cacggaacac tttgactgaa atacgtttat 240 gcacatattg tccaaccagt gaaccgagga tcatggtggg aatacaaaac agcaccagtt 300 taaagatcga aacagtcaaa attccgctgg tcgccagccc gccgatcacc gcgatgttgt 360 ttgcggtgaa gaaagcgttc agagtgccac gaaatgccgc cgggcctaag ttacgcagca 420 taccgtagat aaccatcggt ggtccgttgg ttgagaaagc tgcgcctaat gcgcctgcta 480 ctgcaccgat aggtgcggcg atccagctac ggtcataaat cggcaggcgt ggaataaaca 540 tactgtaaaa ggagtacagg ataaggaatc cgcctaagcc cactttcata aaatggtcgg 600 gtaaatacga cagtgcatat aaaccgacgg gtattcccag aaacgagaaa ataatcagta 660 ccattgccga tcgccaatcc gtttctttac gtgacagcca ggtggcgtac aaggcggtcg 720 cggtgccgac aattaccgag agtggtgttg ccatttttac ggggagcatt aacgtgacga 780 gcggcatagt ggttaaacca ccgccaaatc ccgcgcatat ccccacaaag gtataaagaa 840 acattaacgc gataacgata cataccacgt ttgtttccag catgacccca tccggtgaaa 900 ataacgtaaa aaagtccata atatttcctg ttgtgtaaat acaactctaa acaatgatct 960 cgttcttttc ttaataaaat taattgtgt 989 <210> 1667 <211> 292 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(44..919) <400> 1667 Met Asp Phe Phe Thr Leu Phe Ser Pro Asp Gly Val Met Leu Glu Thr 1 5 10 15 Asn Val Val Cys Ile Val Ile Ala Leu Met Phe Leu Tyr Thr Phe Val 20 25 30 Gly Ile Cys Ala Gly Phe Gly Gly Gly Leu Thr Thr Met Pro Leu Val 35 40 45 Thr Leu Met Leu Pro Val Lys Met Ala Thr Pro Leu Ser Val Ile Val 50 55 60 Gly Thr Ala Thr Ala Leu Tyr Ala Thr Trp Leu Ser Arg Lys Glu Thr 65 70 75 80 Asp Trp Arg Ser Ala Met Val Leu Ile Ile Phe Ser Phe Leu Gly Ile 85 90 95 Pro Val Gly Leu Tyr Ala Leu Ser Tyr Leu Pro Asp His Phe Met Lys 100 105 110 Val Gly Leu Gly Gly Phe Leu Ile Leu Tyr Ser Phe Tyr Ser Met Phe 115 120 125 Ile Pro Arg Leu Pro Ile Tyr Asp Arg Ser Trp Ile Ala Ala Pro Ile 130 135 140 Gly Ala Val Ala Gly Ala Leu Gly Ala Ala Phe Ser Thr Asn Gly Pro 145 150 155 160 Pro Met Val Ile Tyr Gly Met Leu Arg Asn Leu Gly Pro Ala Ala Phe 165 170 175 Arg Gly Thr Leu Asn Ala Phe Phe Thr Ala Asn Asn Ile Ala Val Ile 180 185 190 Gly Gly Leu Ala Thr Ser Gly Ile Leu Thr Val Ser Ile Phe Lys Leu 195 200 205 Val Leu Phe Cys Ile Pro Thr Met Ile Leu Gly Ser Leu Val Gly Gln 210 215 220 Tyr Val His Lys Arg Ile Ser Val Lys Val Phe Arg Val Met Val Phe 225 230 235 240 Leu Leu Leu Ile Ala Ser Gly Ser Met Leu Ile Lys Gly Ala Leu Gly 245 250 255 Ile Pro Ala Ala Ala Ala Leu Leu Pro Pro Phe Thr Leu Leu Val Ile 260 265 270 Leu Gln Leu Val Phe Gly Lys Lys Val Ala Ala Ile Arg Gln Ala Glu 275 280 285 Ala Ser Lys * 290 <210> 1668 <211> 971 <212> DNA <213> Escherichia coli O157:H7 <400> 1668 catgactggt atattaataa tgttgctatt taatgaaact cctggtttat ctgttttcca 60 taatgatgtc gccgcgccct gatcgccgtt ggccgaaatt ttaatggcag cctcagtccc 120 ttttggtggt tctgttagat ccaacacaaa ccctacacca ttatctgttt taccacgcaa 180 aatagtatta cttcctttaa ctaagtcact gctagaaaga tatacaacca tattccgcga 240 tgcttgtttt ttgtcgccga aaagattatc acatttcaac gtaattgttc cttccttact 300 gttcgccgca atctttccct gatttctgag ctggaacaag gcgatatcat ctacttttat 360 aacggtgttt tcaggcttac aggtcgtatt tttaggataa taggaaatat ttaacccaag 420 cgtaaatgta tcccccgcca gtttgctggt gagataattc acacaccagt taaacttcaa 480 tgccttacaa atacccaacc aaaaatcgat ggatgacgat gactcaccgc caatatttgc 540 aatcacggta tctgaaataa accaggtaga ttttctttct ccagtaaaat caggtgtgcc 600 tctggctatt ttaaccacat aaggtaatac tgcctgcgca ttgctggatt tcccaattgt 660 gtcgctggtt ttacctaaag actctatttt aacctttaat ttttcgccat taccaaaagg 720 cccaacttca acccaatcac tttggatatt tttataaact attttatccg tgctcgtatc 780 acaagatatc ccagtaaaca cgacactttt actaaaggaa gtttcattcg ctaaaatctc 840 cccaacatta ataccatctg taatatttaa tgatgcagta gtacgacacc cagcccaggt 900 aaaattagcc cacaatataa atattagtaa tattctattt ctgaacatca tatttcacct 960 ctcaccgaca g 971 <210> 1669 <211> 952 <212> DNA <213> Escherichia coli O157:H7 <400> 1669 gatggagctg attgcgtcgt ccagggcagc aagcgggttg gtcgttgcag aaccagcact 60 ggtagtctca gtagtgattt tacccgcgga gttcacattt acagcagtac caattgctgg 120 agcataatct ttattggtat cagtcgctga agcatacccg gcaacagtca cagagccgtt 180 atccttgtta acgctgtaag agactgtata gtcggcaacg ttagtgatac cacctttatc 240 atccacataa gacttcgcag catcactgga ttcacccgcg gtaaacccaa tagttttgct 300 cagtacaccg gaattaaagg taattgaaga tgtcgcggca gccgctttgg tttcgctcaa 360 tactacatct ttactcactg tagcctgata agtaatccca ccagggatta acggagctac 420 tggagtggtt gtcgcaggag ttgcttttgc gatggtatat tctgtgccat tgaatgtcag 480 agaggcaccg tcactacctt cgctcgctgc tttgagcagc gctttcatat cagctttagc 540 tgcgctacca gcgttgttag tcgtcaagtt gcctgcatcg tctacgtatg cctggcttcc 600 accgatggtg atattacctg ctgaatccgt ttcgaaagaa acagtaccat cttttgtggt 660 gtaagaacca ttaacagatt tacccacatc agcatgaagg gtggcagcta acgcatcacg 720 ttttgaagct gaatcagcag cctgcgccgc ggcgtctaca cccgtaccag cagtagattt 780 agtggtagta aaatcaccag atttagcgtt gtaagtataa tctacgccgc caactgtgac 840 tttatcgcca ttccctaatt tatcgaatgc agcatcggta gttaacaagg tattttcggt 900 tttcagatca taaagacctg tcgtggtgtt taacttcgcg ccagcagaag tt 952 <210> 1670 <211> 943 <212> DNA <213> Escherichia coli O157:H7 <400> 1670 ctctgtgtaa aaagcagttc aatggatttg gttgggaaaa ataacgcatt ttcgttttcc 60 ccgactaaag ggataaagcc cagcgattta taaaacgtat gggctttttc attcagcgcc 120 tcgacaaaaa gaccgtgaat acctaccgct aaagaggctg accagacgac tttcatggca 180 tgagcaacca gtgttgctcc ccatccctgc ccctgtaatg aacgatcaat tgccagacgc 240 ccaagagtaa cgctgggaat atttttgtag ggaatttttt tctgtttcga tttcgagggc 300 aatgcggctc gttcaaaaca actgccgcat aatgtgtaat atcccagcac ctgacgttct 360 ggagtgttgc gacaaaggat atacgctcgc agaattttgt tgcgatgttg acgaacgaga 420 tgtgtcgtca gaaagagatt taacgcttcc tcgccgcagt cgaatcgctg tagatcataa 480 tctgcatcat cggtcagaat ctctatcgtc agatcatcca taaattatta cattccctga 540 agacgttttg ccgcacgttt tagcttttca cctggtgacg gtggattact cagcgcatcc 600 atcacccgcg tccaggattc ctcattgagg atcacccgcc gatgctgttc aatcacttcc 660 gcagcccgct gcgaagcgct gttcaacata aattggctga cggactgatt agatatcgct 720 gccgcttcct caatcatact tttgtcatcg tcagttaaac gcagatcgat acgctgcttt 780 ttaacagcag acatgtgaac tctcctgctc cgtataatat gtacggtatg tcaccgtaca 840 ttaagcatat cctggattgt ttaatctttc tacaaccatt tcgacaaaca caaaaaaacc 900 cgatggcagt tcagcgcatc gggcattttc atttatctat ctg 943 <210> 1671 <211> 89 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(528..794) <400> 1671 Met Ser Ala Val Lys Lys Gln Arg Ile Asp Leu Arg Leu Thr Asp Asp 1 5 10 15 Asp Lys Ser Met Ile Glu Glu Ala Ala Ala Ile Ser Asn Gln Ser Val 20 25 30 Ser Gln Phe Met Leu Asn Ser Ala Ser Gln Arg Ala Ala Glu Val Ile 35 40 45 Glu Gln His Arg Arg Val Ile Leu Asn Glu Glu Ser Trp Thr Arg Val 50 55 60 Met Asp Ala Leu Ser Asn Pro Pro Ser Pro Gly Glu Lys Leu Lys Arg 65 70 75 80 Ala Ala Lys Arg Leu Gln Gly Met * 85 <210> 1672 <211> 935 <212> DNA <213> Escherichia coli O157:H7 <400> 1672 aaagtcgcag cacatgcaac ttgaagtatg acgagtatag ctttcttaaa gggggaaacg 60 gtattccccc ttagatgcgt ttcaatttgc ccgttacttc aacaaatcaa tcaaccgtaa 120 cagagccact aataactcca gtacggcaat gagcacggtt aacttttgtg tcagcgtgtc 180 catccgctct ccttattaag gagcgcaaca ccagcacctt acccttacac tgcctgtcga 240 tactggttta cgtatgttgg tacgaaacgt tgctctccgg atcagggcac cgcctgcggc 300 accacccgtc cggcagccag gacttaaaat tggtccgatc cggcacaacc tcccaacggg 360 caggattata aatctcactc actgaattgc aatggagtgt ggatatggtt ataatttatt 420 cgttggtacg aaatgttgca caatcagcaa gttagcgtca ctgtagtaaa taaaagaacc 480 tgcctcacca gcaggttttt ttattttctg cgatctactt tccagatatt tttttgccaa 540 tagcccacca taaatattca catcccggtc aaatggtgcg ttgaatataa aatcgatgaa 600 tttataaata aaaatgagtt atatgatgaa ttaataaaaa cagtaatcat tttattaaag 660 ggggaagcgg ttttccccct tagatgcgtt tcaatttgcc cgttacttca acaaatcaat 720 caaccgtaac agagctacta atagctccag tacagcaatg agcacggtta acttttgtgt 780 cagcgagtcc atccgctctc cttattaagg agcgcaacac cagcacctta cccttacact 840 gcctgtcgat actggtttac gtatgttgga ccacgatgtt gcactccgga tcagggcacc 900 acctgcagca ccccccgtcc ggtagccagg acttg 935 <210> 1673 <211> 935 <212> DNA <213> Escherichia coli O157:H7 <400> 1673 cgaaacacaa gtttgtgcta attatcgcct taaatgggcg aggcatcaag cgaggttgct 60 atttccgaca cggtggcggc gcatagccat tgttatctgc cggaaaggct tgtccagagc 120 acggtggcag cgcgttttgc gcctggcctt gtaattcaaa ggcggcaaag ccgattacac 180 cggtattacg cacatcgcct tgcgccgaat tggctgcgta ggaatcagca acgttggcga 240 actgaaaagc cgcttcggta tgtttatctt tgcggaatcc tttaatcgct aacgaatctc 300 cggcattcac aatatagccg ttgttattca gcgaaccttg cttgccgttc agcacatcca 360 ggccatcaac cgtagcaacg atctcgtagt tggtgttacg actgtaatta cggacatata 420 attgataatt cattccgact ctggcatgga caatatagcg tggttcatta ttagatgaat 480 cataaacacg cgtaataggt agagaattaa aattaccatc gcgaatagca tattccagtt 540 cgttaatacg aatgctataa acgcgatcgt agccggaagg aacattagtc gaataactaa 600 taacgatcat ctccgccgga tcgcgccagg ctcgctcagc agatacgccc tgaaccgttg 660 agtgcacatc cccaccccag gcggtgccga cattgcccga tgcactgcta ttatactgcg 720 cattactgga acaaccggcc agcagcacga ttaatgccac caacgcgctg cgtactttcc 780 attttttcat aaccgttccc tctgcattta attaatgcag cgattgtagg gagattattt 840 aataagaaaa gcagctaaat tatttttaag aatatataaa aagaaagcgg accgatttac 900 gtaaataaat cgacccgcca gcagaataat cttaa 935 <210> 1674 <211> 244 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(59..790) <400> 1674 Met Lys Lys Trp Lys Val Arg Ser Ala Leu Val Ala Leu Ile Val Leu 1 5 10 15 Leu Ala Gly Cys Ser Ser Asn Ala Gln Tyr Asn Ser Ser Ala Ser Gly 20 25 30 Asn Val Gly Thr Ala Trp Gly Gly Asp Val His Ser Thr Val Gln Gly 35 40 45 Val Ser Ala Glu Arg Ala Trp Arg Asp Pro Ala Glu Met Ile Val Ile 50 55 60 Ser Tyr Ser Thr Asn Val Pro Ser Gly Tyr Asp Arg Val Tyr Ser Ile 65 70 75 80 Arg Ile Asn Glu Leu Glu Tyr Ala Ile Arg Asp Gly Asn Phe Asn Ser 85 90 95 Leu Pro Ile Thr Arg Val Tyr Asp Ser Ser Asn Asn Glu Pro Arg Tyr 100 105 110 Ile Val His Ala Arg Val Gly Met Asn Tyr Gln Leu Tyr Val Arg Asn 115 120 125 Tyr Ser Arg Asn Thr Asn Tyr Glu Ile Val Ala Thr Val Asp Gly Leu 130 135 140 Asp Val Leu Asn Gly Lys Gln Gly Ser Leu Asn Asn Asn Gly Tyr Ile 145 150 155 160 Val Asn Ala Gly Asp Ser Leu Ala Ile Lys Gly Phe Arg Lys Asp Lys 165 170 175 His Thr Glu Ala Ala Phe Gln Phe Ala Asn Val Ala Asp Ser Tyr Ala 180 185 190 Ala Asn Ser Ala Gln Gly Asp Val Arg Asn Thr Gly Val Ile Gly Phe 195 200 205 Ala Ala Phe Glu Leu Gln Gly Gln Ala Gln Asn Ala Leu Pro Pro Cys 210 215 220 Ser Gly Gln Ala Phe Pro Ala Asp Asn Asn Gly Tyr Ala Pro Pro Pro 225 230 235 240 Cys Arg Lys * <210> 1675 <211> 893 <212> DNA <213> Escherichia coli O157:H7 <400> 1675 aatatttctc atgaaactta tcacagatgg gtgttgaaaa aaggaataac tttttccagc 60 gcctcctgaa ctgcttccgg tttgtcatac agttcataat gtgagaaatc gggtaatgaa 120 actaactgac gatcctgcga aaccatcgcc cggccataga cttccagtcc atcacgataa 180 gcaccgaagg caccgacttt ttcaccaact actaccatca ccggctgagt cagtaacact 240 tcagtaaatg cgaaggcatc ccaggccagc gttttctgtg catgtgagaa caacattttt 300 gtcgcacctc ccggttgttg cccgcgtggt gttttatagt agtcagttgc ttcataaaca 360 tcgcgttcgg tcagtccatg ggcttttgct gcatccaggc tggcgggaag taattcgttg 420 atctgtaatt ctccaccacg agcctctttg gttcgttgcg acgccattgc attcaatgcg 480 ccaatcggat cgtaattgct gaaaccttcc cgaaaaagac gcccgatatt aacacccgta 540 atactcacta cagctttaat tcgtttttct gtcagcgcgg cattaatggc atagccaccc 600 ccccccacac acacccagca cgccaatgcg ttcagcatca acatatggca gagttactgc 660 ataatcgata acacggctaa tatcctctac gcgctgtgtc ggatcttcta tccaacgagg 720 ctccccacca gattctccct ggaaactggc gtcataagcg agaacgacat agcctttttc 780 agccaatgcc ttgccataga tattgccaga cgtctgctcc ttacaactgc caaaaggatg 840 gacgctgata atcgccggat actgttttga ctcatcaaaa tttggtggaa act 893 <210> 1676 <211> 92 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(21..296) <400> 1676 Met Leu Phe Ser His Ala Gln Lys Thr Leu Ala Trp Asp Ala Phe Ala 1 5 10 15 Phe Thr Glu Val Leu Leu Thr Gln Pro Val Met Val Val Val Gly Glu 20 25 30 Lys Val Gly Ala Phe Gly Ala Tyr Arg Asp Gly Leu Glu Val Tyr Gly 35 40 45 Arg Ala Met Val Ser Gln Asp Arg Gln Leu Val Ser Leu Pro Asp Phe 50 55 60 Ser His Tyr Glu Leu Tyr Asp Lys Pro Glu Ala Val Gln Glu Ala Leu 65 70 75 80 Glu Lys Val Ile Pro Phe Phe Asn Thr His Leu * 85 90 <210> 1677 <211> 889 <212> DNA <213> Escherichia coli O157:H7 <400> 1677 gtatagcgtt tttatgtaca ctctttatac tgtatataaa atcgcactac aggctcatga 60 atatgaaacc ggaaagcaaa gaagcgccaa tcaatatcag agcgaaagcc tcacagcgtg 120 acctgattga tatggcagcg aatctggtcg caaaatcgcg cactgatttt atgctggatg 180 ccgcatgccg tgaagcgcaa gacatcttat tagatcaacg actattcatc cttgatgacg 240 agcaatacga tgcgtttctc gctgccctgg acgcccccat cactgctgag cgtcaggcca 300 aaattaacgc gttgatgaat cgtaaatcgc catgggaata acggctccta ctcccctaac 360 gtctgaacat aatctggctg acttttgctg ttccgatcac gggatgaatg aatggctaaa 420 aaagaaagcg ttaaaaaatc acagctccgg tctgtctcgt gtttacgtta tctgtattgc 480 caatacccgc caggtaatcg gctattactg cctttctaca ggcagtattc aacgtaattt 540 ggcccctgga gccatgcgac gtaatgctcc cgaatcgttg cctgttgtcg tattaggcag 600 actggcaatt gatcaagcct gggcaggtaa agggttgggc gtcgcattgt tgaaagatgc 660 agtctatcgc acaatgtcca tagctcaaca ggtaggggtt cgtgcgctca ttgttcatgc 720 cttagacgat tcagtacgca atttctatct gaagtatgcc tttgtacctt caccattcca 780 gtcacttacc ttactgtatc ccattactct ggagtaattt acctctaccg gatagtcaca 840 ctgatgagtc tgatccggga gggatttcaa tcagtgagtt tggttatca 889 <210> 1678 <211> 95 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(57..341) <400> 1678 Met Asn Met Lys Pro Glu Ser Lys Glu Ala Pro Ile Asn Ile Arg Ala 1 5 10 15 Lys Ala Ser Gln Arg Asp Leu Ile Asp Met Ala Ala Asn Leu Val Ala 20 25 30 Lys Ser Arg Thr Asp Phe Met Leu Asp Ala Ala Cys Arg Glu Ala Gln 35 40 45 Asp Ile Leu Leu Asp Gln Arg Leu Phe Ile Leu Asp Asp Glu Gln Tyr 50 55 60 Asp Ala Phe Leu Ala Ala Leu Asp Ala Pro Ile Thr Ala Glu Arg Gln 65 70 75 80 Ala Lys Ile Asn Ala Leu Met Asn Arg Lys Ser Pro Trp Glu * 85 90 <210> 1679 <211> 162 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(332..817) <400> 1679 Met Gly Ile Thr Ala Pro Thr Pro Leu Thr Ser Glu His Asn Leu Ala 1 5 10 15 Asp Phe Cys Cys Ser Asp His Gly Met Asn Glu Trp Leu Lys Lys Lys 20 25 30 Ala Leu Lys Asn His Ser Ser Gly Leu Ser Arg Val Tyr Val Ile Cys 35 40 45 Ile Ala Asn Thr Arg Gln Val Ile Gly Tyr Tyr Cys Leu Ser Thr Gly 50 55 60 Ser Ile Gln Arg Asn Leu Ala Pro Gly Ala Met Arg Arg Asn Ala Pro 65 70 75 80 Glu Ser Leu Pro Val Val Val Leu Gly Arg Leu Ala Ile Asp Gln Ala 85 90 95 Trp Ala Gly Lys Gly Leu Gly Val Ala Leu Leu Lys Asp Ala Val Tyr 100 105 110 Arg Thr Met Ser Ile Ala Gln Gln Val Gly Val Arg Ala Leu Ile Val 115 120 125 His Ala Leu Asp Asp Ser Val Arg Asn Phe Tyr Leu Lys Tyr Ala Phe 130 135 140 Val Pro Ser Pro Phe Gln Ser Leu Thr Leu Leu Tyr Pro Ile Thr Leu 145 150 155 160 Glu * <210> 1680 <211> 866 <212> DNA <213> Escherichia coli O157:H7 <400> 1680 tatataatgt actttgtgtt catcattgta aagtacttta agtacatttt atgtataaaa 60 aaatgagacg ggataaagtg aagcacaaac ccggaggggg acgctaccgg atttatgctg 120 gtttaagagg ctttttgttt tttctttcgt gctaactctt cgtaaattgc attgtacttc 180 tgttttttct cctcaagagt ttttaaaagt tcatctgtct cactgtcagg gagctcgtcc 240 agaaggtcaa tgatgatttt ttgtcttgga tttaactcct gatagaaacg tatctgtcca 300 ctttcttctg tatcctctcc caaaagatag gttggtgttg ttccaatgag tgttgctaat 360 tcccttaatt tctctcggcg aggaattgtt tcaccattaa accatttgct aaccgctttt 420 ggtgttaatt tcattcgacg ggcaatttct gcctgccttc catgttgttc ataaccagcg 480 ttttcacagg ctagcgcaag cctactggcg aactctttac gcgctttatc ttcatgaacc 540 ataagttcaa tgatattcgc tcttgaatgt actgtcagtt ctgttatagc atgtactcaa 600 agttcacatt gtgagggtga tatgaaccag aaaacacttg aagatgtaat caaaactgtt 660 cgcgtttctg ttgtggccga cgtttgtggt gtcagccaaa gagcaatcta caaatggatg 720 gataacggta aattgcctcg cacagaatat accggcgaaa caaattacgc tgaaaaaatc 780 gctcatgcat caaacggatt attttctgcc gatgcaattt taactattgg cagaaataaa 840 actactacga aaaagctgat gggagt 866 <210> 1681 <211> 104 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(123..434) <400> 1681 Met Lys Leu Thr Pro Lys Ala Val Ser Lys Trp Phe Asn Gly Glu Thr 1 5 10 15 Ile Pro Arg Arg Glu Lys Leu Arg Glu Leu Ala Thr Leu Ile Gly Thr 20 25 30 Thr Pro Thr Tyr Leu Leu Gly Glu Asp Thr Glu Glu Ser Gly Gln Ile 35 40 45 Arg Phe Tyr Gln Glu Leu Asn Pro Arg Gln Lys Ile Ile Ile Asp Leu 50 55 60 Leu Asp Glu Leu Pro Asp Ser Glu Thr Asp Glu Leu Leu Lys Thr Leu 65 70 75 80 Glu Glu Lys Lys Gln Lys Tyr Asn Ala Ile Tyr Glu Glu Leu Ala Arg 85 90 95 Lys Lys Lys Gln Lys Ala Ser * 100 <210> 1682 <211> 855 <212> DNA <213> Escherichia coli O157:H7 <400> 1682 gaccagactc atcacaagac aagtcacgca gtaaatcttc aatctggata gtgaggatat 60 ccattgcctc atacgcatcc tgtgcaattc gcgccgccat tgcgccttcc ggttcaccac 120 gcagaatttc agccgctgcc tgtacgccag ccacaatcat ttcaggtgtt aacatttggc 180 gaagaaaagc gcgattatca gaggaccagc catctttatg gcctaatgga tgcccccagc 240 ctatccattc ttgcgaccat aacggattgg cttctatggg ataaattaga tgcgcggcat 300 actgaatagc acacaccgct tttcctggcg tatccagcgc ccaccagcgc gaccagagag 360 aacgaattaa cggcgcggcc ccacccagag tattgaacac cgccagccag caaagaacgt 420 tattgaaacc acgctcgtta tccatacgct gcaacgcggt gtccagtaaa aattgccgta 480 cctgctggcg ttgggaagca ttcatcatct cctgccagag atagggccga cacaatgcct 540 tcattaagga ttcttcgaag tgatcaccat aaccgccagc taaaacggtt tcatgccatt 600 gcgccaggca gagcggaaac agatagcgaa acaactctat ttgcatcggt tcgttataaa 660 cgagattgag tacatagtaa gcactcaaat cccattcgct gatctgctgc cactctttag 720 ccgccagcgc cttgagttcg gcatctgcgt aatcaaattc cgtttcccat acacagagca 780 ctggcggctc atcaccaaaa atatggcgac agtgttcacg tagcgtttcc ggttccttcc 840 gacgcttttt cattt 855 <210> 1683 <211> 841 <212> DNA <213> Escherichia coli O157:H7 <400> 1683 ctcctgaatc ggactgtctt tcactccctc tctccactac attcccttgc tcatttagca 60 tctgatatgg agtcatcagt gaacaaggcc ccctctttaa ttgccgctat cgtcctcgga 120 ctggggatta gcgcctgtgg ttattttgtt ggcgatggtg ttaaacattt aaaaaccaac 180 aaccgttatg tcaatgtgcg cgggctttct gaaaaagaag ttcgcgcaga tacggcggaa 240 ttaacaattg cgattaactt taagggtaat gttcccggcg aactgttccc gaaactggaa 300 gaagcgcaga aaaaaattgt tgccgaactc aatgctcagg ggattaacga gaaagagata 360 attctgggcc aatggacaag caagcgaaca gattcctttt atctgaaaga tgatcccaca 420 atgccacgct ataacgcaga cgggtcagtg acgataaaaa cccataatgt tgctgctgtc 480 gaaaaagtcg tcgcgaaatt aaacgaactg caagtcgcta cggatggcgc tatcgctgag 540 agcaaagtcg cctatcgctt taatggtatt ggcgcactgc gcgctgagat gattgctgcc 600 gccaccaaag atgcacgcaa cgccgcacta caatttgcaa cggactcagg tagccaggtg 660 gggtcaatta gcgatgcctc acaaggcgta ttccagatct ttgccagtgg cagtgatgaa 720 gatgatccta cggcgattaa taaaacggta cgcgtagtca cgaccgtaac ctatgcgttg 780 caggattaac cacttttctc cggcgggaca ctaatccctc cgtcctgccg gacttttctc 840 a 841 <210> 1684 <211> 237 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(79..789) <400> 1684 Val Asn Lys Ala Pro Ser Leu Ile Ala Ala Ile Val Leu Gly Leu Gly 1 5 10 15 Ile Ser Ala Cys Gly Tyr Phe Val Gly Asp Gly Val Lys His Leu Lys 20 25 30 Thr Asn Asn Arg Tyr Val Asn Val Arg Gly Leu Ser Glu Lys Glu Val 35 40 45 Arg Ala Asp Thr Ala Glu Leu Thr Ile Ala Ile Asn Phe Lys Gly Asn 50 55 60 Val Pro Gly Glu Leu Phe Pro Lys Leu Glu Glu Ala Gln Lys Lys Ile 65 70 75 80 Val Ala Glu Leu Asn Ala Gln Gly Ile Asn Glu Lys Glu Ile Ile Leu 85 90 95 Gly Gln Trp Thr Ser Lys Arg Thr Asp Ser Phe Tyr Leu Lys Asp Asp 100 105 110 Pro Thr Met Pro Arg Tyr Asn Ala Asp Gly Ser Val Thr Ile Lys Thr 115 120 125 His Asn Val Ala Ala Val Glu Lys Val Val Ala Lys Leu Asn Glu Leu 130 135 140 Gln Val Ala Thr Asp Gly Ala Ile Ala Glu Ser Lys Val Ala Tyr Arg 145 150 155 160 Phe Asn Gly Ile Gly Ala Leu Arg Ala Glu Met Ile Ala Ala Ala Thr 165 170 175 Lys Asp Ala Arg Asn Ala Ala Leu Gln Phe Ala Thr Asp Ser Gly Ser 180 185 190 Gln Val Gly Ser Ile Ser Asp Ala Ser Gln Gly Val Phe Gln Ile Phe 195 200 205 Ala Ser Gly Ser Asp Glu Asp Asp Pro Thr Ala Ile Asn Lys Thr Val 210 215 220 Arg Val Val Thr Thr Val Thr Tyr Ala Leu Gln Asp * 225 230 235 <210> 1685 <211> 840 <212> DNA <213> Escherichia coli O157:H7 <400> 1685 tgggaaaagc tcgaggctgc tcgaagaaat aaaaatcata ggacaaggtg atatgtattt 60 tcgcgattgt gttgggaaca agggataaag tattgcactt ggtgatatac tttaataaca 120 ggacctcaac gatatacgcg tgtttaaaac caaatggttt gcaagggaag ccaggtctca 180 tgcaataaca gatgaagagt tgtgccgggc cattttagaa acagaacaag gtaaagctga 240 tgcacttggc ggtggcgttt ttaaaaagcg ccttcaccaa aatcgtgagc gtgcaattat 300 tctggcgaaa ggggtaagca attggtttta cacgttttta tatgcaaaac aggatatgtc 360 gaacatcaat agtcaggaac tggctgggtt tcgtgaaatt gcaaagcatt atgccttcct 420 gacgaaagcc caactaacag caatgattaa cactaaagaa ctgacagaga tctgctatga 480 ctgcaaaaac taaatttaaa agtcctgcat ttgaggctat tcacagcgca gcggctggat 540 tgtccagcgt caatgctatt tctgctgaaa cgatgcgtac ttttgacaaa gcctgcctga 600 ccagcgtgca agacttacaa cctgttgaga taaaagcact gcgggaaaaa ttaaaagtga 660 gtcagcccgt cttcgctcac tatctcaata ccagcgtttc aactgtacaa aaatgggaaa 720 gtggcgctaa acgccccaat ggcatttcat taaaactgct cagcattgtg caaaaacacg 780 ggttggaggt gctgctgtaa atagaacgta gataatgcgt tcacctactg tcagttccga 840 <210> 1686 <211> 118 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(140..493) <400> 1686 Val Phe Lys Thr Lys Trp Phe Ala Arg Glu Ala Arg Ser His Ala Ile 1 5 10 15 Thr Asp Glu Glu Leu Cys Arg Ala Ile Leu Glu Thr Glu Gln Gly Lys 20 25 30 Ala Asp Ala Leu Gly Gly Gly Val Phe Lys Lys Arg Leu His Gln Asn 35 40 45 Arg Glu Arg Ala Ile Ile Leu Ala Lys Gly Val Ser Asn Trp Phe Tyr 50 55 60 Thr Phe Leu Tyr Ala Lys Gln Asp Met Ser Asn Ile Asn Ser Gln Glu 65 70 75 80 Leu Ala Gly Phe Arg Glu Ile Ala Lys His Tyr Ala Phe Leu Thr Lys 85 90 95 Ala Gln Leu Thr Ala Met Ile Asn Thr Lys Glu Leu Thr Glu Ile Cys 100 105 110 Tyr Asp Cys Lys Asn * 115 <210> 1687 <211> 108 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(477..800) <400> 1687 Met Thr Ala Lys Thr Lys Phe Lys Ser Pro Ala Phe Glu Ala Ile His 1 5 10 15 Ser Ala Ala Ala Gly Leu Ser Ser Val Asn Ala Ile Ser Ala Glu Thr 20 25 30 Met Arg Thr Phe Asp Lys Ala Cys Leu Thr Ser Val Gln Asp Leu Gln 35 40 45 Pro Val Glu Ile Lys Ala Leu Arg Glu Lys Leu Lys Val Ser Gln Pro 50 55 60 Val Phe Ala His Tyr Leu Asn Thr Ser Val Ser Thr Val Gln Lys Trp 65 70 75 80 Glu Ser Gly Ala Lys Arg Pro Asn Gly Ile Ser Leu Lys Leu Leu Ser 85 90 95 Ile Val Gln Lys His Gly Leu Glu Val Leu Leu * 100 105 <210> 1688 <211> 822 <212> DNA <213> Escherichia coli O157:H7 <400> 1688 ttttgagcaa ggtttatgaa ggttatttat gtgatgatga tcacaaccga agcgattttt 60 agccctcggt tgtgtaactc atttaaaaat tatattcata ctataaatat taaataacaa 120 tatagcaata tggtgtgtta tttatttctt taagtaaaac gtgtttttta cgagatttag 180 taagataaaa tttctcatct aaatagcaat cgatgagaga gtccagcctt tccctgtcta 240 tcataggggt gatacccaag gtccagaaac tgcgtaaatc gagttcggaa cgttttattt 300 ttgcgctttt ttctaagtct gcgatcatat ttttaacaca actggtcgcg tctctgtttt 360 gttttatttc aagcgcgata tagctatctt gtgcccagcc ttttttacgt agtaagaaat 420 ctgtgcgtag tgtcgggcgc tcaggttttt tgcgcatatc acaggaaagt gcttgttcac 480 gccaccattc atggtctgtt gagcagagca tattagcaaa ctctacctgg aaccacactt 540 cccaaccggt gatattgttt tggtcaataa tattaagctt ttggcaaata tcctcacgtt 600 caaaaaagag atgtaatagc gttgagagat gatcgaagtc acggtttaac atttcagatg 660 tcctttctta aaattccaca ctctataaaa tatttcgttc aaaatagata caattcgtgt 720 gaaaaaaata agaaaagaaa atgtatcaat aagtggttat tgtatttttg aacaaaaatt 780 aaaaaaagtg aggtaaaatt aaccagtttc aagtcgctac ct 822 <210> 1689 <211> 181 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(110..652) <400> 1689 Met Leu Asn Arg Asp Phe Asp His Leu Ser Thr Leu Leu His Leu Phe 1 5 10 15 Phe Glu Arg Glu Asp Ile Cys Gln Lys Leu Asn Ile Ile Asp Gln Asn 20 25 30 Asn Ile Thr Gly Trp Glu Val Trp Phe Gln Val Glu Phe Ala Asn Met 35 40 45 Leu Cys Ser Thr Asp His Glu Trp Trp Arg Glu Gln Ala Leu Ser Cys 50 55 60 Asp Met Arg Lys Lys Pro Glu Arg Pro Thr Leu Arg Thr Asp Phe Leu 65 70 75 80 Leu Arg Lys Lys Gly Trp Ala Gln Asp Ser Tyr Ile Ala Leu Glu Ile 85 90 95 Lys Gln Asn Arg Asp Ala Thr Ser Cys Val Lys Asn Met Ile Ala Asp 100 105 110 Leu Glu Lys Ser Ala Lys Ile Lys Arg Ser Glu Leu Asp Leu Arg Ser 115 120 125 Phe Trp Thr Leu Gly Ile Thr Pro Met Ile Asp Arg Glu Arg Leu Asp 130 135 140 Ser Leu Ile Asp Cys Tyr Leu Asp Glu Lys Phe Tyr Leu Thr Lys Ser 145 150 155 160 Arg Lys Lys His Val Leu Leu Lys Glu Ile Asn Asn Thr Pro Tyr Cys 165 170 175 Tyr Ile Val Ile * 180 <210> 1690 <211> 760 <212> DNA <213> Escherichia coli O157:H7 <400> 1690 gatgcggaac ggccccgccg ggacctgggt ttcgtagatg acgcggccca actggctgac 60 ggtcactttc gcggtggtgt gcgccacgcc ggagatatcc ggcgcatagc cgcgcagatt 120 cggcggcaac atttgatcgt cggtgctgat actgccaccc acgtagttaa agccgtcgaa 180 aatatcagaa ttcaggtagt cttcgccaag gccaagtttg gcttttagcg acggtaaggc 240 tcgccaggcg tagtagcggc tccactccca gtttttttgc gtgtcatcac cgttgataac 300 atcgtcatca ttgcttttac tatgcaaata atcagtctgc cagtcggcac gaagacgcca 360 tgcgccgagg ttcaccccaa ccgtcccgtt accgctaatt tcattgctgt catccccgcc 420 attttcttca tgtcgtgtct gggcggtaat actgtagtca gcaattaaac cagatatacc 480 gtcatcccag cgtgaaggcg gatcccagtt gatgtcggta tattcaaggt aagcctgggg 540 taatgaaatg actaacgctg actgactcag gtcagcttta atatcaatgc cttccagttg 600 accgggtttc aggcatttgc cgtcgtggat ccattgcagg ttttttgcca catcctcttt 660 taagccaaac tgcgcgacca gttcaggcgt caggcaggca taggttttac tggcatcgtt 720 ctcagaggcg taccagtaaa tatcgtattc ttccgtcagc 760 <210> 1691 <211> 746 <212> DNA <213> Escherichia coli O157:H7 <400> 1691 aaaacatcaa atgcgcaggt tcaaactgcg catttgattt atacaaaatt tagtataatc 60 taaggatgga gtaatgagaa aaaagctggc ttttcttgat accagtcttg acgatttacg 120 cgcatttcca gaatcgtctc gacaggaaat tggctatcaa ctcgacagga tccaacaagg 180 gttaaaccca tacgactgga aacctttttc aactatcggc cctggtgtgc gagagattcg 240 tactcgcgat gctgatggga tctatcgcgt catgtatgtc gcaaaatttg aagaagcggt 300 ttacgtattg cattgttttc aaaagaaaac acagactacc agtcaatcgg atattgattt 360 agccaaacga cgctataaag aacttgttca ggagcggaaa aatgaaaatt gaaacctttg 420 atagtgtgtg ggatgcggtg agtgacaccc ctgaacaagc ggaaaatatg cggatccgtg 480 ccgagcttgt aacgatcatt aataactgga ttgaacaaca agggtttagc caggctcagg 540 cagcttctgc tttaggggtc actcaacctc gcatctctga acttgccaga ggtaaaatcc 600 agatctttag tatcgataaa ttgatcacca tgatggctca tgcaggacta catattcaac 660 gtattgaagt tcaatatcca catgctgctt agtgctataa atacagatgg cgacaaattg 720 atgccgccat ctatataact tgtctt 746 <210> 1692 <211> 113 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(74..412) <400> 1692 Met Arg Lys Lys Leu Ala Phe Leu Asp Thr Ser Leu Asp Asp Leu Arg 1 5 10 15 Ala Phe Pro Glu Ser Ser Arg Gln Glu Ile Gly Tyr Gln Leu Asp Arg 20 25 30 Ile Gln Gln Gly Leu Asn Pro Tyr Asp Trp Lys Pro Phe Ser Thr Ile 35 40 45 Gly Pro Gly Val Arg Glu Ile Arg Thr Arg Asp Ala Asp Gly Ile Tyr 50 55 60 Arg Val Met Tyr Val Ala Lys Phe Glu Glu Ala Val Tyr Val Leu His 65 70 75 80 Cys Phe Gln Lys Lys Thr Gln Thr Thr Ser Gln Ser Asp Ile Asp Leu 85 90 95 Ala Lys Arg Arg Tyr Lys Glu Leu Val Gln Glu Arg Lys Asn Glu Asn 100 105 110 * <210> 1693 <211> 97 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(402..692) <400> 1693 Met Lys Ile Glu Thr Phe Asp Ser Val Trp Asp Ala Val Ser Asp Thr 1 5 10 15 Pro Glu Gln Ala Glu Asn Met Arg Ile Arg Ala Glu Leu Val Thr Ile 20 25 30 Ile Asn Asn Trp Ile Glu Gln Gln Gly Phe Ser Gln Ala Gln Ala Ala 35 40 45 Ser Ala Leu Gly Val Thr Gln Pro Arg Ile Ser Glu Leu Ala Arg Gly 50 55 60 Lys Ile Gln Ile Phe Ser Ile Asp Lys Leu Ile Thr Met Met Ala His 65 70 75 80 Ala Gly Leu His Ile Gln Arg Ile Glu Val Gln Tyr Pro His Ala Ala 85 90 95 * <210> 1694 <211> 716 <212> DNA <213> Escherichia coli O157:H7 <400> 1694 gcaaatctga gcctgacgca agcatcgggc agaaattaat cgcaacgcgc agattgcgag 60 ctgcattcca cgaaatttgt aaggttgtga agatagcgtt tttcaccgga atcaggttaa 120 caaatcagcg ctctctctgt tgctgagcat ccggagttat tcgatggtga tactccaatt 180 acagaggatg ttttatggac actacccttc cctttctaat tttgtacgct tgtttatcag 240 ccctactttt tttctgggat gcaaagcatg gcttgttacc tgacagattt acgtgcccgt 300 tactctggtc aggtcttttg ttctatcaag tttgtcatcc tgatggttta gccgatgcgt 360 tatggggggc aattattggt tacggcacat tcgctgtcat ttactggggg tatcgcatac 420 tgcgccataa agaaggatta ggctatggtg atgtgaagtt tctcgccgcc cttggcgcct 480 ggcattcatg ggccttctta ccacgactgg ttttccttgc tgcctcattc gcttgcggag 540 ccgtagttat tggtctgctc atgagaggaa aagaatcatt aaaaaacccg ctgccttttg 600 ggccatttct ggcggctgcg ggtttcgtta taggctggga tagtttgctg ataggccgtt 660 aatcattaac tttaatttgt gattgcaggt aattttgtag gccgatttta ccgatg 716 <210> 1695 <211> 156 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(195..662) <400> 1695 Met Asp Thr Thr Leu Pro Phe Leu Ile Leu Tyr Ala Cys Leu Ser Ala 1 5 10 15 Leu Leu Phe Phe Trp Asp Ala Lys His Gly Leu Leu Pro Asp Arg Phe 20 25 30 Thr Cys Pro Leu Leu Trp Ser Gly Leu Leu Phe Tyr Gln Val Cys His 35 40 45 Pro Asp Gly Leu Ala Asp Ala Leu Trp Gly Ala Ile Ile Gly Tyr Gly 50 55 60 Thr Phe Ala Val Ile Tyr Trp Gly Tyr Arg Ile Leu Arg His Lys Glu 65 70 75 80 Gly Leu Gly Tyr Gly Asp Val Lys Phe Leu Ala Ala Leu Gly Ala Trp 85 90 95 His Ser Trp Ala Phe Leu Pro Arg Leu Val Phe Leu Ala Ala Ser Phe 100 105 110 Ala Cys Gly Ala Val Val Ile Gly Leu Leu Met Arg Gly Lys Glu Ser 115 120 125 Leu Lys Asn Pro Leu Pro Phe Gly Pro Phe Leu Ala Ala Ala Gly Phe 130 135 140 Val Ile Gly Trp Asp Ser Leu Leu Ile Gly Arg * 145 150 155 <210> 1696 <211> 687 <212> DNA <213> Escherichia coli O157:H7 <400> 1696 ggtgttttaa atccgttctg ttaaaaaaac cgtggcgtat ttgcgctgcg gttttttttg 60 cctgtttcac aggcaactga atacggtttg gttgtagaaa gcgttctgac atatactttg 120 tattaatagt taatacgtgg agatcgctta tgcgcaaaat tacctcagta agcgttggcg 180 aacaattaga tagttttatt acccggatgg tccagtctgg tcgttatggc tcggccagtg 240 aagtaatgcg ttcggcactt cgtctattgg aacaacaaga atccagggat gaagctgtca 300 gaaatgctgt tattgaaggt cttgagagcg gtgaaagttc gatgacgctt cgtgatatcg 360 cagcagaaag gaagcaaaaa catcgtgtat aagcttagcg gaaaagctgt tgaagatttc 420 agagggatct atgactacac gctgggaaag tttggtgatg agcaggcgga tcgctatacc 480 gactctctcg gcacttttct ggatacactc tctcaaatgc ccgagatagg gcaagactat 540 gatgcgattc cagaggtaaa gaagatcgca tttaggtttc acactgttta ttacgttata 600 agagtcgatg acattctcat tgcgcgcatt cttcatcagt tgatggaacc tcgccgtcac 660 tggtaatgtg agaatttctt gactcag 687 <210> 1697 <211> 81 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(150..392) <400> 1697 Met Arg Lys Ile Thr Ser Val Ser Val Gly Glu Gln Leu Asp Ser Phe 1 5 10 15 Ile Thr Arg Met Val Gln Ser Gly Arg Tyr Gly Ser Ala Ser Glu Val 20 25 30 Met Arg Ser Ala Leu Arg Leu Leu Glu Gln Gln Glu Ser Arg Asp Glu 35 40 45 Ala Val Arg Asn Ala Val Ile Glu Gly Leu Glu Ser Gly Glu Ser Ser 50 55 60 Met Thr Leu Arg Asp Ile Ala Ala Glu Arg Lys Gln Lys His Arg Val 65 70 75 80 * <210> 1698 <211> 94 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(385..666) <400> 1698 Val Tyr Lys Leu Ser Gly Lys Ala Val Glu Asp Phe Arg Gly Ile Tyr 1 5 10 15 Asp Tyr Thr Leu Gly Lys Phe Gly Asp Glu Gln Ala Asp Arg Tyr Thr 20 25 30 Asp Ser Leu Gly Thr Phe Leu Asp Thr Leu Ser Gln Met Pro Glu Ile 35 40 45 Gly Gln Asp Tyr Asp Ala Ile Pro Glu Val Lys Lys Ile Ala Phe Arg 50 55 60 Phe His Thr Val Tyr Tyr Val Ile Arg Val Asp Asp Ile Leu Ile Ala 65 70 75 80 Arg Ile Leu His Gln Leu Met Glu Pro Arg Arg His Trp * 85 90 <210> 1699 <211> 665 <212> DNA <213> Escherichia coli O157:H7 <400> 1699 cattgatgtg cagatattag aattgtcgta atgttatata catggcgtat tttattctta 60 ctggttctac acatgttaat cgcatctgat tgatcagttc accttaataa gtttaataaa 120 tcgtactgca catagtacag tacgatggtg gttatataat tgatttacat gaagaatggc 180 ttgtcgccat cagtcccggg ttgattgatg cctatattct caccaatgtg tttctcaggt 240 ttatcgatga tatctgtaat taatgctgcg acactcttag gtgatacgat cgtacctttg 300 aatggttcat tgcgtgaggt aagctcataa tcaataatat cttcatccgt cagccaggca 360 gggcgaagaa ttgtatattc cagtccagaa gcctcaattg catccgcagc cctgcggaat 420 ggttttaggg gctcaccaat aactgcatta ttccattcgc caaattttcc tggaacttca 480 tcataaatgc cgagggaaag aacaaagatc agacgtttaa catcacaggc tttcatcgca 540 gcgatcactg aatttgcctg aatatctaaa tcttcccccg taaggttggc atacacaata 600 tcctgtccct gcatggcctg cttcagtgct gcatgattca gtacatcccc cataataatc 660 tggct 665 <210> 1700 <211> 653 <212> DNA <213> Escherichia coli O157:H7 <400> 1700 tcattctgtt tcgacaaaaa agcacagttt atccttttag cggcttcgtt tcgacattcc 60 ggacgatgga tttcacctgt aagtatacgt tcttctttcc atttatttaa ttcgagcatc 120 cagttaagtt gatttttttc tggatgttgc tgtatggatt gtggttttat tttgttaaat 180 attgaaggga atttcataac tgctccatag taatacaatg tttttctgat ttatcaccct 240 tgataaacca ggatgtgttt tataactctg ttgtaaagga ttggcttaac caattattgg 300 atgttggacc ataacctaag gaaggtttac tctcattatg aatataataa cagacgggtg 360 tgcccgttgg gtccttgagt cccgagtgtg aggatagaga agaggaattt gacttatagt 420 cactaacccc gtacatgcga cgcataggca gaatagcttt tagttctgcg tcagaaaata 480 ttgtttcttc ttctattaag gcggaatctc tggaataata ttttgatcta taacgaatag 540 acattgagtc attgtctttt atataattac cttctgaatt atcgcttact tctacaagat 600 gttcatcact ggtatcgata tttgtgattg ccagattata agataaatca atg 653 <210> 1701 <211> 645 <212> DNA <213> Escherichia coli O157:H7 <400> 1701 ttagaattcc ggcatcactg atacgtgcag atatccgtgt atactagacg tataaattgt 60 acaggagcac gatatcatga ctgcaaaacg taccacacaa agtgtgaccg tcaccgtcga 120 ccgtgagtta gtcaatcgcg ctcgtgatgc aggcttaaat atgagcgcca cccttacggt 180 tgcgctcaat gctgaactta aaaaacatgc agcaacacgt tggcgtgaag agaacgctga 240 agctatcgct gcgttaaatc aattggctga tgaaaccgga tgtttctctg atgagtaccg 300 gagcttctag cgatgcaatt tacggtatac cgcagtcgca gcaggaacgc cgcgtttccc 360 tttgttatcg atgttaccag cgacattatt ggtgtgatta atcgccgtat tgttattcca 420 ttaacaccta ttgaacgatt tagccgtatt cgcccaccag aacggcttaa cccaatcctt 480 ttactggtag acggcaaaga atatgtgctc atgacgcatg agactgcaac tgttccagtt 540 aacgcgctgg gaacgaaatt ttgcgatgcc agcgcgcacc gaacgttgat taaaggagca 600 ttagatttta tgctcgacgg gatttaagac gcgaccgcct ctccc 645 <210> 1702 <211> 78 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(77..310) <400> 1702 Met Thr Ala Lys Arg Thr Thr Gln Ser Val Thr Val Thr Val Asp Arg 1 5 10 15 Glu Leu Val Asn Arg Ala Arg Asp Ala Gly Leu Asn Met Ser Ala Thr 20 25 30 Leu Thr Val Ala Leu Asn Ala Glu Leu Lys Lys His Ala Ala Thr Arg 35 40 45 Trp Arg Glu Glu Asn Ala Glu Ala Ile Ala Ala Leu Asn Gln Leu Ala 50 55 60 Asp Glu Thr Gly Cys Phe Ser Asp Glu Tyr Arg Ser Phe * 65 70 75 <210> 1703 <211> 105 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(313..627) <400> 1703 Met Gln Phe Thr Val Tyr Arg Ser Arg Ser Arg Asn Ala Ala Phe Pro 1 5 10 15 Phe Val Ile Asp Val Thr Ser Asp Ile Ile Gly Val Ile Asn Arg Arg 20 25 30 Ile Val Ile Pro Leu Thr Pro Ile Glu Arg Phe Ser Arg Ile Arg Pro 35 40 45 Pro Glu Arg Leu Asn Pro Ile Leu Leu Leu Val Asp Gly Lys Glu Tyr 50 55 60 Val Leu Met Thr His Glu Thr Ala Thr Val Pro Val Asn Ala Leu Gly 65 70 75 80 Thr Lys Phe Cys Asp Ala Ser Ala His Arg Thr Leu Ile Lys Gly Ala 85 90 95 Leu Asp Phe Met Leu Asp Gly Ile * 100 <210> 1704 <211> 638 <212> DNA <213> Escherichia coli O157:H7 <400> 1704 cctagcgatt ctgtcgtagt gcattgattg aaattaatcg taccgaactg ttttgttcgg 60 tatcagttaa atgtaacgct gcgagcgtta caaggtgaaa acaaatggct tcaaactgga 120 taaagctcga agttattacg ccggataagc cggaaatatt caggcttgct gagattctga 180 atattgatcc agatgccgca ttagggaaag tcattcgctt ctgggcatgg gcggatcaac 240 aaatgataga cggtaacgca gagtgtaacg ctcgcggcgt tacaaaaagt gcaatagatc 300 gcatcacttt tatggctggt tttgctgatg cgttaattca ggttggatgg ctggtcgaaa 360 ctaatggtgt gttgtcgctt cctaactttg agcgccataa cgggaaaagc tctaaaaaac 420 gggcggttac aaacgagaga gtaacaaaaa tacgagaact gaaacgaaaa ggtaacgctg 480 ccagcgttac aaaaacggat caaaaagcgt taccagagga agagaaagag gaagatataa 540 atacttatct ccccctaaat ccccctcgcc aaaaacgagc gtctaaaaaa ttcgaaccgg 600 aggctatcga gctgcctgac tggttgccgg aaacactc 638 <210> 1705 <211> 610 <212> DNA <213> Escherichia coli O157:H7 <400> 1705 cgaagcgcat gtcaccctca aaggcaaaaa agcgggcacg catactgtga ccgccacgct 60 gggtaacaat aatgccagcg atgcgcaacc agtcaccttc gtggcggata aggacagcgc 120 ggttgtcgtt ctgcaaacat cgaaagcgga aatcattggg aatggcgtgg atgagacgac 180 tctgacggca acagtgaaag atccttttga taacgcagta aaagatctac aggtcacctt 240 cagtaccaac cccgcagata ctcaacttag tcagagcaaa agcaatacta acgacagtgg 300 tgtggccgaa gttaccttta agggcacggg ttttgggtgt tcatacagcc gaagccacac 360 tgcctaacgg caacaacgat acgaagatag tcaatattgc gcccgatgcc agcaacgcgc 420 aggttacgct gaacatccct gctcaacagg tggtgacgaa taacagcgac agcgtgcagc 480 tgacggcgac ggtgaaagat ccgtcgaatc atccggtggc gggaataacg gtgaacttca 540 ccatgccaca ggacgtggcg gcaaacttta ccctcgaaaa taacggtatt gccatcaccc 600 aggccaatgg 610 <210> 1706 <211> 598 <212> DNA <213> Escherichia coli O157:H7 <400> 1706 gggaatggtt tgctaatgaa tgatcctgaa ctttataatc tcccggcata atttccaggg 60 gattatttga gagaaataca caaaagtgag ttttaacaaa ggtatttatc aggccataaa 120 tgtgacctgc ttcggataaa aaagattcag tatcgaaaaa ccaatgatac tcttgctgat 180 ggttaccaac agtaattaag atgtgatttg tttttccgta atcgcaaaaa tattgccatg 240 accataaaag aaaaattctc acaaaaatat ccccatgctt ccttttgtac ttttggcgat 300 tcagccgcgt tggccgatca cctcgcaacg ttgattgcga ctggtgttaa aacagcttcc 360 tgtggttcgc tggcgggatg tattgaagac aacgcatttc cgatgattgg tgagtataag 420 attgtagaaa atagccgtgg tgagcctgta tgtgttatca gagtgattgg cctgcattta 480 ctgcgctttt ctgatgtcac cgcggagctt gcccgtaagg aaggtgaagg tgacctcagt 540 cttgaatatt ggcgtaatga acaccgtcgt tttttccagg cagaaggaag ctattcac 598 <210> 1707 <211> 587 <212> DNA <213> Escherichia coli O157:H7 <400> 1707 taagtaacaa tctgaaaatg ccgatgatgg gatttggtgt ttttcaggtt accgataaaa 60 acgtgtgcaa acagtcagtg ttgaacgcta tccgcacggg gtatcgactc atcgacactg 120 cagcggtata cggtaatgaa gatgccgtcg gtgaagccgt tcgtgaagct atatccgaag 180 gtttatgtac ccgagaagag ttatttataa cgtctaaatt gtgggtgcag gatatgttga 240 atcaggatac ggcagcagca ggtattgaag catcattaaa aaaatcggga ctagaatact 300 tcgacctcta tttattgcat caggctatgc gcgattattt cagtgcgtgg cgtgcactcg 360 aagatgccta tgaagagggc aaattaaaag cgattggggt ttccaatttc tatcctcatg 420 ttctggcgaa cttttgtgaa acggtaagag ttaaaccgat ggtcaaccag gtcgagttgc 480 atccctattt tgcccaacca gaggcgctgg caaccatgaa gtattataac gtgcagcctg 540 aagcatgggc tccgttaggt ggtggacgac ataaaccctt tgaaaat 587 <210> 1708 <211> 575 <212> DNA <213> Escherichia coli O157:H7 <400> 1708 gttgtaccat gacctctttc tgctctgccg ggtaaatgat acgggtcccg aaaataacca 60 ttccggcatg cacggggaat atcatagaag agatgagtaa agataataac cctttcatct 120 taatgcctct tatatttatg ctggccgcca tgaatatggc ggccatttta acttactgaa 180 aaaacaagat gattatttta aatatttaat cctgggcaac acgcataacc aatgaagagt 240 taactgtacc agatgcaaca ccactgtcag tcaacttcag atattttgcc ttaaacggta 300 ttgcatattg tccatcagca gttttataac tttcaatatt aaatggtgcg gaaatatcca 360 gtacgtcact gctatctccc aaatagagat agtatccaac tgtgtcatta ctactggata 420 ttgccttatc attaccaaga attttctcgt tggtgatcaa cgaaagtttt acgccatcaa 480 tagtcttcgg acaagtaatt ttcagcatac tgctggttac accaaccgcg ccatcataag 540 ttgaatattt cgctttacca tcaaatacag tggtg 575 <210> 1709 <211> 563 <212> DNA <213> Escherichia coli O157:H7 <400> 1709 aggcctgaac cgtaggtcgg ataaggcgct cgcaccgcat tcgacaccat gcgccgatgc 60 ctgatgcgac gctgatgcgt cttatcatgc ctacaggcct gaaccgtagg tcggataagg 120 cgctcgcgcc gcattcgaca ccatgcgccg atgcctgatg cgacgcaggc gcgtcttatc 180 atgcctacag gcctgaaccg taggtcggat aaggcgctcg cgccgcatcc gacaccatgc 240 gcagatgcct gatgcgacgc tgatgcgtct tatcatgcct acaggcctga accgtaggtc 300 ggataaggcg ctcgcaccgc atccgacacc gtgctcagtg cctgatgcga cgctgatgcg 360 tcttatcatg cctacaggcc tgaaccgtag gtcggataag gcgctcgcgc cgcatccgac 420 accgtgcgca gatgcctgat acgacgcagg cgcgtcttat catgcctaca ggcctgaacc 480 gtaggtcgga taaggcgctc gcgccgcatc cgacaccgtg cgtagttgcc tgatgcgacg 540 ctgacgcgtc ttatcatgcc tac 563 <210> 1710 <211> 534 <212> DNA <213> Escherichia coli O157:H7 <400> 1710 gctatactcg tcatacttca agttgcatat gctgcgactc gaattatgta gagtttaaaa 60 gggttagcag tatatgagca ccgagggata caggtattaa cctgtaatgc ttaaagtcag 120 ggagacctgt acgctggggt gccctttagt cagaagacta gcgggcatta aagaaatgaa 180 agtcaaaact attacgatgg gcaaacttca tgatatgggt tgtccgcctt atatgaggca 240 ttaagcggtt attattttcc atttaccttt acctcttgct gtgtcagttg aaggtagagt 300 tattctatcc atgaaatggc tataatctgt gaagaagatc aacaaaaaac gatcataccc 360 cagataataa atcattaatt atgaatagcg ccatactaga tgctgttttg ttacttaaat 420 gttgtaattt cgtgttttat atttgcgtta agaaattaaa cctgccaaat aataatattt 480 ggcgcaggtt taataataaa ttaatcacta tttaggcgaa tttattgaat aaaa 534 <210> 1711 <211> 522 <212> DNA <213> Escherichia coli O157:H7 <400> 1711 taactaacaa gaaaataggt cgcataagaa gatattcttt ggtgtgggcg gatggtgata 60 ttttgtcttt attgtttcaa attatattta cttaacagcg aattaaggac cgcttaatgt 120 atagccagaa tagaaatatt ttgaggattt tcttataaaa aagaaatgaa atacttaaaa 180 aaatatctta cacataattt caatttatga ataacctgcg caaaaaagac aatcttagat 240 taagtttgag attgtacttt tttgaagtta tactattaac acatcacaaa taatattaaa 300 ttaagacacg aaaatatcat ttctttttta ttattaactg ttctattagt ttgatgcttt 360 gtaaaaatac attacaactt agtctcattt cgtcagaaat taatagggaa gcagaggaaa 420 aagtgcgatg aattctgtat cgaagcgtat caactccgtg aagggttttg agtgaatttc 480 tactattgca aaaagacaaa tgcccgatgt acagcttaca tc 522 <210> 1712 <211> 508 <212> DNA <213> Escherichia coli O157:H7 <400> 1712 tggtccgttg tgcccgacca gacacgggat ctcgaccata gcttcatcat caaagttatg 60 gattgccccg ttgttaggca caatcagcaa catccgctcc tgagtgttga aggcaattgc 120 cgccgccaga tcgacgatgt atgacgcatg ttcgtcaatt tccagcttgc ccgccgctga 180 atttcctgcc gccgtaatgg cgcggcttgc atcgaaaacc tgtttctcgc gatgttccat 240 tacctcattc gcgcgagtat gttcagggtt ggaatgctga acgacataat ccgggaagag 300 ataatatttc agataggtgt tcggcaatgt atccgggtcc agtgcctgga catcccgcgc 360 ttttgcatag gtgtcgttcc agctcgcttc agtatgtgta tcttgctgcg gtggaacata 420 accgtgctta gagacatatt gccgcagctg gtgcatcagg tcgttgccct gcaaatcttc 480 aattgatgtc caccagccaa agtggttc 508 <210> 1713 <211> 503 <212> DNA <213> Escherichia coli O157:H7 <400> 1713 gatggtagtt ccttcttcgc atggaggcaa tataaacatg ctgacgaaat atgcccttgt 60 ggcagtcata gtgctgtgtt tgacggtacc gggatttacg cttctggtcg gagactcgct 120 gtgtgagttt acggtgaagg aacgtaatat tgagttcagg gctgttctcg cttacgaacc 180 gaagaagtag ccgttgtgcg gggagtaatc cccgcatatc cggttgtcag gtcaggatgg 240 taaggcacct gctttacact ttcgcccgcg gtcagtgatg gctgcgggcg atttcgtttt 300 aagagcaatg atgagttttg ccgacagaag tccgaaacag gattcactgt ataaataaac 360 agctattttg ctaaggaagg gtaagataac ggcgggtgcc tgaagctttc cggtttcagg 420 ttaactctga ggtctggaaa gatgaagccc caggagatat ttctatcaat cctggggctg 480 ccactccgag ccccaacaac tcg 503 <210> 1714 <211> 51 <212> PRT <213> Escherichia coli O157:H7 <221> CDS <222> complement(38..190) <400> 1714 Met Leu Thr Lys Tyr Ala Leu Val Ala Val Ile Val Leu Cys Leu Thr 1 5 10 15 Val Pro Gly Phe Thr Leu Leu Val Gly Asp Ser Leu Cys Glu Phe Thr 20 25 30 Val Lys Glu Arg Asn Ile Glu Phe Arg Ala Val Leu Ala Tyr Glu Pro 35 40 45 Lys Lys * 50 <210> 1715 <211> 498 <212> DNA <213> Escherichia coli O157:H7 <400> 1715 tcgccccgac aatagcgcat aataatgcgg caatcagaca gtaattaaat agccgtaagg 60 cacttactgg ctcatattta tttttcccca aacgcttatc ccgcacgacc agtaaggcga 120 cggtaacaat aaacatcata ttggagaaat tgatagccag tgaaaccagt ccccattcgg 180 tggttatggc atcataaacc agcatcgcca cataactgat cgcatagtaa tgcagtcgat 240 taagccagac atagcgggca aacacccccg ccattacgcc attcagcggc cagaaaagag 300 aaagttcgtg aaccagccgt aactctgcac caataaaata gaacagcgtg gttagcgcaa 360 aaatagcgat gctattacgt agcagatgac cttcctggaa cacacggaaa gttgaaatgg 420 ggtgtacatg cattaattat ctgtccatac aattgcgggt ggcaattatc tcaacgtaat 480 aagtaaattc tcataaag 498 <210> 1716 <211> 463 <212> DNA <213> Escherichia coli O157:H7 <400> 1716 ccgcgagact gccgccgcca gacaaacgct gctggaaaaa ggcagtgtac ttattcgtgc 60 tctcgaatcc ggctcgcgcg tcggcatggg gatgcgcatg catcatgcgc agcagcaggc 120 cttactggaa gaaatggccg ggcagcctgg agtacgttgg tttgcggtca cggatgaaca 180 aggaacaatc gtgatgcata gcaactccgg catggtggga aaacagcttt attccccgca 240 ggaaatgcag cagttacatc cgggagatga agaagtgtgg cggcggatcg atagcgcaga 300 cggcgagcct gttctggaaa tttatcgcca gtttcaaccg atgtttgctg ctggaatgca 360 ccggatgcgc catatgcagc agtatgccgc gacaccacaa gcaattttca tcgctttcga 420 cgccagtaat attgtgagtg ccgaagatcg tgagcagaga aac 463 <210> 1717 <211> 459 <212> DNA <213> Escherichia coli O157:H7 <400> 1717 tgaagaaatt atgcgtggca gtctcctttc ggtccataat agcagaacaa aagaaagagc 60 caaaaatgac ggtcagatat tatatcagtt ctgctgattt aaccgcaggg aagttcgcca 120 cagcaatccg aaaccactgg cacgtggaga ataagctgca ctggcgtctg gacgtggtaa 180 tgaatgaaga cgactgcaaa ataagaagag gaaatgcagc agaattattt tcagggatac 240 ggcacattgc tattaatatt ttgacgaatg ataaggtatt caaggcaggg ttaagacgta 300 agatgcgaaa agcagccatg gacagaaact atctggcgtc agtccttgcg gggagcgggc 360 tttcgtaatc ttgccctggt attcgctgct ttgatgatga tgtaaaatga ttgtttttga 420 actggatata acagcttggt agggaagaaa gcataaccc 459 <210> 1718 <211> 412 <212> DNA <213> Escherichia coli O157:H7 <400> 1718 cagcgtagca acctatcgta acaatggttt ctttggtcaa gttgatggtc tgaactttgc 60 actccagtat cagggtaaca acgagaaaag cggattattt gatcaagaag gttcaggtaa 120 cggtaatgga cgtaaacttg ctaaagagaa cggcgacggt tcagtatgtc cacttcctat 180 gactttgact ttggtttaag tctgggcgct gcttactcta actctgaccg taccgacaat 240 caggttcaca aaggtactca taacactcgt tatggagatc gcttcgatgc aactgctggc 300 ggtgaaacag cagaagcatg gaccgttggt gctaaatacg acgctaataa cgtttactta 360 gcagctatgt atgctgaacc ccgtaacatg actggttacg gtgatgctga tg 412 <210> 1719 <211> 404 <212> DNA <213> Escherichia coli O157:H7 <400> 1719 taagattgat ttttcttctc aagttccttg ttcttctgcc gatattacct cgtacagtga 60 cgaggactga acaatggcca ctatctcttc aacttcaatt ccttccatac aaacacagag 120 tagtaacagg gcatcacaag gtagcgatgt tgcttcacaa atcgcgcgga taagtcagca 180 aatcatcaaa ctcactcaac acattaaaga gattgtagac actagcggca gtgctgaaga 240 caagcaaaaa caggccgaat tgattcaaca gcaaatcacc ctactggaaa cacaactggc 300 gcagttgcag agacagcagg cagaaaaggc gcaggagaaa gagcagcgtt tgtctctgaa 360 tgtatccctt ctaaatcctg ttgaaaatac gactcatatc ggta 404 <210> 1720 <211> 399 <212> DNA <213> Escherichia coli O157:H7 <400> 1720 atcagatatg acatataagt tgtcaggtca ggaactagat attttgtgta cttgatttgc 60 aaacagctcc ggtgttggtg gcgtcaaaat cgctgaagcg ttccccgaag gccggggcag 120 cccacatgga tgtgggctga gggcgcgtct tacaaggacg tttcctcgcg cccgacccgg 180 tagccgaagg ggataagctg aaggtaccgc gcagcggcga ttttgttcgc cagagcccgg 240 gggtgcaggg ggaggaggcg attgtcctcc ccctgcgcgc tccttgcgcc agtggcaata 300 tgtggcttag ctcatgaaag gagcgcaaca agatgatgaa gctgaataag cgattcattg 360 tttctgataa actgcgattc cactattatc gcagcttac 399 <210> 1721 <211> 393 <212> DNA <213> Escherichia coli O157:H7 <400> 1721 ctctctttaa ataaccacaa cgcattgatc tacctttaaa tcttttcttc gagcgcactc 60 gtaaaacgtc atgtaaggca gacatacatt gcaggaataa gggattaatt acggcagtaa 120 acgtgggcga tgaagtggct atcaaaaagt tcggttcagg gcgatgcacc ccgcatcgcc 180 ctgattgaca tcgttgattc tttgacctaa tttagtgagt aagggtaagg gaggatgact 240 cctcccctga gactgactgt taataagctc cgaaacttat cagtaacagt acaatcagta 300 tgatgacaag tcgcatcata acccttctcc tttaagccct cgcttcggtg agggcttcac 360 cgttacagcc ccatgctgtc ccgccatcgt aaa 393 <210> 1722 <211> 391 <212> DNA <213> Escherichia coli O157:H7 <400> 1722 ttttcagcta tgaacatccc tggctcaaaa agccggggat tttttatatc tgcgttccgc 60 taaaaggtgc aaatgatcag gctgttgcag cgttttgcgt gattgctcgg ggaaggcaaa 120 actgcttcag ggaaagcgtt gcgcggggtc cggcgctcat caacaatcgg ggagtaagca 180 aagggctgaa acgggaaagc ccctcccgag gaaggggcct tacagaagga aagggttatg 240 atgaagctcg tcatcatact gattgtgttg ttactcgtaa gtttcgcagc ttattaacag 300 ccaatcagag gggggagaaa tcctccctca cccttgttcc tttactttag gttgaaaaaa 360 aatcagcgtc aagaaggttt cattaacaca t 391 <210> 1723 <211> 372 <212> DNA <213> Escherichia coli O157:H7 <400> 1723 ggagatctat gacttactga cgccaacgat caacctgcaa attcactgta cccgttatcc 60 catgcgcagc caaaatggtg gaagcaccga tttaccgcgt tattggatca cgttggataa 120 aaacgtgatc tgggattacc cgaaagactt tattgcaggc aacggtggag tgcgtaattt 180 tcacggtgaa acttgctggt atccttacct gacggatatt tgttcaattt ctgatttatt 240 gcgtgaatat attgacaccc caaaagcgga gttgttaaca aaacaattta ccagcgataa 300 atgggggtta gtgaatattc tgcgtgctgc tgacaggcga atagggatga ggcgattaga 360 tcagttacgg cg 372 <210> 1724 <211> 352 <212> DNA <213> Escherichia coli O157:H7 <400> 1724 cagaggggga tttttaattc tatatgagtg tttagcattg ttgcgctcct ttcatgtgca 60 atgccatata aagccactgg cgcagggagc gcgcaggggg cggccagtcg ccgccgcccc 120 ctgcaccccc gggctctggc gaacaaaatc gccgctgcgc ggtaccttca gcttatcccc 180 ttcggcaacc gggtcgggcg cgaggtaacg tcctgtaaga cgcgccctca gcccacatcc 240 atgtgggctg ccccggcctt cggggaacgc ttcagcgatt ttgacgccac caatacccgt 300 gcggtttgta atgtcgaaga taaaacaacc agggcagata aaatgccaat gc 352 <210> 1725 <211> 349 <212> DNA <213> Escherichia coli O157:H7 <400> 1725 cagggaattt ggcattcacg ttgacctgaa agagattttt acccgtttta aaggcgtaaa 60 actctacgaa atcatcgata tcatcagtaa agaacagggc gtgacgatgg tccaggccga 120 tgccgagcac gtttaccgcg cagaagtagc acgtctgttt gataccgaac ttgaggacat 180 cgcaggagcg aacgaattgc tggcgagcat taacgtgccg atgtgcgtcg tctctaacgg 240 tccggtcagc aaaatgcagc attcgcttgg taagctcaac atgctgcact acttcccgga 300 aaaactgttc agcggatatg acattcagcg ttggaagccc gatccggca 349 <210> 1726 <211> 341 <212> DNA <213> Escherichia coli O157:H7 <400> 1726 aggagaacct gccagactgt tatcgtgatt ttgtcgacgt aaagcgataa aaaagattcg 60 gttcgccaac gatatagatg ttgccgctat catccatcgc tatcccttcc gcctgcttga 120 tgttgtgtga aaggccatac ttacctttgg ttaacgacat ttcgccgatc acgtcacctc 180 tcacggtcac ttcctgcagg gcgcgtgact catgtgacaa caccagcaac gtatttttct 240 gtgggttaaa ttccgcgcca gaaacatcgt ctaaagtaaa ctgacgctgc aacgttttat 300 ctttgctgat atgcaactca tcgctacgca atagcccggt t 341 <210> 1727 <211> 325 <212> DNA <213> Escherichia coli O157:H7 <400> 1727 aattggctga taccgatact ggcgcttccg ttggcatcac ctgctgggtc tgctcctgga 60 tcaccggctt aatttcatga ggcatcgaag gagatatcgc ccctgtttgc tggcatggta 120 ataacaggcc attgaacaga tcggctggca gcgggtcagg cagatgaata tcgcagtggg 180 ccacaccgcc ccatgaaacg atcatatgct cgccaggttt tacgcccgcg aggtagacgt 240 tgccgtcatc gtcaaccaga ccgacgttct gcgcgctgtc gtttttcact tccgcgccaa 300 acggcggata actgccatct tgcag 325 <210> 1728 <211> 322 <212> DNA <213> Escherichia coli O157:H7 <400> 1728 ttcatcatga ccctttcctt atttaaggcc ccttcctcgg gaggggcttt cccgtttcag 60 cgtcccgctg aaatcgtcgg cttacctcct ttcgccctga attcagtcta tcgctgactt 120 gcggataaaa tagtttcctc tgtgattatt gcgtaacgtc tcgcaaagaa tatttgctgg 180 caggatcgca gactgcaaag cctgcggatt gacattctga acgtgaaggc atactttcag 240 gagtgagggt agagcggggt ttcccccgcc ctggtagtct tagtatgctg ggtagctaat 300 cactaagagc accacgatga tg 322 <210> 1729 <211> 297 <212> DNA <213> Escherichia coli O157:H7 <400> 1729 ttttgataac gtggttaaaa atctttcagt agtcttccgc acctcccccg cagacacgca 60 actgagtctg aacgcgcgta atactaatga gaacggtatt gccgaagtta cccttaaggg 120 cacggttttg ggtgttcata cagccgaagc catactgctt aacggcaaca gagatacgaa 180 aatcgtcaat attgcgcccg atgccagcaa cgcgcaggtc accctgaaca tccctgcaca 240 acaggtggtg acgaataaca gtgacagcgt gcagctgacg gcgacggtga aagaccc 297 <210> 1730 <211> 287 <212> DNA <213> Escherichia coli O157:H7 <400> 1730 ttcagccgtc atccaggaag ggcatatcag caactctggt ggacaaccat aaatttctgc 60 cattttgctt ttgatgtttg agctaagccg ttccgtcttt tcgatctgtt ttagagaatt 120 aatcgagata cctaacattt tacttacttc agcaagcgat aatttatgcc tgatacgcac 180 ggcggctagc caggaaatac gctggctgaa cattaaattg ataatctccc gttcctggtt 240 ttccagatcg atcatatttc cttccttgga tattttaatc agcgagt 287 <210> 1731 <211> 236 <212> DNA <213> Escherichia coli O157:H7 <400> 1731 accttgatca aatgaatttc gaatataata aaggaaatct tttgagatat ttatcacgaa 60 taaagctatt tatgttacca atatcatttc gagtacgcac actatctatc tgttttttaa 120 ggatataaaa aacaacatgt aagttatgta aattgccgat gctactaagt aacattatag 180 taaaaaaagt aaaaatgagc gatttttgat agaataaagc atgagaaaag gtgata 236 <210> 1732 <211> 233 <212> DNA <213> Escherichia coli O157:H7 <400> 1732 ttgcgtttgt cgttattacc cacagctacc acttctgtcg taacgccttt tgcagtagaa 60 gaagcacgat agttggtttc aactcgttgt aacaactgcc cacaacgttg ctgaagatga 120 ttattaacaa catccatact gcatgtaggg gaactaattc tgccattgat ggttaatgtt 180 gtagtatcag aagagaacgc gggtgatgct agtccataag caagaaaaac agc 233 <210> 1733 <211> 227 <212> DNA <213> Escherichia coli O157:H7 <400> 1733 agctaagtat gtcccttata tttactcctg ctcaggctat ctcactcgcc agcccgaatc 60 ccggcagtgc tcgcaatcct cacgtactta agtacgctcc ggttgctgtg cgctggcggt 120 atccggtctg acttcgccga tgacgcctgt acttcaggaa cagttaccta aaatttattc 180 ttagttcaca gacccggcgc aacgccgggt atattcactc agccaac 227 <210> 1734 <211> 226 <212> DNA <213> Escherichia coli O157:H7 <400> 1734 gtgatgcttc gtgccattgc cgctattgaa atcattaatg ttataaaaat aatgcggctc 60 aaaggtatat gagaacttat cggtaataat aaagttccag tagttgccaa tctcgtagct 120 gtcattatta tccagatcac cgtttaaatc ggttgagctg tagttattat ggttaaaacg 180 gttgcgcact gtcaggttaa accacggagt aaatttgtag ttaaca 226 <210> 1735 <211> 225 <212> DNA <213> Escherichia coli O157:H7 <400> 1735 aatcaattcg ttaaacacga catacaactc attaccctgc aaataattac aactggcaaa 60 agccagagac gggcttttat gcccaggaga tgactcatga tgagcaatgt taagaaaaaa 120 gatgtgccgc tgataagcat cagcctggtg gccattcttt tcatcgcagc tgcattaagc 180 cttttcccac aacaatcggc cgacgcggcc aacgcaatat acact 225 <210> 1736 <211> 225 <212> DNA <213> Escherichia coli O157:H7 <400> 1736 cattagccac cccattatta gaagttgtga caatgcgaag gtggcggaat tggtagacgc 60 gctagcttca ggtgttagtg tccttacgga cgtgggggtt caagtccccc ccctcgcacc 120 acgactttaa agaattgaac taaaaattca aaaagcagta tttcggcgag tagcgcactt 180 ggtagcgcaa ctggtttggg accagtgggt cggaggttcg aatcc 225 <210> 1737 <211> 222 <212> DNA <213> Escherichia coli O157:H7 <400> 1737 agcgcgccag ccaaacgcca gacgcaaact ctgaccttta tcccgtggtt tagctgggcc 60 aaccggggtg aaggcgaaat gcggatctgg gtgaatgagg aaaagcattg ccatccgtag 120 gttggataag gcactcgcgc cgcatccaac gtaaggagca cattgcctga tgcgacgctt 180 aacacgtctt atcaggcata caagtcggtg cgagagcgta gg 222 <210> 1738 <211> 221 <212> DNA <213> Escherichia coli O157:H7 <400> 1738 agctgccctt ttatactcaa acaacaaaag gacagtgcaa tgacaacaca atcccaccat 60 gaccacgtag aaaagcagtt tagctctcaa gccagcgaat atctgaccag taccgtacat 120 gcatccggac gagatttaca gctcctggcg gtgtgtctgg ctgattatcc tgatgcaagt 180 gtacttgata tgggctgcgg agcagggcat gccagctttg t 221 <210> 1739 <211> 217 <212> DNA <213> Escherichia coli O157:H7 <400> 1739 aatacggcat tatggcactg aagggcaaga attttggtca gctagagaat tggcaccgtt 60 actggattat cgggactggc gcaattttca aaaggtactg gcccgcgcga ctcaagcgtg 120 cgaagccagc aatcaagctg catctgacca tttcgttgaa accaccaaaa tggttgtatt 180 aggttcaggg gctcaacgag aacttgaaga tgttcat 217 <210> 1740 <211> 213 <212> DNA <213> Escherichia coli O157:H7 <400> 1740 ttgcgtgctt ctccatgttc gaagacacca gaaatacgtg aaagatattc tgctggtata 60 cgttcttcat tttccgttgc aataaaaaca ggaatgtcat agccagtagc gtctatttca 120 tcgagttttc cacgttcaac atcactgact gataaaataa tggcggcaac gtcaatataa 180 ttactttcgt ctatattcac gcatgcacga tga 213 <210> 1741 <211> 210 <212> DNA <213> Escherichia coli O157:H7 <400> 1741 atcgaaactg ttagcaaata taccattgcc tgatgcgctc cgcttattag tcctacaaaa 60 catcaatata ttgaatttag gcaacatttg tagaccagat aaggcattca cgccgcatcc 120 ggcaggaaca aagcccactt tagttacaga acacaatgtt cttgagggtt ttaatgacat 180 attttcacga ttactttttt aacctagtca 210 <210> 1742 <211> 203 <212> DNA <213> Escherichia coli O157:H7 <400> 1742 tactcgtcat acttcaaatt gcatgtgctg cgtctgcgtt cgctaacccc agtcacttac 60 ttatgtaagc tcctggggat taatgagaga catccatgtc tctcaccgaa ggccagcctg 120 cggctgggca aattcgttcc tgacgaattt gtcactcgct tgccgccttc ctgcaacttg 180 caacttgaat tatttagagt ata 203 <210> 1743 <211> 200 <212> DNA <213> Escherichia coli O157:H7 <400> 1743 tcgccaccgg cggatgctgc gtgaacgcct tatccgccct acatgttcgt tcccgtaggc 60 tggataagac gcgacaagcg tcgcatccgg catctgcacc tcgccactgg cggatgcggc 120 gtgaacgcct tatccgccct acatgttcgt tcccgtaggc tggataagac ccgacaagcg 180 tcgcatccgg cgtctgcacc 200 <210> 1744 <211> 194 <212> DNA <213> Escherichia coli O157:H7 <400> 1744 gtaggtcgga taaggcgctc acgccgcatc cgacaataac agcattgcct gatgcgacgc 60 tgccgcgtct tatcaggcct acgagttcgg tgctgtgtag gtcggataag gcgttcatgc 120 cgcatccgac aataacagca ttgcctgatg cgacgcttgc gcgtcttatc aggcctacga 180 gttcagtgct gtgt 194 <210> 1745 <211> 187 <212> DNA <213> Escherichia coli O157:H7 <400> 1745 tcgcatggcg aataaacctg agttagctct cgactgatca tatgaaatcc tgcaactcat 60 cgtctctccg gcgatgagtt gtcaggaagt aatgcgtatg gatgatactc tccagggccg 120 gtgataactg aagatgatgt taagctgcta aatgagccac gttgacatca tttggcagct 180 tcatgca 187 <210> 1746 <211> 186 <212> DNA <213> Escherichia coli O157:H7 <400> 1746 gatataaata atgctgaatt tactgatggt ggtattgatg atcgtagtga tattggcatt 60 gactccaatg atacagacga tattgatatt gataatcaag aaccaataaa atcacccgcg 120 aacgatgaaa acaaaaaagt cggccaaacc atcatcaatg aaaacatagt agagaatact 180 catgat 186 <210> 1747 <211> 182 <212> DNA <213> Escherichia coli O157:H7 <400> 1747 tcttatccga cctacggttc tacccctgcg taggcctgat aagacgcacc agcgtcgcat 60 caggcaacgc ctgtcggatg cggcgtgaat gccttatccg acctacggtt ctacccctgc 120 gtaggcctga taagacgcgc cagcgtcgca tcaggcaacg gctgtcggat gcggcgtaaa 180 cg 182 <210> 1748 <211> 180 <212> DNA <213> Escherichia coli O157:H7 <400> 1748 gtcaatttgg ttgaactgtc aaaaattgaa ttacttaaag ttcattgctt attgataaat 60 tatttgtctg atttgttgtt ttggtatttt taggatctat aattcaaaat taatgatttc 120 attaacgtgt tgaaatgcag tgtttttgtc aacttattct ttgtgcgtat agatattttt 180 <210> 1749 <211> 167 <212> DNA <213> Escherichia coli O157:H7 <400> 1749 gccagcgaca aatgtacatg gtgattctgc aatattacct ttaatggtta aagttccggt 60 atctacttca gcagcgaaaa taccagcact cataaataca gaagataaga cagcgacagc 120 aataattgaa tgtttcatga tgcattcctt aataagttta ttttgtt 167 <210> 1750 <211> 166 <212> DNA <213> Escherichia coli O157:H7 <400> 1750 tgccaataac gaaaccgatt ttaatgtact tatcaaaaag cggtcacgtt aatcttttca 60 tcaatgtcga tttcttcgta aaggctcgcg ttttttatgt cagagattgc aagttgcttg 120 tacaggtcaa cgaaattgat ccataatcat tttcgttgga atcgtg 166 <210> 1751 <211> 160 <212> DNA <213> Escherichia coli O157:H7 <400> 1751 aagttaaata atatacagga gttaaataat tcgcaggagt taaataattc gcaggagtta 60 aataattcgc aggagttaaa taactcgcag gacttaaaaa attcgcaggt gagttgtaaa 120 ggttcagttg attttacgat tacggattta ttagaaaaat 160 <210> 1752 <211> 149 <212> DNA <213> Escherichia coli O157:H7 <400> 1752 tacacaaaca aacgtacatg attgctcccg ttcaaattct gcgcaaagtg taaatgagaa 60 tagttatgat tacaatagca cagttttatt tgcgccatag ttcagcgagc aaaattacga 120 ctaaatattt cgagctcaaa ttacgggca 149 <210> 1753 <211> 148 <212> DNA <213> Escherichia coli O157:H7 <400> 1753 gcgttccccg cgatggctgg aatcatcaag cacttgcagg aacagtgcct cgctaatctc 60 ttcaccataa aatgcgctac tgaatccgtg cgaactgcgc agattagccg gtaaatcacc 120 agcgttagat agcggctgac ggtcgatg 148 <210> 1754 <211> 148 <212> DNA <213> Escherichia coli O157:H7 <400> 1754 gtcaccattg caataatgcg tatcgcttag aaaccattgc cttaaccagg aaagccggag 60 taaatggaca gttctcagta cgaaaaataa gaaatgacca atctgccgac gcttgttaat 120 ggttatatcc tggcgtcggc agatcgcc 148 <210> 1755 <211> 143 <212> DNA <213> Escherichia coli O157:H7 <400> 1755 caaataattc gctataacaa acatttttga aactgattaa ttaccgtaaa ttaccgtaaa 60 taacatttat gggatgaata aaaaagccaa aatcattcat aggaatgatt ttggcttttt 120 aaatatgctt aaaacggtgt tgg 143 <210> 1756 <211> 139 <212> DNA <213> Escherichia coli O157:H7 <400> 1756 gtttcagagt ctgcgtgatg ccggatgcgg cgtgaacgcc ttatcccgcc tacacaaaat 60 ggcattggct cgtaggcctg ataagacgcg taagcgtcgc atcaggcgat cagcatcagg 120 caatcgattc aggtgcctg 139 <210> 1757 <211> 138 <212> DNA <213> Escherichia coli O157:H7 <400> 1757 gcaagtaagt aaagtctggt gatcaagtga ggtggtgtag cgcgcctgtt cccgctgcgg 60 cgtcgcgcac tccactcctt gctcataata cggcgggttg ctgatgatta aatcaaagcg 120 cgcggtctgc tgtgttac 138 <210> 1758 <211> 133 <212> DNA <213> Escherichia coli O157:H7 <400> 1758 gttggtagaa gacgcgttac cggtgaaggt agtggtcatc gttgtctggg tgtcaaacac 60 acagtcttgc agatggatct ggaaagcttt cggtgtagaa gtcccgttat ttttcaggat 120 ccctgaacca atg 133 <210> 1759 <211> 133 <212> DNA <213> Escherichia coli O157:H7 <400> 1759 tctgtcccag cgccgcctcc tcagaaaaga gtcggcgctg aaattctcct ttcgttctgg 60 aaagcgcctc gcataatctg aagaaaacca atgtaatacg cacatctgga ttgttaccgg 120 cagatgcccg gcg 133 <210> 1760 <211> 129 <212> DNA <213> Escherichia coli O157:H7 <400> 1760 ttccatggga tggattagca catttatctt cgttttgcga attacatgac agtccgaaac 60 aagatgaaaa agtatttaaa aaagggggga ggaagaatga gtaggacgaa ttattctgaa 120 ccagaaagc 129 <210> 1761 <211> 128 <212> DNA <213> Escherichia coli O157:H7 <400> 1761 tacttaaata tattgtgaaa tactttcata aataacccgt gatatttttg acttgttagt 60 aacaaaataa atgatacatg tctgaaagac atattttttg acgatataaa gcaatgatgc 120 gtatatac 128 <210> 1762 <211> 126 <212> DNA <213> Escherichia coli O157:H7 <400> 1762 atccttccag accatgggcg ggttgagggc aattattcgc attagcgcag gcctgttccc 60 ctcaccctaa ccctctcccc gaaggggcga ggggaccgtc cgtgcactta tctggcttag 120 ccctca １２
６ ＜２１０＞ １７６３ ＜２１１＞ １２４ ＜２１２＞ ＤＮＡ ＜２１３＞ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ Ｏ１５７：Ｈ７ <400> 1763 aagctgcctg aagtgttgat ggaaagaggg cgtgctcatt tgcacgcggt ttgccagctt 60 gagtcttcaa cgctgggaag atgcggcaaa cggcaaatcg gcataccagc cagcctatat 120 ccgt 124 <210> 1764 <211> 119 <212> DNA <213> Escherichia coli O157:H7 <400> 1764 ttagccgatg tgcctgatgc gctacgctca tcaggcctgg cactctttta atatattgag 60 ctcgcaatat tttatattac gcctcagccg aaacacacaa agcgcacttt attaacaat 119 <210> 1765 <211> 115 <212> DNA <213> Escherichia coli O157:H7 <400> 1765 aaagcgaaag gccatcctga cggatggcct ttttgcgttg gtgcaaaaaa atgccggatg 60 cgacgctggc gcgttttatc cagcttacgc aggcacgata gggggcagct tattc 115 <210> 1766 <211> 113 <212> DNA <213> Escherichia coli O157:H7 <400> 1766 actcgccagt cttgaaagct cccggtcaag tctccattca aaggagtggt taaaggtcgt 60 tgctactgat aatacggcgg taaaaaaact cgaacgatac tggggcctgg acg 113 <210> 1767 <211> 112 <212> DNA <213> Escherichia coli O157:H7 <400> 1767 ccttggaaga gaatgggtag cacgtatcac cccatcactc acagcggctg ttcgcgcccc 60 ggaaattgcc cgtagtggcg ttttgttctc attacagatg cacctgagtc tg 112 <210> 1768 <211> 105 <212> DNA <213> Escherichia coli O157:H7 <400> 1768 agcacattgt tgattttcaa taaagaaatc aatcaaataa aatcattagc aaccatattc 60 tttcactgtt gctctgcgat tccttcctgc acgtacagca gaaat 105 <210> 1769 <211> 104 <212> DNA <213> Escherichia coli O157:H7 <400> 1769 gtttgttcat ttcttttaga ccattcaact aattgctcaa tctcaccttt attcgctgat 60 ttatgaactt cagaagccac attttccttg atctccggtt ttaa 104 <210> 1770 <211> 103 <212> DNA <213> Escherichia coli O157:H7 <400> 1770 accgatgcct gccgcgcttg gaaatctgtg cccgaaccgt aggccagata aggcgttcac 60 gccgcatctg gcgtctggag caaatgcctg atgcgacgct tgt 103 <210> 1771 <211> 102 <212> DNA <213> Escherichia coli O157:H7 <400> 1771 ttactggagc agcgcagcag tgaactggaa gcgcgcaata attcggtagc agatcttcaa 60 tctcctccgg ctatcccgcc tattgataaa gcagaataaa gc 102 <210> 1772 <211> 100 <212> DNA <213> Escherichia coli O157:H7 <400> 1772 agtcattctg cgttggaata ttcaacgggg agtggtcgtt attccgaaat cgacacatca 60 acagcgtatc gaagaaaatt ttgctatctg ggatttctca 100 <210> 1773 <211> 100 <212> DNA <213> Escherichia coli O157:H7 <400> 1773 ctacagtcca catcaagatc gtgtccggtt atgcagcaac aatactgtcg atggctgctt 60 tcgcgtcaga ctgcgctttc gctgccattt ccggaccgta 100 <210> 1774 <211> 99 <212> DNA <213> Escherichia coli O157:H7 <400> 1774 ggttcgctat ctctggtata tgcctgataa gacgcgaata gcgtcgcatc aggcacactg 60 ccaatgtcgg atgcggtgcg agcgaccaat ccgacttac 99 <210> 1775 <211> 99 <212> DNA <213> Escherichia coli O157:H7 <400> 1775 cagaaggttg ccgctatgaa gccaacgatg ctactcatga ttaccgtatt cctgattttt 60 ccagcccttt ctcaggccga gtcgccattc agttctcta 99 <210> 1776 <211> 96 <212> DNA <213> Escherichia coli O157:H7 <400> 1776 tggaacagca acaggcaaat gcggaaccag aacaacaggt cgatccgcgc aaagctgccg 60 tcgaagccgc tattgcccgt gccaaagcac gcaagc 96 <210> 1777 <211> 95 <212> DNA <213> Escherichia coli O157:H7 <400> 1777 cagattcggg ttcatgttca gaatgttgat taacaggctg cttcttctga tgttggaatg 60 tgcatatcaa aatcaggaaa tgacaagttt atata 95 <210> 1778 <211> 94 <212> DNA <213> Escherichia coli O157:H7 <400> 1778 tgagcatcat caccacgatc acgaacatca tcaagaccac gaccacgacc acgaccacga 60 acatcatcac catcatgaac atggcgacaa cgaa 94 <210> 1779 <211> 93 <212> DNA <213> Escherichia coli O157:H7 <400> 1779 aagtggcgca agaatttgta ggcctgataa gcgtagcgca tcaggcattt atcaccattg 60 ccggatgcgg cgtgaacgcc ttatccggcc tac 93 <210> 1780 <211> 93 <212> DNA <213> Escherichia coli O157:H7 <400> 1780 attcttgacc ctgatgacat actccgcgct tgctgcgtaa acaactttac gtcggaggaa 60 taagacgcaa agtgtggcat tcggcatctc ata 93 <210> 1781 <211> 92 <212> DNA <213> Escherichia coli O157:H7 <400> 1781 ttgcaataaa agcgagcgga ctgttccctc gcccctttgg ggagagggtt agggtgaggg 60 gaaattcgca ccgccgcgtg cttctgctct gc 92 <210> 1782 <211> 92 <212> DNA <213> Escherichia coli O157:H7 <400> 1782 aaatttggct ggaagaaaaa aactatcact gcataaaata atttgacgcc gggatgtttc 60 tgtatttccc ggcatcttta tagcgatatc aa 92 <210> 1783 <211> 90 <212> DNA <213> Escherichia coli O157:H7 <400> 1783 gctgcgcact cttcaccgct aaattcagca gattgcgaga cgccttccaa agagatttaa 60 gtgccgggcg acaggcaccc ggcaaagaga 90 <210> 1784 <211> 88 <212> DNA <213> Escherichia coli O157:H7 <400> 1784 ctgccgcgtc ttatcaggcc tacaaaaccg aaccgtaggt cggataaggc gttcacgccg 60 catccgacaa tcagcgcctg atgcgacg 88 <210> 1785 <211> 87 <212> DNA <213> Escherichia coli O157:H7 <400> 1785 cgtgagcacc tcagccgaca tgtggcagct gttgtaggtc tgataagacg cgctagcgtc 60 gcatcagacg ttgattgccg gatgcgg 87 <210> 1786 <211> 83 <212> DNA <213> Escherichia coli O157:H7 <400> 1786 tgaccgtgtg ccggataaag cgtttacgcc gcatccggca cagtcagcat taccgactta 60 gtttattttt gtcagcgcat aat 83 <210> 1787 <211> 81 <212> DNA <213> Escherichia coli O157:H7 <400> 1787 agaagatgag attgccgaag tgttgcttaa taacacgtat gcggtgttta acgttcgtgg 60 gtagtttgcc cttcgtaggc a 81 <210> 1788 <211> 80 <212> DNA <213> Escherichia coli O157:H7 <400> 1788 caggtacagc cgagcctgca atgaagctgg tgtttaatgc caatggcgtt ctgacctcaa 60 atccaacaga gaatattacc 80 <210> 1789 <211> 80 <212> DNA <213> Escherichia coli O157:H7 <400> 1789 ctactgtcgc actaaccagg aaggcccgat aagcgttgcg catcgggcaa tctggggttt 60 gctatcagtt ctgattccct 80 <210> 1790 <211> 78 <212> DNA <213> Escherichia coli O157:H7 <400> 1790 gtttattcat taacatattt gtaacttttt tatcattgtc ttttcctctt ttgatgaaat 60 ggcaacgata gaggcgag 78 <210> 1791 <211> 78 <212> DNA <213> Escherichia coli O157:H7 <400> 1791 agagattgcg aaaagtctga agcgattgaa ttaagataat atagaaaatc agatacagca 60 aaaatggcag attgatga 78 <210> 1792 <211> 76 <212> DNA <213> Escherichia coli O157:H7 <400> 1792 tcgccacgcc agcagtgatt atctgctggc ttttttcttt ttggcgattg agtatcggac 60 ggtgtacaaa ctaacg 76 <210> 1793 <211> 75 <212> DNA <213> Escherichia coli O157:H7 <400> 1793 gatcgcacgt aatcacgtta ttcggggact ttatctgcgg gatattaccc ttcaggtaag 60 tccttttctc gccag 75 <210> 1794 <211> 75 <212> DNA <213> Escherichia coli O157:H7 <400> 1794 gatttctgga gaaaatgcaa tcagcagtta ataactctgt cgcataaggt catttagcga 60 ccaggaaatc ccggc 75 <210> 1795 <211> 75 <212> DNA <213> Escherichia coli O157:H7 <400> 1795 agcctggtac ggcagcgacc cgatgaaagt atataaatcc tctttcacca acatgtatag 60 caaactgtcc cttct 75 <210> 1796 <211> 73 <212> DNA <213> Escherichia coli O157:H7 <400> 1796 cgtttacaac tctctttata tattcagcag ataaaaatat aactcattaa caaaaatcat 60 ttgtttttgc ccc 73 <210> 1797 <211> 70 <212> DNA <213> Escherichia coli O157:H7 <400> 1797 tcttttatgc ctggctgtgt caagataata aacagagtaa ttattcaaac atgagagtat 60 tattcttaat 70 <210> 1798 <211> 70 <212> DNA <213> Escherichia coli O157:H7 <400> 1798 aatgagcaaa attcttcgaa atggcttatc cacaagtaac tctttttgtt gagattatcc 60 gattaaggtg 70 <210> 1799 <211> 62 <212> DNA <213> Escherichia coli O157:H7 <400> 1799 actcgctggc aagaactctg ccgtctggca gcaccaggag tggtgtaatg accacgcgcc 60 tg 62 <210> 1800 <211> 60 <212> DNA <213> Escherichia coli O157:H7 <400> 1800 agtgcatggc tttatgggta ttatgagata aaacaatcac ctgggcttcg ctatcctttt 60 <210> 1801 <211> 58 <212> DNA <213> Escherichia coli O157:H7 <400> 1801 agggttatat tatggggcga tggatactca tgccacgccc caaaataacg gaattgaa 58 <210> 1802 <211> 56 <212> DNA <213> Escherichia coli O157:H7 <400> 1802 agagacagtg gttgcacaat caatcgcctt tgtacagttt cggactaaga tccact 56 <210> 1803 <211> 53 <212> DNA <213> Escherichia coli O157:H7 <400> 1803 caagccgcag cagatctgct ttcgggcagg tctgctcatc cacctcaggc aat 53 <210> 1804 <211> 53 <212> DNA <213> Escherichia coli O157:H7 <400> 1804 ctccgcaacc ccatgttttc acataactgt tgcgttgacc aattgaatct aca 53 <210> 1805 <211> 50 <212> DNA <213> Escherichia coli O157:H7 <400> 1805 tggcgtaacg cactcaccag tagcagtata taaagtgggt ttcatggtaa 50 <210> 1806 <211> 49 <212> DNA <213> Escherichia coli O157:H7 <400> 1806 tgtcggcggc catgtttgcg catggccgcc atacccgtct tagcttttc 49 <210> 1807 <211> 49 <212> DNA <213> Escherichia coli O157:H7 <400> 1807 agccaatagt gaagcaagaa aattgttgtc tgctttcgcg cagcacaat 49 <210> 1808 <211> 48 <212> DNA <213> Escherichia coli O157:H7 <400> 1808 atagccctgt agggccgctg atccgcggca gtggttttgc ccgtgatt 48 <210> 1809 <211> 48 <212> DNA <213> Escherichia coli O157:H7 <400> 1809 cggtggcgaa gaaactgggc tacagcctga aggattgtat tgcgtttg 48 <210> 1810 <211> 48 <212> DNA <213> Escherichia coli O157:H7 <400> 1810 cgattgcaga gcgaattcat aatgatggat ggctgttggg aagggaag 48 <210> 1811 <211> 47 <212> DNA <213> Escherichia coli O157:H7 <400> 1811 ggcgtaaata tggataaggt cacgtcccct ggggagtgac cttacca 47 <210> 1812 <211> 47 <212> DNA <213> Escherichia coli O157:H7 <400> 1812 atcaacgcgg gatgcgacgc tttcacatca catccggcat ttgctta ４７ ＜２１０＞ １８１３ <212> DNA <213> Escherichia coli O157:H7 <400> 1813 actgcttcta tcgaagctgg tcagaacgaa gttgataaca acggt 45 <210> 1814 <211> 44 <212> DNA <213> Escherichia coli O157:H7 <400> 1814 ggcctacggt tgctctccag cagagttgga taaggcgttt acgc 44 <210> 1815 <211> 44 <212> DNA <213> Escherichia coli O157:H7 <400> 1815 taagttgtct gcgttatgaa taattgctta cagacgccat cgcc ４４ ＜２１０＞ １８１６ ＜２１１＞ ４３ ＜２１２＞ ＤＮＡ ＜２１３＞ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ Ｏ１５７：Ｈ７ ＜４００＞ １８１６ <210> 1817 <211> 43 <212> DNA <213> Escherichia coli O157:H7 <400> 1817 gccgtaagaa acaggagacg gcgcaggtgg cgcggctacc gta 43 <210> 1818 <211> 43 <212> DNA <213> Escherichia coli O157:H7 <400> 1818 agacaatatg gacggctgaa gataactttt ttcattgtat ttg 43 <210> 1819 <211> 42 <212> DNA <213> Escherichia coli O157:H7 <400> 1819 catgatgcct gatacggtct tatcaggcct acccggctat ta 42 <210> 1820 <211> 41 <212> DNA <213> Escherichia coli O157:H7 <400> 1820 ggacaaatgg tacgagcggt aggcctgata agacgcgtta a 41 <210> 1821 <211> 41 <212> DNA <213> Escherichia coli O157:H7 <400> 1821 ttcagcaagt taagatatga acatcaggca aagggcgcaa a 41 <210> 1822 <211> 41 <212> DNA <213> Escherichia coli O157:H7 <400> 1822 gaacctatta tttttttatt ttcatcaaac actgccatcc t 41 <210> 1823 <211> 40 <212> DNA <213> Escherichia coli O157:H7 <400> 1823 tgtgctgtaa gggcgttaga aatagagctc tgaattattt 40 <210> 1824 <211> 39 <212> DNA <213> Escherichia coli O157:H7 <400> 1824 acagccgcag tatcagcagc cacaacagca ggttgcgcc 39 <210> 1825 <211> 39 <212> DNA <213> Escherichia coli O157:H7 <400> 1825 agttgcgccg cagccgcagt atcaacagcc gcaacaacc 39 <210> 1826 <211> 39 <212> DNA <213> Escherichia coli O157:H7 <400> 1826 catagctgta tgggccattg gcctgatgag cgacagtgc ３９ ＜２１０＞ １８２７ ＜２１１＞ ３９ ＜２１２＞ ＤＮＡ ＜２１３＞ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ Ｏ１５７：Ｈ７ agaggctaac cttatggtgt ctatacatag aggggcctc 39 <210> 1828 <211> 39 <212> DNA <213> Escherichia coli O157:H7 <400> 1828 gaataacgac atacccggcg tgcagcctga tatgtcgtt 39 <210> 1829 <211> 38 <212> DNA <213> Escherichia coli O157:H7 <400> 1829 gtaaatagtg ataacttcga cagccagggt aatcatca 38 <210> 1830 <211> 37 <212> DNA <213> Escherichia coli O157:H7 <400> 1830 gatgccgccc tttatttttt actcgctttg tgaagcc ３７ ＜２１０＞ １８３１ ＜２１１＞ ３６ <213> Escherichia coli O157:H7 <400> 1831 cgtcacatct tcagtctgct gaacctgtgg ctttgc 36 <210> 1832 <211> 36 <212> DNA <213> Escherichia coli O157:H7 <400> 1832 cttttcacaa cgctaacatc taataagatt agatat 36 <210> 1833 <211> 34 <212> DNA <213> Escherichia coli O157:H7 <400> 1833 ctggacggtg ctaccgtgga cggtgctacc cacc 34 <210> 1834 <211> 34 <212> DNA <213> Escherichia coli O157:H7 <400> 1834 gcatgtaggc ctgataagcg tagcgcatca ggca ３４ <210> 1835 <211> 34 <212> DNA <213> Escherichia coli O157:H7 <400> 1835 atgaacaaag agcacttcat cagcaatctg aaac 34 <210> 1836 <211> 34 <212> DNA <213> Escherichia coli O157:H7 <400> 1836 tcccggcgtt gttgcgccgg gtagtacaac ttca 34 <210> 1837 <211> 33 <212> DNA <213> Escherichia coli O157:H7 <400> 1837 gcacctcatt gttgtcggcg ctctctgtgt gga 33 <210> 1838 <211> 32 <212> DNA <213> Escherichia coli O157:H7 <400> 1838 aaaatgcctc gcccggtggg cgaggcaaaa tc 32 <210> 1839 <211> 32 <212> DNA <213> Escherichia coli O157:H7 <400> 1839 ctcgacttta attttttcgc tgcccgcttt tg 32 <210> 1840 <211> 30 <212> DNA <213> Escherichia coli O157:H7 <400> 1840 ataatgggcg tcataaaaaa aacgtcagac 30 <210> 1841 <211> 30 <212> DNA <213> Escherichia coli O157:H7 <400> 1841 ggatgatttt aatgatgggt aaaaataaga ３０ ＜２１０＞ １８４２ <212> DNA <213> Escherichia coli O157:H7 <400> 1842 acggtgaaaa ccctattttt ggaggtgaa 29 <210> 1843 <211> 29 <212> DNA <213> Escherichia coli O157:H7 <400> 1843 cgacgcttga cttatctttt gctgtctaa 29 <210> 1844 <211> 29 <212> DNA <213> Escherichia coli O157:H7 <400> 1844 ttgattaaaa tgcccgatag cacacacta ２９ ＜２１０＞ １８４５ ＜２１１＞ ２８ ＜２１２＞ ＤＮＡ ＜２１３＞ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ Ｏ１５７：Ｈ７ ＜４００＞ １８４５ <210> 1846 <211> 27 <212> DNA <213> Escherichia coli O157:H7 <400> 1846 caatccccca ggtcggatag ggcccgg 27 <210> 1847 <211> 26 <212> DNA <213> Escherichia coli O157:H7 <400> 1847 cacaataccg acgaaagagc gggata 26 <210> 1848 <211> 26 <212> DNA <213> Escherichia coli O157:H7 <400> 1848 gtgagcaatg cgaaaaagcc tgttag 26 <210> 1849 <211> 25 <212> DNA <213> Escherichia coli O157:H7 <400> 1849 cggagggcaa atatcctcct taatc 25 <210> 1850 <211> 24 <212> DNA <213> Escherichia coli O157:H7 <400> 1850 gcagaacagc agaacagcag aaca 24 <210> 1851 <211> 24 <212> DNA <213> Escherichia coli O157:H7 <400> 1851 gagccaggtt gtgtgaaggg atgg 24 <210> 1852 <211> 24 <212> DNA <213> Escherichia coli O157:H7 <400> 1852 tcagcacaac cacctgatgc gatc 24 <210> 1853 <211> 23 <212> DNA <213> Escherichia coli O157:H7 <400> 1853 tatttaatgc cggatgcggc gtg 23 <210> 1854 <211> 22 <212> DNA <213> Escherichia coli O157:H7 <400> 1854 cttgcgaagc agactgatac gt 22 <210> 1855 <211> 21 <212> DNA <213> Escherichia coli O157:H7 <400> 1855 gccccttaaa ggccaatcaa c ２１ ＜２１０＞ １８５６ ＜２１１＞ ２１ ＜２１２＞ ＤＮＡ ＜２１３＞ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ Ｏ１５７：Ｈ７ ctgtgtgttg acaaagcgag c 21 <210> 1857 <211> 21 <212> DNA <213> Escherichia coli O157:H7 <400> 1857 aagtactctt tgcaggcagg c 21 <210> 1858 <211> 21 <212> DNA <213> Escherichia coli O157:H7 <400> 1858 cacgcaatat ttatttagcg t 21 <210> 1859 <211> 21 <212> DNA <213> Escherichia coli O157:H7 <400> 1859 atttttgctt tctctgccgg a ２１ ＜２１０＞ １８６０ ＜２１１＞ ２１ <213> Escherichia coli O157:H7 <400> 1860 aaaaagcggc cattttgtgg t 21 <210> 1861 <211> 21 <212> DNA <213> Escherichia coli O157:H7 <400> 1861 gctaacgaaa gttagcagct a 21 <210> 1862 <211> 20 <212> DNA <213> Escherichia coli O157:H7 <400> 1862 ttaattttta cgtagggtgc 20 <210> 1863 <211> 20 <212> DNA <213> Escherichia coli O157:H7 <400> 1863 ttcgggtatt tccagcgtat ２０ <210> 1864 <211> 20 <212> DNA <213> Escherichia coli O157:H7 <400> 1864 gtgtcagtct gcttcgcaag 20 <210> 1865 <211> 1814 <212> DNA <213> Escherichia coli O157:H7 <400> 1865 atgttacgtc ctgtagaaac cccaacccgt gaaatcaaaa aactcgacgg cctgtgggca 60 ttcagtctgg atcgcgaaaa ctgtggaatt gagcagcgtt ggtgggaaag cgcgttacaa 120 gaaagccggg caattgctgt gccaggcagt tttaacgatc agttcgccga tgcagatatt 180 cgtaattatg tgggcaacgt ctggtatcag cgcgaagtct ttataccgaa aggttgggca 240 ggccagcgta tcgtgctgcg tttcgatgcg gtcactcatt acggcaaagt gtgggtcaat 300 aatcaggaag tgatggagca tcagggcggc tatacgccat ttgaagccga tgtcacgccg 360 tatgttattg ccgggaaaag tgtacgtatc acagtttgtg tgaacaacga actgaactgg 420 cagactatcc cgccgggaat ggtgattacc gacgaaaacg gcaagaaaaa gcagtcttac 480 ttccatgatt tctttaacta cgccgggatc catcgcagcg taatgctcta caccacgccg 540 aacacctggg tggacgatat caccgtggtg acgcatgtcg cgcaagactg taaccacgcg 600 tctgttgact ggcaggtggt ggccaatggt gatgtcagcg ttgaactgcg tgatgcggat 660 caacaggtgg ttgcaactgg acaaggggca ccagcgggac tttgcaagtg gtgaatccgc 720 acctctggca accgggtgaa ggttatctct atgaactgta cgtcacagcc aaaagccgga 780 cagagtgtga tatctacccg ctgcgcgtcg gcatccggtc agtggcagtg aagggcgaac 840 agttcctgat caaccacaaa ccgttctact ttactggctt tggccgtcat gaagatgcgg 900 atttgcgcgg caaaggattc gataacgtgc tgatggtgca cgatcacgca ttaatggact 960 ggattggggc caactcctac cgtacctcgc attaccctta cgctgaagag atgctcgact 1020 gggcagatga acatggcatc gtggtgattg atgaaactgc agctgtcggc tttaacctct 1080 ctttaggcat tggtttcgaa gcgggcaaca agccgaaaga actgtacagc gaagaggcag 1140 tcaacgggga aactcagcag gcgcacttac aggcgattaa agagctgata gcgcgtgaca 1200 aaaaccaccc aagcgtggtg atgtggagta ttgccaacga accggatacc cgtccgcaag 1260 gtgcacggga atatttcgcg ccactggcgg aagcaacgcg taaactcgat ccgacgcgtc 1320 cgatcacctg cgtcaatgta atgttctgcg acgctcacac cgataccatc agcgatctct 1380 ttgatgtgct gtgcctgaac cgttattacg gttggtatgt ccaaagcggc gatttggaaa 1440 cggcagagaa ggtactggaa aaagaacttc tggcctggca ggagaaactg catcagccga 1500 ttatcatcac cgaatacggc gtggatacgt tagccgggct gcactcaatg tacaccgaca 1560 tgtggagtga agagtatcag tgtgcatggc tggatatgta tcaccgcgtc tttgatcgcg 1620 tcagcgccgt cgtcggtgaa caggtatgga atttcgccga ttttgcgacc tcgcaaggca 1680 tattgcgcgt tggcggtaac aagaagggga tcttcacccg cgaccgcaaa ccgaagtcgg 1740 cggcttttct gctgcaaaaa cgctggactg gcatgaactt cggtgaaaaa ccgcagcagg 1800 gaggcaaaca atga 1814 <210> 1866 <211> 1521 <212> DNA <213> Escherichia coli O157:H7 <400> 1866 atgatagaaa ccattactca tggtgcagag tggtttatcg ggctgttcca aaagggcgga 60 gaggtgttta ccgggatggt gaccggcatt cttccgctgt tgattagcct gctggttatc 120 ａｔｇａａｃｇｃａｃ ｔｇａｔｔａａｔｔｔ ｔａｔｃｇｇｔｃａｇ ｃａｔ
ｃｇｔａｔｔｇ ａａｃｇｔｔｔｔｇｃ ｔｃａａｃｇｔｔｇｃ １８０ ｇｃｃｇｇｔａａｃｃ ｃｔｇｔｔｔｃｃｃｇ ｔｔａｃｃｔａｃｔｇ ｔｔａ
ｃｃｇｔｇｃａ ｔｔｇｇｃａｃｇｔｔ ｔｇｔｃｔｔｔｔｇｃ ２４０ ａａｔｃｃｇａｔｇａ ｃｃｔｔａａｇｃｃｔ ｇｇｇｔｃｇｃｔｔｔ ａｔｇ
ｃｃｇｇａａａ ａｇｔａｃａａａｃｃ ｃａｇｃｔａｃｔａｃ ３００ ｇｃｇｇｃｇｇｃｃｔ ｃｔｔａｔａｇｃｔｇ ｃｃａｃｔｃａａｔｇ ａａｔ
ｇｇｃｃｔｃｔ ｔｃｃｃｃｃａｔａｔ ｃａａｃｃｃｔｇｇｃ ３６０ ｇａａｃｔｇｔｔｔｇ ｔｔａｔｃｔｔｇｇｃ ａｔｔｇｃｃａｇｃｇ ｇｔｃ
ｔｇａｃａａｃ ｇｃｔｇａａｃｃｔｇ ｃｃａｃｔｔｇｇｃｃ ４２０ ｃａｃｔｇｇｃｇｇｔ ｇａｇｃｔａｔｃｔｇ ｃｔｇｇｔｔｇｇｔｃ ｔｇｇ
ｔｃａｃｃａａ ｃｔｔｃｔｔｃｃｇｃ ｇｇｃｔｇｇｇｔｇａ ４８０ ｃｃｇａｔｃｔｇａｃ ｃａｃｃｇｃｔａｔｔ ｔｔｔｇａｇａａａａ ａｇａ
ｔｇｇｇｃａｔ ｔｃａａｃｔｔｇａａ ｃａａａａａｇｔｔｃ ５４０ ａｔｃｔｇｇｃａｇｇ ａｇｃａａｃａｔｃａ ｔｇａｃｇｃａｔａｔ ｔｃｇ
ｇａｔｃｇａａ ａａａｇｇａａｃｇｇ ｇｇｇｇｃｔｇｇｇｇ ６００ ｃｇｇｃｃｃｇｃｔｔ ｇａｇｃｔｇｇａａａ ｃｃａｃｇｃｃｇｇｇ ｃａａ
ａａａａａｔｃ ｇｔｃｔａｔａｔｃａ ｃｃｃｃｇｃｃｇｇｔ ６６０ ａｃｃｃｇｇｃｃｔｇ ｃｇａｔｔｇｔｃｇａ ｃａａａｃｔｇｇｃａ ｃａｇ
ｃｔｔａｃｔｇ ｇｃｔｇｇｃａｇｇｃ ｔａｔｔｇａｃｇｇａ ７２０ ｔｔｔａａａｇａａｇ ｇｔｇａａｃｃｃｇｃ ｇｇａｇｇｃｇｇａａ ａｔｔ
ｇｇｔｇｔｃｇ ｃｇｇｔａａｔｃｇａ ｃｔｇｔｇｇｃｇｇｃ ７８０ ａｃａｔｔａｃｇｃｔ ｇｃｇｇｃａｔｔｔａ ｔｃｃｇａａａｃｇｇ ｃｇｔ
ａｔｔｃｃｃａ ｃｃａｔｔａａｔａｔ ｃｃａｃｔｃｇａｃｇ ８４０ ｇｇｃａａｇｔｃｃｇ ｇｔｃｃａｃｔｇｇｃ ｇｃａｇｔａｃａｔｔ ｇｔｇ
ｇａａｇａｔａ ｔｔｔａｔｇｔｃｔｃ ｔｇｇｃｇｔａａａａ ９００ ｇａａｇａａａａｃａ ｔｃａｃｔｇｔａｇｔ ｇｇｇｔｇａｔｇｃｇ ａｃａ
ｃｃａｃａａｃ ｃｃｔｃｔｔｃｃｇｔ ｇｇｇｃｃｇｔｇａｃ ９６０ 1020 ggtatgggtt ctgccgttgc cgtgttgttt caatctggtc gtgacaccat cgacactgta 1080 ttaaaaacca ttcttccgtt tatggcattc gtctcggcgc tcattggcat cattatggct 1140 tctggccttg gtgactggat tgcccacggc cttgctccgc tggcgagcca tccactgggt 1200 ctggtcatgc tggcgctcat ctgctccttc ccgctgcttt cacctttcct cggcccaggc 1260 gcagttatcg cacaggttat cggcgtattg attggcgtgc agattggtct cggcaatatt 1320 ccgccgcatc tggctttacc tgcactgttt gccatcaacg cgcaggcggc ctgcgacttc 1380 attccggtcg gtttgtcgct ggcggaagcc cgtcaggaca cggttcgcgt cggtgtccct 1440 tctgtactgg tgagccgctt tttaaccggc gcgccgactg tactgatcgc ctggtttgtc 1500 tccggtttta tctatcaata g 1521

───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.⁷ 識別記号 ＦＩ テーマコート゛(参考） Ａ６１Ｐ 31/04 Ｃ０７Ｋ 16/12 ４Ｂ０６５ Ｃ０７Ｋ 14/245 Ｃ１２Ｍ 1/00 Ａ ４Ｃ０８４ 16/12 Ｃ１２Ｎ 1/15 ４Ｃ０８５ Ｃ１２Ｍ 1/00 1/19 ４Ｃ０８６ Ｃ１２Ｎ 1/15 1/21 ４Ｈ０４５ 1/19 Ｃ１２Ｐ 21/02 Ｃ 1/21 Ｃ１２Ｑ 1/68 Ａ 5/10 Ｇ０１Ｎ 33/15 Ｚ Ｃ１２Ｐ 21/02 33/50 Ｚ Ｃ１２Ｑ 1/68 33/53 Ｄ Ｇ０１Ｎ 33/15 Ｍ 33/50 33/566 33/53 37/00 １０２ Ｃ１２Ｎ 15/00 ＺＮＡＡ 33/566 Ｆ 37/00 １０２ 5/00 Ａ (72)発明者 牧野 耕三 大阪府吹田市山田丘３番１号 大阪大学微 生物病研究所内 (72)発明者 林 哲也 宮崎県宮崎郡清武町大字木原520 宮崎医 科大学微生物学講座内 (72)発明者 大西 真 宮崎県宮崎郡清武町大字木原520 宮崎医 科大学微生物学講座内 (72)発明者 服部 正平 神奈川県相模原市北里１−15−１ 北里大 学理学部内 (72)発明者 黒川 顕 大阪府吹田市山田丘３番１号 大阪大学微 生物病研究所内 Ｆターム(参考） 2G045 AA40 BA11 BB50 DA12 DA13 DA14 DA36 FB02 4B024 AA01 AA13 BA11 BA12 BA38 BA80 CA03 CA09 CA12 DA05 HA14 HA19 4B029 AA07 FA12 4B063 QA07 QA13 QA19 QQ43 QQ44 QQ53 QQ60 QR32 QR36 QR55 QR62 QR82 QS25 4B064 AG30 CA19 CC24 DA15 4B065 AA26Y AA46X AB01 CA24 CA31 CA45 CA46 4C084 AA02 AA06 AA07 AA13 4C085 AA03 BB11 CC07 DD62 DD63 EE01 4C086 AA01 EA16 MA01 MA04 NA14 ZB35 4H045 AA10 AA11 AA20 AA30 BA10 CA11 DA83 DA89 EA31 EA52 FA74

Claims (18)

【特許請求の範囲】
1. 【請求項１】 腸管出血性病原性大腸菌Ｏ１５７：Ｈ７
   に特異的な核酸分子。
2. 【請求項２】 腸管出血性病原性大腸菌Ｏ１５７：Ｈ７
   に特異的な核酸分子であって、（ａ）SEQ ID NO：1, SE
   Q ID NO：132, SEQ ID NO：244, SEQ ID NO：337, SEQI
   D NO：410, SEQ ID NO：484, SEQ ID NO：554, SEQ ID
   NO：630, SEQ ID NO：689, SEQ ID NO：755, SEQ ID N
   O：816, SEQ ID NO：876, SEQ ID NO：927, SEQID NO：
   978, SEQ ID NO：1013, SEQ ID NO：1029, SEQ ID NO：
   1055, SEQ ID NO：1060, SEQ ID NO：1093, SEQ ID N
   O：1128, SEQ ID NO：1157, SEQ ID NO：1191, SEQ ID
   NO：1212, SEQ ID NO：1240, SEQ ID NO：1258, SEQ ID
   NO：1274,SEQ ID NO：1288, SEQ ID NO：1302, SEQ ID
   NO：1309, SEQ ID NO：1321, SEQID NO：1329, SEQ ID
   NO：1338, SEQ ID NO：1348, SEQ ID NO：1359, SEQ I
   D NO：1366, SEQ ID NO：1374, SEQ ID NO：1380, SEQ
   ID NO：1386, SEQ ID NO：1394, SEQ ID NO：1401, SEQ
   ID NO：1408, SEQ ID NO：1411, SEQ ID NO：1418,SEQ
   ID NO：1426, SEQ ID NO：1436, SEQ ID NO：1443, SE
   Q ID NO：1450, SEQID NO：1457, SEQ ID NO：1460, SE
   Q ID NO：1467, SEQ ID NO：1471, SEQ IDNO：1473, SE
   Q ID NO：1478, SEQ ID NO：1487, SEQ ID NO：1489, S
   EQ ID NO：1494, SEQ ID NO：1499, SEQ, ID NO：1501,
   SEQ ID NO：1506, SEQ ID NO：1508, SEQ ID NO：151
   0, SEQ ID NO：1511, SEQ ID NO：1516, SEQ ID NO：15
   20, SEQ ID NO：1526, SEQ ID NO：1532, SEQ ID NO：1
   537, SEQ ID NO：1540, SEQ ID NO：1545, SEQ ID NO：
   1547, SEQ ID NO：1549, SEQ ID NO：1551, SEQ ID N
   O：1553, SEQ ID NO：1555, SEQ ID NO：1558, SEQ ID
   NO：1563, SEQ ID NO：1566, SEQ ID NO：1569, SEQ ID
   NO：1571, SEQ ID NO：1576, SEQ ID NO：1580,SEQ ID
   NO：1584, SEQ ID NO：1587, SEQ ID NO：1591, SEQ I
   D NO：1594, SEQID NO：1596, SEQ ID NO：1599, SEQ I
   D NO：1601, SEQ ID NO：1603, SEQ ID NO：1604, SEQ
   ID NO：1605, SEQ ID NO：1607, SEQ ID NO：1612, SEQ
   ID NO：1615, SEQ ID NO：1617, SEQ ID NO：1619, SE
   Q ID NO：1622, SEQ ID NO：1624,SEQ ID NO：1626, SE
   Q ID NO：1627, SEQ ID NO：1629, SEQ ID NO：1632, S
   EQID NO：1635, SEQ ID NO：1636, SEQ ID NO：1637, S
   EQ ID NO：1639, SEQ IDNO：1640, SEQ ID NO：1643, S
   EQ ID NO：1646, SEQ ID NO：1649, SEQ ID NO：1652,
   SEQ ID NO：1655, SEQ ID NO：1658, SEQ ID NO：1660,
   SEQ ID NO：1662, SEQ ID NO：1664, SEQ ID NO：166
   6, SEQ ID NO：1668, SEQ ID NO：1669, SEQ ID NO：16
   70, SEQ ID NO：1672, SEQ ID NO：1673, SEQ ID NO：1
   675, SEQ IDNO：1677, SEQ ID NO：1680, SEQ ID NO：1
   682, SEQ ID NO：1683, SEQ ID NO：1685, SEQ ID NO：
   1688, SEQ ID NO：1690, SEQ ID NO：1691, SEQ ID N
   O：1694, SEQ ID NO：1696, SEQ ID NO：1699, SEQ ID
   NO：1700, SEQ ID NO：1701,SEQ ID NO：1704, SEQ ID
   NO：1705, SEQ ID NO：1706, SEQ ID NO：1707, SEQID
   NO：1708, SEQ ID NO：1709, SEQ ID NO：1710, SEQ ID
   NO：1711, SEQ ID NO：1712, SEQ ID NO：1713, SEQ I
   D NO：1715, SEQ ID NO：1716, SEQ ID NO：1717, SEQ
   ID NO：1718,, SEQ ID NO：1719, SEQ ID NO：1720, SE
   Q ID NO：1721, SEQ ID NO：1722, SEQ ID NO：1723, S
   EQ ID NO：1724, SEQ ID NO：1725, SEQ ID NO：1726,
   SEQ ID NO：1727, SEQ ID NO：1728, SEQ ID NO：1729,
   SEQ IDNO：1730, SEQ ID NO：1731, SEQ ID NO：1732,
   SEQ ID NO：1733, SEQ ID NO：1734, SEQ ID NO：173
   5, SEQ ID NO：1736, SEQ ID NO：1737, SEQ ID NO：17
   38, SEQ ID NO：1739, SEQ ID NO：1740, SEQ ID NO：1
   741, SEQ ID NO：1742,SEQ ID NO：1743, SEQ ID NO：1
   744, SEQ ID NO：1745, SEQ ID NO：1746, SEQID NO：1
   747, SEQ ID NO：1748, SEQ ID NO：1749, SEQ ID NO：
   1750, SEQ ID NO：1751, SEQ ID NO：1752, SEQ ID N
   O：1753, SEQ ID NO：1754, SEQ ID NO：1755, SEQ ID
   NO：1756, SEQ ID NO：1757, SEQ ID NO：1758, SEQ ID
   NO：1759,SEQ ID NO：1760, SEQ ID NO：1761, SEQ ID
   NO：1762, SEQ ID NO：1763, SEQID NO：1764, SEQ ID
   NO：1765, SEQ ID NO：1766, SEQ ID NO：1767, SEQ I
   DNO：1768, SEQ ID NO：1769, SEQ ID NO：1770, SEQ I
   D NO：1771, SEQ ID NO：1772, SEQ ID NO：1773, SEQ
   ID NO：1774, SEQ ID NO：1775, SEQ ID NO：1776, SEQ
   ID NO：1777, SEQ ID NO：1778, SEQ ID NO：1779, SE
   Q ID NO：1780, SEQ ID NO：1781, SEQ ID NO：1782, S
   EQ ID NO：1783, SEQ ID NO：1784, SEQ IDNO：1785, S
   EQ ID NO：1786, SEQ ID NO：1787, SEQ ID NO：1788,
   SEQ ID NO：1789, SEQ ID NO：1790, SEQ ID NO：1791,
   SEQ ID NO：1792, SEQ ID NO：1793, SEQ ID NO：179
   4, SEQ ID NO：1795, SEQ ID NO：1796, SEQ ID NO：17
   97,SEQ ID NO：1798, SEQ ID NO：1799, SEQ ID NO：18
   00, SEQ ID NO：1801, SEQID NO：1802, SEQ ID NO：18
   03, SEQ ID NO：1804, SEQ ID NO：1805, SEQ ID NO：1
   806, SEQ ID NO：1807, SEQ ID NO：1808, SEQ ID NO：
   1809, SEQ ID NO：1810, SEQ ID NO：1811, SEQ ID N
   O：1812, SEQ ID NO：1813, SEQ ID NO：1814,SEQ ID N
   O：1815, SEQ ID NO：1816, SEQ ID NO：1817, SEQ ID
   NO：1818, SEQID NO：1819, SEQ ID NO：1820, SEQ ID
   NO：1821, SEQ ID NO：1822, SEQ IDNO：1823, SEQ ID
   NO：1824, SEQ ID NO：1825, SEQ ID NO：1826, SEQ ID
   NO：1827, SEQ ID NO：1828, SEQ ID NO：1829, SEQ I
   D NO：1830, SEQ ID NO：1831, SEQ ID NO：1832, SEQ
   ID NO：1833, SEQ ID NO：1834, SEQ ID NO：1835, SEQ
   ID NO：1836, SEQ ID NO：1837, SEQ ID NO：1838, SE
   Q ID NO：1839, SEQ IDNO：1840, SEQ ID NO：1841, SE
   Q ID NO：1842, SEQ ID NO：1843, SEQ ID NO：1844, S
   EQ ID NO：1845, SEQ ID NO：1846, SEQ ID NO：1847,
   SEQ ID NO：1848, SEQ ID NO：1849, SEQ ID NO：1850,
   SEQ ID NO：1851, SEQ ID NO：1852,SEQ ID NO：1853,
   SEQ ID NO：1854, SEQ ID NO：1855, SEQ ID NO：185
   6, SEQID NO：1857, SEQ ID NO：1858, SEQ ID NO：185
   9, SEQ ID NO：1860, SEQ ID NO：1861, SEQ ID NO：18
   62, SEQ ID NO：1863, SEQ ID NO：1864, SEQ ID NO：1
   865, およびSEQ ID NO：1866からなる群から選択される
   ヌクレオチド配列、（ｂ）（ａ）に記載のヌクレオチド
   配列の部分、（ｃ）（ａ）もしくは（ｂ）に記載のヌク
   レオチド配列と相補的なヌクレオチド配列 （ｄ）（ａ）、（ｂ）もしくは（ｃ）に記載のヌクレオ
   チド配列とストリンジェントな条件下でハイブリダイズ
   するヌクレオチド配列を有する請求項１に記載の核酸分
   子。
3. 【請求項３】 腸管出血性病原性大腸菌Ｏ１５７：Ｈ７
   に特異的なポリペプチドをコードする核酸分子であっ
   て、（ａ）SEQ ID NO：2, SEQ ID NO：3, SEQ ID NO：
   4, SEQ ID NO：5, SEQ ID NO：6, SEQ ID NO：7, SEQ I
   D NO：8, SEQ ID NO：9, SEQ ID NO：10, SEQ ID NO：1
   1, SEQ ID NO：12, SEQ ID NO：13, SEQ ID NO：14, SE
   Q ID NO：15, SEQ IDNO：16, SEQ ID NO：17, SEQ ID N
   O：18, SEQ ID NO：19, SEQ ID NO：20, SEQID NO：21,
   SEQ ID NO：22, SEQ ID NO：23, SEQ ID NO：24, SEQ
   ID NO：25,SEQ ID NO：26, SEQ ID NO：27, SEQ ID N
   O：28, SEQ ID NO：29, SEQ ID NO：30, SEQ ID NO：3
   1, SEQ ID NO：32, SEQ ID NO：33, SEQ ID NO：34, SE
   Q ID NO：35, SEQ ID NO：36, SEQ ID NO：37, SEQ ID
   NO：38, SEQ ID NO：39, SEQ IDNO：40, SEQ ID NO：4
   1, SEQ ID NO：42, SEQ ID NO：43, SEQ ID NO：44, SE
   QID NO：45, SEQ ID NO：46, SEQ ID NO：47, SEQ ID N
   O：48, SEQ ID NO：49,SEQ ID NO：50, SEQ ID NO：51,
   SEQ ID NO：52, SEQ ID NO：53, SEQ ID NO：54, SEQ
   ID NO：55, SEQ ID NO：56, SEQ ID NO：57, SEQ ID N
   O：58, SEQ ID NO：59, SEQ ID NO：60, SEQ ID NO：6
   1, SEQ ID NO：62, SEQ ID NO：63, SEQ IDNO：64, SEQ
   ID NO：65, SEQ ID NO：66, SEQ ID NO：67, SEQ ID N
   O：68, SEQID NO：69, SEQ ID NO：70, SEQ ID NO：71,
   SEQ ID NO：72, SEQ ID NO：73,SEQ ID NO：74, SEQ I
   D NO：75, SEQ ID NO：76, SEQ ID NO：77, SEQ ID N
   O：78, SEQ ID NO：79, SEQ ID NO：80, SEQ ID NO：8
   1, SEQ ID NO：82, SEQ ID NO：83, SEQ ID NO：84, SE
   Q ID NO：85, SEQ ID NO：86, SEQ ID NO：87, SEQ IDN
   O：88, SEQ ID NO：89, SEQ ID NO：90, SEQ ID NO：9
   1, SEQ ID NO：92, SEQID NO：93, SEQ ID NO：94, SEQ
   ID NO：95, SEQ ID NO：96, SEQ ID NO：97,SEQ ID N
   O：98, SEQ ID NO：99, SEQ ID NO：100, SEQ ID NO：1
   01, SEQ ID NO：102, SEQ ID NO：103, SEQ ID NO：10
   4, SEQ ID NO：105, SEQ ID NO：106, SEQ ID NO：107,
   SEQ ID NO：108, SEQ ID NO：109, SEQ ID NO：110, S
   EQ ID NO：111, SEQ ID NO：112, SEQ ID NO：113, SEQ
   ID NO：114, SEQ ID NO：115, SEQ ID NO：116, SEQ I
   D NO：117, SEQ ID NO：118, SEQ ID NO：119, SEQ ID
   NO：120, SEQ ID NO：121, SEQ ID NO：122, SEQ ID N
   O：123, SEQ ID NO：124, SEQ ID NO：125, SEQ ID N
   O：126, SEQ ID NO：127, SEQ ID NO：128, SEQ ID N
   O：129, SEQ ID NO：130, SEQ ID NO：131, SEQ ID N
   O：133, SEQ ID NO：134, SEQ ID NO：135, SEQ ID N
   O：136, SEQ ID NO：137, SEQ ID NO：138, SEQ ID N
   O：139, SEQ ID NO：140, SEQ ID NO：141, SEQ ID N
   O：142, SEQ ID NO：143, SEQ ID NO：144, SEQ ID N
   O：145, SEQ ID NO：146, SEQ ID NO：147, SEQ ID N
   O：148, SEQ ID NO：149, SEQ ID NO：150, SEQ ID N
   O：151, SEQ ID NO：152, SEQ ID NO：153, SEQ ID N
   O：154, SEQ ID NO：155, SEQ ID NO：156, SEQ ID N
   O：157, SEQ ID NO：158, SEQ ID NO：159, SEQ ID N
   O：160, SEQ ID NO：161, SEQ ID NO：162, SEQ ID N
   O：163, SEQ ID NO：164, SEQ ID NO：165, SEQ ID N
   O：166, SEQ ID NO：167, SEQ ID NO：168, SEQ ID N
   O：169, SEQ ID NO：170, SEQ ID NO：171, SEQ ID N
   O：172, SEQ ID NO：173, SEQ ID NO：174, SEQ ID N
   O：175, SEQ ID NO：176, SEQ ID NO：177, SEQ ID N
   O：178, SEQ ID NO：179, SEQ ID NO：180, SEQ ID N
   O：181, SEQ ID NO：182, SEQ ID NO：183, SEQ ID N
   O：184, SEQ ID NO：185, SEQ ID NO：186, SEQ ID N
   O：187, SEQ ID NO：188, SEQ ID NO：189, SEQ ID N
   O：190, SEQ ID NO：191, SEQ ID NO：192, SEQ ID N
   O：193, SEQ ID NO：194, SEQ ID NO：195, SEQ ID N
   O：196, SEQ ID NO：197, SEQ ID NO：198, SEQ ID N
   O：199, SEQ ID NO：200, SEQ ID NO：201, SEQ ID N
   O：202, SEQ ID NO：203, SEQ ID NO：204, SEQ ID N
   O：205, SEQ ID NO：206, SEQ ID NO：207, SEQ ID N
   O：208, SEQ ID NO：209, SEQ ID NO：210, SEQ ID N
   O：211, SEQ ID NO：212, SEQ ID NO：213, SEQ ID N
   O：214, SEQ ID NO：215, SEQ ID NO：216, SEQ ID N
   O：217, SEQ ID NO：218, SEQ ID NO：219, SEQ ID N
   O：220, SEQ ID NO：221, SEQ ID NO：222, SEQ ID N
   O：223, SEQ ID NO：224, SEQ ID NO：225, SEQ ID N
   O：226, SEQ ID NO：227, SEQ ID NO：228, SEQ ID N
   O：229, SEQ ID NO：230, SEQ ID NO：231, SEQ ID N
   O：232, SEQ ID NO：233, SEQ ID NO：234, SEQ ID N
   O：235, SEQ ID NO：236, SEQ ID NO：237, SEQ ID N
   O：238, SEQ ID NO：239, SEQ ID NO：240, SEQ ID N
   O：241, SEQ ID NO：242, SEQ ID NO：243, SEQ ID N
   O：245, SEQ ID NO：246, SEQ ID NO：247, SEQ ID N
   O：248, SEQ ID NO：249, SEQ ID NO：250, SEQ ID N
   O：251, SEQ ID NO：252, SEQ ID NO：253, SEQ ID N
   O：254, SEQ ID NO：255, SEQ ID NO：256, SEQ ID N
   O：257, SEQ ID NO：258, SEQ ID NO：259, SEQ ID N
   O：260, SEQ ID NO：261, SEQ ID NO：262, SEQ ID N
   O：263, SEQ ID NO：264, SEQ ID NO：265, SEQ ID N
   O：266, SEQ ID NO：267, SEQ ID NO：268, SEQ ID N
   O：269, SEQ ID NO：270, SEQ ID NO：271, SEQ ID N
   O：272, SEQ ID NO：273, SEQ ID NO：274, SEQ ID N
   O：275, SEQ ID NO：276, SEQ ID NO：277, SEQ ID N
   O：278, SEQ ID NO：279, SEQ ID NO：280, SEQ ID N
   O：281, SEQ ID NO：282, SEQ ID NO：283, SEQ ID N
   O：284, SEQ ID NO：285, SEQ ID NO：286, SEQ ID N
   O：287, SEQ ID NO：288, SEQ ID NO：289, SEQ ID N
   O：290, SEQ ID NO：291, SEQ ID NO：292, SEQ ID N
   O：293, SEQ ID NO：294, SEQ ID NO：295, SEQ ID N
   O：296, SEQ ID NO：297, SEQ ID NO：298, SEQ ID N
   O：299, SEQ ID NO：300, SEQ ID NO：301, SEQ ID N
   O：302, SEQ ID NO：303, SEQ ID NO：304, SEQ ID N
   O：305, SEQ ID NO：306, SEQ ID NO：307, SEQ ID N
   O：308, SEQ ID NO：309, SEQ ID NO：310, SEQ ID N
   O：311, SEQ ID NO：312, SEQ ID NO：313, SEQ ID N
   O：314, SEQ ID NO：315, SEQ ID NO：316, SEQ ID N
   O：317, SEQ ID NO：318, SEQ ID NO：319, SEQ ID N
   O：320, SEQ ID NO：321, SEQ ID NO：322, SEQ ID N
   O：323, SEQ ID NO：324, SEQ ID NO：325, SEQ ID N
   O：326, SEQ ID NO：327, SEQ ID NO：328, SEQ ID N
   O：329, SEQ ID NO：330, SEQ ID NO：331, SEQ ID N
   O：332, SEQ ID NO：333, SEQ ID NO：334, SEQ ID N
   O：335, SEQ ID NO：336, SEQ ID NO：338, SEQ ID N
   O：339, SEQ ID NO：340, SEQ ID NO：341, SEQ ID N
   O：342, SEQ ID NO：343, SEQ ID NO：344, SEQ ID N
   O：345, SEQ ID NO：346, SEQ ID NO：347, SEQ ID N
   O：348, SEQ ID NO：349, SEQ ID NO：350, SEQ ID N
   O：351, SEQ ID NO：352, SEQ ID NO：353, SEQ ID N
   O：354, SEQ ID NO：355, SEQ ID NO：356, SEQ ID N
   O：357, SEQ ID NO：358, SEQ ID NO：359, SEQ ID N
   O：360, SEQ ID NO：361, SEQ ID NO：362, SEQ ID N
   O：363, SEQ ID NO：364, SEQ ID NO：365, SEQ ID N
   O：366, SEQ ID NO：367, SEQ ID NO：368, SEQ ID N
   O：369, SEQ ID NO：370, SEQ ID NO：371, SEQ ID N
   O：372, SEQ ID NO：373, SEQ ID NO：374, SEQ ID N
   O：375, SEQ ID NO：376, SEQ ID NO：377, SEQ ID N
   O：378, SEQ ID NO：379, SEQ ID NO：380, SEQ ID N
   O：381, SEQ ID NO：382, SEQ ID NO：383, SEQ ID N
   O：384, SEQ ID NO：385, SEQ ID NO：386, SEQ ID N
   O：387, SEQ ID NO：388, SEQ ID NO：389, SEQ ID N
   O：390, SEQ ID NO：391, SEQ ID NO：392, SEQ ID N
   O：393, SEQ ID NO：394, SEQ ID NO：395, SEQ ID N
   O：396, SEQ ID NO：397, SEQ ID NO：398, SEQ ID N
   O：399, SEQ ID NO：400, SEQ ID NO：401, SEQ ID N
   O：402, SEQ ID NO：403, SEQ ID NO：404, SEQ ID N
   O：405, SEQ ID NO：406, SEQ ID NO：407, SEQ ID N
   O：408, SEQ ID NO：409, SEQ ID NO：411, SEQ ID N
   O：412, SEQ ID NO：413, SEQ ID NO：414, SEQ ID N
   O：415, SEQ ID NO：416, SEQ ID NO：417, SEQ ID N
   O：418, SEQ ID NO：419, SEQ ID NO：420, SEQ ID N
   O：421, SEQ ID NO：422, SEQ ID NO：423, SEQ ID N
   O：424, SEQ ID NO：425, SEQ ID NO：426, SEQ ID N
   O：427, SEQ ID NO：428, SEQ ID NO：429, SEQ ID N
   O：430, SEQ ID NO：431, SEQ ID NO：432, SEQ ID N
   O：433, SEQ ID NO：434, SEQ ID NO：435, SEQ ID N
   O：436, SEQ ID NO：437, SEQ ID NO：438, SEQ ID N
   O：439, SEQ ID NO：440, SEQ ID NO：441, SEQ ID N
   O：442, SEQ ID NO：443, SEQ ID NO：444, SEQ ID N
   O：445, SEQ ID NO：446, SEQ ID NO：447, SEQ ID N
   O：448, SEQ ID NO：449, SEQ ID NO：450, SEQ ID N
   O：451, SEQ ID NO：452, SEQ ID NO：453, SEQ ID N
   O：454, SEQ ID NO：455, SEQ ID NO：456, SEQ ID N
   O：457, SEQ ID NO：458, SEQ ID NO：459, SEQ ID N
   O：460, SEQ ID NO：461, SEQ ID NO：462, SEQ ID N
   O：463, SEQ ID NO：464, SEQ ID NO：465, SEQ ID N
   O：466, SEQ ID NO：467, SEQ ID NO：468, SEQ ID N
   O：469, SEQ ID NO：470, SEQ ID NO：471, SEQ ID N
   O：472, SEQ ID NO：473, SEQ ID NO：474, SEQ ID N
   O：475, SEQ ID NO：476, SEQ ID NO：477, SEQ ID N
   O：478, SEQ ID NO：479, SEQ ID NO：480, SEQ ID N
   O：481, SEQ ID NO：482, SEQ ID NO：483, SEQ ID N
   O：485, SEQ ID NO：486, SEQ ID NO：487, SEQ ID N
   O：488, SEQ ID NO：489, SEQ ID NO：490, SEQ ID N
   O：491, SEQ ID NO：492, SEQ ID NO：493, SEQ ID N
   O：494, SEQ ID NO：495, SEQ ID NO：496, SEQ ID N
   O：497, SEQ ID NO：498, SEQ ID NO：499, SEQ ID N
   O：500, SEQ ID NO：501, SEQ ID NO：502, SEQ ID N
   O：503, SEQ ID NO：504, SEQ ID NO：505, SEQ ID N
   O：506, SEQ ID NO：507, SEQ ID NO：508, SEQ ID N
   O：509, SEQ ID NO：510, SEQ ID NO：511, SEQ ID N
   O：512, SEQ ID NO：513, SEQ ID NO：514, SEQ ID N
   O：515, SEQ ID NO：516, SEQ ID NO：517, SEQ ID N
   O：518, SEQ ID NO：519, SEQ ID NO：520, SEQ ID N
   O：521, SEQ ID NO：522, SEQ ID NO：523, SEQ ID N
   O：524, SEQ ID NO：525, SEQ ID NO：526, SEQ ID N
   O：527, SEQ ID NO：528, SEQ ID NO：529, SEQ ID N
   O：530, SEQ ID NO：531, SEQ ID NO：532, SEQ ID N
   O：533, SEQ ID NO：534, SＥＱ ＩＤ ＮＯ：535, SE
   Q ID NO：536, SEQ ID NO：537, SEQ ID NO：538, SEQ
   ID NO：539, SEQ ID NO：540, SEQ ID NO：541, SEQ ID
   NO：542, SEQ ID NO：543, SEQ ID NO：544, SEQ ID N
   O：545, SEQ ID NO：546, SEQ ID NO：547, SEQ ID N
   O：548, SEQ ID NO：549, SEQ ID NO：550, SEQ ID N
   O：551, SEQ ID NO：552, SEQ ID NO：553, SEQ ID N
   O：555, SEQ ID NO：556, SEQ ID NO：557, SEQ ID N
   O：558, SEQ ID NO：559, SEQ ID NO：560, SEQ ID N
   O：561, SEQ ID NO：562, SEQ ID NO：563, SEQ ID N
   O：564, SEQ ID NO：565, SEQ ID NO：566, SEQ ID N
   O：567, SEQ ID NO：568, SEQ ID NO：569, SEQ ID N
   O：570, SEQ ID NO：571, SEQ ID NO：572, SEQ ID N
   O：573, SEQ ID NO：574, SEQ ID NO：575, SEQ ID N
   O：576, SEQ ID NO：577, SEQ ID NO：578, SEQ ID N
   O：579, SEQ ID NO：580, SEQ ID NO：581, SEQ ID N
   O：582, SEQ ID NO：583, SEQ ID NO：584, SEQ ID N
   O：585, SEQ ID NO：586, SEQ ID NO：587, SEQ ID N
   O：588, SEQ ID NO：589, SEQ ID NO：590, SEQ ID N
   O：591, SEQ ID NO：592, SEQ ID NO：593, SEQ ID N
   O：594, SEQ ID NO：595, SEQ ID NO：596, SEQ ID N
   O：597, SEQ ID NO：598, SEQ ID NO：599, SEQ ID N
   O：600, SEQ ID NO：601, SEQ ID NO：602, SEQ ID N
   O：603, SEQ ID NO：604, SEQ ID NO：605, SEQ ID N
   O：606, SEQ ID NO：607, SEQ ID NO：608, SEQ ID N
   O：609, SEQ ID NO：610, SEQ ID NO：611, SEQ ID N
   O：612, SEQ ID NO：613, SEQ ID NO：614, SEQ ID N
   O：615, SEQ ID NO：616, SEQ ID NO：617, SEQ ID N
   O：618, SEQ ID NO：619, SEQ ID NO：620, SEQ ID N
   O：621, SEQ ID NO：622, SEQ ID NO：623, SEQ ID N
   O：624, SEQ ID NO：625, SEQ ID NO：626, SEQ ID N
   O：627, SEQ ID NO：628, SEQ ID NO：629, SEQ ID N
   O：631, SEQ ID NO：632, SEQ ID NO：633, SEQ ID N
   O：634, SEQ ID NO：635, SEQ ID NO：636, SEQ ID N
   O：637, SEQ ID NO：638, SEQ ID NO：639, SEQ ID N
   O：640, SEQ ID NO：641, SEQ ID NO：642, SEQ ID N
   O：643, SEQ ID NO：644, SEQ ID NO：645, SEQ ID N
   O：646, SEQ ID NO：647, SEQ ID NO：648, SEQ ID N
   O：649, SEQ ID NO：650, SEQ ID NO：651, SEQ ID N
   O：652, SEQ ID NO：653, SEQ ID NO：654, SEQ ID N
   O：655, SEQ ID NO：656, SEQ ID NO：657, SEQ ID N
   O：658, SEQ ID NO：659, SEQ ID NO：660, SEQ ID N
   O：661, SEQ ID NO：662, SEQ ID NO：663, SEQ ID N
   O：664, SEQ ID NO：665, SEQ ID NO：666, SEQ ID N
   O：667, SEQ ID NO：668, SEQ ID NO：669, SEQ ID N
   O：670, SEQ ID NO：671, SEQ ID NO：672, SEQ ID N
   O：673, SEQ ID NO：674, SEQ ID NO：675, SEQ ID N
   O：676, SEQ ID NO：677, SEQ ID NO：678, SEQ ID N
   O：679, SEQ ID NO：680, SEQ ID NO：681, SEQ ID N
   O：682, SEQ ID NO：683, SEQ ID NO：684, SEQ ID N
   O：685, SEQ ID NO：686, SEQ ID NO：687, SEQ ID N
   O：688, SEQ ID NO：690, SEQ ID NO：691, SEQ ID N
   O：692, SEQ ID NO：693, SEQ ID NO：694, SEQ ID N
   O：695, SEQ ID NO：696, SEQ ID NO：697, SEQ ID N
   O：698, SEQ ID NO：699, SEQ ID NO：700, SEQ ID N
   O：701, SEQ ID NO：702, SEQ ID NO：703, SEQ ID N
   O：704, SEQ ID NO：705, SEQ ID NO：706, SEQ ID N
   O：707, SEQ ID NO：708, SEQ ID NO：709, SEQ ID N
   O：710, SEQ ID NO：711, SEQ ID NO：712, SEQ ID N
   O：713, SEQ ID NO：714, SEQ ID NO：715, SEQ ID N
   O：716, SEQ ID NO：717, SEQ ID NO：718, SEQ ID N
   O：719, SEQ ID NO：720, SEQ ID NO：721, SEQ ID N
   O：722, SEQ ID NO：723, SEQ ID NO：724, SEQ ID N
   O：725, SEQ ID NO：726, SEQ ID NO：727, SEQ ID N
   O：728, SEQ ID NO：729, SEQ ID NO：730, SEQ ID N
   O：731, SEQ ID NO：732, SEQ ID NO：733, SEQ ID N
   O：734, SEQ ID NO：735, SEQ ID NO：736, SEQ ID N
   O：737, SEQ ID NO：738, SEQ ID NO：739, SEQ ID N
   O：740, SEQ ID NO：741, SEQ ID NO：742, SEQ ID N
   O：743, SEQ ID NO：744, SEQ ID NO：745, SEQ ID N
   O：746, SEQ ID NO：747, SEQ ID NO：748, SEQ ID N
   O：749, SEQ ID NO：750, SEQ ID NO：751, SEQ ID N
   O：752, SEQ ID NO：753, SEQ ID NO：754, SEQ ID N
   O：756, SEQ ID NO：757, SEQ ID NO：758, SEQ ID N
   O：759, SEQ ID NO：760, SEQ ID NO：761, SEQ ID N
   O：762, SEQ ID NO：763, SEQ ID NO：764, SEQ ID N
   O：765, SEQ ID NO：766, SEQ ID NO：767, SEQ ID N
   O：768, SEQ ID NO：769, SEQ ID NO：770, SEQ ID N
   O：771, SEQ ID NO：772, SEQ ID NO：773, SEQ ID N
   O：774, SEQ ID NO：775, SEQ ID NO：776, SEQ ID N
   O：777, SEQ ID NO：778, SEQ ID NO：779, SEQ ID N
   O：780, SEQ ID NO：781, SEQ ID NO：782, SEQ ID N
   O：783, SEQ ID NO：784, SEQ ID NO：785, SEQ ID N
   O：786, SEQ ID NO：787, SEQ ID NO：788, SEQ ID N
   O：789, SEQ ID NO：790, SEQ ID NO：791, SEQ ID N
   O：792, SEQ ID NO：793, SEQ ID NO：794, SEQ ID N
   O：795, SEQ ID NO：796, SEQ ID NO：797, SEQ ID N
   O：798, SEQ ID NO：799, SＥＱ ＩＤ ＮＯ：800, SE
   Q ID NO：801, SEQ ID NO：802, SEQ ID NO：803, SEQ
   ID NO：804, SEQ ID NO：805, SEQ ID NO：806, SEQ ID
   NO：807, SEQ ID NO：808, SEQ ID NO：809, SEQ ID N
   O：810, SEQ ID NO：811, SEQ ID NO：812, SEQ ID N
   O：813, SEQ ID NO：814, SEQ ID NO：815, SEQ ID N
   O：817, SEQ ID NO：818, SEQ ID NO：819, SEQ ID N
   O：820, SEQ ID NO：821, SEQ ID NO：822, SEQ ID N
   O：823, SEQ ID NO：824, SEQ ID NO：825, SEQ ID N
   O：826, SEQ ID NO：827, SEQ ID NO：828, SEQ ID N
   O：829, SEQ ID NO：830, SEQ ID NO：831, SEQ ID N
   O：832, SEQ ID NO：833, SEQ ID NO：834, SEQ ID N
   O：835, SEQ ID NO：836, SEQ ID NO：837, SEQ ID N
   O：838, SEQ ID NO：839, SEQ ID NO：840, SEQ ID N
   O：841, SEQ ID NO：842, SEQ ID NO：843, SEQ ID N
   O：844, SEQ ID NO：845, SEQ ID NO：846, SEQ ID N
   O：847, SEQ ID NO：848, SEQ ID NO：849, SEQ ID N
   O：850, SEQ ID NO：851, SEQ ID NO：852, SEQ ID N
   O：853, SEQ ID NO：854, SEQ ID NO：855, SEQ ID N
   O：856, SEQ ID NO：857, SEQ ID NO：858, SEQ ID N
   O：859, SEQ ID NO：860, SEQ ID NO：861, SEQ ID N
   O：862, SEQ ID NO：863, SEQ ID NO：864, SEQ ID N
   O：865, SEQ ID NO：866, SEQ ID NO：867, SEQ ID N
   O：868, SEQ ID NO：869, SEQ ID NO：870, SEQ ID N
   O：871, SEQ ID NO：872, SEQ ID NO：873, SEQ ID N
   O：874, SEQ ID NO：875, SEQ ID NO：877, SEQ ID N
   O：878, SEQ ID NO：879, SEQ ID NO：880, SEQ ID N
   O：881, SEQ ID NO：882, SEQ ID NO：883, SEQ ID N
   O：884, SEQ ID NO：885, SEQ ID NO：886, SEQ ID N
   O：887, SEQ ID NO：888, SEQ ID NO：889, SEQ ID N
   O：890, SEQ ID NO：891, SEQ ID NO：892, SEQ ID N
   O：893, SEQ ID NO：894, SEQ ID NO：895, SEQ ID N
   O：896, SEQ ID NO：897, SEQ ID NO：898, SEQ ID N
   O：899, SEQ ID NO：900, SEQ ID NO：901, SEQ ID N
   O：902, SEQ ID NO：903, SEQ ID NO：904, SEQ ID N
   O：905, SEQ ID NO：906, SEQ ID NO：907, SEQ ID N
   O：908, SEQ ID NO：909, SEQ ID NO：910, SEQ ID N
   O：911, SEQ ID NO：912, SEQ ID NO：913, SEQ ID N
   O：914, SEQ ID NO：915, SEQ ID NO：916, SEQ ID N
   O：917, SEQ ID NO：918, SEQ ID NO：919, SEQ ID N
   O：920, SEQ ID NO：921, SEQ ID NO：922, SEQ ID N
   O：923, SEQ ID NO：924, SEQ ID NO：925, SEQ ID N
   O：926, SEQ ID NO：928, SEQ ID NO：929, SEQ ID N
   O：930, SEQ ID NO：931, SEQ ID NO：932, SEQ ID N
   O：933, SEQ ID NO：934, SEQ ID NO：935, SEQ ID N
   O：936, SEQ ID NO：937, SEQ ID NO：938, SEQ ID N
   O：939, SEQ ID NO：940, SEQ ID NO：941, SEQ ID N
   O：942, SEQ ID NO：943, SEQ ID NO：944, SEQ ID N
   O：945, SEQ ID NO：946, SEQ ID NO：947, SEQ ID N
   O：948, SEQ ID NO：949, SEQ ID NO：950, SEQ ID N
   O：951, SEQ ID NO：952, SEQ ID NO：953, SEQ ID N
   O：954, SEQ ID NO：955, SEQ ID NO：956, SEQ ID N
   O：957, SEQ ID NO：958, SEQ ID NO：959, SEQ ID N
   O：960, SEQ ID NO：961, SEQ ID NO：962, SEQ ID N
   O：963, SEQ ID NO：964, SEQ ID NO：965, SEQ ID N
   O：966, SEQ ID NO：967, SEQ ID NO：968, SEQ ID N
   O：969, SEQ ID NO：970, SEQ ID NO：971, SEQ ID N
   O：972, SEQ ID NO：973, SEQ ID NO：974, SEQ ID N
   O：975, SEQ ID NO：976, SEQ ID NO：977, SEQ ID N
   O：979, SEQ ID NO：980, SEQ ID NO：981, SEQ ID N
   O：982, SEQ ID NO：983, SEQ ID NO：984, SEQ ID N
   O：985, SEQ ID NO：986, SEQ ID NO：987, SEQ ID N
   O：988, SEQ ID NO：989, SEQ ID NO：990, SEQ ID N
   O：991, SEQ ID NO：992, SEQ ID NO：993, SEQ ID N
   O：994, SEQ ID NO：995, SEQ ID NO：996, SEQ ID N
   O：997, SEQ ID NO：998, SEQ ID NO：999, SEQ ID N
   O：1000, SEQ ID NO：1001,SEQ ID NO：1002, SEQ ID N
   O：1003, SEQ ID NO：1004, SEQ ID NO：1005, SEQID N
   O：1006, SEQ ID NO：1007, SEQ ID NO：1008, SEQ ID
   NO：1009, SEQ IDNO：1010, SEQ ID NO：1011, SEQ ID
   NO：1012, SEQ ID NO：1014, SEQ ID NO：1015, SEQ ID
   NO：1016, SEQ ID NO：1017, SEQ ID NO：1018, SEQ I
   D NO：1019, SEQ ID NO：1020, SEQ ID NO：1021, SEQ
   ID NO：1022, SEQ ID NO：1023, SEQ ID NO：1024, SEQ
   ID NO：1025, SEQ ID NO：1026, SEQ ID NO：1027, SE
   Q IDNO：1028, SEQ ID NO：1030, SEQ ID NO：1031, SE
   Q ID NO：1032, SEQ ID NO：1033, SEQ ID NO：1034, S
   EQ ID NO：1035, SEQ ID NO：1036, SEQ ID NO：1037,
   SEQ ID NO：1038, SEQ ID NO：1039, SEQ ID NO：1040,
   SEQ ID NO：1041,SEQ ID NO：1042, SEQ ID NO：1043,
   SEQ ID NO：1044, SEQ ID NO：1045, SEQID NO：1046,
   SEQ ID NO：1047, SEQ ID NO：1048, SEQ ID NO：104
   9, SEQ ID NO：1050, SEQ ID NO：1051, SEQ ID NO：10
   52, SEQ ID NO：1053, SEQ ID NO：1054, SEQ ID NO：1
   056, SEQ ID NO：1057, SEQ ID NO：1058, SEQ ID NO：
   1059,SEQ ID NO：1061, SEQ ID NO：1062, SEQ ID NO：
   1063, SEQ ID NO：1064, SEQID NO：1065, SEQ ID NO：
   1066, SEQ ID NO：1067, SEQ ID NO：1068, SEQ IDNO：
   1069, SEQ ID NO：1070, SEQ ID NO：1071, SEQ ID N
   O：1072, SEQ ID NO：1073, SEQ ID NO：1074, SEQ ID
   NO：1075, SEQ ID NO：1076, SEQ ID NO：1077, SEQ ID
   NO：1078, SEQ ID NO：1079, SEQ ID NO：1080, SEQ I
   D NO：1081, SEQ ID NO：1082, SEQ ID NO：1083, SEQ
   ID NO：1084, SEQ ID NO：1085, SEQ IDNO：1086, SEQ
   ID NO：1087, SEQ ID NO：1088, SEQ ID NO：1089, SEQ
   ID NO：1090, SEQ ID NO：1091, SEQ ID NO：1092, SE
   Q ID NO：1094, SEQ ID NO：1095, SEQ ID NO：1096, S
   EQ ID NO：1097, SEQ ID NO：1098, SEQ ID NO：1099,S
   EQ ID NO：1100, SEQ ID NO：1101, SEQ ID NO：1102,
   SEQ ID NO：1103, SEQID NO：1104, SEQ ID NO：1105,
   SEQ ID NO：1106, SEQ ID NO：1107, SEQ ID NO：1108,
   SEQ ID NO：1109, SEQ ID NO：1110, SEQ ID NO：111
   1, SEQ ID NO：1112, SEQ ID NO：1113, SEQ ID NO：11
   14, SEQ ID NO：1115, SEQ ID NO：1116,SEQ ID NO：11
   17, SEQ ID NO：1118, SEQ ID NO：1119, SEQ ID NO：1
   120, SEQID NO：1121, SEQ ID NO：1122, SEQ ID NO：1
   123, SEQ ID NO：1124, SEQ IDNO：1125, SEQ ID NO：1
   126, SEQ ID NO：1127, SEQ ID NO：1129, SEQ ID NO：
   1130, SEQ ID NO：1131, SEQ ID NO：1132, SEQ ID N
   O：1133, SEQ ID NO：1134, SEQ ID NO：1135, SEQ ID
   NO：1136, SEQ ID NO：1137, SEQ ID NO：1138, SEQ ID
   NO：1139, SEQ ID NO：1140, SEQ ID NO：1141, SEQ I
   D NO：1142, SEQ IDNO：1143, SEQ ID NO：1144, SEQ I
   D NO：1145, SEQ ID NO：1146, SEQ ID NO：1147, SEQ
   ID NO：1148, SEQ ID NO：1149, SEQ ID NO：1150, SEQ
   ID NO：1151, SEQ ID NO：1152, SEQ ID NO：1153, SE
   Q ID NO：1154, SEQ ID NO：1155,SEQ ID NO：1156, SE
   Q ID NO：1158, SEQ ID NO：1159, SEQ ID NO：1160, S
   EQID NO：1161, SEQ ID NO：1162, SEQ ID NO：1163, S
   EQ ID NO：1164, SEQ ID NO：1165, SEQ ID NO：1166,
   SEQ ID NO：1167, SEQ ID NO：1168, SEQ ID NO：1169,
   SEQ ID NO：1170, SEQ ID NO：1171, SEQ ID NO：117
   2, SEQ ID NO：1173,SEQ ID NO：1174, SEQ ID NO：117
   5, SEQ ID NO：1176, SEQ ID NO：1177, SEQID NO：117
   8, SEQ ID NO：1179, SEQ ID NO：1180, SEQ ID NO：11
   81, SEQ IDNO：1182, SEQ ID NO：1183, SEQ ID NO：11
   84, SEQ ID NO：1185, SEQ ID NO：1186, SEQ ID NO：1
   187, SEQ ID NO：1188, SEQ ID NO：1189, SEQ ID NO：
   1190, SEQ ID NO：1192, SEQ ID NO：1193, SEQ ID N
   O：1194, SEQ ID NO：1195, SEQ ID NO：1196, SEQ ID
   NO：1197, SEQ ID NO：1198, SEQ ID NO：1199, SEQ ID
   NO：1200, SEQ ID NO：1201, SEQ ID NO：1202, SEQ ID
   NO：1203, SEQ ID NO：1204, SEQ ID NO：1205, SEQ I
   D NO：1206, SEQ ID NO：1207, SEQ ID NO：1208, SEQ
   ID NO：1209, SEQ ID NO：1210, SEQ ID NO：1211, SEQ
   ID NO：1213,SEQ ID NO：1214, SEQ ID NO：1215, SEQ
   ID NO：1216, SEQ ID NO：1217, SEQID NO：1218, SEQ
   ID NO：1219, SEQ ID NO：1220, SEQ ID NO：1221, SE
   Q ID NO：1222, SEQ ID NO：1223, SEQ ID NO：1224, S
   EQ ID NO：1225, SEQ ID NO：1226, SEQ ID NO：1227,
   SEQ ID NO：1228, SEQ ID NO：1229, SEQ ID NO：1230,
   SEQ ID NO：1231, SEQ ID NO：1232, SEQ ID NO：1233,
   SEQ ID NO：1234, SEQID NO：1235, SEQ ID NO：1236,
   SEQ ID NO：1237, SEQ ID NO：1238, SEQ IDNO：1239,
   SEQ ID NO：1241, SEQ ID NO：1242, SEQ ID NO：124
   3, SEQ ID NO：1244, SEQ ID NO：1245, SEQ ID NO：12
   46, SEQ ID NO：1247, SEQ ID NO：1248, SEQ ID NO：1
   249, SEQ ID NO：1250, SEQ ID NO：1251, SEQ ID NO：
   1252, SEQ ID NO：1253, SEQ ID NO：1254, SEQ ID N
   O：1255, SEQ ID NO：1256, SEQ IDNO：1257, SEQ ID N
   O：1259, SEQ ID NO：1260, SEQ ID NO：1261, SEQ ID
   NO：1262, SEQ ID NO：1263, SEQ ID NO：1264, SEQ ID
   NO：1265, SEQ ID NO：1266, SEQ ID NO：1267, SEQ I
   D NO：1268, SEQ ID NO：1269, SEQ ID NO：1270,SEQ I
   D NO：1271, SEQ ID NO：1272, SEQ ID NO：1273, SEQ
   ID NO：1275, SEQID NO：1276, SEQ ID NO：1277, SEQ
   ID NO：1278, SEQ ID NO：1279, SEQ ID NO：1280, SEQ
   ID NO：1281, SEQ ID NO：1282, SEQ ID NO：1283, SE
   Q ID NO：1284, SEQ ID NO：1285, SEQ ID NO：1286, S
   EQ ID NO：1287, SEQ ID NO：1289,SEQ ID NO：1290, S
   EQ ID NO：1291, SEQ ID NO：1292, SEQ ID NO：1293,
   SEQID NO：1294, SEQ ID NO：1295, SEQ ID NO：1296,
   SEQ ID NO：1297, SEQ IDNO：1298, SEQ ID NO：1299,
   SEQ ID NO：1300, SEQ ID NO：1301, SEQ ID NO：1303,
   SEQ ID NO：1304, SEQ ID NO：1305, SEQ ID NO：130
   6, SEQ ID NO：1307, SEQ ID NO：1308, SEQ ID NO：13
   10, SEQ ID NO：1311, SEQ ID NO：1312, SEQ ID NO：1
   313, SEQ ID NO：1314, SEQ ID NO：1315, SEQ ID NO：
   1316, SEQ IDNO：1317, SEQ ID NO：1318, SEQ ID NO：
   1319, SEQ ID NO：1320, SEQ ID NO：1322, SEQ ID N
   O：1323, SEQ ID NO：1324, SEQ ID NO：1325, SEQ ID
   NO：1326, SEQ ID NO：1327, SEQ ID NO：1328, SEQ ID
   NO：1330, SEQ ID NO：1331,SEQ ID NO：1332, SEQ ID
   NO：1333, SEQ ID NO：1334, SEQ ID NO：1335, SEQID
   NO：1336, SEQ ID NO：1337, SEQ ID NO：1339, SEQ I
   D NO：1340, SEQ ID NO：1341, SEQ ID NO：1342, SEQ
   ID NO：1343, SEQ ID NO：1344, SEQ ID NO：1345, SEQ
   ID NO：1346, SEQ ID NO：1347, SEQ ID NO：1349, SE
   Q ID NO：1350,SEQ ID NO：1351, SEQ ID NO：1352, SE
   Q ID NO：1353, SEQ ID NO：1354, SEQID NO：1355, SE
   Q ID NO：1356, SEQ ID NO：1357, SEQ ID NO：1358, S
   EQ IDNO：1360, SEQ ID NO：1361, SEQ ID NO：1362, S
   EQ ID NO：1363, SEQ ID NO：1364, SEQ ID NO：1365,
   SEQ ID NO：1367, SEQ ID NO：1368, SEQ ID NO：1369,
   SEQ ID NO：1370, SEQ ID NO：1371, SEQ ID NO：137
   5, SEQ ID NO：1376, SEQ ID NO：1377, SEQ ID NO：13
   78, SEQ ID NO：1379, SEQ ID NO：1381, SEQ IDNO：13
   82, SEQ ID NO：1383, SEQ ID NO：1384, SEQ ID NO：1
   385, SEQ ID NO：1387, SEQ ID NO：1388, SEQ ID NO：
   1389, SEQ ID NO：1390, SEQ ID NO：1391, SEQ ID N
   O：1392, SEQ ID NO：1393, SEQ ID NO：1395, SEQ ID
   NO：1396,SEQ ID NO：1397, SEQ ID NO：1398, SEQ ID
   NO：1399, SEQ ID NO：1400, SEQID NO：1402, SEQ ID
   NO：1403, SEQ ID NO：1404, SEQ ID NO：1405, SEQ ID
   NO：1406, SEQ ID NO：1407, SEQ ID NO：1409, SEQ I
   D NO：1410, SEQ ID NO：1412, SEQ ID NO：1413, SEQ
   ID NO：1414, SEQ ID NO：1415, SEQ ID NO：1416,SEQ
   ID NO：1417, SEQ ID NO：1419, SEQ ID NO：1420, SEQ
   ID NO：1421, SEQID NO：1422, SEQ ID NO：1423, SEQ
   ID NO：1424, SEQ ID NO：1425, SEQ IDNO：1427, SEQ
   ID NO：1428, SEQ ID NO：1429, SEQ ID NO：1430, SE
   Q ID NO：1431, SEQ ID NO：1432, SEQ ID NO：1433, S
   EQ ID NO：1434, SEQ ID NO：1435, SEQ ID NO：1437,
   SEQ ID NO：1438, SEQ ID NO：1439, SEQ ID NO：1440,
   SEQ ID NO：1441, SEQ ID NO：1442, SEQ ID NO：144
   4, SEQ ID NO：1445, SEQ IDNO：1446, SEQ ID NO：144
   7, SEQ ID NO：1448, SEQ ID NO：1449, SEQ ID NO：14
   51, SEQ ID NO：1452, SEQ ID NO：1453, SEQ ID NO：1
   454, SEQ ID NO：1455, SEQ ID NO：1456, SEQ ID NO：
   1458, SEQ ID NO：1459, SEQ ID NO：1461,SEQ ID NO：
   1462, SEQ ID NO：1463, SEQ ID NO：1464, SEQ ID N
   O：1465, SEQＩＤ ＮＯ：1466, SEQ ID NO：1468, SEQ
   ID NO：1469, SEQ ID NO：1470, SEQ ID NO：1472, SE
   Q ID NO：1474, SEQ ID NO：1475, SEQ ID NO：1476, S
   EQ ID NO：1477, SEQ ID NO：1479, SEQ ID NO：1480,
   SEQ ID NO：1481, SEQ ID NO：1482,SEQ ID NO：1483,
   SEQ ID NO：1484, SEQ ID NO：1485, SEQ ID NO：1486,
   SEQID NO：1488, SEQ ID NO：1490, SEQ ID NO：1491,
   SEQ ID NO：1492, SEQ IDNO：1493, SEQ ID NO：1495,
   SEQ ID NO：1496, SEQ ID NO：1497, SEQ ID NO：149
   8, SEQ ID NO：1500, SEQ ID NO：1502, SEQ ID NO：15
   03, SEQ ID NO：1504, SEQ ID NO：1505, SEQ ID NO：1
   507, SEQ ID NO：1509, SEQ ID NO：1512, SEQ ID NO：
   1513, SEQ ID NO：1514, SEQ ID NO：1515, SEQ ID N
   O：1517, SEQ IDNO：1518, SEQ ID NO：1519, SEQ ID N
   O：1521, SEQ ID NO：1522, SEQ ID NO：1523, SEQ ID
   NO：1524, SEQ ID NO：1525, SEQ ID NO：1527, SEQ ID
   NO：1528, SEQ ID NO：1529, SEQ ID NO：1530, SEQ I
   D NO：1531, SEQ ID NO：1533,SEQ ID NO：1534, SEQ I
   D NO：1535, SEQ ID NO：1536, SEQ ID NO：1538, SEQI
   D NO：1539, SEQ ID NO：1541, SEQ ID NO：1542, SEQ
   ID NO：1543, SEQ ID NO：1544, SEQ ID NO：1546, SEQ
   ID NO：1548, SEQ ID NO：1550, SEQ ID NO：1552, SE
   Q ID NO：1554, SEQ ID NO：1556, SEQ ID NO：1557, S
   EQ ID NO：1559,SEQ ID NO：1560, SEQ ID NO：1561, S
   EQ ID NO：1562, SEQ ID NO：1564, SEQID NO：1565, S
   EQ ID NO：1567, SEQ ID NO：1568, SEQ ID NO：1570,
   SEQ IDNO：1572, SEQ ID NO：1573, SEQ ID NO：1574,
   SEQ ID NO：1575, SEQ ID NO：1577, SEQ ID NO：1578,
   SEQ ID NO：1579, SEQ ID NO：1581, SEQ ID NO：158
   2, SEQ ID NO：1583, SEQ ID NO：1585, SEQ ID NO：15
   86, SEQ ID NO：1588, SEQ ID NO：1589, SEQ ID NO：1
   590, SEQ ID NO：1592, SEQ ID NO：1593, SEQ IDNO：1
   595, SEQ ID NO：1597, SEQ ID NO：1598, SEQ ID NO：
   1600, SEQ ID NO：1602, SEQ ID NO：1606, SEQ ID N
   O：1608, SEQ ID NO：1609, SEQ ID NO：1610, SEQ ID
   NO：1611, SEQ ID NO：1613, SEQ ID NO：1614, SEQ ID
   NO：1616,SEQ ID NO：1618, SEQ ID NO：1620, SEQ ID
   NO：1621, SEQ ID NO：1623, SEQID NO：1625, SEQ ID
   NO：1628, SEQ ID NO：1630, SEQ ID NO：1631, SEQ I
   D NO：1633, SEQ ID NO：1634, SEQ ID NO：1638, SEQ
   ID NO：1641, SEQ ID NO：1642, SEQ ID NO：1644, SEQ
   ID NO：1645, SEQ ID NO：1647, SEQ ID NO：1648,SEQ
   ID NO：1650, SEQ ID NO：1651, SEQ ID NO：1653, SE
   Q ID NO：1654, SEQID NO：1656, SEQ ID NO：1657, SE
   Q ID NO：1659, SEQ ID NO：1661, SEQ IDNO：1663, SE
   Q ID NO：1665, SEQ ID NO：1667, SEQ ID NO：1671, S
   EQ ID NO：1674, SEQ ID NO：1676, SEQ ID NO：1678,
   SEQ ID NO：1679, SEQ ID NO：1681, SEQ ID NO：1684,
   SEQ ID NO：1686, SEQ ID NO：1687, SEQ ID NO：168
   9, SEQ ID NO：1692, SEQ ID NO：1693, SEQ ID NO：16
   95, SEQ ID NO：1697, SEQ IDNO：1698, SEQ ID NO：17
   02, およびSEQ ID NO：1703からなる群から選択される
   アミノ酸配列もしくはその部分、または（ｂ）（ａ）の
   アミノ酸配列において、数個のアミノ酸が欠失、置換ま
   たは付加されたアミノ酸配列からなるポリペプチドをコ
   ードする請求項１に記載の核酸分子。
4. 【請求項４】 腸管出血性病原性大腸菌Ｏ１５７：Ｈ７
   に特異的なポリペプチド。
5. 【請求項５】 （ａ）SEQ ID NO：2, SEQ ID NO：3, SE
   Q ID NO：4, SEQ IDNO：5, SEQ ID NO：6, SEQ ID NO：
   7, SEQ ID NO：8, SEQ ID NO：9, SEQ ID NO：10, SEQ
   ID NO：11, SEQ ID NO：12, SEQ ID NO：13, SEQ ID N
   O：14, SEQ ID NO：15, SEQ ID NO：16, SEQ ID NO：1
   7, SEQ ID NO：18, SEQ ID NO：19, SEQ ID NO：20, SE
   Q ID NO：21, SEQ ID NO：22, SEQ ID NO：23, SEQ ID
   NO：24,SEQ ID NO：25, SEQ ID NO：26, SEQ ID NO：2
   7, SEQ ID NO：28, SEQ ID NO：29, SEQ ID NO：30, SE
   Q ID NO：31, SEQ ID NO：32, SEQ ID NO：33, SEQ ID
   NO：34, SEQ ID NO：35, SEQ ID NO：36, SEQ ID NO：3
   7, SEQ ID NO：38, SEQ ID NO：39, SEQ ID NO：40, SE
   Q ID NO：41, SEQ ID NO：42, SEQ ID NO：43, SEQ ID
   NO：44, SEQ ID NO：45, SEQ ID NO：46, SEQ ID NO：4
   7, SEQ ID NO：48,SEQ ID NO：49, SEQ ID NO：50, SEQ
   ID NO：51, SEQ ID NO：52, SEQ ID NO：53, SEQ ID N
   O：54, SEQ ID NO：55, SEQ ID NO：56, SEQ ID NO：5
   7, SEQ ID NO：58, SEQ ID NO：59, SEQ ID NO：60, SE
   Q ID NO：61, SEQ ID NO：62, SEQ ID NO：63, SEQ ID
   NO：64, SEQ ID NO：65, SEQ ID NO：66, SEQ ID NO：6
   7, SEQ ID NO：68, SEQ ID NO：69, SEQ ID NO：70, SE
   Q ID NO：71, SEQ ID NO：72,SEQ ID NO：73, SEQ ID N
   O：74, SEQ ID NO：75, SEQ ID NO：76, SEQ ID NO：7
   7, SEQ ID NO：78, SEQ ID NO：79, SEQ ID NO：80, SE
   Q ID NO：81, SEQ ID NO：82, SEQ ID NO：83, SEQ ID
   NO：84, SEQ ID NO：85, SEQ ID NO：86, SEQ ID NO：8
   7, SEQ ID NO：88, SEQ ID NO：89, SEQ ID NO：90, SE
   Q ID NO：91, SEQ ID NO：92, SEQ ID NO：93, SEQ ID
   NO：94, SEQ ID NO：95, SEQ ID NO：96,SEQ ID NO：9
   7, SEQ ID NO：98, SEQ ID NO：99, SEQ ID NO：100, S
   EQ ID NO：101, SEQ ID NO：102, SEQ ID NO：103, SEQ
   ID NO：104, SEQ ID NO：105, SEQ ID NO：106, SEQ I
   D NO：107, SEQ ID NO：108, SEQ ID NO：109, SEQ ID
   NO：110, SEQ ID NO：111, SEQ ID NO：112, SEQ ID N
   O：113, SEQ ID NO：114, SEQ ID NO：115, SEQ ID N
   O：116, SEQ ID NO：117, SEQ ID NO：118, SEQ ID N
   O：119, SEQ ID NO：120, SEQ ID NO：121, SEQ ID N
   O：122, SEQ ID NO：123, SEQ ID NO：124, SEQ ID N
   O：125, SEQ ID NO：126, SEQ ID NO：127, SEQ ID N
   O：128, SEQ ID NO：129, SEQ ID NO：130, SEQ ID N
   O：131, SEQ ID NO：133, SEQ ID NO：134, SEQ ID N
   O：135, SEQ ID NO：136, SEQ ID NO：137, SEQ ID N
   O：138, SEQ ID NO：139, SEQ ID NO：140, SEQ ID N
   O：141, SEQ ID NO：142, SEQ ID NO：143, SEQ ID N
   O：144, SEQ ID NO：145, SEQ ID NO：146, SEQ ID N
   O：147, SEQ ID NO：148, SEQ ID NO：149, SEQ ID N
   O：150, SEQ ID NO：151, SEQ ID NO：152, SEQ ID N
   O：153, SEQ ID NO：154, SEQ ID NO：155, SEQ ID N
   O：156, SEQ ID NO：157, SEQ ID NO：158, SEQ ID N
   O：159, SEQ ID NO：160, SEQ ID NO：161, SEQ ID N
   O：162, SEQ ID NO：163, SEQ ID NO：164, SEQ ID N
   O：165, SEQ ID NO：166, SEQ ID NO：167, SEQ ID N
   O：168, SEQ ID NO：169, SEQ ID NO：170, SEQ ID N
   O：171, SEQ ID NO：172, SEQ ID NO：173, SEQ ID N
   O：174, SEQ ID NO：175, SEQ ID NO：176, SEQ ID N
   O：177, SEQ ID NO：178, SEQ ID NO：179, SEQ ID N
   O：180, SEQ ID NO：181, SEQ ID NO：182, SEQ ID N
   O：183, SEQ ID NO：184, SEQ ID NO：185, SEQ ID N
   O：186, SEQ ID NO：187, SEQ ID NO：188, SEQ ID N
   O：189, SEQ ID NO：190, SEQ ID NO：191, SEQ ID N
   O：192, SEQ ID NO：193, SEQ ID NO：194, SEQ ID N
   O：195, SEQ ID NO：196, SEQ ID NO：197, SEQ ID N
   O：198, SEQ ID NO：199, SEQ ID NO：200, SEQ ID N
   O：201, SEQ ID NO：202, SEQ ID NO：203, SEQ ID N
   O：204, SEQ ID NO：205, SEQ ID NO：206, SEQ ID N
   O：207, SEQ ID NO：208, SEQ ID NO：209, SEQ ID N
   O：210, SEQ ID NO：211, SEQ ID NO：212, SEQ ID N
   O：213, SEQ ID NO：214, SEQ ID NO：215, SEQ ID N
   O：216, SEQ ID NO：217, SEQ ID NO：218, SEQ ID N
   O：219, SEQ ID NO：220, SEQ ID NO：221, SEQ ID N
   O：222, SEQ ID NO：223, SEQ ID NO：224, SEQ ID N
   O：225, SEQ ID NO：226, SEQ ID NO：227, SEQ ID N
   O：228, SEQ ID NO：229, SEQ ID NO：230, SEQ ID N
   O：231, SEQ ID NO：232, SEQ ID NO：233, SEQ ID N
   O：234, SEQ ID NO：235, SEQ ID NO：236, SEQ ID N
   O：237, SEQ ID NO：238, SEQ ID NO：239, SEQ ID N
   O：240, SEQ ID NO：241, SEQ ID NO：242, SEQ ID N
   O：243, SEQ ID NO：245, SEQ ID NO：246, SEQ ID N
   O：247, SEQ ID NO：248, SEQ ID NO：249, SEQ ID N
   O：250, SEQ ID NO：251, SEQ ID NO：252, SEQ ID N
   O：253, SEQ ID NO：254, SEQ ID NO：255, SEQ ID N
   O：256, SEQ ID NO：257, SEQ ID NO：258, SEQ ID N
   O：259, SEQ ID NO：260, SEQ ID NO：261, SEQ ID N
   O：262, SEQ ID NO：263, SEQ ID NO：264, SEQ ID N
   O：265, SEQ ID NO：266, SEQ ID NO：267, SEQ ID N
   O：268, SEQ ID NO：269, SEQ ID NO：270, SEQ ID N
   O：271, SEQ ID NO：272, SEQ ID NO：273, SEQ ID N
   O：274, SEQ ID NO：275, SEQ ID NO：276, SEQ ID N
   O：277, SEQ ID NO：278, SEQ ID NO：279, SEQ ID N
   O：280, SEQ ID NO：281, SEQ ID NO：282, SEQ ID N
   O：283, SEQ ID NO：284, SEQ ID NO：285, SEQ ID N
   O：286, SEQ ID NO：287, SEQ ID NO：288, SEQ ID N
   O：289, SEQ ID NO：290, SEQ ID NO：291, SEQ ID N
   O：292, SEQ ID NO：293, SEQ ID NO：294, SEQ ID N
   O：295, SEQ ID NO：296, SEQ ID NO：297, SEQ ID N
   O：298, SEQ ID NO：299, SEQ ID NO：300, SEQ ID N
   O：301, SEQ ID NO：302, SEQ ID NO：303, SEQ ID N
   O：304, SEQ ID NO：305, SEQ ID NO：306, SEQ ID N
   O：307, SEQ ID NO：308, SEQ ID NO：309, SEQ ID N
   O：310, SEQ ID NO：311, SEQ ID NO：312, SEQ ID N
   O：313, SEQ ID NO：314, SEQ ID NO：315, SEQ ID N
   O：316, SEQ ID NO：317, SEQ ID NO：318, SEQ ID N
   O：319, SEQ ID NO：320, SEQ ID NO：321, SEQ ID N
   O：322, SEQ ID NO：323, SEQ ID NO：324, SEQ ID N
   O：325, SEQ ID NO：326, SEQ ID NO：327, SEQ ID N
   O：328, SEQ ID NO：329, SEQ ID NO：330, SEQ ID N
   O：331, SEQ ID NO：332, SEQ ID NO：333, SEQ ID N
   O：334, SEQ ID NO：335, SEQ ID NO：336, SEQ ID N
   O：338, SEQ ID NO：339, SEQ ID NO：340, SEQ ID N
   O：341, SEQ ID NO：342, SＥＱ ＩＤ ＮＯ：343, SE
   Q ID NO：344, SEQ ID NO：345, SEQ ID NO：346, SEQ
   ID NO：347, SEQ ID NO：348, SEQ ID NO：349, SEQ ID
   NO：350, SEQ ID NO：351, SEQ ID NO：352, SEQ ID N
   O：353, SEQ ID NO：354, SEQ ID NO：355, SEQ ID N
   O：356, SEQ ID NO：357, SEQ ID NO：358, SEQ ID N
   O：359, SEQ ID NO：360, SEQ ID NO：361, SEQ ID N
   O：362, SEQ ID NO：363, SEQ ID NO：364, SEQ ID N
   O：365, SEQ ID NO：366, SEQ ID NO：367, SEQ ID N
   O：368, SEQ ID NO：369, SEQ ID NO：370, SEQ ID N
   O：371, SEQ ID NO：372, SEQ ID NO：373, SEQ ID N
   O：374, SEQ ID NO：375, SEQ ID NO：376, SEQ ID N
   O：377, SEQ ID NO：378, SEQ ID NO：379, SEQ ID N
   O：380, SEQ ID NO：381, SEQ ID NO：382, SEQ ID N
   O：383, SEQ ID NO：384, SEQ ID NO：385, SEQ ID N
   O：386, SEQ ID NO：387, SEQ ID NO：388, SEQ ID N
   O：389, SEQ ID NO：390, SEQ ID NO：391, SEQ ID N
   O：392, SEQ ID NO：393, SEQ ID NO：394, SEQ ID N
   O：395, SEQ ID NO：396, SEQ ID NO：397, SEQ ID N
   O：398, SEQ ID NO：399, SEQ ID NO：400, SEQ ID N
   O：401, SEQ ID NO：402, SEQ ID NO：403, SEQ ID N
   O：404, SEQ ID NO：405, SEQ ID NO：406, SEQ ID N
   O：407, SEQ ID NO：408, SEQ ID NO：409, SEQ ID N
   O：411, SEQ ID NO：412, SEQ ID NO：413, SEQ ID N
   O：414, SEQ ID NO：415, SEQ ID NO：416, SEQ ID N
   O：417, SEQ ID NO：418, SEQ ID NO：419, SEQ ID N
   O：420, SEQ ID NO：421, SEQ ID NO：422, SEQ ID N
   O：423, SEQ ID NO：424, SEQ ID NO：425, SEQ ID N
   O：426, SEQ ID NO：427, SEQ ID NO：428, SEQ ID N
   O：429, SEQ ID NO：430, SEQ ID NO：431, SEQ ID N
   O：432, SEQ ID NO：433, SEQ ID NO：434, SEQ ID N
   O：435, SEQ ID NO：436, SEQ ID NO：437, SEQ ID N
   O：438, SEQ ID NO：439, SEQ ID NO：440, SEQ ID N
   O：441, SEQ ID NO：442, SEQ ID NO：443, SEQ ID N
   O：444, SEQ ID NO：445, SEQ ID NO：446, SEQ ID N
   O：447, SEQ ID NO：448, SEQ ID NO：449, SEQ ID N
   O：450, SEQ ID NO：451, SEQ ID NO：452, SEQ ID N
   O：453, SEQ ID NO：454, SEQ ID NO：455, SEQ ID N
   O：456, SEQ ID NO：457, SEQ ID NO：458, SEQ ID N
   O：459, SEQ ID NO：460, SEQ ID NO：461, SEQ ID N
   O：462, SEQ ID NO：463, SEQ ID NO：464, SEQ ID N
   O：465, SEQ ID NO：466, SEQ ID NO：467, SEQ ID N
   O：468, SEQ ID NO：469, SEQ ID NO：470, SEQ ID N
   O：471, SEQ ID NO：472, SEQ ID NO：473, SEQ ID N
   O：474, SEQ ID NO：475, SEQ ID NO：476, SEQ ID N
   O：477, SEQ ID NO：478, SEQ ID NO：479, SEQ ID N
   O：480, SEQ ID NO：481, SEQ ID NO：482, SEQ ID N
   O：483, SEQ ID NO：485, SEQ ID NO：486, SEQ ID N
   O：487, SEQ ID NO：488, SEQ ID NO：489, SEQ ID N
   O：490, SEQ ID NO：491, SEQ ID NO：492, SEQ ID N
   O：493, SEQ ID NO：494, SEQ ID NO：495, SEQ ID N
   O：496, SEQ ID NO：497, SEQ ID NO：498, SEQ ID N
   O：499, SEQ ID NO：500, SEQ ID NO：501, SEQ ID N
   O：502, SEQ ID NO：503, SEQ ID NO：504, SEQ ID N
   O：505, SEQ ID NO：506, SEQ ID NO：507, SEQ ID N
   O：508, SEQ ID NO：509, SEQ ID NO：510, SEQ ID N
   O：511, SEQ ID NO：512, SEQ ID NO：513, SEQ ID N
   O：514, SEQ ID NO：515, SEQ ID NO：516, SEQ ID N
   O：517, SEQ ID NO：518, SEQ ID NO：519, SEQ ID N
   O：520, SEQ ID NO：521, SEQ ID NO：522, SEQ ID N
   O：523, SEQ ID NO：524, SEQ ID NO：525, SEQ ID N
   O：526, SEQ ID NO：527, SEQ ID NO：528, SEQ ID N
   O：529, SEQ ID NO：530, SEQ ID NO：531, SEQ ID N
   O：532, SEQ ID NO：533, SEQ ID NO：534, SEQ ID N
   O：535, SEQ ID NO：536, SEQ ID NO：537, SEQ ID N
   O：538, SEQ ID NO：539, SEQ ID NO：540, SEQ ID N
   O：541, SEQ ID NO：542, SEQ ID NO：543, SEQ ID N
   O：544, SEQ ID NO：545, SEQ ID NO：546, SEQ ID N
   O：547, SEQ ID NO：548, SEQ ID NO：549, SEQ ID N
   O：550, SEQ ID NO：551, SEQ ID NO：552, SEQ ID N
   O：553, SEQ ID NO：555, SEQ ID NO：556, SEQ ID N
   O：557, SEQ ID NO：558, SEQ ID NO：559, SEQ ID N
   O：560, SEQ ID NO：561, SEQ ID NO：562, SEQ ID N
   O：563, SEQ ID NO：564, SEQ ID NO：565, SEQ ID N
   O：566, SEQ ID NO：567, SEQ ID NO：568, SEQ ID N
   O：569, SEQ ID NO：570, SEQ ID NO：571, SEQ ID N
   O：572, SEQ ID NO：573, SEQ ID NO：574, SEQ ID N
   O：575, SEQ ID NO：576, SEQ ID NO：577, SEQ ID N
   O：578, SEQ ID NO：579, SEQ ID NO：580, SEQ ID N
   O：581, SEQ ID NO：582, SEQ ID NO：583, SEQ ID N
   O：584, SEQ ID NO：585, SEQ ID NO：586, SEQ ID N
   O：587, SEQ ID NO：588, SEQ ID NO：589, SEQ ID N
   O：590, SEQ ID NO：591, SEQ ID NO：592, SEQ ID N
   O：593, SEQ ID NO：594, SEQ ID NO：595, SEQ ID N
   O：596, SEQ ID NO：597, SEQ ID NO：598, SEQ ID N
   O：599, SEQ ID NO：600, SEQ ID NO：601, SEQ ID N
   O：602, SEQ ID NO：603, SEQ ID NO：604, SEQ ID N
   O：605, SEQ ID NO：606, SＥＱ ＩＤ ＮＯ：607, SE
   Q ID NO：608, SEQ ID NO：609, SEQ ID NO：610, SEQ
   ID NO：611, SEQ ID NO：612, SEQ ID NO：613, SEQ ID
   NO：614, SEQ ID NO：615, SEQ ID NO：616, SEQ ID N
   O：617, SEQ ID NO：618, SEQ ID NO：619, SEQ ID N
   O：620, SEQ ID NO：621, SEQ ID NO：622, SEQ ID N
   O：623, SEQ ID NO：624, SEQ ID NO：625, SEQ ID N
   O：626, SEQ ID NO：627, SEQ ID NO：628, SEQ ID N
   O：629, SEQ ID NO：631, SEQ ID NO：632, SEQ ID N
   O：633, SEQ ID NO：634, SEQ ID NO：635, SEQ ID N
   O：636, SEQ ID NO：637, SEQ ID NO：638, SEQ ID N
   O：639, SEQ ID NO：640, SEQ ID NO：641, SEQ ID N
   O：642, SEQ ID NO：643, SEQ ID NO：644, SEQ ID N
   O：645, SEQ ID NO：646, SEQ ID NO：647, SEQ ID N
   O：648, SEQ ID NO：649, SEQ ID NO：650, SEQ ID N
   O：651, SEQ ID NO：652, SEQ ID NO：653, SEQ ID N
   O：654, SEQ ID NO：655, SEQ ID NO：656, SEQ ID N
   O：657, SEQ ID NO：658, SEQ ID NO：659, SEQ ID N
   O：660, SEQ ID NO：661, SEQ ID NO：662, SEQ ID N
   O：663, SEQ ID NO：664, SEQ ID NO：665, SEQ ID N
   O：666, SEQ ID NO：667, SEQ ID NO：668, SEQ ID N
   O：669, SEQ ID NO：670, SEQ ID NO：671, SEQ ID N
   O：672, SEQ ID NO：673, SEQ ID NO：674, SEQ ID N
   O：675, SEQ ID NO：676, SEQ ID NO：677, SEQ ID N
   O：678, SEQ ID NO：679, SEQ ID NO：680, SEQ ID N
   O：681, SEQ ID NO：682, SEQ ID NO：683, SEQ ID N
   O：684, SEQ ID NO：685, SEQ ID NO：686, SEQ ID N
   O：687, SEQ ID NO：688, SEQ ID NO：690, SEQ ID N
   O：691, SEQ ID NO：692, SEQ ID NO：693, SEQ ID N
   O：694, SEQ ID NO：695, SEQ ID NO：696, SEQ ID N
   O：697, SEQ ID NO：698, SEQ ID NO：699, SEQ ID N
   O：700, SEQ ID NO：701, SEQ ID NO：702, SEQ ID N
   O：703, SEQ ID NO：704, SEQ ID NO：705, SEQ ID N
   O：706, SEQ ID NO：707, SEQ ID NO：708, SEQ ID N
   O：709, SEQ ID NO：710, SEQ ID NO：711, SEQ ID N
   O：712, SEQ ID NO：713, SEQ ID NO：714, SEQ ID N
   O：715, SEQ ID NO：716, SEQ ID NO：717, SEQ ID N
   O：718, SEQ ID NO：719, SEQ ID NO：720, SEQ ID N
   O：721, SEQ ID NO：722, SEQ ID NO：723, SEQ ID N
   O：724, SEQ ID NO：725, SEQ ID NO：726, SEQ ID N
   O：727, SEQ ID NO：728, SEQ ID NO：729, SEQ ID N
   O：730, SEQ ID NO：731, SEQ ID NO：732, SEQ ID N
   O：733, SEQ ID NO：734, SEQ ID NO：735, SEQ ID N
   O：736, SEQ ID NO：737, SEQ ID NO：738, SEQ ID N
   O：739, SEQ ID NO：740, SEQ ID NO：741, SEQ ID N
   O：742, SEQ ID NO：743, SEQ ID NO：744, SEQ ID N
   O：745, SEQ ID NO：746, SEQ ID NO：747, SEQ ID N
   O：748, SEQ ID NO：749, SEQ ID NO：750, SEQ ID N
   O：751, SEQ ID NO：752, SEQ ID NO：753, SEQ ID N
   O：754, SEQ ID NO：756, SEQ ID NO：757, SEQ ID N
   O：758, SEQ ID NO：759, SEQ ID NO：760, SEQ ID N
   O：761, SEQ ID NO：762, SEQ ID NO：763, SEQ ID N
   O：764, SEQ ID NO：765, SEQ ID NO：766, SEQ ID N
   O：767, SEQ ID NO：768, SEQ ID NO：769, SEQ ID N
   O：770, SEQ ID NO：771, SEQ ID NO：772, SEQ ID N
   O：773, SEQ ID NO：774, SEQ ID NO：775, SEQ ID N
   O：776, SEQ ID NO：777, SEQ ID NO：778, SEQ ID N
   O：779, SEQ ID NO：780, SEQ ID NO：781, SEQ ID N
   O：782, SEQ ID NO：783, SEQ ID NO：784, SEQ ID N
   O：785, SEQ ID NO：786, SEQ ID NO：787, SEQ ID N
   O：788, SEQ ID NO：789, SEQ ID NO：790, SEQ ID N
   O：791, SEQ ID NO：792, SEQ ID NO：793, SEQ ID N
   O：794, SEQ ID NO：795, SEQ ID NO：796, SEQ ID N
   O：797, SEQ ID NO：798, SEQ ID NO：799, SEQ ID N
   O：800, SEQ ID NO：801, SEQ ID NO：802, SEQ ID N
   O：803, SEQ ID NO：804, SEQ ID NO：805, SEQ ID N
   O：806, SEQ ID NO：807, SEQ ID NO：808, SEQ ID N
   O：809, SEQ ID NO：810, SEQ ID NO：811, SEQ ID N
   O：812, SEQ ID NO：813, SEQ ID NO：814, SEQ ID N
   O：815, SEQ ID NO：817, SEQ ID NO：818, SEQ ID N
   O：819, SEQ ID NO：820, SEQ ID NO：821, SEQ ID N
   O：822, SEQ ID NO：823, SEQ ID NO：824, SEQ ID N
   O：825, SEQ ID NO：826, SEQ ID NO：827, SEQ ID N
   O：828, SEQ ID NO：829, SEQ ID NO：830, SEQ ID N
   O：831, SEQ ID NO：832, SEQ ID NO：833, SEQ ID N
   O：834, SEQ ID NO：835, SEQ ID NO：836, SEQ ID N
   O：837, SEQ ID NO：838, SEQ ID NO：839, SEQ ID N
   O：840, SEQ ID NO：841, SEQ ID NO：842, SEQ ID N
   O：843, SEQ ID NO：844, SEQ ID NO：845, SEQ ID N
   O：846, SEQ ID NO：847, SEQ ID NO：848, SEQ ID N
   O：849, SEQ ID NO：850, SEQ ID NO：851, SEQ ID N
   O：852, SEQ ID NO：853, SEQ ID NO：854, SEQ ID N
   O：855, SEQ ID NO：856, SEQ ID NO：857, SEQ ID N
   O：858, SEQ ID NO：859, SEQ ID NO：860, SEQ ID N
   O：861, SEQ ID NO：862, SEQ ID NO：863, SEQ ID N
   O：864, SEQ ID NO：865, SEQ ID NO：866, SEQ ID N
   O：867, SEQ ID NO：868, SEQ ID NO：869, SEQ ID N
   O：870, SEQ ID NO：871, SＥＱ ＩＤ ＮＯ：872, SE
   Q ID NO：873, SEQ ID NO：874, SEQ ID NO：875, SEQ
   ID NO：877, SEQ ID NO：878, SEQ ID NO：879, SEQ ID
   NO：880, SEQ ID NO：881, SEQ ID NO：882, SEQ ID N
   O：883, SEQ ID NO：884, SEQ ID NO：885, SEQ ID N
   O：886, SEQ ID NO：887, SEQ ID NO：888, SEQ ID N
   O：889, SEQ ID NO：890, SEQ ID NO：891, SEQ ID N
   O：892, SEQ ID NO：893, SEQ ID NO：894, SEQ ID N
   O：895, SEQ ID NO：896, SEQ ID NO：897, SEQ ID N
   O：898, SEQ ID NO：899, SEQ ID NO：900, SEQ ID N
   O：901, SEQ ID NO：902, SEQ ID NO：903, SEQ ID N
   O：904, SEQ ID NO：905, SEQ ID NO：906, SEQ ID N
   O：907, SEQ ID NO：908, SEQ ID NO：909, SEQ ID N
   O：910, SEQ ID NO：911, SEQ ID NO：912, SEQ ID N
   O：913, SEQ ID NO：914, SEQ ID NO：915, SEQ ID N
   O：916, SEQ ID NO：917, SEQ ID NO：918, SEQ ID N
   O：919, SEQ ID NO：920, SEQ ID NO：921, SEQ ID N
   O：922, SEQ ID NO：923, SEQ ID NO：924, SEQ ID N
   O：925, SEQ ID NO：926, SEQ ID NO：928, SEQ ID N
   O：929, SEQ ID NO：930, SEQ ID NO：931, SEQ ID N
   O：932, SEQ ID NO：933, SEQ ID NO：934, SEQ ID N
   O：935, SEQ ID NO：936, SEQ ID NO：937, SEQ ID N
   O：938, SEQ ID NO：939, SEQ ID NO：940, SEQ ID N
   O：941, SEQ ID NO：942, SEQ ID NO：943, SEQ ID N
   O：944, SEQ ID NO：945, SEQ ID NO：946, SEQ ID N
   O：947, SEQ ID NO：948, SEQ ID NO：949, SEQ ID N
   O：950, SEQ ID NO：951, SEQ ID NO：952, SEQ ID N
   O：953, SEQ ID NO：954, SEQ ID NO：955, SEQ ID N
   O：956, SEQ ID NO：957, SEQ ID NO：958, SEQ ID N
   O：959, SEQ ID NO：960, SEQ ID NO：961, SEQ ID N
   O：962, SEQ ID NO：963, SEQ ID NO：964, SEQ ID N
   O：965, SEQ ID NO：966, SEQ ID NO：967, SEQ ID N
   O：968, SEQ ID NO：969, SEQ ID NO：970, SEQ ID N
   O：971, SEQ ID NO：972, SEQ ID NO：973, SEQ ID N
   O：974, SEQ ID NO：975, SEQ ID NO：976, SEQ ID N
   O：977, SEQ ID NO：979, SEQ ID NO：980, SEQ ID N
   O：981, SEQ ID NO：982, SEQ ID NO：983, SEQ ID N
   O：984, SEQ ID NO：985, SEQ ID NO：986, SEQ ID N
   O：987, SEQ ID NO：988, SEQ ID NO：989, SEQ ID N
   O：990, SEQ ID NO：991, SEQ ID NO：992, SEQ ID N
   O：993, SEQ ID NO：994, SEQ ID NO：995, SEQ ID N
   O：996, SEQ ID NO：997, SEQ ID NO：998, SEQ ID N
   O：999, SEQ ID NO：1000,SEQ ID NO：1001, SEQ ID N
   O：1002, SEQ ID NO：1003, SEQ ID NO：1004, SEQＩＤ
   ＮＯ：1005, SEQ ID NO：1006, SEQ ID NO：1007, SE
   Q ID NO：1008, SEQ ID NO：1009, SEQ ID NO：1010, S
   EQ ID NO：1011, SEQ ID NO：1012, SEQ ID NO：1014,
   SEQ ID NO：1015, SEQ ID NO：1016, SEQ ID NO：1017,
   SEQ ID NO：1018,SEQ ID NO：1019, SEQ ID NO：1020,
   SEQ ID NO：1021, SEQ ID NO：1022, SEQID NO：1023,
   SEQ ID NO：1024, SEQ ID NO：1025, SEQ ID NO：102
   6, SEQ IDNO：1027, SEQ ID NO：1028, SEQ ID NO：103
   0, SEQ ID NO：1031, SEQ ID NO：1032, SEQ ID NO：10
   33, SEQ ID NO：1034, SEQ ID NO：1035, SEQ ID NO：1
   036, SEQ ID NO：1037, SEQ ID NO：1038, SEQ ID NO：
   1039, SEQ ID NO：1040, SEQ ID NO：1041, SEQ ID N
   O：1042, SEQ ID NO：1043, SEQ ID NO：1044, SEQ IDN
   O：1045, SEQ ID NO：1046, SEQ ID NO：1047, SEQ ID
   NO：1048, SEQ ID NO：1049, SEQ ID NO：1050, SEQ ID
   NO：1051, SEQ ID NO：1052, SEQ ID NO：1053, SEQ I
   D NO：1054, SEQ ID NO：1056, SEQ ID NO：1057, SEQ
   ID NO：1058,SEQ ID NO：1059, SEQ ID NO：1061, SEQ
   ID NO：1062, SEQ ID NO：1063, SEQID NO：1064, SEQ
   ID NO：1065, SEQ ID NO：1066, SEQ ID NO：1067, SEQ
   ID NO：1068, SEQ ID NO：1069, SEQ ID NO：1070, SE
   Q ID NO：1071, SEQ ID NO：1072, SEQ ID NO：1073, S
   EQ ID NO：1074, SEQ ID NO：1075, SEQ ID NO：1076,S
   EQ ID NO：1077, SEQ ID NO：1078, SEQ ID NO：1079,
   SEQ ID NO：1080, SEQID NO：1081, SEQ ID NO：1082,
   SEQ ID NO：1083, SEQ ID NO：1084, SEQ IDNO：1085,
   SEQ ID NO：1086, SEQ ID NO：1087, SEQ ID NO：1088,
   SEQ ID NO：1089, SEQ ID NO：1090, SEQ ID NO：109
   1, SEQ ID NO：1092, SEQ ID NO：1094, SEQ ID NO：10
   95, SEQ ID NO：1096, SEQ ID NO：1097, SEQ ID NO：1
   098, SEQ ID NO：1099, SEQ ID NO：1100, SEQ ID NO：
   1101, SEQ ID NO：1102, SEQ IDNO：1103, SEQ ID NO：
   1104, SEQ ID NO：1105, SEQ ID NO：1106, SEQ ID N
   O：1107, SEQ ID NO：1108, SEQ ID NO：1109, SEQ ID
   NO：1110, SEQ ID NO：1111, SEQ ID NO：1112, SEQ ID
   NO：1113, SEQ ID NO：1114, SEQ ID NO：1115,SEQ ID
   NO：1116, SEQ ID NO：1117, SEQ ID NO：1118, SEQ I
   D NO：1119, SEQID NO：1120, SEQ ID NO：1121, SEQ I
   D NO：1122, SEQ ID NO：1123, SEQ ID NO：1124, SEQ
   ID NO：1125, SEQ ID NO：1126, SEQ ID NO：1127, SEQ
   ID NO：1129, SEQ ID NO：1130, SEQ ID NO：1131, SE
   Q ID NO：1132, SEQ ID NO：1133,SEQ ID NO：1134, SE
   Q ID NO：1135, SEQ ID NO：1136, SEQ ID NO：1137, S
   EQID NO：1138, SEQ ID NO：1139, SEQ ID NO：1140, S
   EQ ID NO：1141, SEQ IDNO：1142, SEQ ID NO：1143, S
   EQ ID NO：1144, SEQ ID NO：1145, SEQ ID NO：1146,
   SEQ ID NO：1147, SEQ ID NO：1148, SEQ ID NO：1149,
   SEQ ID NO：1150, SEQ ID NO：1151, SEQ ID NO：115
   2, SEQ ID NO：1153, SEQ ID NO：1154, SEQ ID NO：11
   55, SEQ ID NO：1156, SEQ ID NO：1158, SEQ ID NO：1
   159, SEQ IDNO：1160, SEQ ID NO：1161, SEQ ID NO：1
   162, SEQ ID NO：1163, SEQ ID NO：1164, SEQ ID NO：
   1165, SEQ ID NO：1166, SEQ ID NO：1167, SEQ ID N
   O：1168, SEQ ID NO：1169, SEQ ID NO：1170, SEQ ID
   NO：1171, SEQ ID NO：1172,SEQ ID NO：1173, SEQ ID
   NO：1174, SEQ ID NO：1175, SEQ ID NO：1176, SEQID
   NO：1177, SEQ ID NO：1178, SEQ ID NO：1179, SEQ ID
   NO：1180, SEQ ID NO：1181, SEQ ID NO：1182, SEQ I
   D NO：1183, SEQ ID NO：1184, SEQ ID NO：1185, SEQ
   ID NO：1186, SEQ ID NO：1187, SEQ ID NO：1188, SEQ
   ID NO：1189,SEQ ID NO：1190, SEQ ID NO：1192, SEQ
   ID NO：1193, SEQ ID NO：1194, SEQID NO：1195, SEQ
   ID NO：1196, SEQ ID NO：1197, SEQ ID NO：1198, SE
   Q IDNO：1199, SEQ ID NO：1200, SEQ ID NO：1201, SE
   Q ID NO：1202, SEQ ID NO：1203, SEQ ID NO：1204, S
   EQ ID NO：1205, SEQ ID NO：1206, SEQ ID NO：1207,
   SEQ ID NO：1208, SEQ ID NO：1209, SEQ ID NO：1210,
   SEQ ID NO：1211, SEQ ID NO：1213, SEQ ID NO：121
   4, SEQ ID NO：1215, SEQ ID NO：1216, SEQ IDNO：121
   7, SEQ ID NO：1218, SEQ ID NO：1219, SEQ ID NO：12
   20, SEQ ID NO：1221, SEQ ID NO：1222, SEQ ID NO：1
   223, SEQ ID NO：1224, SEQ ID NO：1225, SEQ ID NO：
   1226, SEQ ID NO：1227, SEQ ID NO：1228, SEQ ID N
   O：1229,SEQ ID NO：1230, SEQ ID NO：1231, SEQ ID N
   O：1232, SEQ ID NO：1233, SEQID NO：1234, SEQ ID N
   O：1235, SEQ ID NO：1236, SEQ ID NO：1237, SEQ ID
   NO：1238, SEQ ID NO：1239, SEQ ID NO：1241, SEQ ID
   NO：1242, SEQ ID NO：1243, SEQ ID NO：1244, SEQ I
   D NO：1245, SEQ ID NO：1246, SEQ ID NO：1247,SEQ I
   D NO：1248, SEQ ID NO：1249, SEQ ID NO：1250, SEQ
   ID NO：1251, SEQID NO：1252, SEQ ID NO：1253, SEQ
   ID NO：1254, SEQ ID NO：1255, SEQ IDNO：1256, SEQ
   ID NO：1257, SEQ ID NO：1259, SEQ ID NO：1260, SEQ
   ID NO：1261, SEQ ID NO：1262, SEQ ID NO：1263, SE
   Q ID NO：1264, SEQ ID NO：1265, SEQ ID NO：1266, S
   EQ ID NO：1267, SEQ ID NO：1268, SEQ ID NO：1269,
   SEQ ID NO：1270, SEQ ID NO：1271, SEQ ID NO：1272,
   SEQ ID NO：1273, SEQ IDNO：1275, SEQ ID NO：1276,
   SEQ ID NO：1277, SEQ ID NO：1278, SEQ ID NO：127
   9, SEQ ID NO：1280, SEQ ID NO：1281, SEQ ID NO：12
   82, SEQ ID NO：1283, SEQ ID NO：1284, SEQ ID NO：1
   285, SEQ ID NO：1286, SEQ ID NO：1287,SEQ ID NO：1
   289, SEQ ID NO：1290, SEQ ID NO：1291, SEQ ID NO：
   1292, SEQID NO：1293, SEQ ID NO：1294, SEQ ID NO：
   1295, SEQ ID NO：1296, SEQ ID NO：1297, SEQ ID N
   O：1298, SEQ ID NO：1299, SEQ ID NO：1300, SEQ ID
   NO：1301, SEQ ID NO：1303, SEQ ID NO：1304, SEQ ID
   NO：1305, SEQ ID NO：1306,SEQ ID NO：1307, SEQ ID
   NO：1308, SEQ ID NO：1310, SEQ ID NO：1311, SEQID
   NO：1312, SEQ ID NO：1313, SEQ ID NO：1314, SEQ I
   D NO：1315, SEQ IDNO：1316, SEQ ID NO：1317, SEQ I
   D NO：1318, SEQ ID NO：1319, SEQ ID NO：1320, SEQ
   ID NO：1322, SEQ ID NO：1323, SEQ ID NO：1324, SEQ
   ID NO：1325, SEQ ID NO：1326, SEQ ID NO：1327, SE
   Q ID NO：1328, SEQ ID NO：1330, SEQ ID NO：1331, S
   EQ ID NO：1332, SEQ ID NO：1333, SEQ ID NO：1334,
   SEQ IDNO：1335, SEQ ID NO：1336, SEQ ID NO：1337,
   SEQ ID NO：1339, SEQ ID NO：1340, SEQ ID NO：1341,
   SEQ ID NO：1342, SEQ ID NO：1343, SEQ ID NO：134
   4, SEQ ID NO：1345, SEQ ID NO：1346, SEQ ID NO：13
   47, SEQ ID NO：1349,SEQ ID NO：1350, SEQ ID NO：13
   51, SEQ ID NO：1352, SEQ ID NO：1353, SEQID NO：13
   54, SEQ ID NO：1355, SEQ ID NO：1356, SEQ ID NO：1
   357, SEQ ID NO：1358, SEQ ID NO：1360, SEQ ID NO：
   1361, SEQ ID NO：1362, SEQ ID NO：1363, SEQ ID N
   O：1364, SEQ ID NO：1365, SEQ ID NO：1367, SEQ ID
   NO：1368,SEQ ID NO：1369, SEQ ID NO：1370, SEQ ID
   NO：1371, SEQ ID NO：1375, SEQID NO：1376, SEQ ID
   NO：1377, SEQ ID NO：1378, SEQ ID NO：1379, SEQ ID
   NO：1381, SEQ ID NO：1382, SEQ ID NO：1383, SEQ ID
   NO：1384, SEQ ID NO：1385, SEQ ID NO：1387, SEQ I
   D NO：1388, SEQ ID NO：1389, SEQ ID NO：1390, SEQ
   ID NO：1391, SEQ ID NO：1392, SEQ ID NO：1393, SEQ
   ID NO：1395, SEQ ID NO：1396, SEQ ID NO：1397, SE
   Q ID NO：1398, SEQ ID NO：1399, SEQ IDＮＯ：1400,
   SEQ ID NO：1402, SEQ ID NO：1403, SEQ ID NO：1404,
   SEQ ID NO：1405, SEQ ID NO：1406, SEQ ID NO：140
   7, SEQ ID NO：1409, SEQ ID NO：1410, SEQ ID NO：14
   12, SEQ ID NO：1413, SEQ ID NO：1414, SEQ ID NO：1
   415,SEQ ID NO：1416, SEQ ID NO：1417, SEQ ID NO：1
   419, SEQ ID NO：1420, SEQID NO：1421, SEQ ID NO：1
   422, SEQ ID NO：1423, SEQ ID NO：1424, SEQ ID NO：
   1425, SEQ ID NO：1427, SEQ ID NO：1428, SEQ ID N
   O：1429, SEQ ID NO：1430, SEQ ID NO：1431, SEQ ID
   NO：1432, SEQ ID NO：1433, SEQ ID NO：1434,SEQ ID
   NO：1435, SEQ ID NO：1437, SEQ ID NO：1438, SEQ ID
   NO：1439, SEQID NO：1440, SEQ ID NO：1441, SEQ ID
   NO：1442, SEQ ID NO：1444, SEQ IDNO：1445, SEQ ID
   NO：1446, SEQ ID NO：1447, SEQ ID NO：1448, SEQ I
   D NO：1449, SEQ ID NO：1451, SEQ ID NO：1452, SEQ
   ID NO：1453, SEQ ID NO：1454, SEQ ID NO：1455, SEQ
   ID NO：1456, SEQ ID NO：1458, SEQ ID NO：1459, SE
   Q ID NO：1461, SEQ ID NO：1462, SEQ ID NO：1463, S
   EQ ID NO：1464, SEQ IDNO：1465, SEQ ID NO：1466, S
   EQ ID NO：1468, SEQ ID NO：1469, SEQ ID NO：1470,
   SEQ ID NO：1472, SEQ ID NO：1474, SEQ ID NO：1475,
   SEQ ID NO：1476, SEQ ID NO：1477, SEQ ID NO：147
   9, SEQ ID NO：1480, SEQ ID NO：1481,SEQ ID NO：148
   2, SEQ ID NO：1483, SEQ ID NO：1484, SEQ ID NO：14
   85, SEQID NO：1486, SEQ ID NO：1488, SEQ ID NO：14
   90, SEQ ID NO：1491, SEQ ID NO：1492, SEQ ID NO：1
   493, SEQ ID NO：1495, SEQ ID NO：1496, SEQ ID NO：
   1497, SEQ ID NO：1498, SEQ ID NO：1500, SEQ ID N
   O：1502, SEQ ID NO：1503,SEQ ID NO：1504, SEQ ID N
   O：1505, SEQ ID NO：1507, SEQ ID NO：1509, SEQID N
   O：1512, SEQ ID NO：1513, SEQ ID NO：1514, SEQ ID
   NO：1515, SEQ IDNO：1517, SEQ ID NO：1518, SEQ ID
   NO：1519, SEQ ID NO：1521, SEQ ID NO：1522, SEQ ID
   NO：1523, SEQ ID NO：1524, SEQ ID NO：1525, SEQ I
   D NO：1527, SEQ ID NO：1528, SEQ ID NO：1529, SEQ
   ID NO：1530, SEQ ID NO：1531, SEQ ID NO：1533, SEQ
   ID NO：1534, SEQ ID NO：1535, SEQ ID NO：1536, SE
   Q IDNO：1538, SEQ ID NO：1539, SEQ ID NO：1541, SE
   Q ID NO：1542, SEQ ID NO：1543, SEQ ID NO：1544, S
   EQ ID NO：1546, SEQ ID NO：1548, SEQ ID NO：1550,
   SEQ ID NO：1552, SEQ ID NO：1554, SEQ ID NO：1556,
   SEQ ID NO：1557,SEQ ID NO：1559, SEQ ID NO：1560,
   SEQ ID NO：1561, SEQ ID NO：1562, SEQID NO：1564,
   SEQ ID NO：1565, SEQ ID NO：1567, SEQ ID NO：156
   8, SEQ ID NO：1570, SEQ ID NO：1572, SEQ ID NO：15
   73, SEQ ID NO：1574, SEQ ID NO：1575, SEQ ID NO：1
   577, SEQ ID NO：1578, SEQ ID NO：1579, SEQ ID NO：
   1581,SEQ ID NO：1582, SEQ ID NO：1583, SEQ ID NO：
   1585, SEQ ID NO：1586, SEQID NO：1588, SEQ ID NO：
   1589, SEQ ID NO：1590, SEQ ID NO：1592, SEQ IDNO：
   1593, SEQ ID NO：1595, SEQ ID NO：1597, SEQ ID N
   O：1598, SEQ ID NO：1600, SEQ ID NO：1602, SEQ ID
   NO：1606, SEQ ID NO：1608, SEQ ID NO：1609, SEQ ID
   NO：1610, SEQ ID NO：1611, SEQ ID NO：1613, SEQ I
   D NO：1614, SEQ ID NO：1616, SEQ ID NO：1618, SEQ
   ID NO：1620, SEQ ID NO：1621, SEQ IDNO：1623, SEQ
   ID NO：1625, SEQ ID NO：1628, SEQ ID NO：1630, SEQ
   ID NO：1631, SEQ ID NO：1633, SEQ ID NO：1634, SE
   Q ID NO：1638, SEQ ID NO：1641, SEQ ID NO：1642, S
   EQ ID NO：1644, SEQ ID NO：1645, SEQ ID NO：1647,S
   EQ ID NO：1648, SEQ ID NO：1650, SEQ ID NO：1651,
   SEQ ID NO：1653, SEQID NO：1654, SEQ ID NO：1656,
   SEQ ID NO：1657, SEQ ID NO：1659, SEQ ID NO：1661,
   SEQ ID NO：1663, SEQ ID NO：1665, SEQ ID NO：166
   7, SEQ ID NO：1671, SEQ ID NO：1674, SEQ ID NO：16
   76, SEQ ID NO：1678, SEQ ID NO：1679,SEQ ID NO：16
   81, SEQ ID NO：1684, SEQ ID NO：1686, SEQ ID NO：1
   687, SEQID NO：1689, SEQ ID NO：1692, SEQ ID NO：1
   693, SEQ ID NO：1695, SEQ IDNO：1697, SEQ ID NO：1
   698, SEQ ID NO：1702, およびSEQ ID NO：1703からな
   る群から選択されるアミノ酸配列もしくはその部分、ま
   たは（ｂ）（ａ）のアミノ酸配列において、数個のアミ
   ノ酸が欠失、置換または付加されたアミノ酸配列からな
   る請求項４に記載のポリペプチド。
6. 【請求項６】 請求項１に記載の核酸分子を挿入物とし
   て含むベクター。
7. 【請求項７】 前記挿入物が転写制御エレメントと作動
   的に連結している、請求項６に記載のベクター。
8. 【請求項８】 請求項７に記載のベクターで形質転換し
   た宿主細胞。
9. 【請求項９】 請求項８に記載の宿主細胞を培養するこ
   とからなる、Ｏ１５７：Ｈ７に特異的なポリペプチドの
   製造方法。
10. 【請求項１０】 （ａ）SEQ ID NO：1, SEQ ID NO：13
    2, SEQ ID NO：244,SEQ ID NO：337, SEQ ID NO：410,
    SEQ ID NO：484, SEQ ID NO：554, SEQ ID NO：630, SE
    Q ID NO：689, SEQ ID NO：755, SEQ ID NO：816, SEQ
    ID NO：876,SEQ ID NO：927, SEQ ID NO：978, SEQ ID
    NO：1013, SEQ ID NO：1029, SEQ IDNO：1055, SEQ ID
    NO：1060, SEQ ID NO：1093, SEQ ID NO：1128, SEQ ID
    NO：1157, SEQ ID NO：1191, SEQ ID NO：1212, SEQ I
    D NO：1240, SEQ ID NO：1258, SEQ ID NO：1274, SEQ
    ID NO：1288, SEQ ID NO：1302, SEQ ID NO：1309,SEQ
    ID NO：1321, SEQ ID NO：1329, SEQ ID NO：1338, SEQ
    ID NO：1348, SEQID NO：1359, SEQ ID NO：1366, SEQ
    ID NO：1374, SEQ ID NO：1380, SEQ ID NO：1386, SE
    Q ID NO：1394, SEQ ID NO：1401, SEQ ID NO：1408, S
    EQ ID NO：1411, SEQ ID NO：1418, SEQ ID NO：1426,
    SEQ ID NO：1436, SEQ ID NO：1443,SEQ ID NO：1450,
    SEQ ID NO：1457, SEQ ID NO：1460, SEQ ID NO：1467,
    SEQID NO：1471, SEQ ID NO：1473, SEQ ID NO：1478,
    SEQ ID NO：1487, SEQ IDNO：1489, SEQ ID NO：1494,
    SEQ ID NO：1499, SEQ, ID NO：1501, SEQ ID NO：150
    6, SEQ ID NO：1508, SEQ ID NO：1510, SEQ ID NO：15
    11, SEQ ID NO：1516, SEQ ID NO：1520, SEQ ID NO：1
    526, SEQ ID NO：1532, SEQ ID NO：1537,SEQ ID NO：1
    540, SEQ ID NO：1545, SEQ ID NO：1547, SEQ ID NO：
    1549, SEQID NO：1551, SEQ ID NO：1553, SEQ ID NO：
    1555, SEQ ID NO：1558, SEQ ID NO：1563, SEQ ID N
    O：1566, SEQ ID NO：1569, SEQ ID NO：1571, SEQ ID
    NO：1576, SEQ ID NO：1580, SEQ ID NO：1584, SEQ ID
    NO：1587, SEQ ID NO：1591,SEQ ID NO：1594, SEQ ID
    NO：1596, SEQ ID NO：1599, SEQ ID NO：1601, SEQID
    NO：1603, SEQ ID NO：1604, SEQ ID NO：1605, SEQ I
    D NO：1607, SEQ IDNO：1612, SEQ ID NO：1615, SEQ I
    D NO：1617, SEQ ID NO：1619, SEQ ID NO：1622, SEQ
    ID NO：1624, SEQ ID NO：1626, SEQ ID NO：1627, SEQ
    ID NO：1629, SEQ ID NO：1632, SEQ ID NO：1635, SE
    Q ID NO：1636, SEQ ID NO：1637, SEQ ID NO：1639, S
    EQ ID NO：1640, SEQ ID NO：1643, SEQ ID NO：1646,
    SEQ IDNO：1649, SEQ ID NO：1652, SEQ ID NO：1655,
    SEQ ID NO：1658, SEQ ID NO：1660, SEQ ID NO：1662,
    SEQ ID NO：1664, SEQ ID NO：1666, SEQ ID NO：166
    8, SEQ ID NO：1669, SEQ ID NO：1670, SEQ ID NO：16
    72, SEQ ID NO：1673,SEQ ID NO：1675, SEQ ID NO：16
    77, SEQ ID NO：1680, SEQ ID NO：1682, SEQID NO：16
    83, SEQ ID NO：1685, SEQ ID NO：1688, SEQ ID NO：1
    690, SEQ ID NO：1691, SEQ ID NO：1694, SEQ ID NO：
    1696, SEQ ID NO：1699, SEQ ID NO：1700, SEQ ID N
    O：1701, SEQ ID NO：1704, SEQ ID NO：1705, SEQ ID
    NO：1706,SEQ ID NO：1707, SEQ ID NO：1708, SEQ ID
    NO：1709, SEQ ID NO：1710, SEQID NO：1711, SEQ ID
    NO：1712, SEQ ID NO：1713, SEQ ID NO：1715, SEQ ID
    NO：1716, SEQ ID NO：1717, SEQ ID NO：1718,, SEQ I
    D NO：1719, SEQ ID NO：1720, SEQ ID NO：1721, SEQ
    ID NO：1722, SEQ ID NO：1723, SEQ ID NO：1724, SEQ
    ID NO：1725, SEQ ID NO：1726, SEQ ID NO：1727, SE
    Q ID NO：1728,SEQ ID NO：1729, SEQ ID NO：1730, SE
    Q ID NO：1731, SEQ ID NO：1732, SEQID NO：1733, SE
    Q ID NO：1734, SEQ ID NO：1735, SEQ ID NO：1736, S
    EQ ID NO：1737, SEQ ID NO：1738, SEQ ID NO：1739,
    SEQ ID NO：1740, SEQ ID NO：1741, SEQ ID NO：1742,
    SEQ ID NO：1743, SEQ ID NO：1744, SEQ ID NO：174
    5,SEQ ID NO：1746, SEQ ID NO：1747, SEQ ID NO：174
    8, SEQ ID NO：1749, SEQID NO：1750, SEQ ID NO：175
    1, SEQ ID NO：1752, SEQ ID NO：1753, SEQ IDNO：175
    4, SEQ ID NO：1755, SEQ ID NO：1756, SEQ ID NO：17
    57, SEQ ID NO：1758, SEQ ID NO：1759, SEQ ID NO：1
    760, SEQ ID NO：1761, SEQ ID NO：1762, SEQ ID NO：
    1763, SEQ ID NO：1764, SEQ ID NO：1765, SEQ ID N
    O：1766, SEQ ID NO：1767, SEQ ID NO：1768, SEQ ID
    NO：1769, SEQ ID NO：1770, SEQ IDNO：1771, SEQ ID
    NO：1772, SEQ ID NO：1773, SEQ ID NO：1774, SEQ ID
    NO：1775, SEQ ID NO：1776, SEQ ID NO：1777, SEQ I
    D NO：1778, SEQ ID NO：1779, SEQ ID NO：1780, SEQ
    ID NO：1781, SEQ ID NO：1782, SEQ ID NO：1783,SEQ
    ID NO：1784, SEQ ID NO：1785, SEQ ID NO：1786, SEQ
    ID NO：1787, SEQID NO：1788, SEQ ID NO：1789, SEQ
    ID NO：1790, SEQ ID NO：1791, SEQ ID NO：1792, SE
    Q ID NO：1793, SEQ ID NO：1794, SEQ ID NO：1795, S
    EQ ID NO：1796, SEQ ID NO：1797, SEQ ID NO：1798,
    SEQ ID NO：1799, SEQ ID NO：1800,SEQ ID NO：1801,
    SEQ ID NO：1802, SEQ ID NO：1803, SEQ ID NO：1804,
    SEQID NO：1805, SEQ ID NO：1806, SEQ ID NO：1807,
    SEQ ID NO：1808, SEQ IDNO：1809, SEQ ID NO：1810,
    SEQ ID NO：1811, SEQ ID NO：1812, SEQ ID NO：181
    3, SEQ ID NO：1814, SEQ ID NO：1815, SEQ ID NO：18
    16, SEQ ID NO：1817, SEQ ID NO：1818, SEQ ID NO：1
    819, SEQ ID NO：1820, SEQ ID NO：1821, SEQ ID NO：
    1822, SEQ ID NO：1823, SEQ ID NO：1824, SEQ ID N
    O：1825, SEQ IDNO：1826, SEQ ID NO：1827, SEQ ID N
    O：1828, SEQ ID NO：1829, SEQ ID NO：1830, SEQ ID
    NO：1831, SEQ ID NO：1832, SEQ ID NO：1833, SEQ ID
    NO：1834, SEQ ID NO：1835, SEQ ID NO：1836, SEQ I
    D NO：1837, SEQ ID NO：1838,SEQ ID NO：1839, SEQ I
    D NO：1840, SEQ ID NO：1841, SEQ ID NO：1842, SEQI
    D NO：1843, SEQ ID NO：1844, SEQ ID NO：1845, SEQ
    ID NO：1846, SEQ ID NO：1847, SEQ ID NO：1848, SEQ
    ID NO：1849, SEQ ID NO：1850, SEQ ID NO：1851, SE
    Q ID NO：1852, SEQ ID NO：1853, SEQ ID NO：1854, S
    EQ ID NO：1855,SEQ ID NO：1856, SEQ ID NO：1857, S
    EQ ID NO：1858, SEQ ID NO：1859, SEQID NO：1860, S
    EQ ID NO：1861, SEQ ID NO：1862, SEQ ID NO：1863,
    SEQ IDNO：1864, SEQ ID NO：1865, およびSEQ ID NO：
    1866からなる群から選択されるヌクレオチド配列、およ
    び／または（ｂ）（ａ）に記載のヌクレオチド配列と相
    補的なヌクレオチド配列の少なくとも８ヌクレオチドか
    ら構成されるヌクレオチド配列からなる、腸管出血性病
    原性大腸菌Ｏ１５７：Ｈ７に特異的なオリゴまたはポリ
    ヌクレオチド。
11. 【請求項１１】 ハイブリダイゼーション用プローブま
    たはＰＣＲ用プライマーとして用いる、請求項１０に記
    載のオリゴまたはポリヌクレオチドの使用。
12. 【請求項１２】 Ｏ１５７感染の検出または診断のため
    の請求項１１に記載のオリゴまたはポリヌクレオチドの
    使用。
13. 【請求項１３】 請求項１に記載の核酸分子もしくはそ
    のフラグメント、または請求項１０に記載のオリゴもし
    くはポリヌクレオチド、および医薬的に許容される担体
    からなるワクチン組成物。
14. 【請求項１４】 請求項４に記載のポリペプチドまたは
    そのフラグメント、および医薬的に許容される担体から
    なるワクチン組成物。
15. 【請求項１５】 請求項４に記載のポリペプチドを特異
    的に認識する抗体分子。
16. 【請求項１６】 請求項１に記載の核酸分子および／ま
    たは請求項１０に記載のオリゴまたはポリヌクレオチド
    の少なくとも１つを含むDNAマイクロアレイまたはチッ
    プ。
17. 【請求項１７】 Ｏ１５７感染の検出またはＯ１５７の
    型別のための、DNAマイクロアレイまたはチップの使
    用。
18. 【請求項１８】 請求項１に記載の核酸分子もしくはそ
    のフラグメント、または請求項４に記載のポリペプチド
    もしくはそのフラグメントを用いる、Ｏ１５７感染およ
    びこれにより引き起こされる病態の予防および／または
    治療に有用な化合物のスクリーニング方法。