|
AU784012B2
(en)
*
|
1999-08-24 |
2006-01-12 |
E. R. Squibb & Sons, L.L.C. |
Human CTLA-4 antibodies and their uses
|
|
US7605238B2
(en)
*
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
KR20120011898A
(ko)
|
2000-02-10 |
2012-02-08 |
아보트 러보러터리즈 |
사람 인터류킨-１８에 결합하는 항체 및 이를 제조하고 사용하는 방법
|
|
US7981420B2
(en)
|
2000-12-22 |
2011-07-19 |
Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. |
Therapeutic use of antibodies directed against repulsive guidance molecule (RGM)
|
|
SV2007000775A
(es)
|
2001-01-05 |
2007-03-15 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina
|
|
RS20110024A
(sr)
|
2001-04-26 |
2011-08-31 |
Biogen Idec Ma Inc. |
Antitela koja blokiraju cripto i njihova upotreba
|
|
CA2447114A1
(en)
|
2001-05-16 |
2002-11-21 |
Abgenix, Inc. |
Human antipneumococcal antibodies from non-human animals
|
|
IL149701A0
(en)
*
|
2001-05-23 |
2002-11-10 |
Pfizer Prod Inc |
Use of anti-ctla-4 antibodies
|
|
ES2675735T3
(es)
*
|
2001-06-26 |
2018-07-12 |
Amgen Inc. |
Anticuerpos para OPGL
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
AU2006228095B2
(en)
*
|
2001-10-11 |
2010-11-04 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
DE60328195D1
(de)
|
2002-03-29 |
2009-08-13 |
Schering Corp |
Menschliche monoklonale antikörper gegen interleukin-5 sowie diese umfassende verfahren und zusammensetzungen
|
|
US7452535B2
(en)
*
|
2002-04-12 |
2008-11-18 |
Medarex, Inc. |
Methods of treatment using CTLA-4 antibodies
|
|
AU2003260871A1
(en)
*
|
2002-09-30 |
2004-04-19 |
Pfizer Products Inc. |
Hybridomas producing high levels of human sequence antibody
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US7465446B2
(en)
|
2003-05-30 |
2008-12-16 |
Medarex, Inc. |
Surrogate therapeutic endpoint for anti-CTLA4-based immunotherapy of disease
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
US7273610B2
(en)
|
2003-08-14 |
2007-09-25 |
Dyax Corp. |
Endotheliase-2 ligands
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
US20050100965A1
(en)
|
2003-11-12 |
2005-05-12 |
Tariq Ghayur |
IL-18 binding proteins
|
|
AR047372A1
(es)
|
2004-01-09 |
2006-01-18 |
Pfizer |
Anticuerpos contra madcam
|
|
AU2005225227A1
(en)
*
|
2004-03-26 |
2005-10-06 |
Pfizer Products Inc. |
Uses of anti-CTLA-4 antibodies
|
|
US7494779B2
(en)
|
2004-06-14 |
2009-02-24 |
Li-Te Chin |
Method for producing human antibodies to human CD152 with properties of agonist, antagonist, or inverse agonist
|
|
CN1997670B
(zh)
|
2004-07-01 |
2014-04-30 |
诺和诺德公司 |
人类抗-kir抗体
|
|
JP2008506681A
(ja)
|
2004-07-16 |
2008-03-06 |
ファイザー・プロダクツ・インク |
抗ｉｇｆ−１ｒ抗体を用いる非血液性の悪性腫瘍の併用療法
|
|
WO2006056464A2
(en)
*
|
2004-11-26 |
2006-06-01 |
Pieris Ag |
Compound with affinity for the cytotoxic t lymphocyte-associated antigen (ctla-4)
|
|
HUE028410T2
(en)
*
|
2005-03-08 |
2016-12-28 |
Pfizer Prod Inc |
Anti-ctla-4 antibody compositions
|
|
AU2014240252B2
(en)
*
|
2005-03-08 |
2016-10-06 |
Pfizer Products Inc |
Anti-CTLA-4 Antibody Compositions
|
|
AU2012200203B2
(en)
*
|
2005-03-08 |
2014-07-03 |
Pfizer Products Inc. |
Anti-CTLA-4 Antibody Compositions
|
|
JP2006265155A
(ja)
*
|
2005-03-23 |
2006-10-05 |
Link Genomics Kk |
癌の免疫療法
|
|
MX2007010603A
(es)
*
|
2005-03-23 |
2007-10-18 |
Pfizer Prod Inc |
Terapia de cancer de prostata con anticuerpos contra ctla4 y terapia hormonal.
|
|
DK1866339T3
(da)
|
2005-03-25 |
2013-09-02 |
Gitr Inc |
GTR-bindende molekyler og anvendelser heraf
|
|
EP1877075A4
(de)
|
2005-04-25 |
2008-07-30 |
Pfizer |
Antikörper gegen myostatin
|
|
MX2007013304A
(es)
|
2005-04-26 |
2007-12-13 |
Pfizer |
Anticuerpos de p-caderina.
|
|
WO2006117910A1
(ja)
|
2005-04-28 |
2006-11-09 |
Mochida Pharmaceutical Co., Ltd. |
抗血小板膜糖蛋白質ⅵモノクローナル抗体
|
|
JP5224707B2
(ja)
*
|
2005-04-28 |
2013-07-03 |
持田製薬株式会社 |
抗血小板膜糖蛋白質ｖｉモノクローナル抗体
|
|
JP4361545B2
(ja)
|
2005-05-09 |
2009-11-11 |
小野薬品工業株式会社 |
ＰｒｏｇｒａｍｍｅｄＤｅａｔｈ１（ＰＤ−１）に対するヒトモノクローナル抗体および抗ＰＤ−１抗体単独または他の免疫療法と併用した癌治療方法
|
|
KR101804078B1
(ko)
|
2005-06-08 |
2017-12-01 |
다나-파버 캔서 인스티튜트 인크. |
예정 세포사 1(ｐｄ-1) 경로를 억제함으로써 지속 감염 및 암을 치료하기 위한 방법 및 조성물
|
|
AU2006269555A1
(en)
*
|
2005-07-07 |
2007-01-18 |
Coley Pharmaceutical Group, Inc. |
Anti-CTLA-4 antibody and CpG-motif-containing synthetic oligodeoxynucleotide combination therapy for cancer treatment
|
|
CN100443503C
(zh)
*
|
2005-07-18 |
2008-12-17 |
四川大学华西医院 |
人源化ctla-4单链抗体与人穿孔素通道形成肽p34的重组免疫毒素
|
|
EP2500354A3
(de)
|
2005-08-19 |
2012-10-24 |
Abbott Laboratories |
Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
|
|
CA2618482C
(en)
|
2005-08-19 |
2014-10-07 |
Abbott Laboratories |
Dual variable domain immunoglobin and uses thereof
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
PL2447283T3
(pl)
|
2005-09-07 |
2015-12-31 |
Amgen Fremont Inc |
Ludzkie przeciwciała monoklonalne przeciwko kinazie podobnej do receptora aktywiny-1 (ALK-1)
|
|
US7700567B2
(en)
|
2005-09-29 |
2010-04-20 |
Supergen, Inc. |
Oligonucleotide analogues incorporating 5-aza-cytosine therein
|
|
CN101277974A
(zh)
|
2005-09-30 |
2008-10-01 |
阿伯特有限及两合公司 |
排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
|
|
US7611702B2
(en)
|
2005-11-08 |
2009-11-03 |
Medarex, Inc. |
TNF-alpha blocker treatment for enterocolitis associated with immunostimulatory therapeutic antibody therapy
|
|
PT2289909E
(pt)
|
2005-11-30 |
2015-02-10 |
Abbvie Inc |
Método de rastreio, processo de purificação de globulómeros a-beta não difundíveis, anticorpos selectivos contra os referidos globulómeros a-beta não difundíveis e processo para o fabrico dos referidos anticorpos
|
|
PL1976877T5
(pl)
|
2005-11-30 |
2017-09-29 |
Abbvie Inc |
Przeciwciała monoklonalne przeciwko białku amyloidu beta oraz ich zastosowania
|
|
US8110194B2
(en)
|
2005-12-07 |
2012-02-07 |
Medarex, Inc. |
CTLA-4 antibody dosage escalation regimens
|
|
US8216996B2
(en)
|
2006-03-03 |
2012-07-10 |
Ono Pharmaceutical Co., Ltd. |
Multimer of extracellular domain of cell surface functional molecule
|
|
EP2013348A4
(de)
|
2006-03-30 |
2009-09-02 |
Univ California |
Verfahren und zusammensetzungen für lokalisierte sekretion von anti-ctla-4-antikörpern
|
|
US7919079B2
(en)
*
|
2006-03-31 |
2011-04-05 |
Biosante Pharmaceuticals, Inc. |
Cancer immunotherapy compositions and methods of use
|
|
EP2010567A2
(de)
|
2006-04-07 |
2009-01-07 |
The Government of the United States of America as Represented by The Department of Health and Human Services |
Antikörperzusammensetzungen und verfahren zur behandlung von neoplasien
|
|
SI2511301T1
(en)
|
2006-08-04 |
2018-05-31 |
MedImmune Limited, |
Human antibodies to ERBB 2
|
|
KR101625961B1
(ko)
|
2006-09-08 |
2016-05-31 |
애브비 바하마스 리미티드 |
인터루킨-13 결합 단백질
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
WO2008104386A2
(en)
|
2007-02-27 |
2008-09-04 |
Abbott Gmbh & Co. Kg |
Method for the treatment of amyloidoses
|
|
WO2008112193A1
(en)
|
2007-03-12 |
2008-09-18 |
Dana-Farber Cancer Institute |
Prognostic, diagnostic, and cancer therapeutic uses of fanci and fanci modulating agents
|
|
PE20081899A1
(es)
|
2007-04-02 |
2009-01-26 |
Pfizer |
Anticuerpos anti-ige
|
|
PT2175884T
(pt)
|
2007-07-12 |
2016-09-21 |
Gitr Inc |
Terapias de combinação empregando moléculas de ligação a gitr
|
|
EP2205249B1
(de)
|
2007-09-28 |
2018-11-07 |
Intrexon Corporation |
Therapeutische genschalterkonstrukte und bioreaktoren zur expression biotherapeutischer moleküle und ihre verwendung
|
|
RU2506275C2
(ru)
|
2007-11-01 |
2014-02-10 |
Астеллас Фарма Инк. |
Иммуносупрессорные полипептиды и нуклеиновые кислоты
|
|
PT2851374T
(pt)
|
2007-12-14 |
2017-06-20 |
Pfizer |
Moléculas de ligação ao recetor humano ox40
|
|
EP2962731A1
(de)
|
2008-01-08 |
2016-01-06 |
Bristol-Myers Squibb Company |
Kombination aus ipilimumab und paclitaxel zur behandlung von krebs
|
|
EP2240204A1
(de)
*
|
2008-02-04 |
2010-10-20 |
Medarex, Inc. |
Anti-clta-4-antikörper mit reduzierter blockierung der bindung von ctla-4 an b7 und verwendungen dafür
|
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
AU2009241589B2
(en)
|
2008-04-29 |
2013-10-10 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
EP3059248A1
(de)
|
2008-05-09 |
2016-08-24 |
Abbvie Deutschland GmbH & Co. KG |
Antikörper zu rezeptor für endprodukte der fortgeschrittenen glykierung (rage) und verwendungen davon
|
|
NZ589434A
(en)
|
2008-06-03 |
2012-11-30 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
EP2297208A4
(de)
|
2008-06-03 |
2012-07-11 |
Abbott Lab |
Dual-variable- domain-immunglobuline und ihre verwendungen
|
|
RU2559525C2
(ru)
|
2008-07-08 |
2015-08-10 |
Эббви Инк |
Белки, связывающие простагландин е2, и их применение
|
|
MX2010014574A
(es)
|
2008-07-08 |
2011-04-27 |
Abbott Lab |
Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas.
|
|
WO2010014784A2
(en)
|
2008-08-01 |
2010-02-04 |
Bristol-Myers Squibb Company |
Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
CN102239180B
(zh)
|
2008-08-18 |
2014-12-31 |
辉瑞大药厂 |
抗ccr2抗体
|
|
KR101012267B1
(ko)
*
|
2008-08-29 |
2011-02-08 |
주식회사 세이프로드 |
파손이 방지되는 차선규제봉 및 차선규제봉 시공방법
|
|
WO2010042433A1
(en)
|
2008-10-06 |
2010-04-15 |
Bristol-Myers Squibb Company |
Combination of cd137 antibody and ctla-4 antibody for the treatment of proliferative diseases
|
|
DK3059337T3
(da)
|
2009-01-15 |
2019-07-22 |
Adaptive Biotechnologies Corp |
Adaptive immunity profiling og metoder til frembringelse af monoklonale antibodier
|
|
EP3235509A1
(de)
|
2009-03-05 |
2017-10-25 |
AbbVie Inc. |
Il-17-bindende proteine
|
|
US8283162B2
(en)
|
2009-03-10 |
2012-10-09 |
Abbott Laboratories |
Antibodies relating to PIVKAII and uses thereof
|
|
EP2947098B1
(de)
|
2009-07-20 |
2019-11-20 |
Bristol-Myers Squibb Company |
Kombination aus einem anti-ctla4-antikörper und gemcitabine zur synergistischen behandlung proliferativer erkrankungen
|
|
BR112012004546A8
(pt)
|
2009-08-29 |
2017-12-05 |
Abbott Lab |
Terapêutica por proteínas ligantes dll4-ligantes
|
|
BR112012004710A2
(pt)
|
2009-09-01 |
2016-08-16 |
Abbott Lab |
imunoglobulinas de domínio variável duplo e uso das mesmas
|
|
CA2777226A1
(en)
|
2009-10-12 |
2011-04-21 |
Pfizer Inc. |
Cancer treatment
|
|
PH12012500691A1
(en)
|
2009-10-15 |
2012-11-12 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
WO2011053707A1
(en)
|
2009-10-31 |
2011-05-05 |
Abbott Laboratories |
Antibodies to receptor for advanced glycation end products (rage) and uses thereof
|
|
MX2012006560A
(es)
|
2009-12-08 |
2012-10-05 |
Abbott Gmbh & Co Kg |
Anticuerpos monoclonales contra la proteina rgm a para utilizarse en el tratamiento de degeneracion de capa de fibra de nervio retinal.
|
|
SG10201501562VA
(en)
|
2010-03-02 |
2015-04-29 |
Abbvie Inc |
Therapeutic dll4 binding proteins
|
|
CA2796339C
(en)
|
2010-04-15 |
2020-03-31 |
Abbott Laboratories |
Amyloid-beta binding proteins
|
|
AU2011252883B2
(en)
|
2010-05-14 |
2015-09-10 |
Abbvie Inc. |
IL-1 binding proteins
|
|
EP2571577A1
(de)
|
2010-05-17 |
2013-03-27 |
Bristol-Myers Squibb Company |
Verbesserte immuntherapeutische dosierpläne und kombinationen daraus
|
|
WO2012006500A2
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
US9120862B2
(en)
|
2010-07-26 |
2015-09-01 |
Abbott Laboratories |
Antibodies relating to PIVKA-II and uses thereof
|
|
AR082461A1
(es)
|
2010-08-03 |
2012-12-12 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
MX358739B
(es)
|
2010-08-14 |
2018-09-03 |
Abbvie Inc Star |
Proteinas de union a amiloide beta.
|
|
ES2910305T3
(es)
|
2010-08-19 |
2022-05-12 |
Zoetis Belgium S A |
Anticuerpos anti-NGF y su uso
|
|
MX2013002270A
(es)
|
2010-08-26 |
2013-05-14 |
Abbvie Inc |
Inmonoglubinas de dominio variable doble y usos de las mismas.
|
|
DK2646552T3
(en)
*
|
2010-12-02 |
2017-10-23 |
Pieris Pharmaceuticals Gmbh |
MUTEINES OF HUMAN LIPOCALIN 2 WITH AFFINITY FOR CTLA-4
|
|
KR101781546B1
(ko)
|
2010-12-14 |
2017-09-26 |
내셔널 유니버시티 오브 싱가포르 |
뎅기 바이러스 세로타입 1 e 프로틴에 특이적인 인간 단일클론 항체 및 그들의 용도
|
|
TW201307388A
(zh)
|
2010-12-21 |
2013-02-16 |
Abbott Lab |
Ｉｌ－１結合蛋白
|
|
US8853365B2
(en)
|
2010-12-21 |
2014-10-07 |
Abbvie Inc. |
Dual variable domain immunnoglobulins and uses thereof
|
|
GB201103955D0
(en)
*
|
2011-03-09 |
2011-04-20 |
Antitope Ltd |
Antibodies
|
|
WO2012142164A1
(en)
|
2011-04-12 |
2012-10-18 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
|
|
BR112013032630B1
(pt)
|
2011-06-30 |
2022-06-14 |
Chugai Seiyaku Kabushiki Kaisha |
Polipeptídeo heterodimerizado compreendendo região fc de igg
|
|
HK1198328A1
(zh)
|
2011-07-13 |
2015-04-02 |
Abbvie Inc. |
使用抗il-13抗體治療哮喘的方法和組合物
|
|
WO2013013029A1
(en)
*
|
2011-07-19 |
2013-01-24 |
The Board Of Trustees Of The University Of Illinois |
Anti-clta4, anti-glut2 protein for the treatment of type 1 diabetes
|
|
LT2750768T
(lt)
|
2011-08-30 |
2019-02-11 |
Astex Pharmaceuticals, Inc. |
Decitabino darinio kompozicijos
|
|
AU2012328921B2
(en)
|
2011-10-24 |
2017-05-11 |
Abbvie Inc. |
Immunobinders directed against TNF
|
|
TW201323440A
(zh)
|
2011-10-24 |
2013-06-16 |
Abbvie Inc |
抗骨硬化素（ｓｃｌｅｒｏｓｔｉｎ）之免疫結合物
|
|
IN2014CN04183A
(de)
|
2011-11-08 |
2015-07-17 |
Pfizer |
|
|
CA3204283A1
(en)
|
2011-12-14 |
2013-06-20 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
|
US9636398B2
(en)
|
2011-12-14 |
2017-05-02 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
|
UY34558A
(es)
|
2011-12-30 |
2013-07-31 |
Abbvie Inc |
Proteínas de unión específicas duales dirigidas contra il-13 y/o il-17
|
|
CN107880124B
(zh)
|
2012-01-27 |
2021-08-13 |
艾伯维德国有限责任两合公司 |
用于诊断和治疗与神经突变性相关的疾病的组合物和方法
|
|
WO2013138702A2
(en)
|
2012-03-15 |
2013-09-19 |
Bristol-Myers Squibb Company |
Methods for predicting gastrointestinal immune-related adverse events (gi-irae) in patients treated with modulation of the co-stimulatory pathway
|
|
US20150079100A1
(en)
|
2012-03-23 |
2015-03-19 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla-4 antibodies
|
|
WO2013155447A1
(en)
|
2012-04-13 |
2013-10-17 |
Children's Medical Center Corporation |
Tiki inhibitors
|
|
KR102125658B1
(ko)
|
2012-05-04 |
2020-06-22 |
화이자 인코포레이티드 |
전립선 관련된 항원 및 백신 기재 면역치료 요법
|
|
WO2013169971A1
(en)
|
2012-05-10 |
2013-11-14 |
Bristol-Myers Squibb Company |
Anti-tumor antibodies as predictive or prognostic biomarkers of efficacy and survival in ipilimumab-treated patients
|
|
SG10201700698WA
(en)
|
2012-05-15 |
2017-02-27 |
Bristol Myers Squibb Co |
Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
|
|
WO2013184871A1
(en)
|
2012-06-06 |
2013-12-12 |
Zoetis Llc |
Caninized anti-ngf antibodies and methods thereof
|
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
|
TW201402608A
(zh)
|
2012-07-12 |
2014-01-16 |
Abbvie Inc |
Ｉｌ－１結合蛋白質
|
|
CN105073132B
(zh)
*
|
2012-08-23 |
2020-01-10 |
艾更斯司股份有限公司 |
结合158p1d7蛋白的抗体药物偶联物(adc)
|
|
CA2890263C
(en)
|
2012-11-01 |
2020-03-10 |
Abbvie Inc. |
Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
|
|
US9550986B2
(en)
|
2012-12-21 |
2017-01-24 |
Abbvie Inc. |
High-throughput antibody humanization
|
|
LT2961388T
(lt)
|
2013-03-01 |
2019-08-26 |
Astex Pharmaceuticals, Inc. |
Vaistų deriniai
|
|
EP3564384A1
(de)
|
2013-03-14 |
2019-11-06 |
Abbott Laboratories |
Monoklonale antikörper gegen hcv-core lipid-bindender domäne
|
|
EP2970947A4
(de)
|
2013-03-14 |
2016-10-12 |
Abbott Lab |
Rekombinante hcv-ns3-antigene und mutanten für den verbesserten nachweis von antikörpern
|
|
CN105228649B
(zh)
|
2013-03-14 |
2019-01-18 |
雅培制药有限公司 |
Hcv抗原-抗体组合测定和方法以及用在其中的组合物
|
|
EP2970443A4
(de)
|
2013-03-14 |
2017-01-11 |
Parkash S. Gill |
Krebsbehandlung unter verwendung von antikörpern zur bindung von grp78 an die zelloberfläche
|
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
|
JP2016522793A
(ja)
|
2013-03-15 |
2016-08-04 |
アッヴィ・インコーポレイテッド |
ＩＬ−１βおよび／またはＩＬ−１７に対して指向された二重特異的結合タンパク質
|
|
CA2914566A1
(en)
|
2013-06-07 |
2014-12-11 |
Duke University |
Inhibitors of complement factor h
|
|
ES2760249T3
(es)
|
2013-08-08 |
2020-05-13 |
Cytune Pharma |
Composición farmacéutica combinada
|
|
HUE057598T2
(hu)
|
2013-08-08 |
2022-05-28 |
Cytune Pharma |
IL-15 és IL-15R-alfa sushi domén alapú modulokinek
|
|
DK3508502T5
(da)
|
2013-09-20 |
2024-09-02 |
Bristol Myers Squibb Co |
Kombination af anti-lag-3-antistoffer og anti-pd-1-antistoffer til behandling af tumorer
|
|
EP3524262A1
(de)
|
2013-11-01 |
2019-08-14 |
Pfizer Inc |
Vektoren zur expression von prostataassoziierten antigenen
|
|
ES2991853T3
(es)
|
2013-11-05 |
2024-12-05 |
Cognate Bioservices Inc |
Combinaciones de inhibidores del punto de control y terapéuticos para tratar el cáncer
|
|
WO2015069703A1
(en)
|
2013-11-06 |
2015-05-14 |
Bristol-Myers Squibb Company |
Immunotherapeutic dosing regimens and combinations thereof
|
|
AU2015205530B8
(en)
|
2014-01-13 |
2019-09-19 |
Pieris Pharmaceuticals Gmbh |
Multi-specific polypeptide useful for localized tumor immunomodulation
|
|
PH12016502345B1
(en)
|
2014-05-28 |
2023-03-01 |
Agenus Inc |
Anti-gitr antibodies and methods of use thereof
|
|
ES2901705T3
(es)
|
2014-06-06 |
2022-03-23 |
Bristol Myers Squibb Co |
Anticuerpos contra el receptor del factor de necrosis tumoral inducido por glucocorticoides (GITR) y usos de los mismos
|
|
CN105296433B
(zh)
*
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
|
WO2016033555A1
(en)
|
2014-08-28 |
2016-03-03 |
Halozyme, Inc. |
Combination therapy with a hyaluronan-degrading enzyme and an immune checkpoint inhibitor
|
|
US10759860B2
(en)
|
2014-09-16 |
2020-09-01 |
Synermore Biologics Co., Ltd. |
Anti-EGFR antibody and uses of same
|
|
MX391478B
(es)
|
2014-10-10 |
2025-03-21 |
Idera Pharmaceuticals Inc |
Composiciones de agonista de tlr9 e inhibidores de punto de control para usarse en la respuesta inmune contra el cáncer.
|
|
CN108064282A
(zh)
|
2014-10-14 |
2018-05-22 |
哈洛齐梅公司 |
腺苷脱氨酶-2(ada2)、其变体的组合物及使用其的方法
|
|
WO2016070769A1
(zh)
*
|
2014-11-04 |
2016-05-12 |
北京韩美药品有限公司 |
同时阻断b7/cd28和il6/il6r/gp130信号通路的重组融合蛋白
|
|
CN105597090B
(zh)
*
|
2014-11-14 |
2022-08-23 |
中国科学院上海营养与健康研究所 |
一种提高cd4阳性t淋巴细胞存活率和活性的试剂及其应用
|
|
RS60998B1
(sr)
|
2014-11-21 |
2020-11-30 |
Bristol Myers Squibb Co |
Antitela koja sadrže modifikovane regione teškog lanca
|
|
SI3221363T1
(sl)
|
2014-11-21 |
2020-09-30 |
Bristol-Myers Squibb Company |
Protitelesa proti CD73 in njihova uporaba
|
|
AU2015358462A1
(en)
|
2014-12-04 |
2017-07-27 |
Bristol-Myers Squibb Company |
Combination of anti-CS1 and anti-PD1 antibodies to treat cancer (myeloma)
|
|
CN104387453A
(zh)
*
|
2014-12-08 |
2015-03-04 |
深圳市同康生物医药有限公司 |
树突状细胞靶向肽及编码基因及应用
|
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
|
CA2971732A1
(en)
|
2014-12-23 |
2016-06-30 |
Bristol-Myers Squibb Company |
Antibodies to tigit
|
|
RS61470B1
(sr)
|
2014-12-31 |
2021-03-31 |
Checkmate Pharmaceuticals Inc |
Kombinovana antitumorska imunoterapija
|
|
US10983128B2
(en)
|
2015-02-05 |
2021-04-20 |
Bristol-Myers Squibb Company |
CXCL11 and SMICA as predictive biomarkers for efficacy of anti-CTLA4 immunotherapy
|
|
CN108271359B
(zh)
*
|
2015-02-13 |
2021-11-09 |
索伦托药业有限公司 |
结合ctla4的抗体治疗剂
|
|
WO2016146143A1
(en)
|
2015-03-16 |
2016-09-22 |
Amal Therapeutics Sa |
Cell penetrating peptides and complexes comprising the same
|
|
CA2981068C
(en)
|
2015-03-26 |
2021-12-14 |
Women & Infants Hospital Of Rhode Island |
Therapy for malignant disease comprising the inhibition of human epididymal secretory protein e4 and immune checkpoint inhibitors
|
|
US10842848B2
(en)
|
2015-04-07 |
2020-11-24 |
Cytlimic Inc. |
Method for treating cancer by adminstering poly I:C and LAG-3-IgG fusion protein
|
|
RU2017142352A
(ru)
|
2015-05-06 |
2019-06-06 |
Снипр Текнолоджиз Лимитед |
Изменение популяций микроорганизмов и модификация микробиоты
|
|
JP7028765B2
(ja)
|
2015-05-22 |
2022-03-02 |
トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー |
ベンズアミドおよび活性化合物組成物および使用方法
|
|
SG10202008304TA
(en)
|
2015-05-29 |
2020-10-29 |
Bristol Myers Squibb Co |
Antibodies against ox40 and uses thereof
|
|
SI3303395T1
(sl)
|
2015-05-29 |
2020-03-31 |
Abbvie Inc. |
Protitelesa proti CD40 in njihove uporabe
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
|
|
MX2017016502A
(es)
|
2015-06-29 |
2018-03-12 |
Univ Rockefeller |
Anticuerpos contra cd40 con actividad agonista mejorada.
|
|
LT3313528T
(lt)
|
2015-06-29 |
2021-10-11 |
Bristol-Myers Squibb Company |
Imunoterapinės dozavimo schemos, apimančios pomalidomidą ir anti-cs1 antikūną, skirtos vėžio gydymui
|
|
JP6768722B2
(ja)
|
2015-07-02 |
2020-10-14 |
大塚製薬株式会社 |
凍結乾燥医薬組成物
|
|
CN116196426A
(zh)
|
2015-07-16 |
2023-06-02 |
百欧肯治疗有限公司 |
治疗癌症的组合物及方法
|
|
RU2711380C2
(ru)
|
2015-07-16 |
2020-01-16 |
Байоксэл Терапьютикс, Инк. |
Новый подход к лечению рака с применением иммуномодуляции
|
|
WO2017021913A1
(en)
|
2015-08-04 |
2017-02-09 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
|
WO2017025871A1
(en)
|
2015-08-07 |
2017-02-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
|
EP4548979A3
(de)
|
2015-09-11 |
2025-07-23 |
Nascent Biotech, Inc. |
Verbesserte abgabe von medikamenten an das gehirn
|
|
ES2892972T3
(es)
|
2015-11-02 |
2022-02-07 |
Univ Texas |
Métodos de activación de CD40 y bloqueo de punto de control inmunitario
|
|
JP2019503985A
(ja)
|
2015-11-03 |
2019-02-14 |
グリコミメティクス， インコーポレイテッド |
モノクローナル抗体、造血幹細胞の産生のための方法および組成物、ならびにそれらを使用する方法
|
|
EP3371221A2
(de)
|
2015-11-07 |
2018-09-12 |
MultiVir Inc. |
Verfahren und zusammensetzungen mit tumorsuppressorgentherapie und immuncheckpoint-blockade zur behandlung von krebs
|
|
BR112018010172A2
(pt)
|
2015-11-19 |
2018-11-21 |
Bristol Myers Squibb Co |
anticorpos contra receptor de fator de necrose de tumor induzido por glicocorticoide (gitr) e usos dos mesmos
|
|
AU2016364889B2
(en)
|
2015-12-02 |
2024-01-04 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
SG11201804839WA
(en)
|
2015-12-14 |
2018-07-30 |
Macrogenics Inc |
Bispecific molecules having immunoreactivity with pd-1 and ctla-4, and methods of use thereof
|
|
MA43587A
(fr)
|
2016-01-10 |
2018-11-14 |
Modernatx Inc |
Arnm thérapeutiques codant pour des anticorps anti-ctla-4
|
|
KR20230038311A
(ko)
|
2016-03-04 |
2023-03-17 |
브리스톨-마이어스 스큅 컴퍼니 |
항-cd73 항체와의 조합 요법
|
|
WO2017160599A1
(en)
|
2016-03-14 |
2017-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Use of cd300b antagonists to treat sepsis and septic shock
|
|
US10947317B2
(en)
|
2016-03-15 |
2021-03-16 |
Mersana Therapeutics, Inc. |
NaPi2b-targeted antibody-drug conjugates and methods of use thereof
|
|
JP7189021B2
(ja)
|
2016-03-16 |
2022-12-13 |
アマル セラピューティクス エスエー |
医療において使用するための、免疫チェックポイントモジュレータと、細胞透過性ペプチド、カーゴ、及びｔｌｒペプチドアゴニストを含む複合体との組合せ
|
|
EP3436480A4
(de)
|
2016-03-30 |
2019-11-27 |
Musc Foundation for Research Development |
Verfahren zur behandlung und diagnose von krebs durch targeting von glycoprotein a repetitions predominant (garp) und zur effektiven immuntherapie allein oder in kombination
|
|
EP3436066A1
(de)
|
2016-04-01 |
2019-02-06 |
Checkmate Pharmaceuticals, Inc. |
Fc-rezeptor-vermittelte wirkstofffreisetzung
|
|
SG11201808821WA
(en)
|
2016-04-18 |
2018-11-29 |
Celldex Therapeutics Inc |
Agonistic antibodies that bind human cd40 and uses thereof
|
|
US11459617B2
(en)
|
2016-04-29 |
2022-10-04 |
Board Of Regents, The University Of Texas System |
Targeted measure of transcriptional activity related to hormone receptors
|
|
WO2017192874A1
(en)
|
2016-05-04 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Albumin-binding immunomodulatory compositions and methods of use thereof
|
|
AU2017268399B2
(en)
|
2016-05-18 |
2023-01-12 |
Modernatx, Inc. |
mRNA combination therapy for the treatment of cancer
|
|
EP3463448A4
(de)
|
2016-05-30 |
2020-03-11 |
Geovax Inc. |
Zusammensetzungen und verfahren zur erzeugung einer immunreaktion auf hepatitis-b-virus
|
|
US10994033B2
(en)
|
2016-06-01 |
2021-05-04 |
Bristol-Myers Squibb Company |
Imaging methods using 18F-radiolabeled biologics
|
|
GB201609811D0
(en)
|
2016-06-05 |
2016-07-20 |
Snipr Technologies Ltd |
Methods, cells, systems, arrays, RNA and kits
|
|
NZ789594A
(en)
|
2016-06-20 |
2025-07-25 |
Kymab Ltd |
Anti-PD-L1 antibodies
|
|
CA3029426A1
(en)
|
2016-06-30 |
2018-01-04 |
Oncorus, Inc. |
Pseudotyped oncolytic viral delivery of therapeutic polypeptides
|
|
AU2017297506A1
(en)
|
2016-07-14 |
2019-02-21 |
Bristol-Myers Squibb Company |
Antibodies against TIM3 and uses thereof
|
|
NL2017270B1
(en)
*
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
|
EP3494140A1
(de)
|
2016-08-04 |
2019-06-12 |
GlaxoSmithKline Intellectual Property Development Ltd |
Anti-icos- und anti-pd-1-antikörper-kombinationstherapie
|
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
|
DK3515476T3
(da)
|
2016-09-21 |
2024-09-02 |
Amal Therapeutics Sa |
Fusion der omfatter et cellepenetrerende peptid, en multiepitop og en trl-peptidagnost til behandlingen af cancer
|
|
BR112019006041A2
(pt)
|
2016-09-27 |
2019-09-03 |
Board Of Regents, The University Of Texas System |
métodos para aprimorar a terapia de bloqueio do ponto de verificação imunológico por modulação do microbioma
|
|
MX2019003474A
(es)
|
2016-10-03 |
2019-10-07 |
Abbott Lab |
Metodos mejorados para evaluar el estado de la proteina acidica fibrilar glial (gfap) en muestras de pacientes.
|
|
JP6976322B2
(ja)
*
|
2016-10-10 |
2021-12-08 |
クラウン バイオサイエンス，インコーポレイテッド（タイツァン） |
新規抗ｃｔｌａ４抗体
|
|
JP6998880B2
(ja)
|
2016-10-11 |
2022-02-10 |
サイトリミック株式会社 |
医薬
|
|
RU2755903C2
(ru)
|
2016-10-12 |
2021-09-22 |
Борд Оф Риджентс, Дзе Юниверсити Оф Техас Систем |
Способы и композиции для tusc2-иммунотерапии
|
|
KR102634093B1
(ko)
|
2016-10-28 |
2024-02-07 |
브리스톨-마이어스 스큅 컴퍼니 |
항-pd-1 항체를 사용하여 요로상피 암종을 치료하는 방법
|
|
WO2018089293A2
(en)
*
|
2016-11-08 |
2018-05-17 |
Qilu Puget Sound Biotherapeutics Corporation |
Anti-pd1 and anti-ctla4 antibodies
|
|
EP3538152A4
(de)
|
2016-11-09 |
2020-09-30 |
Agenus Inc. |
Anti-ox40-antikörper, anti-gitr-antikörper und verfahren zur verwendung davon
|
|
CA3043356A1
(en)
|
2016-11-09 |
2018-05-17 |
Musc Foundation For Research Development |
Cd38-nad+ regulated metabolic axis in anti-tumor immunotherapy
|
|
CA3044432A1
(en)
|
2016-11-17 |
2018-05-24 |
Board Of Regents, The University Of Texas System |
Compounds with anti-tumor activity against cancer cells bearing egfr or her2 exon 20 mutations
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
EP3544601B1
(de)
|
2016-11-23 |
2024-03-20 |
Translational Drug Development, LLC |
Eine zusammensetzung, die ein benzamid und einen tnfrsf-agonisten umfasst, der an 4-1bb oder gitr bindet, und die verwendung derselben bei der behandlung von krebs.
|
|
BR112019010878A2
(pt)
|
2016-11-29 |
2019-10-01 |
Lindhofer Horst |
combinação de anticorpos multifuncionais de redirecionamento de células t com moduladores de ponto de verificação imunológico e usos dos mesmos
|
|
CN110234342A
(zh)
|
2016-12-01 |
2019-09-13 |
葛兰素史密斯克莱知识产权发展有限公司 |
组合疗法
|
|
US20190343803A1
(en)
|
2016-12-01 |
2019-11-14 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
|
SG10201912575RA
(en)
|
2016-12-12 |
2020-02-27 |
Daiichi Sankyo Co Ltd |
Combination of antibody-drug conjugate and immune checkpoint inhibitor
|
|
KR20190112263A
(ko)
|
2016-12-12 |
2019-10-04 |
멀티비르 인코포레이티드 |
암 및 감염성 질환의 치료 및 예방을 위한 바이러스 유전자 치료요법 및 면역 체크포인트 억제제를 포함하는 방법 및 조성물
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
EP3585430A4
(de)
*
|
2017-02-21 |
2020-12-09 |
REMD Biotherapeutics, Inc. |
Krebsbehandlung unter verwendung von antikörpern, die zytotoxisches t-lymphozyt-antigen-4 (ctla-4) binden
|
|
EP3586136B1
(de)
|
2017-02-24 |
2023-11-08 |
Board Of Regents, The University Of Texas System |
Test zum nachweis von pankreaskarzinom im frühstadium
|
|
EP3366703B1
(de)
|
2017-02-28 |
2019-04-03 |
Ralf Kleef |
Immun kontrollpunkt therapie mit hyperthermie
|
|
US20180271996A1
(en)
|
2017-02-28 |
2018-09-27 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
|
WO2018167780A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of prognosing and treating cancer
|
|
WO2018167778A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of diagnosing and prognosing cancer
|
|
WO2018175942A1
(en)
|
2017-03-23 |
2018-09-27 |
Abbott Laboratories |
Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1
|
|
AU2018243754B2
(en)
|
2017-03-31 |
2025-04-10 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
EP3610268B1
(de)
|
2017-04-15 |
2025-09-24 |
Abbott Laboratories |
Verfahren zur unterstützung der diagnose und der bestimmung von traumatischen gehirnschäden bei menschen mithilfe frühen biomarkern
|
|
EP3615070A1
(de)
|
2017-04-26 |
2020-03-04 |
Bristol-Myers Squibb Company |
Verfahren zur antikörperproduktion mit minimaler disulfidbindungsreduzierung
|
|
US10877038B2
(en)
|
2017-04-28 |
2020-12-29 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
|
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
|
CN108948194B
(zh)
*
|
2017-05-19 |
2023-02-17 |
上海药明生物技术有限公司 |
一种新的ctla-4单克隆抗体
|
|
US11643463B2
(en)
*
|
2017-05-19 |
2023-05-09 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Monoclonal antibodies to cytotoxic T-lymphocyte-associated protein 4 (CTLA-4)
|
|
CN110651190A
(zh)
|
2017-05-25 |
2020-01-03 |
雅培实验室 |
用早期生物标记物帮助确定是否对已遭受或可能已遭受头部损伤的人受试者执行成像的方法
|
|
IL270596B1
(en)
|
2017-05-25 |
2025-09-01 |
Bristol Myers Squibb Co |
Antibodies comprising modified heavy constant region for use in treating cancer
|
|
JP7301002B2
(ja)
|
2017-05-30 |
2023-06-30 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗ｌａｇ－３抗体または抗ｌａｇ－３抗体および抗ｐｄ－１もしくは抗ｐｄ－ｌ１抗体を含む組成物
|
|
EP3631467A1
(de)
|
2017-05-30 |
2020-04-08 |
Abbott Laboratories |
Verfahren zur hilfe bei der diagnose und evaluierung einer leichten traumatischen hirnläsion bei einer person unter verwendung von herztroponin i
|
|
RS64787B1
(sr)
|
2017-05-30 |
2023-11-30 |
Bristol Myers Squibb Co |
Lečenje lag-3-pozitivnih tumora
|
|
CA3060989A1
(en)
|
2017-05-30 |
2018-12-06 |
Bristol-Myers Squibb Company |
Compositions comprising a combination of an anti-lag-3 antibody, a pd-1 pathway inhibitor, and an immunotherapeutic agent
|
|
JP7657023B2
(ja)
|
2017-06-09 |
2025-04-04 |
プロビデンス ヘルス アンド サービシーズ－オレゴン |
がんの処置のための腫瘍反応性ヒトｔ細胞の同定のためのｃｄ３９およびｃｄ１０３の使用
|
|
WO2019010131A1
(en)
|
2017-07-03 |
2019-01-10 |
Abbott Laboratories |
IMPROVED METHODS FOR MEASURING CARBOXY TERMINATION HYDROLASE LEVELS OF UBIQUITIN L1 IN BLOOD
|
|
MY201080A
(en)
|
2017-07-14 |
2024-02-03 |
Innate Tumor Immunity Inc |
Nlrp3 modulators
|
|
EP3652211A1
(de)
|
2017-07-14 |
2020-05-20 |
Pfizer Inc. |
Antikörper gegen madcam
|
|
TWI799432B
(zh)
*
|
2017-07-27 |
2023-04-21 |
美商再生元醫藥公司 |
抗ctla-4抗體及其用途
|
|
AU2018310857A1
(en)
|
2017-08-03 |
2020-02-13 |
Otsuka Pharmaceutical Co., Ltd. |
Drug compound and purification methods thereof
|
|
CN111511762B
(zh)
|
2017-08-21 |
2025-05-06 |
天演药业公司 |
抗cd137分子及其用途
|
|
CN111386117A
(zh)
|
2017-09-29 |
2020-07-07 |
百时美施贵宝公司 |
治疗癌症的组合物和方法
|
|
MX2020003806A
(es)
|
2017-10-06 |
2020-11-09 |
Wistar Inst |
Anticuerpos monoclonales de adn que se dirigen a ctla-4 para el tratamiento y prevención del cáncer.
|
|
WO2019075090A1
(en)
|
2017-10-10 |
2019-04-18 |
Tilos Therapeutics, Inc. |
ANTI-LAP ANTIBODIES AND USES THEREOF
|
|
US12178787B2
(en)
|
2017-10-12 |
2024-12-31 |
Board Of Regents, The University Of Texas System |
T cell receptors for immunotherapy
|
|
KR20200064132A
(ko)
|
2017-10-15 |
2020-06-05 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
KR20200074214A
(ko)
|
2017-11-01 |
2020-06-24 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하는데 사용하기 위한 면역자극 효능작용 항체
|
|
JP7339944B2
(ja)
|
2017-11-07 |
2023-09-06 |
ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム |
がんの処置におけるｃａｒ－ｔ細胞またはｃａｒ－ｎｋ細胞を用いるｌｉｌｒｂ４のターゲティング法
|
|
US11638760B2
(en)
|
2017-11-27 |
2023-05-02 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
CN108003238B
(zh)
*
|
2017-11-30 |
2021-02-02 |
常州费洛斯药业科技有限公司 |
一种能特异识别ctla-4的全人源单克隆抗体或抗体片段及其方法和用途
|
|
AU2018378971B9
(en)
|
2017-12-09 |
2025-04-17 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (TBI), using glial fibrillary acidic protein (GFAP) and/or ubiquitin carboxy-terminal hydrolase l1 (UCH-L1)
|
|
US11016105B2
(en)
|
2017-12-09 |
2021-05-25 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of GFAP and UCH-L1
|
|
WO2019120232A1
(en)
*
|
2017-12-20 |
2019-06-27 |
Harbour Biomed (Shanghai) Co., Ltd |
Antibodies binding ctla-4 and uses thereof
|
|
TW201929908A
(zh)
|
2017-12-21 |
2019-08-01 |
美商梅爾莎納醫療公司 |
吡咯并苯并二氮呯抗體共軛物
|
|
US11306149B2
(en)
|
2017-12-27 |
2022-04-19 |
Bristol-Myers Squibb Company |
Anti-CD40 antibodies and uses thereof
|
|
WO2019133847A1
(en)
|
2017-12-29 |
2019-07-04 |
Oncorus, Inc. |
Oncolytic viral delivery of therapeutic polypeptides
|
|
CN111886255B
(zh)
|
2018-01-12 |
2025-04-04 |
百时美施贵宝公司 |
抗tim3抗体及其用途
|
|
EA202091751A1
(ru)
|
2018-01-22 |
2020-11-06 |
Бристол-Маерс Сквибб Компани |
Композиции и способы лечения рака
|
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
|
EP3752194A4
(de)
|
2018-02-13 |
2022-03-16 |
Checkmate Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren für die tumorimmuntherapie
|
|
MX2020009526A
(es)
|
2018-03-12 |
2020-10-28 |
Zoetis Services Llc |
Anticuerpos anti-ngf y metodos de estos.
|
|
EP3765085A1
(de)
|
2018-03-12 |
2021-01-20 |
Université de Paris |
Verwendung von kalorienrestriktionsmimetika zur potenzierung der chemo-immuntherapie zur behandlung von krebserkrankungen
|
|
AU2019322487B2
(en)
|
2018-03-19 |
2024-04-18 |
Multivir Inc. |
Methods and compositions comprising tumor suppressor gene therapy and CD122/CD132 agonists for the treatment of cancer
|
|
EP3768721A4
(de)
*
|
2018-03-19 |
2021-12-29 |
Wuxi Biologics Ireland Limited. |
Neuartiges anti-ctla-4-antikörper-polypeptid
|
|
AU2019239747A1
(en)
|
2018-03-21 |
2020-10-08 |
Bristol-Myers Squibb Company |
Antibodies binding to VISTA at acidic pH
|
|
EP3768715A1
(de)
|
2018-03-23 |
2021-01-27 |
Bristol-Myers Squibb Company |
Antikörper gegen mica und/or micb und deren verwendungen
|
|
WO2019185551A1
(en)
|
2018-03-25 |
2019-10-03 |
Snipr Biome Aps. |
Treating & preventing microbial infections
|
|
US10760075B2
(en)
|
2018-04-30 |
2020-09-01 |
Snipr Biome Aps |
Treating and preventing microbial infections
|
|
SG11202009498RA
(en)
|
2018-03-27 |
2020-10-29 |
Univ Texas |
Compounds with anti-tumor activity against cancer cells bearing her2 exon 19 mutations
|
|
WO2019191676A1
(en)
|
2018-03-30 |
2019-10-03 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
US12084655B2
(en)
|
2018-04-09 |
2024-09-10 |
Checkmate Pharmaceuticals |
Packaging oligonucleotides into virus-like particles
|
|
EP3781596A1
(de)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Il-15/il-15ra-heterodimere fc-fusionsproteine und verwendungen davon
|
|
AU2019256539A1
(en)
|
2018-04-18 |
2020-11-26 |
Xencor, Inc. |
PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof
|
|
EP4353235A3
(de)
|
2018-04-25 |
2024-07-31 |
Innate Tumor Immunity, Inc. |
Nlrp3-modulatoren
|
|
EP3810109B1
(de)
|
2018-05-31 |
2024-08-07 |
Peloton Therapeutics, Inc. |
Verbindungen und zusammensetzungen zur hemmung von cd73
|
|
WO2019241358A2
(en)
|
2018-06-12 |
2019-12-19 |
The Regents Of The University Of California |
Single-chain bispecific chimeric antigen receptors for the treatment of cancer
|
|
EP3820904A2
(de)
|
2018-07-09 |
2021-05-19 |
Five Prime Therapeutics, Inc. |
An ilt4 bindende antikörper
|
|
BR112021000303A2
(pt)
|
2018-07-11 |
2021-04-13 |
Five Prime Therapeutics, Inc. |
Anticorpos que se ligam a vista em ph ácido
|
|
WO2020014543A2
(en)
|
2018-07-11 |
2020-01-16 |
Actym Therapeutics, Inc. |
Engineered immunostimulatory bacterial strains and uses thereof
|
|
BR112021000727A2
(pt)
|
2018-07-20 |
2021-04-13 |
Surface Oncology, Inc. |
Composições anti-cd112r e métodos
|
|
ES2974964T3
(es)
|
2018-08-16 |
2024-07-02 |
Innate Tumor Immunity Inc |
Moduladores de NLRP3 derivados de imidazo[4,5-c]quinolina
|
|
JP7364663B2
(ja)
|
2018-08-16 |
2023-10-18 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
イミダゾ［４，５－ｃ］キノリン誘導体のＮＬＲＰ３モジュレーター
|
|
JP2021534180A
(ja)
|
2018-08-16 |
2021-12-09 |
イネイト・テューマー・イミュニティ・インコーポレイテッドInnate Tumor Immunity, Inc. |
置換４−アミノ−１Ｈ−イミダゾ［４，５−ｃ］キノリン化合物およびその製造の改良法
|
|
EP3617230A1
(de)
|
2018-09-03 |
2020-03-04 |
BioInvent International AB |
Neuartige antikörper und nukleotidsequenzen und verwendungen davon
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
WO2020058372A1
(en)
|
2018-09-19 |
2020-03-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of cancers resistant to immune checkpoint therapy
|
|
EP3854805A4
(de)
|
2018-09-21 |
2022-08-24 |
Innovent Biologics (Suzhou) Co., Ltd. |
Neuartiges interleukin 2 und seine verwendung
|
|
TWI791894B
(zh)
|
2018-09-21 |
2023-02-11 |
大陸商信達生物製藥（蘇州）有限公司 |
新型白介素２及其用途
|
|
WO2020070053A1
(en)
|
2018-10-01 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
AU2019355971B2
(en)
|
2018-10-03 |
2025-05-08 |
Xencor, Inc. |
IL-12 heterodimeric Fc-fusion proteins
|
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
|
CN113423734A
(zh)
|
2018-10-12 |
2021-09-21 |
Xencor股份有限公司 |
靶向PD-1的IL-15/IL-15RαFC融合蛋白及其在联合疗法中的应用
|
|
KR20210081384A
(ko)
|
2018-10-23 |
2021-07-01 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
MX2021004906A
(es)
|
2018-10-29 |
2021-09-10 |
Mersana Therapeutics Inc |
Conjugados de anticuerpo modificado con cisteína-fármaco con enlazadores que contienen péptidos.
|
|
CN113330310A
(zh)
|
2018-11-09 |
2021-08-31 |
皮埃里亚生物科学有限责任公司 |
用于测定肿瘤微环境组成的方法和组合物
|
|
KR20210092769A
(ko)
|
2018-11-16 |
2021-07-26 |
브리스톨-마이어스 스큅 컴퍼니 |
항-nkg2a 항체 및 그의 용도
|
|
US20220033848A1
(en)
|
2018-11-19 |
2022-02-03 |
Board Of Regents, The University Of Texas System |
A modular, polycistronic vector for car and tcr transduction
|
|
KR20210096638A
(ko)
|
2018-11-28 |
2021-08-05 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
억제성 환경에 대한 기능 및 내성을 증진시키기 위한 면역 세포의 멀티플렉스 게놈 편집
|
|
US20220018828A1
(en)
|
2018-11-28 |
2022-01-20 |
Inserm (Institut National De La Santé Et La Recherche Médicale |
Methods and kit for assaying lytic potential of immune effector cells
|
|
WO2020112781A1
(en)
|
2018-11-28 |
2020-06-04 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
CA3121210A1
(en)
|
2018-11-29 |
2020-06-04 |
Board Of Regents, The University Of Texas System |
Methods for ex vivo expansion of natural killer cells and use thereof
|
|
US20220018835A1
(en)
|
2018-12-07 |
2022-01-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
SG11202104331YA
(en)
|
2018-12-11 |
2021-05-28 |
Theravance Biopharma R&D Ip Llc |
Naphthyridine and quinoline derivatives useful as alk5 inhibitors
|
|
US20220047556A1
(en)
|
2018-12-17 |
2022-02-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sulconazole as a furin inhibitor
|
|
WO2020139926A2
(en)
|
2018-12-26 |
2020-07-02 |
Akrevia Therapeutics Inc. |
Anti-ctla4 antibodies and methods of use thereof
|
|
JP7625521B2
(ja)
|
2018-12-28 |
2025-02-03 |
トランスジーン |
ｍ２欠陥ポックスウイルス
|
|
WO2020150116A1
(en)
|
2019-01-14 |
2020-07-23 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
KR102815870B1
(ko)
|
2019-01-14 |
2025-05-30 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
암의 치료에 사용하기 위한 헤테로시클릭 nlrp3 조정제
|
|
US12187706B2
(en)
|
2019-01-14 |
2025-01-07 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
|
EP3911641A1
(de)
|
2019-01-14 |
2021-11-24 |
Innate Tumor Immunity, Inc. |
Nlrp3-modulatoren
|
|
BR112021013944A8
(pt)
|
2019-01-15 |
2023-02-07 |
Univ Nantes |
Polipeptídeos de interleucina-34 (il-34) mutada e usos dos mesmos em terapias
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
EP3938048A1
(de)
|
2019-03-13 |
2022-01-19 |
eTheRNA Immunotherapies NV |
Mrna-impfstoff
|
|
EP3942024A4
(de)
|
2019-03-18 |
2023-03-22 |
The Regents of the University of California |
Erhöhung der t-zell-aktivierung durch oszillierende kräfte und gentechnisch hergestellte antigen-präsentierende zellen
|
|
WO2020198672A1
(en)
|
2019-03-28 |
2020-10-01 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
WO2020198676A1
(en)
|
2019-03-28 |
2020-10-01 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3947737A2
(de)
|
2019-04-02 |
2022-02-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren zur vorhersage und vorbeugung von krebs bei patienten mit prämalignen läsionen
|
|
WO2020206169A1
(en)
|
2019-04-02 |
2020-10-08 |
Kupper Thomas S |
Methods for identifying progression of a primary melanoma
|
|
EP3952850A1
(de)
|
2019-04-09 |
2022-02-16 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Verwendung von sk2-inhibitoren in kombination mit einer immun-checkpoint-blockadetherapie zur behandlung von krebs
|
|
EP3956446A1
(de)
|
2019-04-17 |
2022-02-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren und zusammensetzungen zur behandlung von durch nlrp3-inflammasom vermittelten il-1-beta-abhängigen erkrankungen
|
|
EP3966315A1
(de)
|
2019-05-09 |
2022-03-16 |
FUJIFILM Cellular Dynamics, Inc. |
Verfahren zur herstellung von hepatozyten
|
|
US10945981B2
(en)
|
2019-05-17 |
2021-03-16 |
Cancer Prevention Pharmaceuticals, Inc. |
Methods for treating familial adenomatous polyposis
|
|
KR20220016156A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
면역-종양학 요법에의 적합성을 위한 다종양 유전자 시그너쳐
|
|
WO2020243570A1
(en)
|
2019-05-30 |
2020-12-03 |
Bristol-Myers Squibb Company |
Cell localization signature and combination therapy
|
|
CN114127315A
(zh)
|
2019-05-30 |
2022-03-01 |
百时美施贵宝公司 |
鉴定适合于免疫肿瘤学(i-o)疗法的受试者的方法
|
|
EP3976111A4
(de)
|
2019-06-03 |
2023-07-05 |
The University of Chicago |
Verfahren und zusammensetzungen zur behandlung von krebs mit kollagenbindenden arzneimittelträgern
|
|
EP3976061A4
(de)
|
2019-06-03 |
2023-07-12 |
The University of Chicago |
Verfahren und zusammensetzungen zur behandlung von krebs mit gegen krebs gerichteten adjuvanzien
|
|
US20210038684A1
(en)
|
2019-06-11 |
2021-02-11 |
Alkermes Pharma Ireland Limited |
Compositions and Methods for Cancer Immunotherapy
|
|
KR20220061946A
(ko)
|
2019-06-27 |
2022-05-13 |
이더알엔에이 이뮤노테라피스 엔브이 |
병용 요법
|
|
WO2021003432A1
(en)
|
2019-07-02 |
2021-01-07 |
Fred Hutchinson Cancer Research Center |
Recombinant ad35 vectors and related gene therapy improvements
|
|
EP3999539A1
(de)
|
2019-07-15 |
2022-05-25 |
Intervet International B.V. |
Caninisierte antikörper gegen humanes und canines ctla-4
|
|
US12435143B2
(en)
|
2019-07-15 |
2025-10-07 |
Intervet Inc. |
Caninized antibodies against canine CTLA-4
|
|
WO2021024742A1
(ja)
*
|
2019-08-06 |
2021-02-11 |
国立大学法人筑波大学 |
細胞傷害アッセイ方法
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
AU2020349519A1
(en)
|
2019-09-17 |
2022-03-17 |
Bial-R&D Investments, S.A. |
Substituted N-heterocyclic carboxamides as acid ceramidase inhibitors and their use as medicaments
|
|
KR20220100858A
(ko)
|
2019-09-17 |
2022-07-18 |
비알 - 알&디 인베스트먼츠, 에스.에이. |
치환된 이미다졸 카르복사미드, 및 질병의 치료에서의 이의 용도
|
|
CA3150906A1
(en)
|
2019-09-17 |
2021-03-25 |
Renato T. Skerlj |
Substituted, saturated and unsaturated n-heterocyclic carboxamides and related compounds for their use in the treatment of medical disorders
|
|
EP4031575A1
(de)
|
2019-09-19 |
2022-07-27 |
Bristol-Myers Squibb Company |
An vista bei saurem ph-wert bindende antikörper
|
|
US20220348653A1
(en)
|
2019-09-22 |
2022-11-03 |
Bristol-Myers Squibb Company |
Quantitative Spatial Profiling for LAG-3 Antagonist Therapy
|
|
EP4034253A4
(de)
|
2019-09-23 |
2024-02-07 |
The Regents Of The University Of Michigan |
Zusammensetzungen und verfahren zur erhöhung der wirksamkeit von immuntherapien und impfstoffen
|
|
WO2021062244A1
(en)
|
2019-09-25 |
2021-04-01 |
Surface Oncology, Inc. |
Anti-il-27 antibodies and uses thereof
|
|
EP3800201A1
(de)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h-stimulierung verbessert nk-zellen-abtötungsaktivitäten
|
|
US11851466B2
(en)
|
2019-10-03 |
2023-12-26 |
Xencor, Inc. |
Targeted IL-12 heterodimeric Fc-fusion proteins
|
|
WO2021064184A1
(en)
|
2019-10-04 |
2021-04-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
KR20220088425A
(ko)
|
2019-10-25 |
2022-06-27 |
다이이찌 산쿄 가부시키가이샤 |
항 garp 항체와 면역 조절제의 조합
|
|
WO2021087458A2
(en)
|
2019-11-02 |
2021-05-06 |
Board Of Regents, The University Of Texas System |
Targeting nonsense-mediated decay to activate p53 pathway for the treatment of cancer
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
BR112022008191A2
(pt)
|
2019-11-08 |
2022-07-12 |
Bristol Myers Squibb Co |
Terapia com antagonista de lag-3 para melanoma
|
|
IL293084A
(en)
|
2019-11-22 |
2022-07-01 |
Theravance Biopharma R& D Ip Llc |
Substituted 1,5-naphthyridines or quinolines as alk5 inhibitors
|
|
TW202128155A
(zh)
|
2019-11-27 |
2021-08-01 |
日商賽多利克公司 |
醫藥組成物
|
|
WO2021113644A1
(en)
|
2019-12-05 |
2021-06-10 |
Multivir Inc. |
Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer
|
|
EP4076529A1
(de)
|
2019-12-19 |
2022-10-26 |
Bristol-Myers Squibb Company |
Kombinationen von dgk-inhibitoren und checkpoint-antagonisten
|
|
MX2022007840A
(es)
|
2019-12-27 |
2022-07-19 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti antigeno-4 asociado al linfocito t citotoxico (ctla4) y uso del mismo.
|
|
WO2021141977A1
(en)
|
2020-01-07 |
2021-07-15 |
Board Of Regents, The University Of Texas System |
Improved human methyl thioadenosine/adenosine depleting enzyme variants for cancer therapy
|
|
CN115244052A
(zh)
|
2020-01-10 |
2022-10-25 |
先天肿瘤免疫公司 |
Nlrp3调节剂
|
|
WO2021159024A1
(en)
|
2020-02-05 |
2021-08-12 |
Larimar Therapeutics, Inc. |
Tat peptide binding proteins and uses thereof
|
|
JP2023514152A
(ja)
|
2020-02-06 |
2023-04-05 |
ブリストル－マイヤーズ スクイブ カンパニー |
Ｉｌ－１０およびその使用
|
|
CA3168337A1
(en)
|
2020-02-17 |
2021-08-26 |
Marie-Andree Forget |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
|
WO2021170750A1
(en)
|
2020-02-28 |
2021-09-02 |
Orega Biotech |
Combination therapies based on ctla4 and il-17b inhibitors
|
|
EP4114449A2
(de)
|
2020-03-05 |
2023-01-11 |
Neotx Therapeutics Ltd. |
Verfahren und zusammensetzungen zur behandlung von krebs mit immunzellen
|
|
US20230140384A1
(en)
|
2020-03-09 |
2023-05-04 |
Bristol-Myers Squibb Company |
Antibodies to cd40 with enhanced agonist activity
|
|
JP2023519346A
(ja)
|
2020-03-27 |
2023-05-10 |
メンドゥス・ベスローテン・フェンノートシャップ |
養子細胞療法の有効性を増強するための白血病由来の改変細胞のエクスビボ（ｅｘ ｖｉｖｏ）使用
|
|
JP2023519673A
(ja)
|
2020-03-31 |
2023-05-12 |
セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー |
置換ピリミジンおよび使用方法
|
|
US20230272056A1
(en)
|
2020-04-09 |
2023-08-31 |
Merck Sharp & Dohme Llc |
Affinity matured anti-lap antibodies and uses thereof
|
|
WO2021211331A1
(en)
|
2020-04-13 |
2021-10-21 |
Abbott Point Of Care Inc. |
METHODS, COMPLEXES AND KITS FOR DETECTING OR DETERMINING AN AMOUNT OF A ß-CORONAVIRUS ANTIBODY IN A SAMPLE
|
|
EP4139289A1
(de)
|
2020-04-21 |
2023-03-01 |
University of Rochester |
Inhibitoren des humanen epididymusproteins 4
|
|
US12159700B2
(en)
|
2020-04-22 |
2024-12-03 |
Iovance Biotherapeutics, Inc. |
Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy
|
|
IL297437A
(en)
|
2020-05-13 |
2022-12-01 |
Disc Medicine Inc |
Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
|
|
EP4149547A4
(de)
|
2020-05-13 |
2024-08-14 |
Adagene AG |
Zusammensetzungen und verfahren zur behandlung von krebs
|
|
WO2021231732A1
(en)
|
2020-05-15 |
2021-11-18 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
JP2023526416A
(ja)
|
2020-05-21 |
2023-06-21 |
ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム |
Ｖｇｌｌ１特異性を有するｔ細胞受容体およびその使用法
|
|
CN115803062B
(zh)
|
2020-06-03 |
2025-09-09 |
博泰康医药公司 |
滋养层细胞表面抗原2(trop-2)抗体
|
|
WO2021247836A1
(en)
|
2020-06-03 |
2021-12-09 |
Board Of Regents, The University Of Texas System |
Methods for targeting shp-2 to overcome resistance
|
|
WO2021245071A1
(en)
|
2020-06-03 |
2021-12-09 |
Mv Biotherapeutics Sa |
Combination of an atp-hydrolyzing enzyme and an immune checkpoint modulator and uses thereof
|
|
US20210387983A1
(en)
|
2020-06-10 |
2021-12-16 |
Theravance Biopharma R&D Ip, Llc |
Crystalline alk5 inhibitors and uses thereof
|
|
US20230293530A1
(en)
|
2020-06-24 |
2023-09-21 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
|
CN116133679A
(zh)
|
2020-06-30 |
2023-05-16 |
门德斯有限公司 |
白血病衍生细胞在卵巢癌疫苗中的用途
|
|
WO2022003156A1
(en)
|
2020-07-02 |
2022-01-06 |
Oncurious Nv |
Ccr8 non-blocking binders
|
|
CA3182579A1
(en)
|
2020-07-07 |
2022-01-13 |
Ugur Sahin |
Therapeutic rna for hpv-positive cancer
|
|
WO2022010847A1
(en)
|
2020-07-07 |
2022-01-13 |
Cancure, Llc |
Mic antibodies and binding agents and methods of using the same
|
|
US20230295146A1
(en)
|
2020-07-24 |
2023-09-21 |
The University Of Rochester |
Inhibitors of interleukin-1 receptor-associated kinases 1 and 4
|
|
CA3189336A1
(en)
|
2020-07-24 |
2022-01-27 |
Amgen Inc. |
Immunogens derived from sars-cov2 spike protein
|
|
WO2022031804A1
(en)
|
2020-08-04 |
2022-02-10 |
Abbott Laboratories |
Improved methods and kits for detecting sars-cov-2 protein in a sample
|
|
CN112359052B
(zh)
*
|
2020-08-20 |
2023-01-03 |
山东兴瑞生物科技有限公司 |
抗EpCAM嵌合抗原受体的编码基因、制备方法、具有该基因的质粒、免疫细胞及其应用
|
|
AU2021331476A1
(en)
|
2020-08-28 |
2023-05-04 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hepatocellular carcinoma
|
|
KR20230061430A
(ko)
|
2020-08-31 |
2023-05-08 |
브리스톨-마이어스 스큅 컴퍼니 |
세포 국재화 시그너쳐 및 면역요법
|
|
IL301907A
(en)
|
2020-10-23 |
2023-06-01 |
Bristol Myers Squibb Co |
Lag-3 antagonist therapy for lung cancer
|
|
WO2022098845A1
(en)
|
2020-11-05 |
2022-05-12 |
Board Of Regents, The University Of Texas System |
Engineered t cell receptors targeting egfr antigens and methods of use
|
|
IL302728A
(en)
|
2020-11-13 |
2023-07-01 |
Catamaran Bio Inc |
Genetically modified natural killer cells and methods of use thereof
|
|
WO2022115611A1
(en)
|
2020-11-25 |
2022-06-02 |
Catamaran Bio, Inc. |
Cellular therapeutics engineered with signal modulators and methods of use thereof
|
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
US20220170948A1
(en)
|
2020-12-01 |
2022-06-02 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a human subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
PH12023500013A1
(en)
|
2020-12-04 |
2024-03-11 |
Tidal Therapeutics Inc |
Ionizable cationic lipids and lipi nanoparticles, and methods of synthesis and use thereof
|
|
JP2024500093A
(ja)
*
|
2020-12-10 |
2024-01-04 |
ウーシー バイオロジクス アイルランド リミテッド |
Ｐ－カドヘリンに対する抗体及びその使用
|
|
WO2022130206A1
(en)
|
2020-12-16 |
2022-06-23 |
Pfizer Inc. |
TGFβr1 INHIBITOR COMBINATION THERAPIES
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性ｒｎａ
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
WO2022136647A1
(en)
|
2020-12-24 |
2022-06-30 |
Oncurious Nv |
Human ccr8 binders
|
|
US20240052045A1
(en)
|
2020-12-24 |
2024-02-15 |
Vib Vzw |
Murine cross-reactive human ccr8 binders
|
|
EP4267618A1
(de)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Nichtblockierende, menschliche ccr8-bindemittel
|
|
CA3196999A1
(en)
|
2020-12-28 |
2022-07-07 |
Masano HUANG |
Methods of treating tumors
|
|
SI4267105T1
(sl)
|
2020-12-28 |
2025-07-31 |
Bristol-Myers Squibb Company |
Sestave protiteles in načini njihove uporabe
|
|
WO2022147147A1
(en)
|
2020-12-30 |
2022-07-07 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
|
CA3205538A1
(en)
|
2021-01-19 |
2022-07-28 |
Han XIAO |
Bone-specific delivery of polypeptides
|
|
KR20230135075A
(ko)
|
2021-01-22 |
2023-09-22 |
멘두스 비.브이. |
종양 백신접종 방법
|
|
JP2024506839A
(ja)
|
2021-01-29 |
2024-02-15 |
ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム |
キナーゼ阻害剤を用いてがんを処置する方法
|
|
KR20230157388A
(ko)
|
2021-03-12 |
2023-11-16 |
멘두스 비.브이. |
백신접종의 방법 및 cd47 차단의 용도
|
|
JP2024514530A
(ja)
|
2021-04-02 |
2024-04-02 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
切断型ｃｄｃｐ１に対する抗体およびその使用
|
|
EP4070799A1
(de)
|
2021-04-08 |
2022-10-12 |
Nuvamid SA |
Zusammensetzungen zur verbesserung der sportlichen leistung
|
|
US20240279225A1
(en)
|
2021-04-08 |
2024-08-22 |
Board Of Regents, The University Of Texas System |
Compounds and methods for theranostic targeting of parp activity
|
|
TW202304524A
(zh)
|
2021-04-10 |
2023-02-01 |
美商普方生物製藥美國公司 |
Folr1結合劑、其結合物及使用方法
|
|
EP4079310A1
(de)
|
2021-04-20 |
2022-10-26 |
Nuvamid SA |
Nmn und derivate zur verwendung in der behandlung von alpha-synucleinopathien
|
|
EP4079311B1
(de)
|
2021-04-20 |
2025-10-01 |
Nuvamid SA |
Nmn und derivate zur verwendung bei der behandlung von depression und/oder angst bei patienten mit einer form von parkinsonismus
|
|
EP4326321A1
(de)
|
2021-04-20 |
2024-02-28 |
Institut Curie |
Zusammensetzungen und verfahren zur verwendung in der immuntherapie
|
|
AU2022262644A1
(en)
|
2021-04-23 |
2023-11-09 |
Genmab A/S |
Anti-cd70 antibodies, conjugates thereof and methods of using the same
|
|
JP2024519858A
(ja)
|
2021-05-18 |
2024-05-21 |
アボット・ラボラトリーズ |
小児対象における脳損傷を査定する方法
|
|
WO2022251359A1
(en)
|
2021-05-26 |
2022-12-01 |
Theravance Biopharma R&D Ip, Llc |
Bicyclic inhibitors of alk5 and methods of use
|
|
EP4351595A1
(de)
|
2021-06-07 |
2024-04-17 |
Providence Health & Services - Oregon |
Cxcr5, pd-1 und icos mit expression tumorreaktiver cd4-t-zellen und deren verwendung
|
|
EP4528280A3
(de)
|
2021-06-14 |
2025-07-02 |
Abbott Laboratories |
Verfahren zur diagnose oder unterstützung der diagnose von hirnverletzungen durch akustische energie, elektromagnetische energie, überdruckwelle und/oder explosionswind
|
|
US12448451B2
(en)
|
2021-06-25 |
2025-10-21 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-CTLA-4 antibody and use thereof
|
|
WO2022270611A1
(ja)
|
2021-06-25 |
2022-12-29 |
中外製薬株式会社 |
抗ｃｔｌａ－４抗体
|
|
WO2022270612A1
(ja)
|
2021-06-25 |
2022-12-29 |
中外製薬株式会社 |
抗ｃｔｌａ－４抗体の使用
|
|
US20240316005A1
(en)
|
2021-07-05 |
2024-09-26 |
Institut National de la Santé et de la Recherche Médicale |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
MX2024000674A
(es)
|
2021-07-13 |
2024-02-07 |
BioNTech SE |
Agentes de union multiespecificos contra cd40 y cd137 en terapia de combinacion.
|
|
CA3228262A1
(en)
|
2021-08-04 |
2023-02-09 |
The Regents Of The University Of Colorado, A Body Corporate |
Lat activating chimeric antigen receptor t cells and methods of use thereof
|
|
KR20240099138A
(ko)
|
2021-08-23 |
2024-06-28 |
이뮤니타스 테라퓨틱스, 인크. |
항-cd161 항체 및 그의 용도
|
|
CN118715440A
(zh)
|
2021-08-31 |
2024-09-27 |
雅培实验室 |
诊断脑损伤的方法和系统
|
|
EP4396587A1
(de)
|
2021-08-31 |
2024-07-10 |
Abbott Laboratories |
Verfahren und systeme zur diagnose von hirnverletzungen
|
|
JP2024538608A
(ja)
|
2021-09-30 |
2024-10-23 |
アボット・ラボラトリーズ |
脳の損傷を診断する方法及びシステム
|
|
EP4413117A1
(de)
|
2021-10-05 |
2024-08-14 |
Cytovia Therapeutics, Llc. |
Natürliche killerzellen und verfahren zur verwendung davon
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
AR127408A1
(es)
|
2021-10-20 |
2024-01-17 |
Takeda Pharmaceuticals Co |
Composiciones dirigidas a bcma y métodos de uso de las mismas
|
|
WO2023076880A1
(en)
|
2021-10-25 |
2023-05-04 |
Board Of Regents, The University Of Texas System |
Foxo1-targeted therapy for the treatment of cancer
|
|
CN118176214A
(zh)
|
2021-10-29 |
2024-06-11 |
百时美施贵宝公司 |
血液癌症的lag-3拮抗剂疗法
|
|
JP2024540536A
(ja)
|
2021-11-19 |
2024-10-31 |
アーディアジェン コーポレーション |
Ｇｐｃ３結合剤、そのコンジュゲートおよびその使用方法
|
|
CN119278213A
(zh)
*
|
2021-11-24 |
2025-01-07 |
丹娜-法伯癌症研究院 |
针对ctla-4的抗体及其使用方法
|
|
CA3240822A1
(en)
|
2021-12-17 |
2023-06-22 |
Tony Lee |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
|
TW202332687A
(zh)
|
2021-12-23 |
2023-08-16 |
比利時商ｅＴｈｅＲＮＡ免疫治療公司 |
免疫刺激性mrna組成物及其用途
|
|
KR20240135661A
(ko)
|
2022-01-26 |
2024-09-11 |
브리스톨-마이어스 스큅 컴퍼니 |
간세포성 암종에 대한 조합 요법
|
|
CN119256227A
(zh)
|
2022-02-04 |
2025-01-03 |
雅培实验室 |
用于检测样品中泛素羧基末端水解酶l1和/或胶质纤维酸性蛋白的存在或测量其量的侧向流方法、测定和装置
|
|
CA3251366A1
(en)
|
2022-02-25 |
2023-08-31 |
Bristol Myers Squibb Co |
POLYTHERAPY AGAINST COLORECTAL CARCINOMA
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
CN119156403A
(zh)
|
2022-03-08 |
2024-12-17 |
阿伦蒂斯治疗股份公司 |
抗紧密连接蛋白-1抗体增加t细胞可用性的用途
|
|
EP4493195A1
(de)
|
2022-03-15 |
2025-01-22 |
Compugen Ltd. |
Il-18bp-antagonist-antikörper und deren verwendung in der monotherapie und kombinationstherapie bei der behandlung von krebs
|
|
KR20240161968A
(ko)
|
2022-03-16 |
2024-11-13 |
다이이찌 산쿄 가부시키가이샤 |
다중 특이적 분자와 면역 체크 포인트 저해제의 조합
|
|
US20250206775A1
(en)
|
2022-03-18 |
2025-06-26 |
Bristol-Myers Squibb Company |
Methods of isolating polypeptides
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP4507704A1
(de)
|
2022-04-15 |
2025-02-19 |
Iovance Biotherapeutics, Inc. |
Til-expansionsverfahren unter verwendung spezifischer zytokinkombinationen und/oder einer akti-behandlung
|
|
US20250235478A1
(en)
|
2022-04-28 |
2025-07-24 |
Musc Foundation For Research Development |
Chimeric antigen receptor modified regulatory t cells for treating cancer
|
|
WO2023213763A1
(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
|
|
WO2023213764A1
(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
|
|
CN119255825A
(zh)
|
2022-05-24 |
2025-01-03 |
第一三共株式会社 |
抗-cdh6抗体-药物缀合物的剂量方案
|
|
CA3258064A1
(en)
|
2022-06-02 |
2023-12-07 |
Bristol Myers Squibb Co |
ANTIBODY COMPOSITIONS AND THEIR METHODS OF USE
|
|
TW202423482A
(zh)
|
2022-06-08 |
2024-06-16 |
美商泰德治療公司 |
可電離陽離子脂質和脂質奈米顆粒、及其合成方法和用途
|
|
GB202209518D0
(en)
|
2022-06-29 |
2022-08-10 |
Snipr Biome Aps |
Treating & preventing E coli infections
|
|
CN120167040A
(zh)
|
2022-06-29 |
2025-06-17 |
雅培实验室 |
用于确定生物样本中的gfap的磁性定点照护型系统和测定
|
|
KR20250034101A
(ko)
|
2022-07-01 |
2025-03-10 |
트랜스진 |
계면활성제-단백질-d 및 tnfsf의 구성원을 포함하는 융합 단백질
|
|
CA3262449A1
(en)
|
2022-07-28 |
2024-02-01 |
Astrazeneca Uk Ltd |
COMBINATION OF AN ANTIBODY-DRUG CONJUGATE AND A BISPECIFIC CHECKPOINT INHIBITOR
|
|
WO2024028794A1
(en)
|
2022-08-02 |
2024-02-08 |
Temple Therapeutics BV |
Methods for treating endometrial and ovarian hyperproliferative disorders
|
|
EP4583860A1
(de)
|
2022-09-06 |
2025-07-16 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitoren des ceramid-stoffwechselwegs zur überwindung der immuntherapieresistenz bei krebs
|
|
AU2023342055A1
(en)
|
2022-09-15 |
2025-03-13 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|
|
WO2024086827A2
(en)
|
2022-10-20 |
2024-04-25 |
Repertoire Immune Medicines, Inc. |
Cd8 t cell targeted il2
|
|
KR20250122544A
(ko)
|
2022-11-21 |
2025-08-13 |
이오반스 바이오테라퓨틱스, 인크. |
종양 침윤 림프구의 확장을 위한 2차원 공정 및 이를 통한 요법
|
|
IL321098A
(en)
|
2022-12-14 |
2025-07-01 |
Astellas Pharma Europe Bv |
Combination therapy including bispecific binding agents that bind to CLDN18.2- and CD3- and immune checkpoint inhibitors
|
|
CN120731228A
(zh)
|
2022-12-21 |
2025-09-30 |
百时美施贵宝公司 |
肺癌的组合疗法
|
|
EP4658687A1
(de)
|
2023-01-31 |
2025-12-10 |
University of Rochester |
Immuncheckpoint-blockadetherapie zur behandlung von staphylococcus-aureus-infektionen
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024211475A1
(en)
|
2023-04-04 |
2024-10-10 |
Abbott Laboratories |
Use of biomarkers to determine whether a subject has sustained, may have sustained or is suspected of sustaining a subacute acquired brain injury (abi)
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
WO2024226969A1
(en)
|
2023-04-28 |
2024-10-31 |
Abbott Point Of Care Inc. |
Improved assays, cartridges, and kits for detection of biomarkers, including brain injury biomarkers
|
|
WO2024261302A1
(en)
|
2023-06-22 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Nlrp3 inhibitors, pak1/2 inhibitors and/or caspase 1 inhibitors for use in the treatment of rac2 monogenic disorders
|
|
TW202515608A
(zh)
|
2023-06-26 |
2025-04-16 |
以色列商坎布根有限公司 |
Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途
|
|
WO2025003193A1
(en)
|
2023-06-26 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Sertraline and indatraline for disrupting intracellular cholesterol trafficking and subsequently inducing lysosomal damage and anti-tumor immunity
|
|
EP4484445A1
(de)
|
2023-06-26 |
2025-01-01 |
Universität zu Köln |
Hcmv neutralisierende antikörper
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
WO2025050009A2
(en)
|
2023-09-01 |
2025-03-06 |
Children's Hospital Medical Center |
Identification of targets for immunotherapy in melanoma using splicing-derived neoantigens
|
|
WO2025061994A1
(en)
|
2023-09-21 |
2025-03-27 |
Domain Therapeutics |
Anti-ccr8 monoclonal antibodies and their therapeutic use
|
|
EP4590714A1
(de)
|
2023-09-21 |
2025-07-30 |
Domain Therapeutics |
Monoklonale anti-ccr8-antikörper und deren therapeutische verwendung
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025133175A1
(en)
|
2023-12-21 |
2025-06-26 |
Egle Therapeutics |
Immunocytokine for cancer treatment
|
|
EP4574165A1
(de)
|
2023-12-21 |
2025-06-25 |
Egle Therapeutics |
Immunozytokine zur krebsbehandlung
|
|
US20250215087A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg depleting agent
|
|
WO2025174825A2
(en)
|
2024-02-12 |
2025-08-21 |
Aera Therapeutics, Inc. |
Delivery compositions
|
|
WO2025184211A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
WO2025202222A1
(en)
|
2024-03-25 |
2025-10-02 |
Institut National de la Santé et de la Recherche Médicale |
Therapeutic use of sting and tlrs agonists to induce p16 expression in immune cells
|
|
WO2025210175A1
(en)
|
2024-04-04 |
2025-10-09 |
Centre National De La Recherche Scientifique |
Mutant csf-1r extracellular domain fusion molecules and therapeutic uses thereof
|
|
WO2025217094A1
(en)
|
2024-04-08 |
2025-10-16 |
University Of Rochester |
Interleukin receptor-associated kinase (irak) protac degraders and medical use thereof
|
|
WO2025217096A1
(en)
|
2024-04-08 |
2025-10-16 |
University Of Rochester |
Inhibitors of leucine-rich repeat kinase 2 (lrrk2) and medical uses thereof
|
|
WO2025245489A1
(en)
|
2024-05-24 |
2025-11-27 |
Bristol-Myers Squibb Company |
Treatment of tumors in subjects having fgl-1 positive samples
|