MX383752B - Forma de dosificación oral de liberación sostenida gastro retentiva de un secuestrante de ácido biliar. - Google Patents
Forma de dosificación oral de liberación sostenida gastro retentiva de un secuestrante de ácido biliar.Info
- Publication number
- MX383752B MX383752B MX2015009055A MX2015009055A MX383752B MX 383752 B MX383752 B MX 383752B MX 2015009055 A MX2015009055 A MX 2015009055A MX 2015009055 A MX2015009055 A MX 2015009055A MX 383752 B MX383752 B MX 383752B
- Authority
- MX
- Mexico
- Prior art keywords
- bile acid
- acid sequestrant
- agonists
- sustained
- dosage form
- Prior art date
Links
- 229920000080 bile acid sequestrant Polymers 0.000 title abstract 4
- 239000006186 oral dosage form Substances 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
- 239000000556 agonist Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000003185 4 aminobutyric acid B receptor stimulating agent Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940069428 antacid Drugs 0.000 abstract 1
- 239000003159 antacid agent Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 abstract 1
- 229960001340 histamine Drugs 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 229940126409 proton pump inhibitor Drugs 0.000 abstract 1
- 239000000612 proton pump inhibitor Substances 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Physiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se describen en la presente nuevas composiciones y métodos para controlar la liberación del secuestrante del ácido biliar al estómago con el fin de tratar o prevenir trastornos del tracto GI superior o trastornos de la garganta. Los métodos generalmente incluyen la administración a un paciente en tal necesidad de una cantidad terapéuticamente efectiva de una composición farmacéutica que comprende al menos un secuestrante del ácido biliar dispersado en una matriz polimérica. La composición del secuestrante del ácido biliar puede administrarse sola o en combinación con al menos un inhibidor de la bomba de protón, y opcionalmente uno o más agentes seleccionados de antiácidos, antagonistas del receptor H2 de histamina, agonistas de ?-ácido aminobutírico ß (GABA-B), profármacos de agonistas GABA-B, antagonistas de la bomba ácida, inhibidores de proteasa y agonistas GC-C.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361752726P | 2013-01-15 | 2013-01-15 | |
| US201361914804P | 2013-12-11 | 2013-12-11 | |
| PCT/US2014/011450 WO2014113377A1 (en) | 2013-01-15 | 2014-01-14 | Gastro-retentive sustained-release oral dosage form of a bile acid sequestrant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015009055A MX2015009055A (es) | 2016-05-16 |
| MX383752B true MX383752B (es) | 2025-03-11 |
Family
ID=50031605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015009055A MX383752B (es) | 2013-01-15 | 2014-01-14 | Forma de dosificación oral de liberación sostenida gastro retentiva de un secuestrante de ácido biliar. |
Country Status (11)
| Country | Link |
|---|---|
| US (6) | US20160015644A1 (es) |
| EP (2) | EP2945614B1 (es) |
| JP (2) | JP6716255B2 (es) |
| CN (2) | CN108057028A (es) |
| AU (1) | AU2014207680B2 (es) |
| BR (1) | BR112015016917B1 (es) |
| CA (1) | CA2898362C (es) |
| EA (1) | EA201591338A1 (es) |
| ES (1) | ES2906114T3 (es) |
| MX (1) | MX383752B (es) |
| WO (1) | WO2014113377A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX383752B (es) * | 2013-01-15 | 2025-03-11 | Ironwood Pharmaceuticals Inc | Forma de dosificación oral de liberación sostenida gastro retentiva de un secuestrante de ácido biliar. |
| JP6499591B2 (ja) | 2013-02-25 | 2019-04-10 | シナジー ファーマシューティカルズ インコーポレイテッド | 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト |
| TW201618783A (zh) | 2014-08-07 | 2016-06-01 | 艾森塔製藥公司 | 以布魯頓(Bruton)氏酪胺酸激酶(BTK)佔據和BTK再合成速率為基礎之治療癌症、免疫和自體免疫疾病及發炎性疾病之方法 |
| WO2016126625A1 (en) | 2015-02-03 | 2016-08-11 | Ironwood Pharmaceuticals, Inc. | Methods of treating upper gastrointestinal disorders in ppi refractory gerd |
| CN105362244A (zh) * | 2015-11-26 | 2016-03-02 | 青岛海之源智能技术有限公司 | 考来烯胺缓释片及制备方法 |
| CN105456219A (zh) * | 2015-12-28 | 2016-04-06 | 青岛海之星生物科技有限公司 | 一种考来替泊缓释片及制备方法 |
| CN105520919A (zh) * | 2015-12-28 | 2016-04-27 | 青岛海之星生物科技有限公司 | 一种考来替泊缓释胶囊及制备方法 |
| WO2018119191A1 (en) * | 2016-12-21 | 2018-06-28 | Ironwood Pharmaceuticals Inc. | Methods of treating irritable bowel syndrome with modified or delayed release formulations of linaclotide |
| CA3070082A1 (en) * | 2017-07-19 | 2019-01-24 | Ironwood Pharmaceuticals, Inc. | Efficacy of a gastro-retentive bile acid sequestrant dosage form |
| EP3501503A1 (en) * | 2017-12-22 | 2019-06-26 | Cosmo Technologies Ltd. | Solid delivery composition |
| CN111110647A (zh) * | 2018-10-31 | 2020-05-08 | 浙江京新药业股份有限公司 | 含盐酸考来维仑的药物组合物及其制备方法 |
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| SE416649B (sv) | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| JPS5692217A (en) | 1979-12-26 | 1981-07-25 | Kowa Co | Easily absorbable enzyme preparation |
| US4359465A (en) | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
| US4472409A (en) | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
| AU545463B2 (en) | 1982-06-25 | 1985-07-18 | Kowa Co. Ltd. | Benzoyl piperacine esters |
| SE8300736D0 (sv) | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| JPS59222484A (ja) | 1983-06-02 | 1984-12-14 | Kowa Co | テトラヒドロナフチルカルボン酸フエニルエステル誘導体 |
| JPS608225A (ja) | 1983-06-29 | 1985-01-17 | Kowa Co | 腸管吸収医薬組成物 |
| IL75400A (en) | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
| JPS6150978A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| AU4640985A (en) | 1984-08-31 | 1986-03-06 | Nippon Chemiphar Co. Ltd. | Benzimidazole derivatives |
| US4738975A (en) | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
| CA1327010C (en) | 1986-02-13 | 1994-02-15 | Tadashi Makino | Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production |
| GB2189698A (en) | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
| GB2189699A (en) | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated acid-labile medicaments |
| FI90544C (fi) | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
| FI96860C (fi) | 1987-06-17 | 1996-09-10 | Eisai Co Ltd | Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi |
| JP2916205B2 (ja) | 1990-04-28 | 1999-07-05 | 帝國製薬株式会社 | 生理活性ペプチド |
| JP2916206B2 (ja) | 1990-04-28 | 1999-07-05 | 帝國製薬株式会社 | 生理活性ペプチド |
| DK223790D0 (da) | 1990-09-18 | 1990-09-18 | Novo Nordisk As | Proteaseholdig detergentkomposition |
| CA2053527C (en) | 1990-10-17 | 2002-03-12 | Takashi Sohda | Pyridine derivatives, their production and use |
| US5167483A (en) | 1990-12-24 | 1992-12-01 | Gardiner Samuel W | Method for utilizing angular momentum in energy conversion devices and an apparatus therefore |
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| US5877192A (en) | 1993-05-28 | 1999-03-02 | Astra Aktiebolag | Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole |
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| NZ598728A (en) * | 2006-12-22 | 2013-09-27 | Ironwood Pharmaceuticals Inc | Compositions comprising bile acid sequestrants for treating esophageal disorders |
| US8741918B2 (en) * | 2007-06-21 | 2014-06-03 | Veroscience Llc | Parenteral formulations of dopamine agonists |
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| MX383752B (es) * | 2013-01-15 | 2025-03-11 | Ironwood Pharmaceuticals Inc | Forma de dosificación oral de liberación sostenida gastro retentiva de un secuestrante de ácido biliar. |
| CN103585128A (zh) * | 2013-11-18 | 2014-02-19 | 北京泰德制药股份有限公司 | 一种包含盐酸考来维仑的药物组合物及其制备方法 |
-
2014
- 2014-01-14 MX MX2015009055A patent/MX383752B/es unknown
- 2014-01-14 EP EP14702387.3A patent/EP2945614B1/en not_active Not-in-force
- 2014-01-14 CN CN201711090819.1A patent/CN108057028A/zh active Pending
- 2014-01-14 JP JP2015552890A patent/JP6716255B2/ja not_active Expired - Fee Related
- 2014-01-14 EA EA201591338A patent/EA201591338A1/ru unknown
- 2014-01-14 BR BR112015016917-1A patent/BR112015016917B1/pt not_active IP Right Cessation
- 2014-01-14 US US14/760,883 patent/US20160015644A1/en not_active Abandoned
- 2014-01-14 CN CN201480015783.9A patent/CN105338958A/zh active Pending
- 2014-01-14 EP EP21202140.6A patent/EP3991719A1/en not_active Withdrawn
- 2014-01-14 WO PCT/US2014/011450 patent/WO2014113377A1/en not_active Ceased
- 2014-01-14 AU AU2014207680A patent/AU2014207680B2/en not_active Ceased
- 2014-01-14 CA CA2898362A patent/CA2898362C/en active Active
- 2014-01-14 ES ES14702387T patent/ES2906114T3/es active Active
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2017
- 2017-02-27 US US15/443,747 patent/US20170266116A1/en not_active Abandoned
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2018
- 2018-10-05 JP JP2018189952A patent/JP6755920B2/ja not_active Expired - Fee Related
-
2020
- 2020-09-30 US US17/039,662 patent/US20210015754A1/en not_active Abandoned
-
2021
- 2021-05-07 US US17/314,213 patent/US20210267903A1/en not_active Abandoned
- 2021-12-20 US US17/556,210 patent/US20220110876A1/en not_active Abandoned
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2022
- 2022-08-05 US US17/881,714 patent/US20220370367A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EA201591338A1 (ru) | 2016-01-29 |
| US20220110876A1 (en) | 2022-04-14 |
| EP2945614A1 (en) | 2015-11-25 |
| ES2906114T3 (es) | 2022-04-13 |
| US20210015754A1 (en) | 2021-01-21 |
| EP2945614B1 (en) | 2021-11-24 |
| JP2018203787A (ja) | 2018-12-27 |
| EP3991719A1 (en) | 2022-05-04 |
| CA2898362A1 (en) | 2014-07-24 |
| NZ709924A (en) | 2021-02-26 |
| BR112015016917A2 (es) | 2017-08-15 |
| AU2014207680B2 (en) | 2018-09-06 |
| US20170266116A1 (en) | 2017-09-21 |
| BR112015016917B1 (pt) | 2022-08-30 |
| US20210267903A1 (en) | 2021-09-02 |
| US20160015644A1 (en) | 2016-01-21 |
| WO2014113377A1 (en) | 2014-07-24 |
| JP6755920B2 (ja) | 2020-09-16 |
| CN105338958A (zh) | 2016-02-17 |
| HK1214529A1 (zh) | 2016-07-29 |
| MX2015009055A (es) | 2016-05-16 |
| AU2014207680A1 (en) | 2015-08-27 |
| CN108057028A (zh) | 2018-05-22 |
| US20220370367A1 (en) | 2022-11-24 |
| JP6716255B2 (ja) | 2020-07-01 |
| JP2016508992A (ja) | 2016-03-24 |
| CA2898362C (en) | 2020-09-01 |
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