ES2135443T3 - Vehiculo mejorado para la administracion oral de omeprazol. - Google Patents

Vehiculo mejorado para la administracion oral de omeprazol.

Info

Publication number
ES2135443T3
ES2135443T3 ES93201611T ES93201611T ES2135443T3 ES 2135443 T3 ES2135443 T3 ES 2135443T3 ES 93201611 T ES93201611 T ES 93201611T ES 93201611 T ES93201611 T ES 93201611T ES 2135443 T3 ES2135443 T3 ES 2135443T3
Authority
ES
Spain
Prior art keywords
alkaline
oral administration
omeprazola
nucleus
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93201611T
Other languages
English (en)
Inventor
Kurt Lovgren
Ake Pilbrant
Mitsuru Yasumura
Satoshi Morigaki
Minoru Oda
Naohiro Ohishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Astra AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26290693&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2135443(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra AB filed Critical Astra AB
Application granted granted Critical
Publication of ES2135443T3 publication Critical patent/ES2135443T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE DESCRIBEN UNAS MEJORAS EN VEHICULOS PARA ADMINISTRACION ORAL DE SUSTANCIAS FARMACEUTICAMENTE ACTIVAS DE ACIDO LABILO PROPENSAS A LA DECOLORACION QUE CONTIENEN OMEPRAZOLA. LA ADMINISTRACION DEL COMPUESTO COMPRENDE UN NUCLEO QUE CONTIENE LA OMEPRAZOLA JUNTO CON UN COMPONENTE DE REACCION ALCALINA, O UNA SAL ALCALINA DE OMEOPRAZOLA MEZCLADA OPCIONALMENTE CON DICHO COMPONENTE, ADOPTANDO LA FORMA, BIEN DE UN NUMERO DE PEQUEÑAS CUENTAS QUE FORMAN UNA TABLETA O UNA TABLETA COMO TAL, Y COMPRENDE UN REVESTIMIENTO HECHO DE UNA O MAS CAPAS SUBPROTECTORAS DE REACCION INERTE QUE COMPRENDEN UNOS EXCIPIENTES DE TABLETA QUE SON SOLUBLES O DISGREGADOS RAPIDAMENTE EN AGUA; O COMPONENTES POLIMERICO SOLUBLES EN AGUA O EN FORMA DE CAPAS, CONTENIENDO OPCIONALMENTE CIERTOS COMPONENTES ALCALINOS DE PH TAMPON, ENTRE EL NUCLEO DE REACCION ALCALINA Y UNA CAPA DE REVESTIMIENTO EXTERIOR ENTERICA
ES93201611T 1986-04-30 1987-04-16 Vehiculo mejorado para la administracion oral de omeprazol. Expired - Lifetime ES2135443T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB08610572A GB2189698A (en) 1986-04-30 1986-04-30 Coated omeprazole tablets
SG154294A SG154294G (en) 1986-04-30 1994-10-21 New pharmaceutical preparation for oral use

Publications (1)

Publication Number Publication Date
ES2135443T3 true ES2135443T3 (es) 1999-11-01

Family

ID=26290693

Family Applications (3)

Application Number Title Priority Date Filing Date
ES93201611T Expired - Lifetime ES2135443T3 (es) 1986-04-30 1987-04-16 Vehiculo mejorado para la administracion oral de omeprazol.
ES87850127T Expired - Lifetime ES2006457T3 (es) 1986-04-30 1987-04-16 Nueva preparacion farmaceutica para uso oral.
ES92107179T Expired - Lifetime ES2091971T3 (es) 1986-04-30 1987-04-16 Uso de material de nucleo especifico y capas para obtener formulaciones farmaceuticas estables a la decoloracion de omeprazol.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES87850127T Expired - Lifetime ES2006457T3 (es) 1986-04-30 1987-04-16 Nueva preparacion farmaceutica para uso oral.
ES92107179T Expired - Lifetime ES2091971T3 (es) 1986-04-30 1987-04-16 Uso de material de nucleo especifico y capas para obtener formulaciones farmaceuticas estables a la decoloracion de omeprazol.

Country Status (35)

Country Link
US (1) US4786505A (es)
EP (3) EP0247983B1 (es)
JP (2) JPS62258320A (es)
KR (1) KR910004579B1 (es)
CN (1) CN1020852C (es)
AR (1) AR240250A1 (es)
AT (3) ATE84215T1 (es)
CA (1) CA1292693C (es)
CY (1) CY1810A (es)
DD (1) DD273197A5 (es)
DE (3) DE247983T1 (es)
DK (1) DK169988B1 (es)
DZ (1) DZ1077A1 (es)
ES (3) ES2135443T3 (es)
FI (1) FI90393C (es)
GB (1) GB2189698A (es)
GR (4) GR890300058T1 (es)
HK (2) HK135294A (es)
HR (1) HRP920854B1 (es)
HU (1) HU196708B (es)
IE (1) IE61416B1 (es)
IL (1) IL82911A (es)
IS (1) IS1917B (es)
LT (1) LT3699B (es)
LV (2) LV10357B (es)
NO (1) NO174239C (es)
NZ (1) NZ220096A (es)
PH (1) PH25701A (es)
PL (1) PL151631B1 (es)
PT (1) PT84785B (es)
RU (2) RU1820837C (es)
SG (1) SG154294G (es)
SI (1) SI8710681A8 (es)
YU (1) YU46192B (es)
ZA (1) ZA872378B (es)

Families Citing this family (356)

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US5202128A (en) * 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
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