FR18C1031I2 - Molecule de liaison a un antigene multi-specifique ayant une fonction alternative par rapport a la fonction du facteur viii de coagulation sanguine - Google Patents
Molecule de liaison a un antigene multi-specifique ayant une fonction alternative par rapport a la fonction du facteur viii de coagulation sanguineInfo
- Publication number
- FR18C1031I2 FR18C1031I2 FR18C1031C FR18C1031C FR18C1031I2 FR 18C1031 I2 FR18C1031 I2 FR 18C1031I2 FR 18C1031 C FR18C1031 C FR 18C1031C FR 18C1031 C FR18C1031 C FR 18C1031C FR 18C1031 I2 FR18C1031 I2 FR 18C1031I2
- Authority
- FR
- France
- Prior art keywords
- function
- binding molecule
- factor viii
- specific antigen
- blood coagulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2010257022 | 2010-11-17 | ||
PCT/JP2011/076486 WO2012067176A1 (ja) | 2010-11-17 | 2011-11-17 | 血液凝固第viii因子の機能を代替する機能を有する多重特異性抗原結合分子 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR18C1031I1 FR18C1031I1 (ja) | 2018-08-31 |
FR18C1031I2 true FR18C1031I2 (fr) | 2020-09-25 |
Family
ID=46084097
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR18C1031C Active FR18C1031I2 (fr) | 2010-11-17 | 2018-07-19 | Molecule de liaison a un antigene multi-specifique ayant une fonction alternative par rapport a la fonction du facteur viii de coagulation sanguine |
Country Status (29)
Country | Link |
---|---|
US (9) | US9334331B2 (ja) |
EP (2) | EP2644698B1 (ja) |
JP (7) | JP6013915B2 (ja) |
KR (4) | KR102099580B1 (ja) |
CN (2) | CN105859889B (ja) |
AU (2) | AU2011330184B2 (ja) |
BR (1) | BR112013012213A2 (ja) |
CA (1) | CA2817964C (ja) |
DK (1) | DK2644698T3 (ja) |
ES (1) | ES2660151T3 (ja) |
FR (1) | FR18C1031I2 (ja) |
HK (1) | HK1223379A1 (ja) |
HR (1) | HRP20180421T1 (ja) |
HU (2) | HUE038305T2 (ja) |
LT (2) | LT2644698T (ja) |
LU (1) | LUC00076I2 (ja) |
MX (1) | MX355060B (ja) |
MY (1) | MY166429A (ja) |
NL (1) | NL300940I2 (ja) |
NO (2) | NO2644698T3 (ja) |
PH (1) | PH12016502073A1 (ja) |
PL (1) | PL2644698T3 (ja) |
PT (1) | PT2644698T (ja) |
RS (1) | RS57038B1 (ja) |
RU (3) | RU2620071C2 (ja) |
SI (1) | SI2644698T1 (ja) |
TR (1) | TR201802772T4 (ja) |
TW (4) | TWI629355B (ja) |
WO (1) | WO2012067176A1 (ja) |
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US11046784B2 (en) | 2006-03-31 | 2021-06-29 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
LT3345607T (lt) | 2006-12-29 | 2023-01-10 | Ossifi-Mab Llc | Kaulų augimo keitimo būdai, skiriant sost arba wise antagonistą ar agonistą |
PT2716301T (pt) * | 2007-02-16 | 2017-07-04 | Merrimack Pharmaceuticals Inc | Anticorpos contra erbb3 e suas utilizações |
SI2202245T1 (sl) | 2007-09-26 | 2016-10-28 | Chugai Seiyaku Kabushiki Kaisha | Postopek modificiranja izoelektrične točke protitelesa preko aminokislinske substitucije v CDR |
MY163473A (en) | 2007-09-26 | 2017-09-15 | Chugai Pharmaceutical Co Ltd | Modified antibody constant region |
JP5787446B2 (ja) | 2009-03-19 | 2015-09-30 | 中外製薬株式会社 | 抗体定常領域改変体 |
WO2010107110A1 (ja) | 2009-03-19 | 2010-09-23 | 中外製薬株式会社 | 抗体定常領域改変体 |
US20130018174A1 (en) * | 2009-12-25 | 2013-01-17 | Chugai Seiyaku Kabushiki Kaisha | Polypeptide modification method for purifying polypeptide multimers |
AR080428A1 (es) | 2010-01-20 | 2012-04-11 | Chugai Pharmaceutical Co Ltd | Formulaciones liquidas estabilizadas contentivas de anticuerpos |
EP2543730B1 (en) | 2010-03-04 | 2018-10-31 | Chugai Seiyaku Kabushiki Kaisha | Antibody constant region variant |
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MX2019001355A (es) | 2012-05-10 | 2023-01-17 | Bioatla Llc | Anticuerpos monoclonales multiespecíficos. |
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2016
- 2016-04-19 US US15/132,996 patent/US10450381B2/en active Active
- 2016-05-30 AU AU2016203564A patent/AU2016203564B2/en active Active
- 2016-09-23 JP JP2016185421A patent/JP6710131B2/ja active Active
- 2016-10-05 HK HK16111570.7A patent/HK1223379A1/zh unknown
- 2016-10-07 US US15/288,965 patent/US20170022293A1/en not_active Abandoned
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2018
- 2018-03-09 HR HRP20180421TT patent/HRP20180421T1/hr unknown
- 2018-05-30 LU LU00076C patent/LUC00076I2/en unknown
- 2018-05-30 NL NL300940C patent/NL300940I2/nl unknown
- 2018-06-13 LT LTPA2018507C patent/LTC2644698I2/lt unknown
- 2018-06-21 HU HUS1800029C patent/HUS1800029I1/hu unknown
- 2018-07-19 FR FR18C1031C patent/FR18C1031I2/fr active Active
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2019
- 2019-03-05 JP JP2019039114A patent/JP6823677B2/ja active Active
- 2019-07-02 US US16/459,791 patent/US20190315884A1/en not_active Abandoned
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2021
- 2021-01-08 JP JP2021002057A patent/JP2021065233A/ja active Pending
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2022
- 2022-04-26 US US17/729,471 patent/US20220267470A1/en not_active Abandoned
- 2022-10-12 JP JP2022163711A patent/JP2022191374A/ja active Pending
- 2022-12-15 US US18/081,874 patent/US20230212315A1/en not_active Abandoned
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2023
- 2023-09-06 NO NO2023034C patent/NO2023034I1/no unknown
- 2023-10-27 US US18/495,861 patent/US20240059795A1/en active Pending
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