DK13485A - Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie - Google Patents

Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie Download PDF

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Publication number
DK13485A
DK13485A DK13485A DK13485A DK13485A DK 13485 A DK13485 A DK 13485A DK 13485 A DK13485 A DK 13485A DK 13485 A DK13485 A DK 13485A DK 13485 A DK13485 A DK 13485A
Authority
DK
Denmark
Prior art keywords
monoclonal antibodies
cell line
factor viiic
december
deposited
Prior art date
Application number
DK13485A
Other languages
Danish (da)
English (en)
Other versions
DK13485D0 (da
Inventor
George Kuo
Frank R Masiarz
Martha Truett
Pablo Valenzuela
Mirella Ezban Rasmussen
Jennifer Favaloro
Original Assignee
Chiron Corp
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/570,062 external-priority patent/US5004804A/en
Priority claimed from US06/689,274 external-priority patent/US4716117A/en
Application filed by Chiron Corp, Nordisk Gentofte filed Critical Chiron Corp
Publication of DK13485D0 publication Critical patent/DK13485D0/da
Publication of DK13485A publication Critical patent/DK13485A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
DK13485A 1984-01-12 1985-01-11 Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie DK13485A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/570,062 US5004804A (en) 1984-01-12 1984-01-12 Method and composition for preparation of factor VIIIC
US66491984A 1984-10-26 1984-10-26
US06/689,274 US4716117A (en) 1984-10-26 1985-01-07 Monoclonal antibodies to factor VIIIC

Publications (2)

Publication Number Publication Date
DK13485D0 DK13485D0 (da) 1985-01-11
DK13485A true DK13485A (da) 1985-07-13

Family

ID=27416093

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13485A DK13485A (da) 1984-01-12 1985-01-11 Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie

Country Status (5)

Country Link
EP (2) EP0152746B1 (de)
JP (2) JPH0764879B2 (de)
AT (1) ATE66249T1 (de)
DE (2) DE152746T1 (de)
DK (1) DK13485A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
IE903354A1 (en) * 1989-09-14 1991-04-10 Baxter Int Method and useful apparatus for preparing pharmaceutical¹compositions
FR2662166A1 (fr) * 1990-05-18 1991-11-22 Fondation Nale Transfusion San Procede de preparation de facteur viii de tres haute purete comprenant une etape rapide d'immunoadsorption.
AT404429B (de) * 1995-06-09 1998-11-25 Immuno Ag Anti-plasma-antikörper-präparation
DE69939379D1 (de) * 1998-05-08 2008-10-02 Sanquin Bloedvoorziening Hemmstoff zur diagnose und behandlung von haemophilia a patienten
SI2644698T1 (en) 2010-11-17 2018-05-31 Chugai Seiyaku Kabushiki Kaisha MULTISPECIFIC ANTIGEN-TUBULAR MOLECULAR, WITH AN ALTERNATIVE FUNCTION TO THE FACTOR OF BLOOD VIOLATION VIII
TWI701435B (zh) 2014-09-26 2020-08-11 日商中外製藥股份有限公司 測定fviii的反應性之方法
TWI700300B (zh) 2014-09-26 2020-08-01 日商中外製藥股份有限公司 中和具有第viii凝血因子(fviii)機能替代活性的物質之抗體

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
FI841281A (fi) * 1983-03-31 1984-10-01 Scripps Clinic Res Ny faktor foer viii koagulenta polypeptider och deras monoklonala antikroppar.

Also Published As

Publication number Publication date
EP0152746A2 (de) 1985-08-28
EP0152746B1 (de) 1991-08-14
JPH0678761A (ja) 1994-03-22
JPH0817697B2 (ja) 1996-02-28
DE152746T1 (de) 1986-04-10
JPS60210981A (ja) 1985-10-23
EP0152746A3 (en) 1987-05-27
DK13485D0 (da) 1985-01-11
ATE66249T1 (de) 1991-08-15
JPH0764879B2 (ja) 1995-07-12
EP0432134A1 (de) 1991-06-12
DE3583750D1 (de) 1991-09-19

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