IT1213555B - 2 metiltiometildiidropiridine, un processo per laloro preparazione e composizioni farmaceutiche che le contengono. - Google Patents
2 metiltiometildiidropiridine, un processo per laloro preparazione e composizioni farmaceutiche che le contengono.Info
- Publication number
- IT1213555B IT1213555B IT8622648A IT2264886A IT1213555B IT 1213555 B IT1213555 B IT 1213555B IT 8622648 A IT8622648 A IT 8622648A IT 2264886 A IT2264886 A IT 2264886A IT 1213555 B IT1213555 B IT 1213555B
- Authority
- IT
- Italy
- Prior art keywords
- aryl
- alkoxycarbonyl
- heteroaryl
- methylomethyl
- hydropyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8622648A IT1213555B (it) | 1986-12-11 | 1986-12-11 | 2 metiltiometildiidropiridine, un processo per laloro preparazione e composizioni farmaceutiche che le contengono. |
PH36155A PH25966A (en) | 1986-12-11 | 1987-12-02 | 2-methylthiomethyl-dihydro-pyridines and pharmaceutical compositions containing them |
AT87118145T ATE96152T1 (de) | 1986-12-11 | 1987-12-08 | 2-methylthiomethyl-dihydropyridine, verfahren zur herstellung und pharmazeutische zusammenstellungen, die sie enthalten. |
EP87118145A EP0271059B1 (en) | 1986-12-11 | 1987-12-08 | 2-Methylthiomethyl-dihydropyridines, a process for their preparation and pharmaceutical compositions containing them |
DE87118145T DE3787878D1 (de) | 1986-12-11 | 1987-12-08 | 2-Methylthiomethyl-dihydropyridine, Verfahren zur Herstellung und pharmazeutische Zusammenstellungen, die sie enthalten. |
US07/131,393 US4971984A (en) | 1986-12-11 | 1987-12-10 | 2-methylthiomethyl-dihydropyridines and pharmaceutical compositions containing them |
KR870014104A KR880007468A (ko) | 1986-12-11 | 1987-12-10 | 2-메틸티오메틸-디히드로피리딘, 그의 제조 방법 및 이를 함유하는 제약 조성물 |
AU82294/87A AU611872B2 (en) | 1986-12-11 | 1987-12-10 | 2-methylthiomethyl-dihydropyridines, a process for their preparation and pharmaceutical compositions containing them |
ZA879301A ZA879301B (en) | 1986-12-11 | 1987-12-10 | 2-methylthiomethyl-dihydropyridines,a process for their preparation and pharmaceutical compositions containing them |
JP62313104A JPS63170360A (ja) | 1986-12-11 | 1987-12-10 | 2−メチルチオメチル−ジヒドロピリジン、該ジヒドロピリジンの製法、及び該ジヒドロピリジンを含む薬剤組成物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8622648A IT1213555B (it) | 1986-12-11 | 1986-12-11 | 2 metiltiometildiidropiridine, un processo per laloro preparazione e composizioni farmaceutiche che le contengono. |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8622648A0 IT8622648A0 (it) | 1986-12-11 |
IT1213555B true IT1213555B (it) | 1989-12-20 |
Family
ID=11198832
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8622648A IT1213555B (it) | 1986-12-11 | 1986-12-11 | 2 metiltiometildiidropiridine, un processo per laloro preparazione e composizioni farmaceutiche che le contengono. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4971984A (it) |
EP (1) | EP0271059B1 (it) |
JP (1) | JPS63170360A (it) |
KR (1) | KR880007468A (it) |
AT (1) | ATE96152T1 (it) |
AU (1) | AU611872B2 (it) |
DE (1) | DE3787878D1 (it) |
IT (1) | IT1213555B (it) |
PH (1) | PH25966A (it) |
ZA (1) | ZA879301B (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU199796B (en) * | 1985-08-06 | 1990-03-28 | Boehringer Biochemia Srl | Process for producing 2-thiomethyl-substituted-1,4-dihydropyridines and pharmaceutical compositions comprising such compounds |
EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
US6699892B2 (en) | 2002-06-04 | 2004-03-02 | Yung Shin Pharmaceutical Industrial Co., Ltd. | Pharmaceutically acceptable salt of amlodipine and method of preparing the same |
CN103259027A (zh) | 2005-04-28 | 2013-08-21 | 普罗透斯数字保健公司 | 药物信息系统 |
CA2663377A1 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
EP2398500B1 (en) | 2009-02-20 | 2019-03-13 | 2-BBB Medicines B.V. | Glutathione-based drug delivery system |
CA2760945A1 (en) | 2009-05-06 | 2010-11-11 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CS228917B2 (en) * | 1981-03-14 | 1984-05-14 | Pfizer | Method of preparing substituted derivatives of 1,4-dihydropyridine |
NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
DE3207982A1 (de) * | 1982-03-05 | 1983-09-08 | Bayer Ag, 5090 Leverkusen | Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln |
DK161312C (da) * | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
IL68604A0 (en) * | 1982-05-21 | 1983-09-30 | Haessle Ab | Processes for preparing therapeutically active dihydropyridines and intermediates for the processes |
US4515799A (en) * | 1983-02-02 | 1985-05-07 | Pfizer Inc. | Dihydropyridine anti-ischaemic and antihypertensive agents |
GB8306666D0 (en) * | 1983-03-10 | 1983-04-13 | Pfizer Ltd | Therapeutic agents |
GB8412208D0 (en) * | 1984-05-12 | 1984-06-20 | Pfizer Ltd | Quinolone inotropic agents |
GB8415386D0 (en) * | 1984-06-15 | 1984-07-18 | Pfizer Ltd | Therapeutic agents |
DE3426732A1 (de) * | 1984-07-20 | 1986-01-23 | Bayer Ag, 5090 Leverkusen | Material fuer stuetzverbaende |
EP0200524A3 (en) * | 1985-05-03 | 1987-06-16 | Pfizer Limited | Dihydropyridine calcium antagonists |
FI862343A (fi) * | 1985-06-17 | 1986-12-18 | Warner Lambert Co | Foerfarande foer framstaellning av terapeutiskt verkande 1,4-dihydropyridinfoereningar. |
HU199796B (en) * | 1985-08-06 | 1990-03-28 | Boehringer Biochemia Srl | Process for producing 2-thiomethyl-substituted-1,4-dihydropyridines and pharmaceutical compositions comprising such compounds |
IT1204421B (it) * | 1986-06-27 | 1989-03-01 | Boehringer Biochemia Srl | 2-(aminoalchiltio)metil-1,4-diidropiridine,un metodo per la loro preparazione e composizioni farmaceutiche che le contengono |
GB8526411D0 (en) * | 1985-10-25 | 1985-11-27 | Pfizer Ltd | Dihydropyridines |
GB8527698D0 (en) * | 1985-11-09 | 1985-12-11 | Pfizer Ltd | Dihydropyridine antiischaemic & antihypertensive agents |
EP0225175A3 (en) * | 1985-11-28 | 1988-12-28 | FISONS plc | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof |
-
1986
- 1986-12-11 IT IT8622648A patent/IT1213555B/it active
-
1987
- 1987-12-02 PH PH36155A patent/PH25966A/en unknown
- 1987-12-08 EP EP87118145A patent/EP0271059B1/en not_active Expired - Lifetime
- 1987-12-08 AT AT87118145T patent/ATE96152T1/de not_active IP Right Cessation
- 1987-12-08 DE DE87118145T patent/DE3787878D1/de not_active Expired - Lifetime
- 1987-12-10 JP JP62313104A patent/JPS63170360A/ja active Pending
- 1987-12-10 KR KR870014104A patent/KR880007468A/ko not_active Application Discontinuation
- 1987-12-10 AU AU82294/87A patent/AU611872B2/en not_active Ceased
- 1987-12-10 US US07/131,393 patent/US4971984A/en not_active Expired - Fee Related
- 1987-12-10 ZA ZA879301A patent/ZA879301B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US4971984A (en) | 1990-11-20 |
EP0271059B1 (en) | 1993-10-20 |
AU8229487A (en) | 1988-06-16 |
ZA879301B (en) | 1988-08-31 |
KR880007468A (ko) | 1988-08-27 |
IT8622648A0 (it) | 1986-12-11 |
ATE96152T1 (de) | 1993-11-15 |
JPS63170360A (ja) | 1988-07-14 |
DE3787878D1 (de) | 1993-11-25 |
AU611872B2 (en) | 1991-06-27 |
EP0271059A1 (en) | 1988-06-15 |
PH25966A (en) | 1992-01-13 |
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