IT1213440B - 2-ditioalchil-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche chele contengono. - Google Patents
2-ditioalchil-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche chele contengono.Info
- Publication number
- IT1213440B IT1213440B IT8622881A IT2288186A IT1213440B IT 1213440 B IT1213440 B IT 1213440B IT 8622881 A IT8622881 A IT 8622881A IT 2288186 A IT2288186 A IT 2288186A IT 1213440 B IT1213440 B IT 1213440B
- Authority
- IT
- Italy
- Prior art keywords
- groups
- dithioalkyl
- dihydropyridine
- contain
- preparation
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000003107 substituted aryl group Chemical group 0.000 abstract 2
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000006193 alkinyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical group 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- -1 cyano, nitro, benzoyl Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8622881A IT1213440B (it) | 1986-12-24 | 1986-12-24 | 2-ditioalchil-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche chele contengono. |
| JP62323622A JPS63170361A (ja) | 1986-12-24 | 1987-12-21 | ２‐ジチオアルキル‐ジヒドロピリジン、該ジヒドロピリジンの製法、及び該ジヒドロピリジンを含有する薬剤組成物 |
| AT87119081T ATE73775T1 (de) | 1986-12-24 | 1987-12-22 | 2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten. |
| DE8787119081T DE3777575D1 (de) | 1986-12-24 | 1987-12-22 | 2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten. |
| EP87119081A EP0272694B1 (en) | 1986-12-24 | 1987-12-22 | 2-dithioalkyl-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them |
| CA000555177A CA1313526C (en) | 1986-12-24 | 1987-12-23 | 2-dithioalkyl-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them |
| US07/333,815 US4956369A (en) | 1986-12-24 | 1989-04-06 | 2-dithioalkyl-dihydropyridines and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8622881A IT1213440B (it) | 1986-12-24 | 1986-12-24 | 2-ditioalchil-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche chele contengono. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8622881A0 IT8622881A0 (it) | 1986-12-24 |
| IT1213440B true IT1213440B (it) | 1989-12-20 |
Family
ID=11201500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8622881A IT1213440B (it) | 1986-12-24 | 1986-12-24 | 2-ditioalchil-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche chele contengono. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4956369A (it) |
| EP (1) | EP0272694B1 (it) |
| JP (1) | JPS63170361A (it) |
| AT (1) | ATE73775T1 (it) |
| CA (1) | CA1313526C (it) |
| DE (1) | DE3777575D1 (it) |
| IT (1) | IT1213440B (it) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4284634A (en) * | 1975-07-02 | 1981-08-18 | Fujisawa Pharmaceutical Co., Ltd. | 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same |
| NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
| DE3207982A1 (de) * | 1982-03-05 | 1983-09-08 | Bayer Ag, 5090 Leverkusen | Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln |
| IL68604A0 (en) * | 1982-05-21 | 1983-09-30 | Haessle Ab | Processes for preparing therapeutically active dihydropyridines and intermediates for the processes |
| US4690935A (en) * | 1983-03-31 | 1987-09-01 | Wayne State University | Inhibition of tumor growth and metastasis with calcium channel blocker compounds |
| EP0169009A3 (en) * | 1984-07-17 | 1988-08-31 | FISONS plc | Novel dihydropyridine derivatives and their production, formulation and use as pharmaceuticals |
| IL78642A0 (en) * | 1985-05-03 | 1986-08-31 | Pfizer | Dihydropyridines and pharmaceutical compositions containing them |
-
1986
- 1986-12-24 IT IT8622881A patent/IT1213440B/it active
-
1987
- 1987-12-21 JP JP62323622A patent/JPS63170361A/ja active Pending
- 1987-12-22 AT AT87119081T patent/ATE73775T1/de active
- 1987-12-22 EP EP87119081A patent/EP0272694B1/en not_active Expired - Lifetime
- 1987-12-22 DE DE8787119081T patent/DE3777575D1/de not_active Expired - Lifetime
- 1987-12-23 CA CA000555177A patent/CA1313526C/en not_active Expired - Fee Related
-
1989
- 1989-04-06 US US07/333,815 patent/US4956369A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0272694A1 (en) | 1988-06-29 |
| DE3777575D1 (de) | 1992-04-23 |
| US4956369A (en) | 1990-09-11 |
| CA1313526C (en) | 1993-02-09 |
| ATE73775T1 (de) | 1992-04-15 |
| IT8622881A0 (it) | 1986-12-24 |
| EP0272694B1 (en) | 1992-03-18 |
| JPS63170361A (ja) | 1988-07-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES522199A0 (es) | Un procedimiento para preparar un derivado de dihidropiridina. | |
| DK0389282T3 (da) | Xanthinderivater, fremgangsmåde til deres fremstilling og deres farmaceutiske anvendelse | |
| DK536581A (da) | Fremgangsmaade til fremstilling af carbonsyreamider | |
| EA200100090A2 (ru) | Новые пиперидин-4-сульфонамидные производные, способ их получения и содержащие их фармацевтические композиции | |
| ATE66913T1 (de) | Amidverbindungen, verfahren zu ihrer herstellung und zusammensetzung zur aktivierung gastromotorischer funktionen. | |
| PT82897B (pt) | Processo de preparacao de derivados de di-hidropiridazinona | |
| ATE141606T1 (de) | Cephemverbindungen und verfahren zu ihrer herstellung | |
| FI98372B (fi) | Menetelmä farmaseuttisesti käyttökelpoisten -D-fenyylitioksylosidien valmistamiseksi | |
| IT1213440B (it) | 2-ditioalchil-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche chele contengono. | |
| EA199900765A1 (ru) | Новые производные эритромицина, способ их получения и их применение в качестве лекарственных средств | |
| IT1204948B (it) | 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono. | |
| NZ194777A (en) | N-aminoalkyl-n'-(2-chloroethyl)-n'-nitroso-ureas and pharmaceutical compositions | |
| DE3775526D1 (de) | Bakterizide pyridobenzothiazinderivate mit langer wirkungsdauer. | |
| IT1205114B (it) | 2-selenometil-1,4-diidropiridine,procedimento per la loro preparazione e composizioni farmaceutiche che le contengono | |
| DE69011748D1 (de) | Biphenyl-Derivate, Verfahren zu deren Herstellung und deren Zwischenprodukte. | |
| ES2009209A6 (es) | Procedimiento para la obtencion de dihidropiridinlactoles. | |
| ATE195936T1 (de) | Bis-imide derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitung | |
| EA200200379A2 (ru) | Новые соединения пиримидин-4-она, способ их получения и содержащие их фармацевтические композиции | |
| IL80402A0 (en) | Dihydropyridines and pharmaceutical compositions containing them | |
| DK99588A (da) | 2-(aminoalkythio)methyl-1,4-dihydropyridin-forbindelser, en fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem | |
| ATE96144T1 (de) | 2-aminoacetamid derivate. | |
| DE69022660D1 (de) | Verfahren zur Herstellung von Carbamatderivaten des Lankacidines. |