HU226522B1 - Substituted oxazolidinones, process for their preparation and pharmaceutical compositions containing them their use - Google Patents

Info

Publication number

HU226522B1

HU226522B1 HU0203902A HUP0203902A HU226522B1 HU 226522 B1 HU226522 B1 HU 226522B1 HU 0203902 A HU0203902 A HU 0203902A HU P0203902 A HUP0203902 A HU P0203902A HU 226522 B1 HU226522 B1 HU 226522B1

Authority

HU

Hungary

Prior art keywords

chloro

oxo

preparation

methyl

hplc

Prior art date

1999-12-24

Links

• Espacenet
• Global Dossier
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• 238000000034 method Methods 0.000 title claims description 199
• 238000002360 preparation method Methods 0.000 title claims description 178
• 230000008569 process Effects 0.000 title claims description 18
• 239000008194 pharmaceutical composition Substances 0.000 title claims description 10
• IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title claims description 9
• 150000001875 compounds Chemical class 0.000 claims description 136
• -1 chloro, bromo, methyl Chemical group 0.000 claims description 78
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• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 24
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• 239000003814 drug Substances 0.000 claims description 15
• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 13
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• 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims description 6
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• QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 4
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• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 28
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• HQZBFUCRRYMCAS-UHFFFAOYSA-N 5-(aminomethyl)-3-[4-(2-oxopyrrolidin-1-yl)phenyl]-1,3-oxazolidin-2-one Chemical compound O=C1OC(CN)CN1C1=CC=C(N2C(CCC2)=O)C=C1 HQZBFUCRRYMCAS-UHFFFAOYSA-N 0.000 description 8
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