DK0454782T3 - Cancer-beslægtet haptaglobin (Hpr.) - Google Patents

Cancer-beslægtet haptaglobin (Hpr.)

Info

Publication number
DK0454782T3
DK0454782T3 DK90902901.9T DK90902901T DK0454782T3 DK 0454782 T3 DK0454782 T3 DK 0454782T3 DK 90902901 T DK90902901 T DK 90902901T DK 0454782 T3 DK0454782 T3 DK 0454782T3
Authority
DK
Denmark
Prior art keywords
hpr
hpr protein
haptaglobin
cancer
preparations
Prior art date
Application number
DK90902901.9T
Other languages
English (en)
Inventor
Francis P Kuhajda
Gary R Pasternack
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of DK0454782T3 publication Critical patent/DK0454782T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK90902901.9T 1989-01-17 1990-01-05 Cancer-beslægtet haptaglobin (Hpr.) DK0454782T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29772289A 1989-01-17 1989-01-17

Publications (1)

Publication Number Publication Date
DK0454782T3 true DK0454782T3 (da) 1997-10-27

Family

ID=23147472

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90902901.9T DK0454782T3 (da) 1989-01-17 1990-01-05 Cancer-beslægtet haptaglobin (Hpr.)

Country Status (10)

Country Link
EP (1) EP0454782B1 (da)
JP (1) JP2959837B2 (da)
KR (1) KR0174528B1 (da)
AT (1) ATE151882T1 (da)
AU (1) AU632535B2 (da)
CA (1) CA2045552C (da)
DE (1) DE69030494T2 (da)
DK (1) DK0454782T3 (da)
ES (1) ES2101695T3 (da)
WO (1) WO1990008324A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4417275A1 (de) * 1994-05-15 1996-02-22 Becker Hans Dieter Dr Verfahren und Kit zur Tumorprognose, -diagnostik und -prophylaxe
US6531277B2 (en) 1994-10-25 2003-03-11 The Curators Of The University Of Missouri Endometriosis-specific secretory protein
US6352842B1 (en) 1995-12-07 2002-03-05 Diversa Corporation Exonucease-mediated gene assembly in directed evolution
BE1010935A7 (nl) * 1997-02-19 1999-03-02 Delanghe Joris Richard Siegfri Fenotypering van humaan haptoglobine in serum of plasma door middel van quantitatieve agglutinatie met streptococcus antigenen.
GB0000901D0 (en) * 2000-01-14 2000-03-08 Isis Innovation Antiparasitic agent
JP4706093B2 (ja) * 2000-09-25 2011-06-22 富士レビオ株式会社 パルボウイルスの除去方法及び精製方法
CA2537955A1 (en) * 2003-09-05 2005-03-17 Royal Women's Hospital Diagnostic marker for ovarian cancer
DE102010008644A1 (de) 2010-02-15 2011-08-18 Bayer Schering Pharma Aktiengesellschaft, 13353 Zyklische Ketoenole zur Therapie
DE102011011040A1 (de) 2011-02-08 2012-08-09 Bayer Pharma Aktiengesellschaft (5s,8s)-3-(4'-Chlor-3'-fluor-4-methylbiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-on (Verbindung A) zur Therapie
WO2012110518A1 (de) 2011-02-17 2012-08-23 Bayer Pharma Aktiengesellschaft Substituierte 3-(biphenyl-3-yl)-8,8-difluor-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-one zur therapie
DE102011080405A1 (de) 2011-08-04 2013-02-07 Bayer Pharma AG Substituierte 3-(Biphenyl-3-yl)-8,8-difluor-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-one zur Therapie
DE102011080406A1 (de) 2011-08-04 2013-02-07 Bayer Pharma AG Substituierte 3-(Biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro8[4.5]dec-3-en-2-one
EP3467504A4 (en) * 2016-05-27 2020-02-12 Fujifilm Wako Pure Chemical Corporation METHOD FOR DETERMINING GASTROINTESTINAL CANCER

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946774A (en) * 1987-11-09 1990-08-07 Trustees Of Boston University Process for detecting cancer and for monitoring the effectiveness of cancer therapy

Also Published As

Publication number Publication date
DE69030494T2 (de) 1997-08-07
ES2101695T3 (es) 1997-07-16
WO1990008324A1 (en) 1990-07-26
JP2959837B2 (ja) 1999-10-06
AU5040690A (en) 1990-08-13
JPH04504110A (ja) 1992-07-23
EP0454782A1 (en) 1991-11-06
EP0454782B1 (en) 1997-04-16
KR910700463A (ko) 1991-03-15
CA2045552C (en) 2002-10-29
KR0174528B1 (ko) 1999-05-15
CA2045552A1 (en) 1990-07-26
DE69030494D1 (de) 1997-05-22
AU632535B2 (en) 1993-01-07
ATE151882T1 (de) 1997-05-15

Similar Documents

Publication Publication Date Title
JPS6447392A (en) Monoclonal antibody
NO175944C (no) Monoklonale antistoffer for anvendelse til in vitro påvisning av tumorassosiert mucinantigen, og hybridomcellelinjer som produserer disse
DK0454782T3 (da) Cancer-beslægtet haptaglobin (Hpr.)
ES2061730T3 (es) Nuevos anticuerpos.
JPS6434291A (en) Polynucleotide sequence, its production, polypeptide, fragment, antibody, polynucleotide specimen, diagnosis and estimation of malignant disease and examination of presence or absence of factor of malignant disease
FI92258B (fi) Onkostatiini-A:n käyttö diagnostisessa menetelmässä
DE69535719D1 (de) Fas-antigenbindender ligand
OA08485A (fr) Monoclonal antibodies and antigen for human non-small cell lung carcinoma and certain other human carcinomas.
DK0687295T3 (da) Human B-lymfoblastoidcellelinje, der secernerer anti-gangliosid-antistof
AU555699B2 (en) Pp13 protein from placenta
ATE70280T1 (de) Charakteristische polypeptide und antikoerper vom papillomavirus, diagnostische verfahren und dieselben verwendende impfungen.
GB2182949A (en) Monoclonal antibodies and antigens for human non-small cell lung carcinomas
DE3789781D1 (de) Antigene, Antikörper und Verfahren zur Identifizierung humaner metastatischer Tumoren und Zellinien zur Herstellung dieser Antikörper.
JPS5686194A (en) Novel protein and its manufacture
EP0282018A3 (en) Process for isolating basal membrane proteins from human or animal tissues
ATE58397T1 (de) Monoklonaler antikoerper geeignet zur spezifischen unterscheidung von humanen hepatokarzinomzellen.
EP0248147A3 (en) Method of determining the presence of cancer cells
WO1986002651A3 (en) Specific carbohydrate-binding proteins (lectins) of mammalian tumor cells
ATE87316T1 (de) Von protein ps2 abgeleitete peptide.
EP0095502A4 (en) MONOCLONIC HUMAN ANTIBODIES OR LYMPHOCINS IN CELL SEPARATION OR IN DIAGNOSIS OF BREAST CANCER.
AU573748B2 (en) Monoclonal antibody to cancer procoagulant and immunoassay
Ohkawa et al. An improved sensitive assay method for the heterogeneity of α-foetoprotein: possible application for early differential diagnosis
IL67944A0 (en) Antibodies and antigens useful in the diagnosis and treatment of cancer,methods for the production thereof and methods for testing for the presence of cancer cells using the same
NO874798D0 (no) Fremgangsmaate for fremstilling av monoklonale antistoffer ved dyrking av hybridom-cellelinjen lym-1.
FI923418A (fi) Monoklonaalinen vasta-aine