ES2528403T3 - Sistemas informáticos farmacéuticos - Google Patents
Sistemas informáticos farmacéuticos Download PDFInfo
- Publication number
- ES2528403T3 ES2528403T3 ES06751858.9T ES06751858T ES2528403T3 ES 2528403 T3 ES2528403 T3 ES 2528403T3 ES 06751858 T ES06751858 T ES 06751858T ES 2528403 T3 ES2528403 T3 ES 2528403T3
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- Prior art keywords
- battery
- layer
- switch
- metallic
- computer systems
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/073—Intestinal transmitters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0026—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the transmission medium
- A61B5/0028—Body tissue as transmission medium, i.e. transmission systems where the medium is the human body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0031—Implanted circuitry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/076—Permanent implantations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4833—Assessment of subject's compliance to treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6861—Capsules, e.g. for swallowing or implanting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7282—Event detection, e.g. detecting unique waveforms indicative of a medical condition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/007—Marking tablets or the like
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K7/00—Methods or arrangements for sensing record carriers, e.g. for reading patterns
- G06K7/10—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation
- G06K7/10009—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves
- G06K7/10158—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves methods and means used by the interrogation device for reliably powering the wireless record carriers using an electromagnetic interrogation field
- G06K7/10168—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves methods and means used by the interrogation device for reliably powering the wireless record carriers using an electromagnetic interrogation field the powering being adversely affected by environmental influences, e.g. unwanted energy loss in the interrogation signal due to metallic or capacitive objects in the proximity of the interrogation device or in the proximity of the interrogated record carrier
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K7/00—Methods or arrangements for sensing record carriers, e.g. for reading patterns
- G06K7/10—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation
- G06K7/10009—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves
- G06K7/10366—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves the interrogation device being adapted for miscellaneous applications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01Q—ANTENNAS, i.e. RADIO AERIALS
- H01Q1/00—Details of, or arrangements associated with, antennas
- H01Q1/27—Adaptation for use in or on movable bodies
- H01Q1/273—Adaptation for carrying or wearing by persons or animals
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04B—TRANSMISSION
- H04B13/00—Transmission systems characterised by the medium used for transmission, not provided for in groups H04B3/00 - H04B11/00
- H04B13/005—Transmission systems in which the medium consists of the human body
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04W—WIRELESS COMMUNICATION NETWORKS
- H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
- H04W4/80—Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0204—Operational features of power management
- A61B2560/0214—Operational features of power management of power generation or supply
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
- A61B2560/0462—Apparatus with built-in sensors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/08—Sensors provided with means for identification, e.g. barcodes or memory chips
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
- A61B2562/162—Capsule shaped sensor housings, e.g. for swallowing or implantation
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49002—Electrical device making
- Y10T29/49117—Conductor or circuit manufacturing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Computer Networks & Wireless Communication (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Signal Processing (AREA)
- Electromagnetism (AREA)
- Artificial Intelligence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Psychiatry (AREA)
- Physiology (AREA)
- Optics & Photonics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Accommodation For Nursing Or Treatment Tables (AREA)
Abstract
Identificador que comprende un componente generador de señal que comprende: - una capa soporte de silicio (31); - una primera capa metálica de la batería (32); - una segunda capa metálica diferente de la batería (32); - una capa del circuito (38) dispuesta en la capa soporte de silicio entre la primera y segunda capas metálicas de la batería (204, 211, 212), en la que las diferentes capas metálicas de la batería están dispuestas para constituir electrodos de batería para la capa del circuito (38) cuando están en presencia de un líquido fisiológico; comprendiendo la capa del circuito un interruptor, interruptor que está configurado para producir, cuando el interruptor se cierra, una corriente por todo el cuerpo entre las capas metálicas de la batería que producen una diferencia de potencial detectable.
Description
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E06751858
22-01-2015
- Tabla 1
- Ánodo
- Cátodo
- Metales
- Magnesio, Zinc, Sodio (†), Litio (†) Hierro
- Sales
- Sales de cobre: yoduro, cloruro, bromuro, sulfato, formiato, (otros aniones posibles) sales de Fe3+: p. ej., ortofosfato, pirofosfato, (otros aniones posibles) Oxígeno (††) en platino, oro u otras superficies catalíticas
- Compuestos de intercalación
- Grafito con Li, K, Ca, Na, Mg Óxido de vanadio Óxido de manganeso
(†) Ánodos protegidos: algún material anódico de alta energía tales como Li, Na y otros metales alcalinos son inestables en su forma pura en presencia de agua u oxígeno. Sin embargo, estos pueden usarse en un medio acuoso si están estabilizados. Un ejemplo de esta estabilización es el denominado "ánodo de litio protegido" desarrollado por Polyplus Corporation (Berkeley, CA), donde una película de polímero se deposita en la superficie de metal de litio para protegerlo de la oxidación rápida y permitir su uso en el medio acuoso o el aire ambiente. (Polyplus tiene IP pendiente sobre ésta).
(††) Oxígeno disuelto también puede servir como cátodo. En este caso, el oxígeno disuelto en los fluidos
corporales se reduciría a OH-en una superficie catalítica adecuada tal como Pt u oro. También son
posibles otros catalizadores.
En algunas realizaciones, uno o ambos metales puede doparse con un metaloide, p. ej., para mejorar la salida de voltaje de la batería. Los metaloides que pueden utilizarse como agentes de dopaje en algunas realizaciones comprenden, pero no se limitan a: azufre, yodo y similares.
En algunas realizaciones, los materiales de los electrodos son yoduro de cobre (CuI) como ánodo y magnesio (Mg) como cátodo. Las realizaciones de la presente invención utilizan materiales de electrodo que no son perjudiciales para el cuerpo humano.
En algunas realizaciones, las baterías tienen un factor de forma pequeño. Las baterías pueden ser de 10 mm3 o menores, tal como de 1,0 mm3 o menores, como por ejemplo 0,1 mm3 o menor, como por ejemplo 0,02 mm3 o menores. Por lo tanto, en algunas realizaciones, el elemento de batería está dimensionado para tener una anchura que oscila entre aproximadamente 0,05 mm y aproximadamente 1 mm, tal como entre aproximadamente 0,1 mm y aproximadamente 0,2 mm; una longitud que oscila entre aproximadamente 0,05 mm y aproximadamente 1 mm, tal como entre aproximadamente 0,1 mm y aproximadamente 0,2 mm y una altura que oscila entre aproximadamente 0,1 mm y aproximadamente 1 mm, tal como entre aproximadamente 0,05 mm y aproximadamente 0,3 mm, como por ejemplo entre aproximadamente 0,1 mm y aproximadamente 0,2 mm.
Como se analiza a continuación, en algunas realizaciones, la batería tiene una división o configuración segmentada.
En algunas realizaciones, la batería es la que está libre de embalaje. De por sí, los electrodos están expuestos y no están protegidos por ninguna estructura de protección o de sellado. De por sí, después de la retirada del material de la matriz del principio activo/excipiente con el que la batería puede estar asociada, la batería en sí no comprende un embalaje de protección de manera que los electrodos están libres para contactar con el electrolito en el lugar fisiológico objetivo.
En algunas de estas realizaciones, la fuente de alimentación de la batería puede considerarse como una fuente de alimentación que aprovecha la electrólisis inversa en una solución iónica, tal como líquido gástrico, sangre, u otros
20
Claims (1)
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imagen1
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67614505P | 2005-04-28 | 2005-04-28 | |
US676145P | 2005-04-28 | ||
US69407805P | 2005-06-24 | 2005-06-24 | |
US694078P | 2005-06-24 | ||
US71368005P | 2005-09-01 | 2005-09-01 | |
US713680P | 2005-09-01 | ||
US79033506P | 2006-04-07 | 2006-04-07 | |
US790335P | 2006-04-07 | ||
PCT/US2006/016370 WO2006116718A2 (en) | 2005-04-28 | 2006-04-28 | Pharma-informatics system |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2528403T3 true ES2528403T3 (es) | 2015-02-09 |
Family
ID=37215570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES06751858.9T Active ES2528403T3 (es) | 2005-04-28 | 2006-04-28 | Sistemas informáticos farmacéuticos |
Country Status (14)
Country | Link |
---|---|
US (17) | US8847766B2 (es) |
EP (5) | EP2392258B1 (es) |
JP (6) | JP2008539047A (es) |
CN (3) | CN102379684B (es) |
AU (1) | AU2006239221C1 (es) |
CA (3) | CA2789097C (es) |
DK (1) | DK1889198T3 (es) |
ES (1) | ES2528403T3 (es) |
HK (2) | HK1113652A1 (es) |
IL (7) | IL186898A (es) |
PL (1) | PL1889198T3 (es) |
PT (1) | PT1889198E (es) |
SI (1) | SI1889198T1 (es) |
WO (1) | WO2006116718A2 (es) |
Families Citing this family (254)
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EP1770603A1 (en) * | 2005-10-03 | 2007-04-04 | Assa Abloy Identification Technology Group AB | Encapsulated transponder and method for manufacturing the same |
US8920343B2 (en) | 2006-03-23 | 2014-12-30 | Michael Edward Sabatino | Apparatus for acquiring and processing of physiological auditory signals |
US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
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