ATE203906T1 - Zubereitung zur perkutanen verabreichung enthaltend 6-amino-5-chloro-1-isopropyl-2-(4- methyl-1-piperazinyl)benzimidazol - Google Patents
Zubereitung zur perkutanen verabreichung enthaltend 6-amino-5-chloro-1-isopropyl-2-(4- methyl-1-piperazinyl)benzimidazolInfo
- Publication number
- ATE203906T1 ATE203906T1 AT97922189T AT97922189T ATE203906T1 AT E203906 T1 ATE203906 T1 AT E203906T1 AT 97922189 T AT97922189 T AT 97922189T AT 97922189 T AT97922189 T AT 97922189T AT E203906 T1 ATE203906 T1 AT E203906T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- benzimidazole
- piperazinyl
- chloro
- isopropyl
- Prior art date
Links
- QEANRFDFBNUCJR-UHFFFAOYSA-N 6-chloro-2-(4-methylpiperazin-1-yl)-3-propan-2-ylbenzimidazol-5-amine Chemical compound N=1C2=CC(Cl)=C(N)C=C2N(C(C)C)C=1N1CCN(C)CC1 QEANRFDFBNUCJR-UHFFFAOYSA-N 0.000 title abstract 2
- -1 benzimidazole compound Chemical class 0.000 abstract 2
- YHMYGUUIMTVXNW-UHFFFAOYSA-N 1,3-dihydrobenzimidazole-2-thione Chemical compound C1=CC=C2NC(S)=NC2=C1 YHMYGUUIMTVXNW-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229920006243 acrylic copolymer Polymers 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000012790 adhesive layer Substances 0.000 abstract 1
- 239000010410 layer Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8134914A JPH09315976A (ja) | 1996-05-29 | 1996-05-29 | 経皮投与用製剤 |
| PCT/JP1997/001781 WO1997045121A1 (fr) | 1996-05-29 | 1997-05-26 | Preparation destinee a une administration percutanee |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE203906T1 true ATE203906T1 (de) | 2001-08-15 |
Family
ID=15139492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97922189T ATE203906T1 (de) | 1996-05-29 | 1997-05-26 | Zubereitung zur perkutanen verabreichung enthaltend 6-amino-5-chloro-1-isopropyl-2-(4- methyl-1-piperazinyl)benzimidazol |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6077528A (de) |
| EP (1) | EP0965342B1 (de) |
| JP (1) | JPH09315976A (de) |
| CN (1) | CN1219874A (de) |
| AT (1) | ATE203906T1 (de) |
| DE (1) | DE69706070T2 (de) |
| WO (1) | WO1997045121A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10167956A (ja) * | 1996-12-11 | 1998-06-23 | Hisamitsu Pharmaceut Co Inc | セロトニン受容体拮抗薬含有経皮投与製剤 |
| US6132761A (en) * | 1997-09-05 | 2000-10-17 | Nitto Denko Corporation | Percutaneous absorption preparation |
| JP5334346B2 (ja) * | 1999-08-10 | 2013-11-06 | 久光製薬株式会社 | ロール状外用貼付剤 |
| JP5021124B2 (ja) | 2001-08-29 | 2012-09-05 | 日東電工株式会社 | 医療用粘着組成物、それを用いた医療用粘着テープおよび経皮吸収用テープ製剤 |
| JP4311728B2 (ja) * | 2003-12-10 | 2009-08-12 | ニチバン株式会社 | 経皮吸収型貼付剤 |
| CA2548864C (en) * | 2005-06-06 | 2012-12-11 | Nitto Denko Corporation | Percutaneous absorption-type pharmaceutical preparation |
| EP1731143B1 (de) * | 2005-06-06 | 2008-11-26 | Nitto Denko Corporation | Pharmazeutische Zusammensetzung zur perkutane Absorption unter Verwendung von einem Metalchlorid, vorzugsweise Natriumchlorid, zur Vorbeugung von Kohäsionsschwäche |
| JP2008101027A (ja) * | 2008-01-17 | 2008-05-01 | Nitto Denko Corp | 経皮吸収型製剤 |
| JP2012031071A (ja) * | 2010-07-28 | 2012-02-16 | Nitto Denko Corp | 貼付剤および貼付製剤 |
| EP2551102B1 (de) * | 2011-07-29 | 2014-12-03 | 3M Innovative Properties Company | Selbstklebendes Schaumhaftmittel |
| JP7282701B2 (ja) * | 2020-01-23 | 2023-05-29 | 久光製薬株式会社 | パップ剤 |
| CN113423394A (zh) | 2019-02-14 | 2021-09-21 | 久光制药株式会社 | 泥罨剂 |
| WO2020172418A1 (en) * | 2019-02-22 | 2020-08-27 | Elkem Silicones USA Corp. | Drug delivery silicone compositon to improve active ingredient elution |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55131075A (en) * | 1979-03-31 | 1980-10-11 | Nitto Electric Ind Co Ltd | Adhesive tape |
| TW201744B (de) * | 1991-07-02 | 1993-03-11 | Kanebou Textile Co Ltd | |
| JPH0748258A (ja) * | 1993-06-03 | 1995-02-21 | Kanebo Ltd | 経皮投与用製剤 |
-
1996
- 1996-05-29 JP JP8134914A patent/JPH09315976A/ja active Pending
-
1997
- 1997-05-26 US US09/194,522 patent/US6077528A/en not_active Expired - Fee Related
- 1997-05-26 WO PCT/JP1997/001781 patent/WO1997045121A1/ja not_active Ceased
- 1997-05-26 DE DE69706070T patent/DE69706070T2/de not_active Expired - Fee Related
- 1997-05-26 AT AT97922189T patent/ATE203906T1/de not_active IP Right Cessation
- 1997-05-26 EP EP97922189A patent/EP0965342B1/de not_active Expired - Lifetime
- 1997-05-26 CN CN97195045A patent/CN1219874A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US6077528A (en) | 2000-06-20 |
| EP0965342B1 (de) | 2001-08-08 |
| JPH09315976A (ja) | 1997-12-09 |
| CN1219874A (zh) | 1999-06-16 |
| DE69706070D1 (de) | 2001-09-13 |
| EP0965342A1 (de) | 1999-12-22 |
| DE69706070T2 (de) | 2002-05-02 |
| EP0965342A4 (de) | 2000-02-09 |
| WO1997045121A1 (fr) | 1997-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |