AR047726A1 - Metodos y reactivos para el tratamiento de trastornos inflamatorios - Google Patents

Metodos y reactivos para el tratamiento de trastornos inflamatorios

Info

Publication number
AR047726A1
AR047726A1 ARP040104212A ARP040104212A AR047726A1 AR 047726 A1 AR047726 A1 AR 047726A1 AR P040104212 A ARP040104212 A AR P040104212A AR P040104212 A ARP040104212 A AR P040104212A AR 047726 A1 AR047726 A1 AR 047726A1
Authority
AR
Argentina
Prior art keywords
treatment
compound
reagents
methods
patient
Prior art date
Application number
ARP040104212A
Other languages
English (en)
Original Assignee
Combinatorx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34619466&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR047726(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Combinatorx Inc filed Critical Combinatorx Inc
Publication of AR047726A1 publication Critical patent/AR047726A1/es

Links

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A—HUMAN NECESSITIES
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)

Abstract

Método para tratar un paciente con diagnostico de, o en situacion de riesgo de desarrollar un trastorno inmunoinflamatorio al administrar un compuesto tricíclico y, opcionalmente, un corticosteroide u otro compuesto al paciente. Composicion farmacéutica que contiene un compuesto tricíclico y un corticosteroide u otro compuesto para el tratamiento o la prevencion de un trastorno inmunoinflamatorio. Composicion farmacéutica y método para disminuir la secrecion o produccion de citoquina proinflamatoria en un paciente. Un equipo que comprende una composicion e instrucciones para la administracion de dicha composicion. Método para identificar combinaciones de compuestos utiles para suprimir la secrecion de citoquinas proinflamatorias y para el tratamiento de un trastorno inmunoinflamatorio.
ARP040104212A 2003-11-13 2004-11-15 Metodos y reactivos para el tratamiento de trastornos inflamatorios AR047726A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52044603P 2003-11-13 2003-11-13

Publications (1)

Publication Number Publication Date
AR047726A1 true AR047726A1 (es) 2006-02-15

Family

ID=34619466

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040104212A AR047726A1 (es) 2003-11-13 2004-11-15 Metodos y reactivos para el tratamiento de trastornos inflamatorios

Country Status (17)

Country Link
US (2) US20050187200A1 (es)
EP (1) EP1691744A4 (es)
JP (1) JP2007511521A (es)
KR (1) KR20060118536A (es)
CN (1) CN1901863A (es)
AR (1) AR047726A1 (es)
AU (1) AU2004291084A1 (es)
BR (1) BRPI0416591A (es)
CA (1) CA2545615A1 (es)
IL (1) IL175610A0 (es)
IS (1) IS8497A (es)
NO (1) NO20062363L (es)
RU (1) RU2006120408A (es)
SG (1) SG148186A1 (es)
TW (1) TW200529861A (es)
WO (1) WO2005048927A2 (es)
ZA (1) ZA200604250B (es)

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Publication number Priority date Publication date Assignee Title
EP1824336A4 (en) * 2004-12-02 2009-10-14 Univ North Carolina INHIBITION OF PHOSPHORYLATION HSP27 TO TREAT VESICATION DISORDERS
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
WO2007019888A2 (en) * 2005-08-12 2007-02-22 Ctg Pharma S.R.L. Therapeutic compositions containing mesalamine and a co-agent for treating colon diseases
WO2007103468A2 (en) * 2006-03-07 2007-09-13 Vertex Pharmaceuticals Incorporated Use of vx-702 for treating rheumatoid arthritis
CN101965514A (zh) * 2008-01-03 2011-02-02 艾博特生物技术有限公司 预测化合物在治疗银屑病中的长期功效
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
WO2011011594A2 (en) * 2009-07-23 2011-01-27 Shriners Hospitals For Children Intracellular toll-like receptors pathways and axonal degeneration
MX2015009105A (es) * 2013-01-14 2016-06-21 Infirst Healthcare Ltd Composiciones en solucion solida y su uso en inflamacion cronica.
KR101567735B1 (ko) * 2014-12-09 2015-11-09 동국대학교 산학협력단 면역 조절제 및 글루코사민을 포함하는 건선 예방, 개선 또는 치료용 조성물
SG11201903209TA (en) * 2016-10-14 2019-05-30 Van Andel Res Institute Structures and mechanism for the design of highly potent glucocorticoids
US20190262353A1 (en) * 2016-10-25 2019-08-29 Uti Limited Partnership Treatment for progressive multiple sclerosis
CA3075191A1 (en) * 2017-09-07 2019-03-14 Uti Limited Partnership Use of mirtazapine in the treatment of inflammatory disorders, autoimmune disease and pbc
CN107913279A (zh) * 2017-11-16 2018-04-17 钟汝华 一种治疗多种皮肤病的药膏

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107306A (en) * 1973-01-16 1978-08-15 The Regents Of The University Of Michigan Process for treating proliferative skin disease
US4034087A (en) * 1973-12-17 1977-07-05 The Regents Of The University Of Michigan Pharmaceutical composition and process of treatment
US5286730A (en) * 1991-09-17 1994-02-15 American Home Products Corporation Method of treating immunoinflammatory disease
US6011005A (en) * 1997-09-18 2000-01-04 The Picower Institute For Medical Research Prevention of pregnancy miscarriages
US6140337A (en) * 1997-12-23 2000-10-31 Schering Corporation Methods for the treatment of mental disorders
US5900249A (en) * 1998-02-09 1999-05-04 Smith; David J. Multicomponent pain relief topical medication
US6677326B2 (en) * 1999-03-15 2004-01-13 Arakis, Ltd. Corticosteroid formulation comprising less than 2.5 mg prednisolone for once daily administration
NZ530764A (en) * 2001-07-09 2008-07-31 Combinatorx Inc Composition comprising a tricyclic antidepressant and a corticosteroid administered simutaneously or within 14 days for treatment of inflammatory disorders

Also Published As

Publication number Publication date
AU2004291084A1 (en) 2005-06-02
TW200529861A (en) 2005-09-16
CA2545615A1 (en) 2005-06-02
IS8497A (is) 2006-06-02
BRPI0416591A (pt) 2007-01-30
WO2005048927A2 (en) 2005-06-02
US20090075951A1 (en) 2009-03-19
RU2006120408A (ru) 2007-12-20
WO2005048927A3 (en) 2006-01-26
IL175610A0 (en) 2006-09-05
CN1901863A (zh) 2007-01-24
SG148186A1 (en) 2008-12-31
KR20060118536A (ko) 2006-11-23
EP1691744A4 (en) 2007-12-26
ZA200604250B (en) 2007-11-28
NO20062363L (no) 2006-08-11
JP2007511521A (ja) 2007-05-10
EP1691744A2 (en) 2006-08-23
US20050187200A1 (en) 2005-08-25

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