DE3583750D1 - Hybridom-zellinien und monoklonale antikoerper gegen faktor-viii-c. - Google Patents

Hybridom-zellinien und monoklonale antikoerper gegen faktor-viii-c.

Info

Publication number
DE3583750D1
DE3583750D1 DE8585100224T DE3583750T DE3583750D1 DE 3583750 D1 DE3583750 D1 DE 3583750D1 DE 8585100224 T DE8585100224 T DE 8585100224T DE 3583750 T DE3583750 T DE 3583750T DE 3583750 D1 DE3583750 D1 DE 3583750D1
Authority
DE
Germany
Prior art keywords
monoclonal antibodies
cell lines
factor viiic
december
deposited
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585100224T
Other languages
English (en)
Inventor
George Kuo
Frank R Masiarz
Martha Truett
Pablo Valenzuela
Mirella Ezban Rasmussen
Jennifer Favaloro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nordisk Gentofte AS
Novartis Vaccines and Diagnostics Inc
Original Assignee
Nordisk Gentofte AS
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/570,062 external-priority patent/US5004804A/en
Priority claimed from US06/689,274 external-priority patent/US4716117A/en
Application filed by Nordisk Gentofte AS, Chiron Corp filed Critical Nordisk Gentofte AS
Application granted granted Critical
Publication of DE3583750D1 publication Critical patent/DE3583750D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE8585100224T 1984-01-12 1985-01-11 Hybridom-zellinien und monoklonale antikoerper gegen faktor-viii-c. Expired - Lifetime DE3583750D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/570,062 US5004804A (en) 1984-01-12 1984-01-12 Method and composition for preparation of factor VIIIC
US66491984A 1984-10-26 1984-10-26
US06/689,274 US4716117A (en) 1984-10-26 1985-01-07 Monoclonal antibodies to factor VIIIC

Publications (1)

Publication Number Publication Date
DE3583750D1 true DE3583750D1 (de) 1991-09-19

Family

ID=27416093

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8585100224T Expired - Lifetime DE3583750D1 (de) 1984-01-12 1985-01-11 Hybridom-zellinien und monoklonale antikoerper gegen faktor-viii-c.
DE198585100224T Pending DE152746T1 (de) 1984-01-12 1985-01-11 Monoklonale antikoerper gegen faktor-viii-c.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198585100224T Pending DE152746T1 (de) 1984-01-12 1985-01-11 Monoklonale antikoerper gegen faktor-viii-c.

Country Status (5)

Country Link
EP (2) EP0432134A1 (de)
JP (2) JPH0764879B2 (de)
AT (1) ATE66249T1 (de)
DE (2) DE3583750D1 (de)
DK (1) DK13485A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
WO1991004059A2 (en) * 1989-09-14 1991-04-04 Baxter International Inc. Method and useful apparatus for preparing pharmaceutical compositions
FR2662166A1 (fr) * 1990-05-18 1991-11-22 Fondation Nale Transfusion San Procede de preparation de facteur viii de tres haute purete comprenant une etape rapide d'immunoadsorption.
AT404429B (de) * 1995-06-09 1998-11-25 Immuno Ag Anti-plasma-antikörper-präparation
PT1095143E (pt) * 1998-05-08 2008-11-28 Sanquin Bloedvoorziening Inibidor para o diagnóstico e tratamento de doentes com hemofilia a
CN105859889B (zh) 2010-11-17 2020-01-07 中外制药株式会社 具有代替凝血因子viii的功能的功能的多特异性抗原结合分子
TWI700300B (zh) 2014-09-26 2020-08-01 日商中外製藥股份有限公司 中和具有第ｖｉｉｉ凝血因子（ｆｖｉｉｉ）機能替代活性的物質之抗體
TWI701435B (zh) * 2014-09-26 2020-08-11 日商中外製藥股份有限公司 測定ｆｖｉｉｉ的反應性之方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
DK172036B1 (da) * 1983-03-31 1997-09-22 Scripps Clinic Res Faktor VIII:C-koaguleringsmiddel, fremgangsmåde til fremstilling heraf samt fremgangsmåde til udvinding heraf
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides

Also Published As

Publication number Publication date
JPH0817697B2 (ja) 1996-02-28
EP0432134A1 (de) 1991-06-12
EP0152746B1 (de) 1991-08-14
JPS60210981A (ja) 1985-10-23
DE152746T1 (de) 1986-04-10
EP0152746A3 (en) 1987-05-27
JPH0764879B2 (ja) 1995-07-12
JPH0678761A (ja) 1994-03-22
ATE66249T1 (de) 1991-08-15
EP0152746A2 (de) 1985-08-28
DK13485A (da) 1985-07-13
DK13485D0 (da) 1985-01-11

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