DE3580524D1 - Monoklonaler antikoerper geeignet zur spezifischen unterscheidung von humanen hepatokarzinomzellen. - Google Patents

Monoklonaler antikoerper geeignet zur spezifischen unterscheidung von humanen hepatokarzinomzellen.

Info

Publication number
DE3580524D1
DE3580524D1 DE8585108073T DE3580524T DE3580524D1 DE 3580524 D1 DE3580524 D1 DE 3580524D1 DE 8585108073 T DE8585108073 T DE 8585108073T DE 3580524 T DE3580524 T DE 3580524T DE 3580524 D1 DE3580524 D1 DE 3580524D1
Authority
DE
Germany
Prior art keywords
cells
human
hepatocarcinomic
monoclonal antibodies
antibodies suitable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585108073T
Other languages
English (en)
Inventor
Toshihiro Nakanishi
Yoshiaki Fukuda
Matsunoki-Danchi Miura
Hiroshi Nakazato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of DE3580524D1 publication Critical patent/DE3580524D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3038—Kidney, bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
DE8585108073T 1984-06-29 1985-06-28 Monoklonaler antikoerper geeignet zur spezifischen unterscheidung von humanen hepatokarzinomzellen. Expired - Lifetime DE3580524D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59134556A JPS6115897A (ja) 1984-06-29 1984-06-29 ヒト肝癌細胞を特異的に認識するモノクロ−ナル抗体

Publications (1)

Publication Number Publication Date
DE3580524D1 true DE3580524D1 (de) 1990-12-20

Family

ID=15131083

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585108073T Expired - Lifetime DE3580524D1 (de) 1984-06-29 1985-06-28 Monoklonaler antikoerper geeignet zur spezifischen unterscheidung von humanen hepatokarzinomzellen.

Country Status (5)

Country Link
US (1) US4820641A (de)
EP (1) EP0166458B1 (de)
JP (1) JPS6115897A (de)
AT (1) ATE58397T1 (de)
DE (1) DE3580524D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6357596A (ja) * 1986-08-29 1988-03-12 Nisshin Flour Milling Co Ltd モノクロ−ナル抗体、その製法およびそれからなる肝疾患診断剤
JPH0798000B2 (ja) * 1987-05-23 1995-10-25 萩原 義秀 ガン関連抗原特異的ヒト免疫グロブリン
JPH0829078B2 (ja) * 1991-11-25 1996-03-27 萩原 義秀 ガン関連抗原特異的ヒト免疫グロブリン生産性ヒト／ヒトハイブリドーマ
JPH05268988A (ja) * 1992-03-05 1993-10-19 Hagiwara Yoshihide ガン関連抗原特異的ヒト免疫グロブリン
US5760000A (en) * 1994-05-13 1998-06-02 University Technologies International,Inc. Inhibition of liver cancer by the use of GnRH and GnRH analogs
JP2004529849A (ja) * 2000-09-01 2004-09-30 インターナショナル バイオイムン システムズ，インコーポレーテッド 扁平上皮癌に対する特異的モノクローナル抗体の同定と開発

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579827A (en) * 1983-03-11 1986-04-01 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies to human gastrointestinal cancers and hybridoma method of production of the monoclonal antibodies

Also Published As

Publication number Publication date
US4820641A (en) 1989-04-11
EP0166458A3 (en) 1988-05-18
EP0166458B1 (de) 1990-11-14
JPS6115897A (ja) 1986-01-23
JPH0431674B2 (de) 1992-05-27
EP0166458A2 (de) 1986-01-02
ATE58397T1 (de) 1990-11-15

Similar Documents

Publication Publication Date Title
ATE58554T1 (de) Menschlicher hybridomfusionspartner zur herstellung menschlicher monoklonaler antikoerper.
MY108526A (en) Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
ATE85652T1 (de) Monoklonale antikoerper gegen humanen brustkrebs, korrespondierende hybridome, deren herstellung und verwendung.
AU2097692A (en) Method for the production of monoclonal antibodies utilizing a germfree animal
FI101937B1 (fi) Menetelmä monoklonaalisen vasta-aineen tuottamiseksi, joka reagoi ihmisen cachectiinin kanssa
IL67721A (en) Hybridoma cell lines,their preparation and their use for the production of human monoclonal antibodies
DE3587360T2 (de) Verfahren zur Herstellung von chimärischen monoklonalen Antikörpern.
GR3025644T3 (en) Improved monoclonal antibodies against the human alpha/beta t-cell receptor, their production and use
DE3852054D1 (de) Monoklonale Antikörper gegen Glycolipid-Antigene und ihre Verwendung.
DE240975T1 (de) Menschliches gamma-interferon-spezifisches rezeptorprotein, antikoerper gegen dieses protein, verfahren zur herstellung dieses proteins und dieses antikoerpers und dieses protein und diesen antikoerper enthaltende zusammensetzungen.
EP0198086A4 (de) Maus/mensch-hybridoma mit erzeugung von antiviralen menschlichen antikörpern, deren herstellung und antivirale menschliche monoklonale antikörper.
DE3581288D1 (de) Antileishmania monoklonale antikoerper, diese antikoerper ausscheidende hybridomas, von diesen antikoerpern erkannte leishmaniaantigene, verfahren zur herstellung und verwendung von diesen monoklonalen antikoerpern und antigenen.
ATA111789A (de) Humaner monoklonaler antikörper und hybridom zur herstellung desselben
DE3580524D1 (de) Monoklonaler antikoerper geeignet zur spezifischen unterscheidung von humanen hepatokarzinomzellen.
DE3585049D1 (de) Monoklonale antikoerper.
DE3583296D1 (de) Oncofetal spezifische monoklonale antikoerper, deren herstellung und verwendung.
ATE103989T1 (de) Monoklonale antikoerper gegen e7-protein des humanen papillomvirus typ 16, verfahren zu ihrer herstellung sowie ihre verwendung.
EP0287397A3 (en) Monoclonal antibody specific to human pancreatic phospholipase a2
DE3785175T2 (de) A-assoziierte h-antigene, spezifische monoklonale antikoerper und methoden zu deren verwendung zur blutgruppenbestimmung.
DK329789A (da) Monoklonalt antistof
DE3579808D1 (de) Anti-urokinase monoklonaler antikoerper, seine herstellung und verwendung.
ATE98491T1 (de) Verwendung von antigestagenen zur herstellung von arzneimitteln.
DE3881101D1 (de) Monoklonal-antikoerper und methode fuer die bereitung von hybridoma, produzierend diese antikoerper.
IL97827A0 (en) Monoclonal anti-igm antibodies,their production and use,and hybridomas for producing them
EP0251186A3 (en) Monoclonal antibody to human plasminogen, method for production thereof, assay reagent and kit comprising said antibody, and hybridoma producing said antibody

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee