GB812366A
(en)
|
1955-08-18 |
1959-04-22 |
Wellcome Found |
Improvements in and relating to derivatives of pyrimidine and the preparation thereof
|
GB937725A
(en)
|
1960-05-11 |
1963-09-25 |
Ciba Ltd |
Pyrazolo[3:4-d]pyrimidines
|
JPS4834699B1
(zh)
|
1968-07-03 |
1973-10-23 |
|
|
US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
US3657744A
(en)
|
1970-05-08 |
1972-04-25 |
Univ Minnesota |
Method for fixing prosthetic implants in a living body
|
DE2139107A1
(de)
|
1971-08-04 |
1973-02-15 |
Merck Patent Gmbh |
Heterocyclisch substituierte adenosinverbindungen
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
US3939161A
(en)
|
1973-10-29 |
1976-02-17 |
Abbott Laboratories |
1,3-Dimethyl- 1H-pyrazolo(4,3-D) pyrimidine-7 (6H)-ones
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
IT1153216B
(it)
|
1981-10-16 |
1987-01-14 |
Schering Ag |
Procedimento per la preparazione di composti cianoeterociclici
|
DE3244594A1
(de)
*
|
1982-12-02 |
1984-06-07 |
Hoechst Ag, 6230 Frankfurt |
1-phenylisochinolinderivate und verfahren zu ihrer herstellung, diese verbindung enthaltende pharmazeutische praeparate und deren anwendung
|
DE3406533A1
(de)
|
1984-02-23 |
1985-08-29 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
|
US5310731A
(en)
|
1984-06-28 |
1994-05-10 |
Whitby Research, Inc. |
N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
|
HU196714B
(en)
|
1984-10-04 |
1989-01-30 |
Monsanto Co |
Process for producing non-aqueous composition comprising somatotropin
|
US4795627A
(en)
|
1984-10-18 |
1989-01-03 |
University Of Pittsburgh |
Tritium labelled N-mustard type compounds and a process for their production
|
IE58110B1
(en)
|
1984-10-30 |
1993-07-14 |
Elan Corp Plc |
Controlled release powder and process for its preparation
|
US4656159A
(en)
|
1984-10-31 |
1987-04-07 |
Georgetown University |
Galactose-C-6 nitrogen mustard compounds and their uses
|
JPS61109797A
(ja)
|
1984-11-01 |
1986-05-28 |
Yuki Gosei Yakuhin Kogyo Kk |
標識化ヌクレオチドおよび標識化ポリヌクレオチド
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
US4733665C2
(en)
|
1985-11-07 |
2002-01-29 |
Expandable Grafts Partnership |
Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
|
US5023252A
(en)
|
1985-12-04 |
1991-06-11 |
Conrex Pharmaceutical Corporation |
Transdermal and trans-membrane delivery of drugs
|
US5350395A
(en)
|
1986-04-15 |
1994-09-27 |
Yock Paul G |
Angioplasty apparatus facilitating rapid exchanges
|
US5040548A
(en)
|
1989-06-01 |
1991-08-20 |
Yock Paul G |
Angioplasty mehtod
|
US5061273A
(en)
|
1989-06-01 |
1991-10-29 |
Yock Paul G |
Angioplasty apparatus facilitating rapid exchanges
|
CA1283827C
(en)
|
1986-12-18 |
1991-05-07 |
Giorgio Cirelli |
Appliance for injection of liquid formulations
|
US4748982A
(en)
|
1987-01-06 |
1988-06-07 |
Advanced Cardiovascular Systems, Inc. |
Reinforced balloon dilatation catheter with slitted exchange sleeve and method
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
US5001139A
(en)
|
1987-06-12 |
1991-03-19 |
American Cyanamid Company |
Enchancers for the transdermal flux of nivadipine
|
US4992445A
(en)
|
1987-06-12 |
1991-02-12 |
American Cyanamid Co. |
Transdermal delivery of pharmaceuticals
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
US5073543A
(en)
|
1988-07-21 |
1991-12-17 |
G. D. Searle & Co. |
Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
|
WO1990003370A1
(en)
|
1988-09-28 |
1990-04-05 |
Microprobe Corporation |
DERIVATIVES OF PYRAZOLO[3,4-d]PYRIMIDINE
|
CA1322628C
(en)
|
1988-10-04 |
1993-10-05 |
Richard A. Schatz |
Expandable intraluminal graft
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
GB8827305D0
(en)
|
1988-11-23 |
1988-12-29 |
British Bio Technology |
Compounds
|
IT1229203B
(it)
|
1989-03-22 |
1991-07-25 |
Bioresearch Spa |
Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
|
PH30995A
(en)
|
1989-07-07 |
1997-12-23 |
Novartis Inc |
Sustained release formulations of water soluble peptides.
|
US5442039A
(en)
|
1989-07-17 |
1995-08-15 |
The Dow Chemical Company |
Mesogenic polycyanates and thermosets thereof
|
US5428125A
(en)
|
1989-07-17 |
1995-06-27 |
The Dow Chemical Company |
Mesogenic polycyanates and thermosets thereof
|
US6344053B1
(en)
|
1993-12-22 |
2002-02-05 |
Medtronic Ave, Inc. |
Endovascular support device and method
|
US5292331A
(en)
|
1989-08-24 |
1994-03-08 |
Applied Vascular Engineering, Inc. |
Endovascular support device
|
US5674278A
(en)
|
1989-08-24 |
1997-10-07 |
Arterial Vascular Engineering, Inc. |
Endovascular support device
|
US5763597A
(en)
|
1989-09-15 |
1998-06-09 |
Metabasis Therapeutics, Inc. |
Orally active adenosine kinase inhibitors
|
US5721356A
(en)
|
1989-09-15 |
1998-02-24 |
Gensia, Inc. |
Orally active adenosine kinase inhibitors
|
US5646128A
(en)
|
1989-09-15 |
1997-07-08 |
Gensia, Inc. |
Methods for treating adenosine kinase related conditions
|
US5795977A
(en)
|
1989-09-15 |
1998-08-18 |
Metabasis Therapeutics, Inc. |
Water soluble adenosine kinase inhibitors
|
US5674998A
(en)
|
1989-09-15 |
1997-10-07 |
Gensia Inc. |
C-4' modified adenosine kinase inhibitors
|
US5763596A
(en)
|
1989-09-15 |
1998-06-09 |
Metabasis Therapeutics, Inc. |
C-4' modified adenosine kinase inhibitors
|
US5120548A
(en)
|
1989-11-07 |
1992-06-09 |
Merck & Co., Inc. |
Swelling modulated polymeric drug delivery device
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
WO1991009594A1
(en)
|
1989-12-28 |
1991-07-11 |
Virginia Commonwealth University |
Sigma receptor ligands and the use thereof
|
JPH04211063A
(ja)
|
1990-03-05 |
1992-08-03 |
Takeda Chem Ind Ltd |
縮合三環性複素環化合物、その製造法、用途及び中間体
|
GB9009542D0
(en)
|
1990-04-27 |
1990-06-20 |
Beecham Group Plc |
Novel compounds
|
US5733566A
(en)
|
1990-05-15 |
1998-03-31 |
Alkermes Controlled Therapeutics Inc. Ii |
Controlled release of antiparasitic agents in animals
|
GB9113137D0
(en)
|
1990-07-13 |
1991-08-07 |
Ici Plc |
Thioxo heterocycles
|
US5563257A
(en)
|
1990-08-20 |
1996-10-08 |
Boehringer Mannheim Gmbh |
Phospholipid derivatives of nucleosides
|
DE4026265A1
(de)
|
1990-08-20 |
1992-02-27 |
Boehringer Mannheim Gmbh |
Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
US5561134A
(en)
|
1990-09-25 |
1996-10-01 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
|
US5652366A
(en)
|
1990-09-25 |
1997-07-29 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
DI (1R)-(-)camphosulfonic acid) salt, preparation thereof and use thereof
|
AU654507B2
(en)
|
1990-09-25 |
1994-11-10 |
Rhone-Poulenc Rorer International (Holdings) Inc. |
Compounds having antihypertensive and anti-ischemic properties
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
GB9103839D0
(en)
|
1991-02-23 |
1991-04-10 |
Smithkline Beecham Plc |
Pharmaceuticals
|
WO1992020642A1
(en)
|
1991-05-10 |
1992-11-26 |
Rhone-Poulenc Rorer International (Holdings) Inc. |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase
|
US5710158A
(en)
|
1991-05-10 |
1998-01-20 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
USRE37650E1
(en)
|
1991-05-10 |
2002-04-09 |
Aventis Pharmacetical Products, Inc. |
Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
|
US5480883A
(en)
|
1991-05-10 |
1996-01-02 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
US5721237A
(en)
|
1991-05-10 |
1998-02-24 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties
|
US5714493A
(en)
|
1991-05-10 |
1998-02-03 |
Rhone-Poulenc Rorer Pharmaceuticals, Inc. |
Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
|
US6645969B1
(en)
|
1991-05-10 |
2003-11-11 |
Aventis Pharmaceuticals Inc. |
Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
US5580578A
(en)
|
1992-01-27 |
1996-12-03 |
Euro-Celtique, S.A. |
Controlled release formulations coated with aqueous dispersions of acrylic polymers
|
IL104369A0
(en)
|
1992-01-13 |
1993-05-13 |
Smithkline Beecham Corp |
Novel compounds and compositions
|
US5916891A
(en)
|
1992-01-13 |
1999-06-29 |
Smithkline Beecham Corporation |
Pyrimidinyl imidazoles
|
DE4204031A1
(de)
|
1992-02-12 |
1993-08-19 |
Boehringer Mannheim Gmbh |
Neue lipidphosphonsaeure-nucleosid-konjugate sowie deren verwendung als antivirale arzneimittel
|
DE4204032A1
(de)
|
1992-02-12 |
1993-08-19 |
Boehringer Mannheim Gmbh |
Neue liponucleotide, deren herstellunmg sowie deren verwendung als antivirale arzneimittel
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
WO1993018035A1
(en)
|
1992-03-04 |
1993-09-16 |
Abbott Laboratories |
Angiotensin ii receptor antagonists
|
JP2737518B2
(ja)
|
1992-03-16 |
1998-04-08 |
富士通株式会社 |
赤外線検知器の冷却構造
|
US5294612A
(en)
|
1992-03-30 |
1994-03-15 |
Sterling Winthrop Inc. |
6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof
|
AU684461B2
(en)
|
1992-04-07 |
1997-12-18 |
Regents Of The University Of Michigan, The |
CD28 pathway immunoregulation
|
GB9208135D0
(en)
|
1992-04-13 |
1992-05-27 |
Ludwig Inst Cancer Res |
Polypeptides having kinase activity,their preparation and use
|
EP0672159B1
(en)
|
1992-04-24 |
2005-12-28 |
Sri International |
Homologous sequence targeting in eukaryotic cells
|
CA2117476C
(en)
|
1992-06-19 |
2000-02-22 |
R. Andrew Wood |
Infrared camera with thermoelectric temperature stabilization
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
US6057305A
(en)
|
1992-08-05 |
2000-05-02 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
Antiretroviral enantiomeric nucleotide analogs
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
TW333456B
(en)
|
1992-12-07 |
1998-06-11 |
Takeda Pharm Ind Co Ltd |
A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
|
TW444018B
(en)
|
1992-12-17 |
2001-07-01 |
Pfizer |
Pyrazolopyrimidines
|
US5455258A
(en)
|
1993-01-06 |
1995-10-03 |
Ciba-Geigy Corporation |
Arylsulfonamido-substituted hydroxamic acids
|
US5591767A
(en)
|
1993-01-25 |
1997-01-07 |
Pharmetrix Corporation |
Liquid reservoir transdermal patch for the administration of ketorolac
|
IL108523A0
(en)
|
1993-02-03 |
1994-05-30 |
Gensia Inc |
Pharmaceutical compositions containing adenosine kinase inhibitors for preventing or treating conditions involving inflammatory responses and pain
|
JPH08506343A
(ja)
|
1993-02-03 |
1996-07-09 |
ジェンシア・インコーポレイテッド |
リキソフラノシル誘導体を含むアデノシンキナーゼ阻害物質
|
GB9308957D0
(en)
|
1993-04-30 |
1993-06-16 |
Cancer Res Campaign Tech |
Novel produgs
|
EP0700430B1
(en)
|
1993-06-04 |
2005-04-20 |
The United States of America as Represented by the Secretary of the Navy |
Methods for selectively stimulating proliferation of t cells
|
US6087324A
(en)
|
1993-06-24 |
2000-07-11 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation
|
US5504103A
(en)
|
1993-08-25 |
1996-04-02 |
Eli Lilly And Company |
Inhibition of phosphatidylinositol 3-kinase with 17 β-hydroxywortmannin and analogs thereof
|
US5525503A
(en)
*
|
1993-09-28 |
1996-06-11 |
Dana-Farber Cancer Institute, Inc. |
Signal transduction via CD28
|
WO1995012588A1
(en)
|
1993-11-05 |
1995-05-11 |
Biochem Pharma Inc. |
Antineoplastic heteronaphthoquinones
|
US5656643A
(en)
|
1993-11-08 |
1997-08-12 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
IL112249A
(en)
|
1994-01-25 |
2001-11-25 |
Warner Lambert Co |
Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
|
US5654307A
(en)
|
1994-01-25 |
1997-08-05 |
Warner-Lambert Company |
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
US6632789B1
(en)
|
1994-04-29 |
2003-10-14 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for modulating T cell responses by manipulating intracellular signal transduction
|
DE4418690A1
(de)
|
1994-05-28 |
1996-01-11 |
Boehringer Mannheim Gmbh |
Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel
|
IT1270594B
(it)
|
1994-07-07 |
1997-05-07 |
Recordati Chem Pharm |
Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
|
US6323201B1
(en)
|
1994-12-29 |
2001-11-27 |
The Regents Of The University Of California |
Compounds for inhibition of ceramide-mediated signal transduction
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
US5863949A
(en)
|
1995-03-08 |
1999-01-26 |
Pfizer Inc |
Arylsulfonylamino hydroxamic acid derivatives
|
US6312894B1
(en)
|
1995-04-03 |
2001-11-06 |
Epoch Pharmaceuticals, Inc. |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
|
AU711592B2
(en)
|
1995-04-03 |
1999-10-14 |
Novartis Ag |
Pyrazole derivatives and processes for the preparation thereof
|
DE69519751T2
(de)
|
1995-04-20 |
2001-04-19 |
Pfizer |
Arylsulfonamido-substituierte hydroxamsäure derivate als inhibitoren von mmp und tnf
|
US5977061A
(en)
|
1995-04-21 |
1999-11-02 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
N6 - substituted nucleotide analagues and their use
|
JPH08295667A
(ja)
|
1995-04-27 |
1996-11-12 |
Takeda Chem Ind Ltd |
複素環化合物、その製造法および剤
|
WO1996037777A1
(en)
|
1995-05-23 |
1996-11-28 |
Nelson Randall W |
Mass spectrometric immunoassay
|
US5593997A
(en)
|
1995-05-23 |
1997-01-14 |
Pfizer Inc. |
4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
US6403599B1
(en)
|
1995-11-08 |
2002-06-11 |
Pfizer Inc |
Corticotropin releasing factor antagonists
|
AU5982296A
(en)
|
1995-06-07 |
1996-12-30 |
G.D. Searle & Co. |
Method to treat cardiofibrosis with a combination of an angi otensin ii antagonist and spironolactone
|
US5665721A
(en)
|
1995-06-07 |
1997-09-09 |
Abbott Laboratories |
Heterocyclic substituted cyclopentane compounds
|
PL185150B1
(pl)
|
1995-06-07 |
2003-03-31 |
Searle & Co |
Kompozycja farmaceutyczna do leczenia zaburzeń sercowo-naczyniowych
|
EP0831911B1
(en)
|
1995-06-07 |
2002-04-17 |
G.D. Searle & Co. |
Spironolactone and angiotensin ii antagonist combination therapy for treatment of congestive heart failure
|
EP0835101B1
(en)
|
1995-06-27 |
2004-06-09 |
Takeda Chemical Industries, Ltd. |
Method of producing sustained-release preparation
|
TW448055B
(en)
|
1995-09-04 |
2001-08-01 |
Takeda Chemical Industries Ltd |
Method of production of sustained-release preparation
|
JP2909418B2
(ja)
|
1995-09-18 |
1999-06-23 |
株式会社資生堂 |
薬物の遅延放出型マイクロスフイア
|
US5763885A
(en)
|
1995-12-19 |
1998-06-09 |
Loral Infrared & Imaging Systems, Inc. |
Method and apparatus for thermal gradient stabilization of microbolometer focal plane arrays
|
JPH09143163A
(ja)
|
1995-11-29 |
1997-06-03 |
Fuji Photo Film Co Ltd |
含窒素ヘテロ芳香族アミド類の製造方法
|
ATE225343T1
(de)
|
1995-12-20 |
2002-10-15 |
Hoffmann La Roche |
Matrix-metalloprotease inhibitoren
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
US5980945A
(en)
|
1996-01-16 |
1999-11-09 |
Societe De Conseils De Recherches Et D'applications Scientifique S.A. |
Sustained release drug formulations
|
US5747235A
(en)
|
1996-01-26 |
1998-05-05 |
Eastman Kodak Company |
Silver halide light sensitive emulsion layer having enhanced photographic sensitivity
|
CH690773A5
(de)
|
1996-02-01 |
2001-01-15 |
Novartis Ag |
Pyrrolo(2,3-d)pyrimide und ihre Verwendung.
|
DE19603576A1
(de)
|
1996-02-01 |
1997-08-07 |
Bayer Ag |
Acylierte 4-Amino und 4-Hydrazinopyrimidine
|
GB2310952B
(en)
|
1996-03-05 |
1998-08-19 |
Mitsubishi Electric Corp |
Infrared detector
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
PT807633E
(pt)
|
1996-05-15 |
2003-02-28 |
Pfizer |
Novas pirimidin-4-onas substituidas em 2,3, e fundidas com heteroarilo em (5,6)
|
GB9611460D0
(en)
|
1996-06-01 |
1996-08-07 |
Ludwig Inst Cancer Res |
Novel lipid kinase
|
CA2258822A1
(en)
|
1996-06-20 |
1997-12-24 |
Sean Kerwin |
Compounds and methods for providing pharmacologically active preparations and uses thereof
|
US6264970B1
(en)
|
1996-06-26 |
2001-07-24 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation
|
EP0818442A3
(en)
|
1996-07-12 |
1998-12-30 |
Pfizer Inc. |
Cyclic sulphone derivatives as inhibitors of metalloproteinases and of the production of tumour necrosis factor
|
WO1998003516A1
(en)
|
1996-07-18 |
1998-01-29 |
Pfizer Inc. |
Phosphinate based inhibitors of matrix metalloproteases
|
SK21499A3
(en)
|
1996-08-23 |
2000-05-16 |
Pfizer |
Arylsulfonylamino hydroxamic acid derivatives
|
US6419961B1
(en)
|
1996-08-29 |
2002-07-16 |
Takeda Chemical Industries, Ltd. |
Sustained release microcapsules of a bioactive substance and a biodegradable polymer
|
CA2217134A1
(en)
|
1996-10-09 |
1998-04-09 |
Sumitomo Pharmaceuticals Co., Ltd. |
Sustained release formulation
|
US5994358A
(en)
|
1996-10-23 |
1999-11-30 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
US6342514B1
(en)
|
1996-10-23 |
2002-01-29 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
US5965573A
(en)
|
1996-10-23 |
1999-10-12 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
US5919808A
(en)
|
1996-10-23 |
1999-07-06 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
US5990169A
(en)
|
1996-10-23 |
1999-11-23 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
US6251901B1
(en)
|
1996-10-23 |
2001-06-26 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
US5948776A
(en)
|
1996-10-23 |
1999-09-07 |
Zymogenetic, Inc. |
Compositions and methods for treating bone deficit conditions
|
US5922753A
(en)
|
1996-10-23 |
1999-07-13 |
Zymogenetics, Inc. |
Methods for treating bone deficit conditions with benzothiazole
|
US6153631A
(en)
|
1996-10-23 |
2000-11-28 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
PT839525E
(pt)
|
1996-10-31 |
2004-10-29 |
Takeda Chemical Industries Ltd |
Preparacao de libertacao prolongada
|
US5858753A
(en)
|
1996-11-25 |
1999-01-12 |
Icos Corporation |
Lipid kinase
|
WO1998024804A2
(en)
|
1996-12-06 |
1998-06-11 |
Vertex Pharmaceuticals Incorporated |
INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME
|
US6197350B1
(en)
|
1996-12-20 |
2001-03-06 |
Takeda Chemical Industries, Ltd. |
Method of producing a sustained-release preparation
|
US6093737A
(en)
|
1996-12-30 |
2000-07-25 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
PT950059E
(pt)
|
1997-01-06 |
2004-10-29 |
Pfizer |
Derivados de sulfona ciclicos
|
JPH10206995A
(ja)
|
1997-01-21 |
1998-08-07 |
Konica Corp |
ハロゲン化銀写真感光材料
|
US5891474A
(en)
|
1997-01-29 |
1999-04-06 |
Poli Industria Chimica, S.P.A. |
Time-specific controlled release dosage formulations and method of preparing same
|
EP0977733B1
(en)
|
1997-02-03 |
2003-09-03 |
Pfizer Products Inc. |
Arylsulfonylamino hydroxamic acid derivatives
|
CA2279863A1
(en)
|
1997-02-07 |
1998-08-13 |
Pfizer Inc. |
N-hydroxy-beta-sulfonyl-propionamide derivatives and their use as inhibitors of matrix metalloproteinases
|
WO1998035048A2
(en)
|
1997-02-07 |
1998-08-13 |
Princeton University |
Engineered protein kinases which can utilize modified nucleotide triphosphate substrates
|
CN1247531A
(zh)
|
1997-02-11 |
2000-03-15 |
辉瑞大药厂 |
芳基磺酰基异羟肟酸衍生物
|
US7863444B2
(en)
|
1997-03-19 |
2011-01-04 |
Abbott Laboratories |
4-aminopyrrolopyrimidines as kinase inhibitors
|
ATE242245T1
(de)
|
1997-03-19 |
2003-06-15 |
Basf Ag |
Pyrrolo(2,3-d)pyrimidine und ihre verwendung als tyrosinkinase-inhibitoren
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
AU7449598A
(en)
|
1997-05-23 |
1998-12-11 |
Nippon Shinyaku Co. Ltd. |
Medicinal composition for prevention or treatment of hepatopathy
|
US6207679B1
(en)
|
1997-06-19 |
2001-03-27 |
Sepracor, Inc. |
Antimicrobial agents uses and compositions related thereto
|
ID23668A
(id)
|
1997-08-08 |
2000-05-11 |
Pfizer Prod Inc |
Turunan asam ariloksiarilsulfonilamino hidroksamat
|
EP1020445B1
(en)
|
1997-10-02 |
2008-08-13 |
Eisai R&D Management Co., Ltd. |
Fused pyridine derivatives
|
US6649631B1
(en)
|
1997-10-23 |
2003-11-18 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for treating bone deficit conditions
|
CN1130363C
(zh)
|
1997-11-12 |
2003-12-10 |
三菱化学株式会社 |
嘌呤衍生物以及含有其作为有效成分的药物
|
GB9725782D0
(en)
|
1997-12-05 |
1998-02-04 |
Pfizer Ltd |
Therapeutic agents
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
US6191170B1
(en)
|
1998-01-13 |
2001-02-20 |
Tularik Inc. |
Benzenesulfonamides and benzamides as therapeutic agents
|
GB9801690D0
(en)
|
1998-01-27 |
1998-03-25 |
Pfizer Ltd |
Therapeutic agents
|
WO1999045009A1
(en)
|
1998-03-04 |
1999-09-10 |
Bristol-Myers Squibb Company |
Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors
|
US6613358B2
(en)
|
1998-03-18 |
2003-09-02 |
Theodore W. Randolph |
Sustained-release composition including amorphous polymer
|
JP4462654B2
(ja)
|
1998-03-26 |
2010-05-12 |
ソニー株式会社 |
映像素材選択装置及び映像素材選択方法
|
US7715989B2
(en)
|
1998-04-03 |
2010-05-11 |
Elitech Holding B.V. |
Systems and methods for predicting oligonucleotide melting temperature (TmS)
|
US6127121A
(en)
|
1998-04-03 |
2000-10-03 |
Epoch Pharmaceuticals, Inc. |
Oligonucleotides containing pyrazolo[3,4-D]pyrimidines for hybridization and mismatch discrimination
|
US6432970B2
(en)
|
1998-04-09 |
2002-08-13 |
Johns Hopkins University School Of Medicine |
Inhibitors of hedgehog signaling pathways, compositions and uses related thereto
|
PA8469401A1
(es)
|
1998-04-10 |
2000-05-24 |
Pfizer Prod Inc |
Derivados biciclicos del acido hidroxamico
|
PA8469501A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico
|
KR19990085365A
(ko)
|
1998-05-16 |
1999-12-06 |
허영섭 |
지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법
|
JP2000072773A
(ja)
|
1998-08-28 |
2000-03-07 |
Zeria Pharmaceut Co Ltd |
プリン誘導体
|
CZ2001959A3
(cs)
|
1998-09-18 |
2001-12-12 |
Basf Aktiengesellschaft |
4-Aminopyrrolopyrimidiny jako inhibitory kinasy
|
US6362216B1
(en)
|
1998-10-27 |
2002-03-26 |
Array Biopharma Inc. |
Compounds which inhibit tryptase activity
|
US6114361A
(en)
|
1998-11-05 |
2000-09-05 |
Pfizer Inc. |
5-oxo-pyrrolidine-2-carboxylic acid hydroxamide derivatives
|
EP1140938B1
(en)
|
1999-01-11 |
2003-08-27 |
Princeton University |
High affinity inhibitors for target validation and uses thereof
|
CZ27399A3
(cs)
|
1999-01-26 |
2000-08-16 |
Ústav Experimentální Botaniky Av Čr |
Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
|
CA2360934A1
(en)
|
1999-02-22 |
2000-08-31 |
Lin-Hua Zhang |
Polycyclo heterocyclic derivatives as antiinflammatory agents
|
US6248363B1
(en)
|
1999-11-23 |
2001-06-19 |
Lipocine, Inc. |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
NZ514711A
(en)
|
1999-03-12 |
2004-02-27 |
Boehringer Ingelheim Pharma |
Compounds useful as anti-inflammatory agents
|
EP1040831A3
(en)
|
1999-04-02 |
2003-05-02 |
Pfizer Products Inc. |
Use of corticotropin releasing factor (CRF) antagonists to prevent sudden death
|
SE515856C2
(sv)
|
1999-05-19 |
2001-10-22 |
Ericsson Telefon Ab L M |
Bärare för elektronikkomponenter
|
KR20020062808A
(ko)
|
1999-06-03 |
2002-07-31 |
크놀 게엠베하 |
벤조티아지논 및 벤족사지논 화합물
|
US6387894B1
(en)
|
1999-06-11 |
2002-05-14 |
Pfizer Inc. |
Use of CRF antagonists and renin-angiotensin system inhibitors
|
TWI262914B
(en)
|
1999-07-02 |
2006-10-01 |
Agouron Pharma |
Compounds and pharmaceutical compositions for inhibiting protein kinases
|
PE20010306A1
(es)
|
1999-07-02 |
2001-03-29 |
Agouron Pharma |
Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa
|
EP1081137A1
(en)
|
1999-08-12 |
2001-03-07 |
Pfizer Products Inc. |
Selective inhibitors of aggrecanase in osteoarthritis treatment
|
GB9919588D0
(en)
|
1999-08-18 |
1999-10-20 |
Hoechst Schering Agrevo Gmbh |
Fungicidal compounds
|
JP4831906B2
(ja)
|
1999-08-27 |
2011-12-07 |
ケモセントリックス, インコーポレイテッド |
Cxcr3機能を調節するための複素環式化合物および方法
|
US20070021493A1
(en)
|
1999-09-16 |
2007-01-25 |
Curis, Inc. |
Mediators of hedgehog signaling pathways, compositions and uses related thereto
|
ATE286033T1
(de)
|
1999-09-16 |
2005-01-15 |
Curis Inc |
Vermittler von igel signalwegen, deren zusammenstellungen und verwendungen
|
US6921763B2
(en)
|
1999-09-17 |
2005-07-26 |
Abbott Laboratories |
Pyrazolopyrimidines as therapeutic agents
|
CA2385747A1
(en)
|
1999-09-17 |
2001-03-22 |
Gavin C. Hirst |
Pyrazolopyrimidines as therapeutic agents
|
WO2001021160A2
(en)
|
1999-09-23 |
2001-03-29 |
Axxima Pharmaceuticals Aktiengesellschaft |
Carboxymide and aniline derivatives as selective inhibitors of pathogens
|
JP5036112B2
(ja)
|
1999-10-06 |
2012-09-26 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
チロシンキナーゼのインヒビターとして有益な複素環化合物
|
US6506769B2
(en)
|
1999-10-06 |
2003-01-14 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Heterocyclic compounds useful as inhibitors of tyrosine kinases
|
AU7683500A
(en)
|
1999-10-12 |
2001-04-23 |
Takeda Chemical Industries Ltd. |
Pyrimidine-5-carboxamide compounds, process for producing the same and use thereof
|
WO2001027135A2
(en)
|
1999-10-13 |
2001-04-19 |
Johns Hopkins University School Of Medicine |
Regulators of the hedgehog pathway, compositions and uses related thereto
|
CA2286451A1
(en)
|
1999-10-14 |
2001-04-14 |
Grant A. Mitchell |
Hormone-sensitive lipase mediated male infertility
|
US6472153B1
(en)
|
1999-10-26 |
2002-10-29 |
Epoch Biosciences, Inc. |
Hybridization-triggered fluorescent detection of nucleic acids
|
EP1095933A1
(en)
|
1999-10-30 |
2001-05-02 |
Aventis Pharma Deutschland GmbH |
Novel N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them
|
US6660845B1
(en)
|
1999-11-23 |
2003-12-09 |
Epoch Biosciences, Inc. |
Non-aggregating, non-quenching oligomers comprising nucleotide analogues; methods of synthesis and use thereof
|
IL133809A0
(en)
|
1999-12-30 |
2001-04-30 |
Yeda Res & Dev |
Steroidal alkaloids and pharmaceutical compositions comprising them
|
GB0002032D0
(en)
|
2000-01-28 |
2000-03-22 |
Zeneca Ltd |
Chemical compounds
|
US7217722B2
(en)
|
2000-02-01 |
2007-05-15 |
Kirin Beer Kabushiki Kaisha |
Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
|
FR2804958B1
(fr)
|
2000-02-15 |
2005-07-08 |
Hoechst Marion Roussel Inc |
Derives de xanthine, leur procede de preparation et les intermediaires de ce procede, leur application comme medicament et les compositions pharmaceutiques les renfermant
|
US7115653B2
(en)
|
2000-03-30 |
2006-10-03 |
Curis, Inc. |
Small organic molecule regulators of cell proliferation
|
DK1272168T3
(da)
|
2000-03-30 |
2006-02-13 |
Curis Inc |
Sma organiske molekyler som celleproliferationsregulatorer
|
US6613798B1
(en)
|
2000-03-30 |
2003-09-02 |
Curis, Inc. |
Small organic molecule regulators of cell proliferation
|
US20020127625A1
(en)
|
2000-03-31 |
2002-09-12 |
Forskarpatent Is Syd Ab |
Methods of diagnosing immune related diseases
|
KR100785363B1
(ko)
|
2000-04-25 |
2007-12-18 |
이코스 코포레이션 |
인간 포스파티딜-이노시톨 3-키나제 델타의 억제제
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
US6777439B2
(en)
|
2000-05-30 |
2004-08-17 |
Advanced Research & Technology Institute, Inc. |
Compositions and methods for identifying agents which modulate PTEN function and PI-3 kinase pathways
|
US6667398B2
(en)
|
2000-06-22 |
2003-12-23 |
Pfizer Inc |
Process for the preparation of pyrazolopyrimidinones
|
WO2002000650A2
(en)
|
2000-06-27 |
2002-01-03 |
Genelabs Technologies, Inc. |
Novel compounds possessing antibacterial, antifungal or antitumor activity
|
US6534691B2
(en)
|
2000-07-18 |
2003-03-18 |
E. I. Du Pont De Nemours And Company |
Manufacturing process for α-olefins
|
WO2002028853A1
(fr)
*
|
2000-10-02 |
2002-04-11 |
Tanabe Seiyaku Co., Ltd. |
Compose de benzylamine, son procede de production et produit intermediaire correspondant
|
AU2002213467A8
(en)
|
2000-10-11 |
2009-07-30 |
Chemocentryx Inc |
Modulation of ccr4 function
|
EP1317464B1
(en)
|
2000-10-11 |
2009-05-13 |
Applera Corporation |
Fluorescent nucleobase conjugates having anionic linkers
|
FR2815346B1
(fr)
|
2000-10-13 |
2004-02-20 |
Servier Lab |
Nouveaux composes aminotriazolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
JP2002131859A
(ja)
|
2000-10-19 |
2002-05-09 |
Konica Corp |
撮影用赤外感光性ハロゲン化銀写真感光材料及び赤外感光性ハロゲン化銀乳剤
|
US6890747B2
(en)
|
2000-10-23 |
2005-05-10 |
Warner-Lambert Company |
Phosphoinositide 3-kinases
|
IL156304A0
(en)
|
2000-12-11 |
2004-01-04 |
Tularik Inc |
Cxcr3 antagonists
|
RU2290403C2
(ru)
|
2000-12-28 |
2006-12-27 |
Дайити Фармасьютикал Ко., Лтд. |
Ингибиторы vla-4
|
EP1359911A2
(en)
|
2000-12-29 |
2003-11-12 |
Alteon, Inc. |
Method for treating fibrotic diseases or other indications ivc
|
WO2002053160A1
(en)
|
2000-12-29 |
2002-07-11 |
Alteon, Inc. |
Method for treating glaucoma ivb
|
US7105499B2
(en)
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
MY134070A
(en)
|
2001-01-22 |
2007-11-30 |
Isis Pharmaceuticals Inc |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
GB0102239D0
(en)
|
2001-01-29 |
2001-03-14 |
Cancer Res Ventures Ltd |
Methods of chemical synthisis
|
PA8539401A1
(es)
|
2001-02-14 |
2002-10-28 |
Warner Lambert Co |
Quinazolinas como inhibidores de mmp-13
|
PA8539501A1
(es)
|
2001-02-14 |
2002-09-30 |
Warner Lambert Co |
Compuestos triazolo como inhibidores de mmp
|
MXPA03008560A
(es)
|
2001-03-22 |
2004-06-30 |
Abbot Gmbh & Co Kg |
Pirazolopirimidinas como agentes terapeuticos.
|
US7250569B2
(en)
|
2001-04-26 |
2007-07-31 |
New York University School Of Medicine |
Method for dissolving nanostructural materials
|
JP2004528376A
(ja)
|
2001-05-08 |
2004-09-16 |
クドス ファーマシューティカルズ リミテッド |
Parp阻害薬としてのイソキノリノン誘導体
|
IL149462A0
(en)
|
2001-05-09 |
2002-11-10 |
Warner Lambert Co |
Method of treating or inhibiting neutrophil chemotaxis by administering a mek inhibitor
|
WO2002094264A1
(en)
|
2001-05-23 |
2002-11-28 |
Tularik Inc. |
Ccr4 antagonists
|
US6777425B2
(en)
|
2001-06-13 |
2004-08-17 |
Genesoft Pharmaceuticals, Inc. |
Isoquinoline compounds having antiinfective activity
|
WO2002101007A2
(en)
|
2001-06-13 |
2002-12-19 |
Genesoft Pharmaceuticals, Inc |
Antipathogenic benzamide compounds
|
US6825228B2
(en)
|
2001-06-13 |
2004-11-30 |
Genesoft Pharmaceuticals, Inc. |
Benzothiophene compounds having antiinfective activity
|
WO2003000187A2
(en)
|
2001-06-21 |
2003-01-03 |
Ariad Pharmaceuticals, Inc. |
Novel pyrazolo-and pyrrolo-pyrimidines and uses thereof
|
DE10134721A1
(de)
|
2001-07-17 |
2003-02-06 |
Bayer Ag |
Tetrahydrochinoxaline
|
KR20040031782A
(ko)
|
2001-07-27 |
2004-04-13 |
쿠리스 인코퍼레이션 |
헤지호그 신호전달 경로의 조절물질, 이를 함유하는조성물 및 이의 용도
|
WO2003011285A1
(en)
|
2001-08-01 |
2003-02-13 |
Merck & Co., Inc. |
BENZIMIDAZO[4,5-f]ISOQUINOLINONE DERIVATIVES
|
AU2002327422A1
(en)
|
2001-08-03 |
2003-03-18 |
Abbott Laboratories |
Method of identifying inhibitors of lck
|
ATE530520T1
(de)
|
2001-08-10 |
2011-11-15 |
Shionogi & Co |
Antivirales mittel
|
JP2003073357A
(ja)
|
2001-09-03 |
2003-03-12 |
Mitsubishi Pharma Corp |
アミド化合物を含有するRhoキナーゼ阻害剤
|
EP1572072A4
(en)
|
2001-09-13 |
2009-04-01 |
Genesoft Inc |
PROCESS FOR TREATING INFECTIONS WITH PHARMACORESISTANT BACTERIA
|
US8124625B2
(en)
|
2001-09-14 |
2012-02-28 |
Shionogi & Co., Ltd. |
Method of enhancing the expression of apolipoprotein AI using olefin derivatives
|
AUPR769501A0
(en)
|
2001-09-14 |
2001-10-11 |
Biomolecular Research Institute Limited |
Cytokine receptor 1
|
US7101884B2
(en)
|
2001-09-14 |
2006-09-05 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
US7269663B2
(en)
|
2001-09-28 |
2007-09-11 |
Intel Corporation |
Tagging packets with a lookup key to facilitate usage of a unified packet forwarding cache
|
TWI330183B
(zh)
|
2001-10-22 |
2010-09-11 |
Eisai R&D Man Co Ltd |
|
AU2002363176B2
(en)
|
2001-11-01 |
2008-09-25 |
Janssen Pharmaceutica N.V. |
Heteroaryl amines as glycogen synthase kinase 3Beta inhibitors (GSK3 inhibitors)
|
IL161516A0
(en)
|
2001-11-09 |
2004-09-27 |
Boehringer Ingelheim Pharma |
Benzimidazoles useful as protein kinase inhibitors
|
DE10159269A1
(de)
|
2001-12-03 |
2003-06-18 |
Bayer Ag |
Arylierung von Olefinen
|
DE10159270A1
(de)
|
2001-12-03 |
2003-06-12 |
Bayer Ag |
Verfahren zur Arylierung von Olefinen
|
AU2002350217A1
(en)
|
2001-12-04 |
2003-06-17 |
Bristol-Myers Squibb Company |
Glycinamides as factor xa inhibitors
|
JP4085237B2
(ja)
|
2001-12-21 |
2008-05-14 |
日本電気株式会社 |
携帯電話の利用契約システムと通信方法
|
EP1465869B1
(en)
|
2001-12-21 |
2013-05-15 |
Exelixis Patent Company LLC |
Modulators of lxr
|
US7064218B2
(en)
|
2001-12-26 |
2006-06-20 |
Genelabs Technologies, Inc. |
Aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity
|
US7414036B2
(en)
|
2002-01-25 |
2008-08-19 |
Muscagen Limited |
Compounds useful as A3 adenosine receptor agonists
|
US20040043959A1
(en)
|
2002-03-04 |
2004-03-04 |
Bloom Laura A. |
Combination therapies for treating methylthioadenosine phosphorylase deficient cells
|
AU2003225933A1
(en)
|
2002-03-22 |
2003-10-13 |
Cellular Genomics, Inc. |
AN IMPROVED FORMULATION OF CERTAIN PYRAZOLO(3,4-d) PYRIMIDINES AS KINASE MODULATORS
|
JP4663986B2
(ja)
|
2002-03-26 |
2011-04-06 |
ツェントファーム・ゲーエムベーハー |
フレデリカマイシン−誘導体
|
US7166293B2
(en)
|
2002-03-29 |
2007-01-23 |
Carlsbad Technology, Inc. |
Angiogenesis inhibitors
|
DE10217046A1
(de)
|
2002-04-17 |
2003-11-06 |
Bioleads Gmbh |
Fredericamycin-Derivate
|
ATE404200T1
(de)
|
2002-04-22 |
2008-08-15 |
Univ Johns Hopkins Med |
Modulatoren von hedgehog signalpfaden, zusammensetzungen und verwandte verwendungen
|
AU2003223012A1
(en)
|
2002-04-26 |
2003-11-10 |
Pfizer Products Inc. |
Pyrimidine-2, 4, 6-trione metallo-proteinase inhibitors
|
US6794562B2
(en)
|
2002-05-01 |
2004-09-21 |
Stine Seed Farm, Inc. |
Soybean cultivar 0332143
|
CA2485343A1
(en)
|
2002-05-23 |
2004-05-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
WO2003106426A1
(en)
|
2002-06-14 |
2003-12-24 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
US7265111B2
(en)
|
2002-06-27 |
2007-09-04 |
Sanofi-Aventis Deutschland Gmbh |
Adenosine analogues and their use as pharmaceutical agents
|
EP1531815B1
(en)
|
2002-06-27 |
2014-09-24 |
Novo Nordisk A/S |
Glucokinase activators
|
RU2340605C2
(ru)
|
2002-06-27 |
2008-12-10 |
Ново Нордиск А/С |
Арилкарбонильные производные в качестве терапевтических средств
|
DE10230917A1
(de)
|
2002-07-09 |
2004-02-05 |
Bioleads Gmbh |
Fredericamycin-Derivate
|
AU2003249244A1
(en)
|
2002-07-15 |
2004-02-02 |
Combinatorx, Incorporated |
Methods for the treatment of neoplasms
|
WO2004014377A1
(en)
|
2002-08-13 |
2004-02-19 |
Warner-Lambert Company Llc |
4-hydroxyquinoline derivatives as matrix metalloproteinase inhibitors
|
EP1394159A1
(fr)
|
2002-08-13 |
2004-03-03 |
Warner-Lambert Company LLC |
Nouveaux dérivés de thiophène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
|
NZ538420A
(en)
*
|
2002-08-16 |
2007-06-29 |
Kinacia Pty Ltd |
Inhibition of phosphoinositide 3-kinase beta
|
CN100430389C
(zh)
*
|
2002-08-16 |
2008-11-05 |
阿斯利康(瑞典)有限公司 |
抑制磷酸肌醇3-激酶β
|
US20040048853A1
(en)
|
2002-08-21 |
2004-03-11 |
Gustave Bergnes |
Compounds, compositions, and methods
|
US20030139427A1
(en)
|
2002-08-23 |
2003-07-24 |
Osi Pharmaceuticals Inc. |
Bicyclic pyrimidinyl derivatives and methods of use thereof
|
WO2004020599A2
(en)
|
2002-08-29 |
2004-03-11 |
Curis, Inc. |
Hedgehog antagonists, methods and uses related thereto
|
GB0220319D0
(en)
|
2002-09-02 |
2002-10-09 |
Cancer Res Campaign Tech |
Enzyme activated self-immolative nitrogen mustard drugs
|
AU2003266668A1
(en)
|
2002-09-30 |
2004-04-23 |
Banyu Pharmaceutical Co., Ltd. |
2-aminobenzimidazole derivative
|
CA2500727A1
(en)
|
2002-10-03 |
2004-04-15 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
US20050282814A1
(en)
|
2002-10-03 |
2005-12-22 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
US20040146941A1
(en)
|
2002-11-04 |
2004-07-29 |
Biliang Zhang |
Chemical encoding technology for combinatorial synthesis
|
JP2004161716A
(ja)
|
2002-11-15 |
2004-06-10 |
Takeda Chem Ind Ltd |
Jnk阻害剤
|
WO2004046128A1
(en)
|
2002-11-21 |
2004-06-03 |
Vicore Pharma Ab |
New bicyclic angiotensin ii agonists
|
ATE496893T1
(de)
|
2002-12-20 |
2011-02-15 |
X Ceptor Therapeutics Inc |
Isochinolinonderivate und deren verwendung als medikamente
|
WO2004056746A1
(en)
|
2002-12-23 |
2004-07-08 |
4Sc Ag |
Cycloalkene dicarboxylic acid compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
|
US7247736B2
(en)
|
2002-12-23 |
2007-07-24 |
4Sc Ag |
Method of identifying inhibitors of DHODH
|
US7365094B2
(en)
|
2002-12-23 |
2008-04-29 |
4Sc Ag |
Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
|
FR2850022B1
(fr)
|
2003-01-22 |
2006-09-08 |
Centre Nat Rech Scient |
Nouvelle utilisation de la mifepristone et de ses derives comme modulateurs de la voie de signalisation des proteines hedgehog et ses applications
|
WO2004075917A1
(ja)
|
2003-02-28 |
2004-09-10 |
Toudai Tlo, Ltd. |
器官または組織の線維化抑制剤
|
WO2004078702A1
(en)
|
2003-03-06 |
2004-09-16 |
Dsm Ip Assets B.V. |
PROCESS FOR THE PREPARATION OF AN α-AMINO CARBONYL COMPOUND
|
TW200505902A
(en)
|
2003-03-20 |
2005-02-16 |
Schering Corp |
Cannabinoid receptor ligands
|
US7687625B2
(en)
|
2003-03-25 |
2010-03-30 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
GB0306907D0
(en)
|
2003-03-26 |
2003-04-30 |
Angiogene Pharm Ltd |
Boireductively-activated prodrugs
|
WO2004087679A1
(en)
|
2003-04-01 |
2004-10-14 |
Aponetics Ag |
2, 4, 6-trisubstituted pyrimidine derivatives useful for the treatment of neoplastic and autoimmune diseases
|
US7217794B2
(en)
|
2003-04-02 |
2007-05-15 |
Daiamed, Inc. |
Compounds and methods for treatment of thrombosis
|
WO2004089877A1
(en)
|
2003-04-14 |
2004-10-21 |
Astrazeneca Ab |
New hydroxynaphthyl amides
|
US7317027B2
(en)
|
2003-05-19 |
2008-01-08 |
Sanofi-Aventis Deutschland Gmbh |
Azaindole-derivatives as factor Xa inhibitors
|
US7223780B2
(en)
|
2003-05-19 |
2007-05-29 |
Sanofi-Aventis Deutschland Gmbh |
Triazole-derivatives as blood clotting enzyme factor Xa inhibitors
|
EP1479675A1
(en)
|
2003-05-19 |
2004-11-24 |
Aventis Pharma Deutschland GmbH |
Indazole-derivatives as factor Xa inhibitors
|
WO2004111014A1
(en)
|
2003-06-06 |
2004-12-23 |
Vertex Pharmaceuticals Incorporated |
Pyrimidine derivatives as modulators of atp-binding cassette transporters
|
US7429596B2
(en)
|
2003-06-20 |
2008-09-30 |
The Regents Of The University Of California |
1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof
|
WO2005002585A1
(en)
|
2003-07-02 |
2005-01-13 |
Warner-Lambert Company Llc |
Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
|
WO2005013800A2
(en)
|
2003-07-15 |
2005-02-17 |
The Johns Hopkins University |
Elevated hedgehog pathway activity in digestive system tumors, and methods of treating digestive system tumors having elevated hedgehog pathway activity
|
GB0317951D0
(en)
|
2003-07-31 |
2003-09-03 |
Trigen Ltd |
Compounds
|
US7459472B2
(en)
|
2003-08-08 |
2008-12-02 |
Transtech Pharma, Inc. |
Aryl and heteroaryl compounds, compositions, and methods of use
|
US7208601B2
(en)
|
2003-08-08 |
2007-04-24 |
Mjalli Adnan M M |
Aryl and heteroaryl compounds, compositions, and methods of use
|
US20050054614A1
(en)
|
2003-08-14 |
2005-03-10 |
Diacovo Thomas G. |
Methods of inhibiting leukocyte accumulation
|
WO2005016348A1
(en)
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
MXPA06001758A
(es)
|
2003-08-15 |
2006-08-11 |
Irm Llc |
Anilino purinas sustituidas en la posicion 6 utiles como inhibidores de rtk.
|
US7390820B2
(en)
|
2003-08-25 |
2008-06-24 |
Amgen Inc. |
Substituted quinolinone derivatives and methods of use
|
WO2005044181A2
(en)
|
2003-09-09 |
2005-05-19 |
Temple University-Of The Commonwealth System Of Higher Education |
Protection of tissues and cells from cytotoxic effects of ionizing radiation by abl inhibitors
|
GB0322409D0
(en)
|
2003-09-25 |
2003-10-29 |
Astrazeneca Ab |
Quinazoline derivatives
|
US8067608B2
(en)
|
2003-09-29 |
2011-11-29 |
The Johns Hopkins University |
Hedgehog pathway antagonists
|
WO2005032343A2
(en)
|
2003-10-01 |
2005-04-14 |
The Johns Hopkins University |
Hedgehog signaling in prostate regeneration neoplasia and metastasis
|
WO2005042700A2
(en)
|
2003-10-20 |
2005-05-12 |
The Johns Hopkins University |
Use of hedgehog pathway inhibitors in small-cell lung cancer
|
AU2004289303A1
(en)
|
2003-11-10 |
2005-05-26 |
Synta Pharmaceuticals, Corp. |
Fused heterocyclic compounds
|
JP2007511596A
(ja)
|
2003-11-17 |
2007-05-10 |
ファイザー・プロダクツ・インク |
癌の治療において有用なピロロピリミジン化合物
|
US7449477B2
(en)
|
2003-11-25 |
2008-11-11 |
Eli Lilly And Company |
7-phenyl-isoquinoline-5-sulfonylamino derivatives as inhibitors of akt (protein kinase B)
|
EP1692112A4
(en)
|
2003-12-08 |
2008-09-24 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS, AND METHODS
|
AU2004308974A1
(en)
|
2003-12-22 |
2005-07-14 |
Gilead Sciences, Inc. |
Kinase inhibitor phosphonate conjugates
|
AU2004309420B2
(en)
|
2003-12-23 |
2008-10-30 |
Novartis Ag |
Bicyclic heterocyclic p-38 kinase inhibitors
|
CA2552664A1
(en)
|
2004-01-08 |
2005-07-28 |
Michigan State University |
Methods for treating and preventing hypertension and hypertension-related disorders
|
US20050214310A1
(en)
|
2004-01-23 |
2005-09-29 |
Seattle Genetics, Inc. |
Melphalan prodrugs
|
CA2553724A1
(en)
|
2004-02-03 |
2005-08-18 |
Abbott Laboratories |
Aminobenzoxazoles as therapeutic agents
|
WO2005074606A2
(en)
|
2004-02-03 |
2005-08-18 |
Rochester Institute Of Technology |
Method of photolithography using a fluid and a system thereof
|
UA83416C2
(en)
*
|
2004-02-13 |
2008-07-10 |
Баниу Фармасьютикал Ко., Лтд. |
Fused ring 4-oxopyrimidine derivative
|
US20050187418A1
(en)
|
2004-02-19 |
2005-08-25 |
Small Brooke L. |
Olefin oligomerization
|
CA2556589A1
(en)
|
2004-02-24 |
2005-09-01 |
Bioaxone Therapeutique Inc. |
4-substituted piperidine derivatives
|
EP1568698A1
(en)
|
2004-02-27 |
2005-08-31 |
Aventis Pharma Deutschland GmbH |
Pyrrole-derivatives as factor Xa inhibitors
|
BRPI0508036A
(pt)
|
2004-02-27 |
2007-07-17 |
Hoffmann La Roche |
derivados fundidos de pirazola
|
EP1571154A1
(en)
|
2004-03-03 |
2005-09-07 |
Aventis Pharma Deutschland GmbH |
Beta-aminoacid-derivatives as factor Xa inhibitors
|
JP4832426B2
(ja)
|
2004-04-02 |
2011-12-07 |
オーエスアイ・ファーマスーティカルズ・インコーポレーテッド |
6,6−二環置換されたヘテロ二環式タンパク質キナーゼ阻害剤
|
MXPA06012333A
(es)
|
2004-04-30 |
2007-01-17 |
Takeda Pharmaceutical |
Compuesto de amida heterociclico y uso del mismo como un inhibidor mmp-13.
|
CN101018783B
(zh)
|
2004-04-30 |
2012-11-21 |
遗传技术研究公司 |
Hedgehog信号传导途径的喹喔啉抑制剂
|
DE102004022897A1
(de)
|
2004-05-10 |
2005-12-08 |
Bayer Cropscience Ag |
Azinyl-imidazoazine
|
CA2730540A1
(en)
|
2004-05-13 |
2005-12-01 |
Vanderbilt University |
Phosphoinositide 3-kinase delta selective inhibitors for inhibiting angiogenesis
|
CA2566609C
(en)
|
2004-05-13 |
2012-06-26 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
CA2567883A1
(en)
|
2004-05-25 |
2005-12-15 |
Icos Corporation |
Methods for treating and/or preventing aberrant proliferation of hematopoietic cells
|
EP1750715A1
(en)
*
|
2004-06-04 |
2007-02-14 |
Icos Corporation |
Methods for treating mast cell disorders
|
GB0413605D0
(en)
|
2004-06-17 |
2004-07-21 |
Addex Pharmaceuticals Sa |
Novel compounds
|
WO2006007501A2
(en)
|
2004-07-01 |
2006-01-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
US20060019967A1
(en)
|
2004-07-21 |
2006-01-26 |
Su-Ying Wu |
SARS CoV main protease inhibitors
|
WO2006015279A1
(en)
|
2004-07-28 |
2006-02-09 |
Neurogen Corporation |
Heterocyclic diamine compounds as ligands of the melanin concentrating hormone receptor useful for the treatment of obesity, diabetes, eating and sexual disorders
|
BRPI0514444A
(pt)
|
2004-08-27 |
2008-06-10 |
Infinity Pharmaceuticals Inc |
análogos de ciclopamina e métodos de uso destes
|
CN102964294A
(zh)
|
2004-09-02 |
2013-03-13 |
遗传技术研究公司 |
Hedgehog信号转导的吡啶基抑制剂
|
GB0420722D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
WO2006038865A1
(en)
|
2004-10-01 |
2006-04-13 |
Betagenon Ab |
Nucleotide derivatives for the treatment of type 2 diabetes and other disorders
|
KR20070083836A
(ko)
|
2004-10-28 |
2007-08-24 |
아이알엠 엘엘씨 |
헷지혹 경로 조절제로서의 화합물 및 조성물
|
US8212012B2
(en)
|
2004-11-03 |
2012-07-03 |
University Of Kansas |
Novobiocin analogues having modified sugar moieties
|
CA2585091C
(en)
|
2004-11-03 |
2016-07-19 |
University Of Kansas |
Novobiocin analogues as anticancer agents
|
US7622451B2
(en)
|
2004-11-03 |
2009-11-24 |
University Of Kansas |
Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
|
US8212011B2
(en)
|
2004-11-03 |
2012-07-03 |
University Of Kansas |
Novobiocin analogues
|
GB0425035D0
(en)
|
2004-11-12 |
2004-12-15 |
Novartis Ag |
Organic compounds
|
US9512125B2
(en)
|
2004-11-19 |
2016-12-06 |
The Regents Of The University Of California |
Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
|
MX2007006178A
(es)
|
2004-11-23 |
2007-06-20 |
Ptc Therapeutics Inc |
Fenoles substituidos como agentes activos que inhiben la produccion del factor de crecimiento endotelial vascular.
|
JP2008521862A
(ja)
|
2004-12-01 |
2008-06-26 |
デブジェン エヌブイ |
イオンチャンネル、特にkvファミリーのイオンチャンネルと相互作用する5−カルボキサミド置換チアゾール誘導体
|
US20060156485A1
(en)
|
2005-01-14 |
2006-07-20 |
The Procter & Gamble Company |
Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
|
GB0501999D0
(en)
|
2005-02-01 |
2005-03-09 |
Sentinel Oncology Ltd |
Pharmaceutical compounds
|
EP1885356A2
(en)
|
2005-02-17 |
2008-02-13 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
US7579348B2
(en)
|
2005-02-25 |
2009-08-25 |
Pgxhealth, Llc |
Derivatives of 8-substituted xanthines
|
US20090124654A1
(en)
|
2005-03-01 |
2009-05-14 |
Mjalli Adnan M M |
Aryl and Heteroaryl Compounds, Compositions, Methods of Use
|
US7872050B2
(en)
|
2005-03-14 |
2011-01-18 |
Yaupon Therapeutics Inc. |
Stabilized compositions of volatile alkylating agents and methods of using thereof
|
MX2007012449A
(es)
|
2005-04-06 |
2007-12-05 |
Irm Llc |
Compuestos y composiciones que contienen diaril-amina, y su uso como moduladores de los receptores nucleares de hormonas esteroideas.
|
KR100781704B1
(ko)
|
2005-04-20 |
2007-12-03 |
에스케이케미칼주식회사 |
피리딘 유도체와 이의 제조방법, 및 이를 포함하는약제조성물
|
WO2006114065A2
(en)
|
2005-04-25 |
2006-11-02 |
Institute Of Organic Chemistry And Biochemistry A Cademy Of Sciences Of The Czech Republic |
Use of compounds to inhibit neoplasia
|
CN100526315C
(zh)
|
2005-06-16 |
2009-08-12 |
浙江医药股份有限公司新昌制药厂 |
N2-喹啉或异喹啉取代的嘌呤衍生物及其制备方法和其用途
|
SI1906965T1
(sl)
|
2005-06-22 |
2015-09-30 |
Chemocentryx, Inc. |
Azaindolne spojine in postopki uporabe
|
ATE474829T1
(de)
|
2005-06-27 |
2010-08-15 |
Amgen Inc |
Entzündungshemmende arylnitrilverbindungen
|
JP2009505948A
(ja)
|
2005-07-11 |
2009-02-12 |
デブジェン エヌブイ |
キナーゼ阻害剤としてのアミド誘導体
|
WO2007006547A1
(en)
|
2005-07-11 |
2007-01-18 |
Devgen N.V. |
Amide derivatives as kinase inhibitors
|
WO2007029121A2
(en)
|
2005-07-21 |
2007-03-15 |
Galderma Research & Development |
Novel cyclopent-2-en-1-one derivatives which are ppar receptor modulators, and use thereof in pharmaceutical or cosmetic compositions
|
US20070017915A1
(en)
|
2005-07-22 |
2007-01-25 |
Weder Donald E |
Collapsible and/or erectable substantially egg-shaped container
|
US7700552B2
(en)
|
2005-07-29 |
2010-04-20 |
Medivir Ab |
Macrocyclic inhibitors of hepatitis C virus
|
GB0516723D0
(en)
|
2005-08-15 |
2005-09-21 |
Novartis Ag |
Organic compounds
|
MX2008002385A
(es)
|
2005-08-25 |
2008-03-18 |
Hoffmann La Roche |
Inhibidores de proteinas cinasas activads por mitogenos p38 y metodos para utilizarlos.
|
US20070049591A1
(en)
|
2005-08-25 |
2007-03-01 |
Kalypsys, Inc. |
Inhibitors of MAPK/Erk Kinase
|
EP1919873A1
(de)
|
2005-09-01 |
2008-05-14 |
BioAgency AG |
Fredericamycin-derivate
|
US20100022531A1
(en)
|
2005-09-01 |
2010-01-28 |
Renovis, Inc. |
Novel compounds as p2x7 modulators and uses thereof
|
US20070072897A1
(en)
|
2005-09-29 |
2007-03-29 |
Wyeth |
Phenylaminopropanol derivatives and methods of their use
|
FR2892859B1
(fr)
|
2005-10-27 |
2008-06-06 |
Commissariat Energie Atomique |
Procede de greffage de molecules d'interet sur des surfaces inorganiques, surfaces obtenues et applications
|
WO2007054623A2
(en)
|
2005-11-11 |
2007-05-18 |
Licentia Oy |
Mammalian hedgehog signaling inhiabitors
|
EP1957461B1
(en)
|
2005-11-14 |
2016-11-02 |
Genentech, Inc. |
Bisamide inhibitors of hedgehog signaling
|
BRPI0618622A2
(pt)
|
2005-11-17 |
2011-09-06 |
Osi Pharm Inc |
composto, composição, e, uso de um composto
|
US8642278B2
(en)
|
2005-11-22 |
2014-02-04 |
University Of South Florida |
Inhibition of cell proliferation
|
CA2629192A1
(en)
|
2005-11-22 |
2007-05-31 |
Merck & Co., Inc. |
Indole orexin receptor antagonists
|
WO2007075554A2
(en)
|
2005-12-19 |
2007-07-05 |
Osi Pharmaceuticals, Inc. |
Combination of igfr inhibitor and anti-cancer agent
|
US7572809B2
(en)
|
2005-12-19 |
2009-08-11 |
Hoffmann-La Roche Inc. |
Isoquinoline aminopyrazole derivatives
|
CN101389630A
(zh)
|
2005-12-29 |
2009-03-18 |
艾博特公司 |
蛋白激酶抑制剂
|
ES2566479T3
(es)
|
2006-01-06 |
2016-04-13 |
Sunovion Pharmaceuticals Inc. |
Inhibidores de reabsorción de monoamina con base en tetralona
|
WO2007094912A2
(en)
|
2006-01-13 |
2007-08-23 |
University Of Kentucky |
Bis-quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors
|
WO2007089669A2
(en)
|
2006-01-26 |
2007-08-09 |
Wyeth |
Processes for the preparation of compounds which modulate cell proliferation
|
PE20071025A1
(es)
|
2006-01-31 |
2007-10-17 |
Mitsubishi Tanabe Pharma Corp |
Compuesto amina trisustituido
|
US7723330B2
(en)
|
2006-03-07 |
2010-05-25 |
Array Biopharma Inc. |
Heterobicyclic pyrazole compounds and methods of use
|
DK2004683T3
(en)
|
2006-03-24 |
2016-08-22 |
Biogen Hemophilia Inc |
PC5 AS A FACTOR IX PROPEPTID PROCESSING ENZYM
|
EP2007373A4
(en)
|
2006-03-29 |
2012-12-19 |
Foldrx Pharmaceuticals Inc |
INHIBITION OF ALPHA SYNUCLEINE TOXICITY
|
US20080032960A1
(en)
|
2006-04-04 |
2008-02-07 |
Regents Of The University Of California |
PI3 kinase antagonists
|
CA2648207A1
(en)
|
2006-04-13 |
2007-10-25 |
Vertex Pharmaceuticals Incorporated |
Thiophene-carboxamides useful as inhibitors of protein kinases
|
MX2008013204A
(es)
|
2006-04-14 |
2008-10-22 |
Novartis Ag |
Uso de biarilcarboxamidas en el tratamiento de trastornos relacionados con la ruta hedgehog.
|
WO2007121453A2
(en)
|
2006-04-17 |
2007-10-25 |
The Regents Of The University Of California |
2-hydroxy-1-oxo 1,2 dihydro isoquinoline chelating agents
|
GB0607950D0
(en)
|
2006-04-21 |
2006-05-31 |
Novartis Ag |
Organic compounds
|
GB0607948D0
(en)
|
2006-04-21 |
2006-05-31 |
Novartis Ag |
Organic compounds
|
ATE549337T1
(de)
|
2006-04-21 |
2012-03-15 |
Novartis Ag |
Purinderivate zur verwendung als adenosin-a2a- rezeptoragonisten
|
WO2007125315A2
(en)
|
2006-04-25 |
2007-11-08 |
Astex Therapeutics Limited |
Pharmaceutical compounds
|
WO2007125310A2
(en)
|
2006-04-25 |
2007-11-08 |
Astex Therapeutics Limited |
Pharmaceutical combinations of pk inhibitors and other active agents
|
DE102006020327A1
(de)
|
2006-04-27 |
2007-12-27 |
Bayer Healthcare Ag |
Heterocyclisch substituierte, anellierte Pyrazol-Derivate und ihre Verwendung
|
UA93548C2
(uk)
|
2006-05-05 |
2011-02-25 |
Айерем Елелсі |
Сполуки та композиції як модулятори хеджхогівського сигнального шляху
|
EP2029593A1
(en)
|
2006-05-22 |
2009-03-04 |
AstraZeneca AB |
Indole derivatives
|
GB0610242D0
(en)
|
2006-05-23 |
2006-07-05 |
Novartis Ag |
Organic compounds
|
GB0610317D0
(en)
|
2006-05-24 |
2006-07-05 |
Medical Res Council |
Antiparasitic compounds and compositions
|
EP1859772B1
(en)
|
2006-05-24 |
2010-12-15 |
Guardant S.r.l. |
Alkalized local anesthetic in bag
|
DE602007006835D1
(de)
|
2006-07-20 |
2010-07-08 |
Amgen Inc |
Substituierte pyridonverbindungen und anwendungsverfahren
|
MX2009000864A
(es)
|
2006-07-28 |
2009-02-03 |
Novartis Ag |
Quinazolinas 2,4-sustituidas como inhibidores de cinasa de lipido.
|
WO2008020203A1
(en)
|
2006-08-17 |
2008-02-21 |
Astrazeneca Ab |
Pyridinylquinaz0linamine derivatives and their use as b-raf inhibitors
|
US8541428B2
(en)
|
2006-08-22 |
2013-09-24 |
Technion Research And Development Foundation Ltd. |
Heterocyclic derivatives, pharmaceutical compositions and methods of use thereof
|
CA2661436A1
(en)
|
2006-08-24 |
2008-02-28 |
Serenex, Inc. |
Isoquinoline, quinazoline and phthalazine derivatives
|
WO2008025755A1
(de)
|
2006-09-01 |
2008-03-06 |
Basf Se |
Verwendung von n-haltigen heterozyklen in dermokosmetika
|
MX2009002298A
(es)
|
2006-09-01 |
2009-06-04 |
Cylene Pharmaceuticals Inc |
Moduladores de serina-treonina proteina quinasa y de parp.
|
EP1903044A1
(en)
|
2006-09-14 |
2008-03-26 |
Novartis AG |
Adenosine Derivatives as A2A Receptor Agonists
|
EP2064234B1
(en)
|
2006-09-18 |
2011-11-02 |
Compugen Ltd. |
Bioactive peptides and method of using same
|
US8492405B2
(en)
|
2006-10-18 |
2013-07-23 |
Takeda Pharmaceutical Company Limited |
Glucokinase-activating fused heterocyclic compounds and methods of treating diabetes and obesity
|
SG178743A1
(en)
|
2006-10-31 |
2012-03-29 |
Us Gov Health & Human Serv |
Smoothened polypeptides and methods of use
|
US7772180B2
(en)
|
2006-11-09 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
CN101605797A
(zh)
|
2006-11-13 |
2009-12-16 |
伊莱利利公司 |
治疗炎症疾病和癌症的噻吩并嘧啶酮
|
WO2008063625A2
(en)
|
2006-11-20 |
2008-05-29 |
Adolor Corporation |
Pyridine compounds and methods of their use
|
US8436177B2
(en)
|
2006-11-20 |
2013-05-07 |
Novartis Ag |
Salts and crystall forms of 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile
|
JP2010512331A
(ja)
|
2006-12-06 |
2010-04-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グルココルチコイド模倣薬、それらの製造方法、医薬組成物、及びこれらの使用
|
BRPI0720546A2
(pt)
|
2006-12-14 |
2015-06-23 |
Daiichi Sankyo Co Ltd |
Composto, inibidor, medicamento, agente antitumor, composição farmacêutica, método para tratar câncer, e, uso do composto
|
EP2132178B1
(en)
|
2006-12-20 |
2015-08-19 |
Merck Sharp & Dohme Corp. |
Jnk inhibitors
|
DK2114925T3
(da)
|
2006-12-22 |
2012-05-29 |
Ind Res Ltd |
Azetidin-analoger af nucleosidase- og phosphorylase-inhibitorer
|
TWI433674B
(zh)
|
2006-12-28 |
2014-04-11 |
Infinity Discovery Inc |
環杷明(cyclopamine)類似物類
|
BRPI0807182A2
(pt)
|
2007-01-26 |
2014-05-27 |
Irm Llc |
Compostos e composições como inibidores de cinase
|
WO2008103354A2
(en)
|
2007-02-20 |
2008-08-28 |
Cropsolution, Inc. |
Modulators of acetyl-coenzyme a carboxylase and methods of use thereof
|
EP2129677B1
(en)
|
2007-03-07 |
2014-12-17 |
Infinity Discovery, Inc. |
Heterocyclic cyclopamine analogs and methods of use thereof
|
WO2008109829A1
(en)
|
2007-03-07 |
2008-09-12 |
Infinity Pharmaceuticals, Inc. |
Cyclopamine lactam analogs and methods of use thereof
|
WO2008112715A2
(en)
|
2007-03-12 |
2008-09-18 |
Vm Discovery Inc. |
Novel agents of calcium ion channel modulators
|
EP2527330A1
(en)
|
2007-03-14 |
2012-11-28 |
Exelixis, Inc. |
Inhibitors of the hedgehog pathway
|
PE20090188A1
(es)
|
2007-03-15 |
2009-03-20 |
Novartis Ag |
Compuestos heterociclicos como moduladores de la senda de hedgehog
|
WO2008118454A2
(en)
|
2007-03-23 |
2008-10-02 |
Amgen Inc. |
Derivatives of quinoline or benzopyrazine and their uses for the treatment of (inter alia) inflammatory diseases, autoimmune diseases or various kinds of cancer
|
ES2563458T3
(es)
|
2007-03-23 |
2016-03-15 |
Amgen Inc. |
Compuestos heterocíclicos y sus usos
|
PT2139882E
(pt)
|
2007-03-23 |
2014-01-30 |
Amgen Inc |
Derivados de quinolina ou quinoxalina 3-substituídos e sua utilização como inibidores de fosfatidilinositol 3-cinase (pi3k)
|
WO2008117050A1
(en)
|
2007-03-27 |
2008-10-02 |
Astrazeneca Ab |
Pyrazolyl-amino-substituted pyrazines and their use for the treatment of cancer
|
US7867983B2
(en)
|
2007-03-29 |
2011-01-11 |
The University Of Connecticut |
Methods to protect skeletal muscle against injury
|
CN101636397B
(zh)
|
2007-04-13 |
2012-06-13 |
中国人民解放军军事医学科学院毒物药物研究所 |
脲类化合物、其制备方法及其医药用途
|
EP2134682B1
(en)
|
2007-04-13 |
2011-12-14 |
Sanofi |
A transition metal catalyzed synthesis of n-aminoindoles
|
US20090054517A1
(en)
|
2007-04-20 |
2009-02-26 |
Lubahn Dennis B |
Phytoestrogens As Regulators Of Hedgehog Signaling And Methods Of Their Use In Cancer Treatment
|
JP2010163361A
(ja)
|
2007-04-27 |
2010-07-29 |
Dainippon Sumitomo Pharma Co Ltd |
キノリン誘導体
|
US7960353B2
(en)
|
2007-05-10 |
2011-06-14 |
University Of Kansas |
Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
|
US20090214529A9
(en)
|
2007-05-22 |
2009-08-27 |
Taigen Biotechnology Co., Ltd. |
Kinesin inhibitors
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
US9603848B2
(en)
|
2007-06-08 |
2017-03-28 |
Senomyx, Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
EP2167058B1
(en)
|
2007-06-18 |
2015-08-12 |
University Of Louisville Research Foundation, Inc. |
Family of pfkfb3 inhibitors with anti-neoplastic activities
|
US8557823B2
(en)
|
2007-06-18 |
2013-10-15 |
Advanced Cancer Therapeutics, Llc |
Family of PFKFB3 inhibitors with anti-neoplastic activities
|
US8541593B2
(en)
|
2007-06-21 |
2013-09-24 |
Amgen Inc. |
Process for making substituted 2-amino-thiazolones
|
EP2511253A3
(en)
|
2007-06-22 |
2012-12-19 |
North Carolina State University |
Methods of inhibiting ethylene responses in plants using dicyclopropene compounds
|
EP2173747B1
(en)
|
2007-06-26 |
2011-12-21 |
Sanofi |
A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
|
EP2170274A1
(en)
|
2007-07-02 |
2010-04-07 |
Technion Research and Development Foundation, Ltd. |
Compositions, articles and methods comprising tspo ligands for preventing or reducing tobacco-associated damage
|
RU2345996C1
(ru)
|
2007-07-17 |
2009-02-10 |
Андрей Александрович Иващенко |
Аннелированные азагетероциклические амиды, включающие пиримидиновый фрагмент, способ их получения и применения
|
JP4834699B2
(ja)
|
2007-07-30 |
2011-12-14 |
田辺三菱製薬株式会社 |
医薬組成物
|
JP4846769B2
(ja)
|
2007-07-30 |
2011-12-28 |
田辺三菱製薬株式会社 |
医薬組成物
|
CA2696113A1
(en)
|
2007-08-10 |
2009-04-02 |
Burnham Institute For Medical Research |
Tissue-nonspecific alkaline phosphatase (tnap) activators and uses thereof
|
CN106279283A
(zh)
|
2007-08-13 |
2017-01-04 |
症变治疗公司 |
新颖的葡糖激酶活化剂
|
WO2009029617A1
(en)
|
2007-08-27 |
2009-03-05 |
Kalypsys, Inc. |
Diarylamine-substituted quinolones useful as inducible nitric oxide synthase inhibitors
|
JP5227965B2
(ja)
|
2007-10-03 |
2013-07-03 |
独立行政法人理化学研究所 |
ニトロトリアゾール誘導体、およびそれを用いる化合物の製造方法
|
KR20100089082A
(ko)
|
2007-10-15 |
2010-08-11 |
아스트라제네카 아베 |
조합 059
|
AU2008321099A1
(en)
|
2007-11-13 |
2009-05-22 |
Icos Corporation |
Inhibitors of human phosphatidyl-inositol 3-kinase delta
|
CA2709203A1
(en)
|
2007-12-13 |
2009-06-18 |
Siena Biotech S.P.A. |
Hedgehog pathway antagonists and therapeutic applications thereof
|
US20090163481A1
(en)
|
2007-12-13 |
2009-06-25 |
Murphy Brian J |
Ppar-delta ligands and methods of their use
|
US8399483B2
(en)
|
2007-12-21 |
2013-03-19 |
Ucb Pharma S.A. |
Quinoxaline and quinoline derivatives as kinase inhibitors
|
US7960397B2
(en)
|
2007-12-28 |
2011-06-14 |
Institute Of Experimental Botany, Academy Of Sciences Of The Czech Republic |
6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
NZ613219A
(en)
*
|
2008-01-04 |
2014-11-28 |
Intellikine Llc |
Heterocyclic containing entities, compositions and methods
|
EA201001135A1
(ru)
|
2008-01-09 |
2011-02-28 |
ПиДжиИксХЭЛС ЭлЭлСи |
Интратекальное лечение невропатической боли агонистами ar
|
WO2009100406A2
(en)
|
2008-02-07 |
2009-08-13 |
Synta Pharmaceuticals Corp. |
Topical formulations for the treatment of psoriasis
|
JP2011511802A
(ja)
|
2008-02-07 |
2011-04-14 |
ギリアード・パロ・アルト・インコーポレイテッド |
Abca−1を上昇させる化合物およびかかる化合物の使用方法
|
WO2009103022A1
(en)
|
2008-02-13 |
2009-08-20 |
Itherx Pharmaceuticals, Inc. |
Derivatives of substituted fused ring cycloindoles and methods of their use
|
TWI444384B
(zh)
|
2008-02-20 |
2014-07-11 |
Gilead Sciences Inc |
核苷酸類似物及其在治療惡性腫瘤上的用途
|
WO2009105782A1
(en)
|
2008-02-21 |
2009-08-27 |
Sequoia Pharmaceuticals, Inc. |
Hiv protease inhibitor and cytochrome p450 inhibitor combinations
|
WO2009114874A2
(en)
|
2008-03-14 |
2009-09-17 |
Intellikine, Inc. |
Benzothiazole kinase inhibitors and methods of use
|
JP5547099B2
(ja)
|
2008-03-14 |
2014-07-09 |
インテリカイン, エルエルシー |
キナーゼ阻害剤および使用方法
|
MX2010010151A
(es)
|
2008-03-20 |
2010-10-25 |
Amgen Inc |
Moduladores de cinasa aurora y metodo de uso.
|
WO2009118765A2
(en)
|
2008-03-28 |
2009-10-01 |
Panacea Biotec Limited |
Novel monoamine re-uptake inhibitor
|
EP2279188B1
(en)
|
2008-05-30 |
2015-01-28 |
Genentech, Inc. |
Purine pi3k inhibitor compounds and methods of use
|
US20090312406A1
(en)
|
2008-06-12 |
2009-12-17 |
Hsing-Pang Hsieh |
Coumarin compounds and their use for treating viral infection
|
JP2011524914A
(ja)
|
2008-06-20 |
2011-09-08 |
アムジエン・インコーポレーテツド |
置換2−アミノ−チアゾロンを作製するための方法
|
CN102124009B
(zh)
|
2008-07-08 |
2014-07-23 |
因特利凯公司 |
激酶抑制剂及其使用方法
|
US20110224223A1
(en)
|
2008-07-08 |
2011-09-15 |
The Regents Of The University Of California, A California Corporation |
MTOR Modulators and Uses Thereof
|
CA2730610A1
(en)
|
2008-07-16 |
2010-01-21 |
Schering Corporation |
Bicyclic heterocycle derivatives and their use as gpcr modulators
|
US8450344B2
(en)
|
2008-07-25 |
2013-05-28 |
Aerie Pharmaceuticals, Inc. |
Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
|
CN102177152A
(zh)
|
2008-08-11 |
2011-09-07 |
哈佛大学校长及研究员协会 |
用于抑制tRNA合成酶的卤夫酮(halofuginone)类似物和其用途
|
WO2010019921A2
(en)
|
2008-08-15 |
2010-02-18 |
The Regents Of The University Of California |
Biomarkers for diagnosis and treatment of chronic lymphocytic leukemia
|
US20100063047A1
(en)
|
2008-09-10 |
2010-03-11 |
Kalypsys, Inc. |
Aminopyrimidine inhibitors of histamine receptors for the treatment of disease
|
EP2344481B9
(en)
|
2008-09-23 |
2014-12-31 |
Georgetown University |
Viral and fungal inhibitors
|
WO2010036380A1
(en)
|
2008-09-26 |
2010-04-01 |
Intellikine, Inc. |
Heterocyclic kinase inhibitors
|
EP2177510A1
(en)
|
2008-10-17 |
2010-04-21 |
Universität des Saarlandes |
Allosteric protein kinase modulators
|
US8476431B2
(en)
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
WO2010053998A1
(en)
|
2008-11-05 |
2010-05-14 |
Xenon Pharmaceuticals, Inc. |
Spiro-condensed indole derivatives as sodium channel inhibitors
|
NZ611764A
(en)
|
2008-11-13 |
2015-01-30 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
US20110269779A1
(en)
|
2008-11-18 |
2011-11-03 |
Intellikine, Inc. |
Methods and compositions for treatment of ophthalmic conditions
|
CA2745280A1
(en)
|
2008-12-04 |
2010-06-10 |
The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services |
Phosphatidylinositol-3-kinase p110 delta-targeted drugs in the treatment of cns disorders
|
EA020548B1
(ru)
|
2008-12-19 |
2014-12-30 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Циклические пиримидин-4-карбоксамиды в качестве антагонистов рецептора ccr2, предназначенные для лечения воспаления, астмы и хозл
|
US20110135655A1
(en)
|
2009-01-13 |
2011-06-09 |
PHILADELPHIA HEALTH AND EDUCATION CORPORATION d/b/a Drexel University College of Medicine; |
Role of PI3K p110 delta Signaling in Retroviral Infection and Replication
|
CA2749585A1
(en)
|
2009-01-13 |
2010-07-22 |
Van Andel Research Institute |
Methods of using substituted isoxazolo pyridinones as dissociated glucocorticoids
|
WO2010092340A1
(en)
|
2009-02-13 |
2010-08-19 |
Ucb Pharma S.A. |
Fused pyridine and pyrazine derivatives as kinase inhibitors
|
TW201038569A
(en)
|
2009-02-16 |
2010-11-01 |
Abbott Gmbh & Co Kg |
Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
|
US20100280067A1
(en)
|
2009-04-30 |
2010-11-04 |
Pakala Kumara Savithru Sarma |
Inhibitors of acetyl-coa carboxylase
|
EP2427195B1
(en)
|
2009-05-07 |
2019-05-01 |
Intellikine, LLC |
Heterocyclic compounds and uses thereof
|
AU2010249790A1
(en)
|
2009-05-22 |
2011-12-08 |
Exelixis, Inc. |
Benzoxazepines based P13K/mT0R inhibitors against proliferative diseases
|
GB0908957D0
(en)
|
2009-05-22 |
2009-07-01 |
Ucb Pharma Sa |
Therapeutic agents
|
WO2010138487A1
(en)
|
2009-05-26 |
2010-12-02 |
Exelixis, Inc. |
BENZOXAZEPINES AS INHIBITORS OF PI3K/m TOR AND METHODS OF THEIR USE AND MANUFACTURE
|
WO2010136491A1
(en)
|
2009-05-27 |
2010-12-02 |
F. Hoffmann-La Roche Ag |
Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
JP5781066B2
(ja)
|
2009-05-27 |
2015-09-16 |
ジェネンテック, インコーポレイテッド |
p110δに対して選択的な二環式ピリミジンPI3K阻害剤化合物及び使用方法
|
CN101602768B
(zh)
|
2009-07-17 |
2012-05-30 |
河南省农科院农副产品加工研究所 |
一种芝麻素和芝麻林素的提纯方法
|
US8969636B2
(en)
|
2009-07-29 |
2015-03-03 |
The United States Of America As Represented By The Secretary Of The Navy |
Homogeneous metallocene ziegler-natta catalysts for the oligomerization of olefins in aliphatic-hydrocarbon solvents
|
US9212177B2
(en)
|
2009-08-05 |
2015-12-15 |
Versitech Limited |
Antiviral compounds and methods of making and using thereof
|
KR20120081164A
(ko)
|
2009-09-29 |
2012-07-18 |
엑스커버리 홀딩 컴퍼니 엘엘씨 |
Pi3k(델타) 선택적 억제제
|
US8106146B2
(en)
|
2009-10-06 |
2012-01-31 |
Medtronic, Inc. |
Therapeutic polymers and methods of generation
|
US8637543B2
(en)
|
2009-11-12 |
2014-01-28 |
Ucb Pharma S.A. |
Quinoline derivatives as kinase inhibitors
|
EP2499129B1
(en)
|
2009-11-12 |
2014-07-30 |
UCB Pharma, S.A. |
Quinoline and quinoxaline derivatives as kinase inhibitors
|
WO2011058109A1
(en)
|
2009-11-12 |
2011-05-19 |
Ucb Pharma S.A. |
Fused bicyclic pyrrole and imidazole derivatives as kinase inhibitors
|
AU2010319298B2
(en)
|
2009-11-13 |
2015-11-05 |
Plastipak Packaging, Inc. |
Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
|
JP2013512878A
(ja)
|
2009-12-03 |
2013-04-18 |
グラクソ グループ リミテッド |
新規化合物
|
AU2010327936B2
(en)
|
2009-12-11 |
2015-08-20 |
Nono Inc. |
Agents and methods for treating ischemic and other diseases
|
WO2011075628A1
(en)
|
2009-12-18 |
2011-06-23 |
Amgen Inc. |
Heterocyclic compounds and their uses
|
ES2842399T3
(es)
|
2009-12-22 |
2021-07-14 |
Vertex Pharma |
Inhibidores isoindolinona de fosfatidilinositol 3-quinasa
|
WO2011094890A1
(en)
|
2010-02-02 |
2011-08-11 |
Argusina Inc. |
Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
|
EP2536275A1
(en)
|
2010-02-16 |
2012-12-26 |
UWM Research Foundation, Inc. |
Methods of reducing virulence in bacteria
|
WO2011111880A1
(ko)
|
2010-03-08 |
2011-09-15 |
주식회사 메디젠텍 |
세포핵에서 세포질로의 gsk3의 이동을 억제하는 화합물을 함유하는 세포핵에서 세포질로의 gsk3 이동에 의해 발생되는 질환의 치료 또는 예방용 약학적 조성물
|
CN102206172B
(zh)
|
2010-03-30 |
2015-02-25 |
中国医学科学院医药生物技术研究所 |
一组取代双芳基化合物及其制备方法和抗病毒应用
|
WO2011133729A2
(en)
|
2010-04-23 |
2011-10-27 |
Kineta, Inc. |
Anti-viral compounds
|
US8927561B2
(en)
|
2010-04-23 |
2015-01-06 |
Kineta, Inc. |
Pyrimidinedione anti-viral compounds
|
NZ603268A
(en)
|
2010-05-04 |
2015-02-27 |
Alkermes Pharma Ireland Ltd |
Process for synthesizing oxidized lactam compounds
|
ES2593256T3
(es)
|
2010-05-21 |
2016-12-07 |
Infinity Pharmaceuticals, Inc. |
Compuestos químicos, composiciones y métodos para las modulaciones de cinasas
|
NZ603789A
(en)
|
2010-05-26 |
2015-03-27 |
Sunovion Pharmaceuticals Inc |
Heteroaryl compounds and methods of use thereof
|
US20120142701A1
(en)
|
2010-05-28 |
2012-06-07 |
The University Of Hong Kong |
Compounds and methods for the treatment of proliferative diseases
|
KR101580714B1
(ko)
|
2010-06-03 |
2016-01-04 |
파마싸이클릭스 엘엘씨 |
브루톤 티로신 인산화효소(btk)의 억제제의 용도
|
US20110306622A1
(en)
|
2010-06-11 |
2011-12-15 |
Calitoga Pharmaceuticals, Inc. |
Methods of treating hematological disorders with quinazolinone compounds in selected subjects
|
CA2803890A1
(en)
|
2010-06-25 |
2011-12-29 |
Rutgers, The State University Of New Jersey |
Antimicrobial agents
|
CN102971293A
(zh)
|
2010-07-05 |
2013-03-13 |
默克专利有限公司 |
用于治疗激酶诱导的疾病的联吡啶衍生物
|
US8906943B2
(en)
|
2010-08-05 |
2014-12-09 |
John R. Cashman |
Synthetic compounds and methods to decrease nicotine self-administration
|
AR082799A1
(es)
|
2010-09-08 |
2013-01-09 |
Ucb Pharma Sa |
Derivados de quinolina y quinoxalina como inhibidores de quinasa
|
US9670212B2
(en)
|
2010-09-14 |
2017-06-06 |
Exelixis, Inc. |
Inhibitors of PI3K-delta and methods of their use and manufacture
|
WO2012054332A1
(en)
|
2010-10-18 |
2012-04-26 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
EP2630136A1
(en)
|
2010-10-21 |
2013-08-28 |
Universität des Saarlandes |
Selective cyp11b1 inhibitors for the treatment of cortisol dependent diseases
|
WO2012061696A1
(en)
|
2010-11-04 |
2012-05-10 |
Amgen Inc. |
5 -cyano-4, 6 -diaminopyrimidine or 6 -aminopurine derivatives as pi3k- delta inhibitors
|
CA2817577A1
(en)
|
2010-11-10 |
2012-05-18 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
US20140066431A1
(en)
|
2010-11-15 |
2014-03-06 |
Exelixis, Inc. |
Benzoxazepines as Inhibitors of PI3K/mTOR and Methods of Their Use and Manufacture
|
EP2640366A2
(en)
|
2010-11-15 |
2013-09-25 |
Exelixis, Inc. |
Benzoxazepines as inhibitors of pi3k/mtor and methods of their use and manufacture
|
MX2013005826A
(es)
|
2010-11-24 |
2013-08-27 |
Exelixis Inc |
Benzoxazepinas como inhibidores de fosfatidilinositol 3-cinasa/objetivo de rapamicina en mamiferos (p13k/mtor) y metodos de uso y fabricacion.
|
US20140378436A9
(en)
|
2010-11-24 |
2014-12-25 |
Exelixis, Inc. |
Benzoxazepines as Inhibitors of PI3K/mTOR and Methods of Their use and Manufacture
|
DK2835131T3
(en)
|
2010-12-14 |
2017-12-04 |
Electrophoretics Ltd |
Casein kinase 1 delta inhibitors (CK1 delta)
|
US8765978B2
(en)
|
2010-12-16 |
2014-07-01 |
Transitions Optical, Inc. |
Method of making indeno-fused naphthol materials
|
WO2012088438A1
(en)
|
2010-12-22 |
2012-06-28 |
Eutropics Pharmaceuticals, Inc. |
Compositions and methods useful for treating diseases
|
UA115767C2
(uk)
|
2011-01-10 |
2017-12-26 |
Інфініті Фармасьютікалз, Інк. |
Способи отримання ізохінолінонів і тверді форми ізохінолінонів
|
US8791107B2
(en)
|
2011-02-25 |
2014-07-29 |
Takeda Pharmaceutical Company Limited |
N-substituted oxazinopteridines and oxazinopteridinones
|
US20140213630A1
(en)
|
2011-03-08 |
2014-07-31 |
Thomas Diacovo |
Methods and pharmaceutical compositions for treating lymphoid malignancy
|
EA201391263A1
(ru)
|
2011-03-11 |
2014-06-30 |
Джилид Калистога Ллс |
Комбинированные терапии гематологических опухолей
|
CA2830234A1
(en)
|
2011-03-15 |
2012-09-20 |
Abbvie Inc. |
Nuclear hormone receptor modulators
|
WO2012129562A2
(en)
|
2011-03-24 |
2012-09-27 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
CN102731492B
(zh)
|
2011-03-30 |
2016-06-29 |
江苏恒瑞医药股份有限公司 |
环己烷类衍生物、其制备方法及其在医药上的应用
|
CN103857395A
(zh)
|
2011-04-01 |
2014-06-11 |
基因泰克公司 |
Akt抑制剂化合物和阿比特龙的组合及使用方法
|
JO3733B1
(ar)
|
2011-04-05 |
2021-01-31 |
Bayer Ip Gmbh |
استخدام 3,2-دايهيدروايميدازو[1, 2 -c]كوينازولينات مستبدلة
|
KR101644051B1
(ko)
|
2011-05-20 |
2016-08-01 |
삼성전자 주식회사 |
광전자 소자 및 적층 구조
|
CN103635189B
(zh)
|
2011-07-01 |
2016-05-04 |
诺华股份有限公司 |
用于治疗癌症的含有cdk4/6抑制剂和pi3k抑制剂的联合治疗
|
US8969363B2
(en)
|
2011-07-19 |
2015-03-03 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
US9056877B2
(en)
|
2011-07-19 |
2015-06-16 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
WO2013013504A1
(zh)
|
2011-07-26 |
2013-01-31 |
山东亨利医药科技有限责任公司 |
替加环素衍生物
|
DK2738156T3
(en)
|
2011-07-26 |
2018-03-26 |
Kbp Biosciences Usa Inc |
9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS
|
CN103929959A
(zh)
|
2011-08-12 |
2014-07-16 |
萨克生物研究学院 |
神经保护性多酚类似物
|
PE20141371A1
(es)
|
2011-08-29 |
2014-10-13 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos y usos de los mismos
|
WO2013066483A1
(en)
|
2011-08-31 |
2013-05-10 |
Novartis Ag |
Synergistic combinations of pi3k- and mek-inhibitors
|
WO2013044169A1
(en)
|
2011-09-21 |
2013-03-28 |
Nestec S.A. |
Methods for determining combination therapy with il-2 for the treatment of cancer
|
CN110801454A
(zh)
|
2011-10-19 |
2020-02-18 |
药品循环有限责任公司 |
布鲁顿酪氨酸激酶(btk)抑制剂的用途
|
WO2013074583A1
(en)
|
2011-11-14 |
2013-05-23 |
The Broad Institute, Inc. |
Treatment and prognosis of lymphangioleiomyomatosis
|
WO2013086131A1
(en)
|
2011-12-06 |
2013-06-13 |
The Trustees Of The University Of Pennsylvania |
Inhibitors targeting drug-resistant influenza a
|
US8772541B2
(en)
|
2011-12-15 |
2014-07-08 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Cannabinoid receptor 2 (CB2) inverse agonists and therapeutic potential for multiple myeloma and osteoporosis bone diseases
|
US20150011569A1
(en)
|
2011-12-15 |
2015-01-08 |
Philadelphia Health & Education Corporation D/B/A Drexel University College Of Medicine |
NOVEL P13K p110 INHIBITORS AND METHODS OF USE THEREOF
|
TWI573792B
(zh)
|
2012-02-01 |
2017-03-11 |
歐陸斯迪公司 |
新穎治療劑
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
EP2861256B1
(en)
|
2012-06-15 |
2019-10-23 |
The Brigham and Women's Hospital, Inc. |
Compositions for treating cancer and methods for making the same
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
CN104704129A
(zh)
|
2012-07-24 |
2015-06-10 |
药品循环公司 |
与对布鲁顿酪氨酸激酶(btk)抑制剂的抗性相关的突变
|
US8673972B2
(en)
|
2012-08-03 |
2014-03-18 |
Foundation Medicine, Inc. |
Human papilloma virus as predictor of cancer prognosis
|
WO2014046617A1
(en)
|
2012-09-19 |
2014-03-27 |
Agency For Science, Technology And Research |
Compositions and methods for treating cancer
|
US20150283142A1
(en)
|
2013-03-15 |
2015-10-08 |
Infinity Pharmaceuticals, Inc. |
Treatment of cancers using pi3 kinase isoform modulators
|
US20140120060A1
(en)
|
2012-11-01 |
2014-05-01 |
Infinity Pharmaceuticals, Inc. |
Treatment of rheumatoid arthritis and asthma using pi3 kinase inhibitors
|
HUE040126T2
(hu)
|
2012-11-01 |
2019-02-28 |
Infinity Pharmaceuticals Inc |
Rákok kezelése PI3 kináz izoform modulátorok alkalmazásával
|
US20140120083A1
(en)
|
2012-11-01 |
2014-05-01 |
Infinity Pharmaceuticals, Inc. |
Treatment of cancers using pi3 kinase isoform modulators
|
SI3150256T1
(sl)
|
2012-11-02 |
2021-03-31 |
Tg Therapeutics Inc. |
Kombinacija anti-CD20 protitelesa in selektivnega inhibitorja PI3 kinaze
|
KR20210010958A
(ko)
|
2012-11-08 |
2021-01-28 |
리젠 파마슈티컬스 소시에떼 아노님 |
Pde4 억제제 및 pi3 델타 또는 이중 pi3 델타-감마 키나아제 억제제를 함유하는 약제학적 조성물
|
CA2891013A1
(en)
|
2012-11-16 |
2014-05-22 |
Abdelghani Abe Achab |
Purine inhibitors of human phosphatidylinositol 3-kinase delta
|
EP2953950B1
(en)
|
2013-02-11 |
2021-01-13 |
The Regents of The University of California |
Compositions and methods for treating neurodegenerative diseases
|
NZ629037A
(en)
|
2013-03-15 |
2017-04-28 |
Infinity Pharmaceuticals Inc |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
JP2016517404A
(ja)
|
2013-03-15 |
2016-06-16 |
ユニベルシテ ドゥ ジュネーブ |
インスリン産生の誘導方法およびその使用
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
JP6575952B2
(ja)
|
2013-04-08 |
2019-09-18 |
ファーマサイクリックス エルエルシー |
イブルチニブ併用療法
|
JP6227889B2
(ja)
|
2013-04-23 |
2017-11-08 |
関東化學株式会社 |
新規な有機金属錯体およびアミン化合物の製造方法
|
BR112015029969A2
(pt)
|
2013-05-30 |
2017-07-25 |
Infinity Pharmaceuticals Inc |
tratamento de câncer usando moduladores de isoformas quinase pi3
|
EP3007556B1
(en)
|
2013-06-13 |
2020-05-20 |
Biomatrica, INC. |
Cell stabilization
|
SI3008053T1
(en)
|
2013-06-14 |
2018-06-29 |
Gilead Calistoga Llc |
PHOSPHATIDYLINOSITOL 3-KINATE INHIBITORS
|
PT3012327T
(pt)
|
2013-06-20 |
2021-01-22 |
Taiho Pharmaceutical Co Ltd |
Método para prever a eficácia terapêutica do inibidor de pi3k/akt/mtor com base na expressão de phlda1 ou pik3c2b
|
UY35675A
(es)
|
2013-07-24 |
2015-02-27 |
Novartis Ag |
Derivados sustituidos de quinazolin-4-ona
|
US20150065431A1
(en)
|
2013-08-27 |
2015-03-05 |
Northwestern University |
Reducing cutaneous scar formation and treating skin conditions
|
US20160272707A1
(en)
|
2013-09-11 |
2016-09-22 |
Compugen Ltd. |
Vstm5 antibodies, and uses thereof for treatment of cancer, infectious diseases and immune related diseases
|
WO2015051252A1
(en)
|
2013-10-03 |
2015-04-09 |
Duke University |
Compositions and methods for treating cancer with jak2 activity
|
WO2015051241A1
(en)
|
2013-10-04 |
2015-04-09 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
EA201690713A1
(ru)
|
2013-10-04 |
2016-08-31 |
Инфинити Фармасьютикалз, Инк. |
Гетероциклические соединения и их применения
|
US9403779B2
(en)
|
2013-10-08 |
2016-08-02 |
Acetylon Pharmaceuticals, Inc. |
Combinations of histone deacetylase inhibitors and either Her2 inhibitors or PI3K inhibitors
|
JP6584391B2
(ja)
|
2013-10-10 |
2019-10-02 |
アセチロン ファーマシューティカルズ インコーポレイテッドAcetylon Pharmaceuticals,Inc. |
非ホジキンリンパ腫を治療するための、hdac阻害剤単独またはpi3k阻害剤との組み合わせ
|
US20160244452A1
(en)
|
2013-10-21 |
2016-08-25 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
EP3074016A2
(en)
|
2013-11-26 |
2016-10-05 |
Gilead Sciences, Inc. |
Therapies for treating myeloproliferative disorders
|
BR112016012794A2
(pt)
|
2013-12-05 |
2017-08-08 |
Acerta Pharma Bv |
Combinação terapêutica de um inibidor de pi3k e um inibidor de btk
|
JP6678585B2
(ja)
|
2013-12-20 |
2020-04-22 |
バイオメッド バレー ディスカバリーズ,インコーポレイティド |
Erk阻害剤およびraf阻害剤の組み合わせを使用するがん処置
|
AU2014368912B2
(en)
|
2013-12-20 |
2020-04-30 |
Biomed Valley Discoveries, Inc. |
Cancer treatments using combinations of type 2 MEK and ERK inhibitors
|
WO2015095831A1
(en)
|
2013-12-20 |
2015-06-25 |
Biomed Valley Discoveries, Inc. |
Cancer treatments using combinations of mtor and erk inhibitors
|
JP6678584B2
(ja)
|
2013-12-20 |
2020-04-22 |
バイオメッド バレー ディスカバリーズ,インコーポレイティド |
Cdk阻害剤およびerk阻害剤の組み合わせを使用するがん処置
|
WO2015095807A1
(en)
|
2013-12-20 |
2015-06-25 |
Biomed Valley Discoveries, Inc. |
Cancer treatments using combinations of egfr and erk inhibitors
|
US11007183B2
(en)
|
2013-12-20 |
2021-05-18 |
Biomed Valley Discoveries, Inc. |
Cancer treatments using combinations of PI3K/Akt pathway and ERK inhibitors
|
WO2015095834A2
(en)
|
2013-12-20 |
2015-06-25 |
Biomed Valley Discoveries, Inc. |
Cancer treatments using erk1/2 and bcl-2 family inhibitors
|
WO2015095842A2
(en)
|
2013-12-20 |
2015-06-25 |
Biomed Valley Discoveries, Inc. |
Methods and compositions for treating non-erk mapk pathway inhibitor-resistant cancers
|
AU2014368925A1
(en)
|
2013-12-20 |
2016-07-21 |
Biomed Valley Discoveries, Inc. |
Cancer treatments using combinations of MEK type I and ERK inhibitors
|
US20160331754A1
(en)
|
2014-01-20 |
2016-11-17 |
Gilead Sciences, Inc. |
Therapies for treating cancers
|
DK3119397T3
(da)
|
2014-03-19 |
2022-03-28 |
Infinity Pharmaceuticals Inc |
Heterocykliske forbindelser til anvendelse i behandling af PI3K-gamma-medierede lidelser
|
CN110841074B
(zh)
|
2014-03-21 |
2023-07-18 |
艾伯维公司 |
抗-egfr抗体及抗体药物偶联物
|
US20150320754A1
(en)
|
2014-04-16 |
2015-11-12 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
WO2015160975A2
(en)
|
2014-04-16 |
2015-10-22 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
WO2015175966A1
(en)
|
2014-05-16 |
2015-11-19 |
Memorial Sloan Kettering Cancer Center |
Platelet-derived growth factor receptor mutations and compositions and methods relating thereto
|
WO2015179772A1
(en)
|
2014-05-23 |
2015-11-26 |
Concert Pharmaceuticals, Inc. |
Deuterated phenylquinazolinone and phenylisoquinolinone compounds
|
MD20160138A2
(ro)
|
2014-05-27 |
2017-05-31 |
Almirall S.A. |
Combinaţie
|
ES2846811T3
(es)
|
2014-06-06 |
2021-07-29 |
Bluebird Bio Inc |
Composiciones de células T mejoradas
|
US9708348B2
(en)
|
2014-10-03 |
2017-07-18 |
Infinity Pharmaceuticals, Inc. |
Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
|
US20170209574A1
(en)
|
2014-10-03 |
2017-07-27 |
Novartis Ag |
Combination therapies
|
AU2016322552B2
(en)
|
2015-09-14 |
2021-03-25 |
Infinity Pharmaceuticals, Inc. |
Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
|
WO2017161116A1
(en)
|
2016-03-17 |
2017-09-21 |
Infinity Pharmaceuticals, Inc. |
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
|